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<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YBX1</accession>
    <name>A0ABR3YBX1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_006979</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000477">
        <property type="protein sequence ID" value="KAL1885352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1885352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="59" mass="6253" checksum="34697F869F76374A" modified="2025-10-08" version="1" fragment="single">CEDFVGAHPESYTEAYWAINSIKIYKATAEEVPEALPTGLLPVAVSSTNTPKATNTLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFB5</accession>
    <name>A0ABR3YFB5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WIBG Mago-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006855</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000394">
        <property type="protein sequence ID" value="KAL1886922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039333">
        <property type="entry name" value="PYM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015362">
        <property type="entry name" value="WIBG_mago-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036348">
        <property type="entry name" value="WIBG_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22959:SF0">
        <property type="entry name" value="PARTNER OF Y14 AND MAGO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22959">
        <property type="entry name" value="PYM PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09282">
        <property type="entry name" value="Mago-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01273">
        <property type="entry name" value="Mago-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101931">
        <property type="entry name" value="Pym (Within the bgcn gene intron protein, WIBG), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WIBG Mago-binding" evidence="2">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1886922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="262" mass="28500" checksum="099B91AB68B2D389" modified="2025-10-08" version="1">MSPTQPPTSPTIAGIVVDDGGNRVIPESIRPDGTTRKAIRIRPGFRPAEDIERFRPRAAQGRAQHHARGPPGAEYTDRPTPPSRIASEINNTPPRTPSSSVASARVSPSARTPISYTPSTPIRSYSNQSATPKSPVYLKMSWRRDDSLQKTATPSESLESVTLPAPVEKESRSIEDAEVPSTEPEAPAIEVEVDREKKARGLKKKLKQARDLQEKESDGKTLLPEQLAKIGKIDELVLELKTLGLSCDDDKGGVVTKEGEDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG75</accession>
    <name>A0ABR3YG75_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">beta-glucosidase</fullName>
            <ecNumber evidence="5 14">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Cpir12675_006805</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 14">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="5 14"/>
    <dbReference type="EMBL" id="JAWDJO010000380">
        <property type="protein sequence ID" value="KAL1886965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF5">
        <property type="entry name" value="BETA-GLUCOSIDASE M-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12 14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13 14" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Fibronectin type III-like" evidence="15">
        <location>
            <begin position="666"/>
            <end position="734"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1886965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="745" mass="81665" checksum="824B68DD8BEEA573" modified="2025-10-08" version="1">MTASVKREHPDIQPPEIKGLDSWHYARQKAARLVAVMTLEERVSLTSGVPSPNGCVGWIAPVERVGFPGLCTDDAGNGLRNADFVSAWPSGIHVGASWNRNLSYFRAYGMGDEFKNKGVNLLLGPVVGPMGRIVRGGRNWEGIAVDPYLAGQLVSSTVKGHQDAGVMTSTKHFIANEQETYRWPRNGIEAISSNIDDRTLHEFYLWPFQDAVKAGTVNVMCSYQRLNNSYVCQNSKALNGLLKTELGFQGFVVSDWRAQHSGVASALSGLDMAMPTHEGFWGDQLVKAVQNGSVPEARVNDMATRIIASWYKLGQDKTFTSPGFGRPGSIRASHPTIDARRKEHRKALFDGAVEGHVLVKNLNQSLPLSSPRMISIFGYSAKSPDSVNPSSWISFSDPLDPEFFSSAIALNGTMISGGGSGATSPSNLVSPFEAVKMRAFQDGTAVFWDFESAEPEIDPASDACLVFGNAWAAEKFDRPNLHDDYTDGLIKHVASECANTIVVFHNSGPRLVAQFADNDNITAIIFGHLPGQDTGPAITSILYGDTDPSGRLPYTVARNESDYFSAGPDLPEGKFQIFPQSNFSEGVFVDYRYFDEHAIEPHYEFGFGLSYTTFSYTNLTMRPSPNVNLDQLPSGPVVEGGQKDLWDVLYIVSVTVKNTGSRDGKDVPQLYVRIPADGAPGKQLRGFDKVQIATAESVQVTFPLTRRDLSFWDVTTQKWRLPRGEFGVFIGQSSRRIVLEGSFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG96</accession>
    <name>A0ABR3YG96_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribosome production factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RPF1</name>
        <name evidence="3" type="ORF">Cpir12675_006791</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000376">
        <property type="protein sequence ID" value="KAL1886980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10480">
        <property type="entry name" value="Probable brix-domain ribosomal biogenesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044281">
        <property type="entry name" value="IMP4/RPF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22734:SF3">
        <property type="entry name" value="RIBOSOME PRODUCTION FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22734">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Brix" evidence="2">
        <location>
            <begin position="196"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1886980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="430" mass="49238" checksum="6140838CB744516A" modified="2025-10-08" version="1">MAPSSSRPRGSFSSISISKGANRLKRQSLFIEHKRKVTKERHEARHRRRKEESRDPLLKAERLATNKPQTIEDKRVWDTAEDIENAPLGAAVDVKRAQRAQQKREAAEAMDEDLSEKEDSDSESDRDSMLDSEDEEEMDERKHLKEKKQKLKMAQKVAADAAEENPDDEPASIHFQMTTDLLAKKFPTLFDDSPRPAPKILVTTSLNSTLHDEAHLLCELFPNSEYIRRTAHRYGYKYSLREISKFAYNRDYSAVVMLREDQKKPTGLTVTFLPSGPTATFSISSWLLGKYIPGHGNATGHIPELIFNGFRTPLGILTARMLGNLFPNQPELVGRTVMTFHSQRDFIFVRRHRYVFRNRRETEKKIAGADGKELKGVEDIRSGLQELGPRFTLKLRRVDKGIGKAGSEGEDATQWEWKAGMEKDRKRFNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGE0</accession>
    <name>A0ABR3YGE0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Mechanosensitive ion channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_006856</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000396">
        <property type="protein sequence ID" value="KAL1886917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016688">
        <property type="entry name" value="MscS-like_plants/fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_beta-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058650">
        <property type="entry name" value="Msy1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31323:SF15">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN MSY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31323">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN MSY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25886">
        <property type="entry name" value="Msy1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017209">
        <property type="entry name" value="Memb_At2g17000_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="228"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="579"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="523"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="25"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="123"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="792"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="917"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="837"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="857"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="922"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="954"/>
            <end position="968"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR017209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1886917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="994" mass="112444" checksum="6FF03410D3AE8F28" modified="2025-10-08" version="1">MSHAQSPGIQINDAIDNVPLEKLSTSSLHRPPQIAVSDTQSAAISSNTHLSPTSPISPHYYHQQHAQLKTSGTALSIGVPLGPTTTAQQHLADPLAHPEARRSHEMRLHDELEMLRTEQMISSREQELQRIGSRQPTSDDDDAHYNPNSDAILSSVKPPPQATPDSSAILYRLWIWLKKFPRIFRYIFYAAPGAAILLIPVLIGKYAFKAEDHAVGGDDGVYLEWFGIWLEIMWGSLWLSRMVTSLMPYIFKAVASMMGSVNSKKWKDIGRDLELHTALFLWMLAILVSTKTILENHRVPTTTEEDREELDWVKVVIRVIISTFVLSCLNLLEKIGIQWIAGSFHQRTYAVRIAQNKDDVSKLVRLYEHSKIHFHPMDSIWQPVNSRTNSSGYRAPLHAMRQNARAAWDKFGNVAGRIGNDFMGRKANSNHPRKVVGELLRSAYHSRALARILYRSLKGLHSHSMETIGADKNISNEPTNDDTIHDGDAQNSVHEKSSIPQEFPNFDDMEQLVYLEDFKVVFSDEEEAEAAFAIFDKDMNGDISMEEFEGVCYEIHLEKKAIAASLKDLDSVINKLDRVLVGIVLIISILVFVSIISGSAAAALTSAGTTILGLSWLLQATTQEFLQSLVFVFVKHPFDVGDRVTVYGNSGNLGRGDDYYVTEISLWYTEFKKMEGHIVQAPNSILNTLFILNQRRSNALADVVSLQVRFGTTQPQIEELKERMMVFVDSNRRDYQARILTEVRTLDDMQSATVNFIFFHKSNFQNELLRLSRHNRFLTELMQQMCEVGIQPPFKNQPGGSAENPVYWKYTNNNGTHEPPPFARDDDNASVHRAPRQTENGSQNPVPSNNHAEHFIQETNQQNTSDSRSATERLPALRHNVPFDDFQDVYSMRKDEYPPNRWNSVSGANASHLRMRRGTGAEVSSLSQQESHQTGSMHPRLSLEQNSTHEPGIRRMTTTMSKMSSTSRRFWHRPRARTQSDNRPMDVLPDGSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGT6</accession>
    <name>A0ABR3YGT6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_006743</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000365">
        <property type="protein sequence ID" value="KAL1887023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052542">
        <property type="entry name" value="Cholesterol_Oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47470">
        <property type="entry name" value="CHOLESTEROL OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47470:SF1">
        <property type="entry name" value="FAD-DEPENDENT OXIDOREDUCTASE 2 FAD BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="233"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1887023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1392" mass="153788" checksum="8AC528ADEB367173" modified="2025-10-08" version="1">MKAFTAPFKKGRKVSNGPATLTAGDGLDSSSVPLLSEDAFPCELPPSPASCSSPQPNFKKDSRWVSASKLERGAFPPSPPSVDEVPDEYFFLNNKKPPPSFFSTAKKSYSCSQSRAEASVQSFANNSTGSNGFPRLSRAVPLMRNSYDFIVIGSGYGGGIAASRLARSQGPDGRNSVCILERGCEKWPGEYPSSPTSSLSQVRCSGVLDPGNARRFKIPIKGGNSKGLYHIHMGKGLSCFMGNGLGGTSLINANIFLPADKGVLGLPTWPQEIREDPQSLDQYYDKAAAVLEPETYPNSWPKLHKVELLKRQARLMGMRDKFRKIPQTTRFNNGSNSCGVEMRSSTLSGEDITGINDGSKNTTLVTYVADAWNWGAEIFCECEVRYVLECTGPEGGYIVYYSWGDLGRTHFHDVFKGDLMWVHAKKGVFFGAGAIGTTEILLRSKEMGLPLSDHIGQEVSGNGDMLAFGYNTDFESNSLGQAHPNPENPTGPTINAAIDNREGHDSPLDGWILEDGAVSSPMVPFLQAMLELVPNSVQPQTKRSMTSKLRSGLASLGSWMLGPYSKRGAMNRTQIYLVMTHDGAQARMTLEDDKLSLEFPGLSRSGHVTRIHDILAHATSLVGGSVMSHPFYSLLGKQQVTVHPLGGARMAYDGTGKTGGCNHAGELFTGQGPEVHPGLIVVDAAAVPTSLGVNPLATISALAERSIDIFAKRYNLTISEEKNGSLDLFGKPRHPFMGKVGQMQTAIMEHKEVARTQNAMRSFDEDKADGYAFTEIMSGYIHRLNNTKLVEDDLDTYRLAQRVARGRLEAARFFLTIQTFDIRSYVGNIDHPAVMTGTVACPTLPGSPFMVQRGDFQLLSVDPKRPNTLNLVYDFDMWGTDRQMLHFHGYKILDSSVELSPIRFWKASSTLYVTITRPTPGRIRNKDDPNDWRHDQVIAKGILNIKLGDFVSEVLSLTPTGSSLLRKLSSSVAYFKFMTSHAFPLFLGRFGRLQYPTPNYIGYVNRTHPQATYTITARDGVQTPLYVFEPTNSSIEIRNVVMIAGAAVDHQVFALPTIPYNTVNYMTRAGYRVFAGVHRFGLVNIARDDWTVFDAREDIRGVIQFVRENYPEHNSPDNKVYTVAHCMGSVSLSIGLLTGDIPSNWIWGISCSQTFMTPIWSPPNMIKAMKGPIPLDTLYKKLAGSWMSCQPSTGDRFIQRALTQLLRLYPQPRQEFCNNAACHRTSLAFGRCWNHRNLNEATHRQMDRFFNGVNMTLMDVLMRQGSIGSVTTNGPDYTPLVTDENVERLRGLPILQFVGADNAVLSPAATQRSYDILVKRFGLASEDGQVQYRRLEIPGYGHLDSWMGRNSWRDVYPHVRAEMDRVTRGPAYTFAEPVDRFSTMTANGVLMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH18</accession>
    <name>A0ABR3YH18_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000316">
        <property type="protein sequence ID" value="KAL1887478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="442" mass="47150" checksum="F1DF2929E9972D4A" modified="2025-10-08" version="1">MPNPIALTVGIAAITVAAAAAIIIYESPEVRRYAKDVHRRFAKAMPGRRGAPRSNGASVDTDTEDYEFQEPLYNRPEDADGFMMSSQHRNRRRSSFGLHARSNAGADSDMDLDSLDNDDDVTGEARRRQREELDFWNAIHESQEMENARRIADEHESLEQLASKFDDVLNADAATGAAGTDGSTYNSGANIHGDGSGLRRRGDNQSQSQPQSRGFGFSYPPVYLSRGVDTGAIPATSADAAAAAATTHTATSVFDDVLDIYSATNSGDHADVESCAAIPYTDNNASVNIEDSETASSLTLDRAATPTSETPMNPFSDINEVSSQDDAFASIQAWAEQSNVSFFSPMPMSPHAVPSTPTARSSELAQSVISLADEVSDEGAMTPTDSASVVSSSVHVAMLDNDTVSNKGSRYDVISQTDGMLTPASWSEVGSVVSDDDMHVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHG1</accession>
    <name>A0ABR3YHG1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial FAD carrier protein flx1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">FLX1</name>
        <name evidence="12" type="ORF">Cpir12675_006608</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000333">
        <property type="protein sequence ID" value="KAL1887292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044712">
        <property type="entry name" value="SLC25A32-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45683">
        <property type="entry name" value="MITOCHONDRIAL NICOTINAMIDE ADENINE DINUCLEOTIDE TRANSPORTER 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="8"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="120"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="241"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1887292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="328" mass="35590" checksum="F9EAF798459A3F96" modified="2025-10-08" version="1">MPSQSPLSPASIESIAGLMAGSVATLVVHPLDIVKTRMQIYRSATATGGKLELTTLGVLRSLVAHDTPMRAFYRGLTPNLVGNAAGWASFFFFKAKAEQLIMSLRSERHHAHAHNDGGFLAPYEHFLASAMAGATTTMLTNPIWVLKTRMLSSNRASEGAYQSMSQGVRAIYHTEGLSGFYRGVLVSLMGVSHGAVQFAVYDPLKRVYLATQPGGRNGSRINLPATKSSGGEHIQRLDVQATLAISTLAKLVAGAATYPYQVIRARMQNYDSEKRFGKGVAGVAGRVYREEGLRGFYRGLGPAVLRVMPATWVTFLVYENVKHQLKAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHJ3</accession>
    <name>A0ABR3YHJ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Septin-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_006422</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000298">
        <property type="protein sequence ID" value="KAL1887746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="3">
        <location>
            <begin position="269"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="47"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="656"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="733" mass="78522" checksum="8F3CAD7936051ED1" modified="2025-10-08" version="1">MRNSRGHTSSAAYRRPFSSGPPPGSDSSLLMPTTFFLGTEDEMDAVRGRNNITTNSAAPCHPHSNLRHAATSKYKRRSTSVVSSAASSINRDCDVTPPQESVAPLRRPTPRAQPGNDYDSESYEGDSTSDFGIETLASLPPSEPVDVGDADLQSLRSLQSATPSHHSPLHPFFGQTPQALSPTYSRFGTIASSSALSSSSSLGESLAATFSDYYYAASQTDADAAVPGNFGLDSSQAQNDMCNSNGASQFIMPTLTLPSRRPFTDVGKALGRIKILVAGASDTGKSSLIRATLESCTHIIHADPTKASGSPVSGSLPQPPPLCETCASSKPHPPWWTKVNSRRSSSSAGPQARHEELLDRNITFLEAPGFDPSLKKQTQQAMSIVSQSLTAILQTSSSLCECNDDADVVRILGGDESHLVSVVLYLVSPTGLTKCDVEFMKTLQPLTNMIPIISRSDTIPKSALQALKETVASSISSAGIVPFTFQEQDLDSTPFIYSASSLFTLEPDREEMLAPSDLSRLIDDIFTQDGASWLRHASAKKALLWCKSLQSQYSPTALQLRPYEWQLSSLSNSAHTSPSGPGSNRWCSFDFGQTITAHRQSRIKIEPWARNLQRSLYNIRLPHCDQVLSEIDSEMDLARSAGGGALVQRNVVGSAGGVRHGHRDGHGQGQVEGHRRQRSRAETPSMDQDPLGLLTTIRGIKYTGWSAVQMIGAVGLVGGGFSLGGLPSGMAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHX8</accession>
    <name>A0ABR3YHX8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Malate synthase</fullName>
            <ecNumber evidence="3 9">2.3.3.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ACU9</name>
        <name evidence="13" type="ORF">Cpir12675_006536</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>glyoxylate + acetyl-CoA + H2O = (S)-malate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18181"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the malate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.9" evidence="3 9"/>
    <dbReference type="EMBL" id="JAWDJO010000317">
        <property type="protein sequence ID" value="KAL1887472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004474">
        <property type="term" value="F:malate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00727">
        <property type="entry name" value="malate_synt_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.360">
        <property type="entry name" value="Malate synthase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1220.12">
        <property type="entry name" value="Malate synthase, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044856">
        <property type="entry name" value="Malate_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011076">
        <property type="entry name" value="Malate_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006252">
        <property type="entry name" value="Malate_synthA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019830">
        <property type="entry name" value="Malate_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001465">
        <property type="entry name" value="Malate_synthase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048355">
        <property type="entry name" value="MS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048356">
        <property type="entry name" value="MS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046363">
        <property type="entry name" value="MS_N_TIM-barrel_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01344">
        <property type="entry name" value="malate_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42902">
        <property type="entry name" value="MALATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42902:SF1">
        <property type="entry name" value="MALATE SYNTHASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20659">
        <property type="entry name" value="MS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20656">
        <property type="entry name" value="MS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01274">
        <property type="entry name" value="MS_TIM-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001363">
        <property type="entry name" value="Malate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51645">
        <property type="entry name" value="Malate synthase G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00510">
        <property type="entry name" value="MALATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4 9" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="7" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Malate synthase N-terminal" evidence="11">
        <location>
            <begin position="10"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="Malate synthase TIM barrel" evidence="10">
        <location>
            <begin position="164"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="Malate synthase C-terminal" evidence="12">
        <location>
            <begin position="415"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF20656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF20659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1887472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="542" mass="60963" checksum="5C74E534D8B3646D" modified="2025-10-08" version="1">MASTDFLLQGVNVLAPVQEQQRKILTPQALAFVALLHRTFNNTRKNLLERRKIRQAEIDRGVLPDFLPETKAVREDPSWKGAKPAPGLVDRRVEITGPTDRKMVVNALNSDVWTYMADFEDSSAPTWESMVNGQVNLYDANRRQIDFKLGPKEYKLRTDRTLPTLIVRPRGWHLEEKHVTIDGEPVSGSLFDFGLYFFHNAHQTVKQGLGPYFYLPKMESHLEARLWNDVFNLAQDTIGMPRGTIRGTVLIETILAAFEMEEIIYELRDHSSGLNCGRWDYIFSVIKKFRQNPNFVLPDRASVTMTSPFMDAYVKLLIQTCHKRGVHAMGGMAAQIPIKDDKEANDKAMDGVRADKLREARAGHDGTWVAHPALAGIASDVFNTHMPTANQLFVRREDVKITRNDLLNMNVPGNVTESGIRKNLVIGLGYMEAWVRGVGCVPINYLMEDAATAEVSRSQLWQWVRHGIKTAEGKTVDKAYALKLLKETTEELAAKAPTGNKFQLAAQYFANQVTGEDYADFLTSLLYNEITTVGPASPASKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIB9</accession>
    <name>A0ABR3YIB9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_006490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000309">
        <property type="protein sequence ID" value="KAL1887587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1887587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="99" mass="11242" checksum="9FDF489897B4C7DC" modified="2025-10-08" version="1">MPKDVSDERVQSRVHQVLHKQGDNLVITAAIWAKNPDFDSVGTTTTGHETLLSPFVNEELSAFWNTALQNNGRYWQARSAVKDKARMFSNDWGLPWQIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK88</accession>
    <name>A0ABR3YK88_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000269">
        <property type="protein sequence ID" value="KAL1888253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="278"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="464"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="238"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="255"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="320"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="492" mass="50913" checksum="6D43D379CB83FE5D" modified="2025-10-08" version="1">MIALAQASASVLPPRQPTITNKPELAVRKIDARSLPESILAPHAGALHKRFNVVCGYIDGNPLMPAVCNPGSHCAVDKALGAVGCCPDEGPCDTGIFTGCVDMTGPPPEKVDPLVYVCGAGQVCYKNNYEGGYSQFGCGTPGSPPATVLVNVAGQPPIDIQQVNIKANPTSDGGAGAGVPAPAQTTTSESNSQSKSPEPVATPKQLLSSSSSSSSSSALSTTPTPATPYPTGSRGPQTLKTTTTSTTAEEAYGMASEATVTATTEAPKTDKDTNHADVGAVVGSTLSGIAAFLALGAVGFYYYRKKKQTQSPTPPPNEKSMSSPTSSHGSFMTSSSQADNSPTSMTEPMFLVDHDFPLPPVGAAVSSNHKQNYGHDGGYPMDIKTDFDHPNNIQPTVITTATAGGPGAKSAKDNTMSYASSTYSRYLQPGALPSPTSPYSDSGLDLAREVDDFQNSYIAALGDIREESESSYSRNSVPPVPPMPQKPDSAWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKH0</accession>
    <name>A0ABR3YKH0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Eukaryotic translation initiation factor 4E type 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_006031</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the eukaryotic initiation factor 4E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000243">
        <property type="protein sequence ID" value="KAL1888804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.760.10">
        <property type="entry name" value="RNA Cap, Translation Initiation Factor Eif4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023398">
        <property type="entry name" value="TIF_eIF4e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001040">
        <property type="entry name" value="TIF_eIF_4E"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960:SF66">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01652">
        <property type="entry name" value="IF4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55418">
        <property type="entry name" value="eIF4e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0810">Translation regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="249" mass="28627" checksum="8BD4FDDB2B3BE923" modified="2025-10-08" version="1">MSTRPPFPFARTSGLSQATTADSISSPSGERDDAKRNFLKAMRPLPTQHYWDVYFNRTLKDQTPNGDEYQDQLEQLCSQIDSVQEFWKYHNNFPVDQIKMRESIYLFKQGFKPIWEDRRNIHGGSWTFRVPKSQSIDIWTRVQLLAIGEKLESVLEEGDQLCGVGLSVRFNSHLITVWHRDASKKKSIENLLKCVLDEFPEDKQPKADTFFYKKHSDHSGFKATPEIQAVLDSKKRNEEAAAAAAAAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL51</accession>
    <name>A0ABR3YL51_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000252">
        <property type="protein sequence ID" value="KAL1888612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054208">
        <property type="entry name" value="DUF6914"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21858">
        <property type="entry name" value="DUF6914"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="209" mass="23659" checksum="201B0D93A144ACE4" modified="2025-10-08" version="1">MSWIIEKFFRGEPRHWLYVCVYDTGFIAESTTDSRYHWALIIGPNSQNTVLSGTKHHICKALPSSSEWSLEQVGLKDARFDFNLIVRVAVAEVTDPTYLDKTLATSSESWMCEAMNRINKGMTGVRCLKRRTKKWWEIKEITLAEANQVIAEGGFSTDNVSQSASPLRIHINGHSEEKARRKEAVRLKRQATRESGLSRNTQGAAPSVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL56</accession>
    <name>A0ABR3YL56_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Anaphase-promoting complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_006108</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the cullin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000253">
        <property type="protein sequence ID" value="KAL1888607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1310.10">
        <property type="entry name" value="Cullin Repeats"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.130">
        <property type="entry name" value="Cullin, Chain C, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044554">
        <property type="entry name" value="ANAPC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014786">
        <property type="entry name" value="ANAPC2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059120">
        <property type="entry name" value="Cullin-like_AB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016158">
        <property type="entry name" value="Cullin_homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036317">
        <property type="entry name" value="Cullin_homology_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057975">
        <property type="entry name" value="TPR_ANAPC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45957">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45957:SF1">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08672">
        <property type="entry name" value="ANAPC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26557">
        <property type="entry name" value="Cullin_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25773">
        <property type="entry name" value="TPR_ANAPC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01013">
        <property type="entry name" value="APC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00182">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75632">
        <property type="entry name" value="Cullin homology domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50069">
        <property type="entry name" value="CULLIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Cullin family profile" evidence="8">
        <location>
            <begin position="508"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="734"/>
            <end position="766"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00016068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1888607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="836" mass="94481" checksum="0B90BD89DA27FF40" modified="2025-10-08" version="1">MSQAWALQRHVIFNSIFPSDALRANETVLPLRTSPRKQSGSVVHGDSVAADQRRWSVAWHHVTDLLKLPDGLANRNDISSGDGFDAALCIILNPEREVPHATKKDDLIAWYTKQMYYHYTQSVKPALDLDLSQRDDEAYFSDAINTLETAAQLYLLRAEPIFKGMDEIRAHEARMRFLREIHGLIASSQTEYFHEVMVSLLKCHTHAVLLGEDNTRLDDRVRFLALIDSLQSIGLTDRRFEVTFAEAMNEALKAHIEMAYNNIFTQQLDVGHVFGANNTAWNNRKVVVSQNISTLYSWIEDTFSSLAVEVMSKLGRPITPSHVAAWKENALCILANLRSSQLYDIVLHWPDSRGGLLDLKSCVTTTSQRSRLTSVFSRNLERRLLHPGSSTLHILQVYISIIRTFHALDSSKVLLDRVVPSLQLYLCQRVDAIRIVVMGMLSNHQDVGTEASKGKLSELAAILNSTSQAKRPALDDEDQDWNDMDWNPAPIDAAANFKRPRSEDIIGTLISALGSQEMFIKEFHVIVAERLLSVSSDLQQEVKVLNLLKRRYGDTALQHCDVMLRDIIESKKLDDLVTSAVKGTDQSRDRCTLPKCSAKILSRLYWPNIEREHFLIPECVGQAQRQYSENYRHIKSSRKLTWLDHVGTATVELELESCTVAVECKTYVATVIYAFGDESQDSYRAEDRRPIKLTVDDLEIKLQMDTDYIEEALAFWVKHKVLRQVSDGAYVVTEREEGSTGGQPVDSSVEDGGISDGSKKPSSAHSEKGPIYWQFIVGMLTNSPTAMPLPRMTMMMRMLIPGGFAWTDEQFQEFMAEKVEADEAELVGGKYRLVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM72</accession>
    <name>A0ABR3YM72_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005858</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000223">
        <property type="protein sequence ID" value="KAL1889292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23703">
        <property type="entry name" value="mS26_PET12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058940">
        <property type="entry name" value="mS26_fungi"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26163">
        <property type="entry name" value="mS26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="310" mass="35436" checksum="9FFC990AAA329DF5" modified="2025-10-08" version="1">MASQTSMVSLRLIRLRATTPFTTAQRAFVTSSSVRQTDKPPPESPAFIYVPTPPLSETEKLPRVRGHLPIPRNVFPPAEGDRKVTESYIQQTAPEPSNESSTIPVRDGSAEEWRRKMAEKRRENLRQGLSGLWQRKNARDDEEEKAKTRKIKRDKKASEAQEPRSEEYTRSTVLKATAEDTAVLPDPLRMQRAEESRIRTSEIQAQHRDARRDHLVDLYMKASKFIVHETQLQQEIDRIFSETYWPVQPGFYEDGNAWASWGNPPSVENMLNDYTNSGNTRQFTSSRAGSTHNAMRQKEVAQELIGGKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMH8</accession>
    <name>A0ABR3YMH8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">NADH-cytochrome b5 reductase</fullName>
            <ecNumber evidence="14">1.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">CBR1</name>
        <name evidence="16" type="ORF">Cpir12675_005763</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">NADH-dependent reductase for DPH3 and cytochrome b5. Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase, predominantly CBR1. By reducing DPH3, also involved in the formation of the tRNA wobble base modification mcm5s 2U (5-methoxycarbonylmethyl-2-thiouridine), mediated by the elongator complex. The cytochrome b5/NADH cytochrome b5 reductase electron transfer system supports the catalytic activity of several sterol biosynthetic enzymes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2 Fe(3+)-[Dph3] + NADH = 2 Fe(2+)-[Dph3] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:71231"/>
            <dbReference type="Rhea" id="RHEA-COMP:18002"/>
            <dbReference type="Rhea" id="RHEA-COMP:18003"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83228"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:71232"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>2 Fe(III)-[cytochrome b5] + NADH = 2 Fe(II)-[cytochrome b5] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46680"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Monomer. Component of the 2-(3-amino-3-carboxypropyl)histidine synthase complex composed of DPH1, DPH2, DPH3 and a NADH-dependent reductase, predominantly CBR1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion outer membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.2.2" evidence="14"/>
    <dbReference type="EMBL" id="JAWDJO010000214">
        <property type="protein sequence ID" value="KAL1889523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090524">
        <property type="term" value="F:cytochrome-b5 reductase activity, acting on NADH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF184">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0274">FAD</keyword>
    <keyword evidence="5 14" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="9 14" id="KW-0520">NAD</keyword>
    <keyword evidence="8 14 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="15">
        <location>
            <begin position="60"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1889523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="309" mass="34007" checksum="FE92E9E11AE27A87" modified="2025-10-08" version="1">MPESLTSRKYFDGVYIPMGLIVVGVYIIKKEWIPYAIALAVALGSYKFNSMQPKKVLKPDQFQEFELKEKTIISHNVAIYRFALPEPNSILGLPIGQHISIGANLPQEDGSSKEIVRSYTPISGDELPGYIDLLIKSYPTGNISKHMASLAVGQAIRVRGPKGAFVYTPNMVSHFGMIAGGTGITPMLQIIKAISRGREMGDTTEVDLIFANVTQQDILLKEDLDELVAADKRIRVHYVLDRPPEGWTGGVGYVTPDMMEKLLPKPAKDCKLLLCGPPPMTSGCKKAALGLGWEKARPVSKLQDQIFCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMW3</accession>
    <name>A0ABR3YMW3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ATP-binding cassette transporter snq2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SNQ2</name>
        <name evidence="12" type="ORF">Cpir12675_005693</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000208">
        <property type="protein sequence ID" value="KAL1889689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03233">
        <property type="entry name" value="ABCG_PDR_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029481">
        <property type="entry name" value="ABC_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034001">
        <property type="entry name" value="ABCG_PDR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010929">
        <property type="entry name" value="PDR_CDR_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14510">
        <property type="entry name" value="ABC_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06422">
        <property type="entry name" value="PDR_CDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="501"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="534"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="576"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="610"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="643"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="671"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="749"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1196"/>
            <end position="1215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1236"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1275"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1308"/>
            <end position="1327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1428"/>
            <end position="1449"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="144"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="827"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1889689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1454" mass="161223" checksum="7741A778C99DF386" modified="2025-10-08" version="1">MGAPVAGSDSSTSNSMNDPGNRREEADNSPYDPSGSRGGVSVQAAEAEFAELRKSMSRASRASRSKQTHEDPEKASDSADDGLFDLESVLRGDIAREEQAGIKPKHIGAYWNNLTVSGVASSSNFIFTFPLAMLLQLDVVSPVRNLMGLTKKPAETRILDNFSGLCKPGEMVLVLGRPGSGCSTFLKTIANQRGGFNGVEGDVRYGRFTAEEFQQYRGEAVYNQEDDIHHATLTVGQTLDFALDTKVPGKLPAGLTKNDFKTNVVTTLLKMFNIEHTRNTVVGDAYVRGVSGGERKRVSIAEMMITNACICSWDNSTRGLDASTALDFAKSLRVMTNLYKCTTFVSLYQASENIYNVFDKVLVIDSGREAYFGPIENARQYFEGLGFAPRPRQTTPDYVTGCTDEFEREYAPGFSKENAPHSPETLAEAFSKSDVKKALDREMEEYLQNLNTESAKFQNFQVAVAESKRSSPSHSVYTAGFHIQIWALMKRQFLLKMQDTFSLYFSWFRAIVMALVLGTLYYDLGSTSADAFSRGGVLFISLLFIAFQTFSELASTMTGRGIMNKHRSYTFHRPSALWLAQIIVDQAFSASQIFVFSMIVYFMTNLARDAGAFFIFYLVLVIASIAMTLYFRIVGCLSPDFDYAMKFTVLTLSALIITSGFLIAYPAQHKWMRWLFWINPVGLVFASMMINEFMRINLTCDGSSLVPNGDGYTEIVNQVCTLPGSVAGSTSVRGIDYIEASFGMSKSDLWRNIGIVLALIVLFLFLNVTLGEMVNHSGPGGGAKVFDKPNQEREALNTALKEKLEARRANPSAEQTAELSFQSEAVLTWENLNYDVPVPEGTRRLLNNIHGYVRPGELTALMGASGAGKTTLLDVLAARKNIGVIAGDVLVDGAKPGLEFQRSTSYAEQIDLHDPTQTVREALRFSADLRQPFETPQAEKYAYVEEIISLLEMEHIADAMIGFGDFGLTVEQRKRVTIGVELAAKPDLLLFLDEPTSGLDSQSAFNIVRFLKKLASAGQAILCTIHQPNASLFENFDRLLLLQRGGRTVYFGPIGKDAHVLRGYLHDHGADAAPTENVAEFMLEAIGAGSRPRVGPTDWADIWDNSPEFAQVKETITELKREGAVRSTNSTKGPDQEYASPFGHQLKVVLNRMNISFWRSPNYLVTRILNHIFVGVIAGLAYLNLDNSRTSLQNQVFVMFQVTVLPALIITQVEVMYHVKRALFFRESSSKMYNSIVFAMSIVIAEIPYTVLCAVVFYIPIYYMPGFEGGSSRAGYQFLMILITEFFSITLGQMLGSLTPSPFISAQFDPLIMLILSLFCGVTISSSQMPDFWSSWMYELDPFTRLISGMVTTALHGQRVECTNSELNFFNPPNGQTCGSYMDNFFAAGGAGYITNPNSTECGYCAYVVGDQFYEPLDLNFDNRWRDMGIFLAFVGSNLIILFLGSRFINYNKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMY7</accession>
    <name>A0ABR3YMY7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005874</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000225">
        <property type="protein sequence ID" value="KAL1889228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="134"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="243"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="307"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="356"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="410"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="522"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="578"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="732"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="790"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="959"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1091"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1152"/>
            <end position="1202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1277"/>
            <end position="1335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1374"/>
            <end position="1452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1500"/>
            <end position="1625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1725"/>
            <end position="1792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1811"/>
            <end position="1833"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1638"/>
            <end position="1672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="16"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="40"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="134"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="278"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="441"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="463"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="543"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="578"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="801"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="868"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="959"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="985"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1092"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1152"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1170"/>
            <end position="1180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1295"/>
            <end position="1304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1394"/>
            <end position="1405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1424"/>
            <end position="1446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1513"/>
            <end position="1524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1533"/>
            <end position="1542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1558"/>
            <end position="1575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1577"/>
            <end position="1596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1726"/>
            <end position="1756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1816"/>
            <end position="1833"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1971" mass="216513" checksum="D7BD413C3F44BCBB" modified="2025-10-08" version="1">MAVADDHQSDRLSSPDPLNSESDYPQSTTPARRAFRSNRKNTTTADSARNLARSQSPTSQSTAVRTRLSTYRVTPRTRTIAQRSVRDSATAPSPRKQTFELEVGHDISPQRLLVTVEAGDFDFSASGLHRRLFASSTPPSQASPSRMATPLARSTRRVPLKGEDEVSTRIAGTPRRPRASSNSSRRETPGATPTDTPRRTQTAHHRSVTPGHQASATPMRRSTRKTKSLMSNTVMISDLASTTPNSAFDLGETPIPAVPKEISKPKPTTARRSTRTRNTPEKEPSVPDIHDGFDLDDVLLFPVLATKSRPDVPSHPTPADSGASATSGEPTTTVNVVTTTIPIADTPQISRREFKRSRSNGEDYFDTPATKRRFTPRRPTPARLGPTNSSSNGVPATESFADLFLDSTPDRSVSPSAHRNESLGLFKMPTVPETSSVQKNGQAAAGAAPDNDGDLWLDNLSDDETRFRSASRDAETANRPLQPTSIVPSVETEHQTELYTNDHSAYGTRGVSEAKAYEELATPNTEPLRDEQEQEDTDQSQQNHDEHSTQQKEDSRNSHEPETHLEYIQDGPKSLLNYRNSPFISPSQAHHNHNPAELSLVPGSSRLAPLRIESEAPSEPMSEAMSASSHMRHDEDFSMIFPDSLHIDTSLPLGSRNDFGDTTNLAINRTLESLRRDRENGENSQLNSSLATPVHLETVAEEPEEENRVQDLPRLSSPLIRFGNSPLLRSATKNAAAAHNSTSPMLGRALTPRQRKPPSLSQQLLTREALKAEQTPAGKIVDKAKSLGTLLSSGARRKPRQSLQSQQPEYEDSFTQPSGSFLAAMAPKTGDYDHLSQEESTTPDTVQRHDVIDLGSDGETPRKPLESSKVSSTPAENNQTKSLGAVVTPETRRSDEIQTTGVDTRKPYGAPPRISISTVPTMDKNIGAIAAPSSPAPSTVQPIERPLLSSAVRAGWALQTVTSEKSSPMNQNGLGSPFRGGDSSPLANRKSSNNHTLEVPAPNPPPLFGGPTRSSVPPDSLPSIPEPTSPVTYEQEDSIFKTVPATQPTTSFRRPGRVHHAASLSPLGESTAATAPVVPVLAAEEEHIADVSWTTDPSRSVLQNTAPPRPDSQALRKENMLLVKAASNSERKGDEDDDDDLWAIEADRLLAGNSTGTHTPTAQKGVNKRTLPDVENKEVEFLQLPPNKKSKKNDEIQPKADSILPQPRLASINKATTVTAPRQNGARMHMQGLDASKYRGSSRFRPMIGRHRGIVSQNGSGESPEVSSKTAFFQRKLEQAHREAAAKAGQKQKQSLQMGTSSPATPAILSKDGNEQRSVFDPGPGAGSGPGSGRIDLSTFFSSPLSLPFQSARKAATAVAAAASRRFYPGTTATIDMQDEADSNNVMYGDSRESNSSVLPTSSMFPSLPPRQPGTRTRNIHRYQPQSQSQSQPPSRVVEVSRSSSPIAAEADDEPEDTFFNHSMAHTIDQSHLNDYEEEEDHEATDDEVESDHSVVDIADAQLAKGDDDNGNIHSDAAIASIASMDEDDNAEDQNSSQSDPQEPQDEPMTPSRRLAVTTPQNAHTPPQMQLSCNDISRWREETSKVMEESPKEMRPLPRPGFPHHRALSPPKSCMRSPLKGRTPGRVVEFTSSTLSPLEQQRQRLQRQRSLAVDEQNRLEEEQREAEALANFERQVLEGARREREVSVVSGMSEPSPKLRHRVGIVPPVTLAPPASGFVHQPIEMDVGEDTDPDYEYEDDNDDDEDEDVESEEEEARENQPQPDDREVMDTPGVEQGKHAHRTSRLADLFTPKQTLAERQRAATASYHYLEPQAPPSDLSSSPSAASNASSAPTIVLPRRMHLSRRTWTNSHWRHLKYLVRIRRTRLFYFNARYVRPSEQARLVGETVSGAGESMRIMQEHADAIDAFMGDVPGWDVRDVAKRVFALVKADELRQREWLNQQNHRYHDNQSQNQHQNGEGSSWWRNWVPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN47</accession>
    <name>A0ABR3YN47_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7029 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_005704</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000209">
        <property type="protein sequence ID" value="KAL1889623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054293">
        <property type="entry name" value="DUF7029"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22974">
        <property type="entry name" value="DUF7029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046224440" description="DUF7029 domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7029" evidence="3">
        <location>
            <begin position="155"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="524"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="760"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="528"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="803"/>
            <end position="814"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="843" mass="92790" checksum="924702BD2EFEEC64" modified="2025-10-08" version="1">MPNLRRLVLVALGLPLGLVGAVPMLPPEDNISPGLPSIDGPALGLVPDVASNLPPPSFSNHIGNPTTTDAPEVDDDFLDLDPQHTYLTTTTTFMRLSSPVSQVVIEPTDVAESVINTYIPKNAETYLNAMTPSLDVKVLYASLDAEDDGEIEIALKMEIPTVVLEAIEDVDRVSCDSENMYVTFKNWQMYEKVLEEWQKARDLVVISNHGGKCDDDNQRGFYEVISITGNPKLSTVKISVYKAQISEVVRSFTMGFESVPAGEIRRRFIAWKGDVWSASSDDTLGPSRKLASMAITKTLDLENTIYEDEGYINIVANEAHFSAGITFSGKLSYSFLTLKLEQLYMDIDVSFDARLNLTADVRRQFSYMMEYSPAELFFSMVNVPGILEIGPGVRFSIGTEVKTGAAVNMTTDFAFKVPEGKIHLDFLNRAKTYATGWSNPEYHSSSSISERLNAELTPSVGLAIELSANLFYGLINLSTGIKITPQIVNSFEVLSSPEELEDIKRIKGGVATPSTKDIVPYKNGNKPNKLRKTKSNKGGRRAKAKKRKQSTVNAMVPHNADGSVVKAPQPLYDCGADLSNGVALKSSLVFQMVAHVAELWAVNILEMERPMIERCWSMPVFQVSKSNGFDMFEDDVEELKKIAQAGKGDDLFSALDDDIYEPKSLAKGGKGDDLFSALDDDIYKPNSLAKGGKGDDLFSVMDDDFDSETDNDMDDDLDDNLYDNLYDDADDLEKGEKTSKNNMFHLLDGLREGNMDKLKKGGKSGKYKNMPSNLDGLTQGGKAGKDNMSGSPDNVPDNVPDNGELDDEMFDASDEELDDEMFDALDEELDDEMFDADSDSASW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPB2</accession>
    <name>A0ABR3YPB2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005649</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000204">
        <property type="protein sequence ID" value="KAL1889784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="505"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="649"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="768"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="910"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1079"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="164"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="512"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="531"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="582"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="658"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="670"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="925"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1122"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1166"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1566" mass="167824" checksum="CA56B6462CA703C1" modified="2025-10-08" version="1" fragment="single">QNIIRSPYSTNASPFPSFIPFLVPSYTTAEMSSASMRKGASAAHLQSFPLTPSPDALESTPNPHAADKALSEPVASAAASAISSTITAPPASAPPSTTITAIPNHGMPSKKDSAAARKKVLSVSLAISDRPSVSSIIERLETRTQQEIEEQNRLDQLHLERLAAEASASTSASATPKPSIPGHTTSSETLIQKDIYQDQSQSQVHGENEKNRNATAESIPTSSSSSHLLISPEPDMPTTALIEMQNTRGGGSGGGAAPIPPGVGAGPAIATTVATTTGIAAARVPSSAPPSYSGQPLLQDHFSSISLGSLDLGLNFEASSEYSATNFNTLNLQAQQSSKLPLPRPKPDALGSQTRKQPQQPPPPSSSSSASVIQQLQNQIQDLAQAGKPFDPPPPLVRTTSHNGALPIRHPVPDVPPRSITTRENIAQLEATAVRLSMTSSIDDAIHNLHSELKRSDSRRSSILAASLKEREREEEARSLPALSRHISNASSIVSVNHVARLGGYSPGEYPVTSSTAESITTRLRAKSDTDPSASLANLSRSGPGKSSIRSIHSRPLAGIVETERDTPARNRPNSRMEPLSEQDQQQPRSSFQTKGQTASPSHSRKASSINHLMRMPSFEASTAETLSLGFDAQGAASNRRRLSSIAQNNSETETEPQTQGQHSQAQSQNTHNNTENPQVQSTPRQKNHHSQKDSTASTPESERAKDVFGDFDGVHCDPDVDLHNDRHEIIHSLSDFNLLNLSDTLGFNVAPSGNTLQDQQYLDQNQPYAENGSVPHPGQDLTANYAQSGEPVPSKLPQNGMRQSMAMAMPPVRPQSYMDPGTGMEMAFYPARVPMMLNLPQKLSKKPKAAQRNARQSKVLSMMPNINRQSAPWLNNSSHPEGEQLYYEQFSAKPIDFLGDPLAGTHDTCSMASLDGNGNIDGPGQSQQDTGTPHNNPVSPNPTFQTGSDSTEHANNGLRSVGQDSLANRDTIYNSGPLPMPVPAGRQNNRASHLPPQLRASVFFEMPSTTTDIKIEAGSATHTLDKLLDASATAPVSAFTDHLLVGKLGVDGQGRPNRRSMAPLSDKRQSHNLYNSVSVEGLRKPTKLKKRASQMSMGIPSVNGPAGSAPSGATQAVRSSRRLDLDVSDNDSHHDTDLNDGANAMRPDDDELDQTHMTNVSFGGDEQDGDDEEEQEEEEGEEMYYGPPTTLLAELQIRKQQQKLRTRGHFPNGMHSTLLELDAVAERQRQNRVKGKVNLAWEEGADGAGNEESDEDVPLGLLYATKATGTKNLNLAVAEMNRPLGLMERRDMEDNEPLSSRRARIMGDQYTPVRNHTMVSRAAPTGLGNYAVPESEEEDEPLAARRARLKKEESCGALPSTRPVSRAFSNELLTQFAAPEEETTSKTPAIEAEETLGQRRRRLQAELEAAAATAKPAASLSPGIQKAGGLANLLAAHPTANANPLYSGAFSASKGNLGFKNGVYNTGRVGIRPSSSQVHLQSPHGTGFQARQHNLATSASMGQLTPAYHQQAPLMGGGGGGGGGYPQGAYAQPMYGHGQQTYGGYGMPVNKQVDRVEQWRQSVMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPE1</accession>
    <name>A0ABR3YPE1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">trimethyllysine dioxygenase</fullName>
            <ecNumber evidence="5">1.14.11.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Epsilon-trimethyllysine 2-oxoglutarate dioxygenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">TML hydroxylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">TML-alpha-ketoglutarate dioxygenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Cpir12675_005515</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Converts trimethyllysine (TML) into hydroxytrimethyllysine (HTML).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>N(6),N(6),N(6)-trimethyl-L-lysine + 2-oxoglutarate + O2 = (3S)-3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + succinate + CO2</text>
            <dbReference type="Rhea" id="RHEA:14181"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:58100"/>
            <dbReference type="ChEBI" id="CHEBI:141499"/>
            <dbReference type="EC" id="1.14.11.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amine and polyamine biosynthesis; carnitine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the gamma-BBH/TMLD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.8" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000192">
        <property type="protein sequence ID" value="KAL1890176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00250">
        <property type="entry name" value="CAS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2020.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050411">
        <property type="entry name" value="AlphaKG_dependent_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010376">
        <property type="entry name" value="GBBH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038492">
        <property type="entry name" value="GBBH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012776">
        <property type="entry name" value="Trimethyllysine_dOase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02410">
        <property type="entry name" value="carnitine_TMLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696">
        <property type="entry name" value="GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696:SF51">
        <property type="entry name" value="TRIMETHYLLYSINE DIOXYGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06155">
        <property type="entry name" value="GBBH-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0124">Carnitine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma-butyrobetaine hydroxylase-like N-terminal" evidence="17">
        <location>
            <begin position="82"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="TauD/TfdA-like" evidence="16">
        <location>
            <begin position="166"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00046008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF06155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1890176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="449" mass="50390" checksum="B16BEA1DB275F9A0" modified="2025-10-08" version="1">MAHITAIFGQASRVFRISRFAAVYGHHVIGLEPAAALATSKRAYSSFVGCKGTNVSPGSSKIVWLTPGSIVVEDGADQGPIKRSSLPNFWLRDNCRCSQCVNPSTSQRNFDTFAIPKDVTPSQVESGANGLKVKWNHDGHESFYSWEFLSFYKNNDARTAEPLDLQLWGAEIASKPPSVTFEEVMSKDSDDSGVAKMTRLIRVYGMVFIEGTPHDSPAATESLLRRIAFIRETHYGGFYDFIPDMAMADTAYTNIRLPAHTDTTYFSDPAGLQSFHILSHTGKDAKGGSSLLVDGFKAAAALKQESPEAYTILQKVRLPWHASGNKGITISPDQRYPVLETGSEGELLRVRWNNDDRGVVPFEDGIDPVQWYEAARRWYEIVNRQDIEYWRLLKPGTTLIFDNWRVMHGRSEFNGIRRVCGGYVNRDDFISRWRNTNYPRAEILDRIVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ82</accession>
    <name>A0ABR3YQ82_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000188">
        <property type="protein sequence ID" value="KAL1890267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37848">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37848:SF1">
        <property type="entry name" value="SUN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="479" mass="54694" checksum="F44D8BE0E2452349" modified="2025-10-08" version="1">MGSDDKHRGSPITDGTFSQSHSDGPVGGPSEPPPAFDDAIFSQPAMSGSGPVFIPTSSPAPTESPPQYAEIINADHPQPENNLLVPANPPFVRPLAKHLKWFSSDCYLDPQLDSDPAFLETWIRHVAREPIQMQLRISGQHTETRMNMHRDSDGRSRSRDHQETVEDFDFQIDLTAFLFCDMLSKASWTELRTVENHEKAYRGGIFRSRAHPFRDVKKLWRRRQRLWKGRRRDLTIADEESESAAILRPEAASGVSLGSNNNDSLDTLENSGLTLGGEEKPSLTEWCHRYCSSGLVRSFEVEKRVLGFDESYVRGRVTNLIRTTGYMGDVSITFPVDHARMTVFSSCYINEWRLMKWLRWAVILTLLVVLVWPYLFLRTRKFNVVSVNWWFSRRDEATGDRRFVSMSEDQILDFWQHGIQEAAMRKRRGNLHVGDAVSARDSHSRGQGAEAYRDVQGRMESAFYAASAMQRHTGWGWHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQD4</accession>
    <name>A0ABR3YQD4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">Eukaryotic translation initiation factor 2A</fullName>
            <shortName evidence="8">eIF-2A</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_005325</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the WD repeat EIF2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000179">
        <property type="protein sequence ID" value="KAL1890573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011387">
        <property type="entry name" value="TIF2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013979">
        <property type="entry name" value="TIF_beta_prop-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13227">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13227:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08662">
        <property type="entry name" value="eIF2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017222">
        <property type="entry name" value="eIF2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 8" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Translation initiation factor beta propellor-like" evidence="10">
        <location>
            <begin position="212"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="419"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="468"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="431"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="526"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="575"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR017222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1890573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="681" mass="74138" checksum="9E2C2F2189E69637" modified="2025-10-08" version="1">MAPLQFAYRTQKTVNVFDASPKYQQNSGFTKYEGTSRCCAYSPCSRFFAWSSNEIVSVHDTSSGKVVFVLPIPTVIELGFSPKGTFLITLERPGKDEAGDATKNLKIWRTAVEDDKQQPIGRFVQKSHSEFNLQYTDDEKYCARLVTNEVQFYLSGDLSSVSQKLRVEGVSQFALSPGASHSIAVFVPERKGQPAAVKVYNIPMFSSPVSQKTFFKSDKVKLSWNKNGSGILVLAQTEVDKTNKSYYGESTLYLLSSTGGYEGRVSLDKEGPIHHFDWSPNSKEFGVVYGFMPAKAKIFNSRAVATHEFPTCPRNEIFFSPDGRFAIVAGLGNLAGQVDVYDLGKDYRKLCTIESGNPSVLEWSPDSRYIMTATLSPRLRVDNGVKLWHVTGPLMYNEDMTELLQISWKPVAPQDLLGSDPTNPVPVPHASATSFLSTRKTPSKPAGAYRPPGARGMAAPLHFKREDEGGSSHVINAGISQTSGGTALNGFGRPRRAVPGAEFAEPAPRTVPGSEPVDENLSKNALKNKKKRSKKAKENESKFPEPNGGVSLAPPNANGGAYGNGGRSPERRNGQNHSTARSRSRNPNGGRARSSTTRSHGASGAINGSTVPDMPTAVNGATAEGDAQNPATKNIRSLRKKLRAIEELEMRLARGEKLEDTQMKKIGTKEVVMTELSALGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQW6</accession>
    <name>A0ABR3YQW6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nab2-like CCCH zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_005289</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ZC3H14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000176">
        <property type="protein sequence ID" value="KAL1890688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.40">
        <property type="entry name" value="Nuclear abundant poly(A) RNA-bind protein 2, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055046">
        <property type="entry name" value="Nab2-like_Znf-CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040366">
        <property type="entry name" value="Nab2/ZC3H14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043094">
        <property type="entry name" value="Nab2/ZC3H14_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14738">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14738:SF29">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22683">
        <property type="entry name" value="Nab2-like_zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14608">
        <property type="entry name" value="zf-CCCH_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Nab2-like CCCH zinc finger" evidence="9">
        <location>
            <begin position="474"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="295"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="144"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="300"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF22683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="542" mass="58393" checksum="A0B0B8AFDE43C503" modified="2025-10-08" version="1">MPIEVQPNTPLADALNAVVQPKLEEIGWGSGDPDDTSLAEYIVLMLVNGRSQDEIAVEISQELLGQSTDDPVAREFSQWLFAEVEAQNARLNGGNANGNGGVANAASATASDQGVFGNQQAENMPIIDADSMDMSGDMAQMNVPTGPRSMRNGNGNGNTNNRGRDRRIFNQMNKNMDRTIDGGIHRVQRGTGNERINRGSNGMNMGMGTRNNHNNMRGGRNNMNNRSAGVQAGLNAAAMGQNIVNLPHGMNNNWGAPMGGHPMGGAPGQQQPSQMDLFALLEQQNRMMAQLSQQMMHSNRGGGRGGRGGGGRGDHNSRRGNYGNHTWTPGGGAAKTDRSENGDAMQTEAADGEDTDMTAKRESVNPEDSMCKFNLRCTNKDCKFAHQSPAAPPGTTVDIKDICSFGAACKNWKCAGRHPSPAARLAHQSVQDCKFFPNCHNQHCPFKHPSMPLCINGADCLTPDCKFTHVKTKCKFTPCLNPKCAFVHDEGQQGNFKDKVWTPAGGANGNGAEESTEHVSERKFVIDQEEPEHIKPEDVDIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR26</accession>
    <name>A0ABR3YR26_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_005255</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000173">
        <property type="protein sequence ID" value="KAL1890800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15486">
        <property type="entry name" value="ZIP_Sip4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF25">
        <property type="entry name" value="ABC-TRANSPORTER-REGULATING TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="79"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="167"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="769"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="874"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="192"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="244"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="783"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="796"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="809"/>
            <end position="831"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1890800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="986" mass="107640" checksum="20F15598EB123206" modified="2025-10-08" version="1">MDPRASFQMPPLVNSPPCIFGGYSPVDGISGPGPGPDGSTGSAAAAFGVDLAAVTAGMFGDAALLDDLNESKRRRIARACDMCRKKKIKCDGKLPCCTHCVNYKTDCVFTQVEKKRSPPKGAKYVEGLENRLGRMENLLRLSGLLDDGDGATDLAILEKKLAEKQQSKKLQDGTGAAAASSPSLPDHKAAYMSTTTQSESHTVAHESPADSSTAATTATATCSTNSGSPAEDSKIRPTSPDADGQSKERDPGGHPHEEVEALSEMMCSLVSNQSGETRYIGSSSGFSIFSPKGIEWVNQKTGDNSFQRMITDVSIDDHKWTAWKPEVFGDLFPRPIFRALPNKADAMSLFKDYFENFNCMFPLFHQPTFMHLVERHYSGDPHQGSGWWASINVVLAIANRLRVMSNLVPADNDCIAWDYLKNAMAVLSELVMRNADLLSVQALLGMALFMQGTPNPQPSTLLIAMAIRLSHSIGLHKRGTGFNLNPIEIEQRKRVFWIAYMLDKDLSLRSGRPPAQDDDDMNVELPDADPADNIGNIPLADGVSKMNLFRLMCEFACIESKVYKKLYATKATKQSDGEYLNVIGKLDKELEDWKNSIPIDFRPEYEIKASHTPLILHVVMLHFSYYNCLTTIHRMSIHHGYWTSRLSNYAIQGLNSKPINPRIFSSAALCTSAARASISLIKYVPQGDNSCVWMILYFPVSALVTLFGNILQNPLDPKAKSDCRLMNMVVTFLSMLGHEAETGGVHRMLGVCSEFERIAKLVIENAEKGHVSRRKRKSHDGSARSGPSSGARQPFPSGQTSFMSPLQSQPMPHQPYNQQPQQQPQPQQQQQNFKYPHSNRQSLTPDMAYAAQQATSGNFMDAISPMSGGWQRDFCLTPDSASSGGGGGSASGANTEFTASMGASIGGSGNTQSESPSMGTIDGGAAMRADFQFQMPAQLFAQQHQQPLIPQDLYSLPISLDWAWAEMSGGAYPTVENGNFHGMGGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRK6</accession>
    <name>A0ABR3YRK6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005344</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000180">
        <property type="protein sequence ID" value="KAL1890562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046368">
        <property type="entry name" value="Tag1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895:SF3">
        <property type="entry name" value="PRE-RRNA PROCESSING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26174">
        <property type="entry name" value="LEA-2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="289" mass="30641" checksum="5291294C8C7B2259" modified="2025-10-08" version="1">MTSPPSPIGSALGQDPGPSKTPSANPIFDDDDDHIPSDEVSPLLGATIPRRYDGAASGSQEPSDDSNDSSKLASTKVSRKSLASTVAIALLGLVSLLAIVGVFVLPHNVESYVKQAAVLEPTNLAIESVTSDGIRARIGATFKLDSRRVTEDTPRKVGTFATWAVRKLATAETRLHLYYADSTNTDLDNKLLGSLVVPPLAINLVDGRVTHLDFITDIVPGDAEVFRSLANQWLHGQMGAIKVIGKANVTVKTGAIPLGTHAVAESLSIEGQSLYHSFASTYFGEKRLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS52</accession>
    <name>A0ABR3YS52_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">R3H domain-containing protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_005221</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000170">
        <property type="protein sequence ID" value="KAL1890825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02642">
        <property type="entry name" value="R3H_encore_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="entry name" value="R3H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001374">
        <property type="entry name" value="R3H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051937">
        <property type="entry name" value="R3H_domain_containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024771">
        <property type="entry name" value="SUZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15672">
        <property type="entry name" value="CAMP-REGULATED PHOSPHOPROTEIN 21 RELATED R3H DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15672:SF8">
        <property type="entry name" value="PROTEIN ENCORE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01424">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12752">
        <property type="entry name" value="SUZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="R3H domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51061">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51673">
        <property type="entry name" value="SUZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="R3H" evidence="3">
        <location>
            <begin position="248"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="SUZ" evidence="4">
        <location>
            <begin position="314"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="27"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="92"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="344"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="487"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="631"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="727"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="819"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="49"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="137"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="148"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="353"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="369"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="400"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="446"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="487"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="569"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="769"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="819"/>
            <end position="834"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1890825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="854" mass="90311" checksum="F55F0597F1DE112A" modified="2025-10-08" version="1">MASAVVPKPSFAKVAATSISITNQRRALGNADATVTKETAMASSTPTTKASGGKASAKVAKPPKFTSQSPSPETAQQGDIIEGVSKLVVSTTPNPAVNVNGSSLSINAKSATADSDDSHRTDSSDLGTKPPSLDGKSITSGTTTTFALDEKDSLRPDDSASVQAAADDDDSSVRGSLVAASHPPPFESCISIDAGLSGDISARVSPASDSSPDPVVAPVSAPANALDNIYQQAPDDKLLEAIESIKDRQFLLRLEIDVINFVQESKEPYMDLPPSNSFFRMLTHKLADYYHMTHSYEKDNGPGFVRIFRTPFCRVPPSLASIAASTKSPTPPPPILPMKIMRRGEDSKSTDPASSSAVQSKAASEVEGPDQKEKSDPKERKTREEREEAYNEARKRIFGTSATPVATNTTDNTSENDGENEMSRASSVSTKDKSTTNSRRGKNVKQRRDSGTFESRHNYVQQWSHPQPWGGSQPQPHYVPVGTLYQAQQGPPQHQNQHLAQTHPPYTGHVPPAFANGSGQVAGSIPTAHSYPSHGYVPNGQYPSHTPVGRFPQQGHSTAPYSHGASIPQWRSSPNVKSSQYGRGSMPSNPAMGPNSVHYPFGQLPISMNPYDAKTQHPIPGSYNRPGYNMSNQPFIPDSRAPAPGQPLPPTQAQPPMQPIYPAPPPQHMSPRMDTYGPMHYGPSPQMAYAQPCMAPPYSMAPHMPSHAPPPPPMGTYAHQPAPLPHHVYAPSYPHHVPAQSRPPVHQTGTGGKAQRTGTKKRNKPNAGAGAGAGTGGKTTGETSIALASTPCTISATNNFSNSSLPAIVDSGAAIAAAAATASKSSTTTSATGGQPFGNLPHYGNPATLPQKPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS91</accession>
    <name>A0ABR3YS91_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005066</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000160">
        <property type="protein sequence ID" value="KAL1891220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="195"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="268"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="162"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="195"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="316"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="393" mass="43887" checksum="FE35DD82990415DE" modified="2025-10-08" version="1">MSVSYQQPPSLGQDDLVALFSRTLTLTPNMAAQLAASMENPAMPLAAPTTFASQHYIHSTTSAATGAATAARPPRHHMSNDARLRAYGIDPNSLSPSQMQLFRIAESAQQSRLLDLWKIFPPSLPGEDPSHAWTPTNLETEEHRAIARFAKLVGQEQEKGQKPQTETGETSTHMDEDMAVEIESSPIDCDYAAQQQADQLRQQQQAAQAAQMSAGYPVQSPSGAWLRPTDTSASNDPFADDGCGGFCAPEPYMASGYEELMRRDAEREEHLRRMAQEEEMQIEMLRQQEQEKEMERILAEQFEMEQLQELERQSQERQLQQNRSSTGSLDGSMYVTFGSSSTQPAITYRPAAYDRVYDNSLVGTPRDLQCMDMMQHSQQHQLCHSMGDAMDTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSR6</accession>
    <name>A0ABR3YSR6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000169">
        <property type="protein sequence ID" value="KAL1890895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="415" mass="45201" checksum="4915789FD3B19E7C" modified="2025-10-08" version="1">MAFVASSESMADRRPRRPTDLQISSASHQHPFAHNSKPARYAEVRKDRGSMNSEASAPGLMDDQASDVSADDDYQYQASGDELWDSWQNDHTTFNGAYAMPATSTRSPELFFATNYAGSPLLSPSAAISSVRKDQPRPVGHEAFISHKASDSFSRSEHLVPPSTADPVSLLTPKFFDASSISYLPPQLPPPTSPLPQLPLRGPRSPRALRTAKSHGVLNRSDASVPPRSTSLARPMTPTARPGTTSSHHHSSSFAMRQGQGQGPRRPPRPDEKVLYSPFPTGTHSRNHSRSHSNANSITASGHASSNSTGTISPRAMQTVDSDDMQLLHQLCMERSRPMAAGARPATSGLSGLGQNKSAFDDDDSDDEVDSADSRPQTGLQRLMKGLQKRSSQEKWREPAAKEKNMFSRMFTRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT38</accession>
    <name>A0ABR3YT38_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF7137 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_004943</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000153">
        <property type="protein sequence ID" value="KAL1891466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055561">
        <property type="entry name" value="DUF7137"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42028">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42028:SF1">
        <property type="entry name" value="YALI0E30657P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23585">
        <property type="entry name" value="DUF7137"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047011805" description="DUF7137 domain-containing protein" evidence="3">
        <location>
            <begin position="24"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7137" evidence="4">
        <location>
            <begin position="124"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1891466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="294" mass="31460" checksum="3078AE52986D3FF2" modified="2025-10-08" version="1">MKISVTLTRVAVGLASAASVAQAWPSWMPPMDSLYVRQNNVGVNTAVASSSEDNNNNDASSTIDAFTVTNQDSTATTDNADSTATRTSDSEDATITSKGSSRSTSSRASSNRNSTRTVYTDALAQAGGMSMISPQTAAFKPLYKAGDFFTWEWNYTNIRATPTAIDLILSCSSITQSWTLTSNMTFATPATFVWDSSEQANDAQQPLVPNNYTLIIKDSEDSVTAAAEAGYLAVQSTFTFGVYTPAPYTPLADWECTTCIVGAASRPSNMVLPMVISSLMTTFGFMWFLNGLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUH6</accession>
    <name>A0ABR3YUH6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004958</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000154">
        <property type="protein sequence ID" value="KAL1891448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="318" mass="34984" checksum="AA5B674EADEF1F82" modified="2025-10-08" version="1">MVLDGAIQKTLAGSELPKAFQASAWEQESEGRTADRQKSTKAPKAPAATTGTATPGKSATEKVSRSWAQKTAQAGKEGETIDVRPKQAPKAKPTRKAPQENRLLARLFPGSKWKEVNPAIVKSKVNKYLFEGKEVVTQAKTTQTGFAITLSGEQCLRKEGTLELIRNYLDALALEKETVWEKYILKNVPRNVHDVTEKGSEIRRTSLEDVGAEIQKAFGGQLKILEFREYKDEPQVQGLRVAILNPERVPRTIELLGSERMVKKMEYKPPPGAGGSTGQNPAASPLGARYVEKQSTRPNPTKRRQSALNIRTRSASAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUQ8</accession>
    <name>A0ABR3YUQ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SIS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004911</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000151">
        <property type="protein sequence ID" value="KAL1891570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38418">
        <property type="entry name" value="SUGAR ISOMERASE, KPSF/GUTQ (AFU_ORTHOLOGUE AFUA_6G08860)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38418:SF2">
        <property type="entry name" value="SUGAR ISOMERASE, KPSF_GUTQ (AFU_ORTHOLOGUE AFUA_6G08860)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SIS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SIS" evidence="2">
        <location>
            <begin position="168"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="499" mass="51066" checksum="8BC6F07F46878EE2" modified="2025-10-08" version="1">MPSPPPPPPGPTLPLQTSAVVVPRKTTPDQCTYPAPPSPAASSHDDSVSTLDECSISDMDLSLKAGHSSTSNLTRTTSIASASAASRRRGTDAPPAVEPATTAAHFSSMSPSSPPSSTSPLSPTSSLQFADRLASANHVLSTEAAALAAVTHLYATHSVARAGFNAAVSAIVRNCGEKGKLVIIGVGKSGIIARKLVATFSSLGLCAIFLHPTDALHGDLGYIQPRDTLLVITYSGKTPELLLLQDHLPSDLPTILLTAHTRPSDCAFIRARPATILLPTPIPTPEKKSFGVSAPTTSTTTALAVGDALAVTAAHELHSAPGSLGLATVFARNHPGGAIGAALQNSAPPDPILRDLLALSFAELPLLEPCAGSRGALTGADALRAGFDAANTADAASAGSGWLRLCDGSVLPPSRIRALRNDQLLVPIGQVPGLVVARDEMLGIAADTQVRVAKDLVRSAHAHVPEGAAYLQVGDAIIALLDEMGQIVGALEANQVLSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUU7</accession>
    <name>A0ABR3YUU7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Gamma-glutamyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_004925</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000152">
        <property type="protein sequence ID" value="KAL1891553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052896">
        <property type="entry name" value="GGT-like_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043138">
        <property type="entry name" value="GGT_lsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043137">
        <property type="entry name" value="GGT_ssub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43881">
        <property type="entry name" value="GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43881:SF1">
        <property type="entry name" value="GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01019">
        <property type="entry name" value="G_glu_transpept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01210">
        <property type="entry name" value="GGTRANSPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1891553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="604" mass="63805" checksum="D407EFFB88246EEA" modified="2025-10-08" version="1">MTLDSSQTSTQYSGKTLHFNSRRSVVYSAKGIIACTQPLAAQCGLKVLQAGGNAADAAVAVAAGLNMTEPASTGIGGDVFMLYYDASTGKVSALNGSGRAGEKYTLERTRKDLGLAEDTNGLERIPMASVHAVTVPGAAAGWVDAVEQFGSGKISLEDILMPAIELGESGFPWVRSEELLRRASPNFAEILKNDPKSPGGVRAPLPGDLMRNPKLAQTFRTLGTHGKRGFYTGRIAEAIIAAVAARGGHLTLADLEHHMATAAAAETAPLSLRFSGQGLGAKNETIDLWEHPPNGQGIVALMALGIIQELEKQGKIPKWTASNHNTAPYLHVIIESLRLAFSDGTWFVSDPATTRVPATELLSSEYLSLRAKLFKAERALSAEEVIHGLSGTSTGDSPALNSCDTVYFCVTDSAGNAASFINSNYGNFGTGIVPAGCGFALQNRAANFSLNQKHPNVLAPRKRPYHTIIPGLVTHAHDGTLHSAFGVMGGFMQPQGQLQVLLGQIVGGLDPQAALDAPRVCIDSGTQRADGTVNWRVSVEDGMPQETIEGLKRLGHEVSVLKGFQRELFGRGQIIKRTVDAVEGTCIWSAGSDARGDGAAYPIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUX2</accession>
    <name>A0ABR3YUX2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">tRNA A64-2'-O-ribosylphosphate transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RIT1</name>
        <name evidence="4" type="ORF">Cpir12675_004676</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000138">
        <property type="protein sequence ID" value="KAL1892126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007306">
        <property type="entry name" value="Rit1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033421">
        <property type="entry name" value="Rit1_DUSP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033449">
        <property type="entry name" value="Rit1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31811">
        <property type="entry name" value="TRNA A64-2'-O-RIBOSYLPHOSPHATE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31811:SF0">
        <property type="entry name" value="TRNA A64-2'-O-RIBOSYLPHOSPHATE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04179">
        <property type="entry name" value="Init_tRNA_PT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17184">
        <property type="entry name" value="Rit1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007747">
        <property type="entry name" value="Ribosyl_Ptfrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rit1 N-terminal" evidence="3">
        <location>
            <begin position="47"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="Rit1 DUSP-like" evidence="2">
        <location>
            <begin position="367"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="486" mass="52762" checksum="ABD6981CC7F0974B" modified="2025-10-08" version="1">MSLADNTQLTPEDTPGHGAPVSATANIRFSDIILPQKESLSHLFSGLKRTSTSISNRLRSIAQDSCFVNRVATSYAPRKLVANERCGSWYVDIERKGGSAYFKSTDGHTDAWKISTRRLNVHLLRLIEEDDGCIIVDSTRRGKRMPDALSKTIPIWCAVLNTLLFPSLTSSHSLHTPPLVVSASEHAQISALIPSFAQTLSSISLDLPALRRTLTKPLRPLWITPDTPLPTSPPESIFADFRPVICCTASARSADGGGEISSGAGYVQGAADDTEMWAHGLTAPLFWAHRAELLETPETELPALMTQLAAKGGPGEENGLLEIIHGIYVASLPVDSEALVSESQQTCVIRLTSDTAPVTTTGSRVYSRGIGRHKAASRNLRIELAGICEFARKFIQKQKGSSENRQPVRIVIACETARDISVGTALALSCILYNDDGSYRSIIGTRANDFSKTTIRVRLGKIMVHCPEVNPSRNTLQSVNSYLMGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV55</accession>
    <name>A0ABR3YV55_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_004667</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000137">
        <property type="protein sequence ID" value="KAL1892158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007300">
        <property type="entry name" value="CidB/LrgB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30249:SF0">
        <property type="entry name" value="PLASTIDAL GLYCOLATE_GLYCERATE TRANSLOCATOR 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30249">
        <property type="entry name" value="PUTATIVE SEROTONIN TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04172">
        <property type="entry name" value="LrgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045163223" evidence="6">
        <location>
            <begin position="26"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1892158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="255" mass="26600" checksum="61A313EB7F03F12C" modified="2025-10-08" version="1">MLRALANPVLGTSLGLMLYTHLVATATHVQINTAVSAFNSGVTPADFLSRLLGISTAKSPTTPGAGDLAKSILDVGIVIWGFKLYECRTALFSLRGFLTLVVAAVAAVVNMVLAPVLARATRLSTAKSLAFAARCVTLALAQPATELVRGDLTANAVVVVANGILGQVMYPLVWRYCAWLSHGIYGGDRPVKTAAIGAVVGINGLALGVSHLYRENSPAAPYSVLSMAGFGVVTVVLLYSEGMRKTVREAGEGSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWF1</accession>
    <name>A0ABR3YWF1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Vacuolar protein sorting-associated protein 20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">VPS20</name>
        <name evidence="8" type="ORF">Cpir12675_004419</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000124">
        <property type="protein sequence ID" value="KAL1892720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1060">
        <property type="entry name" value="ESAT-6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761:SF5">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="171"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1892720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="229" mass="25296" checksum="569333BDAB305AD0" modified="2025-10-08" version="1">MGANGSKVTAQDKAILDMKIQRDKLHQYQKRITVLTAKETEIAKHMLAKGDKVRALLALRRKKYQETLLSKTDAQLEQLEHLVSSVEFAQIQKDVVFGLQQGTRVLQEIHKEMGGLEHVEKLMGDTADAIAYQKEVSDMLGGQISNSDEDEVEDELAALEAEVLGDSETVTAPPAHNVAHGEAPVTFPNVPTGDRVSHPLPNVPAQNPKYAVEKQPRPTSERQKVAQYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWT4</accession>
    <name>A0ABR3YWT4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Vesicular-fusion protein SEC18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SEC18</name>
        <name evidence="9" type="ORF">Cpir12675_004411</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000124">
        <property type="protein sequence ID" value="KAL1892713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004201">
        <property type="entry name" value="Cdc48_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029067">
        <property type="entry name" value="CDC48_domain_2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039812">
        <property type="entry name" value="Vesicle-fus_ATPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23078:SF3">
        <property type="entry name" value="VESICLE-FUSING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23078">
        <property type="entry name" value="VESICULAR-FUSION PROTEIN NSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02933">
        <property type="entry name" value="CDC48_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="ADC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54585">
        <property type="entry name" value="Cdc48 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="8">
        <location>
            <begin position="344"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="8">
        <location>
            <begin position="627"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1892713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="857" mass="94346" checksum="AC48F206AA7ABF1C" modified="2025-10-08" version="1">MSRNGPPYAQPPHGPDSGNLPPRRPAPNDSNALFGNRGAAAPPTVPGGYAGGSGYGQAPSAPRQHPMASRGPPSEKPRGGSNGPAINLQVAKVEDKTVQTRLIYENVCAVSSADFSPNPDGSDIYVLITNTDGQEFVMTARPIQHFPRGCISLSEPQRNWARISVRDTFTGYQWTPFQGNNKQVYIGTMDVEIGFASPNKKTAQKYKEDDLQKLFTRSFENHIIQPGQRILMDVSSIPLLVVVKTVTLIDLGMPVEGQASSRNHTTRGIITSESQIVFHRDAASDLQMEASMKRANTNAIIAPDFKFEDMGIGGLAGEFATIFRRAFASRIFPPAMVQKLGIQHVKGILMYGPPGTGKTLMARQIGKMLNSREPKIINGPEILNKFVGQSEENVRKMFADAEKEYKEKGDESGLHVIIFDELDAVCKQRGSGAGGGTGVGDSVVNQLLTKLDGVDQLNNILLIGMTNRKDMIDEALLRPGRLEVQLEISLPNEEGRLQILKIHTSKMRDNDVLGNDVDLISLAAEAKNYSGAELSGLVKAATSFAFSRHTKIDQLAGIKDDVANMKVTMADFEQALREVRPAYGVDEQDLDMLLPNGIIKFNPEHIQDILNQGERSFNTIREAEGKRHQAILFHGVRGAGKTALAAEIARMSQYPFVKVLSPKDLLPYRDEISKIDYINRVFANAYRSPLSLVLIDNFDRLIDWSPIGPRFSNNILATLQTLISTPPPKDHRLLVFCTTSKLRVLKLLEVDDVFDKKIDVRPLRSLNELATVMDHSRMFDRNQIQNICGQIQDTAVMTEAERRKGQFSVELGIKTVLDFLFEAKAASKPREDGSALDPGPIFLNLMVDAINAVKVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWV1</accession>
    <name>A0ABR3YWV1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNase III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004804</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000145">
        <property type="protein sequence ID" value="KAL1891799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040030">
        <property type="entry name" value="Ribosomal_mL57"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28160">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L15, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28160:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14622">
        <property type="entry name" value="Ribonucleas_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase III" evidence="1">
        <location>
            <begin position="104"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="258" mass="28521" checksum="B5CF5F1B1B76E370" modified="2025-10-08" version="1">MASRTVVGCFTRRTACTGLQRTAIGVSAHRSLSTTAVCHDEASSDNLNYRPRWSYTPEGMKAPFSPHITKVPSRSQWVVNNDPEILDIMYNRLLGRDGSQLLPDEIKWLAVTHKSFDQGRRGMNDRLAYVGRMAIIHECAKTIATSAPKVSETGPDEYGREPFNNTLVASLDNLTFEHPKDIASIENMERIGIEVGLLKVLRWKPRMPENLAASGQHVVLNSALQAIFGALLLQHGSEVAGTLIRERLIARLKASSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX35</accession>
    <name>A0ABR3YX35_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004778</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000144">
        <property type="protein sequence ID" value="KAL1891889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="362" mass="41503" checksum="F52B1F217B7E0854" modified="2025-10-08" version="1">MNVSRVGRYEHNVRSERRAQDAPRIRQLFKCSSRDPMYHMLEQLSPKYKMPPMDREPRAFLILNRFTCTSAIMFATDSVFDILGISSSEISNKSFYDLVHRSCRPESITCLENAKANDSLAYLRFWYQDPRVADDESDYGDGYGHYNNYDDNDYHDYEYDDYRYDGYSHERQAIRRSIEDNMPLHNRCGSSSNSAPIKHESSPSPKRRCVQRGSRRPATSYPPPTSINPSSTIPQVLDAIEAEGEPPWISRAGRHQRSSPRQSQPMEIEAVISCTSDGVGVVIRRARPPIPTAQPPRPPSDLSHALPASPYSSDHRISPSYDSYDAPEEMYTFRPLQSQHIGREGDDFDPGVEQHYGRRITR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXF6</accession>
    <name>A0ABR3YXF6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Vint domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004552</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000131">
        <property type="protein sequence ID" value="KAL1892438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039510">
        <property type="entry name" value="Vint_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14623">
        <property type="entry name" value="Vint"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="Hedgehog/intein (Hint) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vint" evidence="1">
        <location>
            <begin position="20"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Vint" evidence="1">
        <location>
            <begin position="164"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="273" mass="29713" checksum="FD426480AF5D7DCE" modified="2025-10-08" version="1">MRPSRRPHNGPTTITTPGAACFASSSLVTLASGNKLPLRHLRRGMWVQTPRGPRRVAALVMTTVHDHPVCDLHSVLVTAWHPVSREAQSWHFPRMVARGHGRYTGRMCSVLLEKDADPRAHAIWVSPAAHGSVRPANSVPQAPHSARMPGEVAPGVDAQQAEAGFWGVTLGHGVRKPSRYDVRAHPFFGNHTAVVCNLVSLGVGDGGVVLSGGLVKDRMTGLVTAFAPVTRRNDSTSTHRPDNRTVTMYVKTPNLRARYIRLVKRAAQRALRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXJ4</accession>
    <name>A0ABR3YXJ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Radiation sensitive protein rad9</fullName>
            <ecNumber evidence="6">4.6.1.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RAD9</name>
        <name evidence="6" type="ORF">Cpir12675_004297</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.16" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000118">
        <property type="protein sequence ID" value="KAL1893063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000213">
        <property type="term" value="F:tRNA-intron lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17745">
        <property type="entry name" value="BRCT_p53bp1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047249">
        <property type="entry name" value="BRCT_p53bp1-like_rpt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047252">
        <property type="entry name" value="TP53BP1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15321:SF3">
        <property type="entry name" value="TP53-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15321">
        <property type="entry name" value="TUMOR SUPPRESSOR P53-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="5">
        <location>
            <begin position="955"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="297"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="377"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="443"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="513"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="675"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="148"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="301"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="447"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="523"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="538"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="559"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="690"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="711"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="726"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="830"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="880"/>
            <end position="891"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1893063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1279" mass="137843" checksum="2318DDE09548DDA0" modified="2025-10-08" version="1">MGASRRPPPFYLSHLASSSTRASKAIVSAAINRTSALSATKKPVSSVADTFSHYNSYREAHSQAFANKENISHNIDITTITSLGVKHTATILSVPPGKLENDCKSTASSITPHANDSYQPYLPRPLASALAPASTYPDLDARPPQTTITAEMDVSQESTQTNDGRDYERAVEGDSLGDFHNDSLEKGDSGAVDFGLDTTANDNNTDGHGPEEAMSDPLSPIADLGLPLTRGNWRSVETPSQINSLGLRTTPFRRRPFGDPVTPKGNNNPFAHMNLQQSEMRPSQLFLASDSQLPSAIKMHSPTSSRPSPGDFNNSPIPMCQSSPTQLRKRASLSQPLDGFQSPLGVANGDYVVPGSPVETHRVLAPMRKHHSFLGARQTPQPQSLKRKAANMAAVSDNSDSESERLAARRNLAAQKRRKADRELDCISASNSVAAVAVAATDAGPESNVSSENTSDKPSSFPPTLLSAHTHVLAATEASIIPDSDEANTVIANSQLSAASGAVIKASVDVASRSASVPLASQRQKDLLHKEAVPETSPAPTRQSTNNAAPPSVSSLAENDTETADEGDNKEDTIVAPPSDPLKSKSPQRTLDSDDELLFSRLKLPLINPNMSTATRSLKSPTVSPLTSIGGHIPDTQIPPSSPSQRPTIIPREITESVPIGQDICLNIKDGMAPKASLESRNSGDENTDALVTTKPSKKTQATYSRRSLKPYPPRKTTPVPLPALSGQSVATDKAALTTSKPTRKRQKSLKQLDAEGVKSGNIAFHSETPEPAPTVTEDTPPRLPLKRPRGKANRIIETSEPPEDVKPSSSAASRLKRGSSAPRMRTISPAPSNRRLSTPLSDATEITSMPSSPIGRKKRSSVRSRTSLQQKCETLAKAQPKHKQKRKGSIRKNTVSRAVAPYSSEDELVQTPPAIKESEAGVPTPVTESHVARTIDMGSKKSSKGWVYVPIEQDRSSLFSNMVFALTFQSRELVSPAYEYERRVRINKDIEKKLVASGGRILEAGFEEMFQKSSAGSDIGGTGGLQIPLVLTAAAKNYGFTAVIADGYSRKVKYMQALALGIPCITYHWVEECIRKGAVVAWQPFLLTPGASICFDNAMMSRTLHPFPPTNTTLSTMIEHRLNFLSSHRILFVMKRSREEEKKRFYLFLMHVLGATVSRALSVTDARASLAEAEARNEAFDWVYIDEPTGSATELLDANGSARAGTKVKGGGARRKKRESTVDIESEAETALMAGLTKKLRLMSNELVVQSLIRGDLIDAETWESVKGNAGRGGGRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXX4</accession>
    <name>A0ABR3YXX4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">DNA polymerase</fullName>
            <ecNumber evidence="15">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="primary">REV3</name>
        <name evidence="22" type="ORF">Cpir12675_004225</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 15">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="15">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="15"/>
    <dbReference type="EMBL" id="JAWDJO010000115">
        <property type="protein sequence ID" value="KAL1893206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05778">
        <property type="entry name" value="DNA_polB_zeta_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05534">
        <property type="entry name" value="POLBc_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.342.10">
        <property type="entry name" value="DNA Polymerase, chain B, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.690">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056435">
        <property type="entry name" value="DPOD/Z_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030559">
        <property type="entry name" value="PolZ_Rev3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056447">
        <property type="entry name" value="REV3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025687">
        <property type="entry name" value="Znf-C4pol"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45812">
        <property type="entry name" value="DNA POLYMERASE ZETA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45812:SF1">
        <property type="entry name" value="DNA POLYMERASE ZETA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24055">
        <property type="entry name" value="POL3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24065">
        <property type="entry name" value="REV3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14260">
        <property type="entry name" value="zf-C4pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="15" id="KW-0235">DNA replication</keyword>
    <keyword evidence="15" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 15" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="10 15" id="KW-0408">Iron</keyword>
    <keyword evidence="11 15" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 15 22" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 15 22" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 15" id="KW-0862">Zinc</keyword>
    <keyword evidence="15" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNA polymerase zeta catalytic subunit N-terminal" evidence="21">
        <location>
            <begin position="4"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="DNA polymerase delta/zeta catalytic subunit N-terminal" evidence="20">
        <location>
            <begin position="61"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B exonuclease" evidence="18">
        <location>
            <begin position="931"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="17">
        <location>
            <begin position="1198"/>
            <end position="1660"/>
        </location>
    </feature>
    <feature type="domain" description="C4-type zinc-finger of DNA polymerase delta" evidence="19">
        <location>
            <begin position="1699"/>
            <end position="1788"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="814"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="901"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="915"/>
            <end position="924"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF14260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF24055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF24065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAL1893206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1812" mass="202370" checksum="55DCF210452E8115" modified="2025-10-08" version="1">MDGFRVQINAIDHYQTPPSPYTPVLRNDVSASQAYQLPHVPVIRIFGATTAGQKVCAHVHGFFPYVYVPYEGSLEPKKVGSYIYRLHVSIDHALSLIVRRPTSRLSRHPKFVARITLVKGVPFYGFHVGYSFFLKIYMFNPNIMNRLVDVLQNGAIMQTRFQPYEAHIQYLSQFMIDYNLFGCDWLDADKTHFRAPLPEAFEEDARQLQEDGNKNRLRGSQPSLSLLYNDSTVPACFVTDDSTLPRSSYCTLEVDISVCDITNRRSLTERCLHHDFIERLYPVPESVKLVPSMAGLWRSEEQRRRALGLSASNSSPFPPDVLVSMSPDKKGTIETGFMGEEEQRKQVAQLIEAEYDPNITPLFETFVKHHPRADSVRTVMESVEDLYPDNLQAVLGLAPQCVDDASVENPPLEDIEVDEVHISLSQDPINDDVANEIQDTEDIDHMDEQARRDFGAQSPEAAENEEANIEGLLTSFVGLSRSGLYSGTPPKISVDTSLIEAACSDRFSPGLRRVPGTTKARGKRFFTSSPDVRPGLNHKKMKIGPVSSYIPVVIEESGSLDVEETLAKGKANIDKKRVSFKPLVGANQALSVQRDSQPVMTEDGRNIEEWLQRNTDLISSSLEFPSTPATSRLNRASFMHHSPLPVRSSQDALSPAGSRLFIANSRAPPVSPFLLRTPRHAQRSLIFTTPFKTPHSKLSWPISSSPFSIRKAGCSSSPFPACKQTPDSNTRPLLSQRTARTHTFVFSTPPPEVAEVCSSFGQYDLPEVINEEVTYSVEADVPTRPHEYGGKTFRLRSNTLPFLPEFEIDAGHANNNSNLLDEPDSKANKNRAKASQSRSLPQDVRCQICSIKAWDFFPPPPSFQEVKAWDMARHAASMSSSRPNQRLSSQYMLRSQHFASQIDGPTPAKRGSAAITASQRQRSTGLKPETRSMSILAIEIHVNTRGKLMPNPEHDSVQFVFWSLQTDQSYADVVDLEDPTPDQAGIVSGVIVLSEESTELAQRIKRQTKWVVQAEDTELEVLTAVAAMVRRFDPDILTGFEVHSGSWGFLLERAAAKYEYDLGEDLSRMRSDPASRLHKDGNSARWAFTKTSTVKVTGRHTINIWRAMRGEMSLSQYTIENVAWHLLGRRIPHYSHAVLTAWHKASSSADACAGGGHRAMARLLRYYQLRTRLDLEILEANELVVRTRERARLLGVDFFSVISRGSQFKVESMMGRIAKPENYVFVSPSRKQVGGQNALECLPLVMEPQSALYNDPVVVLDFQSLYPSVMIAYNYCYSTFLGRIVGWGSGATNKMGFTQYTRAKHLLTLVQNSVTIAPNGMMYVTPAVRTSLLAKMLREILETRVMVKSGMKNAKKSVHQLLNNRQLALKLLANVTYGYTSASYSGRMPCAEIADSIVQTGRETLERAIAMIHTHPSWKAEVVYGDTDSLFIRLPGRTKASAFSIANEMAVAITAANPRPVKIKFEKVYQPCVLLAKKRYVGYKWEHPSQDTPVFEAKGIETVRRDGTPGEQKIQEKVLRTLFDTADLSRVKAYFQRQCDKILRGHVSLQDFCFAKEVKLGTYADSSGGVHNYRRPNQPQPPALPPGALLAARKILVDGRAEPQHGERVPYLVIAGVPGSRLSDRCVAPSEVLDSPDAELDADYYINKNIIPAIDRILQLVGASAKRWYDEMPKVKRVRRIDPKRRSAVIEAYLSVASCIACKSHLPPRTASTAITAKTTSGRGAGDTLICMRCLAQRPQTLTTIQQRMSALNTSLGNIRAVCRSCAATAFGDEIACDSLDCSVFWTRSKMEARTRSEGEMLREAERKLLEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYB6</accession>
    <name>A0ABR3YYB6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NAD(+) kinase</fullName>
            <ecNumber evidence="7">2.7.1.23</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">UTR1</name>
        <name evidence="7" type="ORF">Cpir12675_004216</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.23" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000114">
        <property type="protein sequence ID" value="KAL1893238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00361">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20275">
        <property type="entry name" value="NAD KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20275:SF0">
        <property type="entry name" value="NAD KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20143">
        <property type="entry name" value="NAD_kinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="490"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1893238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="541" mass="59285" checksum="23DE6CEA3D4E3ACD" modified="2025-10-08" version="1">MQAEKARKIPPPLRPTNLSFVARVHKPHALSLSEMLSSFNTSSFGAAAAGSGSGSGSGSGATAAISNGPISAPFSKDAPADPSSLADALNNLGMTSAGSTPSLSTAIPALRSPCFYHKRFDDAVDIDRVLEEIKGDESMSHSRLVQTATSVREISKQLQRRPIKRAVRNVMVVTKARDNQLVYLTRELAMWLMRTPRYGSDVGVNVYVDAKLRNSHRFDADGLRAMDPRFDSMLRFWSPDLCWTQPEKFDLVLTLGGDGTVLFTSWLFQRIVPPTLSFSLGSLGFLTSFEYERYAAHLNRVMGDAGMKVNLRMRFTCTVFRNAGLNKPPVSEGEQFEVLNELVIDRGPSPYVSNLELYGDDELLTVVQADGCIFSTPTGSTAYSLSAGGSLVHPDIPAILLTPICPHTLSFRPMVLSDTMALRVCIPHNSRATAYCAFDGKGRVELRQGDCVTITASQYPFPTVTRTDTEWFNSVSRTLRWNTRAAAQKPFNASPISGDDEGQRKDEDPEWDIDTDSAYYASEDCSQAASPLQRQMSMLGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYI8</accession>
    <name>A0ABR3YYI8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pre-rRNA processing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RRP9</name>
        <name evidence="7" type="ORF">Cpir12675_004104</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000109">
        <property type="protein sequence ID" value="KAL1893451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039241">
        <property type="entry name" value="Rrp9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19865">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19865:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="229"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="271"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="313"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="448"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="32"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="196"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1893451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="575" mass="63722" checksum="D4F33EA7F46004E7" modified="2025-10-08" version="1">MSSFFTVPGQKKRKRAAGADSAQKRTIPTRFKPTASTKNKSSSAKQNVSDDDESISGSDSEMADSAPEDAEDSSAELSSEEEGETGAERRLRLAERYLENIKEQVDTIGFDAAEIDRDMIAERLQEDVAESKGKVYRNLVEDLAFDQASHTLWKANTLTFTSIAVHEPFAYTVTKDMYLQKWRVQDLPQNQFPQTTRRKPRKPPAPPRKKPTLVSWIRGDRKKAKDKEYKRHVGEILCVAVSPDGQFVATGGADRRLIIYNAETLTPLRVFTHHRDSVTGLAFRRGTNQLFSSSKDRTVKVWSLNELAYVETLFGHQDDVVDVAALAQERCVSVGSRDRTARLWKVAEESQLVFRGGSSDKKKHHQSDPAAARIPHEGTMDRVAMIDDELFVTGSDNGSLSLWSVAKKKPLSIVPVAHGFEPRLLPTEASAEIDASSSVVPDPCPRYITALCTVPYSDLVLSGSWDGYIRVWQLSDDKRTLEPVGVLGDSEPVVDDQDTEKPFLVKGVINDIDLFERGDRGKDGLCVVAAVGKEHRFGRWKVITGGRNGGVIFEIPRGALKSASTDSIIESSVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYK5</accession>
    <name>A0ABR3YYK5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ATP-dependent RNA helicase DED1</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP-dependent RNA helicase ded1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="primary">DED1</name>
        <name evidence="20" type="ORF">Cpir12675_004106</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">ATP-binding RNA helicase involved in translation initiation. Remodels RNA in response to ADP and ATP concentrations by facilitating disruption, but also formation of RNA duplexes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 22">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000109">
        <property type="protein sequence ID" value="KAL1893453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17967">
        <property type="entry name" value="DEADc_DDX3_DDX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044763">
        <property type="entry name" value="Ded1/Dbp1_DEADc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 15 20" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 15 20" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="19">
        <location>
            <begin position="180"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="17">
        <location>
            <begin position="211"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="18">
        <location>
            <begin position="413"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="575"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="629"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="14">
        <location>
            <begin position="180"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="57"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="98"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="122"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="578"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAL1893453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="670" mass="71800" checksum="02ABB76EB0B5B65D" modified="2025-10-08" version="1">MADQLNMGGLSINPEGQQSQQAPPQQQHQHQHPGGRSYVPPHMRQQGQPSGQNSDESGMNNNRSNSGRNYEGGGGRNWTNHSGEGGGGRGGRWNNRGGYSGGHGRGGNNEGGGNNSNPRGSGDGEWRDGKHISGPANPRVERELFGTADDPSKQHTGINFEKYDEIPVEASGRDVPDPVITFSIPPLEEHLVRNIELSRYKVPTPVQKYSIPIVMGGRDLMACAQTGSGKTGGFLFPILSQAFIHGPSAVPATQGGNFGRQRKAYPTSLILAPTRELVSQIYEESRKFAYRSWVRPCVVYGGADIGSQLRQIERGCDLLVATPGRLVDLIERGRISFQNIKYLVLDEADRMLDMGFEPQIRRLVEGEDMPDVQNRQTLMFSATFPRDIQMLARDFLKDYIFLSVGRVGSTSENITQKIEYVEDVDKRSVLLDILHTHGTGLTLIFVETKRMADSLSDFLINQNFPATSIHGDRTQRERERALEFFRNGRCPILVATAVAARGLDIPNVTHVVNYDLPTDVDDYVHRIGRTGRAGNTGVATAFFNRGNRGIVRELIDLLKEANQEVPSFLENVARESSFGGGRGGRGRGGSSRASGSNRDFRKVGGGGGGNSGGYNGGNSGGYNQGGGGGGGSGSGYSGGAGGYSGGGGYGGGGGGYGNPAGQGQGPGGWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYL1</accession>
    <name>A0ABR3YYL1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RAD50-interacting protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000120">
        <property type="protein sequence ID" value="KAL1892935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.670">
        <property type="entry name" value="Dsl1p vesicle tethering complex, Tip20p subunit, domain D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042044">
        <property type="entry name" value="EXOC6PINT-1/Sec15/Tip20_C_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007528">
        <property type="entry name" value="RINT1_Tip20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13520:SF0">
        <property type="entry name" value="RAD50-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13520">
        <property type="entry name" value="RAD50-INTERACTING PROTEIN 1 RINT-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04437">
        <property type="entry name" value="RINT1_TIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51386">
        <property type="entry name" value="RINT1_TIP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="25"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="779" mass="87720" checksum="698D156F298D2B90" modified="2025-10-08" version="1">MAEMTPIDMRIADYLDDRLQTLDDFSSLDELLASVEDQRDQLQRQLDSTINDLEHARSAQDVEEASLNERIAEFQQLQKKIDESVATASTAAAPTEAIQRLQEPLRKIQTVELAQSYLELLQDAHDLKTQALKKVVDSPKAAIVPYGQLKGLADNMRNLHSAADEAAVHLVGYIETLATDLWAELKTATATQLETILAARQWPMVDPESEMDDEWILCVDKVLELQSSEILSVKHAVSLLPFDVMCKVFISEFEYHFMSDKPTSAAQSATTHCFPWFLATIEKWDDFFRDNLGYLMALKVKNTPVSNNLVYVDPVCAFLTTMLPAMQRKAELVLKEISGHGALLSQFIIALMDFDDSIRAKFNYDDGSRDGWAGLTTTILDKWFDPWFMAERKFAMERLQSIMEAPDSKTIDYDYGGVGKTKPTKGAVKVTDLLKSVTMQYQRVRKFKHRLKFLINIQLDIMDEYHDYLSNSLQAYQAMTSTVGRTLHGLTKEQAAALEGTGGMESLCKVYGSSDHIITTLKDWSNEEFFVALWYELHGRTKKNDHRRVTSGVSVEQVKDRISTAVDSETREGVLFDETIMAYTHRKKLAHELLVGAIVGSHNKALRLYTGHLQWTTLLEDAADISSLSITPELETTLSTIARNLEFLSKILGSAPLRRTWRAALDKLQFSLWSDVLTRQNFTAYGAAQFARDVEAVCSVIERYIPGASSSINSLAEGSKLLNLPIESSEKNSLTLKKVTDMVFTDNTEAKKVLSELGMENLSPVNARNILERRVETQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYZ1</accession>
    <name>A0ABR3YYZ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Proteasome regulatory particle base subunit rpn10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPN10</name>
        <name evidence="5" type="ORF">Cpir12675_004046</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S5A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000107">
        <property type="protein sequence ID" value="KAL1893616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027040">
        <property type="entry name" value="PSMD4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10223">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10223:SF0">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="4">
        <location>
            <begin position="5"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="237"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="237"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="270"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="285" mass="31161" checksum="DBD1A15D4ACF6D2F" modified="2025-10-08" version="1">MGLEAVMIVVDNSESSRNGDFSPTRFDAQTDAVNQLFRNITSSNPESSVGLMSMGGNGPEVLSTLTTEPGRIYSGMHRIKKQIKGESHLATGIQIAGLALKYRQNKLQRQRIIVFLCSPLEEDDKKLQQLASRMKKNNVAIDIVMFGQPDEEAEARLRKFNEEVKGAEGSHLVVIRPSGKLLSDELLTTPIVLGDNATGDRARAAASEDYGEFTFDPNTDPELALALRMSMEEENARIARESAKEDNAAIKASLESVKEEGESAPLLGESSKKNDKDDGDKMDTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ13</accession>
    <name>A0ABR3YZ13_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SCP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004276</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000117">
        <property type="protein sequence ID" value="KAL1893085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05380">
        <property type="entry name" value="CAP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018244">
        <property type="entry name" value="Allrgn_V5/Tpx1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01009">
        <property type="entry name" value="CRISP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP" evidence="2">
        <location>
            <begin position="175"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="174"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="342" mass="36482" checksum="AE2ABDD5DA3057EC" modified="2025-10-08" version="1">MKTSIAMAVASAALGLAGPLQIRKLVTLYEVETVTAYIYPNGDPAPAPTSGGKVKAADYGDSYFMNRKKPKVDKVLTTTTTWTTAYPVVYETPAPAPVYEPAPSEAEPVYVPTQAPEPVNVPTQEPEPVYAPVKTPKPVYAPIEEPEPVYAPVKTPEAPVSSTPASTDNNYGGSSESQASLSSHNIHRQNHSASALAWDENLASYALTSAQKCVFEHDMAPGGGGYGQNIAMFGTTDDMPDSGTAIKQAVTNMWYNSELDLFPGYGSEPDMSNFKAWGHFSQIVWKGTQKVGCASFKCAAGTMAEMDSWYTVCNYSPSGNFGGKYAENVSPPAGMSKSEVVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0V3</accession>
    <name>A0ABR3Z0V3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PHO89</name>
        <name evidence="8" type="ORF">Cpir12675_003946</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Sodium-phosphate symporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000102">
        <property type="protein sequence ID" value="KAL1893827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101:SF80">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="426"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="451" mass="49371" checksum="29AACE2015AEB59A" modified="2025-10-08" version="1">MKQAMFIASICEFSGAVSVGSRVSDTIRTNVIQHDYFKDHPSVLLLAMMCTLIGSSTFLTIATRHGFPVSTTHSIMGGILGASTAAMGISDINWGIHGVSQVFVAWVAAPGIAGVLGSILFLLTKNIVLVKKNAAKMALYTVPFYTFITVAAVSMLIALHGIQFRKDLSKSEILGSVFGAASTATILCVVFVMPYMWRKILYEDWTLRWYDMWRGPFLLHLPPPPPMPIGYEKVHIKDYYRGYLTPEELASIRASQAMINSVRSGPNDAPDLECCDAFSMMPPTALSSTNLSTDSSTAAATSASLAATTSYCPESDIPPRPPGSWLRPAVLLWRTNRILLRGVEKDVVRLQKMNSVMNWDIADMHSRAPRFDNRAEHMYSYVQILTAAAASFTHGANDVSNSIAPLTTAYRVWQSGRVQPEVGVPLWILVLGGACIVLGLLTYGYHVIRNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0X5</accession>
    <name>A0ABR3Z0X5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003932</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000101">
        <property type="protein sequence ID" value="KAL1893864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051207">
        <property type="entry name" value="ComplexI_NDUFA9_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126:SF16">
        <property type="entry name" value="MIOREX COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="2">
        <location>
            <begin position="6"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="121"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="287" mass="30327" checksum="8DA836FEBC68A9D4" modified="2025-10-08" version="1">MATKRIVVCGGNGFVGSRICKFAVAQGWDVMSISRSGQPRWDAVSASSTAPSWARQVSWERANLLDATTYRALLINTDYVVHSMGILLETDYKGLVRGTGGVISGLRGLLGGGGTNPLERGGSSRSTSASSGVGSQPTYESMNRDSAITLAREAAAANAKAFAFISAATCPPGVPTRYLSTKLEAEQSISKEQLRSIFIRAPFMYDSSRKLTLGIAAAAGAAQFLDGASKGLLSGVLGDKNKLVKPLLVDKVAQATVQALEQEEVSGGVGVEEIERLGEKYWRQSML</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z196</accession>
    <name>A0ABR3Z196_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">UV-damage endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MUS18</name>
        <name evidence="4" type="ORF">Cpir12675_003849</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000098">
        <property type="protein sequence ID" value="KAL1894065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004601">
        <property type="entry name" value="UvdE"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00629">
        <property type="entry name" value="uvde"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31290">
        <property type="entry name" value="UV-DAMAGE ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31290:SF5">
        <property type="entry name" value="UV-DAMAGE ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03851">
        <property type="entry name" value="UvdE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="2" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="41"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="216"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="557"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="128"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="154"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="563"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="574"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="600" mass="68227" checksum="14ED155FB595C1EA" modified="2025-10-08" version="1">MVVTRKSRRLQELVIRPQSDKALAVLTTTTDSSSCISTVIATSRKRPRTSSSATTTKEVTRTFKREEGDSSDGAEEQLPETPKKPSRTAKRVKREPESDVEESDFGDDEILSGCCESDDDFGLDTPPKKPKPNSKQKRAPLKPAKTKKSKKVVVKAEDSTKEPPETMPRLLPLTGGSLPLPWKGRLGYACINTYLRTLNPPIFSGRTCRMSSIIEHRHPLQDPSRPEHPTKNRPDMKKPASIERGQRYVEAIGLANARDIIPILRWNDRFGIKFMRLSSDMFPFASHKEYGYPLTPFAAEVLGEVGRTVAELGHRVTTHPGQYTQLGSLRKEVVDSAIRDLNYHDEMLSLLKLPEQADRDAVMIIHLGGTFGDKAATLDRFRANYERLSVSVKRRLVLENDDVSWSVHDLLPICQELEIPLVLDFHHHSIIFDEEALKDEGTTDVTNLYDRIKETWDRKGIRQKMHYSESRPGAITSRDRRAHSARVKELPPCPPDMDLMIEAKDKEQSVFELMRTYKLDGWEKVKNVVPDDRSDEWAVYWPEGRDDLLKVRKVRKKKSDLDLGVEVDAETETEESKAIPEKKTRAKRVSTKKAQNEVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1M4</accession>
    <name>A0ABR3Z1M4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BAG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003629</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000089">
        <property type="protein sequence ID" value="KAL1894503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.120">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036533">
        <property type="entry name" value="BAG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003103">
        <property type="entry name" value="BAG_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02179">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63491">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51035">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAG" evidence="2">
        <location>
            <begin position="210"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="270" mass="30677" checksum="1687947A0FBB115F" modified="2025-10-08" version="1">MSRLRHSWNSDNAPTGSVNISTKDYSYITPEDIGKDNLFWQSSDSHNSSETADDVIYLVYGDEKLRTCFPPYSIADGKVCVRDLRTRAGLLFNITGKPLQAANLKYKGRPLGGEDDVVRQFNVKNKSEITICHIESGDDSRSSKKSKPKRRTRGLNDSESADQAGASSSSRPETKPASTKGLTPMEQINIIEKWFDTEMLDKCQVFMKTPPSDSKKREQEWRKLTELTMQNVMLKLDAIETNGDQDVRNRRKEVCKRIEDIMKMLDQAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z211</accession>
    <name>A0ABR3Z211_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal 40S subunit protein S13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS13</name>
        <name evidence="6" type="ORF">Cpir12675_003579</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000087">
        <property type="protein sequence ID" value="KAL1894640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_A">
        <property type="entry name" value="Ribosomal_uS15_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_uS15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023029">
        <property type="entry name" value="Ribosomal_uS15_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012606">
        <property type="entry name" value="Ribosomal_uS15_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="uS15_NS1_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006331">
        <property type="entry name" value="PRK08561.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11885">
        <property type="entry name" value="RIBOSOMAL PROTEIN S15P/S13E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11885:SF6">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08069">
        <property type="entry name" value="Ribosomal_S13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01386">
        <property type="entry name" value="Ribosomal_S13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="S15/NS1 RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00362">
        <property type="entry name" value="RIBOSOMAL_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS15 N-terminal" evidence="5">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1894640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="151" mass="16950" checksum="835F52E51DD771B6" modified="2025-10-08" version="1">MGRLHSNGKGISASTIPYSRTAPAWQKTTPDQVSDQICKLARKGASPSQIGVVLRDAHGIAQVKVITGNRIVRILKSHGLAPELPEDLFNLIKKAVTVRKHLERNRKDKDAKFHLILIESRIHRLARYYRRIAQLPPNWKYESANASTLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z271</accession>
    <name>A0ABR3Z271_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Nuclear mRNA export, poly(A)+RNA binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MEX67</name>
        <name evidence="11" type="ORF">Cpir12675_003775</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NXF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000095">
        <property type="protein sequence ID" value="KAL1894133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14342">
        <property type="entry name" value="UBA_TAP-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002075">
        <property type="entry name" value="NTF2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030217">
        <property type="entry name" value="NXF_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005637">
        <property type="entry name" value="TAP_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10662">
        <property type="entry name" value="NUCLEAR RNA EXPORT FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10662:SF22">
        <property type="entry name" value="NUCLEAR RNA EXPORT FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22602">
        <property type="entry name" value="NXF_NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03943">
        <property type="entry name" value="TAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00804">
        <property type="entry name" value="TAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51281">
        <property type="entry name" value="TAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NTF2" evidence="9">
        <location>
            <begin position="402"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="domain" description="TAP-C" evidence="10">
        <location>
            <begin position="622"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="53"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1894133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="676" mass="73149" checksum="2398612C88A913CF" modified="2025-10-08" version="1">MAPGGRNNRGSGSTRTNTNGNKSSQTVGNSGINKRRGTRTDLDGDLDMDSGSARRTATATKGRNANAGRNTRGYAPNRISSNNLDAISKHLTGDDARPSRRGNNHQNSKTPLVWLRVTGLKESKAITNSDGGIANLLQFMERKASSNAGRSASKPIAIRQHRHIDPHVLVAASADDVEALRSINNLVFAGAILTVEDCPPPDSANSQGKSAFTLELENTLKSILAERYVADGKLLKLDSLAENQFIKSSGLMANTERAGKLFQSLMKICNDLFKTRSAKQEAIESITIAGNGISNVSQVECLATTFPDLKNLDLSNNLIATMRGIDSWRSKFQKLETLFISGNPLESAASNHIKTLLTWFPKLQNINGNVVRTAEGIRLAEEAARPHPIPQAGTDFRDEHGVAQAFLLDYFALYDTDRDALASKYYDMASTFSLAVDIVGPRDKALPVLSWSPYLRSSRNLKKITTFSGRTQRLFTGSNIIRQLWKNLPRTSHPNITTDLNKFVVDCHPLPGLRDPTGASVVGVDGMIIILHGEFDEQEKDTNNIGKRSFSRTFVLGPGVPGANPIRVVSDMLSLRAYAAVPNVYSTPAAAAPAAAAPTTTATIPATVSPGVVVPGATVAAPDQKAILEELCKQTRMVPMYAEMCLSDPNVNWNFEKGLALFNERRGNLPPDAFMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2D2</accession>
    <name>A0ABR3Z2D2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Phosphoacetylglucosamine mutase</fullName>
            <shortName evidence="11">PAGM</shortName>
            <ecNumber evidence="4 11">5.4.2.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Acetylglucosamine phosphomutase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 11">N-acetylglucosamine-phosphate mutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">PCM1</name>
        <name evidence="16" type="ORF">Cpir12675_003530</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23804"/>
            <dbReference type="ChEBI" id="CHEBI:57513"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="EC" id="5.4.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route I): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.3" evidence="4 11"/>
    <dbReference type="EMBL" id="JAWDJO010000085">
        <property type="protein sequence ID" value="KAL1894789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004610">
        <property type="term" value="F:phosphoacetylglucosamine mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03086">
        <property type="entry name" value="PGM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.120.10">
        <property type="entry name" value="Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.50">
        <property type="entry name" value="Alpha-D-phosphohexomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049023">
        <property type="entry name" value="AMG1_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049022">
        <property type="entry name" value="AMG1_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016657">
        <property type="entry name" value="PAGM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45955">
        <property type="entry name" value="PHOSPHOACETYLGLUCOSAMINE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45955:SF1">
        <property type="entry name" value="PHOSPHOACETYLGLUCOSAMINE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21405">
        <property type="entry name" value="AMG1_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21404">
        <property type="entry name" value="AMG1_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016408">
        <property type="entry name" value="PAGM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="Phosphoglucomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="Phosphoglucomutase, first 3 domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11 16" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="13">
        <location>
            <begin position="64"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoacetylglucosamine mutase AMG1" evidence="15">
        <location>
            <begin position="213"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoacetylglucosamine mutase AMG1" evidence="14">
        <location>
            <begin position="309"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase C-terminal" evidence="12">
        <location>
            <begin position="466"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR016408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF21404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF21405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1894789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="546" mass="58977" checksum="A2F0957F46202667" modified="2025-10-08" version="1">MSLSDNDQKLLEASKKHPVISLGEGRLYKYGTAGFRMKADLLDGVCFRVGLLASLRSRKLGSQAIGVMVTASHNPPADNGVKIVDPLGDMLEQDWEVYATKLVNAPSDEALVVAYNSLAAQLKIDLDTSSRCIVGRDTRPSGFNLVVALKDAWDATNTHSADYKQLSTPQLHYLTRCINTEGSPRAYGETSEAGYYQKTADAFVKALHGKKVSGQVIVDCANGIGGPKLHEFLKYVPAETGLDVKVVNDDVLRPEVLNLDCGADFVKTRQRAPPSPRPVPGVRSCSLDGDADRLMYYYTSPTQGFMMLDGDRIATLAASFIGDLLRSAGLEGSLTIGVVQTAYANGASTQYITRNLSLPVLCTATGVKHLHHAAQKFDIGIYFEANGHGTVLFSNTAIAAFANTQPQSPAQKEALDILAACAEMINQTVGDALSDMLMVEVVLAHKNWSMEDWAVVYTDLPNRLQRVEVPDKDAFKTTDAERRLVSPQGAQAGIDEAVSKYTNARSFARASGTENACRVYAEAATNAEVDELIKRVVAHIVSVANQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2S0</accession>
    <name>A0ABR3Z2S0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">LON peptidase N-terminal domain and RING finger protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_003620</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000089">
        <property type="protein sequence ID" value="KAL1894494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16514">
        <property type="entry name" value="RING-HC_LONFs_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="entry name" value="LON domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327:SF42">
        <property type="entry name" value="LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN C14F5.10C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327">
        <property type="entry name" value="RING FINGER PROTEIN 127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="226"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Lon N-terminal" evidence="7">
        <location>
            <begin position="319"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="192"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1894494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="617" mass="67613" checksum="ECCB6D12236AD759" modified="2025-10-08" version="1">MSTVLPLSASAASLRDALEVLQCAQCAHILREPMTLPCGRSLCRRCLPQPHTRRLVSYPATAEREAGIACPFKTCHKEHAVFDCGLDYVLGNMVEIVREGLKGAEAVYDGAASEGSGHSAALPNSDHRQLTTIRVLAETEEKGETEIDIEDAPVKTRSLIFSVHGTLLQALFLLAEVHGLPRIAKLDISSSSPPPQSSPLLPQPEPPSDSSLLNAILSQIRLEADCQVCYAIFLDPVVTPCGHTFCTVCLHRVLDHTPHCPVCRRSVSIAPLLSSINKPINRCLAQMLETFWPECVASRRRAAIQEGWTLSAILDSDSASSLAAERVPIFPCSLAFPGIPFFLHIFEPRYRLMVRRCMEGSRIFGMVLPRWMAGDGVADGSESEEFAAYGTLLRISKVSYFPDGRSMIETVGQGRFKIRSYTWEYGIVMGAIERLHDMGIAEEEAHEAADLSAAYAQHYTVPRFAEYFPAAPDAWPPASSRRRSLSRAASALEAILSRNTSDSSLTLTDPFSDLPPPTGAQPRPNISAMSTAELLDFARACAAHLSGSSSRLEDTFGPAPADAALFAWWFAAAMPMSEDKKYALLKSTSVRDRLKMCCMWALEWEGARWSVPRCVIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z334</accession>
    <name>A0ABR3Z334_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ADP-ribose diphosphatase</fullName>
            <ecNumber evidence="4">3.6.1.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">YSA1</name>
        <name evidence="4" type="ORF">Cpir12675_003600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.13" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000088">
        <property type="protein sequence ID" value="KAL1894611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047631">
        <property type="term" value="F:ADP-ribose diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18888">
        <property type="entry name" value="NUDIX_ADPRase_Nudt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11839:SF1">
        <property type="entry name" value="ADP-SUGAR PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11839">
        <property type="entry name" value="UDP/ADP-SUGAR PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="51"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="205" mass="22811" checksum="5F39EF97D759CA2E" modified="2025-10-08" version="1">MSASDSKHISFTKLPESEAVWTKLVKCTYLDPAGTQRTWESAERTTRPKDCDIDGVGIVAILERESGPEIMLQKQYRPPVERVCIEIPAGLIDAGETAEQAAVRELREETGYVGTVKDVSPIMFNDPGFCNTNLRTVHMTVDMSLPENQNPKPQLEEEEFIEVFFVPLNSLFAECKRLEAEGYAIDARIGTLAEGIEVAKAFKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z370</accession>
    <name>A0ABR3Z370_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C2H2 type master regulator of conidiophore development brlA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_003583</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000087">
        <property type="protein sequence ID" value="KAL1894644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF19">
        <property type="entry name" value="YY2 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="390"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="357"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="408"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="83"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="239"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="83"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="149"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="186"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="283"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="314"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1894644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="448" mass="48224" checksum="AB25DFCCD3C6B4FC" modified="2025-10-08" version="1">MDFHAQPTFDSVQMRSASGVGPSMSTSHSLNQLTHINPINHQQYSSQTQWTNNATPTSTSAHHYPASMYQAPASASSNSTATINNLLNDTTSNTTHSTHSTHSQHSLPHPHSHQLPQIQAHAQAAHAQAYEMMGFGRPPSMSPTTFTDSAYSSSASPSSPTYTLASPASPLGLPHHFGLGGSSGPNSARGSMSAPRQTPGGRSFSHDSTNMMHPSALAAAAQQHQQQHQTASNVHSSGLYQFDHGASNAFTPRTQTSYNSAHTGSHSTHGPPDYGLLDPNAGAPSNNLSTVTSANMQHASAAASTAGMIQPLRQQPQQQPQQQQQPSSPVEPNHQRSLRELMGQFSSKKRSGPQRKHQCRICQHAFTRPSSVDIHIRSHTGEKRKFQSSVVIATSILSVLLTPILLAFGCSVEGCDRYFSVLSNARRHERTHMKKEAAKAGLTRYDSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3R2</accession>
    <name>A0ABR3Z3R2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Biogenesis of lysosome-related organelles complex 1 subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000077">
        <property type="protein sequence ID" value="KAL1895173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06320">
        <property type="entry name" value="GCN5L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="329" mass="35297" checksum="6EC8FD3D8D7F50FB" modified="2025-10-08" version="1">MSSPPMPPSVTASRMNTIDSKPRYRPRRALVPSAASFATPTTSTIVVTTGSSNCKTSQSQSSLSTIASDTSAASMPFNTSNFTSAKSNSASSPTTLLPLRACSPGPQLHLQSYLHAHRQLRPSTPKASAQHIAAARAAVIANISNVIDPKLQDYAYRLHSGQAAIAGQQSKVQRATAALSRENDAVSRLVSEAERKVKELGSLRNWAEVLEQEMMVLECTVKIVRGEVEGWRDVESGDGRSSYGNEDNTDEESVVPEMDLPLAVKGLSKSFQSSQYAAPSAPTTNPTTRQYASALIPLYKGFSVASLAPANPAPRVSPMRSWYRTLLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3W2</accession>
    <name>A0ABR3Z3W2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2828 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003283</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000075">
        <property type="protein sequence ID" value="KAL1895326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058580">
        <property type="entry name" value="DUF2828"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011205">
        <property type="entry name" value="UCP015417_vWA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31373">
        <property type="entry name" value="OS06G0652100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31373:SF27">
        <property type="entry name" value="TROVE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11443">
        <property type="entry name" value="DUF2828"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2828" evidence="1">
        <location>
            <begin position="30"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="239" mass="26905" checksum="46AA9C1D82852680" modified="2025-10-08" version="1">MAITGAFSPSQKIKESPFCVSTPMGFVKSKHGKKLQSASHHSTECESRHGRAVHRFMHNARYCALHIAVACAFIAQLTCDLAALNSTDEEVKRSVSMCAKWAPSDFGFHDKQTVIVLTIAEAMYPESLFADEITADLEAAADPGKRRVWYLWLARDKYRRDISALPTLRNYIGVFLKRDRERFMNYVQELSEGKSQSRNSQDILSPGLLVKDQIDTLSRWNSRISGHGLNINKVINNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3X0</accession>
    <name>A0ABR3Z3X0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNA polymerase I-specific transcription initiation factor rrn5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000075">
        <property type="protein sequence ID" value="KAL1895329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039601">
        <property type="entry name" value="Rrn5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28079">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28079:SF1">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="417"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="419"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="584" mass="65629" checksum="1DACA80BE753F34E" modified="2025-10-08" version="1">MDSDASRDDLHIAQHNSPQRFLSPSKRKRASLEIGRFRPFKRRAGQLYQAYIDILNQNTEEARLRICLDPSLSAAKLSTTQIGCTIWSEHEKQVFFDATARLGRDNIAGIAGLVRSKSEVEIAQYIAFLDAVKDQRWQNNRLPVLHPTDIPAAVEISQPCVIALENAADAISLRQDQHEEAIEKRRWGENLWRVDSRVADELELEHRETCATEGAPFATLLRTDRFLQLARRIFMNAAVPEYNWEFVDDEEPSIRATALQDFYALVVSMTRRIVHTSLCVASGRIAAKSRGQAVQNVVRQRDVEAAVASMGLKDSKEFWATAPRRLRLKVIDDTVDADDLEREKDVEDSLYKSQVDAVGDAYGDCDNHETRGEFEAALKVMTYDEIESLLMPANPNDESAFIDSDNELYSSSASTLAADTKDGGEAEKSEESHESSEGDNVDEDDDISPTSSRQLSPFFPPSPPLPNQQITDDLDEIFAYTAVDFGNPHSAESVLLHRLRIEKAYEDAADAFDADAARTEECRLWEALGTTPPQDVVARNRERERERTTVLPSKGQATVAVSEMYSTGAWREHVDYVPEWEMGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z511</accession>
    <name>A0ABR3Z511_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Allantoicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">DAL2</name>
        <name evidence="3" type="ORF">Cpir12675_003268</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the allantoicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000074">
        <property type="protein sequence ID" value="KAL1895361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00813">
        <property type="entry name" value="Allantoicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005164">
        <property type="entry name" value="Allantoicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015908">
        <property type="entry name" value="Allantoicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02961">
        <property type="entry name" value="allantoicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12045">
        <property type="entry name" value="ALLANTOICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12045:SF3">
        <property type="entry name" value="INACTIVE ALLANTOICASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03561">
        <property type="entry name" value="Allantoicase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016516">
        <property type="entry name" value="Allantoicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Allantoicase" evidence="2">
        <location>
            <begin position="63"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Allantoicase" evidence="2">
        <location>
            <begin position="237"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="380" mass="42190" checksum="67BA1CBEA2C7B926" modified="2025-10-08" version="1">MSSLPLLTKPTSVEEQPEGSVYPLEDIPVKPIASGGIDKTFRSSSIGRALYLRYSDLISATLGGKILAFSDEWFAEASNLLTPTPPIRQPGKMVYTGAWYDGWETRRHNSEPFDWVVVRLGVASGTIEGIEIDTAFFNGNHAPWISVEGCFSQNDEEVISWKGTRGGWETIVGHQECGPSHRFSWKLQSPTKKPYTHVRLNMYPDGGIARFRLFGHAVPVFPNDPEAIFDLAAAQNGGVAVSCNDQHFGSKDNLLLPGRGKDMGDGWETSRSRTKGHVDWCIIRLGAPGYLERFVVDTAHFRGNYPQSVRVEALEWTSESEPEHTSSGWEEFVSASKCGPDKEHEFASLHKEKLVTHIKLVMIPDGGVKRIRAFGKRSTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5Z2</accession>
    <name>A0ABR3Z5Z2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="5">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ARO8_2</name>
        <name evidence="7" type="ORF">Cpir12675_002964</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>D-erythrose 4-phosphate + phosphoenolpyruvate + H2O = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the class-II DAHP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000063">
        <property type="protein sequence ID" value="KAL1896048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002480">
        <property type="entry name" value="DAHP_synth_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21337:SF0">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21337">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE 1, 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01474">
        <property type="entry name" value="DAHP_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="472" mass="52180" checksum="168AEBB19351B35B" modified="2025-10-08" version="1">MPEHINANTYPRDWSPASWRTKPIKQAPPYPDITAVSKATTQLKRLPPIVHPHEIAHLKGLLKDVAQGKAFLLQGGDCAELFDYCEPTAIESKIKLLLQMSLVLIWGTDKPVVRIGRMAGQYAKPRSSPTEVVDGVEMPSFRGDILNGYAVDERDIDPARLVSAYNHSAATLNYVRASLASGIADLHRPLDWDLGHVRDAGLRARYTEAANSITDMLSFLHTIGADRLDKLDTVDLFTSHEGLLLEYEEPLTRLAETPTSSPGKQTLYYDTSAHFLWIGDRTRQVDHAHVEFFRGIANPIGVKVGPTTPPEDIITLLRILNPAREPGKVTLITRYGATKVRELLPAHIRAVANSEYADNVVIWQCDPMHGNTLSTGAGVKTRRFSDIFSELRETLAVHQEMGSYLGGMHLELTGDAVTECLGGGAGLDEDDLSTNYTSFCDPRLNERQALELAFLVAEHYRKSRKPVAAGMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6H5</accession>
    <name>A0ABR3Z6H5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">37S ribosomal protein S35 mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000060">
        <property type="protein sequence ID" value="KAL1896258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021036">
        <property type="entry name" value="Ribosomal_mS45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28158">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN S35, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28158:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12298">
        <property type="entry name" value="Bot1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="344" mass="39437" checksum="4307B725C48FF9BF" modified="2025-10-08" version="1">MSVRLGTTALRAMAQASVQVSPMHRSSTITRHLSTSSSCAGRLDPMLRERGLRTLGRQDMKRFLDRLDSRWRERQSNGGNRSSGFYLGPHPDQPFPLNPQFRSQPVLSEPAREWIWRRVVQKGEALKVVSADMSVDIRRVAAVVRLKEVEKRWLQNGKKLATPYSEAIMSMLPQTQYFIPNNKNPQTAPHEPHEPINEIHTHGHTLQQLFWPVAESRAFTREDAASAFSPIMLTPERRSPHTELIDAEKAVTSNKMSRTEAMDMWRQRAEKNQADLNCRMEEKLKTDRACITSVHTDRFEFRFKDFNSENVGKLGRKRDAVGHKYGVPNYNRKRGAVKIPTSVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8B1</accession>
    <name>A0ABR3Z8B1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_002816</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000059">
        <property type="protein sequence ID" value="KAL1896412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF26">
        <property type="entry name" value="FAMILY HELICASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G09120)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="2090"/>
            <end position="2133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="34"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1472"/>
            <end position="1503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1896412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="2268" mass="255356" checksum="CE588E16BA43D216" modified="2025-10-08" version="1">MDIDLPPGKEVNTGSDGDAPINYILDYTIGETLDTAPRSPTSTTVSSQTLTNNGTLESSSPNPAAFAFQLPSAEFDRPPARTLQSVHDIFSVLMQGALDLGLSQVAEGGGVHVRVATLCSGTDAPIFALRELQEAAAALGYSNVVSFEHIFSAEIETFKQAFIRRNVKPHGPVFRDVQEMAKYDKAMNAEGFLEKVGHDVDILVFGSSCVDFSNLNNSKKALGKGALVDITKADYTEDEPEVQDFLESILDCVDGESSRTFLSGLLYISKYRPCVVIMENVINAPWDQISNFWFAKVGYVARYRKCSSKDYGMPHIRMRGYLVAVDYREFGEDSERPGDDRLLQYRTALKKTAKSLRINDARMCQLRHAEARAQEGLPLGSRYTMMDHRSHCMPREDSFQDSIVDMGEREKDLLDITYERGLQKQYDMNHKLLIYDISQNVDRAPGQLGWAPCLTPKGNPFVTNQGRPLLGIEALGLQGIDIDRIVPSIETQMQLQDLAGNAMTTTVVGAALLSAIIAIEGSWKKCFSRPARHYVNTLLDETRNERTPVIYQDSNITDLATTTQRRPDQLDSMSLEHLMTIFEDCRSYCSCESASVRRRSSSLLQCATCREIRCKSCAGNPRHHMFPKSTMKFEIREKHVAVELVRRLANHAFVLCDEDSLPGDLSAVTEPHIVIPSLEDMALDGISWDPDLERVMALCRSKVRLIFEKVHVGQVLTIFYQSVDVYLHVVIEGKTIRWLVFVKASSWIAREYDHLHDWSRPFLMAEVDLWRQRGVPEPHNWRFWLKDEIKATLSITGLVDGHYKLAFQEAQWFNSGKWKAVIRFHPFWARFVRLVQGEYSYSDECGVSRGRLMAKHSDNTASVYIFEDPGLVSAPEDDRWVVAWTNRRLHTFEVRDVLATLNSFPAAGAMPLNDGFDTAKVDIFVKGWWAGVPNPKPDPKKPVLSLRRQASRRYSDRASPFGGVLIHSKVFQPVVTKVRGTHSDMLSCQPTPFVTVRVAVDKLHWPNDLFPMLMRPGSLVFRTGVDQDGWLTLPQRLHTDAMQLIYHNFKAITEESLVNCLENGAGGIGMTRAALELCPVCTPPIPHVHGVVNPDGNIVDLISDQEECRHFEDCIRARPCPLQIQVRIVPGTLIDDEQQKSHIEVRVNLNIETLVHRASGYLPQPAYALLQPRSREGEVHIRADIETWYEEDDLWSRAPFIEEVWPTTAETSDVDVTSMAQPSSFVYNGKFLRTDQMISLGWMLGARNNNVKPFRECEIEECMVPGLNMRLIGEAGRDNYVRGGVLAHEVGYGKTVVALAMLDYTRKHNIQSLRDRSELVPNGLIHLKASLIIVPHHLIQQWCSEIDSFLQNSTQPWKVVVIGSKRDTMQLNRAELQKADIIVASFRAIQLGQARLDTLAVVGGQLRINEKESGRKLSNWYDAVISWIRPSRQDESRNKHKKNNKNPRRDYTVIDSLTKQHFQHTLYAVRQAQRTQVPHSSRRSTTANKKQGSGSVTKLDQSWRQSIEKPSKLWRDGSLLELYSFSSIVYDEFSYNEEHIALFFRHALATAKWILSGTPPLAHLGQICDMAGLLNVHVAREEPAIPPHMPKITQGPSTKDMSQAERFRSYRQLKSSAFVAERDEQARRFIHSFIRRNFAVQGKYSLVELVVPVTMNSVSSLLYHVAQQTLFDAKWVFDDVQGDIREMINAMSAPRVDRQGRPVPLSTKKYLTVAAEALMAYASGRATEMMQAMHTPAVKLEVGTNESQGQGQDRYNVQSLLHQLYNKQLMQVKLLCKLLKSQWDRMIYLSERLEKDPTFNMKTASATDPRKAKQSSAIKLRDSVVHSLFRSESVSEIQILLRQMVFGNKEPQPEILARLMDDRPVFAGCKWVAHEGGPAAFSVFDWYPKVDEALYHMDTTSSERAAIIGAALWAMKDPESAATPEAARQVQSEIADFVGTQLDSFSHESTLLLLENVRNRQDLFESTDQTEIDCGFTGPNIRQFHYCRTTGLKCTQHDTKAQLEAKLSRFAAGEAREADFEFQGTLPHLHPHYGQTKTTRGAPIDAGLDDFILTVQSLGRGIKNHFVPAFQRYRLLRLCINLTHGSPLNCDVCERQLPPEAKHRDEVFCLVTCGHAYCKHCASGFRVDEDYHCRVSTCRCASRGSLIDAKSLLPLDCYADSEASAIETSSKVTKVVTLASEIVQRGDSVLIFAQFDYLKDDIAAALTAAKIPYGRTDGQDGPDQLVAFQAGRFSVLLQSLMSTESAGSNLTIANHIIFAAPLMTDKYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8B5</accession>
    <name>A0ABR3Z8B5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">AMP deaminase</fullName>
            <ecNumber evidence="9">3.5.4.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">AMD1_2</name>
        <name evidence="9" type="ORF">Cpir12675_002771</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.6" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000057">
        <property type="protein sequence ID" value="KAL1896482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003876">
        <property type="term" value="F:AMP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00803">
        <property type="entry name" value="nst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778:SF4">
        <property type="entry name" value="NUCLEOTIDE SUGAR TRANSPORTER SLC35B4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08449">
        <property type="entry name" value="UAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="116"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="205"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="355"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="390"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="422"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="422"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1896482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="448" mass="48192" checksum="B0EDEA27A1A9BE3B" modified="2025-10-08" version="1">MSEKTDLDSSDPTLSSSAPVGVAALDEEKKPLIAPKSSEPPTASSEEDRSQDVPIFPTEAESQSGMTTVLVDFLVSSLSVLVVMAFIFGGCCSNVYALESIIKVEPESADTDAGTLLTFVQFLFVAVTGYISQFDKTQAPFFLTPNKVPKRRWLVNTVLFFSINVMNNHAFSYDISVPVHIILRSGGSITTITAGYLWGKRYSRIQVAAVLFLTVGVITAAYSDAQSKGKTEGSSGHSEFSMGLVILFVAQVLSAIMGIYTEETYKTYGPQWRENLFYSHVLSLPLFLPFLPSLIDQFSRLANSPPMIFSLPGWLISEASTSSVSALPVTSVSFPSQLVYLVLNVLTQYACIRGVNLLAAVSTALTVTIVLNIRKLVSLLLSIWLFGNRLAVGTLVGAIVVFGSGALYSLDSSGRRAAKPASTVTPVSLPPSQAVQKPTKQAVQKKIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8L7</accession>
    <name>A0ABR3Z8L7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Actin-related protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ARP3</name>
        <name evidence="3" type="ORF">Cpir12675_002634</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000053">
        <property type="protein sequence ID" value="KAL1896913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10221">
        <property type="entry name" value="ASKHA_NBD_Arp3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="40"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="439" mass="47982" checksum="71961C54D186190A" modified="2025-10-08" version="1">MANQTPAVVMDNGTGFSKLGFAGNDSPSFVFPTAIATKNSASGSGGTGSGRPAVANKPSFLTGGAGPSSHLNSKRGTEDLDFFIGDEAVAASGGPGYGLHYPIRHGQVENWDHMERFWSNSIFKYLRVEPEDHFFLLTEPPLNPPENRENTAEIFFESFNCAGMYIAVQAVLALAASWTSSKVHDRSLTGTVIDSGDGVTHVIPVAEGYVIGSSIKSIPIAGRDITYFVQSLLRDRGEPDSSLRTAQEIKEQHCYVCPDIVKEFSRFDRDRSRFIKHVVSHPGGRQSTIDVGYERFLAPEIFFNPEIYSSDFLTPLPVVVDNVIQSSPIDVRRGLYKNVVLSGGSTLYKDFGRRLQRDIKQLVDARIRASEVRSGGAKSGGLDVQVITHKRQRHGPWFGGSLLGQTPEFRSYCHTKAEYQEYGPSIVRRFALLGGPGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8N8</accession>
    <name>A0ABR3Z8N8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000056">
        <property type="protein sequence ID" value="KAL1896654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="150"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="183" mass="19532" checksum="0D57DF0519DEAB35" modified="2025-10-08" version="1">MSFHATHSFASHHHHHHHHRSATSRRSLSAIIGLPTNRPSLDEYLDSMLHPHPADVDASTPRPTSIYTPVVSGLTSVSVSSPAVSMPTPATLPFPPAQSTSANASSSSTFRYLNHLTTPPHYVVPNTIRGGGNTNNTNSQSSGDPALGRSSSPASSSPDSSRFLSDDDYDDDNRMSTSRVHGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9A0</accession>
    <name>A0ABR3Z9A0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000047">
        <property type="protein sequence ID" value="KAL1897248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046106638" evidence="1">
        <location>
            <begin position="17"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="381" mass="41132" checksum="2781925D3EF0244E" modified="2025-10-08" version="1">MKLPFLLVSLPILAAAVPLKNNQATSPGPKILAPALANDNSVDEFVQKTGQTGFPSPYAKELVPKGYKPLDSDIDFPPPNLLNADDKSHGAATVAKTKNDISSCDRQGSIPSDAHNVHAHGYCNLSSAANNFRRAESLGYNKIDVVPSFGNAEAQGYKKKVVPNSRRDEALGYKKADVVSKPSKAYLKLDASTNAEAPHLSRKGIYRPAISLKGPNDKGGKILALHSGELEVSAPVVSRTRARDIKYFVGEDDAGYCQAKTAQFYRLDFGPLARRGDCADLAEYLEREPGYFIATELNQLTPLAVMNSCYIQVIRKIGTSDTLRFTTSDAAAILRSFLEDYSGVSDSSVIHNAIGTTKCNGHYLGWSVTGAYNHTVSSESM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9C5</accession>
    <name>A0ABR3Z9C5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SGF29 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_002369</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000046">
        <property type="protein sequence ID" value="KAL1897265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20393">
        <property type="entry name" value="Tudor_SGF29_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20394">
        <property type="entry name" value="Tudor_SGF29_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037802">
        <property type="entry name" value="SGF29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010750">
        <property type="entry name" value="SGF29_tudor-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047288">
        <property type="entry name" value="Tudor_SGF29_rpt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047287">
        <property type="entry name" value="Tudor_SGF29_rpt2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21539">
        <property type="entry name" value="SAGA-ASSOCIATED FACTOR 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21539:SF0">
        <property type="entry name" value="SAGA-ASSOCIATED FACTOR 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07039">
        <property type="entry name" value="SGF29_Tudor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51518">
        <property type="entry name" value="SGF29_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="SGF29 C-terminal" evidence="6">
        <location>
            <begin position="287"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="111"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="133"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="223"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="238"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1897265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="425" mass="46827" checksum="CC4DA76C0B7FCE6D" modified="2025-10-08" version="1">MSQRNRSGRGSARNNGASHGEEVSLWELCREKINESIALVNEDNANLDKILALDSQAAEELRKDSQPAYRTLAKMEDLCRTGVKAEDTASAQIKSLIEQLTILRGVQSAKEQAATSDEKPTSLGPTSRAGASRTRDREREREQREREREREQERKRDRDHEREREREKERERDRTERAEREKEREKDRDKDRSTPVPAALSASATGGNTAVAAGSSLYEFEGGTESPVPSPVGGPTSRRAERAERNSQRDSIPPVVEDDRTPGPSDKGSGTPSAHGGAGSGSGVRAKPHVFAKGDAVAFKPKTAPGESPSDWILGEVKAVLGEGKSRRYKVLDVEPEPEDASSQKEYRSSASSMIPITAEAGVKSLPDWESGKKVLAMYPQTTTFYPAEVISTAEGGKVNLRFDGENDYTTMQQVERRFVIDFRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9E1</accession>
    <name>A0ABR3Z9E1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002384</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000046">
        <property type="protein sequence ID" value="KAL1897280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="280"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="347"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="412"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="659"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="739"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="222"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="290"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="451"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="696"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="758" mass="80004" checksum="E3AA4CAE5CF1B43B" modified="2025-10-08" version="1">MELSLVLPPRLTNARLTPPSPLPTNNSPLDQITNVLSTELDARSLSVPAAIIPSGLLSPNSARVLYAFIHYSYTEKYAVPLSILSNRRSLMTHMEVSIDVLAAATAAGNPGLADAAEAEFASLRSRLKDRDVLDVLSIKRGAHPTVDAELRALIENYHASPARAETLQTWVTLANAPSLCAAVSGAYLASRSELSAAVVREAAAMRQAAQIRADLDEERRFSVRMALQLAEMEARVQELELEREEERMKLMVEDMHRASQDHTQVERQMHEDGPISLCGTIGPDIGPGDVDLEGESEDDMETTDAVEAGKGKQEGEMHVVAGIHEMDGGSAVATAAASVDGRDCRAQPATAADITPTTIAETATETTTNSDALAPRKDSKPALANDPLDFTAETPPDPQHAFQDLALEPAATDESDFEEVVSIHSPSRPVEPPLAEPRPSSAAVEAQEEEASSRLEVDDTGKDRAKTGVKAEAQAEVRPDASTTQSTVDNIEDASADKPSEDVSAGLSTALHPTGPSTAAELERPALPPRPEPITRTSIATAAVTAAVTAVAAASPLPLLGTTPPCLNIFHREPRPEQPTTALSPITAAADSSPTTGPDAIPAPILVSMPVSVSPGSASCRPVSVPGGLPASPTGSLQLNADDADGAPVVRDYACQQTQQQLQHNLPPSPCPSPLLSTSPSARRVRKPRFFGMWTSAETPSTTSGNSLKADNTAPTEAENTALSQPQRTNSLMHIQMPAQAYTHVSETPRGPGWSPFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA72</accession>
    <name>A0ABR3ZA72_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF924-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002339</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000045">
        <property type="protein sequence ID" value="KAL1897483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.320">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010323">
        <property type="entry name" value="DUF924"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06041">
        <property type="entry name" value="DUF924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1897483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="283" mass="32018" checksum="518005D9ECE5891B" modified="2025-10-08" version="1">MSTYPSPSPASLARIQEIFTPELYSQVYDTWYNDLPHSSVVAPEATVKKWFGLLSPAENTALDELCTRRFKSALSLLLPDAFPLPEPLPNSHAEERRQDAHIAAPFFGTNSAFPTVASGGSNGGTGGLTDEEARNALGLIILLDQMPRNIFRANQAVIYNHLDRISRAVTYTFLSLKPNRRPDTQASISVSPIRRIFWYLPLMHSEWLQDHVRYSELMSECRAEIESKGQKEALDWVDMNSKSEEKHVSLLKEYGRYPHRNEHLGRVSTPAEQFFLDNGGTYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAE3</accession>
    <name>A0ABR3ZAE3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">serine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Seryl-tRNA synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Seryl-tRNA(Ser) synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">DIA4</name>
        <name evidence="11" type="ORF">Cpir12675_002277</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000043">
        <property type="protein sequence ID" value="KAL1897549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="entry name" value="Serine-tRNA synthetase, tRNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015866">
        <property type="entry name" value="Ser-tRNA-synth_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11778">
        <property type="entry name" value="SERYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02403">
        <property type="entry name" value="Seryl_tRNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="tRNA-binding arm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="10">
        <location>
            <begin position="233"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="24"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="140"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="24"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1897549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="557" mass="60787" checksum="57533C339F5933DA" modified="2025-10-08" version="1">MNALRFVALRRPIVATSRICSQHSPNSLRWTSSSTSTSTPSASTPEANSPLDAGRQLEDSSLSEGPTALPAAPSLVHAPGSLTPPQPVSPLRPIVDSKSIRNAPEIYAANCMARNYGKCGSYPARIASLHHMRLSMRAALMNLRTRARRFQDDMRGLTQEQRAEIAPHAQEAKKKLADHLKNEREIDSEIERLTLALPNLTSDETPRSSPRLIDYINAPAVGDVDPLASMSRSHVDIGAELGILDFASSAITSGWGFYYLLGAGAQLEQALVQYATQTAMAAGWTLVSVPTIVYSHIGSACGFQPRDTNDEQQVYSIEQHMAPKQIAAHEKAFAEGREPPKRPQHVLAGTAEIPLAGMHADSTLPLDQLPLRHVASSRSYRAEAGARGQDTKGLYRVHEFTKVELFAWTKPEMAASVAVFDEMVDLQRRILGALGLRCRVLEMPATDLGASAARKIDIEALFPSRRELAKSEGGWGELSSASICTDYQTRRLRTRVKAENGTVTFPHTVNGTALAVPRVIAAILETHWNEATRAVAIPEVLQPYMGGKMWIEAEKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAK6</accession>
    <name>A0ABR3ZAK6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cell cycle RNA binding protein whi3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">WHI3</name>
        <name evidence="5" type="ORF">Cpir12675_002483</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000049">
        <property type="protein sequence ID" value="KAL1897162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10501">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="550"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="70"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="300"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="368"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="652"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="725"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="71"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="307"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="370"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="668"/>
            <end position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1897162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="822" mass="82168" checksum="83B5CF994E83D5AD" modified="2025-10-08" version="1">MSDSHTQHCLDIQKNPSPASSALPSASPSASPSASPLRTVETSITNALVPDLSPAPAPAQASYTAPIAAPLSSSPVSDDMDNSSIPSSSTGAAINTPVGSLPSTSPVSNTAATSTNYMTGSSPSPTSYFVSPDNIPPPSTANLSGIMADSTALIDMQTSSGFDPAPQRPGSGPAISAAPVLIRIRHLPEFTTNDQVRFMLQFCADGDVVDVETRPADATTRDAGLATAHVTLRSRHVADDISHALDGKMNIRGTATLIIELASASNTPTQTFGRLRGRVSPAATSVSGIGNGLGAGAGASTVPNYSPGPGSSAGHSPGPGSAHIHAPIHATTTSSGGNATPAASSRASALNAADAATAAGPARYAFGTLPTGSEFPSRQTGKDLIGGSDANHDDDNELLSIPFNNGSNAFTNVSCNGSGSTAAAAVAAAAAASVSGMTPPPGSIPLIPAYGSLPPLSSQRRATVAHIPMLSALAGLTPLNTNLNGAMLFHPVTGPTSAISPLVGSSILSPLSNLGNIHGPFTAGPTPGPSFRRGSNFPSANPADQNPPCNTLYVGNLPAGTTEDELKEVFTAVKGYKRLCYRVKANGPMCFVEFEDIQHATKCLNDMYGYLLPRSNKHGIRLSFSKNPLGVRSMPQTNMPAATLPNLGGPHAVPAFPNANGPPPGLSMPPGLTLNSRSVSNNSSGGVGAPNAAGSGSGSGTAAAAATTTINTKLASEMSLLSTSASTTSAGGASSSASSSASPSVPAYYPASASTITANPWNSGLSVFGSGPGSGATGSSLFDAARGFGAFHSVQATEQAQAQAQAQAQANTALFPSHMMGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBV5</accession>
    <name>A0ABR3ZBV5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002227</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000040">
        <property type="protein sequence ID" value="KAL1897800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF16">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1897800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="127" mass="14473" checksum="E0797D9DB8515E1B" modified="2025-10-08" version="1" fragment="single">MLDDLSLGNAILIVDTLDECRIDQKQLLEFIAKPSRAKWIVSSRNWPDVEEILDDAEQKVKIHLEMNQNSVSAAVNSFIDAKVDQLAQKKKYNMEMKLAVSKHLRLNADNTFLWVSLVCQELSGSQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCF0</accession>
    <name>A0ABR3ZCF0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sphingolipid C4-hydroxylase sur2</fullName>
            <ecNumber evidence="8">1.14.18.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SUR2</name>
        <name evidence="8" type="ORF">Cpir12675_001948</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.18.5" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000034">
        <property type="protein sequence ID" value="KAL1898323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102772">
        <property type="term" value="F:sphingolipid C4-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050307">
        <property type="entry name" value="Sterol_Desaturase_Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11863">
        <property type="entry name" value="STEROL DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="7">
        <location>
            <begin position="201"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="357"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="372"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="411"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1898323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="439" mass="50845" checksum="46312C79F70EA9DF" modified="2025-10-08" version="1">MALPNATLLDELPPLPEYTLKSLPELFPGIVSDVTLVAILPVLVYWITSMFFHFIDVYDFWAQYRIHTPEEITSRNKVSRYEVARDTIMQQIIQMATSILLSVTEDAPTYGREEYDVAVWAQRLRRAQRGFPLLLNLIGLNAADISANMAQSHPLLAGVLAGGHYPSLTTQLNSHTVPTFAAWELLVGRLIHYVLVPALQFIVAVVWVDTWQYFLHRLMHNNRWMYNTFHSRHHRLYVPYAYGALYNHPVEGFLLDTLGAGIAYLVAGMTQRQGMVFFSFSTIKTVDDHCGYSLPWDPLQHISSNNAEYHDIHHQNWGIKTNFSQPFFTFWDKLLDTRYTGTRHIEQRMRVREAFEKKQHEKMEHHHHHHPRQEQQQEEQERGHEQRNLRLRRQSQQPFASDLGLLKRHQSSGQTQTCGHSCGQSTTLQPAVVSVSSQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCJ5</accession>
    <name>A0ABR3ZCJ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">5'-3' exoribonuclease 1</fullName>
            <ecNumber evidence="5">3.1.13.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">exo2</name>
        <name evidence="12" type="ORF">Cpir12675_001913</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the 5'-3' exonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.-" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000033">
        <property type="protein sequence ID" value="KAL1898368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18673">
        <property type="entry name" value="PIN_XRN1-2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12390">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027073">
        <property type="entry name" value="5_3_exoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016494">
        <property type="entry name" value="5_3_exoribonuclease_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041385">
        <property type="entry name" value="SH3_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040992">
        <property type="entry name" value="XRN1_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047007">
        <property type="entry name" value="XRN1_D1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041106">
        <property type="entry name" value="XRN1_D2_D3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041412">
        <property type="entry name" value="Xrn1_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004859">
        <property type="entry name" value="Xrn1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047008">
        <property type="entry name" value="XRN1_SH3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341:SF7">
        <property type="entry name" value="5'-3' EXORIBONUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341">
        <property type="entry name" value="5'-&gt;3' EXORIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18129">
        <property type="entry name" value="SH3_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18332">
        <property type="entry name" value="XRN1_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18334">
        <property type="entry name" value="XRN1_D2_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17846">
        <property type="entry name" value="XRN_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03159">
        <property type="entry name" value="XRN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006743">
        <property type="entry name" value="Exonuclease_Xnr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 12" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="1 5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Xrn1 N-terminal" evidence="7">
        <location>
            <begin position="1"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Xrn1 helical" evidence="8">
        <location>
            <begin position="276"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="domain" description="5'-3' exoribonuclease 1 D1" evidence="10">
        <location>
            <begin position="728"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease Xrn1 D2/D3" evidence="11">
        <location>
            <begin position="919"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="domain" description="5'-3' exoribonuclease 1 SH3-like" evidence="9">
        <location>
            <begin position="1234"/>
            <end position="1304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1150"/>
            <end position="1211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1348"/>
            <end position="1492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1154"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1176"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1197"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="1362"/>
            <end position="1379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1410"/>
            <end position="1419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="1470"/>
            <end position="1492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR006743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF18129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF18332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF18334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1898368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1492" mass="165629" checksum="F948E43DDAEE3844" modified="2025-10-08" version="1">MGVPKFFRWISERYPPISQLIAENRIPEFDCLYLDMNGIIHNCTHKDAGEDATFRLTEEEMFLRIFSYIEHLFSKIKPKNMFFMAIDGVAPRAKMNQQRARRFRTALDAENAREEAIKKGVEMPKEPAFDSNCITPGTEFMQKLSNQLKYFVNKKISEDSDWQRCDVVLSGHEVPGEGEHKIMEYIRNAKAQPGYNPNMRHCLYGLDADLIMLGLLSHDPHFCLLREEVTFGRASKNKSTELEHQNFYLLHLCIVREYLELEFCELAAPGALTFDFDLERVIDDFILMAFFVGNDFLPNLPRLHINEGALASMFRLYKQVLPKCDGYINEDGVINIPRLVKLVEELAKDENGHFEDDVANESWFQSKKMEESLGVGVKPNAGRRKAKQSSIVITRAQSELWKQRIKPYVQSRSKIPLNLGDSLPEADRKFVQDVADKLHMPWSTKENDKETRDLIMEFPPQADDDDEKSDEEEEGSVAVYRVIKQYDSAKVFDPIKENAAIAFEDIYKKKFQAWKTKYYLDKFKEWTPDNYETGLTALCVNYVQGLQWVLYYYYRGIASWPWFYQYHYSPLTSDIVKGINANLNFKKGAPFLPFEQLMGVLPDRSKSIVPSVYWPLMTDPKSPIIDFYPRDFELDMNGKKMEWEAVVKIPFIDEERLLSAMAPINETLPPEEAGRNTFGVALKFSYSATVNFVYPSSMPGHFSDIASCHCVENIFDLPSIEGIKLHAGLMPGAKIKAGALAGFPSLYSLPCSGVLVEGYGVNVFQSDSRNPSMIITLTDADNATKIEANKTKLGKRCFVGYPFLQEARIVQVSDEMFDYRLGPNGKINQYNHSDRQISEWSREASYIENWNSKRMGFEIGSVETLVKVEMLKGLIKTEKGAMVKEYAENLGVRSVYAAQTIVDEVGEEDGRFIEKEALPIEEEFPVGSKGFFLGEYSYGQPLAITGYNGTKANIRLSVKEKEPEFTQKIILDHTSHNRYTPAYAVARNLGINSLLLSRITSSYQIETVGGLRVNLGLNLKFEGKRQKVLGYSRKSTTGWEFSHVALDLITQYIISFPDFFAQASRHATSSDVTADQLWPDKETAQARVKEIVAWLKGIGIQKLNRVPLDAEQLDSNLVTVLADAGADLHARTEAQTEAALQAKAKAAAEAKATSEVNPAANNGTQDKDESAEAPTDASTNDGINGKANVNDTAGTVSASKKPTASSAPGVRLMQNVPRNAILKSIDAEATLSNQKFQLGDRVVFVASSGKVPLNYRGTVVGISRTATAVLLDVVWDVAFMGGTNLDDRCPGFRGQTVASWSVLNLTNKQLVFGSNAAIRRNPTASICLMGSDASGVAQYKDAPMPPALSDGWKSAVSNQNGNGRGGARGGARGGRGRGGPNEPQILHSSLVYRPHPDSEQNGRGSGGSGNNNYNNFNSGRGRGRGGFRGGFTNNGPVSQQSYNAVPPPNLDDTPRGSRGGSRNRGRGGRGGRGNGNRGGRGGRGGAGAPATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD76</accession>
    <name>A0ABR3ZD76_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">U4/U5/U6 small nuclear ribonucleoprotein prp3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">prp3</name>
        <name evidence="8" type="ORF">Cpir12675_001847</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000031">
        <property type="protein sequence ID" value="KAL1898643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd24162">
        <property type="entry name" value="Prp3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013881">
        <property type="entry name" value="Pre-mRNA_splic_Prp3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027104">
        <property type="entry name" value="Prp3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010541">
        <property type="entry name" value="Prp3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14212">
        <property type="entry name" value="U4/U6-ASSOCIATED RNA SPLICING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14212:SF0">
        <property type="entry name" value="U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08572">
        <property type="entry name" value="PRP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06544">
        <property type="entry name" value="Prp3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="domain" description="Pre-mRNA-splicing factor 3" evidence="7">
        <location>
            <begin position="55"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Small nuclear ribonucleoprotein Prp3 C-terminal" evidence="6">
        <location>
            <begin position="293"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="32"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1898643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="430" mass="48523" checksum="F958D9A1F4641406" modified="2025-10-08" version="1">MSSTAERMAALKARVAAAVGNSKGGLSVSLHPALEDLNGRPPSLKPANSGKQVPNKYLEQTPSQTHGFRAREPRKLEFNQKGKYIQQANAIRRQAALEQIKKRVAEQSRKAGLNEVPSDKSFVVEEPPAVEWFDQGYLAEGKTYADINDPACLRLDGEDSIITDLVQHPVPLEPPQDGLVPHAKPMFMTRKEQKKLRRQKRMADLKETQAKIRLGLMPAPEPKVKKSNLMRVLGEEAVQDPTAVEERVNRQIAERHETHVTINAERKLTKEQKHDKLAVNQEKDIAKGIHMLVFKIGNLASGQHRFKMWKNAEQLALTGICLVHPRTNLVIVEGGQYSTNKYKKLMMSRIDWTQSAPPPSAPANTHNTREWMTDDANSMASNTINLLFEGESKTRTFKKWSSKICDTDKEAFDFLSRVKLESFWVQARQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEF1</accession>
    <name>A0ABR3ZEF1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AP-2 complex subunit sigma</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Adaptin small chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Sigma2-adaptin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">IST1</name>
        <name evidence="18" type="ORF">Cpir12675_001737</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit apl3 and beta-type subunit apl1), a medium chain (mu-type subunit apm4) and a small adaptin (sigma-type subunit aps2).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <location evidence="2">Coated pit</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the IST1 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000029">
        <property type="protein sequence ID" value="KAL1898734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14833">
        <property type="entry name" value="AP2_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.60">
        <property type="entry name" value="Vacuolar protein sorting-associated protein Ist1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016635">
        <property type="entry name" value="AP_complex_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027156">
        <property type="entry name" value="APS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005061">
        <property type="entry name" value="Ist1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042277">
        <property type="entry name" value="IST1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11753">
        <property type="entry name" value="ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03398">
        <property type="entry name" value="Ist1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0168">Coated pit</keyword>
    <keyword evidence="8" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="17">
        <location>
            <begin position="295"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="179"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00034519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1898734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="437" mass="48694" checksum="8D635C7EE2F6CFE1" modified="2025-10-08" version="1">MAPPYLSYTTKLKVQLKLAIARLRMIQQRDDSLSKTTRRAMAQLLEQGKIESARIRVENIIRTDIISELHELLELYCELLLARVGLLEGLGPCDPGLEEAVHSLIYAAPKTEVKELQTVRTLLAERFGKEFVLSATTNSNGRVSPNVVKKLQVTPPREELVQGYLEEIAKAYGVLWPEKSPAKDAQSGDEDGDGDGGGGGSAEKALSKAEQEQLALSKVSPPADIGARSPLRIAPPKMSTDNVHPKVTLDSKELTGLAIKAKRPSAAKKPGPEGKVPDISELERSGITCSKSAAMLSFILIQNRQGKTRLAKWYVPYSDEEKVKLKGEIHRLVAPRDQKYQSNFVEFRNNKIVYRRYAGLFFCACVDTNDNELAYLEAIHFFVEVLDSFFGNVCELDLVFNFYKVYAILDEVFLAGEIEETSKQVVLTRLEHLDKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEX7</accession>
    <name>A0ABR3ZEX7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Phosphatidylserine decarboxylase proenzyme 1, mitochondrial</fullName>
            <ecNumber evidence="12">4.1.1.65</ecNumber>
        </recommendedName>
        <component>
            <recommendedName>
                <fullName evidence="12">Phosphatidylserine decarboxylase 1 beta chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="12">Phosphatidylserine decarboxylase 1 alpha chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="12 14" type="primary">PSD1</name>
        <name evidence="14" type="ORF">Cpir12675_001681</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H(+) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CO2</text>
            <dbReference type="Rhea" id="RHEA:20828"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="EC" id="4.1.1.65"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
        <text evidence="12">Binds 1 pyruvoyl group covalently per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.</text>
    </comment>
    <comment type="subcellular location">
        <molecule>Phosphatidylserine decarboxylase 1 alpha chain</molecule>
        <subcellularLocation>
            <location evidence="12">Mitochondrion inner membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Intermembrane side</orientation>
        </subcellularLocation>
        <text evidence="12">Anchored to the mitochondrial inner membrane through its interaction with the integral membrane beta chain.</text>
    </comment>
    <comment type="subcellular location">
        <molecule>Phosphatidylserine decarboxylase 1 beta chain</molecule>
        <subcellularLocation>
            <location evidence="12">Mitochondrion inner membrane</location>
            <topology evidence="12">Single-pass membrane protein</topology>
            <orientation evidence="12">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="12">Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.65" evidence="12"/>
    <dbReference type="EMBL" id="JAWDJO010000028">
        <property type="protein sequence ID" value="KAL1898929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004609">
        <property type="term" value="F:phosphatidylserine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03208">
        <property type="entry name" value="PS_decarb_PSD_B_type1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033177">
        <property type="entry name" value="PSD-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033661">
        <property type="entry name" value="PSD_type1_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00163">
        <property type="entry name" value="PS_decarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067:SF6">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 12 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8 12" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="11 12" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12" id="KW-0865">Zymogen</keyword>
    <feature type="chain" id="PRO_5044930872" description="Phosphatidylserine decarboxylase 1 beta chain" evidence="12">
        <location>
            <begin position="1"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044930871" description="Phosphatidylserine decarboxylase 1 alpha chain" evidence="12">
        <location>
            <begin position="568"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="topological domain" description="Mitochondrial matrix" evidence="12">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="topological domain" description="Mitochondrial intermembrane" evidence="12">
        <location>
            <begin position="178"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="29"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="29"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="113"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="185"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="375"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="440"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="568"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity" evidence="12">
        <location>
            <position position="568"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage (non-hydrolytic); by autocatalysis" evidence="12">
        <location>
            <begin position="567"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="modified residue" description="Pyruvic acid (Ser); by autocatalysis" evidence="12">
        <location>
            <position position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1898929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="612" mass="67699" checksum="0335B99CEB85E1D4" modified="2025-10-08" version="1">MVLSTPTANANPNLDFTGSLAANSDLASFNSTTSSNSTASRPSSSCSYHSTSTLTTATLTSSTTVCDPDEDPDAKMRPRVPLSGAGPVPMLKPHPLGPPSGGFAAASMRRQDPLQQQQRARRQSAASLRTRFFSTYAPRRLRFTKIKTAIRNTRRHWYRIPVGLGIGLLGMLQFYKLSRKQDQEREELLGDENRSPKRRPRIRPDGPWQVQVMSTLPLKAISRLWGRFNELTLPYYLRVPGFKLYSYVFGVNLVEVAEDDLHTYPNLASFFYRTLKPGSRPLDPRHDALISPSDGCILQYGKIEGNDIEQVKGMTYTVDALLGKNTPAPSFVSSRSPTSTTAEAVVSERDEDIIKRDEEFARLNGISYTLPSLLSGGSRGRAASTSADLSTPASKSTEQEVIDELALGERPWYQQLSGIRKTALFYAVIYLAPGDYHRFHSPCNWVVERRRHFAGELYSVSPYLQRTLPGLFTLNERVVLLGRWRWGFFSYVPVGATNVGSIIVNFDKELRTNSLTTDTAADRAAEEAAARGEHYSGFSEATYEAASPVLGGHALSRGEEMGGFQLGSTVVLVFEAPVEGENGEKWQWEVEKGQKIKMGQALGHIATKPKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF69</accession>
    <name>A0ABR3ZF69_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Autophagy-related protein 14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_001462</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000023">
        <property type="protein sequence ID" value="KAL1899346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018791">
        <property type="entry name" value="UV_resistance/autophagy_Atg14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15157">
        <property type="entry name" value="UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15157:SF5">
        <property type="entry name" value="UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10186">
        <property type="entry name" value="ATG14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="57"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="587"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="646"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="601"/>
            <end position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1899346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="681" mass="75305" checksum="3CDF0F18832BAD59" modified="2025-10-08" version="1">MAESRSVLLAENRKLRHLRGVYLRNLTFEPFAGITHDDSVLTLTKLKAKGKLRVTENGKLPHARSSDDLIGEGGRSGNNGKRRRSTSGLGVSTVAAFTAAASLSATLTIPGNPGPRAEATTSQQKNLQMIIGARLADVFFSLHCEGEAEPVYISEVIEKRMNFNFQFFDLKHHATAISRSPIFTLKLWTRRQNSSTWIYLLENQVDLRSLTFIPALENYHFPANALIFHLNDGCMYTFGVPSSLSLRSRQLKPVFTSSYAALMKLCTLENSIQDAQATQQRLSAQIDSTLSRRPQNLVALARERAERAAGYLEQQRRAVVNAKHRVQQLKQSIKKRSAAMEAGKSVQMRIEKDRQNAMGHLSASHKLLTSTKDQIHGQRRRICSDLSDIFQILQIPDAPPLAFQIHGVPLPNTVYDTSTSRGKTEEKLSAALGLVAQLVNILQFYLGVPILYPVNVFGSRSSIRDEISLLPDLSAQQTQGTQDSRTREFPLYLPRGGSTTTQFRFDYAWFLLNKNIEMLCGAQGLRIVDIRHTLPNLQYLLYVCSAGPDELPERKKGGIRGLWIGRQDGRVSSISSFTSLNITVPEPPNGASHSGAAPGSIGSNTSNTADCRRGSTGSEVNIRQREDLRRRTVGVRNTSSLVDIGSEEDSVAGSPQFSLPFDEGETKLTLRTKGMRENVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFA0</accession>
    <name>A0ABR3ZFA0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">NineTeen Complex (NTC) component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">CLF1</name>
        <name evidence="14" type="ORF">Cpir12675_001416</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in pre-mRNA splicing and cell cycle progression. Required for the spliceosome assembly and initiation of the DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the crooked-neck family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000022">
        <property type="protein sequence ID" value="KAL1899380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055433">
        <property type="entry name" value="HAT_Syf1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055430">
        <property type="entry name" value="HAT_Syf1_CNRKL1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045075">
        <property type="entry name" value="Syf1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246:SF3">
        <property type="entry name" value="CROOKED NECK-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23231">
        <property type="entry name" value="HAT_Syf1_CNRKL1_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23233">
        <property type="entry name" value="HAT_Syf1_CNRKL1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="10" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="Pre-mRNA-splicing factor Syf1-like N-terminal HAT-repeats" evidence="13">
        <location>
            <begin position="59"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="71"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA-splicing factor Syf1/CRNKL1-like C-terminal HAT-repeats" evidence="12">
        <location>
            <begin position="224"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA-splicing factor Syf1/CRNKL1-like C-terminal HAT-repeats" evidence="12">
        <location>
            <begin position="375"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="552"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="552"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF23231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF23233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1899380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="674" mass="80468" checksum="5CE0AA98A05BDD51" modified="2025-10-08" version="1">MESRGPPRVKNKGAAPVQISAEQLLREAVDRQEVDLKAPTQRFEDLEELHEFQGRKRREFEDYVRRNRMNMNNWLRYAAWEMEQKEYARARSIFERAMDVHPNDVQLFVRYIEAEMKTRNINHARNILDRAVTRLPRVDKLWYKYVYMEEMLGNIPGARQVFDRWMQWQPEEAAWSACIKFEKRYGEFDRCRDIFERFTVVHPEPRNWIKWAKFEEENGTSELVREVFGAAVEALGEMFVNEKLFIAYARFEARLKEYERARAIYKYALDRLPRSKSRELHAEYTTFEKQFGDRDGLENVVLSKRRALYESQLKETPSNYDVWLDLARLEESALDIDRARDVYERAIAQIPPVEEKRYWRRYIYLFIFFALFEEEIAQDIPRAHEVYKVALQLVPHKKFTFSKLWLLKAQFEIRQGDLAAARKTMGTAIGMCPKDKSFRGYIELELKLFEFVRCRQLYEKHIEWNPSNSQTWIKFAELERGLDDINRCRSIFNLAISQDSLDMPELTWKAFIDFEEEEGEYERARDLYERLLEKTDHVKVWVSYAQFELNIPEDDEEEDGAEDDSDEKVSDEAKSRARKIFQRAYKTLRDGEQKEDCVTLLNAWLSFEHTHGSDEDQDKVQKQMPRRVKKRRTAEDGTIEEFVDYVFPADDQQVKNLSGIMAMAQKWKQAGEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFD0</accession>
    <name>A0ABR3ZFD0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_001457</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000023">
        <property type="protein sequence ID" value="KAL1899341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14733">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051568">
        <property type="entry name" value="LZTR1/Attractin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46376">
        <property type="entry name" value="LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46376:SF1">
        <property type="entry name" value="LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="BTB" evidence="4">
        <location>
            <begin position="533"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="709"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="720"/>
            <end position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1899341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="729" mass="80255" checksum="0D39B9235778706C" modified="2025-10-08" version="1">MADPLRSIPVTPSGGASSPHHSHPHAYLLSDSNSAMDTSIPGSSSSSNTYVMSNSAAKTWPALTESYRPKVIRTDGQRPACLVNASVTYCGNNQIYAFGGFDQYTDEVYNHVLCLNLTNQQWRLVDNYGDIPGVRMGHTATLYQGDKLLVFGGENEHRTYLADLIIFDLKTAHWRKPQVNGHIPKGRARHAAVLHEDKLFVIGGITGRDNYVLDDICYLDLKTFTWSRSWRFVARFDHSAYIWNDRVWVFGGLSDAMDKSGDLWWLDLKGNPAFQSPPQIGAERRPTAGCANNRGQFSIPAAPVVGSSGYAANSRTAQVNPPSFQLKGYAPPAPGAISSLKFVSGGTIPLQSQGSHFHVYSAGTLLDFQTPAATMISNLCTLSALDLGSLRWQKLAQGNEVYKAGYRWHYCTMNEEGTKAWLLGCESDMEMGVSPTGLEEFLSDIMEIDLRRYGFLGTQAESEISHETRPAFTSRAICDKPSKGLGSDLATIFDSPPESGSGADFIVTATADEAEDVDMISTGTGPCDEQDWLATEAPVSPPIHVHRLILQARWPYFSRLYNSQMAEFHTKKMHIPEPYTVVRAFLLYLYTDSIMGGASEASAPALSTVAGLLVMSDMYGISHLRHLCVNRLGKELDVAHACIIWYSAGIANEDWLRKRAAQFCLEHWGRVVRSDGFMKLPRMALVDLSQEVDTEGRVLGGDEAELVEGWRGSRYGQSSEGDEDDDAPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFJ6</accession>
    <name>A0ABR3ZFJ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mannan polymerase II complex anp1 subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ANP1</name>
        <name evidence="4" type="ORF">Cpir12675_001672</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ANP1/MMN9/VAN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000027">
        <property type="protein sequence ID" value="KAL1899012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052086">
        <property type="entry name" value="Mannan_Polymerase_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083">
        <property type="entry name" value="MANNAN POLYMERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083:SF2">
        <property type="entry name" value="MANNAN POLYMERASE II COMPLEX ANP1 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03452">
        <property type="entry name" value="Anp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="393"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="393"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="439"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1899012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="459" mass="52719" checksum="C8BC4FF9FA92DE13" modified="2025-10-08" version="1">MMPRHHNGAFANGYPRGNTFDISPHRYQPRSSTPASRRRRNMVLRIVVSLVVIFAFAYYIWPNSGPASVLTLGLLSASNSLQVDSIKYYDLTATQGTARGWEREERILLCVPLRDAEAHLGMFFSHLRNFTYPHNLIDLAFLVSDSKDNTLSVLIQNLERIQADENEYMHYGEISIIEKDFGQKVNQDVESRHGFAAQASRRKLMAQARNWLLSATLRPYHSWVYWRDVDVETAPFTILEDLMRHNKDVIVPNVWRPLPDWLGGEQPYDLNSWQESETALALADTLDEDAVIVEGYAEYATWRPHLAYLRDPYGDPDMEMEIDGVGGVSILAKARVFRLGAHFPAFSFEKHAETEGFGKMARRMGFSVVGLPHYTVWHLYEPSVDDIRHMEEMERERQQREKEDQEKAKKAEKLKEDFGDANSQWEKDKTDMQDLANQEQEDGTDVITDEEDMPVAGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGJ6</accession>
    <name>A0ABR3ZGJ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein mL49</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">img2</name>
        <name evidence="7" type="ORF">Cpir12675_001500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL49 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000024">
        <property type="protein sequence ID" value="KAL1899307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.780.10">
        <property type="entry name" value="SUI1-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007740">
        <property type="entry name" value="Ribosomal_mL49"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13477:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13477">
        <property type="entry name" value="MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05046">
        <property type="entry name" value="Img2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="140" mass="15475" checksum="A1F2853BA86FB790" modified="2025-10-08" version="1">MLSILRSAHPAAALLPSFSATVSTAWSARTYATETIVVSDVLARDKPAVDPTQKTYSVLRTASKNLPVYLDQNRASKTFTTIIRRIEGSPQDLKKDLYQALELPAEDVKVNPVTKHIHAKVLAYSPFRHSSQDRILTPST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHF9</accession>
    <name>A0ABR3ZHF9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Inactive metallocarboxypeptidase ECM14</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Inactive metallocarboxypeptidase ecm14</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ECM14</name>
        <name evidence="14" type="ORF">Cpir12675_001707</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Inactive carboxypeptidase that may play a role in cell wall organization and biogenesis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the peptidase M14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000028">
        <property type="protein sequence ID" value="KAL1898954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03860">
        <property type="entry name" value="M14_CP_A-B_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057246">
        <property type="entry name" value="CARBOXYPEPT_ZN_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705:SF147">
        <property type="entry name" value="INACTIVE METALLOCARBOXYPEPTIDASE ECM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705">
        <property type="entry name" value="PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00765">
        <property type="entry name" value="CRBOXYPTASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00132">
        <property type="entry name" value="CARBOXYPEPT_ZN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M14" evidence="13">
        <location>
            <begin position="90"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00026187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00026213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1898954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="441" mass="49104" checksum="C3C7688DBE816AD8" modified="2025-10-08" version="1">MLLRFKISTAEEHKAFYDAANALLLDVWSVSSGHADVRVRSNDVKSLIGLLPETMQHGISTLSHDLSENIANTYPKAFLDQLRLSQNRNTAVSYSESVVTAITATNEVFFQDYQPLPARTSFEGREITGIRIGVNADLSDEAPRKTILVIGGLHAREWVSTSSVNYLAWAFATRYNKDHVVTKIVESFDIIFVPVLNPDGFEYTWSSDRLWRKSRQPTGSQDCHGLDLDHTFSFGWEGSSVMHKNPCSEGFAGVKPFEAIETLELSNWARNVTQDNSTHFVGLIDLHSYSQQVLFPYSHSCHVEPPNLENLEELAAGLTKAIRLSDGGMYTFASACEGSIAKSGPHLETGGGSAIDWFHHEMQAHFSYQIKLQDTGVYGFLLPREYIIPSGEEMFSALKYFGDYLLGNNGIEHPSLSGATKDSQDVLSATDNSELKLRHRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI01</accession>
    <name>A0ABR3ZI01_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001022</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000014">
        <property type="protein sequence ID" value="KAL1900338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="413" mass="45230" checksum="D1A2AE6116062BEB" modified="2025-10-08" version="1">MEGFPGSLNGFMLGSFTDSEASLPEGVSCSSIEDMHAQLQTAFDHECTPTRAKHTITTFQFPLDTTFHIPLDELKGLLAPQDENEPALLVPIAEQKILVKDAVLNQRPNSHSLQMLAAKYITSRIGNVDASQWVVKDAKWERLGWVFTCICVQSMEHWQKQADDMKENPVLAEFIHKEPEPILASELVSDIFALMAPTPISPIAAGRRRRRRRPQFVAICPDNQPISQENAKKKRETKKIVAQSSQKQAPNSDVSVGDLSVVLATVDPRERLSRRDAAQALLGEAGIDSTTLSEDQFLILSNQSPTLQQESIAMLKQYGAERLRIVYPDATSSVSPSQSTTENEAPSTPISETTASNSSPIKRKRGRPRKSKALSTSQGTIVSNTEDIAVAAELRASAVDVAIRASTEQGVCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI47</accession>
    <name>A0ABR3ZI47_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 11">Mitogen-activated protein kinase</fullName>
            <ecNumber evidence="2 11">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">tmk1</name>
        <name evidence="13" type="ORF">Cpir12675_000965</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="11">Activated by threonine and tyrosine phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="2 11"/>
    <dbReference type="EMBL" id="JAWDJO010000013">
        <property type="protein sequence ID" value="KAL1900383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07849">
        <property type="entry name" value="STKc_ERK1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 11 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 11 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="23"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1900383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="355" mass="41057" checksum="91CCBD52EA141D49" modified="2025-10-08" version="1">MSRTAAPNAAGSRKISFNVSEQYDIQDVVGEGAYGVVCSAIHKPSGQKVAIKKITPFDHSMFCLRTLREMKLLRYFNHENIISILDIQKPRSYESFNEVYLIQELMETDMHRVIRTQDLSDDHCQYFIYQTLRALKAMHSANVLHRDLKPSNLLLNANCDLKVCDFGLARSAASQEDNSGFMTEYVATRWYRAPEIMLTFKEYTKAIDVWSVGCILAEMLSGKPLFPGKDYHHQLTLILDVLGTPTMEDYYGIKSRRAREYIRSLPFKKKVAFRTLFPKSSDLALDLLEKLLAFNPVKRITVEDALKHPYLEPYHDPDDEPTAPPIPEEFFDFDKHKDNLTKEQLKQLIYQEIMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI90</accession>
    <name>A0ABR3ZI90_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000894</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="615" mass="68949" checksum="9C7C0923943E8831" modified="2025-10-08" version="1">MSSSLNSNTYYSTSYPIKTLFRSNTNMLHVPGEFDHDMEYNMDDHDHEFTTEFSNFDYPTVDVNKSVANREFSSLINASTALLNTASSNPVSGPPSPPPDGPGSSEFAPPTRPSSTPFPQIVSRQLLQFEKSDAKMANTTTDHEEKVMVQDGESSSVETCGFSRLPVEIHEEILDYVFGSQPAAQPCLAGGFNSIAASWNISTRRFTRRDISDLALVSRVWRDLVQSRIYRHIKLRGSVNAIIGADSWFTQHLYLASYIRHLEVWFPVFQPAAVANTTNSATAIVRIPPNYSPASDGSPRRPYIAPDSNCTLEDIFLMINRHLPSIKVLSLEGGDRRKAPKVQNQSSSSPSAIQGLVIPSVHTLVTRGQWNLIRKTEDFAFIVDRFPNLVEWHSSYSRQKSKTYITMGMLILPFFRMKIKVLNLRMESEYRRERACPPLFFHKVLTFAHVCPELGAIAKSLEHLTLKTIDITVKNICRFYEATPDGPSTGTGIQDALFIQYFEGLVISAVKCLAEATSVNYLRIRYVDLDSAVPPLNPYFLIKDNECSGVWSNAIVAELRKSRPRMTFPGLDSSCPVVRTNEDGVLVLNPDFKRAKVKSFKISNYAYIQQALSPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIG9</accession>
    <name>A0ABR3ZIG9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cyclin-dependent kinase 1</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">CDC28</name>
        <name evidence="14" type="ORF">Cpir12675_000924</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07835">
        <property type="entry name" value="STKc_CDK1_CdkB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF254">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="4"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1900456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="332" mass="37890" checksum="3CF1C4EECDA8782A" modified="2025-10-08" version="1">MENYQKLEKVGEGTYGVVYRARDLQNGGRIVALKKIRLEAEDEGVPSTAIREISLLKEMRDPNIVRLFNIVHADGHNLYLVFEFLDLDLKKYIESLPQSDGGRGKALPEGSSEVLRHMGLGPAVVKKLMWQLCQGVKYCHMHRILHRDLKPQNLLIDCDGNLKLADFGLARSFGVPLRTYTHEVVTLWYRAPEILLGGRQYSTGVDMWSIGCIFAEMCTRKPLFVGDSEIDQIFRIFNILSTPTEEVWPGVTSYPDFKPSFPKWKRDPNASLCKPLDSIGLDMLEQMLVYDPAGRISAKQACNHPYFEEYQQAIATQQQQQQPQSRTRASYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ12</accession>
    <name>A0ABR3ZJ12_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000834</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="173" mass="18799" checksum="DF7AC5FE61549D91" modified="2025-10-08" version="1">MFLPEILSFDSDNVFFAGISGGAMLLTGYFIPTFMHEFPSTGALLLCGAMPPQVPWVKTKEFIGNTRFHFQSTKNELGGLDDLITQTIDVFSDTATDMGVSDGLLDKLQTVNNDPKGGHCIFDNVDFYSSIKLMAESYPNIMQKGDGIVPGIGNVLDGTTTTILSFDRALKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKQ8</accession>
    <name>A0ABR3ZKQ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="15">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Cpir12675_000781</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="15"/>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF10">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 17" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045916515" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="17">
        <location>
            <begin position="21"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="18">
        <location>
            <begin position="21"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="251"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="267"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="290"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="341"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1900767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="374" mass="37825" checksum="D3FB55E088304493" modified="2025-10-08" version="1">MHFSAATLMAVVASLPSTLAHYNFDCLIVNGEVSQPYEFVRQTTNANSPVTDVTSPDMICNAGGIDDAIMAKTQTKTVAAGDELGFTINNELGHPGPLSLWMSKAPEGSTAATYKGDGDWFKVYELTTSSITAEGLQWATYNGGGAKNFTFTLPAAIPAGDYLFRVEHIALHGAGSAGGAQFYIGCAQLTVSGSATGSPAPVTKIPGVYTGSEPGILINLYYPSPTSYEVPGPATWPDACIDHTINLNGQASDGNCNGDDGSSSSGSGSGSGSGSGSGSGSSGSSAPYPTGTTPSNAPVGTGSSTKPTSTAGAPQSPVSNSNPVDGNATPTTPAADEYAKPSSTQSSSPSTNSKAPSTCARRRRARRAAQAARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLJ6</accession>
    <name>A0ABR3ZLJ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Eukaryotic translation initiation factor 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TIF5</name>
        <name evidence="8" type="ORF">Cpir12675_000532</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2-beta/eIF-5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11561">
        <property type="entry name" value="W2_eIF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045196">
        <property type="entry name" value="IF2/IF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002735">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016189">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016190">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001:SF7">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01873">
        <property type="entry name" value="eIF-5_eIF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00653">
        <property type="entry name" value="eIF2B_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00515">
        <property type="entry name" value="eIF5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100966">
        <property type="entry name" value="Translation initiation factor 2 beta, aIF2beta, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75689">
        <property type="entry name" value="Zinc-binding domain of translation initiation factor 2 beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="7">
        <location>
            <begin position="258"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="145"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="428" mass="47479" checksum="E3C4F227EDF8DE3D" modified="2025-10-08" version="1">MANINVNPDITDQFYRYKMPRLQTKIEGKGNGIKTVIVNLSAVAQSLARPGSHLIKYFGFELGAQTNIDPPDDRWIINGSHDTKKLQDHVYGFIVKFVLCKKCKNPETVVIIKDDHIILDCKACGQRTDVDLRLKLSSFVLKNQPKKGKKDKAERKAARRAKQQQAATGKDNGGSGAEDASENGSNDAEGADDDGDSSDQEFQKIKSTVNAATEDVEVKDDVWAVDMSEEAVKARQAQLPTEFKAKMTLGDDDDEDGEGGGNTIYNEFGQWVIDQAEAKSSIDDINSVDIYVKAKEMGIEKKHRTVLVLAQTIFDENIVAQIPKRASMLKQLIGESEKHMKALLGGTERMIGSKSKEDSEIISNTVVKVLQLYYLKDLISEDVVTKWGTKASKKYIDLPTSKKVRKAAEPFLAWLEEAEEESGSDDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLR6</accession>
    <name>A0ABR3ZLR6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP synthase subunit K mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_000667</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000008">
        <property type="protein sequence ID" value="KAL1901177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021278">
        <property type="entry name" value="ATP19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28074">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT K, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28074:SF1">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT K, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11022">
        <property type="entry name" value="ATP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1901177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="69" mass="7313" checksum="AF07DF4F56D8397E" modified="2025-10-08" version="1">MVAYYSIFGRQVGSHYLSMAVLGSLFGGVYLSSSGKKAPTPGVVPPINAANSDEADFITKFLAEAEKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM95</accession>
    <name>A0ABR3ZM95_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Tetrahydrofolate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ADE3</name>
        <name evidence="15" type="ORF">Cpir12675_000404</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00477">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01080">
        <property type="entry name" value="NAD_bind_m-THF_DH_Cyclohyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.410.10">
        <property type="entry name" value="Formyltetrahydrofolate synthetase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01543">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01576">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000559">
        <property type="entry name" value="Formate_THF_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020628">
        <property type="entry name" value="Formate_THF_ligase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000672">
        <property type="entry name" value="THF_DH/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020867">
        <property type="entry name" value="THF_DH/CycHdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020631">
        <property type="entry name" value="THF_DH/CycHdrlase_NAD-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48099:SF5">
        <property type="entry name" value="C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48099">
        <property type="entry name" value="C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01268">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02882">
        <property type="entry name" value="THF_DHG_CYH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00085">
        <property type="entry name" value="THFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00721">
        <property type="entry name" value="FTHFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00722">
        <property type="entry name" value="FTHFS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00766">
        <property type="entry name" value="THF_DHG_CYH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00767">
        <property type="entry name" value="THF_DHG_CYH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="12" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="10" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic" evidence="13">
        <location>
            <begin position="5"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding" evidence="14">
        <location>
            <begin position="142"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1901535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="939" mass="100382" checksum="E3690F17A4A89200" modified="2025-10-08" version="1">MATKIDGTAIAKSIRERLVVDILKHQETNPRFLPSLSIIQVGDRSDSTTYVRMKLKAAAEANIKCELIKLPEDVSEPELLHIIHGLNNDPSIHGVLVQLPLPNSIDEYAITSAVADDKDVDGFGTRNIGELAKRGGRPDFVPCTPKGIMTLLASTGVDLKGKNAVVLGRSDIVGGPISHILRNADCTVTTCHSKTVNLPEHVKTADILIAAIGQARFVQADWLKPGAIVIDVGTNFIPDSTRKSGQRMVGDVDYDAASAAASFITPVPGGVGPMTVAMLMQNVVEAAVSASAREKLRKIVPLSLKLESPVPSDIAVSRAQNPKQITTVAKEIGITAGELEQYGAYKAKVSLKLLKRLEHRKNGRYVVVTGITPTPLGEGKSTTTMGLAQALGAHLGHLTFANVRQPSMGPTFGVKGGAAGGGYSQVIPMDEFNLHLTGDIHAVTAANNLLAAAIDTRMFHENTQKDGPLFRRLVPEKDGVRKFAPVMFRRLKKLGIDKTDPNSLTEEEVRRFARLDIDPATITWRRVLDVNDRFLRGTTVGTAPTERGFVRETGFDISVASEVMAILALSTDLEDMRERLGRMVVASSTSGEPVTCDDIGVGGALTALMKDAIKPTLMQTLEGTPVFVHAGPFANISIGCSSIISDKLALKVVGTEPQDSDDTAGFVVTEAGFDFTMGGERFFNIKCRTSGLTPDVVVIVATVRALKAHGGGPNIVPGTPLDPVYKEENIEILRAGCSNLRKHIENARLFGVPVVVAVNKFNSDTDAEIAVIREEAISAGAEDAILANHWAEGGMGALDLAKGVVAASKKPKNFNLLYNLDPSVLFKERVETIAKKMYGAKDIELSKLAQAKMETYTKQGFGHLPICIAKTQYSLSDNKDLKGAPTGFTVSIRDVRLAAGAGYLYALAADIQTIPGLPTAPGYLNVDVDTETGEISGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMC3</accession>
    <name>A0ABR3ZMC3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CTLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_000434</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051350">
        <property type="entry name" value="WD_repeat-ST_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22838">
        <property type="entry name" value="WD REPEAT PROTEIN 26-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22838:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23627">
        <property type="entry name" value="LisH_WDR26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CTLH" evidence="5">
        <location>
            <begin position="171"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="391"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="603"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="662"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="84"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1901565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="708" mass="77277" checksum="C61044FB2801E3C4" modified="2025-10-08" version="1">MAAAAIDAPAPNAQVLGRRQRNSVDIDVQDSADPSPNQVVPVPVPDPETERPSKRHKPTSAPVSAMSPHDDSGASSSRSTGHSFNFQDSLKNGDSRNSLKIANIINGSSTPSSTPPTAPKSKYCGHDREEVTRILIQTLGDMGHEKIANDLAAESRYRLETPAVSDLRAYILQGSWPEAENLIDRASTHESPANRESNNLILKHDADKDSLIFQIRQQKFFELLESGNTGLALLTLRTDLTPLVKRSDESRLNFLASLLMCSSPESLKQKGDLPDTVEEARQKLLASISLSISPSVMLPKQRLATLFSNLIKIQTASCIYHTDTETPSLLEDHECSQDRFPNQIALELKDLSCDEVWQVKFNNAGTQLAACGKTGRLVIWDTTDFRVVQNLVLHETGIENISWSPNDRKLVTCSVDKTAKLLDATTGNTIRKLPSFAAEISSCVWAPDGQSFVISSLDNEMPLVTFNSAGDVISKWDKKHRVQDMCLSADGCYIVALSNCKCIHVYNRESTLLVNKYQLSFTPLSIATGSHPDQLLINSKLGEVHCVDLMTGVLLRMYVGHTASEYIIRTNFGGANEGYVVSGSDDKMIYVWHRSTGVLIERLSGHTQRANSVCFNPKDPTMIASCGDDGVVRIWTNLYNKPILIAAHEAIVPDAVQEGSLNGHTRLGNGSDSASGSQGSLNRSTTNARNGLSRGSSRSWANGSIDSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMP2</accession>
    <name>A0ABR3ZMP2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000783</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540">
        <property type="entry name" value="TRANSCRIPTION FACTOR (ACR-2), PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540:SF5">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="678" mass="74594" checksum="98D5A2A9D0CB6425" modified="2025-10-08" version="1">MAGFQFIVTDNRGQTRRDDRRTIRSQCMKGKNKKHKPHDASDSALGGVDLEVVAGAQIQAPENPAIAPQSRPKSRCKPKPRARTGRRRVVSRKISPIPASAVLSTSSASASASATQPSHYSPSSVIFYASSPSGSRAFSPRSFSPRRSPSRSLPSRGSLSRNLPYRYSPFYGLPPVNATSPTDTDSSAGSDTALAIRTRTALSPSSPTSLTDREYKAYRAHSPQLEAAVIAAVSAQAPKGALGQDVQLAQFADMLDAVGHETIHTFFSVAHQIVYPASIFVDFSPSNTVWFSWLFEDAAYLHASLALMIGVRNVLNGRPHGRNVVTHVTKSLRALHARIAHDSATGDSLSTSNSSVAVVLSLIVVADMLQDDQSAKSHFDGLRRMVSLRGGLDDFLENAKMHIKISRFDLNFALDHGSCSQFTSNPVSFASMTPRPLLPSSPLIFNPSPLFPTSDRPPSASIGITDGRLTTVFEDMFLLSTRVNLVHDSLAPKLTDGEFQQYLSSVQYRLLQLDSNTLCTHDKCLRLCLLAVLATTYPLPNTRLRYPYLARNLRITLDAILPVSASPEGMAAELRADVDRRELLLWALLIGALAVFDVDGRTWMHALWRSLEPPREWDQMRFILERFVWFRPLHDVVGRKCFDGLWAASDALDSLSYTYQYYDDILPSIETDGYEVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN43</accession>
    <name>A0ABR3ZN43_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome b subunit of succinate dehydrogenase, Sdh3p</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SDH3</name>
        <name evidence="9" type="ORF">Cpir12675_000307</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03499">
        <property type="entry name" value="SQR_TypeC_SdhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="entry name" value="Fumarate reductase/succinate dehydrogenase, transmembrane subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014314">
        <property type="entry name" value="Succ_DH_cytb556"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000701">
        <property type="entry name" value="SuccDH_FuR_B_TM-su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10978">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10978:SF5">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01127">
        <property type="entry name" value="Sdh_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="Fumarate reductase respiratory complex transmembrane subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="228"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="267"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="284" mass="30907" checksum="84B8A04A8CC34D7F" modified="2025-10-08" version="1">MMATFRVSPDVDTVHVRFTLPISSGSLFQTRCSFAVVTADTAIRAGILSGTSLYRRPLAPSICDSTDPIPHLSKPIPTSNYAITIALRTMATNILLYLLASMRPSLGLTQNRLPQILLASAMSTSASRLSLSAMVSPAAVIEKTSIAQSQEILDAQRLHRPVSPHLSVYSPKQTFFTPSIWHRMTGSILSGSLYAFSTAYLAAPLFGWHLESASLVACAAGLPLAVKGGLKFFFGFPFVFHFINGIRHLTYDVLLGFSKPQIKKFDVLIWSSSTVVAAYLAFLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNJ1</accession>
    <name>A0ABR3ZNJ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">BAR domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">GVP36</name>
        <name evidence="1" type="ORF">Cpir12675_000325</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07600">
        <property type="entry name" value="BAR_Gvp36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018859">
        <property type="entry name" value="BAR_dom-cont"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10455">
        <property type="entry name" value="BAR_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1901635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="352" mass="39221" checksum="EFB6343D4613E917" modified="2025-10-08" version="1">MDNFKNLGQTFSSFGAQITPFASRTFQYTKEQLGQAEDKTQLPPDYIDLEKRVDALKQVHQKMLTVTYVNYPQTNKYYSLSLSMCALPLTKRITSNSSQYSNEAYDYPPNIKETFQDLSRTVGEKVNLLSTATSPAEAQAALVAPPSAKPQPKTFNHAIARSSLSSSQLLHQQHTGAGEDPLATALEKYALAMERVGEARLAQDAQVQSHFLAGWTTTLNTNLKFAMRARKNVENSRLTLDAVKARVTGATWKLPVTGTQREPVDENELSPEAQEEIEKAEDEFVTQTEEAVGVMKNVLDTPEPLRNLLELVTAQMDYHKKAYDILSELAPIIEGLQAEQESAYRQNRESAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Y977</accession>
    <name>A0ABR3Y977_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Retrotransposon gag domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_007009</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000555">
        <property type="protein sequence ID" value="KAL1884822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005162">
        <property type="entry name" value="Retrotrans_gag_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03732">
        <property type="entry name" value="Retrotrans_gag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Retrotransposon gag" evidence="2">
        <location>
            <begin position="83"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1884822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="311" mass="35118" checksum="90EAAE3D3D008A13" modified="2025-10-08" version="1">MDIEVTPVYTPAPPRSQGFPQFDGNKGIYRIWKRQMSAMLLLHEDTDVTRVVAAMQVALMGEANESAGGELQRLAEKAGSTVAEVWKVLDDHFEDPLFRARENKRLENLEQGNKTLDRYIFQYRDLLQQAGGDGYPEDVKIRGLMRGINDDLYERMVTIPTSPTLTSQIESLRGVSQLMEEVTQRKSRKRKPTLFTQPVKIDEGDPMDIDVNVSQVRGGPQRPVRGSEPGLPTGNAYRGKTSKWVSREVLQARKEAGVCLRCARSGCLVRVCPMKPARNPNRQVTRTNNMNTMREAPLEPLEDVCEESEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFD1</accession>
    <name>A0ABR3YFD1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Inositol polyphosphate-related phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006758</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000369">
        <property type="protein sequence ID" value="KAL1887005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046985">
        <property type="entry name" value="IP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200">
        <property type="entry name" value="INOSITOL 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200:SF240">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE 5-PHOSPHATASE C9G1.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00128">
        <property type="entry name" value="IPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inositol polyphosphate-related phosphatase" evidence="2">
        <location>
            <begin position="795"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="226"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1161" mass="128094" checksum="B6E82EFA4C912675" modified="2025-10-08" version="1">MSSAAVDDEGLDGTPIKSVSSLRSRFENMGKFEPAPAPPPVANPAPVVQDLPQPHPPRSMSPTAKLDWPRDSKPNDLLPPPTRLRETPPVSSLRTNNQQELPMRSSSPRAPPRPPVVNIQPPQSPPKKSGATGLPDPSNLLNPDSSSAPITSLRSPNQSFPEQRKTPRATGSKPPSPPPPRRSSETRRPPPPPVNRADKPAVRPKPVLSDSNGRLSALDKVPEVAPTKPKTSPFSSPPGSAAGGEDDGPPPMPSRPRPEPTANLTLIRSRSLHVGSSFEPPPPPLHPASAGRRRDREDMTTPKPMIMRQLTGPSASTRSPSIIEPPPLTPRRPHTVMSTKPPPPRPPRPHAPSNSDATQRIQNPHPLPHFQRPPVRGHQSHHSVVESHTYAEARTPTSQTHLPPPPRITPAVATTNNNSGTISTFSAPLAVMATSAPVQTEPNTIIAAYPDIYNVNRQPPFLKPGIPEITTKYDARVFDVCGEYVACGGSMTRAWSMFDGSELLMLPHAEGIRGTALAFKPAANPDDEGTKLWVGTNFGEIQEIDLDTKDVVCSKPGAHGRHEVIKIFRFQNQLWSLDESGILQVWGPDKSSVPNLSNSPSHTYRLPRGHTFSLIIGGELWYASGKDVYVFAPTLDGSSQCQLTPNPMCYDGAGEIVSGATIRSDPDKVYLGHSDGKVSVYSRKDYSLLSVASLNAFKINTLGGVSDKLWAGFNSGKIAVYDVTTTPWTMKKEWHAHDNPVIKLIPDAASVYRMGRFQVVSLGADNKLRAWDGLLKEDATEDYMRSVDTEYCDFDELDVHVLTWNAGASTPSQIQHSTDSAFFTNLIKDSGCPDILVFGFQELVDLEDKTATAKRLFKSSKKKDDKKDMSHAYRDWRDFLQRSLDDYMPSNQPYYVLHTATLVGLFTCIFVKASLRDRIHDLYATDVKRGMGGYHGNKGAIVIRFMIDDSSLCFVNCHLAAGQTQANSRHNDVAAILEGQILPIERNAAIRPDHYVGGGDGTMVMDHELCLWNGDLNYRIDAMSRDTVVMAVKNNNLGKLLERDQLLVAKRRNPSFKLRAFHEMPIEFAPTYKYDVGTDNYDTSEKKRSPAWCDRLLHRGHGRIQQLEYRRHEVRASDHRPVSGRFKFYVKEIDHTRKAATSARCAAVLDDIRISMEEEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFS5</accession>
    <name>A0ABR3YFS5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006769</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000371">
        <property type="protein sequence ID" value="KAL1886998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="455"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="522"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="583"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="915"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1380"/>
            <end position="1429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1457"/>
            <end position="1477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="539"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="587"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="646"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="915"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1388"/>
            <end position="1401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1414"/>
            <end position="1427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1886998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1477" mass="159293" checksum="D6BE20D48A298C01" modified="2025-10-08" version="1">MANSGLPEGWESDYDGKRWLYRYTATGAVQYKWPQPGDEYPDFVDSAIDTMDPEDRLASQQMGKMRKPAEGRKTYDSRMSATGGPLGFYNNEEFGNIEFFQPDALMYMGPGAYTDISPLGGDDFEQPLPDNVAELPNASANVGVSPLASERSTPKPANASMSGRPQTEGKFIDGGFVMSAIELASTTPVGELPSTNTVSPPVISMEKPPAPLLPPNIAPDECEFPMLDGREIQSDTRRFTGFYDPVGLVAEMPTEFTCISKEESAPIELGDHRTLASIERTAAQIPDIPELCSAPVDQGKDRREEEKIYRQQIRAQQRPYGDCQYPFQPQHDVIDPLPVSYRPKEQANSVPQSPQASNPTAAGPKYQPFTPGAVIPPKRTSTNEKHPQRGSIITGSGAFEGKDLVRPSSVPPVLRAMPPVFQPSPPAKPPVVSNGLIAQHRVPILPNLNDIDQNRQPPLVLRPGVPVSNSHPLGDDTPKALPVPDEKPERVLPYPDDDHEYDLGQSLSRPLQSISHIRDHRAASFPTVHRRTNEGNGIPKSSYNPMQSDPDSPVDDQELAALQSKSNPTQSNSFRPINTPAISRVESAPATTPTSVPSTSISQEQNGACPLPSFNNRVARPKSQGPPHNGGSVSPPFLTLQKGLPPQSNLPTHQDSSPGQTDRRANKKIRRHSIGIPMAAPTSVESRTAPGESLASARALRQPASSMHLAPRADSFSSRRPSVPESVPEHPEEDQTPSELPALGPSRLSSNLAIDCQLRRHSLGMSNEVWRQRIPGNRRSPLSFQGQTLLDPVTLPHKPKPDTQTKNTRARPASAFIMGRPLPQPKANAMVVPSRNESQLTTQQSGVPQSQSDLTVADCFVNTLSGSILHPHINDRSTAELPTHINPVSVSPSAQNLSAQERSFGRRLSVGLSTKVSHSLNDPPNASQVATSPSISRQVTAPSTGRPVSMPPIPRVSTFSSTTVNMTTIPQPQKFLKLTPVPKRPEPVTEVKEKGGWLSRLFRGSKRKSVPSSSFRVLSLPQLSPVLAEPPTADTIEPIAKPKLRPETRVEYLSQERSMTPKAPVLDIKERNLQDLTLSDHQDGLQGIASVTSAEKRPEQLHVSQSIKDVSHSASTNAPNFPTGEKAAVLPMKSLARNDASGELPVSTKSINGLSQPISLIVNSVGYDILGTPTASSEGVSRTYSGHSKTQSIAISDPGIFDVGLDSMSDQASVSTMDISEAQAQPILRPQLIEVSAPALVKVSASASKTFPISADNVAEQNHGLISPLNLKKSDRTFLLESFVPVKCDPKRLEQCNNISAQPDGVLEKTPAIRNSRSVILEAELMDALLSYGKNRASSERNIEPAGGSLLPDVRFEAKPLPCVQHGLFVAPLSTPRIRSTSGSSFGPALSRPLSPASSSAGVDMGNRIDDLGATNSSPSMPLQGQENGPALPMISGCLHSLFVETTHISVGIPSHEDRAWKKSPSPDYSGGDWEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG43</accession>
    <name>A0ABR3YG43_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Hsp90 chaperone hsp82</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">HSP82</name>
        <name evidence="7" type="ORF">Cpir12675_006763</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000370">
        <property type="protein sequence ID" value="KAL1887000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16927">
        <property type="entry name" value="HATPase_Hsp90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="entry name" value="Heat shock protein 90, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00505">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019805">
        <property type="entry name" value="Heat_shock_protein_90_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003555">
        <property type="entry name" value="PRK05218.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110942">
        <property type="entry name" value="HSP90 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00298">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histidine kinase/HSP90-like ATPase" evidence="6">
        <location>
            <begin position="25"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="215"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="672"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="216"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="679"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1887000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="700" mass="79573" checksum="F852A151EAD8F102" modified="2025-10-08" version="1">MSETFEFQAEISHLLSLIINTVYSNKEIFLRELVSNASDALDKIRYQSLSDPSVLDSNKDLRIDIIPDKENKTLTIQDSGIGFTKADLVNNLGTIARSGTKQFMEALTAGADVSMIGQFGVGFYSAYLIADKVKVISKHNDDEQYIWESSAGGTFSVINDTEGPQISRGTKIILYLKDDQTEYLQESRIKEVIKKHSEFISYPIYLHVQKEVEKEIPDEEAEETKEEESDDKKPKIEEVDDDAEEKKPKTKKIKETVNEEEELNKQKPIWTRNPTDISQEEYAAFYKSLSNDWEDHLAVKHFSVEGQLEFRAILYVPKRAPFDLFETKKTKNNIKLYVRRVFITDDATDLVPEWLSFVKGVVDSEDLPLNLSRETLQQNKIMKVIKKNIVKKSIELFNEIAEDKENFDKFYSAFSKNIKLGIHEDAQNRATLAKLLRYNSTKSGDEMTSLSDYVTRMPEQQKNVYYITGETINAVSKSPFLDSLKDKGFEVLFLVDPIDEYAMTQLKEYEGKKLVDITKDFELEETDEEKAAREAEEKEYEALAKVLKDILGDKVEKVVVSHKLTGAPCAIRTGQFGWSANMERIMKAQALRDTSMSSYMSSKKTFEISPKSTIIKELKKKAESDGENDRNVKSIVQLLYETSLLVSGFTIDEPASFAERIHKLVQAGLNIDDEDEETTAAAATDAPAVETGDSNMEEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG89</accession>
    <name>A0ABR3YG89_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_006590</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000330">
        <property type="protein sequence ID" value="KAL1887326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38166:SF1">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38166">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="196"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="414"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="424"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="435" mass="48341" checksum="3D1B2107A9BD33B4" modified="2025-10-08" version="1">MERRKFPSHGLASNLSEGWIPHPHKPVVVTEVDSNDASSSGGGEQLNAGQESGYNTHVLDYGTSTGTAEAEFPGGTTWPGHSYLHHDQNCPSTSDHMTEKPDQSLDTSIVTVVNRYATNPQVQQQQTMMSRATIPVPGSSAIPGALIDSCDTEIKLACPYFQRNKNGPRLERSCAGPGFPTIPRLKEHLYRRHMCFVCQRCGTQFEKPSHLANHTSENPPCEPNSVQPDLELGFGRDIEKKLRAKKRNMQWRDIYLILFPTDEPSTIPSPYYSTEVDDGIRNYQAYLERVTLDQLPRVIRDKFVGLDEEILSHISLEMPHIVNRILASASRQYVSAPNMDTETFQAIQSPDLHEQHSHSVPSQSPVTHAMSRTNIATPDFPLWRAVDTHSAEGIEPPLVYPMEDGSASEATHLGRSLPEMGNFPSGNNNWGQPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGR3</accession>
    <name>A0ABR3YGR3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">H(+)/Cl(-) exchange transporter 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_006523</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000314">
        <property type="protein sequence ID" value="KAL1887506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03684">
        <property type="entry name" value="ClC_3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3080.10">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="ClC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45711">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45711:SF3">
        <property type="entry name" value="CLC CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0868">Chloride</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="355"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="422"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="458"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="496"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="536"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="593"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="620"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="314"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="890"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1887506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="890" mass="97729" checksum="22565BC3DE252AD5" modified="2025-10-08" version="1" fragment="single">MPDLDPEASKGPTSADIAGSSSQQQHQSTQISFRLPPGSATPQPTVAQSRPLPRPYPMSAQPSYLAINTNSDGISDETTPLLTGRTRIRIHSGNATPYPRNGPPSWSQGLSGSLRSFRNHSRQNSWGQSLVDALNDREESDLRRQNFADERVWYDQFTSTDWVRDSIKDAYRVKELRARKGLGGRLHRMYDASQGWILSAVCGMLVALFAYIIDVSEALVFDFKGGYCNTHWYYSQARCCGHIGASCSEWKPWNEVLIHEAIDHEWIEYIVYITFVVALSAIACFITLWTKTVIPSAYQLATLDENLAAEQVPTPQQATEDSFSPQQTSKTEPTSSLPPMVYYSAAGSGVAEVRVILSGFVLHGFLGLRTLLIKTLALVPSVASGLSVGKEGPYVHIATCIGNIACRLFPKYDMNDGKRREALSAAAAAGVVVAFGAPLGGVLFGLEEVSYFFPAKTLFRTFFCCIVAALSLKFLNPYGTSKIVIFQVKYSEDWKYFEIGSFIFIGIIGGALGALFIKASKHWAKSFRRIGFIKAFPLSEVVLVALVTGIMNYWNMYTRLPVSELVFQLASPCEDDEDDSGLCPKAIEQIGPIMLNLLTALLIKGFLTVITFGIKIPAGIYVPSMVVGALFGRVVGHVVQWSVIRWPEFGMWSQCAATSPVSCIQPGVYGLIGAGSMMCGVTRLSVTLVVILFELTGSLDYVLPFSLAILVSKWTADAIEPNSIYDLLTAMNSYPFLDNKHKPIFTGELAQIIPPIRQWRVIDITDSPVVPATILRQKLELLHHAGELDGGLPIVRDKTLVGLIPAPDLEYALDSLPDEAMSQCLMARIVSIEDSDGEDMGADPTDFTPYIDPAPVSLDIQSPMDLVYECFVKLGLRYICVLKDGHYAGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGV1</accession>
    <name>A0ABR3YGV1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucose-repressible protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">GRG1</name>
        <name evidence="2" type="ORF">Cpir12675_006495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000310">
        <property type="protein sequence ID" value="KAL1887560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020100">
        <property type="entry name" value="Glc-repressible_Grg1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38789:SF1">
        <property type="entry name" value="GLUCOSE-REPRESSIBLE GENE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38789">
        <property type="entry name" value="REPRESSIBLE PROTEIN GRG1, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G14210)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11034">
        <property type="entry name" value="Grg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="69" mass="7171" checksum="8E026E555E3889E5" modified="2025-10-08" version="1">MDSIKNAANYVAESVQGATAGTSKEANKQVAKDSNSGLGTRAQAAKDAIGDKMNESSHNTKAEAYKQNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIT0</accession>
    <name>A0ABR3YIT0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">non-reducing end alpha-L-arabinofuranosidase</fullName>
            <ecNumber evidence="4">3.2.1.55</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_006316</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides.</text>
            <dbReference type="EC" id="3.2.1.55"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan metabolism; L-arabinan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 51 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.55" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000281">
        <property type="protein sequence ID" value="KAL1888059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010720">
        <property type="entry name" value="Alpha-L-AF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055235">
        <property type="entry name" value="ASD1_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051563">
        <property type="entry name" value="Glycosyl_Hydrolase_51"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31776">
        <property type="entry name" value="ALPHA-L-ARABINOFURANOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31776:SF0">
        <property type="entry name" value="ALPHA-L-ARABINOFURANOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06964">
        <property type="entry name" value="Alpha-L-AF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22848">
        <property type="entry name" value="ASD1_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00813">
        <property type="entry name" value="Alpha-L-AF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047483445" description="non-reducing end alpha-L-arabinofuranosidase" evidence="8">
        <location>
            <begin position="16"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-arabinofuranosidase C-terminal" evidence="9">
        <location>
            <begin position="452"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1888059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="637" mass="69334" checksum="8376E6CEF967733C" modified="2025-10-08" version="1">MRLHTILAFVASVAAVDITVSSSGGNKTSGHQYGFLHEDINNSGDGGIYAELIRNRAFQFSDAFPVSLDGWASVNSQLSLQNVEPPLSSALPTSVRVTPASGASTAGLSNDGYWGMSVKKQRYIGSFWVHGGYKGSFNASFVSALDGTLFGSVSIESKSVEGSWTEHEVNFVPTLDAPNSNNTFVITFETAGLAGSALDFNLVSVFPPTYKNRQNGLRTDLAEVIADIKPRFFRFPGGNMLEGITVATRWDWKQSLGPLKDRPGFPGVWGYQQTNGLGLLEYLYWAEDMGMESVLAVWGGLALDGTNIAEEDLQPYIDDALNEIEFVVGPETSTWGARRAALGRKEPFKLDFVEVGNEDWLEGGTAGWEAYKKYRFPMFQKAILAKYPTMTIISSGATSNGYPDIPQPALGDYHPYMTPDDLVKDFSRFDNDAIGHIVGEVAAVHPNGGTGWDGPIRERPWWIGSVGEAISLIGYERNADRVRGSFYAPIIRSLDRYQWPATLVQFAADPALTTRSTSWHIWHLIGSKQLVNTFPATKEFDPLFYVAGVSEESTMVWKGAAYNTTDGKPVPVRLNFDGVNQGARATFTLLTGPSDSYGVNTATENVVKTSTTTLTAGAGGVFEFDLPQLSVALLETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKG0</accession>
    <name>A0ABR3YKG0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Xaa-Pro aminopeptidase</fullName>
            <ecNumber evidence="5">3.4.11.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Aminoacylproline aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Cpir12675_006207</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.</text>
            <dbReference type="EC" id="3.4.11.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase M24B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.9" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000265">
        <property type="protein sequence ID" value="KAL1888352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01087">
        <property type="entry name" value="Prolidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007865">
        <property type="entry name" value="Aminopep_P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052433">
        <property type="entry name" value="X-Pro_dipept-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226:SF1">
        <property type="entry name" value="XAA-PRO DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05195">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01011">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminopeptidase P N-terminal" evidence="13">
        <location>
            <begin position="12"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1888352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="464" mass="51962" checksum="C5EAF185D91B646A" modified="2025-10-08" version="1">MENYESILKGKYPAKAHAKRVAEYIRNKRGGDSNAIFYIEGRQTKLLEDNDEPELFRQRRAFFYFTGCELADCFYIYNTATDHATLFIPPVDPDSVIWSGLPMSREEALDKYDVDAVRFSTELDSVLADCVKTCPTLHVIPHTVSIAAIKSASVTHSFTVNESILHEAVDNCRVVKDEYEIALIKKANVISTTGHHEIMRRAKTVGNEQQLEAVFLERSVAHGAKRQAYHSIVAAGRAAATLHYVKNDQPTKGKLNVLLDAGCEWDCYASDITRTFPISGRFTTESRAIYDIVLRMQLECIDMLKEGVLWDDVHLHAHKVAIEGLHDLGVLRGDKAAILDARTSVAFFPHGLGHYLGMDTHDTGGNPNYSDSDTMFRYLRVRGTLPAGSVVTVEPGVYFCKFIIEPYLKDDKHRAFIDEQVLAKYWDVGGVRIEDNLVITKDGSVNLTDTAKQVDEVLVLVNGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKK9</accession>
    <name>A0ABR3YKK9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Polyamine transporter tpo5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">TPO5</name>
        <name evidence="7" type="ORF">Cpir12675_006176</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000262">
        <property type="protein sequence ID" value="KAL1888417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF26">
        <property type="entry name" value="OS04G0435100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="382"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="410"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="449"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="481"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="537" mass="57303" checksum="BBA8F3696D3D8C9E" modified="2025-10-08" version="1">MTDLPRSEAGPSTTAINDRSQLEQFGYEQELNRSWGLLQNFGVSFSIISVITGLTTLFGYGLANGGPAVMSIGWLVISVATISVATAMAEVCSALPTSGGPYFWAALLAPPKWAPFMAWLTGWFNFLGQVAVTTGISFGLAGLISTVITVKNPDFQPTEAKTIGIYAAILLSHGLVNTFGSHTLRYLNNFSILLHSVGVTSICIAVLVKAPSHQNASFVFGRFVDGTGVDGHEGWGDRASPAYVVLIGALMSQFTQTGFDASAHLSEETHNASWSAPIGVVSSVGCSAIFGFFVLLSFLFSIQDLDRTMDGPYGQPVLQILVDCMGEDGAVAVFSIICLCVWHCGLFSITSNSRMMYAFARDGGIHSFFDNVNSSLKVPVRAIWLAILLAFILALPSLGSTVAYAAATSIATIGLYISYGLPVMAGLIWHNEFKKMKGPFNLHAFSRPVGIVCCLWIALITIVFCLPNANPVTTETLNYTPVAVGILLAGTLGSWVIYARHWFVGPSLEIQDAIRAMNTSSLPSAPEKSVSSDVNTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMF4</accession>
    <name>A0ABR3YMF4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_005951</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000234">
        <property type="protein sequence ID" value="KAL1889033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="528"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="129"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="235"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="355"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="493"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="556"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="14"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="263"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="298"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="355"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="630" mass="67102" checksum="42999DD4ACA87636" modified="2025-10-08" version="1">MASPELSPGGMEHGTSNISTNNPESQRAPSKSVAFELLINDGSQYRARLPMRVQIYPHDATESIVTTVKNFYGLYAGPTGSKGVSFEDEQGNTLIASFENFKHNMVVYVRVIEEAPHYGPYHRGPEYYGSERFPLQPPAHLEPAQKLSRSNSPASHSRRSASAATNRSSGNKKSGSRFSSSRTNYNQNGDYDGYSSEDGSTSTKARDQIGNTEISLDNIVEGGRRRKAKFESSELPLFAPPQMPAAPSNSSVSPTRRMDSHRNSISFSNGSQNPFTNTRPLQSPQSYGYGPNFYGTPSADTKTANQSLYGPHGTPNGMAPTPDPTVGSCISDEDKDVAMQLMRLGDVSNISNISNARTSASTQDDTYSGQADQMSSTGATSDCDSDGENGQPPIRRQRLDEIGSSRPIDGAAEIRAAPSVDTGGLTNLAPVSSPTKIRAPVLPKAKAMAAPKAKGVAKINKAPKVLGSVPKSKKTPAIASIASAMPGVLAGVQMSPSSLPPSRKQSISSLSGLAPGDDEHPDLSTKPRCQRCRKSKKGCDRQRPCGRCRDAGLSADQCISEDEGNGRKGRYGRHMGVPIKKEDVSAPPLSTPIQTPVPIPTNGIAGIGLLPPASIESSLSALDKNKKRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNM5</accession>
    <name>A0ABR3YNM5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_005744</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000213">
        <property type="protein sequence ID" value="KAL1889527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1889527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="305" mass="34587" checksum="5A36A2A8AC1ED591" modified="2025-10-08" version="1">MKSHKPASTSTAPSSTVDRPKVLRIKFPAPKPIVTVTSSISNLITETANRTAPTASIIVPVSRRKVKIAPFPFLDLPPELRLEVYRHFFKDVWRSIDLDPDNHRLIHKKLGLFRSCRTVRYEASDYFYSSRVFRVFPCHPGRYFKTKKPLLARMKPTCRAHMTTLEVRLGPGWSQPPRGWVVNDALGLQDCTKVYKIKIFVECDPGESVFKGFRQENGFFEAFSTNLLTDVINRLPNARMVEFDAWESVKKDGHLMQVLVGAMEALGMEITWGPERGWTSCQDHGNGKDGEAGLESQFAMLRMAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR18</accession>
    <name>A0ABR3YR18_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA replication checkpoint mediator MRC1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_005239</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000171">
        <property type="protein sequence ID" value="KAL1890814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024146">
        <property type="entry name" value="Claspin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018564">
        <property type="entry name" value="Repl_chkpnt_MRC1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14396">
        <property type="entry name" value="CLASPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14396:SF10">
        <property type="entry name" value="CLASPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09444">
        <property type="entry name" value="MRC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication checkpoint mediator MRC1" evidence="5">
        <location>
            <begin position="898"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="30"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="307"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="467"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="720"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="800"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="877"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="980"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1054"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1167"/>
            <end position="1198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1242"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="36"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="55"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="117"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="167"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="195"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="266"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="316"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="339"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="475"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="536"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="720"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="800"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="880"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="890"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="905"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1000"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1066"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1082"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1170"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1251"/>
            <end position="1266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF09444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1890814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1291" mass="140899" checksum="71DBFDD6DDC90D73" modified="2025-10-08" version="1">MASQSPSPERSSPAPIYRGLTGRSRLNALLAGHDSGSVHEDGDLEPAKPTRKTTRIASMSPLDSSSGSEDEIVRPRGRFAAQMMAQATAGSSSDDGSDDDVGLTAREKLRRQLLKPSMEEKRPEKKPDKSGDDDSDASNHVPTIKRRLKPRASTPDAQPVSTKMMDDNDDEDDDPAADEEAVAAMAKNPRLQALLERKRKERSAREAEEAAQRSARQANIESDDDDVDGDVAMDDIDDDVQDSTGNATKQPPRERASKQARQASKKAMEDIHRETQRIQRNMQLAHEVKTRKKFDKKNLFAMFDFKPAGDDDEEEETRKTYDKNREKQDVNKGEAAVATSPNKTTSTAAPAAPDINRANENAITIPNAASDRSTKKPTRQVKIPDLKLESITLDDAEIEIVDYSNDRVSKIAVPIEKMEPGMATLLQFAGKDEGHLVRLMKEKAEADLRRKARLQAKREHESRIKLLKSKGIHVPTEEEREREAEQVEDILARAHEENDRIRKRERERAKKNGEAIDQDRLLDDDSGDESFYGSSGDEEEEEEEEGAALELSGSEDEEAEEEEEEEEAKAMEGPVIENDDDDEQIIIASRRPKKKNAQVLSDDEDEDKGASVAPVTSDDPNKAMQTPRPKAGLAFAASAGNQSPAVPTSILRSATKPFIPGLPVTSPTKLDLAEMFAGTFNGSQDPDAVIPTFDGASMPDFTQDAFKMLADSQPDIIMASQGSDSQLKSQGMSRKGQTEDESQGVETQGLVNNFSLRFSQAGDSFSTLDEQNSALSQLSNMQMTQDQGLDFVEPLKERFVTAEPPRRDESIVPESPVPEKKAKSRLRSKGEVLAAQGSARESPPIPASHKTGVEVAEDAVDEFGFGTRSTADVLKEAARKQRKAEKKAKKLAEAFDRKKSKANEMVDDQAEESDDEYAGLGGVDGDFSSDDDSDAASVEEMIDDETKASTADERKLAAFYNERERVAEEAQVQKLYKDITTGGLRRKRGTNYDLSDSESDGERQRRMKRRQFDKMQRELLANERLRKTAEAPGNEAYMRAIVDEYAPDENSIIEMDMPDLDPAENGVSQEAPTSGPETLPLRKAKSRKQRKPQTLQDVRSQLTGLLDDPYERAAVLRDKLSGDATDNGDDDAIEVAGTPGSSIDTSAIAGVPPLRRAGSQVIDRLSLKRSASTHSTGSATSANGRMAFTAPGSSQSRTRSLLRGATSSLISSGMANAAAGPSGVTTGGGMGDALPMRKGAVKGSGLSGFSRENERRAALAETEKKREAKKLKGAGKRAQAIGGLFGAGSWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRD4</accession>
    <name>A0ABR3YRD4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">mRNA 3'-end-processing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">YTH1</name>
        <name evidence="15" type="ORF">Cpir12675_005381</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 12">Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the CPSF4/YTH1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000182">
        <property type="protein sequence ID" value="KAL1890487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045348">
        <property type="entry name" value="CPSF4/Yth1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23102:SF24">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23102">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14608">
        <property type="entry name" value="zf-CCCH_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 12" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0677">Repeat</keyword>
    <keyword evidence="8 12" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 11 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 11 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="14">
        <location>
            <begin position="39"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="14">
        <location>
            <begin position="77"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="14">
        <location>
            <begin position="105"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="14">
        <location>
            <begin position="134"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="14">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="11">
        <location>
            <begin position="39"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="11">
        <location>
            <begin position="77"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="11">
        <location>
            <begin position="105"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="11">
        <location>
            <begin position="134"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="11">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="217"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="239"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU369008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1890487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="264" mass="29730" checksum="5C0F35C17BD60870" modified="2025-10-08" version="1">MATSTSTSQLAADVLANNAPAYSFNFSPFLRLTHHHGLPADRPICKSYAAGTCPNGTKCLERHLSDPNARTTGPTGGLNSLVCKHWLRGLCKKGEQCEFLHEYNLRKMPECNFFSRNGFCSNGEECLYLHIDPQKRMLPCPHYERGYCPLGPDCSKRHLRRTICLFYLAGFCPEGRRCTLGVHPKWNVNLERPTRMADKLLKDEALAAQRRAEMEREEAEKARMGGGGYDREDITGRGGFRHGMRGRGKWRGRGGGIGHRRGQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRE9</accession>
    <name>A0ABR3YRE9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005365</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000181">
        <property type="protein sequence ID" value="KAL1890502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047406032" evidence="2">
        <location>
            <begin position="17"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="214" mass="22826" checksum="25C4DD95AF7C2B04" modified="2025-10-08" version="1">MKPSVVFLVGASTASATSWLSWPSWLSWESWPNKGSDPRPYSGLDGPENPAVPEVTVMIESLNLSPETMTGAVTIGIDCANGNLPATSIVPPLTFTPTSFITTTTTAPPTITDASVPQDEDGFEDISLVGRKRARVGDVDGNGRPWIEYAANLYSTTDAPAATGAGRGFNVPTADVENESSNEDWPEMFEMDLSEDDIEDDMDSTKAQASDDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRM1</accession>
    <name>A0ABR3YRM1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">poly(A)-specific ribonuclease</fullName>
            <ecNumber evidence="5">3.1.13.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">POP2</name>
        <name evidence="16" type="ORF">Cpir12675_005135</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>Exonucleolytic cleavage of poly(A) to 5'-AMP.</text>
            <dbReference type="EC" id="3.1.13.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.4" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000164">
        <property type="protein sequence ID" value="KAL1891009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039637">
        <property type="entry name" value="CNOT7/CNOT8/Pop2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006941">
        <property type="entry name" value="RNase_CAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10797">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04857">
        <property type="entry name" value="CAF1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="13" id="KW-0804">Transcription</keyword>
    <keyword evidence="12" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="18"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="119"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="496"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="119"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="503"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1891009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="560" mass="63238" checksum="09D06A90B11D2308" modified="2025-10-08" version="1">MPPNMRFNNGPMQGTYHAQQFQQHSQQHHPGTNPGYIGSNGQLNTFSGIPGNNIAMNTAANFSMVDPSRIGYPNGNFQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHVGQHPSQQQQVQHAQTTPQQHVTNQQHQHQHQHQHQHQQQAHLNANDYSHTPQVRNQSNKGRIREVWNYNLHEEMGVLRSLIQKYPYIAMDTEFPGVVSRPMGNFRGKSDYHYQCLRTNVDMLKVIQIGITLFNEDGETPPPRLSPDDLDPLVPVKLPTTGACPYSWQFNFQFSLRNDMYNEKSIESLQTAGIDFNALERDGIDPQDFAALLIPSGLVCFNDVKWISFHGGYDFGYLTKLLICEALPNDEVDFDRLMKLYFPATYDVKHLMKHAIRTQNSNSQTPLDPTTADILLKFEHKSGLENIADTLKIKRVGSAHQAGSDSLLTGKVFFQMRQRIFRGDISEEHVGKVWGLNIPDNAFGMPTISHMAGNEAGANGNQGQYTHTGNGPSTPNATHATLANTTPSRQQTHGVNGMMASGQNTPGGSFGHFAMPAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRW4</accession>
    <name>A0ABR3YRW4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005282</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000176">
        <property type="protein sequence ID" value="KAL1890682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018809">
        <property type="entry name" value="DUF2406"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28186">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 9 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28186:SF1">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 9 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10295">
        <property type="entry name" value="DUF2406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="309" mass="34833" checksum="81BDD0580E1119B5" modified="2025-10-08" version="1">MASYDQQYQTAAPHNQAYNPHNQHQNSPQQQNQYQSHPQEQYYQQQHQHQDYSSRPSNIQFDRQVTETPQAPSHESTAAHQRKHSRGFSLSSNKAGSRKSENFETPAEKESHRLHTKADPSLAMNEAEPAAIAAMQATSMPSLRSIQHKDPFGNPIVEPDVSNPTRSRWERPLDTIRNFEAAIDGNYSTRPNYVPPSKETWVKRASIYSNPRDGNRSSYYGNSNNYSDSQQRPRNAPAAYPSYQTTGSGASGEHDHTGSEISSSGGQNYSHNNYSTQNAPQTQLSTVTPVAAPAPQEKRKSWFKKTFRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS08</accession>
    <name>A0ABR3YS08_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">DBP2</name>
        <name evidence="13" type="ORF">Cpir12675_005276</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000175">
        <property type="protein sequence ID" value="KAL1890696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17966">
        <property type="entry name" value="DEADc_DDX5_DDX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8 13" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 8 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="12">
        <location>
            <begin position="140"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="171"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="374"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="529"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="7">
        <location>
            <begin position="140"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="44"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1890696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="549" mass="59611" checksum="F5B233F3E32CA231" modified="2025-10-08" version="1">MSYNEGGYNSGPRGGNGGGGDRFNDRGGGGRDRGFDRQDDRRGGYGGGYSGGGGGGGGGYGGRGGRGFGGGGGGGGGDRMGGMGAGLKQQEWDLSAMPKFEKHFYKEHSDVTNRTDEEIKAFREKHSMAVVGTNVPKPIETFDEAGFPRYVIDEVKAQGFPAPTAIQSQGWPMALSGRDVVGIAETGSGKTLSYCLPAIVHINAQPLLAQGDGPIVLVLAPTRELAVQIQQEISKFGRSSHIRNTCVYGGVPKGPQIRDLNRGVEVCIATPGRLIDMLEAGKTNLRRVTYLVLDEADRMLDMGFEPQIRKIIGQIRPDRQTLMWSATWPKEVRALATDFLSDFIQVNIGSLELAANHRITQIVEVVTESEKRDRMIKHLEKIMDDKSNKCLIFVGTKRVADDITSFLRHDGWPALSIHGDKQQNERDWVLDQFKTGNSPIMVATDVASRGIDVRNITHVLNYDYSNNLEDYIHRIGRTGRAGAMGTAITFFTNENSKQARDLVNVLKEANQQIDPRLAEMTRYGGGGGGGRFGGGFRGRGRGGGGFRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSR8</accession>
    <name>A0ABR3YSR8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SNF1-interacting protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SIP3_2</name>
        <name evidence="3" type="ORF">Cpir12675_005072</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000161">
        <property type="protein sequence ID" value="KAL1891137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024500">
        <property type="entry name" value="DUF3074"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40370:SF1">
        <property type="entry name" value="DUF3074 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40370">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11274">
        <property type="entry name" value="DUF3074"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3074" evidence="2">
        <location>
            <begin position="99"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="514"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="359"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="531"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="559"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="592"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="627"/>
            <end position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="793" mass="86207" checksum="AE7541AEEC81D871" modified="2025-10-08" version="1">MTSQAIFHVLEPIEWDDISPHSADFTDILDDTIFHGRSIIASLPAAAAPPAKIPLGGHVRLMVEGLRREWKEVKGASGKDDQLGIAVYRLPAADNKGTWFGRRSVDTRVPFDRWKDAFMAEFPEALRTGQVIRGLSAQEQLEDLATDGCHVQVLRMGAQFPGPTAPRDFVAMVLTCESSALSASTQSATATSDATATPTSGRLLRELIVVSKPCDHPASPAVHGTIRGFYESVESIREIEGADGHIAVEWTMVTRSNPGGNVPRFMIERGTPSAICGDAVKFYKWMETVDLSAYEHPPETATKRQGGLLTNSSETLATEKAVPTAAAAEHDSRHAFHSLYPTAQQHNHNHTYHNSQYDSSHLSSPPGSSRRSIQSMRSIADTLEGPPPTFKATCNGTPSVHCSYDSDDDDNESFISALSEPEHFTPSPPSPRRPSSIHSYNHTPERLSTDAPMAIHNGYLSPHRANHTFPIMKAHGTDSLATPTRLSAEWMASTEEIAAAVANSQSKDRLRNHLQNRRQSAHMHSTSMHTPHTKAPRRSQSHHRPRRATTPSASSNQLAASPQRQYAASASAASISSASGSSSRSRSRSDSKSSAAPNSISGSSIKKEHRSLADRLLHRTPSKSKAARKEAERQRKQEAKARRAAEKREEREMKQGIRARHEEEKKARRAAAAALKTQKDASHKRQSSSEGSMGKENNYGTSPVETRPGRAAGTESVPRSVAGGLGSARPMSAVVPGAAAAEDPRVLKLERDTLKEQVVQLRNQNAMLAGRLGQLGLEDDEIKRLAALAPKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUX3</accession>
    <name>A0ABR3YUX3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Plasma membrane proteolipid Pmp3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PMP3</name>
        <name evidence="7" type="ORF">Cpir12675_004644</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0057 (PMP3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000136">
        <property type="protein sequence ID" value="KAL1892176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000612">
        <property type="entry name" value="PMP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659">
        <property type="entry name" value="HYDROPHOBIC PROTEIN RCI2 LOW TEMPERATURE AND SALT RESPONSIVE PROTEIN LTI6 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659:SF42">
        <property type="entry name" value="UPF0057 MEMBRANE PROTEIN ZK632.10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01679">
        <property type="entry name" value="Pmp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01309">
        <property type="entry name" value="UPF0057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1892176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="57" mass="6215" checksum="3192B1834E427B98" modified="2025-10-08" version="1">MPFTASDICKIILAIILPPIGVFLERGCGADLCINILLTILGYIPGIIHALYIILKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV45</accession>
    <name>A0ABR3YV45_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Store-operated calcium entry-associated regulatory factor</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Transmembrane protein 66</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Cpir12675_004651</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SARAF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000137">
        <property type="protein sequence ID" value="KAL1892143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009567">
        <property type="entry name" value="SARAF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15929">
        <property type="entry name" value="STORE-OPERATED CALCIUM ENTRY-ASSOCIATED REGULATORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15929:SF0">
        <property type="entry name" value="STORE-OPERATED CALCIUM ENTRY-ASSOCIATED REGULATORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06682">
        <property type="entry name" value="SARAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 16" id="KW-0732">Signal</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047208467" description="Store-operated calcium entry-associated regulatory factor" evidence="16">
        <location>
            <begin position="19"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="151"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="257"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="273"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1892143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="282" mass="29680" checksum="53DEEB1A38187A9D" modified="2025-10-08" version="1">MRLSSALALAVPLLAAAARKPSSAILLSDVSSITLHAGRKTTGRRLMPIPQLRCVSSQSLCRIHPISVMRCTNEGASYSSEDIEWACTASLPDTLQLASTDVICEGYDSADDPYVLRGSCGVEYRVELTPAGRQAYPELARSNFTNTLASVLFMALFVGVFFWIIWSACMSPAGFGNHGGYRRRWGGGGWGWGGPGFGGGPGFGGGPGWGGKEADQGTWTPGFWSGLAAGAAAGYMGRGNREREAAYYTHRAARFGGGGGGGMGGARAETRESTGYGSTRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV63</accession>
    <name>A0ABR3YV63_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aldehyde dehydrogenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_004849</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000147">
        <property type="protein sequence ID" value="KAL1891776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07105">
        <property type="entry name" value="ALDH_SaliADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050740">
        <property type="entry name" value="Aldehyde_DH_Superfamily"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353:SF6">
        <property type="entry name" value="CYTOPLASMIC ALDEHYDE DEHYDROGENASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="4">
        <location>
            <begin position="18"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1891776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="475" mass="49735" checksum="C9D7C9A8B3FBECA2" modified="2025-10-08" version="1">MEHTVPLVINGVETVAASTFPVISPITSQHAHQCSSASVSDALSAVASAEKALAAWKRTTARERRDILLKAAAIMESRSEEITAYMKAEIGAAASWAQLNLNIATDITKDVAGRVATIQGSIPGTQSADVGGLVLKEPLGVVLAIAPWNAPVILGTRAVVFPIAAGNTVVFKGSETSPRTHWAIVSCLLEAGLPAGVLNFITATPANASAVTSSIISHPSVKKINFTGSSAIGRIIGRIAGENLKPVLLELGGKAPAIVWNDADLDVAAAQCALGAFANAGQICMCTERILVHTDVRAAFETKLAACVKQFFPTAEEAPILATASGVTKNRALVADAVAKGARVLVGNADTEESSATRMRPVVLADVTTDMEIYHIESFGPSVSLIGVDSEEEAMRIANDTEYGLSSAVFTSDLRRGLRFARGIEAGAVHINHMSVHDESVLPHGGCKGSGFGRFNASYGLDEWVRTKTVTYNIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVD5</accession>
    <name>A0ABR3YVD5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein prenyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_004614</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein prenyltransferase subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000134">
        <property type="protein sequence ID" value="KAL1892291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.120">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002088">
        <property type="entry name" value="Prenyl_trans_a"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129:SF3">
        <property type="entry name" value="PROTEIN PRENYLTRANSFERASE ALPHA SUBUNIT REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01239">
        <property type="entry name" value="PPTA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48439">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1892291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="382" mass="43730" checksum="1018CC71010DEEC9" modified="2025-10-08" version="1">MSRTLDPNAIAALKTGNHQKVFDEIADVFTYTHNPQIAARTCLIEIEILSGFGFDPSNNVLRDQNAVAVPKLRLVQAFFVARGILQQLREPSPAGSNKASSEQIHRATAVCLLMDAENLTAANMRKRLITRQLASVPTAASTSDATSAHNIAPTIVSLLRREKWLLDSLLTSRLHRHTKSPTLWNHRRWLLKLLRLHGLEGDVDTAQDLLDVVCVSGERHARNYYAWSHARWVVRNFQYVTEKLVEIAKSWAWKHYTDISGWSFLLFVLELHKKLAPPVYRDTLRLTESLQWRNESVWWFLRTVSAGRLLSDDRETLEQAREAFVCLGTRLFEDGVEHMGDKREEGKRYEDSMKGAGCDGAREVWERAKTWVEKYRDLPNMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVK8</accession>
    <name>A0ABR3YVK8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Probable vacuolar protein sorting-associated protein 16 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">vps16</name>
        <name evidence="5" type="ORF">Cpir12675_004744</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the VPS16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000141">
        <property type="protein sequence ID" value="KAL1892019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.780">
        <property type="entry name" value="Vps16, C-terminal region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016534">
        <property type="entry name" value="VPS16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006925">
        <property type="entry name" value="Vps16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038132">
        <property type="entry name" value="Vps16_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006926">
        <property type="entry name" value="Vps16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12811">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING VPS16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12811:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04840">
        <property type="entry name" value="Vps16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04841">
        <property type="entry name" value="Vps16_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007949">
        <property type="entry name" value="VPS16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vps16 N-terminal" evidence="4">
        <location>
            <begin position="7"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="Vps16 C-terminal" evidence="3">
        <location>
            <begin position="505"/>
            <end position="799"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR007949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1892019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="819" mass="91561" checksum="A2293E27F76E5E08" modified="2025-10-08" version="1">MDASQPRTNWERLGDKWYRKIQLYTEVFDQDLNLDNYVIAAASYGGSLALWKDDTKLIAYQAGKSSKHSIDVYSYAGKPLRQIPWDNGTIKGLGWSEDELLLVVMPEGTVRCYDYQGEFTQFTLGHGAENYGVVSCKFYGQGLVALLGNNTLISVASYSEPRPKPLAPVPNGTVHAWAIVPPNHTLSRCVEALVSLENTIYYVDAMDCEDRFLDIGPFSHISVSPNGRRAALYTVGGIAHVVSSDFQERFVEHNANSEIPPKHVEWAGSDAVIAWEDEVHIIGPDDTSVTYLYDTNRVHVISEHDGAIVLTNDVCEFIQEVPPETNQVFGQFAESTPASILLDAVAQLELQSPKADDYIQLIRGSLTEAVNTCVNAAGCEFDIHWQKQLLKAASFGKSVLDLYNSDDFVDMCETLRVLNAVRFFEVGMPLSIEQFHRLTAERLVERLLCRNEYLLALKVAQYLRIPTDGIYVHWATAKVKVGKEDDETVCRLIVEKLQGRPGVLFEEIARAAYSEGRGRLATQLLNHEPRGGRQVPLLLAMEEDELALDKAIESGDTDLMLFVLLQLKAKLPLATFFRLLNTRPTASALIETLAIREGDNSLLKDLYYQDDRRMDGAIVFLRESLDQPTSRIAADKIALAAKILAESKESNFELHSLKESTMLLRTQEALGRDLTDEFTGLSVNETMFQLIKLGNFGKAKKLQSEFKIPEKVAWWIRLRALVAKRDWAEITEISKQRKSPIGWEAGNPRVAAMFIPKCTALGPGITISMYEKCGLKVKAAEEAVRLRDADAYVRILQAAGRGTEEGREIERLGATVFKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVQ3</accession>
    <name>A0ABR3YVQ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit L</fullName>
            <shortName evidence="4">eIF3l</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_004774</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000143">
        <property type="protein sequence ID" value="KAL1891915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03011">
        <property type="entry name" value="eIF3l"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019382">
        <property type="entry name" value="eIF3l"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13242">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13242:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10255">
        <property type="entry name" value="Paf67"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="5">
        <location>
            <begin position="247"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="467" mass="53933" checksum="AAB990141FE0ACFA" modified="2025-10-08" version="1">MATYPPSNVMLDGDSEIEEDALVEQIHHQDDDEEQEIDDGLQPDDIQARVLAAAQPLDVSAPLDVKFQSYDSYCSLFHFILNSDGPVDVEAPSYYWAWDAIDEFIYQFNSFSSYRMRIARQGNNEEEIQILRANPNTWGCYSVLNVLYSLVQRSQMTEQLAAQRRGEDPLTVAGEYGSRNLYQRLGYFSIIGLLRVHCLLGDFSLALKTLDDIELNKKAMFSRVMAAHYTTYYYVGFSYMMMHRYADAIRMFSHILVFFQRTSRMQKGSQQDSIAKKNDQMYALIALCVSFHPTRLDDSIHTPIREKYGDQLLKLQRGGPESLPIFEELFRASCPKFVSPVVPDFDNPAANIDPIEHHLAVFMDEVKTNMWNPTVRSYLRLYTTMDLPKLAGFLEVKPDELRSWLLVNKQRTKQQRWNESLHGLLEGETVNVSDIDYAIQGELIHISEAKVGRKLVDWYLRNLSRTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWI5</accession>
    <name>A0ABR3YWI5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UDENN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004865</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000148">
        <property type="protein sequence ID" value="KAL1891679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052809">
        <property type="entry name" value="Actin_polarity_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012860">
        <property type="entry name" value="Afi1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037516">
        <property type="entry name" value="Tripartite_DENN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28245">
        <property type="entry name" value="ARF3-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28245:SF1">
        <property type="entry name" value="ARF3-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07792">
        <property type="entry name" value="Afi1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08616">
        <property type="entry name" value="SPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50211">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDENN" evidence="2">
        <location>
            <begin position="186"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="893"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="913" mass="101812" checksum="91D49BD124A33F44" modified="2025-10-08" version="1">MAAPPPLPPPAVPRPGISRAETDLGTVHAHAHTHAPVGPFLSASGSGSSFSAAPQRTSLSSFPPARSESQLSLAQLVTRATGRSPNINSSSGASMNSGQFSSHAHSNSQNHNSNHSHSHSQSHAYNNSMSHSQSLGYGLDGPDGSKSISQHSSLDTPSRRNISEGPHPLRRLRSQYPRGSIENHVEYILVASFDIDRGPVMEHQYPVAITGDEHMLAELMLPDQAHMRHQDWTIFFLHKDISQEEEEAEKLAKAARKRRRQRRRDREAGILSTDDEDDGADEDDDYDDFDDDYDDLDDDDDDQSDAEPEGGEGPPLIYVLNLVNTKQDKTVRRGAVVKAMSICTRHPFLHIYKPLLLLALEEYFKSPVPETLSMLYDAVNAMDLSLMPRLTVLERHLLQVSDNKELFVEKFDQMIQMRMAEDRRQLAQQAANGEDEGDEGSNASAGTGAPRNGPKSIPQAYSVPRDTHEFESRVMYKGIPIPIKVPVAMMPESVGDFSIIKLIQNFSASYAKSPTAYTPHPHLTTSGPNTHPIIVLVNALLTQKRVIFLGHNMPSGDVAEAVLAACALASGGVLRGFTRHAFPYTDLTKIDDLLNVPGFIAGVTNPTFEMHPEWWDVLCDLPSGKIKISSKIEGGATMEGSVYFQQQHPNYAQLVNHYQTAASAVNDYTGDVAFMNDILKAINSRAGERVVRAKWRDWIGKFTRIAATFEETVYGASALYIGGDEGEQPTLPGLAGHGYVWPDEVSKNKELAGNVTRIEGWRNTRSYYSFIQDLAQLYNVRPLKNIDLYHMQDRLRTQRLTPSQSKDLYLAFCKTIFTYDEICLLLSAAPESHAGLFYLALGLFHKDREVRFHVADLLERISEHDAGRHWWVALGRFEKVAFQRTKRDQKAEMRARIEKEKEGRSPEFDRRIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWN6</accession>
    <name>A0ABR3YWN6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_004562</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000132">
        <property type="protein sequence ID" value="KAL1892409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012879">
        <property type="entry name" value="CCDC47"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12883">
        <property type="entry name" value="ADIPOCYTE-SPECIFIC PROTEIN 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12883:SF0">
        <property type="entry name" value="PAT COMPLEX SUBUNIT CCDC47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07946">
        <property type="entry name" value="CCDC47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046855639" evidence="6">
        <location>
            <begin position="21"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="377"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="377"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1892409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="431" mass="48733" checksum="A2151420E83D69AA" modified="2025-10-08" version="1">MTKFLDIVVACMALIASAAAEATDTASDAPKPTSSSFVQKMFVFLGSSGQISTIGRPYTKWYNIHERFTLADFQGEAYIILAATILFSIHFSGVSKNRTKANAWARANGGLLKQEYAMVGFGGSPTVDSDPNDASGTFREKSLFEFQSYATGRRNVAFTDVNLVLNRRFNPLVMLIEAGISFMWDTITPPADQCELITYPFDGLELKTIRQVALTAEPKTAEKSTYDGFVWGIVNKDQMKRLRNDRYDLSLTFTKDSPKLPIWATVMSESAEITAALLTKDLVAAIESAGDLFDYLVVTDQPGQKPTTLEETRSRKRIFCRYRLPGDNNYEPLQPLMEQFLRLPDHLVSVCHFRPEVLRKVKTVRESAISQIKKEMETEKAEERAAERERLKKSKREEALTHLDAKAQKKYLDKEREKEIRKMQKKSTVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX32</accession>
    <name>A0ABR3YX32_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Condensin complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">cnd1</name>
        <name evidence="14" type="ORF">Cpir12675_004589</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the CND1 (condensin subunit 1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000133">
        <property type="protein sequence ID" value="KAL1892303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026971">
        <property type="entry name" value="CND1/NCAPD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032682">
        <property type="entry name" value="Cnd1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007673">
        <property type="entry name" value="Condensin_cplx_su1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024324">
        <property type="entry name" value="Condensin_cplx_su1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14222">
        <property type="entry name" value="CONDENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14222:SF2">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12717">
        <property type="entry name" value="Cnd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12922">
        <property type="entry name" value="Cnd1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017127">
        <property type="entry name" value="Condensin_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 10" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="6 10" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensin complex subunit 1 N-terminal" evidence="13">
        <location>
            <begin position="87"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Condensin complex subunit 1 C-terminal" evidence="12">
        <location>
            <begin position="1011"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="148"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="469"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="896"/>
            <end position="919"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR017127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF12922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1892303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1196" mass="133944" checksum="EC7ED021818D2732" modified="2025-10-08" version="1">MESANFDINDALKHYMSDPFSVPTNEADGQLLDCENDPDSITDGHVAAILDQIVDAVADSPESLARALYFDSLQFILKYSSSITANTLGRIFDVVMSGLSVQADAIHADIEIQEEQETMQHYKMMLEMYGFLLQWTITAVETKAAEKPSGAPVRLGRGKGKKTTASKEKDGSWNSETQLQTALDILGKVLKLKLSKIFLTTPERDTFIGLMTRPVSTVLESEQRVKNTTIKMHAFKVLCIAVKHHGHAYAAQISIVQNLTYFEHLPEPMAEFLHILAETYDYPQLAEEVLRELSNKEFNSNDTRGPKSVSTFIVRLSELAPRIVIKQVTILAKQLDSESYTLRCALIEVCGNMIAYLSRLEERGENYKTQLNAFFDVLEERFLDINPYCRCRAIQVYVRLCALEQKFPKRRQRVAELACRSLEDKSSHVRRNAIKLMGTLIKTHPFTVMHGARLSRKEWQERLDKANEELDSLQPPSDMPEMEGNSQLLDGDAPSDHGPKGFNEMTDEQKIAAVKKAQTAAATSGAIEKLSLTKRYYTEALKFIDVLHESTETVCQLLGSRNKSEVIEAMDYFEIGDAYDIEQNKVGIRRMLRLIWTKGNSDEGKGVQTHLIECYRRLFFEAPDSFSPNDAANYVARNMISLTFGATPAELTSLEQLLSTMMKGGLIPEAVITKLWQVYGVQKREISRAHRRGSIIVLGMMATATPEIAVGEMETMLRTGLGSYGRTDMLLAKYTCIALRHINPTGRSKEGPGGKPITFSRLINDHAVLSRLTSIIEIATDSKEWYGVAEQAINAIYALAKHPDTLCSSIIRRKTRAVFGNPSSRPTSSNDTQTQIMDVDTTQTQNQSQGRPSSQFKSRDVAVGLSQLLFIVGHVAIKQIVHLELCEQDFKRRKQEREKQSAEKAATAAPGKDKDTPADELDLIGGTTEDDFTEAMAHIRERELLYGPQSLLALFGPIVSEICAASTKYTDKGLQEAATLCLAKLMCVSSEYCEANLPLLITIMERSSNATVRSNAVIALGDMAVCFNHLIDENTDFLYRRLADDDASVKRTCLMTLTFLILAGQVKVKGQLGEMAKCLEDEDRRIADLARMFFTELSTKDNAVYNHFVDMFSLLSAEPNLAEESFRRIIRFLLGFVEKDKHSKQLSEKLAARLARCETERQWNDVAFALGLLQHKNEEITKLVSEGFRIVQTVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX57</accession>
    <name>A0ABR3YX57_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRIAP1/MDM35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000120">
        <property type="protein sequence ID" value="KAL1892921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007918">
        <property type="entry name" value="MDM35_apoptosis"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05254">
        <property type="entry name" value="UPF0203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="179" mass="20335" checksum="36B387D84D25EC57" modified="2025-10-08" version="1">MSASLAPECNEIKDLPSNTVLEYLRGERSENTQCLALFNQYRSCLTVALKERGIDKLLEDAREDNKENDSTYLNRKSASDALLSGIYHQGSRYSVSVEAVPFMYSLIDHKQTKGRAFLLCLVTSLVIGHPTWSVPNGIDLEQWQKRIAGIESPDEHSFQLHEFRAYEAVERARRRLSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXI3</accession>
    <name>A0ABR3YXI3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004728</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000140">
        <property type="protein sequence ID" value="KAL1892039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046656201" evidence="2">
        <location>
            <begin position="19"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="171"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="289" mass="29560" checksum="3BBC91BE9E071DEB" modified="2025-10-08" version="1">MKLSTIFSVFSAASLTAATSIIAYTGTAPSGPSPTTFSSSRGGYSYSVSTDDPNVRMYPTCIMIRAIYYCTESEVDSDELYLIAIGQLQDFELDSDTISGPVTTAASNAPAPTVIVGYQPVQVAQHDSCIFFNGWVCNEDPVHGSEDADEVAAVRQASANLFAANAELVSSGDSSVPDVTSTDTDESDDEDIEVDPKPTVLPRDEEASNSGRLCGRCSKCKCAKNGAAAATGAYGTGVAHPTGTGIAYPTGTGAINPSGSGVGATDVPTSGAKQLAVPLAGLMIAALAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXW0</accession>
    <name>A0ABR3YXW0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytoplasmic dynein 1 intermediate chain 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_004207</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000114">
        <property type="protein sequence ID" value="KAL1893229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050687">
        <property type="entry name" value="Dynein_IC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442:SF22">
        <property type="entry name" value="CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442">
        <property type="entry name" value="DYNEIN INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="525"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="198"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1893229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="709" mass="77328" checksum="F713292E480CE2D5" modified="2025-10-08" version="1">MQQRRDEIMQKKAKLAELKRQRELRATQASSSRQSIGSSDLGSPSGSNRADSRRDIDSLINSLVGDGRAGPHSAPGGSTPMSLTLRGSRPNSVLSAGDLSTEASDFATLTSIATTVPVLTTAPLTTVYEMEPQHAHDTAKEVVTYSKAVQTTEEWCGPILTGVGTGPANGRSRGHSMAFSDVDDYSSMMMSPSKQRLSRREREREEELRQNIRREIEQELKAAQQLLDDGQMSSADGPASTNFPARALSAEELEAVMGSEDFLDFVEHSSKVIERALDQEYDILMDYALQGQDVDEEDDGSGNTGGKGRHKIKEIAQFYDERWSKKRMVSGIDWSPKFSELFLASYTKNPTAPNDPDGLVQVWNMHLHDRPEFVFHAQSDVLTAKFSPFHPNLIVGGSYSGQVLLWDTRAKAAPVQKTPLTGHGHTHPVYSVDIVGTQNANNIISCSTDGVVCAWSMDVFAQPQELLELKLPSPAKLDEVAPACLAFPQADPTFFLVGTEESAIYPCHRYDRAGAKAGIEAGVSYRGHHAPVMSIDFHPARGPVDLGDLVLSSSLDWSVKLWRVRAPAATSTSAAATDGHMTPLVDFVREDVVYDARWSPLKPGVFGLVDGAGWLELWDITVETEEPVARISPSSRKDGRSMLSKSLNKLAWEKTESKRVATGGIDGTVTVFEVGNGLGGKEELRAEEWTSVKKLVNRIETMGVNGVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY25</accession>
    <name>A0ABR3YY25_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_004191</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000113">
        <property type="protein sequence ID" value="KAL1893258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185:SF1">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="5">
        <location>
            <begin position="16"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="4">
        <location>
            <begin position="20"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1893258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="294" mass="31900" checksum="938E020BF9DFDCE2" modified="2025-10-08" version="1">MDSSMTLANGPPKKVLSIDGGGIRGLSNLLILEKIMEGIQQEENLPGVPKPCDRFDLMGGTGTGGMNVDESIKAYKKLSETGFCQERTISKRAVLAVTKNDVVTLPTIFTTYPPLTTILSQCSVWEIARATSAAIAFFKPIKLGRDDIEFVDEVFGNNNPCETLIKEAEKLFPLNRIIALSLGTGLGGVVQINDLQISITSAFEKMASSSKATHHRLKDRYGGTKDYHRLDVISGLIDVTLLDSSALSKIAGLTESYLNENGELVTDCVKALATNGITRPLLRINVVIELILTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYB4</accession>
    <name>A0ABR3YYB4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF1279 superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">NAT2</name>
        <name evidence="4" type="ORF">Cpir12675_004163</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000112">
        <property type="protein sequence ID" value="KAL1893380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045866">
        <property type="entry name" value="FAM210A/B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009688">
        <property type="entry name" value="FAM210A/B-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21377">
        <property type="entry name" value="PROTEIN FAM210B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21377:SF0">
        <property type="entry name" value="PROTEIN FAM210B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06916">
        <property type="entry name" value="FAM210A-B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1279" evidence="3">
        <location>
            <begin position="109"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="255" mass="28154" checksum="9D714BA20A1CDAE7" modified="2025-10-08" version="1">MYRTGLKLQTGSASRWPSIQGLATRLLPNRAFSNLHPQLRLATSNPNFPLMRSRSILRLNIRAGAKQSLHSVFRARFNSSSTSGKMREAAEKVKQKASEGKEQAQTLGQRLKILSKQYGWVALGVYLGLSMLDFPFCFLLVRVAGPERIGHLENVVVSAVSSVIPDSVKPFYHECKAKLKQRRTNEAEREGSEDGSNDGEVESKGASLGTQLALAYAIHKSLIFIRVPLTAAVTPKVVKILHRWGYKVGNKPSKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYJ9</accession>
    <name>A0ABR3YYJ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000108">
        <property type="protein sequence ID" value="KAL1893466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="432"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="521" mass="57242" checksum="E0EDF30783B9783D" modified="2025-10-08" version="1">MSTYKQFLAAPNSSLLAPDASLHYITTTTTISGAGNIIKHLNTVSKQIKKKAESVLDEVNGRSASVVQLETTLEFVTSGGPYTPGLDDNFLADHTVSLPITHFVHYDAQGRITQIRQNWDQGALLKDLDIIGKSGRNWPISSYTDQLRLINNCIKNSGKAAPSYASEEPAPHQQRGRDNSALSLFRAREEIESEAMPAVASPYAGGRPQQRSLHQIVGTESDSDNELDRSNSPSRRRLAKAGASRSVAANRVFSEEELPPSPPRAETGRPQIHVKPDPSKYNHFDFDDFSTPQKVVPSRGSLSRDARHWENDPSDLPETPVAHGKAQPKPRRETEKHFDIEDDGPAIPRRNPRPRGAISNETQGLYENHVYREDGSAPTPGPRQVCGADMAHRQKDFQTNYKMTDIPGENTPQAKHAVPSDRKKVYENMEANWESTDVSPAPKGKESIRIAGDGMGSRKNLGSQTNDSGGIHISGDGMGGPKGTNRDWLFGGGGDEEPEEAKPKPKPRMANRNQPSEQWGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ59</accession>
    <name>A0ABR3YZ59_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA excision repair protein ERCC-6-like 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_004182</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000113">
        <property type="protein sequence ID" value="KAL1893249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029256">
        <property type="entry name" value="Heliccase-ass-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057931">
        <property type="entry name" value="RHH_ERCC6L2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050496">
        <property type="entry name" value="SNF2_RAD54_helicase_repair"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629:SF7">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629">
        <property type="entry name" value="SNF2/RAD54 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25806">
        <property type="entry name" value="RHH_ERCC6L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14773">
        <property type="entry name" value="VIGSSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="203"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="583"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="821"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="967"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="830"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="967"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1023"/>
            <end position="1033"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1893249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1052" mass="117101" checksum="979F460DE8AD5D12" modified="2025-10-08" version="1">MEESTGSESENLNDLTIGSLKKSNLRKRPLSPSIPDRVEWTDDDGDDIPVQIGSSAARAKNAAKGRKKCQPRRRGRPLKAHRQDGGRQATLAGEVLHSSGSKTAADDEEANDAKVNEVPDYVRARRALFDADTSASLRVPPDSVALVADITPHMTRPVFSASSGVRPSREFAGVDLQDSGGTVPAPVAQYLRDYQLEGVRFLHRLFVWQIGGILGDDMGLGKTVQVAAFLATAFGKSGDERDQHRMRRMRAACRSEAEGGVLLWYPRVLIICPASLIHNWRDELNRWGWWHVDVFHGSPTQKADVLQTARNGRLEIMITTYDTYSNNRSSVNLVDWDAVIADECHRIKDQSSNTTRAMAEVNALCRIGLTGTGIQNNYDELWTLLNWTNPGRFGSRSQWQTAITRPLVVGQSHDATLAEILGGRRTARRLVENVLPPFFLRRLKTLLADQLPRKRDRIVFCPLTPLQERVYEGFLRSDVVKCIVNAHQLCTCGSDKRQGNCCHRKAPDGRLRVSCIFPSMMTLQKLANHLALLLPKSSDSCEKQSAGMAAFRECLPDTWEQIYKAREAMQTLANPEFCGKWKILKELLRMWYADGDKVLVFSHSVRLLNILNHLLTNTSYTVSYMDGSVSYDERARTVAAFNTDPHQFVFLISTRAGGVGLNITSANRVVIFDPHWNPALDLQAQDRAYRIGQTRDVDVYRLISAGTVEEIVYARQIYKQQQANIGYSASAEPRYFKGVQHDDDRKGEIFGLQNIFSYRKGQLVLKDIVHNTNVAEAKVQLNLMDIDVQQVAADAEKTFKLEDPAEDVAISQVADIFRGHAKAKNSRTAKQPDADGTAEPKADPIHALLRAAGVAYTHENSSIIGPSHIEDTLARAPTNPSTSGAPPWAPLNDVVERRAARTRTGLQRAHFVYNPPEDVQVRQFCQMARDLGFADATAFALVVENGSVEQRRAFLTEFYQKRREKLFGGDSGRGVEDQEKKGGEEQQDQKEDSDNEERENQEGNDTADEDAASQAPGLDGTDESASSNTCTQSPDRKLPSCSDPVFVSEDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZS3</accession>
    <name>A0ABR3YZS3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pseudouridine synthase deg1</fullName>
            <ecNumber evidence="6">5.4.99.45</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">DEG1</name>
        <name evidence="6" type="ORF">Cpir12675_003891</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.45" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000100">
        <property type="protein sequence ID" value="KAL1893873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160154">
        <property type="term" value="F:tRNA pseudouridine(38/39) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02569">
        <property type="entry name" value="PseudoU_synth_ScPus3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00171">
        <property type="entry name" value="TruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041707">
        <property type="entry name" value="Pus3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142:SF5">
        <property type="entry name" value="TRNA PSEUDOURIDINE(38_39) SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pseudouridine synthase I TruA alpha/beta" evidence="5">
        <location>
            <begin position="275"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="35"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="166"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1893873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="555" mass="62846" checksum="02389085A4B663A0" modified="2025-10-08" version="1">MDAKAPRSDSPYAKWTRESLLAHIKSLEEELQKNQLALPPLPSLARPEGLAKKKKNKAGEDGEDGQKPAKKAKVVKNIDPSKYNSRYIALKFAYQGKRYGGFEYQESQELPTIEDELWKALTRTRLIYPKDDNVVDFDCCEYSKCGRTDRGVSAFGQVITLRVRSNRPLPKPEGSAGGLTEAMEVDSTEKAPEKEWDPIRDEIRYCSVLNRVLPPDIRILAWNPDPPADFVARFSCRERQYRYFFTQPAYAPIPAPVQNSQSSNGWLDIDRMRNAAKHFEGSHDFRNFCKADPSKLRTNYTRTMFEVDVVEVPEASTDLAAYMQSEVLKPEAGPVKSEGLEMNPRGTKVYYFSVKGSAFLWHQIRCMVYVLFLVGQGLEEPSVILDLLDVEKTPARPAYPMADDVPLVLWDCIFPVEGDAERRDAVPWVWADADDQSALGFSRNGNIEALWSEWRGKKMDEMLAAQLLLMVSKQGQTPKILESKERAVAVLGDKTLPPRIFEGGNAGFFGSKKYISLEKLKKGIPVDEANDAYARKNGYKDAQEMRLKRGYREAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZZ4</accession>
    <name>A0ABR3YZZ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004061</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000107">
        <property type="protein sequence ID" value="KAL1893630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="232" mass="25794" checksum="4838FA5D92FCC194" modified="2025-10-08" version="1">MKQQHRPPPLALSNSPASTTARPPVDSNEAEAVRTAGPDSRYLSKCTGLSCFLGIVAETAHTVVCMFMMLMLAFYLNYDEAAVNRSSGPPAITLIILLSIDMILNFYSIAHFDKPLTGWVAFIKCILIFGYIVIFLVYLASDGPFPKSYSFWGIKADYTSVIVYSLIWIISVWDLAIIVVNRKTLLYWFVDVVDVISQRQQTLETASIDDKQFEAAGSTRLVSMSPFVGRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0F4</accession>
    <name>A0ABR3Z0F4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Centractin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ARP1</name>
        <name evidence="2" type="ORF">Cpir12675_003799</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000096">
        <property type="protein sequence ID" value="KAL1894111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10216">
        <property type="entry name" value="ASKHA_NBD_Arp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="380" mass="42443" checksum="1CC42E53558D1EFE" modified="2025-10-08" version="1">MTDSLHNAPIVLDNGSGTIRAGFAGDDLPKCYFPSFVGRPKHLRVLAGALEGEVFIGQKAATDYRGLLKIRYPLEHGIVTDWDDMEKIWEYVYGEGLKTLSEEHPVLLTEPPLNPRSNRDTAAQILFETFNVPALYTSIQAVLSLYASGRTTGIVLDSGDGVSHAVPVYEGFAMPSSIRRIDVAGRDVTEHLQTLLRKTGYVFHTSAEKEVVRLIKESLSYIAADPKREEKEWLSAKTDVIKSAEYVLPDGSKLKVGPERFRAPEILFDPEIIGLEYPGVHQIVVDAINRTDLDLRKSLYSNIVLSGGSTLTRGFGDRLLSEVQRLAVRDMRIKIFAPPERKYSTWIGGSILAGLSTFRKMWVSIDDWHENPDIIHTKFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0T8</accession>
    <name>A0ABR3Z0T8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">G-protein coupled receptors family 2 profile 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_004054</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000107">
        <property type="protein sequence ID" value="KAL1893623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053247">
        <property type="entry name" value="GPCR_GPR1/git3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42058:SF1">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42058">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="7">
        <location>
            <begin position="59"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="431"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="537"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="583" mass="63066" checksum="F0A18C51E5EE5F9E" modified="2025-10-08" version="1">MSSDLDLLRGGCQAPFFDQASFSDDDGFIPGRICIPSNAANSTCCLPCPLVDWVYPDSFHTMASVADWISVFGFICCVFLLISWAALPVEKTHRHYLSICLTIAVAIMSLGFVVPLAADPEQCINEITPNDMSTSSVCAISGTMIMLGGFAGATWVFLRALSLHLQICWQVVVGRNFMLIAQAIGWLIPTLIVAVALKYSGVSFRFGQTCHVNHNNSMADFWIPMLVFSGFTLVLQGATFVYCINVYLASLNDSSSTTENSTNLPTHSVIGSSNISPRQAYRRVKRVVQLQWRGITIVLIILMDVIFFSVVFVYQDRTIEAVRKHPEKATAWVSCLLRNSGDKGQCIDEASGLAVQLSTIVTVLILLAINGIWLLLFLGNWGMLMGWADLANGLLGRKPEPIEFVSKDATLQSKSYELLSRETNSVTATSMIGSPNLMRPAPTASHPVNFSPGPYSDMDSKSPISPLPDSLISDGARSSTIRASAGFASYPPINTAGDYSNEDVGVTAVQSVAGSPVEDGQRTPDYFGSTTRYYAPHRSFSSPHAPRAGSVSLSPPLPAQNGVARLGQQNDGHAINPLGMNRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z107</accession>
    <name>A0ABR3Z107_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003737</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000093">
        <property type="protein sequence ID" value="KAL1894309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="447"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="458"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="491"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="527"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="556"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="636"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="656"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="705" mass="75487" checksum="B01BD936E7B7C3FD" modified="2025-10-08" version="1">MSMTRIIADSDDEEDQLTSEALSTRSGPPPAKPAAHMFTHVASQGPTPGLNTHGIQDTPVVVSGVSTLNHDATRLASARSNSTDPAFFAALYSREHRAALGQGSSLPSVLGPPTTATVAVNSGSQQPHIHCISDLTVLPQGLNSLVKRAATLNNLSSSLQSCFVPKQQRLNSTADGPDAQKSQNLSTSTSSKPTILSKIEKPRSVSELEASKPLTKKRKLDRWRDSSPDIILVTEAQALTSGYSTSACTTKSPAKHGDIDLHAFDSSPTPPVSAKKQRRIAPRTEEVDELAQPYVGPPQNLTPLGPSIQRPPLEQNNDASKWQPAPAPMAVMEVSRSTQAALTLNAKIEPDGVRVEPSIIAEQLEGMKQQLEEPPRSGRSVHDQIADSEDEYESDPPLVRLAPETGKGKVLKEKEAEIPDTQSFSQHTSPSLVLGEGMVYKVAEKIQAEQSVSEKKEKSTKKKALSRKQKATSKRLLGKKHGVATAVATEEPQRQMRKLTDVIAISDDESNDDDHSSTPTSASVSARKPELEPEVKPEPKLQLNSEPPPESPAKTAKGKTKKSITKKPLVKKTNLKKGTAKSKKPATPDPLPVVEIPSPKPETSGPVAPRGNIEISPPNPAPQESAESAPVRGRSESTISTPTTKSTDSAPKPNDRQSTPMGGKSNTEASQAKPVISLSVSKPVYRVGLSRRSRIAPLLKIVRKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1Z7</accession>
    <name>A0ABR3Z1Z7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">3-methyladenine DNA glycosylase</fullName>
            <ecNumber evidence="5">3.2.2.21</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MAG1</name>
        <name evidence="5" type="ORF">Cpir12675_003545</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.21" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000086">
        <property type="protein sequence ID" value="KAL1894654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003905">
        <property type="term" value="F:alkylbase DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051912">
        <property type="entry name" value="Alkylbase_DNA_Glycosylase/TA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43003">
        <property type="entry name" value="DNA-3-METHYLADENINE GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43003:SF5">
        <property type="entry name" value="DNA-3-METHYLADENINE GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="2" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="4">
        <location>
            <begin position="191"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="52"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="221"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="230"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1894654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="411" mass="44864" checksum="2BA2170CBA65939C" modified="2025-10-08" version="1">MTTRRSARLASLLVDPVSKPACPISARSTNSRGILAVTKKRKSDVSEAIPITRVSTEAPSSPPSFGEPDELPELPTPVTPRKKTKTHTLLITPSTRYLAASNLTSGTLLSPETCCIVAPSSPSTVSRDFKIDRLSVKISNKDTLLSDALRHLVSVDARMAPLIDKHHCTIFSPEGLSQTVDPWEGLVSSIISQQVSGAAAKSIKQRFVNLFQSTQDAKIRLEKEKGEKGTTANTSTKNESPQAPFPAPSQVVKLDLGSLRSAGLSQRKAEYIHGLAGKFVSGELSVSFFAQASYDDLVERLIAVRGLGLWSVEMFACFVLRRPDVFSPGDLGVQRGMAAFEGRDVARLKSSGKGKWKYMSEKEMRDISQRFAPYRSIFMWYMWQVENTDIEAMQGDAKPTGKEKKAVNGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1Z8</accession>
    <name>A0ABR3Z1Z8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003842</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000098">
        <property type="protein sequence ID" value="KAL1894058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040410">
        <property type="entry name" value="UPF0658_Golgi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34391">
        <property type="entry name" value="UPF0658 GOLGI APPARATUS MEMBRANE PROTEIN C1952.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34391:SF1">
        <property type="entry name" value="UPF0658 GOLGI APPARATUS MEMBRANE PROTEIN C1952.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="340"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="407" mass="46196" checksum="3376C64AD08F3E58" modified="2025-10-08" version="1">MAAPYNDRNYNMQAFNDVPAHHGEATSKGIPSSRSNGMTTHFADTWWPRFFFGVVSVQAVVCLVIESYVFYKFQDSIDDGPDSNAAAVVQRKTIPTFLALFIFGFLYEMVLVWDALRLKNTIQVIGLCFANMAMMVYTAIQVDQIHDALRVISGVLDSTQKSIYGNDSQAPDSMFPNVLKDELPASHYWADISGYLIAMPCFCAVTTLCMIFAAWKLYQEFAWDILKYIGADYRMKKRFLHYQVYIALLKFDFFFFLGFMIQFLVVVTNHGDPEFGLTIAIIPVTVAILLGASFATRREIKSLMIITMMLYFVALAYFVFKLVRIYQPTYRKDYYPVKKSLTAFAVITIALLLVTIANGYMCMRSFGKGLKAHLQSAKADAEKAENNNNSIHMVDIKPMPLSRMTID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2D1</accession>
    <name>A0ABR3Z2D1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Retrograde regulation protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RTG2</name>
        <name evidence="3" type="ORF">Cpir12675_003516</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000085">
        <property type="protein sequence ID" value="KAL1894775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.150">
        <property type="entry name" value="Exopolyphosphatase. Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050273">
        <property type="entry name" value="GppA/Ppx_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003695">
        <property type="entry name" value="Ppx_GppA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057512">
        <property type="entry name" value="RTG2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30005">
        <property type="entry name" value="EXOPOLYPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30005:SF0">
        <property type="entry name" value="RETROGRADE REGULATION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02541">
        <property type="entry name" value="Ppx-GppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23566">
        <property type="entry name" value="RTG2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ppx/GppA phosphatase N-terminal" evidence="1">
        <location>
            <begin position="52"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="RTG2 C-terminal" evidence="2">
        <location>
            <begin position="386"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="588" mass="64389" checksum="CC30AC8A5E9F784D" modified="2025-10-08" version="1">MALELVTLDNFRDKLPGWDPLNHDRQLFAIVDMGSNGIRFSITDLSPPKTRLLETVYKERASISLYDDLNSSKKSPPTFSKSTIKEVSDVVHRFQKIAEDLYSVPTANFTIMATEAMRKAGNASAMIRGIGTTVFVLEPQVEALFGAAMGSRSAFHKIDKGGLFFDLGGGSVQMSWINTAKPNYEITAAQTGKSLPFGAARLRNILESKDVDMRTTEIKALQSGMSLALAELCNQFPDLQEARDGEGVDILMCGGGFRGYGSMLLHTDEVSPYPIANVANYSVSGSRFRDTQSLLDLNANYKGKIFGVSKRRRKQFSAINTVVEALIAAVGNIRMVTFCAGSNRQGSLMMKLPPQIRESDPSESLMYLNPRFYECQADEEYSFFVKAVSESLRSALPSGAGFDPTNTIFGLGLQNYLVSHLWDNLGNDEAGNAALALHHATSQFPDIPGLSHIGRAALAITLVARWDNQLGPADKLVLDNLKKVLNRADPNGAFWHVYLGAVARIIAMVAPKRPTEAKDIAYLSGAMLFKAEFKDALQIADGFNLQIKIKDSESLGLDYDDLRDIISATREEKNAQGFKAIETTFTSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2Q3</accession>
    <name>A0ABR3Z2Q3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Choline transporter-like protein ctl1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_003473</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CTL (choline transporter-like) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000083">
        <property type="protein sequence ID" value="KAL1894828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007603">
        <property type="entry name" value="Choline_transptr-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385:SF88">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE PROTEIN CTL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04515">
        <property type="entry name" value="Choline_transpo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="341"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="384"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="413"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="447"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="487"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="531"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="704"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="744"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="50"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="167"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="130"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="232"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1894828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="812" mass="89671" checksum="2196F375C3A8FE85" modified="2025-10-08" version="1">MYVIDEPVCTYQNTKTKIETPYIHNMTNNLSYLYASKFLAQSQAKASTFVGQENAEAGPSSRPGADVGQQPSRPSMNSRAFLSPYRTTAAPYQQTGGNIASSRFGPLAFGSRLAQQQEAPLFHSHYNDFREEDDDDDDDDDDRGRDAADLYALQRSRRVAAASKLAESMGSEAETSNISLDHSRGGYSSFADENNESSELAPAFQSSFPKGLRSSWHGNRRNTLPKQTKQHGAIDEESEHRTSDTEAPSSKGGMATVGLDSELIHDDDPPASLMGEGDDLLDSSPAPFQVFNDAHGREPHNHAAFRQQPIFGESEIDESRIQDVVVLSSPTEPELFSHDSFFAWLYLIMLASMVSTYFLVWLHTSTPDSSHPIGDTIYTTLESSMYMLGVDTVVAIMVALIWLAALQSFVRPMVIIIMVGMPMMSVSFFLYPFISSFHGRGGAQERAMRWASAVPLAAAAAWVYCVYKGRHSIRQAIEILEFSSRILHINSALVSVGLTSLVAIVVWTWLWLTMFARIFLDGHMSTTKSQWIMEGSTWWLGAWFIFMYMWTVSVINEVHRATSAATVSQWYFHRNAIPMTPSQEVVKAAINHAFTTIFGTISLATLLARMIRMPILFLPARMSFVIQRIANMIMPTSVVALTNPLTVTYAGIHSQNLTTSARGLSSMEFLGPQTPTATLTPRVFNTPTDDPRHSGLVPYRLAKMLLYASRFVMAVAMGFAGWVVTSRQLAIEKPDGSGVIRGSLYAYTVGLVASFIGYSVMGSMESVLGNIMDAVVVCYGSERRMQNGVGAYCMEAAYLLGGRRRADDEAYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2W5</accession>
    <name>A0ABR3Z2W5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003463</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000082">
        <property type="protein sequence ID" value="KAL1894969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="673" mass="76618" checksum="A26DC7F2E644BE09" modified="2025-10-08" version="1">MMKTKLASNQKRPGSGSTAGRDSCKDTKCKSIRPQNINLPLEWEQKNLGHLSRGAVFELAKNYARSNDIEPARCAFTKAATLCPCSRGLIRPPCKCKDFRRAAGKTPPEIFNEAMHNCKCIVSKRFQKCDDAIHISSLNYLAALSLVGDDFRRAASEASWLLEISPRKLEGYLRLAQVAIKQKEAHFAWQIYTAAINMAQANNLEQDPNYAKLVKMREPLNLKFSKLDPIKILPYELLLNIVEQLSIRDWQKPIIIDAAYLDLLRKYSSSLKDLCIDVGQFKSDWFTSGLESAFNFDHLILSVKYPQSLTDFEALMVIAKNVKAFNVSLYDYDETPQRPLTFPLFHELQDLTLKFHLQHRMCLNMLARNAPQLRRLWINEMGLQCEPVTPESVQMNPREYFSQLECLIIDKVAMDNINPFDFFKYSFPRLKIFRFRNVSCRNETTTTNANSLSHFCTLSPVPNHSFVQTRDIGVLSIDLLRRPQNPATRCLEASLHSGIVECVSVEMSLWRGRNLGMSAYKKTALWGSKGVRTLVLAFPPRELVQSRDSLQFWDEGLIPFLESFPNLNSVIIHESSPFAREPRNKAAIVEAIVGLSSSVRTVYDVEAKGSARTFLHELAARNGKRIISYQDFDSLEHPLNFYSDPKRQLPDGSRDPALSFPISTMPGQPCVFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3B7</accession>
    <name>A0ABR3Z3B7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="20">Acetyl-coenzyme-A carboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">ACC1</name>
        <name evidence="20" type="ORF">Cpir12675_003363</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>N(6)-biotinyl-L-lysyl-[protein] + hydrogencarbonate + ATP = N(6)-carboxybiotinyl-L-lysyl-[protein] + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13501"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.14"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>hydrogencarbonate + acetyl-CoA + ATP = malonyl-CoA + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11308"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.4.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000078">
        <property type="protein sequence ID" value="KAL1895134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06850">
        <property type="entry name" value="biotinyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.460.10">
        <property type="entry name" value="Biotin dependent carboxylase carboxyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1770.10">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049076">
        <property type="entry name" value="ACCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049074">
        <property type="entry name" value="ACCA_BT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013537">
        <property type="entry name" value="AcCoA_COase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45728:SF3">
        <property type="entry name" value="ACETYL-COA CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45728">
        <property type="entry name" value="ACETYL-COA CARBOXYLASE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08326">
        <property type="entry name" value="ACC_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21385">
        <property type="entry name" value="ACCA_BT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0092">Biotin</keyword>
    <keyword evidence="9" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="17">
        <location>
            <begin position="50"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="16">
        <location>
            <begin position="207"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="15">
        <location>
            <begin position="685"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="18">
        <location>
            <begin position="1506"/>
            <end position="1844"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="19">
        <location>
            <begin position="1848"/>
            <end position="2169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAL1895134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="2275" mass="254467" checksum="F0D22D4C0F355A83" modified="2025-10-08" version="1">MTEIQDSQTLAVRSKTKRSVGDHFIGGNCLENAPASKVKDFVAQNEGHTVITNVLIANNGIAAVKEIRSVRKWAYETFGDERAIQFTVMATPEDLQANADYIRMADHYVEVPGGTNNHNYANVELIVDIAERMNVHAVWAGWGHASENPKLPESLAASPKKIVFIGPPGSAMRSLGDKISSTIVAQHAKVPCIPWSGTGVEEVVIDKEGLVTVSDKVYGKGCVNSWQEGLERAKAIGFPVMIKASEGGGGKGIRKVESEDGFDALYKAAASEIPGSPIFIMKLAGNARHLEVQLLADQYGNNISLFGRDCSVQRRHQKIIEEAPVTIAKPDTFRAMEKAAVRLGRLVGYVSAGTVEYLYSHADDKFYFLELNPRLQVEHPTTEMVSGVNLPAAQLQIAMGLPLHRIRDIRLLYGVDPRTATEIDFEFKDPESEKTQRRPRPKGHTTACRITSEDPGAGFKPSNGVMHELNFRSSSNVWGYFSVGSQGGIHSFSDSQFGHIFAYGENRSASRKHMVIALKELSIRGDFRTTVEYLIKLLETEAFEDNTITTGWLDELISKKLTAERPDPMLAVVCGAVTKAHITSEACFNEYRTSLEKGQVQSKDLLKTVFGVEFIYEGFRYKFTVTRAGLDSYHLFINGSKCTVGVRALSDGGLLILLDGKSHNVYWKEEVGATRLSVDSKTCLLEQENDPTQLRTPSPGKLIKYTIENGSHIKAGQTFAEVEVMKMYMPLVAQEDGVVQLIKQPGATLEAGDILGILALDDPSRVKQAQPFVSKLPVYGPPVITGSKPAQRFALLYGICQSILMGYDNSIIMQSSLKDLISVLRDPELPYSEWNAQFSALHARIPNKLDAQLAQIIERSHGRQSEFPSKQLSRAINKFLDESISPSDVDQMNTTLLPLTGILEAYAEGPKVRELNLMKDILEQFWDMERLFIGQKQQEESVVLKLRDENKDDIAKVVQIVLSHSRVNSKSSLILAILDEYRPNKPSTGNISKYLRESLRKLTELQSSRATAKVSLKARETMIQCSLPSIEERTAQMEHILRSAVVQSTYGETGWDHREPNFDVIKEVVDSKYTVFDVLAMFFAHDDSWVTQAALEVYIRRAYRAYKLHDIQYHLDDVDKSPLFISWEFSLRKLGQTEFGMPLPSAIPSTPATPLSGEFDFKRVNSISDMTYKLASGEEEPRRKGAIIPCRFIEDAEDLISKALHTLPSFNRSSSVNLVKDLSDKRRPPTTGKPGELSAVVNIAIRDSEGQGDADLLARIVPIVDQYRKEFLAHGVRRITFMCGHSDGSYPGYYTFRGPKYLEDDSIRHSEPALAFQLELGRLSKFHIKPVFTENKNIHVYEAIGKTVETDKRYFTRAVIRPGRLRDEIPTAEYLISEANRTINDIFDALEIIGNNNSDLNQVFINFTPVFNLQPEEVEHSLQGFLDRFGLRGWRLRVSQAEIRIICTNPDGTPLPMRLVITNTSGYIVDVDIYAERKSEKGEWVFYSLGGTKDKGPLHLMPVSTPYVTKNPLQPKRYKAHLMGTQYVYDFPELFRQSIQNSWTKTVKKNPAIASQQPKTGDCMTFSELVLDDHDNLDEVNREPGTNTCGMIGWIFKARTPEYPTGRRFIVVANDITYKIGSFGPKEDGFFNKCTELARKLGIPRIYLSANSGARLGLANELMPHFKVDFKDPENQEAGFNYLYLDDEAKKRFERDVITEEISENGEKRHKIITIVGAEDGLGVECLRGSGLIAGATSRAYNDIFTITLVTCRSVGIGAYLVRLGQRSVQIEGQPIILTGAGALNNLLGREVYTSNLQLGGTQIMYRNGVSHMTANDEFEGVSKIIEWLSFVPKERNAPVPVSPSSDPWDRDVIYTPPQKQPYDVRWMIAGRHEDPDSPDSTFEAGLFDKDSFVEALGGWARTVVIGRARLGGIPVGVIGVETRTVENITPADAANSDSIEQVANEAGGVWYPNSAFKTAQAIKDFNNGEQLPLMIIANWRGFSGGQRDMYNEVLKYGSYIVDALVDYKQPVFVYIPPFGELRGGSWVVVDPTINPTYMEMYADKNARGGVLEPEGMIGIKFRKDKQLEAMARLDPTYADLKKQVDSGVETDKDKLQELKSQMAAREKQLLPVYSQIAIQFADLHDRAERMKAKGVITAAIEWINSRRFFYWRLRRRLNEEHILRRMMPSPLSSTTNGIVLDEKNRGIRERNLELLASWSSIADFKGDDRAVAEWYEANHKSVADKVEHLKNESLAQDLAALVQANKSVGLKGLRDVLRTMPIEEREAALSFLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3G3</accession>
    <name>A0ABR3Z3G3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rab-GAP TBC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003359</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000077">
        <property type="protein sequence ID" value="KAL1895176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.750">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF9">
        <property type="entry name" value="GTPASE ACTIVATING PROTEIN AND CENTROSOME-ASSOCIATED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23436">
        <property type="entry name" value="RabGap-TBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="3">
        <location>
            <begin position="485"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="37"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="216"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="256"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="388"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="518"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="852"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="82"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="229"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="259"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="270"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="339"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="398"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="527"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="548"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="559"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1895176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="994" mass="109361" checksum="E9431D3DF87B0A63" modified="2025-10-08" version="1">MIEVAKMAEALEARSIYAPSDMDSETDNFEDALSLRSLTHKNPSTSNMRITQTLFKTEEEEEDEDSSTSGGLEDNAGHDNEAGDDEDDDEEEEKTDKGTLTSAHTSPISSPGTSKRSSTASSIDSKDKLQFAMGQPDLALAIPMPVPTAVVNVTSPVGNRPTTPMVPIFDHSLNNGANLDNVSLDDDAGPTVPTKDAHGTNATAAITVTNTLAGSKEAAAVPQPPPKDPSTASKSHGSKSLSLSTLTSAFPSLPWSPAASDNSGKSLNQNSNASPNASPKTTKTTSTTKTTSSSTTITPTPPARRLTSPFSWLSRNSSRERDSAPLMSSAKDTRGRRNTGGSVATLNSNNDTMLDRLDEENDSDDEVRNPHRASLKDRFKALRLKEESGALDGEDPSGQGTLSPISATTATDDSETPVDRSIHTPLVSNPNPSLAPGTVSGISAGPSDMSSSEVDWDLWQNVVYEGPAAVARSSAEELNVAIAKGIPHAIRGVIWQVLAQSKNEDLELKYRELVNRGTEKDNKDRSSSGTALSSASSSLPLVVEKTDSSASSVRSSSSTTKDVATPSTAVTEKNEELSVKALAAAAAEKTRKQKEDAVTLQKLEKVIRRDMGARTSYSKYAAAQGLQEGLFGVCKAYALFDEDVSYAQGMNFIIMPLLFNMPEDEAFCLLVRLMNHYQLRDLFIQDMPGLHMRLYQFERLLEDFEPALYCHLHRRGISPHLYATQWFLTLFAYRFPLQLVLRIYDLILSEGLSAILRFGLVLMQKNTSALLAMNDMQQLTTFLRDKLFDVYIDKDPSAGGILENGFFGSSSSSLDKEVYRADQLVRDACDIKMTPELLKTYTTEWEEQTKAKKERENELENLRTSNASLTIRLRKMEERLEACDGEQTAMANELVHTKVENEELRDENEGLRGQVRELRIVIEHQPEEIEKTWTLERDDLMKRNLNVHEENQKLEAELATLEEELVQTKLKYAEINSQHETLNRKWTDLKRQFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4K0</accession>
    <name>A0ABR3Z4K0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Dynactin subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Cpir12675_003376</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="13">Subunit of dynactin, a multiprotein complex part of a tripartite complex with dynein and a adapter, such as BICDL1, BICD2 or HOOK3. The dynactin complex is built around ACTR1A/ACTB filament and consists of an actin-related filament composed of a shoulder domain, a pointed end and a barbed end. Its length is defined by its flexible shoulder domain. The soulder is composed of 2 DCTN1 subunits, 4 DCTN2 and 2 DCTN3. The 4 DCNT2 (via N-terminus) bind the ACTR1A filament and act as molecular rulers to determine the length. The pointed end is important for binding dynein-dynactin cargo adapters. Consists of 4 subunits: ACTR10, DCNT4, DCTN5 and DCTN6. The barbed end is composed of a CAPZA1:CAPZB heterodimers, which binds ACTR1A/ACTB filament and dynactin and stabilizes dynactin. Interacts with ATP7B, but not ATP7A, in a copper-dependent manner. Interacts with ANK2; this interaction is required for localization at costameres. Interacts with N4BP2L1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Stress fiber</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Myofibril</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the dynactin subunit 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000078">
        <property type="protein sequence ID" value="KAL1895147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008603">
        <property type="entry name" value="DCTN4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13034">
        <property type="entry name" value="DYNACTIN P62 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13034:SF2">
        <property type="entry name" value="DYNACTIN SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05502">
        <property type="entry name" value="Dynactin_p62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0007">Acetylation</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0832">Ubl conjugation</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00093507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1895147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="574" mass="63127" checksum="CE45197BF6E33C89" modified="2025-10-08" version="1">MASLGPYTFIQCPCSDPSTILRSDDNNTTSPTDPENDIDDDDDMAFDPRAPRANYSLFPLEYLMYCADCHEIRCPRCVGEEIIIYYCPSCIFEVPSSNIKSEGNRCTRSCFQCPVCVGTLVVTSLDRPSDRSTVAAPAQSAPPPTPTSGGPYALNCTYCLWSSSEIGIEFDKSNGVYGQLSRVRNGGAPKLSAREFKEKHKDRSADGSGLQTTIDPDIHFSNLKAFYQNQSSDMSSSSGSGIGAIGDLGFGSPGSLSRIMSLYTGGSMGGKRTQPKNTVLSEASSITEGLKPTQLDESAALAKLRASRWEDTVSMEQNENQLHHCRFTDELRPVPVLLRTKRSKRCPVCRHIIAKPEAKVLNTRYRIRLVASSFVPSISIKPMNSGPPPPSRNIPVAPTLPTLQPHAPTQFILTFQNPIFETIKITLATASTTPGRFPSKITLLCPQFTVDANTDMWDDALKNEGDKRRTRGPDEMNQAEAGKIWDRGRNWVSIVLEVVPAPLDLQAAKPAKGDDQDLHDPLLREDEDILEIPLFVRVEWEVEAQESPSKDKMAKEKKELAYWCVLGVGRIGTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5S3</accession>
    <name>A0ABR3Z5S3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">thymidylate synthase</fullName>
            <ecNumber evidence="2">2.1.1.45</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TMP1</name>
        <name evidence="8" type="ORF">Cpir12675_003196</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; dTTP biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.45" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000071">
        <property type="protein sequence ID" value="KAL1895557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004799">
        <property type="term" value="F:thymidylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00351">
        <property type="entry name" value="TS_Pyrimidine_HMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.572.10">
        <property type="entry name" value="Thymidylate synthase/dCMP hydroxymethylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00008">
        <property type="entry name" value="Thymidy_synth_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045097">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023451">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036926">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000398">
        <property type="entry name" value="Thymidylate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020940">
        <property type="entry name" value="Thymidylate_synthase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03284">
        <property type="entry name" value="thym_sym"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11548:SF2">
        <property type="entry name" value="THYMIDYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11548">
        <property type="entry name" value="THYMIDYLATE SYNTHASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00303">
        <property type="entry name" value="Thymidylat_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00108">
        <property type="entry name" value="THYMDSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55831">
        <property type="entry name" value="Thymidylate synthase/dCMP hydroxymethylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00091">
        <property type="entry name" value="THYMIDYLATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate synthase/dCMP hydroxymethylase" evidence="7">
        <location>
            <begin position="16"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="314" mass="35511" checksum="A093596E54CDFC1F" modified="2025-10-08" version="1">MTETTCQQPRNDEELQYLDLIREILETGEHRPDRTGTGTKSIFAPRPIKFNLTRDGQDVLPLLTTKRVFTRAIIAELLWFIEGSTSSIPLSEAGVKIWDGNGSREFLDNAGLVHREVGDLGPVYGFQWRHFGAEYVDAKTDYTGQGVDQLAEVIHKLKTNPYDRRIIMTAWNPADLKKMALPPCHMFAQFYVSYPGAKEDEEKPKGHLHCQLYQRSCDMGLGVPFNIASYSLLTHMIARTTDLVPGSLTHVMGDSHVYLDHISALEVQLERQPREFPTLKISKESGCSIDGWKVEDFVIEGYNPHKAISMKMSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5U9</accession>
    <name>A0ABR3Z5U9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002978</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000064">
        <property type="protein sequence ID" value="KAL1896001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045439139" evidence="1">
        <location>
            <begin position="20"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="194" mass="21547" checksum="1DD36DCF1C8A8B8A" modified="2025-10-08" version="1">MRSFSLFASLLLPVLGVQAGVLEDHEYRVSYSPDNAYTPVSLMTARWTGNIVNKIAINKNDAVATIYIARNSEEPNSEKKLNLSQIFSAVCGLRDTSPGQINQVAFDSLDSNTQAVISDYRTANGKTDEDSFTVTPSDDSWGKFTNLDYYTDAKSLVPSKDISEIKVTAFTASDVWDWAERNGHYDLLQFTYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z615</accession>
    <name>A0ABR3Z615_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2415 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003023</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000065">
        <property type="protein sequence ID" value="KAL1895983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019417">
        <property type="entry name" value="DUF2415"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43991:SF9">
        <property type="entry name" value="DUF2415 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43991">
        <property type="entry name" value="WD REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_8G05640)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10313">
        <property type="entry name" value="DUF2415"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2415" evidence="2">
        <location>
            <begin position="279"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="482"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="572"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="482"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="577"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="596"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="690" mass="76262" checksum="05CA8825B0F9C14C" modified="2025-10-08" version="1">MPILDCEDDAYYPTDQIILTGQRKRFNIGIHSQCLTAAQGWVCCGGEHGEFSAAKLGTIETLKSGNFEIPNSFFASHDSPIAVAKSARFVRERVNCVTIWFPQDQQPQQTFKIIPHHGAYNEPVAVLSNNDKTVTLVSLNSFSDGEEPQSLCSLTYPDFVNRAVISPDCQFLAAVLDDPYLYIHHRTENEEWSSGSDEKDQFHWKLCAKILLKSQFESDKTDRRGSFALAFSPSGQYLAVGTQHGVVSVFRTDRLAKDSDNALVKTFNSSRAGDRHGNGAIRDMAFCPGKYGLLAWTEDRGRVGIADIKSNFSKRQIIKLGESSSFGLNAVLDPNVYLAPTSTANVRNAALLARELHALASELPSSTSDEATQIPVFNRVVNPPPAPAPASRNLSFDPRLLENLRHAREREQGRSMGYQEGNSAPRRAYARSTDSTDNTNNSLSALVTPSTSSRSMLQSALLVSSLRLSHRHAANSINTANTLLSDSNSTNRGSNNTIDDPDNSSSDFAWDSEWDENPYPVPSARHVELRSNIRSFLDDWRQAPLLPGGSQITGEARSNIQLPNQAHVEVEGETQEPLLTSGNTRPMVTQRDRQSSNESSLHSSFWANNEPSNPVTTPTNRRMMGSGPIYREYMARRNNSLNALTSGRDNTSGMAWSTEGDTLYVGSEDGIYEMHVNTSYWKIISSIQLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6S9</accession>
    <name>A0ABR3Z6S9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003007</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000065">
        <property type="protein sequence ID" value="KAL1895967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="351"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="408"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="433" mass="44822" checksum="3288BD13911B805E" modified="2025-10-08" version="1">MSYYDNGSQWSGAPGPQGPSPSATGAANAPPNSSGNNSNSNSNNNSANNGSAASASNWDHQASQARAPRWKSGTETTDVSLTKPSGGVAGPTAADEFAFSYQFDEVDRAHENLAKSGKIFAMGPRREFSAANPISGFGPSIRPRPDGRLPPMPGVRPNSINDGPDRALQTSFQNFYSPQRHQSPRGPNETEQALQTKRKMAAQRERELRNLHTEQQFQRNTMSDSPFNNKPRTDEEARELIARQRSALYGEGAFAEKTAYVDETGAVHSGAPSIVGPSVAGSTGPASLRGASPMTPFDPRNIPSSVVIPADSISVTDSSIAPIATPTSAEMPLNSLSPQPGATSKALFDNPPRSGSVSSPIGSSPARGDSGSAIKPLSVAPIGTRPSGTSANVTATTKPATTPISSPGGWGRGGGSAVWGQSSGLGAQASVWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6W2</accession>
    <name>A0ABR3Z6W2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">G3BP-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_003197</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000071">
        <property type="protein sequence ID" value="KAL1895558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00780">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002075">
        <property type="entry name" value="NTF2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039539">
        <property type="entry name" value="Ras_GTPase_bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10693:SF20">
        <property type="entry name" value="AT27578P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10693">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02136">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="NTF2" evidence="5">
        <location>
            <begin position="40"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="392"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="183"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="228"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="351"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="479"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="17"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="240"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="277"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="351"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="479"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="501"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1895558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="523" mass="55744" checksum="B5B708C400CF6350" modified="2025-10-08" version="1">MSTNGMSSGHNQHKASDSYNTTEQQSSNASPTQEPTKDEVGWFFVQQYYTTLSKSPEKLHLFYTKDSQFVYGEEAQVSNVSVGRSAIEERIRQLGFQDCKVRVNNVDSLSSFDNIVIQVIGETSNKQEPPRRFVQTFVLAKQTSGYFVLNDIWRFIIDDEEEELVPEQTATDTIAPDVEEKAFETTEPEMDEEKALESQAEVASEPIVEPVAEPIAEPTVVEEIAQNSEAVAEPEEDVEEKPSQPEAPQKDEAKAPESKPEESKPVAIPATEETPAPVKPPAPTKVPEPVARPVPVVPMTWAGRAAAAAAAAAAAAASPKAAAAGPKAAAPPAKTPASSVAANKASAASQAAATPTAADASSSSEWQTAGSDSKRQNRPQSMIGGSHEKETVNAYVKSVSDKINEADLKNTFSVFGQVVYCDINRAKNCAFVDFANMESYKAAFTANPHIINGETIMVEARKPKTGAYGNYPGSNFNGRGGMGRGRGNFGDRGGYVPRGNFGRGRGGGGGGAPRGRGPQISNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z704</accession>
    <name>A0ABR3Z704_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000058">
        <property type="protein sequence ID" value="KAL1896453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1896453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="70" mass="7879" checksum="7A6D94E04488ED1D" modified="2025-10-08" version="1">MPLIKQSWLPQQHEMTVNAMNDQQTTDAAPSGARLSADSKLQELWDEAEEKDTDLVEIKRASYDTTIADT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7F8</accession>
    <name>A0ABR3Z7F8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional repressor general negative regulator of transcription subunit 4</fullName>
            <ecNumber evidence="6">2.3.2.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">NOT4</name>
        <name evidence="6" type="ORF">Cpir12675_002938</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000063">
        <property type="protein sequence ID" value="KAL1896025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16618">
        <property type="entry name" value="mRING-HC-C4C4_CNOT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12438">
        <property type="entry name" value="RRM_CNOT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034261">
        <property type="entry name" value="CNOT4_RRM"/>
    </dbReference>
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        <property type="entry name" value="Mot2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039515">
        <property type="entry name" value="NOT4_mRING-HC-C4C4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
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        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
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    <dbReference type="InterPro" id="IPR013083">
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    <dbReference type="PANTHER" id="PTHR12603">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12603:SF0">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 4"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF00076">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14570">
        <property type="entry name" value="zf-RING_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="15"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="121"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="235"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="341"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="503"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="586"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="636"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="785"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="93"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="239"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="255"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="276"/>
            <end position="289"/>
        </location>
    </feature>
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            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
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            <begin position="605"/>
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        </location>
    </feature>
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        <location>
            <begin position="636"/>
            <end position="647"/>
        </location>
    </feature>
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        <location>
            <begin position="787"/>
            <end position="798"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1896025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="873" mass="93913" checksum="70867C8C9F037A1A" modified="2025-10-08" version="1">MAPQDSFIEEEEDTCPLCIEEFDLSDRSFHPCPCGYQVCQFCFNNIRNNMNGLCPACRRPYDDKTIKYKLVTQEEEALFKANITKSQKRRVHEQRQRESQKREAEKESRKSLVGVRVVQKNLVYVTGLTPTVREDELLKTLRKPEFFGQYGAIQKISISNRKTSDGQNQSLGIYVTFEKPEEANRCINAVNGSHNGDRVLKAQLGTTKYCSAWLRYEPCTNRVCMFLHEKGDEEDSYTRQDLSSMNSLHTQRPFSNTTTGSSSSGAASRSTPVVRTLQSLSASQPMARTSSKDDPEQNSSTDGSALPLTANWARNQQRSPIGNHATASSPAILASLPVTCEGSTESSGKIASIDDSPTPAGAAAANASDKGKGKGVAHPTSAPASSSSASSSSVSSSQNASAQTTLPPPASPKLKEETRTEPAVQAPTQPQSEEAIARMRILKDLDSSWTFKKLSADDFAQLEMHPPMFDFQGGEKRRCMREAEETRNTIVQEPAAPEIQETMEAEQLESSGSHALGGEPEDREPLRDGYGQRQASASQPIRNDAPFGSAIGSSFAAQSSTPVGVVGGRSLTPQQQLFLRSQSALGEQGTPGLANSGSMFPLPSHTRQSSRLNFGADSNSSQLASNPRLLAQRSLAQQTSFQHQNSPYYPASVSGPPPGLKSTATPPNMFQGPGFGNSSFTAPRETNDVLLQTILRDRTNNQAQAQAQAQAQAQAQAGKREYLTSLFSNQYPPTSLSLTPTSTLSLSSIAAPASAAASGLLASLYGNQQQQQQIGASAAFQDFGPKQQKKKGKKHRHANTSSSGGSGLVDLADPSILQARMQQQQQQNQNQSNAGVGVGVGSVGVGQGIFGGVQSQGGYNPNMVYNAGYGTRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7K2</accession>
    <name>A0ABR3Z7K2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CN hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002737</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000056">
        <property type="protein sequence ID" value="KAL1896641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039703">
        <property type="entry name" value="Nta1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11750">
        <property type="entry name" value="PROTEIN N-TERMINAL AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11750:SF26">
        <property type="entry name" value="PROTEIN N-TERMINAL AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
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        <location>
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        <location>
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        </location>
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        </location>
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        <location>
            <begin position="1001"/>
            <end position="1108"/>
        </location>
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        <location>
            <begin position="596"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="813"/>
            <end position="826"/>
        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="828"/>
            <end position="840"/>
        </location>
    </feature>
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        <location>
            <begin position="858"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="922"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1004"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1043"/>
            <end position="1055"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1108" mass="119804" checksum="31BABE6900CAE9F9" modified="2025-10-08" version="1">MRIACLQFSPVRGDVNNNLSRADSVLLKAADNDKLDLIVLPEMAFTGCKFQSRQAIQPLIEPSLSGISSLWARTTALRHDCYVAVGYPEKTDANDVLEGGPRFYNSLMMVSHDGESVVNYRKPHLYTTDEAWAMEGNGFYGGWIAGMGRVAMGISMDLNPYRFEASWESFEFAHHVLATDADLVIISMAWITGEDVHSWSQTPREPDMDCLSYWIARLEPLIRAETAHEILVVIANRTGIEDDVVYAGTSAVLGFQGGEVKLYGLLGRGEKGLLVVDTDELPMGKLVYRPDETTVERQPGESDLPGLVPNPDAAYTMSPVGSPDGSLSISPLCAASNSATTPDSVDGRQTTHVAERDALKLGVVPEQDEPAGGRDFGVVTEWAALTDSRIESGAASEGSPKTRARVKMGSDSKSVQAGSVPDVSMSSKIARTKSPALHRCTDSLNNRTGGPPSIASLLQTPNKLSFSGTQNQHTRHQSLDAVIERSLLAKPRVGSTLATRQKAPAPAPTMHPSARSPSTANPKADQPKLKLQTNSAVLRQMEDTNTSHLAHATLCAKSYKPPVPLDDGLRNYPATAVEENHVFDWQPLEPKPAGASLSQDNQGVESCASSPPNSLSKKQRANRPKLSITTTSPSALPWKKTDTRGIVSAVDPPRSLWPVAGNGKNQTNRLYEPASAIAAVSKDQFWATASVPQTGNTEAFNLASISYTLGEVAMAGTTPEAEKALAEEDADEAWYRSPIDTATQANPFAADVPRGREDASAHFSSVEESIGRQYKAPNSHARDAGAIYPPVPTPSQSSFCQSNALRFLTTPEESFRQRSRNEKPRDATSVTHSGQTTTGSLRRAMTEVDVAYPPIPSPSIYSSQNQKPQRQQQKWPVGNPSRPYEALRSAEALAEPVSWVDRWMPPPAGVYQQGEQEDPNSQQLQHAGQGQQQQQQHYHQGPHEYQHQNQPIVKPGLNLLVPAFSSSTETLATPSMLNPKTPKTPAGHLVSRLNARRHPASITAKETGNAYVSRSEASQNLHIPRPHREVSAEAEPINGNANDSDESESTDEDLGNDVGGDRKPAGAEDDGPCTPKAMSLMMDIEHERPHENSTTGPIILGGSHTILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7R5</accession>
    <name>A0ABR3Z7R5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mannosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MNN4_1</name>
        <name evidence="7" type="ORF">Cpir12675_002656</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000054">
        <property type="protein sequence ID" value="KAL1896708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009644">
        <property type="entry name" value="FKTN/MNN4/W02B3.4-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007074">
        <property type="entry name" value="LicD/FKTN/FKRP_NTP_transf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15407">
        <property type="entry name" value="FUKUTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15407:SF32">
        <property type="entry name" value="PROTEIN (MNN4), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G03790)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04991">
        <property type="entry name" value="LicD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046932981" evidence="5">
        <location>
            <begin position="19"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="LicD/FKTN/FKRP nucleotidyltransferase" evidence="6">
        <location>
            <begin position="87"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="272" mass="31098" checksum="1648EB5650DC691E" modified="2025-10-08" version="1">MKPTSILTSSLLAVSVSAAAITNTIPSRQDSQQPFSSISAEHEYFKQASFNPQYDPRFASEPLPYVQQKAAMQVLIQTCLSTLADLGIEAWLMHNTLLGWWWGQHNLPWTSEADLQIAAHSLSFLAAYYNMTMFFFKYPDVPEGRHFRLEINPHFASTTVSPANHVDARWIDLQTGLYIDLAAIRYERPRAPGAAPTLRDKRGFHYADTDIFPLWETTYEGVNAMIPHNFKRLLVDEFGVSALTDMRTNSHFFQEDTMTWEHARSEKEFSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8N2</accession>
    <name>A0ABR3Z8N2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Synaptobrevin homolog YKT6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Cpir12675_002576</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endomembrane system</location>
            <topology evidence="8">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the synaptobrevin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000052">
        <property type="protein sequence ID" value="KAL1896928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14824">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.50">
        <property type="entry name" value="Longin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010908">
        <property type="entry name" value="Longin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001388">
        <property type="entry name" value="Synaptobrevin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051097">
        <property type="entry name" value="Synaptobrevin-like_transport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21136">
        <property type="entry name" value="SNARE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21136:SF168">
        <property type="entry name" value="VESICLE-ASSOCIATED MEMBRANE PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13774">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00957">
        <property type="entry name" value="Synaptobrevin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00219">
        <property type="entry name" value="SYNAPTOBREVN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01270">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50859">
        <property type="entry name" value="LONGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Longin" evidence="11">
        <location>
            <begin position="11"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="12">
        <location>
            <begin position="150"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1896928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="235" mass="25690" checksum="6B151F942075C165" modified="2025-10-08" version="1">MSSSSSNATPLLYACVAHQTSIIAEETTSAASAASSLASLVLPKIDHATSQKVTYTHGSNHIHYISETPSEHATHPSAGGLTFLVVAESTLGRRIPFAFLLEIRNRFFAKFPEASFNFGDLPNYGAASFNPDLKSLMIDFGTSQNGHDGALNTVKQGIEDVRGIMTRNIEGLMEREERMDQLVDRTDRLGGNAQEFRVRSRGLKRGMWWKNVKLMVTIGAVVALIILLIILSLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z950</accession>
    <name>A0ABR3Z950_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000063">
        <property type="protein sequence ID" value="KAL1896044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="338" mass="39388" checksum="10168E66ED1169C2" modified="2025-10-08" version="1">MTNPYVFGDEEEDDDSRQHDHGHNRNQAPEQIGESKGHHGGQDHEDDEREHEVEGLFVAFPFTTQVYQPEPYRGSDPEWQEYIKFSKDGELQKELRDNLLKIVIKKLGADDKRSKLYMKPPRRSRMWLDYQYPSAPAPEYWYSGILYANDGIYWTNAKADSKLFIDLDRIMYPQLVASFIYQFASQSVVRHYDKLRAIWYPDTPRPQRPVIQMNPVHQILPSQDKGFKLVLEEEDPSNSTIVEKITRLALGHAIAVTEPMKSTWKQFGLALQRKWSEYKYPPPRGSIMLTGMLEVETPKVWVLVDVTAFWEPKEKEFHGPSMMMSVKGTLLKVQAPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9E8</accession>
    <name>A0ABR3Z9E8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphodiesterase</fullName>
            <ecNumber evidence="3">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PDE2</name>
        <name evidence="6" type="ORF">Cpir12675_002470</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="3">Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cyclic nucleotide phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000048">
        <property type="protein sequence ID" value="KAL1897213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023174">
        <property type="entry name" value="PDEase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00126">
        <property type="entry name" value="PDEASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDEase" evidence="5">
        <location>
            <begin position="258"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="664"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="741"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="761"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="808"/>
            <end position="833"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU363067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1897213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="874" mass="97327" checksum="E4164FBFA2902906" modified="2025-10-08" version="1">MDSKLSHVIFIHKDVQHERLVPARFRETSSDNANTAPECRHITESLQALLEYTDGASCISTLIQLLDSSLAKLTPFIVMIDTPYDEEIPQPQRTRSGSPEKPSRELELHTPDDEVYGLKLLQRIMTEAHLRSMSKLVVAIPVISYPIGPMSPSTSALHEFPSQPINTSEWVDKRLLQRCLDLGATDVIVGSINQKCVTSLEVHAYRAYRDALRDQQAILEMRRGRRRSWVGVNEEKPYSYLREAMVSGLMKGICRYGGEDDLMAQTKIAVPLSRQSVIADAIGKWHFSAHSFSDDELLFASMLIFKHALTMPELEKWKIPTDQLINYLVACRAAYNNFVPYHNFRHVVDVLQATFSFLVNLGALPTYPFSYGNEKELPVKSPMAELLEPFEALTLLITAIGHDVGHPGVNNGFLVTLNSPLAQLYNDRSVLESFHCAAYSQILRRYWYSAFEDTKMRSLMISSILATDMGLHFDYMKKLADVTAKLKENDSIADWDAKTLLEQKSLACSLIIKCADICNVAREYPTAVEWMHVLSDEFARQWTMENELQIKSSLMSPPKQDMASLCKSQTSFMNLFAIPLFQGVAAVMPNMQYTVDQLVTNKAVFENFGREMSTGDQAALLELRSTEVSMKNVSDLDGVPNNDNDQMTLVSGKDDQTICKSLSETDEQERKARMLVPSLGSMPVSPYTLQGPRGRSASQASSQDGNEDIITSFESVADFAASDPFNIHQLSECIEVGLVNPGKQRRSETTTEDSTSGPSTNDWASQTNSATGKLPLSPSTRGTSINSQSSHDEALDVPVRIVFPDDSSAATPTNMDSYSRSPDDSGASNTSSIGRAEGETLKKKPSRFRMNAFTFFKRKGTSPAPVSRVSRHMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA34</accession>
    <name>A0ABR3ZA34_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Importin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_002522</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the importin beta family. Importin beta-1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000050">
        <property type="protein sequence ID" value="KAL1896997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058584">
        <property type="entry name" value="IMB1_TNPO1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25574">
        <property type="entry name" value="TPR_IMB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="11">
        <location>
            <begin position="33"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="9">
        <location>
            <begin position="801"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="385"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="385"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1896997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="946" mass="104868" checksum="379BA1EE0A268D98" modified="2025-10-08" version="1">MSSWEPNPESLGQLAQYLKNSLSGFNKELQSQAEKMLKNAMTSPDFNNYLAYIFSSPETPPGANLSTEEFFTVRSAAAIMIKNNIRTSHATIPESSLSLIKMSVQMGLQDKNTLIRNYAGNIATEYVRRMGLFSWPELIPMLLGIALNEGGTTQFSNEAQEGAMSALSKICEDNTKALEREHGGERPVNVLLPKLIQATKSPLTKVRVGALIAINEFVPRKTQAMLNCIDELLSQLFALSSDQGVDVRRQVCHAFVLLIDARPDKLHPHISGLVEYIISQQQSDDEELACEAAEFWLAIGEHDHLWQALAPYIDKIIPVLLECMVYSPEDIAILGGGDDDEEEEDREEDIKPVFAKKSQARNMTEGGEGAAATHAYEKLASMDAGNDDLEDGEIEDDEFGGDDDPEERWTLRKGSAAALDVFARDFRDPVFSCLLPYLTTNLKHEEWPHREAAVLALGAIAEGCIDVVTPHLPELVTYLLSLLNDTEPVVRQITCWTLSRFSGWACNASAPNSCSEYFLPLMEGLMGRMLDRNKRVQESGASAFANLEEKAGRKLEPYCEPIIQQLVRCFGKYKNRNMTILYDCVQTLAESVGPHLAQPHLVNQLMPTLITRYQLIPDDSRELFPLLQCLSYVAMALGDAFSNYSQHIFGRCVNIIHTNLEQNANSNTDVGAIKPEKDFLITSLDLLSAIIQAIEGNKAAELVAQDERHFFELLTMCMEDSADEVRQSAYALLGDAAKFIFPQLSKYMGSIMPILTRQLDLDNIVDEDIDNGFNVINNACWSVGEIALQLGGPDMVVFMKTLVPALVEIITNPRIPPNVAENACVALGRLGIKNSDSLASSLSVFAEDFLATMEGVVAADERASAFTGFSLIVLKNPKAMESTLLSFFSVIARYQDLQLQSPVKQEVHDSFASVINVYQQMIPQFNEFLGQLKPNERQNLRTGYGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAD4</accession>
    <name>A0ABR3ZAD4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 4B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TIF3</name>
        <name evidence="5" type="ORF">Cpir12675_002449</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000047">
        <property type="protein sequence ID" value="KAL1897262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF11">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="84"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="31"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="152"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="39"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="56"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="193"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="248"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="280"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="306"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="365"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="478"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="519"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="532"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="567"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="615"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1897262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="624" mass="66973" checksum="58690B5149EF6EEC" modified="2025-10-08" version="1">MSLGDFMNDSAYGGSWADEVEDDIMTGTQALPVTERRTYGGGSGYGNSGGYNSYGGDRDRGERFERNYAPRNLGPQDIPDKPPYTAHLGNLSYEVTADNVIEFFQPSEIVSVRIIEDRENMRPKGFAYAEFKTPEDLKAALELDSTSFQGRSIRVKIADPPRDRPEGHSSGRDLDWTRKGPLADLPNTSNRNANREFSERRAPREPTEDRGIRELGTWERKGPLSPAVREDSAREGGRPQSNQNSSGERNDSFRGNNRREGASWGEGNRQPGGEQSENARPPRPERAPTAAERDNQWRSNMRPDNAVAAAATTEAPDSPATSTVPTRPLLKLQKRTAVDTAEDASPVVSSSKSNPFGAARPIDTSAREREVEEKRIKEKKEAEEKVKEAKEAKEAKEAKEAKEAKEAKEAKEAKEAQEAAAEKAAAEKAAAEKAEADAKAAAEKAALPASTVTPEKSYAKANAGSTDAPESKSSTGPRNREQHPREQKPSRAAESGNWRSSATRGNGPPGPRRGDNRGPRGGRQDGGANRGHRGDGSHRGEHRHGGNRGDNHRDIREQHSVPSTPVTASAPESGAAAAPPTAPPAAAAASASAAAPASASGPAEDDGWTTVSVPRGKRNGRAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAZ1</accession>
    <name>A0ABR3ZAZ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_002334</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000045">
        <property type="protein sequence ID" value="KAL1897479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43859">
        <property type="entry name" value="ACYL-ACTIVATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43859:SF4">
        <property type="entry name" value="BUTANOATE--COA LIGASE AAE1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="5">
        <location>
            <begin position="41"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="6">
        <location>
            <begin position="494"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1897479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="588" mass="65156" checksum="544A19CE5B785EDC" modified="2025-10-08" version="1">MSPLAERLGSILNHLKAGSGTDDFEHKHNLHTLSPTFFLPRAAAIEPDAEAIVHLTRNNQVLRRSYQVFADRACGLAHFFLKHNLKRVGVLAPNTPAFLECIYGVVAAGGVVVPVNYRLKEDDIAYIFDFAEVDAIVVDDEYKDLLGAYVKTHPKTRIVVDLDTATAEAGQCGPYGEAVLEGIEYDAKNNNEGWGGLEAQCKDEEDMIALPFTSGTTSRPKGVMLSHRGAYLAAMGGIVDNGLNVQDRRCKYLWILPMFHAMGWTFPWSVTAVRGTHYGLRKIDYPLIWKILKEEGITHFCAAPTVNTLLCNSPEAERLPRPIRVVVAASPPTAHLFQLMVRVALSHEKFKATSLNLLPRHAYGMTETYGPLTCCYELPSWDELPEKERFARMARQGHGFVTSLPIRVVKTDQPEGVLIDVAKNGEEIGEIVFFGNICAKGYYKDPAATRKLFAGGGLHSGDLAVWHPDGSAQVLDRSKDIIISGGENISSVALESMLVEHPSILEAGVVAVPDEHWGERPKAYITLKQSRHVDKTEFLEWARNHNGISKFMVPREVEIVPELPKTSTGKIRKNVLREWAKTGVSEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAZ5</accession>
    <name>A0ABR3ZAZ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Superoxide dismutase 1 copper chaperone</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CCS1</name>
        <name evidence="8" type="ORF">Cpir12675_002418</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CCS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000047">
        <property type="protein sequence ID" value="KAL1897236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.200">
        <property type="entry name" value="Superoxide dismutase, copper/zinc binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036423">
        <property type="entry name" value="SOD-like_Cu/Zn_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024134">
        <property type="entry name" value="SOD_Cu/Zn_/chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10003">
        <property type="entry name" value="SUPEROXIDE DISMUTASE CU-ZN -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49329">
        <property type="entry name" value="Cu,Zn superoxide dismutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMA" evidence="7">
        <location>
            <begin position="5"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="256" mass="27408" checksum="282DBED503D8D2BD" modified="2025-10-08" version="1">MTISEPIQVRAYDMNFLPMVCEACVKSVSESIYNLGGITNVDANLKDQQVLVEGTAAPSAIVSAIQATGRDAILRGSGASDSAAVCILESFETEAATQPVPEDGRQREVRGLARMVQGSSSALVIDLTIHGVEPGLYRATIREYGDLEAGVSSTGLVWGSKENPDAPRGFISTVTVDESGKGAVYVDKPLQVWELIGHAMVLTRQGEEKVLENDANTVVGVIARSAGMWDNDKMVCSCTGKTLWEERKDEVKKGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBJ0</accession>
    <name>A0ABR3ZBJ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_002123</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000038">
        <property type="protein sequence ID" value="KAL1898036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06467">
        <property type="entry name" value="p23_NUDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037898">
        <property type="entry name" value="NudC_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356:SF3">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356">
        <property type="entry name" value="NUCLEAR MOVEMENT PROTEIN NUDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="4">
        <location>
            <begin position="22"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1898036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="188" mass="21116" checksum="857866A23EAF2B31" modified="2025-10-08" version="1">MSDNEPTSAEQAAARAQEAAEQADLPYKWTQTIGDLDVSFTVPGNLKGRDLVVDIQKLKLVAGIKGQELVISGDLPHAILVDDSTWTLSPAPDGTKTLEIHLDKQNKMQWWPHVITSAPKIDVSKITPENSKLSDLDGETRSMVEKMMYDQRQKEMNLPTSDEQRKLDILKKFQSQHPEMDFSKAKMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCN9</accession>
    <name>A0ABR3ZCN9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000032">
        <property type="protein sequence ID" value="KAL1898413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025337">
        <property type="entry name" value="Questin_oxidase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35870:SF6">
        <property type="entry name" value="MGS207 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35870">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G03330)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14027">
        <property type="entry name" value="Questin_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="411" mass="46990" checksum="2C2FED2C0613C2BA" modified="2025-10-08" version="1">MTGILGYVPLVGRLVNPQAQSIDIPPVPHQDIETMEDHNSRSLKHLLRANHSNYACLFGAEMKLQNPLGPLLCSAYAMGANNVQLHALYDEYVKVLGPWEDSPSEMIDEDWQDFYGNPKYQRATIDYFEDALVMTFNYDWRKLVGTFLFQAPKPLFNGLMSGLGNPLVHLANSFQINSKELSMEAFALSSAEYDYTAEYMNSKFYAEPSSRSSGSINDLLEQVRQDDRFNQIFSEPSLDKIPQLFQEHEALMMEYWNAWILDDLTKQFRESQEVAVALLVSSVKRRSKSHSKALAQVLAASHAIRIILQFIPKKNHIKLVRSWWLMTLAVYVSNLRPKMDTNYADVGELKGRNWSYVENMALESPWFQDASYVNSLRSMRDIAKTWKDADEKILLAAVIFADEFGGWTPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD85</accession>
    <name>A0ABR3ZD85_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000034">
        <property type="protein sequence ID" value="KAL1898325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="126"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="188"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="267"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="374"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="397"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="443"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="493" mass="51146" checksum="8DBFA9C22CB4AF92" modified="2025-10-08" version="1">MDKAKSMFKDGWHPEKPGQTFRQQVNGLMGRDKKADEEHANRHVTPVSQLRDPNSFAPPPKRTEGSIRPPLSPPPSSSSRKPIKFQPGTDLYSADHKVIERPSHPPTYQVATSPPLQITQGYGEDSPPATSPAARPSLPPRLPPRRNTTSSVASSAVSNDLPPPPPPVRNAGNVAIQPPPPPPTRNVAAAMQPAPSSAMSRLASAGISVPSFGIGSSPSTSGGAANEAMAPSDASAANSATSNAGGTMDKLSARFQRFSPMSSRTGSPVLSPSSTSTAVAPPPPAQGTTLEQKQAALRTAQALNKDPSKVSLSDMRSAASTADNFRQRHGDQVVQGAHKAQEANSKYRITERMGQMNQKYGLSEKASGLAARFSGSGSSETTAPTATSTPTLPPPNTHSHSPTHSTTSSILPPPLPSSTRTQQRTSPPDTSPRPAIAPPPVLSPSSSPAAFSAVGKKKPPPPPLKKKPAGLSGAGAVVGDVPPPLPMSTKPAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZET6</accession>
    <name>A0ABR3ZET6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-binding transcriptional regulator ume6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">UME6</name>
        <name evidence="5" type="ORF">Cpir12675_002071</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000037">
        <property type="protein sequence ID" value="KAL1898054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF12">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="43"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="137"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="7"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="137"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1898054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="753" mass="81262" checksum="8E9DC45D27D8248C" modified="2025-10-08" version="1">MAVAPMSSASAKAKASKTSSSGAATGNGNGKSKTQMHRRSRTGCYTCRLRRKKCDEGTPLCTACKHLGLTCEYKRPMWWSNNDMRRKQKEEIKIIIKRKKMSEKSARPMPDSSMSVPMAMSIPMSMSIQLPMTTSSPPLLSHSVPTSTKFSDPMDRDRSSSIDSQFSVPDPATGAMSMAGFSTAGFSSPPGIMVFRNQPSAAYCNPELLFGAGPCYAPYEIDIKTERQMFVDDVPTMRESTVSTFSSFNTPPQVGGVLGQDWESSQHAFTESSEESLGEGALDCNFFNFEGDISVIPSQTSCSTLAIEVELDENDQVLLDHFIKAVLPTIFPILDSSQHMPSATDLILPALQANKCYLHCCLSIAAQHLKATQGANPELDEAITNHLCQTVSMLCRALSEDEAHGEVLDVTLALVFFQCVVGTIDESLSHIPWHQHVQAAMSVASKLGLPASDPASQAEGIINEIKTEESSAPSTSSLSDAAHEPFASAFASTSFNTTLLSWIDILGATMKGQAPAFAHTYREKHLAHPASSLGLRDLMGCEDRVMYLISEIACLEALKTDGMDDISICQHVHVLGDQITMTEQADGAAATPKSPYTISGALSPQQLLRNVTAAFRLAARIYLCSLVPGFAPSQTSCIGLVEKLTNVLQFIPPGYDRSLAWVYLVGGSVALPQSSFRAVFEGRMGAMGEQAHMGAISQVVVILHEVWSQTEAAMLVQAQSAASGTCGPHGSEALPYIHWRDVMAVKGWDLLIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEZ1</accession>
    <name>A0ABR3ZEZ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sec39 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_001697</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000028">
        <property type="protein sequence ID" value="KAL1898944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013244">
        <property type="entry name" value="Sec39_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40787:SF3">
        <property type="entry name" value="PROTEIN TRANSPORT PROTEIN SEC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40787">
        <property type="entry name" value="SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08314">
        <property type="entry name" value="Sec39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045831500" description="Sec39 domain-containing protein" evidence="6">
        <location>
            <begin position="26"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="domain" description="Sec39" evidence="7">
        <location>
            <begin position="11"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="779"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="858"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="797"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="858"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="877"/>
            <end position="892"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1898944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="923" mass="102822" checksum="938153F7C33C2641" modified="2025-10-08" version="1">MDLALSNAKVVLLAVHLASIAQVDALTCLISHNVTVLRNDIALRILLTFLPEEVSPALYVPLLKELDSGVLEKRNECIDASFVQSLTDEEAVKKGRKLKLFPIVWDSPAVDVQGNHVGLFLLKRAYQIGKTPRILGLLYELLPPFFDQFPPLRPWYISQVLPLIRRNFEYYPQSPANITLEQFQDLSETQCVELLLSQTGINADERTLIGRDLRGMIGPWLQSSHHLSWPDEDGCIVCPAFVKVLEWILHQTGKSWPVAIQALVQWNGFDDIETGDFEMHLSVDSNQLRRLKQMYLQAAIGCVYLMPEGKIPALYATYEVFAKVTRILGFSELPTLEQASSNLEILESFQDSSFIVPKLSSYMRSGFLSSSNPLTIPSQTSVHLLQNLCISAFLFGRLGILQSIKNMGDLVFFSDSQGQQTLVTRYVAAIANRVSHNQEADWAKAREELIWLRSWGQEGKGRSVGVFGSVGKEFIECEFLKALLASTRHYNLARFLYEENVPRPLDADVLKRNIVSQALNAYDHATNPNRTRGGLKKCDEIIHAFPLTIGKNSSEMARIEALLKVTHALSEYSLVLKKGEPFTPVILRAHEDPIFILERVLEQNPKSYTKLQDFVDIGTDLVHAGLCCPHSKKLSHQSTPLEREETAFLQRVEWRVISMCVQAALEEDDFETAYSYVVNRLSTVTSPEIAGTKDSYAWRAALQSGNYIRTPRTVRPTHVGTASVNPDIRHLEQRIECLSTALRIAPASQLEEILQVFSQCEEQLNTSLNAEAASEAAWEASGDTSAIPGSFVPPPHLDLRRTDSIRSNRSTRSTGGNSGHVEGKKPEESMSLFDLSKATARLATRNFTALSGFTAGTNSPARSMSPSMANEGATGYEDARNDDAHRTRKRDQLRDAAVGTLVSGVGWLINAPASQQKEDGETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEZ4</accession>
    <name>A0ABR3ZEZ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein transport protein sec73</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_001708</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000028">
        <property type="protein sequence ID" value="KAL1898955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF405">
        <property type="entry name" value="ARF GUANINE NUCLEOTIDE EXCHANGE FACTOR SYT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEC7" evidence="3">
        <location>
            <begin position="604"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="889"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="773"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1185"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1253"/>
            <end position="1306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1329"/>
            <end position="1388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1412"/>
            <end position="1550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="210"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="496"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="574"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1188"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1257"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1288"/>
            <end position="1306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1340"/>
            <end position="1349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1416"/>
            <end position="1425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1432"/>
            <end position="1447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1448"/>
            <end position="1458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1540"/>
            <end position="1550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1550" mass="170654" checksum="A855FF5BB0247DF2" modified="2025-10-08" version="1">MASESDMRRHTSQPQSLTAADASDHHLGQLLEKGSSPKPNQDANGSEVDFYSGQVPSPRSHLNTDSNSASGTASYSAPKALNDALVIFSQEDNHNQSSQLDGPLQLQLRLPSSRLSSFSGAAGQLDFNNEIIATPHTQPHNTVAIENTVNTDTSGSNPAASHASRANNTHEQDFSRGRTTHRALHRTNLAASTCQHPAASTRRSHDIPQSSFSPSSTAASDNTKNRRFSLRFRNASDSQLPLRLKQLEESPPPPLPAPPPGIITTAPTGDFVAMQKKPSRLRLSRFRLSKNASTNTLKKPSPSRLTTGPPSASDPSGPGPSSGSLSRKPSRALNPSANLDGNLQTPMSSSPPSADTSFDSIEPISSSPAPTLDGQAGDTTAFPTTLNRRSDSSGPSDVSLADPKPQSVNQRSSSSIFRLTRRKTRAAEPLFPTSHLPQKPKVSLGDDSHFESDTSNSLNIPNNGSLSFSPNTDRPVSRSKTYAPHTPRPRSVRSKTAAAPSLSPSPATALFRPQSNHSGRSSPIRSQTRRGRSSTLSSLGHDSNDENPAPPSSRPSFNSGRKSFGDLFGLGRLRQNSDATIGRSGNLTPITPGSVPSKNNSLQLVREEFSLPEKREDDTPVKYLARVEGHIPRGSIASALSKSSDPFYSAVLRSYMRKSKFFGDPMDMALRKLLMEAELPKETQQIDRCLVAFSNRYHECNPGIYANPDQAYFVAFSLLILHTDVFNKNNKHKMQKSDYLKNTREQGVYDDILDCFYDNITYTPFIHVEDDFDSNSERHNQNKGRRRPIFPGAPPEIPKKSKEPIDPYTLILDGKLDNLRPSFKDVMSLEDHYTYLGTASRLDLKELQKTFFRTGVLQIVSARSRPDAFMTEKTASNPQVAHPGIVDIKVTKVGLLWRKDAKKKKTRSPWQEWGAILTGAQLYFFRNTTWIKSLMHQYETHMKQGNDDVPVIFKPPLEQFKPDALMSTDGAVALHDMSYKKHKHAFVYVRHGGFEEVLLADDEMEMNDWLAKLNYAAAFKTSGVRMRGVVGANYDGQSRRAIRRLDSADGAQVVQTPSGEVSITRGRIDHKMAEDISAARRQVILDKVVEADERLTVAQKLLDLQLRNARHLQIMAPIQVKTREQVLLSAARMSAQLKWTRAEIWRLKCHRDILMQDMEEERLLISPPGSSKLGSVQEDLYATHEVSRPTTPSNDSHPSRSPITSGSLKASVKVQTPLSLSLSPQLGVSDLNLSSNIEAEYDEATASPTAAHYNFYPSESTSSPNEESGAAERPLQATSSSSTTPPQRKSDADKLEKESGDDNDIVEHNLLEQAGLLRSSTTRNWKCTTSSVQHGGIDVDPEKEKADRSKIRRSLQRTLREGGTRSKKGKEPVQVTDEEERLARGNGSFTVHGKKASVINFGSELHNLPSKRTETDLSMSPSSLNVVEDDDFHSARGDFDDWRERRGSTASASTATARSFRELHRKYSTAHPPRAHSTPGKLSAPSDTESEVAVSFSEGQRTPLPPIENSSDIESDAKDSEFDEDHVQNQAQKQEQHPSENPPQDVPEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF68</accession>
    <name>A0ABR3ZF68_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator of ribosomal biogenesis proteins</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SFP1_2</name>
        <name evidence="2" type="ORF">Cpir12675_001459</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000023">
        <property type="protein sequence ID" value="KAL1899343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="333" mass="35142" checksum="34FDA1F03D2E7810" modified="2025-10-08" version="1">MLSSWFKLSQSSSTDNKASSSQLGPSPPPTAPRTSGALNAASTASLTTSAFTTPSSATTSPTATATTRKARAKKAKANPKCQSTGSAGTAHLSKSKPKKSHSVFDLPSPSPSFPDSPTSPAAESANPRVDRDLTESSDNVPVARPSRHRHPNRRYSPADDPKLLTPPSISPPFTQTQVLAQAQAQAQAQAQASSASRVFGAEFDQLDLEPRYPSHFINFKSSFEIRAENRLESLFSSYLASQYPDSTNIPALSGDQHRHHLDCNMNLGVPMDSPIGRSRQDSFVSAGPKAIAIGGGAAAAAGRNRRESLQNTGSFMGGVSWGGMSLGSFVRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF93</accession>
    <name>A0ABR3ZF93_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001409</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000022">
        <property type="protein sequence ID" value="KAL1899373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057218">
        <property type="entry name" value="DUF7896"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42031">
        <property type="entry name" value="KEY LIME PATHOGENICITY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42031:SF1">
        <property type="entry name" value="KEY LIME PATHOGENICITY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25438">
        <property type="entry name" value="DUF7896"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="106"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="717"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="770"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="1128"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="1155"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="1187"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="1248"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="629"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="833"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1217"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1303"/>
            <end position="1333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="833"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="845"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="901"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="928"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="951"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="969"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="984"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1006"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1311"/>
            <end position="1320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1323"/>
            <end position="1333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1333" mass="148055" checksum="61AE82FEDA731BB8" modified="2025-10-08" version="1">MLRIKLRGLEQYMERNGIRQITELSEAEEARMLQYRCEVFQSAIMEHGINIADISFVESLKHQPAHDSPSDYGTWLAQNMRENDTMARSARMGDYASQRQLRFSSFKCSNETCIYYVYGFATADDRDRHVKEYHVPSIKRDSTLSLGTPTLPFPDYGPSSSRSVPDSRHPTSLKAPGKLQSGPQLPPLNIGSSSAYEPRHRSTTSAHPPHNDFSALRGGHDDESASDLASSKNCRRTPTSGTVEAGGDIKYMQEIGPCLRCKLTNKNCDLADPCTSCANPAPNLEEDYWRSIGCLRVNSSLGCLAVKMLPNWLSNKQTRSIVVAPDQEQSHALHDYFERMYRAPSPIIENVLAGLDWKDSFWLTEIISNPPPGVIIAPLKIQAPQIFTILLNSQNAHAGSYNFLDVLRCSQNLSGSRSEEQKTLPVLYNAKVLLRQTLFFDLLQQEPVIVPVDRESQPHTLGLPEAVDSERYLKLVYDALVSFFESFQQMTMHKGPLTARDWFAGFFSICLFSIVKYILVERVEQGSAAPGRIPAWRSTLSPKTVGEVQSINDIYTAIVTIFVRSSPIIQEDGRVSMDTVDGRIMGRIDAIMLRGEWHSQGIRSIADFLYNLGSRNADSFGFVRAPSPTNSFRSACPPSAKPAEAQRPDSFRPWLTSASSNVESGEPGRSGHDAYVESPKTFDSPRSSRIRSESLYSKGAESPLRHVGFQRPPYRKIRCEKCNEYPEGFRSDSEYRRHFEAKHGAYRKAWMCVEPSNILPDMVKPTNPIHSCRLCHKRHFKSYQSAVIHLQRHHFTTYTLGRQRVGGSSSEIVPEHLLKDWIVETRCISESGDADDLDEIMDPDTPNTKQQPYQSHAPFSASLPPSAQGPLSAPHVTESQKPIFPPRSHSHGYPFPPRQPSGESSSNSAPSHLSRYESPSTLLPPPRQSQAPPQHAPSQQPQEPLHSGGIQLPPLNATLPPLQPPPAAPSHSSSYHSDSTYSSQGGPSSHVTTQTSLSPALYSQHHPGHSHSHAHSHSHSHSHSAHYIQQPPPLQTKFGPQESPSLVYPHSGQSVPPSPFNGAPLLQQSLPPTPSDAMPQPRVIGPPPAQYQSQPARSGLNLLQPSLGGMVSHDEPPCELPKTPENRSRCPFPDCGRVFKDITSHMLTHQEQRPEKCPIESCEYHTKGFARKYDKNRHALTHYKGTMICPFCPGAGTGFEKAFNRADVFKRHLTSIHHVEQAPPNSRRPISGGSRPLSNNHSTVNTEAQCSICHGRFTTAQEFYEHLDECVLNEIVPGSQSPKSITPTASVGISVVPRESFIGRGSRDWSDTQSVHSQGSVKGKGKLKEKKRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF94</accession>
    <name>A0ABR3ZF94_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Autophagy-related protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ATG2</name>
        <name evidence="14" type="ORF">Cpir12675_001739</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) = a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out)</text>
            <dbReference type="Rhea" id="RHEA:38663"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine(in) = a 1,2-diacyl-sn-glycero-3-phosphocholine(out)</text>
            <dbReference type="Rhea" id="RHEA:38571"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out)</text>
            <dbReference type="Rhea" id="RHEA:38895"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Preautophagosomal structure membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ATG2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000029">
        <property type="protein sequence ID" value="KAL1898736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026849">
        <property type="entry name" value="ATG2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13190">
        <property type="entry name" value="AUTOPHAGY-RELATED 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13190:SF1">
        <property type="entry name" value="AUTOPHAGY-RELATED 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13329">
        <property type="entry name" value="ATG2_CAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0072">Autophagy</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="150"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="265"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="358"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="422"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="570"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="791"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="975"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1701"/>
            <end position="1732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1786"/>
            <end position="1808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="268"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="391"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="570"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="603"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="978"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1006"/>
            <end position="1016"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1898736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="2230" mass="242525" checksum="F55915D08A4672B9" modified="2025-10-08" version="1">MFRAFSGSAVPKRLLRHALSRLDFLDTDAIDIDNLDLAIGRNTVLEFRDVGLRLEKLELILQLPPALQIRKACVRLLKVSIPIDFYTSPICVSVQAIEVSVSLADEPIYTPQDATDTAAHRGHNESPLVPNVVDLAQSFLDMQSVTEKRELEHALSEKSSPSALPVRGADGHGEGNGDGEDDESGGETQYGTGQPLSLPGFLASFLQGIVDRVEVTISDVTFKFDTNLSTNDNHYNNTASQPTETISFMLQLDSIEIEGVTSSALTTSKPSNSNDSNSQSSSPSLHSQPLQRQGKRHVAINNLHAYLVSDPRVFSLFTAPSPAPSSVQSGALSRDADFLTTLVPHSYHGEDFLTGSPAASNYSLGHDPQSRLQPALGLSPDQIPDEDPATPRQSRTNLSEHSTIGSTESLLPFLDLSTANQSPARVMDASGRTPTINSQPPLPDSIHLLIHDSDEDIGSHNLPSFSRSSSSSDVDEDLTTSRMFTHSHAESLYMSAISLPHPIVPEHEPVSWIQEGPAVEPYSNYQSQEDSSVSATIIDSAAMDPGLTEALSEQVYDISQGFPLEQSQVDLETEPPSNQTSISAAPQPAYDKSIHMPGGWGEASTSELGSSTNSQTIGNSRYISAFKTLKQEAADSTAPKEFLIPEVDVVEANTPVMAKTAQDEAARPPTPQGPPRIAKEIISLDKVSIFIPSQPSVEASAEHPQMQQHISGDNLDDSIHLGGPGAYFMQNTFESLPDISVDDYKAYMKSTKPPESVDIELSPLKIQFDISLGFLIASMLSKLTNAFSHTSTLNETGHSSKQRQSTKSKEKDPLAFVPNIKFALEWISLSLVDRVDGFKCFSDSVKRPTTSNLAEPSVLLRADITDVAAKMRQEQDKEKFDLSLGKVSFGYANEHIVWFEHETKLQASSMQDSSYNESADIQVSLSQNAVESRVMVLTLPLYAKLNLGKLDEFFDHFGGVSEFADMGLSMISQLPSRHQPETRTKFQPRERSASATTPRMRPRGVRFGETDNKDKVSPSGPKVDFRIGGCRLRLVSQICRFDVDTTLVKAVVRNEGIGAYISQIQITGPWTHETQSVPMTLQLNDTRVDFLGKPLESDISRLLEMLMPAKSKFKDGNDLMVDRLFAQRRKGSLLRIKTKSVQLRLGSLALLKCLSDLGDEVGKLAPLALMFPEDDRPGILVLAGVEETQISADVGGKLGIFHCDLRRLEVAHVGFPSLLSVGVGVIRVDRNGKETLVDSVRGIAVPSGLSPESSVAVRVRMIGDDFEPVIRVRVQDVAIEYRVPMMMDLLGLEEDTTPQEFEETLAASVANLGETAVAGLGIEMAPATNSKGKTKAIKPLVIDLALRDTLIGFNPLGIPAKMYAVLGESYLTTTLPENGNFDVKVNVAKAWLMLVDDVEVLTAIEDTITCHNDHAESVLTAGLSKRGFANISYISSSVTTVKSAMLPESDSRQILIDMQKALFILETCADSTQTLIALANALSPPTPPSTEIKYRTAMEVQDLLASISGDAFGQAEGDYDFENDFGHVSSYESGDSDYDNMSSLASSTADLRAGLSENYGGDSGSPGLIGPSMKGEKLFDVASMTDSITTTQDTRDGVLLGHKNTDSFSQEEPYGTSSELVFDENYFEHKAEVAENARLWDAAKGSYAVAPRNLVDASPVKITVREVSVFWKLFDGYDWAATRDVISDAVLGVQKKAVEHKDRDAAHGRNVGSAVSATEGSKSGIDSDGEGLLETDTEIGDFLFNSIYIGITPRQDPHELTNAINCELGGDTGDTESIATVTTQTSASTIRPGNSERGVPRESRSAQHQCHQQKLRLQRSKKHKIAFEAVDIHVDIAMLPAGSGPTQSCIDVRVKSLDVIDHMPQSSWRKFATYDRDAGERELDSNMVHLEVLNVKPVADLAASEFVISVEVLPLRLHVDQDALDFITRFFAFKDERTPIHQSSGDVPFVSRFEIQRIPLKLDFKPRHVDYVALRSGKTSEFMNFVTLQDTHIELRRVMLHGVAGFDRVGLMLNDLWTPDVKRFQLATVLAGLSFMRPLVDVGSGVKDLIEIPMAEYRKDGRILRSIKKGAISFVRNTGTSVVKLGAKVAVGTQNALEGAEGLLSNNGQKQQQFATTPSGNIDNYTANDDRRVISPYANQPLGVVQGLRGGYTSLTRDITMARDAIVAVSTQVMESNGPAGAARAVLEAAPTIIFRPAIGASKAIGQTFLGVTNTLDSVNRGRTNDVSIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFG1</accession>
    <name>A0ABR3ZFG1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Uridine kinase</fullName>
            <ecNumber evidence="5">2.7.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">URK1</name>
        <name evidence="7" type="ORF">Cpir12675_001642</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>cytidine + ATP = CMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>uridine + ATP = UMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16825"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the uridine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.48" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000027">
        <property type="protein sequence ID" value="KAL1898982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004849">
        <property type="term" value="F:uridine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02023">
        <property type="entry name" value="UMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000764">
        <property type="entry name" value="Uridine_kinase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004018">
        <property type="entry name" value="PRK05480.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00235">
        <property type="entry name" value="udk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14681">
        <property type="entry name" value="UPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00988">
        <property type="entry name" value="URIDINKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="47"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="477" mass="54316" checksum="79A917AAC432687C" modified="2025-10-08" version="1">MCNSFQLRTTNFSLNLAPTLVSVLDMDNTQEDATIIKRTMYAPPWADVSIIGIAGSSGSGKSTLSQAIVKKLNLPWVVILPMDSFYKPLTPEQSKKAFRNEYDFDSPDAIDFEVIIQKLRDLKAGKRAEIPVYSFSKHQRLPETTTIYSPHVLVLEGIFSLYDPQVREILDMMIFCEADLDLCLSRRLLRDVEERGRDIEGCIKQWFSFVKPNFEKYVDPQRKVADIIVPRGIDNKAAMTMMIQYIEKKLVEKSTHHRAALKELEMHADQYPLSPNVRILDQTQQLIAMNTIIQDIDTSPEDFIFYFDRLACLLIEQALNKVRFLEKNIETPDGGQYQGFEIKGEVSAVLVLRGGSAFETSMKRVMPDCKFGRMLVQSNMSTGEPELHYYKMPHDVAQHESVLLIDTQMASGGSALMAVQVLIDHGVDPKRIVFVAYSAGRMGLRRLSMVFPDIAIVVCSMVPDIEERWVEARYFRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFP6</accession>
    <name>A0ABR3ZFP6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA-directed RNA polymerases I, II, and III subunit RPABC3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPB8</name>
        <name evidence="5" type="ORF">Cpir12675_001667</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the eukaryotic RPB8 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000027">
        <property type="protein sequence ID" value="KAL1899007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005570">
        <property type="entry name" value="RPABC3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10917">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10917:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03870">
        <property type="entry name" value="RNA_pol_Rpb8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000779">
        <property type="entry name" value="RNA_pol_Rpb8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00658">
        <property type="entry name" value="RPOL8c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1899007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="152" mass="16851" checksum="34B8375984F062D6" modified="2025-10-08" version="1">MSGNGSDATLFEESFNVTNFDQSKYDRVARISATSSDESTILTLDINVELIQLGIGQNMTVMIATSLALDGSKSEEKGWRDTSKGNQPAEPTLADMYDYVCYGKIYKFEDGDDGKNIKVYASFGGLLLSLNGPYKKLTSLRVDYIYLLVKRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFW8</accession>
    <name>A0ABR3ZFW8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Pre-mRNA-splicing factor cef1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">CEF1</name>
        <name evidence="12" type="ORF">Cpir12675_001371</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CEF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000021">
        <property type="protein sequence ID" value="KAL1899603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11659">
        <property type="entry name" value="SANT_CDC5_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047242">
        <property type="entry name" value="CDC5L/Cef1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021786">
        <property type="entry name" value="Cdc5p/Cef1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047240">
        <property type="entry name" value="SANT_CDC5L_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45885">
        <property type="entry name" value="CELL DIVISION CYCLE 5-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45885:SF1">
        <property type="entry name" value="CELL DIVISION CYCLE 5-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11831">
        <property type="entry name" value="Myb_Cef"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="11">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="10">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="10">
        <location>
            <begin position="53"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="11">
        <location>
            <begin position="57"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="109"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="220"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="424"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="737"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="125"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="239"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1899603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="780" mass="86847" checksum="7F3A31995CE8D311" modified="2025-10-08" version="1">MPVVKGGVWTNIEDEILKAAISKYGLNQWARVSSLLARKTPKQCKARWNEWLDPSIRKTEWSRDEDEKLLHLAKLLPTQWRTIAENVGRTANQCLERYQKLLDEAESREGLSLTGADGAETKAPSADDVRRLRPGEIDPDPETKPARPDTIDLDEDEKEMLSEARARLANTQGKKAKRKARERQQEESRRLAALQKRRELKTAGINIKVVTRKPGHMDYNADIPFERKPAPGFYDTSEELSRNEKERANFDPKKHQLASAKRKGDEDDEEANRKRRKNEKKDENSLSKAAIQAGKMQRIREAEQSSKRRALNLPTPQVSEGELEEIVKMGMLGEKASSMARESDNDATRGLVSDYTKLNNSAPIRTPRVAQEEDHIANEIHNIKALTNIQSSLLGGENTPLAEGSSSTGFDSAAPRKQVVATPNPLATPLYTGNLDATPLRPGETPMRTPRDRFALNTEGGSLIPGATPHDMKVHNLAVRQQLKFGLASLPKPKESEWELEIPEEQAISASTGDELVEDSAERDRRENERLQAIEALERRRRTQVMQNNLPRPLVYDCSSIAAVTKDVNPEELIAYETSLLVANDLAKYPVPGSTLIGKAPALIAILDADLENARMAIEAETQPLPDREVLRKTFDSRNSNTTLLGLGCYESDDEDGVDAVVRRAITSIQELLVEEAGRSAKLEKKLSLHLGGYQNRQKTLGVNLAKATAAAREASNVLSAMKLLALSEETAINRRLDALREEVSVVSRREREAQEDYRRAKGELADLRAAVKVNGESAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG28</accession>
    <name>A0ABR3ZG28_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Squalene synthetase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SQS1</name>
        <name evidence="4" type="ORF">Cpir12675_001351</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000020">
        <property type="protein sequence ID" value="KAL1899673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="entry name" value="R3H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001374">
        <property type="entry name" value="R3H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051189">
        <property type="entry name" value="Splicing_assoc_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14195">
        <property type="entry name" value="G PATCH DOMAIN CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01424">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00393">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="R3H domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51061">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="R3H" evidence="3">
        <location>
            <begin position="494"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="domain" description="G-patch" evidence="2">
        <location>
            <begin position="616"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1899673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="659" mass="73347" checksum="B34A53E827928129" modified="2025-10-08" version="1">MRKNDRRKRRQFLSNGADTSHSTKKCRQVHRCDYSNYTLQDEAHNTSSHALTVTSLWKQPVKFMSVGYSQPLQDLIILQKNLDPKIEPPGKPTVSIASTAEEKAQVDCLLPADSKEIKRPVSPAVSETSSIEVILFQGRKAVARQANSYNTSGAIANTSCGSTYALPSTVEKNTVPQQQSFGKSEKNDPLDLNDITKEIQAILDNNLNSINISDNDAAMVKPSHRRALRRESRNRKKQKKRSHSSSGSLSNPISLFSAGIEDDSDAFDSDMIIDDYMDNLAENGFEFEPTIWSQRDLGGEEGDIFINTEEKSTKDPSDGESVDGRASKSNIFQPSSQNTVEIFTKFDSSPAADDLGFEIDEFGIDTTSSETEENNNNINGDDEDEDEDENNDEDKDDNKVNNPRGFDEMSQNDDFFNQDIISVFPNHIIKRKGKGSINSMPFLDPSLDPDIKDILIKSINSNRAKKTARKKQRELLRAQGQLGKITSNDLSVKYPSGMQFEEIASEFWEFLSSDNEQFTLLPMAPSFRKGIHDIAHKLGLVSKSTGKGNSRRPVLYKKGNPVYIRSRFDQIMLLAGKRHFKVKSASMKGAVFSGSSRQTRYQEGEIIGGSLPELGNDNRGHTLLQKMGWSRGTALGAIENKGIMEPVMQKMKNTKAGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGI0</accession>
    <name>A0ABR3ZGI0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Extracellular serine-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001563</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000025">
        <property type="protein sequence ID" value="KAL1899279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00920">
        <property type="entry name" value="Cupredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052953">
        <property type="entry name" value="Ser-rich/MCO-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883:SF15">
        <property type="entry name" value="EXTRACELLULAR SERINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883">
        <property type="entry name" value="SERINE-RICH PROTEIN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045287110" description="Extracellular serine-rich protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="189" mass="20214" checksum="CDBF2DB516740727" modified="2025-10-08" version="1">MKFGQTYSLILAAVATPVLGSPVADSEAQGPSIIKVKLGAYGFEPHEIQAKVGDSIQFHFGQGISSVVQSDFNTPCQPLDGGFASGPLFVDTISSNGESSHVFEVPITNSDPIAFYNGGKGKCHLYSYLGVINGVEKNGQSYKALRAKTRTSKPREASHDPDAAHGGEIKPNPDFVGEDREDQEEKEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGL0</accession>
    <name>A0ABR3ZGL0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000024">
        <property type="protein sequence ID" value="KAL1899322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="415"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="488"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="508"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="521" mass="56396" checksum="3843E48600742F48" modified="2025-10-08" version="1">MESLHQDTFKCQAPASTPSDYAHLGTGSRSPMSNATAALASTPRSELANMSPFDSASLSSPSSLESLSERLDHIENRMVYKAMSSKTYSAIDEALGVHEADSSRMYQHEQADVPTQNFTMAGDGEWFPGVQTPGIEAGIWDADPLNVVGSGTGAKGSEKNDRSPSSTQASKQKDSEALGKAEGFKATQKKKSPTHSRSSDPDIFKHLLDRMRYWPEQDRAFSRTVGLFGFLVFMKTPYSRNMTRLGLMSVMACAWPLETAVLLRKVSTKLGWELNGLRDWWRRELAKNNSDDGDGDDFVKVASIPNVQVLEDGMEVEVMDSETFGTSEDGVSIMSPGMKKGESRAINKQANASRAKKEKKQANDEEWQGISISEMKEAIKNKVGKATEKLGEVVQETAGHMEDDLASARRQLQHVSARSISAHEKAKAEFEAQAQPPSDKNASGLFGILSEEEAASGKRKNGAVEPSPAFTAPDMAVENAPAELFGILGSDSKAQDGTAPPLAVGQGKKAKNVAKKNKGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGL3</accession>
    <name>A0ABR3ZGL3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator of ribosomal biogenesis proteins</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SFP1_1</name>
        <name evidence="6" type="ORF">Cpir12675_001458</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000023">
        <property type="protein sequence ID" value="KAL1899342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051580">
        <property type="entry name" value="ZnF-Chromatin_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057:SF0">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="163"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="362" mass="39120" checksum="292CD986087BA784" modified="2025-10-08" version="1">MAMHGTSPFGAHQSPSYHSSSYLPKLEANFMKDFQCCGRTLADLHDLLQHYEEAHTNNASPTARNPPAAFSQFARLGGLPASVKNADIRPNQLGGLQQFGGPAQLAQQARQPLSGMSSLNMLGQANLQPTSNLQAMALSEDLGDIGDMEMEDAVGHMEMDDPQQQQQQQQQQRVIQQTRQMFGQGAGRPQIQLNSGITHGLRTSQPTTPAVQSFGLQHNPTVSSVNTPTLSTQPGGGMFPKRTSGVAFLQPAGMANEDMSMMDQDFSGMQQNNMTSTGGMDLNAMGIQDDGNCIPDPGKNLNSGGLLAHQKILLAQLAMEQPDFQSKAPFLQRLGLLPEENKPFKCPVIGCEKTYKNQNGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGZ8</accession>
    <name>A0ABR3ZGZ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">WD repeat-containing protein slp1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">slp1</name>
        <name evidence="10" type="ORF">Cpir12675_001456</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat CDC20/Fizzy family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000023">
        <property type="protein sequence ID" value="KAL1899340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033010">
        <property type="entry name" value="Cdc20/Fizzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056150">
        <property type="entry name" value="WD40_CDC20-Fz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918">
        <property type="entry name" value="CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918:SF8">
        <property type="entry name" value="FI02843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24807">
        <property type="entry name" value="WD40_CDC20-Fz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CDC20/Fizzy WD40" evidence="9">
        <location>
            <begin position="270"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="322"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="398"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="529"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="149"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="33"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="64"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1899340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="589" mass="63945" checksum="0B1DADA182A82B7A" modified="2025-10-08" version="1">MTMTTPGLSTPIKSHTGMFSNRTAENRLPLTPSPRQRTVSINLESSPSPFTPDKPSNRTLHRGNLTSQFKRASVNQRDSPKSNIAAGVSTPRRALELGLSDFQLYGTGPRTPGSARAKKVVRVKAAPKTTITYGADRFIPNRGASSAIANAGSSKIDKPRSKKSSRSGGAASGSDILATATDDAIAAFDSLNIEDDEEFVRTTPRTAAYQDTLAKACDVDLSTRILQFKPAAPESSKPIDLRQQYNRPLKPTTNTAQFRRRIATAPERVLDAPGLVDDYYLNLLDWSSGNQVAIGLERSVYIWSADEGTVNCLMETKPDTHVTSVKWSGDGAYVSVGLASGEVQIWDVGDEAKIRSMFGHETRVGVMGWNKHLLSTGARSGLVFNHDVRIAEHKVAELVSHTAEVCGLEWRSDGAQLATGGNDNLVSIWDARSLSAPKFTKTNHKAAVKALAWCPWNMNLLATGGGAYDRHIHFWNTTSGARVNSIDTGSQVTSLRWSPHYREIVSTSGFPDNALSIWSYPTLVRNIEIPAHESRVLHSCLSPDGQMLATAAADESLKFWKVFEKKPASASSSSMSSGKAEMTKSLTIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH46</accession>
    <name>A0ABR3ZH46_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">U3 small nucleolar RNA-associated protein 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_001210</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in nucleolar processing of pre-18S ribosomal RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UTP11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000017">
        <property type="protein sequence ID" value="KAL1899986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007144">
        <property type="entry name" value="SSU_processome_Utp11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12838">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12838:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03998">
        <property type="entry name" value="Utp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="168"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="170"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="274"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="286" mass="32494" checksum="D297709E8766B0C7" modified="2025-10-08" version="1">MSSTMRNAVQRRPHRERAQPLERKKYGLLEKKKDYTLRAKDFNKKKTQLKNLRAKAAERNEDEFYFGMMSRSGPGSRLSRGRSFNGMVDGDRGNKVLDQETTRLLKTQDISYIRSVRTHLAKDVQRLREQIVLAQGISEAGVVAADHQSKTGKVIFAEDEEERAQMLEGLGDDEGDEQKDDDDDFDMAGFNPTNMDDFGGWSSSEDEGDSDNKDKNNDGKKDQKAAEKEMRLRKLNRKLEVMEQKLGAIARAEQLMAEQQAKMAKTATSGGVTKKGKKILVRTRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZID4</accession>
    <name>A0ABR3ZID4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032633">
        <property type="entry name" value="ThiJ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43068">
        <property type="entry name" value="SLR1854 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43068:SF1">
        <property type="entry name" value="SLR1854 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17124">
        <property type="entry name" value="ThiJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="397" mass="44381" checksum="B7D39760A2946469" modified="2025-10-08" version="1">MAQTFPTHSLPPSPMPVLPELEFQDETPFGDFLSPPNYLVSEPPYPYADRYTPSGTRVATPFWTSKAKAPPPAPAAAPTNHNHNHPCWPIADTSTPSKWPIRQPTPYVYSEKSTFAGSSSMLETEKRCGTGMTVTSMSTIDTVTGLQAMAHFGRPVVMDKKAVIIVARSGTNAVDVVTIWSKLRDNGINVFFATPDGDPPNCNMEFLSPWKLYLARMPQYLVDSYNQMLNDINCMVPDSWDYPDFNLFDYDIAFIPGCTGAGFQEMRGNCYLRAALRAFFPLTRRSTKNSSPRILGAIGQGVLVINAATAPLEKVASFHLWWEMLRRGQASQQDLKIEVPLLYHTNAATIPRAADYLGRILGQLKISSHEPDLEWGKSVRHEVRLRLLFQIYGLSYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIG2</accession>
    <name>A0ABR3ZIG2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Amidophosphoribosyltransferase</fullName>
            <shortName evidence="8">ATase</shortName>
            <ecNumber evidence="3 8">2.4.2.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glutamine phosphoribosylpyrophosphate amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ADE4</name>
        <name evidence="10" type="ORF">Cpir12675_001100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + L-glutamine + H2O</text>
            <dbReference type="Rhea" id="RHEA:14905"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58681"/>
            <dbReference type="EC" id="2.4.2.14"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.14" evidence="3 8"/>
    <dbReference type="EMBL" id="JAWDJO010000015">
        <property type="protein sequence ID" value="KAL1900097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004044">
        <property type="term" value="F:amidophosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00715">
        <property type="entry name" value="GPATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01931">
        <property type="entry name" value="PurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005854">
        <property type="entry name" value="PurF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035584">
        <property type="entry name" value="PurF_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01134">
        <property type="entry name" value="purF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11907">
        <property type="entry name" value="AMIDOPHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13522">
        <property type="entry name" value="GATase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000485">
        <property type="entry name" value="Amd_phspho_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4 8 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="9">
        <location>
            <begin position="2"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1900097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="566" mass="61067" checksum="B2BF4FB133230F61" modified="2025-10-08" version="1">MCGVLALILGQTAADPSFPCHAAATLHEALYYLQHRGQDACGIATCSAGGRIYQCKGNGMAAKVFDEGKRVQDLPGFMGIGHLRYPTAGTSASAEAQPFYVNSPYGITLAHNGNLINAPELRRFLDQEAHRHINTDSDSEMMLNIFANELNDTGKARVNQEDIFRALTRMYQKLEGAWACTAMIAGFGILAFRDPHGIRPLVMGSRPSETNPVAKDYMVASESVALRQLGFQNIRDILPGQAVFFGKGSEPVFHQVVPPKAYTPDIFEYVYFARPDTVIDGIGVYASRQRMGIKLANKIKELLGEAGIKEIDAIIPVPETAKVSAASVAESLGITYAEGFVKNRYVFRTFIMPSQATRQKSVRRKLSTVDEEFYGKCVLLVDDSIVRGTTSKEIVAMAREAGARKVIFASCAPPISRPHIYGIDLASPKELVATNKNRFAIAETIGADGVIYQDLQDLCDACAEASPPTGPKQFEVGVFNGKYVTDVPAGYFDRLEEARGELVAEAQAHTLAQATSGSTDGVNACGSATTSEVTVQTPGSLHSEAAGVRDRDDISLFNLATSSSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIZ0</accession>
    <name>A0ABR3ZIZ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="210" mass="24355" checksum="ACCCC446D7AC44C9" modified="2025-10-08" version="1">MADEDEKQQPLVVSRARARAEFMNLPTELHIMISKLLIYPDALSLKHSSSYLYNLIDTGVSVKVEWLILRYSLHLKGPDDKKCDLRSDLQFCRGSIPMLIQHYRNHIECEAHPSIGCMIYNTKECLHRRKLVERVCQWSHGDTLRLIIAISALSMSWSLPLKGFGVDRRVQMSVREWMMPFLATCMAILLADAVQLARSRYRQRRALLQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKE1</accession>
    <name>A0ABR3ZKE1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TauD/TfdA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000559</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050411">
        <property type="entry name" value="AlphaKG_dependent_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696">
        <property type="entry name" value="GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696:SF49">
        <property type="entry name" value="TAUD_TFDA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="2">
        <location>
            <begin position="91"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="391" mass="43592" checksum="DB0BE41904679B7B" modified="2025-10-08" version="1">MLVQSRVYDAMASPANALPFSHYRYIHDTALPLPAGLPTSFKSPKSWTGSDYANDNSYILMLSQNDVKEIDKALAHMNASELPNGIDSISPATFPLPLLGPKLSGLGDELYKGRGFGLIRGLDVNKYTIEDRSAIWLGLQSYVASLRARQDKAGNMMAHIVADNSSVIKAAHHRHSASSIFNLADGQTFHNEESGDIASWLTCSTAASGGRCIIASVETIFNAIAANFPEMIGTLMKDDWPFALPHFQLRPIMYYHNNQLIINFNRTALMGSASHPRSKDLPSLTADQVAALNVIEAFAKANQLEIHTQPGDIHMINNLCLLHRRDAFVDGGDPSTRRHLIRMRLRCHKRGLELPIELQDEWRQAFEDKGDRLWHLMPMPDGFYPLRLYSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKH4</accession>
    <name>A0ABR3ZKH4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Urea active transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_000572</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050277">
        <property type="entry name" value="Sodium:Solute_Symporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48086:SF10">
        <property type="entry name" value="AGR155CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48086">
        <property type="entry name" value="SODIUM/PROLINE SYMPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="380"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="473" mass="50965" checksum="823D218E9E355375" modified="2025-10-08" version="1">MATVAGVQGLVIYAFSCGIPMLVFAYFGSIIRKQCPDGFVLTEWTRQRYGVIASLYLSFMTLFTLFLYMISELSAIGQVINTLTGLKGISAVIVECVVTTIYTSLGGFRISFFTDTIQGVMILCLVFMATISIGTTADIDRSLIDSSGLLDSSLLGWQLLYILPVCVITNNFFLSSYWLRTFASKSDKDLWLGAGIASVVVTCVLVLVGMTGIIAVWAGLYTDDVDADPSAAFFLLLEQLPTWVIGVVLVLSVAMSTAALDSLQSAMVSSASNDFFRNKLNIWYIRAMVVLVMIPIVVVALKTPSVLQIYLISDLLSSAVVPILVLGLFRRFFFLRGFDIVVGGLGGILTVFIFGCIYYGNSQQGADLLLIEQGLTSGDWGVFGAFVAAPFGGIAWGFMAAGLRMGINYILAKRNGTRFTDLDRPVSKALAVVGEPLSSNSPNVAKDSGLTKNMGEIDEHAVAPVNTPAGKFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKI1</accession>
    <name>A0ABR3ZKI1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_000561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1901195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="95" mass="11068" checksum="A796E17F287AD5C2" modified="2025-10-08" version="1">MIARIRKGRKLGSKEEVRILPTDTEWDMIMGTQYYQKMPQVMDKPVQKILLRNQDRTSWPEEDEKEPEFQAAIAVELADRVSVAMGDYGATYARF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKT8</accession>
    <name>A0ABR3ZKT8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_000811</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045517132" evidence="3">
        <location>
            <begin position="21"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="359"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="448" mass="47702" checksum="6F8BDC0E716AFA1D" modified="2025-10-08" version="1">MTPALALAVTAAFGVQAASSLPSAVHHIGIDITLIPDPTATSIPGKPLSDSHISITGPISLSAVDLGISGSRNAYHAAQLNVGDQGIVISFDDSHVGSAAPIRKTISPMLDGLCSASATNAAGNGGDDGPCAKKSSEIEIEAARAVLGAENHPVTVFTLRLSKLDDKQVEPPMYAQFAFDGAKSGSLIFLSDAPPTPKDEDEGSDEDNHNHEYDHNHDQSHGSHRHMHHHGHHHRPPPPGECDELRCRVADFFRAFSPFSAGGPPDTGYEAFDVDSPGPHMHHGPPGEPGIGMRPPGDFHHGHHHGHGAQPDNAGEDGPDDNDGDVPPPPPPPHHHGHHHGHHHHHHGHHHGHGPHPPFALFIINAFFSSIGFVFTMRLAANHFTSYMSKRKNTSTPVLDSNDNAQADHHAVLLSSPSHTAFKETSSLLRNAAPPPVYIEKENIDAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKV1</accession>
    <name>A0ABR3ZKV1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_000685</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat MET30/SCONB/SCON-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22147">
        <property type="entry name" value="F-box_SpPof1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051075">
        <property type="entry name" value="SCF_subunit_WD-repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19872">
        <property type="entry name" value="UBIQUITIN LIGASE SPECIFICITY FACTOR/HREP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19872:SF9">
        <property type="entry name" value="UBIQUITIN-BINDING SDF UBIQUITIN LIGASE COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="3 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="8">
        <location>
            <begin position="344"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="505"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="545"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="624"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="760"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="23"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="82"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="426"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="712"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="82"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="96"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="110"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="158"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="436"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="870" mass="97698" checksum="8FCF0505C2A38BD3" modified="2025-10-08" version="1">MDQPQLSLPAIDAAAPEATSHIATTSPSHTTSPTSVASSTTPATTASSTATKASINLNRSHNKNHHSNDHDRNDLYHHDRQYHDHSHSHTVHDTDNNPASIQSSVTTQRRSIHSHPHSHSHSHSHSHHHYHRHHRRNHNTGFQQHSHDNYSGSAPTSQKDRDIDDYRRSDEADSSRLVQMTTALAGNTVSPFLQDHIPSLYAPVGKPDLSITGFVRKDKDPNSKFCYRHAPGSKCRRAADETKMAMIQNVSKLTRDQKRNISPPPYPFLGLALLVCNSALTFTSTLQELDKLPPNDQQAITHVWSLFSAAPSKHRELMLQGIITQCCFPQLSTVSREVHEQLKIDFISALPPEISYKVLCFLDTVSLCKAAQVNRRWRELADDDHVWHRMCSQHIDRKCTKCGWGLPLLERKRLQEWKPQTNAPVIDVTDEHDGGTENNGITNNDTAGLGAGANKRKRSEADCERRVVQNKKRREEERRLWKDVYRERFEVGSNWKYGRCSIKILRGHQNGVTCLQLDDDILATGSYDSTIKIWNVQTGELIRTLTGHTSGVRTLQFQGAKLISGSLDKTIKVWNWNTGECINTMAPHQDGVIALHFVDNWLASGSIDKTVKLFNFHTRQSWCLRGHTDWVNHVRIDIQSRTIFSSSDDLTIRMWDMDTKECLKTYHGHVGQVQQVLLMPEDFEPDEITSMDDTASVSSSSRDCSPVLMHQHMDSHEPKNNGLDDGQKHGSYSNSSPPPDIRAIFGHCFEEDLARPLPPSYMLSAGLDNTIRLWDVATGRCLRTMFGHVEGIWSLTGDTLRVVTGANDFLVKVWEPRSGKCERTFAGHSGPATCVGLSDSRMASGSEDGEVRLYTFEGNTKALVECGTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLJ8</accession>
    <name>A0ABR3ZLJ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Proline-rich protein LAS17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_000837</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01205">
        <property type="entry name" value="EVH1_WASP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033927">
        <property type="entry name" value="WASPfam_EVH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000697">
        <property type="entry name" value="WH1/EVH1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003124">
        <property type="entry name" value="WH2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00568">
        <property type="entry name" value="WH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00461">
        <property type="entry name" value="WH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50229">
        <property type="entry name" value="WH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51082">
        <property type="entry name" value="WH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WH1" evidence="3">
        <location>
            <begin position="17"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="WH2" evidence="4">
        <location>
            <begin position="615"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="229"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="251"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="269"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="343"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="376"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="444"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="540"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="633"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="667"/>
            <end position="679"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1900703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="699" mass="72138" checksum="D34EE18ABE77D4A5" modified="2025-10-08" version="1">MPTILNDDDKETVRRYVPKQSNKIQAVAVAKLYVAHPSRSHWTDTGIQGAIVLSNDLVGNTFWLKIVDISPSNRGVIWDQEIYESWQYNQDRTFFHTFEMEECVAGLSFVDEKEAKQFLKKMNDREKNASKATKATPFGGSGQPVNQKYGILGGLFGGHRHSSAPTVGAPRHQASSSNGNYSEFALLDTFDPQWRENFGEDLKQMGLTEDLIKEDQEFIVRFLREEQQKQLRASEPAQRHAPPPPPLESAPVSTTSTPSINSNGKSVRQPPPPPPTSRSTEPPAPPPSRRNGAPPPPPTRRSAVGVDISPNRTRFAAPPPFPDAGKYARSSAPPPRESAAPPLANPGPPPPPRPGKVPTDAPAAPPNNRPSVHMMPPAPPAPPARNAVPPPPPPREAVAAPVPPPPPPALPPKIAAPPPPPRVTTPPKAPASAVRPVTHAPVNNAPPPAPPSLPPPSKAPLPTNNAPPAPPPAPPAPPAPPAPPAPPVPFNSAPPAPPMPPPLPSNNAPPAPPLPQSSAPPPPAPPLPPSNAAPSLPSSMAPPAPPPPPPSNAPPLPSGGAPPPPPPPPPPPMPAPSAVGAPPPPPPPPGPPPPATTSRDSGYASGPPPGAAAGGRSDLLAGIQGAGGIGGLRKVDRSKIHDRSGVSIAGNNESSSSPPAAGGGAPGAAPSMADALAAALQKRKGKVSKSDDESDNDDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLU8</accession>
    <name>A0ABR3ZLU8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit H</fullName>
            <shortName evidence="4">eIF3h</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">EIF3H</name>
        <name evidence="7" type="ORF">Cpir12675_000379</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit H family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08065">
        <property type="entry name" value="MPN_eIF3h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03007">
        <property type="entry name" value="eIF3h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027524">
        <property type="entry name" value="eIF3h"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045810">
        <property type="entry name" value="eIF3h_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19445">
        <property type="entry name" value="eIF3h_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MPN" evidence="6">
        <location>
            <begin position="14"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="360" mass="40299" checksum="3C854517C2FA7009" modified="2025-10-08" version="1">MADATKDSAPTVSVQVEALVILKIAKHCSSSFPTTVTGALVGLDTEATLDITNSFPFPSVESNSPEHSDSAQASAAPRQKSIMAYQTDMIRKLKEVNIDANAIGWYTSATMGNFFNLSLIENQYHYQKDNQLAIVLVHDVSRSSQGTLNLRAFRLTPAFMAAYKENKFTTETLQKSKMSFKDMLVEVSIVVHNSHLLTTFLHQIPENIASGDIPKPRSLAEIENGPIKLPPCSSIDNLDLTIDPFLEKTCDLLLESIESHYTDLNNFQFYQRQLAREQAKITQWQTKRKQENATRAMLKQPPLAEDEWQRLFKLPQEPSKLDGMLNAKQVEQYAKQVDGFTANVSAKMFAVRDNLLPKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM43</accession>
    <name>A0ABR3ZM43_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nascent polypeptide-associated complex subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Alpha-NAC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">EGD2</name>
        <name evidence="8" type="ORF">Cpir12675_000598</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NAC-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22054">
        <property type="entry name" value="NAC_NACA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14358">
        <property type="entry name" value="UBA_NAC_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.30">
        <property type="entry name" value="Nascent polypeptide-associated complex domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016641">
        <property type="entry name" value="EGD2/NACA0like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044034">
        <property type="entry name" value="NAC-like_UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038187">
        <property type="entry name" value="NAC_A/B_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002715">
        <property type="entry name" value="Nas_poly-pep-assoc_cplx_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21713">
        <property type="entry name" value="NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01849">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19026">
        <property type="entry name" value="UBA_HYPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015901">
        <property type="entry name" value="NAC_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01407">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51151">
        <property type="entry name" value="NAC_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAC-A/B" evidence="7">
        <location>
            <begin position="48"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="117"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="125"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="159"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="211" mass="23364" checksum="E257E19532EED30D" modified="2025-10-08" version="1">MSDPRVEELPADETKKVVVQEHEDDSSDSEVEAGEGSLPAGAQAVVHSRNEKKARKAIEKLHLIRVPGITRVTLRRPKNVLFVINNPEVYKSPNSNTYIVFGEAKIEDINAAAQQAAASQLAAAAHDDHAGHDHDHDHDHDHDHDHDGEEKKEEAKKEEEEEDEEPADEEGIEAKDIELVMTQASVSRNKAIKALRENDNDIVNSIMALSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMD5</accession>
    <name>A0ABR3ZMD5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcription initiation at TATA-containing promoter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">BDF1</name>
        <name evidence="7" type="ORF">Cpir12675_000319</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05499">
        <property type="entry name" value="Bromo_BDF1_2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050935">
        <property type="entry name" value="Bromo_chromatin_reader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027353">
        <property type="entry name" value="NET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038336">
        <property type="entry name" value="NET_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22880:SF225">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN BET-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22880">
        <property type="entry name" value="FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17035">
        <property type="entry name" value="BET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51525">
        <property type="entry name" value="NET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bromo" evidence="5">
        <location>
            <begin position="284"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="5">
        <location>
            <begin position="481"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="NET" evidence="6">
        <location>
            <begin position="708"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="360"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="665"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="791"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="610"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="37"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="51"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="83"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="132"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="145"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="171"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="361"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="380"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="791"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="810"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="868"/>
            <end position="878"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="878" mass="95240" checksum="E725240590B8E10D" modified="2025-10-08" version="1">MPTPEPQAASLDAKPAESPVKTVSNGDTVKESEKPVSDSQNDASRTQDASVDSKSKSESDQLQKCRASEPLKTDDKIEKPNISSKAASAPAPESAPEKEKLADAEQDVEMTDATPTAEEIQDKKSGSPKATEVSSTSNGISENKVNTKSDSEASEKPKTPDAPQSVDGDTSMADVPSSSSKVSRGRESIEGDEPAAKRTKREPTEEVLPPPVPAPDAATASNANGLKGLNSLERWNDKELEKQAITPYQAREYRRVLAGIKKTKGGGHFKDAVIKLWPTLGEAYLARVTKPMDIGLLERTLRDNPWPNLSGFKDNLSLIYLNTLAFNGELHEVTLAGLGVVEAVWTRCLAISATEPARNKVLPKHMPPRHHEQRHSISHLPPPPAESPAPTPKPKAVTPSARRAASPPESKTTSSDTYAVPPNGVPQIRRASAVTEGDRPKRTIHPPKSKDIDYSSKIGKKKTRPELEFCEEVLGEIRHTRHYAINAAFLEPVDPVALDIPNYFQVVKKPMDLSTIASKLQAGEYQSPKQFISDFDLMFRNCYLFNSPGTPVNVQGKALEKLFRSEWAKKDEWLAKHAAATKAASVSASSVRSDDEFDEPVAPAPAPVVDASLEHEIRALEEKMKEESQRLVDLYMEKHPIESMIELQKNMLNMVQASLLKAKAKQTVTEVKVERPSKPKPKPSRPSKGAAPNPSKKTANSNAGRKPLGGASKKKRNISEAEKGMIATAINELSGNAIENAIEIIKRDTNQTENTNGELELDIDQLSNDALLKLWDLCKKNLPSFAAQISAETTSTTVRDAAPTTNTTGSSAASAASAAARASSKGKKNKPMSAREQEMRIAHLTQVREQFRGTVTGASPEPVSDNALDSEESDSEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMY0</accession>
    <name>A0ABR3ZMY0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methylenetetrahydrofolate dehydrogenase [NAD(+)]</fullName>
            <ecNumber evidence="4">1.5.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mtd1</name>
        <name evidence="4" type="ORF">Cpir12675_000156</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.15" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004487">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01079">
        <property type="entry name" value="NAD_bind_m-THF_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035812">
        <property type="entry name" value="m-THF_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000672">
        <property type="entry name" value="THF_DH/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020631">
        <property type="entry name" value="THF_DH/CycHdrlase_NAD-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48099">
        <property type="entry name" value="C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48099:SF3">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02882">
        <property type="entry name" value="THF_DHG_CYH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00085">
        <property type="entry name" value="THFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic" evidence="2">
        <location>
            <begin position="15"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding" evidence="3">
        <location>
            <begin position="151"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="333" mass="37149" checksum="022A26769C74975C" modified="2025-10-08" version="1">MAEPTAPVACKTILANTIAKGLLGEVHQTLETLSKKPSLVAFLANSDPHAMQYAEWSKKTCEENGFHFELRQVDKEELEEKILEANVDDKVDGIIVYYPIFPGNLMHDKYIQETVALDKDVEGLCHTHLHNMYHNVRFLDAPTNLKKSILPCTPLAVVKIMEFLQLYNPLLAYGNRLYGKTITIINRSEVNGRPLAALLANDGATVYSVDITGVQVFTRGQGIRQVRHQVHDKEGWELKDALPLSDVIIGGVPVESYKIPTDLIREGAVCINFSSFRNFDGPAIKERASIYVPSVGKVTIAMLLRNLVRLITNKADVKRNEEENAEIKNKASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN64</accession>
    <name>A0ABR3ZN64_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="358" mass="39427" checksum="D88BB8EBA764B118" modified="2025-10-08" version="1">MSSRQHPILPPSALEPLTPEELAEMRTSSRHMRQVHAARRQRQRIAASSRVPIDPDEADRPALEFSQSISYLPHHRSYFFGDSGSSCGATACSSAQRRPASSRAAVHFADTTQSRTFAAEATPATLAQTMARREPLHDEPPAASSVHTAHSEALTRANEDRVALEALLHSFAHSPPHESTPNTAEDSGSVWRPPPSPQEDRRTQEPPLEPVISWSDGQIEQVVMSSEGESDKAGSPFREDSNEEGQAIEVESTVVIDVAPATYDKPAMRRNTTAPQGVIAPALAEEQPIVTDSQDQEPVETGANAHFEPTSFIEATGLARDSHTDNGAEIRDGTSRQPRRRRRLARIWMRVQRVFHRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN69</accession>
    <name>A0ABR3ZN69_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sugar phosphate transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_000039</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TPT transporter family. SLC35D subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="163"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="186"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="254"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="311"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="353"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="9">
        <location>
            <begin position="42"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1902140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="380" mass="41709" checksum="FE78A4E4555A60D4" modified="2025-10-08" version="1">MSGDTKERLSVESDVRESTLLPAPATTVKPPATLSDSIPASAYVILWISVSGALIIMNKWILDTLNFRYPILLTTYHLTFATVMTQVMSRTTKLLDGRKKLNMTPDVYLRGILPIGVCFSLSLICGNMTYLYLSVSFIQMLKATTPVVVLLASWAMGNTQPKLSVLLNVSIIVLGVIVASFGEIEFVLTGFIYQILGILFEALRLTMVEKLLSGEYKMDPLVSVYYFAPICALMNFMVALYWEVPRVSYQDFANVGALVFLLNGCVAFTLNLSVVFLIGKTSAVVMTLCGVLKDVLLVASAMIIWNAPVTGLQFFGYGIALTGLVCYKTPYDKLIAQLSDVARFFQSRSTRKLAVVAVSLMFLFYLFSGSPVSAPSPSTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNL8</accession>
    <name>A0ABR3ZNL8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_000120</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="48"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1902015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="432" mass="48560" checksum="3EDB759B5AFCC172" modified="2025-10-08" version="1">MEPRYLGDFGNTTHPIKGSSTIHGNRAWITYTVVALCFSLSILVVICRIWSRYFILRRMGLDDLLAIVSLLAVIGEGVSMLYEAEYGMGRHLATLDSNQMWKFERTFYVTVVLYTAALLFLKLTFLIQYYRVLAVQHMRIWYISSIIIVTMWGVSQLLVSILICVPIQGYWDSSVRARCIPAYPQIYINATGNVITDVMILLLPMPAIWQLNVPKGQKRALLGIFSLGFLTVAISIIRFQYLKRSDDVTWTNVVGSSWSLAEITCALVCACLPTLKPVLSKCLPFLRPRVTSQSSLQPGYSTRRLIKFSRSSPTDITGTTVYGNSIAMDTINTTNSMATTLNQSMKDLHYQPRQAEAENLELDMSANYSEYPWAYIPDQDLGSIGEAQMLRIQHDLGLAPTTKFEVTSPENQGNIPQTGTIRVDTEIMVIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPE2</accession>
    <name>A0ABR3ZPE2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mitochondrial import inner membrane translocase subunit TIM54</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">TIM54</name>
        <name evidence="13" type="ORF">Cpir12675_000143</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TIM54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021056">
        <property type="entry name" value="Mt_import_IM_translocase_Tim54"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11711">
        <property type="entry name" value="Tim54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="222"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="222"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1902037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="443" mass="50411" checksum="CC59285034B35D17" modified="2025-10-08" version="1">MSDKHSAETAKPMAAAEHVATYKKPTGGNPALRMLGIPNLPSKLPSRNWMIFLTLSTALASAIIYDKRETKRATAKWHQVVSELGRQPLANGNELPRRLTIFLAAPPGDGLRSAQDYYLEFIKPVLSDSGLDWEFVQGRQQGDVRAAVAEKIRRRRRESEGIPQEALTTAQRIDAFRREKGLPEYEGIRGDIVVGRHAWKEYVRGTHEGWLGPLECPSHLVVPEKPKLEAENTEANSEKKEKERPPQPPSYNSTSEYPDEDIPRYIPSVFDPAQPVVYPHLLGFSGTFTRLWRYLNRRKLADEVGAQVAAACFAVHRGWALDPAPESSEFAGQSEAQSALAWEEKDWGKWVWEDEKPPTEGEEVPKIKKERVWKHDVVLDPRIIERMRRFELLPEVQQKADLVVVPEEKVEGWTKGSLRQLWRWGVKQVQSQQKKPTVDVDNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQD9</accession>
    <name>A0ABR3ZQD9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">dynamin GTPase</fullName>
            <ecNumber evidence="1">3.6.5.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">msp1</name>
        <name evidence="10" type="ORF">Cpir12675_000236</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.5"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.5" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019762">
        <property type="entry name" value="Dynamin_GTPase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056495">
        <property type="entry name" value="LIS_MGM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF212">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24550">
        <property type="entry name" value="LIS_MGM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00410">
        <property type="entry name" value="G_DYNAMIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="9">
        <location>
            <begin position="268"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="8">
        <location>
            <begin position="834"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="15"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="189"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="933"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="34"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="192"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="945"/>
            <end position="957"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1901729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="957" mass="105300" checksum="3162EAC631AFC43B" modified="2025-10-08" version="1">MSGRLLARGHLPQLGRVPNHTQLSFRSSPSTHISTTPVTTAGPTSSATASQARTYLRLPTAGLLRADAAVRATRKRLWLPGNAFHNAVIVRNASFARFLPKLVVKFVRIPALFGGVAIGAFAWVQYQANQAGAYAMDVFNKTVDGITDVTSNIFVGAQGAANQTMQGWQNTKEKMPEWVTNLMTLHEQIGTGEDGGSGNGNGNGGQNPKQSRVSPAAAAAGGAAAYGFSQDSDPHKPEEAARDDQMMVLTKKMIEIRNILKNVGQSSTLTLPSIVVIGSQSSGKSSVLEALVGHEFLPKGANMVTRRPIELTLVNTPDSHEEYGEFSELGLRKVTDFTSIQRTLTELNMAVPESECVSDDPILLSIYSPNVPDLSLIDLPGYIQVASRNQPLELKQKISELCDKYIQRPNVILAISAADVDLANSAALKASRRVDPRGERTIGVVTKMDLVDAARGASILTDTQYPLRLGYVGVVSKAPTTVGLFVRGSSNLMSAITKNENNFFNSHPTEFGGESGINVGTNTLRKKLMHVLEQTMSSSLQGTSDAIRQELEEATYEFKVQYNDRPLSAESYMAESLDSFKVAFKHFTEEFGRPQMHQLLKNELDQKVLDLLAARYWNKPIPDLSPARPEPDNIADLPRADPDSLYWHRQLDASVSALTKLGVGRLATTVVAHSIQSNIDSLINSSTFVNHPFARQTINEAASTILNERFYSTSDQVENCIKPYKFEIDIENREWNQGRDNAAVLLKNELADCNAALKNMENQVGGRRKLREVMNFVDKARKGDVVVEGDGHSGAGGFSAALLTKGREAIFLRDRSDIIKMRLMAVKSKQCADLTNKYYCPEVFLNATATKLASTAVLFLNVELLSEFYYNFPRELDLRLGRHLSDEDVERFAKEDPKIRKHLDVIRRKEMLELVLEKMVSLKQLDGSRIVDSGTVNGRGGRNSGKKDQERGRWGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YCH3</accession>
    <name>A0ABR3YCH3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">KIP2</name>
        <name evidence="9" type="ORF">Cpir12675_006930</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000432">
        <property type="protein sequence ID" value="KAL1886015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF75">
        <property type="entry name" value="CENTROMERE-ASSOCIATED PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0493">Microtubule</keyword>
    <keyword evidence="4 5 6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="8">
        <location>
            <begin position="206"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="596"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="697"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="836"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="918"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="44"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="141"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="154"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="601"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="611"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="704"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="852"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="285"/>
            <end position="292"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1886015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="966" mass="104110" checksum="B1F9E1D06E80AB8C" modified="2025-10-08" version="1">MTTLPRPARPTLCPPTGSLPAIPMPKTRKSTIGLSSAAAAAASGPTTPRSGLRTPSSSLHSPTRSNSGVNAASKTLRKTVSINSFPQPPRGDNRSNSLPPSPLFASELSKRNSTRKSKTSMGSPLSSSLGFSSTISEGKSIPTTGNRTSDGFISVSSPPHSRTSSAQDSYSTSATTYDDPADISQNTQDTMASVSTGGKKADGKGNVIVSVRVRPTGNSPDRNDGEWLVDGRSSTISYNGKETGDYTYDNVFSTHDNNSRVYDHCAKRLVRRVMEGYHGTVFAYGMTGTGKTFSMQGTASSPGVIPLAITDIFSYIRETPSREFLLRVSYLEIYNERIQDLLSMPTASGPGGAGQQEEIKLREDAKRGVYATPLKEEIVQSPTQLLRVIARGDQARRTASTQFNSRSSRSHAVVQIVVESRERVPGGVETGSKRSGLLPGGVRVSTLSLIDLAGSEKAAESKERRQEGSHINKSLLTLGTVISKLSEQREGKGSDKEGKHLPYRDSKLTRLLQGALSGNSLVSILCTIQTGVANATAHATHITETLNTLKFASRARNSIVSHAKRAEEALGAGGEGGARVLLERYRMEIQELRSQLETQQKNGGKSGSSSDKSELDLQRDAEEERLRELEAESRHEEQILEMQLARTALKERIDHLNKLILSSKSIGVNTSGSYSSLGMRFSTMSQVSIRSSIAPSIASRSMNDRTSSMTSTSTIGRRSSAGGNNRLSGDALPTTEDDESFGEFGDGTASMAAQNRALQADLVDKNRYIATLEKRLIQARRASSSRTSVGLSTPNKGIMVGEDHSVAALLKEKDSEIAELRARLDDKDRMLSALRSATRSREVAESSFEARSPQSERLSGSSNFFSTQAPSPAPTMMIAAPKRLNKTTDDIRILDEMISDRIDSGHIVRNARGSVRVNDRSLRNARSQSSRERALPPSQEPSPTRIVASETLADLPETTKPVAIEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YD60</accession>
    <name>A0ABR3YD60_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cell division cycle protein cdt2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_006890</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat cdt2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000407">
        <property type="protein sequence ID" value="KAL1886049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051865">
        <property type="entry name" value="WD-repeat_CDT2_adapter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22852:SF0">
        <property type="entry name" value="DENTICLELESS PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22852">
        <property type="entry name" value="LETHAL 2 DENTICLELESS PROTEIN RETINOIC ACID-REGULATED NUCLEAR MATRIX-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="87"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="21"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="87"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1886049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="661" mass="73041" checksum="C73243624F03C5DD" modified="2025-10-08" version="1">MAAASPPKQSSARPKKVASVTPKRFARFFTPRTTTRSSRKRNAAEVDEEESIGSRSTKRQLFPAAVQQQISDRPAVVSARDVEWELPSHSRPSTENHTKATIDVNPSLGEDWMPYMSSPYMRHSRPQPSPGRSEGDDAEEHSLGSDQTPTKARPVAATRTIPAVPIKRAENISFRSRLLYKEFGDISKSVWLYVLQVLTIPGNGSMHMAFVGDSNGTVHGLEMHEDGFPQIARFWRAHENAITAIDTKGPYLATASGDRTARVVDFETGKTLVNLDPSNEALRDIRFRPSDPHVLMTSSRGGVINIFDIRHRQPTHALDCAEMTFVEWMPPRPIFPSVQVRHSKPIHTISRAYAFKDHQSNSPQSSITAVRWLPTRDHLIVSAGGSDASLTLWDSRYISRNNVAPLAHTDLPTNDPYYTRNFGVTSLSLSSDGSRIYSTCRNSSIYAYSVPHLILGQAPELGPLDNSRLPHKGLNHRGLGPLFSLRHDDLSIDSFWIKSSIQPSAVTGSGDILAVGNSKLCPVVFNVDEKTIRAQRQCDDTGPRLFASSSYSNTDSSDTPSLPCIMNGVTLYIESQNGLTSNSETTSVAWQANGSLVATNDRGEVRFWHHDTEHPALLRAHDASSPVASYSWANVAQNLCALDSQEYGEMTSPIQLKRVKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YDT8</accession>
    <name>A0ABR3YDT8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADH-dependent flavin oxidoreductase</fullName>
            <ecNumber evidence="3">1.3.1.42</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">OYE32</name>
        <name evidence="3" type="ORF">Cpir12675_006971</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.42" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000464">
        <property type="protein sequence ID" value="KAL1885982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016629">
        <property type="term" value="F:12-oxophytodienoate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02932">
        <property type="entry name" value="OYE_YqiM_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044152">
        <property type="entry name" value="YqjM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43303:SF2">
        <property type="entry name" value="INDOLEAMINE 2,3-DIOXYGENASE PYRROLE 2,3-DIOXYGENASE (AFU_ORTHOLOGUE AFUA_5G01450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43303">
        <property type="entry name" value="NADPH DEHYDROGENASE C23G7.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="2">
        <location>
            <begin position="39"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1885982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="427" mass="46610" checksum="C0E231A39E2B0816" modified="2025-10-08" version="1">MSFPTKTPNTPAKGVPYYTPAQSPPAGSVSEDQANVPTLFKPLAIRDITLHNRIAVSPMCTYSAYDGTATDFHLVHAGQFALHGASLVMVEATAVQPRGRITAECLGLWKDEQIAPLKKITDFIRSQGSVSAIQLAHSGRKGSTLATWVATKRKEVALESEGGWPDDLISASDIPWDEGFPTPRAASEEDLKQLVNDFKSAAVRAVQAGFDIIEIHSAHGYLLCQFLSPVTNQRSDKYGGSYENRTRLLKEVITATRSVIPANMPLFVRISATEWLEHTGQPTWDVASSIRLAKELPALGVDLLDVSSGANSPAQQIPRNQKLYQLDIAGQIRAALHEDGLKLLVGGVGMIRDAEIARVVVQNGTETVAPEYGQTTRADLAFVARQFLKDPAFVLNIARDLGVEAKFPHQYWQVAPKVYREEMGKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YEY9</accession>
    <name>A0ABR3YEY9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006937</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000437">
        <property type="protein sequence ID" value="KAL1886009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185:SF1">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1886009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="183" mass="20439" checksum="773519B06CF1A75F" modified="2025-10-08" version="1">MTKYNVDSLPTIFATYNTPKPFSKCKIWEVARATSAAVNFFDSIRIGRDEIEFIDAGFGYSNPCEVLIKEATSIFPNRTIKVTSIGTGLGDIVGIQDTKESVIEALKKMAESAKDVDLRLKQKYRKTQDQGKQYYRLNVARGLSDIKNWDCSETSKISGHTGNYLAEGEHLVNELADMLGKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFG7</accession>
    <name>A0ABR3YFG7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">5'-deoxynucleotidase</fullName>
            <ecNumber evidence="7">3.1.3.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_006735</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyribonucleoside 5'-phosphate + H2O = a 2'-deoxyribonucleoside + phosphate</text>
            <dbReference type="Rhea" id="RHEA:36167"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18274"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:65317"/>
            <dbReference type="EC" id="3.1.3.89"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the HDDC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.89" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000362">
        <property type="protein sequence ID" value="KAL1887034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039356">
        <property type="entry name" value="YfbR/HDDC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11845">
        <property type="entry name" value="5'-DEOXYNUCLEOTIDASE HDDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11845:SF13">
        <property type="entry name" value="5'-DEOXYNUCLEOTIDASE HDDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13023">
        <property type="entry name" value="HD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD/PDEase" evidence="10">
        <location>
            <begin position="70"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1887034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="238" mass="26885" checksum="BF59019C1D704393" modified="2025-10-08" version="1">MTVHSHSFAELGVVSTATVQGEWTVQAALEESSISNKPVEGSESPVPFIHILERLKTTKREGWRRFGITYCESISDHMYRMAIMAMILPASLAARVDQDKCIKMALIHDMAELLVGDITPVDGVPKLEKSRRESQTMDYLTKTLLGRFDGGLAGKQIREIWQEYEDSKTFESIVVHDLDKLELLHQMVDYEKRANGELDLGEFTYVATKVVTPEINDMAAQVLAERKAFWENKGQPSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFH9</accession>
    <name>A0ABR3YFH9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006732</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000362">
        <property type="protein sequence ID" value="KAL1887031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="430" mass="46432" checksum="EF6FCB0E1D8C7D15" modified="2025-10-08" version="1">MNPDDSTKPKKGLGRALARIKTVLKRGVADKRRSIVVQSDALASPSQPQPPPHTLSSPQPQSDPQPENDLTQEPTAAATAGDDDLHTASSAATPYAIPGPLKPSSPPAPKSAGLPVSRVARSQIYEERAKSIADKFGLNIKSVGEGYMANGEALRVEKPIRMRVHRTCHICSATFGATKECLQCHHIRCRNCVRHPPEHSEVERDANRERIKVIIAERDSGGRNGGVIAVDWNAAAENEAGITSYKNLLLNTPSKVPGAPDLVYKKTRQRVRRTCHECKTQFRPGVKICGGCQHVRCTDCPRDPAKKDKYPFGYPGDVFGPSAIPVHGCHMCRAMFPAGAADGVECARCQHEKCTDCCRLRPCKVEPELDPALVRSVEEKLKALNVSDNKSRGAEDRSATAAAAAAAPSMYGVGSKRPVSASGSELERYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGD4</accession>
    <name>A0ABR3YGD4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphoribosyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000324">
        <property type="protein sequence ID" value="KAL1887395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14681">
        <property type="entry name" value="UPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="130" mass="13992" checksum="8D0B832A5D92697A" modified="2025-10-08" version="1">MDAHIISECSGPLSFGKILIQRNEETALPTHLYSKLPQDLASRTILILEPMLATGGSASQAIDILKQNGALEENIIFVNCIASLKGITVVTSRFPKLTIVTASVDLSMTTSKHISPGLGDFGDRFYGTEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHA2</accession>
    <name>A0ABR3YHA2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006452</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000302">
        <property type="protein sequence ID" value="KAL1887693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="129" mass="13998" checksum="D15895C3DECADE30" modified="2025-10-08" version="1">MAIKNPNFKSKLNRAVYTGTKGRAQRQKSEAQRKSGITKNAIRRGARPGFRPTTGPGKELSKKNQQKRDRALARAAERKMAESGEVEMSDASTVKARTGGRFKTQKAASSATTTAKADEMELDNGANIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHD6</accession>
    <name>A0ABR3YHD6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcription factor SOX-17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SOX17</name>
        <name evidence="5" type="ORF">Cpir12675_006610</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000334">
        <property type="protein sequence ID" value="KAL1887277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01389">
        <property type="entry name" value="HMG-box_ROX1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050140">
        <property type="entry name" value="SRY-related_HMG-box_TF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270:SF161">
        <property type="entry name" value="SEX-DETERMINING REGION Y PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270">
        <property type="entry name" value="SOX TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="HMG box" evidence="4">
        <location>
            <begin position="420"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="420"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="526" mass="58914" checksum="E7D205E0319360BF" modified="2025-10-08" version="1">MHPSFDVNSDAETSQGLEIVNHTDINYSQIGATSQPSPKTNNNVNPPHQFDMNGVSRSNANFERGSASQLDSNINAIISSAPRSNSHEVNAGPRFDLGIEMNTIPQPDVHINIDTNYIPQLVPFEINTVSHFDPNACVSAVFQPDPHADIDMTLVPQLNHFEMGIISPFDPQVGANTLPPFDPYSEITTVTPANLDANFAMDYVPQLNPIEMNNTSSFGPHTGLNGIFQPDPHANINMNYMPSLNHFEMSTIAQSGPIPGMATAAQFQPGIDMRTVSGSNLDVNSDKISNINSNASDSSEIAENQGAILRKIFKMAFQQFSSSSVKLAIIEANLVLSLKPKSKRFLLDSTSLTIGTPAHLVRDLQQPHRFLIGDKILFNTHQKSAVSISGCEDLLWVDIIPRSLTRPAPQAPKKKVEYRVPRPPNAYILYRKDRHREVKAMNPHMDNNDICKLSPAYHYQINADNLLARWLGERWRLETFVIRDHYQKTAADYKEMFMLTYPDYQYRPRKANQRKRRARRTVVSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHP5</accession>
    <name>A0ABR3YHP5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">VLRF1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Cpir12675_006385</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">The VLRF1 domain mediates binding to the 60S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ANKZF1/VMS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000292">
        <property type="protein sequence ID" value="KAL1887860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047139">
        <property type="entry name" value="ANKZ1/VMS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041175">
        <property type="entry name" value="VLRF1/Vms1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16036">
        <property type="entry name" value="ANKYRIN REPEAT AND ZINC FINGER DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16036:SF2">
        <property type="entry name" value="TRNA ENDONUCLEASE ANKZF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18826">
        <property type="entry name" value="bVLRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52044">
        <property type="entry name" value="VLRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 10" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="VLRF1" evidence="12">
        <location>
            <begin position="232"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="281"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="549"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="549"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="603"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1887860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="644" mass="71242" checksum="60566152C2AF1715" modified="2025-10-08" version="1">MSKKTADVFKRPIYLYDIPSYILDSLSAKDAPELQREESELTTVVPAAPSDSPVGSQSCSLCSQSFESMLDQRSHLKSDLHNYNLRQKLRGLVPVTEAEFEKLVGDLDESLSGEDSSDSEDDQQEGSKASTLSALLKRQANLSGFANPGSSNDGDDDDSNSVAKRVEAKTPLTWFESPLLPLNTYFGVYRVMFGPGELSDISKRMEAMRSKQLAPMPAPKLNKDGSPLTAYNGPHIFMLMIGGGHFAAMVVALSPRQIKNNAPGPLNREATVLAHKTFHRYTTRRKQGGSQSANDNAKGAAHSAGSTLRRYNEQALVDDVRALLNEWKPLIDTAKLHFIRATGMTNRRTLFGPYDGQVLQVNDPRIRGFPFNTRRATQNELMRAFIELTRLKVKEILPQEERPEPKASLAPKTITKAPAKPEFNEEEETALLHTSQIQALIRRSKLPALLSYFQMNNIDASFSFFPTDQHHHAPTALHFAATQGSAAIITGLLTRANANPTVPNAEGRTAFELAGDRAARDAFRVARSELGETTWDWAAAKVPAALSKADAEARSERERKEAESKEAERRKTEEARLRRESPVAVTSAVGKDKGLLGSVDAKITPEERREKEARGLTPEMRMRLERERRARAAEARIKARRGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHQ5</accession>
    <name>A0ABR3YHQ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006394</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000293">
        <property type="protein sequence ID" value="KAL1887856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="291"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="325" mass="34897" checksum="4121A7CD600FF63F" modified="2025-10-08" version="1">MPPPSMTSQSMPPQSMPPPSTPLQSMPPPSMTSQSMPPQSMPPHPMTPQSMPPPSMAPQLMTPQSIAPQSMPLQSMPPQPMTPQSMPPPSMISQPMTPQSIASQWAGNQPQNHMVPQWPGGQTQTPVMSQNCMPHVHMNGRIPQGQVFNFAPSPMQRTNFPGNMVMHPNFGPSQIPQPKGSGQINNVGPVMATFQVLPGTGMVNRGVTRTMSQRDDAGDDYQQGATKRHAGSEVGFITPMPPTPTNGHVMPVTDVQRGGRLTETYILTAATQISNQAPIGSQPAPELHGSQYQQQSKLQNQPVSNPSPQSAPRCKPIRPASEKGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIN1</accession>
    <name>A0ABR3YIN1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006406</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000295">
        <property type="protein sequence ID" value="KAL1887820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018830">
        <property type="entry name" value="DUF2434"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10361">
        <property type="entry name" value="DUF2434"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="263"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="345"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="509"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="551"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="572" mass="66132" checksum="07F804C03AB9DABB" modified="2025-10-08" version="1">METIIPLENSIPWPEGDNDTDTVFGGHHLNLTLLRQWNYTLYENHTISNFSKCKMVLEPHFPYAIFTNGSFANSTTCYRALNHIGPRAKTGTGFVALFAICLFFILPCLRKHGRLHLPTERRFFPIGRRWQWYWGSFVCACGIIGMFANIDVDRYYLPSIPIVITSFFWYLAQMGTMALVWEAIRHWNSWSERQWIDPNPFAYPQFDQRGMFEFWLPLVYYLFLWLNFFLVIPQSWGKTQLQRSQQQIDLRAKPFVHAVRFKVGASFLVVCYIINFVSLVHTIWHYKPRGRNWFYQFLNLFRYTPVRFWFILPCQAVMIAFQWAVCFRWDIHPVNIDGDVTAIFTGGYAPMVMIMLIQIIWGLHHANEDLELIRQRRVRGAEADASLGIVYKPNWWRRVHGDDHLNLTMMERLRRRVAAVGGGRRMDAAAAMSDENNGTYQDNIEMSPSGPPNDRPQSKASSGRSKVVLPTPYTGKSEQRRYERTMEIASSMLFPNAPPRITQERLGELQEDGPPPVYRASASGSTSGSGGHESSVRSRSRPRPDSYTSSESADSTTMLNTKPQKIKSMLDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIT5</accession>
    <name>A0ABR3YIT5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Ribonuclease H</fullName>
            <shortName evidence="10">RNase H</shortName>
            <ecNumber evidence="4 10">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Cpir12675_006431</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the RNase H family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="4 10"/>
    <dbReference type="EMBL" id="JAWDJO010000299">
        <property type="protein sequence ID" value="KAL1887743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09280">
        <property type="entry name" value="RNase_HI_eukaryote_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.970.10">
        <property type="entry name" value="Ribonuclease H1, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_bL9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050092">
        <property type="entry name" value="RNase_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017067">
        <property type="entry name" value="RNase_H1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011320">
        <property type="entry name" value="RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037056">
        <property type="entry name" value="RNase_H1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10642">
        <property type="entry name" value="RIBONUCLEASE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10642:SF26">
        <property type="entry name" value="RIBONUCLEASE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01693">
        <property type="entry name" value="Cauli_VI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036852">
        <property type="entry name" value="Ribonuclease_H1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="L9 N-domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="12">
        <location>
            <begin position="207"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR036852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1887743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="363" mass="39656" checksum="D4A52F06DAB9C3D1" modified="2025-10-08" version="1">MITKRKRPSDTSADNTGPIKKRRNNNTQLKFYAVRKGRVPGVYSTWTDCQGQIVGYKGAVFKSFPNLSDAQAFVEGHNPQSYPPKNETPKFYAVARGLQTGIFTDWDETSAAITGSVKPRYKKFPTRAEAVDFIREFGSPEALKAIENEPLVDAVDPKVTIRNSTITPSDVVKPRVILKNSATAAAQKSETSGSTNLLGSGEDDEAYKDFVHVYTDGSSRGNGRVTAAAGVGVFFGYNDPKNVSARLAGEPQTNQRAELTAILFALQRVPHNQKILIITDSQYSIKCATVWAAGWKRKNWMTASGEEVKNQDLVKSITHEISLREQAGGLTSFKWVKGHSDSPGNHAADRLAVNGSNMPKVAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ62</accession>
    <name>A0ABR3YJ62_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1996 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_006209</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000265">
        <property type="protein sequence ID" value="KAL1888353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018535">
        <property type="entry name" value="DUF1996"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662:SF11">
        <property type="entry name" value="WSC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09362">
        <property type="entry name" value="DUF1996"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046503010" description="DUF1996 domain-containing protein" evidence="2">
        <location>
            <begin position="26"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1996" evidence="3">
        <location>
            <begin position="49"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="448"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="391"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="448"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="474"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="540" mass="56851" checksum="9692689CD46BC1A7" modified="2025-10-08" version="1">MKSTKLASSLLALALALFGPSSAVAAPKTSRTFAVMRFNGKEIHNGRVDPIVNPNDFSPHVHTVQGSTGFSPSANGESLRAANCTNSKLKGDMSNYWFPRMYFRDPSSGEIEAVPMFYTNVYYFFEPTDDELTAFPLGLSMLSGNVSLRTPPTSRSGAQVLDPKDGEIQPVGFTCPRNSYSPPSWPADSDGETVGIQDPNNQGQGVGFPNQNCDGYASPMRADIHFPSCYNPEAGVASHKENMAWPTSGNGATAEARTSGRANCAEGWVHVPHLFLEVYWDTASFADRWTPGGNSQPFVLSNGDATGYSLHADFMSGWDETLLQNIIDNCNAGHKGMEYCPGVADQVNTEECSVPPFIDEDVDGPSQSLPGGQDISGWSYGSGSGGGSGSGSKSSAPAVSSSSARQTATYEVYEGKALVSSSSSTPAPVVPAPASSILSPAEYGAPVSVVTSSSSSSSSSSAAPLPLSPPPPALSSSSSSLPPATTPLPAQTTACKTPVVHTVWETVTEFVDADPTAVPVETPSYGRRHLVRHRGRSHRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJI7</accession>
    <name>A0ABR3YJI7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alkyl transferase</fullName>
            <ecNumber evidence="3">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RER2</name>
        <name evidence="5" type="ORF">Cpir12675_006349</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the UPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000285">
        <property type="protein sequence ID" value="KAL1887998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045547">
        <property type="term" value="F:ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="entry name" value="Decaprenyl diphosphate synthase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01139">
        <property type="entry name" value="ISPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018520">
        <property type="entry name" value="UPP_synth-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291:SF43">
        <property type="entry name" value="DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT DHDDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="Undecaprenyl diphosphate synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01066">
        <property type="entry name" value="UPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="219"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="255"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU363018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="357" mass="40606" checksum="BA082FB53E1B6109" modified="2025-10-08" version="1">MSDPYLTHLSRWVRSSPPVEWAVGKVHELIICALRQGPIPQHVAIVMDGNRRYARAQRMETIEGHHHGFEALATTLEILYKIGVKVITVYAFSIENFNRPKYEVDSLMELAKVKMEQLGRHGDVLDRYGAKVCVLGPRNLLRPDVLEVVERTVAMTKDNKMSVLNICFPYTSREEITTAVRSTVQEYLSPQQKSTMFSPSRISQKVLSKHLDSRDVSLPTIRDASPAPSAHSDIDDTASTATTLPPDSPPAVNVRGNNRLPNPETITEDTINSHTYTRENPPLDIFIRTSGVKRLSDFMLWQLHRDTYMAFLSCYWPEFGMGQLLPIILEWQWMQKQKARDERPIKVNRPASGRIAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJL0</accession>
    <name>A0ABR3YJL0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_006322</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000282">
        <property type="protein sequence ID" value="KAL1888052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1888052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="237" mass="27395" checksum="D5C60AB20FFAFC3F" modified="2025-10-08" version="1">MRKVTVEERRLINTSVAPLSARISGSEATPAFGLESIETAGLEHTEEPPVIQTADITIQFYLSDHGYYASSFVNGDTRMYSNHYAEYGTETMLHLYFDEERKVASIRDNNLRYEQDHEDKPPLYKIFKAVSYAQGVNYFAMDWIAMDIDSLDTLNLINDYHERNNLPLEADIRLTQENKYWGSFTDSDYYQQASQMIPWGIDKIIIRRQGRVIEGTDYPTTVAYLILFSFKSSQNFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKH6</accession>
    <name>A0ABR3YKH6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_006088</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000251">
        <property type="protein sequence ID" value="KAL1888659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1888659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="70" mass="8156" checksum="80AE8148CD198836" modified="2025-10-08" version="1">MASEYGRFLYLFIYSRDAFVTSGPEEPWRIEDRYYWSLVTGPSPRDLTRLGRRWIVKKSSALEVTHGAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLP3</accession>
    <name>A0ABR3YLP3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal RNA-processing protein 7 A</fullName>
            <ecNumber evidence="5">2.7.4.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RRP7A</name>
        <name evidence="5" type="ORF">Cpir12675_006029</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRP7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.24" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000243">
        <property type="protein sequence ID" value="KAL1888802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12950">
        <property type="entry name" value="RRP7_Rrp7p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040447">
        <property type="entry name" value="RRM_Rrp7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040446">
        <property type="entry name" value="RRP7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024326">
        <property type="entry name" value="RRP7_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13191">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING PROTEIN 7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13191:SF0">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 7 HOMOLOG A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17799">
        <property type="entry name" value="RRM_Rrp7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12923">
        <property type="entry name" value="RRP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rrp7 RRM-like N-terminal" evidence="4">
        <location>
            <begin position="21"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA-processing protein 7 C-terminal" evidence="3">
        <location>
            <begin position="197"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="87"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="117"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1888802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="318" mass="36626" checksum="5E2F65D020F7F606" modified="2025-10-08" version="1">MAPTSQYQHKAIEGNFIRFLVSMPPMPSFPTSAVHEMRVRRNAPKIPSEKDSRSIFIKNMPVDSNEAYFRALFIQLVGPGCFESISFRDENDPEPEVEPAQAKKIASFNKKRRHNQDEEDTQTAEEEQAKLPQLWTRRIHQSGSAAVVLLADEHNVRIALKKMAKTQSGKNLPVWGDGVSSGTEPLGPIWVMEHLQLCRPDREEMQGSVHAFFNVYNRKEKEAAEMAKRMRNEPDEDGFVTVTRGSRAAPASRSEAEAARKRMMAKEAKKKEEMVGFYRFQMRERRKAEQQALIKRFEGDRKRVEALREKRGKFRPEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLW1</accession>
    <name>A0ABR3YLW1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial distribution and morphology protein 31, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">MDM31</name>
        <name evidence="12" type="ORF">Cpir12675_005832</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the organization of the mitochondrial membranes and the global structure of the mitochondria. Also required for mitochondrial distribution and mobility as well as for the maintenance of mitochondrial DNA nucleoids structures.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MDM31/MDM32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000221">
        <property type="protein sequence ID" value="KAL1889341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012571">
        <property type="entry name" value="Mdm31/Mdm32"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31068">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31068:SF0">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08118">
        <property type="entry name" value="MDM31_MDM32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="152"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="675"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="16"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1889341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="696" mass="77782" checksum="9A42BF33BC0AA2C7" modified="2025-10-08" version="1">MSSRHISVLSAALNRGGSIPLSNAANTGATKALRYSSLPPSRGEDSDSGRSPFKPPHNTTKPTAEKQDESPTYYPSAEPKPGTGTDTIAHQVSKYLHLPNLPTLNNLHAIHRPTKEELLSAANGFWQRLKVRFKWASIRSMRPWNADEWGAFVSWFMLGHIVWILVGTTTFVSIIIWAINTVVAQETLAQWIGDHLTQSAGVTIVFESAIVPKWKDGVISFRNVFVSRRPGQILSSVSKGSSTDAAAVAAAERQPVDSGSTVPITVDDGNYTQYDVTMSTVNVTLSFLKWWNGKGLLKDVEIKGVRGIIDRTFVFWPENLGNPLDYRYEHQPGDFELDSFKMEDFLVTVHHPDGFRPFPVSIYSCELPKLRKNWLCYDFLSANHMSGSFDGSLFTIHPRQVQTYGPAATLGTMGVYMESIGPPEAWKKVSCMRIDGLKIDHLNRGVAGPFGWIYEGNVDIVADIIFPNDEDEGLSKVVSDVYDHLEEIVISNRARFLKEAPEYLDRTGLSAVYKPAFSIHAVPSDAETEAEPETHVSAVPSSYTLPSRTPVFFDDHYHNDHPPPSRVSLANQDDRRYVLFDLRINLNDVKATMPLFTNDMSYVNQALVRPIVAYINAKRTRIPISCRLVKRHCDFCGSLSAWDCGLMDDLSAETYDAFARDVEDQHNRVRRLRKVGFWTLSMAIQALFMGMAGSVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM47</accession>
    <name>A0ABR3YM47_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_005991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000239">
        <property type="protein sequence ID" value="KAL1888928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1888928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="464" mass="49823" checksum="6F82F46A4F9C8601" modified="2025-10-08" version="1">MELGSVLNTETPVTVPDCAQGSQLLDRDSSKRLAICDYSSGLDPECDRSSLQAPGLNAASIVKTATGKAARRRRQSRMMPELTAHLRSAGINRFTAPFQTWIPKGITRNNRRKCTRVLVGSVCAALVSIPDMADFVTATQKAPGKPVQIQLEVDTEFNELCAPLVGEMAMQELHRDVDDQASLSRESDMEPVDCEWVAQPDPVMQVALETGLLCTERALAELPANSVSSAETVSENNVLPVAMRDPRLVTPKQYAAFDNCYYTIQARARFPDWISRSDSDGPRDFLPCPPSPTMSDDSEIIQEVTSLMQSLSLSVGGTSVVPPPWFVASAPPSSLATGPGLAPIFDSTLGPTPLSSPRAHLQSAQEVQAPAPPITGDFVFGVTRSISPIFNPNLGPPSPPLSPLLPPQPSAFPPPQTLFTVPKIVFGVFKAPDIALASNTDIPDFPFTFSSAKPSTVPQFWGAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMJ0</accession>
    <name>A0ABR3YMJ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SWI/SNF chromatin-remodeling complex subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SNF5</name>
        <name evidence="7" type="ORF">Cpir12675_005756</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000214">
        <property type="protein sequence ID" value="KAL1889516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006939">
        <property type="entry name" value="SNF5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10019">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04855">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="428"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="487"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="559"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="688"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="428"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="444"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="493"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="694"/>
            <end position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="711" mass="78991" checksum="2E6360040E1EDE32" modified="2025-10-08" version="1">MSMSTSQSVSNQPSAGPSDSPDAAVSGVASSEPGNEGSSIPVRTKESFQQMMLEQYITRDWLAAINLAEVGKKSQKDTQDAIEEVRDYARIRNDYRAWFTPSRLYGEGYQGYANGFTESMSHSRVIYPSQKPPPGKRITTALKWRRKDMQKQADLHEDLVPIRLEVEWEKIKLRDTFTWNLHDRIITPQLFAAQLVEDMGIKPPATQIVYDMIVSQICEQLEDYYPFAHIKDDSLDPEIPYTALKNDEMRVLIKLNITIGTHTLVDQFEWEMNHPLNSPEEFATNMAQDLALPGEFKTAIAHCIREQTQLFTKSLYTIGHPFDGRPVEDADLVAAFLPSPLNSVLRPQQQAKEFAPYMYEMSEGDLDRNETIFSREQRRQKRSVNRRGGPQLPDLKERQRTIRTLIVSSVIPASAATIEESRLFKRAAGAGRRRGPGAARVDGDLSESDDSEDSAPESPAPANAVVAVTARTRGIRGAASAAQQRMANVGRSETPEHHEPQRVGRRGHRDFMDDDEPQSLIITLRVSPARLRALLNGEQVKITPVPPPIPSLVSASGEPAAMAKPSAPHVPSGQIGRVPAPMPNTDGRPHTPPPAPSWLIRSLTDLAKSYPYDSFEALMKYSAVNPDTEQQIPPGQPPPANAVYMFLPRVRCKDCPGKLYTPGPGQTATNFEVHLKNRQHRDKVDLRIGHPTRSTTPGSGVPTVVPPTSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNA6</accession>
    <name>A0ABR3YNA6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pre-rRNA-processing protein PNO1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PNO1</name>
        <name evidence="10" type="ORF">Cpir12675_005833</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the small ribosomal subunit, ribosomal RNA processing complex (SSU RRP complex).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PNO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000221">
        <property type="protein sequence ID" value="KAL1889342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22391">
        <property type="entry name" value="KH-I_PNO1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22392">
        <property type="entry name" value="KH-I_PNO1_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055212">
        <property type="entry name" value="KH-I_PNO1_first"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055211">
        <property type="entry name" value="KH_PNO1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041174">
        <property type="entry name" value="KRR1-like_KH1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12826">
        <property type="entry name" value="RIBONUCLEASE Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12826:SF13">
        <property type="entry name" value="RNA-BINDING PROTEIN PNO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17903">
        <property type="entry name" value="KH_KRR1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22891">
        <property type="entry name" value="KH_PNO1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="KRR1 small subunit processome component first KH" evidence="8">
        <location>
            <begin position="98"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="PNO1 second type I KH" evidence="9">
        <location>
            <begin position="179"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF22891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1889342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="269" mass="29772" checksum="59BF4F290EB64E7E" modified="2025-10-08" version="1">MSAPTALKPIDTPQAADAAADAAFSVVEGIMQESQNDDDLLLEGASSITPNFEPQNAVAQNDDAEMVLDEDMEGRPRFDAAKDVAAATRIQTRQVRIPPHRLTPLKTNWPRIYPPLVEHLKIQTRFNTKRKAVELRNSKHTTDPGALQKAEDFVKAFSLGFEIEDAIALLRLEDLYIETFEIKDVKTLQGDHLSRAIGRIAGKDGKTKFAIENATRTRIVLADSKIHILGAYKPTQIAKACVCALILGKQPGKVYNNLRGVSARMKERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNV8</accession>
    <name>A0ABR3YNV8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Cpir12675_005699</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000209">
        <property type="protein sequence ID" value="KAL1889619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20335">
        <property type="entry name" value="BRcat_RBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22584">
        <property type="entry name" value="Rcat_RBR_unk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22191">
        <property type="entry name" value="IBR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00647">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="556"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="560"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="786"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="873"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="98"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="112"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="127"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="794"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="873"/>
            <end position="885"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1889619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="940" mass="107326" checksum="5C185B2D63F86644" modified="2025-10-08" version="1">MDGERRTLRGRAVGLPLSVSTSAAAASVATDRNGRHSPLALSDRSAGTPRDHHLRPRLESLNPPPLSAYSRRSTVPATPRPPSVAESRTGPAYSTYGGDRDYDRDDVHFVQSPISVAPPNSSSFAQMERERDSARHSWDATQGPLPTRSRRMSMLQSQGDRSSDRPRRGSLLQNEVPHEKPRRLSMYHPENIPLSGDRHRRGSTMQGDFPPASDRPRRQSFMQQQYQNQQKIQQTKNDMVLASQDLAYSDRFGIPRPSSAAATNSSSGDLVLVKLIDLERDADTVLIKVRPNATLFRVGEALTQCLHLSATDYMVYLYQGVETLRLNQRVNEDSTFYYRLVGPDRNSDSLSEESPKVVFEGRAIRRILQRMGDTTRMLEEHIQRGISVGDFRIVVSKILNLEDPDQVLVEARNGMRVGAIEGEDWRLIDISNFWLCSKFRIFIIQPGRMISIRLLRTTRRFLFHSSPEDDEEFDESDNEEQFCSSLMLKSRFIDRIIVETHATQQSSIIVEPHNLHVYNVSKTLTPQVAWGSLVCVDIPSDVRAQFFAQEEWLLGETTMCDVCLEERHDHEFSSLTAECNHNITMCTLCANKWLDIEMGTHMPNSICCPSCKAVPTLSHLKRWARPDLCERFDMLLTTSALRNITNFYWCINPNCGSGQIHISQCPVMMCDKCKLEQCIMHGTPWHENMTCSEYDNRIGSRKIREERASKATIREVAQKCPVCSSPVELRSGCNHITCSCGIQWCYLCLAVWTKDAISGILHCRHSRDCAEGRNNPMFRPHDDIPARFRHTGDDNNEVFDNDDDDDDDDDFIQGQNQPINERRRRIRAHNIDNGRGYDPGPGLGERGRLNDGAQFPIRERSVMARERIRERDWDRDRDGDRDIGSERTWVPRAHDPATHHPPVTWGNRQPAPQIPHTPRVRTRRESLNPPRRPRLGDYFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP38</accession>
    <name>A0ABR3YP38_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005672</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000207">
        <property type="protein sequence ID" value="KAL1889694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36854">
        <property type="entry name" value="CHROMOSOME 9, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36854:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045520321" evidence="2">
        <location>
            <begin position="21"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="179" mass="19696" checksum="A00E6D7AE3E7B576" modified="2025-10-08" version="1">MAKLHMLILLLGVLVSLAAAQAPVFCKCTCFKNSTIVPLDNISAGSDHGIRSSIYKPPFGFDFISSDDEAITAKAAFDSSPLERRVPPPSCTRCTKAFCLNQGIDFCKTAKEDDVQTMCFQRDSEKDKIIIWAFILGTSGLLGWAAYRKYRETHLKAMGDAMPSRTDYSRIGGLSGERQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPB6</accession>
    <name>A0ABR3YPB6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome c oxidase assembly protein COX16, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Cytochrome c oxidase assembly protein cox16, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">COX16</name>
        <name evidence="12" type="ORF">Cpir12675_005489</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the COX16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000190">
        <property type="protein sequence ID" value="KAL1890196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020164">
        <property type="entry name" value="Cyt_c_Oxase_assmbl_COX16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17130:SF14">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX16 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17130">
        <property type="entry name" value="MITOCHONDRIAL OUTER MEMBRANE PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14138">
        <property type="entry name" value="COX16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1890196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="115" mass="13395" checksum="A3F527017AFA9F56" modified="2025-10-08" version="1">MAFTQKKFRSARDVDTAAGRYRQAIGRHPFLLFGLPFLFVITAGSFVLTRATAVRYERHDRKVRQVLPDKLDNVRKASRKVSWEDEYQKLCADKDLENWSQKRAPRLPGEPDGRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPG4</accession>
    <name>A0ABR3YPG4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TPX2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000205">
        <property type="protein sequence ID" value="KAL1889766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="406"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="516"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="599"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="345"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="412"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="516"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="531"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="638"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="656"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="666"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="752" mass="83218" checksum="21D3F749A15D647B" modified="2025-10-08" version="1">MDSITPNSRDTAPFSVLIEFEDSSSYSPESSRCVSPLSYCSWDSRENNDNGDHRPFESRVDGTLDQDILDGIKNLDIGTSYRSLRNTHSTSHLSAESIVPLSHRLDHRKYILSASSRVSSGSLSCSTVESFEVPRPASPSLLLGLDHHLRHISIGNQGDLPEPSSDIHGQFERHTAGQFQAVLAVPVYDKNSHLDRIADADAVVLKHADDDKLFTLVYGISLLKGLTETQVPGSDQIATKDCRPDAHAGAITYAASGDSKRDSSFANIISVIATRLETHHDILRKHPLIFQRMKEAPSEYPYAQVYPVPIEHEDQPPPYAEAVPSSIFDYKILDQIHPVSQNTTIQTSTMSPSMSPTLQTPTSSHTPRAPSRVEDSVEAIDRLEEDIEALGAQFTHAMTPSQDNTAEMLPQAASSSKSAAKLSPIGARQEHQTLGRSKTVGFQLQRKMRRSSSSSLKKEDEKLPSAESDEKVAKRRSMVARPNSLLPPKPLAKSTRPITTSTFELPGVAVSRRLKEQKEARLAAKQEQDHQSPTQKTPSPRVSTPSLHRVKSTKRLTIPNFELPGEAISRRKRLEHEERLRRQEEKERKAREFKARPIPASIFGGGRYPRETLSSRMRQGKSDGDENCRQAPKRASILTAQGRTTPISSTPGSETPRGRNLEHKSSTGQASRATSTSTIGQISNISVEDINMQRQLGKQIVAQDSLFMRNKEQERKKRLNDLVKPAVNGHKQRQKQVVGASKAMTAAYATTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ13</accession>
    <name>A0ABR3YQ13_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA polymerase epsilon subunit D</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">DNA polymerase II subunit D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_005508</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000191">
        <property type="protein sequence ID" value="KAL1890192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22928">
        <property type="entry name" value="HFD_POLE3_DPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051377">
        <property type="entry name" value="DNA_Pol-Epsilon_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46172">
        <property type="entry name" value="DNA POLYMERASE EPSILON SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46172:SF1">
        <property type="entry name" value="DNA POLYMERASE EPSILON SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="7">
        <location>
            <begin position="90"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="181"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="56"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="195"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="216"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="227"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="293"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="312" mass="33811" checksum="00C5790DEC388FCE" modified="2025-10-08" version="1">MASRKSMETAIRTMAPDVDQTTPPSSPLSSKKTSAKPSRSVESADEAESRNHVNGEDAASAEGGEADANGKPNEDKDGKDIDAIVIEDLTLPKSIMARLAKADLSTGTQIQANAMMAITRSTTVFINHLASAANENTKNSGKKTILPADVFKALDDTEFSFMREQLELEFVKYTEIQAVKRTKKKPASSKKDISDAAANADSASAAVAESDEEDDGPRSKRAKVDESTMDVDEDEDGSVDDEEEQEVQGEDEQGEEEEGEGEGENDEDDEDDEAVVHEEYDATSGVDNDPELVEERLQRELLTHDDDSDDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQM2</accession>
    <name>A0ABR3YQM2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Beta-hexosaminidase</fullName>
            <ecNumber evidence="6">3.2.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NAG1_2</name>
        <name evidence="10" type="ORF">Cpir12675_005688</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the glycosyl hydrolase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000208">
        <property type="protein sequence ID" value="KAL1889684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004563">
        <property type="term" value="F:beta-N-acetylhexosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06562">
        <property type="entry name" value="GH20_HexA_HexB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="entry name" value="Chitobiase/beta-hexosaminidase domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025705">
        <property type="entry name" value="Beta_hexosaminidase_sua/sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015883">
        <property type="entry name" value="Glyco_hydro_20_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029019">
        <property type="entry name" value="HEX_eukaryotic_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600">
        <property type="entry name" value="BETA-HEXOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600:SF58">
        <property type="entry name" value="BETA-HEXOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00728">
        <property type="entry name" value="Glyco_hydro_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14845">
        <property type="entry name" value="Glycohydro_20b2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001093">
        <property type="entry name" value="B-hxosamndse_ab_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00738">
        <property type="entry name" value="GLHYDRLASE20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="beta-N-acetylhexosaminidase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 6 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047054632" description="Beta-hexosaminidase" evidence="7">
        <location>
            <begin position="25"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-hexosaminidase eukaryotic type N-terminal" evidence="9">
        <location>
            <begin position="25"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 20 catalytic" evidence="8">
        <location>
            <begin position="195"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR001093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF14845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1889684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="588" mass="66079" checksum="A7331EA0B9EE1F6A" modified="2025-10-08" version="1">MPSLSRTLAVAASSLLLFCSPAAALWPVPTEVSTGNTTLLISQSLDVTYNGKNVAYTYDCAHPSDVFDDKLLVQAAVSRAMKGIFHDNFVPWKLSPRGKLVQPDVYGSKYDWVRKLCLIQTSNDTSSVLTAPDGEADEAYTLEITETGVATLKAPTLLGLFHGLETFVQLFYKHSSDTYWYTRSAPVSISDSPQYSHRGIMIDGSRNFMPVEDILRTLDAMAWNKLNRLHFHITDSQSWPLELPSMPEVSEKGAYVGYQTYRPADITQIYEYALARGIQVIMEIDMPGHSGSVALSHPELVVAYNEQPYWYYCAEPPCGAFRLNDTGVYKFLDAMWDDILPRINKYTSYFHTGGDEVNANGSMLDPGVRSNDSEVLQPLVQRFVSTAHDQVRKHDLIPLVWEEMVGDWNLTLGSDVIIQSWLGGNATKKYISQGFQVIDSNYEFWYLDCGRGQWLDFDNGRAFETFYPFNDWCTPTNNWRKMYAHDPRAGLSDDDKSLVLGGEVAVWSETIDSTNFDSIVWPRASAMGEVLWSGRVDAAGQNRSQYDASPRLSALRERMVARGVSASPIQMTFCTQADDPLECAYYWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR72</accession>
    <name>A0ABR3YR72_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">MICOS complex subunit MIC12</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Altered inheritance of mitochondria protein 5, mitochondrial</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 11">Found in mitochondrial proteome protein 51</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_005217</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Mitochondrion inner membrane</location>
            <topology evidence="11">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the MICOS complex subunit Mic12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000170">
        <property type="protein sequence ID" value="KAL1890821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031463">
        <property type="entry name" value="Mic12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17050">
        <property type="entry name" value="AIM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1890821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="116" mass="12954" checksum="26085481241FABD1" modified="2025-10-08" version="1">MGFNSGFAGGVTVTLGLVYFSLLTHQRNREYQSLILRSHNAQLASSLDPVPGLVSPSRAEIEAAARANIVDASKDRWNRELQNAARSVQNTDWNEVRERMEISAQQIWVRMIGGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSJ4</accession>
    <name>A0ABR3YSJ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000167">
        <property type="protein sequence ID" value="KAL1890924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185:SF1">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="276" mass="30737" checksum="50C74B7045F2052F" modified="2025-10-08" version="1">MLGRLGMTVDQSIRAYKKFAQTAFTTRRPKFFQKPWPTTFSDINLENAIKQVIHDSCTKAPCVELRQLDSSVYTTCAHEDLLFYDRSCTETAVLALTSVNVEIVPTLLRAYDRSDEFTGCKIWEVAGATSAAASFFSPIQIGRCSVKFIDANFDYNNSCEILIREAKKKSSPGQPMIITSIGTGLGNVVGIRDTTSSVIEALKAMASTSKQATLRLKNEYRNIGGYYRFDVDDGLRDTTVSDWGGMSRISAHTKNYLCKNEHAIREFVQAFTVALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTA4</accession>
    <name>A0ABR3YTA4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Glutathione transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_005096</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000162">
        <property type="protein sequence ID" value="KAL1891127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="205"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="235"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="302"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="366"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="444"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="543"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="570"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="600"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="652"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="724"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="762"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="804"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="76"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1891127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="863" mass="96603" checksum="DC848899E12EA575" modified="2025-10-08" version="1">MESSTPFLSEDDGASYGTVSPPESPPQQKPFTIPPGEQKISHRKPLSRATASSSDGITIDVGGNHYNSGSDDDDSDSHQDAHENSPHESVRAAVPPTDDITLSINTPRMWALSLLFSILGSSTNLFFSLRYPSVAITPVIALLLAHPLGHLWDYVLKRPDDPREHFEAGVLIGRTNVSVRYASFWQRWRLWFGQGWWNEKEHTCVYVSSNVAFGFAFATDVIVEQSKFYKQDVTIPYQLLLTLSTQILGYAFAGLTRRFLVRPSSMIWPGTLMSAAMFSTLHKEENKPANGWRISRWRFFSFVWLGSCAFYFLPGLLFPALSYFNVLTWFAPKNVVVANLFGVVSGLGLFPMTFDWAQITYIGSPLLVPFWAAMNVVAGVAIVMWLLAPIMYYANVLYSSYMPILSASVFDNTGQVYDVGRVLTKDFVFDREAYRNYSRVFLPITYVLSYGVQFAGLAALLTHTACWYGPDIWRTWKKSLQEVSADVSGTTLYQRVDDSSVGILASSRPGTSSGTSIRSTNATSFVREDVHTRLMRRYEDAPMSWYLITFASMTAVGMFVVEYYPVHLPWYGLLMALGTCAIFFIPNGIVMAVTNQHSSIYLICQLICGIVFPGRPVANMVFVTYGYISSAQGIKFAADLKLGHYMKIPPRLLFQVQIAATIVSSCTQIGVLNWMFRNVRGICTPEAVNGFTCPFARVHFNGSILWGVVGPGEFFGQGAMYRPLIWCFLVGGILPIPVWLYARNRKNSIARHINFPVIFGTMSWIPPATGLNFSVWAVVCYVFNYHIRRRAGAWWAKYTMTLSAALDSGLAFGIVVVFFAIIYPNVMGAFSWWGTEVHKQGCDWNACPYKGLPEDGRFGPAEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTW6</accession>
    <name>A0ABR3YTW6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">High-affinity iron permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">FTR1_2</name>
        <name evidence="8" type="ORF">Cpir12675_004806</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000145">
        <property type="protein sequence ID" value="KAL1891801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004923">
        <property type="entry name" value="FTR1/Fip1/EfeU"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31632">
        <property type="entry name" value="IRON TRANSPORTER FTH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31632:SF2">
        <property type="entry name" value="PLASMA MEMBRANE IRON PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03239">
        <property type="entry name" value="FTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0410">Iron transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1891801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="367" mass="40225" checksum="FAD674C54B328695" modified="2025-10-08" version="1">MIFAVQIFFIVFREALEAAIVMSVLLSFLKQCLGQPGQDMVLYKRLVKQVWMGAAIGLGIALAIGAIFIGVFYGVGKDLWAKSEDLWEGVFLLIASIIVSIMGLALLRINKMQEKWKLKIAESMSPATANQGWFKWLGEWGRRNSMLLLPLITVLREGLEGVVFVGGVSLSLPAKSFPLPVITGCISGMLIGYFMYRGGNAMSIQIFLIASTCVLYLIGAGMFSRAVWSFEMYEFARRVGGDVAETGSGPGSYNINTSVWHVNCCSPNTDHGWDIFNALLGWQNSATYGSVISYNLYWAALIVAIIFLMYEERTGSMPLGKQTLNFLGKIPGLRKWADKKKDQSLLSGDAALSQAARQHAGVLQSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVN3</accession>
    <name>A0ABR3YVN3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000131">
        <property type="protein sequence ID" value="KAL1892431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026749">
        <property type="entry name" value="Tmem135"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12459:SF19">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 135 N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12459">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 135-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="613" mass="69637" checksum="4E9A109BD0CC1CAE" modified="2025-10-08" version="1">MPSPPPPHRRSPYTSPTLTHAEAVASLKPPVISPPVPRPASPAQKLQRGSSDPILRNALRYTISAREYSTLHRYLISRSRVLSQTAPTPARVEQIVGSDDAERQKDKMQGKGLLDTNNAEDEAEENDYNARAVRHSMRVFVLTGLASKIWDMVLLKLGKKKDSTTSKKQPLHKSATLQLSVSLSTILLLYRLLFRFLTRLRSHLLDPSAAPFRLRNPRAAAALTSQYAPAVGASFAGLMLGISPARHMRVSVAIYALFRALEFSWNLLEYDGIIWGFKTLTNGFKIKNHRPWWFGSWLTQPLVFGQLFHSLVFDRDCSPLAYTDWIMKQSMTYFQQRPEEYSIGLPWPSAYEIVDSLAGMAKLNWPTYVSPTLFPNKEVLPASLSAISPLTTRAHPLIKSLSCATLHPNDPSCMRTYLTFWLQSFPPIAKTLFAVYSAMSLLPRFRTLTEAPMKLFTDIVLRSLKLSAMATASISSAWASICFFQSWFPRSFMARQRFFLGGFIAGLWSFLERKNGRGAFLSTARLSIDSLWKVGVKRRWWVGMRGGDVWLFVFALMVSSVVYEKDARAVRENNWRKSISWIRGEGFKDWSYQLTEEEERKKEEEEEAKQLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVR3</accession>
    <name>A0ABR3YVR3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Succinyl-CoA:3-ketoacid-coenzyme A transferase</fullName>
            <ecNumber evidence="3">2.8.3.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_004653</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate</text>
            <dbReference type="Rhea" id="RHEA:24564"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:35973"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="2.8.3.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Ketone metabolism; succinyl-CoA degradation; acetoacetyl-CoA from succinyl-CoA: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 3-oxoacid CoA-transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.3.5" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000137">
        <property type="protein sequence ID" value="KAL1892145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1080.10">
        <property type="entry name" value="Glutaconate Coenzyme A-transferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012792">
        <property type="entry name" value="3-oxoacid_CoA-transf_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012791">
        <property type="entry name" value="3-oxoacid_CoA-transf_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014388">
        <property type="entry name" value="3-oxoacid_CoA-transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004165">
        <property type="entry name" value="CoA_trans_fam_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004164">
        <property type="entry name" value="CoA_transf_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02429">
        <property type="entry name" value="pcaI_scoA_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02428">
        <property type="entry name" value="pcaJ_scoB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13707">
        <property type="entry name" value="KETOACID-COENZYME A TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13707:SF23">
        <property type="entry name" value="SUCCINYL-COA:3-KETOACID-COENZYME A TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01144">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000858">
        <property type="entry name" value="SCOT-t"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00882">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01274">
        <property type="entry name" value="COA_TRANSF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="517" mass="55424" checksum="D0F26922B85B0AC3" modified="2025-10-08" version="1">MALRLNRVCVMAALRAGPSFVRCFSVSASRPRINKIVDSHLSAVRDISPSSTVLCGGFGLCGVPNTLIGAIEQTPAIKDLTVVSNNAGTDTDGLSVLIRSRQISKMISSYIGANKTFETAYLTGQIELELNPQGTLAERCAAGARGIPAFYTPAGVGTVVETGELPVTHTADGVPERYSAPKRTETFGGRKYVLEESIFADVALIKAHKADRLGNCTFRLTAQNFNRAMGANARLTIVEAEEIVEPGEISADAVHLAGIYVDRVVQSEGTTNPQEKKIERLTFAREETDATKTNAEPEPESKRDFIARRAAREFQNGMHVNLGIGIPTLAPGYINADTEVRLHSENGIIGFGDFPNRGEQDADLINAAKEIVTLKPGAAVFGSDESFGMIRAGRIDLTMLGAMQVSATGDLANWMVPGKIKGFGGAIDLVSNPNHTRVVVTMEHVDKKGRPKILSQCEFPLTGRQCVKRIITDLAVFDVDHASGLTLVEIAEGVTVKEIQAKTAADFAVAADLKPMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWT6</accession>
    <name>A0ABR3YWT6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004372</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000121">
        <property type="protein sequence ID" value="KAL1892838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="172" mass="18254" checksum="1FAF4B7DC9EE927A" modified="2025-10-08" version="1">MIRTFADHPDTCSDISMPDFDQVPESLRQTNATIELLIPYAPSEPELLACPCDIPSSLSSSKATTIPLKVQPATPTASSRQPSLEPRLSAYESSPLMSTPNITKTAPPASRPSKPCQVPTASQEAGFGFPPLPLPPSPFKSPAASPAPVSHEHNSAVYPSRLAATTIWLVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYS5</accession>
    <name>A0ABR3YYS5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000111">
        <property type="protein sequence ID" value="KAL1893403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="305" mass="33598" checksum="40725AC7FC72A3DF" modified="2025-10-08" version="1">MAPQSNKTSFKSYEVQARLLRAIVAAHQEVKWNYKDKTIREDPAFSHTYGSKAITVHCGQDASICSIRNRFNYLRAQAEIIRLGLDADLDPQHMCIADSSLPRYQTGIDRKNIARHFGESTTDGIQYQFRSIKRDATAMRTAVGNNESPIAAIADSLVATSGNGSSGGARRRVPKAASKAKLEAPNIECDEASDGDEITKRNRDGESDEKDESRLGPLVTSSWLPLKRKRTAGTGVAGEVGFEETPANVQLQQANDSGEHIEPQNQRVVSRSRALAIDLVDYTEDEENDDVDEEEEEGDAVRTDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ85</accession>
    <name>A0ABR3YZ85_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Branched-chain-amino-acid aminotransferase</fullName>
            <ecNumber evidence="8">2.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_004197</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-isoleucine + 2-oxoglutarate = (S)-3-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:18321"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-valine + 2-oxoglutarate = 3-methyl-2-oxobutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24813"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000113">
        <property type="protein sequence ID" value="KAL1893264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01557">
        <property type="entry name" value="BCAT_beta_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018300">
        <property type="entry name" value="Aminotrans_IV_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005786">
        <property type="entry name" value="B_amino_transII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033939">
        <property type="entry name" value="BCAT_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825:SF69">
        <property type="entry name" value="BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825">
        <property type="entry name" value="SUBGROUP IIII AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006468">
        <property type="entry name" value="BCAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00770">
        <property type="entry name" value="AA_TRANSFER_CLASS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 8" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="388" mass="42350" checksum="AF78526F96EC5B9A" modified="2025-10-08" version="1">MSPAATSAGSQAYNELDASKLVITKNTKPSPVPDIEDREAGYGSKCTDHMITATWRSSTGWEAPELKPYGPLPLMPTSSVLHYATECFEGIKAYRGYDGKLRLLRPSKNAERMLMSCLRVSLPGFPPAEFEKLIYALLAIDGPRWLPASESGSFIYLRPTMIGTQQQLGVQTPNEAMLFIIATYLPPMDAPAGGMKLLTSPTDMVRAWVGGFGYAKLGANYGPTLRATSEAKARGFNQILWLYGPEQFCTEAGASNFFVVWRTREGKTQLVTAPLDDKLILAGVTRSAVLGLARERMADDLEVVERKYSISEVMEAHVEGRLLEMFASGTAYFICPISNITHGEYSAVVPVGDDGNSGLVTEGLKSLLRDVVFGKEDHPYAVVVAEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZU2</accession>
    <name>A0ABR3YZU2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mitochondrial distribution and morphology protein 34</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10 13" type="primary">MDM34</name>
        <name evidence="13" type="ORF">Cpir12675_003934</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Mitochondrion outer membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <text evidence="10">The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.</text>
    </comment>
    <comment type="domain">
        <text evidence="10">Lacks alpha-helical transmembrane segments, suggesting that it resides in the membrane via beta-sheet conformations similar to those predicted for other outer membrane proteins and porin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the MDM34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000101">
        <property type="protein sequence ID" value="KAL1893866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21673">
        <property type="entry name" value="SMP_Mdm34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03105">
        <property type="entry name" value="Mdm34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027536">
        <property type="entry name" value="MDM34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058825">
        <property type="entry name" value="MDM34_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28185">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28185:SF1">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26545">
        <property type="entry name" value="Mdm34_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="7" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 10" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SMP-LTD" evidence="12">
        <location>
            <begin position="1"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="356"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="515"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="593"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="356"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="366"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="404"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="515"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="593"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1893866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="620" mass="66156" checksum="E96B599BD7226CF6" modified="2025-10-08" version="1">MAFNFNWSPLTADADFYNRATDLLTTALNKSPKPPIIVDDIFVTELNLGSVPPDLEILEIGDIAEDRFRGIFKMTYSGDAFLTLRTRVQANPLNTYLSSKPSFTSPKPLAAASGLTIPLSITLSEIKLSAFIILVFSRQKGLTLVFRNDPLESLKVSSTFDSIQFVRDYLQRTIEGQLRTLMMDELPAIIHRLSLRLWCKDQLPKEDIVGCSTSQSTASAATSDPTAANFESDPLVEEPAINPLATPPLDPVDSNGNVVDPHEISAFSINDGQPVQSLFSHHSLMCLATLTDSPRTLSLFTPGINDTLYRACHGLRDRPDGTATAATATPSLSKQNSYTGNLTSFAAQSSSVSTTYSFSDSSSATQGYAPSRSSGGLHSPTTGLALGSGRTSRTYQSRKKRNRVVNLRKTPYPDADVSSADGSSSIPDSASSTDKDIPISMSEPMMTSSIAEEPSGPIELDRLMAAVPSASASLLGPSASLSPISTAAATTSPSANASGTSTPLAKVHFDALQNSLANSPTSPNGSKKPAAAPVNPTAFSSLSAALKESERLKAHGGAAITFTSCPPETSSVILEQAWIRKMAGEIARRVYEEKSRRDGFWDDRERASNGEDAPPAYTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZV9</accession>
    <name>A0ABR3YZV9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Scaffold protein Nfu/NifU N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NifU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000100">
        <property type="protein sequence ID" value="KAL1893881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="entry name" value="Fe-S cluster assembly (FSCA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.70">
        <property type="entry name" value="Scaffold protein Nfu/NifU, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014824">
        <property type="entry name" value="Nfu/NifU_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036498">
        <property type="entry name" value="Nfu/NifU_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001075">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11178">
        <property type="entry name" value="IRON-SULFUR CLUSTER SCAFFOLD PROTEIN NFU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11178:SF1">
        <property type="entry name" value="NFU1 IRON-SULFUR CLUSTER SCAFFOLD HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08712">
        <property type="entry name" value="Nfu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01106">
        <property type="entry name" value="NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00932">
        <property type="entry name" value="Nfu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="Fe-S cluster assembly (FSCA) domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110836">
        <property type="entry name" value="Hypothetical protein SAV1430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Scaffold protein Nfu/NifU N-terminal" evidence="2">
        <location>
            <begin position="83"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="312" mass="34350" checksum="EBD4BB13DA0155D1" modified="2025-10-08" version="1">MSLQSLTRAASLLRASSRVTVRSTHTKVSCAAFRSSSASTRYSTAWSPSRPNILSQFNSTAIASSRTGRLSGVLVSGARTIFIQTEPTPNADAIKFVPNHTIIPEKLNRSSIEYLSPRSTISPPYPSPLAAQLMNVDGVDSVFYGQDFITVTKATDANWSFIRPEIFALITEAVTSGQTIVHVADRREGEPAPEEEVDSLAYDESDTEVVGMIKELLESRIRPAIQEDGGDIEFRGFSEGDGMVKLMLKGACRTCDSSTETLKNGIESMLMHYIEEVKGVMQVVDPEEEIAIKEFEKFEEKLKQQQERQATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0C7</accession>
    <name>A0ABR3Z0C7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aldose 1-epimerase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003835</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldose epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000097">
        <property type="protein sequence ID" value="KAL1894100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09019">
        <property type="entry name" value="galactose_mutarotase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018052">
        <property type="entry name" value="Ald1_epimerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047215">
        <property type="entry name" value="Galactose_mutarotase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10091">
        <property type="entry name" value="ALDOSE-1-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10091:SF0">
        <property type="entry name" value="GALACTOSE MUTAROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00545">
        <property type="entry name" value="ALDOSE_1_EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="345" mass="37189" checksum="5D367A87C98F915B" modified="2025-10-08" version="1">MASVSFLPLGAIIQTIKVDGINIVQGFDNPEQYQQHNHPYFGETIGRVANRIKDATITNLNGQSYSLAQNNGPNNLHGGNVGWGKKLWTEIECPIAREVPGIEGLTAAKTTAYGLASKDGDEGFPGTVQATVFYTAGLQKINGRHVTVLAMEYEAELTGGAKETVINMTNHSYFNLNAAPTIEGTRVALATDQYLPVDETGIPTSGPTTFPGIAAGVEFTLDAEDPDIDDCFVIDPTAASTVPIDTRDGPLRLNLAASHPVSGIHLEVLSTEPSFQFYTGKYIDVPAVGGLSKRGRRSGFCCEPGRYVNAVNNKAWKPQVLLKRGQTYGARIVYKAWKEREAVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0I3</accession>
    <name>A0ABR3Z0I3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Dolichyl-phosphate-mannose--protein mannosyltransferase</fullName>
            <ecNumber evidence="4 14">2.4.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">PMT4</name>
        <name evidence="17" type="ORF">Cpir12675_003770</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17377"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:13546"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137321"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 14">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53396"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13547"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137323"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Endoplasmic reticulum membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the glycosyltransferase 39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.109" evidence="4 14"/>
    <dbReference type="EMBL" id="JAWDJO010000095">
        <property type="protein sequence ID" value="KAL1894128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004169">
        <property type="term" value="F:dolichyl-phosphate-mannose-protein mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23285">
        <property type="entry name" value="beta-trefoil_MIR_PMT4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003342">
        <property type="entry name" value="ArnT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036300">
        <property type="entry name" value="MIR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016093">
        <property type="entry name" value="MIR_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027005">
        <property type="entry name" value="PMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032421">
        <property type="entry name" value="PMT_4TMC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050">
        <property type="entry name" value="DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050:SF51">
        <property type="entry name" value="PROTEIN O-MANNOSYL-TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02815">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02366">
        <property type="entry name" value="PMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16192">
        <property type="entry name" value="PMT_4TMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00472">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82109">
        <property type="entry name" value="MIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50919">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 14 17" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="601"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="639"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="726"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="16">
        <location>
            <begin position="334"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="16">
        <location>
            <begin position="402"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00045085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1894128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="775" mass="88749" checksum="7F7E1A797BF7C044" modified="2025-10-08" version="1">MPGPSTPQGTLRHRKGALYEISSDLDPNDEIPDETAKKNNKGSAIKAKCETAHWFTFSIMTLMAFATRFWGISHPDEVVFDEVHFGKFASYYIQGTYFFDVHPPFAKLLFAFVGWMVGYDGSFKFDNIGDSYIANKVPYVAYRGLPAFLGALTVSVVYLIMWESGYSVPACILATALVLLDNAHIGQTRLILLDATLVLAMACSLLFYIKFYKLRHEPFSRKWWKWLALTGFALSCDISTKYVGLFAFITIGSAVAIDLWELLDIKRPGRALAMPVFMKHFAARAVGLIILPFIFYLFWFQVHFAVLSRSGPGDDFMTPEFQETLSDNLMLANAIDIHYQDSITLRHKETKTYLHSHPDLYPLRYDDGRVSSQGQQVTGYPFNDTNNYWQILPSDFNDQSLGRKVKNHDLVRLRHMVTDTILLSHDVASPYYPTNQEFTTVSQADAFGDRVNDTLFEIRIENGKPKQSFKTVASYFKLIHYPSKVAMWTHTKPLPEWAFKQQEINGNKAIAPSSNVWYIEDAPSVTADSERRAKEERKVKHMPFLKKWLELQSSMFYHNNKLTSSHPYASQPYQWPFLLRGVSFWTHNDTRQQIYFVGNTVGWWLASSLMAVYAGIVLADQLSLRRGLDVLDHRTRSRFYNSTGFFFLAWATHYFPFYLMGRQLFLHHYLPAHLASSLVAGSLLEFVFVSETPSDIEISKSKKGKIETEQKHHLTASERFAGQSMISMWIACSILVALLGACWYFWLPLTIGYPGLSVEEIQARKFLGYDLHFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1H6</accession>
    <name>A0ABR3Z1H6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Copper acquisition factor BIM1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_003652</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000090">
        <property type="protein sequence ID" value="KAL1894475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21176">
        <property type="entry name" value="LPMO_auxiliary-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046936">
        <property type="entry name" value="BIM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046530">
        <property type="entry name" value="BIM1-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992:SF10">
        <property type="entry name" value="COPPER ACQUISITION FACTOR BIM1-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992">
        <property type="entry name" value="HYPHAL ANASTAMOSIS-7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20238">
        <property type="entry name" value="BIM1-like_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045123553" description="Copper acquisition factor BIM1-like domain-containing protein" evidence="8">
        <location>
            <begin position="18"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Copper acquisition factor BIM1-like" evidence="9">
        <location>
            <begin position="17"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF20238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1894475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="233" mass="24904" checksum="BCE187759DB3E854" modified="2025-10-08" version="1">MLWFFVFTLAAASLSTAHIVLSYPGTRGNNLITNDSFPYGMQWMYPCGGLGTTTNRTYWPTTGGAVAFQPGWFQGHQLANIHINLGLGTDGPDAGPHNMSFNMIRDVQLVGPSNTPYPGTVCFPQVPMPINITVKAGDKATIQVVEQAQHGAALYACVDIEFAEPGDSKIARVNESNCFNSTEFGFADVYTVTVSEAPSRSSSQASSAQAMGTAVPRNLWLAMALGSLFALLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z275</accession>
    <name>A0ABR3Z275_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Translation machinery-associated protein 22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">TMA22</name>
        <name evidence="7" type="ORF">Cpir12675_004044</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2 4">Interacts with the 40S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="4">The SUI1 domain may be involved in RNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the DENR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000107">
        <property type="protein sequence ID" value="KAL1893614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11607">
        <property type="entry name" value="DENR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.780.10">
        <property type="entry name" value="SUI1-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050318">
        <property type="entry name" value="DENR/SUI1_TIF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046447">
        <property type="entry name" value="DENR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005873">
        <property type="entry name" value="DENR_eukaryotes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048517">
        <property type="entry name" value="DENR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001950">
        <property type="entry name" value="SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036877">
        <property type="entry name" value="SUI1_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01159">
        <property type="entry name" value="DRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12789:SF0">
        <property type="entry name" value="DENSITY-REGULATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12789">
        <property type="entry name" value="DENSITY-REGULATED PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21023">
        <property type="entry name" value="DENR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01253">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55159">
        <property type="entry name" value="eIF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50296">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="SUI1" evidence="6">
        <location>
            <begin position="101"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="68"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1893614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="192" mass="21068" checksum="18ED861E95099A25" modified="2025-10-08" version="1">MADVDEVPAELRGLSVKYCGVCSLPPEYCEYGGRVKKCQEWLETNEPELYNKLWSPEALEAATASLSVDAQKRAAKDAQKKAAKAEAQEAKEAEKVAHSTVVIKRIMRNKNKFVTSVAGLEAFGLDLKKVAKEFGKKFATGSSVTRTAGGIEEIVVQGDVSPEIEELLIANYKNIPKNHIELVEDKKKKKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2U1</accession>
    <name>A0ABR3Z2U1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_003633</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000089">
        <property type="protein sequence ID" value="KAL1894507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1894507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="502" mass="54668" checksum="F7D82405825AD2AF" modified="2025-10-08" version="1">MTRAHRAIGLSRHFSYLSTHAAKAPDASSTSTLPPTSVPGTPLTGPTHHEAYIPSTFETLPNFDATSKTISTSAGALPASPIMDPEWRMTQGFFRASKPRRRPPVGRFRKLFSRSPYARMLASPLRVDPLTDAFLPREFLASFEVVCHPETSSPWWAPLIEDAPPPVRADVGEKGKIEGEGEREDIMGMEPEEDIHEEAEAMATTVAAESTAQSFSLDVPLPDPVEASSSDPAYIATPRLAGASQQPPPVTSTNATAPQIKTLSNLRAYTILSSRILSTLDTRLGGSPKGFPFLATRRSNHMPWIQRSPPVWHHNMTGVMLAMLRARALDDFALLADPASLGKKYPKTAAAATQTDTGSLAEKDDPASPLLCPAYGTEWLSPLVRVESWAELLTAVPDKTLRGAVLWLPASADAVVPADVAPDRQTYTFAGVQYNAHVPIHNLTRLLGEEGVLKVRGMFPEMRDAELVLLVRPSSIHLRTRLWQLEGYLSETGPTPKEQLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3D8</accession>
    <name>A0ABR3Z3D8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Glucanase</fullName>
            <ecNumber evidence="11">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">CBH1</name>
        <name evidence="15" type="ORF">Cpir12675_003398</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains.</text>
            <dbReference type="EC" id="3.2.1.91"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the glycosyl hydrolase 7 (cellulase C) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="11"/>
    <dbReference type="EMBL" id="JAWDJO010000079">
        <property type="protein sequence ID" value="KAL1895126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07999">
        <property type="entry name" value="GH7_CBH_EG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.100.10">
        <property type="entry name" value="Glycoside hydrolase, family 7, domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001722">
        <property type="entry name" value="Glyco_hydro_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037019">
        <property type="entry name" value="Glyco_hydro_7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753">
        <property type="entry name" value="1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753:SF2">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00840">
        <property type="entry name" value="Glyco_hydro_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00734">
        <property type="entry name" value="GLHYDRLASE7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 11" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046303043" description="Glucanase" evidence="13">
        <location>
            <begin position="19"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="14">
        <location>
            <begin position="481"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="408"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="435"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1895126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="517" mass="54242" checksum="3A8A1B342A3143A9" modified="2025-10-08" version="1">MYGQKLSVLATLVAAARAQQACSLTAETHPSMNWQQCSSAGCDTVKGAITVDANWRWTHEVSSSTNCFTGNTWSSTCTNGTTCAEKCCVDGADYSGTYGAVTTDDSLSLSFVTKDSYSTNVGSRMYMMADENKYQMFQLLGKEFTFDVDVSDLACGLNGALYFVSMDEDGGMSKYPGNKAGAKYGTGYCDSQCPRDIKFIGGAANSDEWTPSSTDANSGIGGMGSCCSEMDIWEANKMATAYTPHPCNTIGQETCQGDACGGTYSSQRYGDNCDPDGCDFNSYRMGDTEFFGAGKKIDSTKKVTVVTQFIKGSDGKLADIKRFYVQDGVTFENSESKISGVSGNSINEEFCSAQKKAFGDKDSFTSSGGLAQMGAALEQGMVLVMSLWDDNYASMLWLDSTYPVDSTAAGSARGECSTSSGKPSDIRASDPNGKVAAAAVTPEAEAPAAPVNQKASSTKASTPAGSASTPTSNPGPGSASDAIPRYGKCGGGDYSGSGNCVQGTTCKVMNPYYSQCM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3F8</accession>
    <name>A0ABR3Z3F8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphotransferase</fullName>
            <ecNumber evidence="6">2.7.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_003346</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the hexokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000077">
        <property type="protein sequence ID" value="KAL1895163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.367.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001312">
        <property type="entry name" value="Hexokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022673">
        <property type="entry name" value="Hexokinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022672">
        <property type="entry name" value="Hexokinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443:SF30">
        <property type="entry name" value="GLUCOKINASE-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443">
        <property type="entry name" value="HEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00349">
        <property type="entry name" value="Hexokinase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03727">
        <property type="entry name" value="Hexokinase_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00475">
        <property type="entry name" value="HEXOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51748">
        <property type="entry name" value="HEXOKINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="4 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hexokinase N-terminal" evidence="8">
        <location>
            <begin position="13"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Hexokinase C-terminal" evidence="9">
        <location>
            <begin position="224"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="Hexokinase C-terminal" evidence="9">
        <location>
            <begin position="509"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="486"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1895163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="588" mass="63506" checksum="4C7A9AAB27572DE4" modified="2025-10-08" version="1">MADAKESELHKRAQQIASEFDLDATQVNLAVSYLVQHLNSALSHESTTQIPSFITSLPNGTEKGVFLGVDLGGTNCRVCSVQLQGDSTYTLLQTTSEIPRVVMTENSYMPLFLFVAKCIADFLVENPHLTKPMEEQGPTPVLPLPLGFIFSFTFEQHSLARGVLLQWDKGWAIPTAIGCDPCQMLQEAVDTLKLPVSVCALANDSVGTLLARAYTNPTSPPTLMGAIFGTGTNAAYVEQQRKIHKLASRKASDLDASCGVMLMNTEWGGCFDDNTAALPSTQYDQILDRESKNPGQQTLEKHVSGLYLGELLRLVLLDLVNSNLLRFEIRDSETCPLLKQYHIDSELLSVLAGDRSPDLLMSRQAVAERLQISDITLEDAKGMRTIAMAIGRRAGRTAGVAVAGIIIQSGRVSKFDAKAAPFTAESKIKASEGLLVETKETNAIGCGSAFRPVYHLIKRFLKNKPASPPSHPTIPSSELTFKAQTTSPVSSPTLSNTKTVTSSHCGSETDTGTIDIGVDGSLIEYYPSFEADLRSALRDVVQISEVGEQRVKMGVAKNGSSIGAAIAALYQSEELADKSLIKSDTTTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3K8</accession>
    <name>A0ABR3Z3K8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_003504</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000084">
        <property type="protein sequence ID" value="KAL1894809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004776">
        <property type="entry name" value="Mem_transp_PIN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31794">
        <property type="entry name" value="AUXIN EFFLUX TRANSPORTER FAMILY PROTEIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31794:SF2">
        <property type="entry name" value="AUXIN EFFLUX TRANSPORTER FAMILY PROTEIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03547">
        <property type="entry name" value="Mem_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045359635" description="Transporter" evidence="7">
        <location>
            <begin position="24"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="370"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="403"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="445"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="481"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="520"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="219"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1894809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="545" mass="59998" checksum="69E4640D9336DFC7" modified="2025-10-08" version="1">MVLGFSSALVSRLVLVPLNLAEASGSHESHPDFMHLVVLVMSAVLEVVCVSLPGYIIARMGHFDAEQQKFLANLNMMLFTPCLIFTKLASQLNAEKLLDLSIIPIIFCIMTFVSWTTSRIVAKVFGFNSRASNFVTAMGVFGNSNSLPISLILSLSQTLKGLHWDRIPGDNDDEVGARGILYLLIFQQLGQLVRWSWGYHILLAPKSKYPEYQNEFLEEGRTSGAPTEIGYSNSTDDLSSYDPPGRTPIASSSRASRASPEHSDDEDDLDSTHFAIYKRSNDSQRPLLAPDDEISPRPSFDGHAIAFRSYSYQQQQQQQSNLLSRVGQFFTAPISYLYNSMPIIIQSALSGLKSVLLRFLLGVWDFMNPPLWAMLFAIIVASVPSLQKLFFEEGSFVSNSVSSAIKSTGGVAVPLILVILGANLARNTQNTTNVDPEEEEFGGKLLVACLISRMLLPTVVMAPILAMIAKFVPISILDDPIFIIVCFLLTGAPSALQLAQICQINNVYEGVMSKVLFQSYVVWILPSTLVLVMCALEVVEWASMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3L4</accession>
    <name>A0ABR3Z3L4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ER membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003466</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000083">
        <property type="protein sequence ID" value="KAL1894821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013635">
        <property type="entry name" value="Ice2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31726">
        <property type="entry name" value="PROTEIN ICE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31726:SF2">
        <property type="entry name" value="PROTEIN ICE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08426">
        <property type="entry name" value="ICE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047364982" description="ER membrane protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="279"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="356"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="397"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="427" mass="47450" checksum="19700CA3F72F7226" modified="2025-10-08" version="1">MLWFFRIVFSALFLLSIVLSIPIAFDVGGKDSGLAYSLALFSFYFFYSVFRLITPPESRVRWTITNAICLSQWLAIPSLLIWALSTFAVDVGSAFLTDRNLAWGEADTWSVYVFGQGGLVETVALGGWDTMLRYSSPVFQLLEGFCSLLVIQTAGQMTRWLVNRGRSDTWMIVLLVISGSILGSSGYFLWRVVNFPQITTVDASFIGVTMTTAIFLGGYGITSGKGNVVEASLLFAYVVLCIYQIFTDYLPSHEVFVEHPLQPEFPPLPPIIMASYSTFLHIIGSLPAAVHSFFALLYAAFQTITPSVVISLTYRTIIFYCATRIIPAFRESGSRAMLDEDSFEDTADGANRALGFLSWFSPSFLIAIYTSLLLQHFSASDDSDGWTLRAGDAEGSVWRWVNVIAVISLYSFELYLGGESLSHWKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3Y0</accession>
    <name>A0ABR3Z3Y0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_003436</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000081">
        <property type="protein sequence ID" value="KAL1894977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF7">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00755">
        <property type="entry name" value="AFLATOXINBRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="88"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="155"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="192"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="798"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="198"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="222"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1894977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="929" mass="102406" checksum="BA590E023F759C42" modified="2025-10-08" version="1">MDNREQQKHYHHQQHPPPSSQHNSFNDFPNPLPAIAISAPAPASVLVSTSTPTPSSEQSFSAIAATTGLSSSAPGPKKRRSQASLADCCKTCRLRKVKCTGKPADGVRCTICQRLDLKCSFVALTEGPIDIGSARSTPSRSHTEAGTIRKRAQRACTNCHMHKTKCSSDQPRCKRCEANNMVCEYQVSKRKFNSNDPTTAASVASAASAPSQTSEVSPIDDQPTRVVDDRVPDNAGVDGPAGPGSPEQSSEALHTRFVELLNLESEDLLRRRDFIQLHVDAYFQNVYHLPCLSFYHRESLYKEIEKGTLSPTQVAAICSVAAFFITSNENAKDFAMTCCRQVEFQLFRNVGSLTESNLTLYALCIVHNLFVGKYAKCWQLVAVACRIMLGLQLNWDIPGSQKSFIQQECSRRLAWHMFHMDRICAGGFDAYVCFNEDNMKLRLPCNEEAFQTNQPVSAERLTEKGPRNVSSSTYSMGRQGYTIRLINLRHHVQSIAKKFSGGTAFVHGVKWEASRVMEEVNRLQNEVSSFTASLPDDLKLNEQNIARWAGSREEQIYVFVHSWICALHVELYQFAVPGLQESGSAELLRKLPNTFLIKAQKQAVAFAVAAARFWHMFQAQATINRDPLAPLFLGDTYLMPSVQGCTKVLITALHHNLYDNLAEHSTAPLSRAEPINADSMRDFITATVTFIKPLASVIPSMKTQFTQLCKDVAELDKKLGPKLLLKQAAPDQPLVSPQDPPPATFNVPMKLPGPEFILDNASTFNVSIRADDLSTRPMADPNLMVTNWLGMSTPTPCGSNSGNANPNNNSNGNANGNANAMISSSNTTTAINDPHDMYTDMVGFGPDFDSEFCPPGMPLLLAEARGLPAYSVFPIQHSQHSTRTNRNRNRNCNCNSNINTIQINRGKTNNTTQPFLAKDTTAVYTTQGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4F9</accession>
    <name>A0ABR3Z4F9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000077">
        <property type="protein sequence ID" value="KAL1895157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF31">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN YCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="285"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="532" mass="58320" checksum="1ECE2BFC88B9B25C" modified="2025-10-08" version="1">MALGLLFVYMAPKPTLPIAQFHEWYNNEHGPTRLRLPAIFTNGLRYVGNDGLDPPFLAIYDVTSMHWMREPVYTNLRANRSPREAATIGQVTVDRRFYDLVATHAKQGFAPAEQMPSGGALGRILVVEEVEVGGGTSDAAVNNYIQAFSDVRGPLLAKDVSWLRSRLFRTSTVQDEGDSAQDNRFAVLHEYESTNFNPATEAAKGDGIVAASMRTMKLFYVFGPAPRDLDHLAALPSDSPEFVSADGKSLVTVPGPSGNLQSTVIAPDGLVIPLQLEGNPSPDAPTVAFCNSLLTSLHMWDDFVEILKKERPDLRILRYNHRGRGELPAEVPVSADQLADDLASVLDALRIEKLHVLIGVSLGGVTTLNFAIRHPRRLAKYIACDFNVCGSASNTAAWKERTAIAEADGGNGIKHELAPATVQRWFHPVSMEKTAVVNKMTQMVGQNNLTGFRYGCQALWEYDLRPKMGSCKVPALFIAGDGDAGGKFLTIMKAYEKQIGFDKAEFRSVANTGHLPMTEDAVAFWEVIKDFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4I2</accession>
    <name>A0ABR3Z4I2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_003176</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000071">
        <property type="protein sequence ID" value="KAL1895538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1895538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="80" mass="9177" checksum="C3676046666B843F" modified="2025-10-08" version="1">MSPAGLELLGHGINPDEQDEFTSYRSVTIEFENETNQLQFTEQWNGLLKARRAQREEIDQIQSRMARQGLGARGALKIRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4K1</accession>
    <name>A0ABR3Z4K1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_003434</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000081">
        <property type="protein sequence ID" value="KAL1894975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1894975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="217" mass="24465" checksum="4571B45C22646A2C" modified="2025-10-08" version="1">MYSLLRSIEAQECAFEEHRGVATRFMILLMKEIETQCAREGIQKTAQSMGKEFLKTAEQVMEAILVGRTGNISETHQDGQGQPKQVSKEACTHEKSGTKSLSFTDIARKTAKKLTNTQSSTIILKTHKTAKRGGEWQTITRRKADKFAQAAARQDNRVLVIINKDRKIRDCESFLMAGKLKELNTELRKALKNVQKIRSSFALTAHKNGRATLLEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z517</accession>
    <name>A0ABR3Z517_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Flocculation suppression protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SFL1</name>
        <name evidence="7" type="ORF">Cpir12675_003338</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000077">
        <property type="protein sequence ID" value="KAL1895155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF396">
        <property type="entry name" value="FLOCCULATION SUPPRESSION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00434">
        <property type="entry name" value="HSF_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="6">
        <location>
            <begin position="195"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="377"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="497"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="86"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="461"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="508"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="544"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="554"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="580"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="613"/>
            <end position="623"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="660" mass="71768" checksum="7B56587E76F2E032" modified="2025-10-08" version="1">MATVTENPHRFNMAIPEGRDDHSSRVVPIPTPTIRMSAPPPGDPMDISTSPTRSAPRNGSLAPILKIDEAPNDNVRNGGSPMDGVSSTNNQSQSSANNTSNGNTNNNSNNGTTSSNNIASTNGNGNSSSSNPSNSNMPAPPNAGAAAHQPKIVQTAFIHKLYNMLEDNSIQHLISWSSSADSFVMSPSADFSKVLSQYFKHTNISSFVRQLNMYGFHKVSDVFHTSNPESALWEFKHGGGNFKRGDLVGLREIKRRASRHALVHRELGTQKNQLPPPPGMSEPMPMPDMTDPRVLDHALYDLNMRLQRSEEISHFMQMRQQALTDSMLRMLQFSQDMARAVSTMVPPENPVHREVLGLQGEMARQMEALRPVEEAVQLHPPPHDPYGRGPYYENGPISPHHPPQDDPRRATLVVPPQQPPMPRSGPYYRPAVPSNLSINSNRRPYGSIGGSPQTSPNSRHPGPPPPPPPPPHPLSNVEAAGLGVGRRHTTADIRAHGWQTNVPPPYPSHVGAPAAPAPSSSHQSSSHQQQQAGPPQWPPSPSRPTHDEQKIRDSLSSFSMQGFNSSSAPRSRPATPPPSASFLSGNGSSNNGGNPSQNGVMFSEPSWGGPDNKNLSVRESSVPPTRRGSMAHILNPTMESSERDDDDLRGDDDRKRKRIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5A2</accession>
    <name>A0ABR3Z5A2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glycosyl hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_003032</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000066">
        <property type="protein sequence ID" value="KAL1895810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041036">
        <property type="entry name" value="GH5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052066">
        <property type="entry name" value="Glycosphingolipid_Hydrolases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31308">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31308:SF5">
        <property type="entry name" value="ERGOSTERYL-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18564">
        <property type="entry name" value="Glyco_hydro_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="5">
        <location>
            <begin position="71"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5 C-terminal" evidence="6">
        <location>
            <begin position="667"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="585"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="732"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="585"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="603"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="743"/>
            <end position="753"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="817" mass="91498" checksum="AEE7AC4034D541E9" modified="2025-10-08" version="1">MSQFRLTIEDGQFRDGYGRQVVLRGINCAGDAKLPSTPKQTSYDGEDFFDGDNVKFHQRPFPLSDAHEHLGRIRRHGYNTLRYVFTWEAIEAAGPGIYDEQWIQHTIEILRVAKQYGFFIFMDPHQDVWARFCGGSGAPLWTIYACGLNPKSFAATEAAIVQNVYPDPDEFPKMIWSTNYWRLAAATIFTLFFAGRDFAPKCIINGVNIQDFLQGHFIAAVSHLNRRIREAGDLHNVCVVGWESMNEPNRGLVGYQDICVIPKEHPLKKGTCPTIWQSILTGSGRSCEVDVWAMGGMGPYKTGTRLVDPQGEKAWLPVGYDESRYKYTRDPGWKLGECLWAQHGVWDPETDTVLRKDYFSKSPRTGKRIDHPEFTDTYFMDFWRLYKAAVRREHPDCIVLMQFPTLELPPRIKGTADEDPKMGFTPHFYDGITLMTKKWNRTWNLDVVGFLRGRYLHPAFALRIGEKAIRNCFRDQLACLRQEGIDRMGNHPCVLSEFGIPYDMDEKHAYKTGDYSSQLAALDANYYGVESSLLEGHCLWVYTAISDHARGDQWNGEDLSIFSLDDKPLPVSSIPRSSLALGSNLSLTKGNDDATASESEDGASAPATSLLASSSRRPTADEARVTPTNLGRSMASPPPMSSSASSQGQDPTLTNAPGYRAAEAFLRPTPMYVVGNILQYGFDLRSCTFKLKLKTPAAARAEAPTIIFLPEFHFPRDSYVVEVSSGKWQVSVDDGEGDECEQNSGSKNGSSSSQTIGEGGALLQKLRWWHQGGEQSIKITGLVRKFENLDNASEDTGYMEQCQNSYNFGAMSACTLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5S1</accession>
    <name>A0ABR3Z5S1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">tRNA(m1A58)-methyltransferase subunit TRM6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">TRM6</name>
        <name evidence="7" type="ORF">Cpir12675_003336</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRM6/GCD10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000077">
        <property type="protein sequence ID" value="KAL1895153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017423">
        <property type="entry name" value="TRM6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12945">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12945:SF0">
        <property type="entry name" value="TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT TRM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04189">
        <property type="entry name" value="Gcd10p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="620" mass="68956" checksum="4F803C4D5C71CCAA" modified="2025-10-08" version="1">MGTVVQPNQWIALCVPSGNLRVMQATPNTTISLGKYGTFPSNLIIYRPFHLTYEVQDKLDNEDFCRLRVVSAAELQADIVAEENGMEDLDLLDTNPNAIRIGGGEELSLVDTESGVEVARSNMEILDDSAAQTLSMEEIEVLKKDGKEAGRDLIKKLMLSHMAIDKKTQFSLEKYKLLKTKKYIRRFQVLPLDTPQLAQFLLEEKRDASKILELRQEILALLGCWADVHYTTNENGETVEESKEKVANVIQTEDVKVEEGKADPSQIVGEKIGGGRYLVVDETGGLLVTTMAERMGILNPLAPEEILQKALAEDKQHEETLVPEEPTVDADIDVAETEAMDVDTDVVMNNELSEKDLPEHYHKDDLEVPFAGSNTLTLVHANGQPNLSVLRFYNYDMSIPNPPYSTQPLYSRLLTINWLQLLSPEKDHVYTDTPASMSDEELTAIKASRRGTYHRKRRRWARTRYIVDSTRAGGFAGLVVASTMDPVSVLRATLPLLAPGAPVAVYSPTIEPLAALNDCFSVPRRGAWVALPPPEAVGMSVEELERWQGSEDFPINPSLLVGPSVQSSRARHWQVLPGRTHPLMTSRGGAEGYIFTGWRAVPVQGQIAARGLYKRRRTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7N3</accession>
    <name>A0ABR3Z7N3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pumilio domain-containing protein C56F2.08c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_003172</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000071">
        <property type="protein sequence ID" value="KAL1895534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052645">
        <property type="entry name" value="Pumilio_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47093">
        <property type="entry name" value="PROTEIN JSN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47093:SF1">
        <property type="entry name" value="PROTEIN JSN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00806">
        <property type="entry name" value="PUF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="444"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="PUM-HD" evidence="7">
        <location>
            <begin position="584"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="4">
        <location>
            <begin position="649"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="4">
        <location>
            <begin position="685"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="4">
        <location>
            <begin position="722"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="502"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="940"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1094"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="45"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="129"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="249"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="553"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="954"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="978"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1036"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1100"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1117"/>
            <end position="1147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1167" mass="125799" checksum="8ADF8EE19C5DDFC6" modified="2025-10-08" version="1">MASQHNKMTLSGFIPPANRTSSPTASNSSNDPPPVRSPYGLQAPGSGQSNPTSRPGTASPNRELGSLNPNSGRLMPKRARELQYHEAGGAPGLPNPWGGPPTSGNSTPLRENIPESPTDGFPDFGTVEASGAFGAPSAPAAPTTTRRARAGTVPSRWSPGGATGLPGIPPLNAAPGPLRPPTMPFKSHPLDVDSGSASTVLSRLRAGSMPQAMPFPVNTIPLFSGPSNFNGWARGPTRERGATLASIASVGSNGPSSPSHSAFRADGSESEGMRTLDYLGLAETPQPTLATPIYLENIDDNIRGNRFRSYSVNNTDKYEDEEDAMDEAMILQSQAQELQERIIATHTAITHHNMAVQALASQAPFLTRPRARTAGVLDTPGARLLGTYHSTQNLTANLVPPELRMGSETEYEEMSQAVNAMSINRASSRGVNPEEQGLIEGPTCALWLGNIPTSTTTSTLTEMFKNFGQIISVRVLTHKNCGFVNFDSNEAAAAARREMNGKEIFPGSGPIRINYAKPPSQSNTPSNEGAFPSPSPDTATREQPDVEDTAVAPQPPSAPPTIPLSELANQIRVMAEKFSEGPRREDDDIPRVEERLARAIAYDSYYPEIPPVRESNHSRMYDAPKLRDIRKRIDNQTMHREEIELTAIQMLPEVAELSSDYLGNTVVQKLFEYCSDDVRDQMLERVAPHLAEIGVHKNGTWAAQKIIDVCKTPKQMTMIADNLRPYTVSLFLDQYGNYVLQGCLKFGTPYNDFIFEAMLRRMWEIAQGRYGSRAMRACLEAYACGKDGQRMMAAAIALHSAQLATNANGALLLTWYLDSCTFPHRRALLAPHLAEHLILLCTHKVAYLTVLKVVNQKAEPEARDIIIKAMFFSPEQKTLEGILKDHSCGATLIFKVLTTPFFDDNIRPQVIETVKSVLIAIKAQPNQGYKRLMDEVGISTRNTGAPNAPREAVTTEQRPKSASRQNQGPTGMAPPQGPSQTKGQQPNNAPYYNNGPSKSNNPTPQPSGGYSTPARSEGGESGMTPFPSFGPVASAFAQQNPMSSQAMPPYHGGPQGHQSSGPPRGGPMGNYYPPMGGNGYNGGYPADQYRGMSATAPGMGNSNNPQGISPNYPPGLNMSGNSQYGYNNNGHNMSQMPPMGYNNNGMPQGNGQGSQGQAQDNSRRGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7W5</accession>
    <name>A0ABR3Z7W5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 18">3-isopropylmalate dehydratase</fullName>
            <ecNumber evidence="6 18">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16 18">Alpha-IPM isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17 18">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="primary">LEU1</name>
        <name evidence="22" type="ORF">Cpir12675_002695</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 18">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 18">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 18">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="6 18"/>
    <dbReference type="EMBL" id="JAWDJO010000055">
        <property type="protein sequence ID" value="KAL1896673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01583">
        <property type="entry name" value="IPMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01577">
        <property type="entry name" value="IPMI_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="entry name" value="Aconitase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="entry name" value="Aconitase, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01026">
        <property type="entry name" value="LeuC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01031">
        <property type="entry name" value="LeuD_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004430">
        <property type="entry name" value="3-IsopropMal_deHydase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004431">
        <property type="entry name" value="3-IsopropMal_deHydase_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012235">
        <property type="entry name" value="3-IsopropMal_deHydtase_ssu/lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050067">
        <property type="entry name" value="IPM_dehydratase_rel_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033941">
        <property type="entry name" value="IPMI_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033940">
        <property type="entry name" value="IPMI_Swivel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00170">
        <property type="entry name" value="leuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00171">
        <property type="entry name" value="leuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002458">
        <property type="entry name" value="PRK01641.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004016">
        <property type="entry name" value="PRK05478.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009116">
        <property type="entry name" value="PRK12466.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43822:SF9">
        <property type="entry name" value="3-ISOPROPYLMALATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43822">
        <property type="entry name" value="HOMOACONITASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001418">
        <property type="entry name" value="ACN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="Aconitase iron-sulfur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10 18" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="15 18" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0408">Iron</keyword>
    <keyword evidence="13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 18" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="14 18 22" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha" evidence="20">
        <location>
            <begin position="13"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase A/isopropylmalate dehydratase small subunit swivel" evidence="21">
        <location>
            <begin position="544"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="491"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="500"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="527"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00031631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00033368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRNR" id="PIRNR001418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAL1896673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="780" mass="84729" checksum="6CE804878A4DDECB" modified="2025-10-08" version="1">MPSAEGKPRTLYDKVLQDHIVDQKADGTSLIFIDRHLVHEVTSPQAFEGLKNAGRQVRRPDCTLATTDHNVPTTSRKGMKDIASFIEQEDSRIQCTTLEENVKDFGLTYFGLGDNRQGIVHVIGPEQGFTLPGTTVVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQCLITKPSKNMRVQVDGELTPGVSSKDIVLYVIGKIGTAGGNGCVIEFCGSVIRGLSIEARMSICNMSIEGGARAGMVAPDEITFNYLKNRPLAPKFGSEEWDRAVAYWKGLKSDPDAKYDIDIFIDGKDIPPTVTWGTSPEAVISISGKVPNPEDDEQFPTESSKASARRMLKYMGLTPGVPMEDVVVDKVFIGSCTNSRIEDLRAAAYVVKGRKIASNIKSALVVPGSGLVKKQAEAEGLDKIFVDAGFEWREAGCSMCLGMNPDILSPLERCASTSNRNFEGRQGAQGRTHLMSPVMAAAAGIAGKLADVRKLTQYTATPHVQAAITPDEPAHVDESVEGDDHQKEVIGDQPEDNASHTNTSVPKSAGSSPDLPKFITLKGPAAPLDMSNVDTDAIIPKQFLKTIKRTGLGTALFYEHRYLPDGTENANFVLNKPQYRKSSILVVTGPNFGCGSSREHAPWALNDFGIRCVIAPSFADIFFNNTFKNGMLPIAITNQEHLTAIAQVARENREIEVDLPNQLIKDDAGNTICSFDIEEFRKHCLINGLDDIGLTMQLEDKIAEYELRMSKNTPWLDGHAYLKLGKDGRLAAKAVALPKTNRGEVKTQPLDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z962</accession>
    <name>A0ABR3Z962_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elongation of fatty acids protein</fullName>
            <ecNumber evidence="10">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_002452</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>an acyl-CoA + malonyl-CoA + H(+) = a 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:50252"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:50253"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="10"/>
    <dbReference type="EMBL" id="JAWDJO010000048">
        <property type="protein sequence ID" value="KAL1897196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF169">
        <property type="entry name" value="ELONGATION OF FATTY ACIDS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="384"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="449"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="461"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1897196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="472" mass="51620" checksum="1BDE42B19488BE8A" modified="2025-10-08" version="1">MDTLPFTYLISPSFKLPSGAEPFAVPPPPAGSFAHAPPFDIPESWWVSVLDARVPVTIAVVYAITAKVLTSYNLSHNKQPWAISKTRAFKVFVVMHNVFLAVYSAWTFVNMAGAMHRAIAGPNGPNGITATVDSFCQINGVPGFDGGVFFNEETGKYATLGNNAGIDPATGRPSRYATGRLWNEGLAFYGWWFYLSKFYEVLDTVIILAKGKPSSTLQTYHHAGAMMCMWAGIRWMAPPIWLFVVYNSLIHSLMYTYYTVTAFNIRVPMVIKRTLTTMQITQFLVGVVCAMSYAFVAYALPMTVQVAETVAAAEPQHTASMAEANNSVLSTLKQMVIGVMTKAADVAAAASSTAAVKPSAAPTNYRTETVYVTQNCVNSSGVQFAVWLNVFYLAPLTYLFMSFFIASYTRRGRTDARKSGKVQVAEAQLIDVQRAEKAGWEAAKSVEKEVYGQDGASSPKRVTRSTRSKSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9A1</accession>
    <name>A0ABR3Z9A1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NodB homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_002428</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000047">
        <property type="protein sequence ID" value="KAL1897246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10951">
        <property type="entry name" value="CE4_ClCDA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF2">
        <property type="entry name" value="CHITIN DEACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0170">Cobalt</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="NodB homology" evidence="7">
        <location>
            <begin position="26"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="235" mass="26394" checksum="45D7E847B75BF931" modified="2025-10-08" version="1">MLANNSAVIQTAIAPGAFIMECKVPGTMAITFDDGPYLYTDDLLDILSEYDVSATFFINGKNIGRSLDRDKFKQKIVKRAYSEGHQIGSHTWSHRDLSVTKGAAREQQMTELEDTLIDIIGVKPTYMRPPYGSCDAQCMAHMANMGYRVIHWSLDTLDYGVRTVDEMTVVEESFEKKLPTNTEEPGPIVLAHDSLELTVYQLAVPMIEKSLEAGFQLVTVGECLGESRKLWYKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9C4</accession>
    <name>A0ABR3Z9C4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nuclear envelope morphology protein 1</fullName>
            <ecNumber evidence="4">3.1.3.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">NEM1_2</name>
        <name evidence="4" type="ORF">Cpir12675_002832</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000059">
        <property type="protein sequence ID" value="KAL1896428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011948">
        <property type="entry name" value="Dullard_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02251">
        <property type="entry name" value="HIF-SF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="FCP1 homology" evidence="3">
        <location>
            <begin position="339"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="535" mass="58669" checksum="F63F44244D2811F6" modified="2025-10-08" version="1">MNSLNIISSRVSPQNSPTPSRTNSFSSLGLMRSIEGHHGHSSLDDTPESDDPTIDAKLQPIQLNDPDSISNLAHASNPLTQSDPPLDASFDSAQNIKSGPSPSNATALTAKTSWLAVPQRIASCVIGSLRWILSTIAAPGFYLLALFYDKTGRFRPLLPFRTLFDALGLGFLSGSGAPKSKAGEKHSRPRSASTRHRRKPISTSTSTSLSSQTRSSGASKRKSSISMSSDSDTPSRRRSSATSRPRDGSQDTSTPSRSIRIKVQASDEALKERRHRKTGSSVSRAKASGDGLSTDISAQIKSPTSQAGSAITKYPRAPAPPRPLIPRRQPSYLNFEGPPSEHQKTLILDLDETLIHSMSKGNRLGSGHMVEVRLNTAFVGMGGQMAVGPQHPILYYVHKRPHCDDFLRRISKWYKLVVFTASVQEYADPVIDWLESERKYFAARFYRQHCTFRQNAFIKDLSAVEPDLSKVMILDNSPLSYMFHQDNAIPIQGWINDPTDNDLLNIVPLLEGLQYVSDVRALLALRGGEDGQHMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9D8</accession>
    <name>A0ABR3Z9D8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Branched-chain-amino-acid aminotransferase-like protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002476</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000048">
        <property type="protein sequence ID" value="KAL1897219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053226">
        <property type="entry name" value="Pyrrolopyrazine_biosynth_F"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48419">
        <property type="entry name" value="SULFOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48419:SF1">
        <property type="entry name" value="SULFOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13469">
        <property type="entry name" value="Sulfotransfer_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="306" mass="35702" checksum="B4AA98AAC1A95769" modified="2025-10-08" version="1">MTVPTKPIFVATHPRACSTAFERVFMARRDILQCVHEPFGDAFYYGPERLSERFEQDEEARRKSSFEKTTFADVLQHVKDAGDEGKRVFIKDIAYYLLAPDGKSTKVAASFNVGEEPENPTTIPLEELQKFQFTFLIRHPRRSIPSYYRCTLPPLVEMTGFDRFMPNEAGYAELRRLFDYLIKSGVVPKDRIVVLDADDMLDQPEKVIREYCARTDINFTPNMLEWTEEDDKRAKEAFEKWKGFHEDALASSSLRPRKHPQTPVSREEDDASWRVKFGETGQKVIRQCVDDNEEHYNYLKQFAIKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA27</accession>
    <name>A0ABR3ZA27_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Splicing factor subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_002485</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the SF3B5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000049">
        <property type="protein sequence ID" value="KAL1897164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009846">
        <property type="entry name" value="SF3b5/RDS3-10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017089">
        <property type="entry name" value="Splicing_factor_3B_subunit_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20978">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20978:SF0">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07189">
        <property type="entry name" value="SF3b10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037010">
        <property type="entry name" value="Splicing_factor_3B_subunit_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="81"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR037010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="94" mass="10900" checksum="70AF76748052C4CF" modified="2025-10-08" version="1">MADKLRAQQELERLQAKYIGTGHPDVSSWEWKTNIQRDTLSSIAGHPGMVNYMAVAENEPLHMVRTRMIRKMMQPCGPPPMREEDMPMRMDESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBR6</accession>
    <name>A0ABR3ZBR6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002067</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000036">
        <property type="protein sequence ID" value="KAL1898118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039123">
        <property type="entry name" value="PPTC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320:SF24">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="50"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="418" mass="45621" checksum="538DAEF10B3D8FF1" modified="2025-10-08" version="1">MREAQQNHGDNAAREPRRLSLSITEAYHEGTLFRVPLVPPPYHRRLLSSSQLQNPSPVESVLPDHSAPASTSTHQPTTSAPVPPIPPSAADSGPIAALPKLPFRFETGIGLFAKRQPRPFPPPFLSPPSGSFSDPLSTHRKPKVDGQFIRGLTNGDDAVYASDYFICANDGVGVWSKRPRGHAGLWSRLILHYWVAAMEKDTLRHANSLSATPGLDPNYQPDCVQYLQEAYERTLTITAGPNECNGTTTASGAQLHFRLAPDSGNTPSTQPIPVVHVTNLGDCEVLIVRPSTHEVLFKSVEEWHWFGCPRQLGTNSPDTPVQNAKYNVVDIQVGDIVLAMSDGVIDNLWEHEIVDVVTHSLERWEANEAGEQQACTRMAYTADALLAAAKVVATDPFAESPFMERAIEMGLASEGGMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBU1</accession>
    <name>A0ABR3ZBU1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">asparagine synthase (glutamine-hydrolyzing)</fullName>
            <ecNumber evidence="1">6.3.5.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ASN1</name>
        <name evidence="13" type="ORF">Cpir12675_002362</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-aspartate + L-glutamine + ATP + H2O = L-asparagine + L-glutamate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12228"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.4" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000045">
        <property type="protein sequence ID" value="KAL1897506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00712">
        <property type="entry name" value="AsnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006426">
        <property type="entry name" value="Asn_synth_AEB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050795">
        <property type="entry name" value="Asn_Synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033738">
        <property type="entry name" value="AsnB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01536">
        <property type="entry name" value="asn_synth_AEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006949">
        <property type="entry name" value="PRK09431.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11772">
        <property type="entry name" value="ASPARAGINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11772:SF2">
        <property type="entry name" value="ASPARAGINE SYNTHETASE [GLUTAMINE-HYDROLYZING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001589">
        <property type="entry name" value="Asn_synthetase_glu-h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="12">
        <location>
            <begin position="2"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="553"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="553"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1897506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="573" mass="64551" checksum="AEE61DF7411FA686" modified="2025-10-08" version="1">MCGIFACHRHPDVQAFKPTALKLSKLIRHRGPDWSGSVISNNTILCHERLSIVGVESGAQPLTNSDETIILTVNGEIYNHRSTRKNLHNSYHFKTASDCEVVIPLYEKYGKDAPSHLDGMFSFVLYDKKQDRIIAARDPIGITTLYQGWSSKEPETIYFASELKSLAPVCDKIEAFPPGHVFDSLTGERTRYFNPSWWEPSRIPTSPLDLTAIRESLEKSVRKRLMAEVPYGVLLSGGLDSSLVASIAQRETLRLKEAALASKGEQTKNPDTGEGLVGMDDENHLDTVTYLPQLNSFSIGLPGSPDNEAALKVAKFLGTKHHVMTFTVEDGLNALSDVIYHLETYDVTTIRASTPMYLLSRKIKAMGIKMVLSGEGSDEIFGGYLYFHAAPDAKSFHEETVNRVHNLHLADCLRANKSTSAWGLEARVPFLDKEFLETCMNIDPKEKMITEGKIEKHILRKAFDTKENPYLPDDILWRQKEQFSDGVGYGWIDALKDNAELQVTDEMMKNPKAEWGTDIPDTKEAYWYRLMFDELFPQACASTVMRWTPKWSKQTDPSGRSISIHNAKYETTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCC4</accession>
    <name>A0ABR3ZCC4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000035">
        <property type="protein sequence ID" value="KAL1898293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="527"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="612"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="204"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="545"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="662" mass="69887" checksum="7A8A6F2E8F0FE45E" modified="2025-10-08" version="1">MSTGPSSVVTQRARRQATRTLQWASVARHNLPRPNTVLARSKSSSNSQSRRSLNHKARQATSTPSASASASASSVNGYSSLSEPGEISSDDEATATPQLSSLVNADRARIAATPTSTATKGTTLAYAANQVSDVRLTFTTTISKLFPNVPPVPLAPMYMPRLVDSSMTAAVDDASTALPSIILNQGGSGSGSSLAIAPTGGYGNSQNSSGNSGSLAQQGTAASSPSSTATSTANSHSSISTNETIAIASASIAGAVIIGLSIWLFWRVRRVRRAAAVTPSSSSARSMPAYGKNHNKPPKSFIGCISSKIPFVGHKWPDTTDSSPASWNNVEAGNMPVNQQRSMSPQSQNWPSATEEKLAMNNASYYGPAVVTSVPSIHTNNLSREIPISDSATPISATSNNPLLLPSPYTPVYGSEANWAAAKEMNLSPDGTTPVDCMTGTLTEPYMAELTYNSSLHSSGADYGGEDTLRAVTLQQLQSPDGSIVPPIFDDGVYGRPQSGPGDYRYSELSSISSGFGDADIIIPSNAGSPVASPYARASTRRSAHSSTMRSRPLLHTALSSRSSSAPRTPPPVAMRQSWSRPPTSGYRDRDTVMTTVTDDGQPHRFRTVSSWVQQQSSRARRAQRRAEKNGVVPQVPDEPQLTLMMPDGEVPRPVDMTIARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCK2</accession>
    <name>A0ABR3ZCK2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptide hydrolase</fullName>
            <ecNumber evidence="3">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_001881</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000032">
        <property type="protein sequence ID" value="KAL1898416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03880">
        <property type="entry name" value="M28_QC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037457">
        <property type="entry name" value="M28_QC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040234">
        <property type="entry name" value="QC/QCL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12283">
        <property type="entry name" value="GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12283:SF6">
        <property type="entry name" value="GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M28" evidence="5">
        <location>
            <begin position="106"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="352"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1898416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="383" mass="42595" checksum="723327DFBA9BF967" modified="2025-10-08" version="1">MTTANAFKELSDDVLHLLPEVGDDFAIDNPRGLLAPLLITRVPGTPGQIAAQRHFIDFFSQSLPKWDIGIHNITSKTPVTGDDEIPFVNLFFTRDPPWASGGDVGRLTLVAHYDSKYTPKGFIGATDSAAPCAMLMHVARSIDQALTDKWDAVEASGEAGMDEERGVQILLLDGEEAWEKWTDEDSLYGSRALAEDWESEAYPAMSTFRNRLSSIDLFLLLDLLGSPNPKVPSYFVTTHWAYHNMAMLEKRLRSLGKLESTVTAPFLPEIDKVAEDFKYPSGISDDHLPFMHRGVPILHIIPSDFPSVWHKIEDDGKHLDIAVCHDWAKIVTAFAIEWMELEDYIILARKGESGSSPKVRRDEGSQEGDGDAHGQYASARSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD64</accession>
    <name>A0ABR3ZD64_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Enolase</fullName>
            <ecNumber evidence="4">4.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">2-phospho-D-glycerate hydro-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">2-phosphoglycerate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ENO1</name>
        <name evidence="14" type="ORF">Cpir12675_002040</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(2R)-2-phosphoglycerate = phosphoenolpyruvate + H2O</text>
            <dbReference type="Rhea" id="RHEA:10164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.2.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the enolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000036">
        <property type="protein sequence ID" value="KAL1898092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03313">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="entry name" value="Enolase-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="entry name" value="Enolase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020809">
        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01060">
        <property type="entry name" value="eno"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902:SF1">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03952">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001400">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00002">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00178">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01193">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="Enolase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="Enolase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="8 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enolase N-terminal" evidence="13">
        <location>
            <begin position="3"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Enolase C-terminal TIM barrel" evidence="12">
        <location>
            <begin position="143"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1898092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="438" mass="47483" checksum="5DEECDBBF0A896CB" modified="2025-10-08" version="1">MAITKIHARQVYDSRGNPTVEVDVHTETGLHRAIVPSGASTGQHEACELRDGDKSAWGGKGVLKAIANVNDTIAPALIKENFDVKDQSKIDEFLIKLDGTTNKTNLGANAILGVSLAVAKAGAAEKKVPLYAHISDLAGTKKPYVLPVPFMNVLNGGSHAGGRLAFQEFMIVPCEAASFTEAMKQGAEVYQILKSLAKKTYGQSAGNVGDEGGVAPDIQSATEALDLIVAAIEKAGYTGKMKIAMDVASSEFYKVEEKKYDLDFKNPESDPSKWLTYEQLAALYKELAEKYPIVSIEDPFAEDDWEAWSYFYKTNDIQIVADDLTVTNPLRIKKAIELKSANALLLKVNQIGTLTESIQAAKDSYADNWGVMVSHRSGETEDVTIADVVVGIRSGQIKTGAPCRSERLAKLNQLLRIEEELGEEAIYAGSSFRTSVNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDE1</accession>
    <name>A0ABR3ZDE1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ski complex subunit Rec14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rec14</name>
        <name evidence="5" type="ORF">Cpir12675_001808</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000030">
        <property type="protein sequence ID" value="KAL1898701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051510">
        <property type="entry name" value="SKI8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44090:SF1">
        <property type="entry name" value="SUPERKILLER COMPLEX PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44090">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="287"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="144"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1898701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="369" mass="39323" checksum="D8CAC3051CE15B62" modified="2025-10-08" version="1">MADESKITWYYTLNHRSFRDEKACGANASQSKQYLTAHTVDRAHLATIFAIAVTPKVVLSGGGLSSLAVHDSTKPDFPLLQTIKGANPTGCHHICASRDGRVAASASFSGDLKVWSSDPTTGEWKLLTALQTGKNEAGGLGGESSVSDANPSQPAADGRSSRNGVWAVAISETGERLAATTVDNRALVWVARNGAMMLEHTFDGFNESFGTCVAISGDDRLVATGHQNGSAYVFSTETGRLMYSLSSLARPLRAISFSPGGSLLATAGDANIIAIYDVKHGEHIGNLKGHAAWITSLDWNDSGEYLASAALDGRVKVWSIDRLECVATHSETDEPLWAVRWLPKMGRSELFVTGGASRSLTFYREATGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDF5</accession>
    <name>A0ABR3ZDF5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cyanovirin-N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000044">
        <property type="protein sequence ID" value="KAL1897529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.60.10">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011058">
        <property type="entry name" value="Cyanovirin-N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036673">
        <property type="entry name" value="Cyanovirin-N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08881">
        <property type="entry name" value="CVNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01111">
        <property type="entry name" value="CVNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51322">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyanovirin-N" evidence="1">
        <location>
            <begin position="55"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="187" mass="20518" checksum="BAAA4660B87C2788" modified="2025-10-08" version="1">MSKVISSSAPSLVQILAIFFFAFASNALCLSIPRTRPVDYQISGTQTVAHGSGTAFGDSCRNVKLNASFYGEPEEHYSHVNAKCQSDEGKYVPSSLNLNQYIGNFDGKLKWDVRGGFTESCFDCYLRRHSSWKQFTVLHCVCKRAGEKGPVWFPSKTEIDLDTSILNIAGELVAVGISEHTPVSSPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDH3</accession>
    <name>A0ABR3ZDH3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_001874</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the flavin monoamine oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000032">
        <property type="protein sequence ID" value="KAL1898409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050281">
        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742">
        <property type="entry name" value="FLAVIN MONOAMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742:SF386">
        <property type="entry name" value="LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04433">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="966"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="966"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1898409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1145" mass="126924" checksum="5B4D0008574DC93C" modified="2025-10-08" version="1">MNLGSGRTSSPVQAPALAPALAPALSPDGHPEPGRGACMKHNKANTSLSSLSDFESFTSHADDYGEQNVKVDGDSQYMIYKAETTASKSGDIVMNEDEHICSSNNSTPVSNQDDRADGITVSHDEDLTATIPGTYSSASSPFHDNFDRSDISLLTPSNIASKATTPIYAVDQTISLSTSLPNSFRPEHTPKIQNSIPSLAIPSPTTLGELEKIYIQPRSSIPHHIQPSEYASQCITAAEMCRLNPYALHLGENKLLRAYISRSQVTTYLNIRNGIARLWARNPQVAVLRKEAIGCAGRGWFKVASLCYDWLVRNGFINFGCVQYPRQSVCLPRGTKRQKTIVVIGAGMSGLGCARQLDGLFQQYSHDFISRDEEPPRVLILEARNRVGGRVYSKPFESKPEDGFKFEDKRCTAEMGGMIITGFYGNPLNFLVRGQLGLQYHCLRPETTLYDSTGFPVDIKSDQLVEHLFNDSLDRVSEYKFDIKVPPLVVGNVQFISEVRDSSSDGGWTLKQIDDAGNIESPPLLQRQLVSDEIRSVGNLSKYGCASIKAKGMGWPLKSGIETATTINLDAAAHAEKACMGSVFEEAISQYTQILDLNPLHFRLLNWHVANLEYSNATDLHNLSLGGWDIDAGNEWEGKHTMVIGGYQSVARGLLMCPQTLECRFNSPVQKIVYDPEAASTGHDRKCAVICEDGTTIDADYVVCSIPLGVLKAGNVCFEPPLPEWKKGAITRIGYGVLNKVILTYQEAFWETDRDIFGILRDPLNPESVSQEEYAESRGRFFQWFNVSSSSGLPCLLALMAGKAGYAAEKEDDKSLVQEATTLLRKVFGKNVPYPKEAIITRWASDKYSFGSYSSSGPGMEWDDYDTLAKPLGNLFFAGEHTIGTHPATVHGAYMSGLRAASEVFDSLLGPLQVPEPLFPAKQASGSSLKRKATTLQDIEKQLRHQHEQHFQEFVVAKLGPALVHPKPPPSNVYSFFRRENTSVIRQRCLSRRHYPKGKIPPKDMSQMASKMWRELSPDERSLCEKRYQTVIVEYKNLINDLPRAEMTRQSQVAELREQFDKLFPLEDPHQQNQKDISVKPAGTHKIERHEPETDKTAVVGIALQEVRDPMFIDTESGTIRLSGLPARKTKVVSYVEDDSDLEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDM1</accession>
    <name>A0ABR3ZDM1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L30</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL30</name>
        <name evidence="5" type="ORF">Cpir12675_001901</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000032">
        <property type="protein sequence ID" value="KAL1898434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00481">
        <property type="entry name" value="Ribosomal_eL30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000231">
        <property type="entry name" value="Ribosomal_eL30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039109">
        <property type="entry name" value="Ribosomal_eL30-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022991">
        <property type="entry name" value="Ribosomal_eL30_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002172">
        <property type="entry name" value="PRK01018.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11449">
        <property type="entry name" value="RIBOSOMAL PROTEIN L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00709">
        <property type="entry name" value="RIBOSOMAL_L30E_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00993">
        <property type="entry name" value="RIBOSOMAL_L30E_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="4">
        <location>
            <begin position="13"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1898434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="109" mass="11789" checksum="DAAED994E378E895" modified="2025-10-08" version="1">MAPVKKSKRDAQNISSKLALVMKSGKVTLGYKSTLKSLRSGKAKLVIIASNTPPLRKSELEYYSMLAKTNVHHLNGTNIELGTSCGKMFRCSTMAILDAGDSDILSEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE30</accession>
    <name>A0ABR3ZE30_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SprT-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001853</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000031">
        <property type="protein sequence ID" value="KAL1898649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006640">
        <property type="entry name" value="SprT-like_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035240">
        <property type="entry name" value="SprT_Zn_ribbon"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23099:SF0">
        <property type="entry name" value="GERM CELL NUCLEAR ACIDIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23099">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10263">
        <property type="entry name" value="SprT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17283">
        <property type="entry name" value="Zn_ribbon_SprT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00731">
        <property type="entry name" value="SprT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SprT-like" evidence="2">
        <location>
            <begin position="316"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="534"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="566"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="578" mass="64242" checksum="8DD71391646F0C96" modified="2025-10-08" version="1">MLQGPARPLLSPKKAPGSTVKIRRFAHSQTLENPLLGKIDRGKSQHGWIDLDQKLLGLRDNESPDTRKLRTRGSGIKPASRGRSMASFLSFSNGSDNDDISHTGSDLDDSHCSGLDDFVPVLVPNSLKIRDGMDADTTLRMSWREPRRLTEFDKNDLTIVEGPNQHIEKSKVDEISSSSNDPSSAVDVSQIDPSIADSLALSMGKRLPVSDQLSGSVTLTPSSGPTTNPALLRKLTENPAWCQDIASDFDDSSDSDITGFVPSKLPRTDKKGKSTSPIKKSSQASSPRNIKKEFEATKHEMATNFLAELDVAITKGKIAEMTQSTGGVQIVWSNKLNTTAGRANWSRKTSITKVEGQQEIVEHKHFASIELATKVIANEERLLNVIAHEYCHLANFIINNLKTNPHGREFKAWATQVSNAFGHRGIEVTTRHSYDIDFKYAWECSSCGLEYQRHSKSINPERQRCGKCKSVLVQTRPTPRSASGKPSEYQLFMKIQMKAIKAKNPTLKQKDIMRMVGDLWAEHNRNKELAIATPATQVVRVDEEEEEEEEEEEEEGEEEEENLDELLAAQLTGLTLQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEC6</accession>
    <name>A0ABR3ZEC6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tetratricopeptide repeat protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000029">
        <property type="protein sequence ID" value="KAL1898760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052769">
        <property type="entry name" value="TPR_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46014">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46014:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="207"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="324" mass="34490" checksum="8DACF825B263237E" modified="2025-10-08" version="1">MSSPVTSSQPRAIDDDLLSEKVATLEQETALLLESNTCKAAANTLFTAGDYRNAFNKYHEAFLSCPKPRLFEAAVLHSNIAACQLKLQEWPEAIKSASSALAELDKLEQLKQDIPPDSAPTLLDSPPPQAGEGDADEEIISAGAAKAQPLPPPPLSAEKSDILRIRCKALMRRARARSEVGGWQNLVGAEEDYKLLAGISPAPAPTPSAASSATTTTTTTPPTPVPAVTKTTDSPVPPPQSPNFNAGVHTILSPADKKIVRAQLAALPPRIKSAQEAEMAEMWGKLKSLGNGILKPFGLSTDNFQMAKDEKSGGYSMNFNQNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF00</accession>
    <name>A0ABR3ZF00_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chitin-binding type-4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001923</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000033">
        <property type="protein sequence ID" value="KAL1898378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182:SF2">
        <property type="entry name" value="LYTIC POLYSACCHARIDE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045241676" description="Chitin-binding type-4 domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="403" mass="41902" checksum="307698B06CCB04DA" modified="2025-10-08" version="1">MTPFSALFAAMLAVASTASAHMKITSPVPINAASFNNFPLAADGSDFPCKFGSNGYEYSSDSTENKYSVGSNDNHLAFMGSAVHAGGSCQVSLTYDRPPTKDSVWKVVTSFEGGCPAKDQAGNFPVEDPNYIDPYTYNFTIPEGLESGQYTLALTWFNKLGNREMYMNCALATLEGTGGDKSVYDSLPNMVVANVGNGCSTPPATDLQYPDPGLNLQLFNGATEAWGNLVGTCTAFTGPAVSSLPAGTAPSYPTQVAQDSTAPSYGVPTNAPGGAYAPSGGSQAMPTKYVPSGGLFLATSDVKVTATPTMTYYSPTPTPTSNVVSDSAYEAGTSCDFSQEGVWNCIGESSFQRCASGEWSAVTQLASGIVCTPGKSKDFVYKASGSGVKRALRVGAKMVGFSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF62</accession>
    <name>A0ABR3ZF62_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">H(+)-transporting V1 sector ATPase subunit D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">VMA8</name>
        <name evidence="5" type="ORF">Cpir12675_001675</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the V-ATPase D subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000027">
        <property type="protein sequence ID" value="KAL1899015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002699">
        <property type="entry name" value="V_ATPase_D"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00309">
        <property type="entry name" value="V_ATPase_subD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11671">
        <property type="entry name" value="V-TYPE ATP SYNTHASE SUBUNIT D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01813">
        <property type="entry name" value="ATP-synt_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="226"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="247"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1899015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="256" mass="28742" checksum="2B5D6C8462A78533" modified="2025-10-08" version="1">MSGAADREPVFPTRQSLGLMKAKLKGAETGHSLLKRKSEALTKRFREITRRIDEAKRKMGRVMEIAAFSLAEVTYAVGGDIGYQIQESAKSARFRLRTKQENVSGVLLPAFESYQTEGNNDFGLTGLGRGGQQVQRCRETYARAVEALVELASLQTAFVILDEVIKVVNRRVNAIEHVIIPRTENTIKYINSELDELDREEFYRLKKVANKKQRDTAAADLELKARRAAKGQPSEDENGDHLKDLLADGDEEEVIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFG9</accession>
    <name>A0ABR3ZFG9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">N-alpha-acetyltransferase 20</fullName>
            <ecNumber evidence="4">2.3.1.254</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">naa20</name>
        <name evidence="4" type="ORF">Cpir12675_001700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.254" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000028">
        <property type="protein sequence ID" value="KAL1898947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120518">
        <property type="term" value="F:protein N-terminal-methionine acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051646">
        <property type="entry name" value="NatB_acetyltransferase_subunit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45910">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45910:SF1">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="2"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="190" mass="22058" checksum="CEB54EA92F4DA0C4" modified="2025-10-08" version="1">MATFRRFKPDDLNKFSKCNLDPLTETYEIGFYLQYHATWPAMFQVCEDADGNIIGYIMGKVEESPPIYKNTEHYLPWHAHITALTVAPSARRLGIGKILTDQLERAADDNDAWFVDLFVRKSNEKAIAFYEGLGYSIFRTVEAYYGDHSTDPTATSEDAYDMRKPMKRDIKKEHIREDGERFIVNPEDVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFV9</accession>
    <name>A0ABR3ZFV9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001366</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000021">
        <property type="protein sequence ID" value="KAL1899598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34706">
        <property type="entry name" value="SLR1338 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34706:SF1">
        <property type="entry name" value="VWFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="70"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="310" mass="33897" checksum="A5389C4FE4D87960" modified="2025-10-08" version="1">MGEDQPVGSHQEPPPPYSSATNYSLGSPGTPDLAASTPRASLKEIKASRRRAILATSTDDDPYAFLSSFDTAFVIDDSGSMYGSNWAETQEVLKAIMPICISHDTDGVDLYFLNYKSKYAAPCETKGPNGFYGIKSPAEIQKIFDSINPYGTTPTGQRLQSILAPYQRSLADAYERSKEKGALVEPIKPINVITITDGRPSDDVEGVIVPVARRLDSLDAPPYQIGLQFFQVGSDANATAGLRELDDELEEMNIRDIVDTVFWDGELGTGLSSDLILKTVLGAVNRRLDRKRCDTPPARDRLVRAQEKCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG22</accession>
    <name>A0ABR3ZG22_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ENV7</name>
        <name evidence="11" type="ORF">Cpir12675_001323</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000020">
        <property type="protein sequence ID" value="KAL1899646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052239">
        <property type="entry name" value="Ser/Thr-specific_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45998">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45998:SF2">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="6"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="154"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1899646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="427" mass="46184" checksum="C5245D372A85CAD5" modified="2025-10-08" version="1">MYLLVANLRAIIFQGGFSYVYLVQDISNSELFALKKIRCPFGAESVSLAMNEVEAYRAFAGAPGIIHSIDYSIATERGGGEDSKTVYVLLPYYKRGNLQDMINANLVNGTQFPERKLMVLFLGVCRALKTMHQYKGENSSGKARPIERMRMGNEADDDLDSLGSDSSSDSDLDTGKQAMRKFTAKKNKNKKPVNNKRSHHESSFKNATADTGADGDHESAQQKPLMGTSSSAELPATSFAHRDIKPGNIMIDDSGTGPILMDLGSVAPSPLFVTSHSQAVAVQDTAAEHSTMPYRAPELFDVHNGAVIDTKVDIWSLGCTLYACLVGKSPFEARSDETGGSLSLCVLGGDWRFPGEGGLNQGAQRQGTAANLKKAQQDAAAGSKEVVISEPVKDIVRKCLAVEPVERPDIDELIRLVEDAIDVDELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG63</accession>
    <name>A0ABR3ZG63_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">hydroxyacid-oxoacid transhydrogenase</fullName>
            <ecNumber evidence="4">1.1.99.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_001480</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(S)-3-hydroxybutanoate + 2-oxoglutarate = (R)-2-hydroxyglutarate + acetoacetate</text>
            <dbReference type="Rhea" id="RHEA:23048"/>
            <dbReference type="ChEBI" id="CHEBI:11047"/>
            <dbReference type="ChEBI" id="CHEBI:13705"/>
            <dbReference type="ChEBI" id="CHEBI:15801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="EC" id="1.1.99.24"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>4-hydroxybutanoate + 2-oxoglutarate = (R)-2-hydroxyglutarate + succinate semialdehyde</text>
            <dbReference type="Rhea" id="RHEA:24734"/>
            <dbReference type="ChEBI" id="CHEBI:15801"/>
            <dbReference type="ChEBI" id="CHEBI:16724"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57706"/>
            <dbReference type="EC" id="1.1.99.24"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.99.24" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000023">
        <property type="protein sequence ID" value="KAL1899364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08190">
        <property type="entry name" value="HOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1090.10">
        <property type="entry name" value="Dehydroquinate synthase-like - alpha domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056798">
        <property type="entry name" value="ADH_Fe_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042157">
        <property type="entry name" value="HOT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496:SF83">
        <property type="entry name" value="HYDROXYACID-OXOACID TRANSHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25137">
        <property type="entry name" value="ADH_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56796">
        <property type="entry name" value="Dehydroquinate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA" evidence="9">
        <location>
            <begin position="4"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Fe-containing alcohol dehydrogenase-like C-terminal" evidence="10">
        <location>
            <begin position="226"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF25137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1899364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="407" mass="43791" checksum="20E7CFB51B9B5B12" modified="2025-10-08" version="1">MAASSIRFGEGVTREVGMDLKNMKAKNVCVVTDPTVDSLLPMQHVRESLDQEGITYTVFNRVKIEPKDYSVMEAIEWARPFNADVYVAVGGGSVIDTAKLMNLYSVYSEAPLSDFIAAPSGAGRPIDRPLRPLIAIPTTAGTGSETTGTAIFDLTAQRAKTGVAHRNLKPLLGICDPLNTRSMPAAVKASSGLDVLCHSLESWTAIPYTERTPRPTNPLLRPAYQGANPISDIFSLHALRQTVKYLPRAIKDPDDLEAQTEMLLAATLAGVGFGNAGVHLCHGYLVASPIIPHGVSVAVTAPAVFRFTGPSNPERHLQAAEAFGVDVSNAAKSSAGEILGDAIREFLDKLGDQPTGLKALGFKYGDIDQLVEGTLPQGRVLKLAPGLKMEEQEEEKEQLRRLFEDSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGI5</accession>
    <name>A0ABR3ZGI5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">26S proteasome regulatory subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPN9</name>
        <name evidence="4" type="ORF">Cpir12675_001858</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000031">
        <property type="protein sequence ID" value="KAL1898654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054179">
        <property type="entry name" value="PSD13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035298">
        <property type="entry name" value="PSMD13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040798">
        <property type="entry name" value="Rpn9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10539">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10539:SF0">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22037">
        <property type="entry name" value="PSD13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18261">
        <property type="entry name" value="Rpn9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="3">
        <location>
            <begin position="176"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="382" mass="44126" checksum="60350ADAC5904BF7" modified="2025-10-08" version="1">MSFNEKIQDFLADQREAAPEQLQADILEFEDLWERKLWHQLTEKLQTFFKNPASTPCRLPFYNVFVLTFADKINQLKLVQLALNASTECPNNKERLAFLQDVAKRVDTADTRDAMVYASTAVARVKLNIPDLEGARKDLDSCQRLLDRLDSVEPFVHATFYDANASYYQRQNEFADYYRNALLYLACIDISTLSPKERHIRAYHLSVSALVSESIYNFGELLLHPILDALKDSENEWLRDLVFAFNRGDLVAFDSLSNHIESNNLLDEYSTHLRQKIYLASLTEAVFRRPPHDRTMSFKDISAATKVRPEEIEHLIMKALSLGLLRGTIDQVDEIAHITWVQPKVLDKKQVGEMRDRLIEWDQNVNELGNWIEKSGGDLWVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGS2</accession>
    <name>A0ABR3ZGS2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">S-(hydroxymethyl)glutathione dehydrogenase</fullName>
            <ecNumber evidence="12">1.1.1.284</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">FDH1_2</name>
        <name evidence="15" type="ORF">Cpir12675_001747</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 12">
            <text>S-(hydroxymethyl)glutathione + NAD(+) = S-formylglutathione + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19985"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58758"/>
            <dbReference type="EC" id="1.1.1.284"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>S-(hydroxymethyl)glutathione + NADP(+) = S-formylglutathione + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19981"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58758"/>
            <dbReference type="EC" id="1.1.1.284"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>S-nitrosoglutathione + NADH + H(+) = S-(hydroxysulfenamide)glutathione + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:78371"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:145544"/>
            <dbReference type="ChEBI" id="CHEBI:229723"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a primary alcohol + NAD(+) = an aldehyde + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10736"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15734"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a secondary alcohol + NAD(+) = a ketone + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10740"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17087"/>
            <dbReference type="ChEBI" id="CHEBI:35681"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.284" evidence="12"/>
    <dbReference type="EMBL" id="JAWDJO010000029">
        <property type="protein sequence ID" value="KAL1898744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08300">
        <property type="entry name" value="alcohol_DH_class_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014183">
        <property type="entry name" value="ADH_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02818">
        <property type="entry name" value="adh_III_F_hyde"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43880">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43880:SF12">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE CLASS-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 12" id="KW-0520">NAD</keyword>
    <keyword evidence="5 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="14">
        <location>
            <begin position="35"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="13">
        <location>
            <begin position="206"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1898744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="380" mass="40499" checksum="F7B230649D4B5AE2" modified="2025-10-08" version="1">MADTVGKTITCKAVVAWEANAPMKVELVEVDPPKAHEVRIQIHYTGVCHTDAYTLSGVDPEGAFPVILGHEGAGIVESVGEGVTNVKPGDHVVTLYTPECGECKFCKSGKTNLCGKIRATQGKGVMPEGTSRFRCKGQSVLHFMGTSTFSQYTVVADISVVAVQPEAPMDRTCLLGCGITTGYGAARITAKVEEGSNIAVFGAGCVGLSVVQGAVMNKAGKIIVVDINPAKEEWARKFGATDFVNPTQLQGQTVAEKLIEMTDGGCDYTFDCTGNVNVMRAALEACHKGWGESIIIGVAAAGQEISTRPFQLVTGRVWKGCAFGGVKGRSQMRGLVQDYLDGKLKIDEFITDRRGFNDMGTDFEAMHAGNCIRTVVDMRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH38</accession>
    <name>A0ABR3ZH38_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Dihydroorotate dehydrogenase (Quinone), mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">URA9_2</name>
        <name evidence="8" type="ORF">Cpir12675_001128</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04738">
        <property type="entry name" value="DHOD_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050074">
        <property type="entry name" value="DHO_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005719">
        <property type="entry name" value="Dihydroorotate_DH_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH_cat"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01036">
        <property type="entry name" value="pyrD_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48109:SF4">
        <property type="entry name" value="DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48109">
        <property type="entry name" value="DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dihydroorotate dehydrogenase catalytic" evidence="7">
        <location>
            <begin position="111"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="460" mass="49201" checksum="E8E36D525AC9878C" modified="2025-10-08" version="1">MTPLFAQSRRALPEQLRAASRRYISTASPRTSSGSGFKLTAYTAGLAIIGSAAYIYGTDSRASVHRYVIPPLLRTIFPDAEDAHHVSTALLESLYSAGLHPRERTPETPALATSVFGNPLSNPIGVSAGLDKHADIPDVLFDLGAGIVEVGGCTPLAQPGNDRPRLFRIPVLEGLVNRYGLNSHGADAMARKLRERVLRYAISHGVSEEDVLNGAVAVNGADASVPPGSLRAGKLLLVQVAKNKATDQTDVEAVARDYVYCVKRLALYADVLVVNVSSPNTPGLRDLQAVEPLTRLLSAVVEEANKTQRRTRPRVMVKVSPDEDEAAQMSGIVQAVMASGVDGVIVGNTTSRRAGLVAQSVPLTGREQRALQETGGYSGPEMFPRTLDLVSRYRKMFDEQLVGSNKDRMTLFATGGITNGKQALETLQAGASVAMVYTTMVYNGAGTVTRIKDEMAKEMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH68</accession>
    <name>A0ABR3ZH68_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Serine/threonine protein kinase</fullName>
            <ecNumber evidence="8">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">DUN1</name>
        <name evidence="8" type="ORF">Cpir12675_001054</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000015">
        <property type="protein sequence ID" value="KAL1900055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FHA" evidence="6">
        <location>
            <begin position="183"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="274"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="575"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="634"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="583"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="595"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="643"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="693"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="746" mass="85616" checksum="7EF50E9F56FA09CD" modified="2025-10-08" version="1">MPRARDTSPDSGARRRSRRLAAQASLSTAATSVEASSGIRRNRPANGRRANRQVSPEHDERYLASLADDDSYGDYAATPPISRNDHHPIDNVRYGRGVESRDQVHMPSSPGDTQTPSQPIARVNSQLDEVEECEQGVWGYLIVYGNGSYSRIILKREMPRPTSAQRQLGITDRPRNRITPGRFIIGRRQQETDLCISKPALSNRHCILFLEQGNNGSVILEDLSMNGTFVNDCIVGRNNRRVLRNGDRIDLCSQAFFIFNYPQGFQTSIFDSQYIVYHSLGSGQYGQVNLCVEKSTGKRYAVKLFNVDHTDPQRRSVLRQEIGMLMTLDHPNVLQMKDSFHDHDGIRIVLEYIPGGELFEFIVKKGRLREDEARRLFKQVFDGVKYLHDRDIVHRDLKPENILLYSEDLRLVKIADFGLAKIVGEDSFTTTLCGTPAYVAPEVLERKHGYNRAADIWSLGVILYVSLCGFPPFSDELTSRAFPYTMQDQILQGRYEFPSPYWDPICENASDLVESMLQVNPGERLTIDECLAHPWMAGGINPADSTNGLVEGVRGLRVRRGVSRQRTMLADIAAGMRYPGDASHQQRSTPASTTRRREMRPADPRRPEDFMAIGGYGDPVLFDDDLSSTTEATHDITTAGAIRARDRDFGDSHQRQRPRDRDRQRDRERERERERESRAQDGERRNGHRERHRERDREHYRERDRDFERDPDGDRARAGRRERERGDDRREYRRDGDDRRAREGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHM1</accession>
    <name>A0ABR3ZHM1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_001332</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acetyltransferase family. GNAT subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000020">
        <property type="protein sequence ID" value="KAL1899654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039135">
        <property type="entry name" value="NAT9-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13256:SF16">
        <property type="entry name" value="ALPHA_BETA-TUBULIN-N-ACETYLTRANSFERASE 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13256">
        <property type="entry name" value="N-ACETYLTRANSFERASE 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="14"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1899654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="253" mass="27638" checksum="E63763C82825BD6D" modified="2025-10-08" version="1">MKVNEGIAVSTSKILLVPYEARHVPLYHQWMTDPKIQEATASEPLSFGEELENQKSWRTSIDKLTFILCQPSVSASGSPVSSAIIPGNADSSANMLGDINLFLTEVILSDSDDEGATVPGSGSCCTGGGNGCHSHNNPDEERLYTGEIDVMVATSIQQGKGNGTAAVRTMLHYISQNEARIVAEASQGGEGKIMSLEARIKENNDRSRRLFSRLGFVQRGAVNYFGEIKMVCDRSWRDIRVDGYKEVPYMREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHR7</accession>
    <name>A0ABR3ZHR7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_001231</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000018">
        <property type="protein sequence ID" value="KAL1899732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="240"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="369" mass="42472" checksum="A559EC90C324A8B3" modified="2025-10-08" version="1">MCRKSDVLKKGKTRGWELMLSYNLSTHITSGYFKTTPSAKPGQIMDLLKTETTAATLAHPFLLPMLVLSLNELSSENDDRQRQARELLRHLENAIAGREDAEIKADHLKDGSLIIEQVNRDLYECVCKVLWKRPRAYLSMLTELRKGLVRWWMVIEPEVKKNEDVKDLQENMLSKVDFHAIKLRGIDSYAATSLERLRVQREALYNIIAQRESKLSLIMAREQSIIANASKRDGTTMKTLSVLGAIFLPGTYLASVFSMTFFNFQDSGVPKVSKDVWVYFAITIPVTIFVVAIWHFFEACRKRDHEEQEQRVNEEWDKMEHAVMEKIRSKTIKHQQTTMSSTPAWKQGGKEMDIERQGGMEMLEKVLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHV1</accession>
    <name>A0ABR3ZHV1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">37S ribosomal protein SWS2 mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_001434</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000022">
        <property type="protein sequence ID" value="KAL1899398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="entry name" value="30s ribosomal protein s13, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="Rbsml_uS13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_uS13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_uS13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018269">
        <property type="entry name" value="Ribosomal_uS13_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S13/40S RIBOSOMAL PROTEIN S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US13M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002134">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="S13-like H2TH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00646">
        <property type="entry name" value="RIBOSOMAL_S13_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1899398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="115" mass="13041" checksum="4F5BE67EF870389E" modified="2025-10-08" version="1">MSVNFTENKLVNKVLTSFYALGPTTASRLMSKYSIHPLAKIGSLSAKNVTSLTAELSQMTIENDAKRQLREGIQRLKDMGSYRGRRHAMGLPVRGQRTRNQIFNAKKFNRLDRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI51</accession>
    <name>A0ABR3ZI51_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ferrochelatase</fullName>
            <ecNumber evidence="7">4.98.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">HEM15</name>
        <name evidence="8" type="ORF">Cpir12675_001020</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the ferrous insertion into protoporphyrin IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>heme b + 2 H(+) = protoporphyrin IX + Fe(2+)</text>
            <dbReference type="Rhea" id="RHEA:22584"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="4.98.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Porphyrin-containing compound metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ferrochelatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.98.1.1" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000014">
        <property type="protein sequence ID" value="KAL1900336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00419">
        <property type="entry name" value="Ferrochelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03411">
        <property type="entry name" value="Ferrochelatase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1400">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00323">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001015">
        <property type="entry name" value="Ferrochelatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019772">
        <property type="entry name" value="Ferrochelatase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033644">
        <property type="entry name" value="Ferrochelatase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033659">
        <property type="entry name" value="Ferrochelatase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00109">
        <property type="entry name" value="hemH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11108">
        <property type="entry name" value="FERROCHELATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11108:SF1">
        <property type="entry name" value="FERROCHELATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00762">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53800">
        <property type="entry name" value="Chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00534">
        <property type="entry name" value="FERROCHELATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="3 7" id="KW-0408">Iron</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6 7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="421" mass="47054" checksum="49409A2EEDB2A154" modified="2025-10-08" version="1">MATRSSLRLSHSLSQRLASPIAVSPMAGRRYLKTQVSPVTQSKIGSKGPTAMVFLNMGGPSTLNDVGDFLSRLFADGDLIPLGRLQNYLGPLISKRRTPKIKKQYDEIGGGSPIRKWSEYQAEEMCKLLDQMCPETAPHKPYVAFRYAAPLTEEMYQKLFDDGFGRGKGGRAVAFTQYPQYSCSTTGSSLNELWKWRQKLEAKGPDGKPVDSEGSIQWSVIDRWPAHSGLVEAFAQNIEQKLLEYPEERRKDVVILFSAHSLPMTVVNRGDPYPAEVAATVYAVMERLKFSNPYRLCWQSQVGPQPWLGPQTSTSVEEYVKRGQTDMVLVPIAFTSDHIETLYELDKEVIGESGHEDTIKRVESLNGSPVFIKALADIALEHLKHGSSTSAQLQLRCPGCTNLKCVESKRFYQEQEKALQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIS1</accession>
    <name>A0ABR3ZIS1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UvrD-like helicase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001004</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000014">
        <property type="protein sequence ID" value="KAL1900320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17932">
        <property type="entry name" value="DEXQc_UvrD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027785">
        <property type="entry name" value="UvrD-like_helicase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070:SF66">
        <property type="entry name" value="UVRD-LIKE HELICASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13245">
        <property type="entry name" value="AAA_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13538">
        <property type="entry name" value="UvrD_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="2">
        <location>
            <begin position="466"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="795"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="795"/>
            <end position="809"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="979" mass="109798" checksum="1D85935F30A09584" modified="2025-10-08" version="1">MRQAFVRGQSTPPSLRPVWPVYNQKSSPVPRIRHFSIATKSASLRKLLRQILPSSSLTRTPPSLSQWKADNSRGWHSIYNMEASSEESDRLALSPSARLQQSRSQSSTRSPSPANSTAPSTPITPSTTSGATSFVSAATIRNGETKVENHSPSPPKRRRKKGQFVPSEEQKRIVELSKDHNVLVSARPGSGKTSTAEALVADAGPDERIAILTYSRRLCVETKKRLEKYSSSCSVLTFHAMACRLFGSSLHTDAQLLAELKRLNHGECKPLRWSGRPYDIIVLDEFQDCTPLLFWLVCIFIRVNNRALGKSARLVILGDDKQAIYGFRKADARFLNFAPDLLGPLSPEYPWAKQTLSKSFRLSHQTVDFINTVYLKGQKYMRGSKSGPMPIFLNANIFKPGPIAAKLMSLINKYRAENTAILAPSVRGSQIMSGLVNILAEEYGVPIAVSTNDDVPLDERVIKGKVSAATIHQFKGSERDLVILLGVSNHSYFNFIARDAPDDHCTNQIFVGLTRAREQLVVVNYSKEPLLSFLSVDDIPDKAIWDKTRDIPVTENELIHGPKPGRPAQNGLLLNSTSSVIDVVRFIPDEELQALIDRYLDIQTISPALPENEQINLPVIIPTKWNIQKPREDKSDKSSEDQFYPQDDWNFHEAVSDLNGLAVVAVCEHKMLGTLTTLIPPNEASNDNTDLKVLNSWLGGNLTKENVHWLCQKACEYESKRSKFKPRFLQMQTQECDWITPEDLAAARTRLNEELANSPYGKGLAFEVSFRHEYTIDNETTQFIGMADIIGVKADPKKEESKKDSKKSDTTTNPLHSANTSRKHSACLWEIKFVSTLTNEHILQTILYAQLFTIEHKCLPEVIILFNVRTGEKLQIKMKVRADGTSPEKLLAKFTEQVFRLKFVTAAISEDDEFIMDNLMTREEAIAVVDRPGVALVKDEKKVYKDEVIQAWKDNQGITFEQDDSNDVAHLKNKENNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK10</accession>
    <name>A0ABR3ZK10_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_000768</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="82"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="110"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="156"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="205"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="294"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="333"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1086"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="294"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1095"/>
            <end position="1104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1900755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1156" mass="129098" checksum="6221B9C9E85BC6B0" modified="2025-10-08" version="1">MINTVLPKSSVEFPSVSHDSVPAASLRGYSAPAPTTSDTTNAFSTTVAASPTPPTSFTLSPGRRSTTRSKTDSRAPASSRPHVCPDCQRQYSRSEHLARHIQSHTLGKRFQCSDCGKAFARTDLLRRHAQSHKNEDGSKRRRIGAGAPRAGRVSHACKQCSTARVKCEETKPCTHCRLRNLICEYNANEAALALYNPHLKASAPGGLTTTASSSLRRPLKGGCEGEIEESISEPAPRSMPELIYGSKSTLKLGTQASPSVSPMQALDGLENPSVRLLPIPVETLETPITIANFQQQAQQQPQKQVKQQQQQPPAQPPDSVLFQLRQPEMPFSSMNIPGSDFYCPEASNNDNTREIPGAQVTSPESRLEYQRAHPTQQSQSGVLTQSAQDFQSQAMAALVLPSSTMIMPQSNVPPDEITLMPISSCQMDVTQEMPQFCISQSISDIEHMSFSDFLRDVIYESQMEMHNAIGSSVFPTLDFYGDANLDLGATDYGLINSLNVDKELVSKNENSCVQEEGLNLIKFRHELNFLWSCDFSGNCSDPGHSCWGEDPSQLEQKCQDSNSLLIVEESRKKLCSIFTDKISPKCRDAVVSLLSQGHKMQDTFEKMSTSFPSLEALDGFAYIYLSESLQSLSNFIHFPTLKFSSQSPHWIASIIAYGAVLIPLPTARRFGFAVQESVRISNRILVESKINKSLDLDLFQATVILQDLAMWSGNRATMSTADSHIAFPVSILRYQRKYQRLSYPIILVHPDDYGKVLESKWRQWSQQESWKRLVYHSVIKDAEVSTMATTTPRVSYEELNLPLPESKDLWLAKTATEWKELYLKCWSGQTSKLPSAVDLLKDVSLLTNYLGRLDIQLSVSIYLSGSATLSHQYHQLCGIQCSRPFVTRNLAGRSHNLLNERHQELCKELRDFQQLSFQWGPQNALLVQQNVMLHLQLMQLHISINDVYLFTGREGEDQIRNSYVILRQWTRSTEAREALWHAGQTLRYAKMLPPGTMKDFWCITVVQAGLAFWVYGIITKASKKPQENHSDSNSAAHLEDGDMRLRDNFVPHIPGCYVNEPLFLDGENNTAVMRYLSMGQGQPFIRGPAPRNPSGGDSNSNAMLQASPEDPRACIGLLYNIMMDNFGWDIGRVPLLVHNMVNFMKRLSAIAARVHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKE5</accession>
    <name>A0ABR3ZKE5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_000846</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050331">
        <property type="entry name" value="Zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515">
        <property type="entry name" value="PR DOMAIN ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515:SF58">
        <property type="entry name" value="ZINC FINGER PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="896"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="922"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="98"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="560"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="622"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="677"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="145"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="159"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="222"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="575"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="636"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="677"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="690"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="708"/>
            <end position="724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1006" mass="108262" checksum="56589D0A14D6E591" modified="2025-10-08" version="1">MAPPSPLPDLVKRKTSDLLQEAMNLHSRTTSTTMDSSAILPSTRCLKTLDRRDLSKGGVAGVSIGSVVGLSIVFFIAYPFVARSVRLGWNRWKAKRKVIRDKHQDSSKSDASQDAENNEPETTRDSSTQQELGASLQQPLSRQVSFSSSLDHSSGDESPASQTRALSDISNPEEPNPDGNIGSEPPEYINFTTGLSSTYYSSDVPNSAFGLSNDAEMQDPDEFQKAQDRASTEPENRKSSTLISTIRKIAQGISGSTSDNSVTNSASRALGDTRVIDRNITESPTNLGTDSAAISGKNSTIGDRGFVLPPDVVYRKHPRMDAANTPAPVPTTALETVNPMEIMGMGTLTENERTWRFTHLGTDPQSNADEEVVQALLDAAYANGVELNLSELASGMGAVDTTGANAGAGAATGEPSCNNSGLSSNLSVKGAQNVDALLDHGMSGSTVAPEHSGSLQPTATKANFSIPSTTAGVTDTGSAAVHQMHLGIVDSVASHSYNSHTPAHRHTPLGYSHSDLVGTEAPLPTAGNFASTFELPRHDVAVSPAITPSSVNAFPSPISMTTAASQDGPYEDSFNTNSTSNINTNTNTNTQSGIHIHTDTSSSTIAQLQPHFNLATAPLSALTTNDHHSSPQQSRLAPQAQQVQLPPQLQEQQQLSASQISQLQQEAINLDSSNTLQQTARHPQLSVPNQSQPWNQQQQRQQQQQQQISGSPGTQNLIPNSNISGFLPSPPQPTENQFMDASYSSLYPQPQASYANPGSYSAFMDMNNSAMMSEDMLYQRRVNIPYDQAPQIMAANVSNMPMDSMNVDIDLVEYLPSQPPQYAAHSYTLSNASAEYGADVSDMSTPYHFNSPSAHSVANTPDTRISVTPSPKVNLMHDITSPYTAICQSSPISTALKCDECGRTFNQAHKLNHHKRYHERPHECVHDGCGKSFGTKTHLERHVNDKHKQTRKYHCTEPGCAYSRASGKGFPRKDNWRRHMLNIHGCSPGASIQADVVDESMMNTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKN9</accession>
    <name>A0ABR3ZKN9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein UsgS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000806</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38421:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38421">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN USGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="304"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="383" mass="43478" checksum="5EF42312CEFE50EE" modified="2025-10-08" version="1">MADTAFLDKAKLKRQLDVTDGQGHLDKDKLKAKFGASNFDLNAFVRGAQVALVGANRAMQNPAIFNNQHYKQAAIAVVVGVAIHIIVLIPSYGIRIMLWFVSWFISLDTVSWDDWITNGLDFIQKSVLQVPFLVMSLMRFITPTLDNLFMDSLRWVDTTYVRMHQHDDPSHLRPMYYPNLKQYSTRDSRTHNMRTADSFTQTLVRHARKAALGLAIYAASFLPVVGRFVLPALSFYTFRKAVGLGPATALFAFGLVLPRSWGVVFLQTYYGSRSLVRELLEPYFARVRFDARQKRKWFRAREGILFGFGLGFWVLARVPLVGVLMYGIAEASAAYLVTKITDAPPLPRDATGFAESQQEWRNKQKFLSMPMAKLDTFLDKVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL14</accession>
    <name>A0ABR3ZL14_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Carnitine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">CRC1</name>
        <name evidence="13" type="ORF">Cpir12675_000619</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000008">
        <property type="protein sequence ID" value="KAL1901130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF4">
        <property type="entry name" value="CONGESTED-LIKE TRACHEA PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="20"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="119"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="226"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1901130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="314" mass="32619" checksum="A6A5DE9FCF892B5E" modified="2025-10-08" version="1">MTASSNKEPSAAAPAESALLAQVRSFVAGGFGGVCAVVIGHPFDLVKVRLQTAERGVYSGAIDVVKKGVAKDGLRRGLYAGVSAPLVGVTPMFAVSFWGYDLGKDLIRHALPSNTDGSLTIAQISAAGFFSAVPMTAITAPFERVKVILQVQGQRTLAPGEKPKYSGGLDVVRQLYREGGLRSVFRGSAATLARDGPGSAAYFATYEIIKRRLTPTDSAGKPTGDLSLGAITVAGAAAGVAMWVPVFPIDTVKSRLQTAEGNATISSVVRELFAKGGYKAFFPGFGPALARAVPANAATFLGVELAHQAMNKIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLZ6</accession>
    <name>A0ABR3ZLZ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Casein kinase II subunit beta</fullName>
            <shortName evidence="3">CK II beta</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RIC1_2</name>
        <name evidence="5" type="ORF">Cpir12675_000251</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 3">Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the casein kinase 2 subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1820.10">
        <property type="entry name" value="protein kinase ck2 holoenzyme, chain C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016149">
        <property type="entry name" value="Casein_kin_II_reg-sub_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035991">
        <property type="entry name" value="Casein_kinase_II_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000704">
        <property type="entry name" value="Casein_kinase_II_reg-sub"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11740">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11740:SF39">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01214">
        <property type="entry name" value="CK_II_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00472">
        <property type="entry name" value="CASNKINASEII"/>
    </dbReference>
    <dbReference type="SMART" id="SM01085">
        <property type="entry name" value="CK_II_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57798">
        <property type="entry name" value="Casein kinase II beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01101">
        <property type="entry name" value="CK2_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="222"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00045899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1901743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="263" mass="30681" checksum="FD4CFBFA4813CAE1" modified="2025-10-08" version="1">MMDDFGSDSDSEYTSYWRDWFISMRGHEYFCEVDEEYLTDRFNLTGLNSEVQYYQYAMDLITDMFELECDDDMRDAIEKSARQLYGLVHARFIVTTRGLGKMLEKYKRSDFGKCPRIMCEGQPLLPMGLADIPGQKPVKLYCARCEDIYNPKSSRHASLDGAFFGTSFHNIFFQVYPPLMPIKSTERYVPRVYGFKVHSAAALIRWQEEQRDELRRRLKVAGVETGFDEDDEDCEEEEGDEDEEEDRMELAEIQGQIPVPSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM45</accession>
    <name>A0ABR3ZM45_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF2066 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046263572" description="DUF2066 domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="245" mass="28158" checksum="392F82E8AA41B88A" modified="2025-10-08" version="1">MKFSLYSLSLGFYLFGSAQADILNDKEYDVLEPQPQKYMVFSPELDTSNSQLSMLFFYPEEKVSTVIAAKNDEEAVDDPELSFTEIYNALLKRAKMTSDEIRWLIFDVDKDEEISQLSLNIRQERGLDPKAQVEILPNEEEWKIIMQSEYYMQAVLIIGKQADRIVLRVQESPEWWENIYPSGRIQFFFSPPDNEISTSGDDGETYWLSGDEESALFSRMEEQEAAIWAETFSEAVGGTLTDLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN91</accession>
    <name>A0ABR3ZN91_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Slx4p interacting protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SLX1</name>
        <name evidence="11" type="ORF">Cpir12675_000309</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="8">Forms a heterodimer with SLX4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the SLX1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10455">
        <property type="entry name" value="GIY-YIG_SLX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="entry name" value="GIY-YIG endonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03100">
        <property type="entry name" value="Endonuc_su_Slx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027520">
        <property type="entry name" value="Slx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048749">
        <property type="entry name" value="SLX1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050381">
        <property type="entry name" value="SLX1_endonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20208">
        <property type="entry name" value="STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20208:SF10">
        <property type="entry name" value="STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21202">
        <property type="entry name" value="SLX1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 8" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2 8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="10">
        <location>
            <begin position="10"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="25"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1901619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="367" mass="40551" checksum="5F30598398027763" modified="2025-10-08" version="1">MTVQTKPIPPNYCVYVLRSSIKPKTAQPYVGSTPNPERRLNQHNGLTKGGASRTARKELRPWEMVFIVSGFPSMIGALKFEWALANPHISSHIPEDERISVSKARKRNGMPKRPRDKIPSVLANVHLLLRSPSFSRWPLTVNVFEPEVYTIWQKCCSEVAVPLRPSLKIRTDFSAPMAPAVLAGEGADASLELSNLESEKEESDDDNAPTAEEVPKTGIKSIPIDYKPLKDYAEKTRSIFEFERQGYCVFCRGNMKNGEGLYVVCSGVGCEAVGHLDCWAKHGLSSTSKPTNSGEHIAMIPIEAQCPGCGKVASWGELMKELSLRVRGAKEVDKLLKKRRPAKAKVKTKQIAEEEVAAAVEVEEVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNF1</accession>
    <name>A0ABR3ZNF1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Histone H4-like TAF Taf6, SAGA complex subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">taf6</name>
        <name evidence="7" type="ORF">Cpir12675_000306</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22931">
        <property type="entry name" value="HFD_TAF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08050">
        <property type="entry name" value="TAF6C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.770">
        <property type="entry name" value="TAF6, C-terminal HEAT repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037796">
        <property type="entry name" value="TAF6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011442">
        <property type="entry name" value="TAF6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046344">
        <property type="entry name" value="TAF6_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004823">
        <property type="entry name" value="TAF_TATA-bd_Histone-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10221">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10221:SF9">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02969">
        <property type="entry name" value="TAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07571">
        <property type="entry name" value="TAF6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00803">
        <property type="entry name" value="TAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TATA box binding protein associated factor (TAF) histone-like fold" evidence="6">
        <location>
            <begin position="9"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="462" mass="50719" checksum="EC480726EAEBF506" modified="2025-10-08" version="1">MASDEPKLLWNPENVRDVAESVGISNIGEEALRTLTQDTEYRLGQVTVEALRFMRACGRTALTVNDVSMALKVLDVEPLYGYDSTRPLRYGEASLGPGQPLYYIEDEEVDFEKLINAPLPKVPRDIMFTAHWLAIEGVQPAIPQNPVFSESRSHELVPKGTGANPALSALAGNDGAPLKPSVKHVISKEMVLYFDKIQAAVLDETPDEEVERLRQAALASVRDDPGLHQLVPYFVNYIANQVTHRLDDLFVLRQMMELTSALISNTSLFLDPYASPISSPVLTCLMARKLGADDSPESTRTQYQLREFAASLVGKLAARYATSNHLLRPKLTRTCLKYFLDPSKPVPVLYGAILGLAAAGGPESIRILVVKTLKDFDAAVLMPLKEKGTERSLDYEMLLGAIVQAVSSVSGSEIIVESNGVNGTGSEGIDMVEFLGKNIGERILQIGNHRLNKLVLDARYIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNI8</accession>
    <name>A0ABR3ZNI8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="46"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="643" mass="72996" checksum="23268AD60A35092F" modified="2025-10-08" version="1">MSGPASASSMLSVKALCSPDPTSAPPSSEAFLASVTSPDPASALSRDLINGLPDEVLLMIFQAFYTSDHAGESVRLRLVCRKWNAFTRSQVCTALKINYEDFAYLHELAFDRRIWESLGRVQHLCRNLYINLKLLKHKCDHDKFKNFSHPDPKVLQEVHEMKLRYFPVDYEDERYPKRKGSALSANSINAVLKKILTHSLALSRCRVDLPQSLARMEYDDETHIATFALGNILLYLARCIRYHRRQSTDDNAEPDDKGRLLHKANIVTDSLEEENIHSDDEDKVTGNDPSEVKLETLIITSMFETVLHRLWRNPMDHKNMRTVMRNLKHLDMEISLIYQPNASHTVLWPLMKYAPGLESLCLSQIFRHGMEVEPSHMLYTIPETRELWASRALPNPCVTLENLTSLELRHVNIFPSFFTNAVAAFGSSLKELYLDTVTLFIEDEDLPDSGILCNSRIPKQRWIGFPGVRPQKDYIWVAMFLRENMPHLERCRASNLDCCFFGIGHSNLGDGAAPNSVFSEFHQDLGIAAGRTISQIFSEVVNGIEQPLIAKDSGFEGRHVFLPYSADNDERILGNLKPRPQNGDIPPQEYDHDSYIGSGGVTPSYWSRKSLDGVFPNSTGGTANMAWERMMHLLSNKSNYNYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPD5</accession>
    <name>A0ABR3ZPD5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dynactin subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_000004</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027777">
        <property type="entry name" value="DCTN6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13072">
        <property type="entry name" value="DYNACTIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13072:SF0">
        <property type="entry name" value="DYNACTIN SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1902107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="194" mass="20603" checksum="CBE1F1B6DA8E2620" modified="2025-10-08" version="1">MSKRHSIVPPAGRDGPRPPTKLSSSLVIADTAILVGTHNIVIMSESVVHPRCRLDSTSGGVFIGSRCIIQERVHLGARSHGVQHVSDGNVMIGDYVTIEATAVIETGDTQIGEGSVIGIGARIGGGASIGKNCTIAPHVLIPPGAEIPASTVVYGNNLKMRCDQRDIIELKRKAQMRQIDVLRKMIASNPAKFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPL9</accession>
    <name>A0ABR3ZPL9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_000097</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028143">
        <property type="entry name" value="Get2/sif1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28263">
        <property type="entry name" value="GOLGI TO ER TRAFFIC PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28263:SF1">
        <property type="entry name" value="GOLGI TO ER TRAFFIC PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08690">
        <property type="entry name" value="GET2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="42"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="54"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="346" mass="35809" checksum="8C853544055E6263" modified="2025-10-08" version="1">MDSPEAEAQAAAARAAEQTRIRKERRAAKILAGGSHRLNKITGLSGRKAETELPAPADTVTVDATTSTVPPAPTAASSADATSEDPAEVDISNHCYEPTRTTRPPVSTYGPSSAAAFAAEDAPSTISEAQLRSLMLGMDPANASGGRPSAPTANSAPAELGEGDPFAMLQQMMGGAGASAGIGGMFPGGIQPTESVPTSRSAAIFRVMHVLFALSLGIFIAFKTPFTGSLSQRLDPSFDFAALSSVSSPDATTDDHHTAFAGRSPSDLLWVFATGEAVLLSARYFVEKNSPSAGVVGILGTILSFIPPPLGGYIKLAMRYGQFCMAVRNDIMLSVFVLGVCAWVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPN5</accession>
    <name>A0ABR3ZPN5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000014</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19327">
        <property type="entry name" value="GOLGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19327:SF0">
        <property type="entry name" value="GOLGIN SUBFAMILY A MEMBER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="412"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="601"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="643"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="15"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="64"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="111"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="136"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="153"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="169"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="230"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="414"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="608"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="994" mass="105349" checksum="84388F2B3D6B1218" modified="2025-10-08" version="1">MSDVEAAETTKPEAAKPVSASPVPTPTLTPSSIPTSPVSKASGTSSTSTTPKPELRKASATTTSAVRRPVASASSAKTATSATAAASSRAAGGLAKPPTRPSASSTVRRPAASSTMASHRSSASVSASEDEKKRPSSLTSTAARRQSSINPGTAIPASPARASAERRTSSIASSAATSTRKPLSSTSGSTSTARTTTTSSRPSTVSTRTPSVSRQSLSATSSDAPKKRLSSVGSLSSSTTTSTTSRLVNRSVTPGSAASSKELEVLKTKLSEKEAEIEGLKSQVQSGQDKIVELGDQIEKEKGATNTEAISEDNAKQLEELKTHHQLQVGELEAKCTSSAELLSAAQLELAELKTAVSEALAAKEALESKVSSLEDDIAKAAEQATTESASKIAEFESRHEAAIAELKSKQATEMDSLNSSSNDQTNALSELKSAHESELSALQAKINSLSEELVSHKTAAESTAAEADITRTDVESRLAAAQSDLAAKVAELDQATSELAAAKVSVAELTSELDAVKAELENAKEQAAKIDEEHKLALLNVTDKFEAEIKTLRDDAVFKGKFQELESKHDELVKSHTETIEDHQAATEANEATLDALKTQHAEELSKASSSASTASDELSTKLEELKTTHAAEIDALKASQAEALETAKAANTSELQAANEAHAVELAKVQESGNIENAAQIAILEKEIDELKSQILSHQAAAKKKEDEQQNEITSLISDHQKELVQKQASLDTAEQRATELTQSLNAQQDESRKQQAEHTNAIATVKGESDQAAAALKKELEELAERSKAQAAEATEKAKALEEQIEALKNIPDELVQAKAALEKANLELDELGQKLILEKMEKANALADLDSAQNGSKSGSAELEAARKELATLRETAEGQQKELSNLKEELQLAQKEVETRKLEADATIKTAKADYEDMHHTLTELVEMEQKKKEEAEGKATTLQKKLQDAEETMAKVAEKEKLFDELQAQLKVKDAEIAEAKVQLSKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YCM2</accession>
    <name>A0ABR3YCM2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">E2 ubiquitin-protein ligase peroxin 4</fullName>
            <ecNumber evidence="3">2.3.2.23</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PEX4</name>
        <name evidence="3" type="ORF">Cpir12675_006887</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000405">
        <property type="protein sequence ID" value="KAL1886056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23812">
        <property type="entry name" value="UBCc_ScPEX4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="2">
        <location>
            <begin position="8"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1886056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="166" mass="18190" checksum="AD9547274F2CAB78" modified="2025-10-08" version="1">MAGRGALKFAKRLMKEIEALRSEDLNGAGIERLGPKSDDDLSNWEAVLSGRGVGHGYDEGRWLLSIEVPPQYPLQPPKVTFITQIVHPNVAIPSGEICLDLLKDAWTPQYTLVEVIKAIRMLLADPGTDSPLNVDVAALIREGDAVAARGLVRLWCRQPEGYYSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YDK2</accession>
    <name>A0ABR3YDK2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Protein mpe1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">MPE1</name>
        <name evidence="10" type="ORF">Cpir12675_006896</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000409">
        <property type="protein sequence ID" value="KAL1886046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16620">
        <property type="entry name" value="vRING-HC-C4C4_RBBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014891">
        <property type="entry name" value="DWNN_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033489">
        <property type="entry name" value="RBBP6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025829">
        <property type="entry name" value="Zn_knuckle_CX2CX3GHX4C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15439:SF0">
        <property type="entry name" value="CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15439">
        <property type="entry name" value="RETINOBLASTOMA-BINDING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08783">
        <property type="entry name" value="DWNN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13696">
        <property type="entry name" value="zf-CCHC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01180">
        <property type="entry name" value="DWNN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51282">
        <property type="entry name" value="DWNN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DWNN" evidence="9">
        <location>
            <begin position="5"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="8">
        <location>
            <begin position="183"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="387"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="691"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="401"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="441"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1886046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="727" mass="78341" checksum="2E449BA4CDA1B353" modified="2025-10-08" version="1">MSSSVFFKFKSQKEPTRVEFDGTGISVFELKREIITKSGLGDGTDFDLAIYTDDNAEEYDDDTTIIPRSTTVVARRLPPIRPGAGRAARYISGKMPINARFRNNAQKPGAPVRPSAGPAPAPVMEINENMTEEEKMKAMFAAQSAQWTVQKEEMAHQQPVYVKPTNKRVANVPDHEPPNGYVCYRCSEKGHWIQQCPTNDDPEFDNRPRVKRTTGIPRSFLTTVDKSVVLAKSGDDEEGKRPAGVMVNADGDYVIARPDKVSWERFQAKAKTSAEASKLETSGNKDLQERGLECSIDKKMFVEPTKTPCCGKTFCNDCITNALMFSDFVCPACQADNVLIDDLKPDEDMVAKIKEYIETRATRAPSAAPDSPSNASITAGVIGTTIEPAKSEKSQDVGATDVSSSAQGTPQPEDNGSSSANGSVKAPSPEPANGTCEESPTAAITSTATDTTSSSNATTISTTVVAPKGPGSTGSNDSQKRKRPVDELQQNPRIPKAPRAMQMQQQRQAMNNVFPVGMPNMPNMPMMPFMMNMPNMMGPGAMNMTPMGPNVMGMMGMNMGMGSMGGPMGMGNMDGGSMGNMGNMNNMNNMNNMNNMNNMGNMGSMGGPHGNFNNGFNAGRNGVNQNNWNANNRGFNNNFNNSRGGGHNNWAGGPNANGFNVGPNAPSMGMNMGGMGMGMGMGMGNMQAAAGMGGMQPDEDAYFRKPLNPNRHQNRGRRVRPSDYREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFY1</accession>
    <name>A0ABR3YFY1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_006677</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000348">
        <property type="protein sequence ID" value="KAL1887147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="112"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="436"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="436"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="471"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="510"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="533"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1887147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="573" mass="62146" checksum="7414620886E0721B" modified="2025-10-08" version="1" fragment="single">LGPEFAAECEQVVSKAFPANIVFHKPTFVQQIKNYSTDLSIAYGMMSCAARSSSALVRRYGGSLGATGAAEHFAQKAIARINETMDSPSLADIQAMCLVVIHEWGSRNAVRAYIYLGQAARMLQMYRILNSHQHQPDGDRFLREESFRRTLWLVYVLDCILSSTPGRYPALSAADIVGVALPCTDVNYAFGNAVYVKTIALEDPVGMPAGAPTDDIGEFGHIVLATRIWRNVVHCLTLSSVSNFNEDDLYSLMGEVDRLRASLPMQYVDKPGQISLHITMGSGTTYAMIHCILHCATIFIHRRRLLQYVSLGMDNWRKMSQCHEIIDRLMTSCHTITSMLMALEISSDKDSILNFPIFMLFATFTASSTVAYLSLKGLTPPSAVETAATIVKDGLHLMDTSVDIWPLISSWSRHLAVMQRVLNNDAAAAARNAATTGSNNLTVPHIQRNSPSVKDDAASNADTNPDAMDYDQNQVVNSDTARGDSEPPMRRTGGIATINGGTSGVPTPGRGSSPNAETNVDRQPTPNSEVKSEAPAPNPASASMDMTSAELCAAFEKQLLELDDLAALMGGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG57</accession>
    <name>A0ABR3YG57_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Choline transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_006754</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000367">
        <property type="protein sequence ID" value="KAL1887015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF23">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="258"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="303"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="400"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="426"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="462"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="501"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1887015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="534" mass="57483" checksum="0E91B048CE151E89" modified="2025-10-08" version="1">MSSNQIVPQDLGAGLVGKSDWKKDSPEDGIISSPEGSEAAADHALEDLGYKPELTRNRSTWQVAFMSFVLASIPYGLATTMFYPLINGGPVNIIWGWVAVSLIILCVAASLGEITSVYPTAGGVYYQSFMLAPPSWRRLAAWTTGWLYLVGNVTITLAVNFGTTLFYVACINVFTDSEGNDIFPASKYQTFLIFLAITIFCNLVSSLCNKYLPWLDTAAIYWTFAGVIAIAICVLVLAKEGRHSSKYVFTHFETNSGWVPGWSFCVGLLHAGYATSSTGMVISMCEEVHNPAVQVPRAMVTTIFFNTIAGLLFLIPMVYVLPDIATLISLPSGQPVPTIIKSAVGSAGGAFGLLIPIMVLALICGIGCTTATSRCVWAFARDGAIPGSRWWKEINHKLDVPLNAMILSMIVQVVLGAIYFGSSAAFNAFSGVGVVCLTSSYATPIAISLWNGRSHLKNAKFPLGRGLGIFCNVVSLAWSALALPLFCMPSYLPVTASTVNYAPAVFVGAMGISALWYIVWGRKNYTGPPTHEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGH0</accession>
    <name>A0ABR3YGH0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006822</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000385">
        <property type="protein sequence ID" value="KAL1886947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1886947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="272" mass="29658" checksum="609380223EEFDBA5" modified="2025-10-08" version="1">MHSPQSVWLPFAFGFSDGPSSRQQRARASDSQSTTSPDYPTLPSSDRRASSHPYVAAPAPTMPSSRRLTRRFTGSENPELQLPQMSEPARARGPRVSSSQQTDIALILAGKFEQNEFSMLLVILILSSTVVFCHSLIRAYVLITRPVQHPASDPLYNVHGYAIPAEPIPVILARDEEAAGIESETTKLSPPAYGLWRSSVRVDPDGLRWQPNPNATSQEPDGPRVEPRPPSYASDDGITYVVDAVPRSTVPSEDSSLPLHPSEAGRVNPSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGV9</accession>
    <name>A0ABR3YGV9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Increased recombination centers protein 22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">IRC22</name>
        <name evidence="12" type="ORF">Cpir12675_006721</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Is probably involved in a pathway contributing to genomic integrity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the IRC22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000359">
        <property type="protein sequence ID" value="KAL1887053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005595">
        <property type="entry name" value="TRAP_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12924:SF0">
        <property type="entry name" value="TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12924">
        <property type="entry name" value="TRANSLOCON-ASSOCIATED PROTEIN, ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03896">
        <property type="entry name" value="TRAP_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0732">Signal</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046185391" evidence="11">
        <location>
            <begin position="21"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="218"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1887053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="260" mass="27592" checksum="FF50149C23A649CA" modified="2025-10-08" version="1">MLFKPSLLAALALTVFGVAAQDSATPNTSDEAPNAELPPLPAKVTTSFPNSDATLGLKLVNGNPTVARIELENQAEEAVQLAFVGGRIAKPTTPDTIMVNLTTTPYGESIPAGETKVVEYAFELDMNAQEVLLNLVAVVADSQGQIYQVMAYNNTASIVEPPVSLLDPQILFLYLILMGTFGGIGYFVYSTWVEPLLAPPASKRPQKAKKAVPVVVEPTSGDESGAANASGYDESWIPNHHINKPISKRVKGGAKGKKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGX7</accession>
    <name>A0ABR3YGX7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006697</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000355">
        <property type="protein sequence ID" value="KAL1887092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046342747" description="EGF-like domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="188" mass="20490" checksum="67F0C4B5D8F11F17" modified="2025-10-08" version="1">MQLIHAIVAFVAASQATAIASNANLTPRSNIAEAANMKYTRDVEECKANCDSRLARRADASNAKSDCHEKCASDNQGEASKAKRGDDDDEKENEEEKEAQCFDQCSPYPGQNMCHESASCIYVTSGNPKFYCGCASGFKPEDVSPENAFRLPWLGQEGRVFVKPGVSCQKVCDNILTCAEVDVQPKCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH38</accession>
    <name>A0ABR3YH38_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chromatin structure-remodeling complex protein rsc9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RSC9</name>
        <name evidence="8" type="ORF">Cpir12675_006701</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000356">
        <property type="protein sequence ID" value="KAL1887081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16100">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.60">
        <property type="entry name" value="ARID DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001606">
        <property type="entry name" value="ARID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036431">
        <property type="entry name" value="ARID_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052406">
        <property type="entry name" value="Chromatin_Remodeling_Comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003150">
        <property type="entry name" value="DNA-bd_RFX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22970">
        <property type="entry name" value="AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22970:SF14">
        <property type="entry name" value="AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01388">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01014">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00501">
        <property type="entry name" value="BRIGHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46774">
        <property type="entry name" value="ARID-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51011">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51526">
        <property type="entry name" value="RFX_DBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="ARID" evidence="6">
        <location>
            <begin position="15"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="RFX-type winged-helix" evidence="7">
        <location>
            <begin position="649"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="159"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="829"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="190"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1887081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="991" mass="111113" checksum="4F33E21DF458E127" modified="2025-10-08" version="1">MTSTGEIELHRIDRTLEYVEFIEKVRSYHNERGTNFDSEPRVGNIHLDLFKVFKHVVANGGYDKISDEKLAWRRIANELGIISSNEASTAFALKEKFYKNLAAYEIKFVHNQEPPPKDILEDVTAKGAGLLTRTRENYRGYKRESTMGFEPAVDLNSPARASAASNTPLSARASRGLRETPAQRVIFQPDTGTSRQSRTAPRQHAPMGHGTPTPGNHHLHQQMHQNLGHPHPMHGHAGVAQPHMIPQQPRIPRNHGIYNEKLDLVDAPTEPYDPKITLTINVKPVDTPGNNHAEFLRRRQADRLFAAGGPRPPFQPGRGYEGPNIYLRCLYALRSGLKDEQTYALNHLVKISYERGDKYKFESFPGLVEGLVQKALEVGSYFYNVNWKINWVSGPTNTDIGALDGLQNCPDILDRIAKLTPKDVQDEIQPAEFSDGLTLSNEALLTLRNMVTLPENAHYLSEYAPARDLLCVILNLPNLESTVELKHAALDIAEQITPFLILPSTDPLYISLLSQMTSNDRGVILSSLRALGRISMNLEAANTLGNVPIEVLERIYQYVLLGDEELIDAGLDFLYQYTAVVSNVEKLVRGDFTIQLITYLVLLLSHGAKHFTNEFVIEAEKTLPAPLEIATLPADLLDKFMAIEEPERVHRWIQCCFEEDVQSHITQLSAWQAYQDAFVSRLKARDLTMITPADFIRNCTTAYKNAMPQVVENNNVQKFIIKGIRPRVNPVNLDGQPCKACRWAVVNPETKTKIKCSKYHLGSRDMLNHILIDHLQEKAQENGKLANRIAQFTCQWIGCKRNKEEREMSLLEFANHIRTHTSSLWTTPIVAPTEKSDSPTPAPYNHGSVPARESATPSASNTPKPPTPAQLPTSNASRKKNPSDSNNSDATKQKDWIIPRKTVKVVNVETAMTRDEQNPNAPLQTGGIPLSAVLVLRNIARNMRDNADVEGKEQSRKSLLFSGSLNDLFRIMAENRALAFHVSTLIHAITE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH54</accession>
    <name>A0ABR3YH54_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000305">
        <property type="protein sequence ID" value="KAL1887648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39476:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39476">
        <property type="entry name" value="NADH:UBIQUINONE OXIDOREDUCTASE 6.6KD SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="55" mass="6625" checksum="6456F8E2D4B4F38E" modified="2025-10-08" version="1">MQTKRYQYFRWTPRTARISFIYIFVVPSIVGMMAYKMDGLLDFRAKRKGDSLLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHP1</accession>
    <name>A0ABR3YHP1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">M-phase inducer phosphatase</fullName>
            <ecNumber evidence="6">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MIH1</name>
        <name evidence="9" type="ORF">Cpir12675_006460</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the MPI phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000304">
        <property type="protein sequence ID" value="KAL1887654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01530">
        <property type="entry name" value="Cdc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000751">
        <property type="entry name" value="MPI_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10828">
        <property type="entry name" value="M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10828:SF17">
        <property type="entry name" value="PROTEIN-TYROSINE-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00716">
        <property type="entry name" value="MPIPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 6" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="4 6" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="8">
        <location>
            <begin position="493"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="304"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="349"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1887654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="683" mass="74383" checksum="D061AB3E546EF297" modified="2025-10-08" version="1">MDASSPLAAFQQSPLLRNSQFPWAAQRDFRFPRFSAASSATMSLREQLQRASGSNGDFMSLKEVRGSSPAASLAADMSQNLGLDNGNSPRFPTPRRTLFASATSNARAANYITATQPSLLSSPHCLPNISNNTTSSPSLPTNTPCRTLALPAASLDAMMMASPSFDLEDDDDADISADIELDMDSEEDFDDEDSMMLDSPLQCMQRQPSYTGSIDVRQDCRSIPRRGSLSRAKGYSLHRDAQPFRFGALSSASSFTASNSSTSSLVSGEGGRLSRMSSYSSLAVDETSFDSSFNISDVEEGVPSFISGSSTRPQTSSSNASANAPVASMPTVPPMFRSRMSLQSLNGDMRSAARNSGSPISHIRRPSNPFSRSRKQFRRTLSMFGSADEVMRPRADPGPAIIPPSPATAMPTAATIVSTVTDLMPLPTVTPVSPVCGTALTAALESVMDAVDDASVPSEPLLPHFLLDDPTDSIPRITKETLMEVLDGKFSSNYDSKMVIDCRFEYEYEGGHIDGAVNYNNKELLTKQLFDTPIAGRSLLIFHCEYSAHRAPMMARHVRARDRDVNRENYPRLTYPEVYILEGGYSKFFENHPNRCYPQNYIEMLDKAHERTCERELDRLKTRKAPSFSRAKTFAYGASGSGVLGSRMSSAMCPVSPPPRSMAGASMCRSPVVFATPRRLASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIC2</accession>
    <name>A0ABR3YIC2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">GCR1-dependent translation factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">GDT1</name>
        <name evidence="9" type="ORF">Cpir12675_006381</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GDT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000290">
        <property type="protein sequence ID" value="KAL1887894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001727">
        <property type="entry name" value="GDT1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049555">
        <property type="entry name" value="GDT1-like_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 165"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN HTP-1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01169">
        <property type="entry name" value="GDT1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01214">
        <property type="entry name" value="UPF0016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046817465" evidence="8">
        <location>
            <begin position="22"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="261"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="323"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="405"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="446"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="479"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="29"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="47"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="147"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1887894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="502" mass="53433" checksum="771757581D74CD61" modified="2025-10-08" version="1">MRLPTREYSLLLLLLPSLAAGVALTDTKASNKELESSNELPAVGSLAETTSTGLTNSLATDSTKTDTSIDEKGPVDGKDGKPHNGPWVETTDSKKEKEAGAVKKPTTETPSNTVIDGKKIPESNDGVMDDKNREAPKTGTTGNDGGVSEKDKARKQEEGKTGEKAKGNPETPKEAPPLPHSEEEKILQDSGQAVEKTPTTKGGVINDNTGLEVPGDLPEKVHDKPNPVPESAHKDHLDISKSTLGGASDTSPASSGSFHSFVLSFTMIMFAEIGDKTFLVAALMAMKHDRVVVFSAAFSALLVMTLLSAVLGHTVPVILPKKLTAFLASMLFFVFGARLLREGMAMSQDEGVSEELHEVERELAEKEKGGSLAAMEMGLGNRKGRFNSSGNTSNRRRPKTVFTGLSNLMNLFLSPAWIQTFIMTFLGEWGDRSQIATVAMAAGPDYWYVTVGALAGHFLCTSIAVLGGRAIAGKVSMKVVTIGGAISFLLFGIVYLYEAMSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIQ5</accession>
    <name>A0ABR3YIQ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006436</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000300">
        <property type="protein sequence ID" value="KAL1887722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="310" mass="34200" checksum="363EEF16A94FF564" modified="2025-10-08" version="1">MLPEGIFEEIYNHLGLDRSLKPCQVFDLIGGTKTGGYGFEHFHLFTYMFRKTHSQNYSRIIAVMLGRLGMDLAHKSLVSESDNHPNPPASNISGPELEAAISAMIGKSRSDSQPKLQLKSGAPEPNKGTHKDILFKDKHCTKTAVLVMTKCNVETRPALLATYKMSRGFDQCTVLVVAKVLSTSDSLAGSIEIGRDDESFVDAKFGYNNPCEILISEAKKEFQGRDIIILSIGTDVNNVVPIDCSESVTDTTMKVVTSAKAADQRLQGDYRDTRAYHRFNVEDGLKNPEDKACGEVSKISALSRNYVNEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJG3</accession>
    <name>A0ABR3YJG3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CREG-like beta-barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006276</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000275">
        <property type="protein sequence ID" value="KAL1888170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055343">
        <property type="entry name" value="CREG_beta-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37273:SF1">
        <property type="entry name" value="ADL397C-AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37273">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13883">
        <property type="entry name" value="CREG_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045439129" description="CREG-like beta-barrel domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="CREG-like beta-barrel" evidence="2">
        <location>
            <begin position="42"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="295" mass="31898" checksum="C581879CD8A59EBE" modified="2025-10-08" version="1">MPTTMRPDISFLLVAAASVVSAAFVQDPIAPQIWPHRIPTAYESAVMGRRILGLVKLGDIATVFPTSSTPESAYGLSGSIAGATSAPPAVAGIPITMMDYLADCEDRGNPTLLAISIATTFRNAAQGSNVTLSLRWIPPYPPAKRMSLVESLISWLGFGEYKVDTKADSSSEDVSSATPDTVPYSAANLPRVSLIGYIEPITPEQVGPTKLAKCFVERHPDAKYWLPGNPIHRSSWARLVVTHVYWVGGFGDRAYIGWIPVEDWNKVSVAEWEAITLPGEKPGWSEWMVGADVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL48</accession>
    <name>A0ABR3YL48_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zinc finger double-stranded RNA binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_006052</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000246">
        <property type="protein sequence ID" value="KAL1888755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040050">
        <property type="entry name" value="ZNF830-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13278">
        <property type="entry name" value="ZINC FINGER PROTEIN 830"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13278:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN 830"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger double-stranded RNA binding" evidence="8">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="58"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="232"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="292"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="155"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="322"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1888755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="349" mass="37787" checksum="8EA4FD07B3B22638" modified="2025-10-08" version="1">MTDVRSLLRQQQAARRITHKLAIYTDSGKLACLLCDELVKTESLWDTHIRSKGHRLRVQTQTMEAERPESRGQKRSAPILTPTQNSPDAEMEEPASKKRNLSVPLDGDEGKDARVYASTSQINASKDPRLGSSVPRRLSGAPSAGMEIQIPSRPATPSRSTIQSATSGSSDMALPTPNADSVSVSAAEKRPTTTDAGAIDEDEWAAFEADIAATTTAYSADATISAPAMTAEEVATAAEQSAKEGHKEPTMKQIEEEKEDAKRLLESEFEEMEELEAKVRQLKEKREALRKQVGNTAARVQAGQVGPEKDISADANTNNPDGGDDDGSDDDESDSEDDWAGFRFKGTIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLE1</accession>
    <name>A0ABR3YLE1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA pseudouridine(55) synthase</fullName>
            <ecNumber evidence="3">5.4.99.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PUS4</name>
        <name evidence="8" type="ORF">Cpir12675_006089</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a uridine in mRNA = a pseudouridine in mRNA</text>
            <dbReference type="Rhea" id="RHEA:56644"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:14659"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pseudouridine synthase TruB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000251">
        <property type="protein sequence ID" value="KAL1888660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160148">
        <property type="term" value="F:tRNA pseudouridine(55) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01080">
        <property type="entry name" value="TruB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014780">
        <property type="entry name" value="tRNA_psdUridine_synth_TruB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767:SF2">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE TRUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767">
        <property type="entry name" value="TRNA-PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pseudouridine synthase II N-terminal" evidence="7">
        <location>
            <begin position="79"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="237"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="437"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="450"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="494" mass="55732" checksum="6D1F29873A958569" modified="2025-10-08" version="1">MRFKSPPIFNMTTQKVVEGVFGINKPLGMSSAQVIRDAQQQLNPSKMFAPWIKQEKEKRTVESHSQQKRRRHVKREIQVKMGHGGTLDPLATGVLILGVGSGTKCLQSFLKCTKTYETIVLFGASTDTYDRSGRVLMRRPYEHITKEAALKAIDEFRGTIKQVPPLYSALKMEGKPLYEYAREGKPIPREIPTREVEVKELELLEYYEPGTHKFRWPREQADAAETRLAQQVWKLEGEDIGSPAATQESEASSEEEIRESEALAAHEATKRRFEESVDELVRDCPSRKKRRLEKSSGRSQVPMMSGALNDHSETAEKASESKKDRKDRKNIPNNQNSDPSRGHNLVPEVDESLPPPWEGKGPAAARIRLTVTSGFYVRSFCHDLGIKLGSVALMSELCRSRQGDFKLNTPSVLEYSDLMKGEEVWAPKIEAMLRQWEEKHSPSPKMAPGKTEHVETDQKPEPAKVVAPTKPETATGASKRTLQEDEKSWNGIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLN9</accession>
    <name>A0ABR3YLN9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Molecular chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">JAC1</name>
        <name evidence="5" type="ORF">Cpir12675_005882</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HscB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000226">
        <property type="protein sequence ID" value="KAL1889216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.20">
        <property type="entry name" value="HscB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004640">
        <property type="entry name" value="HscB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036386">
        <property type="entry name" value="HscB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009073">
        <property type="entry name" value="HscB_oligo_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00714">
        <property type="entry name" value="hscB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14021">
        <property type="entry name" value="IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14021:SF15">
        <property type="entry name" value="IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07743">
        <property type="entry name" value="HSCB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47144">
        <property type="entry name" value="HSC20 (HSCB), C-terminal oligomerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Co-chaperone HscB C-terminal oligomerisation" evidence="4">
        <location>
            <begin position="180"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="56"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1889216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="263" mass="29241" checksum="B2C6C30ED44DCAB6" modified="2025-10-08" version="1">MNSFYSAGRLQAARACARSSRLPSPDIACPRAVQLPNMACRLLHHIPGYCRPADSNLKGPHSSSPPSPSTKTKAENTASPATGSAPRTHYDIFPETLRQGPPPHGHFPIDVRALRREFLRLQAQAHPDLHPAKDKVRAQSMSALINTAFKTLSNPLLRAQYLLGLQGINPGEDEQARVDDPALLMTVMEAHEQIQEAKMEADLMSLNEENEERIKVSEDILEKAFKEDAIQAAVEESVRLRYWVNIRDSIHNWEPGKPGTVQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP62</accession>
    <name>A0ABR3YP62_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mitochondrial ribosomal small subunit component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RSM19</name>
        <name evidence="5" type="ORF">Cpir12675_005660</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000205">
        <property type="protein sequence ID" value="KAL1889775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="entry name" value="30s Ribosomal Protein S19, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_uS19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_uS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020934">
        <property type="entry name" value="Ribosomal_uS19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_uS19_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="RIBOSOMAL PROTEIN S19P FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880:SF8">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US19M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="Ribosomal protein S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00323">
        <property type="entry name" value="RIBOSOMAL_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1889775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="90" mass="10149" checksum="067982E27F18F1FF" modified="2025-10-08" version="1">MQPSRVLLKRSVWKGPHIVPLPIVRPAPGQKAPPIKTQARSATILPNFVGLKFQVHNGKSYIDVLITEEMVGHKLGEFSPTRKPFIWDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPU3</accession>
    <name>A0ABR3YPU3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycoside hydrolase 2 (Mannanase, beta-galactosidase)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">BMS1</name>
        <name evidence="6" type="ORF">Cpir12675_005606</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000201">
        <property type="protein sequence ID" value="KAL1889918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01882">
        <property type="entry name" value="BMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012948">
        <property type="entry name" value="AARP2CN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039761">
        <property type="entry name" value="Bms1/Tsr1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037875">
        <property type="entry name" value="Bms1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007034">
        <property type="entry name" value="BMS1_TSR1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030387">
        <property type="entry name" value="G_Bms1/Tsr1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858:SF2">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BMS1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08142">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04950">
        <property type="entry name" value="RIBIOP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00785">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01362">
        <property type="entry name" value="DUF663"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51714">
        <property type="entry name" value="G_BMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Bms1-type G" evidence="5">
        <location>
            <begin position="64"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="314"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="396"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="559"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="627"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1101"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="426"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="470"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="481"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="565"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="644"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="690"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1101"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1153"/>
            <end position="1162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1889918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1162" mass="131067" checksum="F74EEEF9C1586D67" modified="2025-10-08" version="1">MDQLHKPHRKSKDRKKPAPSGERNPKAFTYANAGRLNRAAARSHDIKEKRLHVPLVDRIPDEPAPRLVAIVGPPGVGKTVLLKSLIRRYAKETISDPQGPITIVTSKKQRLTFVECPNELEAMVDIAKVADVVLLMIDGNYGFEMETMEFLNVLAATGMPGNVFGILSHLDLFRKPQALKDAKRRLKRRLWAELYQGAPLFFLSGVINGRYPDREIHNLSRFLSVMKNPRPLIWRNSHPYSVIDSFRDITHPTKIEADAKCDRSIVLSGYLRGTNFAASGQRIHIPGLGDFSIANIEVLPDPCRTPAMEKALEQATGKRGKRRLDEKDKKIHAPMSDRSGLKIEGDAIWITREKGFQFDREDEEGERGEGEELIIGLQGERKLIGKTDQGVQLFKDGEKVQQAEDDEPNDTGRKTLRRAQFAEGQGPEDFDEDFDGSDDKDGDDDQIPSDSDAEEQEFDDSRLGAMFHKNTNDKNTHDEALAFADSDSDLGSLSGSDAEPGSFSDEDFDEDEEVAALRWKDNIASHVASLSKRPAFRPVDLARMLYNDTMQPSVVLKRWAGQSDAENEESEEENIEDEEDGEEFFKKKQSAVDAQEEDRTIPKYNYEELAAKWGNSESIEALGQRFAAAASRGGHNSPGSGGSDNDEDPFAASDDEGDGAFEDLESGEKHGPDAGKTGAEAPESAEDIEAERQRNAERKEELKLRFEEEDREGFLNDKANARRENGATEQFGEDEWYDMQKSLLQKQLDINKDEFAQLDERQRVAVEGFRAGKYAKIVLDGVPAEFVEGFNANMPIIIGGLAPTEDRFGFVQVRIKRHRWHKKILKTNDPLIFSLGWRRFQTMPVYSISDSRTRNRMLKYTPEHMHCFGTFYGPLIAPNTGFVCFNSLGKKTTGFRVAASGTVLSVDESTEIVKKLKLTGVPFKIFKNTAFIKNMFQTSLEVAKFEGAAIKTVSGIRGQIKRALSKPEGHFRATFEDKVLVSDIVFLRAWYPIKPRRFYNPVTNLIGWQAMRLTGEIRRAENIATPLPKNSQYRKITRETRHFNGLRVPRALAASLPFKSQMVSTKKQKKDTYISKRAVVLGGEERKARALVHMLSTINKDKEAKRRAKKDENRAEFKKRMAGLEEKKAARERQEKKDFWQKEGKKRTMAEQSGGGGKRGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQK0</accession>
    <name>A0ABR3YQK0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">LSM complex subunit LSM3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 11" type="primary">LSM3</name>
        <name evidence="11" type="ORF">Cpir12675_005474</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Binds specifically to the 3'-terminal U-tract of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">LSm subunits form a heteromer with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000189">
        <property type="protein sequence ID" value="KAL1890255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01730">
        <property type="entry name" value="LSm3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034105">
        <property type="entry name" value="Lsm3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040002">
        <property type="entry name" value="Sm-like_LSM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13110">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="13"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1890255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="96" mass="10875" checksum="FE3452D198DC405B" modified="2025-10-08" version="1">MADDEATSSHVSEPLDLVRLLLDEVVFVKLRGDRELKGKLYGYDSHCNLVLGDVEETIYVLEDEEEDEELKTISRKAEMLFVRGDSVVLISPHTPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRM5</accession>
    <name>A0ABR3YRM5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VWA7 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005132</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000164">
        <property type="protein sequence ID" value="KAL1891006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056862">
        <property type="entry name" value="VWA7_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25107">
        <property type="entry name" value="VWA7_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047444018" description="VWA7 N-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="16"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="VWA7 N-terminal" evidence="2">
        <location>
            <begin position="56"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="143" mass="15310" checksum="24AD62CA943A2721" modified="2025-10-08" version="1">MKVLNLLHLAPLAGAFFPTKFRDGLEGRPGTSHEALTVESLSELASTWDIISSNATAADGTVYLPRSVVNAIRAVGRASAEVDVLETTDATWHFDGERIYEGQLLLTALRGAIVSSLQQGDGETARAFLGKALHGVQDFYAHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRS8</accession>
    <name>A0ABR3YRS8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA repair protein rad9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000175">
        <property type="protein sequence ID" value="KAL1890690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046938">
        <property type="entry name" value="DNA_clamp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007268">
        <property type="entry name" value="Rad9/Ddc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15237:SF0">
        <property type="entry name" value="CELL CYCLE CHECKPOINT CONTROL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15237">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04139">
        <property type="entry name" value="Rad9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55979">
        <property type="entry name" value="DNA clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="474"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="508"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="539" mass="58461" checksum="C7FF9BDC6ED9CA7A" modified="2025-10-08" version="1">MSVLSFTLSDDGVSSLRDALICLNKFHDEVSLEAQRDKFMLSALNPTKSAYASFSFNTSRFFSRYKFNSSSGSEKFYCRLYSRVLIALFRARGGGGGGGSGGDGSGKDGSGGDRGATIDHCTVSIEDGPSVKSRMVLRIAFRNGCVATHRLTFESAVVVHARFNAEEATHRWTIASRTLRQIMEHFGPGVELLDINSDEDHINFNCYMEKALNADEVLKKPLQTSIAVDLDEFEDIDVENGLHIIISVRDFRAVVQHAGILSADLQARYSIPERPIRFGYDGDAVSCEFLLMTVGERGSATTAAQRAKRKKAENATAAAPVLDAAVATSAAAVSVNSANTRSDKQRPPPVMVAVAGRRASLVHLSPNSGTRTTANRAAVLAMDNAQPAVPAVGIMPPPSRGGRAEKRSGQEHAQQKEQQQQQSADTSRTRMSFFDIRPQASQVAPPRASTVALEDGLFVGDDGWEPVRVGEDEDEYEAEDGFTGLGWDNSSRDDSTMPAQGDRALPNEQINEESLGSQDGLEPTQRLSDVQKHDLFYGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSS4</accession>
    <name>A0ABR3YSS4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein vip1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">vip1</name>
        <name evidence="4" type="ORF">Cpir12675_005156</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000165">
        <property type="protein sequence ID" value="KAL1890999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32343:SF10">
        <property type="entry name" value="RNA-BINDING REGION RNP-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32343">
        <property type="entry name" value="SERINE/ARGININE-RICH SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="3"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="264"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="289" mass="30847" checksum="F667E4DD73DAC188" modified="2025-10-08" version="1">MTNVVYVTDISASTDDKEIKEFFSFCGKVTAISIEADGADKKKATVTFEKDTAMKTALLLHHTQLGSSKITVTGSANLDEHNDPTPAQRDGDEITQEEKPRSRILAEYLAHGYVVGDAALEQAVVLDKKHNVSQRFLTTLQGLDSKYKATDRARATDESYGISTRGKGLLFGLNSYFEKAVGTPAGKKIAKFYEEGSKQAQDIHTEARRLADLKKDQAGGSAYRASGLEKVFGKAKCSATTDSAGVPNANVPLSPQSAASPAAALDIKVGYPSDTKTAPGPDSKPPPSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSY8</accession>
    <name>A0ABR3YSY8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">U3 small nucleolar ribonucleoprotein protein IMP4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">IMP4</name>
        <name evidence="4" type="ORF">Cpir12675_004971</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000154">
        <property type="protein sequence ID" value="KAL1891459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10480">
        <property type="entry name" value="Probable brix-domain ribosomal biogenesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044281">
        <property type="entry name" value="IMP4/RPF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22734">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22734:SF2">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Brix" evidence="3">
        <location>
            <begin position="86"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="36"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00040513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="298" mass="33773" checksum="FA4BA0B673D0A6D9" modified="2025-10-08" version="1">MIRKQARQRRDYLHRRAITLRDAEISEKRAKLRASLASGKPLDPSISKDTGLRKDLPYDESQPDLTTHERLGMDDEYAELSGIVEPRIMVTTSRDPSTRLAAFSKEIRLLFPTAIRLNRGNLILPELVHSCKSNGLSDVVLLHEHRGTPTAMSVSHLPHGPTISFSLHNVVLRHDIPGSVRGTVSEAYPHLVFDGFTTPLGKRVVKILKHLFPPREPLTSKSQLGSRVVTFKNMDDSIEVRHHVFVRTGHDSVELAEVGPRMTMRAFEIRNSTLENKDGDVEWHLSQYTRTGRKKNYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTG1</accession>
    <name>A0ABR3YTG1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GTP-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GTR2</name>
        <name evidence="10" type="ORF">Cpir12675_005104</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the GSE complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the GTR/RAG GTP-binding protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000162">
        <property type="protein sequence ID" value="KAL1891135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11385">
        <property type="entry name" value="RagC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006762">
        <property type="entry name" value="Gtr1_RagA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039400">
        <property type="entry name" value="RagC/D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11259:SF2">
        <property type="entry name" value="GH16429P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11259">
        <property type="entry name" value="RAS-RELATED GTP BINDING RAG/GTR YEAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04670">
        <property type="entry name" value="Gtr1_RagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="25"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="399" mass="44999" checksum="C2E80A22E44C442A" modified="2025-10-08" version="1">MASPIPSSAFIKAVRDKILSRQRMANQLTSRSSRGQNQNRSGMMRGDSNRQLPSEPLMQTPATVKGRPRLLLMGQRRSGKSSISSVVFHKLAPQETLFLESTARIQNDQMTSFMDIQVWDFPGQIDIIDNPSFDMEAIFGELGALIWVIDAQDDYLEAVERLNATILALQDSYPHINIEVFIHKVDGLSDDYRLDIQRDITIRVQDELSDQGVENAPVNFHMTSIYNHSIFEAFSKVIQKLIPRLGTLETMLTDLCRTCHFEKAYLFDVVSKIYIATDNSPADMPSYEICSDYIDVILDISEVFGSWTRPAENATRLEGNAWAEGAPPKIADQVAYSGAESCLVLHDTSRPIMLREVDKHLALVAIMKEESYAKMPLVTMNVEIVAKGLQQFFEITKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTV9</accession>
    <name>A0ABR3YTV9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_005010</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000157">
        <property type="protein sequence ID" value="KAL1891326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039970">
        <property type="entry name" value="TF_Grauzone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23225:SF2">
        <property type="entry name" value="AT09679P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23225">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="252"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="4">
        <location>
            <begin position="327"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="138"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="318"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="157"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1891326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="451" mass="49748" checksum="1997189D2D9F7CA2" modified="2025-10-08" version="1">MDSQVLRTYAAQPTFIGGAIDPFTTGLSIGLNACYFEAPTTRTRQVDWASVDAGAFPAELLAGSPDITTAIPQPVAVILNPSLYDPNFCSFEPDISIIDHSGYETSPSTNSFAASETTEGMARNFSCHSLDSVLGPVGFSHSPSRDSTPGLLPCPRSGTSSTQMSPNLVPALGPASKITPNGSSELPSIGPCLFPFKGSSQPPRSQTQQSQPSTYQPQASRNTIQLHGRPSQRGNSTVARGAKAKSKLSEIYPCQFAFAGCRSTFPSRNEWKRHMATFHIMERYYKCTEEHRPGRGPCNEVFNRPDLLMQHVRRILKEDDGDEQSVPRAEVERRRDQSLVTRLQGPPPPLRCPSPQCNTIFPETKNSWDARAEHISKHHERKDTSIVDFIGHMAHDYDFVVWALSIGAVQITEYGEYTCEAPVETTHQIARKFKKTPKKAPKSKKQVLRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTY8</accession>
    <name>A0ABR3YTY8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005002</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000156">
        <property type="protein sequence ID" value="KAL1891352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39605">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39605:SF1">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="142" mass="15364" checksum="0CFF72D9CA72FA69" modified="2025-10-08" version="1">MLREEYQADTALEVYFARSLGLALIALALFHIVLSGAIPLTSSLSEVAVSPFASAIMLISALHHAGVASYCYGMYTWAGQSAFAFGLLASAFLSIVGLGCFMFAGDTSTVSKNLHLDKATSSFPFKNAEAYHEKKRRIRKDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU75</accession>
    <name>A0ABR3YU75_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcription regulator Rua1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004956</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000154">
        <property type="protein sequence ID" value="KAL1891446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028012">
        <property type="entry name" value="Rua1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28125">
        <property type="entry name" value="MEIOTIC EXPRESSION UP-REGULATED PROTEIN 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28125:SF3">
        <property type="entry name" value="TRANSCRIPTION REGULATOR RUA1 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14616">
        <property type="entry name" value="Rua1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription regulator Rua1 C-terminal" evidence="2">
        <location>
            <begin position="441"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="546"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="667" mass="73051" checksum="BB4526C15E43C90C" modified="2025-10-08" version="1">MDTSESQIQQQSQSHLDACSFAFSTPAPVKYRHDDPPRSTPMVTMTPGDMTIKAEATVSPGMWQTPVSAIRPRPATIHEGFSSCCTGDDHRSLPAWDSSTMSLQQTPSDTLYSSRPVSMHQDFLNPMNSDYSSWASRKCDEGLEFPDMQIGQAYTADEAIPILDLRFQNPQTEGMDGTIAPRRMSGSSFTMSTNGTLSDMPSYEDFSSALSEAPSLSSDYPPPSNRTSLLSSCTQLSPVASPRMSSQGGRTELVRTQSRGHASPSPRPNVRSTPYNIDVGRANNKRWSTGSYGTQQNRNTGPYSMYHAMPTTQDSSTVGGGMPLDYSAMSAAQQNPYMITGTPYRNSMLLPTQLPSQVPPHTYSTDMNALHVPPPLMSHGLFRMLQSNGDQYAMPGHYSDLSDPPDLYSALNEQQIPPPPEDMNPSDPDLVPHEQELRFEGDLYTPRWVRGHGNKREGWCGICKPGRWLVLKNSAYWYDKSFTHGISATTGSPFQEPLETRRMDGNPDVWEGLCGSCNDWIALVSSKKKGTTWFRHAYKCHTHPKIKDAPKRRRESNQNRSLAASTMAKPKVEPHMPHTPPGQHMDPNPAMAMGGTGTSGGDTRAAALSMPPATMSMIPTHMMSTGSTPAHLSQPTPHVSAPPMRPVGQFSRGLPPPISEGTPPGMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUW2</accession>
    <name>A0ABR3YUW2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ADP-ribosylation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ARF1</name>
        <name evidence="13" type="ORF">Cpir12675_004704</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000139">
        <property type="protein sequence ID" value="KAL1892053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04150">
        <property type="entry name" value="Arf1_5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045872">
        <property type="entry name" value="Arf1-5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10 12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4 12" id="KW-0519">Myristate</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU369003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1892053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="183" mass="20981" checksum="32DCB7820155ACE4" modified="2025-10-08" version="1">MGMAFSKVFDRLWGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNIQFTVWDVGGQDKIRPLWRHYFQNTQGIIFVVDSNDRDRITEAREELQRMLNEDELRDAILLVFANKQDLPNAMNAAEITDKLGLHSLRQRAWYIQSTCATSGDGLYEGLEWLANTLRKAGHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVM0</accession>
    <name>A0ABR3YVM0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12">Protein transport protein BOS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">BOS1</name>
        <name evidence="14" type="ORF">Cpir12675_004572</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">SNARE required for protein transport between the ER and the Golgi complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10 12">Belongs to the BOS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000132">
        <property type="protein sequence ID" value="KAL1892419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15863">
        <property type="entry name" value="SNARE_GS27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027027">
        <property type="entry name" value="GOSR2/Membrin/Bos1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230:SF1">
        <property type="entry name" value="GOLGI SNAP RECEPTOR COMPLEX MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230">
        <property type="entry name" value="VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12352">
        <property type="entry name" value="V-SNARE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028865">
        <property type="entry name" value="Membrin-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00040957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR028865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1892419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="268" mass="29213" checksum="5A34445DC93C9BE5" modified="2025-10-08" version="1">MNVLYNTALRQSRAIRADLDRINEALGSGAVVTSGDVGNVSASLATFTKAIEDYQALARQELVPKKKDEASERVKRFRDELTDFRVRVDVVKKHREEAAHQANRADLLGRRPYATSTTPENPYAGIGASSSTGGFGIGPAGSGGVHARNSSIGGTGAGAAPPLGGYSFGSGDVARENHALREQGFFQNTNSALDDYIARGQAVLSDLNSQREMMKNTQKKLYSVANTLGISGDTIRMVERRAREDKWIFWAGVIVFFLFCWLVLHFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVP8</accession>
    <name>A0ABR3YVP8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Malate dehydrogenase</fullName>
            <ecNumber evidence="3 9">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">MDH1</name>
        <name evidence="12" type="ORF">Cpir12675_004564</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 9">
            <text>(S)-malate + NAD(+) = oxaloacetate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LDH/MDH superfamily. MDH type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="3 9"/>
    <dbReference type="EMBL" id="JAWDJO010000132">
        <property type="protein sequence ID" value="KAL1892411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01337">
        <property type="entry name" value="MDH_glyoxysomal_mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="entry name" value="Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001252">
        <property type="entry name" value="Malate_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010097">
        <property type="entry name" value="Malate_DH_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01772">
        <property type="entry name" value="MDH_euk_gproteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540">
        <property type="entry name" value="MALATE AND LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540:SF73">
        <property type="entry name" value="MALATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="LDH C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00068">
        <property type="entry name" value="MDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0520">NAD</keyword>
    <keyword evidence="5 8 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lactate/malate dehydrogenase N-terminal" evidence="10">
        <location>
            <begin position="23"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="Lactate/malate dehydrogenase C-terminal" evidence="11">
        <location>
            <begin position="168"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1892411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="340" mass="35725" checksum="FAC9D2289EAAD428" modified="2025-10-08" version="1">MFAPLRSTLQRRAFSASARDMSKVVVLGAAGGIGQPLSLLLKMNPKVTELALYDIRGGPGVAADVSHVNTKSTVKGYQPTPEGLAQALKGSDVVLIPAGVPRKPGMTRDDLFNTNASIVRDLASACADHAPDAKILVIANPVNSTVPICKEVFKLKGVYNPKKLFGVTTLDVVRASRFVSEIKDTNPDQENITVVGGHSGVTIVPLFSQSSHPELSSNADLVKRVQFGGDEVVKAKDGAGSATLSMAMAGARMADSILRASQGETGVVEPTFVESPLYKDQGIDFFSSKVELGPEGVKNILPVGNVDAAEKALLDACFVDLKNNIAKGVSFVQSNPPKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVY4</accession>
    <name>A0ABR3YVY4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_004698</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000139">
        <property type="protein sequence ID" value="KAL1892047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1892047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="146" mass="16575" checksum="1AB3DA3E2995EEE5" modified="2025-10-08" version="1">MDVKDYSINEATRFHRRHNRLTNKAQIRVTPQDKGWSTFSKMHYYETAAKMIPDKEIDRIIVEQREKETYGTDFQAVTIETLRFSFRSPSQDGDTNVDPVGARAAKLIAEDDLEAVAEIVENAAVAHEKAILEGETEGFPDTSLDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVY5</accession>
    <name>A0ABR3YVY5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_004662</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000137">
        <property type="protein sequence ID" value="KAL1892154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01466">
        <property type="entry name" value="vWA_C3HC4_type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051266">
        <property type="entry name" value="CLCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10579">
        <property type="entry name" value="CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10579:SF43">
        <property type="entry name" value="ZINC FINGER (C3HC4-TYPE RING FINGER) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15411">
        <property type="entry name" value="PH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="156"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="4">
        <location>
            <begin position="710"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="225"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="636"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1082"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="86"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="235"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="262"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="298"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="327"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="354"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="659"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1090"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1107"/>
            <end position="1120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1892154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1247" mass="136904" checksum="F59B2BD8BFA74B55" modified="2025-10-08" version="1">MFSRSKRGFGNGPFSASTTSFHSSSSHPERPSREREHHFSDLHDRLRKKKRDRDEPPVPALNPILYEPGPSYPVKGTSISANTYNQQQQQQQQQQQQQQQQQQQQHQQLQLQPQPQYHTPQERNPSIASGGTGQQAMSSSDRSRGRRERTFVGSECAVCEEPLEHTLRGERILQFSCTHVAHEACFYALIKEFESQYCPTCDAPLHLDTSRGGNVIDIEKISNMVRSPSAHDSRSQATTTPTPGSGRNSAANSAWDAPPPSSSQEPLPVTSPTTARFSGTESNPRNTAMSMPGSLNGRDTRDRDGRDTRDSSTARVRDPSTTRARDSSQSGGERYTLRSTTHTHQRSDSEVTGAASTTSFSNGYPETTQSGPSRRHDYDVQAMETTISSPRPIARNPIPHPTVIVRSEFPTINRSRQQQSITCLITIEVPDNKWQADPEDLGVPIIPLPQPVPVSTARSEDGYARPPSPVRTAPRFYPYESREVLDEITENLRNRVDNWHGLDFGRFGRLRLYGTLRVGKDRVSWQELECYLFAEMLICVKEKKINQQMAFNPDDAASGLPKKTTRCTLKGSILIKKHLNEVLEIASPDEISHILTLSLSVAELPQFHLKFENRNQLKLWQQALLDLNAVEASPVRSPEYDRRGAGDYSEVEDDDWGNSTTSSSTRQRVSSVASWGVPKSSTPGPVDYANSIAARTPPLSMQASVHVPIDVVVVVPISSSMQGVKINLVRDALRFMVSTLGERDRMGLVTFGSGGGGVPIVGMTTKAWHGWSNVLGSIKPVGQKSHRADVVEGANVAMDLLMQRKYNNPIATIMLISDASTSDADSVDFVVSRAEAAKITIHSFGLGMTHKPDTMIELSTRTKASYTYVKDWMMLRECLAGCLGSMQSLSHQNVKLKLKLPEGSPAKFHKISGALQITKRAAGRDAEASLGDLRFGDRRDVLVQLVIMPDNATQEALPQDTWDTLVSGLEALGGNMDSDEQRTMSVEEVPLIQADLTWGDILRDGTLTHMPRPSLLAITMLPVSNNKKSWAMVPPIPPHPGIVQRRMELLTSDMLTRALTLVSRGQHDRAHTLLNETRTILKGLGKGGLPPVPPPNRSTPPIPVPSQPSVSNSSPTSLTPPRKRTPSPPTPTSSSTANGGYGNTLAYSRSSDGLGLNVGIDPVTVAALDAELEASLEWINHPAVFGRDSRKAVLQAIGVISSQRAFTFRSSIEALWAGRVSGVKKLTGRSREWRDEGGGEGGIMEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVY6</accession>
    <name>A0ABR3YVY6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cochaperone protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SGT1</name>
        <name evidence="5" type="ORF">Cpir12675_004482</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SGT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000128">
        <property type="protein sequence ID" value="KAL1892554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06466">
        <property type="entry name" value="p23_CS_SGT1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007699">
        <property type="entry name" value="SGS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044563">
        <property type="entry name" value="Sgt1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45862">
        <property type="entry name" value="PROTEIN SGT1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05002">
        <property type="entry name" value="SGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51048">
        <property type="entry name" value="SGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="4">
        <location>
            <begin position="222"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="SGS" evidence="3">
        <location>
            <begin position="361"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="177"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="343"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="203"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="343"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1892554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="446" mass="47593" checksum="3C0EA378FE9BEDCB" modified="2025-10-08" version="1">MSANTLATLGAQALEKRDWSTAISKYTAAISQTTSPLWLINRSKAFVGNQDYASALADSEAAFHAAVSRSNRKFMAEAQYRRAVALLRLGRYADADCAALWSLQLYGPGPASTPDDETTQVDSQGNYTARKELAAENIKTAMSGLDKKAAMEVSEVRNRMVAIQAFRQQCLGALERLPENDPRRKPTVSKVPAKNGAADTKKTPVTAAAPEAAKKGANQTAAKDLRTDFYQSTSQVTLSVFVKGVDKAQFAAQFIPDDDPTTSSAVLLNGLPVDGQDGATIKIVLGGPIIIAESSARVSPVKIELSLKKATVVKWNKGLTGAPESVTATESLATSTVATSEAASTSASALAGSTADETRPSYPTSSKKGPVNWDKLTQEEDDDDGKDVNHFFKKLYAGSSDDQRRAMMKSFLESNGTALSTDWSDVKGRTVETKAPDGVDVKPWKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW22</accession>
    <name>A0ABR3YW22_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_004724</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000140">
        <property type="protein sequence ID" value="KAL1892035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF30">
        <property type="entry name" value="MID2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="301"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="348"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1892035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="360" mass="37392" checksum="29D1911C52B4D117" modified="2025-10-08" version="1">MSNSTASTTSNNPYQDLGLSCPIGGSFYICSGEPTEFIGCCTSDPCLPAQRGVCPTSNLRNSSFNADAYHDIPPQKCSSENGEWYTCTGTVPPFIGCCGVNPCQRGSCPVSNVIPAELSIDPSDREVFLEAMSSATSASGTTDSAVTSTASASSDSGGSSSGIGTGAIVGIVVGAIAVTGMIIGFFIWKLKRRRSQGLNPETSTSAAYPSPATNVSPGQNIVYPSSMTPPANMPPDYQMPMMYTGGNSPSIMGNYNHPQYTDAHGLPMPIPHDTYAAPQGIYSQNTGKYGHQSVSTLATDLSNGQRNSEISQVSGQQSPGFVSNMAPVSELDGAAATPVLQEMPEATGTPTETKNTQSQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWZ5</accession>
    <name>A0ABR3YWZ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000131">
        <property type="protein sequence ID" value="KAL1892437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07187">
        <property type="entry name" value="YvcK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10680">
        <property type="entry name" value="CofD-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002882">
        <property type="entry name" value="CofD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038136">
        <property type="entry name" value="CofD-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31240">
        <property type="entry name" value="MATERNAL EFFECT EMBRYO ARREST 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31240:SF0">
        <property type="entry name" value="MATERNAL EFFECT EMBRYO ARREST 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01933">
        <property type="entry name" value="CofD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142338">
        <property type="entry name" value="CofD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="521"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="543" mass="58044" checksum="B226F3A2C0837CF7" modified="2025-10-08" version="1">MHDASIVAPTGDNSTQLRFADFDDSTHTLAPDSLPGSLSSGRAAVADSLADSHKTAPSLSQQQLNLPPTGIVIFSGGSAANTLVDVFEDVRQANKAALTYVLPISDNGGSSSEIIRVFGGPGIGDVRSRLVRLIPDNGNAENSALKALFNHRLVSDSVAAGHEWDKFLDGSHPAWLGISTPKLQLIRSIVNSFNFEAIKRTRPSSRFDFGSASLGNIFLTGARLFTGSFEAAIYLLSSICSVPASVDVVPALNTNFAHHIAAGLADGSVIVGQNNISHPGEPTAITLTCQAGDDEDPLMPRNVMTPVQEETAAHEEEAEAEDANLPGSLPALRKAAIAFSKEHEEDLPARIQRLWYINPYGQEIRISANPRVLDALAGCGTVIFSIGSLFTSIIPSLVLKGVGHALSRSDIRNKVLILNATVDREVGPSSNPYTAVDFVRTVAEACGQSMRPGLEVGDDLYSQFVTHLIYLDCPSSPKVDRQQLACMGIETIRLYGRQSKTERTLRYDSNGLAQALKAIVGTTESGHDRRRRNTMGGSTGRHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX01</accession>
    <name>A0ABR3YX01_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004546</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000131">
        <property type="protein sequence ID" value="KAL1892432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="266" mass="28469" checksum="2302C8CA1092B89D" modified="2025-10-08" version="1">MRSPVAIPRDSKPVLANIQRKDKAMHATGRPKSSTLQTPPESPYTLIDGHMDASMPSLNIAPDKTSPCFISSSTSSSCRDSYTRTKAGTGAAATPSFSQGAKPSLKPDPDNVIMNWDAIAVIKTNGTSRSNARGTNANNDNRDTSSNKDSTGSSDTVDLSSNKDSTGSSDTVDPTSCAALAKALEQIQAKHAKDYAMMEEFLMQTQRNVREEAAAAKRSMRTYGVSLFGVVFTGDIQAENDAIIFSVLALLWFLALVPLLKELLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX81</accession>
    <name>A0ABR3YX81_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Mitochondrial chaperone BCS1-B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Cpir12675_004488</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family. BCS1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000128">
        <property type="protein sequence ID" value="KAL1892559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057495">
        <property type="entry name" value="AAA_lid_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014851">
        <property type="entry name" value="BCS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050747">
        <property type="entry name" value="Mitochondrial_chaperone_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23070">
        <property type="entry name" value="BCS1 AAA-TYPE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25426">
        <property type="entry name" value="AAA_lid_BCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08740">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01024">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="BCS1 N-terminal" evidence="14">
        <location>
            <begin position="57"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="321"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="581"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="767"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="965"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="581"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="591"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="604"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="614"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="646"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="665"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="682"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="722"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="789"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="820"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="844"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="965"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="992"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1005"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1024"/>
            <end position="1039"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1892559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1039" mass="115703" checksum="A111B04AED1EB4FE" modified="2025-10-08" version="1">MTSSATGAVAATSLLTGSPLQSLFEAYTPGFSSLHSFFLKWLHIDITKLAMAVTICAMLSGAISNFGDMATRFYWWIARFLTASISITAKDRLNREVINWLSAHVLRPKKTGDIFSTLSCSEARTMIACSSETFTQNDAFIHSRCMEIDDSAVSDTSSASSLDRPAGRDNQRAPVHYLPTFGISWFRFEGKLFLVRRVNSGDSRSQKLPFVHESYSSEYQEAATGAEPLVIMCLGRSIDPIKRFLNACQEFTAKQAEKYVTVRTVRGRWRNDEWDVTILRPRRSLDSVYISKKVKESLIQDITTYLLPSTRNYYLSHGIPYRRGYLFHGPPGTGKTSLSFALAAYFNIPLHVINLQMIQGDSDLEVLFVALPPRCIVLLEDIDCICMKRRQKFATHDPDDGVSSSSESEDEQNQRSYFNLSLSGLLNVLDGVISQEGRIVVMTSNMPEKLDEALVRPGRIDRKVHLGLLSHECASEMFFRMYTDLLPTQAHVEEEDHFFRSDSTSRSYSSLTASKPQEHWSHRTLNELASDFAQAIPEEKLSPALVQGFLLDYKGSPFEAVREVRPWVDAEMKRLQIAEDLKQRSQEKKQNKMKYRRQSRKLNVMQQDLNLKQSMKDTLSRMEEMSRSEEKELRKKEAIARGEHVSSSSSSSTSDSSFDSDPSPKKHRKHKKKGDGKKKNKRNTDVKEGKNEDSDCSTKGSSSAPKDLMSPITPASTSEPDISMKVERQDQKSNLNVPLEDRQALVSPETVEDVEAVPEKLISVTDKTIAEEQKPTDYNIASARPENAAQATPQPEIQSTDLLEQEPVEQGAKPSQEARVLADNERRNDQINDDVERPQSTQQVKERLQKIDEEPENVREQRGGLQEAESFFPSAPATPASAPPSSVPSSILEVEDNAGGTPPLPSPVSQTRPHTPPRLLGKLPLLRRHASVGGSSADSTKSPRRLSANFGDVVGSVMDFRSLSSSRRNSNASMAAVAVTPSDPGASRNDMALAPTSSAEAASSPHERVQPHLHNESRIAASGAEEKVKDEKPREFVGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXE2</accession>
    <name>A0ABR3YXE2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mediator of RNA polymerase II transcription subunit 9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Mediator complex subunit 9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MED9</name>
        <name evidence="12" type="ORF">Cpir12675_004332</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 9">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Mediator complex subunit 9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000120">
        <property type="protein sequence ID" value="KAL1892923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037212">
        <property type="entry name" value="Med7/Med21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011425">
        <property type="entry name" value="Med9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07544">
        <property type="entry name" value="Med9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140718">
        <property type="entry name" value="Mediator hinge subcomplex-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0010">Activator</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="45"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="97"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1892923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="144" mass="16039" checksum="02F67F184E11197E" modified="2025-10-08" version="1">MTSRPGQPQQQLQQHPMALPETLSPDFLDTVSDLAVTLERLQSILNPHADPSLPNNPPGQDSVDPDAPKPILAKDLPTVTDPLKHKLKKARTQVVLLPDMNRTIEDQQEEIADLEKRIRKQQQILEKFKAGGADIVSESQQQDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXI4</accession>
    <name>A0ABR3YXI4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Serine/threonine-protein kinase iks1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">IKS1</name>
        <name evidence="9" type="ORF">Cpir12675_004285</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000117">
        <property type="protein sequence ID" value="KAL1893094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14014">
        <property type="entry name" value="STKc_PknB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF138">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE IKS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="697"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="729"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="794"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="175"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="84"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="126"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="545"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="545"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="583"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="836" mass="91462" checksum="FF0FD72087DE140F" modified="2025-10-08" version="1">MFVIDQPTRRHRNAIVVRDPTSQQLDIRLLTECPTCHRSLQPSVPPSDQNGFEGGQAGGRHESYVNPEYFRMLRAGAYSHRIANSGARPESEIRPGQGGAGSPPLTTSRSPLRRYVQPILPGSVSAPSNVFVENPEGEESPSLSQQSSPRPGQRQQPSSGIKKEAFSPHYFHTFFVEEKVLGKGGKGVVLLVRHQIDGCTLGHFACKRVPVGNDHAWLEKVLVEVELLAKLSHPNLVSYRHVWLEDVQLSMFGPSVACAFILQQYCNGGDLLNYVAGSAPAAITKEDLKAQLRRRRSRSQRDAPSIPRRQLPLEEIYSLFKDVTSGLVYLHANSYIHRDLKPSNCLLHHDDNSTVATTCLISDFGEVQVENAARKSTGSTGTISYCAPEVLRKDAAGRYGNFTTKSDIFSLGMILYFMCFGRLPYRNSNATDEEQEDIDLLREEILCWEGFHEERRERPDLPPKLYQLIKTLLAVDPTNRPSAAEVLAAIRNESPFESGMRGTGGVAPLGIRRVQLVDTPSPSATPTPGMLHTQYKTDTYSLLNPATDGRSTPQNNITLPATGPNPFASGSHRLSRSPARASGLDHGEIENPRLRSQTAAISHDQGQELTHHRRSVREIPINRQHADSENVSEAISASTALQCSPIHHSLLASDSSTAPHTNSLPLLMAPPTTMSASVRPAFAVLHTLRLAILVIDYYIDSLSAPLLLTLRWFLFLAKAASVVQPCAPYIPSISAALPLIGLAGLDLLLPLPSDLASNSLGAGLSSSPPARLGRHRTGRRIATVQGESENEAPLFTWTFSGAVVLGVVHMLVLWWTTRVGTLCVLSSAAKFDRDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY34</accession>
    <name>A0ABR3YY34_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_004360</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000121">
        <property type="protein sequence ID" value="KAL1892826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="OHCU_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036778">
        <property type="entry name" value="OHCU_decarboxylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37987">
        <property type="entry name" value="CHROMOSOME 9, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37987:SF1">
        <property type="entry name" value="OXO-4-HYDROXY-4-CARBOXY-5-UREIDOIMIDAZOLINE DECARBOXYLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09349">
        <property type="entry name" value="OHCU_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158694">
        <property type="entry name" value="UraD-Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase" evidence="3">
        <location>
            <begin position="13"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="167" mass="18431" checksum="D693409107462DE0" modified="2025-10-08" version="1">MDYRLPEPTTIASLSQAEQIAILDALFEPSPTIHVLMQPVLTSQTFESYTALIDACFAAIHRLASDATPENKATLHRILGSHPRLGAPKVDSKQSASEQAKLHSGSEETKQRLAALNSEYEARFPGLRYVVFVNGRGRPEIMEDMKARIARGDIELEEQEAIKVSGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY87</accession>
    <name>A0ABR3YY87_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004399</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000122">
        <property type="protein sequence ID" value="KAL1892815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="421" mass="47256" checksum="3A6E6E02379E7CD4" modified="2025-10-08" version="1">MFTAQPLTVVSPKPEPESLTSVSSQARYKDDSRDYNIASSHSPPPLNIGSHQATSAISGHGIPAPKTPDFYQNHPPPRHQKQEQHNTEAIYTSNHGYSNPETQGVPEATRALDVPSSHPQEESQSQSQSHTQSQSQFYATTGQAYGPPPPNPPYGGGPLPPANPYGAPYYPSAAWVPYPGPPAMSLQPQPQPSLKRTGNLFVDDLFDIAELRRNGRESLKEYMTLVTEASKVDAYRYDGALMQRMVDNRAQAISVLAALRQHLTEVTRSSEKCRFRSWVTGLVAWVPRISCLVLSLFLQVALTTPSGSIIPVIKSMFRRLAKNYPRLEAANDTEYAFKRSRTLTDYLKSSVFVKKRLASVSMFLFAVLYVFQNEILLRVSRTMYKRVRKLYDKVIRGQHMITEEDLTVMDGWRWRVIAWAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYJ5</accession>
    <name>A0ABR3YYJ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dienelactone hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000110">
        <property type="protein sequence ID" value="KAL1893431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47668:SF1">
        <property type="entry name" value="DIENELACTONE HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47668">
        <property type="entry name" value="DIENELACTONE HYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G01940)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="38"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="250" mass="27269" checksum="F9710E2D692C990D" modified="2025-10-08" version="1">MSAMPATHGHSAACCNIPPVVETGYKENGSYEQLGGFNTYTTGSSDATKGLLFIFDIFGFYPQTLQGADILGQKYRVLMPDWFEGKPADISVFPPDTPEKKEILTAFLSKNNPAIVGPKVKAYVAAASAKYPAVTSWAIVGFCWGGKVVSNVTSTDDTPFKVGAEVHPAMVDAEDAKGIKVPLILLASKDEDAEEVKKFEANLKGPKYVETYGDQIHGWMAARSNLSDPRNKEEYARGYKKLLEFFGEHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ50</accession>
    <name>A0ABR3YZ50_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_004011</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000105">
        <property type="protein sequence ID" value="KAL1893664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF199">
        <property type="entry name" value="MFS EFFLUX TRANSPORTER INPD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="274"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="427"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="453"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="477"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="511"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="124"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="617" mass="66056" checksum="A246D96C4507328F" modified="2025-10-08" version="1">MIHKPRPFAPRGSPEMSRASQNAPSTLPGSQFYPHTPAAKSAHSTIYINRTSTQTRPSPIYAPRTRRGPGLRYDYSEKSLSFDLSQSSISLAMGSDNDSDGDLDKDEDVQRLVEEDESNMKYPSSAGRLVILLSLCLNNSIIATAIPKITDEFASLNDVGWYGTSYLLATASLQLLFGKFYTFFCIKTVYISAIVVFEIGSLICAAAPTSLVLIIGRTIAGAGGAGIFSGALVILAYTVPIQKRPMYAGYVGSVWGISSLAGPLLGGLFADTLTWRWCFWINIPIGALSLTLLTLCLKIPKRAANRPSLMSIISQLDLPGNALFIPSVVCLLLALEQAGTKLPWNSPRIIGLLATSGTLFILFIILQFYLKDKATIPFRVMKKRTVWSAAIFTFHLGAAYVVSVYYLPIWFQAVKGASALQSGLMNLPLLLIVVVFSVIIGMAVTATGMFAPFMILSSVFMAAGYSLFEVLDVNSSPALWVGVQLIAGTGVGCGLQLPVMAAQSVLDMADVATGTAIMVFLQTLGGSVFVAVAQSVFAQALTKKLEEAVPGVDAEMILKVGATAVKNLGTESDVRLITVAYSEALREVFLVCAVTAGVSTIGSLAAEWRSIKNSNQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZP2</accession>
    <name>A0ABR3YZP2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000102">
        <property type="protein sequence ID" value="KAL1893821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="166"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="410" mass="45451" checksum="2FB5B75E7F2ED6D5" modified="2025-10-08" version="1">MFAQSQPPDRGQPPVRNPFLPFGLPNHTFVGIVSSVLSEIQPVSASWPEQDCLFADVGEYLVKCAEVLAEMADKLSNNQHIIYQMHQAQQQQQWNRDCFNYHFYLTQKHESIKTMASSLRNTAEALRLEWSKSDHPPHPHHNHAAPRGAVGIPQGYGQDHTHQHPAHQQHPQQQQHRHPAMAPSATPVSSVVPGPSTPQQQQHQQQQQHQQQQPTVSSGIGPTTSAAPGPIAGMARRDPPATRTAFPSAAYAPQNGGTPVAYPQESMYPLGSSATSGSMEPMEDELSAMDEERVRQLLNQPQHRGVGQHYCPLGERCDKGGVSSDGSIRLFERNSDYRTHLKKHIKMYKCPVPGCKNVEGFGRKDQLERHIRTTKHSSTAPGVQTPGNGPPHMAPAQPQPEFVPPMTHRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z033</accession>
    <name>A0ABR3Z033_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">GTPase Cdc42</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">cdc42</name>
        <name evidence="10" type="ORF">Cpir12675_003921</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000101">
        <property type="protein sequence ID" value="KAL1893853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01874">
        <property type="entry name" value="Cdc42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037874">
        <property type="entry name" value="Cdc42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1893853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="194" mass="21591" checksum="9C5FD6AB750DCD49" modified="2025-10-08" version="1">MVVPTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGDEPYTLGLFDTAGQEDYDRLRPLSYPQSDVFLVCFSVTSPASFENVREKWFPEVHHHCPGVPCLVVGTQVDLRNDSSVRSKLAKQDREPVKREDAETMAKNLGAVKYVECSALTQYKLKDVFDEAIVAALEPPTPKKRQHKCAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0C1</accession>
    <name>A0ABR3Z0C1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein GLC8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003853</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000098">
        <property type="protein sequence ID" value="KAL1894069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1050">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007062">
        <property type="entry name" value="PPI-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12398:SF20">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY INHIBITOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12398">
        <property type="entry name" value="PROTEIN PHOSPHATASE INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04979">
        <property type="entry name" value="IPP-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="228" mass="25154" checksum="0D47F4206E206865" modified="2025-10-08" version="1">MPSHVQTSTIVDAQMPKGILKNASAGGTLPSPPPVAVAVAIEPPQTERELTQLNTQINSGSRRSSSAARHSISRRLSQPAENDENAPRLKWDEANLYLTEQERTAKMKIDEPKTPYARHYNPDDDPSDDEIPGMDLGEPEEAIPEIPPVPSPKAVHVDESMAIGHDDDELAGMSPEEREKHRKFEEMRKKHYEMKNVAALLAHAVEDDDEDDEELGDAPPPPMPALPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0E2</accession>
    <name>A0ABR3Z0E2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcriptional regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003834</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000097">
        <property type="protein sequence ID" value="KAL1894099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037647">
        <property type="entry name" value="HIRIP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15410">
        <property type="entry name" value="HIRA-INTERACTING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15410:SF2">
        <property type="entry name" value="HIRA-INTERACTING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="289"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="396" mass="43324" checksum="2085EC44796FD0A2" modified="2025-10-08" version="1">MASTDQAIEDAIHNTVASIWDKKGARDSLTVNGVRKAVEETLSLGSGFLTGDEWNRKSRNIIKELVEKLSKEDSESDEEPEEPATKSNGKNKRKTNADSRPSNKRAKKAKATAKSPKAPRKIASSEDESEAELSIAELSDNAEASDKNTTTPNAIHNSGNGMSGDESDLSSVIDEPPTRKRTSVAKAKSKPEPKPKPAPRKLPSPQSADQQEVKKLQQQLGKCGVRKIWGVELKAYGDDDRAKIQHLKNLLRDCGMTGRFSDARAKEIKEQRELMADLHDVQAMDQTWGASEAATGRTTRASRRAAPKSLKIHNQVIEGLSDESEGDDENGDSGEDEGMEKEKPKKKRAVSKKPESDDDDDDDDNDDYDDDDKISSDAISDGDESDEASNMSDDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0R9</accession>
    <name>A0ABR3Z0R9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TOR complex subunit lst8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">LST8</name>
        <name evidence="5" type="ORF">Cpir12675_003796</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat LST8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000096">
        <property type="protein sequence ID" value="KAL1894108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037588">
        <property type="entry name" value="MLST8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19842">
        <property type="entry name" value="G BETA-LIKE PROTEIN GBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19842:SF0">
        <property type="entry name" value="TARGET OF RAPAMYCIN COMPLEX SUBUNIT LST8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="71"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="112"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="203"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="256"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1894108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="317" mass="35339" checksum="4F49D06BEB556B5A" modified="2025-10-08" version="1">MSVILCTAGYDHTIRFWEALSGICSRTIQHPDSQVNRLCISPDKRFVAVASFARVELYDIKSTNPNPLLKFVGHTGNVTGVAFHCEGKWMVTSSEDGMVRIWETRNGVVQRTYMHGCPVNDVVIHPNQGEIISCDRSGSVRVWDLAENNCSHQLIPEEDTPMSSVTAASDGTLLCAGNTMGRVFVWQLIPGPERTELIPITQFQAHPTFITRILLSPDVKKLATCSADHTAKIWEVSQTEAVPGQEPQPFHQEATLTGHQRWVWDCAFSADSAYLVTACSDHYARLWELSSQQVIRQYNGHHRGAVCVALNDYSEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z109</accession>
    <name>A0ABR3Z109_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphatidylinositol N-acetylglucosaminyltransferase subunit H conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_003890</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PIGH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000100">
        <property type="protein sequence ID" value="KAL1893872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044215">
        <property type="entry name" value="PIG-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019328">
        <property type="entry name" value="PIGH-H_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15231">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15231:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10181">
        <property type="entry name" value="PIG-H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidylinositol N-acetylglucosaminyltransferase subunit H conserved" evidence="4">
        <location>
            <begin position="179"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="279" mass="29724" checksum="71F3B54870C1B17C" modified="2025-10-08" version="1">MLATTPYLTKRCPSPTTVEYTVSNRPRPSFSQHLKASALALLRALIIASVALILWGKWNQPDCSTGLFPSTSALSRVGYAAAATPFSSATTTALTAHLASALKISAAPLSARYTPGVSQRSCADVPVFTDWPLLLQAVNTLPFGTRVHWAVSRGPLAAVMVVCLAVMYTALLRVHAAESLLVLRGLGIQTSSVAAGSLLGAPASTRFIPTEKIQDVLVNEAFHGFEVGYYLLIVVDGEEDVVVVFPKLLPGKDVVTTVWRGVKACLYEGPPDGMKMREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1P2</accession>
    <name>A0ABR3Z1P2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Transketolase</fullName>
            <ecNumber evidence="4 10">2.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">TKL1</name>
        <name evidence="12" type="ORF">Cpir12675_003805</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:10508"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="10">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the transketolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.1" evidence="4 10"/>
    <dbReference type="EMBL" id="JAWDJO010000096">
        <property type="protein sequence ID" value="KAL1894117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004802">
        <property type="term" value="F:transketolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07033">
        <property type="entry name" value="TPP_PYR_DXS_TK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02012">
        <property type="entry name" value="TPP_TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055152">
        <property type="entry name" value="Transketolase-like_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005478">
        <property type="entry name" value="Transketolase_bac-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049557">
        <property type="entry name" value="Transketolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033247">
        <property type="entry name" value="Transketolase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00232">
        <property type="entry name" value="tktlase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522">
        <property type="entry name" value="TRANSKETOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522:SF2">
        <property type="entry name" value="TRANSKETOLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22613">
        <property type="entry name" value="Transketolase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="5 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="11">
        <location>
            <begin position="356"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1894117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="683" mass="73995" checksum="B738A1F368FEE319" modified="2025-10-08" version="1">MGFSDIDTLAINSIRVLAADATFNSNSGHPGAPMGMAPVAHVLFNNFMKFNPKNTRWLNRDRFVLSNGHGCMLQYALLHLFGYDLSIQDLKDFRKIDSKTPGHPEAHFTPGIEVTTGPLGQGVCNAVGLAMAQAHTAAVFNKQGFNLIDNYTYCFLGDGCLMEGVSSEASSMAGHLQLGNLICIWDDNHISIDGDTNVAFTEDVVKRYESYDWHVVTVENGDSDLAAIAAAIKECQAVKNKPSLIKLRTTIGYGSLLQGTHSVHGSPLKAEDIKQLKSKFGFNPEQSFSVPQEVYDYYAKHAAEGAATEQEWNALLAKYAEAYPTEHADLLRRQTGDLPTGWEKSLPTYTPADAAVASRKLSEIVLSKIEGVVPELVGGSADLTGSNLTRWKEAVDFQAPQTGLGNYSGRYIRYGVREHAMGAVMNGLAAYGTILPYGGTFLNFVSYAAGAVRLSALSHIRALWVATHDSIGLGEDGPTHQPIETLAHFRALPNCMVWRPADGNETSGAYYVALSNKTAPSIMALSRQNLPQLEGSSIEKAAKGGYVLSEVEGAQVTIVSTGSEVNICVDAAKVLAQQGIKARIVSMPCTEVFDQQSLDYRLSVLPDGIPAMSVEPMSTLGWEKYAHEQFGLNRFGASGPVKDVYKKFEFTPEGIAKRAAATVNFYKGSVVRSTLKHAFEQLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3D9</accession>
    <name>A0ABR3Z3D9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Rho GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RHO3</name>
        <name evidence="5" type="ORF">Cpir12675_003494</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000084">
        <property type="protein sequence ID" value="KAL1894800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0488">Methylation</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="133"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="148"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1894800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="249" mass="27178" checksum="667BB84604360D49" modified="2025-10-08" version="1">MPALCNSSKTVGRKLVLLGDGACGKTSLLNVFTRGYFPTVYEPTVFENYVHDIFVDYVHIELSLWDTAGQEEFDRLRSLSYDDTDLIMLCYSVDSKDSLENVESKWVGEIADNCPGTKLVLVALKCDLRESVDDEEADKDNGDQAPLGTAPGAATDGTTPATTTTTTTSTPASKTTVNATDSSTPLAKAEKKPTINYDQGLEVARRISALRYLECSAMRNRGVNEAFTEAARVALSVKRDTDDYKCVLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3G6</accession>
    <name>A0ABR3Z3G6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DNA polymerase alpha accessory factor Mcl1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">mcl1</name>
        <name evidence="10" type="ORF">Cpir12675_003339</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000077">
        <property type="protein sequence ID" value="KAL1895156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057646">
        <property type="entry name" value="WD40_WDHD1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022100">
        <property type="entry name" value="WDHD1/CFT4_beta-prop_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048591">
        <property type="entry name" value="WDHD1/CFT4_hel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19932">
        <property type="entry name" value="WD REPEAT AND HMG-BOX DNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19932:SF10">
        <property type="entry name" value="WD REPEAT AND HMG-BOX DNA-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20946">
        <property type="entry name" value="Ctf4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12341">
        <property type="entry name" value="Mcl1_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24817">
        <property type="entry name" value="WD40_WDHD1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="WDHD1 first WD40" evidence="9">
        <location>
            <begin position="16"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="234"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="WDHD1/CFT4 second beta-propeller" evidence="7">
        <location>
            <begin position="408"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="domain" description="WDHD1/CFT4 helical bundle" evidence="8">
        <location>
            <begin position="744"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="706"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="727"/>
            <end position="736"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1895156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="858" mass="95453" checksum="383AE99B18BF6C6C" modified="2025-10-08" version="1">MDFDRNMSGASRPRARPAYTKGTTRCDYNRDGSRLITAGVNPTLRLYKTGFDGEPTNIDECPQANLAVAAGDEYFYVGDEDGVVGIYTIDPPAFKEYLVRVTMPVRDVALSADQKWCAVASDELTVKLVHTEDHSKTRILREHNRPAKHVSLDPRGALAAVSCQDGIVYMYSLTSEQPELLKKLDGMIGSIDGESSGSSQVAWHPDGRAFAVPSPTRDIYMISKDDWQKHATFENGHSGMITAIAWSPNGSILASAGQDGKLLLWDAASQSIFQRFDFANVMHLSWHPVKNLLSFTTTEGEVYIYPDLVNDQYDALLKLPLQKSISNVIDPTNTASVALAARPRHFQADNGGDEFDLGDGSDMDDFVVDDDGAGYTTGRKRRADGELLGSGEYPPTKRRTLMQPNFHEPFQPGATPWRGNRKYLCLNLIGAVWTVDQDSHNTVTVEFYDRDFQRDFHFTDTFLYDKACLTGNGTLFSCPAKSETTATLFYRPHETWTQRNDWRTELPKGEDVVAMSLSDAFVSVVTTGGYVRIFTLFGLPFRVYRPKSMPAVTCASWKDYVMTVGNGPVGADGQARLLYSIENIKRDEVCQNEDIVALPSGASLRTIFFSDDGNPCIYDSTGVLLTLIHWRKPGRAYWVPLLDTNLLARLASGRKNETYFPIAVANERFHCIILKGGDRYPYFPRPLLSDFEFSVPLHSVADVRKKKKKDKAGSGSGIDNDLAANSDDGEDNEDDALGTSETRKLEHAFLLQNIQVAQLNDVVSTEAGSAAGRYALRSQLARTQTEVDKTLLQLLAIECREGEERGMKALELVQLFQDHTGRMLQAAVKIADRYERGLLGEKIREVAEKRETAMDEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z408</accession>
    <name>A0ABR3Z408_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">A-kinase anchor protein 7-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003423</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000080">
        <property type="protein sequence ID" value="KAL1895007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1140.10">
        <property type="entry name" value="Cyclic phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019510">
        <property type="entry name" value="AKAP7-like_phosphoesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009210">
        <property type="entry name" value="ASCC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13360">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13360:SF1">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10469">
        <property type="entry name" value="AKAP7_NLS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="A-kinase anchor protein 7-like phosphoesterase" evidence="1">
        <location>
            <begin position="12"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="250" mass="26883" checksum="0B3A98647B22FD8C" modified="2025-10-08" version="1">MAHRAAPQRLRPTHFLCIPLVTPTSWPQLQRSLDTFRQHVTATPALGVPPDAIRPLGTIHLTLGVMDLKTDANTLGHACEVLSGLQPRALLAAAHAELHGSPTPVAEGDGSPPPLVVSLTDLKPMHAVTSTSVLYAQPTDPHGVLQLFCLKIRQAFVDAGLMALGNQPELRLHATVVNTVYMSGQSRGHGSQRNRSKRISLDARQAVESFGGFRWASHVPVEAIAICRMGARVVDGVDGEAYMVEKEIPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4I9</accession>
    <name>A0ABR3Z4I9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Actin-related protein 2/3 complex subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ARC18</name>
        <name evidence="7" type="ORF">Cpir12675_003337</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the Arp2/3 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
            <location evidence="1 6">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ARPC3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000077">
        <property type="protein sequence ID" value="KAL1895154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1760.10">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007204">
        <property type="entry name" value="ARPC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036753">
        <property type="entry name" value="ARPC3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12391">
        <property type="entry name" value="ARP2/3 COMPLEX 21 KD SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04062">
        <property type="entry name" value="P21-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016315">
        <property type="entry name" value="ARP2/3_P21-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69060">
        <property type="entry name" value="Arp2/3 complex 21 kDa subunit ARPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR016315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="193" mass="21780" checksum="24C8826C6B10831F" modified="2025-10-08" version="1">MPAYNSAFNTDPNPPHLIGNFPLLPLRTKTRGPAYTLPFPTPALAPGEAPDVGSESYDILDEVLAVFRANTFFRNFEIQGPADRLLVYGIWFVSDCLGKIKPNHSVRDATKEVQNVSLDMNFAIPGDPGWPLNQMYEAPRDRQEAETLRLYMSQVRQELAARMLTRVYGDGVDGKPSKWWLSYTKRKFMGKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5D0</accession>
    <name>A0ABR3Z5D0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription factor CBF/NF-Y/archaeal histone domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_003173</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000071">
        <property type="protein sequence ID" value="KAL1895535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22906">
        <property type="entry name" value="HFD_DRAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050568">
        <property type="entry name" value="Transcr_DNA_Rep_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252:SF5">
        <property type="entry name" value="DR1-ASSOCIATED COREPRESSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252">
        <property type="entry name" value="HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="4">
        <location>
            <begin position="384"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="460"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="34"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="159"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="219"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="230"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="270"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="460"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="492"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="502" mass="55779" checksum="32512ACE6E68E8A8" modified="2025-10-08" version="1">MADPSRSSYAPHSPNLSHYPHSAGDSVHERYRYHPYQRQQSQQQQQQQQQQQSYYHQYPGQYQPQIASYTQQQPQSRQHHQQDEQQVPFQKYYPPEQQSSQARPVPAPAPAPEPQTRYHSSTMPLHPQHPQPTKNQPPHQAPAFLSTYQANAGSGSGPGSSYSSQVPSYTSNFAIPQNSATASYSSPSVAAPASPTSTYNRNHGPPPHQVAGQGTHLNSHPHPHPHPHSHSQSQPQPQAQPKPQAHPHLYQQPLSQQHQNQPQFHHQAPSSPTYDSSLQPSYTQQLQSQPRQLAGASSHSHPKPEDFQSASHAIHVPQQTTVPPIKVEERSLKSIASAQMPPRRAAAAAAAAAIKNDEDTEEEILTLPEPLHDAPIEPSPVKTKFPTARIKRIMQADEEVGKVAQQAPIAVGKALELFMVALVSKSADVARERGQKRITTAMMKQVIETDDQWDFLRDISAKVDTEEKPSRAGRAPKQEASDTEDENPEPKKRGRGRKKKIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6D5</accession>
    <name>A0ABR3Z6D5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000062">
        <property type="protein sequence ID" value="KAL1896213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="118" mass="11315" checksum="5F4E424AB792B7C8" modified="2025-10-08" version="1">MVFGLSHHHHNDKKEEGHHHGNHGGPPPQGGQGGPPSQGGPPSQGGHPSQGGHPSQGGPPSHGGRSGHGDFGGPQGQQNFGGPHGNQGGGPSQGNHGQHGSHHGGGGPGGPGGSGGRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6J2</accession>
    <name>A0ABR3Z6J2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ankyrin repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_002866</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000060">
        <property type="protein sequence ID" value="KAL1896273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="85"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="168"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="204"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1896273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="228" mass="25102" checksum="92C78F50C327B5DE" modified="2025-10-08" version="1">MANDEHDGASVQEQLIEACRRNNTELLEELLEAAGSDEEISRLLNTTTTVMGDYLYHVAAAQGHYDIIDMLLDQPAFECDPVNRAGNTPLHTAIQWLNSEPAAQRPFGNALIKMMLEAGSNWRLRTKAGLAAEQLADPSNSELREIIREHEYAEMNQGDFVDADSGATAAETNVETESRNVSNSHSVKPPPVPSKAAPSLPMESGDDGEFSGSDEEERAEWLRRKGHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7L9</accession>
    <name>A0ABR3Z7L9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BEN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000055">
        <property type="protein sequence ID" value="KAL1896663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="404"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="481"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="683"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="404"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="481"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="687"/>
            <end position="730"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="864" mass="94196" checksum="7454B32041B3C0B7" modified="2025-10-08" version="1">MDNQRRRHYFESPVPSNGNDNFSTRHSTEPIASASTSVHCIRHPSTWQAPFHLTAQLPSIHSLSSFNPVPRSDYECHSGTQLQSVYSCQSETQAQSQNLPSLPPHAQCGRSSSSTSPVAQDLTNSHQASFLVTSQAATPPSISAASTSPSLQYEVQAGSSIQPLPRIQLQPSQPVESTQPSQLQPLNMAPTATTIAPSTLSSVTSLTSCISRKTRPESISSITGIETPTNSVPDSSSLKIKPVPASQVVPATQLSPQNLDVQTTPKDTPRPIPQASSQASPQSFNPALFYSFPQFNPQSLPAGYPPNFMFAPVSGTYPQFLSQGLPQTFPHPFSINLGATLQEQNQQLSYLIGQQNSRPLNLTESSLATPEALALTIHSTASTSQSTVDSSAQQPLLQKAQQLSPLHNPQQQQQQQQTSTSPLKRSRLADDLAQGSAKRPKMSPALDNPLPPADPLMRGRMASALLALKPGLANHPMWNSVSTPTTVTSNSMDSTDSQVQTTPRSTKPLVPSLLSYQLPGNSVILQQQPGPEEIEQTNNDLKPSLQVPADLDSLSEIQIEALKTLWPHLFSSQTQLPHQQSQLPRQNATSSLPAANTAVLNSAARKLLLSYQDINNVQSLPQLDSIQSLQRQQQQRRALALSLEAAGPTPLPSLLQQASQYESQLLTSQASVNLAQSRISSQQNANQSLQRQLHQMRQLQRLRQMSQAQQQRQQLLSQQQMSLSHQSQAQPQPLKPHTDSVSEPTFVKHVIIDILDSIFETMPFDQISKRQSLSPQKVRAIFEAIVQVPMLRYPGDKRKVSKFALNKIREHHEAKKKMLETEYGGGATTNIVKGGDVEGQLPFALAKFMGESGPKDYPAGVPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7N0</accession>
    <name>A0ABR3Z7N0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Calcium-binding protein NCS-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ncs1</name>
        <name evidence="8" type="ORF">Cpir12675_002693</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the recoverin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000055">
        <property type="protein sequence ID" value="KAL1896671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028846">
        <property type="entry name" value="Recoverin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055">
        <property type="entry name" value="CALCIUM BINDING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055:SF178">
        <property type="entry name" value="NEUROCALCIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00450">
        <property type="entry name" value="RECOVERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0519">Myristate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="60"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="96"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="144"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1896671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="190" mass="22003" checksum="FF1AF52F6896CBD1" modified="2025-10-08" version="1">MGKSQSKLSQEQLVELQKSTNFDKKELQQWYKGFLKDCPSGTLTKEEFQKIYRQFFPFGDPSSFADYVFNVFDSDKSGTIDFKEFICALSVTSRGKMEDKLEWAFQLYDIDGDGRISYDEMLKIVEAIYKMVGSMVKLPEDEDTPEKRVRKIFRMMDKDENGSLDMAEFKEGSKRDETIVSALSLYDGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7N1</accession>
    <name>A0ABR3Z7N1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Hyphal anastamosis-8 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002915</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000062">
        <property type="protein sequence ID" value="KAL1896207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42069">
        <property type="entry name" value="HYPHAL ANASTAMOSIS-8 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42069:SF1">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="141"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="223"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="288"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="427"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="499" mass="55180" checksum="540DA873EBB30C66" modified="2025-10-08" version="1">MTQQEENKRPAALDLKPSRSLSSESSTSSLDSLKHPRTPRFVEATAVHSPIDGKSPFTDPKVADIGFGYIQNAPTQTTYLAPPMSPLKSALRSPTAPRRFADGPLSPTFREEQIRDKHEALTDKEQARDVKVKGRVRLAKFALRFVNFGCSLIILAMISSTLAIFNSTRSLPTQSSMPAWAKGTSTWPQIMVLTMACISLTACLIVFFAYCKGGHRRAEKVQTYYTMFAIGWFILSMILWAISAGIFQYKRNNSNNKDIWGWSCVDNKRSQVFSDKVDYALVCRLQNWALICMIIEIVVEVICIALYTFIFYRYYTKRRLRKTMDSRDKARSDMYLAQLRMQSAPNTPGFGPKSPALSNYAFSPRFAPATFASMNDIESQTSTKESPFTPGNRAAEPPSQFETSLKPALTTSPSVPFKLQAPPPKAPSATPKASNNGLSPITPTSPPFPTDVIHGSPAKPRTPSPPLLLPTVAPVTADEPVYESVPIPGAYAEGYTHAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7P4</accession>
    <name>A0ABR3Z7P4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Actin cytoskeleton and mitosis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SAC3_2</name>
        <name evidence="4" type="ORF">Cpir12675_002730</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000056">
        <property type="protein sequence ID" value="KAL1896634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045107">
        <property type="entry name" value="SAC3/GANP/THP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005062">
        <property type="entry name" value="SAC3/GANP/THP3_conserved"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436">
        <property type="entry name" value="80 KDA MCM3-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436:SF3">
        <property type="entry name" value="GERMINAL-CENTER ASSOCIATED NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03399">
        <property type="entry name" value="SAC3_GANP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAC3/GANP/THP3 conserved" evidence="3">
        <location>
            <begin position="304"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="719"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="902"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="958"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1185"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1362"/>
            <end position="1381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1461"/>
            <end position="1483"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1052"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1111"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="57"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="103"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="138"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="721"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="909"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1226"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1461"/>
            <end position="1472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1473"/>
            <end position="1483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1483" mass="160698" checksum="270C7666F9AC8C4D" modified="2025-10-08" version="1">MATFAGNGFGGTSQQSNSASQSPFSQPPIFGASSSALGGASAFGGGGPVGNPFKAGSQPTTASSNPFSSALTGAPSTSTVKNPFQTQLPPASPSSNPFLSTGAAAANTEISASATSTQAPTFGRASPFGVPSAPAGSPTPGFGTPNTTTTNVTTVFGTKPTWGQTKDAPFIQPTSAQTSTSFPPAPKPTFGFAATSHNEPPAPKLKAPLAHVQLGQNAEPMDVNNQYANRIYRQLMSDKIYPPIWPQNPSDPANKGAMANFREQYKTYRDKARASLVKNGLIDDPDTRRKLSEAIEFKGVCEDMCPEYEKVLRITEHDVKMAEKNLHSSFAQTDIMVKKLARSAAGQEAPLPMDVRSVPCIRRTLDYLLDDLMKTEENLPSTHGFLWDRTRAIRRDFAFFSSMTKDEMLGQIYCLETLTRFHVTALHILSGPGVAPEDFSEQQEVEQLGKALLSLIYAYDDCRNQGISCKNEPEFRAYYLVLRAFDTNILDVLESEWNIPTLIDSPIIQTALSISQSLKTPRDVRGPIRPGVGSITAPFCGFFDIIAGPTVSFTMACFAEIHFGRYRRAVLRGLNKAFARPRGHAKDIKADGINKHLRFDTVDECIEFVELHGLTFTPEAADAAVAGDRVLVAQYGQDLDHPRLKNAFSRTMVDKKRGSYPLPYVIRNAVYDTSMPSTANCTKGDIGRLAPQTSDFPFKTPALSSSMTNNSSIFKPAIPPHTTTPSPFGITPTSSSTFGTQTKSTKSTLPFGSKYSTNSLAGKVGTSDNLDNSSSMKQTTDQSPFSTNPSATTVASIPSLIPNQTIGLPPSFNFAAQSTPTSKVISDVPSTEKPISGPEKVAPAAASVLSAPMFPSALALPTTSTSSVFVSRASAVPSLTTATTTAVSSKSSETPVFSISSTASNTAQSSFTPSLSFTPTVRPNESSAATTLTASTPISTLNQSTSMLNSVAPSFSNAPSKPIAQSPALQPPLESSPFATGKPAVVEPPTPILSELDPSSKLALFSGSSIIPPTRPPINKAVVLDGFTRWYTLGDDGLLQQFYLYMTEEIVRQTFEEFVAEEERRREEAEAAKDLAQAIKLRTYNISIRYLNRWRVIARERRLEALRRSGRDQLRAYHEAQRKERRKAEADLRRKTEMEAVESDKVRMFHQVAEKSKQSLMRINGSLGMSDYDYNQDSIAREDDVGSVWSVPDAPSAREEPRPKKTKHKAKGPTSISTHLAPAAQRSESVASTFSAGGKTQSIMEQYALSRSASLHRSMPGSSFSYSQFARSQFSTPPAESPDKRISKVSDRWRLKAMGLTTMPDGSILPDHLAQQVLYQKKRYSELGSCGLDSASRLRRVSAAAADLDFDMRISRAKALLPTTPRSRSGPGISATASPGTAARVSSTRAIDALMADAHHRKRSADEALGLTEVDIDSGDNSMFGQQRTQEHKEAMSATKRILLEAQKMREELRNMREEIKEGADWLHDEASRLQSPTPERYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7R3</accession>
    <name>A0ABR3Z7R3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003145</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000070">
        <property type="protein sequence ID" value="KAL1895564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="370"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="535"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="587"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="313"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="371"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="504"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="557"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="608"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="626"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="741" mass="83712" checksum="CCCDC2DA24D5CAC9" modified="2025-10-08" version="1">MAPYDIRSMALENLPFVLVENDDRDQASFMTLEFQKNDMATEYRHHMLQQQQQPASNPQLNHDYDHDDVQDDIFAAQQPQSQEQPQDPGAPSHPVAEMQAAFSESLIEATHNPELNKPSLREFDPKVRRQRLIEQPKSEALPYTRWRYRPEQKQHELWKLMAQISFGVYLLLNGRSNSTDQVITILQGHIDDIDEFLEVSLEDLSEAARDLNSRIQHLCLPMENRQVFEKLLEDRNFRAELMSGSETIEHVIARTTLFLDQCDDDIFHGFNATRAFSNYLGSEADASWCQERPGVMGIYEAMVNNTDGWQKTFITLEEKAKELNELIVSLTQMVADMQRIAAEVSRRTWISIEPFTSPLQGQAAAHMSHISQASYASPPSSFSKDSQSVRSHGSTQPSVSRPTPSTSSISQHPVDGALTPPPDARFNAQLGLDDQLSAENESEPERETTTASPDNEAFLLQPSVYTPKVNERESPLSPPESHASPPPPQEPEMLLLSDKRYSKNHPPSSSSISASMSEANISRTSLRQRISLKGHAPNNIHIPPPQRQTSAPVNPYQRQQLQQMQQQQRISDSAFSASMEHQYYNQPTSSIHSDMSPGLTPPQLLIPSPQSEVQQSYHPVLASPHSPLQQRPHTSHNTPRFIPSTPQEPMPPFPARQRNVPSRVGSGSTLSVGTAMTYDTTNSGGTHNQVKKKKSKFGWLKKAFQLDEEEKAAFEARRQMNARNLYYEDRSAQFLDGRRIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8G7</accession>
    <name>A0ABR3Z8G7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Programmed cell death protein 2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003041</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000066">
        <property type="protein sequence ID" value="KAL1895819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007320">
        <property type="entry name" value="PDCD2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47524">
        <property type="entry name" value="20S RRNA ACCUMULATION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47524:SF1">
        <property type="entry name" value="20S RRNA ACCUMULATION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04194">
        <property type="entry name" value="PDCD2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Programmed cell death protein 2 C-terminal" evidence="2">
        <location>
            <begin position="288"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="168"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="413" mass="44580" checksum="BBF552A69FF11D1F" modified="2025-10-08" version="1">MKDYDSDSDIGSHDFTETDVLLGYAQKELGDDVISHLGGTPEWIDPSTPPSATIARCKVCNDMMALLLQLDAHLPDRFPGHDRRLFVFACRKPKCRRQTGSIRTLRSVRISQDAPAVIAPGGRKKDVEEKKPIETNKIVTSTGLGESLFGAKSLGGSAAGNPFGGGNPFAKPAAATATPKAEGEKESPSIAKSADTLPATFSKMLSINNPLANKPKTVPTPPEPWPTTLAKAYPVLYMDAEYETLDPEPEMKLPAHATIEKMEVEDATASSSSGGNKEDANAFESSMDATFQRFADRMAQNPDQIIRYEYAGVPLLYSDSDAVGKMLAVTGDIKGKGMPRCQNCGAGRTFEVQITPHAITELEADDMNLDGMDWGTIIVGVCEMDCQESLVEAGGVGYLEEWAGVQWEELNQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z958</accession>
    <name>A0ABR3Z958_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000054">
        <property type="protein sequence ID" value="KAL1896732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="17"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="195"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="306"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="383"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="433"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="493" mass="49931" checksum="9A9ED44429F53EF5" modified="2025-10-08" version="1">MAGPGTPSTEGPSFTPPPLPFGWIAQWDSSSKRYYYVQLSTGQSQWEVPTHAIPTGMTPHPIAEHPYGYPQPEIITFEDGSQSKRHADGTIEPVLPDGNSRPGDVATTKPVLSATGDRGIGSIAVNALLGQAKNSHANSSHSSSNSGGLGSLGSLAGQVIGGLSGGKTNSNNNHGNTSKLSGGKLAAQLAQGLFSSSGKTGGNSTNSHNPHNNHGSSSNGASPSSSNYHGGTTSGTPQSHGLGGLGGNILSGLVGGNKPSSTSNFGYSNASPNAAYNGEAPANSYQTAQNSTHGTHPQSGPPPATHYHQQPSHSSNSYHSPPAAGNNSYQAPPPVTAAYHNTHNHNTSGNPSYQGSASGSNYGSPPAVPSYNRPDSGPHSHHNSSPNHATYPGATAVGTSGAAGFGGSGGQSTYHHQSQPVSHHGGGAPPQPSSSGPSPYSNPGGYTHTQPHGQPAYGNHAPPPTQGYQHHNQYAPPPTTNYGAASGYGNPHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9Q6</accession>
    <name>A0ABR3Z9Q6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">tRNA-specific adenosine deaminase 2</fullName>
            <ecNumber evidence="3">3.5.4.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ADAT2</name>
        <name evidence="3" type="ORF">Cpir12675_002847</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.1" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000060">
        <property type="protein sequence ID" value="KAL1896254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004131">
        <property type="term" value="F:cytosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="105"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="167"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="345"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="167"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="187"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="474" mass="50704" checksum="6BAE480F0114AD99" modified="2025-10-08" version="1">MPISNGPALPVEDTPEFGFYVFQASLGSPLEFHPAQGTALLKEMIDVYGPGNTSIEEKTSSVQYPQLGLHGFFFRLTTAAHLELSFNPGQDCYCENTKAPNSWHEDLTKDGVDVTNSASRGSKTREQRSHAHMMRIVGACESCQRKKVRCDPKHRSSTSAAAINAITGSQAASSQSRKSLARKKAAAAKAAQKEAQASSQLSQSAQTVVPGVFEPSQPNIDDPISFLDAEFNNFDDIMNWGESAIPPKVLQDYEIFDKNLLSPNIDSSAGSPGVAFRPPSNPIALSGSNADTVVTTAANNRSDSLPTTQKTNTAYDSSNAFLSTATEYADLCLYSPSNSFSDEDGLAGPDTLLHKSSSQNGRHSHYSQHRGIRSAQETLVPPNILTVVPADIFHQASLSSVDSQLVSISPTGSTNASDVQVYHHIIVDDKVTETGSSSSVVVTASNSQHTLSSSEAPDTWASELSARCNPELYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA66</accession>
    <name>A0ABR3ZA66_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002278</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000043">
        <property type="protein sequence ID" value="KAL1897550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1897550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="290" mass="32999" checksum="D60CF69B1EDD3F3A" modified="2025-10-08" version="1">MSSSTHSSNSKWNYEIDISTGSDYGLPKPSDRTQDRLSLDEEDRLAIRLSTTQGKATNTGSISHDYRGVLEMWKAIVFAETEKEHDTAWVILREESDDQRVILLYLYRTYMPLRAQWAHCFIRGYPNFGICVTSGTEASNNNIKSYLLKGMSHLFRLAETSEEMMADQEADFTDRCVQDVTLTKRELVSKGAEGVPTKSNPKPGLIGNCDVDCLVSTELGIPYYHEIYQKLVSGETVSKWEVHQRWHLRESAADSPYWRILDPKIATSIRERLKNTAQPVPEQLAVRVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA96</accession>
    <name>A0ABR3ZA96_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Globin-sensor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002488</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000049">
        <property type="protein sequence ID" value="KAL1897167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="entry name" value="Globins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044398">
        <property type="entry name" value="Globin-sensor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42071:SF1">
        <property type="entry name" value="GLOBIN-SENSOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42071">
        <property type="entry name" value="PROTOGLOBIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11563">
        <property type="entry name" value="Protoglobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Globin-sensor" evidence="2">
        <location>
            <begin position="23"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="232"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="266" mass="30154" checksum="62F464AF10DFA432" modified="2025-10-08" version="1">MASRPRLPIKHIDRKELYTNLEVRIQYLHSFLDFSSRDIEALITGTKYIKALIPAIVNIVYKKLLSYDITAQAFMSRNTSSAENIDGSVSENSPQILHRKMFLRAYLQKLCSDPSQMEFWEYLDKVAMMHVGLGRAHPLHVEYIHLGATLAFINDIMTEAILSHPRLHIQRKMALIKALGKVIWIQNDLFAKWQVREAEEFRADEEDIVIEQEGYLNGKKILGGSDDDLESDSASPTSPKAATSCPFSGVRVSDQPPQPHATESKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAE9</accession>
    <name>A0ABR3ZAE9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ubiquitin-conjugating enzyme E2 35</fullName>
            <ecNumber evidence="6">2.3.2.23</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">UBC35</name>
        <name evidence="6" type="ORF">Cpir12675_002381</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000046">
        <property type="protein sequence ID" value="KAL1897277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23813">
        <property type="entry name" value="UBCc_UBE2N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="5">
        <location>
            <begin position="2"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="3">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1897277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="150" mass="16928" checksum="128588BA8EB52B3C" modified="2025-10-08" version="1">MALPKRIIKETERLMAEPVPGISAVPHEDNLRYFDVEIFGPSQSPYEGGVFKLELFLPDDYPMTPPKIRFLTKIFHPNVDKLGRICLDVLKNNWSPALQIRTILLSIQALLGAPNPDDPLAADVAKSWKEDEQAAIATAREWTQKYAKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAY4</accession>
    <name>A0ABR3ZAY4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Long-chain-alcohol oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_002451</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000048">
        <property type="protein sequence ID" value="KAL1897195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46056">
        <property type="entry name" value="LONG-CHAIN-ALCOHOL OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46056:SF12">
        <property type="entry name" value="LONG-CHAIN-ALCOHOL OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="207"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="5">
        <location>
            <begin position="256"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="7">
        <location>
            <begin position="533"/>
            <end position="701"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="728" mass="79071" checksum="0529009E320EC60B" modified="2025-10-08" version="1">MANLVPSPSDLPDPSPAVDSTLHYIIDAATLDVICALVDTVLPGIRVSTSEAETDGNANQDTETRESLVISRAEFDALYADAKKNRSHFSSKAELVEFLAEKPVDNGDIVNSVCRAIEGTGPKQAKKRQGLASRQRVFKSWNASYFSMKRQVSKAFLMLAQRSYLQNSTLYAKTIGFTPVPPHYVKTASYPFEFVQFDSSRPDVIHTDIVIVGSGPGGGVCAKILSEAGYDVTVVDKGFYYPSQNFPLSQAQGEHHLFENQGAVMSTSSKVTCIAGSCWGGGGTVNWGVSLRTQDYVRREWAEADKLPFYTSKDYDACMDAVWEAIGATTDYDKGPRGPILLEGAQKLGYKAEYLALNTGHDKTHYCGRCHLGCGSNSKQGPMTAWLPQAAKNGARFVEGFQVDRVLFGNDGKTAVGVEGVWKSRNRSAEDNAYTRANPIIGTNLHVHPASTVIGRFDREIIPWEGPIMSSIMTSLENQDGSGHGIKVEPSCSIPFTAFICLPWYTGTTHRMNLAKLPTLAPYVVFARERDPGSVTVDPLTGRPEVNYTPSPYDTHHILKGILATARIVYTQGAREIIVGIPNLPPFIRDDAEREDRSEPVYNGEETSLLGSNAPKTVAERADAAFEAWLNHVESVGINGAGTPWLTAHQMGTCRMSGIESKGVVDPAGRVYGYNSMYVADASILPSASGVNPMVSIMATALHISKGMVQRLQAEDDRTRKSCSSVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBW6</accession>
    <name>A0ABR3ZBW6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">gamma-glutamylcyclotransferase</fullName>
            <ecNumber evidence="1">4.3.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_002169</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.9" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000039">
        <property type="protein sequence ID" value="KAL1897824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.10">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017939">
        <property type="entry name" value="G-Glutamylcylcotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12935">
        <property type="entry name" value="GAMMA-GLUTAMYLCYCLOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12935:SF0">
        <property type="entry name" value="GAMMA-GLUTAMYLCYCLOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="312"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="184"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="389"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="194"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="206"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="235"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="394"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1897824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="411" mass="45549" checksum="AE2FE27407964FDE" modified="2025-10-08" version="1">MVMIPPISPERLASAQISTNTQGDDTKRGTHTELNTVLYLAFGSNLNYKIITQEKGAHPLGKINVTAPSLRLAFDLSGIPYLEPCFANTALRKLPKDPLPDPINPGPTLPPIRDPKKPVWDKGLIGTVYEITKEDYAKIMAKEGGGSGYVEILVPCIALPPSVSIPERPDPSVPRPFIARTLYQPDIPGDIPDFPTPPDIPNKPPKLSEKPNKDDCPNNSILARGKQRGAENPAEPDPSNPPLKPDPKRKWWLRLVTPHKRPNPEYAQASSRYLNLIVQGAKENELPTEYQAYLESFQPYTITTFRQKIGRAVMLVTALPTFLILMLAAKYVSDNNGKYPTWLAIASNIMFNIIWIMYDNVMKPLFGDGERTILASPPKAEKKVMREVVRNSDDTSALLGQNGTSDSKEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCV6</accession>
    <name>A0ABR3ZCV6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Conidiation-specific protein 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000036">
        <property type="protein sequence ID" value="KAL1898112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="106" mass="11180" checksum="F4AC224504A91F8C" modified="2025-10-08" version="1">MSSPPSSRIVPDPTSLSPAIPSPVQAAAPPMTGTSQATASASSEGVGAGGPRRRSSLFQSLIDQKHHPDVVERRLSLSDQHRTPGFFGKMWKNYVMGSPSDANPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDH1</accession>
    <name>A0ABR3ZDH1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cyclin-dependent kinase</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">LSK1</name>
        <name evidence="13" type="ORF">Cpir12675_001917</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000033">
        <property type="protein sequence ID" value="KAL1898372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004740">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07840">
        <property type="entry name" value="STKc_CDK9_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF546">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="735"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="484"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1154"/>
            <end position="1181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="139"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="227"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="313"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="382"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="424"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="484"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="552"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="565"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="632"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="685"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1165"/>
            <end position="1181"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="764"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1898372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1222" mass="138246" checksum="412D3C66B7BE29BC" modified="2025-10-08" version="1">MSGTIARDKEPEEKRPKTEANSRGSLPKDLKADILADSQLLPDHRSYDYNQSDPSESHHQLSHTQIEAGYSSSTRDRDRDRDRSRGRNSSKRRHRRPSPPINNTKTSASAAPSRQSRAYGGVGSAPSDSVLTAVSDSSKHRRSRSRSVSRSRDRRDSRRDRDSNRERVVSTSYHRTRSTDNARHRSGHANDEKSSALRGNHSPTVKRRRSRSPSPHSHRKRSKRERNRRDRDRDRERDRDRDRDRDRDRDRNRDRDRDRNRERERDRNRDRERDRDRDRARGRERGKDYPKEPDNDTKPPRRRRHDSIDSRQPRRSRSRSRSHSPIQKSNQANTADTISNNTAFQSSAPPPRSLEPDRRPRSRSRSPRESRSSLRRRSTSNSRERGRDRDRDRDRGRDRDRIFGDIERDKRHDWPDDDTERGNRKGRRERKRGKRAVPGDPLASGANSVEVNLAARLGRNDQSVSYADNHSEKSPLRGFISLKNGFSNISTEPNEPATTGQSSQSPLNGYYDNQKPTSPPHTTHLGPSHRGNFRPASAAFKSGRLISTSDLDASKLESTDRNSKLENPSTDGQNPLASEHSQENDKPHSQASADKASGAEEEGIYDEKPLGDSVNQSGPSSGHKFSFAFKPSKTSTTTIPNPEISQKFNASVVSKPEKQPPTGPSRTTDPRDRDAPPKNAPTGPASTRVSRASQQQQQPRPPRTRKIVKKFRKLLPKPQLPEHLANSQSVYYRKPGNESVVGSGTYGKVFKAMNVYTNKLVALKKIRMEGERDGFPVTAMREIKLLQYLRHLNVVSLLEVMVEKNECFMVFEYLSHDLTGILNHPSFKLKDAQKKDMSKQMFEGLDYLHARGVLHRDIKAANILVSKDGILKLADFGLARFYAKRHHLDYTNRVITIWYRPPELLLGDTKYSAMVDVWSAACVMVEIFCRQPIFPGDGTESNQLERIFSVMGTPTKDTWPSITELQWFQLLRPSFLRPSIFNSKYHDKVSPQALQLLAAMFQYDPNRRPSAAEVLNHPYFTEEEPASVQCTELQHLDGDWHEFDSKALRREARRVQESGLDITAGGARKADKQNSIHNEAVVHEDVIARDVCSGLADTIEVVSASGATSIDPDPPVDTIIPDADTCINPDTDPILAETTEPSLIIDKMQIDSTQTPLEKSAEPFLSSNESIPLPDRSNSSTNLASMVDQTVPALCSNSVNSDITNASSTRAESLGLDRAGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF30</accession>
    <name>A0ABR3ZF30_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_001498</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000024">
        <property type="protein sequence ID" value="KAL1899305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23954">
        <property type="entry name" value="AMO1_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041367">
        <property type="entry name" value="Znf-CCCH_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21099">
        <property type="entry name" value="RAD201"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21099:SF2">
        <property type="entry name" value="SI:CH211-113E8.11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18044">
        <property type="entry name" value="zf-CCCH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="27"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="156"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="286"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="185"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="286"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="317"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="348"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="399"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="431"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="486"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="528"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="542"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="699" mass="69834" checksum="50CFFC3A3A1DC6E0" modified="2025-10-08" version="1">MTLCRFYQTGTCRYGNSCKFEHPGANNNAGNDSNNRFSAFGSSSNANNGPDTDDNPYKLSRDAIEKDLTSETPQWILSAYGPGTNAPEQLWGGFPLEQSADEIRLYYLTSEQAGKQGEALEQIAKLYQEAQGRIRNAASNLDDVIRYINSSRDKHPNRVDIVAQGNSNSTSTSAPSLGSSSNNPFVSATTGSNASQNSAMLGGSSSVFGQPSNLGQNPSPFGQSSTFGEPSQPNGGSTFGQPSSLGGGGAFGKPSAFGAAGSNNTGTGGFGALNSSGPAFGQSGFGSSAGNTAAATGTAFGQPSTFGQKPAFGAPSFGKPGFGQPAFGAPAAPAASGGGIFGQASKPTQTSSGFGQTTQTSGSAFGQPSSLGQSGGSAFGQPSQLGQSGGSAFGQTSKLGQSNGSSFGQSSQLGGGSSAFGQPSQIGAKLSAFGSSPAPTGGSTSGSGFGAFASKSGSGGSPFGQPSGNNANAATNSPFGGGGSTSTGSPFGQASASTSNPFGSTSSNSSAFGQAAPVKPNPFGAPANSANGSAFGQPSNLGANSSFSTANSSNGNTASSTSGFGQASSAPANPFGVPPAPAAPAKTNDPYPPNSGKQHPPVEMYTTRNSQTQQLAIFKGRPVEYVSDVPGIRDSGSGVWRKILFPNGPPINYPATEISLDKMEATVKQQWEHFATSGSFAGGKIPMQPPPRVACTWDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF43</accession>
    <name>A0ABR3ZF43_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cnl2/NKP2 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_001802</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000030">
        <property type="protein sequence ID" value="KAL1898695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018565">
        <property type="entry name" value="Nkp2/Cnl2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28064">
        <property type="entry name" value="INNER KINETOCHORE SUBUNIT NKP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28064:SF1">
        <property type="entry name" value="INNER KINETOCHORE SUBUNIT NKP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09447">
        <property type="entry name" value="Cnl2_NKP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1898695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="192" mass="20533" checksum="93D6D3989E189A4E" modified="2025-10-08" version="1">MPPTESSILSKYLLLPSTLPAIVSLADFASMFPKAQQASPHIRTLYHDLQEQRAELIDAVAANIEEEVARGRELRRAVARQRRQIEADEGDDEIAVEQALLGPVSDPASASVGAAATATHSLSSIIPDMDAAMNAVDTELQSLQAEEEALLEAVRQTVGSLSDLRYGRLANADLRDEVVDGLKAVETACGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF61</accession>
    <name>A0ABR3ZF61_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ketoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_001813</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000030">
        <property type="protein sequence ID" value="KAL1898706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF133">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="4">
        <location>
            <begin position="9"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1898706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="268" mass="27752" checksum="E17495E9460B095A" modified="2025-10-08" version="1">MSIQSLAGKHAVITGATGALGFAIAKHFISAGIARITLLGRRIDALNQASLALSQVPHSGVFKRTEGVAGSPDVQIRVHAVDVAKSEALKEAARQITTVPTHFLVNAAGIAQNSLLMRAPEEDLLAIVNTNLVGTMLACKYFSRGLARASDGGDSCIINISSLLALLGGRGASAYAASKAGVLGLTRSLSMELGSQGVRVNALVPGYIESKMVSDIFTKTPTPLIQSIPLKRLGTVDEAAHAALFLVQNKYANNCVLNLDGGLSAGIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFB0</accession>
    <name>A0ABR3ZFB0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001605</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000026">
        <property type="protein sequence ID" value="KAL1899049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050471">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433:SF10">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433">
        <property type="entry name" value="HYDROLASE, ALPHA/BETA FOLD FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="644"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="341"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="770"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="376"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="530"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="780"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="812"/>
            <end position="825"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="995" mass="108110" checksum="5A44A93A4D0A2332" modified="2025-10-08" version="1">MMDYTIPALPPIPKQTRQHSRQKSLQKALGRIQTSTSHPDGCQTPQRQLQKSHLQQNDQDKGQDQHLHQRQRLHQHLHQRLHQHQHHAPVPPASPEVLNSLISSFAVIQKPSSASLDIPSHTLRPPPPPAIPIASLSAPLIAPAPYRDGGSFGVDYGAFHQPSLENLRADKTSPPDLAAAPPVIKTSKPPSGYSSLTAPRGLVHRDSSGGLKALLRSNSRPSSKSSSCSRDDGNQSIGNISIDCSAAAAASIELRRSRSSDSWGRKQGRNQKGLMYMSSKEQLREKEYEKKRASLGTSGGSVDPNSPTLRSTALLAEIPITEEHADIPALSIAPENTANSTANTTMLGSHRVSPGIDGVSPHQIPIRDSSLRKTGSSGVRRSSARNSRSSKRDSSSGPPHDEDVIPEHSEPARHRSDVPLERRHRRGVSSLDAGISRRQTPDNYYAAGQSPPMGPLASRSHTPVHRHVSDSYRPPRNGLGGIAADDLDDEEGGAPSPAVAQGRRRDDSSDRTSKRRSGRYSSDAFDGVKLKRSSSRLKRLSGSGSSSPKPDKAEKKRLSSQGLLPEPSRFSTGYERPQSADSIDDAVESYLCSPRLSQKIRHPQTGRVISFSEVGDSEGCAVFFCVGMGLTRYVTAFYDELALTLKLRLITPDRPGVGDSEPYSDGTTTPLSWPDDVYAICQALKISNFSILAHSTGAIYALATALRMPQHICGRIHLLAPWIPPSQMNVFGNSQALPPTNAIPTSQRILRALPTPFLKAANSSFMTATSSSITSSLPKTPRRKRKSSSQHRSASLTANQDKENIGFPQGSKPLSDSYPSMTATENMDRVKPGLVGASGSRAPETNILNAAFDALSDKERQKIYDERLTYAIWQLATTGANPAVDLLVCLERRHTIGFRYVDITRPIVIHHGSRDTRVPIDNVRWLGKTLRRCEVRVLEGESHSLMASATVMGSVLMEISKEWDDWIRASGPGSSSGGPILIPLPPRSARVGILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFP7</accession>
    <name>A0ABR3ZFP7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Histone acetyltransferase type B subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">HAT2</name>
        <name evidence="9" type="ORF">Cpir12675_001914</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000033">
        <property type="protein sequence ID" value="KAL1898369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022052">
        <property type="entry name" value="Histone-bd_RBBP4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050459">
        <property type="entry name" value="WD_repeat_RBAP46/RBAP48/MSI1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22850">
        <property type="entry name" value="WD40 REPEAT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12265">
        <property type="entry name" value="CAF1C_H4-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Histone-binding protein RBBP4-like N-terminal" evidence="8">
        <location>
            <begin position="30"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="186"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="283"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="327"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="384"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1898369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="436" mass="48836" checksum="79725B1555E51B9C" modified="2025-10-08" version="1">MSSPSASLDNHTANLSIEEQEQEAQRVINEEYKTWKKNSPFLYDMVLSTALEWPTLTVEWFPDVKEEKDKPYNTHRLLIGTHTSNDVQNQVQIAEVQIPKVTTPNAEEYDEEKEEIGGYGKRTGGPGMKFNVVHRINHPGEVNKARINPLNPDQIATMAIDGRVLIFDRSKLSVIPGASLEAHMELHGHEGEGFGLCWSPHELGQLASGSEDKTMCLWDLNDYTTGNSILSPKRRYTHHDNIVNDVQFHPVVKSFIGTVSDDLTLKIVDLREASNSRAALVAKDGHVDAINALAWNPHQEVLVATASGDKTIGLWDIRNVKQKVHTFTGHEDAVTSLQWHPTEAGILGSGSYDRRILFWDLSRIGDEQLPEDAEDGPPELLFMHGGHTNHLADFSWNKNEPWLVASAAEDNLLQVWKVASQLITRDEGNIPLEDME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG07</accession>
    <name>A0ABR3ZG07_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CUE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001497</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000024">
        <property type="protein sequence ID" value="KAL1899304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14364">
        <property type="entry name" value="CUE_ASCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052586">
        <property type="entry name" value="ASCC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041800">
        <property type="entry name" value="ASCC2_CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003892">
        <property type="entry name" value="CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21494:SF0">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21494">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 2 ASC-1 COMPLEX SUBUNIT P100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02845">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00546">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51140">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CUE" evidence="2">
        <location>
            <begin position="338"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="614"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="677"/>
            <end position="694"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="694" mass="74752" checksum="2BE0B9AFF0ECD410" modified="2025-10-08" version="1">MDALPEFAPFPSCQVREALLPKQWANALAAWTTLTSAVLALSDDDLKDYLGASGAISAVAYLGSAYAEVAAKGPRILGSSPAKATANLRLMRTLLVRLLTKGQLAGLGDWGLLADFARVDWANAGDVLALAWTTQTSSIETSLAVLKKNLIRLLDASLSGDLKAVEQILSRLNYLLQGATIAAAYFAAGDDFMDGIVSCYKVMNPPLRKILLATGYLCLRGLLHSPEPKLGMLADRLYSLKVVADAHKAGPVSERDSYVVELVSATPILSQIKQVVESGNAPGTAALANRIDALKTYQRLGGARSLRPARLKQKKALDKGKQNVDKTADVNQVELHAHKLSKVAEIQDLFPHLGSAFVCKCLDEYGEDVEQVVAHLLDGSLSSYLTGLNQSERLYVHYLNYVIKVQLCSNANMRASRPDNGFVQTHIETAPQSTFDSPYAASALLPTRRNIHDDDDLDRLSTSVSKNLHFGKSNSRQTADSLLYDKSTAPSKAAIMSALAAFDADDDERDDTYDADNVGAAIDSTVNEADGIGLGNGNEETLWRVYTESPGVLDRSNDVRSSTARAKLREETAMTDEAIEGWYIMLNHSTRLKRNLEARYSTFDGSQTKLASFRWSRPTENSDSEDAAGPSNVGRGRGGYRGRGRGGGRGGGSVSGSVGDAATQKARKNKEASKGSRANHSRRDAHAKKMARGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG38</accession>
    <name>A0ABR3ZG38_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein mS41</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">FYV4</name>
        <name evidence="6" type="ORF">Cpir12675_001577</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mS41 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000026">
        <property type="protein sequence ID" value="KAL1899021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09487">
        <property type="entry name" value="SAM_superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039603">
        <property type="entry name" value="Ribosomal_mS41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019083">
        <property type="entry name" value="SAM_Ribosomal_mS41"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28235">
        <property type="entry name" value="PROTEIN FYV4, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28235:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09597">
        <property type="entry name" value="SAM_Ribosomal_mS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01238">
        <property type="entry name" value="IGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small ribosomal subunit protein mS41 SAM" evidence="5">
        <location>
            <begin position="72"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="248" mass="27454" checksum="0DC0421997FD0F7C" modified="2025-10-08" version="1">MASLRLPRFFASASFRPVPASIPASAHITSATVRQLHASQASCNIPQTSAASLSAPGSSSRVPAPIPLIPDVPTFLRAIGRDLVQYADKFPSWEALFTLSSEQLRELGVEPARSRKYLLQWLQRYRNGELGPGGDFKYVEDGKATLVVDHDLGTDVKKVVNVPYGKTIEEAGAEKVRVRGYSVKGAQTISGPYALPSGRETATMTVVDRMWEFRQGQKVDGGERRKTEIRFKRRIAERRARREAEEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGY1</accession>
    <name>A0ABR3ZGY1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein sym1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_001609</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000026">
        <property type="protein sequence ID" value="KAL1899053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF50">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEIN YOR292C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="240" mass="26366" checksum="C9DD256F755420B2" modified="2025-10-08" version="1">MALIKFAVGMFNEQYAKAPLLTTIAVNGLLGGIADTVAQTLTAVKTNYKHKQWVKAHGEPAPIASEVDIELDEKTLMAWKQAVLPRAPVPAQPFDPERLLRFVGYGVAMAPVQFGWFKLLGKAFPITKTAAMGPALKRMVCDQLVFAPFGVAAFFTAMTLAEGGRKAAVKKKLQDMYLPTLKTNWFVWPAVQIINFRFMPVHFQLPFVSTVGIAWTAYLSLTNAAEDVEIVSHLPSTISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH64</accession>
    <name>A0ABR3ZH64_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ADP-ribosylation factor GTPase-activating protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_001052</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">GTPase-activating protein for the ADP ribosylation factor family.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000015">
        <property type="protein sequence ID" value="KAL1900053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08204">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07608">
        <property type="entry name" value="BAR_ArfGAP_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045258">
        <property type="entry name" value="ACAP1/2/3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23180:SF160">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN EFFECTOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23180">
        <property type="entry name" value="CENTAURIN/ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16746">
        <property type="entry name" value="BAR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PH" evidence="7">
        <location>
            <begin position="642"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="domain" description="Arf-GAP" evidence="8">
        <location>
            <begin position="818"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="540"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1059"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="551"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="589"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1059"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1079"/>
            <end position="1088"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU369028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1106" mass="122792" checksum="25BF9AE7C91654E4" modified="2025-10-08" version="1">MGNVSSRLDTQAALFFKDQNRLFIPSVSITSPRKHSNIQISPNSFPASRFLASRPTGDTTPVEFIQEGDVSSASPAQPPSFLLKLSSDEELVFNFKFTIRRSDDGTSSPIDTNIAGLTFVHGSNPRDVENTLTSEFHSNPNLHKMDNVTLIGDYGTNGSPAVAFEWTWKWQPPKAMDERQAGWRNTCSFVEYDSRAHRLETLASFSFWVANDSRQSISQPTSPIPFFMSVPPKVRVVSAQTFDSRLSSSNDIDEPTSPMIPHLNPTPSSSVTTISPPQFIGTPSLATPVKIDIVCPKPDSELIASDDGPVFRATMKSLEQKTGNMRTQMKKVLKKAESAHASQTEANIAFESFIQSLHEASKTNMNAVKPAIDNFFDKISQEILKYETQNMENLKEIVIEPITRLYTSDIKQAEFKKRDFEDESKDYYAYVSRYLGQRQDSVKSKKLAESDNKYQSKRRNFELKRFDYSSFMQDLHGGRKDQEVLSQLTRFAKLQAESFVNTSKRIESLMPHLEALRQEVQQADNEYYLHKIEREEKRRVLETRGPISDTGIASANTNPLGSTNGQSALSDSELGRADSTSSQLRPILGSGSTVESSGLSSPANNSKFKGIRDLEDRNHIMLNTSSSPAGSSQRKEGLVWALSRPNGHVDPRAALKQSNWHKFWLVLDQGKLQEYSNWKEKLDLHMDPIDLRTASVREARNAERRFCFEVITPNLRRVYQATSEEDMNSWIVSINNALQSAMEGRGVRDIKPSPVVESSSFKRDIGKILTGKTGSLHGLHSNYQAISNSAGIPTRRTTVGARPSTARTNTSSYDENPDRLLQMLRENDQGNAWCADCGSGTKVEWVSINLAIILCIECSGIHRSLGTHISKVRSLTLDITSFTPDIIELLMQVGNRVANMVWEARLDTALKCSPQATREQRLRFITAKYVNREYVTPISPTLSRYATADETLLAAVKKNDIQQVIYALALKANPNLADRSRGTPVVILAMAAANPASPASTGLTKSVATVAEPEKTATFPVAEVLFQNGALVPMSAPAFPLSRSAQAYLDLKRGRANLLTSTSPEAGQTLTSSPSTLERMQRDKEARVQKRLSAGGRLAKSPIPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHR6</accession>
    <name>A0ABR3ZHR6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Serine/threonine kinase</fullName>
            <ecNumber evidence="9">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PKC1_2</name>
        <name evidence="9" type="ORF">Cpir12675_001484</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000023">
        <property type="protein sequence ID" value="KAL1899368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05578">
        <property type="entry name" value="STKc_Yank1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24355">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24355:SF30">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 32B ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="20"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="368"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="510"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="383"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="411"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="443"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="530"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="540"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1899368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="557" mass="62519" checksum="5C2478921A6D3454" modified="2025-10-08" version="1">MGNSQGKPVDLDGQVSLNHFRLLRVVGRGAFGKVRIVERKDTGLSFALKYIRKDEIIRSESVRNIIRERRMLEHVNHPFICNLRYSFQDIEYMYLVVDLMTGGDLRFHISRKTFTEEAVRFWIAELGCALRYVHSQGIIHRDIKPDNVLLDADGHVHLTDFNVATDVVPGRLIASRSGTLAYLGPEVYAGKGYDVRADWWSLGVVFYECIYNKRPFEGSSEQSLSQSIQAGRPRFPITQPPVSVPCMYAIMAALDVNPDTRLGSTWESFTQHEFFQAIDFVALEQKFLEPIFVPSSEKTNFDATYDLEELLLEEAPLEARARRQKPRERLKEDATDKEIREDELYRMIESEFKNFDYTVAALRKLGMDSPGNSHPDGMRACPVSTNNPSQGMALTTDETVYVPTSKENSHTRSYTRSQTQNSSHSPPTTYQQHMVDASQQMPGSSAQSTRSASGSFSKSGSRPPPVVSNNEIMRKNLAGRRIQSSTGGVQVTLDSHGSWSTLARQDATLPADAGGHEKDKENGGVFGFFSRKKGRSHSPKPRERGVLGKEGARQIIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHW0</accession>
    <name>A0ABR3ZHW0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase</fullName>
            <ecNumber evidence="4 12">5.3.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 12">5-proFAR isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 12">Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">HIS6</name>
        <name evidence="13" type="ORF">Cpir12675_001243</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:15469"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="5.3.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 4/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the HisA/HisF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.16" evidence="4 12"/>
    <dbReference type="EMBL" id="JAWDJO010000018">
        <property type="protein sequence ID" value="KAL1899744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003949">
        <property type="term" value="F:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04723">
        <property type="entry name" value="HisA_HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011858">
        <property type="entry name" value="His6/HISN3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044524">
        <property type="entry name" value="Isoase_HisA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02129">
        <property type="entry name" value="hisA_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43090">
        <property type="entry name" value="1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO)METHYLIDENEAMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43090:SF2">
        <property type="entry name" value="1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO)METHYLIDENEAMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="8 12 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1899744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="258" mass="28050" checksum="B7022138C0591C9B" modified="2025-10-08" version="1">MTRFRPCIDLHAGQVKQIVGGTLDSSTSSLQTNFVSPHPPAYFSKLYRDNKLNGAHVIMLGPGNTEAAKEALAAWRGGLQVGGGISDKNAAEWIDSGAEKVIITSYLFPEGKFSQARLDAVLAALKNDKSKLVIDLSCRRTREDGWHVAMNKWQALTDMEVNQESISALEPYCSEFLIHAADNEGLQKGVDEALVQRLSEWCSIPVTYAGGGRNLNDLELVKRLSAGKVDLTIGSALDCFGGSGVKLEECITWNHAQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIR5</accession>
    <name>A0ABR3ZIR5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001172</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000017">
        <property type="protein sequence ID" value="KAL1899951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="222" mass="24290" checksum="F02ED3745B93DE71" modified="2025-10-08" version="1">MSSPEAEPESSDMASLMGFASFGNAPRPAKRPRNDFTVIDGVASQATLFMPTHGTNANAIELGSSSRHESSGIDPAIAPATGDAAPRPSPLEALPASLPARPPPSIAETGPRPSFGMASSLNQNQGQYACGKIDSKRHDSDTRRQALRGDGPSRQRNSLWYIDYYDPMSNENPWEELEKRKGLEPLGVWLPRGHARQQPREAERTDRKEDGLKLEKQTEQEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJH1</accession>
    <name>A0ABR3ZJH1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Histone deacetylase</fullName>
            <ecNumber evidence="3 10">3.5.1.98</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">HDA1</name>
        <name evidence="14" type="ORF">Cpir12675_000734</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate</text>
            <dbReference type="Rhea" id="RHEA:58196"/>
            <dbReference type="Rhea" id="RHEA-COMP:9845"/>
            <dbReference type="Rhea" id="RHEA-COMP:11338"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="3.5.1.98"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the histone deacetylase family. HD type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="3 10"/>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141221">
        <property type="term" value="F:histone deacetylase activity, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019154">
        <property type="entry name" value="Arb2-like_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017321">
        <property type="entry name" value="Hist_deAcase_II_yeast"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF5">
        <property type="entry name" value="HISTONE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09757">
        <property type="entry name" value="Arb2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037919">
        <property type="entry name" value="HDAC_II_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5 10 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0678">Repressor</keyword>
    <keyword evidence="8 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 10" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="12">
        <location>
            <begin position="101"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="Arb2-like" evidence="13">
        <location>
            <begin position="479"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR037919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF09757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1900858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="753" mass="85073" checksum="076A2E29FD6F6500" modified="2025-10-08" version="1">MTSKPRKGSVMNNYVKGDVDHPMSMGDEPASTSNGYSRQTSRETTDFDSTTDSAVNDDDLTLLVGSSLKQVVRRGLLPTGCCYDDRMKLHVNADWSPHPHHPEDPRRIEEIFNTFKKNGLIYTGPPERLPEILRDNPTRYMWRIPAREARQDEILLAHQPAHYAFVKSLTSKSYAELRRLTKEMDQGRTSLYVGSMSYYAALLSAGGAIETLKHVVEGRLRNAFAVIRPPGHHAEKDEPMGFCFFNNVPVAVRLCQMDYPETCRKVMILDWDVHHGNGIQNIFYEDPNVLYVSLHVYENGSFYPGKPKDGVPDGGLSNCGRGPGIGRNVNIGWHSQGMGDGEYMIAFQRIIMPIAREFNPDLVVISAGFDAADGDELGGCFVTPACYAHMTHMLMSLAEGKVAVCLEGGYNLKAISISALSVARTLMGDPPPRIEIPRINKEASRVLAKVQSYQAQYWDCMRPGIVNIRDDVSKLNASRLHDVVRNHQRQDLQQKHQMVPLYIHRENMSHVFENQVLVTPRLSDAKRLLFIIHDPPQLLAQPGVDDSIIESHNAWMVDELAQYIDWAIENGFGVMDINIPGYIAKDNEQQEAFMPRVAERVLESEMNDLVCYIWDNYLQLYDQCDEIFLMGVGNAYLGIRTLLTGRADCKERISGVVNFVTGTLKAVKSDVDEGLSAWYKENSRIYVGADHACWNDEMLKRKVTKRRFGTVIESKMNGLNHMLHEHAKEAQEWIMERVEVAGETTEDDNMLQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJJ9</accession>
    <name>A0ABR3ZJJ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MRH4_1</name>
        <name evidence="11" type="ORF">Cpir12675_000702</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47960">
        <property type="entry name" value="DEAD-BOX ATP-DEPENDENT RNA HELICASE 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="178"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="440"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="77"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1900826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="595" mass="66275" checksum="169B2D1DCBFD5C63" modified="2025-10-08" version="1">MPIVISNRLSAAAFLPGVSSTTIVAGSTRGYAFGRRTVPSRMVLSKSVDRPPMKAGKMNKRMVEGPFGSMNQTVARLPSKAARVERHRRQDDERHDRKQREYYRRDDRKALKMQQSLSTMPYSRRNDIKDRMVKFESFDQFDLLPQVRSAIFSDALRGLVDIKPTPAQRLAIPAILSHSKAKTRREYLIAAETGSGKTLAYMVPAINALKIAESEDLEIADYKERQRVATESVKDNKSAAPFDEPHPTMARPKVVVLVPTAELVDQVGNVAKALAHEAKFKTEKLSSQLSPLVIHRNLYSPRGVDLIVTTPHLLASIVKSDPNVLARVTDLIIDEADSLFDRSFTPITTTILEKSLPSVKRLVVCSATIPKRLDKYLGEHYPDMIRITTPNLHAIPRRVQLGVIDVSRDPYRNNKDLACADAIYSIGRDAMRNQETGSAGSKDGALEVRRIMVFVNEREKTEELAGYLKSKGIKAVALNRDTIEQRYQAEALNEFTTSNPIRIPESLAGIKAGKSLPNVKVIVATDLMSRGIDTVAVRHVILYDVPHTTIDFVHRLGRAGRMGRRGRGVVLVGNDDRKDVVAEVKNSMFMGQALI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK97</accession>
    <name>A0ABR3ZK97_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Protein HIR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">HIR1</name>
        <name evidence="16" type="ORF">Cpir12675_000935</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 12">Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the WD repeat HIR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055410">
        <property type="entry name" value="Beta-prop_CAF1B_HIR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031120">
        <property type="entry name" value="HIR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011494">
        <property type="entry name" value="HIRA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019015">
        <property type="entry name" value="HIRA_B_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13831">
        <property type="entry name" value="MEMBER OF THE HIR1 FAMILY OF WD-REPEAT PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13831:SF0">
        <property type="entry name" value="PROTEIN HIRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24105">
        <property type="entry name" value="Beta-prop_CAF1B_HIR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07569">
        <property type="entry name" value="Hira"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09453">
        <property type="entry name" value="HIRA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="10 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0678">Repressor</keyword>
    <keyword evidence="9 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="8 12" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5 11 12" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="CAF1B/HIR1 beta-propeller" evidence="15">
        <location>
            <begin position="28"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="66"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="125"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="167"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Protein HIRA-like C-terminal" evidence="14">
        <location>
            <begin position="743"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="434"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="450"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="479"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF24105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1900465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1066" mass="115717" checksum="CBA5DE653C68FD0E" modified="2025-10-08" version="1">MHIIKPAWLSHSGEQKDFEVYSCHVSPDGKRLATAGGDGHVRIWSTEAIYNANNDSYTKPRQLCHMSHHLGTIHSVRFSPNGKYLASGADDKIICVYHLDKSAPSAAFGSSEPPPVENWKTYKRLIGHDNDVQDLAWSNDSSILLSVGLDSKVVVWSGHTFEKLKTISTHTSHVKGICFDPANKYLATASDDRTIKIFRFTSPAPNATQHDMVNNFVLESTISTPFRNSPLSTYFRRCSWSPDGNHISASNAVNGPVSSIVIIDRTSWSSDIHLIGHEAPSEVCMFSPRLFYNEDPAKVPNTSLVTVIASAGQDKTLTIWNTNNSRPVVILQDITGKSIVDLSWAPDGQTIFAASLDGSIIGFKFDAGELGWVATEEENYKALHRYGVSRKGMGIAEDVDGLHLENSSKQDESRAAQSRMGALMGDAASAIKEEEAVPQTNGVKNGISKPTNTTTTTAPGASGAAAAVTTTTNGTTPDLSKEKSKPEEPTQEQESAEKAAARVNELKSRVTVGKDGKKRVAPLLVSSSGTGLSSLPQAQLVGSTTAKAAPNDAPQTIIDISKPYDGLPKGGLVSLIIGSKRKAAIIETEDTHEDTPQRAASDPVPVVANGPDGVEAVQPTAPADGLVPVPDYLRSAVLNPAVSYSHLRLAVPKVRSLILRPLEKGILLGESTLEDATRLGENIILEAKNPTNAREPTRVVASKRAEVLWEDFLPRAVLLVAGNRNFWAVACEDGSVHVWTPAGRRLLNPMILESQPVILECRDYWLLCITAVGLCYVWDIRSQSSPNPPVSLGPVLEIAATSLSRHGFVTAPGVTSAHLNSSGHIIITLSNGDGYYYSREMFVWQRLSESWWAVGSQYWNSNDSSISALQSTAIGPKSESSSGKKRAKKINASTGVIPFLERHTTTEFLVKGRAYNLQRIIKLVMAKDGFQNFESSVSIAHLETRIAGSMTLEAQDEFRLYLFMYAKRIGAEGHRGKVEELLNSLVGGVMRDMQSDDVPAKGWFTKDGPICGWDRMELLKGVVMILGKFREVQRLTVQYAKLINLTNNGSGDDEDDVMDVDVVTGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKN3</accession>
    <name>A0ABR3ZKN3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PRE2</name>
        <name evidence="10" type="ORF">Cpir12675_000765</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the proteasome complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peptidase T1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03761">
        <property type="entry name" value="proteasome_beta_type_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000243">
        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF3">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6 9 10" id="KW-0647">Proteasome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0888">Threonine protease</keyword>
    <keyword evidence="7" id="KW-0865">Zymogen</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1900752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="287" mass="31415" checksum="45843ABD5767B0F6" modified="2025-10-08" version="1">MDALVAKYSKPAAIREDDLQLDEDMQLMELDAPVPGLSLKFAMPPVANPDAWLRAMTDDRANPQCPIKIAHGTTTLAFRFQGGIIAATDSRATAGNWIASQTVKKVIEINSMLLGTLAGGAADCQYWLAWLGMQCRLHELRHKRRISVAAASKILANLVYSYKGMGLSMGTMCAGVTKEEGPALYYVDSDGTRLAGNLFCVGSGQTFAYGVLDAEYSYDLTEEEALELGRRSILAAGHRDAYSGGYVNLYHIKETGWVKHGFSDMNPIFWQTKLEKGEFTNVTANLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKN5</accession>
    <name>A0ABR3ZKN5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">USP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000526</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021905">
        <property type="entry name" value="DUF3517"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF827">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12030">
        <property type="entry name" value="DUF3517"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="USP" evidence="1">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="757" mass="86641" checksum="3776CC4C8DDDC111" modified="2025-10-08" version="1">MPNNLIFHLKRFDFNLRTLQRSKINDHFSFPKTIDMNPYTVAHLSSPERSLEPDTFELVGVLVHSGTAESGHYYSYIKDRTSEPSTNKWFEFNDDLVTPWDPNQMESSTYGGLETRMPYENNSGPFEKSYSAYMLFYQRVSNLKEQQNHLAAKGLSLPAKVGVPVDISLSIRDENFLILRRHCLYDSGHVQFVAKMFNQTQAHHGTGPRPPHGEQKVGMGILLSHLDQVVSRVKGLPDFSEYESIINNAIYKCPECAMDFFQHFAYYKESFRVMLQRSPELCVRQDIGMMMLNALQILKKERPFAYHPRGSDCDDASACVLHSMLDILGHTWQAFHTCIRAWDEYFQFILSFAKMGDLETAHLLAEDYLVQFTQIVTVDQALQLTPQFSRLLNMMTRRAVSLKPVCLQYVFLIIEHFLNSLSPKFGQDHIVDDPRERLSWLAENGRPLPWSSTEVNAFHETFPYNTSNLFMAKICSYGQSPQLVERIIQRLTCAGPLMETHLMTTLQDGINGGFTHHRIAPYMRCAIWFCAESQNVERIVEMISFVSKQAINIQSMEGKIFPVFFKAIHQNALMRLQHDRTAGLGILNAVLDSTKIWAPWLLCYNQNSSPAETRVLTEDFLITALFHYGCPPKVPENEGGEEIAGMIRETVRQLGILCLQYINSNVIDTKTQVSRESMGAIQQTIARCSNYFDATSSEVEDCFFYNMGQNILDILQSFLVDQLEEEASDWDNSDVSSGQYVNIEEFATGDSIVMDRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKP3</accession>
    <name>A0ABR3ZKP3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">ATP synthase subunit d, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ATP7</name>
        <name evidence="13" type="ORF">Cpir12675_000597</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the ATPase d subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008689">
        <property type="entry name" value="ATP_synth_F0_dsu_mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036228">
        <property type="entry name" value="ATP_synth_F0_dsu_sf_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12700">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT D, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05873">
        <property type="entry name" value="Mt_ATP-synt_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005514">
        <property type="entry name" value="ATPase_F0_D_mt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161065">
        <property type="entry name" value="ATP synthase D chain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="5" id="KW-0138">CF(0)</keyword>
    <keyword evidence="6 12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR005514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1901231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="173" mass="19301" checksum="C839E3842F0C55E6" modified="2025-10-08" version="1">MATRSAATKLDWVKVASSLGLRGQTASSLQAFKKRNDEARRKLTALSEMPTTVDFSHYRSVLKNQAVVGEIEKRFASFKPATYDVTRQIKAIEAFEVEAINNAEATKTKVDLELKDLQKTLTNIETARPFEDLTVDDVVAAEPSIDEKTSQMVSKGRWVVPGYKERFGDLAVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKQ4</accession>
    <name>A0ABR3ZKQ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mitochondrial aldehyde dehydrogenase</fullName>
            <ecNumber evidence="7">1.2.1.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ALD2_1</name>
        <name evidence="7" type="ORF">Cpir12675_000514</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.5" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004030">
        <property type="term" value="F:aldehyde dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43720">
        <property type="entry name" value="2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43720:SF2">
        <property type="entry name" value="2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="6">
        <location>
            <begin position="6"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="472" mass="50718" checksum="08152BDDE37FEE3E" modified="2025-10-08" version="1">MGVKRDMIEVINPTNEKIICKVYAAGKEDVNAAVYAAKTAFKNPAWRALSGAERANLMRRLADLIDEHTETLAVIETVDSGKPLSASRSYDVPQLSEVLRYYAGWADKNHGQTIDVGPGKLAYTIKEPLGVCAQIMPWNYPLAIAGWKLGPALCCGNTVVLKIAEQTPLSMLYVARLIAQAGFPPGVVNIISGHGNVTGSALVRHKDVAKVSFTGSTAIGVEVMKAAAGTLKNVTLETGGKSPLIVFADAKIPQAVHWAHEGALSNQGQMCTATSRILVHERILQQFTKQFVEAVKKISVVGDPFANETFQGPQISKTQYMKILAHIKRAKDEGATVLTGGKAMAPLTSGKGFFIEPTVITNVRPNMHIYREEVFGPCVVIVPFSTDQEAIMMANDTAYGLGAAVFTQDIGKAHRVVRDIEAGMVWINSSNDSDVRVPFGGVKMSGIGRELGEAALQSYSQAKAIHVNLGEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLX7</accession>
    <name>A0ABR3ZLX7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ino eighty subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000396</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038014">
        <property type="entry name" value="Ies1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37287">
        <property type="entry name" value="INO EIGHTY SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37287:SF1">
        <property type="entry name" value="INO EIGHTY SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="575"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="583"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="619" mass="69895" checksum="F24F1B04EB06A5D0" modified="2025-10-08" version="1">MPDSPGASDASVASSPAPPTRTHTKTFTTHMYHDDDDSRLGERDTKSSRKSKGGQRDSTQSTVGKVKHLKKEDGDPLWRKDIQYDFLRAIFDDDNKVFLNSYEPERLGMQCFADLYIDTMARSSKTSKVLRDKLLSDREAAKGMAMVCLLVNMGRMNTTLNFFPEMRAQLRTYHAIPSLQAHQDTHAYKQLQDAPRLKSILKGAVEDRDEPRSILEIKAKNVPRTNPVNLIFLIVQSAQKIHELHFPLDQEFHDLVMKTNYSSITRAKAFLWLAWFYLESDFTEEGCDENPFGPGVDYGLNVANQGIPTLRTLTTEEENEENIDMPEEIEFGEEKRQLRHRILEHDLSAVAENNGKRAPRNTVSKLVDDGPAILPRIRPNKQDAELDSPRSTPPPRLLPNRVAGAGERGSSSRRTGQLKHHTLLEASSPGGSRGGDRERDVDTMPIRKSRPPTAHQLAVERNRNQRVEHILNRGLRKAHHRARKLRRQEGAFVRALRRMEYIDNALAPSDDEEGGPTAMFKQTGLGGLCPLKEEPDDFGEEFASYSASMRRINRRLERWSSARGRGISVVAPVKRIKNPADGNDMDADGNDPEENIGNEMAFDADVIMDETVADETVWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMG8</accession>
    <name>A0ABR3ZMG8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Annexin ANXC4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000828</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.10">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037104">
        <property type="entry name" value="Annexin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502">
        <property type="entry name" value="ANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502:SF107">
        <property type="entry name" value="ANNEXIN ANXC4 (AFU_ORTHOLOGUE AFUA_3G07020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47874">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="396"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="831" mass="94647" checksum="EDF9EA33F4D77E8F" modified="2025-10-08" version="1">MSSSLGGGISSSGNSRGSRSSVAHARTKLSLPLDDSDNDIAYMPTPSTMSHTRTRKPLDLDSDDESLSATMFNGSYMEDNMSAVSYHRSRHGSIDDRQRDREPERVRQKELGRQENSRSRNRPRDHHLDIDRNEREDNHGARGSTGGGFVAPYPEQYDIPTGGSCDYYDNKATPYPPQPQDNYHQELPAPQHNQGANYRQRASPAPEREKPRSSPHRHQASIANETGYQSDRHSRRRDREADAPLLPPRPDSRTAQSISRPRESSRHRDRSRRNSSDHRDISRSRHGSSSKSRPSTHASHLTYGEEDAIASSDDEEFDGHSGRKNYGHRLSVSHPEDEERRRRWSSGTGARPDIPKAHGALLAEDVDGHHRASRSHSRSLSVTHLVNRPLLTIDNSESSRRHARRHSSVSLAAPSPMLEPYRGTWQESSPMPSPILRNGPRQQLDSQIPEMSLNESPPEQPRRARFFHDATDYTVQIANAIKDARRPPDTATLIEVLPGLSSEQVAELSQEYRKMVTVGPQAKGVNVAKHIKMRLKDCEPNLAKACYLVTLGPWTGDAYWANFWYHGDKTRHELLIESLMGRTNAEIRKIKDSFRDKRYDNSLARCMKAELKEDKFKKAVLMVLDEGRMEDKDPDGRLVNIDVHQLNKDIRTLRKSILSPSGGETAMLKIILKRNDDYLKIILTEYERSYGSNFARDALKKCGNLVGEVIAHVLNGLINKPVRDAILLHHAITSSRDPVRNELLISRLVRFHWDSAHMEEIKRQFYFRYKTEISESLRAHIPGEFGRFCRELCISRMPNSIITIKRVSELQREHSEKEAAERDKTRLRQGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMR6</accession>
    <name>A0ABR3ZMR6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zinc transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">MSC2</name>
        <name evidence="13" type="ORF">Cpir12675_000627</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Functions as a zinc transporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endoplasmic reticulum membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000008">
        <property type="protein sequence ID" value="KAL1901138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045316">
        <property type="entry name" value="Msc2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45755">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45755:SF4">
        <property type="entry name" value="ZINC TRANSPORTER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="436"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="506"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="559"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="587"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="11">
        <location>
            <begin position="406"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase type 11" evidence="12">
        <location>
            <begin position="761"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="284"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="16"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="63"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="78"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="171"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="293"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="335"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="346"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU369017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1901138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1022" mass="112206" checksum="21BF30505043EFE9" modified="2025-10-08" version="1">MAHHESSGSPLMALISHPPFTHTHSPSHSSSHSQSNSRSFSSASASELVPASAPTPAVRSFSGGYTSTGTQKSSTTISGPSPSRSVSASLPHLQPGQHHYTNHVHTSPQHRHPQNLSQNSHPAYSDSNNSLQQPLLHYQRSRSRSPRPHSPLRYQQTSSSSSPDISTNNCHTKTASTSTSTHTRHLSLHHNYRTYSPGHNRGYGHASSSSASLPQYNSGYGYGLSSVNTASISTGTLSSRKMGAHSHSPSQLREVTPLTIDDFSSANTSQLSLFTSASGFDNMGAHGHKHRGHGPEKISGDFADDHGSGHDDTHKNEGGHGHSCSHDHKHDHGHDHHHHHKHGHDHGHNHGHDHDHDHDHDHVHFHAHAHSSMDDKSRITKFLLRYTSSYPFLNAIMVEKDSRRILYYMLLNVSFMMVQAFYGYVTDSLGLLSDTVHMFFDCMALLVGLVASVLGKRPPSQRFPYGLGKIETLSGFANGILLVLLSVEITFEAFERIWEGTETKRLGELLAVSVMGMVVNLVGMFAFGHHHHGHSHGGHDHSHGDGGCGGHNNENMQGIYLHVLADTLGSASVVVSTLLTYFTGHSFWDQLASVFISVLILGSSKPLIMSAARRLLLGIPDNIEYNLRNTLSGIAQQRGVLAYSVPKFWMDDRLGRENRLLGFVHVVAVKGASLEDVRDRVQNYLSQHNMDIVVQVEREGDASCWCDIGRAASGLALANASSLRPTFSSAKYVDARPHYPTSLVDRILKYHGSNNPRQSLIDIGCGPGNASLAFAGKFNKIVGVDPSEKMIEQASELSSKYPSMSFQVSLAEDLRAFPDAAFDMAIAGQSAHWFSNTAALSEIARAVRPGGSFALWGYNDNILVGYPEATAIFHDFLYRTDGEVAPGMESMAQYWEQPGRGILRTYFDQLVMPSEHWDEVTRKIYKPDFKTCQVAPGDAEQSGLWLEKRLTLGEFEAYVRTYSAFCAWRDANPKFVSKEDGGEGDIIDVMMDKMRASTEAFNVRGLEVVAVWGTALVMAKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNA2</accession>
    <name>A0ABR3ZNA2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 15">Amino-acid acetyltransferase, mitochondrial</fullName>
            <ecNumber evidence="5 15">2.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 15">Glutamate N-acetyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13 15">N-acetylglutamate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">ARG2</name>
        <name evidence="17" type="ORF">Cpir12675_000327</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 15">N-acetylglutamate synthase involved in arginine biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>L-glutamate + acetyl-CoA = N-acetyl-L-glutamate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24292"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 15">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 15">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the acetyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.1" evidence="5 15"/>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011190">
        <property type="entry name" value="GlcNAc_Synth_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006855">
        <property type="entry name" value="Vertebrate-like_GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23342:SF4">
        <property type="entry name" value="AMINO-ACID ACETYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23342">
        <property type="entry name" value="N-ACETYLGLUTAMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04768">
        <property type="entry name" value="NAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007892">
        <property type="entry name" value="NAGS_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51731">
        <property type="entry name" value="GNAT_NAGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 15 17" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7 15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 15" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="16">
        <location>
            <begin position="496"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00033251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR007892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1901637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="668" mass="73865" checksum="EE895C1DDBD31753" modified="2025-10-08" version="1">MLRRQAFSAASKLAGHHNESWPCQATLAQPHISRSYSGTAGVSPKSKVETEFDRDFFVSVLEASATKRDAKGYLQKYTSVENSLKLRLKIQPDQKMLQTKVASPTAVAPLERQINTLSTEIKQYAPTEPQLSASATEMPPLHLALMQIRFPQLMDEATKEGVAKSLSQLRTLGLLCIVVIDCGQSTTNKINREQCERLGYAINNYRGPGAKVVENTLAIDENLKASNISFSADGIFVAYPRELEQTLAKNVIPILPALASEPCTLRNVASAPDSILVSLVKYFTNLQTSATNDFLGRGPVENPMASSIEKIIILDQNGGLPFSRGSRFSHRFVNLNQEYDMILKDLEDALQSGSGAFNTDGYNENVSHIRSLKVVKDTLALLPTTSSALITTPMAAANVCPASSITQQYAADPPKSKLFGIAASVRTRKSLNPLIHNLLTDKPIYSSSLPFEKISGPSVVSPPDPKARMGTLVKRGSSVTIYPRPSVTGWVPPQPGAHRLRLTDNCIDLPKLSHLINDSFGRELDVAKYLKRMENNLAGVIIAGNYEGAAILTWERPSGLTEEMAYKESRFVPYLDKFAVLRSSQGTSGVADILFNSMVRDCFPQGVCWRSRRNNPVNKWYFERSRGTMKLPDTHWTMFWTTPKLFPGEMALKDYEDVCRNIQPTWLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP00</accession>
    <name>A0ABR3ZP00_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000084</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="193" mass="21129" checksum="47D2506B8ACC3B40" modified="2025-10-08" version="1">MTVSSQGLEYVKAFFCNPKESPESSPGANSRCRGRAQRWPGRPGGKPVFHPGDFAYEGGIDGRRGRRVPFARYREPRMGNGKDNGKGKYAGAGHPTAGSIDVNGGCLEGNSDENTKESSPVDAFCRISFDGGVVPSTTTKNQKKEEDQNALSLCVECNQSLPIQDADFKLFHTNVKYRERIEHGCVKLEIQDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPR1</accession>
    <name>A0ABR3ZPR1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosome biogenesis protein NSA2 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">HMT1_1</name>
        <name evidence="9" type="ORF">Cpir12675_000146</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the pre-66S ribosomal particle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
            <location evidence="1 7">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035242">
        <property type="term" value="F:protein-arginine omega-N asymmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11381">
        <property type="entry name" value="NSA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039411">
        <property type="entry name" value="NSA2_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022309">
        <property type="entry name" value="Ribosomal_Se8/biogenesis_NSA2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12642">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01201">
        <property type="entry name" value="Ribosomal_S8e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 7" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="67"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="260" mass="29448" checksum="61347770902350D2" modified="2025-10-08" version="1">MPQNEYMERWRKLHGRRLDHEERARKREARAGHKASKDAQNLRGLRAKLHAQARHKEKIQMNKKIRQHEERNVKTADEKDPSAPVPAYLLDRNNPGAAKALSSSIKNRRAEKAAKFAVPLPKVRGISEAEMFKVVKTGAKTKKKAWKRMITQPTFVGSEFTRRNPKFERFIRPMGLRYKKAHVTHPGLNVTVQMPIVSVKKNPNSPTYTQLGILTKGTIIEIDVSDLGMTTAGGKVVWSRYAQITNNPSTDGCVNSVLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPU3</accession>
    <name>A0ABR3ZPU3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Serine hydroxymethyltransferase</fullName>
            <ecNumber evidence="12">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">CBS2</name>
        <name evidence="14" type="ORF">Cpir12675_000177</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 12">Interconversion of serine and glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 12">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 12">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 12">Belongs to the SHMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="12"/>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049943">
        <property type="entry name" value="Ser_HO-MeTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000586">
        <property type="entry name" value="PRK00011.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680:SF57">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 12" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="9 12" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Serine hydroxymethyltransferase-like" evidence="13">
        <location>
            <begin position="58"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00006376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1902070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="530" mass="57602" checksum="1DF3EEF7629F5040" modified="2025-10-08" version="1">MRGVRGAVSLLARPVAPVLGVSRAAQLAGKAVGSGVLRTRGYVSSAFEGQQTLLAESLSQADPAVYEIIEKEKTRQKNFVNLIPSENFTSEAVLEALGSPMQNKYSEGYPGARYYGGNEFIDISERLCQQRALETFNLKPDDWGVNVQPLSGAPANLYVYGALLNTHDRLMGLDLPHGGHLSHGYQTPTKKISAVSKYFETFPYRLNEETGCIDYDQLEQNALLYRPKIIVAGASAYSRLIDYNRMREICDKVGAYLMADIAHISGMLAAGVLPGPFNVADIVTTTTHKSLRGPRGAMIFYRKGVRRENPKTKKPEFYDLEGPINSSVFPGHQGGPHNHTITALSVALKQAQSSEFRAYQSQVLANSRAFANRLGQSPEKGGLGYKLVSGGTDNHLVLADLKPNGIDGSRVERILELVGVASNKNTVPGDKSAMVPGGLRMGTPAMTTRGFTEADFTRVADIVHRAVGIAIRLNKEARKVATDKGEKLPGKLKLFMDYVGDGSEDPEIAVLRSEVASWVGTYPLPWAMAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPW7</accession>
    <name>A0ABR3ZPW7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL27B</name>
        <name evidence="5" type="ORF">Cpir12675_000040</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06090">
        <property type="entry name" value="KOW_RPL27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001141">
        <property type="entry name" value="Ribosomal_eL27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018262">
        <property type="entry name" value="Ribosomal_eL27_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041991">
        <property type="entry name" value="Ribosomal_eL27_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038655">
        <property type="entry name" value="Ribosomal_eL27_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10497">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01777">
        <property type="entry name" value="Ribosomal_L27e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01107">
        <property type="entry name" value="RIBOSOMAL_L27E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1902141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="135" mass="15653" checksum="A3EB653389EA4105" modified="2025-10-08" version="1">MKFLKVGRVAIITRGRYAGKKVVIVQPIDNGKKPHQFGHAIVAGIERSPSKITRRMSKTRQEKRNKIKPFIKVVNYNHLMPTRYTLELEGLKGAISAETFGEVSQREDAKKTVKKVFEERYTSGKNRWFFQSLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ02</accession>
    <name>A0ABR3ZQ02_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ACB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_000071</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000582">
        <property type="entry name" value="Acyl-CoA-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035984">
        <property type="entry name" value="Acyl-CoA-binding_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23310">
        <property type="entry name" value="ACYL-COA-BINDING PROTEIN, ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23310:SF133">
        <property type="entry name" value="COA BINDING PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12300)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00887">
        <property type="entry name" value="ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47027">
        <property type="entry name" value="Acyl-CoA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51228">
        <property type="entry name" value="ACB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="ACB" evidence="4">
        <location>
            <begin position="5"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="125"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="125"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1902171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="301" mass="34357" checksum="3F9C0DFFA267D70F" modified="2025-10-08" version="1">MADSMDRVFVHALSALKQMPKTGSTKPPVSDRLRLYGLYKQAMEGDVDGVMERPSRAVGITEDDLKREQAKWDSWNSHRSLSRTEAKRKYVEALVEILSRYATTPSGKELVSELEFVWDQVKNNTPSISDSSPYADSQHARQTRPAIRHGNTAMMEPTEPSPLKVLRPMSEVDEADLASEQQLAYEDGLDYGDDDGDDISVLSGHWARRVEKALVKLSTEIVALREQISTAQEWRARQGMTLRAWVKWAVWAVAKHIAMDVVVLCVVLLWMRRRQDRRLEDLVRGVLRLAREYVRKIVPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YCK2</accession>
    <name>A0ABR3YCK2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CDC15</name>
        <name evidence="7" type="ORF">Cpir12675_006898</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000410">
        <property type="protein sequence ID" value="KAL1886043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06627">
        <property type="entry name" value="STKc_Cdc7_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050629">
        <property type="entry name" value="STE20/SPS1-PAK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012:SF26">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE DDB_G0283821-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012">
        <property type="entry name" value="STERILE20-LIKE KINASE, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="55"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="338"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="489"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="589"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1276"/>
            <end position="1373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1414"/>
            <end position="1461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1529"/>
            <end position="1578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="30"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="506"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1290"/>
            <end position="1302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1430"/>
            <end position="1442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1452"/>
            <end position="1461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1530"/>
            <end position="1542"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1886043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1578" mass="173356" checksum="06B444CDA91EDE0C" modified="2025-10-08" version="1">MASSPPSTGTAIKVDRHYPLNSRMAAAASRPDRQGTPRREKMRETSAVQDPGLKDYARECLGKGAFGSVYKAFNWGTGEAVAVKQIKLGNLPKSELRMIESEIDLLKNLHHDNIVKYIGFVKSTDCLNIILEYCENGSLHSICKAYGKFPENLVGVYMTQVLQGLQYLHDQGVIHRDIKGANILTTKDGTVKLADFGVSTSTLASGQDKEAQVVGTPYWMAPEIIQLSGASPASDIWSVGCTVIELLQGRPPYHNLAAMPALFAIVNDDHPPLPEGISPAARDFLMQCFQKDPNLRVTARKLLRHAWIVGCRKSEPQVAKTPSNFSQAVEEVKQWNKALQSSDTPLRASIGSDGGLPGPTPPTRLKENGVAPVKGGPLSLVKPRQQLTEAFRSPELQDDDNWDDDFATAISPTALQLPRLKPQDNFGGLLSSDRLKAFASIDGASFDEDLDGDLLTIKGPPQQQMMPSFNDSFQDQTIRPVGHILAKYQEDSPEPDDPPKKENIRNRTRSSRPRSPIKHAKLELPQKPELAFREKQVDDYSDLFADDDDAAFNRGLHLAAKRGEHQGGAPQLFHPSDLAEFPKPIQTASVDGGLQRQPSKQPEFPDPPTRRPRLQIEIQRFAENDGEEDFSDIVGLEDSFHKDDASDRGSEIPDGRMILSKLSGGSWLGDEEEEDDPFASMDPGWDEMDLEANIARDRHARLCERVEQLVRSLQITETDDVLCDVTEELLIMTCENPEVKNLIISSHGLLPILEILEPCSVKSRQDMILLLLQVVNAIILDDVEIQENLCFVGGIPIISQFVARQYSDEIRLEAAAFVRQMYQTSTLTLQMFVSAGGLNVLVDFLDEDYDSTRDLVLIGVNGIWNVFDMQGPTPKNDFCRIFSRSKILYPLALVLHRVLDEEGEDQVSRLIEGRIVGIFYLFSQAENYVKEVVADRQVLKSVLKDLQRMSPQHQITMLKFIKNLSMLSTTLESLHSADAIEFLIDLLSYSIKRGHKHVREVSNQVLNTMFNLCRLSKERQEVAAVGGIIPLLLRIMKTDRPPKEFVLPILCDMAHSGQKARRYLWQNKGLDFYVSLLADQYWQVTALDAIHVWLQEETANVEGHLMHGDFSGAIISCFDTNRINSFDSNILEPLLKIVRLSPPLALTLAHPEMLFGIVQRLGHKKAVVRLNLLRLVRSIMDSYDPGYLGTGDGITSLNSSQVESLLESVKTHAEKDNAVLVRNLASDLVRSHVDSLVAYETASSSSQPGMNMGASIGISGSNGVIGINLNGTGAGRGPIRRAESAPRYNSPYTPTSVGSPSSSMPPTPNGGRRHRTSNAGLSRDPFADASASPRRKTVQDRESISYRPCSREGSIGTPRRVSGELPPSAMTGLSGLSGLAKRLPRAGSVYPRHGSVSNGTGTSGNGYSHVQAQAQAQAGYLQRAQSPMFQHSHSQSLSHAHSPTITNHQLNSSPSSPSLAAMSAASADRFAHVSHRRSESALRAFESANGLLPGGTSKENLVAGLVADRGGSRLRSSTAQSVAHAVENTQNMTQQQRQQQDLAHQHKSSRDGPNSSSGGGGGGILIKRRSRLSVSENW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YDE3</accession>
    <name>A0ABR3YDE3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000436">
        <property type="protein sequence ID" value="KAL1886010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1886010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="232" mass="26148" checksum="10397CB6D39A6FEC" modified="2025-10-08" version="1">MASITAVRPSHHNPRASDDFDTASIRSYVSEAPSYHTIPPNEKVPEYTARDVPPYTRTEPPRYGLPPIPTHRPVPLPSLAAFSIPTWSTVHSNPTSRNYQNIARRRMTAGSSSSINTTASTNSTAASTSTRTLDQEQPRAREPDAVTASSSSRPLEDPYLVGETAAAQARAQRLAREAQEDILVIEDRRWDWFLAHISDLESRERSWSRFRRNIENQQRGKRRRLARLGSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YDK1</accession>
    <name>A0ABR3YDK1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006906</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the avfA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000417">
        <property type="protein sequence ID" value="KAL1886035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020">
        <property type="entry name" value="FLAVIN REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020:SF50">
        <property type="entry name" value="UPF0659 PROTEIN YMR090W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="2">
        <location>
            <begin position="8"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1886035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="276" mass="29037" checksum="AFD78A54CF066608" modified="2025-10-08" version="1">MPTTLIFGGSGKVARHLTRLLVTPTGAVSGAPKAQHTVYSIIRDPAQSSALTDLGATPLVQSIESATVAELAATIQKVNPDFVVWSAGAGSGSSPERTQAVDRDGAIKLMDALAAARPAGSTNTAADDIAARRLIIVSAVDIRDRTNKPEPAWYTEADSTLSTRVWNAIGTYMEAKLGADRSLYTDNARRQLAYTIVRPGGLSDAPGTGKVRAGRVGLTGFIPREDVARAVVACIENPQTVGLAIDFLGEGEGAEPLEQAVEKVAKERVDCFEGFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YE16</accession>
    <name>A0ABR3YE16_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Tau 95 subunit of transcription factor TFIIIC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TFC1</name>
        <name evidence="8" type="ORF">Cpir12675_006882</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000403">
        <property type="protein sequence ID" value="KAL1886057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.160">
        <property type="entry name" value="TFIIIC, subcomplex tauA, subunit Sfc1, barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019136">
        <property type="entry name" value="TF_IIIC_su-5_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040454">
        <property type="entry name" value="TF_IIIC_Tfc1/Sfc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041499">
        <property type="entry name" value="Tfc1/Sfc1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042536">
        <property type="entry name" value="TFIIIC_tauA_Sfc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13230:SF5">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13230">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIIC, POLYPEPTIDE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09734">
        <property type="entry name" value="Tau95"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17682">
        <property type="entry name" value="Tau95_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="Transcription factor IIIC subunit Tfc1/Sfc1 triple barrel" evidence="7">
        <location>
            <begin position="55"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription factor IIIC subunit 5 HTH" evidence="6">
        <location>
            <begin position="238"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="122"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="543"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="601"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="9"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="558"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="622"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="656"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="692"/>
            <end position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF09734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1886057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="723" mass="82015" checksum="A1EFB27FBB4AD45A" modified="2025-10-08" version="1">MSSPAPPHSPHEDTPSIMDERESKGFSLPRFGTEYHSAPDRGAPSYTIQPRRFGAVEVPMVVLNIERARGAFGRTPSFPDILEPNRNSLQLYLNPDSPYIPPVLSHNASTHNVLLKVTVPKRTGRKRRRGADGPFEDAGQAVEDNLPETTGNNRSYGRLDHPKTLRRRLQDNAGSYHVEAVGMIRHTHRYRGLADFSWEASHSDFTKRFSQDILTGDINKIKNFKFTPGLDRSTNADIIPPPTFTHMTLPFNYNYEQNPYVRAVRDEGGEERVMNITAAVMVGHFVKPTVENVPTAPRMPPDLTDPVMADLMQDLDVAFAERPIWTRRSLLNRLGKKIKTWNVLKKYISYTAYQFKGGPFKDAVIAYGVDPRKDPKYRIYQTMFFKLPFVHSGTDKKTWHAIRKGQQLVYVEDSSTSHIFDGQTFYSNGKLWQVCDITDPMLAQMFADAAVRPTCDITGSGWFHQGLWAKAKAVMKCKLLAIRFNRQLDAGAFEMIHATRDETPPPGSYISIKLPSLNLTEDELKIMRGSRYKNNTRVVRNKQNITVKNKAEKAITMPDEDDEDDDEDEGEDEEEDNDDEGMTADNNSVYASRSYRNMSAQVHYGPGSGGQAMDIDTDVDMHQSSAYHSPQSYPYPYPPTNYAADHSRMGNRSDMQNEDDLYDTNDEEEYNDEDDDEDDEQDDDVGEGGSVDGERENARSNYKDFAMQIDPRLFHPRSPDTAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFC2</accession>
    <name>A0ABR3YFC2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Lysine permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">LYP1</name>
        <name evidence="10" type="ORF">Cpir12675_006784</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000375">
        <property type="protein sequence ID" value="KAL1886981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF4">
        <property type="entry name" value="ARGININE PERMEASE CAN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="334"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="392"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="422"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="467"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="496"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="9">
        <location>
            <begin position="65"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="9"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1886981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="557" mass="59487" checksum="365CEF5ED844C432" modified="2025-10-08" version="1">MFDEKSAAAGSSPNTTAMYDNKSATDSTSKSFADVDATPASPVSGSALATAETSGEMKRDLGSRHLQFIAIGGTIGTGLFLGTGNALATGGPIGCLIAFALVGVVVYSVMTALGEMAAYIPVTGSFAVYASRFVDPSLGFAMGWMYWFSWSVTFALELTAAGIIIQYWNDSLNIAIFITIFLVIFTALNFLPVKIYGDVEMYFSLIKVVTIVGWVIFAICVNCGVGKQDYLGFKYWKDPGPFVEVQAEGATGRFIGFWAVMVTASFSYQGAELVGIGAGETADPGKAVPRAVKWTFWGVFTLFVSTVFMVGLVVPSNNPGLNSDATDASASPLVIAANLAGIPVLPDILNAVLLTAVLSAANSNVYSGSRILVGLAEQGHAPNFLRRSNKSGVPMAGVLCTAGVGLLAYMNLSASGSSVFNWLLNIVAIAGLITWACISFSHLRFLQILKQRNIDRDTLPYKAPLQPWLSIFGAFFTVLITLTNGFQSFIEWSTEGFFTAYISVMIFIVLLVVHKLVYRTKMINIEDADISLPERDATGKLIKRDAQGNILIDVGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGE5</accession>
    <name>A0ABR3YGE5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">methylmalonate-semialdehyde dehydrogenase (CoA acylating)</fullName>
            <ecNumber evidence="2">1.2.1.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_006559</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.27" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000324">
        <property type="protein sequence ID" value="KAL1887394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010061">
        <property type="entry name" value="MeMal-semiAld_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01722">
        <property type="entry name" value="MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43866">
        <property type="entry name" value="MALONATE-SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43866:SF3">
        <property type="entry name" value="METHYLMALONATE-SEMIALDEHYDE DEHYDROGENASE [ACYLATING], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="6">
        <location>
            <begin position="87"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1887394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="545" mass="59370" checksum="BD30F01EE67419CA" modified="2025-10-08" version="1">MDPTSQPPPTPPASCLSEANRIDQFRVPHTPSDSGYPRKRSRYESMSSSSQSGLQATALESENTLAKGVTYNFVYNEFLISKSRCWNKVYDPASQAFITRVPESTLEEVQMVVNTAISAQVSWATLTPSRRRSRMLTLISILRQNSSKIRHALCIEVGKTLADVDAEFERGLDAIETACSVANELSGQHFPHHHAEIHTLNEPLGVCLAVTPFNFPFMIPLWSIPYALLAGNVMILKPSEKTPTVSQLLAECFLAAGFPPGVLSVIHGGPFVVDNLLSQPAVRAVSFVGSDIAGERIYEHAKATRKRIQAECSGKNHGVVLDDANKMKTLYAIAGSAFGAAGQRCMALSVAVLVGSTADWINDLVGISQRLVLGCGLDPTVEVGPLINQAAKQRVEEIITNAEAEGATVLLDGRNYHVPDYPNGNFLGPTILTNVKPYMSCYQEEIFGPVLACITMDTLEEAIQLINENRYGNGCTLFTSSPVTAQIFQRQVNVGQIGINVPILAPSGPVLRSGNKDSFLGDMNVHGRSYWQFYTQTKTVTSLWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHC6</accession>
    <name>A0ABR3YHC6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Calcipressin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RCAN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000347">
        <property type="protein sequence ID" value="KAL1887156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006931">
        <property type="entry name" value="Calcipressin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10300">
        <property type="entry name" value="CALCIPRESSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10300:SF14">
        <property type="entry name" value="PROTEIN SARAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04847">
        <property type="entry name" value="Calcipressin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="270" mass="29784" checksum="DE4EFD1D6361C279" modified="2025-10-08" version="1">MISASTSSSLAGSKLSSRRGSSNLSIDISCIPTMAQPTPITNTLLITNLDDPAIFNPQNLMHIRSLIEKSAQINTWSPLRSFRRIVVSFKTTENAQKVRHLWDGESILGHRTRVFFGQETPVGQPRDEHLTLPDAGKLFFISPPPSPPMGWEMRLEDAPNKQVHADDLADALAKLNQSAPGPSDALLDSPISPVDISMENNAQNEAGVPRMRSRSSTLIWHPEQHGHSSDKMLPCIAVEDTTGEQDLDDFFKTKPILAHTMRPPVELINN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHC8</accession>
    <name>A0ABR3YHC8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_006457</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000303">
        <property type="protein sequence ID" value="KAL1887686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03357">
        <property type="entry name" value="LbH_MAT_GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051159">
        <property type="entry name" value="Hexapeptide_acetyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024688">
        <property type="entry name" value="Mac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23416">
        <property type="entry name" value="SIALIC ACID SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23416:SF76">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12464">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01266">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="227"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="365"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="19"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="155"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="195"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="405"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="449"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="664" mass="72099" checksum="AF6DDF4F2BB7785F" modified="2025-10-08" version="1">MSSFTTLNKLATGVMNKPAFDELRRVTQETSRETPPRDVLQTSPRTSSQPQIADRRPEPWDAAVESAKKSTSYPNVVEVNRKPTSYPDGVGICNKRKRSDSPDGRTKVPSQPNHREQKLHALSSPESNARMLPALGRDVYSTPRTDYEAGDSLPRTQSSRDSQSTQAIAEEVDTLRRVSATGEQSSDGVEPPPYSFSTDETGNKLTSNEEGGKKGRRRNFSHRTKTGCLTCRRRKKKCDEKKPECANCTKGGFHCAGYQQQNGPLWSEVEAKNPVALEPKEFTYISPPAAAGYNDGISYNSSISDVKRDQGQHYRGQALRIDPPQNRSILNDDKCLTPTVTGASVASPDNKLAAIHSFSANAFPTPISANPGPPLSNFSDRMNKDYSRVPPLHDIGRTSAPETAHSGNGASLPQINILNPTRSNSPGMAAPASQVAQMALSHGSFSHGSPQLQHQSHKPQQQLPPQRTEKEEMRAGRSYYYRDRELIEDRERCSTACWRFNNLALPHNGISSQERTRLFHEILHPSGSSPNRLGNISVIEGPFTCDYGYNVAIGQNVLISRDCTLQDAGSISIGDNCHIGPNVKMYTGTVSTDPKRRGGASGTQMAKPIIIESDCFIGGGVVILPGVTVGKGSTVGAGSVVTRNVPPMTVAVGNPARVLRGVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIM5</accession>
    <name>A0ABR3YIM5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Autophagy-related protein 101</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_006269</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG101 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000274">
        <property type="protein sequence ID" value="KAL1888175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012445">
        <property type="entry name" value="ATG101"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13292">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13292:SF0">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07855">
        <property type="entry name" value="ATG101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0072">Autophagy</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="85"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="90"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1888175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="225" mass="25515" checksum="1F3FF155C6074DC5" modified="2025-10-08" version="1">MDQPQQQNPHEFVLEAISDPDSVREIVKALLHTIFFHRYFPTIEPRTRRCLDLPLPYVVDAELETLIDQRVAKLAHDLELARVGPGGIRTGTPSANSSTTSSPLPLPHGGVSQADQSGNKRGIVKIQFFERRRRTGWIPRADEEVCWESWILKVSLAQPRNDNDRAKLRKAMSRTLLNEVINITNFVSLNKGHIPPITSSSNNPFPYQITVNPKEASWSGRLRMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIQ3</accession>
    <name>A0ABR3YIQ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">F-box/LRR-repeat protein 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_006602</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000332">
        <property type="protein sequence ID" value="KAL1887299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050866">
        <property type="entry name" value="CNG_cation_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057207">
        <property type="entry name" value="FBXL15_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45638:SF24">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_2G03170)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45638">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16643">
        <property type="entry name" value="cNMPbd_u2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25372">
        <property type="entry name" value="DUF7885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="10">
        <location>
            <begin position="69"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="10">
        <location>
            <begin position="260"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="F-box" evidence="11">
        <location>
            <begin position="554"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="194"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="455"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="706"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="944"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="527"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="729"/>
            <end position="743"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1887299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1002" mass="110756" checksum="5A15397B3E505582" modified="2025-10-08" version="1">MRRSRTSQSSAFRALASMNNGTSQDPAALIRSFNVETNPTRPVYPSPLTASTIQDMPLDLLDRVRSFPLFNSAPEEFLVAVGQHLKPQIHTPSDHIIREGDEAKAMYWIVRGVVAVTSRDGEAVYAELKPGSFFGEISIIMNIPRTATIVARTKCLLLSLKKEDFQVELPKFPEMEKLIRDEAQERLTILKKKRQDRLLTQHQTRHSQSGALSRDAQQTSPPNPKKRKSPSPSLIEGPSVGSALGSAQVNIRTTLKELPLFSTLPADVLHFLGLSAQPKTYPPFTDIVLQGTPGNEIYFIVRGEAEVIHDTWAADARPNVRNEVDTNNSTDKGLLKAPYIAMAQRPRLRQGQYFGEVASLGLAHKRTATVKAITTVECLMIPGPALEELWRNSPPDIREQVEETAKERFNNSSDGDVGMTEVPAIDTESAKSSLGHREKCNQSVTDQFASFMFSGSAKPMTQTPDEKSRPTPDPDPFLSVDMENLRNRRKGSIAPPTPPADSSSPALSHVKPVHPLSMDPMSITAPPVAPLHSPPPDLDEAPAKRARIQPLRRESAKQPVPDPVLEMVFATLNISEIMRLRRVCAHWKRILTTSPKVCLRVDLSLFNRVITDQLIKDVLAPFIGQRPEYIDISNCFHMTDDGFNSLWKSCGRNVKCWKMRSVWDVSANQILEMSEHSKMMEEIDWSNCRKIGDNLLARVTGWVVPEIPPGPPGPLQRSATTGSKGKMSPQKQRQAPQQQQPVQRATTMSIPGTVVGCPKLKKLNLSYCKHITDRSMAHLALHASSRLESLTLTRCTTISDAGFHSWASFRFTNLSHLCLADCTYLSDNAIAALVNAAKNLTHLDLSFCCALSDTSTEVVALGLPRLKELRLAFCGSAVSDGSLGCVALHLNELEGISVRGCVRVTGGGVESLLEGCSKLKWLDVSQCRNLEPWVRSGEISRYGHDERGGNGIPEGQEIITPPPVPEPSGPRLFVNRSRALVPRRRDREKVKFILQKSGFGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKA0</accession>
    <name>A0ABR3YKA0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Protein transport protein Sec61 subunit gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_006392</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SecE/SEC61-gamma family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000293">
        <property type="protein sequence ID" value="KAL1887854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.820">
        <property type="entry name" value="Preprotein translocase SecE subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00422">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023391">
        <property type="entry name" value="Prot_translocase_SecE_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008158">
        <property type="entry name" value="Translocase_Sec61-g"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001901">
        <property type="entry name" value="Translocase_SecE/Sec61-g"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00327">
        <property type="entry name" value="secE_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12309">
        <property type="entry name" value="SEC61 GAMMA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00584">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103456">
        <property type="entry name" value="Preprotein translocase SecE subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01067">
        <property type="entry name" value="SECE_SEC61G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1887854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="70" mass="7650" checksum="01078635BD47F6C7" modified="2025-10-08" version="1">MSDAVQEFVEVPAEFARDGIQFMRRCTKPDQKEFLKLCQAVGVGFLVMGAVGFLVKLIHIPVNNILVGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKV9</accession>
    <name>A0ABR3YKV9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_005969</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000236">
        <property type="protein sequence ID" value="KAL1888981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF131">
        <property type="entry name" value="TYROSINASE COPPER-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046813477" description="Tyrosinase copper-binding domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="3">
        <location>
            <begin position="296"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="587" mass="65403" checksum="729DBD47BD4D040D" modified="2025-10-08" version="1">MLSSSLLAAVASFAAIADAALIPVTGRTTGIDPSTNAVPMRRNINDLYNENGPEFQLYVQAMSVLQTKDPRDPESWFQIMAIHGAPTMSWNDEPQSTTGIDEYCPHSEEIFATWHRPYTILYEQALGKAASDIAATYPVSMRDEYQKAADRLRSPYWDWAEDYNVPPVSTIENLTVLRPNTNGSALVNTTIPNPIYSYRYPTEAMNGEFANFVPSSDHTRRCPDANGISQPAQANQGLAERGLKEAVYNTFTRSNTFLSAMSQRGRGASFESPHGVVHVYAACGEQLINMRESAFDPLFMLHHTQVDRLIAMWQAMYPSEDMFTYSYPTYGTYTIPADVEINSDTELGPFRKSDGSMHSSMSVRNIWDFGYSYEGIEPWSRSAEIMTRDIASIVNTKYGPQGTPVASSKSRRNAQRRSATVEYFAEVRLTVDKFPRPCSMLIFLNDKPAGTFTMLEHPMKGEVNGEISLQKGIEAAGITGYTEEDMLAAIQKAMVIKFEMPDGTAVAVDQIDTYTIEIEQVSVLKPSQPEELPSYGLSKLFETIPKLINVDLDIDLDESPSFKLNINGLGVSINIDTSDDDEENKEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLN2</accession>
    <name>A0ABR3YLN2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">G2/mitotic-specific cyclin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CLB2</name>
        <name evidence="8" type="ORF">Cpir12675_005952</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000234">
        <property type="protein sequence ID" value="KAL1889034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20512">
        <property type="entry name" value="CYCLIN_CLBs_yeast_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046965">
        <property type="entry name" value="Cyclin_A/B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02984">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001771">
        <property type="entry name" value="Cyclin_A_B_D_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01332">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 4" id="KW-0195">Cyclin</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="6">
        <location>
            <begin position="238"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin C-terminal" evidence="7">
        <location>
            <begin position="331"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="6">
        <location>
            <begin position="335"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="129"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="467" mass="51986" checksum="BFCCB9725588B9BB" modified="2025-10-08" version="1">MPPSEMTTRRMLSNENDNSAAVNAIVRAKASALNAEPAAKGLQTKKVANGSGIPRKRAALGDVSNMGKGDVVEGKKKGLVSKATSQVTSRVSTRSAVARANGITKEKKQTIELKRAASTSGVQKRKALASAASEAQADGQPSRKRISVESDKGTKAAVAVPHVPMAPIIENITEKKTIYPSGVRNLEDDDFDDPLMVAEYANDIFEYLRQIEPDTLPHPDYMDVQDDLEWKTRAILVDWLVEVHTRFHLLPETLFLAINIADRFMSQKTVHLERLQLVGMTAMFIAAKYEEIISPSVTSFRELAEGGFSEEEILSAERAILATLDYNMSYPNPMNFLRRISKADNYDIEARTIGKYLMEISILDHRLIGYPGSLLAAGAMYLARLILDRGEWDETLAFYAGYSEEEIEPIVATMVDYMVRPTTHEAFFRKYACKKFLKASIISRNWAKANMRHFRISNPMVSVDDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLW5</accession>
    <name>A0ABR3YLW5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Nucleolar GTP-binding protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">NOG2</name>
        <name evidence="11" type="ORF">Cpir12675_005857</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Nucleus</location>
            <location evidence="2 7">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000223">
        <property type="protein sequence ID" value="KAL1889291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01858">
        <property type="entry name" value="NGP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024929">
        <property type="entry name" value="GNL2_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012971">
        <property type="entry name" value="NOG2_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050755">
        <property type="entry name" value="TRAFAC_YlqF/YawG_RiboMat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089">
        <property type="entry name" value="GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089:SF9">
        <property type="entry name" value="NUCLEOLAR GTP-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08153">
        <property type="entry name" value="NGP1NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleolar GTP-binding protein 2 N-terminal" evidence="10">
        <location>
            <begin position="43"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="G" evidence="9">
        <location>
            <begin position="376"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="548"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="548"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="578"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="610"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="624"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1889291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="633" mass="71459" checksum="51728A67FCD0C6A7" modified="2025-10-08" version="1">MGNRKKESSRRVREGKSTDGMANVRVKGENFYRDSKRVKQLNMYKEGKSQHNAKGEVVVAAAFQSREVPKALIEPNRKWFSNTRVISQEALQAFRAAMTERADDPYSVLLRRNTLPMTLIRDGDGVNGLKQHKAKMTVESTPFSNVFGPKAQRKRVTINSSTLDDFVDEAEKTLDSYEEQLEQDRLLSGNPNDPEDDSVKIAREHVFSKGQSKRIWNELYKVLDSSDVIIHVLDARDPEGTRCKSVEKYLKNEAKHKHLVFLLNKTDLIPTTVAFCQDLIRIFMLQPLLVQWKGSVTLWANQIYTSTAPQRFAGRASMLRFGVCPEDAAWVRRLSKDAPTLAFHASITNSFGKGSLISLLRQFSTLHSKDRKEIAVGMIGYPNVGKSSIINTLRAKKTCVTAPIPGSTKIWQYVSLMKRISMIDCPGIVPPSMTDTPEDILLRGVVRVENVENPEQYLPALLAKCKRHHIERTYELSGWNTHIELLELIARKSGRLLKGGEPDLDGVARIVIQDFLRGRIPWFTPCPKGEDVEDATFKACDGRLGEMSRKRKRDFNETNKEGSVNEESVEDELKSFSEEEEEESVSVSYEDEGASRNDIPSEKIPAADATSDKVEEGPRRKSPRTSSRQSAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMF1</accession>
    <name>A0ABR3YMF1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005753</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000213">
        <property type="protein sequence ID" value="KAL1889536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="173"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="227"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="387" mass="40773" checksum="551C264B7FC02560" modified="2025-10-08" version="1">MTTSRSSRRRSQAAAAAAASHINASLHTSPSNLQPITRRSTIATSTSTSASVATASAVASTSPAAAAAAPSSASSSSLPSHHSHEPEQEMSSAIKGGHSLRRRKTVDYGENAASAAPHGAASSSSLGHLDSTGRDIGYRTRTQTGAVAKTRKRIVDDDSGEDDVPAAKRRNGTSSSSSTSATAPTPSAAPPSLTPRKNPTRASRRPPKSSRFVDSDSEDNQAQQDTPASSRPSRLRAAANGKGTKKTMARSSSSSTAHSHPSDAEQSHDESSAPSDDACQDGGPDDLDSDTDLSESIMPHRRSTVGPKLPSNERRFPSILPLNLSTGSLLGLPKEQAKMYRDASEYHQRVPELDVVRALPDGQQEVYRTRNYRLKQGERVYQAVSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMS2</accession>
    <name>A0ABR3YMS2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Amidohydrolase 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005728</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000211">
        <property type="protein sequence ID" value="KAL1889606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642:SF20">
        <property type="entry name" value="AMIDOHYDROLASE 3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642">
        <property type="entry name" value="IMIDAZOLONEPROPIONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="204" mass="21729" checksum="90767F2421102061" modified="2025-10-08" version="1">MHLLTTGQSMTKLSLVKCQNLEDIVATLKAYAAAHPEVPRILAGHWMHHMTGDRATAAALADVDPPKVASLSAALDAYCAAGYTGMIEMAMDEGGWEAALELRRQRGGVLPPNAEANKGGNAGRNRPRSRSPRPLASLAHAVTAATAGTAYSVFDENETGALKKDLRADIVVVDMQWEAHQLLQAKVLKTYSGGVLTFDAEAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPI1</accession>
    <name>A0ABR3YPI1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TATA-binding protein interacting (TIP20) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_005466</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CAND family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000188">
        <property type="protein sequence ID" value="KAL1890273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039852">
        <property type="entry name" value="CAND1/CAND2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013932">
        <property type="entry name" value="TATA-bd_TIP120"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12696">
        <property type="entry name" value="TIP120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08623">
        <property type="entry name" value="TIP120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25782">
        <property type="entry name" value="TPR_CAND1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="TATA-binding protein interacting (TIP20)" evidence="5">
        <location>
            <begin position="1130"/>
            <end position="1297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="360"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="470"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="361"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1890273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1316" mass="144320" checksum="B454820FE7E76456" modified="2025-10-08" version="1">MTGPPPTAASVSHLLPRLNDNDPDFRFMALTDLMQVLSVAKEDILHHDVHTASKAIEAVVSCLNDSNGEVQNLAVKCIGPLTTRIPLSLYGTLINAIIMLKLQHNVDNSLTSLAIRNSIMAFPRPSASITDNVGMSSIMVITSRFLVSRLISPELRPESDYITNPYRIDLLENVNEVPEKLDVLIELVRGLGAWLTKVEIELLLATLISCLSNPTSTSAVRKRAVVAISLITVYISDSALQNLVVQITQPLKDQKASPLIRRLYISIAGSMARSDPQRVGAFTSTLTPQIFQALGQEELDAHMELLANGDNGSVEFEDIRESALLALDNFLASCPQDMKPYTDQVVAAGLRFISFDPNYAADDDDEDMEDSDQDEDEDNDFDDDDFGDDDDTSWKVRRGAVKVLHTLIETRGGGDLLETGTLYSHIGPALIRRFGDRDESVRLEVISTLSMLIRKTEEIIFPTGQLESTEIESGAAPTASRKRRRQSSNLETPISPVVSLEPAGGIRIDLAHLSPGIVKESLKVLKGKLIPANQAVIKVLNSLVKARRGDIDDSFVPAVVAALNCLNTSGNNMTASTAAASGTASATPTTLKVTALVLIRDICRFKPSVLETQIEKIVSTLVSLIGEKFSKISSEAILTAKELVRSFIDTRSSLASSNFELTGMFDAIYSRVDPTSNKIDTEVRQYSIEALGVLISRTLVPQFSNLLSDHRRHSALQAIQARLSIETTKLTSIQTIEEIASFKAGSAQLEKSWVQAVMLELAKDINKSKRIVRSASIKALKHLAAAAIGRMEPEIVRQVVTLLIPVVDSDDAYMVTSALWVWASFVQQEPKLMTTDEVSKAIVTMLNTRSASIALEPLLVLVSHIGKSGCGETLMHQLLVSANNITDSTVYGRVIGSLLVAGGDSTGVSLDSFISELKPNPENDNRTALALTVLGEAGRQLGEKSPLDPNIFFVQFRPSFDRVSLAAAFALGRAGSGDVDKYLPLILEKLNAASDMQYLLILSLKEMLQNMSPDLMPHLKPIWSQLLTVANANLENRVVIAECLGRLVVLDSAFFMPKLQELLEHRTPMVRGLAIQAARYTLPESDEAFDTGLKSSLVSMLLVMLKESDMDNRRLGMMTLTSAVQNKPSIVLPRMGDLVPLIIDESKIKPELVREIMMGPFKHKVDDGLEVRKSAYETLYALLDTAFKSFSLSTFYDRVLAGLSDDHDIRSLCNLMIIKLASIVPKETTRRLDSIATTYQQVLSVKLKEGAVKQEIEKQGEAIKGVIHVTMVLVEKLHLAQSETGGETWSEYWRWVNREFSAQVKAIKKAQTEANP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQE3</accession>
    <name>A0ABR3YQE3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nitronate monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_005712</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000210">
        <property type="protein sequence ID" value="KAL1889609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332:SF28">
        <property type="entry name" value="DIOXYGENASE FAMILY OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G09600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="331" mass="35635" checksum="3AA7A774F4C872E5" modified="2025-10-08" version="1">MPLTTELTRRLGIEVPVVQGGMQHVGTADLAAAVSNAGALGIITALIFPTPAALTAEIERCRTLTTRPFAVNITLLPSLVPPDYAAYAQAVIDSGVRIVETAGNSPGPVITQLKKAGIIVLHKCTTVRHALSAVKLGVDFLSIDGFECAGHVGESDITNFILLSRARQELKIPFIASGGFADGMGLAAALCLGACGVNMGTRFLCTEEAPVHRNIKERIVSAQETDTALVMRRWRNTTRLFKNKITEEALKVERESKEGKFEEIAPFVSGKRGKEVFIRGDPEYGVWTAGQVIGLIHDIPTCKDLVARIEKEAEQTLKEKLSIIVPKASKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQF5</accession>
    <name>A0ABR3YQF5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000179">
        <property type="protein sequence ID" value="KAL1890586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1047" mass="118980" checksum="0284C25AEDFF983D" modified="2025-10-08" version="1">MVGRFSTPQLRSHASSSSPALDGDNDHTSRPVAGRSLPHLDSNAANAIDPLLVEDKDIWELIQGALRAPESPFSLTELENPPQSSCIDRNQSPEKSEFDYEKSWSLDDGLRLLDRAFEPEISKDPLTAEEKHILEPTPTALKEKAHKLRCIFNPNNPGEIPGGRSALAPQDALEYMKRFRRHFDLPESNTVTQLIATSPVLHYEQATAVEMLRSLFIEPRFPAPYEYKTLQKSLDRHGYTLENIKEWAWILSGDTEDECVTRLFDTGRGHPFFVLNSLLQTSNGSFVQRQSLSGLIKAVERSFVRDPPIANTRNAERYIANAAILMKYICAHCCRIWPSLLPICATMFVEMMEKTLPSIISNPEKLFVAQSALLNSSLQSFAKLSDTRAYKNSVFNWQSLRILLAYSDRQPKSFMLDRKSYVAVRLVLLASEHTPRERDIAGRLQDLWPPYPVPRDGIDEQVAPEENYSRVVKLGMMATEAGFNKTDLDREIDTLGGLGPDMTPTARQRAVLGNTNFSRTAREENIWAAKIRSTRNATEAWAVFNDPPTRRLTRPTARIYYALFRKLVARENTAPKYLPGDGRELTPIVIPNLTPFERARLTPPSVEQLYEQMKRDGTDADEACLSLLVQEAASVADACRYLEESTLTDEQYEAVAGPMLVENIETLRAVPRLIVSGFIRVLCRKHVRNQVDVELYHRATFYRIQKAVWLAWARFPGRHPSGVSVWRDICTVMSRSPTPRLHPNISEEANMAKLVPLFFRGFFHLLDSYGRDLESAANLFSIIEAYMVPHINAHKNFSLEKPLTGVMSVFAMEQQPPTQSNIPSAREYSRLKLTLLEQRQDSSSAEMAWLLRRFSGCFFNRIRDPGPLSPSSHDKVAASRDADDHSIDGEILPSIYTVPSDAVHRLMRAWAFTGNFAGMARLVRWIATEWTEGDLVDHEGASTRERNSIHNALCAFRLFAEPFRPVKEVNAMRDLIDNRAEKEDCGFSWPSEVERDLYGQGDLLGHAQLLKNVLDRILKQRGIVRKVHDLPDWELDMEEWWEKPDYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR57</accession>
    <name>A0ABR3YR57_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">2-oxoglutarate dehydrogenase, mitochondrial</fullName>
            <ecNumber evidence="3">1.2.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">2-oxoglutarate dehydrogenase complex component E1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">KGD1</name>
        <name evidence="10" type="ORF">Cpir12675_005349</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alpha-ketoglutarate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.2" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000180">
        <property type="protein sequence ID" value="KAL1890567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004591">
        <property type="term" value="F:oxoglutarate dehydrogenase (succinyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02016">
        <property type="entry name" value="TPP_E1_OGDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11610">
        <property type="entry name" value="Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1150">
        <property type="entry name" value="TPP helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032106">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011603">
        <property type="entry name" value="2oxoglutarate_DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042179">
        <property type="entry name" value="KGD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031717">
        <property type="entry name" value="ODO-1/KGD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00239">
        <property type="entry name" value="2oxo_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006914">
        <property type="entry name" value="PRK09404.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008907">
        <property type="entry name" value="PRK12270.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152:SF4">
        <property type="entry name" value="2-OXOADIPATE DEHYDROGENASE COMPLEX COMPONENT E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152">
        <property type="entry name" value="2-OXOGLUTARATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16078">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16870">
        <property type="entry name" value="OxoGdeHyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000157">
        <property type="entry name" value="Oxoglu_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="9">
        <location>
            <begin position="658"/>
            <end position="868"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00042984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1035" mass="117030" checksum="2C408D4D583295CC" modified="2025-10-08" version="1">MLSSSVLRASKGLMRSSQPVLRAFSTRRAPLAIANNLHQRLYSTVKSSPPDPNDSFLTSNAISYIDEMYIQWKKDPSSVHASWQAYFKNMETGDMPMSQAFQAPPTLLPNAGGDISNLTSSMDIKDKVTEDHLKVQLLVRAYQARGHHKAKIDPLGIRNTDQAKGFSNIDPPELRLSFYQFSEKDLDTEFNLGPGILPRFKEAGREKMTLREIIAHCERIYCGTSSSEFIHIPDREKCDWLRERLEVPQPFTYSVDEKRRILDRLIWGSSFESFLSTKYPNDKRFGLEGGETLIPGMKALIDRSVDHGVKDIVIGMAHRGRLNVLSNVVRKPNESIFSEFAGTANASDEGSGDVKYHLGMNFERPTPSGKRVHLSLVANPSHLEAEDPVVMGKTRAIQHYNNDEETHDTAMSILLHGDAALAAQGIVYECLSFHSLPKYSVGGTIHIVVNNQIGFTTDPRFARSTPYCTDIAKAIDAPVFHVNADDVEAVNFISQLAADYRAKFRSDVVIDLVCYRKHGHNETDQPAFTQPLMYKRIQAKDPQIDIYVKKLLDENTFTKEDIDEHKKWVWDTLEESFQKSKDYTPTSKEWTTSAWNGFKSPKELATEILPHSPTGVQRELLESIATKIGSVPEGFTMHKNLKRIVTNRTKSVLEGTNIDWPTAEALAFGTLVAEGHHVRVSGQDVERGTFSQRHAVFHDQATEDVYTPLQHISDDQAKFVVSNSSLSEFGVLGFEYGYSLSSPNAYVMWEAQFGDFANNAQCIIDQFIASGEAKWMQRTGLVMSLPHGYDGQGPEHSSGRLERFLQLCSEDPRFFPSEAKLSRQHQDCNVQIAMMTSPSNLFHIMRRQMNRQFRKPLVIFFSKSLLRHPLARSDIDEFLGDSQFQWIISDPEHKTGGLKPKEEIDRVILCSGQVYAALNKHRIDNKIDDVAITRIEQLHPFPWQQLKENLDSYPNAKTIVWAQEEPLNAGAWTFTQPRIETLLNETEHHNRKHVMYAGRNPSASVATGMKKMHIKEENDLLEAAFSVTQDKLKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRM0</accession>
    <name>A0ABR3YRM0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Prokaryotic-type class I peptide chain release factors domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005329</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000179">
        <property type="protein sequence ID" value="KAL1890577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052104">
        <property type="entry name" value="Mito_Release_Factor_mL62"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11075:SF54">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11075">
        <property type="entry name" value="PEPTIDE CHAIN RELEASE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="Release factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prokaryotic-type class I peptide chain release factors" evidence="2">
        <location>
            <begin position="57"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="159" mass="18258" checksum="818C8A0A8E832B56" modified="2025-10-08" version="1">MLRPLRTVVFNNHSAGFIQARYVRYKAFAVDFDPADLQEAREWARKVTHETLPRGNIVFARSSGPGGQHVNKTESKAITSWPIHEVITLVPRLLRPKLRESKYYTERTDSLSFSAQTSRQRSSNVDENRTKLLAELMCMYESTVPGESDLSKTHKYDKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS97</accession>
    <name>A0ABR3YS97_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_005053</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000159">
        <property type="protein sequence ID" value="KAL1891235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF19">
        <property type="entry name" value="MEMBRANE PROTEIN PTH11-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14080)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="260"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="36"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="554"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="570"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="599"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="626" mass="69059" checksum="0654226789DDFD46" modified="2025-10-08" version="1">MVFYTSPPPMSTFFEDKPTLLVCWWVTLFSTAIILIRVFGRLVRTEHLFFEDSISFWALVPIYLRMGCVHYVMLYGTNNADFSQTILTEAQLRHKQIASGLVLGARVFFAASLWVLKFSSLEFLKRLIDSTWKRSYTRTIRYARIALAVTFAAVFISIFAECQPFNHYWQVLPDPGGRCRQGYVQMLVTGLCNIFTDLMLVIIPIPIIVRSNMTVKRKAQLIVLFSLNLSVMIISVVRTHNVMLEHGEQQYRSMMASIELLFAVAASNSLVLGSFVRDRGVKKNKFRFDGDCAGLSPGLSDHQSIINSAAPGRHQVYKNHWGSDEDLVQGLGLGLKPELRQQDTITLDPKDQHPHFTPAPILLRPVISNTKKISDKWQMPFHQCSPSCAAEQSVDSPVPRDTNRRHPMYSHANSHNMAMLPRLNTQFASRPCFASSPMSPCPTQAAAIAKAASTPLTSTEQISFFDLGGLLAKGGSSGYNNADEEMNSSSFRRASYVPPIEPLTEAQLQNQSYWAYQSAMLAAPMPTVGLLSPNPGSGKRFTAARLYDLGGLLPPGSPDVISPDNEHSRPPSSEGSSVRTECGSIRAPAHSPPPPPPATITQTAATAPAPESPDVPSFVDVSGLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSV2</accession>
    <name>A0ABR3YSV2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pre-rRNA processing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RRP12</name>
        <name evidence="6" type="ORF">Cpir12675_005189</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000167">
        <property type="protein sequence ID" value="KAL1890923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012978">
        <property type="entry name" value="HEAT_RRP12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057860">
        <property type="entry name" value="HEAT_RRP12_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052087">
        <property type="entry name" value="RRP12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48287">
        <property type="entry name" value="ARM REPEAT SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48287:SF1">
        <property type="entry name" value="ARM REPEAT SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25772">
        <property type="entry name" value="HEAT_RRP12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08161">
        <property type="entry name" value="RRP12_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRP12 N-terminal HEAT" evidence="5">
        <location>
            <begin position="25"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="RRP12 HEAT" evidence="4">
        <location>
            <begin position="342"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="998"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1045"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1159"/>
            <end position="1293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1002"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1014"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1048"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1165"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="1209"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="1238"/>
            <end position="1268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1890923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1293" mass="140877" checksum="2511F060C636F479" modified="2025-10-08" version="1">MATPTLAEKLDKIKSPGLQSQQKNVIVLSAVESTIKEQNATPTPTAYLAALLALLNQSIANDNANPEITASVIYLLDVVTPYAPQSILLAKFTSVLTFVAPVLVLQDGEPSLLRSSIGCLESLLLAQDAAAWDLPATEISPRRAVAGLLHLSLDHRPKVRRRAQDALTHVLRNPPPSPSLDHPAADMCAHTAMKSLEDLVAKSAQLRKQSKKADAHDPTLIHALQLTKTVAHASGGWPSKAIEPLCELLLGIAKTGNEYMAMAVFDIFEVIFAGMTDQTMSAKLPRLMEIISELQPAGNDTQLVPPWVAILSRGYEVSAQLEPEETLQKLPEIFALVAHFLESSSENIRISASQCLVSFLATCVPKQTILDPSVFDQKILEKVASIAESLLSVRYQAAWMETFTVLAAMYDALRWTAYPIMMGITKNIGDIRMHGAFQNKAKADEVIGKAIRAMGPEAVLSVMPLNLAKPVKGQPGRAWMMPLLRDYVSNTNLAHFKSEFVPLSQVMYQRVMEHQGERTMEIKIFETLVQQTWSLLPGYCDLPLDLIDAFDQEFAELLANLLYSQPELRMDICRSLRMVVESNQAIAAIEDDEDEKDENEDLVLQSRVSCAQAKKNLEYLSAFVGNFLAVLFNVYTQTLPQSRGPILQTINAFLSITPETELIETFERVSQMLAVELNNSVPKDDKENKTPKKDALPSTSQTLMDLVITMSIYIPRASFSTLFEISSVAISRGTEPQLQKKAYKLIPRLAESATGQMALNERNAELQELLVSSASKVSAPARRERLAAISALLPFVPTSDLHFIPAILSEVVISCKENNERARETAYGLLVQMGQIMANANGALIQNSKVAHMPDDSPAVPATIEEYFTMVSAGLAGSTPHMISATITALSRILYEFKDAISVQTLADLVQTMDLFLTSNNREIVKSVLGFIKICIISLPLDLVTPRLQSLVPNIIVWSHEHKGHFKSKVRHILERMVRRFGYDAIYRNTPETDRKLVINIRKTKERSKKKKQAEKDANREGGSDSDEGADNHKFQDAYDQALYSSDSENDGEAASDDEGEGARSSRSRGANKKGGNAYIIEDDDEPLDLLDRRALANISSTKPVKLRKPTKNKAKTDLDGKLILGRDDDVSMDIDDDNNGTVAGGESGVGAYVAALKSKEAGRRVRGGKLKFSNKRTNSKDSDDEDDEPMAESTVAAAAGAFRAQQRGRGGPRGYGGRGGHGGHGGRGGHGDHGGRGGHGGHGGRGGYGGRGGRGGRGGRGGSGGFTNGRRSLGGERRRGGGGVMKSPRHNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSW2</accession>
    <name>A0ABR3YSW2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Tryptophan synthase</fullName>
            <ecNumber evidence="5 13">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">TRP3_2</name>
        <name evidence="15" type="ORF">Cpir12675_005118</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + L-tryptophan + H2O</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the TrpB family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the TrpA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="5 13"/>
    <dbReference type="EMBL" id="JAWDJO010000163">
        <property type="protein sequence ID" value="KAL1891110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06446">
        <property type="entry name" value="Trp-synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04724">
        <property type="entry name" value="Tryptophan_synthase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00131">
        <property type="entry name" value="Trp_synth_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00133">
        <property type="entry name" value="Trp_synth_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006653">
        <property type="entry name" value="Trp_synth_b_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006654">
        <property type="entry name" value="Trp_synth_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023026">
        <property type="entry name" value="Trp_synth_beta/beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018204">
        <property type="entry name" value="Trp_synthase_alpha_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002028">
        <property type="entry name" value="Trp_synthase_suA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00262">
        <property type="entry name" value="trpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00263">
        <property type="entry name" value="trpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48077:SF3">
        <property type="entry name" value="TRYPTOPHAN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48077">
        <property type="entry name" value="TRYPTOPHAN SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00290">
        <property type="entry name" value="Trp_syntA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00167">
        <property type="entry name" value="TRP_SYNTHASE_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00168">
        <property type="entry name" value="TRP_SYNTHASE_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 13" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="11 13 15" id="KW-0456">Lyase</keyword>
    <keyword evidence="9 13" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 13" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="14">
        <location>
            <begin position="354"/>
            <end position="673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1891110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="700" mass="75082" checksum="94D07F899E99F79B" modified="2025-10-08" version="1">MEAINETFRACKAQNRMALVSFVTAGFPTKESTADVLLAMERGGTDIIEVGAPFTDPIADGPTIQTSHTVSLKNGVSITNTIEMIKDARSRGLKAPVLLMGYYNPFLAYGEEKLIDDCKAAGINGFILVDLPPEEAITFRGLCSKVGLSYVPLIAPATSDARMQILCKLADSFIYVVSRQGVTGASNKLNSGLPDLLARVSKYSGGRPTAVGFGVSKREHFDMLAGLTEGVVVGSQIITTLQNNGPVEGPAAVEKFCAEICGRDEQDRKTAAADLTKATIKNTQAEDLALVGQLSNLHGSLPARFGEFGGQYVPEALMDCLTELEEGFGKMIDDPSFWEEYRSYYEYMGRPGHLHIAPRLTEHAGGARIWLKREDLNHTGSHKINNALGQILIAKRLGKTRIIAETGAGQHGVATATVCAKFGMACTVYMGAEDVRRQALNVFRMRLLGATVVPVTAGTQTLRDAVNEAMRCWVTDLKTTHYIIGSAIGPHPFPTIVRTFQSVIGNETKAQLQKEIGKLPDAVVACVGGGSNAVGMFYPFSKDLSVKFLGVEAAGDGVDTLRHSATLSTGSKGVLHGVRTYILQNDEGQITDTHSVSAGLDYPGVGPELSQWKDSGRASYISCTDAQAFSGFRTISQLEGIIPALESAHGIWGGIELAKTMDKDKDIVICVSGRGDKDVQSVADELPKIGPIIGWDLRFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT48</accession>
    <name>A0ABR3YT48_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SCP2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004922</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000152">
        <property type="protein sequence ID" value="KAL1891550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="entry name" value="SCP2 sterol-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003033">
        <property type="entry name" value="SCP2_sterol-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10094:SF25">
        <property type="entry name" value="SCP2 STEROL-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10094">
        <property type="entry name" value="STEROL CARRIER PROTEIN 2 SCP-2 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02036">
        <property type="entry name" value="SCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP2" evidence="1">
        <location>
            <begin position="17"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="128" mass="13581" checksum="D0A1E57B4EACC713" modified="2025-10-08" version="1">MGLKNDKFPSSAAFEAINAALQADETEKKTAIKQGNAVFAFVLKNAAGETESWHIDLKKTGAVGTGTGENPTVTLSLSDENFGKLVAGKANAQKLFMGGKLKIKGDVMKATKMEPILKKAQTKSKPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVK7</accession>
    <name>A0ABR3YVK7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pinin/SDK/MemA protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004557</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000132">
        <property type="protein sequence ID" value="KAL1892404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006786">
        <property type="entry name" value="Pinin_SDK_MemA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04696">
        <property type="entry name" value="Pinin_SDK_memA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pinin/SDK/MemA protein" evidence="2">
        <location>
            <begin position="2"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="297" mass="32648" checksum="E11A16F8C25A9E58" modified="2025-10-08" version="1">MRMQAQCLRTRAKPSLFYRPWKLTRDQEDDLDAQYDEMESKISRELASFRRRYDDAIEKYGTPVRRARASSTNSRRTDSSTSRSRGRGRNKSRDHSSSRNSNYVSHSRSRETDDIAMRDHTPSTERSDVRITTQHKEDVPAMGQRREDEAGPIGSENKAEAKSGPVGQSDSEQGNLTESGISSSGDPTGDGHHTTNPDNMQEDITTEGSAAETTPIELESKSKGGVVLDATAAVGKDETMPEQAATATSENQQGIEGEASAERSALAKMEQTTSVDSGRHDESGDVVLEADEDVLIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVN4</accession>
    <name>A0ABR3YVN4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004548</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000131">
        <property type="protein sequence ID" value="KAL1892434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021514">
        <property type="entry name" value="DUF3176"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37576">
        <property type="entry name" value="DEFECT AT LOW TEMPERATURE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37576:SF2">
        <property type="entry name" value="DEFECT AT LOW TEMPERATURE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11374">
        <property type="entry name" value="DUF3176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="505"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="611" mass="66223" checksum="A7372C76A7B849FC" modified="2025-10-08" version="1">MSSAPLYQRPSAGNETEVLHFDREVQPSRGSTTNIDRVALSDSMTTLNGSQNAGRTASPMSQLQEPVSISEVTRTPWRPGVFRAFPVWAILSIGISLCCTIVALCVVLNVNGQSVSKYGNSSLQPSVILAYTSTVANTALAFAMAEAGTVYYWTQALAGTQLVNLHYNWLACQGPLGGIKSLIKRRAIVPGLVCLAVGISTLLRGPLVQRVLDINSIIVPVSGSIEAPVGQTMLGYFGQRRSPIPAPSDNFTAVASQLQQRMPMAFANTTQPCTNCSMSAVDGFGFDIVCNQTLTPYNMTIYDSGKGTSNLTTLSVDFSTARLGNFSSVFMNVTRRPTIKPAGHLITDLCQLYLSRMSYKLNVNGRNVSFQAPSYRDDTVVERLQLESFDASYGSSGLSSYGKVTYGTTARSTFTFPYTTSDCTGPLCFTYHIGEKYVPLGQSNGNDPNWIIGDAFNSPTDDILNHFRELAFRLSLDYGTRMSIQQNLSYTSERSDVIYVINHMALVPAAIVSILGPLAILPLLLNWWDLGRETSMSPLELAVSFKTLTRNGIPLGDTSANIGGNSLAGLLNKGPAKDTHVQYGVAEDDILGMWEHGKESSLRRPIKGELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVS9</accession>
    <name>A0ABR3YVS9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Autophagy-related protein 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004666</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000137">
        <property type="protein sequence ID" value="KAL1892157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="353"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="134"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="191"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="366"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="537" mass="58545" checksum="FA57BA2AA20C2420" modified="2025-10-08" version="1">MDLPTLERISRDYGLGLGNSRLQAMLEDDLFASWAGLHLTPDNLLTADELAAYSALQASGTVDRLAASEDLSAPGLAVFSDFELRTAIQMLTASTAQLTQHTRALQAQKSSLARLSSVQSTRDASRSRLADAHLARRAAAMAEAEARLREAQDHVAEKVADSRMNVEQASSEAARLVCSIGEADDEVLQGMEKLARELVGGEEREAEKEQELDKLNNEAMRLIKSTVELARTRLDRVYLDGLTSPLAATGFGTDELESTEALQIEVESLYAEILPVAQMAVENSFLEPARSTLLAQHTAERQHTAAGLRYTNECFEHLLDRMRRVKHRLETLQAHQATTILLVEAAEKELSTPITMPALPQSPDNSTPTATGTSPAPTTGRPKTSDPATPGPARRRCNSSLASTAFERALHTLGVKPPDPMAATSKAMADLQLLQMLARTTAQRSLTVQETSRNAQASFESSAAHHLADSKRDIDTLLDHIKADYPFGDVGLADPSMAESLAWIGREVKEAQERIANVQTSRVMGGEEKDKFVEMWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWJ6</accession>
    <name>A0ABR3YWJ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004409</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000124">
        <property type="protein sequence ID" value="KAL1892711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="138"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="362"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="549" mass="58767" checksum="05F463D8D694D491" modified="2025-10-08" version="1">MAGLARASSSRFLEGSMNDRISAVPPVEFIGYKNSAPSSLGSQTDQDNDYDDIAAEFLTCSSPRTNSNSTIDAQLSKIATSNTKKSASTMGNKSKGEKRSSFLPSLWVGFREKLSFRKGETKRRPHSMHAGVLLGSRPTDLSSTSVTTSTPPPDISEPQAVRASNAFKPPLGMGMGNNGARPTREEVMANYKSLMAQGFFGNHAIQSTRQPPPKPLSTSQSMGNFAAIFNNSQLAPGTADGLRSNPVPPTPTSMEQDDESMAPAKFNPEAHPGAPAARPATPAASRPVSSPMDRDVGIMSGWLGGSGQRRGMKRSNAEALDKEVPTQKKLRKSASRMGDLGNLGKLRKRGGEISGFLSGRSFSAASSSSGSLGKLNGPTSPLVNDMPMSPHSPLHPNPFAQHPVHIPPHPAPTSTPAPLNRLKKRPTMTDISAPLTPPVHMAPGAFEGMQNGYDVESLISDELPVKAVSLWEAQQERLLARRRSAMSELALHDARVNQRGGTRSPVLHSVAMDIDDDDLSMGIKTGDAHFQQHAREYSEYQQLGGMQFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWR8</accession>
    <name>A0ABR3YWR8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">YmL10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MRPL10</name>
        <name evidence="6" type="ORF">Cpir12675_004357</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000121">
        <property type="protein sequence ID" value="KAL1892823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_uL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_uL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_uL15/eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="Ribosomal_uL15/eL18_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005749">
        <property type="entry name" value="Ribosomal_uL15_bac-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01071">
        <property type="entry name" value="rplO_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934:SF11">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL15M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="Ribosomal proteins L15p and L18e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL15/eL18" evidence="5">
        <location>
            <begin position="120"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="54"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="296"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1892823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="305" mass="33375" checksum="A3D6E8B19D8B73F7" modified="2025-10-08" version="1">MPPRLSPLMRVVLGPVPTPTLPATPVPLQLTSLLASLSLNTNARPASILSRLRDAPGAKQNTKRVGRGPSSGHGRTSGRGMNGQKVHGKVKPWFQGGQTPLVVSRGTRGFDNIRAAQLSTINLDSLQHWIDTGRIDPSKQITVKEIIESGLVGSIDDGIKLLGRGKSMLRTPVNIMVSRASTEAIKAIEAVGGRIITRYYTKDSIRNLLKGKSISSETPLPVGAEHVSQALADAKVRPWLKRLPDPTHRWDVEYYRDPAHRGYLSHMLKEGENPSLFFGVPKEMKPKKKRTGSARAKAEKDELLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXB5</accession>
    <name>A0ABR3YXB5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CBF1-interacting co-repressor CIR N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004413</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000124">
        <property type="protein sequence ID" value="KAL1892715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019339">
        <property type="entry name" value="CIR_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039875">
        <property type="entry name" value="LENG1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22093">
        <property type="entry name" value="LEUKOCYTE RECEPTOR CLUSTER LRC MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22093:SF0">
        <property type="entry name" value="LEUKOCYTE RECEPTOR CLUSTER MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01083">
        <property type="entry name" value="Cir_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBF1-interacting co-repressor CIR N-terminal" evidence="2">
        <location>
            <begin position="10"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="234" mass="25816" checksum="29B5A7156430D1D3" modified="2025-10-08" version="1">MPLHLLGKKSWNVYNKDNIARVKRDESEARAKEEAGKQRADSADAQQRLAILREENIVAVEDGDHQNNSNRTWRGGEEYARPTDSCTGPSASLGHGDRSKRPRKHANENDTDYELRLAKQNTNLAYRATTGLQPEHDQCKHTHFSGPITDKAGHIDLFGGAQHLYQHQRSTVPGHHTPRAATAQIYQDEQNQDWLKTRGGTHSSHAVAVRGESGKRGENGSGSGGGSRDALCRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXP0</accession>
    <name>A0ABR3YXP0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vacuolar protein sorting-associated protein 28</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ESCRT-I complex subunit VPS28</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">VPS28</name>
        <name evidence="9" type="ORF">Cpir12675_004262</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the VPS28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000116">
        <property type="protein sequence ID" value="KAL1893116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037202">
        <property type="entry name" value="ESCRT_assembly_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007143">
        <property type="entry name" value="Vps28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017899">
        <property type="entry name" value="VPS28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037206">
        <property type="entry name" value="VPS28_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017898">
        <property type="entry name" value="VPS28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038358">
        <property type="entry name" value="VPS28_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12937">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 28, ISOFORM 2 VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12937:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 28 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03997">
        <property type="entry name" value="VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017535">
        <property type="entry name" value="VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140111">
        <property type="entry name" value="Endosomal sorting complex assembly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140427">
        <property type="entry name" value="VPS28 C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51310">
        <property type="entry name" value="VPS28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51313">
        <property type="entry name" value="VPS28_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0967">Endosome</keyword>
    <keyword evidence="4 5 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="VPS28 N-terminal" evidence="8">
        <location>
            <begin position="18"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="VPS28 C-terminal" evidence="7">
        <location>
            <begin position="140"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR017535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="234" mass="26052" checksum="D05E742CAB6AEEE8" modified="2025-10-08" version="1">MSQQPYAPMPHSYVPNTSRSATINLDEEVKLATTRAESEVQESLAEIFSILLTLDALEKAFLKDVVPEAEYTEICERLLKQYKSILVDETIAAQFGSLDDFKAMWDLEVPRATERIRVGMPATTISASSAPSKPAAATNANGVLIAEATQEFITFLDAVKLGLLSKDQLHPLLSDVIQSVNRVTDKDFENRGKIVQWLITLNQMKATDELAEDQARELEMDIQQAYNGFKRTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXU5</accession>
    <name>A0ABR3YXU5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ams2/SPT21 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004292</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000118">
        <property type="protein sequence ID" value="KAL1893058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057725">
        <property type="entry name" value="Ams2-SPT21_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042403">
        <property type="entry name" value="Spt21/Ams2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39147">
        <property type="entry name" value="PROTEIN SPT21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39147:SF1">
        <property type="entry name" value="PROTEIN SPT21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25823">
        <property type="entry name" value="Ams2-SPT21_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ams2/SPT21 N-terminal" evidence="2">
        <location>
            <begin position="23"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="545"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="615"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="755"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="946"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1049"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1107"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1162"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1291"/>
            <end position="1312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="546"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="618"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="654"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="664"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="681"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="760"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="791"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="949"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="962"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="978"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1049"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1107"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1162"/>
            <end position="1172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1224"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1295"/>
            <end position="1312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1353" mass="146258" checksum="90CAAEA64EA0D319" modified="2025-10-08" version="1">MTSPASNWQPAGQDPFRDGEMAVKVQQMGLKVHYTFDKLDQTRCLARLPQLIQVQTLYLDEKTTVGIVDLSLCLNAVAQGSPELINACTNPNSTIDYAVYVHDYSEPEAPLVGHGMLSGLVKSQDADGTDNLAMVTGLVTRNMLAMFGKGVSHTLEVKMKFSESQKVPLITLRQTATMAASSEIQPYIENALTSAGNAEWAMLVQSNPQLTAQLPHVPTPQQSHIPSIETTSRGQSPSVVPSRVASPAVASRLSRQNSFSLPTQRQLSRQGTPVDTPTSIQQKPTAEGATPIDTTANRPPSRTSRKRGTTGRPRGRPRKNPTPSEPNGNTSGYEEGTDDDPPLKRRATTMAVAKTVNSPFSSVPESLRVAASTSGSIRTFRPVGTPEPSATGHLQDVPRAPTPVPFGDNIRPRVSGSLRRTSTLNHEQSNSQLSVVQHEDARSPNELSVGAPTPLSEASTPDFGSSPPMPRTAQYLQHSSPTPSSPILPPMPPSTNDSGFMSGGLDDFPEDNRTTPRASSRKPANIMCRDKLVPVHVFRAASGEPVDYKGSENSHAKRKRAGTLTPGSNPAVMAAGPPPPRPHYPQQAPKMLLPRLQPAPQLPDHTTQSLLLPVACNEPSSSHNGTPNTPAQHRVEAHDSDATPVQQHLHPQIPNDQRLSQPSLEKDSQGQSDAHVEPLVETSQPDRTNATTMPDLNFDLTTDLNMFSVADESLLALGDAISFDKALADIHAQQSQTPLTDIMEPLPVTQATDIPKEQRAQQPAVTPSADNIQQPLTKTSASRKPSKRKVPSPSTSTPHPTSFSEAPCPPSDVAVLLLPPAATTSPPTARFNKNYVKKQAIKERLEQAIQNGEMPPFCNNCGAIETPTWRKVFVRECMGTPVYHEYSDKPGRVTAIEVTSRDDDQTPTGYRLMKKALGPEDDKTQWRDNLLCNPCGIWLCKNNKHRPKDRWEKDAERLGQERRRRGTGRAPVRKRKTASASFAMNNMSNYPVPTSESNIMTDPLAPNDNLSPIPEAQVASRTVTANNTTMGISSIDAVLSNSGPTICQSVNSAPSASDSATQSQPSTAAPTPENEDFSGLGQTQRLLFPSQGNNNVKKDATQIHNGTSQSSVANTAPNQIDIDVQDRQPGNENRIGAEEPAIKMLATSQPTLDDEIEALFSNGSPASTINSPFTPPPPERSGVGFKTPSRPTPSHRPVTRSVSRSLRSEKSSQHSRTSPEAMPQTPSRTPKSSAISGLRVAESPSLRRSPRINRISRESGRRVLSIGGKHVEASMNDIDAALAEFSRSINDDVSSRQQNGDGSTTTLESLTNQWSPNKDWNSIFDVDMLHSLPQEDLDLLTKSLETSHGDAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYB3</accession>
    <name>A0ABR3YYB3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Trehalase</fullName>
            <ecNumber evidence="5">3.2.1.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Alpha-trehalose glucohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">NTH1_2</name>
        <name evidence="8" type="ORF">Cpir12675_004162</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:32675"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="3.2.1.28"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the glycosyl hydrolase 37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.28" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000112">
        <property type="protein sequence ID" value="KAL1893379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004555">
        <property type="term" value="F:alpha,alpha-trehalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001661">
        <property type="entry name" value="Glyco_hydro_37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018232">
        <property type="entry name" value="Glyco_hydro_37_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011120">
        <property type="entry name" value="Trehalase_Ca-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403:SF6">
        <property type="entry name" value="CYTOSOLIC NEUTRAL TREHALASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01204">
        <property type="entry name" value="Trehalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07492">
        <property type="entry name" value="Trehalase_Ca-bi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00744">
        <property type="entry name" value="GLHYDRLASE37"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00927">
        <property type="entry name" value="TREHALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00928">
        <property type="entry name" value="TREHALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Neutral trehalase Ca2+ binding" evidence="7">
        <location>
            <begin position="78"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="22"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="732" mass="83884" checksum="06405D7402EEF755" modified="2025-10-08" version="1">MNTAQRRGSADDTGALATAEEYYSSEARHGPRKRTFSQNGASRTAERLANVEPFRRGSHDESSTLQNQKFAIDVESTLQNLRDQEDTDGNMQITIEDNGPKVISLRTAASAGHNRYEVRGTYALSNLLQELSLAKEYGRKQIVLDYSRLIENPVRRLSRRIATEFWRSLTRRIDASSIEIAAKDPKDWTSDPRPRIYIPVGEERQFEYYSKVARDKPEMRLDVRMLPKNVTPEVMRDMNDKPGILALAMENHANPETGETELRGVPFVVPGGRFNELYGWDSYMESLGLLLNDRVDLAKGMVTNFCFSIQYYGKILNANRSYYLCRSQPPFLTDMALRVYDKIKHEDGAKDFLRTALCAAIKEYHTVWISEPRYDKITGLSRYRPEGLGVPPETEADHFHHILDPYAKKHNMTFQEFVDAYNFGRVKEPELDEYFLHDRAVRESGHDTSYRLEKVCANLATIDLNSLLFKYESDISRAIREVFGDRLEIPAEFCAGGMKPGEIQTSAPWDRRAKRRKMAIDKYMWNCKEGMYFDYDTVKQEQCTYESCTTLWALWAGVATPKQAAEMVSSALPRFEAVGGLLSGTEKSRGVISLDRPNRQWDFPYGWAPQQMLAWTGLVRYGFREEAERLAYKWLFMMTKAFVDFNGVVVEKYDVTRPIDPHRVDAEYGNQGLDFKGVAKEGFGWVNASYILGLNIVNVHMRRALGTLTPYEIFQAAMEKADEQTLAEFDGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYR4</accession>
    <name>A0ABR3YYR4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">UBP1</name>
        <name evidence="11" type="ORF">Cpir12675_004296</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000118">
        <property type="protein sequence ID" value="KAL1893062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02662">
        <property type="entry name" value="Peptidase_C19F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF888">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 11" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="10">
        <location>
            <begin position="145"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="616"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="627"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1893062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="653" mass="72641" checksum="5277747E400DA975" modified="2025-10-08" version="1">MRDQTSYASRLSRPSPSNKVEVLIDRLSNPQTVATIAILLIGLLYSVSNVPLRLGTYRFTLRRLFWHLVVALIPGLFLQTVDRWLNPTLDTTPMTLMLPHANKSDALSRILGLDKPGGVMASVTQARRRLSSVPSPFKPEKCKPPGLGNWDNSCYQNSVLQGLSSLESFPEYLSGPSRHGSQLPSTSATQSLLGLVADLNNSNNNGTTLWTPGILKSMNSRIQQDAQEYFSKLLDEIDEELLKVVSKSHKPLGLKRRDSRDCEVDSRAKARSKIIDGSEMRSIMGFKNPLEGLVAQRVACVQCGYSEGLSMIPFICLTLNLGTEPGACDLYQRLDAYTSVESIEGVHCAKCTLLKNKGIMSLLVEKFRASGMAEDRISEHVGRLAAVETALEDDDFDDKTLKDKCKIPAQNRVSSTKTKQMVIARPPRSLVIHINRSVFDERTFMLMKNPAPVRFPVVLDLGPWCIGSAPDGDSDEKNQSPDDEERWITKADASMAACEHSFTKVTGPIYELRAVVTHQGRHDNGHYVCYRKHSGLNKLELFEQSRIAEINPGDQDVELENLDQSELFSQKDWWRLSDETVTKCSENDVLNQGGAFMLFYDCVDEVPVRTAALEGADSLKSGQSPMKPKELTTEAIDRQFDREISDEPTELAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYX4</accession>
    <name>A0ABR3YYX4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal lysine N-methyltransferase 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RMS1</name>
        <name evidence="5" type="ORF">Cpir12675_004101</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000109">
        <property type="protein sequence ID" value="KAL1893448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1420.10">
        <property type="entry name" value="Rubisco LSMT, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015353">
        <property type="entry name" value="Rubisco_LSMT_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036464">
        <property type="entry name" value="Rubisco_LSMT_subst-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF34">
        <property type="entry name" value="N-LYSINE METHYLTRANSFERASE SETD6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09273">
        <property type="entry name" value="Rubis-subs-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81822">
        <property type="entry name" value="RuBisCo LSMT C-terminal, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="4">
        <location>
            <begin position="25"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="465" mass="51946" checksum="89197DD4E0342D34" modified="2025-10-08" version="1">MADFDQQSAAFKQWFTSIPGAEIHPSVAFKDLRGKDAGRGLVASVDIPAETALFTIPRAAIMSVATSSLVERLPELFSGEEDTEMDDEDDEMESNSPDPWSSLILVIIFEHLRSAASPWAQYFTMMPSQFDTPMFWSSAELQELQASPLVSRIGKEEAEEMFRRKIVPTIQGHKDIFYPPGTPELSEQQIIELAHRVGSTIMAYAFDLEKDENEDESMEEDGWVVDSDGLTMLGMVPMADMMNADAEFNAHVNHGEDALTVFSLRPIAAGEEILNYYGPHPNSELLRKYGYVSERHSRYDVVEVPFSMVRKQVQAYLELSDQFWEKAENFLDEDEVGESIVLERNSGDPGPDGLFQCPATVESTLDELANQVNMVLKALRKVSSSVVPDKRKREEICNEVMLRILTGCLAMYPTTLAQDRALLADKGATGRLRMAVFVRAGEKQLLEDILAGYGWSSETPDKSAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ24</accession>
    <name>A0ABR3YZ24_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_004493</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000128">
        <property type="protein sequence ID" value="KAL1892564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF38">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="374"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="48"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1892564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="455" mass="50136" checksum="35DC0C8F8F8B030D" modified="2025-10-08" version="1">MVSSSTQTDPMINTETVQSQAVSSLANGLQQLQSTKPQQLPPLVEPQGTDSKPTPAQDASSQCIQLRGMQLQSAHPIQQHAHSPQNLRDRQLSPKFPSRVPVSPKLQTCSDSSKRSVCSSAFSNNFLEHYLHMTTEILVSNTKAENPFLQYVMPLAHSDDSLMEAVLCLGGTHLCASMETPDPAVRKATLGLAFRSILISLQDEMPSSFDSIEEKLQGSMLEIYSYLVLVANITPYGLDENRTLPFDSFLFSFGERVAGLDSSGVIFSSIDGLFSLIPSVSLLARQRLEEPDNSPSAGLMRKFTELEQRINGWEPPADTAVVWDADRDSLASVYRHALLVYLKTARCGAVVGDVRVIQDVQEHVNSAIATMMSLAMSTMCAVLLWPVMIVGSCLIVKPQQNMVYEGLRYSRYKTANVLQAIELLEKLWRDPAPEAYGPYGLHYVMKKTGISLCMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ88</accession>
    <name>A0ABR3YZ88_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP phosphoribosyltransferase</fullName>
            <ecNumber evidence="4">2.4.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">HIS1</name>
        <name evidence="12" type="ORF">Cpir12675_004210</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + ATP</text>
            <dbReference type="Rhea" id="RHEA:18473"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="2.4.2.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ATP phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.17" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000114">
        <property type="protein sequence ID" value="KAL1893232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003879">
        <property type="term" value="F:ATP phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00079">
        <property type="entry name" value="HisG_Long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020621">
        <property type="entry name" value="ATP-PRT_HisG_long"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013820">
        <property type="entry name" value="ATP_PRibTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018198">
        <property type="entry name" value="ATP_PRibTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001348">
        <property type="entry name" value="ATP_PRibTrfase_HisG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013115">
        <property type="entry name" value="HisG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00070">
        <property type="entry name" value="hisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03455">
        <property type="entry name" value="HisG_C-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403:SF8">
        <property type="entry name" value="ATP PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403">
        <property type="entry name" value="ATP PHOSPHORIBOSYLTRANSFERASE ATP-PRTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01634">
        <property type="entry name" value="HisG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08029">
        <property type="entry name" value="HisG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="GlnB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01316">
        <property type="entry name" value="ATP_P_PHORIBOSYLTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP phosphoribosyltransferase catalytic" evidence="10">
        <location>
            <begin position="59"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="ATP phosphoribosyltransferase catalytic" evidence="10">
        <location>
            <begin position="121"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine biosynthesis HisG C-terminal" evidence="11">
        <location>
            <begin position="253"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1893232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="327" mass="34923" checksum="5BA26C692FB9097E" modified="2025-10-08" version="1">MDLVNHLEGRLLFAVPKKGRLNQACLNLLEGADIQFRREHRLDIALVKNHPIALVFLPAADIPTFVGEGRVDLGITGWDQVAEHDAAMRANRRAEALLSGTPVPSAETPAEGTSKPVGGCITVIPLGFGSCKLQVQVPVKGTYKATSDLVGKTVCTSFVNLAAAHFSKLENCDPSELKTKIIEIGGSVEAACALGVADGIVDLVESGETMRAAGLTAIDTVVDTEAILIKSLKPSDEKLVDKIAKRISGVITAQRYVLCQYNIESSKLSQAVKITPGKRAPTVTPLNDNDWISVSAMIEKKKIAIAMDDLSDIGAKDILVLDIHNTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZM3</accession>
    <name>A0ABR3YZM3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003969</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000103">
        <property type="protein sequence ID" value="KAL1893813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053203">
        <property type="entry name" value="Cisplatin_resist-associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022024">
        <property type="entry name" value="DUF3602"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34693">
        <property type="entry name" value="PROTEIN PAR32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34693:SF1">
        <property type="entry name" value="PROTEIN PAR32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12223">
        <property type="entry name" value="DUF3602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="141" mass="14812" checksum="68FA6AB9DA27DD79" modified="2025-10-08" version="1">MEAPKITRVGRGGAGNLQSQEFLNNCLETHESYNIPKTRESSQYVSGGRGGAGNFAAPSDNAGSLTEQLEDAVQARTRASVSSGAGRSGRGGAGNWNAEVSLETNRQAETARQKIMATIDAKVEEMVNSDLAAPPKTYSGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0F3</accession>
    <name>A0ABR3Z0F3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WD repeat-containing protein JIP5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">WD repeat-containing protein jip5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">JIP5</name>
        <name evidence="7" type="ORF">Cpir12675_003982</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat WDR55 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000104">
        <property type="protein sequence ID" value="KAL1893684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050505">
        <property type="entry name" value="WDR55/POC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019:SF20">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="349"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="351"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="392"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="419"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00039514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1893684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="451" mass="48770" checksum="E680E10F1BC800A6" modified="2025-10-08" version="1">MFESTCSLPTSSDLFCLVLHPEKPLLTVGLASGHVETFELPAPASETSTSSESTSPMPKKIALIRSVWRTKRHQGSCRALAYQKDGSRLFSAGTDGLIKGFAPETGRVFVKLALGPSDTGIKEDPSMLLVLNPSTLIASLDSAWVRQFDLENPEKNLGSLQPHEDFVTGMISLPPSKTSTSGVSKQWASTGQMTVSISDMHKGVVDESGEQDEMLICISYIPNMRARKASKTTGILVTGSDNGILKTWDPSDLEKPVHKIKVKEGESLECMVPLPESLGMGDKVACGFGDGVIRVVDLRTRKVVEDMTMSHDALSGEPVIALTVDCYGRLISGGGQIVKVWEDLADLQGNSDDEDEEEEEDNSNDGEEDVGDELKTTLNHKAKGKRSHEESSDSDADGDEDEDEDEDDESEDDSDGDDGEHATKLEQKEAAKKRKLGPMGAHGILKFDGID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0W4</accession>
    <name>A0ABR3Z0W4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C6 finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004026</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000106">
        <property type="protein sequence ID" value="KAL1893638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052973">
        <property type="entry name" value="Fungal_sec-metab_reg_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392:SF1">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="66"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="117"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="384"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="74"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="118"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="138"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="188"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="387"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="415"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="451"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="476"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="507"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="931" mass="102986" checksum="5F6FC67A603F561F" modified="2025-10-08" version="1">MSFDFNASGEAIHPLLNLGLATATATYDPQRQRYTITTATGASILPQDASTEFPVIPPTNLIAHPQSQQHLHNSLPQTQPQPQPLSTSHQNSQVQLGLHSPINIMTPQATWAMGLDLTSVSPTNSPQSQSALDEQQLHQHQQQQGHRQQFHQSQPNSQCSSPHSQNSSQHSPLAFPASLNHLPDWALQQQQQQQQQQQSSPIGHQHHSPPLQPPQHTQIPVAMTPVDAQAINDQALLGFSAFPSTFNQTPLGLLPSVTQNALGNTMAMEAYNITAMDDTIHWPNLGYESWSEIATSPLEMSPLPRGMHSVGSGSPNSAYIDVVSLPGSVSGMSESWNMVDWRNAGMIAGHPNAAIFNPGQTLHLRNHSDSDSMAQGFTGFDELSFPFSPSGSENHDASSPISQRNCYHDESQHMSHSHSHSHSHSHGHGHGHGHIHSHSQEISPDAVATPIAIKSSHSARSSPSSKSPGNGSGVITSSPTSTGTRRSSGLRKSPISKPKVVRRTSTGKKDGPAEKKVGRRKGPLLPEQRKQASEIRKLRACLRCKFLKKTCDKGEPCAGCQPSHARLWQVPCTRIDIKDIGYFMKDWNADHMRQGIPTLDAKCYSKTETLIWITHGYGFALPVMAREVLVEDEKCFEVDWVDTSNISGPKVHSVQTDRLDIGSGGVSAQVISEYLDKHVDERFTEFVDDYFDGTPFITEILKTAHSYYKKEKSPVIRKALKLVMAYNLTMHITMIENPSPEVPLEADATIESEGKKFYGRTVAPSLINVQIKNAMAEMWRELQRDVLEELSQLYSSVYSGERLKNWPTIFMLASILLAVWEEMQFDCHYRVVDPASVSKFCSDMETTPVGVIVGLFHAISQKLPAFTDWDTRKHGHILNNNPAVCEALTEVRQHVTKHESYLRGRQEAKFDANDFDSLSNKFLSKLVIKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1G2</accession>
    <name>A0ABR3Z1G2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">LSM complex subunit LSm2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">DIP2_1</name>
        <name evidence="11" type="ORF">Cpir12675_003685</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000091">
        <property type="protein sequence ID" value="KAL1894456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01725">
        <property type="entry name" value="LSm2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016654">
        <property type="entry name" value="U6_snRNA_Lsm2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13829">
        <property type="entry name" value="SNRNP CORE PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13829:SF2">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016394">
        <property type="entry name" value="U6_snRNA_Lsm2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="2"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR016394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1894456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="98" mass="11274" checksum="F1B4D0286F86F173" modified="2025-10-08" version="1">MLFFSFFKTLIGHEVTVELKNDIQIRGTLKSVDQYLNIKLENISVVNELKYPHLSSVKNVFIRGSVVRYVHLPPNHVDVPLLEDATRREAAAQREKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z217</accession>
    <name>A0ABR3Z217_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="8">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_003699</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Ubiquitin thioesterase component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. Deubiquitinates the creA catabolic repressor and the quinate permease qutD. Also plays a role in response to carbon starvation and the control of extracellular proteases activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Interacts with creA, creC and qutD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000092">
        <property type="protein sequence ID" value="KAL1894317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02663">
        <property type="entry name" value="Peptidase_C19G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF733">
        <property type="entry name" value="RE52890P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="10">
        <location>
            <begin position="57"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="596"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="596"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="637"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="654"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="691"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="739"/>
            <end position="748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1894317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="748" mass="83744" checksum="5A5C3FA6365CE2E6" modified="2025-10-08" version="1">MTSLFSRYRSSNANNSASAKEANTKKDSDESPAEITPLEKMLQPTGPVEENDADKFFGLENFGNTCYCNSIIQALFYSEIFRDRVVNYPGPLSEFNTKVEVTIRPPTVIPPPIVSKQKNNTGIALPVGGIRPEDRPDAPEYKKKQAMLKGPILELTKENTASYTMNECTFTGLKDIFLALLQSKTRTGVLSPQRFLEIFKRDNEMFRNSMHQDAHEFYGIVLNDIITNLQDHERKMSEASAPESVNARTLDASSQRSASNGAFDYGLVQDVFEGLLSSETKCLTCETVSQKNETFLDLSIDLDEHSSVTSCISKFSEEEMLCERNKFQCDSCGGLQEAEKRMKVQRLPKVMALHLKRFKYTEDFTRLQKLHHRVVYPSHLRFFNTTPQTQDSDRVYELYAVVVHIGGNAYHGHYVSVIKTKEWGWLLFDDEMVEPVDEDYVNNFFGDEDGLACAYVLFYQETTFETSRVTEEEDDSVISQLTPEEESTPISSSVFTAENGFVNMTPSTGRSSINPVADDALPSLAHVRTAPISLEALTPLENGHVYTAPVTTPTGLPTVVEDRRAEKKRLKMEKKQRDQELVAVQVAETERRKIEIAQQKQAREDMKKTMDASKGKAELEPKLRKASTGGNLLDRASWSSKSMSRKSLNFLSSKKRDQEKDKSKVPDMPPTPTRLVPNSDAIPFPPAPGGSMPSVSSNNIIINENNASLPPLPPPPPADTIASPVEKQDFRSRFSFSLGKKKSTPALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z263</accession>
    <name>A0ABR3Z263_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Geranylgeranyl transferase type-1 subunit beta</fullName>
            <ecNumber evidence="9">2.5.1.59</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CDC43</name>
        <name evidence="9" type="ORF">Cpir12675_003758</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein prenyltransferase subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.59" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000094">
        <property type="protein sequence ID" value="KAL1894277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004662">
        <property type="term" value="F:CAAX-protein geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045089">
        <property type="entry name" value="PGGT1B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001330">
        <property type="entry name" value="Prenyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774:SF4">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE-1 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00432">
        <property type="entry name" value="Prenyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Prenyltransferase alpha-alpha toroid" evidence="8">
        <location>
            <begin position="6"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="428" mass="47200" checksum="C7E85552C8011BFF" modified="2025-10-08" version="1">MEPTIERDKHLAYWNRCYKSFLPTGYTASDSTRATFGCFILSALHLLAQPSETYPSSSDFLTSEDRVRHYAWALALQHPAGGFAGSPNQLLPFSIKQTATGEPQKGPPDSSCANLAATFFALTILALVAEEDTAQYAFRDVNRVVTLSWLRRLQREDGSFGEVVNSEGQISGGRDMRYCYLAASVRWMLRGQHERGSEFWVEDINVEALVAHIRRAQTYDGGISESDYNESHAGYAYCAIAALALLGAGEDTQPSNGSLPDTITSGVRNISKLIEFLVYRQQRYLDEEDEDGDLVETPPPTTAVPTDTETAIYGHVGFNGRQNKPSDTCYCWWAGATLAILGHSNIIDSIPARRFLVDKTQHFVGGFCKAPSGFPDMYHSYLGLAALATMGDPTLPAFDPVLCCSRATVRKMIQARNGFFQHKNLSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2E5</accession>
    <name>A0ABR3Z2E5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Crossover junction endonuclease MUS81</fullName>
            <ecNumber evidence="14">3.1.22.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">MUS81</name>
        <name evidence="17" type="ORF">Cpir12675_003531</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="14">Interacts with EME1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the XPF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.22.-" evidence="14"/>
    <dbReference type="EMBL" id="JAWDJO010000085">
        <property type="protein sequence ID" value="KAL1894790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21036">
        <property type="entry name" value="WH_MUS81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20074">
        <property type="entry name" value="XPF_nuclease_Mus81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.670">
        <property type="entry name" value="Crossover junction endonuclease EME1, DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.110">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027421">
        <property type="entry name" value="DNA_pol_lamdba_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042530">
        <property type="entry name" value="EME1/EME2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006166">
        <property type="entry name" value="ERCC4_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010996">
        <property type="entry name" value="HHH_MUS81"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033309">
        <property type="entry name" value="Mus81"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047417">
        <property type="entry name" value="WHD_MUS81"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047416">
        <property type="entry name" value="XPF_nuclease_Mus81"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13451">
        <property type="entry name" value="CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13451:SF0">
        <property type="entry name" value="CROSSOVER JUNCTION ENDONUCLEASE MUS81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02732">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14716">
        <property type="entry name" value="HHH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21136">
        <property type="entry name" value="WHD_MUS81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00891">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47802">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="Restriction endonuclease-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 14" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="11 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 14 17" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0469">Meiosis</keyword>
    <keyword evidence="5 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 14" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12 14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERCC4" evidence="16">
        <location>
            <begin position="342"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="81"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="279"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="281"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU369042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1894790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="629" mass="70052" checksum="4A56435B903C9E66" modified="2025-10-08" version="1">MDDPDANSANPLFLSWVKEWLDTAREHNTKGVAVYRHAYDSLKACPITFQHPSQLDQLRGFGPKICGRLTEKLKQHCEANGIPLPQNARKRPADPGPVVDSTHGDEEAPQPKRAAKKRQYIPSYRSGAYSIVMALSSMDQSSSAAQGLTKQTVIDLAQPHCDTSFKAPPDPRKFYTAWNSVKTLIEKELVTERGRPLRKYALTDLGWETAHKLRAAATAADNAQGTKRRGKGVKQRAATAFGEQIKCLRTTSSLSDPALLSNENSYDDLAIEDHMGENCGAESQSLGNNSVGNNTEGSVIGIGDSDEDDEAVQISGAKSPSNLANLSAISPVQIPANSFSVELVLDVREVRTKTDRDYMQHNLSTLGVKPIMRSLELGDAQWIAKFHDPNLLRRLGAEGNELMLDWIVERKRLDDLICSIRDGRFHEQKFRLKRSGVENVVYIIEEKSLDSLYHKKYAENMTSAMASIQVVDGYSIKSTRSMDETVQYLVRMTNLLRRVYSKKQIHVIPSAGLTANTYLPALETLRKAEPHHGFYVSYEVFSAMTSKSDLLTLRDLFLKMLMTTKGVTAEKAVEIQKIWHTPYEFAKAYEACASEDAKRGMVLKGMCHLMGRKRVGKAASERLAEIWGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2F0</accession>
    <name>A0ABR3Z2F0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">MKL/myocardin-like protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_003987</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000104">
        <property type="protein sequence ID" value="KAL1893689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043451">
        <property type="entry name" value="Myocardin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004018">
        <property type="entry name" value="RPEL_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22793:SF12">
        <property type="entry name" value="MYOCARDIN-RELATED TRANSCRIPTION FACTOR, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22793">
        <property type="entry name" value="MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02755">
        <property type="entry name" value="RPEL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00707">
        <property type="entry name" value="RPEL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51073">
        <property type="entry name" value="RPEL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="RPEL" evidence="4">
        <location>
            <begin position="23"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="repeat" description="RPEL" evidence="4">
        <location>
            <begin position="67"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="61"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="62"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1893689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="100" mass="11000" checksum="D103F881D0E02239" modified="2025-10-08" version="1">MDTAAPIPTVDDSHIGVSPDRKNSLDNYLQHRPTRDSLIDKNILPHTTAAPAIQAHQMELQKSMRADTLNEKISHRPSPDTLLKSGVLANDPRVPSDDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2I1</accession>
    <name>A0ABR3Z2I1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003506</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000084">
        <property type="protein sequence ID" value="KAL1894811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615:SF66">
        <property type="entry name" value="CARD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615">
        <property type="entry name" value="MYOSIN HEAVY CHAIN, NON-MUSCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="131"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="888"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="420"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="577"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="759"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="179"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="224"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="890"/>
            <end position="904"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="923" mass="100462" checksum="69D53677C89AACCC" modified="2025-10-08" version="1">MFLRRFLSDTTERPQHPPRSRTPSPPPNRVKRIEMRDMPEPPTTTTYMAATTTCSTSYSAGYQPGPDPERLRDRLTRVTSNDVNFKPALPMPEEGVMGFDELRERNERLELTYEHSSTGPSNGFLPTPQMGYDNTGLPMARLPHAGIPSPPPTRPTSQNRAIENAAQGYDTNDGGGITDSDDGWAEESDSDVTASEYAPSRSSFFRHRPGTGPGSRADSGPGPGSVISRSGRSSRAVAPRRFGTKPPSYRGTLSHRGPPSNRGPPSNRGPPSDREPPSNRGPSSNKGPLSHRGPLSYMGPPSNRGPSSNRGGTRSAGPASVISVGRSPKGRVLTIQVRHPDSPAEPAPVVLSNDRTVSRRRRYPPSEAGYSYSDYGDRPLVRRDRRLMASLPTITEEEMADLRSKKDQSDAALYATLAELDKVRTELAKVKHRFRQEKRAIAREREFIGEDLNDTRDELIALHEDFAELEADAQKDQVTVSQLRSRLQKQANAFETLQKEVAEREEAVKNLEADASEKEKMMDQVTEAHEQLKILQDELEGQKLKLKVAEDPEHSNTIYGMQTSALIQVVASLQLQNKALTSTNETINSAKERLEAQLTTQKEVCVGHDEKLAELESVSEGLKASLAKFEAAAAESKNNLDAVTESKGGLEVELAAVQADLATAKAELEAAATTAVVDKSAEEAATNLAAQVSELTAALDAAKADADGFRSQLDSLNASSTDKENALAQDLEATKASLSTVEAEKGDTESKLGAATGEAEAMAAKAAGLEESLAAAQESIAQLTSSKGALDAQLAELTATNDKLQGQVDKKTNAATEIVILKQAKESLEMQLAEATAHNSRLEFEWISATKDIERLQNELTAMTNHVTLLKTEGVQYKIQIESLSDRLAKDKKKSKHHHHHSKTTRHEQLIVVRNSKPDKGHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2R0</accession>
    <name>A0ABR3Z2R0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GH16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003710</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000092">
        <property type="protein sequence ID" value="KAL1894328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02181">
        <property type="entry name" value="GH16_fungal_Lam16A_glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF24">
        <property type="entry name" value="GLYCOSIDASE C21B10.07-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26113">
        <property type="entry name" value="GH16_XgeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045988432" description="GH16 domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="3">
        <location>
            <begin position="34"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="357"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="419" mass="44560" checksum="03A5F68DFB3E4FD7" modified="2025-10-08" version="1">MSFSKIAFSVVTAAGLVSAGRTYGYPPYAPYSTSTYSTPSTPGTTGTPGTTGTTSTGATTYKMVQNYNMTNFFDNFQFFTDPDPTLGYVQYVGADISKQNGYAGYVENAVYLGADYATVNPENGRMSTRVTSKQAFTSSLIIGDIAHMPFGPGIWPAFWTFGPGWPNSGEIDIIEGVNLDTENHITLHTGPGCSITTEGSDESSVLVDANCNLNEGKTGCSQNTKAPFGSAFNELGGGVYAMDWTSNYISIYFFPRDSIPADITADAPNPANWGTPVAKFNGGYGCDINSHFIDHNIIFNTDFCGEWAGAVWTEDPELTALAATCKEYVGANPQVYAEAYWLINSVKIYESDAAQEGTPSYSSTAPTGTAPTGTVPTGLYPSSRSTTTSRVSVPYVAYPSGVMPASDPARPSVVRPFTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z352</accession>
    <name>A0ABR3Z352_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Splicing factor U2AF subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">U2 snRNP auxiliary factor large subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_003580</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Necessary for the splicing of pre-mRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the splicing factor SR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000087">
        <property type="protein sequence ID" value="KAL1894641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12231">
        <property type="entry name" value="RRM2_U2AF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12232">
        <property type="entry name" value="RRM3_U2AF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006529">
        <property type="entry name" value="U2AF_lg"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01642">
        <property type="entry name" value="U2AF_lg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23139">
        <property type="entry name" value="RNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 7 8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="259"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="378"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="486"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="67"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="138"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="156"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1894641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="586" mass="65483" checksum="41360FBEC90BE598" modified="2025-10-08" version="1">MGEGAPREPRKGSSRDYPNRGDRDSRRDRERDRDRDSHRERRRTRSPEYRGSRRRDDEPDAYSSSRSHREREREDRYSGRERRGGDREWDRERGSERSSRRERRGDDDDRSNRREREREGGFGEERRRERGGRDRRGTGGGGGGGGGGGGGFDEFPSNRERRTPSPPAKREPTPDLTDIVPVLERKRRMTQWDIKPPGYDNVPAEQAKMSGLFALPGAPRQQQQQQPDLTRLQAFVKDNTTTTPTNNATLKPTNARQSKRLLVSNLPASATDESIMAFFNLQLNGLNVIESTDPCILAQRSKDGSFAIVEFRESNDATVALTLDGTLMVDSGTENGDANGASAGLSIRRPKDYIVPDYIDDGSRERGVVSNVVPDSPNKISICNVAPYFTEEQVTELLVSFGEIKSFVLVRDRHTEESRGVAFCEYADSSSTDIAIQGLNGMELGDKKLRVQKASCGITQVAGIEMGISAMSMLAGTTAVQPDETRVLQLLNMVTPEELLDNEDYEEICEDVHEECSKFGTISELKIPRPTSGSSKQSPGVGKIYVKFETKEAAGKALRALAGRKFSDRTVITTFFPEENFEVGLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3G7</accession>
    <name>A0ABR3Z3G7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ER membrane protein complex subunit 7 beta-sandwich domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_003475</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000083">
        <property type="protein sequence ID" value="KAL1894830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019008">
        <property type="entry name" value="Beta_sandwich_EMC7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039163">
        <property type="entry name" value="EMC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13605">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13605:SF4">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09430">
        <property type="entry name" value="EMC7_beta-sandw"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045595484" description="ER membrane protein complex subunit 7 beta-sandwich domain-containing protein" evidence="7">
        <location>
            <begin position="18"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="ER membrane protein complex subunit 7 beta-sandwich" evidence="8">
        <location>
            <begin position="52"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="174"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="177"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="206" mass="21896" checksum="2619D0664AFB40E4" modified="2025-10-08" version="1">MRAVYFLTAALASIASAITSEKNDDGSSHLVSNSPISTTLLFTVPASQALANPSTLPPSTHAVLSAPGKRFSAPLTATNNFIFRNVTPDSYLVDVYCASHGFAPLRIDIDAAGQLIGAWETYRGNEWDNKGEVVQGFQTGRLEMRVLGQRGFFVERPKLGPELRAEIEEHQKGTLLGSMSSGAGSSNSGNAKARAIGNGNSEGVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3M9</accession>
    <name>A0ABR3Z3M9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">mitogen-activated protein kinase kinase</fullName>
            <ecNumber evidence="6">2.7.12.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">wis1</name>
        <name evidence="9" type="ORF">Cpir12675_003502</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.12.2" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000084">
        <property type="protein sequence ID" value="KAL1894807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004708">
        <property type="term" value="F:MAP kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013:SF25">
        <property type="entry name" value="MAP KINASE KINASE PBS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="290"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="150"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="312"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="594"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="68"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="212"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="604"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="676" mass="71981" checksum="8B048B7F8E1FD4E8" modified="2025-10-08" version="1">MSDKPNPRETLRRNSSGSETSSDNSDAPPPSDSDFTPIDATPSSPSVLSSSSADNTRRVPSLRRIPESGNSYGSTNPLNLLRTQRQPVASSGMDSLGNDTGLTTNIRVKKLMNSRSPANQSALNLGTGAGPGASAGASEGNIVGGRLGSTGIQAGSPGAGSAPPMNLSLPGRPSGPTQTQSSPLPGKISKTGSLAARRGFGMQMNLGASNMGAASSPASANGPGASDAGLGAANKPIDPRAAFIGSQIDDFREFINPEQGWLNFNGSATLTKEGVHFANGNTYSMSLNEIESLGELGKGNYGTVYKVRHAKPKQPRMGPGLSGSKPFIHHPPTEPGPDGHKFSEDGLSGTIMAMKEIRMELDKAKFKTIAKELMILHQCASPYIIDFYGAFMQDGFVYMCIEYMDGGSIDKLYKDGVPEDVLQHITLATVFGLNELKETHNIIHRDVKPTNILVNTRGQVKICDFGVSGDLVASKAKTNIGCQSYMPPERIYSNPTLETEDDGSYGVQSDIWSLGLSIIECALGKYPYDVNASILVQLNTIVKGEAPKLPEVGYSATAQDFVASCLAKNPTHRPTYTALLRHAWLASVTKPPVIQEEDEGGMENEQSNDSARNKAATETTIDTTVNAMGNMQLGTTSNLGTSLKHIQQPNDELVANWVKRQLQKKVKVKEHSKDRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4M7</accession>
    <name>A0ABR3Z4M7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Probable lysosomal cobalamin transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Cpir12675_003165</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Lysosome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LIMR family. LMBRD1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000070">
        <property type="protein sequence ID" value="KAL1895581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050854">
        <property type="entry name" value="LMBD1_LysCbl_Transport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006876">
        <property type="entry name" value="LMBR1-like_membr_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16130:SF2">
        <property type="entry name" value="LYSOSOMAL COBALAMIN TRANSPORT ESCORT PROTEIN LMBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16130">
        <property type="entry name" value="LYSOSOMAL COBALAMIN TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04791">
        <property type="entry name" value="LMBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="10" id="KW-0170">Cobalt</keyword>
    <keyword evidence="9" id="KW-0458">Lysosome</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="97"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="371"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="410"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="507"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1895581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="561" mass="62664" checksum="42C3AFF120574081" modified="2025-10-08" version="1">MQQPMLEASLIWLSYGVAVLMALAVSSITVYTWQAPRDRSLVVSSIAVISIAAFLATVLLLPVDIAIISSTTDRTLGSKKKWATPDKITEIADTLQLLYYVLYSLDAALCLFVIPFGYFWYEEYDEIEIEEGRTISSRVIGAVKSTVGFFMLAVVLLVLGYFLPTESLSSNFQGAVASLATKKVEKALDFCLSIMAVVGSLLYVTYTGVGLASLPTSFIRTAPSLSTPTFANANFRSLLRNRERQRQLELRNNGRFSSKDRRELEQLVREERTLVRRQRLAEEAQGLRRSWLQKFWLRICSTLKPLKLVGGLVMLIVSLVLCSSVLITGIDKATYALSCKSNCNYSLDNLHLFQPMDALFLWAAQSFPADYVLMTLLIMFLLASSVSGVATVGVRFLWIRIFHIRRGRTAPQALLITTIMLAMIILAINYSLVTTIAPQYSLYGTQTVCTASNFNPLGCLGRPELVVKCSSILQISGHAAHICTPSVMSTFVHRITSTWRLFGVIDLWAQFVFLFVFLLTLIILFVRAPKLNITEIDEDAEHDEEERLLARSIPTETYGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z547</accession>
    <name>A0ABR3Z547_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003608</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000088">
        <property type="protein sequence ID" value="KAL1894619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="162"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="827" mass="90216" checksum="50FF03739FED8211" modified="2025-10-08" version="1">MSLSNLATHIGLDMMDIDIDMDPVDSMLFGNLPEMLAQDLELSSNVFVSKNMTAGHPQSSLSLEPRQSTDAALDYDTEDDAMTPPPIALPLNSSSLYEVMLRVKSLGSISEASSVQESIAMLRSMNSPDSLDDGCGAVSTFSPVHPPASEPAATHKDDDSISESVYSSHSSDFAMEPPPIVRLSQPHGTSPTMNHYTLSSIISNTHTTINKPVSISSRWPVPSANSAVSIVSQKSDPDTSWIDDSEDDENILTTSNHKQPNPPLPGPQNSQKSCLFTSHSYSLASPPATPPRTGSPSFHLPSETYSSQAFRDYQPIPQAPISPPLRPCSYHHPLHQGAHLQRSESMRSSKYQQTHNDHIMGSSRPSSRASFKPSPLRDSALISTQHTSPISAEYDDPRYYLQQRQQVSSPHNANLGERLASPTLTGHPTDAMYLEDDEDGVDYNTTSTSRIEPSRPYQVAPINQIPDTIFSMHQIPSRLNTPDSWNPRGYTPEAPRVCSPSVSVQAWIENPTESHAKPIEERRVGLPLPSDVADTLRVNIACFPDTMLLTSSLTIETIRSYSRKLKHGPMIDRSKTLPRVPATNSSRKWRFSRALGSRRSANASRSICISSPVLTSAEALVPSQNPSPWVALRGVFPSASDHLCDALYAHVLAYNYVSNLCSRQAPSTLASPSHSIPSSAHSNISSLVQDSGFSHSRQQSISDSHNDIPKKAAHLLGLDAPFEIRSNSPVSSSNSRYHKKRTRIATHQAVVADISTLLMTSGSSNQGSEQAMRDLQMGLSRCIARLVVTMRCNLGTAGYAGFDEDVVEVDPLLLRSLSEIVRCCEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5K2</accession>
    <name>A0ABR3Z5K2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cell division control protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003525</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000085">
        <property type="protein sequence ID" value="KAL1894784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033308">
        <property type="entry name" value="PGAP5/Cdc1/Ted1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13315">
        <property type="entry name" value="METALLO PHOSPHOESTERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13315:SF4">
        <property type="entry name" value="METALLOPHOSPHOESTERASE, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="541"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="721"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="352"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="598"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="362"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="599"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="628"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="743" mass="83582" checksum="7DC54C30402A9564" modified="2025-10-08" version="1">MARQPRNSSNRHVNGGLDKRDPFATQHLSPLERSIEKMKDFGSHTRLMAGKCGISAATASLRKLWRYTLRALNPRRVFSFPHIMVLVWIVVLLRGERWIFYYKVNHCLWNNWEEWPADAKPHHLVFIADPQLVDPHTYPGRPWPLSSITYKLTDNYLRRGYSQLQSQLQPDSLFFLGDLFDGGREWKTEQGDFKDAPWAMPRPERDVKHAKSWLKNYGEEFWLQEYRRFRDIYLKPYGFDSFAKAAEHDHRIVASLPGNHDLGFGAGVKIPVRDRFQRYFGDSNRIDIVGNHTIVSVDTVSLSAGTSGRSSEENLRPLFEPAREFLDGVKEAKLRAATEELRFINSVTKSKVETRDTEEAAASTSQGTAEKTTVEMASTSQVNDFPTILLTHVPLYRLPGTPCGPMRERWPPAKHPKEENGRIVDPGNAISVSGGYQYQNVLSEEDSVRLIDSIGNVVHVFSGDDHDYCEVVHSDSKNNVHEITVKSINMAMGVPNPGFLMVSLWNPVDATGASQVKSTETNRLATIQTHLCLLPNQMRTYFAYIYLAVLTVVALTIRAFLVPVLHLTPFMMNSDTKGENSAAGSYLPVYKDKVEDSENSLYGGSNRVNGPPASGSVSSYSRSHPARAEAGSSRRARGMSITSGSNINSGNGGTGNGPMSRESSNGDRNKQRWGWAGKEAPRIEINRDKLYGGPQLNSHGSMWRAASARPRITVKFIIKELWASLWRIVWMVSLVFVYLTYKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6D6</accession>
    <name>A0ABR3Z6D6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">GATA zinc finger protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GZF3</name>
        <name evidence="10" type="ORF">Cpir12675_003239</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000073">
        <property type="protein sequence ID" value="KAL1895378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056998">
        <property type="entry name" value="Asd-4/GZF3_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039355">
        <property type="entry name" value="Transcription_factor_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071:SF338">
        <property type="entry name" value="GATA-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071">
        <property type="entry name" value="TRANSCRIPTION FACTOR GATA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25026">
        <property type="entry name" value="Asd-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00619">
        <property type="entry name" value="GATAZNFINGER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="9">
        <location>
            <begin position="11"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="502"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="224"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="502"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="516"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1895378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="540" mass="57976" checksum="8F8194DB747BB6E9" modified="2025-10-08" version="1">MATPANHNPQTQQQPTCHNCGTSTTPLWRRDEYGAVLCNACGLFLKLHGRPRPISLKTDVIKSRNRVKVMRNDMDGLRKKQQRLQQQTYALAPDMNSVDLGSMAQAARRAVKPGNGMHPDADQNARVTTQLYNTAGLSGFSSLEDAHFSQAALGQFQTRSGSPGLHGDGRHDSASQTHDQLIASLRTRVNELELINELFRGRLGQLEHDEANARRGQELSGVTENQLRQEIDDLLKANSDIRMQLEESHRRENALKRRLDELDVELREALDGNVEPGRKRARITEALEGTNMALATISDTCASDTHIHGLSQPEHDINGQVQSTEDTAALATRAALVASMVMGVEGLSHGTTTTVDHGVSSVQMTEGLQGNHNDQQHEQSHEHHLSTSISASMSEPMDVTPIVDEHLSTDIPGKSDLMTAVASEGVSNEASASVNAIEETMSMPIDSSMKIDPLIQESHAIALRAVADAAAAVSEAGPALATTTTTAAPEPSMAVDGNISALTPASASAPNSTSAVEESSTAIAQSLETAEQTSVETQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6R4</accession>
    <name>A0ABR3Z6R4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000068">
        <property type="protein sequence ID" value="KAL1895770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="131" mass="15255" checksum="8D5B86A75C8D3CD0" modified="2025-10-08" version="1">MYDIRPSSNPNPLYSKEKQSTGCKPSFRRRRSSFPCSSSISSKESAKFGQYLVDLYCNSQSPYPHGPQIFYSYHEFMNIDTRAKIQHKAQAAFDYSQIPQRKPHYTANDPRSSVEATDYFMDWERYVKKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z714</accession>
    <name>A0ABR3Z714_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoglycerate mutase pmu1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">PMU1</name>
        <name evidence="1" type="ORF">Cpir12675_003281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000075">
        <property type="protein sequence ID" value="KAL1895324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF1">
        <property type="entry name" value="HISTIDINE PHOSPHATASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1895324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="306" mass="34257" checksum="CC772652B390C31B" modified="2025-10-08" version="1">MPHYKFQAVPNIFVDFAPRCAADPSFKVTTQPDLAIIDRSYPGDDEAAAKLQPWERLAAYVKRLNAEAEPGSKYKIVYLTRHGVGDHNAMIRKVGQKEWDDHISKLDSVDGVLLSDARLVQEGIDQAVELSGLWSGFLGHGAPLPQSLYSSPLTRCLQTSKLVFRPLYAARNLQYRPTIKELLRERMTDHTCDRRSSKTYIAETFPEYAIEDGFTETDELWRADRWETLQAHLSRKQTVLEDIFSSDPSESISLAMHSMAVAAVGRVCGMRESRVREGTSHAILVKAVQVDASPSYSEATEGLQGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7K0</accession>
    <name>A0ABR3Z7K0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Acyl-CoA dehydrogenase family member 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_002726</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000056">
        <property type="protein sequence ID" value="KAL1896631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050741">
        <property type="entry name" value="Acyl-CoA_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083:SF13">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0274">FAD</keyword>
    <keyword evidence="4 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="10">
        <location>
            <begin position="48"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="9">
        <location>
            <begin position="144"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="8">
        <location>
            <begin position="258"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1896631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="455" mass="49952" checksum="B5225C338266B812" modified="2025-10-08" version="1">MSDRIPALARDKVNDRAKKTLDLVAKFVVDECIPADPVLNAQIGVGDARWESHPAVIEELKTKARKQGLWNLFLPTGTYSQGAGFSNLEYGLMAEWTGRSHVAAEAMNCAAPDTGNMEVLAKYGNDAQKARWLEPLLQGHIRSAFLMTEPAVASSDATNIELSIRKDGDCFVLNGQKWWSSGAGDPRCKLYIVMGKTDAKNPSPYKQQSVILVPSDTPGITINRMLSVYGYDDAPHGHGHITFKDVRVPAANLVLGEGRGFEIIQGRLGPGRIHHAMRTIGAAEQALDWMIMRINDTKRTPFGKLLKEHGVVLEWVARSRLEIDAARLIVLNAAIQMDELGPKGALKEIAEAKILAPKTALDVIDRAVQAFGAAGVSQDTPLAASWAGIRTLRIADGPDEVHLQQMGRNEAKRGTEVAETILRQKRKTEELLKAWKVERNEPGTKIRRQQNGSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7Q2</accession>
    <name>A0ABR3Z7Q2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000060">
        <property type="protein sequence ID" value="KAL1896257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="454"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="454"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="469"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="558" mass="61629" checksum="0C5EB08172FB9BE4" modified="2025-10-08" version="1">MSCNPAYWDELGPEDTSSSTSKSRDFYSRAGVPPSSTSNKAYGQSFAPQSYMDHSLLQHGRNRQNTTRIDRRHSHAIAFSQGSDRDYYDDGDIDDSVAMKRRQAPRRPRRRRSEYDEDGYFSNDSYSLEHSEVDEDSDLDYNSEDDQERVQGQRRHTTGARHRRSSRSQELTADGLNATYDPHRSNPIAIAPPPRRESYLEEQALSARGDRLGGYFPLHEDPSLRIQRSHPFHSASAKARKQSITLAQSAAAQHSAAPRSHHPSISSRLDHGSSLSASISHRRGNSYASTPKQHLEYPSSARCPDPPVAPGHSNSNSAIAWRTIHGFNTSSKPTREPGIPSMTSVDGLDKLAGQYTQLSNSNYEDVDPLDGPRPRTQPPTLNRRPPPSLSPSQEAAEQVDRPDVSSPPYTVPMGKYYPSIYEKSQESRRQAAQSMGMNPNEALYYSSDEYTDSQALPISNPVDSATHAGQHHRTTSKGHQRARSTSTYHTQNYHTPSRSLGPQSPRLNPLGSPGPVTPMDLEAHSFAAAGGGSANSYFDRSCGGAVNPKSPRDPRAHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7Z3</accession>
    <name>A0ABR3Z7Z3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein mS38</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_002672</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the mitochondrion-specific ribosomal protein mS38 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000054">
        <property type="protein sequence ID" value="KAL1896724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013177">
        <property type="entry name" value="Ribosomal_mS38_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32035">
        <property type="entry name" value="AURORA KINASE A-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32035:SF3">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08213">
        <property type="entry name" value="COX24_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01155">
        <property type="entry name" value="DUF1713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal protein mS38 C-terminal" evidence="6">
        <location>
            <begin position="319"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="35"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="215"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="56"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="230"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="353" mass="38433" checksum="02CB096E23D7987D" modified="2025-10-08" version="1">MIPSAVRRVALAAGPSPASSKTVGGTIGVSFWTLQQRRMSSSKPSSPDGSKSLSDVHTSASSRSTGSKAGAEKRKRRAKDALDRDDSFRHLPCVPSTQHMSQEAIGLSTFFSLHRPISVTHSLPKTVTDEAFAAIFSPKSKAAKVSEVISTLSSTVDKIEGPMANMEISTSHPHDHMEAAPDGATKIDVKYPDGRESSIYVQLNSMAGNFLPFQPPPIPSPQSAAEVAENATSTGPNNNSVAVTSEVDAALETDGSPQHRVYKAMFTIEETTEPDGQIRVVAHSPEIINDEAAIDGPAVTGMSRRARFEDAMKRRAPMHAISVKRQRKLKMKKKKYKKFMKRTRNLRRKQDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8D2</accession>
    <name>A0ABR3Z8D2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcription factor of the MADS box</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MCM1</name>
        <name evidence="8" type="ORF">Cpir12675_002642</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000053">
        <property type="protein sequence ID" value="KAL1896920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00266">
        <property type="entry name" value="MADS_SRF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1810.10">
        <property type="entry name" value="Transcription factor, MADS-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050142">
        <property type="entry name" value="MADS-box/MEF2_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033897">
        <property type="entry name" value="SRF-like_MADS-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002100">
        <property type="entry name" value="TF_MADSbox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036879">
        <property type="entry name" value="TF_MADSbox_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48019">
        <property type="entry name" value="SERUM RESPONSE FACTOR HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00319">
        <property type="entry name" value="SRF-TF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00404">
        <property type="entry name" value="MADSDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00432">
        <property type="entry name" value="MADS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55455">
        <property type="entry name" value="SRF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00350">
        <property type="entry name" value="MADS_BOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50066">
        <property type="entry name" value="MADS_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="MADS-box" evidence="7">
        <location>
            <begin position="48"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="127"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="184"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1896920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="213" mass="23467" checksum="2DAB3A5D1C8BC37F" modified="2025-10-08" version="1">MADITDHTDPGLPSELEDTQTLTNGDVRGVKRARAADDDDDDDEKGGRERRKIEIKFIKDKSRRHITFSKRKAGIMKKAYELSVLTGTQVLLLVVSETGLVYTFTTPKLQPLVTKAEGKNLIQACLNAPEPSSTENGGDEANQADSPEESPASQHLPPNARPAIPQQGQYPPSYMPAIDPNQAMAYQNYVQQRSTTYGMPPQTPMSQHPPHQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8K9</accession>
    <name>A0ABR3Z8K9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Malate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000050">
        <property type="protein sequence ID" value="KAL1897008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021851">
        <property type="entry name" value="DUF3455"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35567:SF1">
        <property type="entry name" value="CONSERVED FUNGAL PROTEIN (AFU_ORTHOLOGUE AFUA_1G14230)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35567">
        <property type="entry name" value="MALATE DEHYDROGENASE (AFU_ORTHOLOGUE AFUA_2G13800)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11937">
        <property type="entry name" value="DUF3455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046421275" description="Malate dehydrogenase" evidence="1">
        <location>
            <begin position="19"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="270" mass="28637" checksum="05A51A5724BDDC01" modified="2025-10-08" version="1">MKPSILYILATAVIPIAAVPSNDRDLVLNKAPLDALDAVSEYFNLLAHKIQTYKSLDSAPACSPSHATLPSSDLPEVSTNLSLIHIAIGRGTQNYTCDTPDSSSAPKAAGAVAALFNTTCPSTLYPDFNTILPKVAVHFALDDWTALDQHHLGPTGLKSSGLHYFQALNSTANAPFFSLEHIGLGSAQFSVNSSVPAPSTAAKGQAGEKAVAWLKLITRDALKASFGEIYRVNTVGGSPPSTCEGLAPKFTIEYSAEYWFYGRTSPPVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9A9</accession>
    <name>A0ABR3Z9A9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ferric-chelate reductase (NADPH)</fullName>
            <ecNumber evidence="3">1.16.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Cpir12675_002489</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2 a Fe(II)-siderophore + NADP(+) + H(+) = 2 a Fe(III)-siderophore + NADPH</text>
            <dbReference type="Rhea" id="RHEA:28795"/>
            <dbReference type="Rhea" id="RHEA-COMP:11342"/>
            <dbReference type="Rhea" id="RHEA-COMP:11344"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.16.1.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.16.1.9" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000049">
        <property type="protein sequence ID" value="KAL1897168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF24">
        <property type="entry name" value="REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="282"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="14">
        <location>
            <begin position="315"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1897168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="609" mass="67092" checksum="0CA4E2EA6E8C7D76" modified="2025-10-08" version="1">MSTTSAVDAATKTVAGAVTGASSSLSPTAGGGNATTQAMKAAAKLAAERNENLSHYLFIICGSLGFLLLVWTIVGSANRKIRHMVCLNTENQNYFSRAGTMSWFKKHIMYAPIMNKRHNREIQLSTAVNMGTLPTRLELVFLVLYFATNVIFCLLEIPYTSDTVTAFKSVRNRSGALAVTNMVPLFFMASRNNPLIVLMGLSFDSFNLLHRWFGRIVVIEVIVHTITHFIANTVGIPLSTAISTSLNVPFLRNGVIATIGMLFILIQAYSPIRHAFYETFKMLHILAAGTVVYGLWYHLKLKDFPQRPYLATAVAVWACDRSLRVARILYNNLGSGGSRTIIEALPENAVRITVTLARSWNFKPGQHAYLYFPSITLLQSHPFSVAWSESVSDSSIDRLAMTKQDALAMNKTSVSFIVRARTGATMRIFKKASAAPEGRLSTRCLVEGPYGHLPSMASYGTAMIFAGGVGVTQAIPHVRDLVIGYANGTVATRKVVLVWIIPNQDLLEWIRPFMTSILELEKRRDVLRIMIFVTRPRSAKEVHSPSSTVQMFPGKPNIETLISTEVDSQVGAMCVSVCGPGALSDEVRSATRSQQMRGEIDFAEEAFTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA79</accession>
    <name>A0ABR3ZA79_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Regulator of (H+)-ATPase in vacuolar membrane</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RAV1_2</name>
        <name evidence="2" type="ORF">Cpir12675_002293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000043">
        <property type="protein sequence ID" value="KAL1897565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052208">
        <property type="entry name" value="DmX-like/RAVE_component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022033">
        <property type="entry name" value="Rav1p_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13950:SF9">
        <property type="entry name" value="RABCONNECTIN-3A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13950">
        <property type="entry name" value="RABCONNECTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12234">
        <property type="entry name" value="Rav1p_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RAVE complex protein Rav1 C-terminal" evidence="1">
        <location>
            <begin position="611"/>
            <end position="1245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1338" mass="151192" checksum="D538645297090E37" modified="2025-10-08" version="1">MKSVLPGKSNAKLQALAIGIWGARHITVYITGNAFTILDDAQNILQTIYDDDDSELEAVAFDEILGKIATCTRSRARIYVPDNQLFLPPKWTLESTISISDPADLTTLSWGARNELLIGSHSLSLYTTDQDPQLVWHKVLSSPVYIAELSYDSAYIASCAHSDGLVKIWRRITFGSQDVRFEMTYVRHQEPVSRLQWRKPVHAGVTIENTLYTFSLDNHLRVWLPADGTQQHLQKWGSLDLDMAVEDHRLGHREKPEGMRWAFIMDERDVKTSVERALQKEGEDSTQLPQAVEHLVAVANKNPELCLVFNGEGSMSAWALENVNHATRGIQAIFNIASVVSTDLFFPGIKSDFVRISNYCDRRSGVHKIFFHYMDGRIDVYEALLTRLLDSRPFDSQKFGRLTPKATWDGHSMSITKIVRNYSGRAIVSRTNEGESFVWHYGYKKTPTPLLRQSTIPGPGAIQRICVLRKGRFVVLLRGGAVSLWDCRHKKARLMASREVEMSGRPLCLVILPRRDVKNYTVAHIATITSERKGIVWEVSFPHYNEILARSRGGDADQGSIRDFCSFDVEGEDAEGLSYVVPVDPAGESHSSFGFLDVFARDVAISYTNSGRVTFWTGRLDPNKDTVGWLATSHTETGIGNPALVSGSTLKKAALANTSRTQLTIWDIGSGRLEYNAGLQTGDAIRDLDWTSTPDKQSILAVGYQYRVVLLSQMRFDYLNKGPAWAPIREINIRDLSPHPVGDSAWLGNGHLVVGAGNQLFTYDRRIELSESLVNDLKLPKRKSGTWDLFEVVQRLSGPLPVFHPQFLSQCILAGKTAIVHIILVALCQTLKYHVEGEEVDNYLGIPMEEFYLSNKPQSMRLDIDDIGGFSSHNIHDDHEEAFSNEIALAINERLTVVKLAQLSGHEQIQLADIVECCGMVEKQRRSLDENGARFMLFFRQHVLRRGRTNEMHMSWREINWAFHSTSQDVLGDIVDRQYHGRMIWEDAREIGVFMWLADETAVRKRFEQIARNEYTKNEDKSPIDCSLFYLALKRKTILQGLWRVSSGIKEQAPTQKILANNFDEPKWRTVAMKNAYALLSKRRFRYAAAWFLLGDCLQDAVSVCLKQLKDLQLAVAITRVYEGDNGPVLKKLLEEQVLPLAAEDGNRWLASWAFWMLQRKDMAVQTLINPVYTLVETPCLPDIKSRMFLTDDPALVVLYAQLKQKTLQTLRGAAKITPRAEWDFVLHSAKLYDRMGCDLLGLGLVRNWEFSHLSHPQMKRSSIADVDPLSLVNQRRRSLVVTDIPMDELRLGGQLHENASVSSQSARPVPEKVKAAKPAPTIFYEPDANSLLDSFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAE0</accession>
    <name>A0ABR3ZAE0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GTPase activating protein (GAP)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">GYP2</name>
        <name evidence="4" type="ORF">Cpir12675_002394</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000046">
        <property type="protein sequence ID" value="KAL1897290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF20">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="285"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="717"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="859"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1115"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="859"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="874"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1119"/>
            <end position="1128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1171" mass="128158" checksum="8FCC11CD3046D3AB" modified="2025-10-08" version="1">MINFSNFVQKAQQLIDPSAGLNFGLNRSNNPDPDVNPDKATLFQAQFRLPASQSPNYEINAELVIPPSNATQGDKDHDRGYRYAGKLHLSQGFIAFSTTPSSFVQSSTLATSQLFTGQTHGGGPGGNGFTFPLCAIRRVERLNSHQFQFALAITTWNGFMLETSKAAPGPDDREQRFTIYLAGTRTACERFCDGLKRGLRDGVVNVAKMKRVAAECYSEYLMLPADKKTSSPPDAGLGLMFRYPGDAKKLRDRAKMRLWTEYLRDNGRNITLIRQPTFHKLIRVGLPNRLRGETWELTSGSLYLRLENPSLYVDTLEKHAGKESLAIDEIEKDLNRSLPEYPGFQSPEGIGRLRRVLTAYSWVNADVGYCQAMNIVVAALLIYMSETQAFFLLSTLCDRLVPGYYSTTMYGTLLDQKVFESLVERTMPVLWEHLVKSDVQLSVVSLPWFLSLYINSMPLVFAFRVLDVFFVEGPKVLFQVGLAILRINGEELLDAADDGAFISVLKSYFTRLDESAHPKSDNPKLRAVTRFQELMVVAFKEFSEITHRSITELRLKNKDAVLNNIENFAKRTALRNLGPDSKLMAPEELGALYDRFYTVLYERQQRDCILLEEQRRRGGFNAGRPGGKGRGSDSFSISSNDHSIAKGRVGLGPSTSEMDYDGFREFLANMTKWAIVDNPSTPRRETYSDREKGMFAATRKSDASVYLGPWGAGPEPADHEFMQRLFARWDSDSKGYLTLQDVVLGLARLKGKRDIMGTITYFFELYDDDSDGRVDREGILRMSEALLFLSRRGLDGTLSPTAQNNSSPPESMAAPAGSVPGIVIPGQSNNEKFLGSVSAFIRRCFEYADPDHPQNVAAREAELARQKEQRGRGESTTASSGNTNDLIDPDAFAIGDDSEDEFSDRDSPAAADKMPEIDLLTMDDSPPGSPRPAKAGLSSPSKPKRKTDRSASSQAANAALDPSNPLHITLPTFRMVVLADEMLEQFFESSLPASFHIIDGLSFAATSASSSTLTTFSSLGVTFTGAARAAASAATGSSSAAAVGPNINLNQAGRGLRGVLDNIVTNGMQVASEVQRRIEEAQKEMERAAAAGTHAGTPFATTAGLAGIPAAIGAATAHDEDDEDDDDDAQGRDLLDGADAQAGGGAGGVESEQLVDFGQEAEQGKVLEFTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAU5</accession>
    <name>A0ABR3ZAU5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">4-nitrophenylphosphatase</fullName>
            <shortName evidence="2">PNPPase</shortName>
            <ecNumber evidence="2">3.1.3.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PHO13</name>
        <name evidence="3" type="ORF">Cpir12675_002512</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>4-nitrophenyl phosphate + H2O = 4-nitrophenol + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21664"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57917"/>
            <dbReference type="ChEBI" id="CHEBI:61146"/>
            <dbReference type="EC" id="3.1.3.41"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.41" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000049">
        <property type="protein sequence ID" value="KAL1897191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006349">
        <property type="entry name" value="PGP_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01452">
        <property type="entry name" value="PGP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288">
        <property type="entry name" value="4-NITROPHENYLPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288:SF46">
        <property type="entry name" value="HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13242">
        <property type="entry name" value="Hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000915">
        <property type="entry name" value="PGP-type_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="304" mass="33215" checksum="827002437E67BFC4" modified="2025-10-08" version="1">MSQPQFISGNSAAIDKFLEGFDTFLFDCVLWSGDSMYENIPETLNMLKAKGKKIVFVTNNSTKSRNDYQKKLTKMGIQCDLDEVFCSSYSASIYISRILQLPEGKRKVFAIGESGMKEELESEGLTVVGGPADTYNRNIEPEDYQAMADKTALDPEVGVVLVGLDRKINYLKLSMAFHYIRNGAKFLATNIDSTLPSHHTFFPGAGACSIPLVHMTGETPLALGKPGQAMMDAIEGKFQLDRARTCMVGDRLNTDIKFGVDGKLGGTLMVLTGVNQKADFEAKDAVAVPAFYANKLSDLLAASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBV3</accession>
    <name>A0ABR3ZBV3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002152</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000039">
        <property type="protein sequence ID" value="KAL1897809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="734"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="300"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="393"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="39"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="130"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="746"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="791"/>
            <end position="801"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="960" mass="104395" checksum="337B17651D239506" modified="2025-10-08" version="1">MSGPENAPISPVSVPTTAKAPPPIVTRPLQTQTQRKSGSMSSASQSRPTSSSSSSAVSAPSPWIRPISRTSTAPSTSRPFSATATSTIGPSPPSSISFSPTSATHETSNAPRAPSSVTPSISVTDLAAATGTSSAPISRTTTPPMGSIVAIPPPPSATVASPGVNVASEAANQNAPKPRSLKAILQSIIATVDEVRGRQNELDDVDEILLEISELKGHLEASNAEFTALREHMTREVATYKEKKDKELKTFKETKEKELLNFKTSKTNEIDTYKARKDLEVKTFRTTKEQELESYKATRTKELEDIRTSKTKEIEELNQARLKDREEFAASRAQEIEDAIAAARREFAESHQHTEEEMDKLRTERDTAVFTKESLMAAFENRYAQWDIDTRNHARDQARVKQLEEELKNATDTMSKLSSSLTQLTTDHEKCASKDREFANNAKGLSSEVAALMVKSNLKAKEASEYKKQATDADKFRDLDNSFHDLAWNFFSRELPTPTIKLTDLPGSLWSFPQVQSNSKAAQYLRSALAEALISYKLSTCIFRQFYVPEASHVGFESMRKILEWMDQEHADQAQAIRCQLAIVSDKLPGVAYLPTATATELCNLLRPWLNPDSEAGKSFKEGLTLLMQRAMAIWQQMQRGSQLARAMVDSPEQRWLAAEDARERYSSLTLDENLQKQQAAAIALAGPEFDRPIAVLFPQIHFGNEICFSGHALFQSQACVVAARAERNATSTTAVGFMPRRRTIDASSGQRRPLTSSSNPVPSTSGGIPSSAQLEPTSSAASGVRPARPSSRQAVQSRISGFSHDGMCSSTSARGLGLGFPGHQNPNFATTTTTVAAMSSAMPATSVTNAAFNHALPPNTQSIPVMVRPLPQATGPPPVSQQDSESSFIGRLNRSPSTLRRSSVIIRRQSMAPSIAPSVASTEGTIIGGVSPIMPMYSPDFLLPSGSASMSTSYPHHNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC13</accession>
    <name>A0ABR3ZC13_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Cpir12675_002283</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000043">
        <property type="protein sequence ID" value="KAL1897555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051735">
        <property type="entry name" value="CFEM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928">
        <property type="entry name" value="CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G14090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928:SF1">
        <property type="entry name" value="CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G14090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00747">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12 15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="6 15" id="KW-0349">Heme</keyword>
    <keyword evidence="10 15" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="9 17" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047325894" description="CFEM domain-containing protein" evidence="17">
        <location>
            <begin position="20"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="18">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="101"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="101"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="143"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="155"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="203"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1897555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="271" mass="24720" checksum="1ED9643CE35D70E5" modified="2025-10-08" version="1">MKSFTTTVLAATMVATSVAQNVPACGTNCLNSMLALAPGLGCSASDTACLCRNTNFIYGIRDCSNESCGSSEDAAAAIANGVTICGSAGVELSTLTGLSGSTATGSGSGSGDSSATTTAGSDSGSDATGSGASASATGTSDSNGGGVVGGGSGSSSGSDGATATATGDSSSATGTSSGDNSSASATSTATGGDATTMSTITNSADASSTSGSDATASDGSTSSTATDGSGSSTTTTDGSASSSTGDSGSFASKFTGLPAGIFAAIAAALLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCH1</accession>
    <name>A0ABR3ZCH1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Serine/threonine protein kinase, CMGC, CDC2/CDK subfamily</fullName>
            <ecNumber evidence="14">2.7.11.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">BUR1</name>
        <name evidence="14" type="ORF">Cpir12675_001926</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.2" evidence="14"/>
    <dbReference type="EMBL" id="JAWDJO010000033">
        <property type="protein sequence ID" value="KAL1898381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004740">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07866">
        <property type="entry name" value="STKc_BUR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF233">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 14" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="30"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="337"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="340"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="415"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="458"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="484"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="546"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1898381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="566" mass="65386" checksum="E7D123CF33F932D4" modified="2025-10-08" version="1">MAASAAELDFAKAHARSRSSFVGCSRISDWEILGKLGEGTFGEVHRARSRRTGAHVAMKKIIMHNEKDGFPITALREIRLLKLLSHPNVLRLEDMSVEYPQRVGDKRKRPSMYMITPYMDHDLSGLLDNPEVTFTVPQIKCYMLQLLEGLRYLHDSRILHRDMKAANLLINNQGILQIADFGLARHYSGATPRPGMGSGPGDRDYTGLVVTRWYRPPELLLCLRKYTPAIDVWGVGCVFGEMLMGKPILTGESDAHQLEIIWDLVGSPTDVNMPGWRSLPGSEGLKLRSRPGCLATKFKDHGPQAVALLKELLNLDWRARVNAGDALQHAYFKMDPLPSKPHELPTFEESHELDRKKFQDRKAALPPAPQGGTVGRADDPNEFNSHRNGGRYNDRSTASSFNSGGDGARRPAWARGERGLPPRPPDKFDMSNGHRDRDRDRDRDYDKDRRPRNNKPNWNDRDGGGGNRDRRDDKDSYVPNYSRDGGRHRDDRDRDRDREWGGDRRDRDKDRDWDRDDRRHRDDYRDREDRDRRERRTRSRSPGLNNRDRDRDRDRDRDRDRDSYWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD32</accession>
    <name>A0ABR3ZD32_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000037">
        <property type="protein sequence ID" value="KAL1898062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="521"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="772"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="849"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="964"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="240"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="377"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="772"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="849"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="965"/>
            <end position="987"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1085" mass="114615" checksum="6F256A9298A7DA14" modified="2025-10-08" version="1">MPSKALFHKASPPSSRSRTSSASIRGKISAPIPFPDPLEDDYQLQVHLQEQKRMAGSAQSPIAPPMSIPTSIPEGQPISMPIVPNSTLAQAQARAVATETLPASPFIPSATPPLNENASESVNGAVARAVAASPSPLPPLSAEAPQNSESSQPETTKDSVADLSLPIASTRPPNSTPVPASTPTPVSIPVPVPSSTPSPAPVMSSRPLPTPSPTPTMAMANASTPHGRSYSQNQMHREGIIQSSTNNGSISSSNSGSRMSSRGRPPVPNTITRTSAATSIGTERTSKTNSTVLSSHDNAPAVASSLRGQIHGHSQSQSRSQPQLKSQKQARPDSTAARAAIPERKKSTLRSAFSRLFGKKRAKAPQPELVSKVPEGRASSIAPSPAEISRINQFQPPTRPPGTPEPKRSISLSIVDHDNAHDRALRSHSVGPNDMAAIESARNSANFESTQLQAKLQSQVQTHQQTHEPQSRPESQFQPHAQPEFQPHAQPQASPSAFFFNAKRRAASTGGDFFVPPRSFFAEPSGLSPRPASSQCRNRTPQEDEMPDGGGSELVGTGTGTGIGMGAGVGAGASRPDEIGKAITSQDILRNRRRSRSVPGIGLAQGTPTRRRSDEIRYWRQSHAGAFALSPNYNRGPMADTDNMTVRSDCGDAEPDTHAESDSARHNHSRAEAIAAVIEESQTLQPPTLRQPFDFGTITSPMKITEAVSLESRVGRVEGRLGRLEKTLNSFHHVLPGFRLTDDGARFDVGLGLGLGTSTSSGGQPNTILTATGSSIGDTSRGGTSLGDTSVGRTSFGTGTTLDDCTGIGSRSSADIRLKRPSSSQQSEDSHAAFVQTPVFLSSLHAAPAPAPRAVSPSPTSTAGPGLATEASGSITNEQYTRLLSLIEAERAARAILEAEVYRLAHALNLATSPATASGRRPTLTASTSALPLSSSAPPRNFSLHYAAGVAFNRTANETSMFYDEDTRASGDNENDTEVHRRGDGRGNHGTQGHHNMHSLYAEDSTFLTSDSSLVGATDADREDGLDSGLGGDESIMGHSILAQEAQRKTARTMSLSQLTLGRKPPFESEKRLEYEMEHAPQHAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD89</accession>
    <name>A0ABR3ZD89_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">F-actin-capping protein subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">FAC1</name>
        <name evidence="7" type="ORF">Cpir12675_002203</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the F-actin-capping protein alpha subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000040">
        <property type="protein sequence ID" value="KAL1897778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003863">
        <property type="term" value="F:branched-chain 2-oxo acid dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.60">
        <property type="entry name" value="F-actin capping protein, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.210">
        <property type="entry name" value="F-actin capping protein, beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002189">
        <property type="entry name" value="CapZ_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037282">
        <property type="entry name" value="CapZ_alpha/beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042276">
        <property type="entry name" value="CapZ_alpha/beta_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042489">
        <property type="entry name" value="CapZ_alpha_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017865">
        <property type="entry name" value="F-actin_cap_asu_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10653">
        <property type="entry name" value="F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10653:SF0">
        <property type="entry name" value="F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01267">
        <property type="entry name" value="F-actin_cap_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00191">
        <property type="entry name" value="FACTINCAPA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90096">
        <property type="entry name" value="Subunits of heterodimeric actin filament capping protein Capz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00748">
        <property type="entry name" value="F_ACTIN_CAPPING_A_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00749">
        <property type="entry name" value="F_ACTIN_CAPPING_A_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0117">Actin capping</keyword>
    <keyword evidence="4 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1897778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="274" mass="30371" checksum="FA81FE11D84F351B" modified="2025-10-08" version="1">MYSQLQIVSDFVEGAPPGELADVFADIKALTLETPDVVSKLAPAFQKYNEEQFTSVKLPGGSQSVIISPFNSLGDNSYYDIESSVSFDYDHVQQTASNVKSYMAESANIDLINSTIKSLKAYVNEHFPKAFFGAYPAENDSKVAVMIVSSKYSPNNFLSGRWRSHYLFDPITKTLEGWIKVDVHYYEDGNVRLLTNKTISNASVVSGTGAGLAKEISGVEKKYQEELNRGFTGLSEGAFKGLRRQLPVTRQKIEWDKVTSYRLGQDIGGGTTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDB0</accession>
    <name>A0ABR3ZDB0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA polymerase II transcription factor B subunit 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">RNA polymerase II transcription factor B 38 kDa subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">RNA polymerase II transcription factor B p38 subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">TFB3</name>
        <name evidence="12" type="ORF">Cpir12675_002122</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000038">
        <property type="protein sequence ID" value="KAL1898035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16573">
        <property type="entry name" value="RING-HC_TFB3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004575">
        <property type="entry name" value="MAT1/Tfb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015877">
        <property type="entry name" value="MAT1_centre"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00570">
        <property type="entry name" value="cdk7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12683">
        <property type="entry name" value="CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12683:SF13">
        <property type="entry name" value="CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06391">
        <property type="entry name" value="MAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17121">
        <property type="entry name" value="zf-C3HC4_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="33"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="168"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="168"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1898035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="369" mass="41614" checksum="257A82792C5B3B40" modified="2025-10-08" version="1">MSRKSTNAALRMTNGNTSSLPSLSSENPAEDICPVCKTSRYLNRDLEFLINPECYHPMCANCVNRIFNEGPNQCPYAGCNKTLRRKGFRQPWFNDLTIERECDIRKRVAAIFNKGEGDFETLRDFNDYLERVEDLTADMVSGVEAARIKAEGELIEWENAHKAEIEANRRRRGEAEERVRKNQQADQERSRQLRLQAQQEDQAEKAAERKLREEQLNAIANGEMGKATEALNRIALKKRGKDAIVGAHGGAGSTASALSIRGLKDKKKRRGADFEDTSKPYDPFGGLDLIPLRFQMHEPKTYHNEWINAARAKDEFRIGGYNADDYIKRTMFEAFSGLAVFVEEEQPAEILTSEAEAEAVEAPATTVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDC1</accession>
    <name>A0ABR3ZDC1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nuclear protein localization protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NPL4</name>
        <name evidence="10" type="ORF">Cpir12675_002095</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Perinuclear region</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NPL4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000037">
        <property type="protein sequence ID" value="KAL1898076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08061">
        <property type="entry name" value="MPN_NPL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016563">
        <property type="entry name" value="Npl4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007717">
        <property type="entry name" value="NPL4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007716">
        <property type="entry name" value="NPL4_Zn-bd_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12710">
        <property type="entry name" value="NUCLEAR PROTEIN LOCALIZATION 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12710:SF0">
        <property type="entry name" value="NUCLEAR PROTEIN LOCALIZATION PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05021">
        <property type="entry name" value="NPL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05020">
        <property type="entry name" value="zf-NPL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010052">
        <property type="entry name" value="Polyub_prc_Npl4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0811">Translocation</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MPN" evidence="9">
        <location>
            <begin position="259"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="598"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="604"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="618"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1898076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="698" mass="76375" checksum="6CC8A4713EDE231B" modified="2025-10-08" version="1">MLLRVRGPDGMIRVNVEAEATFGDFGGLLVPQLPDTVDPYTIALSNSPTGADSKLLEELSTISISRVGMKHGDLIFISYKHKGAASAPSSDNLADSADSGSVTARLNGKAIVQETPSAQETVAMVEGAARPWELIKQSPLDDKLDKLPGTIPRSRNSMCKHGPKGMCDYCTPLEPFNPIYLSENGIKYPSFHAHLRKINAATNKPESGTSFIPPLSEPFYRVAPNCSGGHPKWPIGICSKCQPSAIILQPQNFRMVDHVEFASPSIINTFIDAWRRTGLQRIGILYGRYAEYAKVPLGIKAVVEAVYEIPQVDEVDGLTTNDWTNESNVDNVAKMCGLEKVGVIWTDLLDAGKSDGSVVCKRHAESYFLSSQEICFASCLQAKHPRVTKWSRQAVFGSNFVTCVISGNENGEIEISSYQMSNSAVEMVRANIIEPSTEPAVMFVQEEEEEDTAIRSRYIPEVFYRKINEYGANVQENAKPSFPVEYLFVTLTHGFPEAPKPVFLGSGFPIENRSHVGISQDHTDLAKALKITHASAKPAEVHDVSDFHLLCFIKDLDILSEDELSTLCKAAVSHNQSVMYDASATSGWRTLQAILKSTGERIPKRQRASSAHRHDRPYYSQSSSRPSDLASSSSSSDAPTPLSSHSSTSSASASHDSLAPSSTLFAAPEDQQPLAKRFAAVRLNNENRPRRSNPPRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZED1</accession>
    <name>A0ABR3ZED1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vacuolar protein-sorting-associated protein 33</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">VPS33</name>
        <name evidence="2" type="ORF">Cpir12675_001875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000032">
        <property type="protein sequence ID" value="KAL1898410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.830.10">
        <property type="entry name" value="Syntaxin Binding Protein 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043154">
        <property type="entry name" value="Sec-1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043127">
        <property type="entry name" value="Sec-1-like_dom3a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043155">
        <property type="entry name" value="VPS33_dom3b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="677" mass="75406" checksum="802BED43805FF3A9" modified="2025-10-08" version="1">MSSQPGFSTDQIRERARKALLNLLEGVRGKKNAIIDRSLVGPIGAIVKVTTLQEYGIDKFFVLENDNADTSQHNVVFIARGESGRHASMIADQINRLRRESQIGHDFHIFWVPRRTLVSDRLLEESGVMGDVTISELPLSFFQLERDVLSLELDDAFHDLYLTKDTTPLFLLSRALMEIQQTHGLFPRIIGKGDNAKRVAEMLDRMRQETLAGQDPTDKTRQRLTPSTKIESVIIVDREVDLVTPLLTQLTYEGLIDEVFEINHNQAKIDTTVVGAQAPTSGASSQTRKRAIQLDSSDKLYDQLRDANFAIVGSLLNKVARRLQKIQKDYEVKQSSQTIAELKEFVGNLPAFQAEQQSLRIHSGLAEEIIKHTRAELFKGLLEVQQNLAAGADPSSQFDTIEELIARDTPLKEVLRLLCIYSCISGGIKPKEYDQFKRLILQSYGYQHLLTLTNLEKLQLILPKTSPLSNVIPLSANAGVPGEKTNYQYLRRQLRLIVDEVKEDDPTDIAYVYSGYAPLSVRLVQCVLQKQYLNSFAKASGTGTSVPAPIPAAVGGAGQSQGWHGFEETVKHVRGPTFCQTQKGEEDKAAKARALLSGAKERQTVFVVFVGGVTFAEIAALRFIAKQEEGSYLFTCNKRDIVICTTSIVSGNRMMDAAIETRSYAKKPAQPTRDTTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEG8</accession>
    <name>A0ABR3ZEG8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Inositolphosphotransferase Aur1/Ipt1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_001779</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000030">
        <property type="protein sequence ID" value="KAL1898672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03386">
        <property type="entry name" value="PAP2_Aur1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026841">
        <property type="entry name" value="Aur1/Ipt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052185">
        <property type="entry name" value="IPC_Synthase-Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31310:SF16">
        <property type="entry name" value="INOSITOLPHOSPHOTRANSFERASE AUR1_IPT1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14378">
        <property type="entry name" value="PAP2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Inositolphosphotransferase Aur1/Ipt1" evidence="6">
        <location>
            <begin position="119"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="330" mass="37883" checksum="C2462FDA2E3619BF" modified="2025-10-08" version="1">MSAALRNSVEPLSIVLSFTIGSIINRRRGDSHFYERANAQEGGKGGITTSYWNSGGQNEKSRNTFWSLLGRFFNKFPFLIEIWYWNLSYWVYQLLRAISARMIAGNQAIFERAQGHALQVLRAEQYLGIAIEQPFQQYVLTQHPWLMSILAKIYYSHITVGVCFLVYMFKYVPAPTYQRIRRTIAMNNAIAFVIITVWRCYPPRLLPREYGFVDILHSAATSATAANVWNNNRFQLTIAAMPSLHFGTSLYLAVCICRFSPHRMLRILAPLWPTAMLITIVATANHFLTDAMVGAMIPLLGWRWSHVFLRLLPLQERLFAPIARNLPKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF98</accession>
    <name>A0ABR3ZF98_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Extracellular serine-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001590</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000026">
        <property type="protein sequence ID" value="KAL1899034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052953">
        <property type="entry name" value="Ser-rich/MCO-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883:SF17">
        <property type="entry name" value="CUPREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883">
        <property type="entry name" value="SERINE-RICH PROTEIN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046540149" description="Extracellular serine-rich protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="220"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="245"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="291" mass="32236" checksum="C6E00CB20E21C1E4" modified="2025-10-08" version="1">MRFIATSLLAASAVLAVPTPPNNEIEASPDWNPMIIPINVYPNAFDFSVNYARPGDILQFHFMPGYSSVVESTFEKPCSPRKFGFSVAPIEVNYYEALDVFRVVVLDYNPIWFYNGASNQCNEQGAVGVVNPPWPYDQPFYDFREAAREQTETIDPRINANGFFAPNPRFRHNQPKPSTDENTEEAENTEDGSKEPETSQAVNSEAEQAEALETEEAKMAEAQMAEEAQEAALARQKEKGKQVAEPEPTTPEETNTPQEAAKPERTRKKVSFAPSLHSTGNGESSSSTTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFR9</accession>
    <name>A0ABR3ZFR9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA-splicing endonuclease subunit Sen34</fullName>
            <ecNumber evidence="4">4.6.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SEN34</name>
        <name evidence="8" type="ORF">Cpir12675_001669</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the tRNA-intron endonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.16" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000027">
        <property type="protein sequence ID" value="KAL1899009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000213">
        <property type="term" value="F:tRNA-intron lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd22363">
        <property type="entry name" value="tRNA-intron_lyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036167">
        <property type="entry name" value="tRNA_intron_Endo_cat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006677">
        <property type="entry name" value="tRNA_intron_Endonuc_cat-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016690">
        <property type="entry name" value="TSEN34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059049">
        <property type="entry name" value="TSEN34_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13070:SF0">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13070">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN34-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01974">
        <property type="entry name" value="tRNA_int_endo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26577">
        <property type="entry name" value="TSEN34_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017250">
        <property type="entry name" value="tRNA_splic_SEN34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53032">
        <property type="entry name" value="tRNA-intron endonuclease catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TSEN34 N-terminal" evidence="7">
        <location>
            <begin position="11"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA intron endonuclease catalytic" evidence="6">
        <location>
            <begin position="193"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="109"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR017250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF26577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1899009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="283" mass="31463" checksum="86104F33C0B6AF75" modified="2025-10-08" version="1">MTIQNDPDPARISLIGGRYLVFDYKQISQLRRDHNLCAILVGTTPQNPSQNVFQGVPLEIGPEEATGLVSIGAAYIVDELQAHLNALDSSDLTFRDTYLKDLASRRRQLSSALDQEDQRKKQEAQIYRKSGSKGSQTLKPSDPGLELETKVDATIEDSKPPLTSLTTAHSFTLISPPHDPSISHKPLVDPLWRWLQSNGYYMTPGLRFGSHYSVYPGDPLRYHAHFLANSYPWDKPVPLLDLVGNGRLGTAVKKGFLIGGQYLDENGQSKGPFRAFTIEWAAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH10</accession>
    <name>A0ABR3ZH10_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001272</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000019">
        <property type="protein sequence ID" value="KAL1899690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024312">
        <property type="entry name" value="TACC_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615:SF63">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_10, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615">
        <property type="entry name" value="MYOSIN HEAVY CHAIN, NON-MUSCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12709">
        <property type="entry name" value="Fungal_TACC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="75"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="326"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="599"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="685"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="465"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="149"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="342"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="709"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="820" mass="88118" checksum="54F08454F7A0E481" modified="2025-10-08" version="1">MTIPLTLATESSLNIASSISATPASSTGLLSPSALSLTTSSTSSATILPCKRPFGSGSASASSLDMVITDRLTEAQSAASVSPNNENHTHLQSQSRDSQPRPDHRMSRVMSGTELSPLKLLGGGDVRSPSACSTGSTGSGSGDNNFRTSISSSHPISPSEKTVRSPRKFPEKRFPVRVTSPSSNTRTRAGSEATTSHSMSPDRPTLSIGEALLDNGNLAKAIQIFEDEDKAMTTPPASLNSSTDGAANGFNNDHDAIMEDDESTVANDNDVSNYSNFSAIRLGQSPDIQDQAAARARGSSPMYHPTSSGGNTTNLLMDFTDNLRHPHGSLNKTPSRRPVSMMPSTSSEYSQASNAYPPTATPGRQGGNLLDFDIPPMPTPRSIPSVTPRELESLKSQFLSEISSLKASLLGKEAEVQSLKAAVGDAEKRVGESMDQMREERTMRETLAVEKEGWEHRGRELETVLRKLREDYATTHRKREEFESKLNESEGRREMAEMMAQEAESKMAGMRAGQQQLQAAAAQATAPGAPKGIASRSPAAATAREVEVAVERVARELHTLYKGKHETKVAALKKSYEVRWEKKVADLETKVMELEQENDRLRGSHHGQTPKVDPAQVQAEEERRAQAAHDQATLRQLEAEVDKLEAVLREVSRDNGDLRQMLEQERVEKGELVQLAEEMMAMQASMPALQQQQQQQQQYGHQDRHEQVPRTPAKPAARSPARSSTGNITAPRPPSAASASSTGSGGNGPSSSNLRTPAKPRPMSMIATSSMSRPSGLRAPGIAGRGGVVERGKPGGAIMPRPGATRSSMMPAMPGQRRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH20</accession>
    <name>A0ABR3ZH20_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">37S ribosomal protein mrp51 mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016712">
        <property type="entry name" value="Rbsml_bS1m-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28058">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN MRP51, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28058:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS1M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11709">
        <property type="entry name" value="Mit_ribos_Mrp51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="416"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="461" mass="51353" checksum="B01993B1004B15A0" modified="2025-10-08" version="1">MATQRVSPGARLLRTSRMFSMPKPLPVAHDSVANIYATPTTATAPYPTSQAISSPLSSRAKGDWGLKRPLPLKTTLNTTTPMIRVKAIDAVEKITDFNSAADHGLTLQKFQELGVALTMPVSHIHRVQSGKVSVFEEDYDFTAINEKPNDVSHKRWKFKGPWLGGMTEGQFKKYLISLRQRKPEFREFVRAKLAAEVTQNEAREAMEQGKGTVPPPKTASEISEEMLNDYFLRLRDDSARFNIYSYVSEFLDLAPIAPPNQGSKEADVVVRPVSPYANEGPPKCHPSAGLSYLRTSQFLSNHPLYGPQKYRLTRARILSPWKGSEVPKLGVAGVITDIPLGQNRFNVRTPAKIESEMSNVPGILNFNPEIVGGAKVHVNPKIARVDSQGRIILTVDESQPECNMVYEELQGRKKVYHRDPKERAAEKAASESHPVPHRRPKKLYQHQANVLGSVQNYGLGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH51</accession>
    <name>A0ABR3ZH51_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">IRC5</name>
        <name evidence="7" type="ORF">Cpir12675_001139</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10799">
        <property type="entry name" value="SNF2/RAD54 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="113"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="617"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="15"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="385"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="455"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="385"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="407"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="485"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="508"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1900033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="848" mass="96201" checksum="7C1110B08907C752" modified="2025-10-08" version="1">MATIDLDTLQLEEEKARLENEATRSNQKAKRKPRRTNSKKEREDKARDLDALLRQTEAFSNILTAKTKALGRVGTGFDGQSRVEHKLAMAEQPQCMIGGTMRDYQLEGLTWMYEICEQGMSGILADEMGLGKTVQTISLIALLREKDNYFGPHLIIAPLSTLSNWMKEFEHWVPSIPVVMYHGTPPERADIWAKQVTKNYKSGRPTAKFPVICTSYEVTLRDRAVLSKIQWEFIIIDEGHRMKNFDSKLFRELKTFQSATRLLITGTPLQNSLKELWSLLNFLLPHIFTDWDAFDTWFDFSDLQDEEGTEEFITNSENHDIMKKIHVVLQPLLLRRVKADVAAYLPKKREYILYAPMTKEQTDLYRAINDKEVDTREFLQNKVMERLANEETPKPRRSTRSQVKNKQSAENHEEKPPVLRAAEETLAIRQSPAKKANTDRPAKNAFAMLMGNKTTNSHASKATSKTEAKPPPPTPSKKRKAPVAKAEDDPEPKSARSSRQSTPAGGRAHSRLRRGVKTYKESEIDDDALSDDQFEAELAKEIQVKEMDEIESIQNSEDFEYAKTLELAKKEVSSKKLGNPIMQLRLVCNSPHNFYHPWNGSDPVDETIITASGKMLLLDRLLPALFQDNHKVLIFSQFKSQLNLLEEYCALRDWECCRLDGSVAQSDRQAMIADFTTRTQLRIFLLSTRAGGQGINLMAADTVILFDSDWNPQQDLQAQDRAHRIGQKNPVLVFRFATRGTVEETLLTSADAKRRLEKLIIKKGNLETLTQSVSGQMSNKLDKETLRSLLLKDGRVYEYSGGEYVLSDADVATLCDRSDEAYEKASKGGGNADAFTVVETGVNGIRQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH83</accession>
    <name>A0ABR3ZH83_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001121</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37451">
        <property type="entry name" value="MARVEL DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37451:SF4">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="289"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="306"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="364" mass="39041" checksum="E66E37E4FE27FCDF" modified="2025-10-08" version="1">MTMPQSFTPVYPSQAAGQPPAQEPTGQHYYQSPPQQAQQAMAAPGPAAAPAYAAKSPCLIIDTPAWVVVVFSVIMGLTLPILGLSARVMHDLYLDCNGLSLAISIMTWLAVGYVVLTEKMPALRGYYHIYLVIAVNLFMTLMWLVTMAVVAHKRAQFKYPVTLDDCSSDGSFLNSTTCSILKRWYVQVLTKTGLAMEVAIACLSVLQMILYLAVSIWFLKTYFDSRNTVATTMAMVTGPSAVEAQHYVSAPQQPEKQDPMAAAAPPPVYNAPVAAPLPVPSVPVAPAMHQQPHAAADPVSPPAPPLSSVSPVSWSAVMHSPTPPPPMAVPSDVSELPSRAQQQMNPPVEMYAAHTQGPSQGHNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHM7</accession>
    <name>A0ABR3ZHM7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-histidine N-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.85</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_001297</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the methyltransferase superfamily. METTL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.85" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000019">
        <property type="protein sequence ID" value="KAL1899712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF39">
        <property type="entry name" value="HISTIDINE PROTEIN METHYLTRANSFERASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="29"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1899712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="392" mass="42264" checksum="0B8729E327C98598" modified="2025-10-08" version="1">MSFSFSFSGDDIDEDVSIDTPSVISAALATTTSDDHTNRKESNDGRPQAGAFPIEGKPQLPALAHSLDEMMAMLPSKIAYNTLRITLDEGPDVIELPRRELWDVKVQLMAEDDSEGDSNATEGLGAHDVKTGVYEGGFKSWESSVDLIKVLASERYGIAGPGKGKVERVIELGCGTALPSLAIFQQALQRFTSATPDAELQPLTLIVSDYNPSVIQLVTLPNFILTWALARRTVDPVLEEALSIEDEVELFDEVKAAFKKTLSDAKLSLVFLSGGWSTAFVDLLYATAPLRSDALDASAVGAKESLPTLLLGAETIYSPFALRAFAATQFNILSKEGKEALALIAAKRHYFGVGGSLDDFITKATDDGATVEWLREEKDGVRRGVVQCKTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIA8</accession>
    <name>A0ABR3ZIA8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carboxylesterase type B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000912</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046656210" description="Carboxylesterase type B domain-containing protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="2">
        <location>
            <begin position="36"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="206" mass="22789" checksum="82179E727F6B8367" modified="2025-10-08" version="1">MRFTDALFPFLIINCLSLISDTTALPRRSKHRKDMPILTLPYGSFRATYESNTDIYIFRNVPYAAPPVGNLRWRKPQPPVTKSGIQDGEFGPHCPQGVVSGFNIIGPGNRYPAGKAINQIFGGVTLPNFREANEDCLYLDLYVPGKALMDGETLPVVVWVFGGAFVVGSKDIYQPFLPWYDGSGLISQSGNNVIFIAFNYRLGSFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZII4</accession>
    <name>A0ABR3ZII4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">La domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_001132</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12291">
        <property type="entry name" value="RRM1_La"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045180">
        <property type="entry name" value="La_dom_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006630">
        <property type="entry name" value="La_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002344">
        <property type="entry name" value="Lupus_La"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792:SF140">
        <property type="entry name" value="ACHILLES, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792">
        <property type="entry name" value="LUPUS LA PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05383">
        <property type="entry name" value="La"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00302">
        <property type="entry name" value="LUPUSLA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00715">
        <property type="entry name" value="LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50961">
        <property type="entry name" value="HTH_LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="HTH La-type RNA-binding" evidence="7">
        <location>
            <begin position="101"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="202"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="286"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="39"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="323"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="346"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="363"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="381"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="427" mass="47081" checksum="C9666DD2C5CF93D4" modified="2025-10-08" version="1">MADAENTIVPPAAEVVEQPTEATPTEAVEATTAEAVETTTDEAVETTTDEAVEATTTEAAEAAEASTETPSEALIEKPDVLKTTASVNEDYSKNNKFDPSVLPETDNADEIRRQVEYYFGDFNLPRDKFLWDTTAGPENKPVPLKTLHTFKRMRRFQPYSAVVAAIKESTLLNIEGEEGEEGIRRKTPYKPSPERRQKSEAATIYAKGFGDENPNSQFEIEAFFAEHAPVNGVTLRRTPEKLFKGSVFVEMASEEAAKAFLEKKPQWKGHDLKLMTKKAYVEEKNELIRSGQMKPGNSAKPFFEGRGGDKPSRGNFRGGRSGGNKDFKGDSNDWKNRRNHDRKNGFRGGRGGRGGRGGRGGRGGRDNRDRDSKPEARDNGKGNNTNDVKLPSIQATNDKGEPVNNNKRPRDDDCSEAPPAKKVEVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ72</accession>
    <name>A0ABR3ZJ72_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sensitive to high expression protein 9, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">SHE9</name>
        <name evidence="13" type="ORF">Cpir12675_000772</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Required for the maintenance of the structure of the mitochondrial inner membrane. Involved in mitochondrial morphology. Causes growth arrest when highly overexpressed.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion inner membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the SHE9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008839">
        <property type="entry name" value="MDM33_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31961">
        <property type="entry name" value="SENSITIVE TO HIGH EXPRESSION PROTEIN 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31961:SF3">
        <property type="entry name" value="SENSITIVE TO HIGH EXPRESSION PROTEIN 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05546">
        <property type="entry name" value="She9_MDM33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="465"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="75"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="389"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="182"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="249"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="75"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1900758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="502" mass="55215" checksum="7B0E070EDB065A66" modified="2025-10-08" version="1">MHALLRPGIRLSLGAVRAANGSSGMQPSCIASLATRARLARSGVGMRLYSSQKPPSDSDFDIEKSPFAHLLKKPATSLASSETPATPATTTTDAATADNSDPQTTASSQPQHPSSPTPSSSSTASSSDDSTSLPFNKDQIHRNLKDTRQVLSERFSVFMDNVQSRVVHASETLNVLTGYTPIETIKMANAQLETSLAEAQSQVRACRIQYKTMNARRAATQREVTTLLARKDAWSPTDLERFTQLYRTDHEMESQVSQASESLTEAEAEEQSLSTRLNQGILRRYHEEQIWSDRIRRASTWGTWGLMGVNILLFLGLQFIAEPWKRNRLVKGVVAEEKAVLEEVRDRLDHVMKTMEENLATAHALAYPPTPAPATEAVPEAASERATLAQEPSGDDAVLADEPSENQRPLSPSYTTSGPIQLYFPMPANVDWSWEEFLRSPKLWRNLAEDFYSDRRVDMRMRDSATLVLEGMAVGTVITAAVTALAMGAGTGFPWNLLAVFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJB7</accession>
    <name>A0ABR3ZJB7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Potassium channel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_000785</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003280">
        <property type="entry name" value="2pore_dom_K_chnl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11003:SF301">
        <property type="entry name" value="POTASSIUM CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11003">
        <property type="entry name" value="POTASSIUM CHANNEL, SUBFAMILY K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01333">
        <property type="entry name" value="2POREKCHANEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="37"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="205"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="261"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="383"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="416"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="445"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel" evidence="11">
        <location>
            <begin position="210"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel" evidence="11">
        <location>
            <begin position="393"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="641"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="675"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1900771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="744" mass="83597" checksum="97CFD98F19B5DF42" modified="2025-10-08" version="1">MASDVDPVVQEPRETHDVATKRLFIPKDGDFMWPSRWWFASSAFPMIAGTLGPVASAFSILALSRPWRQHRPPGTSIDGAPFIGDPVWLIAVNAVQLGMALTSNVFLLLNMARRVRFVVAQPVTIVGWFASSFCLVGLSATASGPLLDATDYPADEIMWSQAFYYGIFAALLYFLVAALMCITVHGAATNNYPKDFNLTTSQRTLMLQSILILLYLLLGALMFSQLEDWSYLDGVYWATVTLFTIGFGDFIPTRSVSRGLLIPYALVGIISVGLVIGSIRSLVLERGQSRIDSRVLEKKRRRMLRTLLKNGQDEILKPITESELGLYPTDSPVTTNAEPALAKEAPAPGHVLSTAPITELQRRKAEFDLMRSIQEQASAQHRWMGMATSFSLWLILWLVGAKIFQETEHASQNWTYFDGFYFTFVTLTTLGYGDRTPKSNAGKAFFVFWCLMALPTMTIMISNASDTVVRVVRDVTISVGNITILPGERSFRAEVKWFISRATFGALWSDCYDQTYLYDQDHDNSPIGGYTDCKLPVPPHSTLDAEHAILQQATGDSGAQAHAHLRPRSVVAARMRNSFSTLRHPTTPLPRGKYLHFILSSEISSVAQHAQAKREKHYTYEEWTWYLKLLGEDESDARTHAVARKHAPITKEAPGGNQAVKKEHDGHGYGSSSGRRQRRRHRKRHNDDDMPPEDWSGWSWVGINSPLLSNKSESQWILENLTERLRRELYQELVQREEGRDGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJR2</accession>
    <name>A0ABR3ZJR2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mannose-1-phosphate guanyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">GDP-mannose pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">GTP-mannose-1-phosphate guanylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_000932</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in cell wall synthesis where it is required for glycosylation. Involved in cell cycle progression through cell-size checkpoint.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>alpha-D-mannose 1-phosphate + GTP + H(+) = GDP-alpha-D-mannose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
            <dbReference type="EC" id="2.7.7.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; GDP-alpha-D-mannose from alpha-D-mannose 1-phosphate (GTP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.13" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06428">
        <property type="entry name" value="M1P_guanylylT_A_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056729">
        <property type="entry name" value="GMPPB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050486">
        <property type="entry name" value="Mannose-1P_guanyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22572">
        <property type="entry name" value="SUGAR-1-PHOSPHATE GUANYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25087">
        <property type="entry name" value="GMPPB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleotidyl transferase" evidence="10">
        <location>
            <begin position="19"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Mannose-1-phosphate guanyltransferase C-terminal" evidence="11">
        <location>
            <begin position="314"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF25087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1900462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="444" mass="48935" checksum="C3CA0EC73BE4D3F4" modified="2025-10-08" version="1">MSLQVPIRGGKPASQGATKAVILVGGPSRGTRFRPLSLDVPKPLFDVAGHPIIWHCVKSIAEVPNKQISEVLIIGYYEENVFADFIKDARKEFSGLNIKYLREYEALGTAGGLYHFRDAILKGHPDKLFVLNADVCCSFPLAEMLKMFYDKDAEAVILGTRIDEDAATNFGCIVSDAHSHRVLHYVEKPESHISNLINCGVYLFSTEAIFPSIRTAIKRRTDRPRLLSYPSSDKLETNFTVNTDEDESDAQKIIRLEQDILSDMADNKQFYVYETRDFWRQIKTAGSAVPANALYLQKAQLARDPELTTPSANIIAPVFIHPTAEVDPSAKLGPNVSIGPRAVVGAGVRIKDSIVLEDSEIRHDACVLSSIIGWGSRVGAWARVEGTPVSATSHETQIVKNGIKVQAITILGKDCGVGDEVRVQNCVCLPYKDLKRDVANEVIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKR6</accession>
    <name>A0ABR3ZKR6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_000708</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="2-AMINO-3-CARBOXYLMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240:SF28">
        <property type="entry name" value="ISO-OROTATE DECARBOXYLASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="4">
        <location>
            <begin position="104"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1900832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="375" mass="40767" checksum="013195F2A83202F2" modified="2025-10-08" version="1">MATYTSPVVDIHTHMYPPSYLSMLEERTTIPLVRSFPGANEPRLILLEAEIENLEKAGKDAAIGLPGRPLTSHYASLEQKLHFMNTHKIDISVISLANPWCDFLKPENAAPQTRATNVEFSQMCAAHPGRLYFFATLPLTAPIDQLLEAITELKTLDYCRGVILGTSGLGSGLDDPKILPIFSQLAQNKLPVFLHPHYGLPNEMWGPRASAEYGHVLPLAMGFPMETTIAVTRMFLAGVFEAVPDLQMILAHSGGTLPFLAGRIESCIMHDGHLVATNKTSLGRRSLWTVLREQIYLDAVVYSPVGLKAAIDASGADRVMFGTDHPFFPPLKTDPQGEWESVSLNAEAIAQAASLGAQGAIMGDTAARVLNLTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKU7</accession>
    <name>A0ABR3ZKU7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Mitochondrial carrier C19G12.05</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_000793</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049563">
        <property type="entry name" value="TXTP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45788">
        <property type="entry name" value="SUCCINATE/FUMARATE MITOCHONDRIAL TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45788:SF4">
        <property type="entry name" value="TRICARBOXYLATE TRANSPORT PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="19"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="109"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="206"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1900779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="303" mass="32499" checksum="E343C230B46D0D27" modified="2025-10-08" version="1">MSTSGAAPTAPVADQKKRPSALRSVLAGATAGAIEISITYPAEFAKTRTQLNRRLADGKKLPWPPFGAQWYAGCTTLIIGNSAKAGIRFVAFDQFKSLLADENGKLSGPRTVVAGFGAGVTESLLAVTPTESIKTTLIDDRKRAQPRMRGFLSAVPIIARERGIRGFFAGFVPTTARQAANSAVRFTAYTSLKQLAESYTAPGEKLGAAGTFAMGGLAGLITVFATQPLDTIKTRMQSIEAKTMYGNSIRCATLIFKHEGLLTFWSGAMPRLARLVMSGGIVFTLYEKAMDLMNKIDPEMKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLA0</accession>
    <name>A0ABR3ZLA0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tim44-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="315" mass="35596" checksum="8F095377778BE4E3" modified="2025-10-08" version="1">MASRFGPLLVARPAFAGSRAAAATVLPPFTALSVRWNSGYSRESSQMNKRMQSQARTSKSPVVEQRSRMEMMDGRAKDMLMPGTFIALPFNKLSWGDLSKYQWERCKNWAQNYFYRLSLSWASKPGIFKPAVLKYESRSQLVQTALSLQRDVNVAMASGDEAALRRLCGMVLYGSFAAALARRRPRETYLWERQQLHGSPAVVSSRLMQMPTDNGSLRQMVVVRIASTQVLGRVDPLSGSVIEDSKKVHRKSENLMMFRAIDSCSYEKGPWYLYGYLPDTTPEAWLRDAAHMEALQMQAVKQYKETRGKKAAVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLE7</accession>
    <name>A0ABR3ZLE7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000407</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="228"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="419"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="437" mass="48155" checksum="DC06CE107876D34E" modified="2025-10-08" version="1">MPSYQIPLPPAPGRKPEPVCTPAADQTSGLSHVSYPAAAVIYHASILFAAKFPDLPFVHLPSVARDCTSLARPKIQPSVGVQTVRAAVRALYVALVGLVAPLMGGEGTTSGQIVLWVDMARETAMAGLHLPDVVLVQTLAVLAMREWGLGRAHEAWMYSDHAHLLAVEGFDIWYDVLRWVVSGGRRRFPHESPWELDAAWMKLRERLRLWRRRHGRRLCFPETSVETVLWLGLTVTAIVAGSIPLLCCGLMNSICWNMRLFSCDYDLRDMLPAHEFESQSQYSGTGPRTRCCVPRRVLPHLASGNGWWTTIHQLKELYQRASRDGHAFQGGKPRNDYLRFESSIHDPTGMPPEQHSHSPNIARMDRDDTSMSTVAHGKPATPENNQNQQPPATSDSVRPEANPDASAEADPEANPTDIVGNNQAAVSTAQTAGFASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLG7</accession>
    <name>A0ABR3ZLG7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tuberous sclerosis 1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000424</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007483">
        <property type="entry name" value="Hamartin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15154">
        <property type="entry name" value="HAMARTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15154:SF2">
        <property type="entry name" value="HAMARTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04388">
        <property type="entry name" value="Hamartin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="456"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="768"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="929"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="640"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="468"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="489"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="768"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1013"/>
            <end position="1025"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1038" mass="115549" checksum="D1AE441047B18FA2" modified="2025-10-08" version="1">MAPNGSFKELCQALNAFIINPTLPLPEDLNAVFDAFYRKHDKYDDSNADRLQDELQVIWDKHVASDPQRYAPFVAICSRLFQALHTTERIFYWWDLTLQHMANQMIKDKSLQAESYQALLQLLVAENDQDQTSEDDAAAETASRSMPFLDRLLHTWLFGDTEIPSDLCHQLGKHQQTVLVSFGKKKPRELMACLNKYFVRAEFRLKCLILLNDLVQTQSPHLHLVLQTPLFGNLLACLENDASTTVINLGLTLLVMLLPNMPTSLIPYLPALFNVYARLLFCNRGRHDSAVSPPASKTASIDSPLPSITSNDSWDICAFDPQRDGRDVPQLCNYFTILYGLYPINFMDYIRKPQRYLRHANAPSANWFEIQSTEIRQLSERFRCIHVLHPNFYSLTIESEKTDFSRWLSSNAAELVTDCMSLCIPSTQPIVTCNDEVPVGKSLANYMANADCSIDSPVSDSPIEKTECSGSSLLSNSPDDYESAEESALAQTSSEDTGISIGAESSTCVSQNHNEPKPTPSVACDTSHPENLTPTQDNEYKGKAESFDSSGIAHQIFMLQNELRFEKYLKQQHSAHIGVLRRRLHQQAASEAETQNLIIMNRHYKKRFDEAKVAETMAKKDYERGRSLSMKRETDMMAKNKILREDLRARKAEVETLKRDIEAYKAEADRLTKLMCALEEKDLAQKQDQEDMEMTHQEMKHLKSEIARLGQSALDKAGRDAEVQAAIKARDEAEAREEICRMKLEACQKDFEQQRRTFDKQIMALQTRLSTENSTGRTSGRHRSESQTQEAITASLAASRAKQSELQKQYAVLVRKYTALQSSMFDAPLPSPVQITPKNLAQPRVSYLEEGIEDATTPAGVGAAISGGHHYIGGDIPPPTTHLYHASSQARHHGSSPGPWPLHRVFSNPDLSDSASVSSRSPQLLHAHMHSHHASGSVGGYGYPLPSRHPGAGHRQFSADSSSFGGGGGGGSASASISGSIGGGGSGHTEVATPSSPLVQQRYHGRGGVQSKFRKEDKKKDEGSKKKSSGFRGIRGFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLL4</accession>
    <name>A0ABR3ZLL4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycosylphosphatidylinositol anchor biosynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">GPI8</name>
        <name evidence="7" type="ORF">Cpir12675_000621</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000008">
        <property type="protein sequence ID" value="KAL1901132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028361">
        <property type="entry name" value="GPI_transamidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001096">
        <property type="entry name" value="Peptidase_C13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48067">
        <property type="entry name" value="GPI-ANCHOR TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48067:SF1">
        <property type="entry name" value="GPI-ANCHOR TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01650">
        <property type="entry name" value="Peptidase_C13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500138">
        <property type="entry name" value="GPI8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019663">
        <property type="entry name" value="Legumain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00776">
        <property type="entry name" value="HEMOGLOBNASE"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045634641" evidence="6">
        <location>
            <begin position="23"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="326"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="341"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="418" mass="46883" checksum="70D0F16D6671134B" modified="2025-10-08" version="1">MKFPVLQGLLALSLMAAQPAIAAEHTSNWAVLVGTSRFWFNYRHMSNVLSIYRTVKRLGIPDSQIILMLPDDMACNPRNAFPGTVYSNSDRAVDLYGDNIEVDYRGYEVTVENFIRLLTDRVDPEMPRSKRLLTDDRSNILVYMTGHGGNEFLKFQDAEEIGAFDLADAFEQMWEKKRYHEILFMIDTCQANTMYSKLYSPNIIATGSSELDQSSYSHHADNDVGVAVIDRYTFYNLEFLENQVQDMSSKKTVGELFDSYDPAKIHSNPGVRYDLFPGGAPEARSRLITDFFGNVQNVEVQGTRNVSLEMEMVQLSKTIAELRRLADEEDAQEDKKHKQQSAHSSFSSSPRASSSSSVAGSHFKALVAESIRQPQKKVIRLAPATPLEEGNWWQKKIVGATVVAGCAALWSISAYLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLM1</accession>
    <name>A0ABR3ZLM1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Signal recognition particle 54 kDa protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">SRP54</name>
        <name evidence="15" type="ORF">Cpir12675_000303</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Signal-recognition-particle (SRP) assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum (ER) membrane. SRP is required for the cotranslational protein translocation for ER import and preferentially recognizes strongly hydrophobic signal sequences. It is involved in targeting the nascent chain-ribosome (RNC) complex to the ER and is proposed to participate in the arrest of nascent chain elongation during membrane targeting. SRP54 binds to the signal sequence of presecretory protein when they emerge from the ribosomes. SRP54 interacts with the scR1 RNA and mediates the association of the resulting SRP-RNC complex with the signal recognition particle receptor (SR) via its alpha subunit SRP101. Both, SRP54 and SRP101, are locked in their GTP bound forms in the SRP-RNC-SR complex, which dissociates upon transferring the signal sequence to the protein-conducting channel (translocon). After signal sequence transfer, SRP54 and SRP101 act as reciprocal GTPase-activating proteins (GAPs), thereby resolving their association.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.4"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">Fungal signal recognition particle consists of a 7S RNA molecule (scR1) and at least six protein subunits: srp72, srp68, srp54, sec65, srp21 and srp14.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 13">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="13">The M domain binds the 7SL RNA and the signal sequence of presecretory proteins.</text>
    </comment>
    <comment type="domain">
        <text evidence="13">The NG domain, also named G domain, is a special guanosine triphosphatase (GTPase) domain, which binds GTP and forms a guanosine 5'-triphosphate (GTP)-dependent complex with a homologous NG domain in the SRP receptor subunit srp101. The two NG domains undergo cooperative rearrangements upon their assembly, which culminate in the reciprocal activation of the GTPase activity of one another. SRP receptor compaction upon binding with cargo-loaded SRP and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the GTP-binding SRP family. SRP54 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17875">
        <property type="entry name" value="SRP54_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="entry name" value="Signal recognition particle SRP54, nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.30">
        <property type="entry name" value="Signal recognition particle, SRP54 subunit, M-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00306">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036891">
        <property type="entry name" value="Signal_recog_part_SRP54_M_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004125">
        <property type="entry name" value="Signal_recog_particle_SRP54_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022941">
        <property type="entry name" value="SRP54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006325">
        <property type="entry name" value="SRP54_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01425">
        <property type="entry name" value="SRP54_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 54K PROTEIN SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564:SF5">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE SUBUNIT SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02978">
        <property type="entry name" value="SRP_SPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47446">
        <property type="entry name" value="Signal peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 13" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 13" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="8 13" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="10 13" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="SRP54-type proteins GTP-binding" evidence="14">
        <location>
            <begin position="281"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU364034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1901613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="560" mass="59700" checksum="2F0BBDAA2FF77BBB" modified="2025-10-08" version="1">MVLQDLGRRINGAVNTLTREPNVDEQASSRRFANTRSLAFEGMVKDICGALLEADVNVRLVGQLRKSIRASVNFKEIPPAVNKKRLIQKAVFDELVKLVDPHAEPLKIKKGKSNVVMFVGLQGAGKTTTCTKLARHYQSRGFKACLVCADTFRAGAFDQLKQNATKAKIPYYGSLTETDPAVVARDGVQKFKKEKFDVIIVDTSGRHRQESALFQEMIDIQSAIKPDETIMVMDASIGQQAEAQALAFKTSADFGAIIITKTDGHAHGGGAISAVAATNTPIVFIGTGEHMLDFERFVPQSFIQKLLGMGDIMGLVEHVQNLNLNQKDTMKHIQEGIFTVRDLRDQLSNIMKMGPLSKMAGMIPGMSNMMQGMDDEEGTLKLKRMIFICDSMTEAELDSDGKILTEQPTRLTRIARGSGTSVREVEDVLTQQRMMAGMAKKMGGSMKTLQRAQSAMGGANSKSQMAAMQKRMAAMGAGGAGGAGGLPGMGGLPGMGGGMPDLSSLMGMLGGGGGGGGGGGGMPSMQQMQQMMQQMGMGGMGGMPGMGGMPGMGGRGRGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLW5</accession>
    <name>A0ABR3ZLW5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein ECM13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000714</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037738">
        <property type="entry name" value="Ecm13-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36826">
        <property type="entry name" value="PROTEIN ECM13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36826:SF1">
        <property type="entry name" value="PROTEIN ECM13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="291" mass="31010" checksum="82E7ABA3364B459D" modified="2025-10-08" version="1">MISSPSSKPIRSSPQASSSSADSTSPASSISSVSSVSPVSVNRSTMSMTQTYYLAHRARSKLGAEASRSDHNLRVLVGHANLLDTLMLELAEAEREQETWYHNSPVSSSKSTSTTSTSPSQARHIQWADQHISQGDSDSDSSSDDWDVSSTEDEESDDEDFADHIPETSSSLHRMPKNAAAGSFSPSVVTISAVESDSDSDSEFDDDEDLSQLSLVRTPSHSGSASGSPPELALDCDLDDSSDDEADMPPSPPTAIIDIYRASSKSSGKESLFLTVPPRSPSRLVSNVSVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM41</accession>
    <name>A0ABR3ZM41_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Adenylosuccinate lyase</fullName>
            <shortName evidence="2">ASL</shortName>
            <ecNumber evidence="2">4.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Adenylosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ADE13</name>
        <name evidence="4" type="ORF">Cpir12675_000287</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + fumarate</text>
            <dbReference type="Rhea" id="RHEA:23920"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>N(6)-(1,2-dicarboxyethyl)-AMP = fumarate + AMP</text>
            <dbReference type="Rhea" id="RHEA:16853"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.2" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03302">
        <property type="entry name" value="Adenylsuccinate_lyase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.30">
        <property type="entry name" value="Fumarase/aspartase (C-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019468">
        <property type="entry name" value="AdenyloSucc_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004769">
        <property type="entry name" value="Pur_lyase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00928">
        <property type="entry name" value="purB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43172">
        <property type="entry name" value="ADENYLOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43172:SF1">
        <property type="entry name" value="ADENYLOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10397">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00998">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Adenylosuccinate lyase C-terminal" evidence="3">
        <location>
            <begin position="373"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="484" mass="54903" checksum="74093F8F9C9CA4ED" modified="2025-10-08" version="1">MVKYDSYETPLGARYASKEMMELFSARTRVSTWRQLWVWLAEAEKELGLDFTEEQIQQLRDNVTITDEGFKIAAEEEKRRRHDVMAHVYAFGQVAPKAAGIIHVGATSCYVTDNADLIFLRDALDLLLPKLAKVIDNLAKFAMEWKDFPILGFTHYQAAQPITLGRRVCQWAQDLMMDLEDIEHVRAELKFRGAQGATGSQASFMEVFKGDEEKIDKLNQILCQKAGFSAIYDISTQTYTRKVDLRVANAISALGATAVRIAADLRHHAHDKVMDEPFESTQIGSSAMSFKRNPMRSERICALGRKLKTINANFADTFSNQWFERTLDDSAVRRMDIPEMFLLADSILLSLDNVTNGLVVNEAQFREQLGQELPFMVTENILMRMVQLGISRQDAHEEVRVLSHQAAKVVKQEGKKNDLVERMKSNPFFAPIKDEIDEMMDPKLFIGRSAGMTERFAGPNGVLDKKLQPYRKFLNSASTAELNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMZ1</accession>
    <name>A0ABR3ZMZ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_000401</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF8">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="330"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="397"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="428"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="465"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="22"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1901532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="557" mass="60893" checksum="B6AFB087A9276959" modified="2025-10-08" version="1">MPLGELQFHTIKACFNWNIAYALLIFGLMGSSRGLDEGLIGTTVTLPSFIELFDLESTDLSASQRADRLSNITSMLQLGSILGAVLAFYVTDRLGRLWASRELCLVWMAGISIFLAASRTGNLGMVYAGRFIAGIGVGQTTVVGPTYLAEVAPPAIRGLCVTVFSGFVYLGIMIAYFASWGCSLHISDSSKAQWLVPNSLHLMFGSIILFGSFFAVESPRWLAKVHRTSAARANLSRLRGLPTGHPDIESEMADIQASVAIEENAKEGSSVLTLLRELVTKPANRSRLGLSIAVQFLSQWSGASSITIYAPEYFAMMGVSGSNEKLFATAIFGVVKFVSSMLCAFVLIDFIGRRRSLLAGISLQLLSMFYMALFLVIDKEASVEGSYQSSSQKRAAMGAIVMIYISGFGWALGWNSIQYLINSEIYPIRLRAVGGSIAMTVHFANQYGNSKAVPHMFVGMAEYGTMFFFVAVTAIGFLWVYFFIPELAGLPLEAIDAVFELPWWKIGRKGREAVTQAIDEKDRAVCKDIYEVEVIEDEKGPNPHKIEVLEANVNSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN74</accession>
    <name>A0ABR3ZN74_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">LisH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_000211</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12610:SF12">
        <property type="entry name" value="SEQUENCE-SPECIFIC SINGLE-STRANDED DNA-BINDING PROTEIN, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12610">
        <property type="entry name" value="SINGLE STRANDED DNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="32"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="136"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="269"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="379"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="471"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="33"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="275"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="383"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="517"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="580"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="664"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="704"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="732"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="768"/>
            <end position="777"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="866" mass="91752" checksum="C0703B31EAFD0516" modified="2025-10-08" version="1">MNSANLNIGGMNPMAGGPVGATVPMMNQGAMVMGQQPQPGHQSQPGQPQMQQPPQGPPQQQQPQQQQPQQQQPGQQPMMQQQQQQQQHVGARPLVTDPQHRMILNTYIYDYFIRFGMHDCALPLVKNGEYHVQTVNDENRNNNDENAEGDSKEDVKAQGDLPDPRLPMSSETSFLLEWFAVFWDIYGASKGSTKNINPYVSQYVNHTQSQPRMRQVSQHDLLRQVRDGSTPQMYSNLMRMSNNGMTMMKSGAPLARAAIANSNGQMMLQQQKHGMPREGGMDANRDRPPSPGASENVPSPSKKVRVDGGFNPSQSNMMMNARPAGMIPGPQGPGGPNGQANQQILMAGGMNPSSMTPQMQQFGSSNQPKSIATYAATLQQHHGQQMPGKQIPGGPQGQGSPMMPQGPDGGPMGNMYPGGEMSQGPMRPNQPGGPNGAGGQSNHALQDYQMQLMMLEQQNKKRLLIARQEQDSMGGPRGDGQNPPGPGPNGQPYPEASPQNKTGASPNPGDIKRTAGPMNNASIPSPATVDGQNQGSPNPMNFIGGEQMNGAMNHNFMVAGNQMNGGMRPPSSHPQYANGQMAQQQIMVARQQQQQQQQQQQQQQAGGQNNQGQWQQNGMNGNQMMQPGQQQNQQQGGPQLSQGQGAPIQGTPQQRAVMAPPSAPNTVNSRTNTSSPQQGTPAPPTPQQIVKAAPKKKETKTTKTKAAAQKKAGTAAGATPVPESAEVDAPTPATPITPANPPGFKPNVASQSNGGIQPPIPNSQAPSVPSGVAPPTGAGSGAGVGAGAGAGAGAVTQAHADPSFNVDANNNMVNFPSFELADPLNGDNVLENFDFDAFIQTDGDNNEAFDFGVGFTQIEGGEIGAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPX7</accession>
    <name>A0ABR3ZPX7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Vacuolar protein sorting-associated protein 1</fullName>
            <ecNumber evidence="7">3.6.5.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">VPS1</name>
        <name evidence="7" type="ORF">Cpir12675_000433</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.5" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019762">
        <property type="entry name" value="Dynamin_GTPase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003130">
        <property type="entry name" value="GED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF220">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02212">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00302">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00410">
        <property type="entry name" value="G_DYNAMIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="6">
        <location>
            <begin position="33"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="5">
        <location>
            <begin position="605"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="535"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="692" mass="76549" checksum="58BB64B3144CF9C2" modified="2025-10-08" version="1">MSSLSSGGISDPALIQLVNKLQDVFATVGVNNPIDLPQISVVGSQSSGKSSVLENIVGRDFLPRGSGIVTRRPLVLQLINRPSGTNNSADDISTDGDKAANADEWGEFLHLPGQKIYDFNKIRDEITRETDAKVGRNAGISPAPINLRIYSPNVLTLTLVDLPGLTKVPVGDQPHDIERQIREMVLKYIGKSNAIILAVTAANQDLANSDGLKMAREVDPEGQRTIGVLTKVDLMEEGSDVVDILAGRIIPLRLGYVPVVNRGQRDIDNKKPIQAALENEKNFFENHKAYRNKSPYCGTPYLARKLNLILMMHIKQTLPEIKARISSSLQKYTSELESLGPSILGNSANIVLNVITEFTNEWRTVLDGNNTELSSSELSGGARISFVFHELYSNGVKAVDPFDVVKDADIRTILYNSSGSSPALFVGTAAFELIVKQQIKRLEDSSLRCVSLVYDELVRILTQLLNKQLYRRYPGLKEKMHGVVISFFKKTMEPTNKLVKDLVAMEACYINTAHPDFLNGHRAMAIVNERHNPSKPVAVDPKTGKPLPNQAPVRTGSPSVDLESNTGFFGSFFSSKNKKKAAAMEAPPPMLKASGTLSDRENIEVEVIKLLIASYFNIVKRTMIDMVPKAIMLNLVGFTKDEMQRELLENMYRTDTLDELLKESDFTVRRRKECQQMVESLGRASEIVSQVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRL7</accession>
    <name>A0ABR3ZRL7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000032</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="565"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="417"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="471"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="420"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="586" mass="63704" checksum="0EAA6897A2538DE2" modified="2025-10-08" version="1">MSMQPQPSSRSVSTHHRLASVVVHPPVSLHPPSVYGSGPARIRSWTRPRIAPPSTGPPLLGSRRLLFGCKFIVRRPSSGSSDGLQPEIGIHGPILKPVSQIDRAEAWGVDIPPLPELKPVFLWPHLRWELRHMAGQDAADMPWVRPSDGIYLNWVPLSATRKDVFTFSYGNGLVWCVKKKPVKILRIVQSNAHKGGGGSGSSRGSCGDDGGGYSGDRQSTTMARPRMKKANLTPPSSTGATSRDISHPPASRLLLSLEPTVKSHKSLTARGLHLLVKSLGFDDPSTTHKGSNHGNSMLANPPRKLSSNSNFDETESESIADTLFSIPSPGTSIPDDLLSIASDQPQEVDMEPFPSYDDSGFVFPDLPENGAVCTSACCKSDASPEISLDISPVASPQANTTQLPPLELSRRLTELEVTLSRCPPSASASSKRPSRSARSSRIITSPQRRSPKRSKLPPSWLELAAAPSFSPKKAYDPTPYKSPGERRKKARKKMKDRASVLVSGNGGEESESRFVPNPTARPSPRPCKKPHPKSPTEEPERFPLLVDEQTRKGDLNTWEPSTTGLLFGVIAMVFLCFWMVDMIYSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YCY2</accession>
    <name>A0ABR3YCY2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Class II abasic (AP) endonuclease</fullName>
            <ecNumber evidence="8">4.2.99.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">APN2</name>
        <name evidence="8" type="ORF">Cpir12675_006958</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000454">
        <property type="protein sequence ID" value="KAL1885993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004808">
        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020847">
        <property type="entry name" value="AP_endonuclease_F1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020848">
        <property type="entry name" value="AP_endonuclease_F1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748">
        <property type="entry name" value="AP ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748:SF4">
        <property type="entry name" value="DNA-(APURINIC OR APYRIMIDINIC SITE) ENDONUCLEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00726">
        <property type="entry name" value="AP_NUCLEASE_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00728">
        <property type="entry name" value="AP_NUCLEASE_F1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51435">
        <property type="entry name" value="AP_NUCLEASE_F1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="7">
        <location>
            <begin position="3"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1885993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="391" mass="43442" checksum="0D3CA61B6B715809" modified="2025-10-08" version="1" fragment="single">MFATLDADIIVMQECKIQKKDMTDDMVLVPGWDAYFSLPRHKKGYSGLAIYTKTATCAPIRAEEGISGVLCPPGSATSYRDLPKSLQIGGYPSHSQLLDGFDEAALDSEGRCVILEFPAFVLFGIYSPASCDQDRAGFRLSFFHALDLRIRNLVALGKQVIVAGDLNVSRDIRDSCGIVSALAKAKIKIEEYMNDDLRRIFNQQVFDGQVCGSRDAERQEPVLRDLCREFHPERPDMFTCWDTRRNTRPANNGSRIDYVLCSDGLWKWIVGADIQPGLMGSDHCPVYADMSDTLTEKGVTHNLLDLMNPEGVFSRGVRLKQWSTADCLAQSARLMPQFSGRVSIKSMFKRHQSHERKTAMGPCKEGQVVVGALKKSGITASICESPVDLQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YE32</accession>
    <name>A0ABR3YE32_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_006877</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000401">
        <property type="protein sequence ID" value="KAL1886062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007567">
        <property type="entry name" value="Mid2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04478">
        <property type="entry name" value="Mid2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045130201" description="Mid2 domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Mid2" evidence="4">
        <location>
            <begin position="184"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1886062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="306" mass="30928" checksum="FDE7B0AFAC638993" modified="2025-10-08" version="1">MYTPRLVHLLLVSLGFIFVVHASIFNLHAPGRYGNLLRRQDDSSSASQTTAEPTTAAETSTPEAATSSSQSESVAPTSSPTSALTTSVVVTPSTSTASPPSSTSLAVATSTPQTTASDSPQSTSTNDSAESSSAADSPTTTSSDDAATTTPASSDDSSSSDDTPTARVSTTVVVITTTDDSGALVTSTSISTTTQTASPADDGDNGSSGMSTKTRNTVIGLAVGIGGAVILGAVGFVAWRIWGNRNNSDEADGLMSNNNTGYHVMETSAAPRTTSSPVAGAPARNPFQSTLETYHAPTQVNASSNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFH8</accession>
    <name>A0ABR3YFH8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006717</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000359">
        <property type="protein sequence ID" value="KAL1887049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="201" mass="21740" checksum="7E42F443C69A6946" modified="2025-10-08" version="1">MLLFPLPISGERNRESKEHAQRAERNRIHASSSYRIPTASDLGPENEVSGLPWGSINIGHVVSRGLDDASRRSNSYAGRPSAAEAEASARRIFGSVSPVPAALSSHPPPERAPTSVPCSSASTSPGQTSQAQTQAQGQPQEGYPQNAFRPSGLIPMPAPTPQSTGAEQFSMPWFQDVAELIYHAPENHKNQNQDRSRKQDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFS8</accession>
    <name>A0ABR3YFS8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DL-glycerol-3-phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">GPP1</name>
        <name evidence="1" type="ORF">Cpir12675_006665</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000345">
        <property type="protein sequence ID" value="KAL1887168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07527">
        <property type="entry name" value="HAD_ScGPP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051806">
        <property type="entry name" value="HAD-like_SPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43481">
        <property type="entry name" value="FRUCTOSE-1-PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43481:SF4">
        <property type="entry name" value="GLYCEROL-1-PHOSPHATE PHOSPHOHYDROLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01135">
        <property type="entry name" value="C1.5.6:_HAD__Beta-PGM__Phospha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1887168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="234" mass="25512" checksum="23E8359EEBB7E859" modified="2025-10-08" version="1">MPYTTESAQATFDGFLFDMDGTIIDSTEAIVNHWKVIGEEIGIPAEVILQTSHGRRSYDMLKILKPEIASWDYVCKIEGRIPEKWGDSAVEIPGARDLINVLIKNSAPWAIVTSGTKPLVSGWTKRLNLPEPKVLVTAESVDNGKPDPQCYLMGREKLAMADTNKQILVLEDSPAGIRSGKAAGCKVVGLVTSHTAEQVAAAGPDWIVEDLKSVAVVKNENGVVTLEFSRLWKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG19</accession>
    <name>A0ABR3YG19_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 14">Chromatin-remodeling ATPase INO80</fullName>
            <ecNumber evidence="14">3.6.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">INO80</name>
        <name evidence="19" type="ORF">Cpir12675_006695</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="14">Component of the INO80 chromatin-remodeling complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="14">The DBINO region is involved in binding to DNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="14"/>
    <dbReference type="EMBL" id="JAWDJO010000354">
        <property type="protein sequence ID" value="KAL1887103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18002">
        <property type="entry name" value="DEXQc_INO80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020838">
        <property type="entry name" value="DBINO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031047">
        <property type="entry name" value="DEXQc_INO80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050520">
        <property type="entry name" value="INO80/SWR1_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685:SF2">
        <property type="entry name" value="CHROMATIN-REMODELING ATPASE INO80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685">
        <property type="entry name" value="HELICASE SRCAP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13892">
        <property type="entry name" value="DBINO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51413">
        <property type="entry name" value="DBINO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0010">Activator</keyword>
    <keyword evidence="7 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9 14" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="19" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="DBINO" evidence="18">
        <location>
            <begin position="720"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="16">
        <location>
            <begin position="968"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="17">
        <location>
            <begin position="1540"/>
            <end position="1699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="250"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="545"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="595"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="790"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="846"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1736"/>
            <end position="1822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="55"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="158"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="203"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="213"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="260"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="303"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="328"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="360"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="374"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="389"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="402"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="550"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="608"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="620"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="662"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="846"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="1736"/>
            <end position="1746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1758"/>
            <end position="1769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="1797"/>
            <end position="1813"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU368001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1887103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1822" mass="206114" checksum="6C32001015331DBB" modified="2025-10-08" version="1">MRDLMNPQPSTPSSTSHHIPGFSLRSPPPKADYRQHTSASSYSTTDTHHNRHHLTSSTTPASQYSFASSAYRDPLPGPPPASVPTPAQRTSPMRPPPLYAPPRASAQAPALARREGSGFYDPTSDSIAPESRSWNESTSKPLDPFDLPRNTHSESRSSHQSHYASPQQSTSIHSAHHSLSRPPPLGGLTVGSPPRRPRDGEPSDTSSPTMSRSNGTSSSGGLPSLLKPASPTLPARSANVMSFSNILTSSEPIAKASLADIEHGHERERERENDREHERGRDCELPSLRERDQPARSFTPLRESTKSRKADSPHAQESSILAPPDIDVGMETEYPVETEAEIEPESEVLDESDAPVKIKKDSRRKSSVKKIRSRVNDIKDSEPSKSRRSSANKASSKRQSNGSVKNNGKSAPANNEKKIARHMEMIEASASKADQTDLDFVEAQRIEFMKSATKRRRRIQDIDVSFCLRRDQDLALSLGKRLLAHAEFGRKRYDEGNVDAALAEVKEQELHAEKERKKDMQRKRRREKSMAVTIEQREAALARALAAADETERQKHLRDAERASKKAQQTKLILQKGLKGPVRNVDLQQIEGIGNSSILPSETDTPKKSKSRAGNRPKKSREQKQAEKDSAEAAQAAIDAGEELPSREESKARIIRLKSKVSKLDKAEETDKETETKEVKASAKETKEREKAKEKEKTAEPPAPEAKFESKGYNQIYDQIWRDLARKDVGKTFKVAVDSYATKASNLKKTALLASKEAKRWQLRTNKGAKDQQARAKRVMRDMMSFWKRNEREERDHRKAAERQELENQRREEADREAARQKRKLNFLISQTELYSHFIGKKIKTDEVERSTDNPEIAKDTNSSEAPKPSIAVPTAGSSAKVAHFENLDFDNEDETQLQAAAMANAQSAIEEAQKKARDFNNEGPDMDETGEMNFQNPTGLGDVEIEQPKLINAQLKEYQLKGLNWLANLYEQGINGILADEMGLGKTVQSISVMAYLAEKYDVWGPFLVVCPASTLHNWEQEVRKFVPEFKILPYWGTAGDRKVLRKFWDRKHSIYKKDAPFHVCITSYQMVVSDVSYFQKMRWQYMILDEAQAIKSSQSSRWKCLLSFHCRNRLLLTGTPIQNNMQELWALLHFIMPSLFDSHDEFSEWFSKDIESHATSNTKLNEDQLKRLHMILKPFMLRRIKKHVQKELGDKIELDVYCDLTYRQREYYRNLRRQISVMDLIEKATMGDDNDSGTLMNLVMQFRKVCNHPDLFERAETASAFNMGYFAETASFIREGNRIIVPYSPRGAIEYKLPRLVWRNGGRLCKPGSGNVKVGWRNKHLSHMMNIYHPDNVRQSMEGADAFSWLRFADTSVGEVYNATHEGIMDRSVKAANRSDRLEHLGMIYDEEDGDFTPRHALFLIKERSSRRVFADLAPEGALYNMMNAARGWFSMSGLGRLEQAARPSATAIPIDISCTSSATEPERLETLFNISIRRAIYGPNSVEQKAIITEKIRPTFWPTRALLPTPDKEKSRFTNITVPSMRRFVTDSGKLAKLDELLFKLKNEGHRVLLYFQMTRMIDLMEEYLTYRNYKYCRLDGSTKLEDRRDTVHDFQTRPEIFIFLLSTRAGGLGINLTTADTVIFYDSDWNPTIDSQAMDRAHRLGQKKQVTVYRLITRGTIEERIRTRAMQKEEVQRVVIQGGGASVDFSGRRPPEHRNRDIAMWLVDDEQAELIEKRERELLESGEYDKLQKKKGGKRKRAGAAANGDISLDDMYHEGEGRFDDGAASAGGGGGGVVANSDEPAEQPDGKSLKKRKVAGGPKKARSGRQRVAAAVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG32</accession>
    <name>A0ABR3YG32_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Prokaryotic-type class I peptide chain release factors domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_006606</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000333">
        <property type="protein sequence ID" value="KAL1887290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052405">
        <property type="entry name" value="Mito_Transl_Release_Factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46203:SF1">
        <property type="entry name" value="MITOCHONDRIAL TRANSLATION RELEASE FACTOR IN RESCUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46203">
        <property type="entry name" value="PROBABLE PEPTIDE CHAIN RELEASE FACTOR C12ORF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="Release factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Prokaryotic-type class I peptide chain release factors" evidence="6">
        <location>
            <begin position="49"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="39"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="149"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1887290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="211" mass="22945" checksum="BC241997A5584EFE" modified="2025-10-08" version="1">MAAIIGTLASRVTRSSYITPPNVIVRPFSVSTVLFGKHTQLPPRPKPPPESEIEESFLKGSGPGGQKINKTSSAVQLKHIPTGIVVKSQATRSRTQNRNIARELLAQRLDELYKGENSRTNIVAEIKKRKQQSAAKKSRRKYRAFELLKAGANNEMQQSDKERLDAAQDDGAQSVESEESGFDDRIPGSPAVGTAASNPRPSSPVVAKQST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGH1</accession>
    <name>A0ABR3YGH1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_006688</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000352">
        <property type="protein sequence ID" value="KAL1887120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050917">
        <property type="entry name" value="SOX_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45803">
        <property type="entry name" value="SOX100B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45803:SF5">
        <property type="entry name" value="SOX100B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HMG box" evidence="8">
        <location>
            <begin position="160"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="6">
        <location>
            <begin position="160"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="23"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="68"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="100"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1887120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="444" mass="47600" checksum="E335A8C794B5BC60" modified="2025-10-08" version="1">MMHSAEPTSSNSVSGVCPVTAGATYTSQHSKGDSFRAPEDNSTEYPAPSSIASRAMGENIGISWPAVDETQSQSSHREDESRNSSEPVPAIVDRVENAPSHRKRVAKKPARRHSLTIRTPLAQLAAQFPRIQIPDINGFVNRPVEERFRELDTTKNPSEGKRPMNAFLLYRKAYQRLAKTIYGQKNHQYVSQICGDSWKIESRAVRDLFNDLAITERINQHMACRAYTERVSNDIADSEHTSPAMDADGGDSGLDIGELGISFSLHLEGDAALHHNMVPGSAFPSSGESSPLVVVAEGPLFVVSDDNPLFSAPVDSPLFAAFAGSALAGANPGVAVGTWQTGLSMPIINISQPPPLPIPELPLDTSLYLHPLSIELEASFSAYEEGVDPALGPSEQGFFGHATGAFGVGDGVPTSQESMNAGEDWVYYPPAPDTFSMALGLGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGT1</accession>
    <name>A0ABR3YGT1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Inner membrane assembly complex subunit 17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000359">
        <property type="protein sequence ID" value="KAL1887052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="104" mass="12292" checksum="CBB0A94CFD90A554" modified="2025-10-08" version="1">MKFSHSPRVFRPLNLHVPWPAARQILPPRPIRRYSTERPAPSHTDFYKTFGRPIAKVLLIAMFTYQLLYLGWTKLEHNDVKKIRGDEVAKLEEQVKELRGQKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHN6</accession>
    <name>A0ABR3YHN6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006402</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000294">
        <property type="protein sequence ID" value="KAL1887829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389:SF21">
        <property type="entry name" value="ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389">
        <property type="entry name" value="CHROMOSOME TRANSMISSION FIDELITY FACTOR 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="640"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="568"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="575"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="981"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="981" mass="105979" checksum="9A6763936A75568A" modified="2025-10-08" version="1" fragment="single">MSPADSEPSRASTTASTTGKIHPFFKASRPAFERASSPLAHDLSDSSQTGSRKKRKTTSSKDLGPHKRKNTLEGPLLSLLKPQPPVPAEKELNGLETPPALDEEGLEDAEGEIDDENFGFFAGLHPQATARTPSYSPSSTSMQGEPNGLALASCAATDEPGKHSKILKFNMKTGTLGSPPKSKPKKSDFLEVAKPTRGRPRKPPKQLMVTLRYGIDAADRRRISFLIEQILSRPQQPGPASEHATSPALSPYGTTTIAPVSTASAPIVVPNNLTPAQTNRSTHPFFTKGTTTAPSFVTSSTTTASLVATKKSTLSLSTPCSPRRKSQPPASFCGGPSFGIRTKGMKVPGAQYPLFPPQDMVHVRCLDPSSLTLRPESPRRLAPISLPLRKAKQQVTTVPDAESLITCLQSELGIKNITDALSRLSDDFASVPASLRIPKRHVESGRQVQARIRPQIRTPLPGSAPAQPVPIPDDSGSSSDDDLAVVSRFRLQQRQKRQKPEPPHPYIARLYSQLADGLSAYDRCTCESVNWAQKYAPQTTAQVLQSGREALLLKEWLEALKVNAVHTASADPKPKGKGPKKRGKKKNGKLDGFIIDENSDDDDGGAYSPCEDSGDDALAEWAPDVLGTKRSVARTVAGRLRNAIVLSGKHGVGKTATVYAAARELGFEVFEINAASRRAGKDILEKVGDMTRNHLVQRQAGETGEASSTVSKSTAIASFFGKKTADAKDAKDCDSKKDRKDKEPAAQKQSLILIEEADLLYDEDKNFWATLVTLMSQAKRPFVITCNDETLIPLHTLPLHAIFRLRTPPRAASLDALVLIAACEGHVLHRQAIGELWASREGDLRGALAELQFWCQFGVGDVKGGFDWLLARWPMGSDVNEHGETFRVVSEGVYEGGMGWLNRDSIIEGSENPEAAVQCWEDFGIDLYDWRSDANASSVPLQTVDGGKNPLAALEAFSDSADSMSLADVLSMASYAETNQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIK0</accession>
    <name>A0ABR3YIK0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000305">
        <property type="protein sequence ID" value="KAL1887653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="302" mass="33902" checksum="49E489F2C758F104" modified="2025-10-08" version="1">MSSSKSSAQQHQPQQTSPSLSESRMRQSHQSGVNDKDSQHKKKRAASRTRARRQSVSPYSSLSEASDDEDDRHKQSVRHKLRREIARERERMQMKKTVASGSGSSGRSSSKVRHEDTSAGADEAERRSHRHSKQTRFYETPLIFSESDDEDTRQLRINARIAAHNREISRRPSHDSPSSTPSTTHATAIVSSSRAQSPKSSTSSTKASKFKSTPKAAANNYVRPGVEMTVNELVPTELVEYGSGAPGRGSTLSDARRPRSIRQSGYDGMASWQQIQKKMEEEAMHERLKERLVPRYNPSQAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJB1</accession>
    <name>A0ABR3YJB1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Origin recognition complex subunit 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ORC4_1</name>
        <name evidence="7" type="ORF">Cpir12675_006369</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000289">
        <property type="protein sequence ID" value="KAL1887923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15492">
        <property type="entry name" value="PHD_BRPF_JADE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050701">
        <property type="entry name" value="Histone_Mod_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13793:SF107">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13793">
        <property type="entry name" value="PHD FINGER PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="329"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="84"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="187"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="296"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="14"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="114"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="158"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="313"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1887923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="489" mass="53950" checksum="43B6E062618A1576" modified="2025-10-08" version="1">MDQTPTTNRKRGRSSAATATPTSTSKAPPKRRRLNDENKSPIKTESASGLYSFEIDSFGIATKTVPCEQAMSYNMALQAKAPLSSANPLDGQQLVLSPSKPAPAAKRRGRPPKAKAAIQLQPQLQPWPVLQPPQQSVVPLPQIPHHGALPLHLDQQRQKQQQQQQQQQQPSSYSGELQFVNISPQKYTAPASPIKSPLKSPLKGIMTPSRHRGPLTERTRKNVVFDMGGGNKTPSEVVFEDLPGTNSGKRGKPQTPVALPRAAGDDRTPLSEKLRAAAKQAAQKNMAAKDEIESLLAEEEQDEEKSRSPTTFRGHDLEGDRPEEIDEDEEKCQICGQNDSEAPNQILFCDVCDLGYHQQCHGVSTIPEGDWLCLNCAQEDVTKTPSTKRYAKFTGLDVLVSEEPKTTIQEPKFEVPPIPNFEHYLRCFQRVLVDRCTGRRRIKLIGHEEPWEKTHQLIEQTVAAGEGNSMLVIGARGSGKTTVCADYVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJR9</accession>
    <name>A0ABR3YJR9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_006259</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000272">
        <property type="protein sequence ID" value="KAL1888210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="42"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="11"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="74"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="261"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="269"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="519" mass="56121" checksum="929332E7098B7D8C" modified="2025-10-08" version="1">MLHVSGLFPLPARHSHISPLPSPSSSLSTMASPGREVVRHRACDFCRNRKVACSKELGGCMRCTKDNVCCVYSPQKPMGRPRKKPSTNPSHGPRLGPRPGPESRPTVSPTPSASSLPHGSTTPDFSRAAAAADCATALYSVTTTSTTATTIAPSAFTAAPLATASHIASDVSPARHPIDVSSVPHLYHSPNLHAFEEPDIASRNILIGGALEDPSFPHVDDGSNNSSFSRATSAPRSLVSSLHPLGIFSFPDGYDFSTADIGSSHSRNHSQEYAHSHAQDQSQQPPQHSTPPTFSPTLSPPTRIFNSPNPIFLPLSECACQDKMKLSIEILRSLSMASSINPVSAVQTIRDCLDVALGLGCNMCNPSSQLLQSQYFLHSAEANMDVNMALRSAETTSLLCSLVVTLCDTYASLRRLPNLNPNTTDMPPQPTASAPFMQFSNQINCPSSWDWNWDWGWGWDWELEGALREGLHRVLQGLKDREQQQQYSGRASGPEDGGWRQQCPSMIRAAHEALERAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJS5</accession>
    <name>A0ABR3YJS5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">GATA type transcriptional activator of nitrogen-regulated proteins</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SFU1_2</name>
        <name evidence="11" type="ORF">Cpir12675_006127</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000256">
        <property type="protein sequence ID" value="KAL1888563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039355">
        <property type="entry name" value="Transcription_factor_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071:SF335">
        <property type="entry name" value="IRON-SENSING TRANSCRIPTIONAL REPRESSOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071">
        <property type="entry name" value="TRANSCRIPTION FACTOR GATA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00619">
        <property type="entry name" value="GATAZNFINGER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="10">
        <location>
            <begin position="209"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="160"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="169"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1888563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="235" mass="24029" checksum="F7BBCFA5F28B5570" modified="2025-10-08" version="1">MKSKQRKSTSKKRRPLPGFDNTTDENGDIRMQDTPPAQHGTGSNISLGLEPSPPPSKNSASRVSSALPSGQTGQVSRPTKLKKSPANPAPTDVGTSRVKICGASSRQSGAVKGATYVSAEESTGTCPGGGKCNGTGGAEGCGGCPAFNNRVSKTARLNLLKGQGKSDNESGASTSAMSTSPDPKPEGPAPIDVAALEIQSQNSTVVIACQNCSTTITPLWRRDEAGRAICNACGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKN0</accession>
    <name>A0ABR3YKN0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_006069</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000248">
        <property type="protein sequence ID" value="KAL1888719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF10">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="53"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="906" mass="101003" checksum="3643C986A06F2CD7" modified="2025-10-08" version="1">MDIRDLLSRHEKLVHQNVPPKLLSKSRKTSRASNAASKDKERSPTQYHEPFHQQQQPQSQQQQQQQTPQQQQPPSQQQQQQFQAQSSSSVDADTPPVNNQPIQPPLNGSSINLDNRLPPVNFSGYSRGSIHLPPPPFTMANHVSVPTLASNSVISNDANLQMLSDMAASSAPLLPVGEQQSELLPGLDNITPGLHVSFANRARDDDPFSAASFPPAVPSMQMPLEFNLLDEIHLSSAYLAPVFDTTDPITWARVMGSKANSAFPSRAGSPQPDGHDRHPQPQLLSTIDEQHRIPLLRHLTPNDYDLVKARVQDFNTVLPSDFIFPSRHTLIRYLHGYVLGINDNLPILHLPTLHITLMAPELLLAVAAVGAQYRFELHRSYSLWYAAKAVAMEQISRRRSSEVKALLPTSSNYTINSALPSPKMGARHMFSSSNQDRPGLMDGHRETFAPNTPDARLETIQAILLLFAVGLWNAKAVLNESTSLQSTLAMLLREDGLGPDPEIEADCNWETWVRREKAIRTKIIAFCYFNLSSIAYDDPPNILFSELFLSLPQSGKIWRAENEWSWQQARRTEPRVDMTLQDAFAYILGKGTTGEILQVTTLGLYILAHALMQQIWLLKQSAIRGSSKFDASRSLKLDDVDEITSAIRTWEVAFNQRQRVRAAENGTYNFEDSNHPATQIAHNATALVRLAGIKLYTDSHSGKALATRDPNALAKALSNFQVQSRSFQPLARNERMNRAVFHALHSLTLLIKTGVSFVSQSSNSEWSIQHLLCNFESATLLARWLTTIGMTSSQKMPTKDESILVEMIRQVVGETDHAGPIDPSLSTDDTIRKLAAPIDPLDQPTVRRLAQTVLQIWSRTFRAPHIFEVVNVMADALDAYAACLENPSSLFQQMPAPMLRPMDLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKP1</accession>
    <name>A0ABR3YKP1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_006183</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000263">
        <property type="protein sequence ID" value="KAL1888403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="141"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="437" mass="48924" checksum="1C2D78C840948118" modified="2025-10-08" version="1">MSSWFDLGSYFQASTDSSPGASRRQPAGNRPARNSYSTMTTSDSPSKTPEISIEPQPDCSEFATSIDGWPRWLLAARVYALRSAASCAFSCITPFPCEMPQTVSTFYIDSTISRDCAPQAIAVDVWMPTPSPALHSARPALINFHGGGFVIGQGTDDRIWTSYAQQELGAVVFSVNYRLAPGYPFPTPMEDCLDAILQIAARAEEFGISRDQIFLSGFSAGGSLALSSWIVLQDPARWDYHFELPIPSIKGLALFYPGLDWSISREEKRRGCAQPDLTLPASMTDMFDCSYIYPNRPREGRRDLRLSPGLMEDALLKKMPPTHFCLCEHDMLLAEEFRFISRLKAANRDVTHRIVLDEQHAWDKPMPFAPKPSVMEEYTVTINEIRRWIDPSWMDRGYAPMESMETLSHVKSDSISNSSKRMLPFVVERSISSTSSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKS7</accession>
    <name>A0ABR3YKS7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SWIRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000238">
        <property type="protein sequence ID" value="KAL1888936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04433">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SWIRM" evidence="2">
        <location>
            <begin position="401"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="494" mass="53496" checksum="2903827C590B0618" modified="2025-10-08" version="1" fragment="single">STIMSVSPSIPQAEALLQSGIKHTGVQSVPIASVFDISQNVSQTRERHGKAPPATPLVSPPVIHSCMAASSLSDQLSPPPVTDQSFPPYAQNPFMSPASSTVDPATDENLGYQPPLFPVSSPHEELHQLTSDIHACLDRVAKSSYLSQSEVLSSRFGSVQFIGSNFNAMFLNSRPEYTRDRLVEQQRFRKARDIHQKHRQQAKNTNAASKRGASVSLAITSYSRPATWSRPGASPGGPISQDRVKKGGASSMSASTVLARSPVGPPPIGTRSTSRLTVSTNVRPAIQSPSIPLAIHSDGITTSTESGHSAVELKALPSTSPRSRRAITSGATRGVAGSGVFPIENFPRDSGRRGAVASREDKNFWNLADICPPLSTLDGLKEGALKAEWKGNPINLSNDPNLDLLHPLERTLASVLRLDCATYITSKRRLFLSRLDCLERDKIFRKTDAQNACHIDVNKASRLYVAYDQVGWLDAHWVQPFFNKVDLSPVQKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLE8</accession>
    <name>A0ABR3YLE8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_006087</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000251">
        <property type="protein sequence ID" value="KAL1888658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1888658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="123" mass="14194" checksum="F7F232E3BFACD15C" modified="2025-10-08" version="1">MDARNSRAQMRFVIGEIADLEALEAIWDTTLTANIGKTGHAIADWVGAAWERVTGNYIIFREVLSCSWDLLMLTSLMILEERRSGGFFDCKDKWKKENDIILTWDYLRGEWTESLLGGKERMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLL3</accession>
    <name>A0ABR3YLL3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">1,3-beta-glucanosyltransferase</fullName>
            <ecNumber evidence="5">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_005870</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Cell membrane</location>
            <topology evidence="1 5">Lipid-anchor</topology>
            <topology evidence="1 5">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the glycosyl hydrolase 72 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000225">
        <property type="protein sequence ID" value="KAL1889224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004886">
        <property type="entry name" value="Glucanosyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31468">
        <property type="entry name" value="1,3-BETA-GLUCANOSYLTRANSFERASE GAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31468:SF8">
        <property type="entry name" value="1,3-BETA-GLUCANOSYLTRANSFERASE GAS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03198">
        <property type="entry name" value="Glyco_hydro_72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044954368" description="1,3-beta-glucanosyltransferase" evidence="5">
        <location>
            <begin position="19"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="332"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="386" mass="43127" checksum="E6C32AB1D1CB6DB8" modified="2025-10-08" version="1">MTSLKLSLLLGLVTSAAAISTLEQYGNKIYDQEGNQFFMKGIAYQLRPNDPLIDSEQCARDAKLMKELGANTLRVYHVDETADHDGCMKVFEEAGIYLTIDLDDFETYILPYDTFWNETQYDSYAKTMDAFITYDNLLGFYVGNEIIAKSDQSHAAPYIKAAIRDMKAYRDSRGYRKALIGYSATDIVELRPMLQDYLTCGGNNDEIADFFGINAYEWCTPSTYTGSGYDKLQEMAENFPVPIFFSETGCNVGSDREWEDMDAIYSDPMVNDWSGAIAYEWIEEKNNYGIVSYGPPADQDTPITGDIYDGFTRKGTPTPVQPDFDNLKSRWATNTPVGTPRSEYDSSSVSTRECPPATSGGWQVDGNVPLPTLGQTYTGPLPAVQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMU9</accession>
    <name>A0ABR3YMU9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">pectin lyase</fullName>
            <ecNumber evidence="8">4.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Cpir12675_005893</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Eliminative cleavage of (1-&gt;4)-alpha-D-galacturonan methyl ester to give oligosaccharides with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.</text>
            <dbReference type="EC" id="4.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the polysaccharide lyase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.10" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000228">
        <property type="protein sequence ID" value="KAL1889170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002022">
        <property type="entry name" value="Pec_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045032">
        <property type="entry name" value="PEL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683">
        <property type="entry name" value="PECTATE LYASE 18-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683:SF67">
        <property type="entry name" value="PECTIN LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00544">
        <property type="entry name" value="Pectate_lyase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00656">
        <property type="entry name" value="Amb_all"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0964">Secreted</keyword>
    <keyword evidence="2 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045241660" description="pectin lyase" evidence="11">
        <location>
            <begin position="21"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="Pectate lyase" evidence="12">
        <location>
            <begin position="94"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="380"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="400"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="470"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="487"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00036818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1889170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="497" mass="53047" checksum="8827D81F7C31CB61" modified="2025-10-08" version="1">MFFFRAVLCALAAVTSTVHAVGVVGRPQGFAKDTTGGGDLAPISPTDIDELKEWLTDAEPRVILLEKEYNFIGSEGICKDCDCCIPASNTCGSSGQNAIDVINWCKDAPKIKCTYNNVTRIDVASNKTLIGLDDKGVLRGVGLRFSKGASNIIVQNVHITELNPEYIWGGDALSMTDCDNIWIDHVKISLIGRQMISMGFEPSVRVTISNTEFDGRTSWSASCDDHHYWTILGMGTKDHVSFYGNWIHHTSGRGPDLGKCGVWHLFNNYWSDVSGHAFSVFPEPSVFVEGNVFESVKYPDYGTGGTGMFIVNETTAQTCETTLGRPCMENQVSYDSGFLTPQTADNTTTLEIVKKAIDFELKITSPDKVKDSVMANAGIGKLSSGTPAGDGGNNAYNSGSATTAKTTVTSKTTATSKTTATSKTTATSKTTATSKTASAAAGDSYGTPTSVPSAKPAAPKGYKNAQTNGPSFSSKSGQPSSLPKTRCASKRRRLRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN38</accession>
    <name>A0ABR3YN38_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TOG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_005644</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000204">
        <property type="protein sequence ID" value="KAL1889779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048492">
        <property type="entry name" value="Stu2_CTS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045110">
        <property type="entry name" value="XMAP215"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048491">
        <property type="entry name" value="XMAP215_CLASP_TOG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12609">
        <property type="entry name" value="MICROTUBULE ASSOCIATED PROTEIN XMAP215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21042">
        <property type="entry name" value="Stu2_CTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21041">
        <property type="entry name" value="XMAP215_CLASP_TOG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TOG" evidence="6">
        <location>
            <begin position="1"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="6">
        <location>
            <begin position="274"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="500"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="767"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="880"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="923"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="660"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="519"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="556"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="634"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="781"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="814"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="880"/>
            <end position="899"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="969" mass="104623" checksum="5A271A5076A4B4BC" modified="2025-10-08" version="1">MADEESFESIPIVDRFTHKVWKARKSGYEAATKIFEKTPDESDDAFRPFLLDSSLWKAAVTDSNVAAQQEGIIALNAFLKFGGREACVRSRGTVVTGLVEKALASARATTKTNAVEALLLYVEGDVSGPIVENLLPGLSNKQPKIVAATLAAFTAIFHNYGCKIVDPKPVLKGLPKAFGHADKNVRAEATNLAVELYRWLREAMKPMFWGDLKPTQQSDLESQFEKVKSEPAPKQERLLRTQQEALAQAPAGGDDVEAEEEDIVEEAGEVDVFDLAEPQDILKGLPANFYDGVASSKWKERKEAVEALFAVANVPRIKDADFSEINRCLAKCMKDANVAVVTQAAQCIEALAKGLRQGYAKYRPTVMQPIMERLKEKKATVSDALGAALDAVFVTISLTDCMEDIIAFLGNKNPQVKEGTMKFLVRCLRTTRSVPAKPEIQQMVDAAKKLLSESSEALRSGGAEILGTIMKIIGERPMKPHLEGLDDIRKNKITEFFQTAEVKAKDKPKPPPPAPKAAPAPKKVVGGARKAPAKKAAPSAAASRVLSPEPAPPPAAVARPAARAPAKLSGLKATRGRPAAGPSGLSSPRKPAAAPIMPEEEYEEEPAPPPATAPRSIRGGLAGRSLTKPGSAPIMPPESPTTPLYPSPASGFTAIERAELEELRVANERLTRLIDDMKQDRSKLLSENQELKNQNASLIEDHTRDVLSIKAKETQLVRARSDAEATEQTNERLRRELDRLKRALSRAEGLGTSGAVSPVGECLKKRPHDLAFGNTDSETSTTDRDRIASPTHEDAGLYRDAVRTGPGPSAYSRPDSQASRSTANGNRISYASNLSEEKENGEPVYARAKLSPGLGYGSGGSSGLPSGRASPARGYRQTMQMPSSSLHNTQNTDDGSLQGNYGDRIDRHMDRHGSGGHSSMAMDRMSGMNSVDRGGTPTGGVESWKRAAEVTSQLKARIEQMKAKQGFRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNR8</accession>
    <name>A0ABR3YNR8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000212">
        <property type="protein sequence ID" value="KAL1889543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="285"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="357" mass="38319" checksum="A51EC628FEE2147E" modified="2025-10-08" version="1">MEGREFLGEGFKPSMSTSQPEPPLVVGVRQSQSAQSVRAYENYSPNNINTITFELYNDAADCSPDSANSLSPNFYTSERHISPTRSSTNTGSTRSTQRPSSSRSRSPSYAAIPNISGSAATQGLNCVGVGQPSPPVSAISPSAPCSNDDTASTTSSSRRRRNAIDSTNPRVNPFFDPRNLPAVQPATPSLPRSAIIAAQTGPARFRADPRRLEKPPFQQPFNAQHSPSKKRPSYESLHLQLPYGADFSSLTPPFCSESSDSHDDDIVPFPEYDDTAALAALSFSSAFPPSTSSDADPRSLPSISQDTLSALPQPTTRPRSRHNSPASASTPPRRARAGTRDTGSPLRPLSLERPRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPB7</accession>
    <name>A0ABR3YPB7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ATPase AAA-type core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005862</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000224">
        <property type="protein sequence ID" value="KAL1889234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF132">
        <property type="entry name" value="ATP-DEPENDENT ZN PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase AAA-type core" evidence="2">
        <location>
            <begin position="263"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="526" mass="59075" checksum="45839564C72C9339" modified="2025-10-08" version="1">MYPVNRESLLPSSAASAASATMGFPSWLDSVSAEYLKHSSAPRVNTEVQIAQSLRAAYPERYLAIVPSQTCDLLRYADSGWAECSEACRPSLESQQLGLEPANLENLPQMGNTLSHRIKVYVPPSRRMDGATGELRDDVVFDRFDYTWNGRGFKLFIADGRDGSGAYPARRTSYLVGDDQKTTDGLILAAAQFQTEVHNAVLVYEGGEWTRSTALYESAMKASWETVILDEGMRKALIEDHMAFFDSREKYRLLGVPWKRGVIYYGPPGNGKTISIKAMMHSLYDRTPPVPTLYVRNLVTWAGPEAAIKDIFSTARQHAPCYLIFEDLDSLISDSVRSYFLNEIDGLKANDGIFMVGSTNHLDRLDPGLSKRPSRFDRKYLFPNPDTAQREAYCRFWQRKLSANDDIAFPDLLCKAIAEITHGFSYAYMQEVFVAALLAIAREDGDSDDSGSATDGDPDHDETSSSSGVEGDEGWVDIMKDKKHRHHGKHHDKKKGNDDENLDRYILWREVKNQVEILREGMAEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPL5</accession>
    <name>A0ABR3YPL5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_005509</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 3 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000191">
        <property type="protein sequence ID" value="KAL1890193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050720">
        <property type="entry name" value="Engrailed_Homeobox_TFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24341">
        <property type="entry name" value="HOMEOBOX PROTEIN ENGRAILED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24341:SF6">
        <property type="entry name" value="HOMEOBOX PROTEIN INVECTED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 4" id="KW-0371">Homeobox</keyword>
    <keyword evidence="2 3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="6">
        <location>
            <begin position="135"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="3">
        <location>
            <begin position="137"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="212"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="262"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="215"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="262"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="294"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="312"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="368"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="405"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1890193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="666" mass="70702" checksum="0740383D4633C977" modified="2025-10-08" version="1">MEFNNMHGGQQVPMFLPTNQPSLVQQRSPNSYLQSAQAPFLQTPQAQAQAQAQSQAFMQHPTAQNPLFQMSPSDIQFALANSNMASMSLSTGPSHFFNLPAATDAAHQNLMQQSAPMYRHLSEHTYTGAMTHGMPQTAETRPRFTKEEVERLEAMYQQDVKPSTEAKKHMAMELGVAIAKINVSLPLFAMIGRPLETKLLTSNTQNWFQNRRAKAKLEEKAEQSAAEQRRNSSGPSATPSAEPATTEVINEHFADRDAPLRPSAAAFPSIPSSFSSPEASSPTVQQPEASLPKTQTPQVSESQSVSPPLPQMQFQSEGQPFAFSPSTDGNTSIPQSMATESVRDTSVSLAVRRSRLRNSGNGSGGGSSSSISQYSPGSGHDSNRAQMGPRIRVPSAVNARVKKNSVSSASGSSSSSMSSNYTIPQNMMLSVSVDSAPRSLNLTPQLNSPYTPIAPSSNAMIFPSPTSTMPRNSSFSFASGTSTINQKFSPSMPHTPNSEGRMFGSTPVTPSYTDYVISEYLSSLNMPMAYSNNGEYTREMGELRNMATSTGAGTGTGVALNTGNAASSAIVDSAMNSGDMSPNTQNMPTYSAGMGTGVGLGVGTDITSFGTDASISMFAAPSIMQATSAPLSDATAAVGIAEQNVDFAMMNMAMGGANRNMVPFHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPZ2</accession>
    <name>A0ABR3YPZ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bem46 protein, variant</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">bem46</name>
        <name evidence="3" type="ORF">Cpir12675_005447</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000186">
        <property type="protein sequence ID" value="KAL1890371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277">
        <property type="entry name" value="ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277:SF81">
        <property type="entry name" value="PROTEIN ABHD13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="2">
        <location>
            <begin position="101"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="324" mass="36016" checksum="D60D1F180407D722" modified="2025-10-08" version="1">MSSSSSTVTDQTVSFARSVASYLRLPALASTGVAAVFTGLLYFKQKTFIYPSHMPPNARTDVPRPSQFGIKDFEELVIPTNDGEKLSAFFIRAPKNARNSQCTVIMFHGNAGNIGHRIPIARMLINYVGCNVFMLEYRGYGLSTGEPDEAGLNVDAQTALDYLRDRHETSTHRFIIYGQSLGGAVSVKLAAQNQNIGDIAGLILENTFLSMRKLIPSVIPMAKYISVLCHQVWPSDTLIPNITIPILFLSGEQDEIVPPVHMRKLHELARTRKRVWKSFPGGDHNSSVLEEGYFESISTFVNEISDDLPIQGTDEEDKNDFRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQS4</accession>
    <name>A0ABR3YQS4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_005275</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000175">
        <property type="protein sequence ID" value="KAL1890695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF93">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN 25D9-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="245"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="300" mass="32707" checksum="6D289784FADB5702" modified="2025-10-08" version="1">MSMRKEAEEAVVKMADKVVEAVNPANGPLPGTRGKHKIADAVGTALTGGAANAGTRGYLATYFKQLESNPLRTKMFTAGTLAGLQEILASWLAKDRNKHGHYFTSRIPKMAVYGALISAPVGHFMMWLLQRLFRGSVSLRSKVWQILISNTVIAPIQNSVYLVAMALIAGARTLHHVRATVKVGFWKVMKISWLTSPICLAFAQQFLPENLWVPFFNLIAFVIGTYINTTTKKKRLAALRKKHFGDGGRGGSSVVSGGPPPPIRQNMPGDDYAPSHISSHHPSHSHIGPSMHQGPPQPPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQT1</accession>
    <name>A0ABR3YQT1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Peregrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_005264</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000174">
        <property type="protein sequence ID" value="KAL1890706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15670">
        <property type="entry name" value="ePHD_BRPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15492">
        <property type="entry name" value="PHD_BRPF_JADE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019542">
        <property type="entry name" value="Enhancer_polycomb-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034732">
        <property type="entry name" value="EPHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050701">
        <property type="entry name" value="Histone_Mod_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13793:SF107">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13793">
        <property type="entry name" value="PHD FINGER PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10513">
        <property type="entry name" value="EPL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13831">
        <property type="entry name" value="PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13832">
        <property type="entry name" value="zf-HC5HC2H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51805">
        <property type="entry name" value="EPHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="8">
        <location>
            <begin position="389"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="9">
        <location>
            <begin position="443"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="133"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="242"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="349"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="615"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="971"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1004"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1110"/>
            <end position="1213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1242"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1322"/>
            <end position="1395"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1428"/>
            <end position="1455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="376"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="615"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="971"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1004"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1119"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1186"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1322"/>
            <end position="1331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1461" mass="159669" checksum="1A2E8F45138A129B" modified="2025-10-08" version="1">MCEENPPARRPADGVEDHQGAPMQQELQDLQQRRRQQRHPLGLSLALTPFPVMFPSTGVASVATRVARNPRRRRDGIEDSEEFGSAAAVAAAVAQSEGYKPREERGWEEFHPDLELDARFKVFNAAEVDGTVTESPTTVQETIPLPPTTPPKRKVGRPPRDPSAYSGMTAVLGRTPIVLPIHNQTPKERLDLKRPSYRRTDRTSLFESKVPDSDCQISDAVARVGFQQTNQYQRPAHRLIKANDGGWESNNNNNNNNNNNNRNDNISDSNIDEASTGDTDASTGAIPGTSGAGVVVDRSFGRVEYDMDEQDDKWLEAINRERQAADVEPVTRELLEITITKIEKEWHALEKRIPKPNPKPPQTQRPRSSSAAAVNGEAGAGPSSGEEPDSKCAICDDGDCENTNAIVFCDGCDLAVHQECYGVPFIPEGQWLCRKCQLIGRGIPTCIFCPNTDGAFKQTNTSKWAHLLCAMWIPEVSLGNHTFMEPIMEVDKVPKTRWRLSCYICEQRMGACIQCSNKNCFQAFHVTCARRARLFLKMKTSQGVLAVLDGAMTLKAFCDRHCPLDYIEASKVAEATRAARHFYRKKMRGRFWADSESTAALITAQYSVAYDSTESSSESMGASSACGTGTNTKGRSGERRKGIVWKLPSGAPVIPSSVFDAVDTAMARFSLRKRREFVADVCRYWTLKREARRGAALLKRLQLQMETFPSMELTRRNFVSMGPTGEARLQRRIEFADMLVHDLNHLRSLSRTLVQREAIKLRAAKAEKDFVDTCYFPVARDIATIIEKAQSLDSNVFSTGLSALQRRINARFYTTMLTFARDFADVISVGISSEDNALARPIAHGLEAFPTKQKYSDVHARKTLGKHIINSVQPCFETAVITEAAVLQRPADELRKELEEVLRAATEIRVDKPIGQSQGEDSVMPDAPLPGQPVAEDVIMSEAHQDTKETMAKTPLENIAHDAHVLEKSISQTTPPQTTESSLPPSSALGPQDSVDKTVNMLQSTNQNQTPPTPPQSTSNMSFLSDVSAPLPCNVLTDGGPLWYLSDFGVEGLSVVDRYSCDETAHAPSEQLTDLEDDELKGLDRDIERAMGLASSVKIQIPNRPLVKVQATEMGPSESEAKEQPEEKPKERSEGCPPNQNASEKESRGTDVEMVDVIASTEPQPVGPTDGPDATPDSVDDDSAPPRNTVSGSEDTPEPATSTPPTDSAYLPTSPRCAASVAISLEAPQITVTDASLATSIANGCDSAPTSAADPDSQATADPVTTPRHTSPSRTAVHKAPMSSLPLSPCKSAAVPSFLPSLKLHSFESTLPLHPAPQSVFSELSDVSSLPDTDGDADLKDGEGEAEIEAEPAAQDIAQNQTQPSVQDQADAHVEAQDNGEGTVQENANFDPLASTIAPSDNSLDLLLVTSNKDTLPLITRATRANVAAAREAEAQQLELEQRELELERKKRTRSSTRTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSL9</accession>
    <name>A0ABR3YSL9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_005003</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000156">
        <property type="protein sequence ID" value="KAL1891353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043359">
        <property type="entry name" value="GLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45718">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45718:SF4">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="193"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="217"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="392"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="354"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="422"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="450"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="473"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1891353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="482" mass="53676" checksum="37D16AB23882B091" modified="2025-10-08" version="1">MPALQDDTETTTIAASALAHSPDTSLSDDLSDADESDVASRVTDNHSTGVDTTSLRHNRSKRLKTEVVDDAPPPAPASPAIHAHEDEHAPEFLDGMSDVSSDTDGDIPSSPVNTRFDDDDFQEQVSCCAWEGCNAGDQSNMDRLVDHIHNEHIEGRQRKYTCEWTGCSRKSMAHASGYALKAHMRSHTREKPFYCYLPECDRAFTRSDALAKHMRTVHQTEDLRPSDPVPKSHLNGGPNGRKLKIILKTPTSTTGNDESLLDDSLLLDDLEGDHFTQLSEEDFTKEELEMPLEKLFRRCRLQLQWSEEEGEKLLKEIQIMEETYKREWLDKEVLLAQVIQSEKAWYERRKIVLAAEAKAEAEALAAKKLREAQQLENEQKAKAELIKEATARALEKQPDETDADAALPAASDAAKDMAATDERDEDVEVDDAEVEGVEIDPESKMRENMDISEPEADEDKMDLDTPAQDGIKAEPAPAAAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YST1</accession>
    <name>A0ABR3YST1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin-conjugating enzyme E2 11</fullName>
            <ecNumber evidence="3">2.3.2.23</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">UBC11</name>
        <name evidence="3" type="ORF">Cpir12675_004975</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000155">
        <property type="protein sequence ID" value="KAL1891361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23791">
        <property type="entry name" value="UBCc_UBE2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="2">
        <location>
            <begin position="9"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="157" mass="17494" checksum="7CB83A1466C4968B" modified="2025-10-08" version="1">MAASTANASVTKRLQTELMQMMSAPAPGVSAFPTGEGSLMQWNATIEGPDETPYAGLVLRLSMTFPQNYPYAPPNVLFKTPIYHPNFDFSGRICLDILKDKWTAAYNIQTVLLSLQSLLGEPNNASPLNGEAAELWDKDMEDFKRKVLSRHRDIEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT39</accession>
    <name>A0ABR3YT39_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Proteasome regulatory particle subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPN8</name>
        <name evidence="6" type="ORF">Cpir12675_005110</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M67A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000163">
        <property type="protein sequence ID" value="KAL1891102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08062">
        <property type="entry name" value="MPN_RPN7_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024969">
        <property type="entry name" value="EIF3F/CSN6-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033858">
        <property type="entry name" value="MPN_RPN7_8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540:SF7">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13012">
        <property type="entry name" value="MitMem_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MPN" evidence="5">
        <location>
            <begin position="18"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="307"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="307"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="343"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="360" mass="39751" checksum="F67B629676BD1ED9" modified="2025-10-08" version="1">MPATTTTSETLSLASTSVSVAPMVLLSVVDHYNRAVAPGSRKRAVGALLGQNDGTTVRVSNSFAVPFEEDERNPDVWFLDHNFIESMNDMFKKINAREKLIGWYHSGPKLRASDLQINDLFKRYTPNPLLVIVDVQPTASGVPTDAYFAIDEIKDDGTTSRKTFVHTPSTIEAEEAEEIGVEHLLRDIRDVAVGTLSTRLTNQLQSLQGLHYRLRDISAYLKKVVDGELPVNHTILGSLQDVFNLLPNLASPKAGDDTKNAGTSELQHAMSVKSNDQLMAIYLSSLVRAITAFHDLIENKIQNRQQAEEKEAAKLEAEREKQEAAAKDRDGEKKSEGPQMSLDGKDAPPDTNKDGDKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU63</accession>
    <name>A0ABR3YU63_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphatidylglycerol/phosphatidylinositol transfer protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NPC2</name>
        <name evidence="10" type="ORF">Cpir12675_004755</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NPC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000142">
        <property type="protein sequence ID" value="KAL1891924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00917">
        <property type="entry name" value="PG-PI_TP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003172">
        <property type="entry name" value="ML_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033917">
        <property type="entry name" value="ML_PG-PI_TP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039670">
        <property type="entry name" value="NPC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11306">
        <property type="entry name" value="NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11306:SF0">
        <property type="entry name" value="PHOSPHATIDYLGLYCEROL_PHOSPHATIDYLINOSITOL TRANSFER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02221">
        <property type="entry name" value="E1_DerP2_DerF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00737">
        <property type="entry name" value="ML"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046303037" description="Phosphatidylglycerol/phosphatidylinositol transfer protein" evidence="8">
        <location>
            <begin position="21"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="MD-2-related lipid-recognition" evidence="9">
        <location>
            <begin position="45"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="178" mass="18942" checksum="3577524F6DC13C6E" modified="2025-10-08" version="1">MRFLTTAVALLSATIAPASAFSLISQSGAGLVATEKQKIPGDSPLALCDRSHADDVVVIERVDLVPNPPKAGQDLIIKASGIVKEDIYQGAYVLLTVKYGLIRLLTTKADLCEQIQNVDLECPIKAGRLSLTKNVTLPAEIPPGKYTVFADVYTVDKEPVTCLTATVSFSPNMLGAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV72</accession>
    <name>A0ABR3YV72_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Regulator of ime2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RIM9</name>
        <name evidence="8" type="ORF">Cpir12675_004624</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000135">
        <property type="protein sequence ID" value="KAL1892268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051380">
        <property type="entry name" value="pH-response_reg_palI/RIM9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009571">
        <property type="entry name" value="SUR7/Rim9-like_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28013">
        <property type="entry name" value="PROTEIN DCV1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28013:SF3">
        <property type="entry name" value="PROTEIN DCV1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06687">
        <property type="entry name" value="SUR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046659132" evidence="7">
        <location>
            <begin position="26"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="233"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="441"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="473"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="257"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="339"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="354"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="386"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="397"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="473"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="513"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="542"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="574"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="689"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="715"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="743"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="763"/>
            <end position="774"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1892268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="782" mass="83171" checksum="921C45E5BAA0DB0B" modified="2025-10-08" version="1">MLRPATPLSLILVVAFGLLVLSVLSTPVIKGVPLGTFNDFDYGVFGFCHVDDCSGFQVGYKVSTDTTNESDFNLPSNTRNNLTTLLIVHPIACLMALVTMVMAFTSHIRSAAHSSRYLLAVTIMNFLSFLASLLAFLADVLVFIPHLGWGSFVVLGATILLGLSSIMACAMRRTLVSRKSRKKKIAEHAEMSGENFYNRENALKAANAAVAPVPSIPAIPAVPSVNKSTSDGHTAFATFESPKGKANSQVSEERIPLTSQNSIHRMNSADQNNDMPLPPPPINMGGYGGPPRSNSAPPQVDQYGNPIDNGQSMYAGNYNASVDRFNNYSGRGGPQNFRGRGGYGRGGSRGGYNGPKNYPNNDNGYGGPRRGDSSSYGPRGGYGPGPRGPGRPRQPPANYQNDNGYNNCQDTYNMPHNNISMNQGGYNDSYVDTYNTIPNNDGYNNIGNNSNNGNNPNSYVPYSQQQLVIDSYTSDNAQNPTNPMREFNFESENNPGASDLNLPRAESPPPLPADLAATAPPTSGSPAPVAFEMEGSPTEPKASLKSESPREAKVDVEPDGIPQPARLGDGPRQTFVSAASKYSQDGPDGPDNGSVPPSPNNGWGNTARPSALPSPLALGREPSPSKTPENGPPGHGAYYEDVDPRYDNSSISPMPVAPPSHEIMITPPEVTIDDIPGKSDPRSPGCESDVSNFTSISQRGINPRWNPNASPMPPFGGGGPMEGPRGPGHGPGPRPRPRQNLGPGPGQGGPWVGGSSRRPPPAQQRQDMLLNSNPDFALPGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWE3</accession>
    <name>A0ABR3YWE3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Coatomer subunit epsilon</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_004466</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle</location>
            <location evidence="2">COPI-coated vesicle membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the COPE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000127">
        <property type="protein sequence ID" value="KAL1892578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006822">
        <property type="entry name" value="Coatomer_esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10805">
        <property type="entry name" value="COATOMER SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10805:SF0">
        <property type="entry name" value="COATOMER SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04733">
        <property type="entry name" value="Coatomer_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016478">
        <property type="entry name" value="Coatomer_esu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 11" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 11" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR016478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1892578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="294" mass="31765" checksum="FB6155EF3038DC39" modified="2025-10-08" version="1">MDPYSSEGELINMHNAFHQGQYQEVIDFDVSDLSPENEKPARILTLRARLALGQHMAVLDELKGTDDVALQAVASLALNQAGQTDKALSLAERLVESAPEDTTVQTLVGTVLQAAGRSDEALALLGGHQGSLEAVALIVQIHLAQNRNDLALKEVAAARRWAQDSLLVNLAESWVGIRIGGERYQQAFYVYEELAQAPSTSSVRSLVSQAVAELHLGRLEEAQAALEEALTKEPQYAEAIANLLVLNAVASKDVSELATKLKQTHSDHAFLTELEEKSALFDQAATKYSAKVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWI8</accession>
    <name>A0ABR3YWI8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TRIP4/RQT4 C2HC5-type zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004565</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000132">
        <property type="protein sequence ID" value="KAL1892412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039128">
        <property type="entry name" value="TRIP4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009349">
        <property type="entry name" value="TRIP4/RQT4_C2HC5_Znf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12963:SF4">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12963">
        <property type="entry name" value="THYROID RECEPTOR INTERACTING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06221">
        <property type="entry name" value="zf-C2HC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TRIP4/RQT4 C2HC5-type zinc finger" evidence="2">
        <location>
            <begin position="282"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="578" mass="61601" checksum="C72B8B6799EBAE90" modified="2025-10-08" version="1">MSIHQLSRLLPLPDDELKQVLSYAETLSKEASVEHFQNLLGNSPEVSAFISSFNSRRKTSGPSASSSGSTARPQTQSRPQPSQSNAQLRAGGPANILDFEPVPKSASKNKGKKKKADIHVPQARKVDSAGPAPGTAYKKKNQTFEYISSSKKPASGSLGENYSATSVSSGIAPDVLSFMEAISGPSSKGGSSSSTRTPTPAPKTEQPQKKSSKVGGYLIGDGPPKKTKSTLAKPTPIVSTKVKITGGLPMGGASAAVSDLDAAIRALELSTNPTLNPSSKARKCNCVATQHPLQSAAPNCMKCGKVICIKEGLGPCSYCGTPLLQPSEIQAILKELTAERGRERMAVDRDAHKRTELKATPSSYAHARGGIMSDSLLLAHQHRDKLLNFQSENAQRTRIVDEAADFDVGLAQGHLGGSMWSSPLGRAMELKRQQKLLRELEWDAKPEYEKRRQVVSIDLVGGKVVKKMAAVERPATPESDGDDVDDVDDEYGVLDAIGGSGGDSSAVSTGKFSRNPLMGGLIRPVFTPGKGKEAETVRTRVTKWRRVQDDRDDNEAVILDGGIYGHAEPNREEPAVCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWS1</accession>
    <name>A0ABR3YWS1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004373</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000121">
        <property type="protein sequence ID" value="KAL1892839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="110" mass="12812" checksum="1CC4F4E8C2753F61" modified="2025-10-08" version="1">MSPLQNRCNSQTVSGAFYHGQALALRSRQVSVGNADSRRDVSNRFLRGDRVPPWKHMVKIQWLRANLAREKDRRRVESEMDCERRKEERQLHRAEEHLLAGIAKSTDNSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXF2</accession>
    <name>A0ABR3YXF2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Alb1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_004295</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000118">
        <property type="protein sequence ID" value="KAL1893061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053278">
        <property type="entry name" value="Pre-60S_factor_ECM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022784">
        <property type="entry name" value="Ribosome_bgen_Alb1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28280">
        <property type="entry name" value="SHUTTLING PRE-60S FACTOR ECM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28280:SF1">
        <property type="entry name" value="SHUTTLING PRE-60S FACTOR ECM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09135">
        <property type="entry name" value="Alb1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="199" mass="21708" checksum="AF13304AFEDF0349" modified="2025-10-08" version="1">MSKGGIKKKDRAPSERSRVARREFSPSLDAGRAVRALSPAAPEKCDSRPSVLAIHHGAGVSKKTKLGRKAAKSFKQRRRQERGIDRAEAVADITANKISRSIDHNNSVRSRNKTWDEVNKSLGGTKTKSKFGFELLGEEDGENDDIKNDIAPPTTSIFSKAAILGDEVDMDDAGVTIITDSNEPPVPNNVNIKDDDEIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY07</accession>
    <name>A0ABR3YY07_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lea domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004379</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000122">
        <property type="protein sequence ID" value="KAL1892796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.700">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="125" mass="13229" checksum="A4798396C7D193F0" modified="2025-10-08" version="1">MSYRFTQIVSRHALAVSVRPIVIVRPFSMTCPASKTATQSIKDGLRDVGEKIDSAVNTAQSKVKKTIDKAADSSQDLKNKAAKVAGSSKDVADNAVDGAKQVAGAAKNKANQVKADIKTEVERDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYS1</accession>
    <name>A0ABR3YYS1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">WD repeat-containing protein C63.06</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004245</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000116">
        <property type="protein sequence ID" value="KAL1893099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039328">
        <property type="entry name" value="WDR89"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22889">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 89"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22889:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 89"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="337" mass="36471" checksum="EFD07FC987B9C565" modified="2025-10-08" version="1">MYSLQNKASYQFPNSSGDGIYVLDLQRLQNGIVAITSDQRLTAFAPDRLESGPVFSTTTAHENLTNVRILDDEASLVATTGSNGIVSLWDLRDSPHKAEVARFQGGDAAVMSIACDPRTNTVVVGTELQDRTHTASIFVWDIRSTPSESHKYTEVHSDDITELKFHPTDANFILSGSTDGLVNVCDLRITDEDEVVVQTFNHGASIHHADFLTATEVYGLSNDERFALYDMAEQVEKGSAFLDVGDLRKPLGCQYIANVTTKIDGSGAIIGAGSQDQQAFTLVHMAKGPETWALDQSSAVTLPGAHGEELVRGVCFFDESHAVFTGGEDGAIKGWVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ45</accession>
    <name>A0ABR3YZ45_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Actin patches distal protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_004029</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000106">
        <property type="protein sequence ID" value="KAL1893641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009737">
        <property type="entry name" value="Aim32/Apd1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31902">
        <property type="entry name" value="ACTIN PATCHES DISTAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31902:SF14">
        <property type="entry name" value="ACTIN PATCHES DISTAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06999">
        <property type="entry name" value="Suc_Fer-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1893641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="354" mass="38789" checksum="724F15DF0077A276" modified="2025-10-08" version="1">MASKLFSFLSKTSITGKEPKTTWSTLFPTTSPDADGDDCLQDCESCSIKYPKSFSIEKTDTLYGHINAFSTHVVVATGKADWVHNVADEKGSIMQAINNAPKPSNGKLMLSASNMPQPSGTTDYSEPTRVLLLPAFVYLDQVTPANVPTMITSYIDVAPTSTSELVPFELPEAAGADPPADVSQDTKKLTPPQIIASQCPHSVVILMCSQKTRDARCGQSAPLLKKELERHLRPLGLYRDYDDTRPGGVGIHFISHVGGHKYSANMMIYRRPNAFGVDNVERSKLPDGEVLKPKETERKPLGEDVGAAQCMWLARVFPQDCENIVKYTVLQGKLVKPESQLRGGYDRANGLLSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ55</accession>
    <name>A0ABR3YZ55_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003978</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000104">
        <property type="protein sequence ID" value="KAL1893680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045557555" evidence="1">
        <location>
            <begin position="20"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="316" mass="34092" checksum="3E43F622810313F3" modified="2025-10-08" version="1">MARSYTLSLLLGLASLAVAQCPAEPNKLVCYDYPGAVTQDLDIIDVQTISWYLRWYSHTEGNPLFWTMYTTDNETTTSVPLNDTSLASLTPGSNSTTPNNSTLAGGISIYSSSNVIGNGATLNNSTIANSNITTAQNDNSGSLNSTAPYLNLTTPTALPSSSRPNVVHTFSTMSHTAAPTVVSQPPVAADQCLEWTVITRGTVMLLARLSGTRNASVLYDDIAYSLDGITGDWGKWIPRGRGTEDEQKVPVLIDCNNSGGQVPVYVNKTNPAYHSEEFLEKNYSTEGIWLKLVHTPPAMEMGKRSTEYGEPVLGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1H3</accession>
    <name>A0ABR3Z1H3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">S-adenosylmethionine synthase</fullName>
            <ecNumber evidence="10">2.5.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">SAM2</name>
        <name evidence="15" type="ORF">Cpir12675_003779</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the formation of S-adenosylmethionine from methionine and ATP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17 10">
            <text>L-methionine + ATP + H2O = S-adenosyl-L-methionine + phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21080"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.5.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="10">Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the AdoMet synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.6" evidence="10"/>
    <dbReference type="EMBL" id="JAWDJO010000095">
        <property type="protein sequence ID" value="KAL1894137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004478">
        <property type="term" value="F:methionine adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18079">
        <property type="entry name" value="S-AdoMet_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00086">
        <property type="entry name" value="S_AdoMet_synth1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022631">
        <property type="entry name" value="ADOMET_SYNTHASE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022630">
        <property type="entry name" value="S-AdoMet_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022629">
        <property type="entry name" value="S-AdoMet_synt_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022628">
        <property type="entry name" value="S-AdoMet_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002133">
        <property type="entry name" value="S-AdoMet_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022636">
        <property type="entry name" value="S-AdoMet_synthetase_sfam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01034">
        <property type="entry name" value="metK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11964">
        <property type="entry name" value="S-ADENOSYLMETHIONINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02773">
        <property type="entry name" value="S-AdoMet_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02772">
        <property type="entry name" value="S-AdoMet_synt_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00438">
        <property type="entry name" value="S-AdoMet_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000497">
        <property type="entry name" value="MAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55973">
        <property type="entry name" value="S-adenosylmethionine synthetase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00376">
        <property type="entry name" value="ADOMET_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00377">
        <property type="entry name" value="ADOMET_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 10" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="9 10" id="KW-0630">Potassium</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S-adenosylmethionine synthetase N-terminal" evidence="12">
        <location>
            <begin position="5"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="S-adenosylmethionine synthetase central" evidence="13">
        <location>
            <begin position="117"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="S-adenosylmethionine synthetase C-terminal" evidence="14">
        <location>
            <begin position="239"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1894137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="383" mass="41666" checksum="06028F7BEF279CBB" modified="2025-10-08" version="1">MSGTFLFTSESVGEGHPDKIADQVSDAILDACLAEDPLSKVACETATKTGMIMVFGEISTKAKLDYQKVVRDTIRDIGYDDSSKGFDYKTCNLLVAIEQQSPDIAQGLHLDDALEKLGAGDQGIMFGYATDETPELFPLTLQLAHKLNAAMSTARRDGSLPWLRPDTKTQVTVGYKYDNGAVVPQRVHTVVVSAQHSPDITTEELRKEILEKIIKKTIPAKYLDDNTIYHIQPSGLFIIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDFSKVDRSAAYVGRWIAKSLVAAGLARRALVQLSYAIGVAEPLSIHVDTYGTSQKSSDELVKIIRDNFDLRPGVIVKELDLAKPIYLQTAKNGHFGTNQSFSWEKPKALKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1J3</accession>
    <name>A0ABR3Z1J3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPS21</name>
        <name evidence="5" type="ORF">Cpir12675_003851</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Has a physiological role leading to 18S rRNA stability.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the small ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000098">
        <property type="protein sequence ID" value="KAL1894067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1230.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001931">
        <property type="entry name" value="Ribosomal_eS21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018279">
        <property type="entry name" value="Ribosomal_eS21_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038579">
        <property type="entry name" value="Ribosomal_eS21_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10442">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01249">
        <property type="entry name" value="Ribosomal_S21e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002148">
        <property type="entry name" value="Ribosomal_S21e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00996">
        <property type="entry name" value="RIBOSOMAL_S21E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR002148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1894067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="87" mass="9681" checksum="BB0FACB08204E399" modified="2025-10-08" version="1">MENDKGEIVDLYVPRKCSATNRIIKAKDHASVQISIAKVDESGRAVQGENHVYAMCGFIRALGEADDSLNRLAQRDGLLKNVWNPIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1X7</accession>
    <name>A0ABR3Z1X7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcriptional activator HAP2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">HAP2</name>
        <name evidence="8" type="ORF">Cpir12675_003575</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NFYA/HAP2 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000087">
        <property type="protein sequence ID" value="KAL1894636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001289">
        <property type="entry name" value="NFYA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12632">
        <property type="entry name" value="TRANSCRIPTION FACTOR NF-Y ALPHA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02045">
        <property type="entry name" value="CBFB_NFYA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00616">
        <property type="entry name" value="CCAATSUBUNTB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00521">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51152">
        <property type="entry name" value="NFYA_HAP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="46"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="159"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="52"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1894636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="232" mass="24879" checksum="B3DA3B05E65CFFB1" modified="2025-10-08" version="1">MYSSSQYGVPQQAMHYGMPPIQAAAMAATAAASGANTNGFEYLANTNITQRSPKDKRDPRSPENRRLSQVSSPTTTVTTAAMLNHASRAAGAVTNPVTATAPPMETVEPTVAPAEESPLYVNAKQFHRILKRRVARQRLEEQLRLTNKGRKPYLHESRHNHAMRRPRGPGGRFLTADEVAALEKGKNGELSADSFGDGLSSKAQGSASGTKRKASESPTSAAKKVKAEGLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1X8</accession>
    <name>A0ABR3Z1X8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003588</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000088">
        <property type="protein sequence ID" value="KAL1894601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF54">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="504" mass="55634" checksum="F8CBDF289108F362" modified="2025-10-08" version="1">MSEEPTLPPLPPIDKNDLYTQTPVCNPRKRALQRSGCYPPSFATSSDPAIFSSDDDPSLENYEPSSERRKRRLVGSWYEHNVAAPSSSDSTTDDTVLQKPMRPVTRRIFTNNFDSGIYLGSDGMTTDDDSLSMPPPPPPRRSRRLTMGLGCQLSEEQRQARRIVERCVQDSDEMIDLSLLSLESLDNDSLAPLNNLTYIPTVVDGAPFEPREPRIKILLSNNCLQSMPGALIDIGNITYLSLRANNLSELPPSIGKMKNLEILNVASNNLRYLPSSLLKLLGPSGKLKDLLLHPNPLIQPETLFTRSLLDMDKAQEKCIGVAAFYLDRSATQFLSTSGHICSQTTIPLLPTAATIPCNGEALDAATPFDAGPGSNVASLVELVLRQCYNSSHLRELPKYVEGHEFQGIRKLLESTQEVYNLRGNTCASCEKLLVKPATQWIEWWAIARLQVSDTVSQTGSVEANKPIISLIDENGSISVPFFAEGCTWKCRPRPIPQSTSFATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z296</accession>
    <name>A0ABR3Z296_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000093">
        <property type="protein sequence ID" value="KAL1894307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="504" mass="56312" checksum="45C6F4521B8F1C8C" modified="2025-10-08" version="1">MVSTAQSNLASAEGLMQSVHPPSSHTGSRIGSQSQDVLGSHSKPAYIRPCLNVPEYSDEGSLESQVKSTGSLPWKHPGAQERNYSIKPQPVLKMVTDLPPARLVVPSPDAPPHLRPPKLPYNPYKRDPTALSPLRISPHGQMPSDPWLTESLPPRLYDTPIDWNMVRQASMQRSLINPFAEPRRRRVTREMLQLHIPPETWYGAGLACSMAGHPESDVSTSAWSPSMLVSSMGAALHALRSPIRNAWSPVYTREELLRQQEEQAPPTFLRDDNCTRPVYPSLDRVEVGMHVRKSAPLSYSIPRKLQEATADAHFKIEPNSSTVSSPPQPQPPSQLPAGYNSILGQHASTKHTPAHLVNDSDTMLYGSRFNPSYKRCYSSRTPTRTLRAATTAKSINCTVSTPESSCQITFHTVKRAAMFMRADRRNDAHEAMETIRQWLEQRQVQDFLIAVGVWATVVVLLKWLDVSPPTTARIAPTRAEVFKDWGFSYVRVSEERLWSVGEQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2Q5</accession>
    <name>A0ABR3Z2Q5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003656</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000090">
        <property type="protein sequence ID" value="KAL1894479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="276"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="509"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="578"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="76"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="286"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="296"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="509"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="585"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="613" mass="66744" checksum="7BCC3BE0B7DBE9BF" modified="2025-10-08" version="1">MAAFSTPCPPPFVFPLAPHLQPSESKSETPSQIQLRLPTQSSSSLAYTTMSAVISASNMSLYAALRHMEAQNQAVREAWESERKYLEANRARAEEVYMEERSIMDEAVNLMETERDQLLEEIYKLRNNVRHLESENGVLRQRLGLDSSISLLMDETNHPVGLRGGADSSDSIFLSPLKPATDDAGLVLQSQLQPQPQLRTTSTLLSPAPVQGPVAPMDFLATKRSSVPTIDIHEIHPELEGIPIKATAIKSPTFTDIEPAPLPAETCIKPLMLETPVEDGSHTDPDLDGDQDVDTEASTLKSPSSDRMLAHHGGGVPPEDTLQMLAVHESVRLKIHAGHTPNHSLSKFPSFTAATCSTTGANTVNGPTPNHCYETPAALGNPTVFDVSHTYQPRVDACEEKYEEGKQNLLLDQQSGPSCCPQFPVSQITQTDSYFSGDNSKAINNASQDPVLAATRRTIADAEDFEGTLMPPKHDQPLTGPLMITNIPAKDEIFLAKLSEKLEAVKISREASPESLTHSENDDQSQFAPPPLPLPVAEAEKDAAIEENTEADAELESKIPKLDKWECGAGGREISKRPRAMAGLVDEDGDDEPDIPLRFKKTTNFGLPMGQSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2W3</accession>
    <name>A0ABR3Z2W3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Gamma-glutamylcyclotransferase AIG2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003922</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000101">
        <property type="protein sequence ID" value="KAL1893854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06661">
        <property type="entry name" value="GGCT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.10">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009288">
        <property type="entry name" value="AIG2-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013024">
        <property type="entry name" value="GGCT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06094">
        <property type="entry name" value="GGACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma-glutamylcyclotransferase AIG2-like" evidence="1">
        <location>
            <begin position="73"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="271" mass="29252" checksum="45867C6B83F5C193" modified="2025-10-08" version="1">MSPFVVSKPTNGNPDSGQAKARAITAKANNNLPSTLYRPLANLTIGSRLAPPPQDPITLADVRRLWPTSPIPVFIYGSLRDPDVLQMASGISQPPELRPALIRGFESMMWTVFPSAIACEQKSAHAGGKSSDSVIYGSCFDASCHSFIAKLSAYEGPMYSLSLCTIELLQGTDSTDVLSQSTAKGRSDRDQKQSPHKSLVRGLIFVAAHNTPVNKGTFDLTRWQQISKQATLMRLVNELAASPPAHLTIPTANGNLNNSPSQRFPIQIAQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z333</accession>
    <name>A0ABR3Z333_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000088">
        <property type="protein sequence ID" value="KAL1894597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035426">
        <property type="entry name" value="Gemin2/Brr1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04938">
        <property type="entry name" value="SIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="547" mass="60837" checksum="AF8536C0C63DD871" modified="2025-10-08" version="1">MAAKRPHDGYLDCPAPDLLASDGTLDKSIAAPSSKRLRKSNTAGSKARQHQNAFIDSTFGQKYFFAGQGTPTSVPKDDELDFEDDSAAMAYLTSVRNQASGIPHLLVAPKIKIGPQLPAGLVGGDANDRIEAQYCPENNNDYEHGDHCHRDEEYGGYYEDGAYTAAPKAVLVEDQHVEINPKQVLSDVYYSSILDRFHALREVLHRPPPEHLVEALPKTHGHFVGTFGPRSSTFIIWNKRLLDFDPHPAQLASMEKDGVLRILRVIMGGKFLRRGHEVRERTARWIWALLARLPDAGQMQHTEIAWIRDLGRRAVLMTRSLIEMAALRDELASSTAFRVDLDVDLNTDLRIQSPVSESDADLNPLVEMKVNDSDEVLIHNATTDERPYSGRSNSHTSPGKDSTGHLCPASSPSSTAIPQLSELDGESMDMSDEEGQVVEDSQARTVTLEAAKSRLLARISAIEHSDEMDYVKEPEILDHMTISPLVDAEGVCIYETNRNDADDALAIEKEQRARINMRHTLNMILTVVGEIYGQRDLLEFRDPFPSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z402</accession>
    <name>A0ABR3Z402_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial phosphate carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">MIR1</name>
        <name evidence="12" type="ORF">Cpir12675_003225</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000073">
        <property type="protein sequence ID" value="KAL1895366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044677">
        <property type="entry name" value="SLC25A3/Pic2/Mir1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45671:SF12">
        <property type="entry name" value="MITOCHONDRIAL PHOSPHATE CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45671">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25 (MITOCHONDRIAL CARRIER PHOSPHATE CARRIER), MEMBER 3, LIKE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="12"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="110"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="208"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1895366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="304" mass="32124" checksum="1ECC4FEE3286D73C" modified="2025-10-08" version="1">MTATTEKPTGLALYSRFALAGAICCSITHGALTPVDVVKTRIQLDPATYNKGLVGGFRQIIQKDGAGALLTGVGPTFAGYFMQGAFKFGGYELFKQKWIDFLGYETAVQNRGAIYIASSASAEFFADIALCPLEATRIRLVSEPTYASGLVSGFTKIVKNEGFGALYAGFGPILLKQVPYTVAKFVVYEKVSEAAFRKFPKENLSDGLQTLVNLGSGLVAGFAAAIISQPADTMLSKINKTKGAPGEGTTTRLIKIGKELGIKGSFTGIGARLFMVGTLTAFQFAIYGDVKKALGATSGVEISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4M6</accession>
    <name>A0ABR3Z4M6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Prohibitin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PHB2</name>
        <name evidence="8" type="ORF">Cpir12675_003683</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the prohibitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000091">
        <property type="protein sequence ID" value="KAL1894454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03401">
        <property type="entry name" value="SPFH_prohibitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000163">
        <property type="entry name" value="Prohibitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222">
        <property type="entry name" value="PROHIBITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222:SF1">
        <property type="entry name" value="PROHIBITIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00679">
        <property type="entry name" value="PROHIBITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="Band 7" evidence="7">
        <location>
            <begin position="53"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1894454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="301" mass="33349" checksum="8702A1F7356922E3" modified="2025-10-08" version="1">MDRNPMEQYMRKLREMAQSQNIRRGSPRGTPPGAGLIAGSLLAFAGSYMFYNALFNVDGGHRAIKYTRLGGVSKQIHGEGTHVMIPWFETPIVFDVRAKPRNVASLTGTKDLQMVNITCRVLSRPEVAALPQIYRTLGVDYDERVLPSIVNEVLKSVVAQFNASQLITQREMVARLVRENLAKRAARFNISVDDVSLTHLAFSPEFTAAVEAKQIAQQEAQRAAFVVDKARQEKQAMVVKAQGEARSAELIGEAIKKNKAYLELKKIENARAIAVLIQESGGRNKLLLDADGLGLNVFEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z505</accession>
    <name>A0ABR3Z505_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit C</fullName>
            <shortName evidence="4">eIF3c</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 93 kDa subunit homolog</fullName>
            <shortName evidence="4">eIF3 p93</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Translation initiation factor eIF3, p93 subunit homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 8" type="primary">NIP1</name>
        <name evidence="8" type="ORF">Cpir12675_003276</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000075">
        <property type="protein sequence ID" value="KAL1895319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03002">
        <property type="entry name" value="eIF3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027516">
        <property type="entry name" value="EIF3C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008905">
        <property type="entry name" value="EIF3C_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058999">
        <property type="entry name" value="EIF3CL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13937">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITATION FACTOR 3, SUBUNIT 8 EIF3S8 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13937:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05470">
        <property type="entry name" value="eIF-3c_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26569">
        <property type="entry name" value="EIF3CL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="7">
        <location>
            <begin position="611"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="807"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="171"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="828"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="847"/>
            <end position="857"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="870" mass="97739" checksum="137D495265099082" modified="2025-10-08" version="1">MSRFYHGNDDSSSDSSSDEEELYSEEEEQQLKDSSDEETDSMDDSDDSDDSDSSSEDEGGKKTGAAKFLVGDDSDSDDSDREVRSKVRSAKDKRFEELESITKVIENASKIGDWSTIAAEYEKLNRQVAKLVIGGKAPRVYIQASADLEDAMNDAVAKQKVTPKKMNATNARGLNAVKQKIKKNNKEYQSQIDAYRSDPDKFMSGADDVEEAQKPQSKKIARVAVDIRESTQDIDEGEDDGFAQVGKGGKTVQYTPESIFKHLRTIMESRGKKNTDRSDQIKTMEKLLDIAVTPYQKIRTLLTLVSTRFDLGAGNATMPLEQWKAAEQNMSTLLNVLFANPEWIIIENAEEWEDDEKPPALGENDKYIKVPGSIVSYVERLDDEFTRSLQNIDPHTPEYIERLQDEGSLYTVIFRGILYYEFLRKVTDVEIPQESINRIVMRRLEHVYFKPEAVIKVFEENFWKSVSTDVDSAITPRATTVDANSLVTVLCGYLFSNSEGILRARAMLCEVYFLALHDKYYQARDMSLMSHLQESIPNFDIQTQILYNRTLVQIGLCAFRKGLIYDAQNTLQEICGSGRQKELLAQGVMMQRYGQVSPEQERLEKQRQLPFHMHINLELLECVYLTCSMLLEIPLLAQTGSSPDIKKRVISKTYRRMLEYHERQIFTGPPENTRDHVMQASKSLAAGEWKNAVTYIHSIKIWDLMPNCEEIKTMLAKQIQEEGLRTFLFTYAPYYDTLAIEMLSAMFELTAVKVAAVVSKMISHEELSASLDQATSTIIFRKGVELSRLQGLSLALSDKASALIESNERTLEQRTAGSSAAFDRQGGRGRGGARGGQRTGRGGARAGGHTQRQAGGTQFTGGALGAVVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z545</accession>
    <name>A0ABR3Z545_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Maintenance of mitochondrial morphology protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">MMM1</name>
        <name evidence="11" type="ORF">Cpir12675_003141</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer. Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endoplasmic reticulum membrane</location>
            <topology evidence="8">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <text evidence="8">The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the MMM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000069">
        <property type="protein sequence ID" value="KAL1895750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21671">
        <property type="entry name" value="SMP_Mmm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03103">
        <property type="entry name" value="Mmm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027537">
        <property type="entry name" value="Mmm1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019411">
        <property type="entry name" value="MMM1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13466:SF0">
        <property type="entry name" value="SMP-LTD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13466">
        <property type="entry name" value="TEX2 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10296">
        <property type="entry name" value="MMM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="6" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="topological domain" description="Lumenal" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="8">
        <location>
            <begin position="44"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="10">
        <location>
            <begin position="118"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="334"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="75"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="372"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1895750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="416" mass="46573" checksum="23BE583A23E3273D" modified="2025-10-08" version="1">MALPLDEAPVARPEPTLSFTQGLIVGQLSVVIVLAAFIRFFIFGDAPSAEETAAQRATERRSRTLAHKNSLLRLRSSNRGHSSQPTLNRKKSSVLRGPPTLTIGSILSKTYYKVDSHQPESLDWFNVLVAQMIAQLRSDAQHDDAILDSLTKALNGDSRPDFLDEIRVTELSLGEDFPIFSNCRIIPVDEDGIVMANAKSLNASVASRDGPRLQARLDIDLSDMLTLALETKILINYPKKLSAVLPVALAVSVTRFSGTLSISFIPNNRAQQTPAMMAFNFLDDYRLDLSIRSFLGGRSRLQDVPKIAQLIESRLHRWFDERCVEPRFQEIPLPNMWPRKKNTRGPEDTHSESSNAASGIIVSRVNSTTRSKSRDIPKEVQEEARKEVEAEIDARSSDLSQDRDTLRMRRRRGVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6C9</accession>
    <name>A0ABR3Z6C9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA ligase</fullName>
            <ecNumber evidence="7">6.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_003039</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP + diphosphate.</text>
            <dbReference type="EC" id="6.5.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the ATP-dependent DNA ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.1" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000066">
        <property type="protein sequence ID" value="KAL1895817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07900">
        <property type="entry name" value="Adenylation_DNA_ligase_I_Euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07969">
        <property type="entry name" value="OBF_DNA_ligase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3260.10">
        <property type="entry name" value="DNA ligase, ATP-dependent, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050191">
        <property type="entry name" value="ATP-dep_DNA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000977">
        <property type="entry name" value="DNA_ligase_ATP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012309">
        <property type="entry name" value="DNA_ligase_ATP-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016059">
        <property type="entry name" value="DNA_ligase_ATP-dep_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012308">
        <property type="entry name" value="DNA_ligase_ATP-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036599">
        <property type="entry name" value="DNA_ligase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00574">
        <property type="entry name" value="dnl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45674">
        <property type="entry name" value="DNA LIGASE 1/3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45674:SF9">
        <property type="entry name" value="DNA LIGASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04679">
        <property type="entry name" value="DNA_ligase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04675">
        <property type="entry name" value="DNA_ligase_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117018">
        <property type="entry name" value="ATP-dependent DNA ligase DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00697">
        <property type="entry name" value="DNA_LIGASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-dependent DNA ligase family profile" evidence="10">
        <location>
            <begin position="529"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="28"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1895817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="855" mass="94870" checksum="0C35B08B7527A316" modified="2025-10-08" version="1">MASPSKKRKLNSGLSAHGLEYFFAKQQRTKDAGTTSKADVNGTSHHYDSSSALATDEELARRLQAEFDLEAQAQLNQTDSRDTAKIDVTETSDLANPDSVVDESIPITVARDSTFTKTLALQSTSTADDKLSESLPLDQSPFVFEPCQYLPALKDQWKSQSGNASYAVLIRCFVLINSTASRIKIVDTLVNCLRLLIEGDPTSLLPAVWLATNAISSPYESLELGLGSSSISRALKKVCGLDNRALKALFNRHGDAGDIAFEAKKKQTFTLRKREPLTIQDVYSSLVKIAQAKGQGSGEIKQSIVNRLLQNARGGEESRYLVRTLCQHLRIGAVKATMLIALSRAFVISKPLDKEFPIRSTESLLKLKKEELAKIWIRGEQLVKGCFARRPNYADIIPLLLEVGVSDELALRCGLSLHTPLRPMLASITRDLSEMLNNLHGRDFTCEFKYDGQRAQIHCDEQGKISLFSRHLELMTDKYPDLVALIHKIRGEGVSSFIMEGEVVAVDPESGDLMNFQTLSGRARKDVDIGSVKIQICLFAFDLMYLNGRSLLDSQLRDRRDLLRSSFVEIPGQFTWAKSIDATSQDSEAVLNFYQSAIRSKCEGIMVKILDNAIDSKSLDGPHVSFSTERSTAKALSIRGGKSGEGEVITKPGGYRKTLLATYEPDKRLESWLKVKKDYNASFDTLDLIPVAAWHGSGRKSKWWSPILMAVRNEETGSLEAVCKCMSGFTDVFYKANRAFYSDGTSEGEAQNTRESQPAFVEYTGPSPDIWFEPQEVWEMGFADITLSPTYSAGIELVNDGRGLSLRFPRFIKKREDKSIEEASTNEFLAELYRKQEAAGPKLAQEAIGEGVEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6W3</accession>
    <name>A0ABR3Z6W3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">37S ribosomal protein YMR-31, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_002973</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the alpha-ketoglutarate dehydrogenase component 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000064">
        <property type="protein sequence ID" value="KAL1895997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020373">
        <property type="entry name" value="Kgd4/YMR-31"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10937">
        <property type="entry name" value="Kgd4-YMR31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="36"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="54"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00043970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="126" mass="13433" checksum="DEF3ADB666F47F7B" modified="2025-10-08" version="1">MNSTAIRRAASAAAERTPLIKFLGKRVYPPASQIDHAPVAHPMSPNGVLPARHNSFTTYRSSAQQHGPLHNSPRSGNSVPGSRLGPIAPPIGVFFDRSELPPAYHYTRIDLTEIDAIESGGASLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7J5</accession>
    <name>A0ABR3Z7J5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002896</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000061">
        <property type="protein sequence ID" value="KAL1896249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1896249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="317" mass="33871" checksum="725C10DA9D0763A6" modified="2025-10-08" version="1">MHPTPPSALLSSPFPILNLPLDIILTIASDHLSSVSALCLALTCKPLYHSLFVYSCRNLTSHADKVAFLTLLEIAVPNSVLCFACSKLHTCSFPYQPVGVPASPLELGWDCRHAYSWMPAGLGAVVGLSFRDARQAALRAARAQMEIGMNGVPIPDLDVHSEQMAGGLAVGLSRQVAVIQNSLMAHCTYTFYIAGRSIAEVAAAVEAASVGLCQHVDLDSGAVHAAAEVADTEGLSQHAVKCCSECAMDYSVRFSGRNEKTSMEVLAWHTFGSCKTPFEKAWKNATIRRRRLLGGGDDEPEAGLARAAWSTASIQQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7L6</accession>
    <name>A0ABR3Z7L6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Vacuolar protein sorting-associated protein 51 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003035</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the Golgi-associated retrograde protein (GARP) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
            <location evidence="2">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the VPS51 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000066">
        <property type="protein sequence ID" value="KAL1895813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014812">
        <property type="entry name" value="Vps51"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15954">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 51 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15954:SF4">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 51 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08700">
        <property type="entry name" value="VPS51_Exo84_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="2" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="50"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU368010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1895813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="295" mass="32280" checksum="A365A1A71130B6BF" modified="2025-10-08" version="1">MSTIASPRDSSLSLSARRLPGTPTLTSPVGSSRPSIDTPRSSANSPVLPPAGLAPAGTAPLTTSKRKNRAALREYYNLQRGPSPVSSVQPDPDGLQSEVDFGELDAPKFDSAAYVRKVSEELGLEELLKVYTKILGETRALDAEKKALVYDNYNKLIAATETIRKMRANMDPLNPIASTLDPKMAQIYEQASVIRQSLQESVPEPSSETDHSRRMRQIASDVLNVPARLRYLVGKHDVEAAEKEWKLPRKLLLDWKEKGIGGEEVCKLLEEGDRIIREAATEGSRGEGDDSASEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7X7</accession>
    <name>A0ABR3Z7X7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_002710</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000055">
        <property type="protein sequence ID" value="KAL1896688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044613">
        <property type="entry name" value="Nep1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46468">
        <property type="entry name" value="SENTRIN-SPECIFIC PROTEASE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46468:SF1">
        <property type="entry name" value="SENTRIN-SPECIFIC PROTEASE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="6">
        <location>
            <begin position="366"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="199"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="579" mass="63861" checksum="E17699C63951FC18" modified="2025-10-08" version="1">MLLNDMRTSRQTSLKLVSIEEAEACAQRTNTIDAHLIQLEELLQEANTSKLPGSLEHISNSRQLAEQVTHVRGVMRRIYHTLPLFLRQQQAGGELTGTLVSQDERPLLDMVAAFLLGLPEVSRRFGLILSPYDKETVMNVGGDVRDLLDGKFPASFVKPEALASEESGEFVPAIPELHGAADSLQLRHSWNFAYRRNTSSSGNSSSSNGGDDSADERITVYSIDDEDHEHSATNVENDSDCLVPDSQLLKCADFLPQKTLSILCPDETEDEDDETQKDFSNLTLYLSTSARDQITAAQEQLEREEAAKRVRVDRALRASGTLREARRPLFPEAAARKISKSIIEAMRSKLPTQIAQVFPVKAPDGTQLHPHDFGTLVKSQAWLNDAIIDSTLAAIDRFANLHSGATNYPRSSDRTVLVLGSFFFPNLVKNGGKRTERSLRLKGVTPENFLNLETVVIPVCQGSHWTLLVVQPLAKKFTHMDSLNPRGSPSMLATVQAWLRHVLGAAYVDTEWKKVNIPAPVQNNGYDCGVFTILNAISVVLGLQPTSVYEAVDMPEHRWHIAAMLVNGGFGGDFDVGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7Z4</accession>
    <name>A0ABR3Z7Z4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000054">
        <property type="protein sequence ID" value="KAL1896703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="520"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="610"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="520"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="532"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="542"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="560"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="610"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="686" mass="74354" checksum="CD4ED791F4775829" modified="2025-10-08" version="1">MQPISDPVSPRVRPIHPLPKRRLRERLSDEVAESIEYPPSSPATPTPIFHYPAYNPELGYVLKSELFPSGSGSGSGSGSGSPSAHSPSPDPRLRNHPGFRANGAPGNTNANFASNTFAAGSRHTLNRHGSKGKARRYSHPLELSIIAATLPTPKSQPPKTKLNQSTFSSSFENGNNKKRKIPIMTEPPVFSNNSSIALSIPTGTRSAPNAAGSSSRGETYDSTDPSMSSSGPKDRPGLSHSLNYVSTPPPNSVLTTPTSTKGGISGPGRGMFGRPKNPRTPLRAAVNPSPHAWPDHRTTGIGPVPASAMGGPSSSERMRSVPAWTTTDTHPGGIISNAIAMAEKMSVTTGNDNVSLLAQHTESKTTPTETQFTFVCDSPDAGTVKWPGPGMQEVAVPYDPHYMSSPTERYSQPVEERRISTRTAPLPTEKVKEPAPMTIEQQRQEKRKNRRVLEKELAEQARERRFQARRRLSKNPPPAPLLDEEEYICLFCDYEAIFGEPPRYLIRSFELRARNERIEEEKKRRRLEQVKARNRKGKKATTGKTPVSKGSTTGSTKTDTLPHEDDGDIPTHDGPHPEDDGGCLYDDCNTSGHSLGLGLGLGLGAAGIGDDDDDDDDGDAISTDDSYRMDSSDDGDADVEEAQLEDEFGGTIHAKIRDLTVRVHSPVLSTSNVELLLFIQYLVAKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z820</accession>
    <name>A0ABR3Z820_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-phytase</fullName>
            <ecNumber evidence="2">3.1.3.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_002928</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.8" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000062">
        <property type="protein sequence ID" value="KAL1896220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963">
        <property type="entry name" value="MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963:SF43">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_7G01240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00616">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00778">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="628" mass="68939" checksum="E14990B2F0470D93" modified="2025-10-08" version="1">MSSSSETLTPAPASRRSLSSQYLKPYGPESSRGPWIWRYQSVRNTVFTLLGVGLAFVILKQAYVDSAGRDYISSLVKEHSSNGSCHCLALPEPTATATVPDYFQTKPELFPGPTATGKAAFLAQTMSFDPLATTIYEPNTPLQTVLPISGMSGGSKNGKNSTTNRAPVNIFRLMGNLSPYQPADGFGVREYPLPPSAKIVQVQMLSRHGSRYPTTGSEVALFGERVANASDKISATDKLAFLNDWEYGLGAEILVPKGRQELFESGVLHSYMYGQMYDPNTKIIARTTTQDRMLKSAENFMAGFFGLDWAVNVTLELIIEKPGFNNSLAGYMNCPNANEESGGVEARSTWVNIYLKNATERFKSMITGFDWTIDDTYAAQTLCPYETVAFGSSRFCELFTYEEWEGFAYSLDLEFSASSGFQSPTGRAIGIGYQQEVVARLKNTTLDYSHSQINTTLDSSLNTFPLNQSLYLDFSHDSNIISVLAAFGLRQFAEPLVPSVNPGHRNFSVAQLTPFGARLDIELIETPHPMAADRSGYIGKDSKGGGNVTRYVHFVLNQRTIPLGLSFHECDVGRVDGWCELETFLKVQSKMAAVAQYDYACHGEMLNKQQFGKVTDGAPITTTTVTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z854</accession>
    <name>A0ABR3Z854_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">dTDP-fucopyranose mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">fcf2</name>
        <name evidence="5" type="ORF">Cpir12675_002796</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000058">
        <property type="protein sequence ID" value="KAL1896459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039883">
        <property type="entry name" value="Fcf2/DNTTIP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014810">
        <property type="entry name" value="Fcf2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21686">
        <property type="entry name" value="DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21686:SF12">
        <property type="entry name" value="DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08698">
        <property type="entry name" value="Fcf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fcf2 pre-rRNA processing C-terminal" evidence="4">
        <location>
            <begin position="69"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1896459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="190" mass="21227" checksum="4F520A0C7AC653A9" modified="2025-10-08" version="1">MTELTTQLDVDGLLAAAEARLANSATSTKLPVVLPMVNNALANRKETKAQELEVRQVESAAKSVSETEKKDTAGSGWFDLPETNLTPELKRDLQLLRLRNALNPKVHYKKQSWRSQVPRYSHVGEVIAGPTDFFSSRITKKERRNTFAQEVLAVEKSTGKFKAKYGEIQKVKTSGRKAFAKARRNALKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8D7</accession>
    <name>A0ABR3Z8D7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Probable Xaa-Pro aminopeptidase P</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Prolidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Cpir12675_002799</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the peptidase M24B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000058">
        <property type="protein sequence ID" value="KAL1896462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01085">
        <property type="entry name" value="APP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033740">
        <property type="entry name" value="Pept_M24B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032416">
        <property type="entry name" value="Peptidase_M24_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001131">
        <property type="entry name" value="Peptidase_M24B_aminopep-P_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050422">
        <property type="entry name" value="X-Pro_aminopeptidase_P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43763">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43763:SF6">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16189">
        <property type="entry name" value="Creatinase_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16188">
        <property type="entry name" value="Peptidase_M24_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00491">
        <property type="entry name" value="PROLINE_PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0464">Manganese</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase N-terminal" evidence="11">
        <location>
            <begin position="10"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M24" evidence="10">
        <location>
            <begin position="328"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M24 C-terminal" evidence="12">
        <location>
            <begin position="557"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1896462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="620" mass="68201" checksum="3A4B5B3A9C2F06C1" modified="2025-10-08" version="1">MDGYVNTSSRLEALRKAMKEHGVDIYIVPSEDSHSSEYTATCHARREFISGFTGSAGCAIISLDKAILSTDGRYFNQASKQLDSNWTLLKQGIQDVPTWQEWTAEEATGGKVVAVDPTLLPTSIAKKLAEKVKKTSGTDLLPLRKNLVDIVWGDARPALPNSIIKALPEKFAGKSVGAKLASLREELGKRKAAGIVISMLDEIAWLFNLRGADISYCPIFFSYAIVTPDSAILYVDKARLSADVRPELEKSNVQVKAYDSFFLDCARLAPQSESGSDSILSATPLNYLICNKASWALKLALGGDKNVDEIRSPVGDAKAIKNPTELDGMRQCHIRDGAALIGYFAWLEHELTVKHSTIDEVTAADKLEEFRKKQDMFVGLSFDTISSTGPNGAIIHYSPQRNNCAVINPNAIYLCDSGAQYLDGTTDTTRTLHFGVPTDFEKKAYTLVLKGNIALDTAIFPKGTSGFALDAMARQFLWKEGLDYRHGTGHGVGSYLNVHEGPIGIGTRVQYAEVALSPGNVISNEPGYYEDGSFGIRIENMAIVQEVKTKHSFGDKPYLGFEHVTMVPYCRKLIDTGLLTEAEKSWINESHADIHEKMKERFESDPIALEWLKRETAPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8V2</accession>
    <name>A0ABR3Z8V2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">5'-nucleotidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_002699</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000055">
        <property type="protein sequence ID" value="KAL1896677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07406">
        <property type="entry name" value="MPP_CG11883_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="entry name" value="5'-Nucleotidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041821">
        <property type="entry name" value="CG11883_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575:SF48">
        <property type="entry name" value="5'-NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="5'-NUCLEOTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="5">
        <location>
            <begin position="26"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="5'-Nucleotidase C-terminal" evidence="6">
        <location>
            <begin position="312"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="528"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="574"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="537"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="591"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="659" mass="72249" checksum="32897626B3B37BDC" modified="2025-10-08" version="1">MSLPSHASVTYKSNRPSDNPAAAYVRLLHYNDVYHLEQSSAEPVGGLARFVSVVNEYRKSAETKTTGLVTVFSGDAFNPSLESSVTKGEHMVPVLNTIGTDVACVGNHDFDFGVAQFSHLTSKCTFPWLLANVFDPALGDDVPLGGAKQTHWITTPTGVRIAFLGLGEREWLATINSLPPNIIYKSASAVAKEIVPKLRADGADLVVCVSHQREPNDNKLAENTDGLFDLILGGHDHYYAHAYIKGTHVLRSGTDFRNLSYIQGWKRTDGSGKWDFDILRRDICSDVAPDVEASALVENLTASLKHNLAKPVGWTAVPLDARFVTVRTRESNMGNFVCDIMRGHYGADAALMASGTIRGDTIYPPGVLLVKDITNCFPFEDPAILIRVTGQAIWDALENGVCQYPALEGRFPQVSNIVYKFDPKLAPGKRIVEAKLGGSPIVLDKKYTLATRGYMGRGKDGYSSLLVEPEGGVAEEIVCEENGILISAMMRQYFMGLRTVGKWRYLSTHWDAIAHKLVPLESADTTNIQKSFGKPNETTEVKNEAKKADESTGLTGTSAWNKWLNRRLGIGRRPVNDNGSVDGEAGAGDKEADDQDDNDDDEIDKIDSDILLLRKFFAKWARKAGVNTVVCDATKQEDLAVDWTRVIAPKLEGRIVMVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9F9</accession>
    <name>A0ABR3Z9F9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Uricase</fullName>
            <ecNumber evidence="5 6">1.7.3.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Urate oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_002416</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>urate + O2 + H2O = 5-hydroxyisourate + H2O2</text>
            <dbReference type="Rhea" id="RHEA:21368"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
            <dbReference type="EC" id="1.7.3.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Purine metabolism; urate degradation; (S)-allantoin from urate: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 6">Belongs to the uricase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.7.3.3" evidence="5 6"/>
    <dbReference type="EMBL" id="JAWDJO010000047">
        <property type="protein sequence ID" value="KAL1897234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.270.10">
        <property type="entry name" value="Urate Oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002042">
        <property type="entry name" value="Uricase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019842">
        <property type="entry name" value="Uricase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03383">
        <property type="entry name" value="urate_oxi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42874">
        <property type="entry name" value="URICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42874:SF1">
        <property type="entry name" value="URICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01014">
        <property type="entry name" value="Uricase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000241">
        <property type="entry name" value="Urate_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00093">
        <property type="entry name" value="URICASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00366">
        <property type="entry name" value="URICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="3 5 6" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1897234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="304" mass="34271" checksum="066E42AF504AF539" modified="2025-10-08" version="1">MPAIASARYGKDNVRLYKVDRNQETGVHTVTETTVCCLLEGDIETSYTLADNNVVVATDSIKNTIFIKAKEHPVTPPELFSGILGKHFLEQYSHIHVANVKIITHRWKRMEIDGKPHPHSFYRDGNEVRVVEARVTRDSTSVKSSIQGLLVLKSTGSAFHGFVTDEYRTLPDTFDRILSTEIDASWVWKFESHDELVKSVPKFDKAFDDAREITMEIFAKDNSASVQNTMYKMAERILEVVPEVDTVSYTLPNKHYFEVDLSWHKGLKNTGPDAEVYAPQSGPNGLIKVEVVRTKPLTVNSVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9H3</accession>
    <name>A0ABR3Z9H3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mitochondrial distribution and morphology protein 10</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Mitochondrial inheritance component MDM10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">MDM10</name>
        <name evidence="8" type="ORF">Cpir12675_002432</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. Associates with the mitochondrial outer membrane sorting assembly machinery SAM(core) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Mitochondrion outer membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <text evidence="6">The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.</text>
    </comment>
    <comment type="domain">
        <text evidence="6">Lacks alpha-helical transmembrane segments, suggesting that it resides in the membrane via beta-sheet conformations similar to those predicted for other outer membrane proteins and porin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MDM10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000047">
        <property type="protein sequence ID" value="KAL1897249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03102">
        <property type="entry name" value="Mdm10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027539">
        <property type="entry name" value="Mdm10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28035">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28035:SF1">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12519">
        <property type="entry name" value="MDM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 6" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1 6" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="331"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="407"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="334"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="374"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="407"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="567" mass="60501" checksum="FBE0780A4F1A1A1C" modified="2025-10-08" version="1">MREFMEAVQKAFYDATGWHRDNSYSSLDVTADGLLNFQTPQGLHMTLSSLATPQFATSYELGTIGVVDGSISYLYSSVPVQRYFTPQSEKVSLPSRMQSYRSLSPLNTGTSASKVTLNGSSATSKISYPSLLYGRLYLPQSMLEALVVKKLSSALQVQLSAVSSKTLRNGGTVLGLAQCDVGRYAIEGLASSDGGLLGLRGIYNFHAHDEKAPLPFPGDGERERIFGRFSTGAEIYYGTLNKSGGISLGARFATLPEHMGTPLTATLTINPLMGSISASYAVMAGKLCTLGTRLDFNVYSYESHWMVGIELWRKSFPSRVAAISDTVELDKSKTANTKRPSTQKQTENMAMTSQKPKPLVGQALGSTMKPVPAQSPQNNSSAELPAAQTSGFERSFQAKIEWRLDAPPAISPPASAATAAATSSATGTKPSSPLGNSPAPASPLYTPSTPPLVSTSVYVTPLTTGPTSLTKSQGSLAATGVTKSFVPAVISGDDASAGVTVTAVTLPGNDSEEYREVIKVRLDQNMRIGLLWEGRVKALLFGLGFAIDFRRRDQPFRTVGLEVQYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAZ4</accession>
    <name>A0ABR3ZAZ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cleavage and polyadenylation specificity factor subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002467</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000048">
        <property type="protein sequence ID" value="KAL1897210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18871">
        <property type="entry name" value="NUDIX_Cfim25_Nudt21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016706">
        <property type="entry name" value="Cleav_polyA_spec_factor_su5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13047">
        <property type="entry name" value="PRE-MRNA CLEAVAGE FACTOR IM, 25KD SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13869">
        <property type="entry name" value="NUDIX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="291" mass="32598" checksum="046D2AD32794816B" modified="2025-10-08" version="1">MTTIAPDMLQTSQPPVIPMPFNAQQPPTLRLYPLSNYTFGVKETQPEEDASVVARLHRLEEHYGKHGMRRTCEGILVCHEHNHPHILMLQIANAFFKLPGDYLMPDDDEETGFKRRLDERLAPMVEGEIDGPAGEWEIGDCLAQWWRPNFELFMYPFLPPHVTRPKECKKMYMIRLPENKALSVPKNMKLLAVPLFELYDNTARYGPQLSAIPHLLSRYNFEFVDEKGNVAAITPGYSAPDGYVPYTRVLAGKDTEDSGSGSGGDNKATTAADKTKKDGQGDSGMDDAQGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB84</accession>
    <name>A0ABR3ZB84_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_002406</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000046">
        <property type="protein sequence ID" value="KAL1897300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF43">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G03040)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="358"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="388"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="453"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="512"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="89"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="31"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="32"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="572" mass="60887" checksum="9825721CBD40F6E7" modified="2025-10-08" version="1">MPVSSARFSLPYPNLSFSDFAVLTEPPPPLPVLSTPPSATSSPLNGLNMAAGSGTSPGPSPRDRRSRATTVDVVPIQGPQLTRARQTVIMIGCLLGLFFSSLDAGIVSTSLVTISREFDDSISAPWVILAYLLTYMGFAVCVSRLSDIYGRRDVLLISWIIFNCFSMGCGASSSMKQLIICRAFQGIGGSGLYSLAQIAVVEMGPIRTPSLVGAMIGITLAIALVLGPILGGLISYYAGWRWIFNMNIPAGMAVSLLLTLSWPVSLREIDSPLSRYTWTSFTSIDFVGSGTLLCSCCLLIFALQQAGSGVSMWDSPGIVTAFTFAFIVTLLSGFPYFALTVAVPERFQVINGDNPLLAGLHLIPLLGSCAIGSFLAGALSSKRNNTSVTLIASSCLQLLGLGLMTTFSTANADVKPQYAFQAIIGLGVGMCFGSSTIIAALQIRNEDLASAQGAVAQARVLGGCFGLVMLTIVSHKASTDNALLNLELEPSTEIPQVSKDAYAAAFARETRIMVYVAVAMVLLSLFAWERNPVAMSVLAAHQHKDIRNSTETATEMSDMGSIRSYRARRFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCI1</accession>
    <name>A0ABR3ZCI1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribonuclease H2 subunit B</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ribonuclease HI subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_001979</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000034">
        <property type="protein sequence ID" value="KAL1898353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09270">
        <property type="entry name" value="RNase_H2-B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040456">
        <property type="entry name" value="RNase_H2_suB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019024">
        <property type="entry name" value="RNase_H2_suB_wHTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041195">
        <property type="entry name" value="Rnh202_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13383">
        <property type="entry name" value="RIBONUCLEASE H2 SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13383:SF11">
        <property type="entry name" value="RIBONUCLEASE H2 SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09468">
        <property type="entry name" value="RNase_H2-Ydr279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17745">
        <property type="entry name" value="Ydr279_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rnh202 triple barrel" evidence="8">
        <location>
            <begin position="42"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Ribonuclease H2 subunit B wHTH" evidence="7">
        <location>
            <begin position="130"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="249"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="357"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="254"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="362"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00033464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1898353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="418" mass="45878" checksum="38062818F4805F6B" modified="2025-10-08" version="1">MARTTRSTKALASAVADSTTTSKTSSKVHSLPPAANPQHIFVLPKRATPNARIITLPNPRSGKPTRYYACPITGLYEFTQVSSDEPRSWLIESPTTSVPAVEATKVAHSSELTTISDADLFIATEIDPVFHLISALYKETSSDEKPRYLSADDQLDKIPSDGSHLWSILKWKGMRKIFEDRLSAICTTAELAGETMYCLNEAKLYDLVLSKASRLAENGLPDSLEDKFVTKVLESPMVFQAAIPGAVLGDTNETSSDSTAPSTDTAKPQPFADSESTPAKPATDIDGFAGGSFVAVKIPEDVLALQRIFIAFKFICSKYVPESLDVSLKMHLKEKMDFGPLDTYLAKLVKTRSEAVASRSSDMSRKHPLEDAKDLLQEKKRKVEEEAKKKKLVSRGVKNLKKANTTGMKKLSHFFKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDA7</accession>
    <name>A0ABR3ZDA7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA helicase</fullName>
            <ecNumber evidence="4">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Cpir12675_002080</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000037">
        <property type="protein sequence ID" value="KAL1898061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18044">
        <property type="entry name" value="DEXXQc_SMUBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050534">
        <property type="entry name" value="Coronavir_polyprotein_1ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048761">
        <property type="entry name" value="SMUBP-2_HCS1_1B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788:SF8">
        <property type="entry name" value="DNA-BINDING PROTEIN SMUBP-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21138">
        <property type="entry name" value="SMUBP-2_HCS1_1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="203"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="221"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="528"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="529"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1898061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="692" mass="75969" checksum="EBECEB42D46CF5AD" modified="2025-10-08" version="1">MTAKAVNIPAFAQSQLGLLAAELQAETAEAESLISSHTPTALQRAGYAITNLVISNSRTGLGGKTVLELSPDSATAGADAELPAHGLRSGDIVLVAGQPAGSAKKREAKDLEKKGIRGVITKTVRSTVSVALDQERDEEPTGRLWIVKLADEVTYKRMTQTMERMQRMTESDYTPFMRALFGLSSLSPVDNIPLDGEGSIEWVDETLNQSQKDAVRFALGSREVALIHGPPGTGKTHTLIELILQMVKLGQRVLVCGPSNISVDNIVERLSPHKVPMVRLGHPARLLPTVLNHSLEVLTRTSEAAAIVRDVRVEMDTKQASIRKTRTGRERKQIYGELKELRKEFRERERNCVTSLVRGSKVVLATLHGSGGHQLRDERFDVVIIDEASQALEAQCWVPLLSASKAVCAGDHLQLPPTIKSLNSKSKKSALPTTNFPIPGEVFVPTGSLETTLFDRMLALHGSNIKRMLTTQYRMHEAIMRFPSDQLYNSELMAADTVKERLLCQLPDVEDTEDTNCPVIFFDTQGGDFPERTEDNSEGSKAKIHSVTSESKSNEWEAALVKSHVKALVAAGVKPECIAIVTPYNAQVGLLAPLKEQYPGIEVGSVDGFQGREKEAVIVTLVRSNSNGEVGFLGEKRRLNVAMTRPKRSLTVIGDSETIKRGSKFLGKWMDYLEENADLRYPDVSELQQQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE03</accession>
    <name>A0ABR3ZE03_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribonucleotide-diphosphate reductase (RNR), small subunit</fullName>
            <ecNumber evidence="3">1.17.4.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RNR2</name>
        <name evidence="3" type="ORF">Cpir12675_001956</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribonucleoside diphosphate reductase small chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000034">
        <property type="protein sequence ID" value="KAL1898331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01049">
        <property type="entry name" value="RNRR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="entry name" value="Ribonucleotide Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033909">
        <property type="entry name" value="RNR_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030475">
        <property type="entry name" value="RNR_small_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000358">
        <property type="entry name" value="RNR_small_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23409">
        <property type="entry name" value="RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23409:SF18">
        <property type="entry name" value="RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00268">
        <property type="entry name" value="Ribonuc_red_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000355">
        <property type="entry name" value="NrdB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00368">
        <property type="entry name" value="RIBORED_SMALL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="375" mass="42696" checksum="54DA28677654EEBD" modified="2025-10-08" version="1">MAFNVTASQQLSFENKPDMAIADNAKKPVEEKKVVATIKASEADEPLLQENPNRFVLFPIKYHEIWQMYKKAEASFWTAEEIDLSKDLHDWNNRLNKDEQYFISHILAFFAASDGIVNENLVERFSGEVQIPEARCFYGFQIMMENIHSETYSLLIDTYIKEPSQRTYLFNAIDTIPCIRRKADWALKWITDKESTFAQRLVAFAAVEGIFFSGAFASIFWLRKRGLMPGLTFSNELISRDEGLHTDFACLLFSHLNNRPSKDLVQKIITDAVVIEKEFLTEALPCGLLGMNADLMKQYIEFVADRLLVALGNEKVYRATNPFDFMENISLGGKTNFFEKRVGDYQKAGVLNSANKVSGEANQASSDAFALDVDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE17</accession>
    <name>A0ABR3ZE17_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ATP-binding cassette, regulator of translational elongation</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">GCN20</name>
        <name evidence="6" type="ORF">Cpir12675_001972</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000034">
        <property type="protein sequence ID" value="KAL1898346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF117">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="198"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="530"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="122"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="281"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1898346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="750" mass="83175" checksum="FB0169AD55FB878C" modified="2025-10-08" version="1">MDAEIRRIIPNIDPILSEYSTGYLTHVSTSTVDEESNAVAPIVEAAERITELLLSASGTPSKDQEEKIRTLVSKWATKYSEIYGSEDHGSSAAIRRLDQAFQVGAQRNMSSTLAVSTGAVDLESANSRKVESKVDKKKLEKAERKIAAKQQKKEFKTVEYEASRLLNQTESAQSYEEFYMAVNPLQLGGSGGNKTKDIKIDSIDVSIGGQRILTDTNFTLAFGHRYGLVGNNGVGKSTLLRALSRRELPIPTHISILHVEQELAGDDTPAIQAVLDADVWRKMLLLEQSELTENLTDLESKRANMADTSADAAKLDHEREVLDTRLGDVQGKLAEMESDKAESRAASILAGLGFSAERQQFATKTFSGGWRMRLALARALFCEPDLLLLDEPSNMLDVPSITFLSNYLQNYPSTLLVVSHDRAFLNEVATDIIHQHSERLDYYRSANFESFYATREERKKQAKKEYEKQMGERAHLQAFIDKFRYNAAKSSEAQSRIKKLERMPVLEPPEAEYSVKFKFPEVEKMTPPIIQMTDVTFGYSPEKTLLRNVDLDVQLDSRIGIVGPNGAGKTTVLKLLIGKLTPTGGLISQNPRLRVGYFAQHHVDALDLDMSAVSFMAKMYHGRTDEEYRRQLGAFGITGTTGLQKMGVLSGGQKSRVAFACLALTNPHILVLDEPSNHLDIEAMDALSEALQKFEGGVLMVSHDVTMLQTVCTSLWVCDDGTVEKFDGDVQMYKKRITAQADAAGVVQAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE57</accession>
    <name>A0ABR3ZE57_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Signal recognition particle subunit SRP72</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">srp72</name>
        <name evidence="12" type="ORF">Cpir12675_001709</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the SRP72 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000028">
        <property type="protein sequence ID" value="KAL1898956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013699">
        <property type="entry name" value="Signal_recog_part_SRP72_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026270">
        <property type="entry name" value="SRP72"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031545">
        <property type="entry name" value="SRP72_TPR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14094">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14094:SF9">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE SUBUNIT SRP72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08492">
        <property type="entry name" value="SRP72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17004">
        <property type="entry name" value="SRP_TPR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038922">
        <property type="entry name" value="SRP72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7 9" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="Signal recognition particle SRP72 subunit RNA-binding" evidence="11">
        <location>
            <begin position="552"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="546"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="565"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR038922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1898956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="640" mass="69230" checksum="BDD9E8352567BB7B" modified="2025-10-08" version="1">MAPSLTAALKAATLNDHEAILNAANASLKTSKNDTFANHTRIVALLKLDRFEDVLRTVSRLDENIKSQFSLETAYAMYKLGQLDDAAQVLSTCTPKTEAVQQLEGQIAYRAERFEDAWKMYNSLEDCNYSDDLYINKTAVLAQLGWQGKGSDCCVANPETITAFEVAYNLACLQISKGNLMSALHLLQVSKKLCDELDDLSDEEKQGELVPILIQQVYVYSRLGCTKRAKELQKLLVISDDCGEDTKSLARVNSAILSSIEASNRFLAQRNIEGPISMANGQKLFNYQLSSLRQLQLVLDLSIQKYKGTDSIAKAKSKSGPATSAAVNGFAPIGIAALSWMSPEKPLAIATDLLEKRPCDVGLALAVIQLCVKEGLTDVAISHMESILKKLGAMEEIGALQVRYSPGLIAVAVSLYKLAGRNCMARAELRKAACFWQKYPETTSKSLLVEAGLELLKSDKIEDHMLASETFSLLLASDVKNKMAISGLVAAVAGTDQKKAEALAVEIPGVKALTKDSNVSALLEAGVASNTKVNSGIKRGLAISSASGAPVSKKRRQRKLPANFEEGKIADPERWLPMRDRTSSRPKGGKKGKKKAEALTQGGYVKGEETLELVGGVGAVKVEKTPQVSTAAKKKKKGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE89</accession>
    <name>A0ABR3ZE89_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Protein kinase</fullName>
            <ecNumber evidence="8">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">BUB1</name>
        <name evidence="8" type="ORF">Cpir12675_002041</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
            <location evidence="1">Centromere</location>
            <location evidence="1">Kinetochore</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000036">
        <property type="protein sequence ID" value="KAL1898093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd13981">
        <property type="entry name" value="STKc_Bub1_BubR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015661">
        <property type="entry name" value="Bub1/Mad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013212">
        <property type="entry name" value="Mad3/Bub1_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012572">
        <property type="entry name" value="Mad3/Bub1_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14030:SF4">
        <property type="entry name" value="BUB1 KINASE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14030">
        <property type="entry name" value="MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08311">
        <property type="entry name" value="Mad3_BUB1_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08171">
        <property type="entry name" value="Mad3_BUB1_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00777">
        <property type="entry name" value="Mad3_BUB1_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51489">
        <property type="entry name" value="BUB1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0137">Centromere</keyword>
    <keyword evidence="2" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BUB1 N-terminal" evidence="7">
        <location>
            <begin position="63"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="998"/>
            <end position="1379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="16"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="242"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="421"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="627"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="831"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="424"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="448"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="642"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="709"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="755"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="798"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="837"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="858"/>
            <end position="872"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1898093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1379" mass="155598" checksum="E1BEF0C4AF8810AD" modified="2025-10-08" version="1">MSDAQDPVDFEILEGQKENIQSLPGGHSARKLAQLYSPNPLKPLSTPNPADTQDAHSAKRTEFEQEVAAIDESDDPLDVYDRYVRWTLEAYPSAQATPQSQLDQLLERATKSFVSSAQYRNDPRYLKMWVYYIQFFSDAPRETFLFLSRHGIGESLALFYEEYATWLEGQGRWAQAEEVYKLGIECEARPQARLLRKFKEFEHRMSEQPAESVRPTSPAIPPVRAALATKVDPFAIAMLPDDPQAPRPSAGLPGYASPKGNKTKGKMAIFSDSSAKEPAMSERATTGPRGWDSIGSLSERKKENVIEPKPWAGETLKAGGKKPSGPKMAIFKDTYKISSASDQVVVNPRTGKMERILVDLEVIYPQPDVRGAELSFEEVWAQNRGWLDRSWEEEEGEERKMTMIDVDESVSQYDESFILQQQRRQNEEEQRREQEQEQQKKPVHRQKKLEMYHDDTSISRDENSPIQGTSRLEHQNMAIRRDSFEARSYKMQIHRDGVVPQKQKLSIHHDDEPVVPKKQKMAIHHDEFVDEENRLASSLSSPVARPPVQKIPIHRDEPVDENGMVIQQQQKPVKSKKKIMDYNETQIIKAKLDSPSRPKISKRTSIAADPTMTIHTKSATDDIYDIFNAPLPSKTGDKGGSDDDEEYGSDEYESDGESMGTTRNVDLEDSDDDDAKSDWSDYTIKKKASGLDDLTCKTNPDFTVRGVIDDEEEEEEEEEEDDDDDDDDESDGEEEEETEAEEQSEISEMRGPDECNQSSQFSEQEPSLQSVENGLVTQIGQQSQQQQSRTITHTKFIPVPPEDYVPPTRPYRDPAEVANNRLPFMTPITERTEMSLDFQQTQGKTPSRSRGTMHSMPEEDEDEDEDEDEDEEEVYNSITDINEAMSSPLIDMGKSPISYNIKIAQPAFPKPTTKALAPKGPIIKDLQINPMDEGIRSQILNKTRPPLMTYVGFFDHRDQNYEKGNEIRRFARAMSKAKSSGDHLAGPVIRLPDSQGMYTVKKELGAGAFAPVYLVENSAPYSSQADEAIVLLGPKAPLSRHRNHLEALKMETPPSLWEFFMMRLTHNRLGPQDRAAASLSYAHELHLYKDEGFLVLPHHPHGTLLDVVNHFRAEPSGVMDEQLAMFFSIELLRTVEALHSKAIMHGDLKPDNCLLRIDAASSASRPASALVTFGSVGSPDPETTVLTPQYHVDGSGGWATRGVTLIDFGRGIDMRAFVADQVQFIADWKTTSQDCAEMREGRSWTWHIDYHGLAGIIHTLLFGKYIETVRMDQGPGTTGGISGTAVGGPLNIGIGSRKYRIRESLKRYWQTDIWAECFDLLLNPGHFVERDGEGGRMPVTRGLRRVREFMEEWLSANCERGAGLKTLVNKVEAFAKGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEC1</accession>
    <name>A0ABR3ZEC1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001576</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000026">
        <property type="protein sequence ID" value="KAL1899020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052635">
        <property type="entry name" value="Sec_Metab_Biosynth_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39607:SF2">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39607">
        <property type="entry name" value="XANTHOCILLIN BIOSYNTHESIS CLUSTER TRANSCRIPTION FACTOR XANC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="56" mass="6338" checksum="10EE2EA3D57DA0E9" modified="2025-10-08" version="1" fragment="single">MSSNPSKEPERSSSRTPSGASSSGKGKRQSKSDDWSEVTDPEERRRIQNRIAQRKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEY6</accession>
    <name>A0ABR3ZEY6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">nitric oxide dioxygenase</fullName>
            <ecNumber evidence="2">1.14.12.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Cpir12675_001783</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>2 nitric oxide + NADH + 2 O2 = 2 nitrate + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19469"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.14.12.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>2 nitric oxide + NADPH + 2 O2 = 2 nitrate + NADP(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19465"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.12.17"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.12.17" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000030">
        <property type="protein sequence ID" value="KAL1898676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08922">
        <property type="entry name" value="FHb-globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06184">
        <property type="entry name" value="flavohem_like_fad_nad_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="entry name" value="Globins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000971">
        <property type="entry name" value="Globin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43396">
        <property type="entry name" value="FLAVOHEMOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43396:SF3">
        <property type="entry name" value="FLAVOHEMOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00042">
        <property type="entry name" value="Globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="Globin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01033">
        <property type="entry name" value="GLOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0216">Detoxification</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Globin" evidence="11">
        <location>
            <begin position="2"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="12">
        <location>
            <begin position="150"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="329"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="329"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="357"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1898676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="538" mass="58555" checksum="D58946D575B7E7C6" modified="2025-10-08" version="1">MSLTYQQAKLVKETIPILSSHGDLITTIFYRNLLNAQPSLSAIFNNANQLNGRQPRALTQIILTFAQHIHRMSELAPILERVCHKHVSLNISPADYDIVGKYLLGAFSTVLGPTIFTAAVAEAWERAYNILARMLSGREAQLYASLGDWVGFRPFCIMRKVQETRTRDVFSLYLVPVDGSMLPLPSFKPGQYVSLQIPVKCYEDVATQTRQYSLSDKPRGDYYRITLKREINANGGPGMVSSELIDNYGIGDIVQLSHPTGDFFLDMENSGSSVPVVLISAGVGVAPMISILNSLLAQVPTPPSTSSSSSSSSRINPISSKNSIASSFQAASPSSTHSSVPSFFSRSRTHSRAPSMPSLSPANRTASFSFSSSGLSRGSVDSTSTSSPEPEPGPKQELAESLAATATLANHVVAPRLPACRPITWIHGSHADAAFDIYIRSIAHMRRNFHSAVFKTAPEAGDILGSDFNFTGRVDLDKISDADLHLTYGAAEYFICGPEGFMLDVRKALLRKGVDVSRIKCELFNTGDLLANAKWKWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF79</accession>
    <name>A0ABR3ZF79_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000023">
        <property type="protein sequence ID" value="KAL1899358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038769">
        <property type="entry name" value="MTC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38426">
        <property type="entry name" value="MAINTENANCE OF TELOMERE CAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38426:SF1">
        <property type="entry name" value="MAINTENANCE OF TELOMERE CAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="412"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="533"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="631"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="703"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="785"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="866"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="947"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="533"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="554"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="607"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="631"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="742"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="786"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="876"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="952"/>
            <end position="967"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1237" mass="138612" checksum="189D3A2C9064D7E0" modified="2025-10-08" version="1">MDDDDGAAPSQASADTRPRVNTAFERTSTPSRALPRSSHQSRDASHDYSHNAKYDLSPDIPQSSFIPSIPKIQSNSHGNSLNSSGRQRSSKDASADRSRWRNLKVRHNGGFLLSDMQSNVRSTSAEQKGKEVAANYSSHGGLGIGNRPGPIPHSSKTHSLLDKGSGLHSSELHVRGTRSAYSDRPDSADTDNSATSPSVGTDTAQIVDMALRINQNRRIASQRSAIQQLPPRLMPLPDTNASETLRHHLQQQRKLSRTSSPRPERMSGQRFPSASGKSSLPIQPGFDHTMPFEVPYRYNLSQSTLARVQKARQHLELMAHYRNLHNFLPPIPTRAEAKNMISPPHTPGGTTSLPAQSSESSSNLGRQYNPLQYIRNRKIRARERKAVYGEILGFANVSRVAEWVQEVAQRATQGSSVASDDGSLPPFQTAEERAHETAASIKQHGSNKPRRPRLEWEMEPADMIADIYWLEKGNNKQYMQDREWRPIFPPSSFPPTKPQSIESLNGISRQNTDVNLPSLSQRVASKLLDGEEHGHHHYDMHDSKHGFDNDHSHSKTAKARHKLHTFKLAHKYSNPNVNHHDAYRRSRNSLSEDSESEVDARFRRPNRSNTLTSQSKDILEKQMREIIAREMEQQKQQQEREQYQPAPQPPVLSSPISSDRMIDSVFKPISRIQSRPGSLLDSSEAEDRFPGREMEKKASIYNHGHRPGITTTARSSLEVPRQSFDMDQSRPVTPNSDIIEASDSSRPSSPSRNPFHRVKSILRDRSKERFHEQICERVPEEPEIMQTRTTSTSDLKSGFGRRGSSTPVDVDKEKDVLEMTRLAKKPINRLDGTNSSVRGMLKTPGLRIDNVIRGGFSKLGGLIWRKTDSDSDSESSDDKDCGRFSRNDSDCIGESEPRDVKSKQDCEARNDGNGLIATTPVCLNGNEDSWPHIDALKPPRIDIQAASPLSNCSRAPSTSSSDSLSSEVKSHEPSAPLIVHIPPWVQSASDGPIALRPRQPKEGSLARSFSPSHSPISRYDLARLRTLILSSAIKAREFDRMSSKPQFTFVESGALPNMPSKPSISIARSLIHDVCRLSKTMDSPLAGRCVSIIELHHLAAQTYSQAQASHEAEWQRIAAQFSAQTTVKLHAEIEAVRSLITADLLQFTRRTADEADEASRGMAMSQGLKAKRVEESIEKMLRRKRRRFRWLRRGMWLGLEWVLIGIMWYVWFVVTIMQIVLGVGKGVVRGVRWLFWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFB3</accession>
    <name>A0ABR3ZFB3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA excision repair protein ERCC-8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_001754</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000029">
        <property type="protein sequence ID" value="KAL1898751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042238">
        <property type="entry name" value="Rad28/ERCC8/Ckn1/ATCSA-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46202">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46202:SF1">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101898">
        <property type="entry name" value="NHL repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="63"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="124"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="211"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="287"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1898751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="482" mass="53760" checksum="AB8A7BD1F893ECCE" modified="2025-10-08" version="1">MNQLLYARETGEISGRQFAANITNDLLRSFELYPHLYFDGSFNIPLNSPPTSKLSSKTQARDFEAHYGGVNSLTVDKFYGRYLATGGSEGSVKIWDLEMCKDFTTEFTFRPKTAISRVRPDYRRYGHTSGVTHIEFHSRDENIIHTSSYDETLKQWDIERDKASASFDLRVPINTFAASPIVSPDNLIACAMETPQIRLVDTRTASTSRAMTSHGGGVFSLAWSPIKERILCSGHEDGTVKIWDSRRFSHPVAMLDQEDTLGVMHHFTHASLSGVPWTKARHFRSSARAHDDTVNGLAWTDDGNYIVSAGLDRHVRVWNAATGANTLVGFETSFQNYEALNISLIVSPGRLSYMSREVLYIPNGSEVAALELRTGKAISQLRVPGNTTVRRARNSRTVKAIAWRGSQGHGRPLGSAIGGANTYGAIYAAYGDGKIRAFMPNMPVVEDVDLDPTTKEQETKKRKRKAVDDAYRRLMGTQMRFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGF1</accession>
    <name>A0ABR3ZGF1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Sulfite reductase [NADPH] subunit beta</fullName>
            <ecNumber evidence="11">1.8.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MET5</name>
        <name evidence="11" type="ORF">Cpir12675_001532</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>siroheme</name>
            <dbReference type="ChEBI" id="CHEBI:60052"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.2" evidence="11"/>
    <dbReference type="EMBL" id="JAWDJO010000025">
        <property type="protein sequence ID" value="KAL1899249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004783">
        <property type="term" value="F:sulfite reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07034">
        <property type="entry name" value="TPP_PYR_PFOR_IOR-alpha_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.480.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="entry name" value="Sulfite Reductase Hemoprotein, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.480.10">
        <property type="entry name" value="Sulfite Reductase Hemoprotein,Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005117">
        <property type="entry name" value="NiRdtase/SiRdtase_haem-b_fer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036136">
        <property type="entry name" value="Nit/Sulf_reduc_fer-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006067">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045169">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006066">
        <property type="entry name" value="NO2/SO3_Rdtase_FeS/sirohaem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010029">
        <property type="entry name" value="PRK13504.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11493:SF47">
        <property type="entry name" value="SULFITE REDUCTASE [NADPH] SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11493">
        <property type="entry name" value="SULFITE REDUCTASE [NADPH] SUBUNIT BETA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01077">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03460">
        <property type="entry name" value="NIR_SIR_ferr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01855">
        <property type="entry name" value="POR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00397">
        <property type="entry name" value="SIROHAEM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="Nitrite and sulphite reductase 4Fe-4S domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55124">
        <property type="entry name" value="Nitrite/Sulfite reductase N-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00365">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="10">
        <location>
            <begin position="744"/>
            <end position="893"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1899249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1479" mass="163875" checksum="7B2C5A1223FDE930" modified="2025-10-08" version="1">MSRTLAIGSSSEAVARIAYLSSDVIISVQPSLDSESEFSPWLKAHVTQQTKSLVASSESKTPEVIPVRFNADPLLSAFTPIRSGRLTTITTSSNILIPSIGHLYKLATYPVVIHVSLGPSTNPDYSAITSIRNVGWTFLQSETVQEAQDMALTAHALAIRSGKGVVHFFPSSIFASSESPVIPETPTVVKALLDSEAILKFQATTYNHTSIYSDEMTSAAPAPSEAEGAQKSTVATSEDIFAFATDIWSRLSEATGRQYRAFEYFGSATAKNCVFVFGANSHDFVEAVANAGPGETFANTGILTARLYRPWLGFKLVESIPKSVKKIAVLEQIRRKTTRWGPVLLDVLTSVKSGPGGVDAIVGHQLGHLTPATVNQALRGVVQNLTSEKPIQNLEVGVEVALSVDSGYKIETPKAETAYTKILNQLFGQRAFVANALTSENTGISKTITATPEFGFGSLLAHKEKRNRFISEAKSAASSKEFASDSPSKALAKWSLSLNGDSNRTNIAADEVIKSLESDNSDLSQKLLKNQDLFRKESLWLVGSDAWSYDLGNSGVHHVLASGQNVNMLIIDSTPYSERSAADATRRKKDIGLYAMNFGNVYVASTAVYSSYTQVLQAIMEADKFEGPSVVLAYLPYYGEHDSALTVLQETKKAVDIGYWPLYRWNPQNEIQDEPNFILDSERIKKELKDFLSRDNQLTQLMKKQPQYAASLAQDFGTEVRTQQKRQAKDAYDQLLEGLFGAPLTVLYASDNGNATSVAKRLASRGRARGLKSQVMTMEDYPLEDLSCEENIIFVTSTAGQGEFPQNGHALWTALKDNTELDLASVNYSVFGLGDKHYWPRKEDRIYYNKPAKDLDRVLANLGAKRLADVGLGDDQDPDGYQTGYQEWEPKIWAALGVDKVDGLPEEPAPITNEDIKIASNFLRGTIEEGLKDTTTGAISEWDQQLTKFHGTYMQDDRDIRDERKAQGLEPAYSFMIRCRLDGAVATPQQWIAMDDIATHLGNNTMKLTTRQTFQFHGIVKGKLKPAMQAINRAMMTSLAACGDVNRTIMCSPTLKHSIYHREIYECSQRISTRLLPATRAYHEIWLTGDEKKVQVAGEAVQDFEPLYGPTYLPRKFKITIATPPHNDTDVYAHDIGLVSIRGEDGHLAGFNLMAGGGMGTTHNNKKTYPQTGRMMGFVSRDQVDAACEKVMLVQRDHGDRKNRKHARLKYTIDDMGVDVFRRKVEELWGQKFGEPRPFKFESNVDVFGWVKDDVGLNHFTMFIENGRVEDTPEFQMKTGLRDIASKTKGEFRLTGNQHVVLSNISDEDLEETKALLKKWKLDNTQFSGLRLSSSACVAFPTCGLAMAESERYLPILIGKLETYLEELGLRHDSIVMRMTGCPNGCARPWLAEVAFVGKAYDTYNMYLGGGYHGQRLNKMYRQSIKEDEILATLKPLLKTYALERDEGERFGDFLIRVGVIKATTDGTNFHDGIPEGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGH2</accession>
    <name>A0ABR3ZGH2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">SNF2</name>
        <name evidence="16" type="ORF">Cpir12675_001252</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000018">
        <property type="protein sequence ID" value="KAL1899751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17996">
        <property type="entry name" value="DEXHc_SMARCA2_SMARCA4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
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        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014978">
        <property type="entry name" value="Gln-Leu-Gln_QLQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014012">
        <property type="entry name" value="HSA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029295">
        <property type="entry name" value="SnAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10799">
        <property type="entry name" value="SNF2/RAD54 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07529">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08880">
        <property type="entry name" value="QLQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14619">
        <property type="entry name" value="SnAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
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        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="QLQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01314">
        <property type="entry name" value="SnAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51204">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51666">
        <property type="entry name" value="QLQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="QLQ" evidence="15">
        <location>
            <begin position="153"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="HSA" evidence="14">
        <location>
            <begin position="407"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="588"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="899"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="11">
        <location>
            <begin position="1321"/>
            <end position="1391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="68"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="402"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="520"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1175"/>
            <end position="1282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1421"/>
            <end position="1445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1475"/>
            <end position="1501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="119"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="532"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1185"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1213"/>
            <end position="1227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1431"/>
            <end position="1445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1488"/>
            <end position="1501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023117"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00023163"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
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            <dbReference type="PROSITE" id="PS51204"/>
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    </evidence>
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            <dbReference type="PROSITE" id="PS51666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1899751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1501" mass="170185" checksum="A0037A220A63E286" modified="2025-10-08" version="1">MATLPSPMMPQHQGLPLSMSINKQEVEAAVRKLKDMKDQGIPQTDPDFIKTQNFIKSVQQLHMRNMQQQEFMRRQQQQQQQQQQQQQQHQQPPPQQSPIQDHRSPNGLFNGNTGPGPDRSQTASIGPSNGASSPTASTTLNTSGSQAPSVASHFSTQQLALLRNQIGAFRMLSKNAGVPQSVQQTLFAQRLRRKMAVVEALSALAPASTGLSASPAPNQITVDPITAPLSNGDSASLAAANPNMTSASGRPAVTKGPLYTKYKTPLAAGLIKTAISFNDHASRSHRLFVPGMFPLGLDLDSVRYERETAIINRMRSRYAELKELPADLAHWDVSNPEVQPEETLKLKALVEKKAIEQFGRQRILRESVARQMLFFENLGTTTNRSRYRRVKKHNVREARITEKLEKQQRDARENRQRKKQDDFLRAISSNRNEINNLGISAAQRGHRLAKIMYNQHFNIEKEEQKRIERTAKQRLQALKANDEEAYLKLLDQAKDTRITHLLRQTDGFLHQLASSVKAQQRRAAEHYGNGGDIEESDEDNEPQDEETAGKIDYYAVAHRVKEEVTGQADMLVGGKLKEYQVKGLQWMVSLYNNNLNGILADEMGLGKTIQTISLITYLIERKQQPGPFLVIVPLSVLTNWNLEFDRWAPSVGKIIYKGPPNARRQQQDRIRQGNFQVLLTTYEYIIKDRPLLSKIKWFHMIIDEGHRMKNAQSKLSATIQTYYQTRFRLILTGTPLQNNLGELWAMLNFVLPNIFKSATTFDEWFNTPFANTGSQDKIELTEEEQILVIRRLHKVLRPFLLRRLKKDVEKDLPDKTEKVIKCKFSSLQSKLYKQMVTHNKIAVGEGKNGKTGARGLSNMIMQLRKLCNHPFVFDEVETVLNPLNISNDMLWRTSGKFELLDRVLPKYQASGHRVLMFFQMTAIMDIMEDYLRYRHFEYLRLDGTTKSDERSDLLRDFNAPNSKYFMFLLSTRAGGLGLNLQTADTVIIYDSDWNPHQDLQAQDRAHRIGQKNEVRILRLISSNSVEEKILERARFKLDMDGKVIQAGRFDNKSSETDRDAMLRTLLETADMTEQGDPDDMDDEELNEIIARNDNELKLFQELDDKRMMDPIYGNKPGCQSKPRLMAENELPEIYLNEGNPDAQEEEEVVLGRGARERTRIKYDDGLTEEQWLMAVDDDHDTPEEAAARKEARKDRREANRLRKVVLTNSVTDSTAVPPSPSQSQASTEEIETPKKRGRKPGSKNAEKRKADDGDEPPAKKRRGPIGRPKGSTNAPRDPNRLPPAQRALLQTSLRKLFDSLMNLETDDLLEPPPNDDESDPGKRLIIGPFVKLPPKREYADYYMIIQNPICMSQIEKKIKKEEYKKLSDMRSDIELMLNNCRTYNEDGSVLYTDANMMEDFFVDQLNKLLDEHVDLRAMEIPKPSQADVPGTAPASTAASTSATPTTDMSAVGAFADTGVNDSALPAVPPRIKLISNAGSKEAASAAPTDEDNENEGQEQEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGQ8</accession>
    <name>A0ABR3ZGQ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phosphatidylinositol-3-phosphatase SAC1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rsd1</name>
        <name evidence="7" type="ORF">Cpir12675_001368</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000021">
        <property type="protein sequence ID" value="KAL1899600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12283">
        <property type="entry name" value="RRM1_RBM39_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12284">
        <property type="entry name" value="RRM2_RBM23_RBM39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12285">
        <property type="entry name" value="RRM3_RBM39_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029123">
        <property type="entry name" value="RBM39_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006509">
        <property type="entry name" value="RBM39_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01622">
        <property type="entry name" value="SF-CC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48036">
        <property type="entry name" value="SPLICING FACTOR (PAD-1), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G15810)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15519">
        <property type="entry name" value="RBM39linker"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="150"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="248"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="442"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="407"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="16"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="61"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="89"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="105"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="417"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="539" mass="61311" checksum="7EA3B484A179B2F8" modified="2025-10-08" version="1">MATLDVEALLDSTAKGGEKKQSRSDISDTETARTESRRERSRSRDHGRDRDRASRSHSRSRSGDRDGRRRRSRDSDRNRRSRGDDYYRRRSRSRSPRGGGRRRRRDEYRSRRDRGDRYTGGGERKREDEPRKDRDGDSTPKNTEDERDRRTVFVQQLAARLRTRELKEFFEKVGGVMEAQIVKDRISQRSKGVGYVEFKQEESVAKALQLTGQKLLGIPIIVQVTEAEKNRQARNTEPGNHPNSIPFHRLYVGNIHFNVTEQDLQTVFEPFGELEFVQLQKDDTGRSRGYGFVQFRNADNAREALEKMNGFDLAGRLIRVGLGNDKFTPESTANMMHKFSGNGPNQGMHHNGLGSRGQATVFDRASRRDTDKPTNGNVSALDDTDVGGVNFNNYSRDALMRKLARTDEPPANTANGTEERQILKPKTETKPPLPVTVNSASRCVVLRNMFNPEEEEGDSWVKELEDDVRQEAEQKYGHVVHIAVDAHSKGDIYIKFDKVQGGENAIKGLNGRYFGGRMIDASPVVDTVYSSLFSRTRAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGS0</accession>
    <name>A0ABR3ZGS0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000025">
        <property type="protein sequence ID" value="KAL1899261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="335" mass="36508" checksum="5ABE0615DA84B2F6" modified="2025-10-08" version="1">MRPSRSSFATRRSNTAPALQTSMPMPPTIPMPMTPVSTTQSASAEPVISSNSLWMCGTSLVNHRGYERFHLRTTTYHGRSYIAIALPNENALLRISPLVPMSLTPYSSTSSTSSAIAAVRLEKAMLTDTQARQAPNFIRAMRSGVRNHLSNGRDRQSSSSHVSDREFTAPAFTPVTTRAASSDSHFSIASVAAAATVRPGVSVAALAKLFITKRSRSNTSNSGRLGLSLGLGLGLSRAKQSCLAIWEFLPTLTSIKGCHALIWRFKAVAQNSHETTWYRAPAEDDEAEFQLIAFEDVSCGFPRLIVHVAMEESAYHHLLGLWLTRLLDEAKCKAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHN5</accession>
    <name>A0ABR3ZHN5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_001347</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000020">
        <property type="protein sequence ID" value="KAL1899669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1899669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="96" mass="11041" checksum="6A00D66BCCD1B55C" modified="2025-10-08" version="1">MKLDDASEMTRAGMSRQKDAPSLIVRILVDESIKLHKKQVNEVLAELEKADMHLDVDNMEFDLKKTKYLSFIVEVEEQVSMDSAKTETNIFLEKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHZ3</accession>
    <name>A0ABR3ZHZ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein transport protein SEC13</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Protein transport protein sec13</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">SEC13</name>
        <name evidence="14" type="ORF">Cpir12675_001344</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat SEC13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000020">
        <property type="protein sequence ID" value="KAL1899666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037363">
        <property type="entry name" value="Sec13/Seh1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024:SF2">
        <property type="entry name" value="PROTEIN SEC13 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="11" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0811">Translocation</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <keyword evidence="6 13" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="13">
        <location>
            <begin position="60"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="13">
        <location>
            <begin position="215"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1899666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="310" mass="34113" checksum="5269CAF988DE2273" modified="2025-10-08" version="1">MEPRSQNSATSQVISNTGHDDMIHDAVLDYYGRRLATCSSDRTIKIFEIEGESQRLLETLRGHEGAVWCVSWAHPKYGNILASAGYDGKVFIWREQNNQWQKVFDFALHKASVNIVSWSPHESGCLLACASSDGFVSVLEFKDNSFDHKIFQAHGSGVNSVSWAPATSPGTIVSSTPSPAATGIRRFVTGGCDNLLRLWSFDAASQSYVQDGEPLTGHTDWVRDVAWSPTVLKKSYIASASQDKTARIWTSSNAITGKWGCKVLNFDSAVWKVSWSLSGNVLAISGADNKVTLWKENLGGEWECIKTVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI55</accession>
    <name>A0ABR3ZI55_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Methylenetetrahydrofolate reductase (NAD(P)H) met13</fullName>
            <ecNumber evidence="9">1.5.1.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MET13</name>
        <name evidence="9" type="ORF">Cpir12675_001030</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the methylenetetrahydrofolate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.20" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000014">
        <property type="protein sequence ID" value="KAL1900346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004489">
        <property type="term" value="F:methylenetetrahydrofolate reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00537">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004621">
        <property type="entry name" value="Fadh2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003171">
        <property type="entry name" value="Mehydrof_redctse-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053806">
        <property type="entry name" value="MTHFR_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00677">
        <property type="entry name" value="fadh2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45754">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45754:SF3">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02219">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21895">
        <property type="entry name" value="MTHFR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="FAD-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MTHFR SAM-binding regulatory" evidence="8">
        <location>
            <begin position="304"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF21895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="623" mass="69848" checksum="C90FF262B64FB1E4" modified="2025-10-08" version="1">MHISDKIANAKRAGEPSFSFEYFPPKTAQGVQNLYDRIERMNELGPQFIDITWGAGGRIAELTCDMVQQAQTIYGIETCMHLTCTDMGNTKIDDALSGAYKAGCSNILALRGDPPREKEKWEPTDDQFHYAKDLVSYIRQKYGNHFCIGVAGYPEGCDDNKDEDSLLDHLKQKVDAGASFIVTQMFYDVDNFLRWVRRVREVGITVPILPGIMPIATYASFLRRAKHMNCTIPADWLDVIEPVKNDDVAVRERGRKLVTDMCRKILASGLIHHLHFYTMNLAQSSRMIIEELNWLPSAERPIKQALPWKQSLGLGRRDEDVRPIFWRNRNKSYILRTQDWDEFPNGRWGDSRSPAFGELDAYGIGLAGTSEQNRAKYGTPESVRDIAELFVRYLKKDLESLPWSESALTGETSIISDKLIDLNSRGLITINSQPAVSGVKSSDPVHGWGPKGGYVYQKAYLELLVHPDVYPELIKRIESNPDMTYYGVTKTGELKTNAPSDGPNAVTWGVFPGKEIVQPTIVESISFLAWKDEAFRLGEDWARCYEAGSPSRQLIENIINNWHLINIVNNDFHQNDSIFALFSGLVVPGVNDVVPSSAPHSPTIAQDAGSVKGPTEIAVNGTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIA7</accession>
    <name>A0ABR3ZIA7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ribonuclease P protein subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_001553</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic/archaeal RNase P protein component 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000025">
        <property type="protein sequence ID" value="KAL1899269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.210">
        <property type="entry name" value="Ribonuclease P/MRP, subunit p29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00754">
        <property type="entry name" value="RNase_P_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016848">
        <property type="entry name" value="RNase_P/MRP_Rpp29-subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036980">
        <property type="entry name" value="RNase_P/MRP_Rpp29_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023538">
        <property type="entry name" value="RNP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023534">
        <property type="entry name" value="Rof/RNase_P-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002730">
        <property type="entry name" value="Rpp29/RNP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13348:SF0">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13348">
        <property type="entry name" value="RIBONUCLEASE P SUBUNIT P29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01868">
        <property type="entry name" value="RNase_P-MRP_p29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF027081">
        <property type="entry name" value="RNase_P/MRP_p29_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00538">
        <property type="entry name" value="POP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101744">
        <property type="entry name" value="Rof/RNase P subunit-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="202"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR027081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1899269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="248" mass="27280" checksum="3EBF08B586599845" modified="2025-10-08" version="1">MASKQQEAIVHSLLERAHSPTSTKRIYTEKVQYRPLLLRPSSPPPADQRQARRAVRQKAKALSKCKPALLSGRAARRRGLYALPRSGLQYATFAPLKALWEAYALDLLGSDVYPPAGGTGTGNMAGASAAAKLAAAEFHGAEVEVCRSKCTSRVGVRGIVVKDAQQTFELVTKKNKVKVVPKEGTIFRVRVPVPAPTQNKEGQGEEEKQPGEKAQDDVFVFEILGDQFMYRAPDRVNKKFKNHFLQAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJB2</accession>
    <name>A0ABR3ZJB2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000812</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047325896" evidence="2">
        <location>
            <begin position="20"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="181" mass="18248" checksum="3EEEB0F6F9F9E204" modified="2025-10-08" version="1">MKATGVIASLAVVASSVSGLAVGHGTAAAGYTSTAVGTGVSSTSCSSLNSTSVHHYQLHKATQLPESTKSASVNTTSSTSCSGSSSATPYTNTTSIETIATVGYATETSYITETGYAAPTGAVVNRRSNRFVNSTAPCATGTPLFPQHNVTASSILPTGTADSASSTTLLTVTRSHHHYHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJB3</accession>
    <name>A0ABR3ZJB3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Diphthine methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_000964</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Protein modification.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000013">
        <property type="protein sequence ID" value="KAL1900382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052415">
        <property type="entry name" value="Diphthine_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46042">
        <property type="entry name" value="DIPHTHINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46042:SF1">
        <property type="entry name" value="DIPHTHINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101908">
        <property type="entry name" value="Putative isomerase YbhE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00043952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="421" mass="46183" checksum="EB102AB3A5D1B87E" modified="2025-10-08" version="1">MSDLSEIVISSLKSTILELPPCCIEFSPFHPQYFVVGTYFLDKKDEAAPEQSSSTTEVREDNKLSQHRTGSVEVYYINPAKEEAVLVQTLLQPSAVLDLHFYGRPDSTGGATLCAVTSTGTVEFYRLDPISRPSEPLAHLATRSLASVSQAEGVLFLHCAWHSTESGLLAITTSDGRVMLAQVDIESYDVKACCEVPIENPLENWVVAFTPTERTADGKQAFTIFSGGDDSAMRWVSCVLSSEGIDADDGNGELSLQHPYPPAILKNQHMAGVTAILPLSRKLSDGSSLLVTGSYDDTIRVFAFRPQHEVYGMKSCRLLSETSLGGGVWRVKVMHTCPDSVTLLVSCMYAGTRVVRLLLGDGDGDGVGFEILARFEEHKSMNYGSEFVPDFYCESEDGSQKRLVISTSFYDRLMCIWHSPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJE1</accession>
    <name>A0ABR3ZJE1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tap42 interacting protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TIP41</name>
        <name evidence="3" type="ORF">Cpir12675_000704</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TIP41 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051330">
        <property type="entry name" value="Phosphatase_reg/MetRdx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007303">
        <property type="entry name" value="TIP41-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21021">
        <property type="entry name" value="GAF/PUTATIVE CYTOSKELETAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21021:SF16">
        <property type="entry name" value="TIP41-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04176">
        <property type="entry name" value="TIP41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="279" mass="31766" checksum="8E63EB72692BFBA4" modified="2025-10-08" version="1">MTTLSNPMDTKFPTPGRGSASTTIHTQGNFRISTRKLPISKAGPISEMEAKLRIPVPEMIFGDNMVAIEHVPSGWSIEFNAFDALDGVEKTAKDMLQVSYARDWSSTRETNNSHVHEVVKPYDWSYTTLYSGTFDAKSAAMMQEGKTLIPLELLKRRDPILFFEDVVLYESELDDNGISLYSVKVRVHEKRMLLLARLFMRLDNVLVRIRDTRVYVDFETDKVIREYTINEAPFDSVKQSLLRSGRLPDEITISLRDSNIIASLMKPVDGKLDEVNLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJH4</accession>
    <name>A0ABR3ZJH4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_000954</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000013">
        <property type="protein sequence ID" value="KAL1900372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01389">
        <property type="entry name" value="HMG-box_ROX1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051356">
        <property type="entry name" value="SOX/SOX-like_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45789">
        <property type="entry name" value="FI18025P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45789:SF2">
        <property type="entry name" value="FI18025P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="188"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="188"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="84"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1900372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="534" mass="57364" checksum="4CB561161F21A979" modified="2025-10-08" version="1">MIYPTQSTSSSSASTGSYSGRGASGTQSPRTRPIMVEFPPYSKYNVGGSSHVKANSSVEPAEQQYGAALYDEGRNVSAYEPTTARSNLRLYSQKSNAGRSSRPSSASSSGSCSMPAPVISGRVDKTPSPKKSGGKARSVRHDTAIQTPLSRLAAQFPNVDIADIDGFINRSSEERHVELRVGKNPGKVKRPMNAFMLYRKAYQKLAKTACSQKNHQYVSQICGDSWALEPMSVKDRFNAWAVTERVNHHAAHPEYKFSSNKVWDKRPIDGDETEVEVMDAGGNLDLNFGGTGSSSSFASSYQSQYSPYYGLPPSRFQVAPMAISATSFQSISDLRGEAAFNPMAVSQPIFAAPIAGPFLQAASESPFFGTPAESPYFGSLAESPIFTAPTGDSFLGASAEGPLVNASPGAIVGIQQAEPAMPMININRSPPLSVTEIRFNADDYPHPTSMEISVPLGTLQDEEEPMLEHFNNELGTLETANDDMEVGQELLNISRDWVSHPPIHDTLGMMNGLGQERGFSGSILDSGGNTISVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJL5</accession>
    <name>A0ABR3ZJL5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">GPI mannosyltransferase 1</fullName>
            <ecNumber evidence="13">2.4.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">GPI mannosyltransferase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">GPI14</name>
        <name evidence="14" type="ORF">Cpir12675_000893</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly. Required for cell wall integrity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Endoplasmic reticulum membrane</location>
            <topology evidence="1 13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the PIGM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="13"/>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007704">
        <property type="entry name" value="PIG-M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12886:SF0">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12886">
        <property type="entry name" value="PIG-M MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05007">
        <property type="entry name" value="Mannosyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 13 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5 13" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="94"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="176"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="301"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="331"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="368"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="398"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1900427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="443" mass="49560" checksum="11DE39DB5F28CF0B" modified="2025-10-08" version="1">MSLISGLYPSALLRTTPLFVSAAFLRATLLLYGLWQDANTPVKYTDIDYLVFTDAARFTLSPASGTPYDRETYRYTPLLAWLLLPSVAVSSNNATAIVLFAFGKVIFAAADLLAGWFLLQVLYTRGVRSARAHAYASIWLLNPMVATISTRGSSEGLLGVLTAGLLWAVSKRRFTLAALVLGFAVHFKIYPFIYAPAIVWWMEMENTAVSSSKTVQKPADLAQRVLGFVTLQRVSFAAISFATFMALNIAMYALYGYPFVLHTYLHHITRVDHRHNFSVYNTLLYLTSAEPNTTTFRIESVAFIPQLLLSTLLIPIAVAKRDLATSMMAQTFAFVTFNKVCTSQYFLWYMIFLPIYLPNSPFTTQPRLGVTALLLWIISQSLWLQQGFQLEFMGESTFVPGLWIASIIFFLVNCWILGIILADSRTSETKAMSMSLAKTKKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKM3</accession>
    <name>A0ABR3ZKM3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Calpain catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_000482</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00044">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022684">
        <property type="entry name" value="Calpain_cysteine_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183">
        <property type="entry name" value="CALPAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183:SF397">
        <property type="entry name" value="CALPAIN CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00704">
        <property type="entry name" value="CALPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00230">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="4">
        <location>
            <begin position="155"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="640"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="970"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="640"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="690"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="703"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="746"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="767"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="778"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="826"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="984"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1019"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1029"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="370"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1901251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1071" mass="120970" checksum="202F0AAE645A8BCB" modified="2025-10-08" version="1">MYNYSDSEESENPFRPRSPPFGFDPKEHKKPILNPSSPQDAINTLWKRFSVRNPAKVASVFPFDPVLPPAANEERVNEPVDASYERAKEECTRRVEKIIQECKRINTRYRDLSFDISWDLQRSIGNTLNSLGSDTFKVSSEARRNHAIRGPKAVKRISEIFQNPTFLKKISIDQAKQGALGDCWAISALTGLACVEDAVKRLCVCYDTQIGIYGFVFHRDGKWIYSIVDDRLFLTSPVWDAPSIQRDLLEQIDNNIDVEEKYNQTYHTGSKALFFASNADNNETWVPLLEKAYAKAHGDYESLDGGWIGEALEDMTGGVTTELLTGDILDTDSFWENELSRVNKDFLFGCSTGFTDGGGTGERNGIVEGHAYVVTETRVLKSGVRLVKLRNPWGTTRAGLWHGPWSDGSKEWTAEMQQEIGHTFGTDSSFWISYNDFLRKWQQIDRTRLFRDPGWYCSQHWISVDVPWKAHYHERFRFELTKNSPVVLVLSQLDYRYFRGLEGMYRFSLHFRLHKVDDPSAENYIFRSHATHLLCRSVSIDIPELERGRYSVWVMVKGDRIPNAKSVEKVISHECSNRLSNRKLEQVGLAYDLAHSRASAYMAEAARAKKMLKGKKASECRAKELRRSWELRSKLREISRKQQEKNKLKMEQRKKLALEKAKKDAHEDEDSASSSSEMKRSEKKSAGPSKTKHCRHCRFYKSKQAEKLGESDSERSKTCNVEKAEKESSSRAKTARAPQDSGVAEEAQHEAKNAKEVSDSEDPKPAKSNKGRSRRKGASSSKTHANAAASISESRSSSKPTDTDTESETDQQSTKARKYCRCAKTYSKNPASQSPCETSKTSEARVEESSDSPISDWDELYSSSDYTRRPRASPASKIPRSFFEVPEDPKTPESWNAICIVGFRVYSKDRRLSMGVVVPNGEEWGWARGECDLDNAQMNAGGERIAGTDKEEEVVKVVKIDTNVKEIDAIDMRRRGSQNSEESILDKPTESPSKSPEERPANNGPAKELPAPQLIAQGEGEDGDDEGGRDENCSESERSREKHKSTPTKRSESESSTDDGVLTPSSDQSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKR0</accession>
    <name>A0ABR3ZKR0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Fe(2+) transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">MRS4</name>
        <name evidence="12" type="ORF">Cpir12675_000985</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000013">
        <property type="protein sequence ID" value="KAL1900403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45758:SF4">
        <property type="entry name" value="MITOFERRIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45758">
        <property type="entry name" value="MITOFERRIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="24"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="121"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="214"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1900403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="313" mass="33983" checksum="927E4984E2699846" modified="2025-10-08" version="1">MSQSDALKHVEEDEYDYEALPPNFSLGQNMLAGAFAGIAEHTVMYPIDAIKTRMQVLSPKPSAVYNGVVEGTYRIASTEGVLSLWRGMTSVVVGAGPAHAVYFATYEAVKHIMGGNEAGVHHPLAAATSGACATIASDALMNPFDVIKQRMQMHNSRQMYRSIFDCARYVYRKEGIAAFYVSYPTTLSMTVPFTALQFLAYESISTAMNPSKKYDPLIHCTAGAVAGGFASALTTPMDVIKTMLQTRGTATDAELRSVNGFIAGCKLLFAREGAKGFFKGMGPRILTTMPSTAICWSAYEFSKSYFVNRNDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLL3</accession>
    <name>A0ABR3ZLL3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">glucan 1,3-beta-glucosidase</fullName>
            <ecNumber evidence="10">3.2.1.58</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Exo-1,3-beta-glucanase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">BGL2</name>
        <name evidence="14" type="ORF">Cpir12675_000854</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>Successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1-&gt;3)-beta-D-glucans, releasing alpha-glucose.</text>
            <dbReference type="EC" id="3.2.1.58"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the glycosyl hydrolase 17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.58" evidence="10"/>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004338">
        <property type="term" value="F:glucan exo-1,3-beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050732">
        <property type="entry name" value="Beta-glucan_modifiers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000490">
        <property type="entry name" value="Glyco_hydro_17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631:SF26">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00332">
        <property type="entry name" value="Glyco_hydro_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0134">Cell wall</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047013476" description="glucan 1,3-beta-glucosidase" evidence="13">
        <location>
            <begin position="21"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00036824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1900718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="301" mass="32314" checksum="00420B3B2CA1024D" modified="2025-10-08" version="1">MHFTSTVAAGLALVPSLVSAAGSLGFSLGAVNPDNSCKSQATYEADFDAILAASGSRLVRVYAAGQCDTAKNILPAAKAKGFQVVLGIWAFPEDSYNLDKNAILQYGPGYEEQIYAVAVGSETLYRKEFTGPQLAAKIKDFKQSAPQYKVGTADSWNKFNDGTGDAVMSEADIIFANAFSYWQGQDINNAADVFFDSIMQAFNHIQSISGSLSKPELWVGETGWPSKGTKYQQAVPSVENAARFFEEGICAMVDSGFNVFAFEAFDEPNKAAAVGDDGSVADETSWGVMHADLSRKYNIQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLS1</accession>
    <name>A0ABR3ZLS1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Proteasome regulatory particle subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RPN7</name>
        <name evidence="3" type="ORF">Cpir12675_000346</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019585">
        <property type="entry name" value="Rpn7/CSN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045135">
        <property type="entry name" value="Rpn7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049549">
        <property type="entry name" value="RPN7_PSMD6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14145:SF1">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14145">
        <property type="entry name" value="26S PROTESOME SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10602">
        <property type="entry name" value="RPN7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21154">
        <property type="entry name" value="RPN7_PSMD6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0647">Proteasome</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="2">
        <location>
            <begin position="233"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="485" mass="53753" checksum="3C3D200F0D39397F" modified="2025-10-08" version="1">MSSEAQYAQWPQLALSQHIFNLTNSYASRTTQQASAKAVQDAIAEHKMAPLYRYLAHPTEGALYAAADESVLGSSLSGKPSLTRKSSLLGMIAGKSSTASAYLPWDESLYVKLKSENDAELEGYKNEEEEAVEKAGDIEIVAASGKRAEFWARVGDKDRAIAAYEEVIEKTGMLGTKIDIVLAIIRMGLFFGDKALVKKHVSRAKTLVESGGDWDRRNRLKAYEGVHLLTVRSHNLAAPYLLDSLETFTSYELCSYSSLVTYSVLAGAVSLKRVDFKSKVVDAPQVKAVMGDGEDRLMALSLDEKTPVTGTHGSASKRGVVNLATLNSGEEIETETTTDFSALATLVSALYTGNYKAFFQSLAQVEEQFLNQDRYLLEHKNWFIREMRLRAYQQLLQSYRVVGLETMAHDFGVTVEFLDRDLAKFIAAGRIPCTIDRVNGKGVIETNRPDTKNKQYQDVVRQGDHLITKLQKYGQAVRLRGSERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMV6</accession>
    <name>A0ABR3ZMV6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS12</name>
        <name evidence="6" type="ORF">Cpir12675_000720</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000530">
        <property type="entry name" value="Ribosomal_eS12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047860">
        <property type="entry name" value="Ribosomal_eS12_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11843">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00972">
        <property type="entry name" value="RIBSOMALS12E"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01189">
        <property type="entry name" value="RIBOSOMAL_S12E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="5">
        <location>
            <begin position="53"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1900844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="168" mass="18665" checksum="783B02ED3C2F8C4E" modified="2025-10-08" version="1">MTIYGDGTIQRFDFTIFLQGPIKPRSDVEDNTAQEVEVSADAATKGQITVLEALKGVLKLSLMHDGLARGLREASKALDRRQAHMCVLNEACEEEAYKKLVIALCSEHNIPLIKVPDGKELGEWAGLCVLDREGNARKVVNCSCVVVKDWGEESQERSILLNYFQSEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMV9</accession>
    <name>A0ABR3ZMV9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome P450 94A1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_000123</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="501" mass="55140" checksum="2E03590B81F8DFEF" modified="2025-10-08" version="1">MALLQIIPPSAIWAALITGACLTLYSIFNSPSIKRHGQPLRRAPNTLPLIGNGILFLQDRFALFHWFTRCEQQYSYETLQVSVPTLPSGVVVSSPANVEFVLKNVGLFSKGSFFKERSWDLFGHGIINVDGELWRLQRRAGLSFLNAANLKALTEVELPRILDASLAELRQNAHDTSIVDLQEFFHEITTQLMGHMAYGMEMHTGDDFTQAFEYASGVTAERVQNPLWKLTELFNGGRMRASIAAVHQYGREIVATAVAARHKASMRGSGSISGASLIHSLLDSIGNEKIVADAALNYLSAGRDTTAQALTWVFFLLAQNPDVVSCLRAEISALTGPPIIQDLPYTLAVFYETLRLYPPVPFEIKQAEEATTLPDGSFLPAKSIVLWCPWAMNRSFTTWGLNAEKFQPSRWLTLDEKGIPRVLNRSAAEFPVFNGGPRTCLGKKMAEVVAVRVIAEVIRGFDIHLCCSTDRRSGSSLTLPMEGGLPCQVSLCNDKVPPGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMW9</accession>
    <name>A0ABR3ZMW9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">26S proteasome subunit rpt4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RPT4</name>
        <name evidence="8" type="ORF">Cpir12675_000138</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 8" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="7">
        <location>
            <begin position="168"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="14"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1902033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="391" mass="43875" checksum="CADD630C6A0EEA97" modified="2025-10-08" version="1">MSDEAERQRALASYREKLIESREWEAKLKNLRLEIKDLVKDYDRTEENIKALQSVGQIIGEVLKQLDEERFIVKASSGPRYVVGCRSKVDKTKLKQGTRVALDMTTLTIMRMLPREVDPLVYNMSLEDPGQVSFAGIGGLNEQIRELREVIELPLKNPELFLRVGIKPPKGVLLYGPPGTGKTLLARAVASSLETNFLKVVSSAIVDKYIGESARLIREMFGYAKEHEPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQLDGFDYLGQTKIIMATNRPDTLDPALLRAGRLDRKIEIALPNEVGRLEILKIHASSVVLEGEIDFESVVKMSDGLNGADLRNVVTEAGLFALKADRESINQDDFARAVRKVAEAKKLEGKLEYQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN23</accession>
    <name>A0ABR3ZN23_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA polymerase delta small subunit Cdc1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">cdc1</name>
        <name evidence="6" type="ORF">Cpir12675_000431</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA polymerase delta/II small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007185">
        <property type="entry name" value="DNA_pol_a/d/e_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040663">
        <property type="entry name" value="DNA_pol_D_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024826">
        <property type="entry name" value="DNA_pol_delta/II_ssu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10416">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10416:SF0">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18018">
        <property type="entry name" value="DNA_pol_D_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04042">
        <property type="entry name" value="DNA_pol_E_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA polymerase delta subunit OB-fold" evidence="5">
        <location>
            <begin position="47"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="DNA polymerase alpha/delta/epsilon subunit B" evidence="4">
        <location>
            <begin position="228"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="192"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="210"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF18018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1901562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="504" mass="55818" checksum="6ECB460CEFC73FB0" modified="2025-10-08" version="1">MVTLDQVTSSLLSAPSKTTPPSQSRIASSYHPLRSFDLPQVRSYQQQYGDMYFLRLTKIKPQVEEIARDAWEGNVIAGEIVKKVERVLDVRQGELCWVTGTVYMDMALKPNILEDVSKDRWVVGPPVTQKYYSEDGSDQIMLEDESGRILLVGKALDSVLLVTGCIISVMGTETANGELDVIDIKFPDLPPQPKRWTFDKPPTGNRDTEQGNSMAPANSPSKKGSKLAIVSGLSFSGNDASYALELNLLLEFLLGESGDPALQSNLASVSRLIIAGNSIANDEPKEKLTEDKEKKPAVKKYGYDSSTYNPVPSQLFDRFLFDLLPSMPITVLPGPKDPANVAYPQQPIHTAMFPLSRQYAAEPTKDGAKTGWLDTVSNPWEAEIDGWRVLGTAGQNVDDVFKYVGSDDRLGMMEAMCRWRCIAPTAPDTLYSYPFHDNDPFVIKDCPHLFFVGCQPSLSTRVIEGSDGQRVRLVTIPSFSKTHEICLIDMETLEVTKVKINVHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN78</accession>
    <name>A0ABR3ZN78_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NRC2</name>
        <name evidence="10" type="ORF">Cpir12675_000053</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05574">
        <property type="entry name" value="STKc_phototropin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45637">
        <property type="entry name" value="FLIPPASE KINASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="252"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="576"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1902153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="652" mass="71294" checksum="CA0E422B7C2745D2" modified="2025-10-08" version="1">MPSAKTTNGNGQFPQKIRNFFRINHNGSNTSSTDKLVHDAPATKTDTSPLPLSKSTFRHTKFFTMGRLRSHTVAGEGNPIEEAMSPTAHANPYFAHQGQPGLRHHNEGSVPPSPPDTPELKIVGPEGADSIVDEQGTAANKEELARKLRRVASAPNAHGMFQNGTADRPATAQMGKDPLMVDGNFVGFPDSEAQLSGSLPTSSTSDSLSVPDADELGALPTAPARLIAAGFRRTYSSNSIKVRDVEVGPQSFDKIKLIGKGDVGKVYLVREKKSNRLYAMKVLSKKEMIKRNKIKRALAEQEILATSNHPFIVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRPGKCIPEEDARFYAAEVTAALEYLHLMGFIYRDLKPENILLHQSGHIMLSDFDLSKQSDTGGKPTMIVGKNGTSTTSLPTIDTKSCIANFRTNSFVGTEEYIAPEVIKGSGHTSAVDWWTLGILIYEMLYGTTPFKGKNRNATFANILREDIPFPDHSGSPQISNLCKSLIRKLLIKDENRRLGARAGASDIKVHPFFRTTQWALIRHMKPPIIPNQGRGVDTINFRNVKESESVDISGSRPMPGATAKPKSDGSGSGLGTSDSGELGPGTPGAEIVDPFEEFNSITLHHDGDNDMPLNMNEHLKGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZND3</accession>
    <name>A0ABR3ZND3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000357</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="280" mass="31318" checksum="0FD61E5B4CF07835" modified="2025-10-08" version="1">MVAASKKGKANVSTKEPKGPTTNPIDSTKNESQCQYQIPANDDEASKHLQEFISEADQPDVLNFAYKAQMLHQGQRIGENIDQMKTTLANIESTEAYTASQLSSLTAYEEDAQEKLSSRLDDIGSTVRNTSNDVKSFQSIMTEFGTTMSKIELLESQIANSVSEKLTSHLETFTAEAREPEQRLSTELLSHLKETYAKISSLSDTMGNMEMKTNTLNSRLEAVLETIPKELQSLRHTLKETNTHQLLQTENKAEPKEKQTPQNCMSAYKYLPSLNSLTNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNL7</accession>
    <name>A0ABR3ZNL7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glutaredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000262</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03419">
        <property type="entry name" value="GRX_GRXh_1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011899">
        <property type="entry name" value="Glutaredoxin_euk/vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014025">
        <property type="entry name" value="Glutaredoxin_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02180">
        <property type="entry name" value="GRX_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694">
        <property type="entry name" value="GLUTAREDOXIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694:SF5">
        <property type="entry name" value="GLUTAREDOXIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00160">
        <property type="entry name" value="GLUTAREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="2">
        <location>
            <begin position="215"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="340" mass="36795" checksum="1C1FB4E3C12FF331" modified="2025-10-08" version="1">MTKMRSSQRRFRSYIVIALVVFAIYYLSPSHSDPQDFYRKTMQAMGSHNGGSGSTRAGSYASSVAASAQGPQHPPIPDALDHKEITDDADAKVVKEMSNRVKDAAARAKDAANKKSPLKPDLPSEVVGVGSSAGGQNGKDKEKEIAKEAATHKTDKETVMSGAQLQDQKELGGDGKAIGKTSAATSSHKEETEETPLQHEAELELTSILKRAPMIIFSKSYCPYSKRAKKLLLETYTLDPEPYVVELDDHPLGSEIQDLLAEKTGRRTVPNIMVNGISIGGSDDVVALDTAGELVSKVLELSSARKLSMVATADKAKTQKTETVPSKNIPVRRSIRVKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPP9</accession>
    <name>A0ABR3ZPP9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_000030</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051176">
        <property type="entry name" value="Cent_Immune-Sig_Mod"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15715">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 170 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15715:SF46">
        <property type="entry name" value="TO VACUOLE TARGETING VPS64, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02420)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="829"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="4">
        <location>
            <begin position="259"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="175"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="398"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="478"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="688"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="558"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="47"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="79"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="175"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="189"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="507"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="536"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="692"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="712"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="757"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="774"/>
            <end position="787"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1902132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="859" mass="92572" checksum="CD05791962C3BC18" modified="2025-10-08" version="1">MTAVAAPPAFSPLNNQQQQPQQQPHHQPWSANNLSGSAAKSSVVMKPESSPDSDAPLASSPSPPEDPLRLFPRKSLQRSNSSSSISSTSSASSASSTTTVATTGSSPGTPASSTGEPVPLSINTAFKKLPQTAAGSHDQLLSHRAPHKKIWLHARSEPAVEQPSTNNTIATRPLASQESTSAQTAALHAQQQMPTAPPLNTNGQQAAQSQQLASNSTSQSASAAASEDNEPIKVLLYLISLNNTFERKTIHVPMRPAVLRIGRQTNQKTVPTPTNGYFDSKVLSRQHAEIWSDRSGKIWIRDVKSSNGTFVNNVRLSAENLDSDPHEIKTGDHLELGIDIIGEDGKTIIHHKVSAKVEHAGPAGAGTGPGSLNNSMDFAFNELDPAASLLMSGNGSPAIQGRPRNGSNPALGPNGRSMTGSGPVGGPMAYPRPFMLTPITTENIIKRLQNEIRGARLQNHDIERSETFINTLVTKDLLAPADPPTKPPITNGYHSFRADSKTRFSDPPAPPPQQPLPEKPTDVPSWKKSPSERSKSQSNNHTSSREPSGQAFYMQTEIDNYKKKLNDQEVRLKVLEETLHSERSARQAAEDLNQKLEEAMSSNHINSIDKERQAFEAKAAASANDEAKVEVQELQSANLALKALIETLRKEMETTSQMWERRLQKAEAEREIAQKSLAEMVLRIREESSARNRNKSSQHHHHRQHGVRSRSARSSSSSSSGSSDPSSDEASASRSSSKRVTKSLLVSTPQAHADSSSSEDESSEDDDSQPLVRKNQQTAATYKHSTTYKPRLATSASAAMASATVGADGKSTTSSRQQHSRGQALAKSLPYASVVGVVILGVGVMAFINGWQPQPRVEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YCN8</accession>
    <name>A0ABR3YCN8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="4">3.2.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Endo-1,3-beta-glucanase btgC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Laminarinase btgC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Cpir12675_006868</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Active on laminarin and lichenan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000398">
        <property type="protein sequence ID" value="KAL1886074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050732">
        <property type="entry name" value="Beta-glucan_modifiers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631:SF17">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-GLUCOSIDASE BTGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="231"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="259"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="13"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="261"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00042373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00043078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1886074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="602" mass="64591" checksum="DFEDA13134E984B9" modified="2025-10-08" version="1">MPANGLMPGVPASASASNRNSQISSSSTSTYNSSSHSSPNPDYSLQTTSGQPPSPVLGPEVPLHRDFDVNTPLPVIRSLGSSSRSRSRSGSSLRDPFQDDHFQNYASSRGLDPRLGEVNPHMIADDGDDGLVYGKPGRNSLINVHRKSARSVSPNIKAAAAMGGAVMLNTLPGGGSPNQSGTGLAADAPTPHDSTYKVGTAAAAVGFSPDGLTEKGRNAPSIKNSNRRRKLCIIITLGVLLLAGIIGGTLGGYLGNRNKKGSSSDSDNGQSASQDTESNGVLTKDSTEIKKLLNNANLHKVFPGMDYTPINTQYPDCLHNPPSQNNITRDIAVLSQLTNVIRLYGTDCNQTEMVLEAMKNLDVSSSMSLWMGVWQDSNTTTNERQLSQMWDVLDNYGTTPFRGLVVANEILFREEMTETELGNLMAEVRTNLTDRGFDALPVCTSDLGDKWTSSLADKSDVIMSNIHPFFGGVPYAEAANWTWSFFNTKNADFFKADAADNIISEIGWPTSGGTNCPADATDCGSTGSVASIDGLNALLDDWVCAAMENGTNYFWFSAFDEPWKVRFNEEGAEWEDQWGLMDVNRNLKEGVVIPDCGGETVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YDV7</accession>
    <name>A0ABR3YDV7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein alcS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_006951</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000448">
        <property type="protein sequence ID" value="KAL1885997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051633">
        <property type="entry name" value="AceTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123:SF4">
        <property type="entry name" value="PROTEIN ALCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1885997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="314" mass="34099" checksum="5ABBC7B3EAC8236E" modified="2025-10-08" version="1">MHPHSHSSHENLSDKPTVENHENMDHIDHNNVAKTTGIAHPNGNIPRIINNANGNPLEHQRTYGSINISPEMFEELYLAPKNRVAGQLRQTYGNPTPVAIGGFVLTTTPLSMALLGWQGAGGLVAPANVGTYLWLGGLLLLLGGVGEWLLGNTFPCTVFMTFGGFWLTVGTTLVPEYGAYTSYATDPSNPASGAANPMFFATFGFFLVCMTILSFVFMIASMRVNISFFMVFFTLVFTFACLTGSFFRAAQGHSDLSLKLQHVGAGFLFATSMFGWWIFFGLVLSSVDFPISLPMGDLSTVFKGKADRAKTNMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGK1</accession>
    <name>A0ABR3YGK1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Endothelin-converting enzyme 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_006541</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000318">
        <property type="protein sequence ID" value="KAL1887446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08662">
        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="entry name" value="Neutral endopeptidase , domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733:SF167">
        <property type="entry name" value="FI17812P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00786">
        <property type="entry name" value="NEPRILYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046974197" description="Endothelin-converting enzyme 1" evidence="8">
        <location>
            <begin position="19"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 N-terminal" evidence="10">
        <location>
            <begin position="65"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 C-terminal" evidence="9">
        <location>
            <begin position="499"/>
            <end position="701"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1887446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="708" mass="78770" checksum="218BC4260E2CAF3B" modified="2025-10-08" version="1">MRFSSVLAPSLLAHAINAQSESASSTADHEAAPTSNPGYCNTPACQRLATDLFSNLASNYADLDPCSRFEEIACGGWRLKHDFKPDQDTVATDILIQDHINEVMREIVEGPLPAGIDPSSQDAKNFYKMKAIYDACMDVDTIKSLGIEPLKKVLAEMDGARSIKEALLILLTNDVTGLATVGPEIDDIDPDYVAVALTGPMDFGMPSPLGFKSKKLLVGYYRVVEEVLPALYPETTKETILELVRLERDIAILLPPPNARSNLRELYNPMTLEEANALLPALGIQDIINTLAPQGVPIERVIVHHPNYFSALPRILRNVQPETLKAYFRWRLITSYEPFLDDDTLKPLKGLRDLFETQDSRQVQCVAYVDRSVTGIISRFFVEKAFSPAAKDLAKEIVANLKNVYVEKLKTSQWMDEYSTERAIKKVLNMKEKIGYPTASPNITDPDDLAHMYRNSVVDDKTYFENEVSLRHMRSKGQWESVGKPADHDAWQYTPNEANAHYVAPGNNLVLPAGLMQYPALDVDVPAYISYGAYGSIVGHEISHAFDSNGHLYDENGAFSETSDWWTPNTEAAFSARTQCFVDQYSSLVNEVPNGDVKIKHYVNGENSLDENIADTGGLSASYLAWKKLDDEGKGGEMLPGLDIFTRDQLFFLSFANYHCSKLQAPDGHIFDNVHSPGWARITGSLANSEDFLRAFNCPAKESTCKIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGN7</accession>
    <name>A0ABR3YGN7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Rho-type gtpase-activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RGA2</name>
        <name evidence="9" type="ORF">Cpir12675_006531</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000316">
        <property type="protein sequence ID" value="KAL1887476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09394">
        <property type="entry name" value="LIM1_Rga"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09395">
        <property type="entry name" value="LIM2_Rga"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00159">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050729">
        <property type="entry name" value="Rho-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176:SF128">
        <property type="entry name" value="RHO GTPASE-ACTIVATING PROTEIN RGD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176">
        <property type="entry name" value="RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="4" id="KW-0440">LIM domain</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="7">
        <location>
            <begin position="24"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="8">
        <location>
            <begin position="991"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="144"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="224"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="297"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="585"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="947"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="648"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="233"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="245"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="331"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="345"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="357"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="370"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="388"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="430"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="465"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="486"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="508"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="527"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="585"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="952"/>
            <end position="962"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1887476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1180" mass="128340" checksum="6B18886C45438EEF" modified="2025-10-08" version="1">MAATETAVPAAPGMEDYMEPDEIFSCTRCGEILEEGKAYELSGLRWHINCFRCNTCDVLLDSDANLHLLGDRSLICSTCTYSCSACGVKIEDLAILTGDQAFCATCFRCRNCKRKIENLRYARTSVGIFCMTCQDTMTARRKKKAKAARAAKQREKDGTGSPMITEKSLPALPPAIEKRHDAQPDAATELSPRPRQHYTNHISDVLNGASATVADRAISESPVNQKNDILLPSTTYGSSNTNSTVPTNRSSTLPDGSVDLDSFFTPMSLDPSVSAPPARPTTSTSLAPHIFFQEKGRLPSGASESSSLISQQQSNTSSVATAPTRKPSKSSRSDARSSHYEERSNYSPPRSNTGAADEFKLQDAPKSKKLSSSPISQSSDMANFAGLTNNINSSSKSSSYATSNTTSRVSQDDGLRPDPNSKYLARKDVPSNSTVRSSLNKPNPITRTSSDTAPARPIHNEAALSHTTAATPSSNTKLSNTYTQPRPAPAPPVAPREPSTTLQSGLTPPNPPTQAPPVPGAGAGASRNGSKQSNNGISTSPTLPIWSSGAEFTLDEDMARIMGNDEGSSILRRVSNAVRHGRTNSTEMNITGSSRPSHTRSISETTRSAVVASGQWPKTPTKESNGLLHNAHDIQSPGSLVVSPNDDAAFLKRQLRSSELRVAELERQADTEKNLHALTQKLTEKRKTVAELDTQTELMIRQVEVLAGYADRAKQTSMTVNIRELEDLAIADFIDRLEQVKISMSDQIEKLYAERSLLLEEKEHAVAERDRALMEFEQLSSKNAQLADMNNDLTHQIQERFKAQINMDPKSPNGLGIYGASKLTGDGSSIHTGTTLLCGDNEDTIVEAGGPMVVNIRKGQVKKFNWKKGSKTLAQNVGKGVSKAAAAFQNDKERAAAGQPGFLAGDNIGMPYNMTVAQVDAPVTTGNPNGRKDVHLEQQRQGFGFFKKSGQAGPGANNGGNNGNNLQIGKSMSGSVSTPAVAEAPSTLFGSDLTERADYERRQIPCVVTRCIEEVELRGMDVEGIYRKTGGNSQVKMVQDGFDKDENYDISDPVIDITAVTSVLKQYFRKLPTPLLTFDIYNRILESNAISDPMERCSHLSRTFRSMPQRHQDTLEFLMFHLIRVAKREPENLMSPKNLAVVFAPTIMRDTSIEREMTDMHAKNIAVQFVIENSEIIFSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI54</accession>
    <name>A0ABR3YI54_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_006342</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000284">
        <property type="protein sequence ID" value="KAL1888008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="376"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="509" mass="56927" checksum="38BC05BF82F2EF39" modified="2025-10-08" version="1" fragment="single">AVLAMTKANIETLPTLLTTYHTPGYLTECKIWEAARATSAAITLFDPIKLGRDEIQFVDASHGYNNPCEALIWEAERQFPGRPIMTLSIGAGLGDVVEISDSRDSICNSDEAQLCKHIIANVLVTYRPVTWDELNVLVEAFDGLEKEDVKQAVSLCGSFLTVHKNVVSFVHQSAKDYFLEKATGEILPLGIPHQHQTIFLRSLDILQKELRRDIYSLAAPGCLIEEVSVPKPDPLAAIGYSCFFWVDHLNDSSSNGMVTKNDEILAFLNEKYLQWLEALSLLKVISIAGRRMEKLKSYSQEKKAPQDLRVLVHDAYRSLLLHKGIIEVVPLQIYISALIFSPTNSLIRRVFSREEPDWIELKPEVEANWCACLRTLKGHGNSVTSVVFSNDGQQLASGSDDKTVKIWDATSGACLQSLEGYSDDVTSAVFSTSVRRPISPLLVDQPTSRHTELDHYCISSDHVWVLQDQQRLIWLPPSYRPVESAISRQAVGFSTSSRRIIVIRFRSIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI61</accession>
    <name>A0ABR3YI61_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006497</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000310">
        <property type="protein sequence ID" value="KAL1887562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="101"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="220"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="296"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="522"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="593"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="730" mass="79360" checksum="0308F39E7763DB0E" modified="2025-10-08" version="1">MSVYTGSPYSAWARAVSEVQAEADVNAESSFVFSVNSTHSVVFFSEFIISGAKSVRSATMILASFNILTAFITVVGILLTSWVRSRRRAAGIAVPYVGSSFVCLPELFPLVLSVGITIQATIFVISQSLGLKSPTVLGCTVTSQVMFPAVFIVPYIQMVFAINEAYMALRSSPFSKRGTWNFIICIMAVFLLLLIKYIVALVIRPPNFCFAFLYWFVLRWGLACFIISVVVLLSLVISTVIVFYKLRLTSNADPEEQATAATMVYYMVIGILTNFLFVPFFYSIGVQGSRSSNDTAVQLSLVSSIVSNISGILTGGLHLYLRSKLTTTMPASNGADGGGFNKNKDKSQKDTLQSDPKDEWDYVMGKPVALKKKGPPRRPVDSLKFNKLPSVSGHWKTNSMPQKPDPVKMLPPIPNDVPGILKRSSTRSSKPQSRYSSKTRSASVAATETTDLLPSTTYDPRLEKTSMPLAATNARKSLPKITEPSHGKEVSVARNLQATMMPFASNAVGSKASLLVPPAAYGNTSGKSTEKPRHGRNSSLGSLNTTATVQIGLRLSNVDGMRLNSEYFHDSNEVYSINYDILSPGMRANMLSPRPTKPASQQAKPSGALINPFSPGLVSPQQSPQRGEYSSRYPSTISNMMGFSFMDINSPGTGTSIETRLQSPVSPIAPLNLAMLNSMVYDPYNAGQAASRYRERDSQGVSPISPVESSIQIRLLASPRTAAQAQKDWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ73</accession>
    <name>A0ABR3YJ73_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">High affinity Ca2+/Mn2+ P-type ATPase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PMR1</name>
        <name evidence="11" type="ORF">Cpir12675_006302</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000279">
        <property type="protein sequence ID" value="KAL1888080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08282">
        <property type="entry name" value="Hydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="855"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="890"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="926"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="956"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="10">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="116"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1888080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="996" mass="107908" checksum="AB75E41922E5EFB4" modified="2025-10-08" version="1">MTPAEAAHQLSTSLTHGLSINDALKRLTEYGPNEIPHEEPEPIWLRFLRQFQEPLILLLLVSAAASLLLGNTDDALSIAIAVTIVISVGFVQEYRSEKSIEALNHLVPNHAHLIRSGPNPSHKSSATATWPPLEPGPDENGEKITTPGEEILEATSTKVMASQLVPGDLVLFTTGDRIPADVRVTKASDLTIDASNLTGETEPVRIVVEARVPNKLLHTNNLVPPPSPSSAHDEGDGSNIAYMGTLVKSGYGQGIVFATGGATNFGAVATSVSGTESPRSPLQLSMDDLGSQLSKVSFVIIGLISFVGWLQGKNLLDIFTISISLAVAAIPEGLPIIVTVTLALGVHRMARHNAIVRRMPKVETLGSVNVVCTDKTGTLTTNHMTATRVWFFGAANAIDVDKEVDSTEVQPDNATLRLIRIGTLANNARLARQFAEGGDNANRARAVLSSTDDEKHISTLTRWVGLPTDVAMMDLMDRFKELDARDTLGPPVSEMPFSSSRKWMGVIMGDQHNDKEFAYMKGSIDKVLEACDTYFDSECRQVSFDAQTRQQAMEAADAMASQGLRVLAFASGPVPRTFRGSRSRSGTPLDNVPLSSGYDNAYKELTFTGLVGMRDPPRSGVSNSIRKLLRGGVKVIMITGDSEATALAIGRQLGMSIASVQEATPGQIAVHPVLRGEDVDKMSEEVLAEAMQNTTIFARTNPDHKLKIIKALQRRGDIVAMTGDGVNDAPALKRADIGIAMGRNGTDVAKEAADMILTDDDFSTILHAIEEGKGIFSNIQNFLTFQLSTSAASLALVFFCTCLGFKNPLNAMQILWINIIMDGPPAQSLGVEAVEKDVMSKPPRRRSDPVLTQAVLTRVLTSAAVIMFGTMMIYYREMLADGEITRRDTTMTFTCFVLFDMFNALGCRSSTKSILRGEVGLFSNSLFNWAVSLSLIGQLLVIYFPFFQEVFQTEALGLGDLITLIMLCSTVFWVDELCKYIKYDVKRLGSGYSQAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJT5</accession>
    <name>A0ABR3YJT5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nucleoporin NUP53</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000257">
        <property type="protein sequence ID" value="KAL1888511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="107"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="511" mass="55122" checksum="7BB541917342342B" modified="2025-10-08" version="1">MAPLILHNVPDEELYVGVDGIQRPYAMVFSQQEGGMPPTRNRRAVAETGSFGKSNRRSRSRTGTPRRERDNPTQAVADKIFGDWVSMQAAAPNNTNSNSATGGGSGSAASGPSSNSAPRRPSSLAKTVSHSALLDLDDVTMGGTSTATHHHHRHHQNQTQNHGEPVELMLRGYRNSTQQYAAIAHFEQLAGRICEDYPRMAPMEQRRYRSELTDPAFTQRRALTSDERAKVNMAAGGEHWVKVTFESAEAAEAARMASPQNIMGYLVSAELWTGVAPPKDEAVPDLSNLFDPPARNKSIPGLQSTANPFLKRATSNSAFPRSTTTTMGDGADEASPSYSHTSSNTFDSGTNTLDGGEQAFASGSAASQISQIAMRRHSMGVPASSFAPTVFDDDDVAMAGATDVHGNISGNDATGAGTNGAYCRRIPTARRVQILPAEQALLPQQSMAQRVVAAVPFLNWFGGSMVGSAVPRSELGEFDWVRASLYWKVVWFLDAWFGLFGGEIFRGNREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKA6</accession>
    <name>A0ABR3YKA6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Mediator of RNA polymerase II transcription subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">MED7</name>
        <name evidence="12" type="ORF">Cpir12675_006053</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the Mediator complex subunit 7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000246">
        <property type="protein sequence ID" value="KAL1888756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037212">
        <property type="entry name" value="Med7/Med21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009244">
        <property type="entry name" value="Mediatior_Med7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044888">
        <property type="entry name" value="Mediatior_Med7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21428">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21428:SF11">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05983">
        <property type="entry name" value="Med7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140718">
        <property type="entry name" value="Mediator hinge subcomplex-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0010">Activator</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 10" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1888756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="256" mass="29119" checksum="372E4EDF8DB198C8" modified="2025-10-08" version="1">MADSQDPNQSRTALAGQLPDPPPFWKSFTDQNMARIKKLQEAMPAAHPNGSSLLMRLEGLSPDLLYLQPPAEPPNGEWRVFGNKYTLDDKLPSLEEQGMDRLVPKQEDDANSKDIKHLDRAFELKRLAKSVLLNFLELMGQLSIDPKFAEAKVSDIRTLFINFHHVLNEYRPHQAREQAISLMQDRLDKIRAETTAINAQMDKAKRVLDGLASIDVPNVETAMAEMSPVRVDKEEALKQRDTEIWQHADMLLGLEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLB6</accession>
    <name>A0ABR3YLB6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Histone acetyltransferase</fullName>
            <ecNumber evidence="3 12">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">SAS3</name>
        <name evidence="15" type="ORF">Cpir12675_006003</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4, H3, H2B, H2A and H2A variant H2A.Z. Acetylates histone H4 to form H4K5ac, H4K8ac, H4K12ac and H4K16ac, histone H3 to form H3K14ac, and histone H2A to form H2AK4ac and H2AK7ac. The NuA4 complex is involved in the DNA damage response and is required for chromosome segregation. The NuA4 complex plays a direct role in repair of DNA double-strand breaks (DSBs) through homologous recombination. Recruitment to promoters depends on H3K4me. Also acetylates non-histone proteins. In addition to protein acetyltransferase, can use different acyl-CoA substrates, such as 2-hydroxyisobutanoyl-CoA (2-hydroxyisobutyryl-CoA) or (2E)-butenoyl-CoA (crotonyl-CoA), and is able to mediate protein 2-hydroxyisobutyrylation and crotonylation, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17 18">
            <text>L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:45948"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the MYST (SAS/MOZ) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3 12"/>
    <dbReference type="EMBL" id="JAWDJO010000240">
        <property type="protein sequence ID" value="KAL1888914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061733">
        <property type="term" value="F:protein-lysine-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.60">
        <property type="entry name" value="N-acetyl transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002717">
        <property type="entry name" value="HAT_MYST-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050603">
        <property type="entry name" value="MYST_HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040706">
        <property type="entry name" value="Zf-MYST"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615:SF161">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE KAT7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01853">
        <property type="entry name" value="MOZ_SAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17772">
        <property type="entry name" value="zf-MYST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51726">
        <property type="entry name" value="MYST_HAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0007">Acetylation</keyword>
    <keyword evidence="15" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYST-type HAT" evidence="14">
        <location>
            <begin position="533"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="243"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="829"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="974"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="32"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="79"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="249"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="981"/>
            <end position="995"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1888914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1058" mass="119279" checksum="B3E87CFEB1C4314D" modified="2025-10-08" version="1">MAHPAILTEEDLQKSAALSELSPSPETPSIDTRSENESHHGEREEGGDEYEDVGEDEDGDDDAEDKDGNENEHSSENSGEYDEVEDDGAEYDEDEDDKAEDDDGEDEDDKAEDDDSDEDEEDNENDDNEDEYDEDDDEEEYDEDDDEEESEVEVGTSNYFKASNHHRIPSNPHEPKSPKNATPTLLGEDARHVSKCGSSEKHNDGGFRAIGLQLNTNKGVANDVDFDSSNDSDSSYGQSFATLEKANAEEDSDENEDDSDGTRRAQQSCIQEFSPNAIGNNNFSNWTCRDCHDSDQTTSLTLPHPSHDAVSEAAFSELEHQSTLTENFRNTDENARSLRKRTLTTRDEDEAAPIFRKRLRQNPAMSRRSLDNIEKDFERLPSTRSLRMKKHRHVVVTPNGPESLLVTMHVKPSALNLVLSQAPAGYSYEGRGRKRLVPLSTSSTITEPPPAPFTHMSQPFYSFFDRDINEVNGKPYGGILTDLEADTSKTLPTDEDRKRFAEAKSTAEIEWRDRVLRMQSENPAPAKKSKKSRCGSQIECIDFGGWEIDTWYPASYPEEYTRNRVLYICEFCLKYMNSDYVAWRHKLKCPAKHPPGDEIYRHELISVFEVDGRKHPVYCQNLCLLAKLFLGSKTLYYDVEPFLFYILCEYDELGYHLVGYFSKEKRPSSQNNVSCILTLPIHQRKGYGNLLIDFSYLLTRVERKTGSPEKPLSDMGLVSYRSYWRLVLCRFFLERREPDLKLKSGLSIRQISDHTGLTSDDVVSALEGLRCLVRDPESQLYALRVDLNYCRSYVAQWEAKKYVKLKPSALVWTPYVMGRNIANALDSIPGLSRIDDNNGDEDEQSKNEEQPHEFISSQGGVACHQSPVSQTQFISQNDKELQMHISTTDIGEINTNTDYPTVGFIPQHSEAQGASSPKSWYTLYEGIPPTRFRVFPPMTGGRRLEKPKIPSASLFSQPTVPSSLIMDDHQSIMTPTIQKRAPGRPRKSTIQKRKGSGGTGRGPGRWPKGTKKSDYGNADSGPGLPPGWNNATQITDPLRSETELIVSDTPDGDKIVCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLK0</accession>
    <name>A0ABR3YLK0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Purine-cytosine permease fcyB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_005894</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000228">
        <property type="protein sequence ID" value="KAL1889171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026030">
        <property type="entry name" value="Pur-cyt_permease_Fcy2/21/22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806:SF5">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002744">
        <property type="entry name" value="Pur-cyt_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="135"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="201"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="270"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="328"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="365"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="393"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="436"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="471"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR002744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1889171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="496" mass="53762" checksum="D1142A87D9A3FAC8" modified="2025-10-08" version="1">MDSNASEKGQAPSLEVSIPSASTPRNNGGWKTVVSRALKSGRLEYNGHEPIPEYERTNTNFLDVGTLWFCMNANILPITFGMLGTSVYGLSLRDSSLIIIFFNLLTASVVAFLSTLGPKTGMRQMIQARYSFGRYLVCVPVVLNLATLTGFCIIMAVIGGQCLSAVSTGKLSPSVGIVIMALMAMVISVFGFHTLHIFERYAWIPTVIAIAIAAGAGSDKLSEQVVPESSATAPQVMSFAMIVSSYMLPWGCLSSDFSTYMSPKAPSWRIFTYSYIGLVLPTILLMTLGAAIGGAVSNVPEWEELYNETLVGGALAGMLLPLHGFGRFIVVILSFSLLGNLAATSYAITLNFQQLAAPFSRISRYIYAVLLTAIIIPISIPAAKHFLVSLENFIALIGYWSAAFLAVVIVEHFVFRKGDCSQYDPEIWNDGARLPLGAAAMSACVLSFALVIPSMAQVWWVGPIAEKTGDIGLEVAFFLTCLLYVPFRAVEKKYYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMC2</accession>
    <name>A0ABR3YMC2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000236">
        <property type="protein sequence ID" value="KAL1888982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027796">
        <property type="entry name" value="OTT_1508_deam-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14441">
        <property type="entry name" value="OTT_1508_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="540"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="602"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="895"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="968"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="550"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="613"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="629"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="667"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="689"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="766"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="795"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="980"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="999"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1034"/>
            <end position="1046"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1074" mass="114550" checksum="6623A275AA940C27" modified="2025-10-08" version="1">MSRSQQALAIAANIALARQVYDIPEDPITHDPIANFKNRLPPPELYHLPPQKEVELAHALAVTSKLKDESDYTSAVTVTEDPKRRRLLVLLAVNRASPEDGQEELDGAHAALERVLEIMSEVRSRNNDGMQDRILGAVVTACHAKILARMGLAPCRHNKTRMPLDGKLSQAVQAVNNLLWQKQPPGAQEFRHFGTIVLQLIAKWRQAPDDIDRLVAVVYGLHELHENVPTLDRLMRELPPRSIVPSAAKSIAAVVAKTAYYVRVARTLYRTAKKYPIARRARIIPINLPPIAFAQTPLPMHGTPGAAAVLSRDTKIKSLCSGAPPATLQTIVRYLNSSTKASRAGESFEEVMHTSLTGRIHAEMQIIYYCNMPENSHILSPRAVCASKASCFLCNSYVTAHCSVYVPFSHGRLYTNWRLPNMCGLEIPEAAFVGRLETTVTWGLGLLSAYGHAPQRPEPAQSVVMGLTSSTTTIGDLGPYDAEREDAEVWYTEDEMENYVDEITEHGDDDDELELETEPHLIREHDDDDDEQNNLMDEYEDEDEEVQDSGPYQNGVSVNGTNPYGSNPLGTNPMGTNPMGTNPFGTNPMGSAPHGTAFTAPVIVSSHRELANETADVETAPTTPEPEPELQQVEALAAAKREAVASSESDPLSLPERPKQHFIRAQSAPVSSSSASRPEPPAASVTEAVAEEQVVEAETDEAIDTDAGSDLVVSEISERPSAPDLRAQSAPEPSKNTHRPAVPTPPTHAATPFVFAEHERRESGTYAASYQSTAVSDGSVSDGDIETRDKPPQMLRSSASTRPVVVNSTAESVPSPIVEPVVQVVEVANTAKVAESVATSVAEPDPQPAAVAEPVTVPVTVVVAELATQSPEIPAKAAARELKEEPDAAEALVPTVVKDAQPVAQPDAEPKPEPKTTVEPPAAPVVVAAPAELAILGAVSVADFAIPAPVTAVAPAPAAVEVGVPPKAEVSETAEPTAEHATSASAQTTVPDQAPVSAPTPTAPISSQTVAPVAAVNQTPAPAQAGKDTTTNIASAPVSVASGPSSETRLKKGLRYRLKSLFKKGNKTAAAAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YND8</accession>
    <name>A0ABR3YND8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_005702</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000209">
        <property type="protein sequence ID" value="KAL1889622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1889622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="402" mass="45260" checksum="B83AD12B698AF48E" modified="2025-10-08" version="1">MISHYVPVISSNLTIILTTSPTPSTPSTDLLASILSSFHTHCPILLQCNIIVVLDTFERISPVLRLKKGQATPELAAAYETYKAKTKALFLHQWPGPNGLCPTGLYRNTPSPHISIDIAEYGSPGQAHTSVTLDITEYLAAGVTLIEPRERLGFGLSVRSALRRVTTPYVWVQQHDWALDAPIPVNAIVRVMHANHLCEHAPIRYVCLPSVRMVGYAASMLAVKHPMLRQLTEKLKGNYSQVAVGKEEEVIEDTEERRKAMVGERVSLTPMFFWHDKTHIASTEHYKQRVFPSRLAMPRGAFIEDTIGHRARDQMKAGDFTKWATWLYYPKDGQQLCLRHLDGRMWKGMEAEAVLQKGYMHAKAVTAQKRAEEAERNRKRDGRGDEEISAELLWVGSDIRMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP92</accession>
    <name>A0ABR3YP92_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA 4-demethylwyosine synthase (AdoMet-dependent)</fullName>
            <ecNumber evidence="4">4.1.3.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">YPO7</name>
        <name evidence="16" type="ORF">Cpir12675_005610</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>N(1)-methylguanosine(37) in tRNA(Phe) + pyruvate + S-adenosyl-L-methionine = 4-demethylwyosine(37) in tRNA(Phe) + 5'-deoxyadenosine + L-methionine + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:36347"/>
            <dbReference type="Rhea" id="RHEA-COMP:10164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10165"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64315"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="EC" id="4.1.3.44"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">tRNA modification; wybutosine-tRNA(Phe) biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TYW1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.44" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000201">
        <property type="protein sequence ID" value="KAL1889922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102521">
        <property type="term" value="F:tRNA-4-demethylwyosine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013917">
        <property type="entry name" value="tRNA_wybutosine-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034556">
        <property type="entry name" value="tRNA_wybutosine-synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13930">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13930:SF0">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE TYW1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08608">
        <property type="entry name" value="Wyosine_form"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00284">
        <property type="entry name" value="tRNA_wybutosine-synthesizing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01071">
        <property type="entry name" value="tRNA_wybutosine-synthesizing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="14">
        <location>
            <begin position="134"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="15">
        <location>
            <begin position="456"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="79"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="322"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="754"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="331"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="775"/>
            <end position="796"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1889922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="796" mass="88921" checksum="A97A664809FF9321" modified="2025-10-08" version="1">MDASPVELARENLMANADQATANDLLDLWHQYRNVALTVFAVMLMAIRLYFSSEEREVLVAIPKILEDKKNNNKAIDVKSKPRETQAEIPSESLPEAKPARDKKAGPKRIVGGLRKTTSPSGKTRLARGRKLQPLVFYSSVTTNTERIAGTFLPQLNDVLAALDLGEEASAQVSLLNAEMLDLAQIDFDDYFVAPPVAKEGVELVYLFLLPSYNIDTINDAFLQHLQETHYDFRIDTAALSGLAGYSVFGFGDREGWPDENEGFCFQAKELDRWMSKLTGGKRAYPVGMGDTKTDYEERLAEWLQGLQEVFVVIANTGGLGEGLPGSGGADESDVDDVSADEEEDSEVYVDPATKKTSAGDLGDVEDLGKLIKGSTDLAENTDFTNYGTSNKRKKTAAATAAQAVAKEMVPVNSPTYKSLTKQGYAIVGSHSGVKICRWTKSALRGRGSCYKFSFYGINSHQCMESTPSLSCSNKCVFCWRHGTNPVGTTWRWVVDPPELIFEGVKKNHYQKIKVLKGMAGVRAERYAEALRIRHCALSLVGEPIFYPHINEFLTMLHREHISSFLVCNAQHPDQLAALKAVTQLYVSIDASDRESLRRIDRPLHRDFWERFQRCLDILRAKRNKHRTVFRLTLVKGFNIDDEVDGYAELVSRALPCFIEIKGVTYCGTSTSANAGLRMQNVPFYWEVCDFVRALDAKLRDRGLDYGIAAEHAHSCCVLLGSGRFRVDGKWHTQIDYDKFFRLVEERGADGDWTPEEYMGAETPEWATWGNGGFDPRDQRVDRKGRPIEAKKEPSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ16</accession>
    <name>A0ABR3YQ16_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000184">
        <property type="protein sequence ID" value="KAL1890401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="289"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="326" mass="37249" checksum="5515AC03C0FFA3B4" modified="2025-10-08" version="1">MSSSPKAPRTERRAKKDPGHIKYARLTIPTLTAEDREIIYNLVNSGCVKGATKRTVTMEFETTDSIAAAMQSHGGLRNSSTQRPGRPHAINEEMATRLRIALILTPTATAEQLIAKTGCTCSARTVQRNMPDLRAEADRLAEYVIEEFQQDMFDLRGSARDIQIPESRQLAPAPLLQPAFVYGASTEYKGDKYQKERSTQRYKRSGQAMLEESGGQAFQSHHKDYDFRTPNNSNNTHQTSYQTPPYHYESEKHTPQLPSQHHRQQTPQHYETPQYDHSTRCQNQPQNNLQYRYQPQPLYPQYAGQSQEYGISNTWMSPEEYSSSQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ63</accession>
    <name>A0ABR3YQ63_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">diphosphoinositol-polyphosphate diphosphatase</fullName>
            <ecNumber evidence="1">3.6.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SIW14</name>
        <name evidence="9" type="ORF">Cpir12675_005566</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:79699"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:74946"/>
            <dbReference type="ChEBI" id="CHEBI:77983"/>
            <dbReference type="EC" id="3.6.1.52"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:79700"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + H2O = 1D-myo-inositol hexakisphosphate + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22384"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="ChEBI" id="CHEBI:58628"/>
            <dbReference type="EC" id="3.6.1.52"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:22385"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein-tyrosine phosphatase family. Atypical dual-specificity phosphatase Siw14-like subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.52" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000197">
        <property type="protein sequence ID" value="KAL1890023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004861">
        <property type="entry name" value="Siw14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126:SF48">
        <property type="entry name" value="INOSITOL PHOSPHATASE SIW14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03162">
        <property type="entry name" value="Y_phosphatase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="7">
        <location>
            <begin position="153"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="8">
        <location>
            <begin position="222"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="16"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1890023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="306" mass="32689" checksum="5EBCE61CCECB3633" modified="2025-10-08" version="1">MTQPTFVLSNRRSSEHSLAASASASASTTTANRKALPPPQRNSTNPNMVTNIATVASISTPRTTTTYQPAANVSRFMSTLPLPVSVSAATMVPVHNSPSPHQTAVALAGAYNDVNTAAFELHSSSSSSISDLSSSTTKIHGQPANGLCKAPANFGIVAPAVYRSDFPKEENLSFLGNLGLKTIITLVKKDSVDPDFAHFMAANGINHCVIDMEGTKKKAIPADVMNAIMEMVCDERNQPVLVHCNHGKHRTGCVIGVLRHLSGWSVSDILTEYNLYAGEKARDCDLAYLANFDISSFASFPGRRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ88</accession>
    <name>A0ABR3YQ88_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nascent polypeptide-associated complex subunit alpha-like UBA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000182">
        <property type="protein sequence ID" value="KAL1890476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14361">
        <property type="entry name" value="UBA_HYPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052617">
        <property type="entry name" value="Huntingtin-int_K"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038922">
        <property type="entry name" value="HYPK_UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044034">
        <property type="entry name" value="NAC-like_UBA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31184:SF2">
        <property type="entry name" value="HUNTINGTIN-INTERACTING PROTEIN K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31184">
        <property type="entry name" value="HUNTINGTIN-INTERACTING PROTEIN K FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19026">
        <property type="entry name" value="UBA_HYPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nascent polypeptide-associated complex subunit alpha-like UBA" evidence="2">
        <location>
            <begin position="74"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="116" mass="12073" checksum="0AB31315866C7BCC" modified="2025-10-08" version="1">MSEKPIKTVDADEESQDSAAKFAEDRKAASAMAALDINGTNDSNGANAVDQDAMNKAIKGLSKSGAAKTAAKAVKVDQADVLLLTEQLELNKLKATELLKQHDGNAVKAMVAFIGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQL7</accession>
    <name>A0ABR3YQL7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_005295</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000177">
        <property type="protein sequence ID" value="KAL1890663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008313">
        <property type="entry name" value="GH125"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31047:SF1">
        <property type="entry name" value="DUF1237 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31047">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 157 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06824">
        <property type="entry name" value="Glyco_hydro_125"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01149">
        <property type="entry name" value="DUF1237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1890663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="135" mass="14645" checksum="A2B56B5EBCE0BB95" modified="2025-10-08" version="1">MEAMTRNIREAISKHAVIDGPGHVGPMYAFEVHGFGGRNLMDDANIPSLLPAPFLGYLNAEDAVHQNTRKFVLSKQKPWYCDGHVINGVGGPHIKPGAAWPMSSTVQIMKSSNNTEIEKALLELLSSTNGIGLIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRJ7</accession>
    <name>A0ABR3YRJ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Sexual differentiation process protein isp4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_005260</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000174">
        <property type="protein sequence ID" value="KAL1890702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="199"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="230"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="255"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="297"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="369"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="439"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="498"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="525"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="609"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="646"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="676"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="708"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="753"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="72"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1890702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="818" mass="91004" checksum="AC22D6562087FD20" modified="2025-10-08" version="1">MAHSSVSKAASGSTARSLEPRASYSKSKALNHDSGSEAKATHDNDDDDGGFSENEGLLASSSDGIELRHLHHKSKPINSNSDSDATLPMSSDSDEDGDWEENSPYPEVRAAVHNYDEEMPCDTVRVWVIGLSLVIFGASMNSLFSLRSPSISVSALLAQVIAWPLGHGWALLVPNCTFNIFGRELSLNPGPFNIKEHTIIVIMASVSFSVAYATDIILAQRIFYNQNFGLVWQLLLTVSSQSVGYGIAGMLRRFLVYPASMIWPGNLAAITLMNAMYEKVPDRDPSVLGGNMLRYHWFGLMVGASFLYYFIPGFLAQFLSVFSIVTWFAPKNVAINQLFGGENGLSLLPLTFDWTQITGYVGSPLVPPWVAIFNTLIGVVGFYIILTALLHFSNTWYSHYLPISDSATYDNLGHKYDTSRILSPEMTLDENAYKNYSPLFISTTFAMAYGLSFAAIASLVVYTWLHHRHQIINQWRDSTHEKPDIHMKLMRKYPEAPTWWYMSLFGIMMCIGFITVLGYPTNLSWWAFLLAIFLAFLFALPVGIIQAVTNNQIGLNVLTEFVYGYIQPGRPLALMLFKTYGFITMSQALNFVSDLKLGHYMKIPPRTLFLTQVVATTVSCFVQVFTLSASLATIPNVCEADQADHFTCPGGRVFFSASVIWGLIGPARVFSPGQIYYGLFWFFIVGAITPVLLFYGAKRWPRSFMKNLIAPLIFGGAGAIPPATPLNYLSWGIVGYFFQYHLRKFHPRWWTRLNFLTASGLDLGLALATVFAFFAFTMHGIEGPDWWGNRLGKNTLDAQGGAVLIKLPEGQAFGPKSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRR0</accession>
    <name>A0ABR3YRR0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_005315</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000178">
        <property type="protein sequence ID" value="KAL1890591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044574">
        <property type="entry name" value="ARIP4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056026">
        <property type="entry name" value="DUF7607"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45797:SF1">
        <property type="entry name" value="HELICASE ARIP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45797">
        <property type="entry name" value="RAD54-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24580">
        <property type="entry name" value="DUF7607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="990"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="1348"/>
            <end position="1498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="128"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="358"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="679"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1821"/>
            <end position="1843"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1885"/>
            <end position="1904"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1917"/>
            <end position="1941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="143"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="688"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1828"/>
            <end position="1841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1887"/>
            <end position="1898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1924"/>
            <end position="1941"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1890591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1941" mass="216224" checksum="419D5A22343C1A74" modified="2025-10-08" version="1">MNHFQVPEDPFFWDSDVLVAELYNPRESWNLPGIDVPDRDIFLQSFQRLRISGRLFLTWGSIQHNTYTELFADLGIVLPEHRLWLLDALEFLQSRSNTYTSWNMSRTLRLKSGTSLSARSSVSQFPAMPFMPNAQQQPSVQRLQNQQSLSQNSSPGMRSSQLATLGHASNTFASPAQFVQTFTMSASPVSALPPSQMHVQAAQTLSQPHLQTPQQGPLEMGEPPMLNLPGPDPNVVINSLPAPDNESNIQLPNVIQNPPVRPPDHAPTFSKPRRRVHPTPIITTATEVPQTSKLGLCRPFLTDGTFSLQNRYPDSDDSSDSDGEGFSMVNTRRYARIQPKKAYKAVISVLNGRIQSGNLTSCDDPASDGESYFIGEHVGPDSSDLDHQGSENEDQAWHTAQNFLTTQAVNKIIDERISQFVDIFTSNYLPRLRAKAFELWNEGRLERQIGSRLREASATVAHLENRISSIRTQMHLTKWSSRNSLWHQTMCLELSVIELEKKKWLIELVKGPRPAKIPASVKPRVKRRKIEYTPSDSECEVISDSESSIGFIVDDEAEEETMLPGASRGPIPPAVAPHPLYPESDVEKLTPAVAPTENPILKEMNVDALQATPLDKSSENDIEMLYPESSNPIPTTAASIDLESLPAKNGEKVDEIEDVVMEPYSAEFGSSTISNVSAAIQSRSQEKSASPGAPTSTSTRNADESAFCSENPPPSPSVVSISDGGGDDEEAEDFVTYDLSLWKAIPNRFKCLLPKELLEIHGDMGRALVGAIYSMSANLRQKLFIEVTACNNLPENFWNTVMIRSSTETAVQIAAIALFKCAIGGTFDHIRPEVFQKKKGSITGALMQCHRNLPPFYRALYDIQAGFPQTADDMIAGSDESGVEDQAGVDLPNQASKKKQRFISKEVTAAYEERMRREQARWDEKVELAKKSKLQAEAIPDEKSRLIINMSKSEDEPFIYIPDSIANATSEIFDAQIEGIRFIWDNVVSNDGEVSSNGCMLAHTMGLGKTMQVISVLLAIVEATHSSNPAIVSQIPKQYRRHRFLILCPAPLVDNWIKEIERWAGSSMMPQVLALGNMSSGQRIAVVKQWCENSGCLILSFALLGRLFKTGDEIMQIIANSADIAIADEAHALNNTGTNIRRACDEIKTMAKIALTGSPMANNTLEYYHMVNWVAPKYMGSEEDFKISYARPIEDANVADATPNERYRARQLLKRLTKKMRHKVNRATLASLPINVLPRKQEYIIGFPPLEGLQQKLYSEYVNLHKQYGFSSDFGALDNLSIILTHPKCFAMKLRGTRAGRRGGDTDNEIVERETLPKEMSQALLEIVDQEPDLDNVNLSWRSRHIMSILDECRKVKEKVLVFSQYLDVLDYFEDIFICQRRKFCRIDGSTDKRVAMVDRFNQEDFEVFLIATKAGGTGLNIQGANRIIIVDFKYNPMWEQQAIGRAYRIKQTKDVYVYRFVGSGSSEAVMFHKAVFKMQLTDAVVDEKTQVARSELRKGSKVVHLTEPISQPYDKYLGVDDVLDKLLTDNPSQKGIVYVDHTDTFAEPDEEIPVSDDIAKHVNDELRAIEEREKNGGHAVPYAPLGHGSAAGGSQVYRRNAKGQFGAARDDTNSSSSIGDHTMALYQGLPYHQRPRLARLQSLVNEHNSMPAHNGQLPLTLNGSTDTDFPEHAIFRQNLRLGFMRAANLTSKAAKIPSQAEEDKATARSMIIDDYLSVNIRGDLPRRTRENLVLDLMGQDRFALAFLNQVHGLTNNMIAVSMDRVLREKHRELEVMDEHKYRDLFPVELRTHYWGQAVLPEDTVANVATLVTPATVVAETPTTPTASGNTSVTSNSTPQAKSVARDNIHASLLHKVGTRQKRQLLPTHRDPDHLAQMRSRIVANAAATQSPASSSNTDKGHINRDLAVLEAVRRRRDRQASLVSSVSSTGSVSTSGSRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRY7</accession>
    <name>A0ABR3YRY7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dihydrofolate reductase</fullName>
            <ecNumber evidence="2">1.5.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_005257</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 5,6,7,8-tetrahydrofolate from 7,8-dihydrofolate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the dihydrofolate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.3" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000174">
        <property type="protein sequence ID" value="KAL1890699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00209">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="entry name" value="Dihydrofolate Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012259">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017925">
        <property type="entry name" value="DHFR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001796">
        <property type="entry name" value="DHFR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069">
        <property type="entry name" value="DIHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069:SF3">
        <property type="entry name" value="DIHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00186">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00070">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="Dihydrofolate reductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00075">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51330">
        <property type="entry name" value="DHFR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHFR" evidence="8">
        <location>
            <begin position="5"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1890699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="209" mass="22924" checksum="8FED4E34D0DB2BC6" modified="2025-10-08" version="1">MTTPELNLIVAATRSMGIGNKGGLPWTGLRKEMAYFARVTKYVPAGTAPGAFNAVIMGRKTWESIPTRFQPLKDRLNVVISRSYSAPQPNSSDSANHVRNPVQAPSLESALAYLSALPASQLARVFVIGGGQIYAAALQIPSATRVLLTQIRSEFECDTRFPLVFGEGGDSGWVRASDYDWEMWTGGESARGVQEENGIDYEYQMWEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRZ2</accession>
    <name>A0ABR3YRZ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005294</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000177">
        <property type="protein sequence ID" value="KAL1890662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="326" mass="36197" checksum="BB07A13A194DAFBD" modified="2025-10-08" version="1">MSGKNKLAKMREKEAEYMHNHAEKQAQGSSALETPPPYTDLALDSTSSLIFSETSSFGVQSSSLPPASALVPPPSPYTNHIFPSTFGVYECILSRTRTIGPHRNEPVLCIREHMRVKSGFDLVLHNGPDTSFEPLAGLTQKFFKRGFGISMPSPAAVLERTQTGTKTFVPNSLDITEQVEPAAPSIRGRRLEFTIEVGRVRETFQWRERKGPSYSLRCRRHYVLLRRAADRPPDGAPPGSWPPAMQDDPGSERDNTSSMLRESEYEDMEVVAQWDTEAIRGTKLTTFKFVGTGSTGLLGPRWEVIAVLSGLHVCIMEADQSRARTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT69</accession>
    <name>A0ABR3YT69_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cullin family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_005061</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the cullin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000160">
        <property type="protein sequence ID" value="KAL1891215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1310.10">
        <property type="entry name" value="Cullin Repeats"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.130">
        <property type="entry name" value="Cullin, Chain C, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045093">
        <property type="entry name" value="Cullin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059120">
        <property type="entry name" value="Cullin-like_AB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016158">
        <property type="entry name" value="Cullin_homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036317">
        <property type="entry name" value="Cullin_homology_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001373">
        <property type="entry name" value="Cullin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019559">
        <property type="entry name" value="Cullin_neddylation_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11932">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00888">
        <property type="entry name" value="Cullin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26557">
        <property type="entry name" value="Cullin_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10557">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00182">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00884">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75632">
        <property type="entry name" value="Cullin homology domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50069">
        <property type="entry name" value="CULLIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cullin family profile" evidence="5">
        <location>
            <begin position="456"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="373"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="844" mass="96275" checksum="37349302471DF4E6" modified="2025-10-08" version="1">MMSGRLAGGRSGGQTRIRPPGSIRVSLSGPRRLATETTPDHLWSVLRSAILCIHRHQSSQLVFEQLYRAAYNLAIKGQGEFLYEHIRSLETDWLQQEIFPPLSKQLKLVESSYLLGDMHSENERYQVGKAFMALLKDLWSSYGTAMNMIADICMYLDRSYIEQNNKPSIYDATMALFRDQILLSTGEGNRPALEVLVRIIIDQVSMERSGQVVDRLLLKSCAYMLNSHVQDEHKKDSKDLYTSNLVPELVRNAQEFYQEQCQLLVDEGTTPSWITQCNKLIDNEIERYNTYLYESTLPAVIDVLHESLIRKPLAHFIDLGSSGLHAMIDNDRFDEIRQLYELESRIDSKACQFNRALQEKIVDMGKAIEKTLNETDFSTPPPPKPGADDGVAASETKQQSLTAAAQQTAAAMMWVSQVLELESQFSKIVMRCCDGKAHIDNAVNKGFMNLVNRFQRSAEFVSLYIDESFRKGIRDKEEPEIEALLEQMIKIIRYIDQKDLFERYYQKHLARRLLYKKSESSDIEQLMISRMKREFGNNYTSKFENMFHDLDLSQGLTAKHRESIALSESPSNVEISVTILTHGAWPADILGQTKRVGKEEKLITCNWPASIKPTIEKLNQFYLSQHSGRTLSWVGALGEADIICTFPAIPGKSGQLGRERRYELHVPVYGMIVLDLFNDIPHGQTRTFDEIFEQTSIPHSDLVRTLLSLSAAPKCRMLLKDPATKNVKAGDKFSFNTAFVSKTMRIKAPVVTATAKVETDLERKATELKNDMSRAYFIDATIVRIMKQRKELAHAPLVSEIIKQMTSRFTPDVAQVKKRIEDLLARDYLERIEDVEPATYRYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT85</accession>
    <name>A0ABR3YT85_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_004902</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000150">
        <property type="protein sequence ID" value="KAL1891593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF36">
        <property type="entry name" value="PROLINE-SPECIFIC PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="69"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="327"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="372"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="401"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="445"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="474"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="6">
        <location>
            <begin position="41"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1891593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="543" mass="60053" checksum="B61EACAFF7F5CD51" modified="2025-10-08" version="1">MAESKERAATPSSEAGEAIVFDPEGDMSVETQLQRGLKSRHIQFLALGGAIGTGLFIGSGSILHSSGPAALFLSYICMMALVFFIMNSIAEMVVYLPMKGITMPYFTKRFVDDSLAFAAGWNYWYAYSMLTAAEATAAGIIIDYWKPPVNIGVWIAIVLVVILMLNIIAVSVFGEAEFWFASIKLITIIGLVILGVVIFFGGGPNQKSMRGFSYWKSPGAFTEYEASGSAGRFLAFWRAFIGAGFSFVTSPELIGIAAGECVAPRRNIPKAARRFIFRLAIFYGAASLVIGIMVPYNDSRLLGGNDASASPFVIGIQNVGIEGFDHVINAAVLTSAWSAGNSFLYSGSRVLYSMSKTGHAPAFFRTTTAKGVPYVAILATWFPSILAFLNVSNRGSRVFSWFTNISTISGFVAWIVVLITYLRFRKAMEYNNMLDVLPYRTRFQPYGTYFVIVVISLLTLTNGFQILIPRNWSFQDFLAAYITLPIFLALYLGHRISTRSKRWAIPIEEVDCITGKKEMDELAEMDRPPVPKNWMEKAWYWLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTD6</accession>
    <name>A0ABR3YTD6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005128</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000163">
        <property type="protein sequence ID" value="KAL1891120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="693" mass="77906" checksum="09D78ACA06C6088D" modified="2025-10-08" version="1" fragment="single">KNISTLNYLVLATMTCDSIKPTAAPHRSRFAPIPIETTYESVRLPRLQALAVAPPASVLASVPTPDLTPESSPRETTSAPKFPLFPTSNSSVEISTQHVEDTRPSRVCKDSLAIPQPGHAPCRHLDCVGCAKQRRRFAPQLVETSRRARRIGDSGPATRPTDKTDITPYTNHIYLSHTRSKKRRNNDHKEHRVYTSDRARRETDDAAFSSYLLQLAAQEVERQIQEAALAAFPNAQAREGGVAHFYFRDSEEEDSPSAGASPRSTQDEVGIGGVVGPHFHVRTHRAHHASTINLHRQRKSSDLDWWHKNMQEHAQKKGQAQAQVQAQTDTPMSDCAIDDDEYDEFEGMDIEMPPPDPLWLTTNRSASCMSTESDVYIDGDDYSMSYAPIDYSSSSKSHSKPSPPPVIASISINRGDPGGNGFGGRQFGGFARFGLPKESDDWRRARLGLSPPMLGKEIKFRMCPSPKASVTPQPAETPQQPISLGLDRSCYYEEVSTPPGLWRGSCLRTRSNEKTTYVPTGAPIHEMYLATPTEPLSPSYDPFSAAFGACNSPWPKKDQMFTHNRVRREAADARAKEKDRIEVRIKDEFDDLFVTQVFNYLSLGYPPTAQAFDQELSKISRVPVEELSKDDEYRMKSLKTFDSEEHTIPEDERCVRWKALKMYIFEWGRQHPDLDNCRPVAWDMRERRGSWAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTH4</accession>
    <name>A0ABR3YTH4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">3'-5'-exoribonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RRP45</name>
        <name evidence="9" type="ORF">Cpir12675_005084</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000161">
        <property type="protein sequence ID" value="KAL1891148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11368">
        <property type="entry name" value="RNase_PH_RRP45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050590">
        <property type="entry name" value="Exosome_comp_Rrp42_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033100">
        <property type="entry name" value="Rrp45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097:SF14">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="7">
        <location>
            <begin position="32"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="8">
        <location>
            <begin position="191"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="296" mass="32728" checksum="0FF8F129A799F6C8" modified="2025-10-08" version="1">MPREAEPSQIEKDFVLQALDEGLRLDGRTLSQFRELNISFGDEYGVAEVTLGKTRVLAKVAAEVTVPYPDRPFDGVFTISTEFSPMVSPAYEVNRPNESEMLLSRILEKTVRRSGALDTESLCLIAGQKCWAIRVDVHVLSNDGNLIDSACLAMVAALRHFRRPDTTIDGGVVTVYTPAEREPVALSWLHSPLCVTFGFYGDDGKIVLLDATHLEEQLRQSAFCVSLNKHGEVCHMIKMGGIAVEATDMLQCGALAMEKVRELTNLLEQKLQDDAKARDKGGFMAELRAENERAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTP1</accession>
    <name>A0ABR3YTP1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_004882</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000149">
        <property type="protein sequence ID" value="KAL1891661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05474">
        <property type="entry name" value="SAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033876">
        <property type="entry name" value="SAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF65">
        <property type="entry name" value="ASPARTIC-TYPE ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047210751" description="Peptidase A1 domain-containing protein" evidence="7">
        <location>
            <begin position="20"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="8">
        <location>
            <begin position="429"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="785"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="785"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="840"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="870"/>
            <end position="885"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="999" mass="105154" checksum="02F7C0D159A032CA" modified="2025-10-08" version="1">MARYSLLFLSLAAAPLASAWPQLFDSPAAIDIVARGGAAAPKIPYEVIKTREATPVVPGVAENAQPIKPDDEKHNLVRSAKFRGSALPTVADDPFTVTLPVDLGDDSLDTRDIGSVPEFKITLVRSDNKIPRGLPVVNGDPNALYKITIPITAEQKRGLPVIDSDPDALFKIALPTKMGTSKRSALNHGVIELPAKFQVIEDRALPVVEDPADFFEVTLPVSIDARGLPVVSGDPDSLFKITLPLVKSPSSSKRENSVLSSSPDLHLRVPIADNNKVKRALPTGTTNGDSALSITLPVAISKRQHVATGKHSVTLRPPTEGENVPVKQYSNNKRQHVATDKHTVTLRPPTESENVPVKPYNAMQRRAEHNRKVRRTSSGVLKMPVIRGEKPSLTRRGSSEVDQALKKLQKRDDKNAISVALANRSDVAYYAQLDFGTPPQPIYVQIDTGSFELWVNPSCNTLMAGDKVFCEAVGVYDPNTSSTSGGLEEKKNLRYGIGAANVTYFSDSIGMGDSATMAGVQFGVANSTEDQFSGILGMGYGAGKTTTYKNFVDELADQNITHSRTFSLGLGAKDNEEGVLVFGGVDTAKFSGPLTKLPIIPASEAPDGVPRYWIQMENITLTTPEGKVTSAYEGSDIPAFLDSGATLTLLPPKVADAIAVDFGVTDGVSSNGFYAVDCEMAKAKGSVDFAFNGVTIHVPYHEMVRTLATSPPSCWLGLIPSTDFTLLGDTFLRSVYAVFDAENHNAYLAPYENCGEQLVSLGDGVTPDDITGSCTLEAVITTSSALSQAAPTSSQTAAVTETSSDAKATTTSDAEHAQTTKPTAEPADVQETDGLGGGTMTSDAEQKMTTDTPEPTESALSKKPIVASNTTPLEPSATSTSTTTTIATTDYMPAAEISSPPLATDAPNLAVAPSATGAPVAEVPAATGDGVPGNSGPVNDTSGELATTSPVPGAAFPTSRTSSAGAVQTAGAQRMLVELQWNAVGTAALIGVMNAFGLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTP7</accession>
    <name>A0ABR3YTP7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Endoplasmic reticulum chaperone BiP</fullName>
            <ecNumber evidence="3">3.6.4.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Immunoglobulin heavy chain-binding protein homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">KAR2</name>
        <name evidence="13" type="ORF">Cpir12675_004833</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.10"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.10" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000147">
        <property type="protein sequence ID" value="KAL1891760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10241">
        <property type="entry name" value="ASKHA_NBD_HSP70_BiP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042050">
        <property type="entry name" value="BIP_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0346">Stress response</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046185399" description="Endoplasmic reticulum chaperone BiP" evidence="12">
        <location>
            <begin position="34"/>
            <end position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1891760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="666" mass="72899" checksum="A2B88A9859B69E29" modified="2025-10-08" version="1">MARSRSTLAIMFGLLAWTCLLFSPLAFVKSVQADEAENFGTVIGIDLGTTYSCVGVMQKGKVEILVNDQGHRITPSYVAFNDEERLVGDAAKNQAAANPLNTIFDIKRLIGRKYNDKDLQFDMKHFPFKIVNKDSKPYVEVEYKGSTKTFSPEEVSAMILGKMKDVAESYLGQTVTHAVVTVPAYFNDAQRQATKDAGTIAGLNILRVVNEPTAAAIAYGLDKTNDSTERQIIVYDLGGGTFDVSLLSIESGVFEVRATAGDTHLGGEDFDQRIINHFAKSFNDKHSVDVTKDPKAMGKLKREAEKAKRTLSSQKSARIDIESLYNGIDFSLSLSRAKFESLNEDLFKKTLKPVTRVLEDAKANREDIDDIVLVGGSTRIPRVVDLIEEYFGGKKASKGINPDEAVAFGAAVQAGVLSNEAGTEDIVLMDVNPLTLGIETTGGVMTKLIGRNTAIPTRKSQIFSTAADNQPVVLIQIFEGERPMTKDNNLLGKFELTGIPPAPRGVPQIEVSFDLDANGILKVSAHDKGTGKSESITITNDKGRLTQEEIDRMVEEAEKYAEEDKALKEKIDARNALENYAFNLKTQVADQEGLGGKLDDDDKETLTDAIKEAMEWMEENAATAETEDFEEQREKLSNVAYPITSKMYGNAGGADADDEVPSHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU21</accession>
    <name>A0ABR3YU21_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit F</fullName>
            <shortName evidence="4">eIF3f</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_005220</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit F family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000170">
        <property type="protein sequence ID" value="KAL1890824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08064">
        <property type="entry name" value="MPN_eIF3f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03005">
        <property type="entry name" value="eIF3f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027531">
        <property type="entry name" value="eIF3f"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024969">
        <property type="entry name" value="EIF3F/CSN6-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540:SF6">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13012">
        <property type="entry name" value="MitMem_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MPN" evidence="6">
        <location>
            <begin position="31"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="307"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="349"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="365"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1890824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="383" mass="42201" checksum="77A7B7A7141B7607" modified="2025-10-08" version="1">MATETANFLHLARPVVPTQAGLNISSSPVTVNIQSQAVLSILDHALRRDIDNNQTTRGIGALVGSRSEDGSEVEVRSTFAIPHKENADQVEMDLEYQKHMLALTLKASPRESLLGWYTTSHELNSFSALIQNFFSSPETGTAPHPAVHLTMSTDSAADIETRCYISAPVAVNAERAAESCMFIRVPHKVLTSEAEQSALEAISGAKDSDTRTAPLVSDIEGLSRSLETTLDHLGRVSEWVSGVLDEEEEPNTSIGQFLMNSLSLTPKVSAEQIDRDFNNHIQDVLMVSYLANTIRTQIELAQRLGVWSSSATEKDGEGKADGENAKSGDKRHNNNNNNNNNNKRHNNQRHNNSNNNNSNTNNNRGNREQREPREPREPRESAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU50</accession>
    <name>A0ABR3YU50_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004769</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000143">
        <property type="protein sequence ID" value="KAL1891910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37844">
        <property type="entry name" value="SER/THR PROTEIN PHOSPHATASE SUPERFAMILY (AFU_ORTHOLOGUE AFUA_1G14840)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37844:SF2">
        <property type="entry name" value="SER_THR PROTEIN PHOSPHATASE SUPERFAMILY (AFU_ORTHOLOGUE AFUA_1G14840)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="37"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="315" mass="35183" checksum="F476E8ADD45BBA3F" modified="2025-10-08" version="1">MISALYSTARNVVYGLDSDRQDITKMDPSRYAFQYMSDLHLELCSQYTTFEFQPTAPYLILAGDIGYLNDPRLEEFLAAQTRCFEKVFFVPGNHEFYGATYAEGMRLARAMASRLGSNFVLLQQDRTILTLPNSLLSSSSVGSSPKRRIHVLGCSLWSHIPLESSEAVRARIPDFNKIEDWSVEAHNHLHRSDLAWLRGELTALVPTLKPQDRVLVITHHAPIAAGSSAPDKTGSPVSCAFSSDLLKSGLDAKGVTAWIYGHTHYSNSITQGNTTLLANQRGHVFPENDDGFEKGCKRPAPDPEHRFDPERTIWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUB3</accession>
    <name>A0ABR3YUB3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000143">
        <property type="protein sequence ID" value="KAL1891916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="149" mass="16561" checksum="D5FCD019E46BB1F3" modified="2025-10-08" version="1">MSVQAMSAGPPPHIKLHHESNIPRAVTFNNPFQAEHAYLQQPRTFEDPNSIQLVSSAPDIPSGRISDVEYPFWVKNCTKAVPYDSKAYAGAHRSYSLANIRPESCHRRNSSITILPPPVVPSRTSTSSDTRSKKSDLERIRDASPPPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUY0</accession>
    <name>A0ABR3YUY0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Spliceosome-associated protein 49</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">sap49</name>
        <name evidence="8" type="ORF">Cpir12675_004798</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000145">
        <property type="protein sequence ID" value="KAL1891794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12334">
        <property type="entry name" value="RRM1_SF3B4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034158">
        <property type="entry name" value="SF3B4_RRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052084">
        <property type="entry name" value="SF3B4_spliceosome_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48030">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48030:SF3">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="13"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="101"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="312"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="374"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="312"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="337"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="390"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1891794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="399" mass="41996" checksum="02DB1546C9214BA5" modified="2025-10-08" version="1">MAQNRHWEQDKDATVYVGNIDERATPAMVYEIMLQMGPIHNLHMPRDRVTQNHQGFGFVEFRTPADADYAANVMNGIKLYGKSVRVNKASADKSRAVEVGAELYIGNLDMMVDEKLLYDTFSRFGPLINLPKIARDESGTSKGYGFVSYSDFDSSDVAIETMNSQYILSKQAVVQYAFKKDGKNERHGDEAERQLAAQAKKHNIVPESQLPAALRERGPGTGANATPAVAIPRGVPPGFDPKAIPGMVAPGMPPAVAMGLGIPPHGTMSPQYAPPVNQRGYGSRGAHSQNAAHSHVHQPMGLGMPVLPPAPTGLPARPPAGQPSFTNPADFHPGYRGAPPGTAPAGAPTGTASPVPAAGAVGVAPAGVAVTAPPGFGPPPGIAGAQSFPHHPPPGFSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV82</accession>
    <name>A0ABR3YV82_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent DNA helicase CHL1</fullName>
            <ecNumber evidence="17">5.6.2.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">ATP-dependent DNA helicase chl1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">Chromosome loss protein 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18 19">DNA 5'-3' helicase CHL1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="24" type="primary">CHL1</name>
        <name evidence="24" type="ORF">Cpir12675_004586</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24 25">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="20">ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M. May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres. Has a specific role in chromosome segregation during meiosis II.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="17"/>
    <dbReference type="EMBL" id="JAWDJO010000133">
        <property type="protein sequence ID" value="KAL1892300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18788">
        <property type="entry name" value="SF2_C_XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="RAD3-like_helicase_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013020">
        <property type="entry name" value="Rad3/Chl1-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00604">
        <property type="entry name" value="rad3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472:SF41">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE DDX11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9 24" id="KW-0347">Helicase</keyword>
    <keyword evidence="8 24" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="23">
        <location>
            <begin position="13"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="120"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00029709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00044998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00045008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00045702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00048954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAL1892300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="879" mass="98415" checksum="D238E62E38786FEF" modified="2025-10-08" version="1">MSSIESLSLQSGKSAKYHHPYTPYDVQLEFMKAVYGVLEKGDGQIGIIESPTGTGKSLSLICSAMTWLRNHKSSEFEQSVNDTKTQYLDEPDWIVDQLLSQKRRELGQKWEEREDKLEKIRQKEKAMEQRSNKRRRMEEAHAERAETDDIENRFLLEDMEDMGRNDNDMLSGFSKETRNLLSSLGLGGPRKKEDEDDVLEEPLKIYYASRTHSQLSQFIAELRRPEFPSSLPISLQSSDGTDKSKEPVKSIPLSSRKNLCINSQVSCLSSVQAINDRCAELQQSKSGAKCKYMPGEDLLSQTHQFRDTALATLPDIEDLYRLGKSLSVCPYYASRTAVAGAEIITLPYPLLLQKSTRDTLGIKLEGNVVIIDEAHNIMDAISSVHAASIKLSELNRGRQMLGIYVKKFGKKLKPENRVQVGRVGRVMECLISWLTEAQSGKGEHAIVSATELLSRKGADQVNMFKLVEYVQESKLAYKIEGYLSYVEAEQAKQEGKSAPPAPSKPVLQTLVSFLLALTNLSFEGRIFFQKLEPRAQNGDVQLSYLLLSPTQSFASIASSARAVILAGGTMSPFNDYVSHLFPYLPPRKITTLSCGHVIPSSNICVWTLGNSRNGSFEFSFQRRSDKDMISQLGMSLLNMCNVIPDGMVVFFPSYGYLEEVVKVWQGNSKDHNNIWGRLQSRKAIFCESKTASSDETLQAYTAAIMKTSGVNSNKGAMLLGVVGGKMSEGINFSDQLGRCVVIVGLPFPNINSPDWKAKMEYIETSAVERLTKPEKQGEPLMRTSALLSHEQAVAMGKKEAREFYENACMRAVNQSIGRAIRHRNDYAAIILVDRRYGTQRIQDKLPRWIRGGMVSESHEKGLPELMGTLGNFFRAKKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV92</accession>
    <name>A0ABR3YV92_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_004726</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000140">
        <property type="protein sequence ID" value="KAL1892037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF46">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="22"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="300"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="312"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1892037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="973" mass="106906" checksum="6AED21DCC1A24AF7" modified="2025-10-08" version="1">MPSKPAPFPSKARSHFSRSRDGCLTCRSRRKKCDEAKPICGGCELGKRTCTWPPSNKSTQFYDGLEQAPSSATQSVRLGFVDSTSGMPSSDGIAMPHPPPPCKAPVQVFARQGSTSTGVRGHISAPEHNTSSSFTEPVLIHDPTLRKLQDNQAFSHVPKTPPPAPGIIPVQVSRRPTGVVPPHAPRFPKDSSSLTDFNPHPQSQTAAGLMIQAPAPSVDVVQPDATLYGTPNLDPHNSAEIYDPAMHHSVTPMGPEPYVPAPHEASLRASVISQGEPLISHVPTHIMATAPSTQAEMGLPQLSYFPEPPGSLPASAPASSDSPPSATKTYSASSSPVEFYSLPTNNEQNTDSMAGYGVAPMKGAQIPRGLGSVDQYEAYTIPEEQPGMPGMDYENTRRMNPLSISQLIGEASSTKATQPLLEGQEFILGNEEDNFELHQGPGESSGLQNTPPGARPPTPIMIAGYVNISEDGIVSPISNYDDINAGSVDAPEAIIAKLISEKLRPIEVLYDDAAGYEQNAVNTDTSGLRIRKQHLKNKKAKSKEMALQNIFADRRKRTLTHTERINRAIEVGSLHRTLYFTDGTDFDPRSHLLFKHYLDTVADQLVTCDESINPFRRHVLPLATKDDILLHAILAAGGAYFCFEDSVNPVLGDVSRQHYSVVLSRLGPALRSGRYTSKTDRVFLVTIMMLLNLFETLAGRTQGSILMHLTACRTILLSLIEDPPKDTHSEIGVIFGFVCECYCYSGTMAALSTLLCYGAPKIPIDYFMRDLSFLRKYPTYRGFLGIGHSLWEIIPEIVDLGQDRFQEEANGIASIEVFARYRNLLRRVETWTDPDDDGNMRMDWRNASSVYQHTLIIVLHNLYYNDLYSQEEVIADVRLRVEMAFPLLLSVALSSNVGMMMLFPCMVLASCTEQEWLKGTFRYGIMAAKFKSCSMKQALLVLERLWTDNSSEAFGPRGLGYIMKKHGVVFTMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVK3</accession>
    <name>A0ABR3YVK3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Meiotically up-regulated gene 154 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_004753</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000142">
        <property type="protein sequence ID" value="KAL1891922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018819">
        <property type="entry name" value="Nur1/Mug154"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28293">
        <property type="entry name" value="NUCLEAR RIM PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28293:SF1">
        <property type="entry name" value="NUCLEAR RIM PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10332">
        <property type="entry name" value="DUF2418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="401"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="478" mass="52737" checksum="F9D2AD1765AAFC70" modified="2025-10-08" version="1">MAPPPRRIVRKKPLSERLSAILNPMDFLLWLSEEMETREYDPETLGLKLGLAMHVVFLLGRSNSASEHVDDLFGDGGSSSSMAYLSRALVWTLVLGCLVNAYYTTTRVRLYRLFQHNIDAAPDTKSAKRVNVQSTPSAASPIRLFRHALRPESAEDRSHPDKTRDVWELAVWDPLPLCLRIACIFSPAHALVYLTFLPISRDDPQPSITVLNCLVLQTVLSLQLLLVQSCFAQQAKDTALVNREVMNEYNTKFVHPRLHPTVRDAATQANITETGNNTLRIEMSSAVGTPTTLLHRGFQIHPNTNYSKAYNPEGYNNTSFGHSNSPQAYTPTPASRPIQSIESPTLATALRGSLRKSMPAMMVSHGTSTGANVLKSRTSVGTMSGSASESYNFGGNMGVHTHTNSPLKKATSMGDMSHSPQNSREMAALEQQQQQQRGRLYAGTNPFAESRGKPYSSKPAHSASQLGRDAVSRSQRQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWP1</accession>
    <name>A0ABR3YWP1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphatidylinositol-specific phospholipase C X domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_004404</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000123">
        <property type="protein sequence ID" value="KAL1892793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051057">
        <property type="entry name" value="PI-PLC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593:SF113">
        <property type="entry name" value="SI:DKEY-266F7.9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045634626" description="Phosphatidylinositol-specific phospholipase C X domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidylinositol-specific phospholipase C X" evidence="3">
        <location>
            <begin position="45"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="334"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="354" mass="39540" checksum="F6D988221D1BF6B2" modified="2025-10-08" version="1">MYSSLFTILAFIAFSQAAKLRGVDDYWSFDVGAGQNADWMSNLADDTPLSSLSIPGTHRSLTDDLKSFTVKAQNENLDQQLNGGIRYIDISCQFHKFGIQVFSKRHKTSYTLASLLGTLNKFLAEHSRETIILRIKGVSLSNARSFQSFFKEFMDTDYYQSTIRRIYSPDTETITMAPTLGEIRGKIFILQDFKTSPPGRYGLPWNKYTVSSYMTKGTFGTERINSIWAKVKSHLSEAPSTKSTPSIQSNMLRVTYTTASSGVYPINLAAMNSPRSGMNKRLGEYLRDNKVDCYGIIVMDFPGQYLVQQILKFNDKFLPLDIPGVPHDSDDANVADQVDSSSTVSDDEASSADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX62</accession>
    <name>A0ABR3YX62_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Ceramide very long chain fatty acid hydroxylase</fullName>
            <ecNumber evidence="18">1.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">SCS7</name>
        <name evidence="21" type="ORF">Cpir12675_004311</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="18">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="18">Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 18">Belongs to the sterol desaturase family. SCS7 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="18"/>
    <dbReference type="EMBL" id="JAWDJO010000119">
        <property type="protein sequence ID" value="KAL1892943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014430">
        <property type="entry name" value="Scs7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12863:SF1">
        <property type="entry name" value="FATTY ACID 2-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12863">
        <property type="entry name" value="FATTY ACID HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005149">
        <property type="entry name" value="IPC-B_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 18" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="17 18" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="10 18" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="14 18" id="KW-0408">Iron</keyword>
    <keyword evidence="5 18" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="15 18" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="16 18 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13 18 21" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="20">
        <location>
            <begin position="5"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRNR" id="PIRNR005149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAL1892943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="370" mass="42734" checksum="09A300DFF9B4BA75" modified="2025-10-08" version="1">MPAARPTFTRAEIESHNSSKSCFMTINNKVYDVTDFVDDHPGGAELVLEYAGKDVAAILQDSDSHTHSEAAYEILDECFVGYVADKDISEKTNGPQGPDMIYENDRWVHSRTGMATEDDLSKDTDISDDYKKHKFLDLSKPLLMQVWFGGFSKRFYLEQVHRPRHYKGGVSAPLFGNFLEPLSLTPWYVVPIVWLPAVAYGLNTALQGESSLTIFKHWLFGFSLWSLIEYVLHRFLFHLDEWLPDNRVALTLHFLLHGVHHYLPMDKYRLVMPPALFVILATPFYRLSVAIFTYSWHSAVAVFCGGVFGYVCYDLTHYFLHHQNLPLWYKALKKYHLEHHFLDYENGFGVTTRFWDRVFGTELVEAGKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYC8</accession>
    <name>A0ABR3YYC8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CDC16 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cdc16</name>
        <name evidence="3" type="ORF">Cpir12675_004178</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000112">
        <property type="protein sequence ID" value="KAL1893395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF263">
        <property type="entry name" value="MITOTIC CHECK POINT PROTEIN BUB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="235"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="548" mass="60077" checksum="A19F59AA256AF1EC" modified="2025-10-08" version="1">MPSPTRNTHSPFVPPHSSSGPLVADITAPAPPRTQRTLRKLQSAHSLGAKASTQIYPATPVEGLHIHHQVSQSSLKQRSSQLPQPSPSAFSSSFHHQTATPPRYQLHHQASQNLHSSRTTSQIPTNTQPQKQKQLPQLQSSPLARNGSPQKKDAASLSGMSPLSRRTRANSDANGTVHPLDSSPLTRKPKRPQYANLGMSVQAIVRDGPPDGDYLGTLETARYKILEEGIKSDSDGMSSVRIYAWLILLNTPIMATDDYLALIHRGASPAYAKIRNDTFRTLTTDPLFRRRVSEASLIRLLNAIAWRLHDGREKTRRERSSLAGGSTIGNFIGAGDITESSPGTDSSVHSSPAAKNRARALTLTTEGSEQNVMPEPGTYVQGMNVLAAPFLYAARSEAEAFTAFYALLTRECPGYIRGAMEGVHRGLALVDKVLAIVDKQLSSYLLSRSLRAEIYAFPSVLTLSACTPPLPEVLKLWDFLFAYGPHLNILCIVAQLYIMRDQILASPTPSNLLRSFPALQAEQIKKLTISFVQRIPRDMYAEIVDHAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYG1</accession>
    <name>A0ABR3YYG1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Chromatin assembly factor 1 subunit rlf2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_004306</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000118">
        <property type="protein sequence ID" value="KAL1893072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048800">
        <property type="entry name" value="Cac1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022043">
        <property type="entry name" value="CAF1A_DD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15272:SF0">
        <property type="entry name" value="CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15272">
        <property type="entry name" value="CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A CAF-1 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21796">
        <property type="entry name" value="Cac1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12253">
        <property type="entry name" value="CAF1A_dimeriz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromatin assembly factor 1 subunit A dimerization" evidence="6">
        <location>
            <begin position="322"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Chromatin assembly factor 1 subunit Cac1-like C-terminal" evidence="7">
        <location>
            <begin position="534"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="469"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="87"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="195"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF21796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="593" mass="66227" checksum="7059BE12CC55714B" modified="2025-10-08" version="1">MSLLELQGSEDMMAVDVSRKRSHDEYSSDDELSSVASEDVAMFDAPNNDSPSQTKLPSLKPDSNPPSDNPKHATDSTTHQHKRKRLTATEKAAKLEEESLKKKEKEEIRLAKLAEKSKADAEKAAAKAKIDAERQVSKAKAEAEKAAKQAERDEKKRKKEEEDRRIQEEKEKKERSQLRLNSFFKRPLPTKTNEKSATGTPAKNAETTILTSETVNEYRKTFKPFFIKESVRVAPLAVETLDPETRAAKAKILDEYISQKCGTDIQVLPFQPIQSLNLPFKIPRRGVVYPPVKQLVETIHEQAFDDKSVQVSRTQLRRIPIKTLFFSTDVRPPYCGTLTGPQYAYGREFMARAARRPKYRVFPSVAYDYDSEAEWVDDEMGEDVDLDDDEEEIDDDDDMDGFLDDSEDAGIARGSLSKSMDPESTDICFETGQRQTTVPELYTYRMEFVLDSLSPTGSINPFSAEYWEPEAKRTKPAQTGGTTNSKMPPPPTTNSPANAFEALVTPSSNIASATSEAPIASTPQALELKRPELLPEIKKVIIENAKLSKLGLIDVLFHKIDGLSKGEAKMALDVLATKVGVGRAKEWALKGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYW7</accession>
    <name>A0ABR3YYW7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">COG3</name>
        <name evidence="12" type="ORF">Cpir12675_004342</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000120">
        <property type="protein sequence ID" value="KAL1892933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048685">
        <property type="entry name" value="COG3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048320">
        <property type="entry name" value="COG3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007265">
        <property type="entry name" value="COG_su3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13302">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13302:SF8">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20671">
        <property type="entry name" value="COG3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04136">
        <property type="entry name" value="COG3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 3 N-terminal" evidence="10">
        <location>
            <begin position="136"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 3 C-terminal" evidence="11">
        <location>
            <begin position="300"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="9"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF20671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1892933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="756" mass="84857" checksum="61E901F7343A1C3A" modified="2025-10-08" version="1">MYDDQWYNFVPEATNKPTRTSGQPTRSHGRKPSLLQQPNISSDVRSSSEISRPVLAVVEDEEDSFPEPQVLRRAASSSDLIHPRQRFTVRKFSKRTTKASRLPALLLEGYTSADDEGESDCDEQLQEKSRNVYIAYQAQLTLTEGHLDNLISDTDDTLRLLESLTSSFKAVELQTTSFRSQCEDLISDQERLKKLSDEVGTDLHYYAYLDNATRRLNAPGASKLVDDSSFADIFRHLDSCIDFMSKHTSYRDAESYLARYQSLLTKALHLLETGLSNKLDKVAMNLAPQLNNTNSESAQHALSYDRFGEMTLESYSLVPNIHEVTCRIYDKTGIHKDDIIASEIYEGSAKNMFYTYLSIRDRHMRTIAHRDIEEYKTSQAQGVSIESASRKYIKQCFERAFNEVNLFAKIFHVLPRRSPDDDSVYAVLKSHQRFLVNPANMAPPGAAIQAGLHAAELRTICNIVGWLSNEYLMSDYDESDSPFSIFSREYAAALLSDHMWPFVERGFEAEVSKIITKAPVAPESLQIPKVVGPLPVSNAYPTVKVALALLDMFDQCMPKERSKQSATVFNIVRETIRALQRIETKMKATKGSSDSDVFMIKNLLVLRNQLVSLEFGDVRQQSTAGGGALGPIWDTINPQVWVGFLSSIMSAAPLPIWSRGLTGSATPVPPPAPALTQENMSEHLDELLRRAIYAFTGKWAAKVVEAEAKKDDGKTLAAIDVELDTLLENVFGNQREVMDRLKEAIDANVEMQKGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ17</accession>
    <name>A0ABR3YZ17_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">DNA replication regulator SLD2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_004066</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Has a role in the initiation of DNA replication. Required at S-phase checkpoint.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the SLD2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000107">
        <property type="protein sequence ID" value="KAL1893635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021110">
        <property type="entry name" value="DNA_rep_checkpnt_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040203">
        <property type="entry name" value="Sld2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28124">
        <property type="entry name" value="DNA REPLICATION REGULATOR SLD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28124:SF1">
        <property type="entry name" value="DNA REPLICATION REGULATOR SLD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11719">
        <property type="entry name" value="Drc1-Sld2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 8" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="27"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="162"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="282"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="370"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="27"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="97"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="389"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="438"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="456"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="494"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1893635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="519" mass="57985" checksum="E272C16675964440" modified="2025-10-08" version="1">MDPAERDKLDKQCIAIRAELKSWESKYAERHNGQKPSREAIKASPDIAAKYKQYNNLRDLLSGKRPKQKSPKAANSRPTEPHSVSPRKCKQAILVTPSKTRVQHFQTPTKTRIAQPDFLTPTTKRLASPEPPSTIGPTPQRDGRVLGLFDLMSDTEYKSPSKVGFADISTPQKRKLDETDDDSVFSRTRTPMSASKRQMLDSFLTPTKRLGGPASGSAIGTTPKSVSKDFSTPLFLKRRTATVIFDKETELTSPSRPIRLGRPQFTKGLSSLVASLRKVEEEAYEDDEEAMRATEAAEFEDLPSRPVHPSPPKFERKPLQQLTTPITGSEEPEDEYSVQDSLDNAADLSVSETILDSQPRLRLLSGFDDVNMYDADQEKTSKGRTSYTRYKKRKPKRTTRKVTIKPTIYQRPTDAAGDDPDVIPETQPQDPALLGPDSDGEFVDINDENVPPPLQKGHHGRKKKTSGLASAGTESDAMQAKKPQRKVNELAHANFKRLKLRNHGAKGGPSFNSKYRRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZD6</accession>
    <name>A0ABR3YZD6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cell wall assembly regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SMI1</name>
        <name evidence="4" type="ORF">Cpir12675_004140</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KNR4/SMI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000111">
        <property type="protein sequence ID" value="KAL1893402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009203">
        <property type="entry name" value="Knr4/Smi1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018958">
        <property type="entry name" value="Knr4/Smi1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037883">
        <property type="entry name" value="Knr4/Smi1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051873">
        <property type="entry name" value="KNR4/SMI1_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47432">
        <property type="entry name" value="CELL WALL ASSEMBLY REGULATOR SMI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47432:SF1">
        <property type="entry name" value="CELL WALL ASSEMBLY REGULATOR SMI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09346">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017023">
        <property type="entry name" value="KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00860">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160631">
        <property type="entry name" value="SMI1/KNR4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Knr4/Smi1-like" evidence="3">
        <location>
            <begin position="142"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="53"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="213"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="370"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="505"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="53"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="232"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="390"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="424"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="520"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="543"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="560" mass="61462" checksum="34ED9B45BCF1B06F" modified="2025-10-08" version="1">MSLGDAFKSFWHSMTSNDRHSNYDSPYRTGRHVPLDSARGLTSVATGFESRHDLSYSDDRSDFDSRPPFSPASPSGSYSPGLRSQSVRTNAEGFEVQSPGDVPMQAFRDGMPPAPPVSHSWRRIDAWTEEHYPELSDQICEGATRNDMNDLEHQLDSSLPADVRESWMYHDGQERGGMPTGVIFSNMLLDCEEIVQEWENWRTVNAEFLQRQAAMPPTPPARHSVSEDGGEPSSSKSNSPKSASRNNPNWRQDLISRQDCVPAGAIQRAYSHPAWIPLVRDWGGNNLAVDLHPGPTGHWGQIILFGRDYDTKYVIARSWAHFLAIVADDLCSNKWFINEDTMELKLREFKSTRVEPGYFEILRWRMDQKYGRRPPNRKSMAPTPRGGTPRSANTSNHTSPTGSPYMSPTVENQPSDSLRGRSLQRLSAASPLANSPLVSPSRPGYAKASPLARVTEEGDSGSATPNNSSSSSNIKNALGVTPPASTAAVPSKLLEIDSPVLLTDTAKKSKMSLPSTADGSETAASTKSTASSGSSTDDDSETENEKVVNKTDDGMKTIEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZG1</accession>
    <name>A0ABR3YZG1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_004103</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000109">
        <property type="protein sequence ID" value="KAL1893450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.130">
        <property type="entry name" value="Ubiquitin-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057501">
        <property type="entry name" value="DeUb_enz_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051947">
        <property type="entry name" value="Sentrin-specific_protease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46896:SF3">
        <property type="entry name" value="FI06413P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46896">
        <property type="entry name" value="SENTRIN-SPECIFIC PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25424">
        <property type="entry name" value="PH_35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="7">
        <location>
            <begin position="466"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="61"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="343"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="745"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="789"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="833"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="919"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1030"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="124"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="343"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="355"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="391"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="757"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="800"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="844"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="958"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="986"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="998"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1041"/>
            <end position="1052"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1060" mass="117757" checksum="EFFDF8747E6533C6" modified="2025-10-08" version="1">MSSTVNYGDKEARHGATKIVPGQAKSRLSSLNSQSHRSMNTLNTSQTEAIKKSYIEEFADMEETFRPHRTRNRRSNRNRTPSALGRTSPGSHDSASSDDELQVGSFGRKKDLESQSLHSRYRRERKEKSNPEARQDSEDELAEGHAPHSRDIIFSQARLVPANEGTHFAESQKMQDPRPTSPTTSAKNVEFSIQPTHNQPVQTVSYKWKFSVRAVVSGPHRIEIFDWAWPSTGPDADCVVPKPSPSKDKSLLDELDTAWAKVRIPKLQILKYARDSRYVLIIRCNEPGVESKLAAQFASSQEANRFVEAVGYSLPRKTRTLEIKEDYWLESCFRRMLVEQRAHQQRQTEQHSHAESSQTPRQAINQSPQNSVSHSTPPAPRNLLREQPKDTPSSSSLPTTSLRQTRSSGSILAFQGLLMERPRRRTRQIDTISLDIPKSSWTRDNPGWRERWKESLVYPRTGRDRATVDADDIERLDEGVFLNDNLILCYMRYLQQKHQGSLIARNLKVYFMNTYFFGVVKPTSKGASINYEGVQRWTNNVDLFEYDYIVVPINESTHWYIAIICHPGKLLPNAEVAVADEESEPLEDTIFTGDSQASSRKRPAGPHAPRIITLDSLGAPHSATCTVLRDYLYAEMAHRKNAKGEKALSLGITAKYIPQQTNYSDCGVFVLGFIEWFLKDPVGFTAAITEKNVPDCNFEPSELRNKIRETMFQLQAEHHAETLRLAAEKEALKLSRKAARLSRKALEDSLKTPPRLGSTTGSPVDGTGSSEPPASIAAFAKVTLQTNNTAPASPVRSKHVSMSSPTKPSVGSTLEKRKRESDLDALALVNHVDGAPSAPLSSSPHRDVTKPRPSSEESCTVRSEVETPKNLAHAPKRPRTQKHAQGEDDDDVEIVLSTTWKQQDTWKRPSIELKSVPIKIPAVGSSTPPHDHSTDSTSIPLGDSQGDSFLPDRKSEHNLGSPSGLPQDSKPGTSPSSFDGNATTSKKNPPQNNDNNKTFGSSPTDDSVSPFFTGHSSKYKITKKYAATAPKYGTNSALGLSKKPATSSATSSNTIIDLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z089</accession>
    <name>A0ABR3Z089_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_004136</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000111">
        <property type="protein sequence ID" value="KAL1893398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06609">
        <property type="entry name" value="STKc_MST3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050629">
        <property type="entry name" value="STE20/SPS1-PAK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012:SF27">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE SID1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012">
        <property type="entry name" value="STERILE20-LIKE KINASE, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="10"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="359"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="431"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="596"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="368"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="433"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="601"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="626"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1893398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="701" mass="77656" checksum="9F2A5FB21906A617" modified="2025-10-08" version="1">MSSEDVAKHYEMLEELGRGSFGVVYKAIEKATGETVAIKHIDLESSEDDIQEIQGEIAVLSTCASSFVTQYRGCFLRGHKLWIVMEYLGGGSCLDLLKAGVFPESYIAIICRELLRGLDYLHSEGKIHRDIKAANVLLSDKGKVKLADFGVAAQLTNIKSQRNTFVGTPFWMAPEVIKQDGYSYKADIWSLGITAIEMANGEPPLAHIHPMKVLFHIPKNPPPKLEGDFSREFRDFISQCLNKEGDKRPSAKELLRHRFIRNAGKIEALQDLIERRRMYINSRESRRSHPAFYQETLQVLSPNDIHDEWVFDTVKSTALPASMVRPPSDMDSVSHKPMENSMLSTEEAFRHLEINDASLQPLSPMNGTVRRSTMRRTTAAMGSVRRIRNVSGVMENEIGSVRHLPKKPLQPDLSFGNSGSTMRLFRRVPSDGSFVSQKQPGSLDPLTQQETNDNGKSSFPAPPELTSKEAVLGRRLFDKALDPSLVELHAQTSTLAKREALAKLSDALSYLDAIDPEGVYHFMRNVATSMSQDTKLNAAFLQPAGISNFASSAPAPTSASVKHPAADTPQGTVIIRNGVPPASFVYNTLDMTQAQRYTTPKPSSASNDKSSSGGGKNNSNISNSNAQVRNMQHNQASRTQPSDTGGSSSSGSVVWREKEKNVQELKYPGRHVVPGMEHCNQLSEVLYSRWVDGLRMRWPDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0D2</accession>
    <name>A0ABR3Z0D2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA-directed RNA polymerases I, II, and III subunit RPABC5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RPB10</name>
        <name evidence="7" type="ORF">Cpir12675_003831</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000097">
        <property type="protein sequence ID" value="KAL1894096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00250">
        <property type="entry name" value="RNApol_arch_Rpo10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023580">
        <property type="entry name" value="RNA_pol_su_RPB10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020789">
        <property type="entry name" value="RNA_pol_suN_Zn-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000268">
        <property type="entry name" value="RPABC5/Rpb10"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003089">
        <property type="entry name" value="PRK04016.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23431:SF3">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23431">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01194">
        <property type="entry name" value="RNA_pol_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005653">
        <property type="entry name" value="RNA_pol_N/8_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46924">
        <property type="entry name" value="RNA polymerase subunit RPB10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01112">
        <property type="entry name" value="RNA_POL_N_8KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00020813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1894096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="76" mass="8772" checksum="2614587E92E8FB3B" modified="2025-10-08" version="1">MIIPIRCFSCGKVTGDLWERYLDLIHDGVNDGDAMDQLNLTRYCCRRMIMTHVDLIEKLLKYTPDGRDAKKSQLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0I1</accession>
    <name>A0ABR3Z0I1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004024</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000105">
        <property type="protein sequence ID" value="KAL1893677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046734966" evidence="1">
        <location>
            <begin position="18"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="193" mass="21506" checksum="3FCDC6524DBEF645" modified="2025-10-08" version="1">MIPIATLALALASTAFASPLVTRTGEDIKPLEISNMEVSCVKTAPSDSLFHCTLNYDMNDPNVIDAKPSIKPKATCTHHWDWDGQTAEKGPQNSYTPSALECYSDGISRTIRSGLYHFSSPADIQLTLHSSYYKDLEAKLFVNLFYQHVTVAALESVQDTEMSKIWSYRSVQRFESPNVFLYPTTTKPDETAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1D2</accession>
    <name>A0ABR3Z1D2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Minor extracellular protease vpr</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_003952</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000102">
        <property type="protein sequence ID" value="KAL1893833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02124">
        <property type="entry name" value="PA_PoS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051048">
        <property type="entry name" value="Peptidase_S8/S53_subtilisin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399:SF4">
        <property type="entry name" value="CELL WALL-ASSOCIATED PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399">
        <property type="entry name" value="SUBTILISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046854072" description="Minor extracellular protease vpr" evidence="6">
        <location>
            <begin position="20"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="7">
        <location>
            <begin position="142"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="8">
        <location>
            <begin position="322"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="859" mass="93683" checksum="DC6507C5C6365C7C" modified="2025-10-08" version="1">MHLQTLFLTLLVTPGISLAQVHNYIVEFSKIHQSSPLLARDTDLRILQTYDSDVFRGASIESSVLTRRDILALEGIENVWINRMVTLNTEEVVTKFADDTKSPEYSQHVITGVSKLHDQGIFGQGIKIAVIDTDWPDSGLKTPDDDPFEMQFHGTHVAGILAGESPNWHGVAPNATLYSYKVFSSSKDTDEATLIDAFLRADADGVDIISCSVGSILGWSENAWADVADRLVKEKGIVIAIAASNDGAAGPFYGTSGASAENVLSVASVEGEISAQPAMTATFSLGNSTRKVKIGYVPSVVWFATSVVNWPIVPLNFNTSIEDEACTPYAKGSFNLTGKIPLVRRGGCPMKTKQLNLAALGAKKMLIYNNGGPMSALYTNNYTTQVGLIEESAGQSIIAAYSSGVKITADFSKGPKDVVGISRQYASLPSRFSSWGGLYDLKLKPDIAAPGGTIWSTLPTDSYGVLSGTSMSTPYVAGIAALYASVFGSRSTRGSKAGIDITQRLRSTAGSVHWWDQINPSYAPPIQVGAGLVNAERLFESKTKVTAKMMALNDTANFVGTHNFFITNNDDVDVSYTFEIQAAASIEMLDPWNKDLKTPMIKSFDKISPVNTPLVAAIPGDMTLGPGQSANLSVDFQPPDVKDSAVLPVYGGKLVIKTSTKEVHGIPYMGLAADLRKQFDNFWMDGWPRATITKQAVDIWNYTAWNNDVWNASMPFLSLETRAKWGTRQLRFDVYKPGFKESDWEYPPVVGSKGYLGSATYWKRSKNVFFDTTKNSSDPNDTFDFPELNMPRNADYTGYKRTFFWFGKLTNGSQIEPGKYSLRIAALKPFGEPELAEDWAISKTPEIEILGKYGPGPHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1L3</accession>
    <name>A0ABR3Z1L3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nucleoporin NUP37</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003839</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000097">
        <property type="protein sequence ID" value="KAL1894104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="623"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="710" mass="76154" checksum="0E6C73BA45356CFC" modified="2025-10-08" version="1">MSLAAPRIRRTAQNTQFTYQLSRRAHDVKTYPIFSPQGATIILYGHQNGITVVWRGGRRLKEKKVEPAPKETSKSKPNAEDAVMVLDSDSDSEQGDSNPEPTKPFVDQPEFEDEALNDPYPEIIQTLDLELGTSVLHIAVPSMTPTRTLEDGAFVGIEKLKTHMVFAVSCGTNDVYIVSVPLTPPSHESKARPELYKDLLADQTGAGLWGETLTLLTGQLQPSRGVAITVIKPKAGSKHPTKSKVVVASHTREAFGALRLWESTLDRIVAPAHGSLEAFQTEFLPHGLSTISFNSTHTSHLLAVSPQQGVRVYDFTLAPYAAEDLAPGSFPPQGSWVLSLFQPFTKGFPVRKPIVDAAWIAYGRAILVLLADGMWGIWDVDGVSPKSSSLLGKNKSGVIGGAVTQFSASGQIDGTNLLRAGAPDAKLPRSGAMSASSVFAPGRMSSVAGGISVTGIPGPLGSGADESVAMWINSWEHICVIPGILRFWDSQLRKHNGGGVNLFSGAQPTRMFKIHELSVGLMGEKCTALCAIAIRDKDKSGQEGQHGLPVELAVLGESRLVLVRESEDISTTGGGLVVRKKFGKRNNSTALVVDRPDKVPKLLFDLNPGKAGTIRSALNVPQGLNAGSKPDSKTAAFGRPSDPSMAEPVPSASLPFMDILDAAADTGQETSESRDIEVEMLDIMEIDRQLDTLEDFRGGSRKRVMFDGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z236</accession>
    <name>A0ABR3Z236_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003743</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000094">
        <property type="protein sequence ID" value="KAL1894266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF4">
        <property type="entry name" value="NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="11"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="186"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="291" mass="32090" checksum="4E7887A81AD22152" modified="2025-10-08" version="1">MPLIAQNTKPRIILGLMTFGPSKEAGTRIADIEEYKKCLDTLQVRGYNEVDTARVYIAGQQEAFTREAGWKDRGLTLATKIQYPMKDGTNTAENGLSSAETSLKELGTDAYRAVPFAETLGAIDKLHTAGKFVRFGISNFTAFEVAEIVMTCKQNNWSADDLPDDGRLANTSSVIEVYRARYLQDTTFKAMKLVEEAASKHNPSLIEVSLCWTVHHSALKVLDGNDGVIVAASSKEQIEQNVTNLEKGPLPADVVEATEKAWELTRGNGAPYWHKRMEYGYDTKKAVFGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2R9</accession>
    <name>A0ABR3Z2R9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Trehalose-6-P synthase/phosphatase complex subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TPS3</name>
        <name evidence="4" type="ORF">Cpir12675_003965</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the trehalose phosphatase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000103">
        <property type="protein sequence ID" value="KAL1893809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03788">
        <property type="entry name" value="GT20_TPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1020">
        <property type="entry name" value="Trehalose-6-phosphate phosphatase related protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003337">
        <property type="entry name" value="Trehalose_PPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00685">
        <property type="entry name" value="T6PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788:SF15">
        <property type="entry name" value="TREHALOSE SYNTHASE COMPLEX REGULATORY SUBUNIT TPS3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="TREHALOSE-6-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00982">
        <property type="entry name" value="Glyco_transf_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02358">
        <property type="entry name" value="Trehalose_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="15"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="38"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="83"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="907" mass="103067" checksum="7540C8E75549E2B6" modified="2025-10-08" version="1">MTVFIASLFLPKTVHFDLPGTPENAGRPADHQERKQSRALSQKLSTNPSLFNRTDITPPESPVEEALFDPFANEDGFVPYPSTPKASAPAPTDKSSPKWGGRKNQPISRADSPPRALLTEAARTLEKAKQLGRQGLTQPRALVRSESHDRVFAHANWHISNAEQGNGGLRNAAEAARREGRVDDFTWVGTLGMPTDVLEGTQQQQDIEDRLATEHDMLTVWCSDKDFDGHYSHFCKQILWPVFHYQIPDSPKSKAYEDHSWKYYVNVNQAFADKIVKNWKRGDVVWVHDYHLLLVPGMVRAKLPEAKIGFFLHVAFPSSEVFRCLAVRNQLLEGMLGANMIGFQIHEYTRHFLQTCSRLISAEATPEGLQLEDRFVDVINMPIGIDPVSLASHREEENVQSWIQVLHERYRGKRLIVARDKLDNVRGVRQKLLSYELFLNKNPQWRDNTVLIQVALSGSEDPDLDATVSDIVTRVNSSWANLAYQPVVYLKQDIDYAQYLALLTIADALMITSQREGMNLTSHEFLFCQDGKYFDEKKHGSLILSEFTGTSSIFGGVELAVNPWDYRQCSEAILQALEMPEEEKADRWNKLYDSVMHHTGEHWFTEFLSRLDRVYKEQHRRDQTSVPRLSMAALSNKYMKSSRRLFLLDYEGTLVSWGPVTQIIPVSPQRTFHILTDLLADERNTVYIMSGRRPEELDRLFKRVPNLGLIAENGCFLKDCGSESWTIIADTDQIRSWKEPVKAIMNYYLERTPGAEVEERRCSLIFHYKSADDYESAARLAQDCAAHINDACEQQRVHAIPMDGHMVVEPIDWTKSTAAQRVFSDIKKHVVEPLGPYHNSVDFMMVVGDGREDEKVFRWANNLKHEGIVENVVTVCLGSRSTEATATISQGVNGVLVALQKLSQLQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3C5</accession>
    <name>A0ABR3Z3C5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">54S ribosomal protein L28 mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_003383</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000079">
        <property type="protein sequence ID" value="KAL1895111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042831">
        <property type="entry name" value="Ribosomal_mL40_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39150">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L28, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39150:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1895111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="174" mass="20098" checksum="D68CFE59F863CBBF" modified="2025-10-08" version="1">MSLLPTMRGLTRRLITPFLPSVTPPATATQTQPFSSTIALLKKKKKGSMDKATAENMTKVRQLKMGLFARAPPTLRMARNRWLRHWTIHRAWMLHTRAVQEANKRELMRMQQGMSNACEELRKTDGPAGRNEGYLYRIAMEKANVYNNGAVPIEYARFQTETPAKVSWDHKWKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3T2</accession>
    <name>A0ABR3Z3T2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nonsense-mediated mRNA decay factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_003308</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a role in nonsense-mediated mRNA decay.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000076">
        <property type="protein sequence ID" value="KAL1895291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018834">
        <property type="entry name" value="DNA/RNA-bd_Est1-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019458">
        <property type="entry name" value="Est1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045153">
        <property type="entry name" value="Est1/Ebs1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15696:SF36">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15696">
        <property type="entry name" value="SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10374">
        <property type="entry name" value="EST1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10373">
        <property type="entry name" value="EST1_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Telomerase activating protein Est1-like N-terminal" evidence="4">
        <location>
            <begin position="74"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="DNA/RNA-binding" evidence="3">
        <location>
            <begin position="201"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="606"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="860"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="622"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="863"/>
            <end position="893"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU369098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="907" mass="100838" checksum="1C20E11507126666" modified="2025-10-08" version="1">MPTVVENAEVALAWKEACKLRKSLVKHIDRLIESNATANDKKTFDKVEDYVAKFRLSCMQIIFADFVYATENHVQRDLWEAQLHVSKLYRAVIRESRGQHVALRRIEKRYAGFLNLCQLFYEGYVQRLATAYELPVLANIAHRLNPSPKDKSLGGMIQPSDLPKELLEMAIAACHDALIALGDLSRYHLKLKGKMNLYESAVSFYSLANDLNPAIAHGHHGIGLASVEVSKHFLVVYHMYRAVVAQEPHPNAMNNLATEFSHLRDPNASLATKDPSPQQVLEIIFVRLHAYFFVGNEMPKRDELEQAFFRRLEEVLLAIKPDEFSNILCMAIVNISACAVAKEKPKPLFYQYIFAFNLRFAGYFAWIFTRRMYETYNLGISSSSGKPQLGVAKGRKEPFVLDHIADMSLRILRLYSAWLLSNQSELASQIKSFEKAITIFICQIARGLTTLTFFFQGHLENAAHECGGHLPISKYLLEEDNDIVQCPAMGAPTIDSILKNPDTEKPRQPFANYRKNRENLWTETISRVADILTSSQRYTTDPTFPLTYAVLPGRKLAYAVDDKILPHAKDFDLGTGPSSKFPVCVSAIEELAPSQPTTPMNKYVETMEPEPESFHPGKPAKSSESLPSPKTGNLELAPKETIVSVQKEMKPKEPPSLSIRTQVAPIPAPLSARNMSLSPILAPPASALAASHSHMMDDNSQPYSSSPLEGSRKIPALEWSSVYTPKPAGGAWKQLTADQYYSGPLRRSSQMGGASATASPLIGMQRVSTPAQNAEHRQQLLNTLLDGAASGITPASSPHLTSGYLQSMTPFQQSQQPVDPPPGFGNISSSTPFLHSSNIFQGTPEQLQPRNMVMASPTTMAGSQFESYQQQQQYMHTRQQYSSSLNPTENTTSNPPPGFSSGSYNPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z490</accession>
    <name>A0ABR3Z490_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">chorismate synthase</fullName>
            <ecNumber evidence="3">4.2.3.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ARO2</name>
        <name evidence="7" type="ORF">Cpir12675_003228</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chorismate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.5" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000073">
        <property type="protein sequence ID" value="KAL1895368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004107">
        <property type="term" value="F:chorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07304">
        <property type="entry name" value="Chorismate_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.150.10">
        <property type="entry name" value="Chorismate synthase AroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00300">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000453">
        <property type="entry name" value="Chorismate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035904">
        <property type="entry name" value="Chorismate_synth_AroC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020541">
        <property type="entry name" value="Chorismate_synthase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00033">
        <property type="entry name" value="aroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003793">
        <property type="entry name" value="PRK05382.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21085">
        <property type="entry name" value="CHORISMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21085:SF0">
        <property type="entry name" value="CHORISMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01264">
        <property type="entry name" value="Chorismate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001456">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103263">
        <property type="entry name" value="Chorismate synthase, AroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00788">
        <property type="entry name" value="CHORISMATE_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00789">
        <property type="entry name" value="CHORISMATE_SYNTHASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="398" mass="42604" checksum="94ECB4F8DCBDE08E" modified="2025-10-08" version="1">MSTFGSVFKVTTFGESHGKAVGCIIDNPPPGLSLTEADIQPQLTRRRPGQSSITTPRNEKDRVTILSGCEFGRTLGTPIALSVNNEDQRPHDYGNQTMDKYPRPSHADFTYLEKYSIKASSGGGRSSARETIARVAAGAVAEKFLKESYGIEIVGFTSSVGPVELIEETPEFPSRSSNPKLLNLVNTITREQVDKFLPVRCPDVEGTLNMEDYISQLRDSQNSTGGTVTCVIRNVPTGLGEPAFDKLEAKLAHAMLSIPACKAFEIGSGFAGCRMVGSEHNDVFVKDENPAPGPEGANALPRPALTTKTNHSGGIQGGISNGAPIFFRVGFKPAATISIDQTTATYDGISEGVLAAKGRHDPCVVPRAIPIVEGMAALVIMDMLCIQQARHSMKNLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4G4</accession>
    <name>A0ABR3Z4G4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003214</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000072">
        <property type="protein sequence ID" value="KAL1895525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="312" mass="34016" checksum="59AA71037155970D" modified="2025-10-08" version="1">MSSMSAGSTKLSKRQRKKLAAITRGLGSQTAGATRTAKQPKLRLPGSLSKHITDALWNAVEAQAEYLGLPKFGSDEDIYAKVGENAARGSLVHDKVADVKISTSHRKAIRRSEVASQGPKQTSDVLISIPLGDTSSEGLSSNVLPPKPSPEFDIDTAAVTGNSHIIMESQAIPQPSSDVFETQPHPFDNMPRQARRRMVAIEKQRNTLRRLRGISPSQPEPEDMKQELEAWALAYDRKMASSSKEGRRMGKKVLGAGPSPKPKASPKPKPKPKPKPKPKPKPKPKPKSKTKTIKKKKAEGKAKKEHKNKTGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4H9</accession>
    <name>A0ABR3Z4H9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003368</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000078">
        <property type="protein sequence ID" value="KAL1895139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="694"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="883"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="143"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="447"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="467"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="528"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="694"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="780"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="883"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1023"/>
            <end position="1054"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1410" mass="157250" checksum="6C4F91C83AB97827" modified="2025-10-08" version="1">MTGPPPPPPPNGPNSRTTQTGDSSSSRLPPGNYDIFVIPPHSAGSGFLYLPSLNTNMNSFAAGFSCALIMVAGFQSIGPMLQSWLNGSYAMVNFTMILALFLVGAGSWYIGQVQSRAFTGAKPTMGASYQSSASGGPRPTQAPPQNNQYPQQESYSQQGHYQYERESPREAAPQAATFPSSPPREPTPPPQPREPTPPPPSPPSRESFPPPPREPFPPPPREPTPSPREPSPPPREPTLLREPTPPPHRAPSPTIRQASPPPRPIFSTPRRRRDVPSSVDHAFPSTPTRAPRVVKSPTPLVFESQSRPMNPHVESEPESPVKTTPASHRKTRQHQHDYAFDFGHDGEFDTKPGQPTRSASKSPVKKAISRSEGKAYTKSTPKSVSKIDKAADYVVEAKPEPKAVKKPIKVEKIESPLTKAKKSKKVVKPPSPPPPIESDYGSKPELEPELDIESELEPEPEPEPPKPKAKKTKIIKVKKAKVAKAPEPKPEPESDYDDNMMGYKENSEPEPPMAYESESEQELAPKPPKVKKVKKVVKVKSKVKAEPPTKFVEPEAESEPEPPAAPEPAVTLKVKKAVKKESKVSAKSETKTKVAAKSVVTAKIAYEAPSSPTPVQNIKSKKGITHIPEVTYAAPAATSLMSSRPVPLPEVRVEANVSIQSPRPISAPVPLPQMVEPVAASSPVSAPAIAPVAVPIPAPAPAPAPAPAPAPAPVPIPAPTLAPAPTPAFDPAPAPAPAPAPAPAPAPAPTPTPTPAPAPAPTSSPIPTLTSRPNPLNAWERAREETRRKEEVRKAKEEEQRRRDEAAKRLQELRDKEAREREARERELRERKEKLERGRQERERAAKLKLEQEKREKEAKEKREKERLDRLLREARERETLERLKKEHEARERERERMVREARERESKLREEREQEVRKREAEEKAARDREERQRLLRERREQEQHEREKREFEERLSQRRREDEEKERLEREKREKERLEKERRDKEEKEKERLEKERKEKERMEQEKKEMEERSRLAKLQEIADRERRECEFKERLERETAEKLRNEEDKNSRAGGYAYSSVGEKTRIWPNGKPSVAKSTVSEPPTASPNSAAPPPTTHHPSHNPRTEYHYTESPRQPPSAAGKASMRPEETYSYRPYDQPKKPTPRKKSVSDMSDGSWAPSQSTSRTTPPPSFRGHYTTPNPNKISIRAVYMFLNQFSKTPATQLISGQGPVTDGLVLRMTTEGLFIDDDIRGVPQREWDVKAWTLKHMEVWCPKHCINPSAATPSGIATSSGPSMLNKLTGARIRPERGGTRILQGADADTYISELLTACKGCCSMGMCESQFADMTIPSPSGQSGDWRNKGLHVLRATIRDQEGKRYLVVVDEEESWKLAIGLQKLRQGSQVRALGIVGLGASEMRGTLEMLGWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5B3</accession>
    <name>A0ABR3Z5B3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Membrane fusion mating protein FIG1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003043</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000066">
        <property type="protein sequence ID" value="KAL1895821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033481">
        <property type="entry name" value="Dni1/Fig1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28092">
        <property type="entry name" value="FACTOR-INDUCED GENE 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28092:SF1">
        <property type="entry name" value="FACTOR-INDUCED GENE 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12351">
        <property type="entry name" value="Fig1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="222" mass="24048" checksum="66E68E7A7D876177" modified="2025-10-08" version="1">MPGIFLISLYYKSYEADPDTAQVDYNVHTAIANIAGDARLQARVGFFGICINPDGGSWLCSNNATALAKEISIDQDPLNLVWLASQFKDMIVFPYLIIIAVIFAFICFLLLLTFPGWQDGATSESGSEREIKTFPSRAVSQIALTIIFISSVFILVSVLWQHTASVAASVMTQSMANGSVKSGVGTSAMVMGWFAFALLIIVTIGLLIMILSIGLIHELITN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5H8</accession>
    <name>A0ABR3Z5H8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Abscission/NoCut checkpoint regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000070">
        <property type="protein sequence ID" value="KAL1895580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46603">
        <property type="entry name" value="ABSCISSION/NOCUT CHECKPOINT REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46603:SF1">
        <property type="entry name" value="ABSCISSION_NOCUT CHECKPOINT REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22586">
        <property type="entry name" value="ANCHR-like_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57845">
        <property type="entry name" value="B-box zinc-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="296" mass="31828" checksum="1E6A02CDDF3FB3E9" modified="2025-10-08" version="1">MADRNDMDELLNRLKALKPGTAAAKDAKPAKSSLSAFAPQKSQTSREDSLAARLKTLRNSAAANVPSSDSSPSVQKHTDHSTPQKSTSKSSNLGLIEGEGKEATQVLSKIDGPTPHHSEKERIKREIEETLENELPNLDTPCMNSRNGDSLELPSVPLELPVTSSLLCPTTDVDSVAARLLALQTPSSPPKAAATAETNTLGLPSVPTGISTKFKRLATKTDYTDEDADTWCIVCLSDATLQCLGCEGERLQIYCAECWSEMHLGPMASYDDGTHEAIRFVKPRKEEKKKVAIGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5J2</accession>
    <name>A0ABR3Z5J2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetylglucosamine-induced protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_003179</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000071">
        <property type="protein sequence ID" value="KAL1895541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022036">
        <property type="entry name" value="DUF3605"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35020">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-INDUCED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35020:SF2">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-INDUCED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12239">
        <property type="entry name" value="DUF3605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1895541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="233" mass="26843" checksum="883F9E1873B5C7AF" modified="2025-10-08" version="1">MGNALSLIYPISAVNDDTDPRYVIPDVDMTKVTLTESDRWVLRFRSDAEFPTLSWETLGANIEQNDLNGLQRTPSELKRYLKWGQDTREVYGSVMEYLLYHRLPAAWGRPPFTFVSDIPFSEESDYCILTNEWPYALDQGIVHVVVWTRTPIETDNVIGDMTPRSRAIVDAFIERMFRAKVGDQNVLWFKNWTALQSVRSLDHVHVLLRNVDQGLINEWTGGVVTPHMLALQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z650</accession>
    <name>A0ABR3Z650_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase subunit AC19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RPC19</name>
        <name evidence="8" type="ORF">Cpir12675_003305</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000076">
        <property type="protein sequence ID" value="KAL1895288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07029">
        <property type="entry name" value="RNAP_I_III_AC19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00261">
        <property type="entry name" value="RNApol_arch_Rpo11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009025">
        <property type="entry name" value="RBP11-like_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008193">
        <property type="entry name" value="RNA_pol_Rpb11_13-16kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033898">
        <property type="entry name" value="RNAP_AC19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022905">
        <property type="entry name" value="Rpo11-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13946">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I,II,III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13946:SF28">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13656">
        <property type="entry name" value="RNA_pol_L_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01154">
        <property type="entry name" value="RNA_POL_L_13KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RBP11-like dimerisation" evidence="7">
        <location>
            <begin position="51"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="133" mass="14843" checksum="67E0B966510AD2E7" modified="2025-10-08" version="1">MSTADERMQSEDVSMDDAPPAMEVAAEEAEETEEELPQRVRILPGSDDRAASFEFLDEGHTLGNALRWVIMKNPDVEFCAYAIPHPSEAKMNIRIQTYDGFAVNALRKGLNDLAEMCDVMADKFTNSVQGTRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z668</accession>
    <name>A0ABR3Z668_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">T-complex protein 1 subunit zeta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CCT6</name>
        <name evidence="8" type="ORF">Cpir12675_003042</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000066">
        <property type="protein sequence ID" value="KAL1895820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03342">
        <property type="entry name" value="TCP1_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012722">
        <property type="entry name" value="Chap_CCT_zeta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02347">
        <property type="entry name" value="chap_CCT_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="544" mass="59179" checksum="05BEE247D5DDE5A0" modified="2025-10-08" version="1">MSAAQLLNPKAESRRRGEALQVNISAGEGLQGVLKTNLGPMGTIKMLVDGAGQIKLTKDGNVLLREMQIKNPTAVMIARAATAQDDICGDGTTSVVLLVGELLKQAQRYISEGLHPRILTDGFEIAKMETLKFLDDFKLPREPSRELLLNVARTSLATKLNSTLAAALTTDIVDAVLSIYEAPSKPDLHMIEIMKMQHRTAADTKLIRGLALDHGARHPDMPKRLENAYILTLNVSLEYEKTEINSGFFYSSAEQRDKLVESERRFVDAKLKRIVDLKKEVCGNDPKKSFVIINQKGIDPLSLDVLAKNGILALRRAKRRNMERLQLVCGGTAQNSVDDLSPDVLGWAGLVYEQTLGEEKYTFLEDVKDPKSVTLMIKGPNAHTIAQITDAVRDGLRSVYNVIVDGSVVPGAGAFQLACASHLKSDAFYKTVKGRAKWGVDAFADALLIIPKTLAANAGHDIQDSLAKLRDEHDEGNAAGLDLVTGEAMDPTLEGVFDSFRVLRNSIASSTSIASNLLLCDEMLKARQMGRQGGPGPGMDGPEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6F6</accession>
    <name>A0ABR3Z6F6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000067">
        <property type="protein sequence ID" value="KAL1895807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="193"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="284"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="380"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="422" mass="44542" checksum="4EBFD408686D6F3E" modified="2025-10-08" version="1">MASRRVSQGKVPSYRNTLAIVPSPVSSFSEDDPFSSYYHPTSLPKSSPMAPAPALPAKSDRRISRLIIPTIHASVPPAAIDTTSTTMPHDVYLSSEEDASSTPGDASDYNWDSDSEEIFSPPATTMPVTARMISVVYSGKPSMVQLSSRRSPSPRVCIRQDSGSSISSSPMHYTNSSVLSLPSTGSETCGARSPSVPSSSSSTRPISMFVNARPTSEFLPSSRTLPRTRPSFLSIDPYATSAPPSAFSTDLTVSPVMQQDLNSPFMSAASASSVSLASSTATTAAPSCSSATTTATVESSPAPKTPSAMFKRTIDLVRKKSRPTLNAAFVSSVRDSMIPETPQLPQTPQLQVQHELTAPSTPNTLPITNNDMLRVAKRNSSSPHTASVSSTASGSASPQPVLSSAVKTRILSLARLRNSVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6I0</accession>
    <name>A0ABR3Z6I0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial</fullName>
            <shortName evidence="7">Glu-AdT subunit B</shortName>
            <ecNumber evidence="7">6.3.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_002882</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>L-glutamyl-tRNA(Gln) + L-glutamine + ATP + H2O = L-glutaminyl-tRNA(Gln) + L-glutamate + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the GatB/GatE family. GatB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.-" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000061">
        <property type="protein sequence ID" value="KAL1896236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00121">
        <property type="entry name" value="GatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017959">
        <property type="entry name" value="Asn/Gln-tRNA_amidoTrfase_suB/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006075">
        <property type="entry name" value="Asn/Gln-tRNA_Trfase_suB/E_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004413">
        <property type="entry name" value="GatB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017958">
        <property type="entry name" value="Gln-tRNA_amidoTrfase_suB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659">
        <property type="entry name" value="GLUTAMYL-TRNA GLN AMIDOTRANSFERASE SUBUNIT B MITOCHONDRIAL AND PROKARYOTIC PET112-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659:SF0">
        <property type="entry name" value="GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02934">
        <property type="entry name" value="GatB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="GatB/YqeY motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01234">
        <property type="entry name" value="GATB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aspartyl/Glutamyl-tRNA(Gln) amidotransferase subunit B/E catalytic" evidence="8">
        <location>
            <begin position="96"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1896236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="642" mass="71208" checksum="594FA0E5E0539C08" modified="2025-10-08" version="1">MHIQRVSLRHITPYAAYARPSRHLSAFLTTSVITHRVSLHTEALHEEALSEQPGATATTIVSAPLRKRLKDEAKRQKQAKSNFKASTQTVDGWELTVGVEIHAQLNSPTKLFSAASVAPQPSSHNCVNQHAAPFDLSVPGSQPLFQPPVLIPAIRAALALGCTINTISRFDRKHYFWWDQPAGYQITQYYEPFAQAGHIKLQARDGIAAEDGESTTVRIKQVQLEQDTAKTLSQPGDTHWIDFNRSGAPLIEIITEPDMHHPRTAAVFVQKVQALLKAFDVCVVGMESGGLRADVNVSVRRTNNLANTPLGVRTEIKNLSTIKAIEDAIIAERNRQIHELEAGGTIASETRGWTLGFKETRRLRGKEGEVDYRYMPDADLPPLIIAPSLIQELRQSIEATPDTEIDMLMSKFGLKLKDALALTASANEDRLEYFYNVVDALHVLQAKSSPIAMGDNFIDHKLSLLTSNWVLHEFGRLAKAEKGLGATAGAATATATPDKMADLVSIDYLAELLHHLHNGRITLGVAKEVFFIIFLDGLEVENTSGNSPRRIGLSEYLEKHNLWFTEIGALQYRELAEKAISNNAPRSHELLKTNEPPKGRVMWLLGDMLRNGPLENMVPANAEKALREVLAELRDAHLREER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6Y2</accession>
    <name>A0ABR3Z6Y2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N19m, NADH-ubiquinone oxidoreductase 9.5 kDa subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">N19M</name>
        <name evidence="2" type="ORF">Cpir12675_003012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000065">
        <property type="protein sequence ID" value="KAL1895972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22903">
        <property type="entry name" value="NI9M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039961">
        <property type="entry name" value="Nuo9.5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38488">
        <property type="entry name" value="OXIDOREDUCTASE 9.5 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G08980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38488:SF1">
        <property type="entry name" value="OXIDOREDUCTASE 9.5 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G08980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="78" mass="8637" checksum="C294284D8BE383D6" modified="2025-10-08" version="1">MSHPTPRFFAAPLTFMRWAIRERPAYFWSLAIGALGPAFIVAVPPLRQAVGDVNAARIPVTYPIPTGPRKQLTGFDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z771</accession>
    <name>A0ABR3Z771_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Essential protein Yae1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_002837</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LTO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000059">
        <property type="protein sequence ID" value="KAL1896433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019191">
        <property type="entry name" value="Essential_protein_Yae1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052436">
        <property type="entry name" value="LTO1_adapter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28532">
        <property type="entry name" value="GEO13458P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28532:SF1">
        <property type="entry name" value="ORAL CANCER OVEREXPRESSED 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09811">
        <property type="entry name" value="Yae1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Essential protein Yae1 N-terminal" evidence="3">
        <location>
            <begin position="20"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="70"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="180" mass="19351" checksum="99EC1C81C35C0A8A" modified="2025-10-08" version="1">MDDIFEGAFNLEDEIYNKAYEEGHADGIRAGKVEGRSFGMARGFDKFFEAGKLFSKAVVLGTRIAATPPGTANQAPDPSTPTKTASAQDTTTALTITAGSTAFAASEKSIPSLPPLQSNARLEKNIVALYDLMELDTLSTDNSDEAVNEFDDRLKRAQGKAKIIDRMLQSRPKNQAVSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7W1</accession>
    <name>A0ABR3Z7W1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carbohydrate kinase PfkB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002787</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000058">
        <property type="protein sequence ID" value="KAL1896450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01943">
        <property type="entry name" value="MAK32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034094">
        <property type="entry name" value="Mak32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47098">
        <property type="entry name" value="PROTEIN MAK32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47098:SF2">
        <property type="entry name" value="PROTEIN MAK32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="2">
        <location>
            <begin position="365"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="444" mass="48490" checksum="A073F1046A40D688" modified="2025-10-08" version="1">MSSTETIKEGAGPDQALQSDEGQDHQDRHLTTQPTAVDDGGRAESEPQIDFVTLGMFIIDEIEFPPPKPSVKNALGGAGSFAAMGARIMSPPPKSQSVGWIVDQGSDFPPALTGLIQLWNSSVLFRRDDARLTTRGWNGYGDVETRGFRYTTPKKRLTGRDLTPAMLLSKSFHMVCSPVRCRELVSEIKALRKELQTSHNETCAKPFFIWEPVPDLCTPENLLECTRTLSYVDICSPNHAELAGFMGETGIDENGDISQEAVERSCEQLLASMPLQSFSLVVRAGRKGCYVARNGGRKGSSINWRTTKPARQKKQQHALSSMLRPDTDMFSLFEHLTPDNEGCIDREEIEIDAGISRWIPAVHSDPSQVVDPTGGGNCFLGGLAVALARGHNVEEAAIWGSVAASFAIEQVGVPTVVGDGSGNETWNGVDVQDRMLEFKTRILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8N3</accession>
    <name>A0ABR3Z8N3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translation initiation factor eIF2B subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eIF2B GDP-GTP exchange factor subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GCN3</name>
        <name evidence="10" type="ORF">Cpir12675_002778</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000058">
        <property type="protein sequence ID" value="KAL1896441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="entry name" value="Translation initiation factor eif-2b, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1070">
        <property type="entry name" value="Translation initiation factor eIF-2B, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051501">
        <property type="entry name" value="eIF2B_alpha/beta/delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042528">
        <property type="entry name" value="elF-2B_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45860">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45860:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1896441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="354" mass="39171" checksum="0BF17AFB1724228F" modified="2025-10-08" version="1">MQDPLQIRPRTAEFDIVGCYNTLLAENPDLTQPVAAIEALIAMLNASSSSTVYETLESTTRYANLLKEAVHNPLPLTAGTDLFQQFLLSSLKQQEGSVKDGLAVSFDALRAALVQNGSLFAQRAREARDRIAAAGWRFVRDDECVLTHGASRTVSTLLIKAAKESRSRNNGTVRFKVIYVRDAWRVNESDRIVNQLRAEGIHVAEIPSAAVAHVMAMLRQVHVVFIGAEAVTQDGGVISRLGTLQLARLARHASPPIPFYVAAEEHKFLRRLPRYQDDADLGCSQSLLDFTTDKSSHQPENPIDWTDHTYITNLITENGVKSPSYVTEQLIEIYGTLTPQMILDKVQFGITSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9F6</accession>
    <name>A0ABR3Z9F6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transcriptional activator hap5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">HAP5</name>
        <name evidence="10" type="ORF">Cpir12675_002795</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NFYC/HAP5 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000058">
        <property type="protein sequence ID" value="KAL1896458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22908">
        <property type="entry name" value="HFD_NFYC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050568">
        <property type="entry name" value="Transcr_DNA_Rep_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252">
        <property type="entry name" value="HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252:SF8">
        <property type="entry name" value="NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="9">
        <location>
            <begin position="78"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="200"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="200"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1896458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="287" mass="31220" checksum="A0E3AB6506855926" modified="2025-10-08" version="1">MDAQSTTSAPAEPTREQVVYDTTLGGHYGASAAIASQGLGPGEIYTGPWANVPQGLNAPYRDIMTTYWQHTIDHLENDNHDYKIHQLPLARIKKVMKADPDVKMISAEAPILFAKGCDIFITELTMRAWIHAEENKRRTLQRSDIASALGKSDMFDFLIDIVPREEATASAKRSNTQASAAQAQAQAQAQAQAQAQAMANVTTQSSQLPSTLTTPGASATHMSPSDYAMGTHNLGADQDYRQSSVMYSGPTAPQYPQAQNGLYGEIDGIYYTPMPAQQGQMSQDDFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAT4</accession>
    <name>A0ABR3ZAT4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosome-interacting GTPase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RBG2</name>
        <name evidence="5" type="ORF">Cpir12675_002724</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000056">
        <property type="protein sequence ID" value="KAL1896629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01896">
        <property type="entry name" value="DRG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1070">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045001">
        <property type="entry name" value="DRG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031662">
        <property type="entry name" value="GTP-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006074">
        <property type="entry name" value="GTP1-OBG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43127">
        <property type="entry name" value="DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16897">
        <property type="entry name" value="MMR_HSR1_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00905">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="3">
        <location>
            <begin position="65"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="4">
        <location>
            <begin position="292"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1896629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="371" mass="41218" checksum="B2C821CE3ECC4B2D" modified="2025-10-08" version="1">MVNITEKIKEIEEEMRKTQKNKATEYHLGLLKGKLARLRAQLLEPGPGSGGGPGAGFDVSKSGDARISLVGFPSVGKSTFLSKVTKTRSEVASYAFTTLTAIPGVLEYGGAEIQLLDLPGIIEGASEGKGRGRQVISAAKTSDLILMVLDATKRAEQRALLEAELEAVGIRLNREPPNIYLKAKKAGGMKITFQAPPKAMDEKMVMNILRDYKILNCEVLVRDENCTVDDLIDVIMKDHRKYVKCLYVYNKIDNVSLDFLDKLAREPHTVVMSCELDLGISDVIDRCWEELQLVRIYTKRKGIDPSFDEALIVRSNSTIEDVCDRIHRSLKDTFKYALVWGASARHIPQRTGLGHTVCDEDVVYICSGWRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAV6</accession>
    <name>A0ABR3ZAV6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Altered inheritance of mitochondria protein 21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002216</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000040">
        <property type="protein sequence ID" value="KAL1897790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021582">
        <property type="entry name" value="Aim21"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11489">
        <property type="entry name" value="Aim21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="607"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="693"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="840"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="533"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="712"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="724"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="854"/>
            <end position="878"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="878" mass="94568" checksum="40F884AA685E3CE9" modified="2025-10-08" version="1">MSTASTMGTPLVPARPSRSLAKETPKVPPRPSCSKVRDLSPDDRFAPSPLNEGFSKSPKVTRFSPTKDVTEFTDEPNLDNDTLSLSRPAMARMPSEVGDEGIEYGMAEKIEEDHQHHKTSPAPETRTVGDLELQAPRPSLPAKVDAVTKTTSEFAASLGLNKSAGSDIATVGSLRKKLSSSALSVDGAPLTEDEHGIPEIGRRVPMIPNAGDVQAPEDSDAPNANSRAQSTRGLPPGSYGLHSHGVFSTDKLETEYYEKRPDILQKEQKAASYNPHQAEYARSSADLNKIVNETHADDGGPTFGPPEEIAHEVQKELVAQNSPENSRAQSPRAIRNARISMMGSNSVHVDRNMPEANTDAEEVPILAPDMVAHDSIGHANTPAIEVERLAREEQARVRSAASHNTNMSYSNSPIPEIREEKVYEPLFNDEGSETKKETAEVHSHQQKFPSKDIWEDAPSSVHYTAEVNNPVDKDDGDKNPAIAEAEKINNDIKDKGGEEEETQHEEPFTASKSASDDGAANEPTNPALAFAKLQEKLAEDDAKCREGSPHHTHNFIPRGLGMHPKSPGFSPLASDAFRPTSAPRFPSRDIWEDTPDSHMIITTVDGDHEIAPGTQEADSPILDSKPGLPFVPARPSSSKPPIVGRSKPKPAASDRPKPAVPPRPSVMRPVGGKIAALQSGFMSDLNRRLQIGPQVPKKEEPAAPASVEAVPETEKAPLADARKGRARGPQRRAPAKATAPVASLGVEDVPVLEFSISKPQMLWSIEANGNIGFEGTVSKCEEAIEAKEKVASEAEKATDIEKTLDIEAIAAQTVATELAGIEAIKKEEKRDKVEVEAVKEAVEETNPVAATPEAEAKETKDEKSGDGEETEKIEAAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBK7</accession>
    <name>A0ABR3ZBK7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002074</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000037">
        <property type="protein sequence ID" value="KAL1898056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055589">
        <property type="entry name" value="DUF7165"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23749">
        <property type="entry name" value="DUF7165"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="61"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="464"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="702"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="739"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="852"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1004"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1206"/>
            <end position="1368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="474"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="706"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="739"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="780"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="800"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="852"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="882"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1011"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1236"/>
            <end position="1249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1258"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1306"/>
            <end position="1327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1394" mass="151182" checksum="5181B253CCBD4294" modified="2025-10-08" version="1">MDAVTVVTYEAELESNSAQALAPMLASTSASSSVPSSASASRQPSPKLHSSRQKIGPESQGPAIHRLPDEIIQQIITAADPNTFASLSLLNRRWHRISQQASLYALKLSQCLSFVASHESFCPHSARADDLPRLRRLFALQAKQNLFDAYLRPSITEIKLISTTFGSASAPAGEGLQFCPSPQGHHILAYNSSRIYVIDVRNRDAKVVRELATLRRPRSACIKDDGTLLAVLSTESQIDIYDLTQSPPSRKQSLFPDNPPRTIALSPCGAILATAYEGGIEVLDLHSDALVTGRRAVKCDTVDSLAFSFDGIQILGTTLNSNSAPPSTVVITAPYYDPNTSTEGSSSSLWTTSILFPNTSRDCSHSVLIQHTSQDEAAYAFTYDRNFETFRAVRVDDLRSSTTYFTGPLPHHQPNADAKIMPCTIPAATYYGDLVSSGFSCRDVWVYGVPDDLDAIPRFLSKTQAQDRPGGSLGSKNSSVSNRSSPGPASQVPQWQKLFDKHPNPNTFVRGFKIAELQGVSNVKFVQGFGGPNRIQERLVIAARSATVDIDKDDVNFVDGGRIMLVDFDYSMNNGVTKHIEIELGPLEAEVLEEEVRDLDTEVDIVRRRTVARNNGGARSSLLRISTTPATLGSTQVSPTFLSAPLIEASLQDIADDDDDPLVPRRLNASAMSLSRVASPHINNTLSFDADLWEALDAPYSHQNPRSTNTLRRAATAADASRRLRAATTPRVTYRRANGRYEHPHESDADNWVPPPPPYHKDDPGSVPNFMRQPAITPLPSGSHTQSPSSDALNLPTIEGGNTPSTAARSSPTVASMSTISPIALSQPQIAAVTSVEHIVDDTTPVQHLQLSQFAGGQSLTGRRTSTPTTMDEARMAPRTDISGTSYPSPRSASTPGLRNSQSRQLHDTERGITQGPRLMGVRMSLDEGSMRPYSSPENRPFGSRHSLNSGPFGRALSQDGRLFGPRLSLDERFVSTSDPFRGQPHSSRRSVDARSMFPPIVTRHRPAIPSSGTRAVSITSQTRSVSMPEPRSSIPPQSPPMPIGSSTFSPGGSDDYDPPAVWMTPRPGTSSFATFTETPDARQPLDNQAMLGEISTLSFPSHPLTSLRRTVLPYLNVDSSQFKIPRVPVASRSRVEPPRSWSTILPPLPPYSHSSHSPHSRSYSGNLPISSSSTSMQFTVMSDMPLMSTSTPTGNLIVPDTPLLISTPSGITGGADSTGPSDVQPRPEMRIHAPVAHRPRPSGRRGVARRLEDSLESRNSSSSSRDLAPLPVFPPIPGQSEQMNSASARHLSTWLTSSSKLRNKSATAIRRTRSNASRASRSAAINVRGLKHNKQKEQKKTLSTASTAGARRKKKSRDGDDGSVGTWTDITREFTPWVGVSASDRDGKKCLVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBT8</accession>
    <name>A0ABR3ZBT8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002257</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000041">
        <property type="protein sequence ID" value="KAL1897757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF10">
        <property type="entry name" value="ABC TRANSMEMBRANE TYPE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="360" mass="40750" checksum="086846C8F4AC841E" modified="2025-10-08" version="1">MSESPPHKAMRRSRTHQSPQDSLQRDGYSNSSNRNNNDDDEDQQMDNIAATMDLAETISLTESIRGHVEEAGLRYHAYHAGKYPFPNDVVEQDRDDLIHHVLETICGSVYFAPVENMLRNDGGRALDIGTGTGAWCLAMADLFPQATFVGSDLSPIQPETVPPNVQFVIDDFEHEEGWADDPETYDYIHARRVLITVYDVATLMKHAFDHLKPGGWIELQEFTNTIECDDSSYTEETTYRVRDFMQLLGQGLAAIGTDIHASNNIEQHLTAAGFTNITRHQFKVPVGRWPKDDVKSSCGEMHRESMHEGLVGLARKPLRALNWTNLQTEMLLVEVRQHLNDSSFHVYMVFNIICAQKPYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBV4</accession>
    <name>A0ABR3ZBV4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_002351</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the INSIG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000045">
        <property type="protein sequence ID" value="KAL1897495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025929">
        <property type="entry name" value="INSIG_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15301">
        <property type="entry name" value="INSULIN-INDUCED GENE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15301:SF3">
        <property type="entry name" value="PROTEIN NSG1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07281">
        <property type="entry name" value="INSIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="253"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="173"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="179"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1897495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="342" mass="36880" checksum="34395CB203A23EBD" modified="2025-10-08" version="1">MTDQSVPLLFRPIPRRPFLPAFSSPTPPPDPGANDDGAVGLKSTARFLQTFNTDAAISAPETPSSPALSRSGSSFFNLTLNLAGMGLGSASSNSFNNSFSQSNNTSSTLGGIFSPSMTSMDRFFDDSVPSSPWENGPQSPVWRQGIDDSTYEVIKKRSGLRYQHCNASAIDATTKPMDTNTNGTTNTNGTTETEPSSGSSYSIFAWFSEASLPLPLRIAILFVLGAAYGDMVSGRNATRTSNSLSRQILDWEYLMIWGCIGIACGILFRYADAVWDMVFREAEDEPMPSEIKTHGHLLQTASHGTLKEWTLVVRSIAAFVGIVFAIVSLSSIMLIGTSRLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC91</accession>
    <name>A0ABR3ZC91_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001998</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000035">
        <property type="protein sequence ID" value="KAL1898291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="88"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="590" mass="65809" checksum="DEE5DA3984533CED" modified="2025-10-08" version="1">MFSFKNTIESKPSNENLTKVSSTPSSIESTSNSTTSHKFSHTISLSRRLLRKLGYKPFTSKPLPTPHTGNSSYSSPNCSLASYVVVGWPSLPLELQIEVMSYLSLEERVRFRQVSRASKLIVEASPITTIAATRPVSLLGDVVVASIIERHASFVKVANLEWTSYCGPQMARVIFSKCHHLRYIHLGPRSHILFEGTKLPLDIIHEWLSANRHALRAFSYPSLSRSTPVQLPVLGSLASSSSTNLESLEVPILPWDNGALEPMPLVNTIEDIAQIIQSSPQLRRLVLADNKSNNNIGVIAEAIHNCYSLQVLELRHCLLTCDTFDTMLGTSQNSDFPDRTPLRKWKKLSLSCGPSSVIDDACLRHLIGRVPELQFLKLDQTQVKTSTLNSLLATTPHLRFLSISPPSPSAGQAGAILQDDKLKLPPRLIHLSLHGSKYHSPQMMSHILQQSTMLENIDLSCSNTVNDNDIANLVSFAAQQPHLMAQPEIASHMRPSFITISVTDCPRVTWQSVVKCIDHNQDVFRQRLECLGHAKHNHHLCNHPPLIRLLGHNEWRVKFESHFAFCLTQNCDYKRLEEMAADFKGSLVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCC9</accession>
    <name>A0ABR3ZCC9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Ferrioxamine B transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SIT1_1</name>
        <name evidence="11" type="ORF">Cpir12675_001968</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000034">
        <property type="protein sequence ID" value="KAL1898343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF92">
        <property type="entry name" value="GLUTATHIONE EXCHANGER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="186"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="215"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="262"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="299"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="340"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="376"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="406"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="548"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="46"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="583"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="587"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="601"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1898343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="615" mass="67076" checksum="A51376A56AD8AD7E" modified="2025-10-08" version="1">MPLFGSKGARPTGSDAAAKGPPTDSDSDNYINPEYNSKIVGKSSGVARIEALSSVLTHFDRIVLYLCIFLVAYVYGLDGTLRYTYQTYATSSFGEHSLLATINVARAVIAAAAQPTAGKIADVFGRMELVCVSVFFYTIGTIVQSTANNIEAFAAGAILYQIGYTMVILLVEIIIGDISSTRSRVFLSYIPATPFIINTWVSGDISSSVLKTTTWKWGIGMFAIIYPVCALPLIATLWTIDRRAKKQGLKPHGTHKRSMSELAVYLFWRLDVVGIFLMIAVFALILVPLTLAGGSSSKWGTAHIIAPLVVGIICVPVFILWEMRAPHPLVPFVLMKDRSVWSPMALALLLNFSWYMQGDYLYTTLIVAFDFSIKAATRVTSLYSFCSVLMGVFVGLIIFKVRRIKPFVIAGACLFMVAFGLLIHYRGQPNSSGRSGVIGAEILLGIAGGLYPYPTQCSLQATLKHEHLAVMTGLYLATYNIGSALGNTVSGALWTQVLPNTLEKNLAGINDTLAALTYQDPFTQAALYPVGTPERDAIIQAYRHVQRLLTVTGICLCVPIIAFALCLRNPKLNNKQTLAKDTHTTNHEGVNTNTASPEVMYNKEKQINEESEVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCH5</accession>
    <name>A0ABR3ZCH5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002186</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000040">
        <property type="protein sequence ID" value="KAL1897761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="63"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="471"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="570"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="679"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="331"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="109"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="505"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="571"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="686"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="698"/>
            <end position="707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="763" mass="82347" checksum="0DA72EF5D4B57A0E" modified="2025-10-08" version="1">MAEAISPDDSLLPKAAKDKACNFCGQAFTSSSLGRHLDLYIREKNPKPPDGLHDVDAIREIRGNITRRQPRSVSHREVSTPLGTPRPGASFRDSVSAVDDSAQRLPDGSISATNSASAPAPASTPVSALPSSATSNTSELRTRTVSRQITHKMQMESRQRMADTLDTAKATDLALREMISILKSVKKPQSSTCSPFDFDPLEFDFPSLTLQCLRPPPTLFSSTQHPTSTSWSVQPPGQGEFNALITFFAEEFRKWRVKCSSTTTQLSHELSLVPPTNSLRDARDAAMLAEKSVDTLHRQITDHLKSSYSVWKDLSRERQQEVWVLELARSIGRKNKENDALRDQNLRLSQEITALRMQTELAAATPKESPFGAPGTAMSDSDPLSSYLPELNNRGNRAGISSHINLEDDVTSILAKSVDRWRSVVTATKASATAMSAQRALDGSQIPMTPIATATATTTTLATATPSLTVPVVKTPQNRRISKPPSRAVSRGMQRQQQAKHQHALQHAQQQQEQQQAQKQAQKAQQQQQAQAQAQAQAQAQKQAQQQAQQQQQQASDGLTVEKMETSLVSEDADADADADADADADADADADADADADVDVDVDVTSGADVSLNVSGLNVDGDNDGDCEIDADADGDADADDDTEMQGNYMEMPIKLLTKTPIMPSQQHGGTLEIPRTRAHQPRLNNSNTNNATGSAVSGNANTANGASLAQGDARFMMAHGVRQPALNMRAMQNIGLGLSTQNAMVTANTVAMSIPEDIFMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCK3</accession>
    <name>A0ABR3ZCK3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RNA 3'-terminal phosphate cyclase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_002098</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000037">
        <property type="protein sequence ID" value="KAL1898079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.20">
        <property type="entry name" value="RNA 3'-terminal phosphate cyclase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.20">
        <property type="entry name" value="RNA 3'-terminal phosphate cyclase, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013791">
        <property type="entry name" value="RNA3'-term_phos_cycl_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023797">
        <property type="entry name" value="RNA3'_phos_cyclase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037136">
        <property type="entry name" value="RNA3'_phos_cyclase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000228">
        <property type="entry name" value="RNA3'_term_phos_cyc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016443">
        <property type="entry name" value="RNA3'_term_phos_cyc_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036553">
        <property type="entry name" value="RPTC_insert"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03400">
        <property type="entry name" value="18S_RNA_Rcl1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11096">
        <property type="entry name" value="RNA 3' TERMINAL PHOSPHATE CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11096:SF1">
        <property type="entry name" value="RNA 3'-TERMINAL PHOSPHATE CYCLASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01137">
        <property type="entry name" value="RTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05189">
        <property type="entry name" value="RTC_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="EPT/RTPC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="RNA 3'-terminal phosphate cyclase" evidence="5">
        <location>
            <begin position="11"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="RNA 3'-terminal phosphate cyclase insert" evidence="6">
        <location>
            <begin position="209"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="400" mass="42289" checksum="EDC9BA10351C3F51" modified="2025-10-08" version="1">MASTPEAIYFTGQIAFAQRLVLSTLTGRPVVISQIRNSSPTHPGLAPHEVSFLRLLDTVTNGSSMQISLTGTRTTFHPGLITGAIDGVGAVDGDIVEHIIEANNNRGVTYFLLPICLLAPFSKGHMNIRFTGPGVITSATETGDISVDTFRTSILPLFGLFGIPPARIELRIITRSCAGKNGRGGGGVVELRFASQVCLPKTLHLNRSDGRIRRIRGVAYCTGVSASSNNRMIQAAREILNPLVPDINIAAQYDTAPLVADKNGGKRRTGIGFGLSLVAESSSIGVIYSADVPAPPHGGVIPEDIGKQCAYQLLESISTGGCISKEAVPTVLTLMAMGSEDMGRVRLSKGAITPEFVRLARDLKQFGGSAWGIRPVDDESDDLIVSVKGFGVGNVARKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD59</accession>
    <name>A0ABR3ZD59_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transport and Golgi organization protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002248</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000041">
        <property type="protein sequence ID" value="KAL1897748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008551">
        <property type="entry name" value="TANGO2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17985">
        <property type="entry name" value="SER/THR-RICH PROTEIN T10 IN DGCR REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17985:SF8">
        <property type="entry name" value="TRANSPORT AND GOLGI ORGANIZATION PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05742">
        <property type="entry name" value="TANGO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1897748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="340" mass="38045" checksum="9B9D0CB27489FBCC" modified="2025-10-08" version="1">MCIALITTSHPDYAIVIADNRDEFFLRPTSRPEWWKHAAGHEILSSRDLHRAEKGTWLGISREGSLAVLTNYRETGPDDKEHPICAKRSRGGMVTAWLGSRSRESMTDAVHNLLAEGVSGVGGFSMVCGKLRKTGERQLQPLGIVSNRCDHIDHVEWIGDKRDQVYGLSNTVYGDPDSWRKIDDGMKMIDQAAKDAYARKLTEDQFCDALFGILDTNTFPDMSGASMEETIAYMRESIFIPPVGDKKHREVMEARRALGKGKWTNESETNVVEASPSPQRGGLVVGFDTGMYGTQRQTLILVDWEGNVTFKERALWDANGNPLVRGEADVVHKFKIEGWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDD6</accession>
    <name>A0ABR3ZDD6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl phosphatidyl inositol protein transamidase complex subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">GAA1</name>
        <name evidence="3" type="ORF">Cpir12675_001857</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000031">
        <property type="protein sequence ID" value="KAL1898653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007246">
        <property type="entry name" value="Gaa1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13304">
        <property type="entry name" value="GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR ATTACHMENT 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13304:SF0">
        <property type="entry name" value="GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR ATTACHMENT 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04114">
        <property type="entry name" value="Gaa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036762">
        <property type="entry name" value="GAA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="361"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="440"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="419"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="481" mass="53250" checksum="DCDC2293C9D6EB1E" modified="2025-10-08" version="1">MSRLISSAFQIRNDPRLLKAPPYLSLGCIVFGVAWLLLLPLDDYSRRTYISENALLPGQVHTYFSGSDQHVFRAYKSEVLALSNEDNYVVNDRLESIAHDIGLKSARQNFSYSSAGETYAGENLYAILQAPRGDATEAIVLIASWRNKDGELNKHGVPLALTLARYFKRWSLWSKDIILLFTPEPTMGSQAWADAYHDAHDTANAGSLPIKSGLLQGAIAIDYPQEERFESVHIVYDGTNGQLPNLDLINSIVSISNGQLGFQSNIQQMWDHSDSYDERLKTMFRGMVNQGLGHATGPHSAFIPYHVDAVTLRPYGTGWQDEMAMGRLIEGSFRSLNNLLEHLHQSFFFYLLMNRGRFVSIGTYLPSAMILAANFTIMAIAGWVQSGQARNANGSPAATLEKESQNVKEVTDSQKANEVSTPLTSTLPSSSVPSSIEREVSLPLAVVISIQSLGFVPLYLFNNTPVNVSANQVRYIDSICM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDW3</accession>
    <name>A0ABR3ZDW3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ipa protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_001907</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000033">
        <property type="protein sequence ID" value="KAL1898362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40788">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40788:SF1">
        <property type="entry name" value="IPA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1898362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="728" mass="81897" checksum="BBDEDAD8B37DCA1E" modified="2025-10-08" version="1">MNVHTTVIQLKKDLDLKWQLHGDTCQSVWATLNKKQREKCMRAGSMEGAVLKSPRDDSLGNVNKFLPEWNLEDVTKPSSNYLINLIEHRATRSLTQQYAEGVDGGLGDYHFILDMVVSRRLHCADNERMKDCWTLFIEGPEYGTSYRIADERAKSGFGPAIKASVCIPQEVGELILYRQMYLLQVMNIIIEDILEINSVDEPIPEAAKAKNKKSGKASGDQSTQSLAIRSVPAVKRTLQDLIPLVQDQADGVQEFLTLLTTSASLLDNEVNHRFFSQPGLIPDEKGRRLCMHTDNYISPIFLETVHQAVKGASLWNYLSQLMQLLAKHSNDKIYKPIILQEISNVCHFEFSRAQDTFKRHFQCHMGAKHFKRVSTSADPLGNHNVNIKGKPGALMSSDAQLCYMLRLCQPQTTASSAVQLVLALEILHRDDQEWERLSETEARSLGDLAAIVGLIQDISPTISMPPLSRKKGQMFVARSKSLDSEINSIKDQIDLSRFVIPIDNISKAEMAEGALQALDEFVNEKAGSNLGFLYQDLIEECLADLQRQYEAVQARVKLASSTAFSEWVPLPVPPQDEPAVRFEKRLEKQKTRPKHSSIFNTVPLSLPSLSLLTMKRDAKPDACKRISVNREALKVFGNLFRKSNARGSIDWVQFEKAMTAVGFRVTPKFGSVIQFSPPPPSAGNVSVQKSITFHRPHQSKIEGYRILYHARRLNSVYGWDEDTFLSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZET8</accession>
    <name>A0ABR3ZET8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Long-chain base-1-phosphate phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">LCB3</name>
        <name evidence="10" type="ORF">Cpir12675_001814</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the type 2 lipid phosphate phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000030">
        <property type="protein sequence ID" value="KAL1898707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03388">
        <property type="entry name" value="PAP2_SPPase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14969:SF28">
        <property type="entry name" value="DIHYDROSPHINGOSINE 1-PHOSPHATE PHOSPHATASE LCB3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14969">
        <property type="entry name" value="SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="70"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="265"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="9">
        <location>
            <begin position="100"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1898707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="540" mass="60080" checksum="74359BFCB1BC6EFC" modified="2025-10-08" version="1">MTGPEAAQTFVPPSKPEVIDAGLRSQNHYRKALPRWRYELRQKLIPLVRWETPHLSAFQQWARSPFFDSYFAITANLGTHTCFMIGLPVLFWCGFEAFGKGLVHMLAGGVFFSGFIKDLLSLPRPLSPPLQRITMSGSAALEYGFPSTHSTNALSVAVYSILTLWSPENTFSDSTKLTLELLCYLYAASIVIGRLYCGMHGFLDVICGSLLGVALGWLEFSYGAWLDQYMYQSSWIAPVLFSLIIIVLVRVHPEPADDCPCFDDSVSFAGVVIGLEFGTWCYGRAGFDMRAPIHQADYVAEIMALGWPVVVARLVFGVAVILVWREVTKPTMLHVLPHVFRFIEKMGLILPRRFFTSASQYKYVPDGAQLDTVFPRVSDIQDVVHTIRHPGRGRSVSVGPQSAADAYETIAYRERRRRESVDMDSTSSPNMRLENAAPANTDRGIVVVSSGSEVPGPVNVEAVQNERVGGSENDISDREVFSRLAKSRVRYDVEVVTKLVVYTGIGWLSSWTIPLLFEAIGLGLYPSPVLQMVMRQALDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF42</accession>
    <name>A0ABR3ZF42_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">hydroxyacylglutathione hydrolase</fullName>
            <ecNumber evidence="5">3.1.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glyoxalase II</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">GLO2_1</name>
        <name evidence="11" type="ORF">Cpir12675_001514</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an S-(2-hydroxyacyl)glutathione + H2O = a 2-hydroxy carboxylate + glutathione + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21864"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58896"/>
            <dbReference type="ChEBI" id="CHEBI:71261"/>
            <dbReference type="EC" id="3.1.2.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.6" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000024">
        <property type="protein sequence ID" value="KAL1899320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004416">
        <property type="term" value="F:hydroxyacylglutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07723">
        <property type="entry name" value="hydroxyacylglutathione_hydrolase_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035680">
        <property type="entry name" value="Clx_II_MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032282">
        <property type="entry name" value="HAGH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11935">
        <property type="entry name" value="BETA LACTAMASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11935:SF94">
        <property type="entry name" value="TENZING NORGAY, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16123">
        <property type="entry name" value="HAGH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="10">
        <location>
            <begin position="11"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1899320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="260" mass="29064" checksum="B5C867576B59EB39" modified="2025-10-08" version="1">MHIQAIPMFADNYAYLLVDEDSRDAAIIDPSQPSTVAPILQSKIDANDINLTVIINTHHHNDHAGGNDELRAILGRPNLRIFGGVQCQAVDHTPENNETIFLGTNVQLTALHTPCHTQDSICWYVRDLTPGKAEQRAVFTGDTLFIGGCGRFFEGSAAEMHHALNEVLAALPNDTRIYTGHEYTKINARFAQSIVKTPEIDALADFTEKNKVTQGCYTMEEEKKHNVFMMVNHGQVMSTLGETEPVEVMKRLRSMKDKFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFR0</accession>
    <name>A0ABR3ZFR0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Anaphase-promoting complex subunit 4-like WD40 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_001837</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000031">
        <property type="protein sequence ID" value="KAL1898633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4-like_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032847">
        <property type="entry name" value="PRPF17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43979">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43979:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="278"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="366"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 4-like WD40" evidence="5">
        <location>
            <begin position="447"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="498"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1898633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="531" mass="59632" checksum="7E32F5D68C4709D8" modified="2025-10-08" version="1">MADLNKFPANMVPRDALIVREQAPLSHTADIYSREEVSRPSVGPANPFSQDGAKKRKNNVLTGLAEETIVSEHTFRAKHQAVERRGGPERAIKSATEIKKEASNLRATREKKGDATIVEGAGAYVGPWAKYKPRYQDVVDDEPLASDEEYEEIEVTDDEDIVASGTTVSAPSVALERRKEVESLGTETTIFHGSQELDYQGRTFMHIPQDLNVDLRKEPGSITNFIPKKQIHAWKESKQAITSLRLFPKSSHLLLSASADSTIRIYDVYHSRELLRTYNGHSKALSDTHFNHDGTKFISSSWDRTIKLWDTETGKCIGKFTNGKTAHVVRWNNLSPDHHNEFIAGMSNNTILQYDTRVGNEIIQDYNHHLSDITTLEFLDEGRRFMSSSNDKTVRAWDYGIPVPTKIIAEIDMFAYTRSCLHPSGKHVLYQSGDNSILAYSTGDKIRQNRKKLWKGHHTVGTAIDVTVSPDGQFVTSGDSAGFLVFWDFKKGTMLHKIQASKTALTCMAWSEQETSKVFTAGQDGQVRLWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG82</accession>
    <name>A0ABR3ZG82_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Imitation switch two complex protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_001224</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000018">
        <property type="protein sequence ID" value="KAL1899725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018501">
        <property type="entry name" value="DDT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028942">
        <property type="entry name" value="WHIM1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028941">
        <property type="entry name" value="WHIM2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013136">
        <property type="entry name" value="WSTF_Acf1_Cbp146"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32075">
        <property type="entry name" value="ISWI CHROMATIN-REMODELING COMPLEX SUBUNIT YPL216W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32075:SF6">
        <property type="entry name" value="ISWI CHROMATIN-REMODELING COMPLEX SUBUNIT YPL216W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02791">
        <property type="entry name" value="DDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10537">
        <property type="entry name" value="WAC_Acf1_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15612">
        <property type="entry name" value="WHIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15613">
        <property type="entry name" value="WSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50827">
        <property type="entry name" value="DDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51136">
        <property type="entry name" value="WAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WAC" evidence="8">
        <location>
            <begin position="18"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="DDT" evidence="7">
        <location>
            <begin position="381"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="452"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="640"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="899"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="722"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="454"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="640"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="663"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="694"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="901"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="924"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="948"/>
            <end position="958"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1899725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1041" mass="119142" checksum="1938D54862BB7D6B" modified="2025-10-08" version="1">MVLYKRKPVVIPPPSADIRDDNAEVGMACPADWRDLCYLRRLLKSRKFICQITGQSKLTFFEALKSEKAGAKEVQQAFPESLKGPVLRRVQFQTISRIDHLVDNIYDEFKCEFFPGETVTAQITNTEKVQGTIREKIRVGPKLQSDGTMSQPFSRYVINIEDRENQEAVVDGPAVMRDRKIFTKAVLRTFIKNAVSREAWNGAPWVVKHEFADSYHIDTRIPQHLRYDHKVMQRKQLQAAKRTNHPMESNGFEDIHGLNPRHNMHHEPARLPDLKPKSHKMRPQLIANPMTFQSPASYEPTYVTIPPPSANYLSISLRNNNPPPLRKAQSPPPPVLPKYPIDDLDVGLRAGVVRPKLRFVCGDHPSAAPDDSYPYWSQLKMSSIGYLLETWDTLNVYCEIFKLDSFTFDDYVEALCITSLDTKPQLIEEIHCSVLKILVGSKADGGRVEFALPAEEEEDEEEDEEDSTMQISEPEEKPLGRATRSSMAKIEADRIAAEAAAAEKEAKQPELTNRASELLQDFDWIESLQKRQFQGGGWQRIIVGLLNQLSRNERKTKACEEILAELVPDAVEPTQETVVEQYATLDVNTKIRILQILCMLTTETKAVRGYMEDCSETMTQYRKEKIDWQRQRKQAIEDLKGLNEQRKVMLPDNMPPSPATDMDDSKMTDVDNSHVDEAENESDDDRSPVPNSRKAAKRDDKKKKLKKEETPATKTHKQSKQFIKLLKDIQKKEDAIKECEKEIAVIDNDLREADCPRTRVLGKDRFWNRYYWFERNGMPYGGLPDSSTASAAYANGCIWVQGPDDMEREGFIDLPTDLQNEYKARFNMTVTERKAREESDTSVFNANQWGYICEPDDLDKLIHYLDPRGINELKLRKELVTFRERIITNMKNRKIYLGIPDEPKDKEDADDGVKEDKDHKVENADTTTGPPSPAVSNATNNDDDGSKRNGKRSMRLKRQSQPQPPAPEDDVMTNKSEDTPMPQPLRCLKWENTVAIEEFGHLHSEPPPPPPPPPKRRANNKKRESTAVTEVDEPPRKTRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG86</accession>
    <name>A0ABR3ZG86_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histone-lysine N-methyltransferase, H3 lysine-4 specific</fullName>
            <ecNumber evidence="3">2.1.1.354</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">SET domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="primary">SET1</name>
        <name evidence="22" type="ORF">Cpir12675_001441</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3. Binds RNAs which might negatively affect its histone methyltransferase activity. COMPASS recognizes ubiquitinated H2B on one face of the nucleosome which stimulates the methylation of H3 on the opposing face.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:60260"/>
            <dbReference type="Rhea" id="RHEA-COMP:15537"/>
            <dbReference type="Rhea" id="RHEA-COMP:15547"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="2.1.1.354"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:60272"/>
            <dbReference type="Rhea" id="RHEA-COMP:15537"/>
            <dbReference type="Rhea" id="RHEA-COMP:15540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="ChEBI" id="CHEBI:61976"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:60268"/>
            <dbReference type="Rhea" id="RHEA-COMP:15540"/>
            <dbReference type="Rhea" id="RHEA-COMP:15543"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61929"/>
            <dbReference type="ChEBI" id="CHEBI:61976"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">Component of the Set1C/COMPASS complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.354" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000022">
        <property type="protein sequence ID" value="KAL1899405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140999">
        <property type="term" value="F:histone H3K4 trimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20072">
        <property type="entry name" value="SET_SET1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024657">
        <property type="entry name" value="COMPASS_Set1_N-SET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044570">
        <property type="entry name" value="Set1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017111">
        <property type="entry name" value="Set1_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024636">
        <property type="entry name" value="SET_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45814">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SETD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45814:SF2">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SETD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11764">
        <property type="entry name" value="N-SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11767">
        <property type="entry name" value="SET_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01291">
        <property type="entry name" value="N-SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00508">
        <property type="entry name" value="PostSET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51572">
        <property type="entry name" value="SAM_MT43_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6 22" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="17" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7 22" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RRM" evidence="19">
        <location>
            <begin position="285"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="20">
        <location>
            <begin position="1101"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="21">
        <location>
            <begin position="1227"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="16"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="118"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="403"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="546"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="650"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="807"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1025"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="118"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="169"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="403"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="560"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="739"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="821"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="18">
        <location>
            <begin position="847"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="863"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="885"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="1026"/>
            <end position="1041"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAL1899405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1243" mass="138453" checksum="DE1A82D99F77361F" modified="2025-10-08" version="1">MSRSLAASFAQFFPAASREAKDRASERERLSRKHPISEANLADGVDATTAILESPSTSFSPPAQLNSEPCPNLLDTQDSLSLNRESLNPGSDSSHSSSIEISMAANGAFQSSAAVTITPLSSSDSPQPNVQTLDTKDQHPVSFSSNLNSQSLITMTPSSEPHNIYNNSNNKTTTTLPLSPSPAQTEHIPARDTSRSILGLRCIYDPFSDRSASAKSAKRDLEPRFKEFGPNDDIPPADPRLAKGGRLGYINVDFHLPKSRLRHAPYNLKPYQFDARTSIGPSPPTQIVVSGFNPLMSFAKLTALFSQFGDIAESSNKLDPEDGSYLGFATFRYRDSSPNAIRRIFVAAIDAARRAVRDANGRRIDTYRIKVEFDADGKRSIQMMRAVERESQAKVAQILAESTQLAKSKRGSQTPVSRSGHGPPPTAPKGPANKPAESRPPAPRTNPPVEAQTLATTLKELPYIFISHSAVPVMQTTIPHLKRRLKSFTFDDIQLDRTGYFIIFESSNYGRIEAERCHRQCNEAELFTYHMTMELFVPANLVNHIGSSSTRHRRPSTPELKARAEQRQKEEQEQLKRELEEDIEEEKRQRAKNFDPVGEAVQVIRRELLEHLIRHIRVKVAAPAVLDFMEPANHVAKRRELNLEIPEMHSSFLDDSEGPSRAGTPNSRADPIENRTGKFDVSALPRIRKFKSAAPPASSLKANRKAPNRQNAIRSLHHRLYDSESDSDDDLQAPKQRSVTRDTEEYESRPRSRMSTDEDKEERATWGGAEEDSMTERSFAATDGSQVRKRKLELLEEVVIKRQKKLDEDAMETDSVAPTDDGNHDIDTDVQSRAETPVLQPATGKAAPKKKAAPKSKKKTKKQLAEEAEAAKRQAEAAAAVIAEPKAEPEPSAKPVAREVKEKVVKNLDPKLFPSSPMPALELSVNTIISDFRILNGLGLGAHDAPDVSQLLCRSKATNMEQPELWLWTRDRLRTLNANKSSQDGSAMIEGYYLPNPTGCARTEGYKKILNSEKSKYLPHHIKVQKAREERQARVSKDGKDPTASAAEAAKLAAEKLISQGNSRANRANNRRYVADLNDQKKTLGQDSDVFKFNQLKKRKKPVKFARSAIHNWGLYAMEKIPKDDMIIEYVGEEVRQQISEIREKRYLKSGIGSSYLFRIDEDTVIDATKKGGIARFINHSCMPNCTAKIIKVEGSKRIVIYALRDIALNEELTYDYKFEREIGALDRIPCLCGTAACKGFLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGV5</accession>
    <name>A0ABR3ZGV5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CAP-Gly domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_001322</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000020">
        <property type="protein sequence ID" value="KAL1899645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032108">
        <property type="entry name" value="CLIP1_ZNF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16641">
        <property type="entry name" value="CLIP1_ZNF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CAP-Gly" evidence="8">
        <location>
            <begin position="185"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="63"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="235"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="568"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="653"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="691"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="868"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="425"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="238"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="313"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="359"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="389"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="568"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="613"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="691"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="786"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="885"/>
            <end position="906"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1899645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="947" mass="101625" checksum="18C8E85B61AFECC1" modified="2025-10-08" version="1">MIVSSPLAVQPSSDSLPSLSIPRVLPRSLRKSASAIGLNSGSLNNADVSSAASSLHGLYIRPGSSQGIAPNKNNKNNKNTYGTHRHTTDNSSSEQLQPPPLTLGRKKSIPGLNPSALASIPDSNESYASTSIFGESSSRTPLTLDTTSHHHKSASKINANMADDLLVGDIVDVPGGMKGTVRFVGSVNSKKGVFAGVELLPEFAGRGKNSGDVDGISYFTTTLAGAGIFVPATKVSRQDSSNSYPATPTISGIKGYSQNANSTTPPTPSILKFSQSVGPGRTASPLGKKPRPSLHRPESPLRRVQMTPVPRPSINSSIKSPTKGSKYGSPTISKFSQSVRGTAGDPLKKLPGSRLDLKSSLIGSRSSSAMGMRPMSFDDEEPPVPSIQRARTNAGVSSASRNRPSSRTATASSNGHATQASDEEIERLRAQVEDRDRQLRDQAATLAEMESALAEVQQLMEHPNNMRQNRDNADDHDTAQLRTLLREKNEKIALLTSEFDSHRADFRSTIDALEMASTETVRVYEAQKKDLVQEINELEARLEDVDAVARQLKQLEELVQELEEGLEDARRGEAEARGEVEFLRGEVERTRSELRREKEKNGGSAGNGSGGPTAVATTNSASTSTNQSSLTTSKHLEQKEDEIRGLKAIIHSLSRDSAPNSPPITGPSNGSGDSVETRLLRENQERQINELRAMLDSKTDREEELEREIEGLRRSGSFTTKPLNSSRPNSHTHPTSHPHRASGMTIRPSSLRDSAKNGISHIHERSSGPEPRTTSSDMTGHKRGSTLDTMPESDTYSTATETSTLWCEICETNGHDILTCTNMFGPDGPKPTSAAINGSNRDTLKAMAINTGIGDQQTQDEIYKVAPLRSKNSPPLPSDEFTTTPSAAQPPALAPLAAAEPAKVLPNPMESGPVAGKESGTIDPSKWCAVCERDGHDSVDCPFEDAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGZ4</accession>
    <name>A0ABR3ZGZ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001342</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000020">
        <property type="protein sequence ID" value="KAL1899664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011666">
        <property type="entry name" value="DUF1604"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13384">
        <property type="entry name" value="G PATCH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13384:SF19">
        <property type="entry name" value="G PATCH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07713">
        <property type="entry name" value="DUF1604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26093">
        <property type="entry name" value="HTH_TGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="2">
        <location>
            <begin position="108"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="550"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="572"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="619" mass="66956" checksum="B871F6386DDF3883" modified="2025-10-08" version="1">MTKGGEDFMAHSPEGGVLGMYFNTVGSKEGWTPSAFLSSRTSRAEAANIQAQNPTQKPEDFMDEEDMENVLASTHLQIADGPGAELIYGGGSLVSSPLDLLLMGQTSRETTGYRLLRKMDWKPGQGIGPKIRRSARLYIDGDAGYSEPTSAKEYMFAPEDVEVIVADHKQTRLGLGYDNNALGTQEGLINRNVQDEDDRPHRFQNRIPLVRSASSSKFIEKTAPLVGVSLHGDDDGDEDDDLRPRINYNKTRPVKSTKKGKKKPNSVALAKPNAKRDPITLGQDQGLSSSKAPTGFVSSSRTLVVVATSSPSQNLDPPAVPSGWVSVFSTTDSTKPIYSATSSIITNTPVHRAAALGEKQLPSQSIFDFVTPEARARLAMVTGKSDLPAAGGKPVPSVAISVEDAYTTSPSLDRESALAALIRANTAGGPYHNNESKLQRYILYLKFQAKQIDVPDISWGLSPAELRLELAEFYNCARIFKPMTGFMASRFAPSSGSQSQSLPDVVPVPKHEDSAAEAAKLGLYGALTRSVQEFVPVQLLFKRFNIPAQSSHTVTSPKPTYGSESGVLGDASLSTNKDSSNDTKSQTPQQQQQQQPEASKTLSRPPDDVFLSIFEDQDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH18</accession>
    <name>A0ABR3ZH18_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_001288</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000019">
        <property type="protein sequence ID" value="KAL1899705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12398">
        <property type="entry name" value="RRM_CSTF2_RNA15_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.70">
        <property type="entry name" value="Transcription termination and cleavage factor, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025742">
        <property type="entry name" value="CSTF2_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026896">
        <property type="entry name" value="CSTF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038192">
        <property type="entry name" value="CSTF_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45735">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45735:SF2">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14327">
        <property type="entry name" value="CSTF2_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14304">
        <property type="entry name" value="CSTF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="8"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="83"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="228"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="281"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="105"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="281"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="297"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="352" mass="36843" checksum="F03DFA28E647E8AB" modified="2025-10-08" version="1">MSFKIPSRVVFVGNIPYDLSEEQIIEIFNSAGKVINFRLVYDRETGRPKGFGFAEYPDSDSASSAVRNLHNYEIKGRRLRVDFSNEGGTEDEDGESMSFGGMNAGLGPATTTSGGPGTTPTGSAGAPNTSSSLPPLPAGKELPPGVTCADQISRTLSTLPAPQLLDILSQVKLLATNEPNRAVELFEAAPQLAYSIFQALLLMNLVSPDNIYSVVDMNSLAAAAVAGPPAQQPGVAPSQVQLPSAGSVPPSMGSGYPNNGYGAPPVAAPSQMPIPMAPAAYNRQQQQQQQPYSAAVVPPPPPPAPSAPAGGQDSGALMRAVMDLPQETIDALPETERMQILALRASYQAQSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI98</accession>
    <name>A0ABR3ZI98_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Karyopherin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MSN5</name>
        <name evidence="6" type="ORF">Cpir12675_000963</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the exportin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000013">
        <property type="protein sequence ID" value="KAL1900381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045478">
        <property type="entry name" value="Exportin-5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045065">
        <property type="entry name" value="XPO1/5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223">
        <property type="entry name" value="EXPORTIN 1/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223:SF3">
        <property type="entry name" value="EXPORTIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19273">
        <property type="entry name" value="Exportin-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="5">
        <location>
            <begin position="38"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1010"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1228"/>
            <end position="1256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1012"/>
            <end position="1028"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1900381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1256" mass="141449" checksum="95FB0BF15954677B" modified="2025-10-08" version="1">MEGHSPNGASPEAVIPQVHEALRVVHDPYSANNTRQEAQAFLEQVKQSSDAPLVGYKLAIDSAQSPIVRHYALSLLSFTITQKWEDFNDQQRTTVREWVLQLCQAVSKDDPMYLRNKVPQLWTEMAKRDWSDRWPDMDASLLKLWQNSDLPVHKEVVLFVLESLSDEIFNSTDYMVMLRDSVLSKSCVEIFTSASVLAEAFPNRTTSSPSIRAGEEGWLVRVNSFLGQCLGADVQNNEDARSCAVKSLNVLASLMSWAVPLAVKNANIVPVVCQALAASHVSVQKAALNCLYVLYTRVTFSDEDLLGLVAPMFEPEIVSLCQRLSEWAKVDANDIDIDKYQFAKKFSEMLSHLANYLVSKLSIFPPTADIPGFLNLLLQVVQSESLVVSIPVLVSWTKLLTHRTIGPDAANNDQVLGILLQVCSSRQVRYEHFPEDSEDPSYLFLMEDTENLPERHAFLGNYRRFSAQVIEAIVRLKLSESFEYLLGQVDEVIQHLYDSEPRHSVTNYSKYSMPVLKIDTNFAVVEIALKSYAKRRASEGGIPPDTRAMLETYLEKWGRSLLAINFEDPQIRKRALQLLVALSTTALDSNSPFMLSVLEHILMYWPTLQPENKAYNEAIKDLQNESMVELQRLAAKVPDHLIQVYDQIASRVNELLNSGTLDDKRAVAYRSFLFLIIHRATKLPIDQRMSKLISFVQPTFEQWKSPQLLEAISTYQGFCQMLGLDKAQQYLASHRVNEVSEWGECKLDEEGLGIQAELEERQQMLPLRATKAFLAISVEKVTKPSVAFSYSIAIWKDNFQSILSALLQFLGHAHASHNPSNWHGLPENIRPAVVSKVLSDRFWQAGISEGSKDDFYNRVLDKKATLEGLGSTIRGSIRFVRETAYAVIYCLSRMDELFYTLPELPNPLAHALFSDSLFISSHQQISLLNLVRYLVDDCPVENRENFLPPVLEACFRQMDTKINSEWEALASQQTVQTGGDELTEEMKAESILRQVTYTAVVMVADFLDPNKKNPSPKSDPSSSSALLDNEPKYPTLRRFCLSRQGIVEPLLVFSTHAIRMKDSRCCGYILRVLRTIASDLRAQPIGSSEGRPNDHMAAFPIPHETVTAIREFMSTETLQACITSFHEPYFVDTQKDLSYLMAAIYVYFVPVTNTPVKILLSLPGITTDKLQAMNEFLANPDNTPRLQRAAMFDLLKHLKGVSIAEMGKLDAPAKKKETRSKMAQEFMQAPNQNGGPNIPRTASPDGLDGVSNLFEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIV1</accession>
    <name>A0ABR3ZIV1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001034</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000014">
        <property type="protein sequence ID" value="KAL1900350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="474"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="681"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="77"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="477"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="686"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="713"/>
            <end position="722"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="739" mass="79781" checksum="FD6AD651C632CD86" modified="2025-10-08" version="1">MSTTVANNQSRNSAQISVLSSLWDEPMDTEMDVSFCSDSSNSSASFIDSHKINTLNTTDGTYEEPTLSKAGPTSIKSTSTLSPANNTSTSATTTTASITTPPSSLQVKKRTEDVVSKAASVRVAPSVSLNDQTFNSPTTSIENLRRAALGVRTRITSLENEVMRSKSPLDKLKDQSRRGQVRKLSQEYEAARSQWVRRAATDVRPKADSKPPGLRPLDTTLNVCSIKDELPKLEPVKAATFPCSFATANEAAQKSNQLSLATSVPAFSDASRGDAVVSPVASSCYSVTVPETQSTLLEARRQVSLMSNISQYNMGAALYGSSSRPTSRDVYSKASASGHMNAATESIDNSQWTSQLAAKSHREGGRISRSSSHYTDGDDLHNSMTRDSDYHNSGRYSAQWTELTELTMPPTELDKNDDFNRLSLTFPENMDMAHSNTSNQVDFKTYSAADPAEAPPASPKKSIFRAMFNRSKATDLASTTHSHSRQRSSTTTATATAQSNQGGYEPIGDAYGQPRHSTSMATITPAAHNGQNAYAGTVAASGDVNDENVAFSDCGAISNVSNMLGPRRLQVTSLEGQASELAHHNMEPTNASSEQSVYGYMTPSQKAFHLFKKVSQPRKWKESREKKRFNAEKTLAAQMNLASGYTLATTPTASNLMAPSIATSLVPTTVTIIESTNKPIEEEKKSRKTLSKLHSKASKLFGKDLKKRPNKPATESTDTDFSNGLPAIPVSEIDELASC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ44</accession>
    <name>A0ABR3ZJ44_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">mRNA decay protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">NMD2</name>
        <name evidence="5" type="ORF">Cpir12675_001075</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000015">
        <property type="protein sequence ID" value="KAL1900075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.80.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039762">
        <property type="entry name" value="Nmd2/UPF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007193">
        <property type="entry name" value="Upf2/Nmd2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12839">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY PROTEIN 2 UP-FRAMESHIFT SUPPRESSOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12839:SF7">
        <property type="entry name" value="REGULATOR OF NONSENSE TRANSCRIPTS 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02854">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04050">
        <property type="entry name" value="Upf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00543">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIF4G" evidence="4">
        <location>
            <begin position="508"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="domain" description="MIF4G" evidence="4">
        <location>
            <begin position="712"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="247"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="943"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="959"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1007"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1030"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1061"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1106"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1157"/>
            <end position="1175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1900075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1191" mass="134048" checksum="FEE30A834EF7D7BB" modified="2025-10-08" version="1">MDREKRQTLRLLNTRAWDGEQDVFPTSASLDSSLKKNTAFIKRLRTTISAATLPTFLQEIRTLSLHKYLAEIVSACYEGLCKLKNPGDVESCVEITSALHQRFGPTEFTMYLGWLLGKGMASPDKSLMKTLSPEQREKSEKERIPRQRILLRVVTELWLVDVLRTLDDVARPDDVALAPKAAATTKTSEAKAKAVRQGVSADPFPYGVLKDLLNHDREHANLPLLVIFVKSFNWDILGVKPLTAEGRRTTDDETTAITNTNGNPQEDGGDSPGKDAGAESSHTKDVSDSESHPPFASAELQNKFKHILSMYFEDVKRHVIRGQEAITEQARKNSETYVKAGEVFEDRQASFDKQLKVQERLVASAQVLADAVGAEMPDLRNFPDSGVNANGSIGLVKAGEYLRSLGEGAGIWNDEDERRFYENLVDLKGKVPPILLEDAKKKKQDNDEQVGKPAEVEAAVAVAPDTSSAGASAAASVIAPTPTPMPTATPIDDQSMIIANKTIGAQVDALVGRLPSMNTKDLVDETAIDFCFLNSKASRNRLVKALTDVPKGRSDLLPYWARLVATLGQYMADVPKGLVDYLDAEFRSLQRRKEKEFLGQVRLANIRYLAELTKFGIVPEHVVFHCLKVSLDDFSRMNIDIMCNLLENCGRYLFLNPETSPRMTSLLETLQRKKSVLHIGPDERMKIENAVNLVNPPERPAIQQKERTPVELYIRKLIYSDMTRRNYSKILRQIRKLHWEEPEVVHILVKVFSKPHKIKFGSIHLLAIVLSALYRHHPHFVVDVISRLLESITQGLEQNEYRLYQKRVAEMRYLGELYNYRMLEHSIVFDTLWKVILFGYPGPPIPGTNPLDPPDDVFRIRLVATLLESCGTYFNKGSAGKKLDHFLTMFQYYIFTKGQLPMDTEFVVQDVFFLLRPQWQMAIDIQEAAVIFQSSLLEQQKAAGIDTSQDPDEHNQSDDASDDSGESDDGDDDDEDDSSDEEDDDDDDSSDMGMSSEDETFVVNQPEPEEDPEEDDEFDREYAKLMAESLESRKHDRKLVFDVPLPIRPRGETGIAGGTGRSNYRSSATSGNGSSTFANGDDDHIKSSTGPGSKMAFSLLTKKGNRQQTRTFELPSDSSFAAALRTQQQAEREEQQRIKNLVLSYEMQESDESDGQETARDRDRPATFQRLDRKDRNKPHSRKLQWSDVEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ97</accession>
    <name>A0ABR3ZJ97_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LYC1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000804</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055100">
        <property type="entry name" value="GNAT_LYC1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053013">
        <property type="entry name" value="LAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34815">
        <property type="entry name" value="LYSINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34815:SF2">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22998">
        <property type="entry name" value="GNAT_LYC1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LYC1 C-terminal" evidence="1">
        <location>
            <begin position="150"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="333" mass="36510" checksum="304B6ABF70A66CE2" modified="2025-10-08" version="1">MSSLLDSIAIVLASPAQRHAAWSLNSTHWRGPLTSQAFIGREAHLSQTALASGDGGLYFVAVPKDSVESKGGHADENVEPVVYAICTALRKRVLVRCQGCAVEEATAYGIGSRELDIRGAVLSILYSDIGRKFYADLGWAAMPARTAVMPISKPAAGEPEGVTWLSDEDLQRVTTQDTKQLHDSLVTDASSPTVRIAFLPDFAQLDCSLQRSQITAQALRTAVPQTTVVLRRRGAQTSSGTSWVWWDHRLHDGQLKILRLTVDSADATARETLLRAAHHEAAVWGLSEVGVWDPCGAEFSEVIDRDLGVPCLRWQNGEERDIEWVCNEYYAWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJC9</accession>
    <name>A0ABR3ZJC9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000694</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051181">
        <property type="entry name" value="CAF1_poly(A)_ribonucleases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006941">
        <property type="entry name" value="RNase_CAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15092">
        <property type="entry name" value="POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15092:SF22">
        <property type="entry name" value="POLY(A)-SPECIFIC RIBONUCLEASE PNLDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04857">
        <property type="entry name" value="CAF1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="419" mass="48142" checksum="A445E2D7BED410F2" modified="2025-10-08" version="1">MEVNTANFPELLPQILTHIKSSLFCSIDLEFSGIKASITTQKLGLTCVQVDGSDYKTQSYSFMVTPFLSFLDNASTRQARSRDLERRLVFSASSMEMLMNTGFNFHQALKNGVPYLSRQEQDILQSNDIIERNVQRKLGVKLPGQFTNIVIEQAEKPWYDKQKKHISEWIINGMAKTLLCYPEECYQITNRHRDMALSIIPENLTVTIIRDCKNNCLVIRHHKREDLDEALKKQAQAMRQDIQHCIGLRLIIEALAGNPNLGAYLDCHWYGHRHASYNVHACGGDTATMSEATSTLQDLCDEYSTLSQKKQEFPYLVGHNILWDLAFLHQCFVRELPKCYDEFLTSIRSMFPRILDTKVMASTIDSALTNYSLTSIWRRISNKVPEIKVEIPYDAFQCGVAHDAAYDSKTRIESFFFYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKK8</accession>
    <name>A0ABR3ZKK8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000776</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="273" mass="30092" checksum="467B1E7830703EE9" modified="2025-10-08" version="1">MSTATEVQVQGGIRTGDARGGSATGGAGGSATGGAVNAYNFAKIRDVSSYDYLHVDLAPSYGGLSKESIKLLDSNLKVMIAGTVRMIKKIPPSQRKWKTIEQAFTEKNHVESSGEPVHRKDMLLKKEVHAFKMSGAADVDIVKLWFHNLVNDSDVLAATPIPIEELAEIVAWSGATVTDIGTAIYKSEKHEKKIMDIGILRFPDSIHPYFKVYHITLKAWSYSSRMVTVQSDNNGIEGEFYSRIFKPRKEILAKMNPEVIQKAVPEAESMFDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKW6</accession>
    <name>A0ABR3ZKW6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Molybdopterin synthase catalytic subunit</fullName>
            <ecNumber evidence="4">2.8.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Common component for nitrate reductase and xanthine dehydrogenase protein H</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Molybdenum cofactor synthesis protein 2 large subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Molybdenum cofactor synthesis protein 2B</fullName>
            <shortName evidence="4">MOCS2B</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">cnxH</name>
        <name evidence="6" type="ORF">Cpir12675_000824</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2 [molybdopterin-synthase sulfur-carrier protein]-C-terminal-Gly-aminoethanethioate + cyclic pyranopterin phosphate + H2O = molybdopterin + 2 [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-Gly + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:26333"/>
            <dbReference type="Rhea" id="RHEA-COMP:12202"/>
            <dbReference type="Rhea" id="RHEA-COMP:19907"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58698"/>
            <dbReference type="ChEBI" id="CHEBI:59648"/>
            <dbReference type="ChEBI" id="CHEBI:90778"/>
            <dbReference type="ChEBI" id="CHEBI:232372"/>
            <dbReference type="EC" id="2.8.1.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MoaE family. MOCS2B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.12" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00756">
        <property type="entry name" value="MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.40">
        <property type="entry name" value="Molybdopterin biosynthesis MoaE subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03052">
        <property type="entry name" value="MOC2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036563">
        <property type="entry name" value="MoaE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028888">
        <property type="entry name" value="MOCS2B_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003448">
        <property type="entry name" value="Mopterin_biosynth_MoaE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23404">
        <property type="entry name" value="MOLYBDOPTERIN SYNTHASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02391">
        <property type="entry name" value="MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54690">
        <property type="entry name" value="Molybdopterin synthase subunit MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 4" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="124"/>
            <end position="125"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="147"/>
            <end position="149"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1900690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="173" mass="19349" checksum="4BAF8B2D2A4C8965" modified="2025-10-08" version="1">MSEESCYVGLTFDHLSVKDAMDHVRSPQAGAIVMFVGMFLFYTISINALWLTNGHPGTTRDNFDCKTVKELQYSAYNKMALRTMMSICREMVAKFGLNGISMIHRLGPVPIGEESIVIAVSSPHRKAAWEAGEEALEQCKAKVQVWKREEFDDGEGVWRANRDGAKGVKVEET</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLP6</accession>
    <name>A0ABR3ZLP6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46563">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46563:SF1">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="563" mass="64369" checksum="2E49F5FEA4CCC644" modified="2025-10-08" version="1">MPEASLSSLTKPLYNSWQPTSDDQTPPGGGLRIVVFGTPDVATAINGALGKQEKSWTEKLCEELRCTEHISYVPTTNNSHVQGIDAALTSNTLWQHAIDTATNANIDLGVPGYDYTFIKEQYPMPKHPDLLDQVTSFVSSPQPSTNPKETLWVFNFGTWDIWYLSALPRDLATHYIDSLVIRIFSQLDFLYQESLNERSIAFSDFWHYSSQELADKTRNSYADWEPQEIENFRVLLPQLFDISVSPGWNEARPTPPEPHSKAEQDRNALFLTNRWNEMIAQHISEWNAKEVPTSDQEYDHIIEQKSYADFAKATEAKAKEEKEKKAKEKNEKEKKEKEKKEKEKKEKEQKEKEQKEKAQKEKEQKDKEKEQKEKEQDEKQNKRSVLSARQTNSHTLKSLHAELTERSAEKLEKQAAAASSLRNRQNRVHKRWHHSIHGSSTDETIVAPFPRRAAAQFDGQVFISEAIIEQQFRVRNISDHLGRGVRPDTDLAVFDNVNKPCVIGETSPLNQKVCSNPDDYLFYTLFTVNQPAINVIANRASVIVYDTLLLPKPGTVDAAAEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM11</accession>
    <name>A0ABR3ZM11_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Class II myosin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">MYO1_1</name>
        <name evidence="13" type="ORF">Cpir12675_000550</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01377">
        <property type="entry name" value="MYSc_class_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.360">
        <property type="entry name" value="Myosin S1 fragment, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.270.10">
        <property type="entry name" value="Myosin, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055914">
        <property type="entry name" value="DUF7491"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008989">
        <property type="entry name" value="Myosin_S1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004009">
        <property type="entry name" value="SH3_Myosin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140:SF857">
        <property type="entry name" value="MYOSIN-11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24319">
        <property type="entry name" value="DUF7491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02736">
        <property type="entry name" value="Myosin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90257">
        <property type="entry name" value="Myosin rod fragments"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51844">
        <property type="entry name" value="SH3_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 8" id="KW-0505">Motor protein</keyword>
    <keyword evidence="5 8" id="KW-0518">Myosin</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myosin N-terminal SH3-like" evidence="12">
        <location>
            <begin position="199"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="Myosin motor" evidence="11">
        <location>
            <begin position="253"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="8">
        <location>
            <begin position="832"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1751"/>
            <end position="1796"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1834"/>
            <end position="1858"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1031"/>
            <end position="1356"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1403"/>
            <end position="1526"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1556"/>
            <end position="1611"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1694"/>
            <end position="1735"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="2045"/>
            <end position="2157"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="2207"/>
            <end position="2234"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="2279"/>
            <end position="2454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="36"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="91"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="346"/>
            <end position="353"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1901184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="2502" mass="283615" checksum="5760B814ED86D346" modified="2025-10-08" version="1">MSQPRRNNPFMRAGSPSATSPLSSSGGSGVTHRPKTSSISTPSPLSFPPTTAEATASGPASAGASTTPSSRATTPSGSNASTPTREEDEITTTATATTATTATPTAAQKTPPTVAASLSQTASPASIQKPKLQSRSMSFGASFGSPLVPANTARRHSRVESKNSSRLSNTFAPSFIQSEELQRADSDTVDKLEGENDFSGKRYVWLKDPAVAFVKGWVVEELEGNHILVQCEDGTQRQVASDQVDKVNPAKFDKANDMAELTHLNEASVVHNLNMRYQSDMIYTYSGLFLVTVNPYHPLPIYTNEYINMYRGRSREDTKPHIFAMADLAFRNLVDEGLNQSILVTGESGAGKTENTKKVIQYLAAVARSDSLNPAKVRLQHSNLSEKILRANPILEAFGNAQTVRNNNSSRFGKFIRIEFSRQGVITGAFIDWYLLEKSRVVRVNRQERNYHVFYQLLKGADRRMRQEFLLGDCDVQDFNYTRFGQDTINGVSDKDEWMGLLDAFNVMAFPEEDQVSILRTIAAVLHLGNIEVVKESRSADQARLATDAKDHVLKVCRLIGVPVEPFLQGLLHPKVKAGREWVEKVQTPDQVRLSLDALSKGIYERGFGDLVNRINVQLDRSGFSMGGMEDSNFIGVLDIAGFEIFESNSFEQLCINYTNEKLQQFFNHHMFVLEQEEYAREKIEWQFIDFGRDLQPTIDLIELPNPIGIFSCLDEDCVMPKATDKSFTEKLNSLWDKKGNKYKPSRLGQGFILTHYAAEVEYSTEGWLEKNKDPLNDNITRLLAASSDKHIAGLFADCAESPDDVNGISSQRSRVKKGLFRTVAQRHKEQLHSLMTQLHSTHPHFVRCILPNHKKRPKQFVNLLVLDQLRCNGVLEGIRIARTGFPNRLQFSEFRQRYEVLCRDMPKGYHDGQSVATLMLDKLGLDRSLFRVGITKVFFRAGVLAELEEKRDALITEIVSRFQAAARGYVQRRIAYKRLFRTEATRILQHNFRVYLDLANNPWWQLLLKMKPLLGATRTAAEVKKRDDMIKQLSDKMEAEAGNRQRLEEERRNTHTELTKIKHILESERALALDKEEIFKRLQNREAELEEKLSGALEDQDRLEDQLDAILIAKKQAESEVDKFRAQLEQAASLISRLEEEKTHLSLKIDDLEKSIDEINKKQSERSAQEEALSDEIKMLQSQLSLKERKVKDLETRMLKNSQDLEVQLHSTQKELQSAKSKEQRLVRESANMQKQLTQLSQTSTDYEDLVRKKESELSVLRNDKRNLEAEKQQFDEQRKTLVADRESTATRLRDVQAELVALKSQHTSLQKEAQDANKLLQERLSEDAQADKNRQLLEAQIKSLKDELYKTQVELSRERQSRDDVLLLGEHKYQQLKDEYGHLNDSKIIIEKELYVQQDILRRATEARATAEEERDAAREEIRKLRLAKADAEEARIHAEEAGERQAREMARAREESLRKDLDAAQERLTWFEAECNKLNHEVEDLNKLIIESGEFGLQNDQAKERLERELHTVKSRLTASENDNRSLLNKLQQKGLEIARSTTKATEANRSQIAMLTKEKKRTEEQNSILNKQLSEAQIGVTSYKKKIEKFQLSVEDLNHELAREAKATRAAEKALSNSTAQMAESKRTIDSERQLRTQAQSTVRTLQATLDSRDKELQDLRAQMLDVLRIVDPDCATSPIEVSSKDKDVANKARLENFDLLRKTEELQQNLRIQTAARNNAETQLAEIRAQQGVVAAGDLRSRLEDRTNGLNQSPTHVRHSSKTNLFTRDPFATPPRKGTANGAMDTADSARSDKTADILSFNNRQDLKADVEELQNQLQIALMQNRHLQSQLDRAPAGSGAGAGADSSDESPTRRRMLKLEAANNRLHSLLDDSAKKVSFLEKSVRSGELSLRDLQTRSHEEILQALNSQEESRRLLLHSHKDAVAELAEIKASFEKMRHDRSAFEVDARDARSDLQEMTLAREQEAASRSQLLQEFADLQIRLDAETSKLAEVTSSMTLYKGRADEYFSKLEQAEIAVLKASRAEQFARAQAKEAEDTCAEVMTERKKMDSTLEDLQRQNRRLEERLEDTSTDLESALQTKRRLQNELEDYRNQRAMDIEDKESSMEQTRKKYQTEFATLTKELDLAREEKLFKQAEITRLREELEELRSKWDDEVLNSSTWSKEKARLEGTLADVSSSRDEAVNAHNEAQGKIVTLLSQVRSLRSSVDEISAERDALAREKRGLETRFAEAKAGLDSLVSSEATGASIRDAASADKLILELKTDVAQKDDIATAAIEKMRRAEALATEAQKDAAVERDMCTKLAEQKASVEKKLREVQVKLVDLETKGFNSTRGDIKFLHKRIQELESQLEAKDEARSREARSVRNVDRVVKDLQDQIDRKEKQNAQLEDDLTRMNEKVEKLLKAIDELQASESASQLTSRRAERELRESREKLLMMEREVEAARGTTYGGPGTGGGAFARGSFRRHTGNAFTRLVENDHESGLTREPSLTKGFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM44</accession>
    <name>A0ABR3ZM44_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SWR1-complex protein 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000233</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037651">
        <property type="entry name" value="Swc3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057558">
        <property type="entry name" value="Swc3_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28108">
        <property type="entry name" value="SWR1-COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28108:SF1">
        <property type="entry name" value="SWR1-COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24707">
        <property type="entry name" value="Swc3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SWR1-complex protein 3" evidence="2">
        <location>
            <begin position="66"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="646"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="164"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="281"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="656"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="728" mass="78354" checksum="418A18BD73396D57" modified="2025-10-08" version="1">MDRKRKLPPRAASRIDHVSKKRTMTPDKDSTRSENATTAPATEPPPPQDSLTHLPTSTQPGKPLPTLGSLPLDDISTKDYQDYKETGVMAESLNRSRQKWIAEGLFEKYWVKPTKKKGVVVDDMKNPAKESMFKLGQVTICIEPHVFEATMFGIKDPKTAQKGSTTLSSTSQQQLNTTHRPILQYGPPNGTMPSKPAPTKTRQANEPGQQATVALVSPAVTTSDTLNSVGESHNGTSTPGPQIIQKPVLPVANPPPPNPGINQPLTQNANPPAPAPPGPASQPMGPATTPTAPPLVTPTQQPNPHQPPYRAQPPQQQAGSKTSDPVIVMLAEKASSDEHLREIMKKVAENRASLDELAHFQQVIDQITASQKKPSPPADRVIVDGRSVKYFADEVNVIIGVVLRSNPTQRAADLRPPNGSDPLVVALVKDALDKPLTTRAIISRIANGQPRFMDPQDLKSTLEELLKQLPKPRLAACASLPTSPATSSIVQTAIPAQASRAKLPSTAKPIPDISGVVFEFAGSNGDRYLFPRFSILDPVQVKLGGLQHVVASFLIVRKGSFSEYGGDPDLDYYQPVTIRISSQSGRHLENLARVVAPKNEVRRYMGDIMDNMTRAEYILLAMRLPRPSVSSSSLAVDKDDEVSMMALDDSGTSTPAAQGASRGTAAADTSVRNKLVNGGVLWGNRAGVHADAAGMAAKKSSIMTEEQERMDKYQKLINSAAAKDAEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMB6</accession>
    <name>A0ABR3ZMB6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleolar complex-associated protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_000522</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
            <location evidence="1 5">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the CBF/MAK21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005612">
        <property type="entry name" value="CCAAT-binding_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011501">
        <property type="entry name" value="Noc3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016903">
        <property type="entry name" value="Nucleolar_cplx-assoc_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14428">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14428:SF5">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03914">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07540">
        <property type="entry name" value="NOC3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028977">
        <property type="entry name" value="Nucleolar_complex_p3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Nucleolar complex-associated protein 3 N-terminal" evidence="8">
        <location>
            <begin position="134"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="CCAAT-binding factor" evidence="7">
        <location>
            <begin position="491"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="460"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="21"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="460"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="470"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR028977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="695" mass="77995" checksum="21C57F3CFA576307" modified="2025-10-08" version="1">MVAAGKRKIKRSEGLDNCPKASSSANDNAQSSNKTQKAFFKNATNWNLEQDYESRPRKRNKREKESTRLPIKTADGRLQHVTAPDVNDDAGHESEISDGDWLEGDSMDGSISELDGEKQEDKPEIPIPEQIRLAQEELAKIATSLTMDPEDHPGAFRALAKIGESKIVAIQKLAVMTQMTVYKDVIPGYRIRPAEEGSKEQLSKEIRTLRAYEQALVAGYQAYIKKLSHYAKSDPMGLSASRKKGSLGSIAIVCTCMLLKSVPHFNFRSELIKIVAWKLSRRKVDDEFVRCLDTLRELFAEDEDGRYGLEVISLVTKMMKVREFQVDESVVNLFLDLRLLSEFSGKASNERVEMEASGPKPKKVFFTKRQRKNRKEQKALDKDMAQAEAVVSHEERERMQSETLKLVFATYFRILKQRLPHLMGATLEGLAKYSHLINQDFFGDLLEALKDLIRHADNDANAELDGKTEENEEDQEEEEESAPTRNTSREALLCNATAFSLLAGQDAHNARNDLHLDLSHFTTHLYRSLLALSVNPDLEKTARSHLWDPTQPKPARVVPNKVNLQTTTVLLIRCLTAVLLPHWGIRSVPPVQLAAFSKQLMSSSLHMPEKSCRAVLALLTDVADTHSKKVASLWNTEERKGDGAFNPVSETIGGSNPFAATVWEGEILRKHFSPQVRDSVKLLERTIGGGNGRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPF3</accession>
    <name>A0ABR3ZPF3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Respiratory supercomplex factor 1, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">RCF1</name>
        <name evidence="12" type="ORF">Cpir12675_000230</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Associates with the respiratory chain complex III/complex IV supercomplex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RCF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007667">
        <property type="entry name" value="Hypoxia_induced_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050355">
        <property type="entry name" value="RCF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12297:SF3">
        <property type="entry name" value="HIG1 DOMAIN FAMILY MEMBER 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12297">
        <property type="entry name" value="HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04588">
        <property type="entry name" value="HIG_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51503">
        <property type="entry name" value="HIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="HIG1" evidence="11">
        <location>
            <begin position="5"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="129"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="162"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1901723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="215" mass="24834" checksum="79CFC3B9ECEE9C78" modified="2025-10-08" version="1">MSSNELPSSFEHDELYNERPMQKVWRKLREEPLIPLGCFATVFAFTGAYRALRRGDSKGANRMFRYRVGAQGFTVLAMIAGSIYYSRDRERTAELRRLEEQQNAEEKRARWLRELEARDAEDKEMRAALEARRRKRQERVLAEESGPSTSGEKSVFQALSKAKTDREAREKESKAAMTAADEDSEDATPFKQLGFLVAQKRKAKEEENKKSQESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPL3</accession>
    <name>A0ABR3ZPL3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000009</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895:SF67">
        <property type="entry name" value="AMIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="156"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="615" mass="66335" checksum="F702E7E929D8F8D1" modified="2025-10-08" version="1">MQPPNEPMRKRFINYPEPLEVTRHVPPIAQAKKNPVLVGIVLLISAKLMEWLGVLRRHIWNNTGFNRLNKHAETLLDYEPRYEPTVIPLESEEVAKGAAAPLENEILPRVKSGYYSASDFHHMYLAGELTPTAVATALLPLIRRDTTPQGPHSLAWFDSQVDRVLAAAEASTQRYRNGCPLGPLDGVPTAVKDEYDLEGYTTCLGSPNDYTSPPESGVPAVSWCALKLQESGAVILGKTSMHEFGLDTTGNNPHYGTPRNPYNSSYYTGGSSSGSAYVVAAGLVPMALGSDGGGSIRIPSSFCGVYGLKPSHNRLSFRPGPNHAITCAVNGPIASDMASLVAIFETVSVPHPGSSFSPMARFTMSPAIPDAKLIGIDETWNALADPANKQLCDTMVARLVAEKGYTVVPIRIPYATDGQIAHALTVLTDAATLLPEYQNLSAPNRILLALGRTSSAVDYLMAQKLRGLLMQHLAHLWKKHPGLMIASPVTGCAGWPIRSEAELKYGLNDGDTTLVSMQYTWLANFCGLPAISLPAGYVVPEGEVGAGRIADEHTLGKIPVGFMCAGEWGSEHALMRLGFDVEELFAQTRTRAQAWEDVVQLAKEEISGSGVLVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFN9</accession>
    <name>A0ABR3YFN9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_006685</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000351">
        <property type="protein sequence ID" value="KAL1887125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24399:SF70">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24399">
        <property type="entry name" value="ZINC FINGER AND BTB DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="401"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="429"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="102"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="198"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="105"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="130"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="199"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="209"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="274"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1887125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="473" mass="52472" checksum="FC56017EE46D455F" modified="2025-10-08" version="1">MNAPTDQADLAGLVHPPDVVEMPDFGHLSDFVAIPDSADFTGAAWVNPESSGVSMENVLMQHVYPLLLTTWAGMSSEGLSPASTNASSASPSSNPALSGYYSQMSSPWSNPNNNSYAYTTTPQHQDHQSHQPQHQQQQQQHHQQHQQHQQHQGQGHNQPNSQPSYQKLYDGSQMGYDARFSRSPGSNTEAILPPPYEVQQHQQPQQQETPHHQQEQHNQQEHHQNHHSHHSPQSTLNAPHHHNSPYARQSHVSLAPVHASHHQHASLPSPQPPTLASNGPNVSSANHPGQPISLDTYKIQSPIQTFCTPVTTTTTNPFSSYAAGAMQVSPSALSRNLPSLPHQHFGAMQHYSQPIPSIGRPISGMAGHGSHLSIMPAIPQHVPYMSPVDYIHVPTPSDRPFRCDQCPQAFNRNHDLKRHKRIHLSVKPFPCTYCDKSFSRKDALKRHRHVKGCAEKANNSLIREQDRRNPTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFS4</accession>
    <name>A0ABR3YFS4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Phosphate metabolism protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PHM7</name>
        <name evidence="13" type="ORF">Cpir12675_006675</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CSC1 (TC 1.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000348">
        <property type="protein sequence ID" value="KAL1887146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032880">
        <property type="entry name" value="CSC1/OSCA1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022257">
        <property type="entry name" value="PHM7_ext"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF26">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G10920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12621">
        <property type="entry name" value="PHM7_ext"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13967">
        <property type="entry name" value="RSN1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="403"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="449"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="494"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="543"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="613"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="655"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="683"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like N-terminal transmembrane" evidence="11">
        <location>
            <begin position="15"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="12">
        <location>
            <begin position="191"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="9">
        <location>
            <begin position="401"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="domain" description="10TM putative phosphate transporter extracellular tail" evidence="10">
        <location>
            <begin position="751"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="265"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1887146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="852" mass="94830" checksum="D020C13659208945" modified="2025-10-08" version="1">MADDTETGPASLQGFITTLAAGSIVAGIYLTIFLILRKSQRRWYEPRTYLGSLRSFERTPSLPSGLFGWLAAFWKMPDAYVLRQQSLDSFLFLRFLKVCIGICFVGILLTWPILFPINATGGGTQKQLDVLSMSNIDTSTETNRYRYLAPAIIACVFYGFVMYVILRECVYYINLRQAYLLSPQNSSRISARTVLFTAVPKDYCDETKLHRIFGDAVKNVWIVRDTKELDKIVEERNEVAFTLEKAEVKLLKMTNKARIKAAGKNRKDSTDGEKPLAPDTTVAAASPDLAEQLLPRKKWPRHLTGKLGISGSRVDSIPWCREQLAKLIPKVAAAQEAYKNAATDPIGAAFVEFHSLADAEAAAQSVIHHHALAMTPAVIGVRPEDVIWGNLGMPWWQRIGRRYIVGAILTAMIIFWAIPVAFVSSFSQITYLMNRYSWLSFLESVPSVVMGFITGLLPSVALAILMSLVPVIIRLLAKFSGEPTQSRIELFTQNVYFAFQVVQVFLVVTISGSAWSLLGELADNPSSLLTIVSESLPRASNFYINYFIVQGLAIASTTLAQVAGLVVFWILYRFLSGSPRAAYQKWTSLTTLSYGQLLPVYTNIAIISISYSVIAPLILFWAFTGIGMFYFAYRYNILFVANASLDTGGLIYPRALKHLFVGIYLAEICIIGMCAVSRAYPALAVAVALLVFSVLFQITVMAAIEPLLHSLPQTLQAEEIHALMNGRDAENAETPAEGTSSLKRSNPVVRFLMPWKYDNYEYFKSLVAPHLFPMQNYTAETEANSYFPPSVNDKVPLLWIPQDAAGISKQEIAATEGIIAMTDEGASLNEKGNIVWDNETARPPIWEEKIFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGL8</accession>
    <name>A0ABR3YGL8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ribosomal RNA-processing protein 8</fullName>
            <ecNumber evidence="8">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">RRP8</name>
        <name evidence="10" type="ORF">Cpir12675_006576</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
            <location evidence="1 8">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the methyltransferase superfamily. RRP8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000326">
        <property type="protein sequence ID" value="KAL1887372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106142">
        <property type="term" value="F:rRNA (adenine-N1-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2150">
        <property type="entry name" value="Ribosomal RNA-processing protein 8, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007823">
        <property type="entry name" value="RRP8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042036">
        <property type="entry name" value="RRP8_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12787">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12787:SF0">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05148">
        <property type="entry name" value="Methyltransf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6 8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 8 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="26"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="78"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="501"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="115"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="142"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1887372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="542" mass="58939" checksum="9FD2F569BB343E01" modified="2025-10-08" version="1" fragment="single">TLLDISMFTVKGWSVTPDKLRKESLTQAAANAASEAKASGEPTAPVKKPRKRKRAGAVSQIDVNVDNVADMWESVIEGKGTSKKAKKGAVSQQQIDKAAGDGNDVEGGDQAAPTKKQNQKAQTDVQAVDKQKSQPLLETKQSAKKMAKKEGRKKGQQSTQATLSSDPSPAPVPTPAPAALAPLPIPSAKLTPLQRAMRAKLIPARFRHLNETLYTRPSEEALELFSATPELFEEYHAGFRQQVEVWPENPVDGYVALVRERAAHRAPYVRRGAAKAEKPSYASLAVTPLPRTQGTCVIADMGCGDAKLAQALQSDTAGLRVRVHSFDLHSPSPLVTAADIANVPLDDGAVDVVVFCLALMGTNWLDFIDEAYRILHWKGELWVSEIKSRFGRVAGPANNAAPGRNVVSHSVGNRKKAAVVAKKPSKEDKEKQLVGQHKELAIEVDGEVDRRQETDVSAFVGALQKRGFVLHGEPDEAVDLSNRMFVKMHFIKAAPPVKGKNVDKYGKPANGQQKKKWPVGNDEHDEELDEDAILKPCVYKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGV0</accession>
    <name>A0ABR3YGV0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000318">
        <property type="protein sequence ID" value="KAL1887447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045319948" evidence="1">
        <location>
            <begin position="21"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="208" mass="23530" checksum="BD13F10A1D6BF878" modified="2025-10-08" version="1">MWLLNLSRLAFMAVIFSAQAIAGNKKVPLPSSLGIEISDGKYYGRKHVTSNVGFSARVFVTENLKSIQIEKIDNPGNIVKSYEAVLSIWKDQSKLTPESLEYISYYDVPILEIGIINEAMKAKGRNPFEENPIYGITISRDSVDDTEAWNHLITAPFAKDAEEICNQYEEMSNRFIESFRIGVDCDFNRWVSINFGRKGDQNTDNTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH24</accession>
    <name>A0ABR3YH24_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_006508</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000312">
        <property type="protein sequence ID" value="KAL1887522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="4">
        <location>
            <begin position="227"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="30"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="411" mass="45542" checksum="03FDE481A8860DD5" modified="2025-10-08" version="1">MASVLTLRSSLWALRQSAWSLSTRTMSSAAGAALSHSEPVSHATPPPSVPARHPKMPPSYEAVTGDLETFHLPTSVSGSLEDQILGQRLIAAFRRDGILQIRIPSMQQNIVDDAFVASKAFFRQPHAEKAALVDPYSYGGYIASGEEITDGIADYSEIYTVTKDVAPTDPRFKLPCHGQQPWPNKTFKDVVNRYMKQLGNTGDIMLGLAELGLNIPRGSLTKLSQDGWHHLRILRFPQNNKTNGKGKEGRGIGSHTDYGMLVIASQDDVGGLFIRPPHDDEKTQNWAKSAAGVKENDAGWVFVPPVSNVFTVFPGDMLQYMTNHYLPSTPHKVGLNTAERFAFAYFHEPHFDSVVKPLPGYNGGQEPAEGIHYGTHFTNMFKRNYPDRVTTQQLLKDGREAVLAQPEYRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI41</accession>
    <name>A0ABR3YI41_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Up-regulated during septation protein 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_006344</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000285">
        <property type="protein sequence ID" value="KAL1887993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056703">
        <property type="entry name" value="DUF7801"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029191">
        <property type="entry name" value="Uds1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43049">
        <property type="entry name" value="EARLY ENDOSOME ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43049:SF1">
        <property type="entry name" value="EARLY ENDOSOME ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25078">
        <property type="entry name" value="DUF7801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15456">
        <property type="entry name" value="Uds1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Up-regulated during septation protein 1" evidence="3">
        <location>
            <begin position="73"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7801" evidence="4">
        <location>
            <begin position="715"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="136"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="363"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="470"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="882"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="278"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="519"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="719"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="798"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="142"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="364"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="470"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="488"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="882"/>
            <end position="906"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF15456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="926" mass="104014" checksum="AB4751DE9757D48E" modified="2025-10-08" version="1">MTSYAQQQQQQPHLYQAPNGAHRNDSTTLSVPITGNLMADSYQNGNYPIESPRFPQPRPISTSFVDLKDPIQIHLLTETALADSRSFQIVSQDQVDVLKKQCQYISQRIEQTKANLALQTKYRDAAISMTKLYTPGPRRRSLTSNRSSLTSIAGAREAEAERETAEKRCEELAAELFQLEKRLVEPQRRLLEHTSAILQLTHRASHKKMMQQQLLNNPSGMHLFNGMPGSPESLYTYSTNRSSLASDDDIEFDTSKQFPKHHASGLEIPVKSPIREQTTRLREDVEQLKEDNARLVQENQLLKTSESKLDAINHAVRDLIIAFNPDENAEYPDQPRRGATGQLFIDTQLDYLEKGIQMARQEQEYSLSNSSSNGQRVDGDGNQSDNHTRLRSINGIVLAMLASAGADQPPSPGPTGNLLEDEISYLERAINVAEKELGPRGAVSISTTSGNVEGELKMIWDNMQSRAAFMKKDREDRKKQRAEKGLVDEDDEEAEDEDVNEPYSFIAFTSKVNFMATRVRRLAEEKVVLKRQIKQQRELNQKADAEEVLRLQGEVDNKQAEIIELRTQLAEVKDHLDSARAEISRNENLLQTALRDVEDLAQDRSIGQEDNAKAASLRTELETTKTQLNGLQQRATDLETRAAAAEASRADAEVARQQTEARLTHSEATRKDLEVQVAGVDTKISELSAQLAEAVTARAAINEALDSKQKEVDMRTRQVQEKEDLLESMNFMLAELKTELTIAQAELDGAYGSRAERAKDIAAMKSTLEVQKIQTETDTLRKELAATVKQLQEITSVSIAAETEKVEIEARLDDAEQARGTLESELEEVRTRLDKEVLAGRERMAKLQESLDEEKLKGGAAAGLAKGASMLSEQFRLTMREERRKFQDDMREEQTRRRKVEEELRQLRRAAGMRSPMTPAPPTGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI51</accession>
    <name>A0ABR3YI51_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cupin type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006405</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000295">
        <property type="protein sequence ID" value="KAL1887819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02231">
        <property type="entry name" value="cupin_BLL6423-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047142">
        <property type="entry name" value="OryJ/VirC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36156:SF2">
        <property type="entry name" value="CUPIN TYPE-2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36156">
        <property type="entry name" value="SLR2101 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-2" evidence="2">
        <location>
            <begin position="92"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="195" mass="21505" checksum="9617F34C3ED1595E" modified="2025-10-08" version="1">MKRPATENQLSESLPGPRTIITGHDSTGSAIIHEVRSVKWTSFQEDRLGLSVAYTTQFPVQLSDDADIHAHDALVDSGRLGLVNPNGTVLRYVDIAPGHECIMHRTQSVDYGIVLEGEVVAVMGSGEEIIMGRGDTMIQRATMHQWRNDSKTQWVRMIFCLQGCQDVMIKGKKLGEDLGVGMKGLLSSEKIENKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI90</accession>
    <name>A0ABR3YI90_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription factor RfeG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006363</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000288">
        <property type="protein sequence ID" value="KAL1887927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39609:SF1">
        <property type="entry name" value="RFEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39609">
        <property type="entry name" value="RFEG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="115"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="185"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="235"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="431" mass="46296" checksum="00D79A0115EB1807" modified="2025-10-08" version="1">MAHTATRAPATMAIQSNVPTRHNEYFIDRDGIDREVITADICRYLGNDALVRPGVFEDPSNGQQRQGYFITAYRNLTTAMIEDLKNDSIRWEKEKERANMASRKGYRNLGSPVHGANGSNNAGGNNNNSNNPSNTNNNNGSANGGSFKGHPLNSANTNIHNGPRRSNSPKTNSIAAPPPHPPQTPHGSSYQSSSTYSQRPEMPPMSNGGMPPHDYPDRRDVHDAPRYSSHHPQQYPGSAPPSGYGHPPPPPPPNGYTPQADQSYPGGPYPPPPPSMSSYSAPPTQAPYGAPPAPMPEYGQQPPYIPPGPNHQANVYPHDRMGASAPPPQSGYAAGQPPSYPPAPSGYQPPYPPPAGPNGGPSHYDAMKPPPMDPMYSRNSYQDRTNSPPSNNGPAPVPGDRQAPPMPSKSPQNYHNPYADARGPYSQPSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIG0</accession>
    <name>A0ABR3YIG0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_006296</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000278">
        <property type="protein sequence ID" value="KAL1888113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF54">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047286642" description="FAD-binding PCMH-type domain-containing protein" evidence="5">
        <location>
            <begin position="21"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="86"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="522" mass="54742" checksum="466C2141F3A83802" modified="2025-10-08" version="1">MTRFYTILGSALLLSRGSHAATSAITSADSCTTTTPKAQTTGSSAGDAGNNTDACSALASIVPNGVVLPSSDAYANSANYWATGPASSKPDCFVIPSTGAQVGEIVKLLIKKSTPFTVKGGGHTPYAGASSRDGGVVISMESMAGVQLSHDRSTVVVGPGARWIDVSRSLDPEGLSVVGGRIGDVGVSGLLLGGGLSFFSGKLGFACDNVKEYEVVLASGQVVVASPDSYQDLFWALRGGGGQNFGIVTSFRLRTVKTPGLWSNRNYIAGEPLIQQSISAFASLPPVLKEDTDAHAYLALVDAPGIGILATPSLFHPAPLQDNKWPATFAAFEKIPGLFNETVAGNISTIIGPTTPAPGSFQLWQTLTVKASSVDVLQDFYKIFVEMASETHAQLDAAAMPTIIFHTLTTKTLSLTGQNGGNPLGLSAASGPLWIIQVNLQWSDASKTEAAIEIAQKTLAKAQDAAKTRGVFESYEFMNYAYKTQDVLASYGSFNQAKLKMISEKYAFGGAINKLWTGHYQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIN6</accession>
    <name>A0ABR3YIN6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000280">
        <property type="protein sequence ID" value="KAL1888077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="449" mass="51019" checksum="3848EF1641A1FB06" modified="2025-10-08" version="1">MQPTRPEYQSRSAYHSDSRPHDSFHDLPDHHQALQRSHQEHSYYHQTPLQQHQQAPSHNHHKTQFHPSLKAKNNDPRNSVDFLTGRDTSTARANSSASAISTENSQSPSVSPRYNLSSVNHSSTSYFPTAESQAISHTGEHSKSHTNSVSLPSCKNLLEKVDKSMSFSAPRPGYSHGDSIPPSSYGHPHAADAPHYSYPPSATDSNSVAANCPQGKYISFGQSLPPDHPKHPMYHRYLEQSQQQQGQQQHNRTAHYQYQKHPYHNGVAHPPNFSQPSYEASGAPSQRQHSLSREQRGSKPRYNKEYTPEQIHFCLYTFIDKKLSWNETLDRYNKLFPSDQNRGTAGLQGVMYRENKVFPCTDKDGNLIYNPTTERFETSSFPIRSQGDKIGLLDRYPDAAIGYSWVDDADKERIWDIGMRQKKQRMQARQRQWAMDSLPSPLSSPGAQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIP0</accession>
    <name>A0ABR3YIP0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_006318</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000282">
        <property type="protein sequence ID" value="KAL1888048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1888048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="229" mass="25557" checksum="AA3E6899DF463A2A" modified="2025-10-08" version="1" fragment="single">PGISHDIQPSKTAELENAQVGAITTDVSDPQYLEAHGYVTWNAGNENYLVFSQVFGGPGLRTMLKISVNMEHKAVTIIENHLYREISRKERLGLPQIFQGLCHQQKIQCSEMKSIAMDIDDSFTYLDVETYRKINGLGSEQQIEIAANQPGWGIFSGAINYKYATEMFPGLEPESVIIKQDRRPSEDPKYTVVITEVIMVLFKQPGLKDEDAVVSPIDAHAAELSARTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJM2</accession>
    <name>A0ABR3YJM2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Malate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000262">
        <property type="protein sequence ID" value="KAL1888422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021851">
        <property type="entry name" value="DUF3455"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35567:SF3">
        <property type="entry name" value="MALATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35567">
        <property type="entry name" value="MALATE DEHYDROGENASE (AFU_ORTHOLOGUE AFUA_2G13800)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11937">
        <property type="entry name" value="DUF3455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045949662" description="Malate dehydrogenase" evidence="1">
        <location>
            <begin position="19"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="262" mass="27157" checksum="7E39B0DA2B40B07A" modified="2025-10-08" version="1">MHFSTVTFLAALVIHVHARAVTLQSRFPPSFNRTPKEQPALPVSGVSPELPAVPEGLVLKRVVLGHGYQNYTCSGEGATAEATGALAVLYDAMALYPGQSPFSVSLEQFLGLTGPALLQKAVPLATAPNTRVDQSAEGASADPFPVAPVAPLDLSAAGVQPPLPYAGVHFFDAQKVPRFELTRGEKLLAAKLASQPAPANATAGPNGEPAAPWLYIGDVGGSVCLTAGYRVKTAGGTPHTCSSAGDDSSVYTAYYFLYGPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKM2</accession>
    <name>A0ABR3YKM2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">37S ribosomal protein MRP4 mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_006193</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000263">
        <property type="protein sequence ID" value="KAL1888412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00291_B">
        <property type="entry name" value="Ribosomal_uS2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_uS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005706">
        <property type="entry name" value="Ribosomal_uS2_bac/mit/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018130">
        <property type="entry name" value="Ribosomal_uS2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_uS2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01011">
        <property type="entry name" value="rpsB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S2 PROKARYOTIC AND ORGANELLAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="Ribosomal protein S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00962">
        <property type="entry name" value="RIBOSOMAL_S2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="427" mass="47145" checksum="7B1EE0BF7984FA8D" modified="2025-10-08" version="1">MIIRKTLLRQGYRLAASSNTYYYRALTTGSSLPASTPTSDTPATQIPIPRQAIEAVEEEEDKGPKIPGKPVASYENSLVKELMKLANTDNNQAFRKNHVRNLNAEAQLSKLGSDLTVAYSATQMLKSPPTAQQVTLEMLMAAQTHMGHNAKVWNPANSRYIYGIRHGIHIISLEQTLAHLRRAARVVEEVAYRGGTILFVGTRKGHMEIVSRAATKAKACYLFTRWTPGSITNRDRLLEGLKVYAVNENDELLAGFEKHVDDSRPLTPDLVVCLNPIENYTLLYECGLAKIPTIGYIDTDADASWVTYPIPANDDSLRSATLLTGVLGRAGQIGQGRRLAEASQGICTWETPSEVAKFLEKTVRHRKKALSSDLTEAKTASISKTKRDGGDVDAQKELWKMVEAELLGHVESLPVEKLGPEDMMPEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKX5</accession>
    <name>A0ABR3YKX5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MICOS complex subunit mic19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006138</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000257">
        <property type="protein sequence ID" value="KAL1888517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012471">
        <property type="entry name" value="DUF1690"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07956">
        <property type="entry name" value="DUF1690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="157" mass="17404" checksum="EF763E35E5D4F2EF" modified="2025-10-08" version="1">MGASSSKISQEWKASGPTGVSHDLIESLQSSKETDLSRAKLLETHIEARVTAELAKLHDAENARLAAVQERLGAAPAETDESLTSHVVSKEIENLRVKLEARKNLRELPPSVEAARGSVVRCLREHDRRPLDCWKEVQAFKDEVKALEKSWVDKVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM18</accession>
    <name>A0ABR3YM18_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mannosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MNN4_2</name>
        <name evidence="7" type="ORF">Cpir12675_005878</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000225">
        <property type="protein sequence ID" value="KAL1889232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009644">
        <property type="entry name" value="FKTN/MNN4/W02B3.4-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007074">
        <property type="entry name" value="LicD/FKTN/FKRP_NTP_transf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15407">
        <property type="entry name" value="FUKUTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15407:SF28">
        <property type="entry name" value="RIBITOL-5-PHOSPHATE TRANSFERASE FKTN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04991">
        <property type="entry name" value="LicD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046145801" evidence="5">
        <location>
            <begin position="19"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="LicD/FKTN/FKRP nucleotidyltransferase" evidence="6">
        <location>
            <begin position="64"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="LicD/FKTN/FKRP nucleotidyltransferase" evidence="6">
        <location>
            <begin position="181"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="245" mass="28907" checksum="EE866DF5677E61B0" modified="2025-10-08" version="1">MRFLHLLGLAFAATPISAWKYFHEPGGSLELGHYDARYFNETVSYDDHLPALRYLIRSYLKTLREHNVETWIAHGSLLGWWWNGQIMPWDYDLDVQVSSSTLLWLGDNMNRTKHEYTYEENGKTQTKHYLLDINPFHSQLTRGNGHNIIDARWIDMSNGMFIDITGVAERDPVQSPGIWSCRNNHRYKTTDLYPMRYTEFEGVPTMVPYNFERILIDEYSVNALVTTEWLGHRWSPESKKWLKVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNG2</accession>
    <name>A0ABR3YNG2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PhoD-like phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005802</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000217">
        <property type="protein sequence ID" value="KAL1889402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="entry name" value="PhoD-like phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043904">
        <property type="entry name" value="PhoD_2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46689">
        <property type="entry name" value="MEMBRANE PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46689:SF3">
        <property type="entry name" value="PHOD-LIKE PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19050">
        <property type="entry name" value="PhoD_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoD-like phosphatase" evidence="2">
        <location>
            <begin position="234"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD-like phosphatase" evidence="2">
        <location>
            <begin position="443"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD-like phosphatase" evidence="2">
        <location>
            <begin position="538"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="731"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="804"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="806"/>
            <end position="816"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="828" mass="92639" checksum="B28066D6BFB4A268" modified="2025-10-08" version="1">MSHYARPTASSGIHASATDPNPDLDCSDDEQPVHYRSKRHGPGAYNDGPHADSHTSATRWRHQESSSYARHAVPRDLGAPRSTNDLADFLNSSRIEPPADANGNSGTAHQPIQLPPGIAAPLESQDPTQVLCGPMINYHGMADNGCWLGSVLVVTCGGGATVGNAPRLALTAVMPPRTAGPQMPEMLGTCLYSDPRCTFWQFSLEVPLLEVAARWRYEMPELHAKGSKKLPAREFYVPAATECMRSMFFSCNGFSIGTDEQAWSGIALWNDVMRRHKQEPFHVMIGGGDQIYNDSIRIQGPLREWTQISNPKKRRDHDFSDDFRRKCDNFYLENYISWYSRTEFAEANSQIPQLNIWDDHDIIDGYGSYVDEFMRCDMFRGIGGCAYKYYMLFQHHLPPPRYSYTTDKAGPEIQMANVYVAPLDNHVSSMYIRGPKPGPYIEQHAYHIYASLGPRMAIMGLDARTERTRHQINFPETYDLLFDQLRNKLATARNQGEPIKHLLFLLGIPIAYPRLTWLENIFRSPVMAPVKVLNRHFGVGGSLFNQFDGNIDLLDDLDDHYTAKTHKLERREMVERLQAIAAEFSVRVTFLGGDVHLAAMGRFYSNPSLKIPAERDFRFMQNIVSSAIVNKPPPQAVANLLAKRNKIHHLNKETDETLLNMFDRDPGSTACTSKNNHCTMPSRNFSILTENSPIRGIAQNGYGYHHPPASNAPATTQGSKFEGVSGHGPMCEDEFGAGTQHKAADSNAHGKGSDSSLDVVIYVEMEQSDREGRTCGYGVTIPALEYRGPVPNVWQTPFPSSELHHERFHRSKRGAHSHSDSSMTGISD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ15</accession>
    <name>A0ABR3YQ15_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005567</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000197">
        <property type="protein sequence ID" value="KAL1890024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="148" mass="16054" checksum="67B187AB11D84BB0" modified="2025-10-08" version="1">MSASGADTEVLQRTFLSRLDGWGKSSMPPAGLATLVTALHWRPLQPVPALVLSPALIFASYINVAGYPTDSAGLSAGVSGLYALLALRRKQKIRAKFLSTRGLVRGAALGMAVFNCAASSYVYSRGDRKEDMEMRVERNRWGEYGDKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR31</accession>
    <name>A0ABR3YR31_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Ergosterol biosynthetic protein 28</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Cpir12675_005431</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERG28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000185">
        <property type="protein sequence ID" value="KAL1890384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005352">
        <property type="entry name" value="Erg28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15451:SF19">
        <property type="entry name" value="ERGOSTEROL BIOSYNTHETIC PROTEIN 28 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15451">
        <property type="entry name" value="ERGOSTEROL BIOSYNTHETIC PROTEIN 28-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03694">
        <property type="entry name" value="Erg28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="8" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="11" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1890384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="170" mass="19288" checksum="BD8F6A88ABA0B053" modified="2025-10-08" version="1">MDTIINEWLPPAKGYLPYYMLSLSLIAIGNSAQNFMTLHYSRRMYNGRFVKNPKLGKASATFNPEDSVDKLVPALAGQEGLDQMTPVAARCFATWTFLTSIVRCYVSYHLSFGPMYDLGIWTYVVALSHFTLELGYFKTMKLGAPQLLPFMFASTGIAWMIYVRDFYVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR65</accession>
    <name>A0ABR3YR65_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Rab guanine nucleotide exchange factor S2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SEC2</name>
        <name evidence="5" type="ORF">Cpir12675_005410</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000184">
        <property type="protein sequence ID" value="KAL1890396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21044">
        <property type="entry name" value="Rab11BD_RAB3IP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040351">
        <property type="entry name" value="RAB3IL/RAB3IP/Sec2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009449">
        <property type="entry name" value="Sec2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14430">
        <property type="entry name" value="RABIN3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14430:SF0">
        <property type="entry name" value="SEC2P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25555">
        <property type="entry name" value="RAB3A-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06428">
        <property type="entry name" value="Sec2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144284">
        <property type="entry name" value="Sec2 N-terminal region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GDP/GTP exchange factor Sec2 N-terminal" evidence="4">
        <location>
            <begin position="146"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="11"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="292"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="594"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="631"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="704"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="206"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="33"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="48"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="296"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="318"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="663"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="676"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="704"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1890396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="741" mass="81172" checksum="354D9FD6D9878305" modified="2025-10-08" version="1">MNALMNMTAWTSYPAASGQSEAPSRTPRSFAHLRSFSQSLSLSVSGVAKQSQSTNSPASTRLDMTKASDVYDPDDESAHPQQSPPSPSGSVEAPSTPTDSAVLSTLPDPRMKFSLEPKDSQSEATVALENEVTTLSNKLIGAINHQTVLDNALTETREELSRAKESIHRLEGVVTKQREMLSGDVWIRKKAYEAEKCDLIAKIGEEKKLRLDIESEKKAMERELEQLSTALFEEANNLVIVAKEEAQREHDIILKKNDQLKAQVAETENLLRFQQDQLAELKHLMEQMKIEREDQASSATTTSSPRSSHVYSSREDLPSTTAPSNFLSPTDQSHPVAPASPTTLTHLITPVLRTDLSVYEDFKTLVNISHNYTNRLSGGSFFGNTSMTGASLNLGSMTGGVTSSAASILSSAASVHSTASTTTASMPHLKDLKFFKRVLVEDIEPTLRLDLSPSLSWLARRSVITAIMEGSLVIEPVHSNEPLTSVIHPHYYSCSLCGESRKSAEFLRTHRFRISETDSAQRYPLCPYCLTRMRTTCEFMGFLRILKDGHWRSEDPEDEKAAWEESVRLREQMFWARIGGGVVPVQHHQFVDSGRSPRISVDQAHGNTGLIEPDEDADVISVIEHNSELCTESPSATKITSATDNDTDDDDDGASVSSSKYDESDETCASETDAEPPVREASIKTKNDIDLPALAVAAQDYSDVSFSLTESSPAPSVYGDKIGDGQVCGHQAQSAVNKEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR92</accession>
    <name>A0ABR3YR92_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FKBP12-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">FAP1</name>
        <name evidence="3" type="ORF">Cpir12675_005446</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000186">
        <property type="protein sequence ID" value="KAL1890370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="entry name" value="R3H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034078">
        <property type="entry name" value="NFX1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001374">
        <property type="entry name" value="R3H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12360">
        <property type="entry name" value="NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12360:SF12">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR NF-X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01424">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00393">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="R3H domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51061">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="R3H" evidence="2">
        <location>
            <begin position="88"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="465" mass="52373" checksum="D5CC45B306BA8082" modified="2025-10-08" version="1">MSWNERSCQEKIQQFCACGHRKREIKCLAKSSDSIPNREPLECDNECLRFLRLQSIAEALGVDPERPVAAKDDYVYSDTTLDMFEQRTGWCGSQENEIRTFAVSQESRLLFKAMGRPSRTFIHMLAADLGLKSESQDPEPNRAVMVYKRDGRLPILPKVTLAEASRARAEKFRAKLAEKQSETFTVTSSPPKEPPQPSKLPTFFNTIAVKNVPFGMTLDELETLLTEALTSNPDLVFTSHFSENSSAYFRATHRSGMAPSSLQHLVTRIKNVAARVIDRHDLTAAVCMCTSDENFVVTHWDKKTSIDGWEHVGGRQKPLGNRIPRDQSMAAVAAAAVMNNKNHADATARSSNRSSKTLVLRRKAAPPNRFANRFILNKDDGDSEEGHDAGPNSTIPKEETTGLQAEDQNEGRTIVREMEEYDERRSSDETLHSTDNIETEQPPLRRLQPSPYEHLRCFSSSIDDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRF5</accession>
    <name>A0ABR3YRF5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Amidoligase enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000183">
        <property type="protein sequence ID" value="KAL1890467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022025">
        <property type="entry name" value="Amidoligase_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36847">
        <property type="entry name" value="AMIDOLIGASE ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36847:SF1">
        <property type="entry name" value="AMIDOLIGASE ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12224">
        <property type="entry name" value="Amidoligase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="406"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="410"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="662" mass="74396" checksum="0C2A4B772D0AB792" modified="2025-10-08" version="1">MSAITQESTVIKDDASSHLARIRPAPCSFGVEMEFLVAVLQDGAVDPMAHIEPNIPPVRVEKGASLSLAEAAAHRHVAQVLASAGLQVWDTPGTRHRDEILQVKAELRKEPFYMRRKTAARLAALKAAHWVVARDGSVKSDGLAHPLFWVGVEVQSPALWEDDMSMRHVERAVLAIRQGVRSRINQTCGLHVHVGRGDAQFELDELRRVAATLWAIEPMMSRLHPAYRGRENFSHVLRSRWRNKIAAGVGTAVTWAARATDKKQEVNRVLLANRNYETLDDLEIEVSPELANKVGVRLLENSFGSDVYRRMASDLAGIHGTPFNRPHTNVKIEEPEGSARYSLKRSRYEQQAASSEDSVDQEDMDSADDGRLLASPQGTKDESLPDINILKIVSDNVREGYAAAVKAPQATETHQPTSEEQWTQKTKQTTGAPLRVFPDLSKYIPHKLLIQPTDYAMLQEKRRVNGIYQRPRLPEIWPRKRYFPPRALRSLTCDYTGYASADYPGHDPTSMWWGVKELLGADISAEQIRASLMYEDQKYASYNFSRVGHFEQPSLLSQTIEFREAAASLDPAWIRTWATVAVGVVNWACRVNMSEFMQVMQLVSLVQSSDQVVPDGSKVEYDIVSFLEDIGLPQAARFCLKRLERGEEAMIECPTFEMYRGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSA4</accession>
    <name>A0ABR3YSA4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Multicopy suppressor of BFA (Brefeldin A)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">BFR1</name>
        <name evidence="3" type="ORF">Cpir12675_005051</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000159">
        <property type="protein sequence ID" value="KAL1891233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039604">
        <property type="entry name" value="Bfr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31027:SF2">
        <property type="entry name" value="LEBERCILIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31027">
        <property type="entry name" value="NUCLEAR SEGREGATION PROTEIN BFR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="58"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="372"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="433"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="249"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="382"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="442"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="466" mass="52188" checksum="C888958EF3F78F8A" modified="2025-10-08" version="1">MATQTVTPADAPAPASDVKVKPSKPNEDLFKKELAQAEANHKVAMDNYNAIRDKIDLAFPNKKNGAEESSPEKKRRQDLINERNEIRKAQAGSKSSRAAKLDQIKRLDEQIKSRTAEQKAARGKVAFKTVEELDARIRELETQVNSGTMKIVDEKKNLADISSLNRIKKNFGQFAESQKQIDDLRAKVKEIRDSMGDPEQKAISERYATIQAELDTMQSKSDEVFKNLSTLRDEKKKLHLEQQATYAAIKQLKDDYHNAKRAYATYEQEQRAKHRERIRAEREKAYKDAQKARAQEMLQTASLPAFADQIRLATSLLKFLDPSAVSDAKAPLLADRGLAATDIRKVDASAAPKGTVLVRKEDRDEEFITSAASKKGKKNKKATTTSASESARGFNCPPSVVQDCSYIGVEPPMSAAEVPSVIEQVKAKLEEWKNNQAAETQKNMEKAKKEIERLEQEDEAERGTDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSD5</accession>
    <name>A0ABR3YSD5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Beta-phenylalanine transaminase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_005177</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000166">
        <property type="protein sequence ID" value="KAL1890987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43713">
        <property type="entry name" value="GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43713:SF3">
        <property type="entry name" value="GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="454" mass="48894" checksum="D5F3F0F16DE8E6C3" modified="2025-10-08" version="1">MDAQATPNSTAVDAAYRAAEARYIAQNNKSQLLYENATGYLPGGNTRSALFFAPFPLYISSANGCTVTSVDGRVFTDLLGEYLAGIYGHTNPILQEELHAAISNGLSFGGHHVAEAELAAEISRRIPSIDLLRFTNSGTEATMMALATAKTWTGRDKIVVFRGGYHGGGFVFRGGNNLVNVPHDYLVAEYNDDGSVQAIFAEQGPNIAAVIIEPMLGSGGGVRARKEFILLLRALTRDAGALLIFDEVMTSRLFDGSGLQGLLAVSPDLTTLGKYVGGGMSFGAFGGRRDIMSLYDPRGGKDNFQGVNNCSTPLPHAGTFNNNVLTMRVGARGLKDVYTRERATELNAFGDKLRERLNELAAVSGSTMKVLGCGSILVFHFTKTEMMNIHGPADWADEDDRLLDLLHLTMLEAGFYMGRRGYVSLSLAVGDEEATRFAQAVGEFLARYEDLVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSX8</accession>
    <name>A0ABR3YSX8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Small nuclear ribonucleoprotein E</fullName>
            <shortName evidence="11">snRNP-E</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Sm protein E</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">SME1</name>
        <name evidence="13" type="ORF">Cpir12675_005094</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Involved in pre-mRNA splicing. Binds and is required for the stability of snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site. Involved in cap modification.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000162">
        <property type="protein sequence ID" value="KAL1891125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01718">
        <property type="entry name" value="Sm_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027078">
        <property type="entry name" value="snRNP-E"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11193">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 11" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8 11" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 11" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="12">
        <location>
            <begin position="17"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1891125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="94" mass="10490" checksum="1993B71853064EC3" modified="2025-10-08" version="1">MTGRGGGGGRRVLLPPINFIFKLLQSHTTVQVWLYEQLGIRIEGKIRGFDEFMNLVLDDAVEVKIVSKTNPEETRKPLGQILLKGDNVSLIQSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT52</accession>
    <name>A0ABR3YT52_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Iron-sulfur assembly protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ISA1</name>
        <name evidence="4" type="ORF">Cpir12675_005125</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HesB/IscA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000163">
        <property type="protein sequence ID" value="KAL1891117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="ATAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="ATAP_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050322">
        <property type="entry name" value="Fe-S_cluster_asmbl/transfer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017870">
        <property type="entry name" value="FeS_cluster_insertion_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00049">
        <property type="entry name" value="iron-sulfur cluster assembly accessory protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10072:SF41">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY 1 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10072">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01152">
        <property type="entry name" value="HESB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core" evidence="3">
        <location>
            <begin position="204"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="69"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="155"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="76"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="307" mass="32815" checksum="CB9D72B57E9B9C96" modified="2025-10-08" version="1">MLTSRSLARLARPALTASLLPSYGFVFSQCLCSTQHARLASFQPHRLTPSALENAASLSSVDAGKLAKANNHKSISRTPDRQSATPPSLPQKNIQAENQTRTQVLGQAKASEVPELHPQAAHSTPASHPDSPAILPSATAFATATANIPATATAATTATTATPHTPTPTTKSPSPTLGATSPTTPSVKPPARKSRLRMPRKAAIKLTPAAIEQLRDLLDQPEPKLIRVGVRNRGCSGLAYHLEYVDKPGQFDEKVEQDGVMVLIDSKALFSIIGSEMDWVEDNLLEKFVFKNPNIKDQCGCGESFMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTR5</accession>
    <name>A0ABR3YTR5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Peroxisome assembly protein (Peroxin-2)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">PEX2</name>
        <name evidence="17" type="ORF">Cpir12675_004848</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the pex2/pex10/pex12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000147">
        <property type="protein sequence ID" value="KAL1891775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025654">
        <property type="entry name" value="PEX2/10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006845">
        <property type="entry name" value="Pex_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23350">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23350:SF4">
        <property type="entry name" value="PEROXISOME BIOGENESIS FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04757">
        <property type="entry name" value="Pex2_Pex12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Pex N-terminal" evidence="16">
        <location>
            <begin position="99"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="465"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="470"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="485"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1891775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="509" mass="55938" checksum="5C6810D81010D4D8" modified="2025-10-08" version="1">MAPFTGDLGHPTASLPVPKFNFVQAQDRIAARRSAREATYRTQIAAAHNSSALRQRLTALPGPLSCLTGLYDVLAGSPMPGVTSRPNFRVGQVDAELLDNELVDLLRGQVGEALKYVAGGHIKDDYSAEIGLMLRAALFKLTIWDHDASYGAALQNLRYTDARGYTNGGVLVPPSRWQKTAYGAVSVLGTYGWNRWEQWLMTQDDGFNDPAPAVQRLATLTNTAGALHSMAAFASFCAFLVHGRYRTLLDRILRMRLASPSSQVSREVSFEYQNRQLVWHAFTEFLLFVLPLIGVSRWKRWLARLWRRTKQVLRTRGAAADGDTDGMAKKTGELSFLPERTCAICYHAQNAAASEAEVLASSAAGGAAGSAAKDITNAYEAVPCGCVYCFVCLATQIDREEGEGWTCLRCGELVKECKPWNGDVLEPARTATKTVTFRDDPREYSEREYSDNSVLPGLAVVPPVPLLDDGDLHSEESNRDGHGLDDEDILVEDEEDEGLVEELGEELDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTS2</accession>
    <name>A0ABR3YTS2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glucose repression mediator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SSN6</name>
        <name evidence="5" type="ORF">Cpir12675_005030</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000158">
        <property type="protein sequence ID" value="KAL1891240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051630">
        <property type="entry name" value="Corepressor-Demethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14017:SF1">
        <property type="entry name" value="LD02225P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14017">
        <property type="entry name" value="LYSINE-SPECIFIC DEMETHYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12895">
        <property type="entry name" value="ANAPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="53"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="121"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="157"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="194"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="231"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="303"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="337"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="417"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="449"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="499"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="520"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="541"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="558"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="571"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="583"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="611"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="656"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="713"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="729"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="772"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="872"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="899"/>
            <end position="910"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1891240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="932" mass="102480" checksum="52A54B17DEC7CEFF" modified="2025-10-08" version="1">MAAHHSPSMMQIQQQQQQQGAPHVAPPPPAAAPPGASNRFAGVPSQQVSAMTEAVWMQIGSFAELVGSPDEAMQAYENALRANRNSIPAMNAISLILRTREEFHKAVEYLQAILKLDSNNGEVWGSLGHCYLMMDDLQEAYTAYQNALVNLPNVKEPKLWYGIGILYDRYGSLEHAEEAFSQVMQMQPDFEKANEIYFRLGIIYKQQGKYAQSYECFKWIVTSPPHPLTEEDIWFQIGHVHEQQKDYDNAKAAYLRVLDRDPAHAKVLQQLGWLHHQQSNSFSSQERAIEYLEKSVAADPSDAQSWYLLGRCYMSQQKYPKAYEAYQQAVYRDGRNPTFWCSIGVLYYQINQYRDALDAYSRAIRLNPYISEVWYDLGTLYESCNNQIADALDAYTRASELDPTNPHIKARLQLLRNGGSAPGSAPQPADVHPYQHQTASAPGPPNSWAPQSQPGQGHPAAPPPGSAQGNGWGSRLSGINPQPGNPYDQRPPAEGFRGPAPPMARPPSPRSEQMRPQGPPTSQAHPTQGPQGSHQSPYDARGPDPRGELRPDPRPDPRGPPPLRRGPSPPRAGQGPQGTSGPQGPPGPPGPPGSQNHYPQGPSSLPHHQPSPAQNMNMPERVQNPNYTSHSGPSSATEPGPPKPLPSFRPASSPRTDGRPIHDNRMPSPKSAYPQHQPPPPQYHSEGPSGPNHGPMDVAPPHPSQTPTMGPDPNHRRVDDHGPPLGSKRNRDWDEESVPKKQASEESRARMDDIRHRRPSTPSRENYGRSPIETRRGDELRRPDEPPRHNESYHQGDTPRGPGAAAGPENHSMPAAQLSLQSTPQMQPMPPHEQPPQNGSGSRDYPPEERPMEHTPAASASRPQPPASQHPSEPERAARKVDVNEDYDDSEDEDKKPVAPASGSASTAGPDLKKSPSTSGIKNILGPKSESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTU8</accession>
    <name>A0ABR3YTU8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_004830</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000146">
        <property type="protein sequence ID" value="KAL1891789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16180">
        <property type="entry name" value="EFh_PEF_Group_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051426">
        <property type="entry name" value="Peflin/Sorcin_CaBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46212:SF3">
        <property type="entry name" value="GH27120P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46212">
        <property type="entry name" value="PEFLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="113"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="172"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="208"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="45"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="87"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1891789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="274" mass="30799" checksum="0448F2D01C30016D" modified="2025-10-08" version="1">MAYNKPFNPDELPRFAEPEPKGGSHQSSSGPSSSYQKPAPPLPHPQQRQQSIPHQQPPMHHSHHPSRDQYTMSPPPQPTGPRPVANTAPSANRPPTSPNDTNAPGADATMLPLFRAVDKDGTGQLSEKELGAALVNGDWSSFDPQTVRMMIRMFDSDRSGTIGFSEFCGLWSFLASWRTLFDRFDSDRSGTISLPEFSNALVAFRYRLSPSFVETLFDSFDKRRNGMMSFDLFVQACISLKRMTDAFKRFDDDRDGYITLSFEDFLGEILRQMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU55</accession>
    <name>A0ABR3YU55_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">V-type proton ATPase subunit F</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">VMA7</name>
        <name evidence="10" type="ORF">Cpir12675_004754</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1).</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Vacuole membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the V-ATPase F subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000142">
        <property type="protein sequence ID" value="KAL1891923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10580">
        <property type="entry name" value="ATPase, V1 complex, subunit F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008218">
        <property type="entry name" value="ATPase_V1-cplx_f_g_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005772">
        <property type="entry name" value="ATPase_V1-cplx_fsu_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036906">
        <property type="entry name" value="ATPase_V1_fsu_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01101">
        <property type="entry name" value="V_ATP_synt_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13861:SF2">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13861">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01990">
        <property type="entry name" value="ATP-synt_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015945">
        <property type="entry name" value="ATPase_V1_F_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159468">
        <property type="entry name" value="AtpF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR015945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="123" mass="13701" checksum="C34A3ACEFBD28B4C" modified="2025-10-08" version="1">MASLADYKDRQFLAVIGDEDSVTGLLLAGIGHVTSGADTQKNFLVVDGKTETSAIEAAFERFTTDRKDIGIVLINQHIAERIRHQVDSYTAAFPTILEIPSKDHPYDPEKDSVLRRVRRLFGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU71</accession>
    <name>A0ABR3YU71_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_004932</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000152">
        <property type="protein sequence ID" value="KAL1891560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12577">
        <property type="entry name" value="RRM1_Hrp1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12330">
        <property type="entry name" value="RRM2_Hrp1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034156">
        <property type="entry name" value="Hrp1_RRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48032:SF6">
        <property type="entry name" value="RNA-BINDING (RRM_RBD_RNP MOTIFS) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48032">
        <property type="entry name" value="RNA-BINDING PROTEIN MUSASHI HOMOLOG RBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="83"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="156"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="309"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="309"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="323"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="340"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="357"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="377"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="418"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="432"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="452" mass="48786" checksum="38AED290D02801CC" modified="2025-10-08" version="1">MFIGGLNWETTDESLRDYFSQFGEVLECTVMRDNNTGRSRGFGFLTFKDAKTVNIVMVKEHFLDGKIIDPKRAIPRDEQEKTSKIFVGGVSQETTDQEFREYFAQFGRVVDATLMMDKDTGRPRGFGFVTFESEAGVENCINTPLEIHGKPIEVKKAQPRGNLREEEDASRRNKFRKMDDQGISGGNGSGPCAASPGGPMMGQMAGGSGSGMTPQVMAQYMQRMQQYFSMMQQQQMAMSRGMGQMNPAMYQNMQQQMMQMQQMHMAGRGQGGMNPAMMSQIMGQMGQMNNQMGQMNNQMNNGMMNNGGAGRGFNGGGGMPQGSFEQQNNGPMFNQQRRFNNGGPNQAVNNWNNNTNNGGGGGGGNSGTPEAYDDSMQQGGSSQGPNQGPNQAGRGGPSFRRMPGSQTPDPTNAPPANAPTGPKNAGKPGANYRGGGRGGGGGAGRGFHPYSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUG4</accession>
    <name>A0ABR3YUG4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004717</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000140">
        <property type="protein sequence ID" value="KAL1892028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045516835" evidence="1">
        <location>
            <begin position="19"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="115" mass="12077" checksum="327BC53D3938A986" modified="2025-10-08" version="1">MHLSLRTAFVSLLTLANAASLERPGTAINRRSPAIEARQSQGVNANRPVPTGACCVANTSLKQDVCSVNGQSGRCVPASVNNCGSVLTCIEDNRLTCDPEVLERGRPLCRLANGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUI9</accession>
    <name>A0ABR3YUI9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000140">
        <property type="protein sequence ID" value="KAL1892041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04513">
        <property type="entry name" value="Glycosylasparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.30">
        <property type="entry name" value="(Glycosyl)asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000246">
        <property type="entry name" value="Peptidase_T2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188">
        <property type="entry name" value="L-ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188:SF6">
        <property type="entry name" value="N(4)-(BETA-N-ACETYLGLUCOSAMINYL)-L-ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01112">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047247701" description="N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase" evidence="1">
        <location>
            <begin position="21"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="346" mass="36591" checksum="918681FEC5518609" modified="2025-10-08" version="1">MRLLHLLPSLCACLINTGSCATLPFVINTWGGPFTVTTDAAFVALKSSATALDAAESGASACEVSQCDGTVGYGGSPDERCETTLDALIMDGTTMNAGAVAGLRRVKNAIGVARRVLEDTQHTLLVGDHATAFALEKGFLEVDLATDESRSICYAWKKNNCQPNFRVGFGSKSCPSKEPYTPDFPPTKHNTPSITHSFPQPHDTVSVITISELGQMAAATSTNGAAHKVPGRVGDGPIAGSGSYVDGEVGGCGATGDGDLMMRFLPCYQAVENMRRGMSPSMAAEDAVRRMLRRFPLIQAGLVVVDKNGRFGAAASNWVFTYSWRSGSMSNSEVVTVQPIEVLNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUS4</accession>
    <name>A0ABR3YUS4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004826</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000146">
        <property type="protein sequence ID" value="KAL1891785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="396" mass="42917" checksum="4AC8CDD818094268" modified="2025-10-08" version="1">MSSLSRAFTNRRVKISLDIKENKDFMSRSSSTRKHNSNTARPKISGPVQLVHTTNMLSYNAPDIETTRRIPSSSSQNSAKSDVEYMSSPASYSASTVSTAPTSPESSICERPTTPEMFDIGPSSVSKNMNISSPISVPIRSDSKHMNISSPISPPVRSDSRAMKISSPISGPMRSDSKHMKVSSPISPPVRSDSRHINISSPISAPTMSDMPPAIPRRAPSHTKKASIDAVRQRSGSFTPAHYAPASSHHPVSRSVSTATPSSPNRSIMSKSSMTFSRASITSTSTAATSHSSFAAAKSPPMPSRPLYVAESPYESRQAEMSPFGQELAQVAEIAEEFGVKHRLEVIDEEERELHARGLYAFAPEDYLQEIKAIRLSFFPESVIPNGGARPAAVWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUU0</accession>
    <name>A0ABR3YUU0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_004654</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000137">
        <property type="protein sequence ID" value="KAL1892146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF10">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="20"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="64"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="140"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="201"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="624"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="112"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="238"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="635"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1892146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="831" mass="90046" checksum="173398A3E2F7F851" modified="2025-10-08" version="1">MAPPDAEAEERPYRSHLRPACHQCRRRKSRCKIEVGAAVCLMCRVHNTECVFPPLTSATPARIRKQNARKNSQPPHPPSSAPAQTQPSTSAPLPTSRPGSAVHSVDSDGTQHHSSPASSYAQTNSQAHMLLPARALPAQMSPVPSLGGPQGLPIGPVSVPAQNQASSPHELRHGLVSKPGLRKSLPDLGLASSAMPQPQSGVMAGLASGPTSGLLAGPGAAVTPPLGHEQPPKGPLTGHTNSPETSKQTSLLLEDEDGGNAHIIGPDVTRDSQVLADYLAMMHPSTGVMRVIKPQATTQGGPVIFARVKRQPLGMVMSTSPSAKKLKIVEKLLEPWNKQLLQLFFRKHNICLPMLNEESFLHQVFNAKERVSPALICCIYAQSLVYWGADPDLAKHHRPDPTFLWKLASEALFSELHQSPGISTIVALVLNVGGRPTSSMLGNQVQLGSAVSLAHSLGLNRSPMSWDIAESEKGLRMRIWWALNITDAWSSLGYGTPPHLKRSHSDVPPPSLEYLGITENSPQRDRDAIEVFMVLFSLTELLYRYLDRVYNLDRSPPAAASSGNILLSDIMHDLERWVDSLTGNCRKIIIRGTELDTPGAANLRLSYLSLRLLTQRIELLGDRGEPECGDPAGRAPSTSVPATATSAPATSALQQGPDGDARNRYIASRRTAEDIVLFAQELSAAHFSDFWQPVSTFIFASTVTFLLRCALEIDAPATSVGASLSQSSSLRMAQDLLKALRHHQENYEWDLAELPLAQHTEVIEKLMNSHKPAPGGAEGMVDDELVVHFGAGAFDWPNIFPESSFFNSFMPAGNWDQMFTDPSYGVEMGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUX1</accession>
    <name>A0ABR3YUX1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_004868</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000148">
        <property type="protein sequence ID" value="KAL1891682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45188:SF2">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45188">
        <property type="entry name" value="DNAJ PROTEIN P58IPK HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="141"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="187"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="225"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="4">
        <location>
            <begin position="313"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1891682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="451" mass="49812" checksum="2CBDDFB270B619CA" modified="2025-10-08" version="1">MSSNKLEAALEDCSMASKLDPTNSKILLRLARIYTGLGRPDDAIICFSRIQPPPSTNEMRMAKNMRQHVTAAQDALRNGTAGSMITHALDQAEKYLSPGAPKPRKWQLMRAAAYLKMGSPNSLGEAQTIVMNLLRSNPQDPEALVLRGRALYGQGENDKAIQHFRQALTCDPELSDAIKYLRIVQKLDRMKEQGNNEYRSGKWQAAIDRYTEALTIDPTNRGTNSKLLQNRALCRIKLKEYDEAISDCEKAVGLDPQYLKARKTKATAYGQAGKWEDSVREWKSIHDLEPEDRSILKEIRKAEIELKKSQRKDYYKILDVDKSADESAIKKAYRKLAIVHHPDKNPNDPQAEERFKDISEAYENLSDPQKRAAFDNGDDIDMSDMFNGGMGGMGGMGGMGGGAHIDPEFLFNMMGGQGGGFRGAPGGFGGGFGGQRSGGGFGQGGGFHHFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV89</accession>
    <name>A0ABR3YV89_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DNA-binding transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">AZF1</name>
        <name evidence="10" type="ORF">Cpir12675_004796</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
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            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000145">
        <property type="protein sequence ID" value="KAL1891792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="Classic Zinc Finger"/>
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        <property type="entry name" value="Zinc_finger"/>
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        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
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        <property type="entry name" value="GASTRULA ZINC FINGER PROTEIN XLCGF49.1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PR DOMAIN ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
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        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
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        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
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        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
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    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
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            <begin position="396"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
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            <begin position="426"/>
            <end position="455"/>
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    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="484"/>
            <end position="509"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="8">
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            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
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            <begin position="119"/>
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        </location>
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    <feature type="region of interest" description="Disordered" evidence="8">
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    <feature type="region of interest" description="Disordered" evidence="8">
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            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
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    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
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            <end position="29"/>
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    <feature type="compositionally biased region" description="Low complexity" evidence="8">
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            <end position="173"/>
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        </source>
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            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
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        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAL1891792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="677" mass="75192" checksum="6C49FD365642CD5B" modified="2025-10-08" version="1">MSTAPGPGPNTAPNWGRWPEDQQHQHQHPEYMLVNGSQQSSAHHQQSGQHSHSHAIPHHQPSQPQHHTTLPHPQQQQQQQPSPIYHMVPNQNTPYPGVASAATPISMAPSISRLTPPAYSPPQSYAYPGGYVGEQQPHHHSQQHPQQPQQQHYIQLPHPNPQQTYVHDQPQSSVKHERSAMRMLSPKSMRSPSNARSPVSLPESPESVSMPMSMPIPMNIPMNMATAMPLSVGMQYHDRSHEMRQNHQSQQQQQQQHYTQQPSSASSSRRPSTVANPLFREIPSANSKTVLPNVCLNPDHSVEFKTVVDDLMKAIQVPEEKESAVPFAPSAPHDMARSPGQLPVTASSPIAPSSMSTGHAVASQGYPIASMPMSAVSSPVSSSGRVGKRSKSRTRHYCTVEGCNRSFGQKSHLDIHHRAHTGEKPYICSAPNCDRRFSQLGNLRTHERLHSGDRPYVCEQCNKAFSARGKLKSHQTIHNGERRFVCKLENCNKGFTQLGNLKAHQNKFHEATIKMLTSKFCKMSSAERANLADPDVKVWEYFATLYKNSNKGIKGRGKGRKVSVIRSTNAAASGSIPASATVAPASAPMPMGMAMDMGAGATPYQQHQQQHQHQQHRQHMIGQPQAILPYDTHMRMSTARPMDDYAAVGPSPYDDQEARPMADPSVYDDERLRRMHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW08</accession>
    <name>A0ABR3YW08_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">rRNA biogenesis protein rrp5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RRP5</name>
        <name evidence="7" type="ORF">Cpir12675_004746</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000141">
        <property type="protein sequence ID" value="KAL1892020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="S1_Rrp5_repeat_sc11"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="11"/>
    </dbReference>
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        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
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        <property type="entry name" value="HAT"/>
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        <property type="entry name" value="NA-bd_OB-fold"/>
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        <property type="entry name" value="Rrp5"/>
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        <property type="entry name" value="Rrp5_S1_rpt_hs11_sc8"/>
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        <property type="entry name" value="Rrp5_S1_rpt_hs1_sc1"/>
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        <property type="entry name" value="S1_domain"/>
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    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 11 PRE-RRNA PROCESSING PROTEIN RRP5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PROTEIN RRP5 HOMOLOG"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="4"/>
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        <property type="match status" value="4"/>
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        <property type="match status" value="13"/>
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        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="12"/>
    </dbReference>
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        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="11"/>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
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        <location>
            <begin position="156"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
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    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="557"/>
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        </location>
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    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="651"/>
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        </location>
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    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="739"/>
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    </feature>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="835"/>
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    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="932"/>
            <end position="1010"/>
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    </feature>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="1042"/>
            <end position="1113"/>
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    </feature>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="1129"/>
            <end position="1198"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="1223"/>
            <end position="1292"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="1312"/>
            <end position="1383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="199"/>
            <end position="228"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1391"/>
            <end position="1486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="204"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1407"/>
            <end position="1440"/>
        </location>
    </feature>
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        <location>
            <begin position="1454"/>
            <end position="1474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1892020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1792" mass="195450" checksum="A76A4F93CFF31D7A" modified="2025-10-08" version="1">MSALKRKEAPGVGANPPSKSAKTSKSPQTKKRVNVTTASAVASTAAGKKTTNAFKNKANEVVSAPTKSILASLREEEPLFPRGGGSVLTPLEQKRIGLEAKADALAEDELLENSSTKAIALKKDRGPKRAKADGKLLKDPNAVKIEALNFKKVVKGSLILAQITEVKPLSLTLDLPNNLTGTVSITYVSDTLTQRLQAAANAEENNDDDDGDDDNDDDNGDSDGSSANVDLQQLFTVGQYVRAAVLSTNDGAGKSRRHIDLSLRPSDCNAGLAHDDLVPNSMVMASVVSLEEKGCIMDLGISNHDVRGFLPRKELDKSIPEERLQPGAVLFCQVTGKTGKVAQLTTQAAKISSVKNTPHEATTINTFVPGTVVDLLIVGTTWGGLYGKIMGSLDATADLIQSGVGPLSVNLESKHKVGSKIKARVIYSFPSTTAQKVGVSLLPHILSLECKKIGGSMPTKSLPISTFVNEAVVKHVETEMGLFMDIGQTGFRGFAHISAVSDEKVDALFESSGPYQIDSKHKARITSYNAMDGMFQLSLQPAVLARQYLRMEDVPIGAIVDCTVENVPVGPDGVTGVVAKISPGIVGFIIAKHLADVELQNPEKKFRPGVSIKARVLALDLQSRKLRLTLKKTLVNSDAPVISTFDQAVVGLRIPGTISKLMPHGAFIHFYGNLRGFLPVSQMSEALIKDPSEHFRVGQVVSVHILDADPEKRRLVVSCRDPSAFGIDKQNALKNLKIGDSVSGKVMEKAEDMVVLELGDSGLKAFLPLGHLSDKSGSKNRAILKKLHVGQSISDLTVLEKHEHRHAITLTQKPSLVKAAKEGNLVQDTTQIKVGSTLAGFVGHITSTAVFVRFAAKASALLPKSRMLAEIREEPNFGFELLQSVSVEVVTANAEQGRPVVVIAGTKTEQKPKADSMAMPTFEGITGDFGFGTLLKAKITAVKTTQVNIQVLECSELQGRVDVSQLYDSLSDIANVKTPLAHLSKGDVIPVRVLGVHDARNHSYLPISHRYKAHQVLELTARPSDLAAEKPQPLSFEQIKRGSKHLAFVNNSDKHGVWVSLAPNVGGRIAAVDLSDDMTLLSNIRLNFPVGMALMVNVTSVNVERKLLGLSVRSEAERKKITWDSLQIGTVLPSRVTKVSDRQVLVKLSEEVSGPIHLPDLHDDFDQARPQNFKKNDLMRISVVDVDVSNKRVRFSARASRVISSSSAVTDREIIAFDQLTVGDIVRGFVKSIADGGLFVLLGGNVTARVKISNLSDKYVKDWKAAYQIDQLVRGRVVSVDSESQRVELSLKETVLSPNYVPAKSWHDLKKGMVLAGHVRKVEDYGAFVEVENSDHVRGLCHRSEMAEQAVADARKLYNEGDRVKVKILSINMDKKRVNFGMKASYFECDDSDNEDIEMGGVSLETDGQDVEDASEIEGDEEENNDDEEDEDENDSEDENITVPQSSSKHYDWAADPFAQSDSDSDSDVGAAAKKASKKKKAIQTDKTASLDVNGPKSAADYEKLLLENPDDADLWLEYMALPLQLGDVTKARDVAERAIKTVNVREEMAKMNIWLGYINLEAEFGTKDRLEAVFQRACQYNDEQEIHARVASVYIQTQRYEQAEAIFEAMAKKFGAVSADVWTNYAHFLHATLGRPDKARALLSRALQALKDTRVHLPLTVKFAALEFRSAHGDVERGRTFFAGILDSYPKKGDLWSQLLDLELAHAVAAIDKGEKADVQAIRDLFERRTKAKGLKPVPAQKWFERWADWETRSDAKGREKVMAKAKAWVLAYKAKQASKSKGAEEDVEME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWA3</accession>
    <name>A0ABR3YWA3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_004630</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000135">
        <property type="protein sequence ID" value="KAL1892274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048401">
        <property type="entry name" value="SLS1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048400">
        <property type="entry name" value="SLS1_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20778">
        <property type="entry name" value="SLS1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20776">
        <property type="entry name" value="SLS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SLS1 N-terminal" evidence="2">
        <location>
            <begin position="469"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="domain" description="SLS1 C-terminal" evidence="3">
        <location>
            <begin position="759"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="337"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1145" mass="127141" checksum="726D8CA5F2B0670A" modified="2025-10-08" version="1">MYVALTKPARQACLQCFGSRQTLYSVSRQARNFQALRLLRQEDKPGNPASHDPPKSSDTSAALDHDRIHASSPAAPDTKGLSSQQPPASSEENFKSFENIFSDISRQKSLKATAQNAETWAIEDFGFGSGEDVFGKSQRRNPSSHKKGSKGQGGHSSRDKPRSYDNKSNTRWTETRYNSRARNTTEAANRDELVSTMPQGRAIPENETEHQTSSQQNRNEWLDDDALVNVHAGREGHYPYSHSGRSRDSRYERDYGPGEFQLSPRQFRPRELKEKLKPRRRKPQEDEVLEKMSTEGLMFDMDGAMLEEALNTDKDTEKENDEAIAETEGQTGKVTDITEPLETTEATEAQTTEIQPPPSQNAPNSTHLPAIVPSNPADPTDPIKALESIPRQIQIENATTKNKRFRTRTQRVQISSEALDKPILGQPGQAIIMRTSRLPKNLDYETQVFESDSLDAGEIEAIARDRVVPTDQELVANIDELRPSSNIIQYEEFLRLQAMLDSSLTAENLQSYLDHYNTPRVLNPGTDFRDPEDIDYDWISGPVTWIPKALIKTEDFKRKNILILNLMLREWKLKIQEEEFGRGSMTVKIASQAVGLLLSPQTNMLSLLKKRYLGLGEDIRVNPLDNTFVVNASHALSLTLLRKINELASRMRGGSIPLALFDNRRLSDAEVRELAGITTAWIHQSPEGEKNPTVEVGWIEDVMPMPTIESIKHVVTRLMHVALMPAVESTALAIILPFGTATSEYAMLVQDHSNPKKRNWKNRMGEWMRLTTPAIEKPKTTEPESVDTIDTKKATQSAKTTVSKLALPVELQNALKWPLSTSEPRATSAPSAWSPITTRTSAVFGHMLHVKPTTATTSCVPCPAGPPTLSTSFLVPTIPHISCLARIPIDPATLPTESHTLVLHFVASPQSLPTAISASVAPKLELHISVPESASSITWLNSAKRLVYVRAAHRTQVLLPAADVDVQITQQRVQTLATDALVNNANLQTFIDESILDLVEGTLRTPPAVNLSVPLGDLETGSEVEAMSPELQFLFTGLEMRESFTAPFHGHRLAHSSIEAGYHGGQRAEFSLEPVIPTTTTSPNSLRINVSEPTNTLEDEIALAGSPDASTTDPSHAEDNYLCSVYAIATGHYFPWHQKLERFRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWB4</accession>
    <name>A0ABR3YWB4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphorylated carbohydrates phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_004675</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000138">
        <property type="protein sequence ID" value="KAL1892125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044999">
        <property type="entry name" value="CbbY-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42896:SF2">
        <property type="entry name" value="CBBY-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42896">
        <property type="entry name" value="XYLULOSE-1,5-BISPHOSPHATE (XUBP) PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1892125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="272" mass="29254" checksum="F2A05AD8EF6542E1" modified="2025-10-08" version="1">MPAPNPNPDPDPDPDPSSGLSFPANLSLFQISTILFDCDNTLVLSEEIAFEACADLINSICAEHNVALPAPFTGETLFTEFVGQNFRGMLNSLKTRYGLSITDSQMEDYVKREEGAVIAKIETSLKPCVGVDQQLALLAAAGEKELSVVSSSAKRRVLASIKKVGQNKYFPDEKVFSAATSLPKPTSKPDPAVYLFALETLGKTAGECVAVEDSKTGTTSANRAGIRVIGYTGPYPSEEKEKMAKVLTEAGANVVMDHWDQFPDMLAEIEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX17</accession>
    <name>A0ABR3YX17_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytosolic factor, phosphatidylinositol/phosphatidylcholine transfer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SEC14</name>
        <name evidence="3" type="ORF">Cpir12675_004335</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000120">
        <property type="protein sequence ID" value="KAL1892926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.20">
        <property type="entry name" value="N-terminal domain of phosphatidylinositol transfer protein sec14p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051026">
        <property type="entry name" value="PI/PC_transfer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657:SF1">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00180">
        <property type="entry name" value="CRETINALDHBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="107"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="304"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="327" mass="36785" checksum="885099214BABC308" modified="2025-10-08" version="1">MAAPAPVAAPLKLDPKYDDYDFPTVAAEPQSGHPGYLTPEQQAQVEQLRLLLEAEGFTSRLDALTLLRFLRARKFDVMLAKKMFVDCEEWRKNTNLDQILPTWDFAERAEVAKFYPQYYHKIDKDGRPVYIEELGQIDVASMYKVTTPDRMLTNLAVEYERVADPRLPACSRKSGHLLETCCTIMDLKGVSITRIPQVYNNVQKASELSQNYYPERLGRLYIINSPWGFSGIWNAVKRWLDPVTVEKIHILGSNYKEELVKQVPAENLPEKFGGTCKCEGGCSASDAGPWRDPQWARPAKWEKATAAATATQSAPAPTPAEGEKVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXP2</accession>
    <name>A0ABR3YXP2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_004444</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SH3YL1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000126">
        <property type="protein sequence ID" value="KAL1892676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11842">
        <property type="entry name" value="SH3_Ysc84p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11525">
        <property type="entry name" value="SYLF_SH3YL1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051702">
        <property type="entry name" value="SH3_domain_YSC84-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033643">
        <property type="entry name" value="SYLF_SH3YL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007461">
        <property type="entry name" value="Ysc84_actin-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629:SF2">
        <property type="entry name" value="SH3 DOMAIN-CONTAINING YSC84-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629">
        <property type="entry name" value="SH3YL1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07653">
        <property type="entry name" value="SH3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04366">
        <property type="entry name" value="Ysc84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01887">
        <property type="entry name" value="SPECTRNALPHA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="336"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="230"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="230"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="265"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1892676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="396" mass="41350" checksum="B3FDF500EA36F86C" modified="2025-10-08" version="1">MGLHNPLPSSLSSECKKCGKILSSFIDPRQSFGPDKIIPASILARAQGLAILTVIKAGFLGSARFGSGLVVARLPNGSWSAPSAIATAGAGFGGQIGFEITDFVFILNDSSAVRTFAQAGSLTLGGNVSIAAGPIGRNAEAAGAASLKGVSGIFAYSKTKGLFAGVSLEGSAIIERSDANEKLYGQRLTAMQLLSGAVAPPPQAAPLMNMLSSRIFAGVGGDSTMYNENPNYDYRNNSDNLSQSGGFNRPSRASTWQDPIYDRPNFSQPQQKQQTGAGANGGNLTRSSTVSSTRDASINPFPRTNTGSTLGSPAAAAVARKPAPPKPNLSAKSALMKKNEAVAMFSFEADQPGDLGFKKGDVITVLKKTDSDNDWWTGMIGNRHGIFPSNYVKMME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY18</accession>
    <name>A0ABR3YY18_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methylglyoxal reductase (NADPH-dependent) gre2</fullName>
            <ecNumber evidence="1">1.1.1.283</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">GRE2_2</name>
        <name evidence="1" type="ORF">Cpir12675_004395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.283" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000122">
        <property type="protein sequence ID" value="KAL1892811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043892">
        <property type="term" value="F:methylglyoxal reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1892811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="106" mass="11916" checksum="C56D00D232934193" modified="2025-10-08" version="1">MYNENSYSPLTLEDAMSNPHLAYSTGKAFAERAVWKFGEDNNPSVNTSDHRILAMVRGEMKHALEPTSKIGTFVVADHFTNKATAEAIRERLPELDEDLPPRDSHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY55</accession>
    <name>A0ABR3YY55_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000121">
        <property type="protein sequence ID" value="KAL1892841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="150"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="211" mass="22493" checksum="125E259E9C365D16" modified="2025-10-08" version="1">MSSANMHTQTASLSPRFAAYAASEPDSSYENKNTTLPQTNRPIDVHRRLMSPSSAPPPTNYSYPFTNIRRKPFQSSHARNGATHGKIQDQTATDASKAPGVEGYVASTVTIIPTSRLIVREQEPASTASLRGSSPMALEPGSIAEVPKASSSPGGVSSSSSRSSLTHLDEGKVITDPEEGKPATWSNASFLFPFLSADDATEDDTMVHLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ34</accession>
    <name>A0ABR3YZ34_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein frg1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_004246</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FRG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000116">
        <property type="protein sequence ID" value="KAL1893100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23339">
        <property type="entry name" value="beta-trefoil_FSCN_fungal_FRG1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008999">
        <property type="entry name" value="Actin-crosslinking"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010414">
        <property type="entry name" value="FRG1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12928">
        <property type="entry name" value="FRG1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12928:SF0">
        <property type="entry name" value="FSHD REGION GENE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06229">
        <property type="entry name" value="FRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50405">
        <property type="entry name" value="Actin-crosslinking proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="284" mass="31233" checksum="59694C74323522F3" modified="2025-10-08" version="1">MAKALVFKGDKKPKKRKRTADNDDKTNQALSAPTSVDNRDSYTGDHVDPDNDDRWVSADQPSDISGPLMVVMQSSAGDKPYALSCDATGKVFALPIENIVDGNVSSAEPHDVRQVWVANKAPGTENLRFKGAHGKFLSCDSHGLLSASAEAVSTLESFTIVPAKSPSSLAVFHIKTAQGNYIRIKSPSLSASSKSLEIRGDADSCDSESTVLRLRMQARFKPSIKLAKDERIKDKVSRSDLETAVGRKLEDNEVRRLKKARREGDYHEQLLMLKVKGKHDKYSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZH9</accession>
    <name>A0ABR3YZH9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MaoC-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004213</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000114">
        <property type="protein sequence ID" value="KAL1893235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13078:SF57">
        <property type="entry name" value="DEHYDRATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00640)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13078">
        <property type="entry name" value="PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MaoC-like" evidence="1">
        <location>
            <begin position="153"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="287" mass="31450" checksum="0AD652A7C45D9949" modified="2025-10-08" version="1">MLGPGTGFEYPPLPVSWNKRDLLLFANSIGFLGFKGDTSDVVDFYARQNAISIPGIPSFDPRRVLDGQRKMFFLKPIPHSSAGRRFETRTRVLGVYDKGIAGSVLETQEDLVDATTDVVYTRCIASIFYAGAASGDWGGPRGPPAEILPPPEGREPDCTVVQTSTRESGLLYRLNGDYNPLHATPEPGRAVGFKGDIMHGLFAWNTACHLILKNLGGSKPENIREFQARFSSPVMPGDHLQTKIWRTGMLVDGFEDIRFVTEVIGGKVCLTNGRALIKVVQKTAPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0A3</accession>
    <name>A0ABR3Z0A3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pru domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_004051</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000107">
        <property type="protein sequence ID" value="KAL1893621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.2020.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.70">
        <property type="entry name" value="Proteasomal ubiquitin receptor Rpn13/ADRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006773">
        <property type="entry name" value="Rpn13/ADRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044868">
        <property type="entry name" value="Rpn13/ADRM1_Pru"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038633">
        <property type="entry name" value="Rpn13/ADRM1_Pru_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038108">
        <property type="entry name" value="RPN13_DEUBAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12225">
        <property type="entry name" value="ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12225:SF0">
        <property type="entry name" value="PROTEASOMAL UBIQUITIN RECEPTOR ADRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04683">
        <property type="entry name" value="Rpn13_ADRM1_Pru"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51917">
        <property type="entry name" value="PRU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pru" evidence="7">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="150"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="150"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="399" mass="43595" checksum="707B3819F379AA9F" modified="2025-10-08" version="1">MSTEPLIVFRAGRCDIDTTVTPPRVTPKPDPGYLSLYNGEDADRFPELIHLCWRKRSSSSNDQPDLDLVMIPEDGNFLHYDSESPSAKTNGRIYVLKFRSSSQRYLFWLQSAPEHPTIHSRLSERDRKITDIVFNLLQGEEVDVDAELAALDEDDDEEEEEEEYEDEDEDEDEEMADQTTTARGTTGGAGADATGGDIRDEGEDAREGGADGGRAATETTANVDSVVRNLLASLEGSRQLSDSPHRLGPNDKPFPFLSHLLPTSVTVPIIDSGISEEKIDQLINLLPPTLVVVTANNGTNSAEISQDPTAEMLESAMASLSLADKRDLVKRVLRSPQFSQSLGSLTMAIRDGGLPTIAEALQIDVENNGYMRGSAMPLGNGKAVEAFVEGVRKTVSKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0C8</accession>
    <name>A0ABR3Z0C8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">aminodeoxychorismate synthase</fullName>
            <ecNumber evidence="4">2.6.1.85</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Para-aminobenzoate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">p-aminobenzoic acid synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Cpir12675_004111</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>chorismate + L-glutamine = 4-amino-4-deoxychorismate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:11672"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58406"/>
            <dbReference type="EC" id="2.6.1.85"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 4-aminobenzoate from chorismate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the anthranilate synthase component I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.85" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000109">
        <property type="protein sequence ID" value="KAL1893458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="entry name" value="Anthranilate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010117">
        <property type="entry name" value="PabB_fungal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01823">
        <property type="entry name" value="PabB-fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="AMINOBENZOATE/ANTHRANILATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236:SF18">
        <property type="entry name" value="AMINODEOXYCHORISMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="ADC synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="11">
        <location>
            <begin position="12"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Anthranilate synthase component I N-terminal" evidence="13">
        <location>
            <begin position="339"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate-utilising enzyme C-terminal" evidence="12">
        <location>
            <begin position="564"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="532"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="532"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1893458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="851" mass="93603" checksum="96393D5F3C929366" modified="2025-10-08" version="1">MAAPFCGRRVLFLDAYDSFTNNIVAMLKSIPGISVSVLKVDAPSVYVEPCTPEAIVRFRRELSRFDAVVCGPGPGSPDCPADVGLMRWLWDISDKESEPMIPVLGICLGFQSMSCHFGGSIRRLRGGLHGMVRPITHAGLPSSFSPLLEALEDSRSNIFSGVQAFNATLYHSLCVSLGQDDVPLAQWETQQWLPFAAAPELVPLAWHVEEREGGESERILMGVKHITLPLWGVQYHPESACTETENAKAIVNWLEAATQWNNKTRRIVNWSEKPEFAVDCLAPSHLEALTAFRISHKSEQPELQTSLHTRLTQRKLKLPPGIETPDLLEILQSASGDQIILDSSNHDVVLPAKTSDVRGAYSIVALDVGQAMHIEYRVGSSHAIVIQPSGSGETGKTRTSIPFKDRFENIWQLLAESLSQRKIPMPEGDGSSSPFVGGFLGYMTYEMGLENIHVKLANKDRGHHRPDLHFAWVVKSLIVNHREGCILVQHLKHEANVKDLDNDFWIETTIEKLQSSPTWRNAANKNYETANDAVANSPQPSSVNAIPSEESLTRPGVTVPSSINYCDGVSACQQYIAAGESYELCLTDQTTISLPLPASISPDSRRWHIFRSLRKQQPAPFGSYIRLGSATLISSSPERFLNTQPNGLCTMRPMKGTVRKSDFVQTIQQGEDLLHVPKEIAENLMIVDLVRHDLQTVCAAGDVTPTHLMKVEEYATVFTMVTVIEAQLPSHGEYNGLDTLAASFPPGSMTGAPKKRSCEILTALEQGQERSMYSGIVGYIDATGQADWSVTIRSLYSWDDENIVDENGQLTELWRIGAGGAVTTLSTPEGETAEMYLKLAGPLGALESLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0D1</accession>
    <name>A0ABR3Z0D1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_003819</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000097">
        <property type="protein sequence ID" value="KAL1894084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1894084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="163" mass="17957" checksum="21123C71B1BC2C3B" modified="2025-10-08" version="1">MNDIESTSLTGTIYLRNLTLPFLFALQSIPTAGFGNSSEFCQNVDPVLRSELEHLYVGLPNFHKTFFGDVPNLDTVSDAVFGRCTEGDNLFFEEGWIGWPAGAKESNVLAWFGDLIPKLEAFAGDRISVPAARQKLLVQLRTPLGGYTGKRNMDIGLVNNEIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0I0</accession>
    <name>A0ABR3Z0I0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Calcium permeable stress-gated cation channel 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Cpir12675_003963</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CSC1 (TC 1.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000103">
        <property type="protein sequence ID" value="KAL1893807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032880">
        <property type="entry name" value="CSC1/OSCA1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF5">
        <property type="entry name" value="RE44586P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13967">
        <property type="entry name" value="RSN1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="477"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="522"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="571"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="618"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="667"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="693"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="731"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="759"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like N-terminal transmembrane" evidence="11">
        <location>
            <begin position="56"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="12">
        <location>
            <begin position="252"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="10">
        <location>
            <begin position="475"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="853"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="298"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="865"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="912"/>
            <end position="923"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1893807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="932" mass="105280" checksum="3977E91978DDD3FF" modified="2025-10-08" version="1">MADNPQLATATVVAASEAAYDVLRLLAKRSVGDSEVQENCSGESIVNPGKGDLQFSFWVSVALGAPSFLAFCFLRTRWATLYSARKRRLDSLIGLPTLPNTFLGWIPALYRITDEQVLASAGLDAFVFLHFFKMSARLFSIMFFFALTVLLPINSTMFPSGDGVAKSKLQVQTHSLWDESSIDNNGTATQCTDLTHNDHPRVGGAKLQMFTGSYLAFTYFFTFLTLYMVNRHTRRILRIRQDYLGTQSTITDRTFRITGIPKELKDENRIRQLVEKLNIGNVVSVTLCRNWAPVDKLVAERSKELRELERALSVLHRKRQDILKAKQEQFARSTSFSVEQRDLLDVEDVALGRSLTAEGINLLPPSISEELYEIYRPKLRIWYGPFGLRTRLVDAIDHHEERLRQLDGRILTAREASYDPADLAFVTMDSTTACQMAIQALMDPRPGVLLTNTAPSPSDVVWRNTYASRNQRRLKSWMVTIIISILSVFWLFIVAAVATMLSLCTIKKVFPELGNAIESHTWLGAAVQSGFPVLIVTILNTLVPLLYEFLSYRQGMVSRDDIELSFVSKNFFFTFFNVFFVFTFAGSFSQFLPCLKEALQNITLASQLLAASTLKLSNFYICFIMLQTIGLVPFRLLEPGAVFLYVMSRVKAKSPRDFCEMRRAPQFSYGYYLPTALLVFILCLVYSILLKGYMVLMIGVIYFLASYYVYKYQLMYAMNQPQHATGGAWRVICFRIILGLCIFQVIMAGIIGLQGTWKVTPLLIPLYAITSWYWYYFHRRYVPLTKFIALRSIRDDLINESDGTVSNINNASLSDEDFEAARRAYFRRGTTLDEYRERDAKFINPSLKSKLSDPWIYDEPPSGEGSTTQSPGASSPSGGLAVLAPTPNLYSDNDSFRPPALESSPAFDGQNRGPSPSDSNISLGDTHIWREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3M1</accession>
    <name>A0ABR3Z3M1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_003400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000079">
        <property type="protein sequence ID" value="KAL1895128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022099">
        <property type="entry name" value="DUF3638"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022105">
        <property type="entry name" value="DUF3645"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046541">
        <property type="entry name" value="DUF6606"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051346">
        <property type="entry name" value="OTU_Deubiquitinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13367:SF34">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13367">
        <property type="entry name" value="UBIQUITIN THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12340">
        <property type="entry name" value="DUF3638"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12359">
        <property type="entry name" value="DUF3645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20255">
        <property type="entry name" value="DUF6606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="DUF6606" evidence="9">
        <location>
            <begin position="18"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3638" evidence="7">
        <location>
            <begin position="2054"/>
            <end position="2276"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3645" evidence="8">
        <location>
            <begin position="2401"/>
            <end position="2434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF20255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1895128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="3272" mass="370037" checksum="8BC54DB1994697A1" modified="2025-10-08" version="1">MASKEGSPSSVSSQDLFIIHHVFMPPSLPQADDHMGESEMGLVRSLQNAVRLFLHYCPNEHRDLISDISSGLEAFERIHSPNDSAVSVSEKEFMKELGLFSNANYLIPLFVEAQNAGIVIYRTNGATSIESFELSPLNTAVYQNNAPIRRKFPTSAATIDDSTMVKPEFQSVLAETVAKMSLQIASGTIPKVMKAGQLHQETRSPPSAHLVTGLLSRFFQSVGSTTSIVGVEKTTHDEVLWKDCLLPWRRSPIWLLVRVFIQMTLIRRAPGSGQFLYKAIMVFYMARVMRKACDTDIHSDFIYAMSSKVSKRLRKILELKLTNDENAIIEYCNLELEYASQVLYRRRSAAKAKGLQKVPAKLHEIGEPVCSVSLGALEEHINPKLEVQMDSISNFQPILAVNTSIELPDMNHVSNINNEFELLDLEAWILAIPSNFPDMIKKQSLWPLLRQLIMKYHEKSTLSYESDPISLSQAVLCTLELWVNLDKASMMAYERLEEYSPSFPIKRLGNLVLKSAGDMARLRRIEQYVQKRNNVAKHGFQDACSNFGHAKSLAVKLFDSDLKFGKLLSQIQAHDERKFQEKTVEFEQAKEKYKHYYDLHKILECEYVETVNRDGLLTKVHLSYCQSCQAYKTAKALRINICERALPSDQSRQKAVIVELLLPDWLNSWRDSTFILHRELFNALLPEYKAPYMKLPRYPALFSFASTCQERTITIGSQTKPHYSTHRKGASISNSTVQDVLAQNGLQWEYWQTSPTFQCCIPAEEMEYSIEKLKVFQFKMPRASQALDYFSFRVGQSAGPGPNEVISKQWQCPSHLSPDEFKALVTLPLGYKIQWPNILLQLASPVVDFNKEETITMVLQCIYQMGPMGDSSNKRISVSTVDDYMATKIISYLEATLSRFEENWDSSVALMTLTAIAARVLSLVWTPEVTKSGLMFLKRCREVALSWVQKLQQKLYNASQDEHLTGRLNHSILACAASFCIERKLLLPTLDDDEVLEQFVKVTILNYEMSGSLKERTTAQIVVQNSFNRISHEVLDSVVKAIKHNGRSKAIESALSFFWPEFTVIGEWTCQEMPFVHWVTCHAKSAGMKDKLYFVQLSLLTGQLLVDGKRLRRLPEDVLRHPDFINLFKSTVFEVAPSGLKGFVHQARCKFQGYQLHFGSNTGSGGSKQPHLKLCAISPTGAELYLLPAHTFESQFPDHLVQNHIHWYNKQDDVVEFRPLGKAWTHSRAHCRLYRSHDNKWTLRQNTCTNTSRAILPLSSLEFKTIAKVFSCFEEARHLEVSFQADTGMLNIQLPRFKHEFFMNSKTSDLVSKQYRGMKVAHKPDLGTLHGLKNKLVLCGLADPSRHKVLVLDGKEVVSQASDTGLTQVLIQPIEPFKIHAYDIDYTLGRLVDNGDFYSKLYICYMHALTSFCVPDELTGLTGTEQALEILNSAAVQSITSISEAMSEILVKISNLTPRREFYPQHLKEMQTINWRNGLGFMAQHGYFHVAVSKLVSSSKEFQTVFHEPSASVSLPITNQALIERDMWRSASMRVSEFGAESCLTISSNCIPEYNRASFHRRNRDDNLAAPCLEQTSKAMLALLEKKSLLSQDTNITSIVYTILTNEKHVSAPSLDSTQIFMGYDCQDLEDTLYCNKNLLPLFQMLSGHSGPKPNVFQMMMWIGAVVLAKTEIPDIIKICMEIWRQPQMALSIPEYRFDLSHGYSFSSSTINIVFSQYRKDPSECPKVENEDYETMSQEKLVDLVTGVQRKLSWDLCDEIQAQFPRFCPTLPEGRWKSWFDFIPVNTKLGELFRHWNQNLLLYNCIQSLEVTLKLQIPPVQPLLHSKSINMEIKTGNLVGRKVKGLILADDIFQLTAPEVSPLPSEVVITGLGSNIQKCQPGQAENKTRLDELVKGLKKLAETDHHRGYLNRLEESVASLRSQPPLLRKTRAAEEELCKQVDHHDYHGLLSKADDLRAFYEGETNKIFNSIASAYSSHRKTNRILVSDDLHQPRFTPFFFFKRLNGYELQRDWRSIISAYGIAITQVQRAGRVQSAILREDWVALKSELNNIGHLNWSPEDYPSSLLLEIDSGLIIREVQQNVASLMINPPSDQNCVTQLNMGEGKSSVIVPIASAALANKQRLMCVIVAKPQSKQMLETLLTKLGGLVNRRVFQMPYSRGLITTEAQAQLLLRLLRDCQNVGGVLLVQPEHLLSLKLAGIQAKLSQSPCADTLVVIQDFMNKRSCFLVDESDENFSVRFELIYTIGNQQPIENSPQRWFTIQEVLSLVAAHIGTVQEKFPQSVEISQDKAGSFPRVRILDADAMQYLIEKVAKDVCNKGIASFSIITQPASRRKLAEKYLLDVNISASDVTEVENTFSDGKYSDQIFSALLLLRGLFSMGVLAFGLMKKRWRVDYGLDASRTPKTYLAVPYRAKDSPSARAEFSHPDAVMILTSLSYYYGGLSNDELFQCFNILKLGNEPETIYALWTDKLIGIPDSFRSLSSINLKDRSQCIQMVFPHLKYSKSIIDYFLSNIVFLKEMREFPERVSASGWDLSETKNNPTTGFSGTNDSRDLLPLDIIQYDRESLKGTNALVLSYLLRPETGVHVMPQKMPHSTDSDAVILLKAVTQMTPPVRVILDVGAQILELDNEDVAKEWLYMVPEDARTQAAVFVNAKDELSVVNREGIIEPLQTSHFAAQLDVCLVFLDEAHTRGIDLKLPTNYRAAVTLGTGLTKDRLTQACMRMRKLGHGQSVIFCVPDDIRNKIAQQEEDPLLLKAVPTVSDILAWCIRQTWSFISDGIYLWANQGSRHRHNQEYWSETWSLDKNMSIATAQKFREPETQTLKERYHPSLTANDQFSKLGLPDHHPISRRVQEFGKHELAGSMLNEEQERELAPEIEQEREIQRTPPIEAKRHMWNIGVSDFIETGVLPKGPNFRRAFKMFAQTSANKFYPLAKIKCHIQATEDFCETVEISKETSCTTLLDSYLRNVQWILATTIHQGTSHASTLNCELLVISPFEAEIAVDMVKKSPGYVSLHLYSPRVNFGLPSLDNLDLLVISANAKHKYLLPMTKDVAPHLIRELNLFAGQIYMSSFDEYLAICNYLGLTTEPTREGEDIAIDGFINRDMQGRVGGGSLFFKSPVPFFQRVMSLRRGNARILHSHMGAVLSTRILTQRDFEKPDMANFASRESSQVSMAKSIANVAHSTTNGDSTTHDIAKYEIESEDIAVGSAPQASDNEKGTETVGFFDFGKTFVDGRQTGPIDLKYEDESDLSSGDQSLVASILEDMHLGTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3U7</accession>
    <name>A0ABR3Z3U7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycosyltransferase family 28 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_003317</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000076">
        <property type="protein sequence ID" value="KAL1895300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF5">
        <property type="entry name" value="UDP-GLUCOSE,STEROL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase family 28 N-terminal" evidence="3">
        <location>
            <begin position="280"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="Erythromycin biosynthesis protein CIII-like C-terminal" evidence="4">
        <location>
            <begin position="602"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="51"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="236"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="815"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="77"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="843"/>
            <end position="853"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1140" mass="124618" checksum="2E5DFC73B450AACD" modified="2025-10-08" version="1">MAFNRPSDAHMGFHAHDIQSTDGASLQTVIHDADENVAFPSFIPPRIEMTRPEAVRSASSRKNSESPRPGVLRRLSSAITPTRMRSQTQVEPVDAGKQQRQNQRNLYNRTRANTAGANNHLASQQPNRNCPGNEGDRSSMCTFDEDADMQHRQRILAANALDPASITKHRRRHRDDLSYFNIGQENCLSRCRFDQSDGRLSITLNDNSHGGGLARLLGISPSSRRLEEATTAAMSANNQGTSDAISLAGSSDPAATQVPKPPRLSEASTVTPLRVPRMNIVIMVIGSRGDVQPFLRIGQLLQKRHGHRVRIATHPDFRQITEDEYGLEHFSVGGDPAQLMAFMVKNPGMIPTLESVKAGEIGRKRASMEEMFEGFWRACVCATDDPKYAFNSKVMAAGDDMPFVADAIIANPPSYAHVHCAEALNIPLHIVFTFPYSPTQAFPHPMAAIKHSNVEPGAANLVSYPLVDMMVWQGLGDLVNDLRIKTLSLDGLSAFWAPAALSRLRLPYTYIWSPGLVPKPADWGSDVDIAGFVFATNGSNYQPEPALAEFLAASEEPPIYIGFGSIVVDDPTAFTNMIFEAVRKAGVRALVSKGWGKLGGDDVPENIYMLGNIPHDWLFPKVRAAVIHGGAGTTAIALKCALPTMVVPFFGDQNFWGSMIAKSGVGPQVIPYKELTADKFADGIRYLLTDEAKAAVQKLANSIAQDGDGAENTVNLFHSHLDLKKDKMHCSILDGHTAVWATRWGKTRFSPLAAAILVAEKKLTWKQMHLIQHHEFRDFYGPGEPITGLISTIAEGVCKIFVSVVGVPVNLAKTARKNHKSQNRNQAKGDSDATANAEDPSPVSHSHSLQRTPAHTAAAIQENLKNEPIPEDPFLPPGVPHPKDEYLRAVASGVGRSALVIFLMPLVVGNAIAQGFHNAPLLYGDTTVRPQLRVTGIKSGLRATQTEIFYGVYDAFTGVVTQPYHGAKTGGTRGFVRGVGMGLSGLVIKNIAAATSIVYAAKGVVRQAQRHRQPKAWVRRARIIQSVRELEQLSPKERDQIESQVLKDWEVMFELFNTINDEQREPGLKGFVTRKRAAHDIGNLFDSADNAKQALDALKRGESLDEVFRAAGNKSMATCWKTSHFAKKKAEKDATPPTNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z412</accession>
    <name>A0ABR3Z412_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UDENN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003233</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AVL9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000073">
        <property type="protein sequence ID" value="KAL1895373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018307">
        <property type="entry name" value="ABL9/DENND6_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051731">
        <property type="entry name" value="DENND11/AVL9_GEFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037516">
        <property type="entry name" value="Tripartite_DENN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31017:SF1">
        <property type="entry name" value="LATE SECRETORY PATHWAY PROTEIN AVL9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31017">
        <property type="entry name" value="LATE SECRETORY PATHWAY PROTEIN AVL9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09794">
        <property type="entry name" value="Avl9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50211">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDENN" evidence="3">
        <location>
            <begin position="114"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="618"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="680"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="759"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="618"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="634"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="693"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="706"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="765"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="775"/>
            <end position="788"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1895373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="802" mass="88214" checksum="AF81744B3063A45C" modified="2025-10-08" version="1">MSTEEPIDPWKEPQAQTEEVAPTPEDIKQTLPSPPSPASASPPRSPLPNPNPASITTPAADTVSTPPVSSPPAAASTDPAPIPAITPVLKIAPGVLSQIEPSTPSTPSQAGFIPLVSIVDFHHARGPEVEYWFGADEGQDPAAEYGWSLLPFMALSDGAHASSEDFSYFTLLRPQSPMNGPAISLFGIACTRQLDSTMLKVRPPDVTRSTVQKAVVVITDSPQHFGMLRERLSIVTQAWFAQREFTDVEILHHFQESLADDKRRGMMSPNVDGGDQYLGLSLREFVHEFKWQTLVLLKCCLLQPKMLFFGTRCDRLCMLQFCLISLIPRLIRSMQDCADPDLNAYEKTLAKSVSFRSSDRASTLAFMGLPLQIFGKGALFGPYTPLQQLDVLADVGTKSYIVGSTNSLLLQQRDRYSDILINLDENTINITSSSLRSALSLTAADRRWIDFLTQAVNDTWDDANPANPTNLQYMGSEAFIRMQFEEYIIAMLSSVRYHLFIQKDPSKRLAHIDGDPALDFGLDWIEAWTRTENHRMWRTHTDDAIFDVVEPRHPCAGGLTIDDVQRRISEQVKELHLDDKLAQGKEVIGRNWAAGKDRASAVVNKFWTDMEAFRELQRKKAEEEKQKAEARTQSQGPEQAPNSAKSNSQSTITDEKAPVMTVGERASSYMSSWTSWAGEKRKTGGGWGFGRKTSPNTPTNSDSPPLGNTATSTDSGYDDKTRDVSSSHSAPAGRYRSLHTSNLSGSSFELAADIHSDDDYDDSRVQQIAQTTSRAGSASTDTATVTASPETFQTAGALDTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4Q1</accession>
    <name>A0ABR3Z4Q1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NDT80 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_003222</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000072">
        <property type="protein sequence ID" value="KAL1895533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1390">
        <property type="entry name" value="NDT80 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052605">
        <property type="entry name" value="Fungal_trans_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024061">
        <property type="entry name" value="NDT80_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037141">
        <property type="entry name" value="NDT80_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35144">
        <property type="entry name" value="MEIOSIS-SPECIFIC TRANSCRIPTION FACTOR NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35144:SF4">
        <property type="entry name" value="TRANSCRIPTION FACTOR VIB-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05224">
        <property type="entry name" value="NDT80_PhoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51517">
        <property type="entry name" value="NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NDT80" evidence="4">
        <location>
            <begin position="120"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="NDT80" evidence="2">
        <location>
            <begin position="120"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="394"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="524"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="537"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="562"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="593"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="643"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="658" mass="70947" checksum="0275194E482E98F0" modified="2025-10-08" version="1">MTAATASYPASMADLKSEPSHSAMWPSFSQPMHMTSRYAPTIDQALSRPRHSVDLPPPYPTFHSQQSSSASAGQGTSSTSSGPPRPYHEDDYDRNQPPVPQQTYPSLKRPYAATEPAPYQEIIQDLREDTKLNVGHDQKLLSFKRSHDKHTIVDQHGRMQQLEMNAQLHGMFFLSEMPATASDGTALQAELTCYRRNLFQISGSLICPRGQLNVVTESGETVPITNMEVTISAIESVDGNFVRLIVIPWKTPPPNAPDVAQTSDQEPPTLPLIPFQDEGSEADGEYAVYPIGWRRLQFRIATANNGRRKELQQHFVLHLKVIATLANGNKTPVAESVTSPIVVRGRSPRNFQARKEIPLLGSSAGSRGQALVENGIGIVAGPLTMKPDTKRGLDIKPPRSNFTFSAPKPPSAPVAMRSNSYSSPWTANSMSHMPPTPTTYPPTTVSGDSYPKVTLPGTSGFHSDSQDIALQTPVSSVSSIPPVQLSLASQEQGAPIRTQYAYAPSTTGASQLSAAAVVDSSLSVPRYVDGNPRPSKSPRNSYPSGSITTPSEHASEYRYGPSYNNITLNTNTGDFNSGDSSTPNSAPPRDYYPPASTWTSSSESSAPSSAYTSDSRSYSFDAYKTGSATVPPPPPAKGPVPSSTAAPLYSSSNYSWNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z523</accession>
    <name>A0ABR3Z523_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">C-5 sterol desaturase</fullName>
            <ecNumber evidence="8">1.14.19.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ERG3</name>
        <name evidence="8" type="ORF">Cpir12675_003124</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.20" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000069">
        <property type="protein sequence ID" value="KAL1895733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050046">
        <property type="term" value="F:delta7-sterol 5(6)-desaturase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050307">
        <property type="entry name" value="Sterol_Desaturase_Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11863">
        <property type="entry name" value="STEROL DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="7">
        <location>
            <begin position="167"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="343" mass="40409" checksum="84EB52496EAE7D65" modified="2025-10-08" version="1">MDIILQVIDTYVADHIYAWAVPARITSHGGVPGSHNSSASFSNWKYEPATSYLYMEPSPSAYLSEWNREHTLRQAITLFFITWIFGVLLYFIFATLSYCFIFDKRTFDHPRFLKNQMSLEIKQANQSLPLMAVLTIPFFVCEVKGWGKLYDTLDQAPAWWYNWLQFPLFLVFTDFWIYWIHRGLHHPRIYKHLHKPHHKWIMPTPFASHAFHPVDGWAQSLPYHIFPFVFPLQKVAYVILFAFVNFWTIMIHDGEYLTDNPVVNGAACHSLHHSKFEVNYGQFFTFLDRLGGTYRRPEAYMFEKELKMSKKTFQKETQEVDDVVKEVEGGDDRSYGAEDKKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5L7</accession>
    <name>A0ABR3Z5L7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Nuclear cap-binding protein subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">20 kDa nuclear cap-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CBC2</name>
        <name evidence="11" type="ORF">Cpir12675_003185</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the RRM NCBP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000071">
        <property type="protein sequence ID" value="KAL1895547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12240">
        <property type="entry name" value="RRM_NCBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027157">
        <property type="entry name" value="NCBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034148">
        <property type="entry name" value="NCBP2_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18847">
        <property type="entry name" value="20 KD NUCLEAR CAP BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18847:SF0">
        <property type="entry name" value="NUCLEAR CAP-BINDING PROTEIN SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="51"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="128"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1895547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="188" mass="21904" checksum="4011D77CCBB32346" modified="2025-10-08" version="1">MAPSRNSITVDRLDQPSAYYISKSKKRHHKGDQQTPEPRAEPTEDPLTNSTTLYVGNLSFYTTEEQVYELFSKCGEIKRIIMGLDRFTKTPCGFCFVEYYTHQDALDCMKYIGGTKLDERIIRSDLDPGFEEGRQFGRGRSGGQVRDEYRDDFDEGRGGLGRSLQSERMRDHERRGREPEEDYERYSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6L3</accession>
    <name>A0ABR3Z6L3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RecQ mediated genome instability protein 1 OB-fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003034</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000066">
        <property type="protein sequence ID" value="KAL1895812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.770">
        <property type="entry name" value="RecQ-mediated genome instability protein Rmi1, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042470">
        <property type="entry name" value="RMI1_N_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013894">
        <property type="entry name" value="RMI1_OB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08585">
        <property type="entry name" value="RMI1_N_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecQ mediated genome instability protein 1 OB-fold" evidence="2">
        <location>
            <begin position="86"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="254" mass="27241" checksum="86AD41C9FA8C46E8" modified="2025-10-08" version="1">MDAIATQLINALKTSRFPVPTVSWVRSFLSSQQLPATSMTPTQLKPLIEATRTRILASDISAAGFLDPAFCNLFPLHTSFSPEVADAKIPKEVFVQLMDIEDLTRSRWDQVEELEAIERGESKKGREIVRISTEGGETTSDDSGNRDGAPSLGGSAAAAAAMKSKGNATHRVVLQDMKGFRVFAVELSRIEALGVGITTIGAKLLISAGASISRGMILLEPSNCAVLGGGIASWQKKWLNEKKTRLKVAVSGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6W5</accession>
    <name>A0ABR3Z6W5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002996</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000065">
        <property type="protein sequence ID" value="KAL1895957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054289">
        <property type="entry name" value="DUF7025"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF3">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22942">
        <property type="entry name" value="DUF7025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="340"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="649"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="696"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="710"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="737"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="770"/>
            <end position="780"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="780" mass="88147" checksum="C4C535A60FA2FEB8" modified="2025-10-08" version="1">MAVSPPPYKSDYERLDDLDKQPRLRHRPAGNSQANEDNLRIDTYCVDFDGETFGAVQRMFYIEPYSGERQITQLKCFPARFLRYHQGIISNLVARGSSFQSFTRKKSVCVKGWTLTHSPLGKRYRAAGADDDPTPLKSQYVDSKVILACSEAGHMTPSWRPDFVQNVTYFDNVQGDQCRQQLDIIWWTDRRRVQQVGGVLDYVSLISSKPGGYAVKDIKTCSFLQYCLQFRAALLDHDSWKRISAVPINMPSESDVLVLLPRSIFGYVLDDHCFAVLDTTTLHTPKPRKQEQTLEKLIIPHSFKDAISTLIDAHFANRQPSEPWPWTKRDTRNSGPKDEQRVAILLHGPSGVGKTATAEVFAHKHERPLFRVSCGGLDCMSEAMEADLQEIFRLASLWDCILVLEEIENLLYTRMHSNFVHMLERFDGVVFITTDNIDAIQPALRNRVNLSLSYLDLHYKATRDIFKANITRDQASPISWDSRSIPVQLGASFRKPECSQGWSSWLVKNTVKIAESFARNDYRARNGVLPRLSSEHLLMAIEMIRKADDRVLPVEKKEYYSEVGRAKRVRVDPFLSPRNSEDPYLRRAHGYHLSTAPGENEYSGRSTYHDACSTSYDSNAYAYPQTSYNNEQYGGGPAPYPNPPYEAVGSSAYQSHQPPPTSGWPMAKSPVPECPKGMFDSKPPYVPQPWIPQACSSLMGSSGPPRPFDQTGSLGQTDTQHSSACPWQSNTRTQRQNAESSSANRSRSIRLNGSERPRGYAKASVMEVLDSSTEESYISD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6X1</accession>
    <name>A0ABR3Z6X1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_002820</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000059">
        <property type="protein sequence ID" value="KAL1896416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF64">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11760)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="259"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="431"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="458"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="502"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="525"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="135"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="34"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1896416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="583" mass="63285" checksum="6D5E2B979718D5FD" modified="2025-10-08" version="1">MSTNQSPHTHGQPFPAPSPPPSASAPPNTPIPQPINSSFSDIPKSPNSPVRESDSNTPSDFHKETKWTPEAHTAKIHTETPDTHSIASENLRRHFTHASVAGPDAVAVVLEESISNTEVPDSVYDRFTSRQKIMIVALLAFCSFLASISSTSVLVASPEVASEFDTTGTIISLSNAMYMLSMGICPAIWGPLNTVYGRRPIVLICAASFFACSIGTALAPNLGAFFFFRIATAFGGTAFIIVGSACIGDIYRPTDRATALGWLLSGNLIGPALGPFMGGIIVTYTSWRVIFWLQSALAAIVLAGSIFLMPETIPHRKIDDLAGYPASRKARALMTMINPIRVIELYRYPNLFLNGIAAASMIWNMYSLLTPIRYVLNPRFNLDSPMMGGLFYLAPGCGYLTGSFIGGRYADYTVRKWVEKRGGERIPEDRLRSAIPFMGIAMPVCILVYGWSVEKNVGGIPLALITLYLQGVAQLFCFPSVNTYCLDVNQARSAEIIAGNYLFRYLFAAVASAIVLPAIDALGVGWYTTINVGFLICSAGGLLACVKWGKGWRDAIDDGRRKKRWEARMEAGKATCDKTKSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z731</accession>
    <name>A0ABR3Z731_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DNA replication licensing factor MCM3</fullName>
            <ecNumber evidence="11">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">MCM3</name>
        <name evidence="14" type="ORF">Cpir12675_002788</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="11"/>
    <dbReference type="EMBL" id="JAWDJO010000058">
        <property type="protein sequence ID" value="KAL1896451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17754">
        <property type="entry name" value="MCM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008046">
        <property type="entry name" value="Mcm3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056575">
        <property type="entry name" value="WH_MCM3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF46">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23191">
        <property type="entry name" value="WHD_MCM3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01659">
        <property type="entry name" value="MCMPROTEIN3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 11" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 11 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 11 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="13">
        <location>
            <begin position="316"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="687"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="714"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="740"/>
            <end position="765"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1896451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="882" mass="97238" checksum="5F902755B3ABCAAA" modified="2025-10-08" version="1">MDSYMLQDAAIRDRIRQAEEFLDPGVTIITGTTKEQNEKDRASSSPKYSYKGEIGLMLQKSQRRLVVSIDRLRDHSPQFADGVLEQPFDYSLAFNHALKAIVKSINGVQNDDEAEYYCAWSGSFGLYTCNPRTLSSRHLNRMISMEGIVTKCSLIRPKVIKSVHYNEAKNNFLFREYQDQTMTNGPTTSSVYPREDEDGNQLVTEYGYSVYRDHQTISIQEMPERAPAGQLPRSIDVILDDDLVDKVKPGDRIQLVGIYRTLGNRNTNHNNAIFKTLVLANNVVLLSSKSIGGVATSTITDHDIREINKLSKRSNLLDLLSQSLAPSIYGHDYIKKAILLMLLGGVEKNLENGTHLRGDINILMVGDPSTAKSQILRFVLNTAPLAIATTGRGSSGVGLTAAVTSDKETGERRLEAGAMVMADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHTSLNARCSVVAAANPIFGQYDTHKDPHKNIALPDSLLSRFDLLFVVTDDIEDTRDRRVSEHVLRMHRYRAPGTEEGAPVREVASQSLGVGVEKETSKNVRTEIYEKYDPMLHTGVRIRRNNQKPEVVSIPFMKKYIQYARARKPFLTPEASTIIGDIYVGLRNDEMEGNQRRTSPLTVRTLETLIRLSTAHAKARLSAKIEEQDAVAAEAILRFALFKEVLNDAPKKKRRTNIPVVESSSDEGSGDDNPVPLQASVSRTSTGTAASARQTRSAARGASTIPGTHSFPVSQPQPPTLSSFNPGMNFSEADATSQASFASSIPLSQLQSQWQSQPQSEVSEGLAISAASLTISQPEISPARMETFRRSMGRLLMGPLFSSDDTAQVTDIVTSVNEMLTSNEGGPFDKPEAIQALEKLDALGSIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z740</accession>
    <name>A0ABR3Z740_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_003261</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000074">
        <property type="protein sequence ID" value="KAL1895354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010573">
        <property type="entry name" value="MFS_Str1/Tri12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF33">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06609">
        <property type="entry name" value="TRI12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="184" mass="19592" checksum="D4CBCD5BC06A2504" modified="2025-10-08" version="1">MPRINLAATAGRSAGGPLGGWLADAAAGRNARRASVEAGGEGEISEDGKPKAELDLIGALLLSLSILAFMFPVQMGGSLFPWNSPWILALFAASLVLLGLFITCEAHWTSSPLLPRMLLRNREATASFLIMFLQTSAQVSLMVSIPIFFQVVHKSSSSEAGWHLFPAVLGNTLGSILSDMIIQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7U4</accession>
    <name>A0ABR3Z7U4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RmlD-like substrate binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002754</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000056">
        <property type="protein sequence ID" value="KAL1896658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05254">
        <property type="entry name" value="dTDP_HR_like_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005913">
        <property type="entry name" value="dTDP_dehydrorham_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491">
        <property type="entry name" value="DTDP-4-DEHYDRORHAMNOSE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491:SF4">
        <property type="entry name" value="METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RmlD-like substrate binding" evidence="1">
        <location>
            <begin position="7"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="317" mass="34507" checksum="31A57FBA5184903C" modified="2025-10-08" version="1">MTTDIALITGATGLLGREVFKAFTDGGFETKGLGYSRADGVSILKADLQNPDQITAVLEKVQPKVVVHCAAQRFPDKVDKDPEAARALNVSATASLAAQCAAQGALLIYLSTDYVFPGIQGEAPYEADAVPRPPNLYGQTKRDGEVALLEEYAKSSTDSRAVVLRVPVLYGHAETPAESAVNVLMDTLWKAQQGNKVKMDAWSVRYPTNTEDVARVIKDIAIKYLGTPATEKLPSILQFSSEDRTTKYGICLRFAEIMGMPSDGIEPQTDGGDPNTAVQRPYDCHLSTQALKSLGIRVNTMDFNAWWCRELRAFRGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8S0</accession>
    <name>A0ABR3Z8S0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_002764</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000057">
        <property type="protein sequence ID" value="KAL1896475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05474">
        <property type="entry name" value="SAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033876">
        <property type="entry name" value="SAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF65">
        <property type="entry name" value="ASPARTIC-TYPE ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046540146" description="Peptidase A1 domain-containing protein" evidence="8">
        <location>
            <begin position="20"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="9">
        <location>
            <begin position="66"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="447"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="451"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1896475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="492" mass="52295" checksum="4E64E018E61BB32D" modified="2025-10-08" version="1">MRASISFVLLSAILPPCLAAAARRDEPKVLQWQTQRRSPLASSRRLRGRATSGTLDASWLNSGSAYFTNISIGTPAQSFNVQIDTGSSDLWVPDAASGACQDGNCQYGAFDLSSSSTYEETDVPFNITYGDNTFASGLYFNDTVTISGQSLPGLVMGLGSDTDNFYGVMGIGFPRDEASPVLYHNLPAALVSDDIIKSSAYSIWLDDPDDNKGSLLFGGVDTAKYSGDFKRVDIVPDPSLGYVYLQVNLTRVVASSSSGNDTLTSTGFPLTVILDSGSSLISLQSDLVKEIWTEVGAINGSQTVTLVNGVTTIPSIYPLLPCSRATNNGSFSFRFGGADGPEISVPMSELVLSLTKTDTEAKFSSGDYKDQDACYLGIFETDDVNILGDTFLRSAFVTYDLSNKQIALAQAVWGASDSSITTFTKLNETIPGSSLVASQAETESISSKEPSYSAKSGFQSSSSGTKSSASRDSSLSLFTLAFIFAFTLSLEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8Z9</accession>
    <name>A0ABR3Z8Z9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000054">
        <property type="protein sequence ID" value="KAL1896722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37852:SF1">
        <property type="entry name" value="HIG1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37852">
        <property type="entry name" value="YALI0B21208P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="212" mass="23160" checksum="46A13C88BDBB3508" modified="2025-10-08" version="1">MARDSSTTPNLDSDPGRQLHSQAFPALAVNDRPRLGIPTSVRLLAAGSSSFVAGALLGMTHGGRMAQLRFRAEHAHKMPSTMTGWYLYHKSKNYHAAQGAIVEGARMGCRLGVWTTAVFALEQTVDRYRGRRDLVSTVLASLTVAGLFSMWNRFNMPTFTRTARYGLAFGLAYGGLQDAVFAAQGNASDLSYVELTQKLVRRAKTMLEGDTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9K2</accession>
    <name>A0ABR3Z9K2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">54S ribosomal protein L11 mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002565</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000051">
        <property type="protein sequence ID" value="KAL1896984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047865">
        <property type="entry name" value="Ribosomal_uL10_bac_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11560">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="312"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="334" mass="35717" checksum="FF16EED2C105E26D" modified="2025-10-08" version="1">MPRAARQLARGVGAVPTVSLASSFSPSAALVRTLSTSPSALYSAAPRSFRLPENYVPPTQPPSARPSETRKSQIIRTYTSLLRSTPIILFFQHNNLTAVEWAAVRRELSVALKTVGPVDVGGADGKEIDISSNVKLQVLRGRMFNVAMRIVEFHDPKGVSEGETYNHDLSRAAYRAIKSAEEARDPNSIHATMEPLLSGPIAALCLPAVSPEYLAAALSVLAPGPASPAPKRRARPSYYEPETQNALAKLMLVGGRIEGKPFDRQGVAWVGGIKGGLAGLRAQVVHLLQSAGLGLSTTLEGAGKALYVSLESHRQNLEPKKEETAGDGQEENKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAP6</accession>
    <name>A0ABR3ZAP6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000041">
        <property type="protein sequence ID" value="KAL1897736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046893490" evidence="1">
        <location>
            <begin position="19"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="151" mass="16008" checksum="A4AE3864B137B23A" modified="2025-10-08" version="1">MKFSLASTILAAVAAVSAAPSKQLDDRDTPTQLTLRFRAAAAQYDLSFPADGEFHETGNTELNVNLIDTPGINAMTQCEFKTNGAMALASTFDNEGNPQVAVGPPQPIVAVKCWGTCVPIYSDCFINGVSQGACCTGYCAANKCRPFQVTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB03</accession>
    <name>A0ABR3ZB03_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RGS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002711</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000055">
        <property type="protein sequence ID" value="KAL1896689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07440">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00315">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RGS" evidence="2">
        <location>
            <begin position="11"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="244" mass="27250" checksum="101BC72699BD6FA3" modified="2025-10-08" version="1">MSLPRPDLQDVLKNRAPPPFTLGAFMAYLSQNHCLETLEFSLDAEQYRLAYTRSLERSAGQFSPRDVDHLTKLWEKLLHVYLMPYATREINIPAYVKEPVINIDYFAAIPHPDVLADIVRVVHELMTDSVLGPWVESILSSPVALEGSRRRSGLSSPPQSQYKYMHGRSNSSSLERETRRKSPMGEPVTPPTTPSIFEWTLAGSPPSKSCNSGGGGSWRKMSAKLGLAKKKKSVASEMPLPGYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB69</accession>
    <name>A0ABR3ZB69_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002389</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000046">
        <property type="protein sequence ID" value="KAL1897285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050126">
        <property type="entry name" value="Ap4A_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42850">
        <property type="entry name" value="METALLOPHOSPHOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42850:SF4">
        <property type="entry name" value="ZINC-DEPENDENT ENDOPOLYPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="476" mass="51263" checksum="E1CBA1BA63B39C89" modified="2025-10-08" version="1">MPLPPCLPVVNRKFRRSLAICTVFTLCTMLYTTRDLFNGQVTSDIFSPEDIGSLSTFASPPDDQQAFRPDWDPNEGKHRPDDDPEVNLGATTTGSTPMLYNSAVRPSFFGAGKATLLREIDHVLIPTVDNRRRLLIIGDVHGMKKPLSQLLVKANYQPETDHLVFLGNAIGSGAASREVLDFAMAHKATLLRADVEDRVVLSSASYYDAVANELGYAVSNTSALHAPGSKAGPDPAGDHNIRKQDHFLHGDHAHRALAASLSAAQLAKLAAAPAILRVPMPGNAPPLALVHGGLVPGVPLAEQDANVVMTLRGIQYPREIARLDDAVRIVNKRIADLAAQDLPHVFGRRTLEKMVRAEFAKISRPTDRDMVVPTDFADHPESDTTDPWAAVWNARADKAMAAAASGSISSSSGAAGTDERYMVVYGHGTGSGLEDGRWTVSLDMGCVDGGRLALLAVSMTPHGMKREMKTVSCGWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCL2</accession>
    <name>A0ABR3ZCL2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002033</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000036">
        <property type="protein sequence ID" value="KAL1898085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="457"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="519" mass="57551" checksum="A3023443C2D0E85B" modified="2025-10-08" version="1">MSAKSQITPKNITTSNAKDSRGSLGLVTPESTPEVEYGRIKADQERMAAAMRQLLEAASASPANTSNKEAIRAVSDANAQSEDVKTEIERILRCLDSSYTDILGISPNFPEKKVVAAWRHLGCLLHPRFLKHPGADAAFKKLQTAARKLGLSDLDIDEVYYWNGEKRFDTSEPSTRANKNAVSVPSQRVADIYQDSMPVLHRLDQDSSHSALLGQLGRLDAKISGVNQAKKIARATAITVSETVKAGLAAEDASRIVGAATSAARAFQSSIEYPWTTAQAADGSLIVGVRKQGRFGTQVCIETQENDGRMIRRLESASEVGLLQVQRYWKMNSFKDLAQGQSQWSHKDRSDFDQLLWITKSQTKLKNTAANNKSPSADCCVKFRNKGIQILSVTSLTKVLGPSSARAEIEKVCKRDNVLPPWKAGWVSQYSDPSKIEQDPAHRRALRDAQANLSAHNHLDQRKRSLHGDAEKESRAVKQLEDRVRKLENEMKDMKDMAVAMNQNMETLMRMFEDVMKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDB1</accession>
    <name>A0ABR3ZDB1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000040">
        <property type="protein sequence ID" value="KAL1897793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="420" mass="47809" checksum="C02104502230E902" modified="2025-10-08" version="1">MPDFTHWAELPAPPENTTITVDRIRQALGDAAAPPFLARLIGFDTERKLNAVRYSVQRSQDALTDRTLTDSELAALAQYASQEGDSQITDHAIVISTALGLTLWGRKAMRFPLWRAPDMSMFNTFPSAGLPWLRGRRAQRAWHVARFATYYIGTSVTLGSFLGVLSTRAALTHKAIDPRLRDFLRESILDPQNQEILLILQKERNVEPIQFRRQDDPWVIRAREIRRNRFYEEAEKSMTPAQREATEKRRHQAEKAEEEWRQRVGQAQRKEALPVNSPESVWAQRRSGVMPTSQLNQQAPQDADDDDPFALDGDDDQDASPVPTRIRRQEQQEREEREQRQQYEHQSWAQAQGQDGRANGQGQGSAWDRLREQAAQDSAAEAPGTGPAGRGGWNKNKHQDFDSLLKADRQGGQQANSKWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDI4</accession>
    <name>A0ABR3ZDI4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002059</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000036">
        <property type="protein sequence ID" value="KAL1898110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="102"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="370"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="321"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="124"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="220"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="389"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="427"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="446"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="535" mass="60055" checksum="26B4380349ACBC2A" modified="2025-10-08" version="1">MCYSTITFYCGCARKIRMDCRSPRFGCFSSLANMTGAKTDCERHRSASASSTTCGRAACEEVYPDAPRRSRDRRHHNSAPVTSVSVHTAERIAPRHYIIPGPISAAAGQVHEGSKEERRRRRAERREKEEEDRQREARREARDTTGSEGHRAERVRRDNERRDKGYRDKEYRDEEQRARRHNCEVRYRSTENGVKDQHRSGGERGSRGHKKPEPRPPRWNSYSKPPTTDATCAKFQKHNQKPAEKLQATSYMSSVPSSPAYVADLRLAKTWRDGEETLGKANDTSGFTNDLRHFDSAQAFSNYQNLDNLKHNFVDDRAAIFTDYESEKLDLDAELRAAEAQLQALLLDGQSQNDPAVMSGANYMLDSAAHDKSATRRKSAVPRPLQTLPPRTSLSSSRQYKHKKSSSTSSSTRTYIPERSSSKRHSALSSLSSSASSSRDKKHHDSRNSKERADKPTLQRLRHVLGAAAGGRRASTGSDVSFGCVDSNRIIAGAEPRRGVYSGGDKHQEPLYVNGTNHVSHESEYGNGQSVGNWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE36</accession>
    <name>A0ABR3ZE36_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NADH dehydrogenase [ubiquinone] iron-sulfur protein 5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Complex I-15 kDa</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">NADH-ubiquinone oxidoreductase 15 kDa subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Cpir12675_001698</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion inner membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the complex I NDUFS5 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000028">
        <property type="protein sequence ID" value="KAL1898945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd24141">
        <property type="entry name" value="NDUFS5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019342">
        <property type="entry name" value="NADH_UbQ_OxRdtase_FeS-su5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15224">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15224:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00031222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1898945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="91" mass="10307" checksum="97B223F707995AAC" modified="2025-10-08" version="1">MATLLSGVGRCFPFWQEVLACYVVNSSSEDKEGKKKCAPAMEDYYECLHNKKEIARVMAMKQAYRAAEAANRKAMTPSREQIESLGLIRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE67</accession>
    <name>A0ABR3ZE67_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Microsomal glutathione S-transferase 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_001706</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000028">
        <property type="protein sequence ID" value="KAL1898953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.550">
        <property type="entry name" value="Membrane associated eicosanoid/glutathione metabolism-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050997">
        <property type="entry name" value="MAPEG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001129">
        <property type="entry name" value="Membr-assoc_MAPEG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10250:SF26">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10250">
        <property type="entry name" value="MICROSOMAL GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
        <property type="entry name" value="MAPEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="MAPEG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1898953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="149" mass="16284" checksum="34B03218C65B53CD" modified="2025-10-08" version="1">MSVISEIPREFGYVLSVAATSFFLNTALSFQVSAYRKAAGIKYPIAYANDELAAKDPKAFQFNCAQRAHLNYCEAHTSWLGALLISGLRYPVASASFGTVWIASRALYGRGYAMKGPEGRLGGAYLGFFADIIIKSMAMFTSVMFALDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE84</accession>
    <name>A0ABR3ZE84_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_001625</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000027">
        <property type="protein sequence ID" value="KAL1898966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
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        <property type="entry name" value="CID_dom"/>
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        <property type="entry name" value="ENTH_VHS"/>
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    <dbReference type="InterPro" id="IPR051485">
        <property type="entry name" value="SR-CTD_assoc_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000061">
        <property type="entry name" value="Surp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035967">
        <property type="entry name" value="SWAP/Surp_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23140">
        <property type="entry name" value="RNA PROCESSING PROTEIN LD23810P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23140:SF0">
        <property type="entry name" value="U2 SNRNP-ASSOCIATED SURP MOTIF-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01805">
        <property type="entry name" value="Surp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109905">
        <property type="entry name" value="Surp module (SWAP domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="CID" evidence="3">
        <location>
            <begin position="528"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="63"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="501"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="598"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="743"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="98"/>
            <end position="108"/>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="512"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="616"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="764"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="794"/>
            <end position="852"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="852" mass="92229" checksum="F00E5F3CAEEEF79A" modified="2025-10-08" version="1">MSDNSKKDSNDTPPPHFPDAEAKIVKIITKSAFDKQKADAHAKRQREAAEAAAIYDEFVKSFDADEQQKKPEGLVSGSGSGVPRLAGSLKHNNPMATRPEHWPQDKPKGFANASNDGFKGRFGPTSASSTAPKSGPGSLGPVPVSFSSKKRPLEGSASSRAKLGFEDYTTTTTTNTLTTNTLAPTKTATNNTPASTHKGLKPLAKVFNTSDDEGDTPSPHRDEVPISRPTIRLAQLPPATSLAFVRKLIPSTLVVEDVQLVPATSAAGSASTERKSTVAIVTLAQDTPATQIDTVVSELQNKYLGFGFYLSLHRHLSSSSVASSLVSSGATAIGSSGISTQPFGAKKIHRNSGAHRGSRGFAPPTSYWPSSSADGHSQQGLFHVPVKPPSDIRIVRTINKVLEQVLEFGPEFEALLMSRPEVKREERWAWLWDARSVGGIWYRWKLWEIVTSSSSAALRDNGRNGNRFVPLFDGGHAWKVPKHGLPYEYATQIDEFVSDPEYNSDSDSDACGLDRERDRHGDREQTFLNPLEKARLIHLLARLPSATTGLQKGDVARVTAFAITHANRGAAEVVQMVVTNIRKPLALMGAARKYPSHSLGNDGEGNYKPSDFSAEGNDRLSDSTKDKNQIRDKGIVGSSAGSDTSSASLVGLYIVSDILSAASNSNVRHAWRFRQLFEVALRESHVFAELGELAAKFCWGRLRADRWKRSIGAVLSLWEGWCVFQAETQAELVRTFEEAMDGGRDADGGADEEADGYKGAGAEGRSRWKSMENLRASTEARPEPLPVSNLDTQDTMEADGEDEDGADVEGEPMEESDVEGEPIGDIDSDGEDVEGEPMLDDVEGEPIDEDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF66</accession>
    <name>A0ABR3ZF66_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Calmodulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CMD1</name>
        <name evidence="5" type="ORF">Cpir12675_001695</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000028">
        <property type="protein sequence ID" value="KAL1898942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="match status" value="2"/>
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        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
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    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
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        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF0">
        <property type="entry name" value="CALMODULIN LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM01184">
        <property type="entry name" value="efhand_Ca_insen"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="8"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="44"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="81"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="117"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00020786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1898942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="149" mass="16979" checksum="086C0E613722A433" modified="2025-10-08" version="1">MADSLTEDQVSEFKEAFSLFDKDGDGQITTKELGTVMRSLGQNPSESELQDMINEVDADNNGTIDFPEFLTMMARKMKDTDSEEEIREAFKVFDRDNNGFISAAELRHVMTSIGEKLTDEEVDEMIHEADEDGDGRIDYNEFVQLMMQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF70</accession>
    <name>A0ABR3ZF70_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">3-hydroxy-3-methylglutaryl coenzyme A reductase</fullName>
            <shortName evidence="9">HMG-CoA reductase</shortName>
            <ecNumber evidence="9">1.1.1.34</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">HMG1</name>
        <name evidence="12" type="ORF">Cpir12675_001466</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(R)-mevalonate + 2 NADP(+) + CoA = (3S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:15989"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36464"/>
            <dbReference type="ChEBI" id="CHEBI:43074"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.34"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Metabolic intermediate biosynthesis; (R)-mevalonate biosynthesis; (R)-mevalonate from acetyl-CoA: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Endoplasmic reticulum membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the HMG-CoA reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.34" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000023">
        <property type="protein sequence ID" value="KAL1899350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004420">
        <property type="term" value="F:hydroxymethylglutaryl-CoA reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00643">
        <property type="entry name" value="HMG-CoA_reductase_classI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.770.10">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl-coenzyme A Reductase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3270.10">
        <property type="entry name" value="HMGR, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.420">
        <property type="entry name" value="Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025583">
        <property type="entry name" value="HMG-CoA_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002202">
        <property type="entry name" value="HMG_CoA_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023074">
        <property type="entry name" value="HMG_CoA_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023076">
        <property type="entry name" value="HMG_CoA_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004554">
        <property type="entry name" value="HMG_CoA_Rdtase_eu_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023282">
        <property type="entry name" value="HMG_CoA_Rdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009023">
        <property type="entry name" value="HMG_CoA_Rdtase_NAD(P)-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009029">
        <property type="entry name" value="HMG_CoA_Rdtase_sub-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053958">
        <property type="entry name" value="HMGCR/SNAP/NPC1-like_SSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00533">
        <property type="entry name" value="HMG_CoA_R_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10572">
        <property type="entry name" value="3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10572:SF24">
        <property type="entry name" value="3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00368">
        <property type="entry name" value="HMG-CoA_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13323">
        <property type="entry name" value="HPIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12349">
        <property type="entry name" value="Sterol-sensing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00071">
        <property type="entry name" value="HMGCOARDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82866">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55035">
        <property type="entry name" value="NAD-binding domain of HMG-CoA reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56542">
        <property type="entry name" value="Substrate-binding domain of HMG-CoA reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00066">
        <property type="entry name" value="HMG_COA_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00318">
        <property type="entry name" value="HMG_COA_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50065">
        <property type="entry name" value="HMG_COA_REDUCTASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0521">NADP</keyword>
    <keyword evidence="7 9 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="257"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="293"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="383"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="466"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="11">
        <location>
            <begin position="228"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="668"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1123"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1123"/>
            <end position="1145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1899350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1166" mass="125377" checksum="776283B117C438E7" modified="2025-10-08" version="1">MMGNLLPRRFRGEQPASQVVAPSWLNKKVTPFINLLSRLACSHPIHTVVMVTLLGSTTYVGLLQDSFFDVTFNVGKADWSLLAEGSRTLTANPENSWKWKTVEDEFLVGQDSNHLALVTLQFPGASSAPLVNAIPHADNISLDSLPASSELDSSLVFSLPYTEAPDFLLAAQEVPAENEEARAIEDEKEHRMWIMNAAKVSPRSTIIEWARNAWSGFVDLIQNAETLDIVIMVLGYLSMHMTFASLFMSMRRMGSNFWLATSVLFSSIFAFLFGLLVTTSLGVPINMVLLSEGLPFLVVTIGFEKSIALTRAVLSHAVEHRKRKDETKTKTKDSDTSSIQYAVQAAIKEKGYDIVHDYAVEIIILVLGAASGVQGGLQQFCFLAAWILFFDCVLVFTFYTAILSIKLEINRIKRHFNMQKALEDDGVSHRVAANVAKGEDSVDGSESQGTMFGAQLKRTSIPKFKVIMVSGFVLVNVMNLCTIPFRNSNSLTRITEWAGGSTSLITSQQPLDPYQVASKALDTILSNSESTSTPVTVTVLNAIKYELVYPSVHYGLPLTSDPENTNGEDSLHSYGVGGRMVGGVLKSLEDPVLSKWIIIALAMSVALNGYLFNAARWGIKDPNTPATHIDRTELALAQNFNDSSNVNMTLGEYMPPSVRQTPVLKSFTPAPTDDEEDTLSMKPIVPKPDNDTPPRPLADIEAILKADRAKDLTDEEVVLLSMKGKLPGYALEKKLKDFTRAVKIRRSIISRTAVTEAITSGLEHSKLPYERYNWERVFGACCENVVGYIPLPVGVAGPLVIDGQSYFIPMATTEGVLVASASRGCKAINAGGGAVTVLTDDGMTRGPCVGFETLERAGAAKLWLDSDAGQAAMASAFNSTSRFARLSSIKTAIAGTNLYIRFKARTGDAMGMNMISKGVEHALETMRGEGFDDMHIVSVSGNYCIDKKPAALNWIEGRGKSVVAEAIIPGTVVKSVLKSDVDSLVELNINKNLIGSAMAGSVGGFNAHAANVVAAIFLATGQDPAQVVESANCITIMKNLNGALQISVSMPSIEVGTLGGGTILEPQTAMLEMLGVRGPHPTNPGENARRLARIVAASVLAGELSLCSALAAGHLVSAHMQHNRSAAPSAAPSAAPTRANTPAPNGTGTPSLGMTMSAAAQERAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFG6</accession>
    <name>A0ABR3ZFG6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001603</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000026">
        <property type="protein sequence ID" value="KAL1899047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF7">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="106"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="356" mass="39014" checksum="1D1E19EF7AF3E0AF" modified="2025-10-08" version="1">MAIFKRSPRSHDQARVGKSVKSKRSVFGLGISRNPDPGGSHGKQAPSSKAPLRFPSKKALPKAPPKVPPKTAKPSAAPPRKISTGRNHRRLSDEMELPLPSPSPIVTIVVGPEGRVFAAHEDVLCQSPFFAAACRSGLLECVNKRIALPDEEPEIFSAVLEYLYKKDYYPRLIRNKVSDSWELEDSDMSEATPYAPLTSLGATSSELRRNSKQSKRQSTSSTASSVEATIRLSSYAQPLLRDTAIYCSADIYGLEGLKKLALRKQGLQSGIDVATTLRSAQYAYTKTAETDSRLRAHYLALIIHCRDTFKRSGTMQADMEAGGSKLYFDLFVALCNHIDDLMEVARMKGSLGLKGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFW2</accession>
    <name>A0ABR3ZFW2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycerophosphocholine acyltransferase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Cpir12675_001703</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GPC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000028">
        <property type="protein sequence ID" value="KAL1898950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021261">
        <property type="entry name" value="GPCAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31201:SF1">
        <property type="entry name" value="GLYCEROPHOSPHOCHOLINE ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31201">
        <property type="entry name" value="OS01G0585100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10998">
        <property type="entry name" value="DUF2838"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="157"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="315"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="453"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="20"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="464"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="504"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1898950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="527" mass="60234" checksum="152E64F63459C296" modified="2025-10-08" version="1">MDTPSPPSIANNGDSERQRSSSVDTSDEAQTPNTNKRPRISRNSSFSAESSYQDEWEGFPPLDRLTILDILDNFALSQHFEKLQRSISIQREKVRQSQQALKSHGSHARERMVEEWRRRAPSAEEQLERYRQRMRRGVEDLGNRWSDTKAITVREKISFICGVMNVFISGYLLGSFPQYFHIWYTAQLFYFMPFRGIAYHRRGYHYFLADLCYFVNLLLILSLWVFPNSKRMFTSVYCLAFGNNAVAIIMWRNSLVFHSFDKVTSLFIHIMPCAALHCIVHLISPDLQQARFPAAYAIKTAPTDSPNNYATLTSMLAWSSIPYAIWQLSYYFLISIRRRDKILAGRPTSFTWLRRSYAKAWIGRIVLAQPESLQEPIFMVIQYFYAVLTMIPCTLWFSSMTASTLFLSLMFTWSVYNGATFYIDVFGTRFQKELEALKADVARWQHASEVERLSGPGPIEYPAASTNSSDHPGNIGSHQEATDPGTSNHNTEGTSPKIVPQLLVNGSTNPISSSIEGNTTGGLQQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFZ2</accession>
    <name>A0ABR3ZFZ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">COPII coat Sec23p-Sfb3p heterodimer component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">SFB3</name>
        <name evidence="16" type="ORF">Cpir12675_001573</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle</location>
            <location evidence="2">COPII-coated vesicle membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SEC23/SEC24 family. SEC24 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000025">
        <property type="protein sequence ID" value="KAL1899289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1670">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.730">
        <property type="entry name" value="Sec23/Sec24 helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012990">
        <property type="entry name" value="Beta-sandwich_Sec23_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007123">
        <property type="entry name" value="Gelsolin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036180">
        <property type="entry name" value="Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006900">
        <property type="entry name" value="Sec23/24_helical_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036175">
        <property type="entry name" value="Sec23/24_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006896">
        <property type="entry name" value="Sec23/24_trunk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050550">
        <property type="entry name" value="SEC23_SEC24_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006895">
        <property type="entry name" value="Znf_Sec23_Sec24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036174">
        <property type="entry name" value="Znf_Sec23_Sec24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803">
        <property type="entry name" value="SEC24-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803:SF4">
        <property type="entry name" value="SECRETORY 24CD, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00626">
        <property type="entry name" value="Gelsolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08033">
        <property type="entry name" value="Sec23_BS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04815">
        <property type="entry name" value="Sec23_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04811">
        <property type="entry name" value="Sec23_trunk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04810">
        <property type="entry name" value="zf-Sec23_Sec24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82754">
        <property type="entry name" value="C-terminal, gelsolin-like domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81811">
        <property type="entry name" value="Helical domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82919">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Zinc finger Sec23/Sec24-type" evidence="12">
        <location>
            <begin position="339"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 trunk" evidence="13">
        <location>
            <begin position="417"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 beta-sandwich" evidence="15">
        <location>
            <begin position="671"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 helical" evidence="14">
        <location>
            <begin position="767"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="domain" description="Gelsolin-like" evidence="11">
        <location>
            <begin position="899"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="35"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="140"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1899289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1054" mass="114097" checksum="1F9092B6AFC9C0EF" modified="2025-10-08" version="1">MADYGMFHALGQGEQLDPNDPSRTSQPVPAPFQPPVAANPYEKLQQQVPQQQPQPHLQQHQPYLQPSGPATSSAPPPHSQYGGHSPAPTLPYGIPPPPSQPNPYDLASQMAGMSLGPGAPPGAAPPPMTGAGSDALGATARRKKKDRHAYHTVEAPVGTSFGAAPSMGGGAPPDNFTGSGIPPIADSSSQFIPAASVTSPFSGSAPAPAPAPASATSPIFGGDPLPAPAVVPAVGPSTISADDTPGVPTSRDSLQPFYFQNAYPTFERHVPPPATTSFVAFDQGNASPKHSRLTMNSIPISADKLATTGVPLGLILQPLAAQQPGELDIPVLDFGSSGPPRCHRCRAYINPFMMFRSGGNKFVCNLCTYPNDTPPEYFCATSPAGVRVDRDSRPELTRGTVEFVVPKEYWTKEPVGLRWLFVIDVTQDAVNKGVLETFCEGILAALYSADADGEAGDSDKPPRSVPEGVKVGFMTFDRDIHFYNCSSSLEQAQMLIMPDLNDPFVPLGSGLFVDPYESRSVITQLLTRLPEMFSSIKNPEPAMLAALNAAVSALEPTGGKMITSLSCLPTWGPGNLFMRDDGKTVGGEPDKRLLTTEHPLWKKVVERMVPAGIGADFFLVSPNGGYLDIGTVGHVSALTGGEAFYYPNFVAPRDGKKMALEIKHAVTRETGYQALMKVRCSNGLQVSSYHGNFIHHTFGADLEIGVLDADKAFGVSFTYDGKLDPKLDAHFQMALLYTTASGQRRVRCCNIIASVNDNPRDAMKFIDQDAVYTLLAKEAATKLATTGATLKDARNFMTERTIDVMACYRKNFLAPSHPPSQLVMPDRLKEFPMYMLGLNKTRAFKAGTETSDRRVNELRLIRSIGTREMSLYLYPRILALHNLQPEEGFPDAETGHLKIPPAMRASFSRVEAGGVYLVDNGQVCILWLHAQTSPNLISDLLGDQYTSLKEIDPYMAELPVLQTHLNAQVRNIVEFLRSLRGSKGLTIQIARQGLDGAEYEFARMLVEDRNNEAQSYVDWLVHIHKSVQHELNGSRKREDASESTFAGLRAPYWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG51</accession>
    <name>A0ABR3ZG51_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_001354</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000020">
        <property type="protein sequence ID" value="KAL1899676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327">
        <property type="entry name" value="RING FINGER PROTEIN 127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327:SF51">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR OF YEAST FORM ADHERENCE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SPX" evidence="6">
        <location>
            <begin position="1"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="367"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="461" mass="52890" checksum="479204958A1D7EEB" modified="2025-10-08" version="1">MKFGHDFKEALQREDANSDGNLIGFPEHWIQHAIPYSQLKKCLKKILNELREFGLDPEIIKQLVSPSVDTGIKLKYDLEESSKLHALQPKLTIFVHVRDGTPIDVTLTPTSKRILQRILERQNGMEQDDDDVGLDLSLHESNDTQLKLSRQPSATLLAPVPTGSSEVLKVPLHFDAQFFEMLQREMTGLESIQAQEEKVISNEITSLRNVVAIVSRPSRFSRTDVDRWREVFNIYIEAEVFFSTCETSSGTRNSTDALRKLHWFQNETQKRQLNNGFLRSQSRDAFSRFLQLNVAILKNMQFQEINRMAVMKILKKFDKRTSFGISKVFPQATESKRIMSGSIAKDMCAAVSSQLVSLVPQLNDYLCPVCFAITWRAIRLSCNHVYCIRCVIKMQRRHDNCPLCRSNTIGSACTDNLDSQLENFLKKNFRAEVNEKSVADEVEYGIEQYGDKYRKFSCIVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG56</accession>
    <name>A0ABR3ZG56_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Protein SYS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_001571</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SYS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000025">
        <property type="protein sequence ID" value="KAL1899287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019185">
        <property type="entry name" value="Integral_membrane_SYS1-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12952:SF0">
        <property type="entry name" value="PROTEIN SYS1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12952">
        <property type="entry name" value="SYS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09801">
        <property type="entry name" value="SYS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="153"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1899287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="195" mass="20813" checksum="CF91221B00CD7314" modified="2025-10-08" version="1">MARRRARRPGAISELPPLRILTQLALLQALYYAVALLLTVFSSLVAGQPWKPALVFGWADVRGDVTTGWLLALLMVLDGGVVVGSAIVVLVGRSKLVPDFAISTQAIHLAVVYLFNGMPRNNMWWMAAGCSAAVASFLGIIGSRSRELQPISFGGRSRNGNGAPPAVEEADEAGLPRLPARDGAGDYEMVAMTQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGR5</accession>
    <name>A0ABR3ZGR5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">NRG1</name>
        <name evidence="4" type="ORF">Cpir12675_001418</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000022">
        <property type="protein sequence ID" value="KAL1899382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="263"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="292"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="120"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="397"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="460"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="516"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="120"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="344"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="397"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="463"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1899382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="569" mass="62617" checksum="E35F6924771DBEF4" modified="2025-10-08" version="1">MKRQANLPPISTSLHSSSQIPLYVSLPPPGSTTSASPGSDYMHNPSPRAAMWSPKTRQDRDRMDIDRMDIDTPTSAGFCNSAESASSFVSAFFPQNGHDPFQAAESLTMDYRSISEHIRRHRNSHALPRSHTRSQSQSHSRSRSHSHFHSFSQPQSPVRSSLNHRHIRRSSDSDSTTATESQRRLASFASLSSLEAEYDEESGFAGDFELPLSQEPQSLSPIDRRRLVRALLRDKARTNKGKKSKYSVPVSYISDEGSIKKRWLCLRCGYPASTSGHASRHHNTVHEIDRPFACRLPNCGHGFKRHDNQVQHEKTRHNLDLDVPGFDPDGSQWRRAIAEEEASKHRRNVRRGPNHLRQKSSISSTSSDWYFDRAGMLPRAPVAIAPAPTPAPVPTLASAPVSTTASTKAPSKTSVKASDKTCLAATVNAPVSTSTVASDASAPPTRQDYRHSLVFLCGDDSESSQPSSAPHSVTLPPLAWTPRGSISSHSGDPSHRTHHRQLPSISLSHSSFQGSEYELSAAETSPAGRNSFCPAEPLGAAPHFQIPNYQQSVSYTQHHHQPATVWASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH45</accession>
    <name>A0ABR3ZH45_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001223</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000018">
        <property type="protein sequence ID" value="KAL1899724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="85"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="534"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="372"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="447"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="563"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="621" mass="64742" checksum="02C716B963E572C3" modified="2025-10-08" version="1">MFSSRKAPKALSAAAMTASAASVALNAMVATHTTSAQSTVHVLSIVGTAASGLAFLSLSGLYASHLLSTEDSPLRVLPSWVSRSLFASSTILSATAATFGTLSVIFIGQLASDVRIAGLSPVALLSTISVITLVGFLVQMALYVSIVSSRRPKYTSSSIDCESRLKDPKGSPSNIKSIRYSTTMPATSSPISTSTLTSNSPSMEKSMEKSFDARFFSSKISPAPTIRTLSHRSSPAATIRSHRINTPISPLPAVDLERVTSAALSISTVASGTTISSPIASPPGIAGALTPRPSSRLLPRVSLESLQSTTQSVRSLANTMSFVNSSVTSSQNPNIGSISSTLGDRSLENMDPAYSHTPTEAVSSSDTNALNSISSPSSTTCPTPVYNSRPILSRLLETIPQSPTAPIRSRVGHAVRSSCPESEYTGILDLPPVIDPDSAPRGRGRSRTQGATASPRMSSTTPNLHRSSAAAKPVEAEAHIHPLFRSDSPGPPPLATPGTVVLAAPAAGRVLASRVSIRSLRRIRSGSMPVVRSSLSRQSSVDDFNPATAVHDEMPPLEDLDSYDSSSFKSAETSNNVPGNVKRASKEGSEVGDGDSDGGSEVCEQALTPLMPDWVLSSNAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHE2</accession>
    <name>A0ABR3ZHE2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_001393</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000021">
        <property type="protein sequence ID" value="KAL1899622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17352">
        <property type="entry name" value="MFS_MCT_SLC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF177">
        <property type="entry name" value="RIBOFLAVIN TRANSPORTER MCH5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="65"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="225"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="268"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="398"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="5">
        <location>
            <begin position="64"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="432" mass="46600" checksum="D0D43267BFCCAD0B" modified="2025-10-08" version="1">MSSCDSDPTNQSGNKAPYFEPYSEKAVPIATETPQEPKCYQQEALEDLTRQRTDPSNYPEGGFKAWLVIFGSFCGATSCFGLMNTIGVIHSYIANNILEQYSDGTIGWIFSIYLFISMAGGVLGGPVFDLYGPRWMMTAGCILLTLGVMMTSLATEYWQFIMSLSILTGIGTSLVFTPSFAAPGHWFLRRRGLATGVAATGGSVGGIIFPLMLQQLIPKIGFQWSLRVLGFIIFSLSFTASLLVRSRLPPLPDSNVWPDTRIFKQAPFTLLTLSSMLMELSLFVPITYISSYAVDMGLGTGLSYKLVAILNAGSFFGRALAGFVADVVGRFNTLAFCIFACFVSCVALWLPAGNSVALLIVFAVIFGIASGSNIMVSIGPLIGVPVGGTILQANNGHYWGLITFTSVVYGASVVLVVIGRCVARDWKITTVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI69</accession>
    <name>A0ABR3ZI69_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">RNA-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_001035</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">May be involved in the turnover of nuclear polyadenylated (pA+) RNA.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000014">
        <property type="protein sequence ID" value="KAL1900351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12257">
        <property type="entry name" value="RRM1_RBM26_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1390.10">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002483">
        <property type="entry name" value="PWI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045137">
        <property type="entry name" value="RBM26/27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14398">
        <property type="entry name" value="RNA RECOGNITION RRM/RNP DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14398:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN SWM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01480">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="11">
        <location>
            <begin position="227"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="311"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="7">
        <location>
            <begin position="227"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="95"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="642"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="400"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="222"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00043866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1900351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="700" mass="77529" checksum="B5407A1F589F2822" modified="2025-10-08" version="1">MLLYNEADSPRLKEWIVQRLGDTSDADSDILADYILALLRHEGDLASTRELCESELKDFFQDGTDQASNFVDELFRVLDYKSYLPGALPQPPVPVKNSFEEFPSSVPTQPKNHNKRKAVDNDVSGPSASKVSRVSMDNEFANPRTAMQPWTGGYPTAMPGLPTRPPIAPGVNMESIANMNMNIDLNALANMAMFNQNLLAMFTGVGGISSGLDSETGGLAKGSKKSKKKKRRCRDWERTGLCSKGDSCKFSHGDPDLPFPMVDMSALMNLAANFQPLHDTNQKAVFNSKSQAGSVSGKQNKANRIYDFEPGRVFVRDIPTENFSEDSIREFFTQFGSITDVVLQQRNNSALIQFAEESEALAAIESPKPVFENRFVTVVPARKLRKADEPAEPEFDMEEIVKKQEEAQRVFEEKKKLRDELQKQLKDLERQETTIRMDQFDLKRKIAEKQASLVRKNGGGSNSDSDMEILRAQLAALEDEAVALGITPTNGTEYENGGDETGYEFASFSRGGLNGGDFRGRSRGRGLRGRGAFRGRFRGDIHQAYKGATLDNRPKTVAIKGVDFTVSTNSEALRQYLMAVGFFTDIQSTSETTHIMFDDRRTAETFWYGLAYNPIPGVAGELELSWVSNTAVGLLVTGTEDNKNGSIGDAGDEDNQGSVGDFPLKPDTGVSNTFAKKYEDDDRADMDYDVADEDDWNSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIB7</accession>
    <name>A0ABR3ZIB7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001163</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000017">
        <property type="protein sequence ID" value="KAL1899942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="30"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="72" mass="8429" checksum="72F1433B1D703CE3" modified="2025-10-08" version="1">MDSIVEMPHPMLPIPAAQDIDLMRYCNHIETSLRQENTQLKEKVSALELDLDDAKATRRKFQEEYNVLAFEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZID2</accession>
    <name>A0ABR3ZID2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_001180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000017">
        <property type="protein sequence ID" value="KAL1899957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1899957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="194" mass="20655" checksum="E8C96FFB1251E80D" modified="2025-10-08" version="1">MAPHLSSLQRSQVLALRASNLPLSQIAHRLRISIAQVRYTVRQNSANVAQRSGRPRLLSPEQVDRVVAFVSRSSNNQAIPWAGIAPALGIDCSVWAIRRALRLRGFSRGHALGRTALALRDRGEVQTLADSQTLGLSQSVQPTEHQMLSGVAKEGSLEHRVQAATAVAAAEAVAVATAAATGGTGPSFSHRMET</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ31</accession>
    <name>A0ABR3ZJ31_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000015">
        <property type="protein sequence ID" value="KAL1900071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="504" mass="55094" checksum="F31DC28EE497815E" modified="2025-10-08" version="1">MMRSLVPFPNGGEQQREEIVMDFHPSEDQEQEIQSSPPGLNGSLDNQHDLRLHPRSPSPSHKSEYSPNMTTTNRPAAGTCAIPDLGLTSPAGFINVFRLENCNRTDESSSGDSNNSDNRSASPNSEDLDRLAQIEATQILAHSMSSNSSAVPFSCSPRSSGSQQWDINIDDGNTPEYSAGNLPREESPPARNVLNEGFLPCNSVPPWSLTRLSYCAMSICEPSLGSAADNQSANITSNSDASADISKEPRENSPCVFPRLDDNVSLRYSYTHTTRNAVKDAFSRLKSLVNIIPLQPPPSGPSETSTTAMRRALISAAVQRVGSRDEADFSRISEETQAKGVMRYDDGSKPKEGDAEVEVPSSNEDRDKDEDETTDNLYESSLDINRPQPVHRVAQNDGSHEYNALQRRVIELELRVIIGELQIAHLGGQVDLFDQIDADILEEAVKTGANVLAMRREYLQSMHKDVLSPSSSQDKYCSDGDLDEVMADISDGEGVNESSYPSGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJB0</accession>
    <name>A0ABR3ZJB0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_000678</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Mediator complex subunit 22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009332">
        <property type="entry name" value="Med22"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06179">
        <property type="entry name" value="Med22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1900805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="141" mass="15544" checksum="5A1A06DE918F8F82" modified="2025-10-08" version="1">MEAQANITNMLDYHNRLVADVLARFRKLCIIATSRAAAVSTDLSSMSISGMSMDLEFEGLNKSIKELLTLSRRIKELWVFGPLGQEDVHARERAAAVELDVKHIAQIISAAEDGWLRGVVEDAGGSWMPMPKDDEAQNCPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJN2</accession>
    <name>A0ABR3ZJN2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CAJ1</name>
        <name evidence="3" type="ORF">Cpir12675_000898</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026894">
        <property type="entry name" value="DnaJ_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052814">
        <property type="entry name" value="Peroxisomal_DnaJ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45006">
        <property type="entry name" value="DNAJ-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45006:SF1">
        <property type="entry name" value="DNAJ-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14308">
        <property type="entry name" value="DnaJ-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="6"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="487"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="517" mass="56842" checksum="DF5E5AE14C5FAA4D" modified="2025-10-08" version="1">MVADTAYYDTLGVAPTATELEIKKAYRKMAIVHHPDKNPNDPTASEKFQSIGEAYQVLSDPDLRKAYDKYGKDSAKPQEGFVDPSEFFTSIFGGEAFLDWIGEISLMKDLTATMDIAMNEEEEAAAAADVEEEAALKKPDAPKETAPTADDEFPGMAEALKASLQDIEDNSAKPADSHSTSTPQSPTSASASAPAAAAVSQEDEKHKPALPPRTSQAGLNRKAIPIRPALMASEHVEPEATSTDLNDAENKKKKAGLTKEQREQLAALEAERQRVREERVTKLSQKLLDRISVWTETDKSIDVTRAFQTKMQLEAEELKMESFGIDILHAIGQTYLSKGTALLRSQKFFGIGGFFSRMKDKGTLVKDTWNTISSAIDAQNEMEAMAKMEQQGGEEWTDEKKAEYERRVTGKILTAAWRGSKFEIQSVLREVCDTVLGDKKASSSKRLERAQALVLIGDIFVKTHRTAEEEGDYLVFEQLVAEAAIKKEKKKEPKGGKSKHEHAAAMAAENAPNVPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJT5</accession>
    <name>A0ABR3ZJT5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">U1 small nuclear ribonucleoprotein C</fullName>
            <shortName evidence="8">U1 snRNP C</shortName>
            <shortName evidence="8">U1-C</shortName>
            <shortName evidence="8">U1C</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">YHC1</name>
        <name evidence="11" type="ORF">Cpir12675_000885</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">U1 snRNP is composed of the 7 core Sm proteins B/B', D1, D2, D3, E, F and G that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins U1-70K, U1-A and U1-C. U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the U1 small nuclear ribonucleoprotein C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03153">
        <property type="entry name" value="U1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000690">
        <property type="entry name" value="Matrin/U1-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013085">
        <property type="entry name" value="U1-CZ_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017340">
        <property type="entry name" value="U1_snRNP-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31148">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31148:SF1">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06220">
        <property type="entry name" value="zf-U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50171">
        <property type="entry name" value="ZF_MATRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8 11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Matrin-type" evidence="10">
        <location>
            <begin position="4"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="62"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="121"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="166"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1900419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="213" mass="21736" checksum="85184A3B6A358D12" modified="2025-10-08" version="1">MPKFFCDYCDVYLTHDSMSVRKAHNSGRNHIRNVVDYYERIGHEKAQSVIDSITSSYAAEGQAHNNPLLPHNQPGGGFPGGGRPAPYGFPGGVPPPFPGAPGSFPPGVPPPPGVAGRGLPPNFPIPGPNGLPPLPNGLPFPPPGGLPFPPPIAGAAPGAPGSQGPPTFPPGHHFPPPGVGAPPAGMPPPFQIPPGMPQLPGFGGFAAPGMEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK72</accession>
    <name>A0ABR3ZK72_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Orotidine 5'-phosphate decarboxylase</fullName>
            <ecNumber evidence="3">4.1.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">OMP decarboxylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Uridine 5'-monophosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_001165</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OMP decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.23" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000017">
        <property type="protein sequence ID" value="KAL1899944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04725">
        <property type="entry name" value="OMP_decarboxylase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014732">
        <property type="entry name" value="OMPdecase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018089">
        <property type="entry name" value="OMPdecase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001754">
        <property type="entry name" value="OMPdeCOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32119">
        <property type="entry name" value="OROTIDINE 5'-PHOSPHATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32119:SF2">
        <property type="entry name" value="OROTIDINE 5'-PHOSPHATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00215">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00934">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00156">
        <property type="entry name" value="OMPDECASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orotidine 5'-phosphate decarboxylase" evidence="11">
        <location>
            <begin position="37"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="160"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="449"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="170"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="207"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1899944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="501" mass="53705" checksum="0AD460AD117A0835" modified="2025-10-08" version="1">MQPPHPTLRSKYADRAERASHPLVSYLFRLMDLKASNLCLSADVSTARDLLSLADQIGPSIVVLKTHHDIIAGWDYSPNTGTGAKLASLARKHGFLIFEDRKFGDIGNTVQLQYTGGAARIIEWAHIVNVNMVPGKASVTALTEAANKWKERHPYEVKTTVTVGTPRADSDDEDDDCDDCDDPANKTHTTSNGNGTGNGNGYISAPRNGTRTSNNGDQEDIPPHIVHNAPKSNTSNPAPSSNSNGASNGNSLFGSFRLDFDGKPSLSHEGRKGSIVSVTTVTQHYEPADSPRFTKNSTGEDEVLFPGIEEAPNDRGLLILAQMSSKGNFMGPEYTQACVEAARENKSFVMGFVAQSPLNSLPEDDFIGMSPGCQLPPQSEDFDGSCQIVGGDGKGQQYNTPSKLICQSGADIIIVGRGILKADDPPSEAERYRSAGWKAYLRRLKNDSKMDAGTGDLEVPVITTGDHMEVDVEASEANADGNSSSSPHGMKRKRSAGSVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK98</accession>
    <name>A0ABR3ZK98_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoglycerate mutase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000008">
        <property type="protein sequence ID" value="KAL1901131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051710">
        <property type="entry name" value="Phosphatase_SH3-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16469">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16469:SF27">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="620"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="800"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="119"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="626"/>
            <end position="669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="855" mass="91709" checksum="235A0CC3E92BA73C" modified="2025-10-08" version="1">MAKPPAYIFVVRHGMRLDVADKTWAESSPTPYDTPLCYSGWIQARAVGARIASILAQAEAESDAPQSPTLSPSISSTTSPQTPRRRRFKVAIHSSPFLRCVQTSIGISAGLAQPITTGPPTVPTTRRGSPNPVVIPSPILKPTGSGSTRPNLGSLESLDSQHHHHFHKAILRLDEYLGEWLSAGYYETIEPPPKSSTMIANSKAQLLKREIYAKNFNQSMTSPVAAPHLAPLLWTGGRATANTVAVPEDPFEGQDSDPETEDLPPPRPLGELGYIAPVPHYAISSSDKIPDSYVAHARDSCIVFDYQWESSGPDLDWGDGATFPEEWTSMHNRFRKGLQGLVDWYSTTEDAADIAHIRGAAEKDKIEDTWSEDGDDDVDIESVVIMVSHGAGCNALIGAMTHQPALMDVNMASLTMAVRKTGSEYEHMSPWLPNSDQTDDTSLHTVKNSIPVHQYYDMRLIASTEHLRTASSSAGLVRSGVIPSWSFGINKPVVSRGRVSTMTSSFAPPPVVAPKILSRPENSMWSHNRSSSMSASFGLPEIGLFSPRKEDDADYRFSSANQGDVASCSNDNISGGITIGSGVTSFMKKRDDGCMTKNMEPAPTPAAKLASSNIKVLSMKSSSDATSTGRLSSPLSTSGSYSGGVLPSNSRTATATTAPSSMASSISSLPPLALSSNKGSSGLWGITNRKTSGSSVLMEDDDEDNFFPDFENKRKFTPPISQNASRRTSPTLAFKSTLSSMHSPLASPTFVPLSSDCSMETKPALSATTNALPSFEISLTSFSETATTNMNSTSTLASRASRLDNSPVRSPIHSPMGSPIREPLISPFFGDTSGNVEPVIRSRISTSRMWGAPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLL5</accession>
    <name>A0ABR3ZLL5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">NADP-dependent malic enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_000470</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the malic enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05312">
        <property type="entry name" value="NAD_bind_1_malic_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="entry name" value="Malic enzyme, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001891">
        <property type="entry name" value="Malic_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010052">
        <property type="entry name" value="PRK13529.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406">
        <property type="entry name" value="MALIC ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406:SF32">
        <property type="entry name" value="NADP-DEPENDENT MALIC ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00072">
        <property type="entry name" value="MALOXRDTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Malic enzyme N-terminal" evidence="6">
        <location>
            <begin position="259"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="Malic enzyme NAD-binding" evidence="5">
        <location>
            <begin position="449"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="164"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="178"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="757" mass="82680" checksum="736E9A2F31A5876F" modified="2025-10-08" version="1">MASCSFSASSTSNISTPRSHSPCPSASTTDVASAPYSQFMPGSSPPSLSSTSPSLPSSRAPASTAHDSTTNQATMSSFTNVSAIEQAMQMSSLDQFKGYMQATFPEVQQANLTQYSTEAEASGYQILREPVWNKALPLSYSSSRFISSSAVHSRPPAAAAAATISSSMFPPTPPPLSSSPSSTMSSPSSDSQPPLAMSDRKLILGQGLSFTPEERINKNLTGLIPHTMESLSTQCARAMKMIHTRQTPIDKYLYLSSIKDQNVDLFYRLLMDHVRELMPLVYTPTIGDVCLQYSTLYTRPEALYISIKQRKSIRTILKNWPYPNPEICVVTDGSRILGLGDLGVNGVGISIGKLSLYTAAAGIHPSKTLPIVLDCGTNNETNLKDPFYLGLRDKRPSVQVQQEFMDEFMVAAREVYPEMVIQFEDFESEKAFNYLDRYRDSYKCFNDDIQGTGAVVLGGYIGAVNLSAVPIEEQRLVFMGAGSAGVGVAKQLVEYYTRRGLTEAEARDKFWLVDTKGLVTKDRGDKLASHKVYFARTDNEGQQYRTLEEVIEYVQPTALVGLTATFGVFTESVVRALKKSVDAGGKGRRPILFPLSNPLTKAECTFEQAVNWTDGTVIFASGSPFSSFSVKTANDNVITYHPNQGNNVYVFPGIGLGAILAKASKVTDSMIYTAAAALSESLNADEIHKGLIYPEIERVRDASMVVAREVMKAARRDGVSELPEAQWAEFEEWGDVSLTAYIESKIYNPTSFGESHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLQ2</accession>
    <name>A0ABR3ZLQ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000792</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="522"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="265"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="637" mass="69600" checksum="E60268D42F806CDC" modified="2025-10-08" version="1">MSPSDPFDERRMKIFPGAEVVNGAVVTRSILPFHETAQNPPILLETALKQGPEQPSESLYPLVLYIARVAGSKNIILSNLKPGHNSVTRTDVENSLYFVQQLDPTEPFLAATSPIDVDSPASTQASSNQDPKDSPAKSDFLPPPPLQEHPIFRQTSQFSGHVPESSAPSRNSVTAAAPSPNQLPPPPIVTGIRRKPIPPDLETRRLSALSALDNPLATKKPDVETDARPPVSPYLREIMEAGARRRGAASNTLSQSCTSGPSRNSMPSSPPLLQSESPPLRSSARFHISLARPKSSGCPSSSNVYLSAHGYPTPRNTPSPSISPRNSMLPSINTNISGTVTLPQAMGMSLRLVRWHHSTSQTWPVAHLVSAPLAPTTKEMRRKSLGASTTTTIPPLRIILDNPGYAPFADTPSKVFHQRADRTNLPMLVRDVDMSYEKSWTKRLLQHSRGKKSESSCNGHSHGYSRNSSSDEDTSVNLTAGPGLKKDGYTFMTPWDTRCFFRTGKAGTSLVCYHAVPIQQSRARSRSHSHSRNSMASGFGSPEKEEKKRFREIPVSELRFNLPGMSLFGTPSGENRSHFPIAKETPNWLGKEKAGGGRHGDHAKMGKLIIFEGSKDMVDLVVAANVGIWWRSWEITH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLS5</accession>
    <name>A0ABR3ZLS5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000558</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052973">
        <property type="entry name" value="Fungal_sec-metab_reg_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392:SF3">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="600"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="736" mass="83897" checksum="604DFBFFD96ADC87" modified="2025-10-08" version="1">MPKKFCFAGNRTENIDYAYPDPNSAPNLTTPSNFPNLTPYISEGSPSFILRSEAEAYPSKNNELDIPIRPLLGQNDMPQMEQILTQQGFQTDLSQGNMLETQYNPVQPNFNQNIPELAPGQGDMQQIQQNLIQKVPQPNLMDLSPAEHSLLDGYDLESWAASPSPSAIPFNPVIYMPIQAPLEFPNVVDRYGAVPEAPYLVDAPPKSPDQIQGLVWYKHEMPQDNRFDLPAGQNMIPPNQFNPMPSKEQHPFQDSLPPTTPHNHSARAQQPPSQDSLPPKAPPNGESAANVSRPMLPGSVPIQPSKKQRGSFTLSLRKETAETRAIGSCVRCQMQRIRCVINKKDREGECATCESARPNTKFWRLPCLRYKITGVELYKPLTNLQDLAWTKRGTTELLEIKNFRWQSTQMRTIWLADGHTDISIKLTVRRFLPKDGDKMKRTWVTSNGELRSVDATPYAISDPDAAYRELEKHLSEMAYQCMQKVVLPLGEVMFKTYSIASDASKDPKVSVDEKSLLQCTLKLWMSIRLTTTSQHIIGEDTLDMQNVSDDTSPLYGKVPVPPVLGAQVDVLLIDRIQNQLRQKVLKLLKEMILRNKKQEWFSLYLAIFIIMHNIALIIAHDALYARKHGLKRRYARPERVQEYHKGANTILGYFHYSNKSHYPFSSECKDQGLKALVELDDKRMQFIQDTRKYVRSKEAEWQEMREQSQNGNDFFYVSQLFQKEWKPMDIDTSASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMB7</accession>
    <name>A0ABR3ZMB7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">separase</fullName>
            <ecNumber evidence="2">3.4.22.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ESP1</name>
        <name evidence="7" type="ORF">Cpir12675_000540</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>All bonds known to be hydrolyzed by this endopeptidase have arginine in P1 and an acidic residue in P4. P6 is often occupied by an acidic residue or by a hydroxy-amino-acid residue, the phosphorylation of which enhances cleavage.</text>
            <dbReference type="EC" id="3.4.22.49"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.22.49" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005314">
        <property type="entry name" value="Peptidase_C50"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030397">
        <property type="entry name" value="SEPARIN_core_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12792">
        <property type="entry name" value="EXTRA SPINDLE POLES 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12792:SF0">
        <property type="entry name" value="SEPARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03568">
        <property type="entry name" value="Separin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51700">
        <property type="entry name" value="SEPARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C50" evidence="6">
        <location>
            <begin position="1939"/>
            <end position="2036"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="35"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="94"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1103"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1277"/>
            <end position="1345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1458"/>
            <end position="1499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1905"/>
            <end position="1947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="45"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1106"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1287"/>
            <end position="1309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1320"/>
            <end position="1336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1466"/>
            <end position="1492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1905"/>
            <end position="1917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1926"/>
            <end position="1938"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="2146" mass="237075" checksum="A6C0494A79B2C28B" modified="2025-10-08" version="1">MTAASSSKTEQMESVISDLSSAANCSPATLRLLNSLLRPDDSPATKPTSRVTRSDKSATATSRLKPATSTNAHVLLQSERERFATQITNATLNALKTASPPIPTPADSPDVSLSREKLKENQPPRPASAQAPLSPRRPRALNRVATTIGSVIDNKPTKSPPTAPQSGCMCVVECARVALGILLASRPAGDPGIETAAFTFVGRLLALGLDNEALVDLRAFRRRLDMILAKTTKAVMKPLAKDASAVDIMAFIGCEIPVTLKPLVAMAQLHALRLLTMSKKPKLVEAAIPTLKFQEPGSPTQTAASLIMTSPATASKYIRQLETITKMILALSPSWSSKDDAEAFDHLKHPHPTKAFELQCIGLLSAHLVIQYQEQSADYYPKIIVPLSKVFSALKRRGELEGGAYNAASSYYKMFQTELEPKMGKWPGPEDPCIMSIHLTLGSLAATAGHISESTKWIQSVHELMIPDINSIRYTSVSAQLLAVMLKHSTVSPKAVEISTAVVSGLEGTVKGEMSELEQLTLDLNTLRRRALRFLLTTHQPSNTILIGNLEVLCLQFPRFSARWLGKPPAEDAQQKDTIRFEQRRQLLVYHAESIVDGCIMILKRRLDAGTQEWLALNSTLQYCLDFLQRMGDFPSQAQDEGIMSNQYIKISGLYFLYASKTRGAKDKTKQANGLKALRRSIEAMNGRPASEKEKAKYTAKLEKLAESYKHFGHASEARSILSKLCHNLAETGILADVALLLEAKSPSVAWNKHGDIIILSRTLIALARLGNTDDSWMDGLPVLEQAALLEHRLHISSGTMKNSWAMIQESADRLAQIYQNTNCHFRHLRSLVFLYERVFAHGDNCTDISAQVLEAKQQLDSKGYGQDDKLSPYFNETWAYYKSIEMLRSPEAKLENFSEAIRGWRAAVSSAMSQSGSLEDVMSNPETLLRHLGAIREYATMKGESEILAHVLELSRDICISMASSPGNVLIYESMLGTHFLDIGDHAKAASIFSRKESQLDEDEGGPKDGHVAYYLASANYDMQRGDLEQAQINLNEAHRIFEANKSFISTTARVKFTSEASHLYSVLALNRGDSAQALEYARTSVKIIYQLWSRFEQFKTEDASSSPTPDSSNSTDELGSRAQGHGAEFWGLTSPMMRYLQRASAVYMYLGSFADTQYYAEQAYRVANSTGSLRYQAQAACWAASVLVKGDNLADAENYITVVKSYLVSVEPCVNSVSLACQLASIFRSMNYAEDEVAMLELANAHMSSIGVLGKGESTETELAGRMQELEIKEPPKSDKKMSMRTRSTTVAASTRSTRAKTVTSTSIAASSHARTRSTVSKKPTTTATTTTVTRKGRADTVPTKKPISEATQDAQIARPSSPLVSHMLKTKTSLILSQGLALINQKDYVGAYEILQEAGQVMLEATSSMERDVACAMCLIGRALEKMIRDPVFSVVQDSTLSFPAVCNANKVAADNGDVDMEPSEKPRSRAKETKETKDHVARQGRGERFATTGPSFTDDLREAQQLLVKANSVAAVCGDAGLVYRVSSLLQTTLIFLSATTADSNVVAHPSYASSTVEYARNVVWKREREASTCSFSLLTEWPPVLEDTTSQQNKAVEGYGDIARFQQDYVDILPPEWRAISLALSENKNDLCITKLQAGHTPFMLRLPLERATSREMDVDVFNFSQGHAELLEIVSQSNESCHSAKKMVDKESRAEWRRQREEIDERLESLLANIEHLWLGGFRGIFSQHRRRTDLLAKFQQSFQDTLDKHLPSRRRIRGRKAPSSITLDPRILDLFVGLGDPADHSNSEYQLYDIDEALTDLLYFVVDILQFHGERNAYDEIDFDAMIIDTIDALKSYHHAVATQKRFDIPKSSHTILVVDKDLIPFPWESLPCMENQAVSRVPSLDYLRHAILEQRSTSHTTPHTAVSSDSESEAHGSRNAKTRPAGHHVQRSSGTWMLNPGGDLTNTQARFEDAIQALPSSWSRIVTTTPTESTFENALANSDILVYMGHGSGAQYIRSKTVRKMDKLRATVLLIGCSSARLTPAGAFEHYGTPRNYLLAGCPAVVGMLWDVTDREIDRYAAALMQNWGLLPHGTFDEGFFYDSHAKSPRRQYRDRGLVEGEMSLVEAVMTARSACTFRYLTAAAVVVYGIPVYIAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNM9</accession>
    <name>A0ABR3ZNM9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000382</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047404618" evidence="2">
        <location>
            <begin position="19"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="165" mass="16790" checksum="45A2182E64542655" modified="2025-10-08" version="1">MRFNYLLFTPALLAASSAVAVPADSDATSSTSSSYPIIPIYPTSRTSTSLQTVMVTKTIDVGSDTSSSSPPTPTTSDPNDYSVVPIEGLPPATTLTVTVLKSGTSVWTVTPTTETVPLGSGTGYLLPNSTMPVVVSAASRVSHAWSLSAVAIAVAGGVLAVATPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP84</accession>
    <name>A0ABR3ZP84_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA-directed RNA polymerase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rpc25</name>
        <name evidence="9" type="ORF">Cpir12675_000153</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04330">
        <property type="entry name" value="RNAP_III_Rpc25_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.120">
        <property type="entry name" value="RNA polymerase Rpb7-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013238">
        <property type="entry name" value="RNA_pol_III_Rbc25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036898">
        <property type="entry name" value="RNA_pol_Rpb7-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045113">
        <property type="entry name" value="Rpb7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005576">
        <property type="entry name" value="Rpb7-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II, III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709:SF1">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08292">
        <property type="entry name" value="RNA_pol_Rbc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03876">
        <property type="entry name" value="SHS2_Rpb7-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88798">
        <property type="entry name" value="N-terminal, heterodimerisation domain of RBP7 (RpoE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 9" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb7-like N-terminal" evidence="7">
        <location>
            <begin position="19"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase III subunit Rpc25" evidence="8">
        <location>
            <begin position="93"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU369086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="201" mass="22984" checksum="59FD644CCC86CDA1" modified="2025-10-08" version="1">MICRENESGRLDRETKVADLVQIAPDDFSKRSRDAIEDNINAKYANRVIQSIGLCICLYDLLWASEGLIGHGDGLVNVNVEFRIIVFRPFRGEVMLGRIRSSTPQGVYFQSSVLTNQTKHSNSDHQNQNWVWSYEDPDSGSVENLIMDNNEMVRFQVIDEEWHDQTPDGPSQVDDPNLRKAPYKINGSMAKEGLGICYWWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQW7</accession>
    <name>A0ABR3ZQW7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Plectin/eS10 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_000103</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic ribosomal protein eS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005326">
        <property type="entry name" value="Plectin_eS10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037447">
        <property type="entry name" value="Ribosomal_eS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12146">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12146:SF0">
        <property type="entry name" value="RIBOSOMAL PROTEIN S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03501">
        <property type="entry name" value="S10_plectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Plectin/eS10 N-terminal" evidence="7">
        <location>
            <begin position="3"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="92"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="107"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1902203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="160" mass="18383" checksum="E727ED8C2BCE0C6B" modified="2025-10-08" version="1">MLIPKADRKLIHEYLFREGVLVAPKDYNLDKHPDIDTKNLFVIKAMQSLNSKGFVKTQFSWQWYYYTLTVEGLDYLREWLHLPAEIVPTTHIKQQRPNAPPRGMLPDSERERRPFGRGRGDREGTYRRRDAGEGKEGAAPGEFAPQFRGGMGRGRAAPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRB2</accession>
    <name>A0ABR3ZRB2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_000134</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1902029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="109" mass="11999" checksum="2F11CE58C1B34CAC" modified="2025-10-08" version="1">MKAATNLDLDPSPKSFNAQEVGKLFNGTNHDVFDIYRPEDNIGITNGQNGMSDARYTPVRKDDAFAGVSCKCPPDTLMCELGDKAISRDLPLLIFDDNGFEYVAKSFAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YDM5</accession>
    <name>A0ABR3YDM5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UFSP1/2/DUB catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_006872</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000400">
        <property type="protein sequence ID" value="KAL1886065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012462">
        <property type="entry name" value="UFSP1/2_DUB_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07910">
        <property type="entry name" value="Peptidase_C78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UFSP1/2/DUB catalytic" evidence="3">
        <location>
            <begin position="112"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1886065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="341" mass="38757" checksum="15D1775A3149A5E7" modified="2025-10-08" version="1">MRIVRQLFSNNSSSSHSPRRHNSLSSRKGEPKTPSSTPVLTTPGPGPSTAKSEVRRLGISELGLFAYEKRMPGWLKSLLERRGTTALPGMIPSLAWHIDYNKSTSFAYLAHPGVQQVFKLRREGHFCGYRNIQTMASFVNAALCLGNEAFRGKLPTIFEIQDLIEKAWDAGINSHGREETGGIRNTRKYIGTSEAEAFFSFVGTPCSVRGFRNHSRTKASQNLLDWFLEYFSQNSNDLTRKVRFTDMPPVYLQNPRHSMVVIGIEKEVNGDLNLLVFDPKYHDDQDFTYLINKHSERATTEILSLYRRGIRYLGRHDQFEVLHFRHAELGIGQHPARGESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFX3</accession>
    <name>A0ABR3YFX3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_006829</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000387">
        <property type="protein sequence ID" value="KAL1886940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF85">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="81"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="146"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="56"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1886940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="867" mass="95966" checksum="D92B4F7631E03941" modified="2025-10-08" version="1">MSYITSPCINGNSPVQPSPGAASDMTIASPIMSSNASTPVQTPSGQHQATTPGNFTTTAHTSAASAGAGSGHGIKAPRILACVLCQHRKIKCDRNTPCSNCIKANATCTPSTPAPARKRRRPNQDLQERLARCEELLKTYYATSGSASSISTSSSTPLDCSTDTEPAPYPPKSTGFTQTGRVVMEDGTTRFTDNVLWSKFYDELSAMRQIINTQDSGIEDTSLGSESASPDELTELMMKDYSNMSLHDVQPEPVQMFRLWQVFLDRVNPLMKIIHVPTIQGYIVNAAGYSSTSLPANYRPLIFAIFTMAVYSLTDIECRQMLGVPREDAIKKYSHGVRTALSNVNFMQTYDIPILQGLFLYSISLSGKIDPHSHWIFGGICMRLCQKMGLHRDGEVLGLSPFETEMRRRIWWQIVLHDAGCALMTGMSVNVIPSFWDTKLPSNVNDADLFPGSTDPVEPREGPTEMGFSLISYELGRFMIRSHGMAGFETAIMGVDPESGRVLNKLDLELVHKYRAWVRDFKQKIQSQAEKYLDPTTGPMHEAASLLVDFIMKKLLEVLEPSEDMPQPDSDEFDFKDRMFRLGVLNLESHLELYQVMEGLNFLWFAKCHFSTDVMVMVAGRLMKCTTGPFIDRAWIAIDRTYYYHPELFDINKRSTHSLGTFLLKGWAGREAALVALGEASVPPRCILELRTRLPNHSYDSFSDEVISEPPIPSSLEAPMSSMPMRAMRGGHSNMQSANINNAAVSTNNPADSSGNINPNLINETLDPSIDQIIGGYLNVAQFDWDMWQDGSSNNPMNMNTANIANVNNRTPQTPMMHNFDNVLQPNSLPATIPGFGNIPVVHGIFMNSHDMEANPDGLKHPAPGPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH88</accession>
    <name>A0ABR3YH88_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein YTP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_006453</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000302">
        <property type="protein sequence ID" value="KAL1887694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018825">
        <property type="entry name" value="DUF2427"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018827">
        <property type="entry name" value="YTP1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31685">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_6G12730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31685:SF2">
        <property type="entry name" value="PROTEIN YTP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10348">
        <property type="entry name" value="DUF2427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10355">
        <property type="entry name" value="Ytp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="188"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="223"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="284"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="313"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2427" evidence="3">
        <location>
            <begin position="38"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Protein YTP1-like C-terminal" evidence="4">
        <location>
            <begin position="163"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="477" mass="52829" checksum="B990C945820E4F69" modified="2025-10-08" version="1">MASALSVRSVKAATGLIAFSKLVRHAAAFHDDSRIAEDETISSDPLDATLWLHIFVMMLSVGILYPIGMVLGMTKNRWHIPIQILATSLAAFGYLLGYFHKGRMFRASNVHTRFSGVIFIAIATQCVTGFYLWLPFGGQSIGGRIGSLIRPVHSILGKTFPVMAWVQMIFGGITTLGFCQGDHTGQCAAHFIMGGAFIGYATVMALFVAVGQRWLRRSGRSQEFFDSIIIAAFGCVNTFTEHHWGTAWVKNDWQHTTIGVIWWATGLVGIWLSTDRFGNPKRNFIPGFVLIVTGWGMSSHHQETMTSTMVHKMFGYCLMGAGVTRIIEICFVLRDQAALTDDGYSYSSFQYLPIFLLYLSGFLLMSATEEQMNLIEQSDMDHVSFIFITISMAALTFLFANFVIRLYDNLSSSIALPNDHQRIPQDDVEAERQAAHASEFELAGLTDDEDDDEHGFLAKNGGSKARPEATSTNTSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIC0</accession>
    <name>A0ABR3YIC0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PXA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_006351</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000286">
        <property type="protein sequence ID" value="KAL1887957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003114">
        <property type="entry name" value="Phox_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013937">
        <property type="entry name" value="Sorting_nexin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775:SF47">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 122 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08628">
        <property type="entry name" value="Nexin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02194">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00313">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51207">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="PXA" evidence="5">
        <location>
            <begin position="197"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="397"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="466"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="500"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="733"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="425"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="405"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="509"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="753"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="768"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="796"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="835"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="863"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="920"/>
            <end position="936"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1120" mass="121518" checksum="8DA086BB4E54408D" modified="2025-10-08" version="1">MADPEIETPQQVPIAVDSPSLGTSSEALLDEQGSPSTTTHNLPGDKVKRPETAAPTTPPSQNLVKEASLSLASKSESSKSDKPVDDIAATKAELIEKLTHFLATASPTTLSAVAVGIAATTYVILGRIGLILIGAVGGVALYASFETRTPQQSRKVRSEVGAELLQRLLDAGPRSATLRKDSQLDETAIISTLDDFSPQTREALNALIDAAIRDYVKSWYTPVVPNDRSFSLACRRALTNYIISISNHLSRKRPADVFLDFVTNSVSMIVVFISELSAAFAEIPSDSKISAADVVYGYLAENPDCNLANLLNQKQQTARLKTIAEDLLTYVDKPIFECDPTRIFLREILSSVILEKTLLSCSRPEWINSWIVSLLEAGESDFSQAIDVGMQAKPDAGRRAASVDADNSSETTSARASLDKDRRHAMTHKKKLSKADEEMEEAIQEMRRINQMIVNEQAIRSQSFELPGTPKHGSEPGVTCPSDGDPISDHNKAYSLVDTDSTSGEIVRTPTTPASPEPSASNAGITEEVPVSMASGNKQAFVNFDQMMPTMKDLTDEEVSKKVPLTLHNATINVHDDDTDNTWKILGKPNWEYLVQVEPASPHNPGWMVVRRYSDFESLHEILRRIATVSGASSFVEQHAILPSWKDHTRQTLRTELERYLRDSCWYQSLAESEGMKRFLDKDQGMPKAPEKSLFGWNAMGGMLDAVTDAPKGALQGSKAVVGGLFGSIGNLGKRQTQAATPSPEPPIHDPISSPAFSPPAAMDNRSRMSLTISPTGTPGRPEFPSPGMSLARASLDSTRSSIISVQPGKIAPMERRPSHQSIAMSPPPIPDENDAARRSHFDRWEKVPNSGRVGGSREHSRASSLAALRPPRSPSASSLEHLKLPPPPDQMTEDAEGIHLGLNKGDPTNPLVPSPLGRTASSSSIAKTHSKTSSVPLVPPTKPSKFGSNKTAAHKPLNQSETRVAVELVFAVFNELYTLSSAWNFRRTLLAAAKSFLLRPNNPSLIAIQEMMQTSVLDNNSSDTGIAAHIIKLRENAIPTVEEAMSAAGEMTDEEKEKLRAKARRLLIQSGVPGALKGVMGQGATSDAMGRLFDCLQMEEVARGLFFGILLQMVRILTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIC4</accession>
    <name>A0ABR3YIC4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Coatomer subunit zeta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">RET3</name>
        <name evidence="14" type="ORF">Cpir12675_006305</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 12">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 12">Golgi apparatus membrane</location>
            <topology evidence="1 12">Peripheral membrane protein</topology>
            <orientation evidence="1 12">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Cytoplasmic vesicle</location>
            <location evidence="12">COPI-coated vesicle membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000279">
        <property type="protein sequence ID" value="KAL1888083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14829">
        <property type="entry name" value="Zeta-COP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039652">
        <property type="entry name" value="Coatomer_zeta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11043:SF0">
        <property type="entry name" value="COATOMER SUBUNIT ZETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11043">
        <property type="entry name" value="ZETA-COAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 12" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 12" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="13">
        <location>
            <begin position="10"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU366053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1888083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="195" mass="21632" checksum="F36BD659971FBD36" modified="2025-10-08" version="1">MAPGMSLFSVNAVLVLNGEDGSRILTKYYNAPHQGTGAPTTSSPYADVKSQKAFEKGLFDKTTKQNNDIILYDNRVVLYKIDSDVIIYVVGSLDENEILLYNVILALRDSLHLLFKQSVDKRTILENYDLVALAIDEIVDDGIVLETDPTIIVHRVSKAPTQDVNIGRIDLSEQGVNNLAQLGRAKLTDWLRQGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIM7</accession>
    <name>A0ABR3YIM7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DSC E3 ubiquitin ligase complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_006350</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000285">
        <property type="protein sequence ID" value="KAL1887999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013861">
        <property type="entry name" value="TMEM115/Pdh1/Rbl19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066">
        <property type="entry name" value="RHOMBOID-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066:SF21">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08551">
        <property type="entry name" value="DUF1751"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01160">
        <property type="entry name" value="DUF1751"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="235"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="240"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1887999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="274" mass="30908" checksum="B7476A32A57655C8" modified="2025-10-08" version="1">MSFTNTPVTKFMVIGLVTSSIAASLFDAKHYFYILIDPHLWRYGQFWRLFTYQLSYSNSSEVLFACMTLYNMRIVERIWGSRKYASFVLVTSMFTAVIPPFVLAFFMKLVTGGAFNYLPAGPTPVIFSILAQYHLLVPHLYQYRVSATQSDASMATAPLTGVTLSDKSYRYVLAMQLAMLQMPGSILSAILGWIIGYAWKDFMPAALVKWRLPGWMVGLAHHKRGAEFEGLRRRLEGEDSTATATSSGAQRQNGEAGQRRTMRQQIMDNMGVNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIP2</accession>
    <name>A0ABR3YIP2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_006372</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000290">
        <property type="protein sequence ID" value="KAL1887885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="678"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="863"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="982"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="678"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="691"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="895"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="923"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="990"/>
            <end position="1007"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1887885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1007" mass="114075" checksum="1300602DF28E4375" modified="2025-10-08" version="1">MNQALSSCLDAPFIDPDRIYTVLIRHYASVLPFLHHHTFTQCFRNRKAPVGLQHSMSDVNDGNLMLVVALALACQSDTAICREASLYLEKVRSNSGPDSNMYSVQPLQPPHYYARVALDVLGTDNDGNSTVWSPGSMEQIQALVMLGMYEWLCKEGPENYPQGFAHWLSSGRGVSRSLDLFRERMQIETNTRTSEPNYRRQGWLRTLLSVTIMDRLLITAPTSEALLVETGQLPLAMCMPEHEFEGERVPNGYHKDGYGVDAVLVWLLRILDIFSEVNWFCSQGSRVRNNCPILELPPSQDADMAGRIPHQKQQQQQQSTSESHPRFLVLAAHVDKFRDSFPRHFVTNNIDNRTKAIVRDTMILENLCRLMLYRDRIPFIPLQNLATKGRHPHPKGREECDIYVISAAKEAYMSARKIIQIAHAANLDRASFRNVSATLPLSPIVVNAVWHAALASLHAHHFPHLDQTYALVSPDYQVVLNYGFTFNPRSQGSCGQAFVMLGYLASYWRSARRYRRIFRWAGAFLHLWRQAVIKALFDPPNIAPSALSSDQCLMRMRNDDFHSGFQEWEVFRHRYMTIGYEQGREKWEDDDLYPMFGVFDNAEEFPDYPDYEKYDLDMDMINAWTLVSSLVPQVSASVEVVCRVWDEVAHLDPLPGGMAAIFQGADVTTARLYSSDTATANSSGRNRISYNSGNTGSNRDGSNGSSGSSSSVPPLKWHPLLTIYPATRMWRWNEHFPADCHSLMLKNMWRRAIKVDANVAIGNYHFQDPSQLQTHTANFLPIVAWLPSFSSKPKTGVAGNLRNSESRTRLSSDISNPPFSGWTVELPTAVVAETCALVALDVLGKMTIRTSEFSPRSFGRAIVDDGVSQDGPTWQPPLPQAQQQMAPYHHHYGHHQQQQQQQQQQHQQQQQQQHQQRQHQHQPQHQPHPQSQPRHHYSNSFTMQDIALAPTPGNTIPTPVNSNGYFREGYHINGYYIDSSVTQGPAAPHSRQSVGRHSLGQNGSRPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJC5</accession>
    <name>A0ABR3YJC5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="10">PPIase</shortName>
            <ecNumber evidence="10">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">cyp6</name>
        <name evidence="14" type="ORF">Cpir12675_006174</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="10"/>
    <dbReference type="EMBL" id="JAWDJO010000262">
        <property type="protein sequence ID" value="KAL1888415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01921">
        <property type="entry name" value="cyclophilin_RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12235">
        <property type="entry name" value="RRM_PPIL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035542">
        <property type="entry name" value="CRIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035538">
        <property type="entry name" value="Cyclophilin_PPIL4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45843">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45843:SF1">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 10" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="12">
        <location>
            <begin position="6"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="13">
        <location>
            <begin position="257"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="346"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="364"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="403"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1888415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="507" mass="58685" checksum="811E19B6DD5D71C4" modified="2025-10-08" version="1">MSVLIETSAGDIVIDLLVDYAPKLCENFLKLCKVKYYNFSPVHSIQKNFSFQTGDPLGPLSAESDGGTSIFGLLSGNPAQKSFPVDFNPKLKHAERGTVSMVTVPAEGGRNGADEIRLAGSQFIVTLGDETDFLDGKAAIFGKVVEGFDVLEKINGAFTDSKGHPLVDIRMLHTIILDDPFPDPEGLTDREPPESPAPTKAQLATVRIESEDALKDDENIDEEEREKRRREREARAQALTLEMMGDLPFADVKPPENVLFVCKLNPVTTDEDLSLIFSRFGRIVSCEVIRDKNTGDSLQYAFIEFDEKEACERAYFKMLDVLIDDRRIHVDFSQSVSKLSDVWRDGTNKKRQQRRGGGWGGVNELEKRSQYKNEEKYTRTGDSYGMVYGTEEMKKRMRSRSPRGSDQDRDRERKRDGDRPQERERDLDRDRNYQARDRDRDRDRDMDRDRHPHHDRRRNGDGVRDRHPEKDRDRERDRDRDRNSDRDRPRYRDEDDRDRRRRKGDRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJN9</accession>
    <name>A0ABR3YJN9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box protein YLR352W</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006347</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000285">
        <property type="protein sequence ID" value="KAL1887996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="123"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="146"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="739" mass="82160" checksum="EBF62B4EAB5E5C34" modified="2025-10-08" version="1">MAASSLGISSPSPSIRSAFFEAGAHERHSAPFSTQTQNGQQCLSSQHDQKHQQHQQTESLCNLTQQAFDDDAAAQSRSPPLDGTLSRGSFSSVREDELGHAQSFTSSKTSAFTYAVESALVDSPNSSASSSPIPSRPAVRPPPTLSSPTLAPPTTNCASLFPEDKGLHRSASGIAVNTNTNKIDAAGTMWQPTDTFRGWKQINLRGKYASRSFSDLQLLNMMWNLPSIPAVEDASAKPGAGHSRLEILPIELLGAIIDLLYVETPTKGLTKRNGDLIAVLNTSHTLHVATMHTLYRKITIPHSKIFRKFLTAIQRDPFLGTIVQRLDFNHFNPNMLFSTGGERSQAQNLTKDTLLQCLELTPNVREFLAQEHILEDLSAQVVNKLFFGLEKLQAVDFAGCSNRAFKLVWDEVLQDSEKWTKALSIKRMSFHKCMILPPVVYETVFPCLDRLTHLDVTGCRVTDRALMLIPQTARIAHLNLSKCAQLTADCVLQFIEKHPSVRETLVVLNVATDATSHQMFNEDQVSKLLTILPPTLKSLNLKGSRMGPQHIKQLKSVVAQIEELGIGRGVDIRQVGQLIFPEKKKVDQSQDRGSAAWDIGSDSGDSDDKSDLVGIGHSLRYIDVSDMYSTTDLDYLFDKNCRLLDSVSYPLQVIEVSENVAKRMRASYKAVRSHGWAISEEGARCWLVRRNEWQTKSMRHEEAFRWWKMGATYWGTRKIPVADCEVGGMYGSFMFARKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJQ3</accession>
    <name>A0ABR3YJQ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Endopolyphosphatase</fullName>
            <ecNumber evidence="3">3.6.1.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">PPN1</name>
        <name evidence="15" type="ORF">Cpir12675_006328</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the endopolyphosphatase PPN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.10" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000283">
        <property type="protein sequence ID" value="KAL1888011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000298">
        <property type="term" value="F:endopolyphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012358">
        <property type="entry name" value="EndopolyPtase_N1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10340:SF55">
        <property type="entry name" value="ENDOPOLYPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10340">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF027093">
        <property type="entry name" value="EndopolyPtase_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0926">Vacuole</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047049794" description="Endopolyphosphatase" evidence="13">
        <location>
            <begin position="32"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="14">
        <location>
            <begin position="67"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="494"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="559"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="664"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="703"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="502"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="523"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="567"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="589"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="703"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="729"/>
            <end position="740"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1888011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="765" mass="86999" checksum="915E4645D550C8FE" modified="2025-10-08" version="1">MQSQSRPRLWPRSRWLQSYITALLLSQQASALAIGKTPQLQHVLPLHETARKNLQENGAGGSRLHGRFLHITDFHPDVFYKAHTSTAEDIACHRSSGPAGYYGAETSDCDSPVHLVDSVLAWIDENVKDTVDFVIWTGDSARHDSDEEIPRNASQVLGTNKMMVKKITKLFSDDQGKLTIPIIPSLGNNDILPHNILMPAPSEWLRTYTDVWEAFIPNSQRHSFEFGGWFYVEAIPNKLAVFSVNTLYLFDRNAGVDDCVNPSEPGFMHMEWLRIQLTQMRARGVKAILTGHVPPARTAGKKNWDETCWQKYNLWLVQFRDVIVGSIYGHMNIDHFLLHDSNDLDILQADDVLQDTSEEASSQINQDEQDTVHDEAASIYASANYLVDLRRLWSKLPDPSAAINAADSEAEFSASEKRPWKGLGNKHAERYHLSLVSPSIVPNYFPTIRILSYNTEGLDGPLWRDVENVIIKDDSPDEISTMRLQALENEIEMANKKMNDKKGKKNKKKGKKGPHKDPHLVIPDPPAKGTPPGPGYKMQTLSWLGYVQYYANLTHLNNNIKSSTPEKKKKDKKKPTKGNSVELRSLPETETEVEDDLEFDGEVDQTKWREGPHKNKKLHKNPKHLPFKFDFEYSTFTDKVYKLKDLTVKSYVKLAYRLANHKPRKGGKALDPLPAETEVEESPLEFLESDSAESIYQRMTEVEEEIDEASVDEDDYEDTESDAGSSALRKGKKSKDKKKKNKVWRQFLEFAFVKTLDKKKIDSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKP5</accession>
    <name>A0ABR3YKP5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UV excision repair protein RAD23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RAD23</name>
        <name evidence="9" type="ORF">Cpir12675_006212</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the RAD23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000265">
        <property type="protein sequence ID" value="KAL1888356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14281">
        <property type="entry name" value="UBA2_Rad23_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01805">
        <property type="entry name" value="Ubl_Rad23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.540">
        <property type="entry name" value="XPC-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004806">
        <property type="entry name" value="Rad23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006636">
        <property type="entry name" value="STI1_HS-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015360">
        <property type="entry name" value="XPC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036353">
        <property type="entry name" value="XPC-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00601">
        <property type="entry name" value="rad23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10621">
        <property type="entry name" value="UV EXCISION REPAIR PROTEIN RAD23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10621:SF0">
        <property type="entry name" value="UV EXCISION REPAIR PROTEIN RAD23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09280">
        <property type="entry name" value="XPC-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01839">
        <property type="entry name" value="RAD23PROTEIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00727">
        <property type="entry name" value="STI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101238">
        <property type="entry name" value="XPC-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3 5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="8">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="7">
        <location>
            <begin position="144"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="7">
        <location>
            <begin position="333"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="97"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="193"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="194"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="208"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1888356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="384" mass="40682" checksum="D6F1BABD872724B0" modified="2025-10-08" version="1">MKITFKDLKQQKFVLEVEPTISVADLKQAISNDKGWDPKHQKLIYSGKILKDDDKVETYNIEEKGFVVCMVNKPKEPKPASVSAAKTAKVTVAVTPGPASVSTPAAPAAQRSSAASAGAPATPTPAFRTAPPSFTNPSAMAVGAANQEAIENMLAMGFERCMIEAAMRAAFNNPDRAVEYLLNGIPDSAVRPTPAEAAAPEAAAAPEAPEDTNMTDDNTDNVNLFDLAAQARQGGGQGGQDSAAVAAAAAAAGGAGGFGNLDFLRNNTQFQQLRQVVQQQPQMLEQILQTLGAGNPQLAHLIANNPEQFLNLLGEDVDDDAPLPPGAQAIQVTPDERDAIERLCRLGFDINQAMTAYFACDKNEELAANFLFDQPEDDDQAPDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKQ7</accession>
    <name>A0ABR3YKQ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal protein bL31m N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000241">
        <property type="protein sequence ID" value="KAL1888856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034600">
        <property type="entry name" value="Ribosomal_bL31m"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048874">
        <property type="entry name" value="Ribosomal_bL31m_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28174">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L36, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28174:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL31M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21492">
        <property type="entry name" value="bL31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal protein bL31m N-terminal" evidence="2">
        <location>
            <begin position="55"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="175" mass="19748" checksum="DA8F07CE1FF3843D" modified="2025-10-08" version="1">MRSQLQLARNALLQTSRTPTTTCTTVTFTISETLSQSSAQTTVLHQVRHARLIRRPRRPYTFTQMIQLSDGSTFTARTTSPQPLFRSTKDTRNHPLWQPSDRTLKNVELDEAGKLAAFRDRFGRGFDLQKDPSEEGYNEADVEFDLGDLISEYAVAEEPTKPAKSKEDKGKGGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLG5</accession>
    <name>A0ABR3YLG5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_005889</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000227">
        <property type="protein sequence ID" value="KAL1889179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF12">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G06440)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="337"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="374"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="415"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="443"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="474"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="511"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="109"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="555"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="588" mass="64534" checksum="9CD2A0E84F682EBB" modified="2025-10-08" version="1">MQPTSEKQAPSGPPANICPSDLESQTLSIIPTSTSRESSESNHLSPLPHALTPISETDVERTTRELLDHVQTATSLASVASRLPEFEVTLDENDPENPRNWPIWYRTWTMVVLSFSTWLIVLYSTSYTASIPGFVAEFDTTTTTATLGVTTYLLGLAVGTLVLAPLSEIYGRHLLYVVGMAAASLLIIPCATAQSLTTLIVTRFFGALFGAAFIANAPGSIVDISHEETRALVMSLWSIGPLNGPSTGPLIGGFLYQYLGWRMAAWIVMGANGIAVICLLTLKETYAPAILKRKTARMRKEMDDPRYWCKYDQRVSTIHLLKLNLSRPFILSATEPILWFFNIWISLIYGILYLCFVAYPIVFRQYRGWDAAHTGMSFLGIASGVMIVIACEPVFRHIINSQPKDRVTGRTVPEATAVVMTIGAFLTPIGQLAFSWTCLPVSIHWALPICSGIIFGAGNTISFIYGLNYIANAYGIFAASALAGNAVIRSIFGGTLPLIGPIMYEKLTPQWAGTLLGLLEIALIPIPIVFWRYGARIRAKSPILMQMREEEAKAELKRAKREGRKTENMKPTADTRVGPVSSEKAVVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM15</accession>
    <name>A0ABR3YM15_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000224">
        <property type="protein sequence ID" value="KAL1889233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="61" mass="6272" checksum="B873C2C6586F0DB1" modified="2025-10-08" version="1" fragment="single">QLSQDALDQVLELDPSGSSPPLPNSASARQRVPSNGQEIPDWTGDIAGSSTTLQVLGSPGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM50</accession>
    <name>A0ABR3YM50_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpl8</name>
        <name evidence="6" type="ORF">Cpir12675_006004</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000240">
        <property type="protein sequence ID" value="KAL1888915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004037">
        <property type="entry name" value="Ribosomal_eL8-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018492">
        <property type="entry name" value="Ribosomal_eL8/Nhp2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001921">
        <property type="entry name" value="Ribosomal_eL8_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00881">
        <property type="entry name" value="L7ARS6FAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00882">
        <property type="entry name" value="RIBOSOMALL7A"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01082">
        <property type="entry name" value="RIBOSOMAL_L7AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="5">
        <location>
            <begin position="122"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1888915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="263" mass="29433" checksum="67A2EB1D06685CDD" modified="2025-10-08" version="1">MAPPKSGKKVAPAPFGVKSSGVKKTVKNPLIEKRPRNYGIGQDIQPKRNVSRMMKWPEYVRLQRQKKVLSIRLKVPPALAQFQQVLDRNTAAQAFKLLNKYRPETASEKKERLLKEATAIKEGKKKEDVSKKPYVVKYGLNHVVGLIENKKASLVLIPNDVDPIELVVFLPALCRKMGIPYAIIKGKARLGTVVHKKTAAVLALTEVRAEDKNELSKLISAVKEGYLEKNEAARKQWGGGIMGDKAVKRIEKKRKALENSLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNF7</accession>
    <name>A0ABR3YNF7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein HOL1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_005795</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000217">
        <property type="protein sequence ID" value="KAL1889395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF29">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G06680)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="359"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="397"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="440"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="477"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="508"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="539"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="266"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="269"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="290"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="306"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="580" mass="65279" checksum="E894694064396947" modified="2025-10-08" version="1">MGWGILEPRQKGHVPGTTRYYDDPNQPGYIANQNNGRLKTVMKNGDHLILIPQPSDDPNDPLNWPLWKRDLITFILSMSAIFATAQGSILAANTIVITIEIKRKFTEVALLTGYFLMGCGAAAVFFVPSGRVWGKRHAFIVGLVILVASSAWASTVGSNYESFVWARIIQGVGCAPFETLVNAAVGDLYFVHERGIRMAFTNLAVFGGAFFTPIVVGKMTMTMGWKWTFIFSAIFCAACFPLVFFWCPETAYRRNSRLNTDMACDTDDTQSTGIPGTRDSQGNAFEMSPRSDSNSIGETGQFLPSSKEDGHRTEPHVEQSGFIRKKTFRESLALFDGRKTDDNYLVLLLRPFPLLFHPAFLWTCLIQGTMIGWTVFIGVIIAMIFQGPPYWWQEDKAGYTYLGPFLGAVLGFFIAAFLSDWMVRYMTKRNNGIYEPEFRILLIIPMFIVGEIGLFGFGITASQIITGESVWQEPVVFFGLEVCAMVIGTVSSSLYIVDAYRDLAIEGFTISIIFKNLFSFFLTWYAFDWVTMGIGTKKTMFILASVQIFVCLTSIPMYIYGKRIRAYFHHHDMLKKLRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNK1</accession>
    <name>A0ABR3YNK1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-dehydrosphinganine reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">TSC10_2</name>
        <name evidence="2" type="ORF">Cpir12675_005587</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000199">
        <property type="protein sequence ID" value="KAL1889941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022190">
        <property type="entry name" value="DUF3716"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12511">
        <property type="entry name" value="DUF3716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="482" mass="51400" checksum="0547B0C1272DDA02" modified="2025-10-08" version="1">MSMRAGAATTAPVRSPVRNRATSIATSTTAVTGNNKITKPSPPARRHPHSHPHTHGRPSPLLEDTLERIANGEDGLDDTVNVNVSVSTTASTDPVSITTEAQASIDASAALVHHEQQQQQHQHQQAQAQQQHQHQHHDLAAVAAEAADTQRQLQNLSAAANLLANSANDPTIHPELQRLSAVDNQSSIATAARTLDQAVQDQLQDMQADNSIGAAAAASLVMDTTSGSTNENNFETAEILARASGYTNLDIESAASTLSKRLAPQPGRRIAVQRRQDQTLNLGRRSNVEALLAHIAGNEAASACKNCHKGHGPWNTCVVVEGQMCGSCANCWYNASGSRCSFHETNNPQAHQPALHNNRASAFHSQAAASRLPQTSQGLLLQPNAAFAATPATQAQGIVAADFAALHSGLDDEATTLIEKAFREVREGSARARHLLAIDAAAKQLALRMHEYDVFLQTPEGAQMRQEELEALRSPDPASMNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNN7</accession>
    <name>A0ABR3YNN7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cation/H+ exchanger transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_005774</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000215">
        <property type="protein sequence ID" value="KAL1889466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050794">
        <property type="entry name" value="CPA2_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32468">
        <property type="entry name" value="CATION/H + ANTIPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32468:SF0">
        <property type="entry name" value="K(+)_H(+) ANTIPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="183"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="254"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="366"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="9">
        <location>
            <begin position="41"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="498"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="660"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="508"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1889466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="870" mass="93239" checksum="D7D96DC76404BF55" modified="2025-10-08" version="1">MSITDKIPGSLVRRAARAQAGILEGMDPTDYDPSNPIILFIIQPRVIAEVIGGIVLGPSVMMRIPNFKETIFPTESMPVLNNVANLGLVIFLFLVALEIDLRKFRQNWRLAAGVGVASMLLPFGLGVAIAWGLFHEFRSGTNLEDIGFGTYALFIGTALAITAFPVLCRILTELKLLHANVGVTALAAGVANDVTGWILLALCVALANNSSGLAALWALLCTIGWTLFLTLIVRPIFIWYLRKTGSLQNGPTQGIVALTMLLVLASAFFTAIIGVHAIFGAFLVGVICPHDGGFAVKMTEKIEDLISVLFLPLYFALSGLNTDLGLLNSGIAWAYVVGVLAVAFTGKIVGGTLAARLFKLEWRESLAIGVLMSCKGLVELIVLNIGLQAKILNEQTFTIFVVMAVITTVSTTPLTKLLYPPSYQRAIEGWRRGETDKKGRPLLQSGPSSQANASSALRTDMVHRLMVHLRLDTLSSLFTFVSLLEIEDVKTNGVDAGNEAKAGHADPANSNIETPGESTDVQTHRHLEVHGLRLLELTDRTSSVMQSTEGEEYGVSDPVVTAFSTFSRLNEVAAAGRVAIVPASSFSETLVHHASSISSDFVIIPWSQRGSLTEDQGSSMPSEISSFQGRGYSEFVQETLRHAPCPTAIFMDKGFGGGNKGLPTRPPISRTTSVHSTRTRKDPIALPVKDKSHVVFFPFFGGADDRVALRFVMQLSKKANVTATIAHFKLTGEESRSVDGQVEKTTAYEAHASSNSSQHSSSVDDHYLLSSLQSNLVSLGGGRVAFTEIPVTRQNAIAIALQTAQTIVGQNPRNAGDLIIVGRSHLCLDDGATDIGDELKSTLGQAASSLLGAHANASVLVVQDTRLTSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNZ7</accession>
    <name>A0ABR3YNZ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Letm1 RBD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_005545</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000195">
        <property type="protein sequence ID" value="KAL1890094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033122">
        <property type="entry name" value="LETM1-like_RBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07766">
        <property type="entry name" value="LETM1_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51758">
        <property type="entry name" value="LETM1_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Letm1 RBD" evidence="3">
        <location>
            <begin position="173"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="383" mass="41603" checksum="54979B0D488B6392" modified="2025-10-08" version="1">MKLPHQFGAIRASALPFSLWLTAKSIHSSLRIKHTSLAGLRLASSMPTARKTTGGLAVVSSSTAVAKILAYPESRVNPPLTTLPPVLSLPEKTNVTSKASYYVGMAKGYLAFYKTGLKSVFAAKKMLNKRRAAASPGPMPSPRAVTTAFATSGMLSANITRADWLFARRVQHDTIRIPIFGLILLVCGELTPLIALYIQGIMPYTCRLPTQLHKDMAAAEARRAASFVRLAPVLPTGLCGAYLPSNAGALARRHILSSLHLMPALLDRIAGELLAPLYWRLKGIARLSFLAVDDSLLRRDGATEALSDQELKLACVERGLAVTDVPLQVMRDQLRRWLVLSQTIGPAEQRAEEAQKRIAALLTTRPDKWNGMSPGFAVYTESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPB1</accession>
    <name>A0ABR3YPB1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pre-mRNA-splicing factor cwf18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000190">
        <property type="protein sequence ID" value="KAL1890199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013169">
        <property type="entry name" value="mRNA_splic_Cwf18-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31551:SF1">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31551">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08315">
        <property type="entry name" value="cwf18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="209" mass="22834" checksum="DD7DCB22E6DCC3C3" modified="2025-10-08" version="1">MSSNLGAAADARKARLAQLRNLKRKLPADEVAAPESNRTSPLDTPSASGSTIPDVAALRLSGRNYDAATRGPKLGFENAPNEALDGPTLEEKAAEIAAQVRETAQKDAQESAASIDLFKLQPKKPNWDLKRDLDKRLETLNVKTDNAISRLVRKRIMESSNAARGKSKGTAAEGDQETMIMDGTELVEGLRVREQEIEEERRERAELDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPI3</accession>
    <name>A0ABR3YPI3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_005625</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000202">
        <property type="protein sequence ID" value="KAL1889857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052256">
        <property type="entry name" value="E3_ubiquitin-ligase_CHFR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16079:SF4">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE CHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16079">
        <property type="entry name" value="UBIQUITIN LIGASE PROTEIN CHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="9"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="89"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="299"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="497"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="561"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="599"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="89"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="167"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="253"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="307"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="325"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="378"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="389"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="405"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="450"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="497"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="534"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="561"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="600"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1036" mass="115751" checksum="CB1CBFC616AEDE59" modified="2025-10-08" version="1">MDLEKELTCSICTELLFQPLTLLDCLHTFCGACLKEWFAFQASAAERSPLPLPPAGTPLFTCPACRAAVRDTKHNATVATLLDMFTTAHPERDRGAAEKDELREKYQPGEKVLPDVDLRGRSEQERADAEEDRRLMEQVRQMSLNEIGVTRPSNVPTPGRPQHRRRRTDEGNSDTERQTHRRPVSHDGRDRPRRDGSAARANLRNNGDHLQPVDFRGSSSSSDGGHRRRSVDQRRGEETNASQGAINRDEGEASSTTSRQVEHQSSLRSLIGTTGMSEGDIAREVEELARQIQQEGLLDGLDLDNLDPSHHDELSRRIAQAYQRRQREKERDRERERGREREREREREHQRWSEARRIRADDQSDVSRPPRSSSAQRYHSRDHSRARRGTTTTTVSAAPTSSSQHESHRNSEDRSRPPPAPSAGHYLEIDTDRRRRRAASTGHSIASAVRSATDSISGTASANSQAARSQVDLAVRAPINDNRAARSQTDLSLHTVTTNSCAARSQNDPSLRTTNPQTVTTEAITMSPRDRSDTQLFSSPPQTSDTGRSFANRLPQVTVASAPQTPAVSSSGIAPAPANPPSSRWNASQMAVELPAELPVNSNQPVPRNTLASSQGAGHHRSVSQPANITTAFTTILAPEPSISCSRCEKPHIEYELHYNCGKCSSGTWNICLLCYRKGRGCLHWLGFGYTAWRKWDRLRQAGDADLEKPHMLTVGRYRRPQNNGQNYGADSIEERFESGCFCARCYQRTNECYWRCEICNDGDWGYCNSCVGLGRRCNHPLLPLTYQPTSNSGEMSANLPRWAGLLTSPTAANIGSFRPLSFKPRCNICVKPILPTHRRLHCFQCVGETAIDLEGSYEGDYDLCMSCYAFLASSGNISQQNGSAGWRRCPKGHRMVIETYLEGNGGERRVTIEDVVGGSLMKLEDYSEERYLRWTSKENGRLVSRKVSRNVACDVPTSELENDVFSVPREQDLGSKYVAGWPWFGQHKQADDELYFPRGASLKEVEIAGESWLFGAFMDRSGLFPAGYAKMIRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPL7</accession>
    <name>A0ABR3YPL7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_005640</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000203">
        <property type="protein sequence ID" value="KAL1889843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18497">
        <property type="entry name" value="BACK_ABTB1_BPOZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044515">
        <property type="entry name" value="ABTB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46231">
        <property type="entry name" value="ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46231:SF1">
        <property type="entry name" value="ANKYRIN REPEAT AND BTB_POZ DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="4">
        <location>
            <begin position="165"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="4">
        <location>
            <begin position="384"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1889843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="657" mass="74928" checksum="9F12A20C0E0F3E1C" modified="2025-10-08" version="1">MTATDSDNDEISPQRFIELQNTILDIAKNNNKLRKLPVEDRFAGTPLNKSPKFEALLEACRRGDLKTCHELIISGVNINARDRYDYTPLILASICGHFELVKLLLDYGALAERNTFQGERCIYGALTLKIRNLLLSYDFSKATDPLREWSGHINSIRSGQPPGTPDFRLRIKDDSGASCGVHRMILAARSPFFRDMLAKDPGLTSWTAQGVDVDEECLHTVHKFLYLEQIPDSELSLRNNIKSPAASRILEGCKKLAQEFDLPGLEELLDARGQLNVARKAHQQQVNLAQVQMNEFFAEFIMKQKMVASENEVDSIQWSYANHALADVLLKVEYVDESLETGTEAEFELNNQLSACEVSIRDTNLTEVLPRKEDRQQLRKYIIYPAHKAILARSPYFKHMFTSGFMEGQSSQSLHMVSMTCAPVTLEVILANLYFEKGEISLPYSLDLLYTADEILLEKLVNKAALTISSQGMVESNVWEDRTHKLDPKKKSRGGRSEAPDGIDIYEIIHAAWDLGVQRLEDFAARFFSSRLEDYIDDPEFLAIIRKSAERVKDRQATDTIELLDDIRHHLKDRFRMRFQDVSLVMERDPTQAQHIQAEQTMAKTKTAIRTLSGEMAEDEFAADDMNYEFLMDRLDKLLEKTNEAVYKDKINRQNVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPW5</accession>
    <name>A0ABR3YPW5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PRE9</name>
        <name evidence="7" type="ORF">Cpir12675_005422</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000185">
        <property type="protein sequence ID" value="KAL1890376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03752">
        <property type="entry name" value="proteasome_alpha_type_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="6">
        <location>
            <begin position="5"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1890376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="251" mass="27887" checksum="BF2DA2A13786B71B" modified="2025-10-08" version="1">MARRYDSRTTIFSPEGRLYQVEYALEAISHAGTAIGILAKDGIVLAAERKVTSKLLEQDTSAEKLYILNDNMICAVAGMTADANILITYARQIAQRYLLTYNEDIPCEQLVRRLCDVKQGYTQHGGLRPFGVSFIYAGWDPKRQFQLYHSNPSGNYGGWKATSAGANHASAQSLLKQDYKEDCTLKEACAMAVKVLSKTMDSTKLSSEKIEFATVGQTEDGKIYHKLWSAEEITALLKEHGLAKEEASEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPW9</accession>
    <name>A0ABR3YPW9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000200">
        <property type="protein sequence ID" value="KAL1889933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="1">
        <location>
            <begin position="75"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="535" mass="59939" checksum="F7183E2C747E9D88" modified="2025-10-08" version="1">MAIKNNMSLTDMRKAWAMSVKTTDSAPEAVMSVSGSNDTVSPDQTMVDMSMLSNETTLVGSPACSNTQKQSGNELTCMVCNVSPTDKVHLDAHLNSKAHQNAVNQLRVASDNNASSRQKLESFIAWCEYHHVELPSLVLDMSKQNRNIRGRRDGYLNSAHYVTEQARRFTAADPYRGMYYDGLPSMSEAFNPHRVPQYLQGPTYFPQIQPHLASIPPDQPIESIERDEEEVKDRGSDNGIEYRPYGRQHVPHRASNKKFTIHGKYSATIVKVKRGFNTFAGVKDREPPQLKGLCLPGIGIWDSATPSQRRYRNQRKGNEAVKRIELLASMVKTTEEVWNLAMQKERERHIYDIPSSPNSPILAQPMVRPPPCVMEPAAFLLSAIDGRTNAKDPGSNLALDGHCAQDEYRPEDPILNKQMPMTKTGEAECHQSSIMTSKEQESSINYSSHHQGLSMFNNNSVLPPLHPSPASLAYHTIDQNMINNLSLPSVLYQVPGNNMQDSSKEKEPEPKISYHEMLPSFLYNLASLKNDESSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ07</accession>
    <name>A0ABR3YQ07_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcriptional adapter 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ADA2</name>
        <name evidence="14" type="ORF">Cpir12675_005433</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000185">
        <property type="protein sequence ID" value="KAL1890386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02335">
        <property type="entry name" value="ZZ_ADA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041983">
        <property type="entry name" value="ADA2-like_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016827">
        <property type="entry name" value="Ada2/TADA2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055141">
        <property type="entry name" value="TADA2A_B-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12374:SF20">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 2-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12374">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22941">
        <property type="entry name" value="TADA2A-like_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25299">
        <property type="entry name" value="ZZ_ADA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF025024">
        <property type="entry name" value="Transcriptional_adaptor_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50934">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01357">
        <property type="entry name" value="ZF_ZZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ZZ-type" evidence="11">
        <location>
            <begin position="16"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="13">
        <location>
            <begin position="77"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="10">
        <location>
            <begin position="82"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="SWIRM" evidence="12">
        <location>
            <begin position="473"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="156"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="156"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="170"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR025024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1890386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="561" mass="62346" checksum="E16D03A3B921C78A" modified="2025-10-08" version="1">MGVIRKKTAVRGGEGGVKYVCDVCSVDITSTVRIRCAHSACNEYDLCVQCFAKGESSDLHKPESHPYRVIEQNSFPIFSEDWGADEELLLLEGCETYGLGSWADIADHIGGYRTKDEVREHYLTVYIDSPRFPLPKRCSPYDNELATRVSREEFQARKKRRIEDRRNEAKAAAAPLPKTKPTASVPSCHEIQGYMPGRLEFETEYVNEAEEAVQSMQFDPGDGFNPRTGELEPEMDLKLTVMDIYNNRLTQRVQRKKVIFEHNLLDYRENIKHEKKRTKEEKDILLKAKPFARMMNHNDYENFCQGLLDELNMRQAIAQLQEWRSMRIGDLKSGEKFEVEKQQRIQKATPMGSMDRDRLAGLQRTKGQPPPEPPSGAALLIAPEMPARMSLPPAGTGRKAAELADNQAALANGDAVDSHSNANASANGANGVVNGSAANGAPNGTASHGASNGAPAINGTTTMAPRLKYVAPPISGMQALSLTHENAPDLHLLTPEEVKLCEVIRMQPKPYLMAKEQLLKEALKGNGMLKKKQAKEIVHLDSQKVGRIFDLMIHSGWIGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ58</accession>
    <name>A0ABR3YQ58_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">2-(3-amino-3-carboxypropyl)histidine synthase subunit 1</fullName>
            <ecNumber evidence="4">2.5.1.108</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Diphthamide biosynthesis protein 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Diphtheria toxin resistance protein 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">DPH1</name>
        <name evidence="16" type="ORF">Cpir12675_005572</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-histidyl-[translation elongation factor 2] + S-adenosyl-L-methionine = 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36783"/>
            <dbReference type="Rhea" id="RHEA-COMP:9748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9749"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73995"/>
            <dbReference type="EC" id="2.5.1.108"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DPH1/DPH2 family. DPH1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.108" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000198">
        <property type="protein sequence ID" value="KAL1890006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090560">
        <property type="term" value="F:2-(3-amino-3-carboxypropyl)histidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11840">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11850">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11860">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016435">
        <property type="entry name" value="DPH1/DPH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042263">
        <property type="entry name" value="DPH1/DPH2_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042264">
        <property type="entry name" value="DPH1/DPH2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042265">
        <property type="entry name" value="DPH1/DPH2_3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00322">
        <property type="entry name" value="diphth2_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762:SF1">
        <property type="entry name" value="2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762">
        <property type="entry name" value="DIPHTHAMIDE BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01866">
        <property type="entry name" value="Diphthamide_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00032">
        <property type="entry name" value="Radical_SAM_3-amino-3-carboxyp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 16" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="23"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="54"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1890006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="445" mass="49232" checksum="DA910146869BA6BA" modified="2025-10-08" version="1">MEADRAETDIGIAADIEALSLAQETADDAPMTQTETTTKQPKKRFVGRRAATEAQANGAVSTSTEVGGKPPRLLNQVPPEILQNKALNDAIALLPSNYSFEIHKTVHRIHTLNAKKVALQFPEGLLLFATTISDILTEFCPGIETLIMGDVTYGACCIDDYTARALGCDLLVHYAHSCLVPVDVTKIKTLYVFVDITIDTSHFIESLKRNFVSGKTIALVGTIQFNATIHGVRASLEKEGFSVVVPQIAPLSKGEILGCTSPHMKQEDNVDMILYLGDGRFHLESMMIHNPTIPAYRYDPYSRKLTREVYEHTEMQGLRRAAIKEAKVARKWGLILGSLGRQGNPHTMAKIERRLTERGIPFVNLLLSEIFPGKLAMMNDVECWVQVACPRLSIDWGYAFPKPLLSPYEALIALEELEDWGSGPYPMDFYARDGLARAKPMTLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR32</accession>
    <name>A0ABR3YR32_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_005236</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000171">
        <property type="protein sequence ID" value="KAL1890811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051948">
        <property type="entry name" value="Hsp70_co-chaperone_J-domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44360">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44360:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="61"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="344" mass="38096" checksum="8BAE31CC88022B7F" modified="2025-10-08" version="1">MMSGWIQSLWYTLTIRAGSPHPAPGSPRHRLHRRIIQTLVISTYLLYTILEADYEISRTGNFYTALGVTPAASDREIKSRFRRLAAIHHPDKSSVGPTDGPGSADFFIMLKTAVDTLTDPAKRFAYDRFGDGVHEWKHCTTVYDYLQRGAMDRLVPHYLGAAMLLYILGFFGLMENGRLWRWLLMATMSVAEITLLTRPTLPRIFANVMNPVLALVAGRAPYVQFQVIALLRRLSITVAIALAQLGPVLFPNDGSTSKAEVALAQGLGRLEGVAGGLDKEITAVMNVEFAPFKDDASMITALKGQIKDWLVQNTIRSDPMVVDAMGTSLRRRRPDAPHGARGTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRY2</accession>
    <name>A0ABR3YRY2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Meiotically up-regulated protein 157</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005298</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000177">
        <property type="protein sequence ID" value="KAL1890666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008313">
        <property type="entry name" value="GH125"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31047:SF1">
        <property type="entry name" value="DUF1237 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31047">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 157 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06824">
        <property type="entry name" value="Glyco_hydro_125"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01149">
        <property type="entry name" value="DUF1237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="612" mass="67605" checksum="72FCDE444CD75E06" modified="2025-10-08" version="1">MVILRSRGSFRFILIAITITGILTFIWMSNAANLNILPIPYQNEAGTAGSVETPEANHPPHHSTTPQAFESKLPYQAEAASSSIPLNHPPSPIDTPSAVPVKYGWQDISQGCPHYTRYSSRAHLPKSQGKLGLGFQRPEAQCRTFVSKEVENEIDRIRQVMTDPDLFRLFENTFPSTIDTCVKWMGVSADNPDEELAFIITGDIDAMWLRDSANQLQVYRDIITSRTDELAALFRGAINMQARYIMKEPYCNAFQAPPESNIGAGLGGGGSTVYPFFDRKLVFTCNFELDSFGAFLQLSQDYFQATGDIEFFGKFHWIDAIKSIMKTAADMSASTYDEDGKPRPLPYKFNSQTTTMTGTLNNIGTGNPVAYTGMVRSPFRPSDDTAVFEFLVPSNMMFARYLETAAKITKQLSSAPQDLATQMEAMARNIREAISKHAVIEGPGNVGPMYAFEVDGFGGRNLMDDANIPSLLSAPFLGYLDAEDAVYQNTRKFALSKQNPWYCEGHVINGVGGPHIKPGAAWPMSSTVQIMTSSNNTEIEKALLELLSSTNGIGLIHESIKSDSAQAYTRPWFSWANGLFGQTILDLSKRKPELISKSYQSVIPEWAVSPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSB3</accession>
    <name>A0ABR3YSB3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Replication factor C subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rfc1</name>
        <name evidence="11" type="ORF">Cpir12675_005040</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the activator 1 large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000158">
        <property type="protein sequence ID" value="KAL1891250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17752">
        <property type="entry name" value="BRCT_RFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013725">
        <property type="entry name" value="DNA_replication_fac_RFC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012178">
        <property type="entry name" value="RFC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389">
        <property type="entry name" value="CHROMOSOME TRANSMISSION FIDELITY FACTOR 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389:SF6">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25361">
        <property type="entry name" value="AAA_lid_RFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08519">
        <property type="entry name" value="RFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036578">
        <property type="entry name" value="RFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="10">
        <location>
            <begin position="279"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="129"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="364"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="940"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="175"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="204"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="239"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="368"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="940"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="975"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="990"/>
            <end position="1000"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR036578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1891250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1000" mass="110572" checksum="F1057E21BAF7090E" modified="2025-10-08" version="1">MPDIRSFFQRPGGTDTPKKTNNESDKRSEADAESATRRARGRKVVDDDTDDDVVEIKKTPAKASTRKTKKEPEVEISASEYFSSNATKPKVKKPLDSSMEIPVRLSPMKKENIPQVKAPAATKRITRALLKHTPTPDEDAFKDDSGDDIFRADYGRKGDEDEYMEIDNDGEDIKRKARAKPVASKSKKRKASVTESESEVEGPKKKKPASAKPRAAPKAKTHTGEAPEIQDILDTIPTVRPPTPPPKDPSAKFDWRKAKGGGNAAAPPPLAGTVELPDGEEECLAGLTFVFTGLLQTISRDGAQALVKKFGGKVTGQPSTKTSYVVLGEEAGPSKLAKIKAHGIKTINEEGLFELIRKLPAYGGTGKGAEKAREKKDLERKKAEQEAKAMEAEEKRRKAEAEAAAKKAAVARGTAAPAAPAKVPVDPSAQLWTTKYAPTQMIHICGNKGNVEKIQTWLHNWPKHKKCDFQKRGADGMGGARAIIISGPPGIGKTTSAHLAAHLEGYDVIESNASDTRSKRMVEDGLSDVMNNTSLLGYFAGDGKDVDNKRKKLVLIMDEVDGMSAGDRGGVGALAKFCKKTEVPLILICNDRRLPKMKPFDLVAFNIPFQRPTVDQIRSRIMSICFREGIKIPVHALDAIIEGSNRDIRQIINMMATAKLDQSTMDFDKVKQMSKSWEKHIILKPWDICSRILAGGLFLPSSNATLNDKIELYFNDHEFSYLMIQENYLRCRPMAVNSTGFNNAREARLKALELFDQAAESISDGDLVDRMIHGPQQQWSLMPTHAVFSTVRPASYVYGSLGQPSFTSWLGANSKTGKLSRFVREIHSHMRLKSSGDYNEIRQQYLPVLWNQTIKSLFVEGKDAVPRVIDLMDSYYLTRDDFDSMMELGVGPQDESLVKIETQTKTHFTRTYNNMKHPMPFMKAATTGLPTKKLAKEVPDLEEAIEEDDDDGQADPEPNAEEKEDMDFKNDKYIKKPKAKKAPAKKAPAKKATAAPKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSU3</accession>
    <name>A0ABR3YSU3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Heat shock factor binding protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004990</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HSBP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000155">
        <property type="protein sequence ID" value="KAL1891376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009643">
        <property type="entry name" value="HS1-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19424">
        <property type="entry name" value="HEAT SHOCK FACTOR BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19424:SF0">
        <property type="entry name" value="HEAT SHOCK FACTOR BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06825">
        <property type="entry name" value="HSBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="80" mass="8381" checksum="604EED40179AADEB" modified="2025-10-08" version="1">MDSGGSPTSKPSASRGDAPPDDPHADLNAAVEELLNSLSNKFAGVSSEIFAKMDEMSRRLDSLETALAAKEKTGNENKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT02</accession>
    <name>A0ABR3YT02_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cell division cycle-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CDC25</name>
        <name evidence="9" type="ORF">Cpir12675_004951</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000153">
        <property type="protein sequence ID" value="KAL1891474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00155">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06224">
        <property type="entry name" value="REM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11883">
        <property type="entry name" value="SH3_Sdc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056685">
        <property type="entry name" value="DUF7783"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056686">
        <property type="entry name" value="DUF7784"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019804">
        <property type="entry name" value="Ras_G-nucl-exch_fac_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057827">
        <property type="entry name" value="WW_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF368">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25006">
        <property type="entry name" value="DUF7783"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25008">
        <property type="entry name" value="DUF7784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23518">
        <property type="entry name" value="WW_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00229">
        <property type="entry name" value="RasGEFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00720">
        <property type="entry name" value="RASGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 3" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="6">
        <location>
            <begin position="10"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="8">
        <location>
            <begin position="706"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="7">
        <location>
            <begin position="875"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="186"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="603"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="672"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="194"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="223"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="679"/>
            <end position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1127" mass="126696" checksum="E96CB7169A14B2E1" modified="2025-10-08" version="1">MNNLVGAAPPGTMFVRALYNYEADDRTSLSFHEGDIIQVITQLESGWWDGVMNGVRGWFPSNYCQIIESPDEIPDTTPDVVEDDEDDNPAYEDQFDQIEEEHSDEAGMPFEDAPSGDKSRADFWIPQATADGRLFYYNMMTGDRSSELPLESPVSTNETGLMDRPNVAIPDRTRLPLEMMARGLMRDEDEESLASISETDGENLGSSRGPMQQQIYSRTDTVSGPPSSSTAQAQPPLISSATSFTTTAFNLPTTANMSKSFFDDGTTPPLTWTRLVQNMKKAIARYREAVTSNDRAQYVARAEDISDHLRLLLAAGSGTTDNHSGQPSIISQNKALYPHFRDMMSKFSKLVISSHIAAADWPNAESVQKCLFEADGVFQGVFNYVEVARQQRGEEIPRLFPGFVIGSFTGGSWQNNGIGPRDRIAANFYDDDEGPSEPSAHLDDAILERIDDMKRLLISSLRELDKTLVLNDKIVTPARHELTGNNICAAGGKVLDAFKAWISLIENIDLSSMNHSVQQPILADFFTSKQSIYDNVADVIIGCQAVSGPLADEWSEVRGEALESRLEYVRQCATVLETNSAHLTFNLQGLVAYVQQYQSVQHGHGQRTESISGAREPLRRGDSNPYETGRIHQRQESRSTIPARPSMLSAQSFTEGEPVGNFRKGDMSKIKKIFGEDPSPQNSDSQTPPHLSLDLEHEISWETKITPHTVKGGTLEALVEQLTRHDKLDSSFNNTFLLTYRSFTTARELFEMLVKRFSIQPPEGLHTSNYEEWRVKKQMIVRVRVVNILKNWFDNFWMEDYNDDSKQLMRDVYNFARDTVKSAEAPGSAPLMAVLDQRLTGKEAGARRMVQKPDRSLPAAIMPKNMKKLKFLDIDVTEFARQLTIIESRLYGKIKATECLNKTWQKKVGEGEPEPAPNVKALILHSNQMTNWVAEMILAQMDLRKRVVVIKHFVSVADKCRSMNNFSTLTSIISALGTAPISRLKRTWDQVPQRSSNMLETMRTLMASTKNFGEYREALHAANPPCIPFFGVYLTDLTFIEDGIPSIIKKQNLINFAKRAKTAEVIRDIQQYQNVGYNLLAVPELQDYILSNMQAAGDVHEMYDKSLQVEPREREDEKIVRYVLPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTU0</accession>
    <name>A0ABR3YTU0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein arginine methyltransferase NDUFAF7</fullName>
            <ecNumber evidence="7">2.1.1.320</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_004844</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:48108"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:88221"/>
            <dbReference type="EC" id="2.1.1.320"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NDUFAF7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.320" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000147">
        <property type="protein sequence ID" value="KAL1891771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003788">
        <property type="entry name" value="NDUFAF7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038375">
        <property type="entry name" value="NDUFAF7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049:SF5">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02636">
        <property type="entry name" value="Methyltransf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="522" mass="60416" checksum="9B6DE2E143FD69ED" modified="2025-10-08" version="1">MDSPFIARLLRELFRRPACQLATGRSIKPLAAGPMSCPDRALTSSARISTTNFSLHHNQQRGYAIHRPGGNDRARDGMSNSESRWQQRTDIFPFDRAEEFDTYAMVTAEDLRSRKTRPRKVKMLMRDFIHDSLYNPSYGYFSKEAVIFTPGKPFAFHKMRDNLEFYSELSSRYVEFEDALDAAAGSPNPTRQLWHTPTELFRPHYGEAIARYLVSNYRLSSYPYHDLTIYEMGAGNGTLMRNILDYIHAADPDVYKRTQYRIIEISPQLAGLQASALADSPHAAHVEIVNRSIFEWNESVSSPCFFLAMEVWDNFAHDAVRYDDETEQPMQAIVLIDGDGDFCEFYSPMLDPLVSKFFRIRQSATGGVYPRPYSRSKLVRHLQSYIPLRPNLSDPEYVPTQLMEFFEILEKYFPRHRLVSSDFHSLPDAVKGLNAPVVQTRFERMMVPVTTPLVHQGYFDILFPTDFQVMESMYRAMTGKFTRVSTHEDFMRRWAYVEDTETRSGENPMLDYYQNASFIVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUJ5</accession>
    <name>A0ABR3YUJ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Monothiol glutaredoxin grx5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">GRX5</name>
        <name evidence="7" type="ORF">Cpir12675_004924</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000152">
        <property type="protein sequence ID" value="KAL1891552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03028">
        <property type="entry name" value="GRX_PICOT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033658">
        <property type="entry name" value="GRX_PICOT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00365">
        <property type="entry name" value="Grx4 family monothiol glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="GLUTAREDOXIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293:SF16">
        <property type="entry name" value="GLUTAREDOXIN-RELATED PROTEIN 5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="6">
        <location>
            <begin position="59"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1891552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="161" mass="17726" checksum="B97422D3DA9D7849" modified="2025-10-08" version="1">MSLRMVPRLVPSFLRAVCAPRTAPRFGAVLAPLGLQQQLRRLSDDTRHAIDKAVASAPVVLFMKGTPELPQCGFSRATIQVLGMQGVNPEKFAAFNVLEDPELRNGIKEYSDWPTIPQLYINKEFVGGCDIVMSMHQSGDLAKMLEDNGLLVEADEAENTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVL8</accession>
    <name>A0ABR3YVL8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004595</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000133">
        <property type="protein sequence ID" value="KAL1892308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF33">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046499998" description="AB hydrolase-1 domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="66"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="289" mass="31632" checksum="014EB1FB75F1E94C" modified="2025-10-08" version="1">MLGSSLLAALASVSAVSGLAVRQDTPKWLGLPETPALPLPVSDTLYDVNGIKMWVQKYNEKAGVTPLVMDHGGLGYSAYFGSVIQKLVDAGHYIIALDRRGHGRSTFNADDVFTYVQMADDIYKVLAQLNVNKYNVVGWSDGGITTLQALIDPVTAAPIEKAFVFGASISPDQTNPDFSNTEIYDQFVKRCLEEYGVLHPDVDFYLFGGKVQKMEAELPNFTKEQLASIDGSKLLIVGADHEEAVKQGVPDVIKEAIPRSTVKELTGVSHFAPLQDPQQFTDAIVEWFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVM4</accession>
    <name>A0ABR3YVM4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_004547</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000131">
        <property type="protein sequence ID" value="KAL1892433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1892433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="118" mass="13452" checksum="BF8C297C5C8E060A" modified="2025-10-08" version="1">MGYNYNRCCQCNTILAISDTCSLCHHEGCTECLSTPLPGSTLNYFDYASLTPRHIPSPPTVGAPLSREILSHRLSVKKSAERRERELREKAFREKERRDREVAMRRAENAAKAVLQEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW09</accession>
    <name>A0ABR3YW09_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_004526</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000130">
        <property type="protein sequence ID" value="KAL1892443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF20">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G10380)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="236"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="262"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="130"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="174"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="208"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1892443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="352" mass="38039" checksum="52E1A76A70E6269B" modified="2025-10-08" version="1">MRGLTSDPMANSEMSNGLAMPFDFETVGSMAPGSASQRYPCVQNPQSPNYEKDLSRWDQGYSEDSCASNWPSGNSMWGVSLEPQLDVGLNYDMSSCLDMTSPTLSTMSFGTNSGMPSALFSPLSLLSETPSDLSGQMSLLPTPSTTPVSVSSVSSSGQIFPAPASTPIRIEPVAAPPPPPPPPPPPLPSTSVASTQCRSSIPGFGVPLSMSLSESTRSSTAEPVRKTPTVKRVGTNQCETCGKLFQRTSELSKHRRYHLKDHKCTHNGCEAAFSTRKDLKRHINSAHSTSKTGHVCRMPGCGKNVSRKVYNRSDNFLRHLRTAHFHEDIDVTNALRTWLDDGPGSNDNNETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWQ4</accession>
    <name>A0ABR3YWQ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004598</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000134">
        <property type="protein sequence ID" value="KAL1892275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38848">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38848:SF3">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="466"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="481" mass="51816" checksum="86B301F2203907C9" modified="2025-10-08" version="1">MNSAANPPIHIRDGTALSHSTEPLGGTVMNVLLALVSTTVITAFLVQRSMNIKHWKRLPYVVWLVFAIYIDSYCFVFATAVLQLAFGVNSATTHSWFSQYIIRGSTKPRLKSKLYCFNCFFMLAIYVVVAILNFVFRITYIEDGVCVIGMRDVAMIPLISFDAVVNVYLTVMFLFPLKRLYSYSCSQRTPAQLRLRSVATRTFIGAVCTLVSSITNLTVLMALSGEPGWICLICCNSDILFSVLVIQWVTSKDNAGTSDSVNRPNCSADHTNGDSEDHALSYIDKSDNLRSRSTRQSTGHGSDGPGFTNASGSGSRGPTGSHSGPYSGHSCPNSHTATARAATIDNVSLSSDDSDIKYSSPRLHRHPLHAQTPGAVVVTTTIQRESKPTEAFLDGADNERLLASVVQKGRNGRFERPGSLTAVSSGGAGGSSAVIATATATTEQSDRPAEGDSGFQKSYLRHSSRTKAVTGQAKNNIGVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX29</accession>
    <name>A0ABR3YX29_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">dolichyl-phosphate beta-glucosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.117</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ALG5</name>
        <name evidence="15" type="ORF">Cpir12675_004313</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a di-trans,poly-cis-dolichyl phosphate + UDP-alpha-D-glucose = a di-trans,poly-cis-dolichyl beta-D-glucosyl phosphate + UDP</text>
            <dbReference type="Rhea" id="RHEA:15401"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19502"/>
            <dbReference type="ChEBI" id="CHEBI:57525"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.117"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:15402"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.117" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000119">
        <property type="protein sequence ID" value="KAL1892945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004581">
        <property type="term" value="F:dolichyl-phosphate beta-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04188">
        <property type="entry name" value="DPG_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035518">
        <property type="entry name" value="DPG_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10859:SF91">
        <property type="entry name" value="DOLICHYL-PHOSPHATE BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10859">
        <property type="entry name" value="GLYCOSYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="14">
        <location>
            <begin position="129"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00045097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1892945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="414" mass="45373" checksum="AB61861302C93D63" modified="2025-10-08" version="1">MPASMPIQRSLLAVLISIISSLLAARLSGLSLAILICVSLATIGLTCAPLALRLLHPKPRLPYPSEKKFIYAPANSHKTLGNYSSPSTLPCWFDAWLADDRHLQSQNFHIGEFYVPESEPLEAAELQLSVVFPAYNEEERILPTLTEAVAYLDRVYGRHKVASSAPPNSTPMGYEIIIVDDGSKDTTVTTALKFAAENNLGDSLRIVRLAKNRGKGGAVIHGFRHVRGAHVLFADADGATKFSDLEKLVQAIEKVVDGANRGIAIGSRARLVKNPEILKRSALRNFLMRCFHFVLTILTPAATSRIKDTQCGFKLFTRAALPHIVPYMRTEGWIFDIEMLMLAESSPPAPITAPGGSVIGTTQGIRVAEVPVNWHEVSGSKVNVVKDSIKMGWGLAVLRLSWTLGVYSRRELRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY03</accession>
    <name>A0ABR3YY03_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Enoyl-CoA hydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004380</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000122">
        <property type="protein sequence ID" value="KAL1892797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF171">
        <property type="entry name" value="SD19268P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="327" mass="35337" checksum="0ED6DCC81E074FA1" modified="2025-10-08" version="1">MIFPLSRAVRLQPRGLVLRFARQYSSASSTKSKSLIQVIDLPAPNSGHIRILELNRPEARNAISVQLLADLRQQIDAVSAQYGSAGEELPQKPLMGGSMGENKKGATRALILASAVESCFCAGADLKERRSFSSEETDRFLSFLRSTLSSISSLPIPTISAISSLALGGGLELALSTTFRVLSSTAEVGLPETRLGIIPGAGGTYRLPALIGLNRARDMILTGRRVSASEAYFLGLADRLVEVAPEGEEEKKQILDLARRAVLSESVRLAQEICDGGPIAVRAALEAVQWANPDVENKMYQRVVSTEDRDEALRAFSQKRKPVFSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYH5</accession>
    <name>A0ABR3YYH5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61</fullName>
            <ecNumber evidence="2">2.1.1.220</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">tRNA(m1A58)-methyltransferase subunit TRM61</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">TRM61</name>
        <name evidence="12" type="ORF">Cpir12675_004092</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.220" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000109">
        <property type="protein sequence ID" value="KAL1893439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030731">
        <property type="term" value="F:guanidinoacetate N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049470">
        <property type="entry name" value="TRM61_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014816">
        <property type="entry name" value="tRNA_MeTrfase_Gcd14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12133">
        <property type="entry name" value="TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12133:SF2">
        <property type="entry name" value="TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE CATALYTIC SUBUNIT TRMT61A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08704">
        <property type="entry name" value="GCD14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51620">
        <property type="entry name" value="SAM_TRM61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 12" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61 C-terminal" evidence="11">
        <location>
            <begin position="135"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61 C-terminal" evidence="11">
        <location>
            <begin position="306"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="79"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="458"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="458"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="478"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="493"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1893439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="506" mass="56489" checksum="47ECB3A647DC4A1F" modified="2025-10-08" version="1">MTPTNHQPSPFLSSSTRSKTNSLSLVYLSRENLVPLILQDSRQTGVFDGYAEGATLNSRFGSFPHSTLINVPWGSQVRASNVDTGSRGRKRKRNRAEQEEDEASEVPTAASAAGDSQTDAPSSAVVKKAVTAASGFLHILKPSPELWTLSLPHRTQVVYTPDYSYVLQRIRAFPGKRIIEAGAGSGSFTHASSRAVYNGYPTSPCDPRGKVFSFEFHEVRYQKMTEEIKSHRLSGIVQMTHRDVYNGGFLVNENQSPQANCIFLDLPAPWEALHHLSRRQQGKAGEVLKDEDRDPNWVSPLDPNDTVYLCTFSPCIEQVTRTISAMRRLGWVDIDMVEIAHKRFNVSRDHMDKTMATPIVDVEDAVAKLDASLNKPQKGAHFRRLADKTAKQNGRPVQAENTKPWLEGRVIHRPEAEIKSHTSYLTFATLPREWTAEDEARVLALLPPCSSSKVIGSLDKEARRKEKEEAWKSKAKKNIQTGRMTVPVTDNTKNSESKEPKQESNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZC1</accession>
    <name>A0ABR3YZC1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Xenotropic and polytropic retrovirus receptor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SYG1_2</name>
        <name evidence="8" type="ORF">Cpir12675_004302</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000118">
        <property type="protein sequence ID" value="KAL1893068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004342">
        <property type="entry name" value="EXS_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783:SF103">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 53 MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783">
        <property type="entry name" value="XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03124">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51380">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="EXS" evidence="7">
        <location>
            <begin position="11"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="296"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="264"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="317"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="349"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="364" mass="40584" checksum="A1EC0A81708F52FB" modified="2025-10-08" version="1">MTSKSWKQPEVCNSSHSPIMGFLAALPPIWRSLQCLRRYYDTRNWFPHLINCGKYAMSIMAAISLSMYRIDRTHTNFALFVSFGCINGIYTAIWDLFMDFSVLQPGARKYLLRDILGLKKQWVYYVIMTLDPILRFSWIFYAILRNQTQHSAAIAFGVAMSEVIRRGMWSLLRVENEHCSNVAQYKASRDIPLPYKIELCDEMTAAAINAGKKAHQFGSPDLATASTDSAASPLSGTTISHNGVYTSGAQTSAPIAADVEQHAGGSSSMQHRRNGTTGTVGTIGMAISRIMAEAHRQDFEKRRKPEDDEPEMRGGGDEDDEFYYDDDDDDEMDQSDGPSTQCGLPASANVRSSMGFESNSRAKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0P7</accession>
    <name>A0ABR3Z0P7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003936</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000101">
        <property type="protein sequence ID" value="KAL1893867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="346" mass="38617" checksum="128288169D3677D4" modified="2025-10-08" version="1">MEDINMADRESQPREAEKPKENPTPDLPPPPLTHDTITQTHDTNKTVGNTESLPGQTTPKEPTPQKKNTKPTENTKKAPVTGAFVDILNKTWEEEKKRMEDTARGIRVLTSQMDGLTAAENLDGVGKAGQQAYKDILRRVMAVIEEEIRQKLTGTRGNTPATNTAPKPTTAQKRAPQTWAEKAAAGKTTQALKLKGTTPKAQANASPALPETPKIPRRKIDENRLLAILFEDSNWKMVNPTVVRQRIKRYPFKGEEVILRMASTRTGFAFHAKEGKMDTEAKELNRNFLKARTMGKESFWEKFIIPNVSKAINTIEDGKLVTRPTNMEDVKPDIQVAFGGEIKIMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z133</accession>
    <name>A0ABR3Z133_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">40S ribosomal protein S28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPS28A</name>
        <name evidence="4" type="ORF">Cpir12675_003705</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000092">
        <property type="protein sequence ID" value="KAL1894323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04457">
        <property type="entry name" value="S1_S28E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00292">
        <property type="entry name" value="Ribosomal_eS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000289">
        <property type="entry name" value="Ribosomal_eS28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028626">
        <property type="entry name" value="Ribosomal_eS28_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10769">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10769:SF3">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN ES28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01200">
        <property type="entry name" value="Ribosomal_S28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00961">
        <property type="entry name" value="RIBOSOMAL_S28E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="68" mass="7782" checksum="0D3FB6AC144EB80F" modified="2025-10-08" version="1">MESAKVQVKLVKVTRVLGRTGSRGGVTQVRVEFMDDQTRSIIRNVKGPVREDDILCLLESEREARRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1E4</accession>
    <name>A0ABR3Z1E4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transaldolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003798</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000096">
        <property type="protein sequence ID" value="KAL1894110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42105">
        <property type="entry name" value="DIM2-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42105:SF1">
        <property type="entry name" value="TRANSALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="686"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1016"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1243"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1322"/>
            <end position="1364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1403"/>
            <end position="1427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1453"/>
            <end position="1582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1641"/>
            <end position="1753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="441"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="453"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="714"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="725"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1032"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1063"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1252"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1322"/>
            <end position="1331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1353"/>
            <end position="1364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1493"/>
            <end position="1502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1556"/>
            <end position="1580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1641"/>
            <end position="1654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1723"/>
            <end position="1733"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1753" mass="192015" checksum="137B58E27920D11E" modified="2025-10-08" version="1">MGLDSSSLFLPAPTETESVIAPSELGTELSRNDEHSVYSLPSDGTPVTISNRKTRAKITQPGASVLIEYFENGSTVSDTTDRKPSLRVRLTPSRPSHIEQTAISHTKSRSSRRRSELGEIEDALMSPYASATEESTVSRNHVDTETERIVMPKQRSGKRPVSPLIPEARMSNPPSSGPPPNAGTGSDLSVIPTNSFLDDSGNSVYGENKRSASPLAKTRGQKPRQGERERIRLADKPIEKEREKRSKSKSGRSRTSSLSAVQKERERERERFRDSELNYEGYSHISHRDSIGHSSKSRTRRSSRGQGQESFVSGVESGLSSTVSRAPDGQSTRSSDVNSKLLAAVEVALRRVVIPELEAIKRENSKRESRRVSGGSSATTVSRDDVSESTHHRRRSSQSRHRASDRGHERELDRERTRERTRERERAVISPESVDDYYADTPKRSPDNYHTRSSLSSAVAASTVMASAVSGRGKSPPPPEEKKSRRRRRDAPRKRPSDRYDNEFDDESVAPQPPMPLMSEINPSELTRLSLRTVDSDRPASAMEEVTKSEVSDGGALLQPGLKDLQLGMQYANISHGDLRALPRGNKEQGLEYRQNNGPAPFPEEYEPNEYGQKVPTRMRQEPVAEMYDQAEHQAQNEGEYERDDYDHFYGQQDVPAHLKYVPYQPERRGLSPIYSVSGYTETSELAARESHVASNSEEYQSPPMSPRHHRHSSLISSNLLNSDGLPQSEISSTTGYPRNSAYTDDMSELDAEPDQPVRGIGTNPKIIPGAPIESVVASLVDGSVMEQSVMTSNTHAYGYLGPESNVSYGVARSAVSYGPESVMSEDPRHTIRELTIKKKQSDVVMSDAPLAEEQYDDPIDPDDFDRSVTPTAVEQAAFAAITSGALAKVVQAKQIQIHATSKDDVIAGGGAGVARNKSFKQRTMEGHEIATTPAHSVDRFGDEQGLKLSASALPDFDNPMPEYGDHMDFDSDITASLEQHLDVKSGNRERGQELSFVAGAADSISIAPTRDMSELDYMDDGNMTPRALSPKKSTLNTDSNVATADSTVGVRTQSSAGDREEEATRTSAERKRETILTNPYENISPLASNRLSEAFGFSEEVHLPKDEGYVSNGPNRTPDNFNMEDIKGVSMPSAPGFGGVDDSFLTRRMSGLTPGPETPLYDPGMTSSGSIQNRDIMTLMQDLVARDAQRNARDTEIAAMVMFLANEMRTQFKTVEERIKQAEDVIIDEVQDSEKMVIKAINGPRPYPGPSSVSRSLAGTATANSSNPGPEIALATKRGNILRRALNGLNVTGAKDLSRIEVMLHQLLDEVMELKDHQVQNHPRASSTLENFGGENDTVDGGYDPEGHAGTSIASHGSQQLSATRINTSRSGHFDRKYSDHRVSTVHEGDEEEAQTVVYNNSNSEHDHDRMGTPSRNQETGPRGESIVMATPSREPAIPPAAFAQTSAAALPGASPMATEPEGSPKSAGKSEKSRKHKSVGSSGLGARISRWSETTASTLSKAFRSSGGSSKKNEPYMQNVDGRSRSGPDFAGHNDSSYRPRTAPYSNDGLHTGFSDQNLDRTPSPIASGTPTMPSYVNQDHPKYHVHRNSLNLQHPQPRQGNSERFKNNLETQAHIYDTVNTPRSADWGHSMTSLSRFNAASTPQQNPQGESSMAPPRPPKEALETTGTPRSARDTQHGYASGGTAHHTGLPADNRSRDVDRLAGMPTRRPSGPRAMTPKSQHDESYEERRRNRNTFGSVASRASADTDTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1J2</accession>
    <name>A0ABR3Z1J2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TAFII28-like protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_003855</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000098">
        <property type="protein sequence ID" value="KAL1894071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08048">
        <property type="entry name" value="HFD_TAF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045127">
        <property type="entry name" value="TAF11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006809">
        <property type="entry name" value="TAFII28_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13218:SF8">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13218">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04719">
        <property type="entry name" value="TAFII28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TAFII28-like protein" evidence="7">
        <location>
            <begin position="173"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="260"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="91"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1894071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="326" mass="35958" checksum="D8B2C0435959BB26" modified="2025-10-08" version="1">MASPPFPQSSSATSPTYSSYQNPSTISKKRSATDMTSAPHKRRKASMISLSHPLRQTSFPPESLLENGRRSPSVDAMSFVSGSQVSTTEKPKKKRGRKSKKELAENSSFGESSSTVAGPTSTVGGGSNAPGKESGKKQQEEEEEQLGPLQMELVDSSAGTKEKKQEENRLRGMLVEAFDPEQYNRYERWRAAKLGESTVRKVVNAAASQSAPPMGILAMKTVTKLFIGDIIESARRIQTEWIHAGVEPLLEIPVISPEDFTADGEKKEPEKVKRRGPLRPEHLREAARRYRVSKEGGTVGMQSPWHTQQQTGVERFSVITGKRIFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1X9</accession>
    <name>A0ABR3Z1X9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 15">CDP-diacylglycerol--serine O-phosphatidyltransferase</fullName>
            <ecNumber evidence="4 15">2.7.8.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14 15">Phosphatidylserine synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="primary">CHO1</name>
        <name evidence="19" type="ORF">Cpir12675_003768</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>a CDP-1,2-diacyl-sn-glycerol + L-serine = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16913"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="2.7.8.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="15">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15 16">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.8" evidence="4 15"/>
    <dbReference type="EMBL" id="JAWDJO010000094">
        <property type="protein sequence ID" value="KAL1894287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003882">
        <property type="term" value="F:CDP-diacylglycerol-serine O-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050324">
        <property type="entry name" value="CDP-alcohol_PTase-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004533">
        <property type="entry name" value="CDP-diaglyc--ser_O-PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016271">
        <property type="entry name" value="CDP-diaglyc--ser_O-PTrfase_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00473">
        <property type="entry name" value="pssA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269:SF61">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000852">
        <property type="entry name" value="Phosphatidylserine_synth_fun"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 15" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10 15" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11 15 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="12 15" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="13 15" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 15 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR000852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1894287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="245" mass="26806" checksum="BD3F5938F5263D96" modified="2025-10-08" version="1">MSKRLSVSSGNGNSAPFATASKPLLPHNDKQRLLLSADTGHFSLIRAMHLADLITMMNGFCGVMSIFTSLRYCLGNPADLDIMYVALAFLPFGLFFDFLDGRVARWRKKSSLMGQELDSLADLISFGVAPASAALALGFRSTLDTVALAFFVLCGLARLARFNVTVALLPKDASGKSRYFEGTPIPTTLGLDAIMAYWVSKNWVLSELPWGMWFEGTPLEVHPVVIMFVIHGCLMTSRSIHIPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z231</accession>
    <name>A0ABR3Z231_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">H/ACA ribonucleoprotein complex subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Nucleolar protein family A member 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SNU13</name>
        <name evidence="8" type="ORF">Cpir12675_003808</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Common component of the spliceosome and rRNA processing machinery.</text>
    </comment>
    <comment type="function">
        <text evidence="6">Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
            <location evidence="1 6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the eukaryotic ribosomal protein eL8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000096">
        <property type="protein sequence ID" value="KAL1894120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002415">
        <property type="entry name" value="H/ACA_rnp_Nhp2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004037">
        <property type="entry name" value="Ribosomal_eL8-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018492">
        <property type="entry name" value="Ribosomal_eL8/Nhp2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00881">
        <property type="entry name" value="L7ARS6FAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00883">
        <property type="entry name" value="NUCLEARHMG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01082">
        <property type="entry name" value="RIBOSOMAL_L7AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="7">
        <location>
            <begin position="18"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1894120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="125" mass="13721" checksum="EBE3CEAB7A02CCF4" modified="2025-10-08" version="1">MDDQQAVWPRADEALEQEIYSLVQACHHARQLKKGANEATKTLNRSVSELIILAADTAPLAILLHLPLLCEDKNVPYIYVGSKTALGRACGVSRAVISVSITSNEGSELADRIRIIKEKVERQAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z234</accession>
    <name>A0ABR3Z234_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cation/H+ exchanger transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_003591</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000088">
        <property type="protein sequence ID" value="KAL1894603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43562">
        <property type="entry name" value="NAPA-TYPE SODIUM/HYDROGEN ANTIPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43562:SF2">
        <property type="entry name" value="SODIUM-HYDROGEN ANTIPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0050">Antiport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="275"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="380"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="454"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="10">
        <location>
            <begin position="44"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="514"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="591"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="524"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="632"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1894603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="643" mass="70719" checksum="EF1FD2E6DC0D6F0A" modified="2025-10-08" version="1">MAFSMDISETYVRQSVVAPEGTFIEYLEPNLVEILIFISFFFLLSISEWISSKVFKVGPIGQMIVGMLYGVPIGNILTIPMQQVFVGLGYIGLVLIMFEGGLTLNLDSMKGHYRIVIFSGTIALMVPMAVSFGFLYAGLDYGAVETFIVGAALSATSLSHTFLVIHTVVKDYDFSRTRIGTILIGAVVLNDMVGLVTSCVIEQVGEATGGHHHGIPHRPETEHEKKSLATAIWRPIVAAIGISIVIPLLTKYLFGPVFRWYIEPYFVRFKHVSNITLMVFTLAAFMTLASYCGTSMLFGAFVGGLVLSRLPCIHPDAPFMVVSRQDGETQYGKTPNFAHTFEKYIIGGQTYILQPMFFASVGFAIPVKDLWSGTVLWKGAIYAVLMLLSKVSISLVIPLYDIINRRPLPATSYFLRRIWQPSLIMGFGMVARGEIGLLTIMIGHNHTDFLSREAFIVGIWAIILNTMIGPFFVGLIMRRFGSSLARDPRWGLMDDDEDANVRAWDAMSTGQMSARGRWTNRMNSRSVSRAGSRTGSRSGSRNGSRPTTQDKDMRRRSSTRASDSGDAAERGCAGHVVAVVPVSLAVPFPSLLSPGLSPGVSARPSMEQSRRGSDQAGSSSDQPRRSAEQPRPNLQQQSRRMSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2C0</accession>
    <name>A0ABR3Z2C0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PRE3</name>
        <name evidence="9" type="ORF">Cpir12675_004006</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the proteasome complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the peptidase T1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000105">
        <property type="protein sequence ID" value="KAL1893659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03762">
        <property type="entry name" value="proteasome_beta_type_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000243">
        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF0">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE SUBUNIT HSLV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6 8 9" id="KW-0647">Proteasome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0888">Threonine protease</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="229" mass="24994" checksum="5410800724DC2254" modified="2025-10-08" version="1">MEFGNSGVINEDGIHVDMDRLKKGEVNLGTSIMAITFKDGVILGADSRTTTGAYIANRVTDKLTRVHDTIWCCRSGSAADTQAVADIVQYHLGLYSAMHGKPPTTQTAAALFQEICYDNKDRLSAGLIIAGWDEQHGGQVYSIPLGGSLHKQSYAIGGSGSTYIYGYTDAHWKEGMEEAEAVDFVKSSLREAIKWDGSSGGVIRMVVLTRKGADRHLYLPDTDYKVRHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2G5</accession>
    <name>A0ABR3Z2G5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein arginine N-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_003464</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000083">
        <property type="protein sequence ID" value="KAL1894819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007857">
        <property type="entry name" value="Arg_MeTrfase_PRMT5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035075">
        <property type="entry name" value="PRMT5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035248">
        <property type="entry name" value="PRMT5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035247">
        <property type="entry name" value="PRMT5_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10738">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10738:SF0">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05185">
        <property type="entry name" value="PRMT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17286">
        <property type="entry name" value="PRMT5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17285">
        <property type="entry name" value="PRMT5_TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015894">
        <property type="entry name" value="Skb1_MeTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="Xylose isomerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51678">
        <property type="entry name" value="SAM_MT_PRMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PRMT5 TIM barrel" evidence="7">
        <location>
            <begin position="40"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="PRMT5 arginine-N-methyltransferase" evidence="6">
        <location>
            <begin position="371"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="PRMT5 oligomerisation" evidence="8">
        <location>
            <begin position="553"/>
            <end position="761"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR015894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="775" mass="86419" checksum="3B5EA82C1F39CCDE" modified="2025-10-08" version="1">MAYNQAQEPTWPRILLGYHDSSLEQPLNDLEYGKAVSQGISYLTSPITNSHFRQRITELVKNHLQSLKGINSSATADLTAAIPDPIIPPLTIKDTSLFPSFSVSTYNACTSSWIDLASSDPVIANISRQVLNLELAYATWCGVRSVVIHGPRQDSARGNANKGLAQYARAIREALTVASRQNITIHMPMYREPGLDDSNPPLTETVHGSEAESQKPSEIALFSAWDSWHFVRTFCEYNPRLFVGVRMPKVMAGKELQTRWFAEPLNFISMSPEIFQANKAGFPSLPKHHQELIFSYMRLKTTPWVLLCDIDLDLSAGDPGDALSKNEFPTLADSVQKADQRKPAAGSSYISYIQWLESQQNPYSNLENSTLISFQDWLQSPLQPLSDNLESATYEVFEGDPVKYNQYEAALVEALTEWKTLNKPTSSKSGAVVVAVAGSGRGPLVTRALNASKTTGVPIEAWAVEKNPNAYVYLLRQNEFVWERQVTVVKTDMRAWKGPLLSESTYEKPVYGKVDILVSELLGSFGDNELSPECLDGIQHVLAQPHGISIPHSYTAYLTPLSAPKLHQDIIHNKVPIDPHAFSTPYVVQLYSHDFVCDRGVPGHTRFQQTWEFSHPISEKTLALIEARKSGGVIGGGGGSMAGAAGVNDHNYRQCHLTFVARNKGVVHGLGGYFESTLYQKQIGEPTKIEISILPEQIDNKSKDMTSWFPIYFPLTNPIDFPADSEIEVFMWRQTNDTKVWYEWQVEVYTWIGENQRIKIATSALCSSYTVACLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2H5</accession>
    <name>A0ABR3Z2H5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003644</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000090">
        <property type="protein sequence ID" value="KAL1894467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12460">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12460:SF38">
        <property type="entry name" value="KINETOPLAST-ASSOCIATED PROTEIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="211"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="240"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="120"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="422"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="516"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="42"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="141"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="425"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="517"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="640" mass="70769" checksum="B12DB9EF92EF3564" modified="2025-10-08" version="1">MTDTPADVLVEARRNLQALIDSGISKEALLALLYDSPANAAQQSQQRRPSSQMQRSQTTPIEEEIPKMISMAQSQQSQPQSQISRAQSQPDIRLAASPMQQQMQMLPQAQQQNIDGQAVPMPMFAPPPIPFDRRGHHPRFSISSTSSGSSGHASIWSQTSSLSTASSTGSTYGAPASGASGSTGSSACSSNSGGSSPAAAAAWSNNRQNFYWCTSCDTRFKRKYDWKRHEEEFHERWKKYPCPEPGCNRSFWGANTFNQHHKSSHGCRTCPHSEKVVKYLRKRKYWACGFCSALHPSRERHVEHVARHFESGKSKTDWMHSRVIYGLLHQPLIHEAWKELVMSKYGESAPSFSWNPTKTGRAQGFMENECPGQLQDLLEFFSGPISEAKSIVQIAYDLSDIVFAAAAAAAAAAAAATSLALESPSRASNMSYPTPPESSLSPISPGHSMIPQHSPQQQKMEPIQMQQQQQQLRQFQMQMQQQNRHGAQMMMGTEPTSPTSFPGYHHQSMMQPGMFAQVNSPHSTSAQNSLPPQIPMKTSSSSLRRTSMERDLPPPPPPETQAPMSYDFMPTVILDGWSSFSNTVVDEPMHAQAQAQAQVQAHAQAQAQAQAQAHSQMQAQAQHQTLQTDWPVMQFYAPSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3I6</accession>
    <name>A0ABR3Z3I6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Osmotic growth protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">OSM2</name>
        <name evidence="7" type="ORF">Cpir12675_003520</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000085">
        <property type="protein sequence ID" value="KAL1894779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050315">
        <property type="entry name" value="FAD-oxidoreductase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010960">
        <property type="entry name" value="Flavocytochrome_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01813">
        <property type="entry name" value="flavo_cyto_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400">
        <property type="entry name" value="FUMARATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400:SF1">
        <property type="entry name" value="FUMARATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="6">
        <location>
            <begin position="538"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="494"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="498"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1894779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="622" mass="67216" checksum="65295130DBF663AD" modified="2025-10-08" version="1">MAPRVIVVGGGLSGLSAAHTIYLNGGNVIVLDKQGFFGGNSTKATSGINGALTRTQVDLKIQDSVKQFYEDTLKSAREQARPDLIRVLTYNSASAVEWLQDIFGLDLTLVSRLGGHTHPRTHRGHDAKFPGMAITYALMQRLEELAETEPGRVEIIKKARVTGLNKEGNKITGVKYEHEGNSLSLDGPIVLATGGYAADFTDNSLLKKYRPDTWDLSTTNGSHATGDGQKMIMEVGGNGIDMDKVQVHPTGLIDPKDPTAKTKFLAAEALRGEGGLLLNADGDRFCDELGHRDYVSGMMWKEKAKNKFPIRLVLNSKASNVLDFHTRHYSGRGLMRKMTGKELAKEIGCSPEHLQKTFKTYNTYASGKEKDPWNKKFFHNVPLDIDDDFHVALMEPVLHFTMGGVEINDKSQVLNQEKKPFEGLYACGELAGGVHGANRLGGSSLLGCVVYGRVAGDSASNYLFQNALQGAAGASSRLGQISLHIDPSLPGRVQVEWGSGSSSAGPSAALSAPAASSNSSTSSAAPAKEAAKPFSIPDKEYTMEEVAKHNTKGDLWVVVKGVVMDLSDWLEEHPGGPQAIMNFMGRDATEEFEMLHDDEVIPKYAPHQVIGRVAGVTPTLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4G3</accession>
    <name>A0ABR3Z4G3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Rhomboid family membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003213</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000072">
        <property type="protein sequence ID" value="KAL1895524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="191" mass="21688" checksum="1055972C9DF81173" modified="2025-10-08" version="1">MANPNPTTNKTIFGEIQTDTPVWLHTSVIVLAAASGLAILLPPRRFDLRLLVLSSTFSLSTSQLAYDYTGKSIMERFGSRMEAMGALSTPELSDRSKEVRRLLREEKMRHMTDAQRAEEARKQREKDRSILQKLWLGDEDEDWKEKRMVEDRKALEEGKGISGIIMDQISDVFHGNDSKDKSEKDGGDKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z516</accession>
    <name>A0ABR3Z516_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Karyopherin transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CRM1</name>
        <name evidence="9" type="ORF">Cpir12675_003258</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the exportin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000074">
        <property type="protein sequence ID" value="KAL1895352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041123">
        <property type="entry name" value="CRM1_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041235">
        <property type="entry name" value="Exp1_repeat_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045065">
        <property type="entry name" value="XPO1/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014877">
        <property type="entry name" value="XPO1_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040485">
        <property type="entry name" value="XPO1_repeat_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223">
        <property type="entry name" value="EXPORTIN 1/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223:SF2">
        <property type="entry name" value="EXPORTIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08767">
        <property type="entry name" value="CRM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18777">
        <property type="entry name" value="CRM1_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18784">
        <property type="entry name" value="CRM1_repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18787">
        <property type="entry name" value="CRM1_repeat_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01102">
        <property type="entry name" value="CRM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="8">
        <location>
            <begin position="26"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1895352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1079" mass="123582" checksum="7723D59870827029" modified="2025-10-08" version="1">MTLTVPELDALAQAFFEGRGSQQKQAQDALNQFKEDPDAWLLVDQILSEATYPQTKYIGLQVLDNVIMTRWKVLPREQCLGIRNFIVEFILKCSSSEEELKSSKTLINKLNLVLVSILKQEWPHNWPTFINEIIQACHKSLSVCENNMIILRLLSEEVFDYSADQMTSAKTRNLKTTMCAEFSQIFQLCQEILNTANSVSLVKATLETLLRFCNWIPLGYIFETPLIDTLRTRFLSVPEFRNITLQVLTEIGGLQTSGVGSPSNYDEQLVKMFTEVLTTIADLIPLNLDLRTTYPQSNSKDQEFIQNLALFLCNFFSMHLNLIEKLPNRDFLTHGHFYLIRISQIDDRELFKICLDYWLKLVQELYDEMQALPIADLNPMLALSGGVSSGGAPNPSLLADYPLRKHKYTEVMCNLRVVMIEKMVRPEEVLIVENDEGEIVREFVKESDTVQLYKTIRECLVYLTHLDVVDTENIMTEKLSKQVDGSEWSWHNCNVLCWAIGSISLAMNEETEKRFLVTVIKDLLGLTEMKRGKDNKAVVASNIMYIVGQYPRFLKAHWKFLKTVVNKLFEFMHESHEGVQDMACDTFIKIAKQCRRHFVALQPSEQEPFIQEIVRNMNNITCDLTPQQIHTFYEACGYMVAAQGNKNTQEHLLADLMALPNVAWDEIIKQANINPGILQDSETIKIIGNIMKTNVSACSSIGTYFYPQIGRIYSDMLQMYRATSSLISDAVAKEGEIATKMPKVRGLRTIKKEILKLIETYIEKAEDLNAVRQQMVPPLLEAVLTDYNTNVPGARDAEVLKSMSVIITKLGSLMEDQIPIIMQNVFECTLDMINKDFSEFPEHRVEFFNLLRAINLKCFPALLKLDNRQFKFVIDSCSWAFKHDNRDVEAAGLNMCLELINNIAETDVQTSNLFFQQFFISILQDVFFVVTDTDHKAGFKTQSMILMRMIYFVHPADGTSPKIQGPIYNPEQAPQGTGNQEFLSNFIANLLRSAFPNLQPAQIQSFVEGLFTFNTQYDRFRLSLRDFLISLKEFASDNAELFAFEKEQRDRESKAADYERRTKVGGLLKPSEIVDEEDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z532</accession>
    <name>A0ABR3Z532_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_003139</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000069">
        <property type="protein sequence ID" value="KAL1895748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050324">
        <property type="entry name" value="CDP-alcohol_PTase-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269:SF60">
        <property type="entry name" value="CARDIOLIPIN SYNTHASE (CMP-FORMING)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1895748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="314" mass="34521" checksum="25B26B841AAF6C7D" modified="2025-10-08" version="1">MNVLLRSVSSYRGISQSSTKVPHLSVLLSVQGHHHQNYNRDHSTLALSTGTNTLARNLVHNTPKLWATRSFSSRLTSWNKSQKTQAPEKNTIPVAPISNATVPASVSAKKPTVLEVHEDIYTLPNILTFSRLLASPAIGYLILHDHRAWAVGLFAYAGITDMLDGWIARKWNQRTVVGTVIDPAADKALMTILTVCLAMKGGLPVWLAVIILGRDVGLAISAIYYRYISLPAPKTFKRYWDLSIPSAEVHPTTISKVNTALQLGLIGLATAAPIIPYDLTTVLNYFQYIVATTTIWSGASYIYSKDAVKILKKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5F3</accession>
    <name>A0ABR3Z5F3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12">Mannosyl-oligosaccharide glucosidase</fullName>
            <ecNumber evidence="11 12">3.2.1.106</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Glucosidase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">CWH41</name>
        <name evidence="17" type="ORF">Cpir12675_003066</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>N(4)-(alpha-D-Glc-(1-&gt;2)-alpha-D-Glc-(1-&gt;3)-alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] + H2O = N(4)-(alpha-D-Glc-(1-&gt;3)-alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] + beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:55988"/>
            <dbReference type="Rhea" id="RHEA-COMP:12806"/>
            <dbReference type="Rhea" id="RHEA-COMP:14355"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:59082"/>
            <dbReference type="ChEBI" id="CHEBI:132537"/>
            <dbReference type="EC" id="3.2.1.106"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="13">Glycan metabolism; N-glycan degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Endoplasmic reticulum membrane</location>
            <topology evidence="1 12">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the glycosyl hydrolase 63 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.106" evidence="11 12"/>
    <dbReference type="EMBL" id="JAWDJO010000067">
        <property type="protein sequence ID" value="KAL1895788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004573">
        <property type="term" value="F:Glc3Man9GlcNAc2 oligosaccharide glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.110">
        <property type="entry name" value="Glycosyl hydrolase family 63, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031335">
        <property type="entry name" value="Glyco_hydro_63_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031631">
        <property type="entry name" value="Glyco_hydro_63N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038518">
        <property type="entry name" value="Glyco_hydro_63N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004888">
        <property type="entry name" value="Glycoside_hydrolase_63"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10412">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10412:SF11">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03200">
        <property type="entry name" value="Glyco_hydro_63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16923">
        <property type="entry name" value="Glyco_hydro_63N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 12 17" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 12 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045280817" description="Mannosyl-oligosaccharide glucosidase" evidence="14">
        <location>
            <begin position="19"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 63 N-terminal" evidence="16">
        <location>
            <begin position="40"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 63 C-terminal" evidence="15">
        <location>
            <begin position="306"/>
            <end position="802"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU368089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU369107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF03200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF16923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1895788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="817" mass="92905" checksum="35B52CDD68746B72" modified="2025-10-08" version="1">MAPWRSWAAGLLLASSAAISSEEGNRLSISQEIDALNNQSLFWGPYKPNLYFGARPRTSKSLWAGLQWVNANEYKQLSQGYRYTCEQHDSISGYGWEEYDVRNGGSQVIHDDANEIEITTTFIKVPGGKNGGSWAVRVKGVPYSTARPDLTTLLSFYIAQEEDNGVLEVGTLGTPQGFVDEVTLVGTSPSLGNYKLTITKGKGETPFSEHAITESRQPEKTVVRSLKVSEEVAWQGRNVAYNQINEALKYVTETFDVENDLPPPYLSYLLDNSPGAGNVHIVQKIFQGEFEFDFILNSEDADEVITSETIDKKALENSKSYDKRYSELFEPQAPFVGEDFVKFGKSMLSNLMGGIGYFHGDQVIDRSYAPEYKEEEEGFWQGTAEARERHAEKLEGPFELFTSVPSRPFFPRGFLWDEGFHLIPMADWDVDLTLDIVRSWFKTIDEDGWIAREQILGPEPRSKVPAEFQVQYPHYANPPTLFLIVETFMNRLRATGIKKNPSPITKDTPLRNAHLDYPQAGLEFMQEIYPLLRRQYEWFRRTQKGDLINFDREAANEVEGYRWRGRTETHCLASGLDDYPRAQTPHPGELHVDLMAWIGLMTKSLYSIADSLNLKEDAAVYASHLSNIQKNLNALHWSKKAGCFCDATIDEFEEHMLVCHKGYISLFPFLVGLMDPQDPKIDRLLDMMEDPAHLWSPYGLRSLSQSDEFYGTAENYWRSPIWININYMAITRLYDLASVAGPHQDRAAELYAKLREAVVMTIYNSWKETGFAWEQYDPDTGRGQRTQHFTGWTSLVVKIMAMGQPDAEGSRATHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6G0</accession>
    <name>A0ABR3Z6G0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003143</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">CMW 12675</strain>
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        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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            <begin position="1096"/>
            <end position="1117"/>
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            <end position="1192"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="998"/>
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            <begin position="1"/>
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    <sequence length="1194" mass="127776" checksum="A90F2DAB66777C70" modified="2025-10-08" version="1">MSSSHPPRTPSQAHSGSSRRETCSSVSSSQLTRGIRVVPYSPPRAADSSRSQRSSIASQYTSANLVVDDTSRSEADSDYNNDREDYHIENTDIGSDSDSAGENICHEDLQKNDEDDLFGYWPELSFDFSEETSSSEPSLQPISFIQQTSLLMVDETVMSEADSTQSSFGGLQATNSSQVSGLSGTQVSQAPGANTSVYKSSQWGVSAVPGKASSDSRDVTVHHDDPPASSSFFSSSSLSSAFDQSQSKSSLSFQARSRSSSSVSSDQEVRPSTAHKRRNLLTVSSNGKTFSLTPLTPVSGSGSASTSISPASASVSSPLSASASPSKLQSHSRSQYTNPNSSPRPLPSAPTTPIVVGIPFATEGDLSSTSLRTASASINSVFSSSLSSSSSSTIRPVFDSPRLSSSAFSSSTTTSRAPSCHRHLSEDPLVPSNRPPSAATSLSSPVLSSPTSKSESRRYSRDKLSENEPDFSPSSITIVDPESSTQRMVGGLRQVLHKPQTLHTDGLELSSPTVARFSVDAQPVLAGISAPGCRDAYTTDNKTAAAYKRSSVSTLVANPTESSTASAYPDLHEKASFQSETTLSETSNYKIYARSSSPPIPDVEDTLSLAPSLDSNTNVQILGHSSPPESVAASITDDLDLTILYSDEEDNFIVHNVSELAPSSPPNSPPLSPSTFARLQPEFSQESLRVAPLRPDVKVKITPASRPLSASSDSNETLRHAPSAESLSSAYSLETAQSLMATPAALYIQRASILNISSRSGTATSGSASTSTQSLLNSDSMSQQHYNESWNRYSTASTVNDEANNTDIPNSGPSLIISPIQAHPHKWSDQLSTVMSESEPSTTVPNSPVSRSNSMASFANSHAGRLSIGHASSVNSRRMPSISSSIAVNLESGAGSSSWSHSRSNSASVERPQPTHQRSPVLQIIQHVDEHGDGLGELNTLQSRPSRTRLGSIFSNMSSDRGLHSSSSSRGNSNLSPSSIPTWARLYYGSGERRFLSPTSEWSEVGDSRPGSRQSSVAGQRPSSSGEPIEASQTRNTHVRRFSIRAQIRKQTSSIWSPHLRQDRRTIMNRYSSMWDPPSVAWSSGSGILGRRNIQVVSFILGFIFPFAWMVAAFLPLPQSTSSIKVMEEGRNRSGDISSINEPIIPSQPQFDESYHLRMLEAARWWRRLNRYMSAVGILVTGAVISLIIIGVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
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                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
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        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6X3</accession>
    <name>A0ABR3Z6X3_9PEZI</name>
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    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
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                <person name="Spraker J."/>
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                <person name="Buitendag C."/>
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                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
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                <person name="Gasser K."/>
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                <person name="Duong T.A."/>
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                <person name="Wingfield B.D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
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    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
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    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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    <dbReference type="EMBL" id="JAWDJO010000076">
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    </dbReference>
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        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF15612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="640" mass="71102" checksum="84612ED8D99978CA" modified="2025-10-08" version="1">MSDDSSDLSSISSLSPAPSDSEPETIDQNKKGILKFFKTTPKAKSKPKAKAPSKTLSKAQTKPKPKPKSQSQSQSQPQSQAKPKQKKIIVASKEPSPPLRKREPSPPHEYVFADNPDIAFIVMFRARFNDIFSAHLATFGPQEFENDITDFFPGNRVEGFLCALLVLILNRKQDVKPGHYNRALEEAVSTHKNQWPKSWEGKSPVSGSNTFQTLAPSDKLILLRTLIHWALASSESIRTLVAKSYKNRHDEDRAIPLSVQAWGSDSDKRRYFLIEGRDGTSFRIYRESNFQGLNRTWWSVADSIDSLKALATSLEEKDGGPKAKSLAHSMRMAIPRLEESEEKRRRREYRLKTKERFLRPDPAHSLYEGRTRGKRVKYTFSDEEDVFTDYSARRSTRNTRNHTPEDAQIPVQHSRSTRSTRLNPDAQLSGTESAPNDSREPSVGANGRPRRQAAQNQGSKRKSLHAAELNVSDDDDQSIPEADDGGEHIPDESNSEDEEEFAGDDEMGDDEMGDDEMGDDDEEVVRESKNKMAKAKAAVEGPDDVNNLDGLLSPSVDSNGKDHGTTRSDCQEVSVTNSLETPDESPLGNRQTPEPEVEGSKIKITLKSSASASKRATSLAFRGSPDKPHASMVTSPGVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z753</accession>
    <name>A0ABR3Z753_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Glucose-6-phosphate 1-epimerase</fullName>
            <ecNumber evidence="3 5">5.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_002963</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the interconversion between the alpha and beta anomers from at least three hexose 6-phosphate sugars (Glc6P, Gal6P, and Man6P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 6-phosphate = beta-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:16249"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58247"/>
            <dbReference type="EC" id="5.1.3.15"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the glucose-6-phosphate 1-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.15" evidence="3 5"/>
    <dbReference type="EMBL" id="JAWDJO010000063">
        <property type="protein sequence ID" value="KAL1896047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09020">
        <property type="entry name" value="D-hex-6-P-epi_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025532">
        <property type="entry name" value="G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11122">
        <property type="entry name" value="APOSPORY-ASSOCIATED PROTEIN C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11122:SF13">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE 1-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016020">
        <property type="entry name" value="PHexose_mutarotase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR016020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1896047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="313" mass="34037" checksum="4F4DEAC852E630CD" modified="2025-10-08" version="1">MERSRKPVALARTPGLPPQPVVNITHDNTRVSAVLPTGESVEVLLHGATVISWKDATHKEKLWLSEGAKLDGSKAVRGGIPLVFPVFGTRPDHKETSKLPQHGFARTSAWDYLGKSTSETEGSSVKLDFGLSSESIPAASKALWPYTFGLIYSVTLNRESLTTSLVITNEGGESFDCQMLLHTYLRIDDIDKTDITGLEGAEFIDKIDPPPTQTQAGAVTIAKEVDRVYTPVGGPSTPIIVNEAGEESFRIVRDKLPDVVVWNPWTDKAAGMADFEPKTGFRSMLCVEAGSVREWTRLEAGDVFEGSQTIIIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z763</accession>
    <name>A0ABR3Z763_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arginosuccinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_002984</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000064">
        <property type="protein sequence ID" value="KAL1896007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01359">
        <property type="entry name" value="Argininosuccinate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.30">
        <property type="entry name" value="Fumarase/aspartase (C-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="entry name" value="Fumarase/aspartase (N-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00006">
        <property type="entry name" value="Arg_succ_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029419">
        <property type="entry name" value="Arg_succ_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009049">
        <property type="entry name" value="Argininosuccinate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00838">
        <property type="entry name" value="argH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814">
        <property type="entry name" value="ARGININOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814:SF1">
        <property type="entry name" value="ARGININOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14698">
        <property type="entry name" value="ASL_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00145">
        <property type="entry name" value="ARGSUCLYASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarate lyase N-terminal" evidence="3">
        <location>
            <begin position="14"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="Argininosuccinate lyase C-terminal" evidence="4">
        <location>
            <begin position="372"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00032749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1896007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="466" mass="52182" checksum="0B4FE68C32BCCEB3" modified="2025-10-08" version="1">MSETKPGENMLWGGRFTGGLDPLMVAYNESIYFDRVFYKQDILGSIAFARANAKNGIITQEEFTKLEAGLQAVKKEWEDGVFKIVPGVDEDIHTANERRLGEIIGKDVAGKLHTGRSRNEQIATDMRLWLRDELVKIEKHLVDFLNVTAARAEKEVDYVMPGYTHLQRAQPIRWSHWMLSYGFCFASDLERLREVIRRVNRSPLGCGALAGNPFGIDRDMMCKELGFDSLLWNSMGAVADRDFVAETMQWGSMLMLHISRWAEDLIIYSTGEFNFVRLADAYSTGSSLMPQKKNPDSLELLRGKSGRAMGQCVGLMTTLKGLPSTYNKDLQESVEPMLDHIKTVSDSIQIANGVLATLTVQPTKMAASLDPFMLATDVADYLVRKGVPFRETHHISGRLVALSENTGTPMNELTYEQVSQVDARFEKDIAAVFNYEKSAEARNAKGGTSKATVLEQISVLREMLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7Q9</accession>
    <name>A0ABR3Z7Q9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mitochondrial GTPase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">mtg1</name>
        <name evidence="5" type="ORF">Cpir12675_002649</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000054">
        <property type="protein sequence ID" value="KAL1896701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45782">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45782:SF4">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="4">
        <location>
            <begin position="213"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="17"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1896701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="430" mass="46959" checksum="6F04C0313A4D3804" modified="2025-10-08" version="1">MRPPTLAHPLAARCSSISQTITTSRASTRHPRNSPSLRPPCTRQFAHSPTRLSNSTAADSAPPTSPSSSQISATIPPVSTPSFTPRISFDTPQIRESYFIGHHRSALRNIEARLSDIGLVIECRDARLPLTSWNPVLENVLSNCNQRIVAYTKCDLISESPHNGNIQAALGRFHVSQPGSGKPIFLRKGMQATNLLNMLRDCAANTESLTGLRIFVVGMPNVGKSSLINMLRGQGMGAGGRSKVAPTANYPGVTRKLSSPVRVLGGKNRPQDNVPGEGVFVIDTPGVFIPYVADKEVMLKLAVAHGIRDGIVPYETQADYLLYKMNHWSPKLYEHFCPPTNDVMELLAAIATKTGRLSRASPGHEHHAAGWMVGQWRSGKLGRYPLEEVNKTTIQASIENLRDPAISLSQAKKLAKEARQEIIKARRKAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7Y9</accession>
    <name>A0ABR3Z7Y9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sister chromatid cohesion protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MCD1</name>
        <name evidence="7" type="ORF">Cpir12675_002897</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the rad21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000062">
        <property type="protein sequence ID" value="KAL1896190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.580">
        <property type="entry name" value="Structural maintenance of chromosome 1. Chain E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039781">
        <property type="entry name" value="Rad21/Rec8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006909">
        <property type="entry name" value="Rad21/Rec8_C_eu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006910">
        <property type="entry name" value="Rad21_Rec8_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023093">
        <property type="entry name" value="ScpA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12585:SF69">
        <property type="entry name" value="FI11703P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12585">
        <property type="entry name" value="SCC1 / RAD21 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04824">
        <property type="entry name" value="Rad21_Rec8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04825">
        <property type="entry name" value="Rad21_Rec8_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad21/Rec8-like protein N-terminal" evidence="6">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="Rad21/Rec8-like protein C-terminal eukaryotic" evidence="5">
        <location>
            <begin position="549"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="624"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="650" mass="71627" checksum="5E803485A89442F1" modified="2025-10-08" version="1">MFYSETLLQKSGPLARVWLSANLERKLSKTHILQSDLGESIEAIITPSQAPMALRLSGQLLLGVVRIYSRKARYLLDDCNEALVKIKMAFRSSGNNDLTTNLHAPTREALMLPDKITQYDSLELPPPPDAGWLLSQMEDPNATGAALGRKGRVSNRDINLQEDYSNSQFLDISDTLDEELALAPLDDIQLDLDFGMDIERPSKFNQTMELGRDAPLARSVEDDIFSVLDDARGGKEPLDMGREPSLALDIGDDTVRIADDEGDIHMRDDDFQFNIGEDPSVVPAGTSMAQLGRGRISESPLSDIDEDFAKEVEEEYTRHQQTDFYEPEEEQESVAVRRPAARVKKPKLILPDEETMLSSAHIKEQQAHHDNILRSQAFVPRDSHFASLIELQKTGYFSGSILHGKRTSAWSPALRGLLSMSAIRVPVEMKRKREHVESETEAENVKSPRLEFGEEEEFGMSIAPVAEETAIVEETVVELAPEEQNLDDVSLEREEISMGGPAFDETVAPLVHPAESGPVSIGTQHAVHILREIFGPDAEHDAEKRKESAVVFQDLLPEGRTSKADATKMFFECLVLATKDAIKVEQGPELGAAIKIRGKRGLWGTWAENEAGGEMAAQMGAEVEPVSAATPGPTATSFQPEVTPAVSVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8V3</accession>
    <name>A0ABR3Z8V3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Autophagy-related protein 14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_002662</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000054">
        <property type="protein sequence ID" value="KAL1896714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018791">
        <property type="entry name" value="UV_resistance/autophagy_Atg14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15157:SF13">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15157">
        <property type="entry name" value="UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10186">
        <property type="entry name" value="ATG14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="209"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="318"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="213"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="324"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1896714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="455" mass="50309" checksum="3E35BEA1E160D310" modified="2025-10-08" version="1">MAKDSFASRIDGASLKQEKFMSYDKLRSETEIACARTKTAKAAAAALRSQISIQREHMAAKKAFLEHRRDDLTAAGLGLEARRAHQMDETRRVIGDVRAEWANTADDLVRTRAFLCREAAKLFGPIRVCKPETPGKWAFEIGHLEVIDITNMNNYTPEYISTSLANVAHLLVLVAHYLSVRLPAEITLPHKDYPRPTIFPIESSYASPLPGSSIPNEKSPSACTSREPPPSPSESSVRVQPRPLFITKPLAMLYKDDPESHSAFIEACAFLAYNVAWLCISQGMVFSDRVTLDEATNMGLNLYTLLFSERPPILSGTASAASKTPTLLQPTDTQPSRTSKPEPNPDPVHGRFSHGTACNFLHAVNGFNISRMSKFPMARVIHDRLLTKLVTDLALPEWELLDTHEWQVEDAPEEADAVLVSATMIPEARDSNSTAVDGNINASPWTKVRGYGSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z927</accession>
    <name>A0ABR3Z927_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Histone deacetylase complex subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CTI6</name>
        <name evidence="6" type="ORF">Cpir12675_002650</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000054">
        <property type="protein sequence ID" value="KAL1896702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053051">
        <property type="entry name" value="HDAC_complex_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47793">
        <property type="entry name" value="HISTONE DEACETYLASE COMPLEX SUBUNIT CTI6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47793:SF1">
        <property type="entry name" value="HISTONE DEACETYLASE COMPLEX SUBUNIT CTI6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20826">
        <property type="entry name" value="PHD_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger PHD-type" evidence="5">
        <location>
            <begin position="120"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="130"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="239"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="452"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="562"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="683"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="44"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="141"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="152"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="246"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="257"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="287"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="384"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="452"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="473"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="490"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="518"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="562"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="573"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="587"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="618"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="700"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="726"/>
            <end position="736"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1896702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="768" mass="83391" checksum="BC7457696D75E6E0" modified="2025-10-08" version="1">MAPLSPRRSSRARIPNNNLPTNPVSSAAAIASSRPERTTRSNRPSSTKSTPSASLSSESPDDYDDIHILRSSRRRGPDDGSSTPTSKSRPSRRDNTTSITVANMANHNNEEIQEDDEAVRCVCGFDDYPGPPPLPAPQVSDAVSTPSASTKRSRERDSRSDSEFINGIEVNEDVSGFYVQCDVCKVWQHGACVGIMTEESSPDEYYCEECRKDLHKIHIATNGQRYSHYTYATIVSRSASRAAVGSKDREKDKDGTSRSGRLSTASQTAKRRSTMNSRDAAYDEEEELRRAIEASKEDAPVVETTDNSSRRLKRGRSHSEDSPSISPPTEKSGPSPDDSEDSSSARNVKRSRQSRSQRENLERQQKERQRQDAANKRRVRADRRRADGSTWRDSEKDDYSADSKEPDEPSAKAEAVAKDIVLPDNAEPASIAAESDIIADVEASVATATTTTAVADADASVNETSQTPDKATTRTTPPSTTAPTETSMDFLEKKPSDKRIIEKAEPETEKAPIKTTEVSSAAASPAPSIPAVIKTPDTPLTTELALPTCAPTPISEVALAAAPATAPAVSVKKTSKTSKKGRGRNQYTRDRDEIEDSPVRSTRESRHKSAAAAAQQDNYSSHSSISNGHNNNGNGTGARGSRHTHDAKSYKSKSSVGKLSIPELKRRSAAFLDFIQKTQLELAAEATPSRSGSSSDDEGREVSLEERRVGDGNGGNRGREREGTAVPSTRQGTPEPSTARKDFGDLSCGEMMDVLTRDLVKWQNQYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9E0</accession>
    <name>A0ABR3Z9E0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amine oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002707</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000055">
        <property type="protein sequence ID" value="KAL1896685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.405.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046972441" description="Amine oxidase domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="Amine oxidase" evidence="2">
        <location>
            <begin position="46"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="476" mass="52358" checksum="9675E7FC83B6EF74" modified="2025-10-08" version="1">MTVISSIVVLATTLVAASGAATEGLHTSVVTRDVLIVGGGSTGTYAAVNLTDAGYSVAVVESDSMLGGHVSTYVDPVSGRAADYGVMVLSDEPVVHNFLTRLNIGWVPIEFDGSNIDFFDFKTGKPNHDYVQPIPADAIPQYWNLLLKYPYLAGDGIVLPDPVPDELLCNFGELIEKYNLSGLSRVFFQWGQGFGDILKLPALYALKYFSQSFILGIKGENFISVSTGNFQDIYDNAAAVLGDSVYYQSRVTYMDRGRVDPEGYTRAVVSTPSGKVIIRAKKILMTIPPLLNDNYLNPFQPDSHESSLFSQFSHFNLWVAAIKDSSLPPINLQNVSPGINSTLYSLAKLPDTYYFRLTPAPGVWATSFGSLNDEERTEDSVKGDILRVLEDLRENGGYANDSSSVSEAEIVEFRNHSPYELTVPVEAIQKGFYRDLYELQGYQNTYWTGAAWNAHDSSSLWKFTGRVLESLKLGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9G4</accession>
    <name>A0ABR3Z9G4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcription initiation factor TFIID subunit 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">TAF9</name>
        <name evidence="7" type="ORF">Cpir12675_002410</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000047">
        <property type="protein sequence ID" value="KAL1897228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07979">
        <property type="entry name" value="HFD_TAF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003162">
        <property type="entry name" value="TFIID-31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051431">
        <property type="entry name" value="TFIID_subunit_9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48068">
        <property type="entry name" value="TAF9 RNA POLYMERASE II, TATA BOX-BINDING PROTEIN (TBP)-ASSOCIATED FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48068:SF4">
        <property type="entry name" value="TATA-BOX BINDING PROTEIN ASSOCIATED FACTOR 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02291">
        <property type="entry name" value="TFIID-31kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="202"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="253"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1897228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="264" mass="27544" checksum="6E3A9F380EC8D8B9" modified="2025-10-08" version="1">MASVPAAQTNGISIPGISMTSDPTASGITVNGASTTNPPDDALADGNPGGDGNNTTKPASAPRPRDSRVIELLLTSQGVTSYESRVPLVLMDFAYRHTSAVLSDAIHLSNDPISTGKQASSAAAGADPVVSAAAIKLAIAARLGYQFRGGGAGGGLSKEWLQELARERNKVALPKVSQNDWAVRLPSERFVLSGLGWGLADRWEEDGESSSGDEDEDDEMEDAMDMLGKTKEEDVGGDGVEGGTLEDVFGQDVDMDMDEDMETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAB8</accession>
    <name>A0ABR3ZAB8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Derlin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_002801</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the derlin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000058">
        <property type="protein sequence ID" value="KAL1896464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007599">
        <property type="entry name" value="DER1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11009">
        <property type="entry name" value="DER1-LIKE PROTEIN, DERLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04511">
        <property type="entry name" value="DER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1896464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="255" mass="29285" checksum="2020A2CD07DAD75F" modified="2025-10-08" version="1">MDPAMGGEGQFPLEEWFWNTPTCTRWWTTATFLTSALVQFGVVSPFQLFYSYRAVFYKHQYWRLVSSFIYFGPFSLDLIFNVYFLQRYSRLLEESSGRSPAHFAWLLFCVMASLIAMAPVISMPFLGHPLSSTLVYIWSRRNPNTRLSFLGVMVFTAPYLPWVLMLFSLVVHGRVPKDEIIGVVIGHVWYFFNDLYPPLHHGQRPLDPPAFWCRIFDGRPTPVNENEAETEQPPTGNIGDALPGARPGIAGREIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB41</accession>
    <name>A0ABR3ZB41_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_002438</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000047">
        <property type="protein sequence ID" value="KAL1897255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027842">
        <property type="entry name" value="HAM1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045967">
        <property type="entry name" value="HAM1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31138">
        <property type="entry name" value="CHROMOSOME 19, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31138:SF1">
        <property type="entry name" value="PDZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14613">
        <property type="entry name" value="HAM1_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19343">
        <property type="entry name" value="HAM1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HAM1-like N-terminal" evidence="3">
        <location>
            <begin position="12"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="HAM1-like C-terminal" evidence="2">
        <location>
            <begin position="658"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="domain" description="HAM1-like C-terminal" evidence="2">
        <location>
            <begin position="809"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="869"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="902"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="915"/>
            <end position="931"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="931" mass="105775" checksum="D3535CF81F71B6C9" modified="2025-10-08" version="1">MKSPSSWSLGHEKRVNRPTDVNVKDSDVARKLQLYGIATAFRAGKCPSNDQIDVCINSLLSQPFIKKAPPNVSRDGRILIADLCALIRCGQSLLLSKNEGNLLQNAWWHLQGVDRHDLRVPGRPVSRLANKADVSKALRSLNVLANLVVTNGQFRKLLKDAGILFRDIASDAATTASRLFRPKAEDLAQIDEPAEDNVWYSEPDISGFRTRARNMIGQGRLEACDLTDSLERAGENFSVPQSPRRRRLGGKEIKKKAIKIATRKPTDKAIKRQDSRKTKSRKEQMRKDAKEYLQRKVPKSRQESIIFRLKKILQECQHNGDYRVAVTALLDLGERYKHFALNLAEDSQETLRESHDEAPIDLKEAEYEIKLLIERFAHGTSLDGLIEAVHSMCSAAHEDEDLLYWFSDMNGFIRSCLLNPGYILEDDCSDDWEELYSIGHSLLRTRYKQQTDRIADEIKFIAQQFDEDEQNAAFAKATKKVFKSLGEGEDGHIQFKPHLMKDLFEVFLPSLLSKISYIPLPRIEFSSADFDVIVENLVLESDNFTPNTAQWRSETKINWGRKSLTQQSQLKNKNALHQVCEIFLSGIQFDLRGVAYHVNRKTGFLPMCDSGIADLLLPGEGLAVKITLAMASASEEKGHAITASNSEYKWFQLQTVSVDMSRLEVNIVESTHKVLHHIFRPLVIRELRNVLKETAERLIREKSSQLDALLWKIHQNAVAYTTRARELNRHPPGKLRRYAKATRYVFRMYRAHRRREHGRESENYSLADSTTGRRSLNMALLSPAIPHIEPAKYGVPAGERRTRISWTVMENSLFPDIKLPDAKGTSVSFKAAEYKELAHKGERWTSPVFSIGSASRSVQLPAPTRVMRKTPIFRSRTVEEDDENEHRDEGEAGAESEEQQQTRGANPRTATGTPWEDDDGESTMETFVDCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB61</accession>
    <name>A0ABR3ZB61_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">SRP54-type proteins GTP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_002401</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GTP-binding SRP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000046">
        <property type="protein sequence ID" value="KAL1897296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14826">
        <property type="entry name" value="SR_alpha_SRX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="entry name" value="Signal recognition particle SRP54, nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007222">
        <property type="entry name" value="Sig_recog_particle_rcpt_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134:SF1">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04086">
        <property type="entry name" value="SRP-alpha_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="Domain of the SRP/SRP receptor G-proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRP54-type proteins GTP-binding" evidence="9">
        <location>
            <begin position="611"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="138"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="161"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="191"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1897296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="640" mass="68843" checksum="A2CCBCD6E17A1BF0" modified="2025-10-08" version="1">MLESFEIVTTAGVVLWSRAFNKTSPSIVNSFITDVFIEDKIPGAKTDTGSAKTNMAYKTDHHTVKWTLVKELGVIFVAVYRSVIHLPWVDSLVDNISTIFVSLYEDKLKRPNTTIVNCASFEKYFDQQLDELEQVAGPAHTPATGTPLAFDEFSADDSMPSRPTTPMITNTTASTAIAGPGGKLSRRQRKAQAQSTVQSGNESSSSTRKTKSAVSAKDTKKKGRKWDADGIATEDDDVQLDYSAPGDSSALEACGPSANLETPDASTWGTTTAKGQFVLRDLGDEVHDILALAKSRKSEKAEAAADAQAGARKGGLVGTGLSTLGDMFRNVVGGKTLTKADLEKAIKGMEEHLLRKNVAREAALRLCEGVEKELVGVKTSTWESTQDRIKLAMEASLTKMLTPTSSLDLLREINSVTAPGMTSLAKPRPYVISIVGVNGVGKSTNLSKICYFLLQNRYKVLIAAGDTFRSGAVEQLAVHVRNLQELTLREGGQVALYQKGYGKDAAAVAKDAVAFAAQEGFDVVLIDTAGRRHNDQRLMSSLEKFAKFANPDKILMVGEALVGTDSVAQARNFNASFGAARSLDGFIISKCDTVGDMVGTLVSLIHATNVPVLFVGVGQHYSDLRNFSVKWAVEKLLTAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBH9</accession>
    <name>A0ABR3ZBH9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Small nuclear ribonucleoprotein G</fullName>
            <shortName evidence="9">snRNP-G</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SMG1</name>
        <name evidence="11" type="ORF">Cpir12675_002117</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Plays a role in pre-mRNA splicing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000038">
        <property type="protein sequence ID" value="KAL1898030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01719">
        <property type="entry name" value="Sm_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044641">
        <property type="entry name" value="Lsm7/SmG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034098">
        <property type="entry name" value="Sm_G"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553:SF2">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="3"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1898030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="81" mass="9031" checksum="878FDFBD33E41F3D" modified="2025-10-08" version="1">MAPAQPELKKYLDKRLFVQLNGSRKVVGVLRGYDVFLNIVLDEAFEEKDGGQKVPLGMVAIRGNSVVMLEALERIGGDDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBP9</accession>
    <name>A0ABR3ZBP9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DNA-(Apurinic or apyrimidinic site) lyase</fullName>
            <ecNumber evidence="10">4.2.99.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">APN1</name>
        <name evidence="10" type="ORF">Cpir12675_002044</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AP endonuclease 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="10"/>
    <dbReference type="EMBL" id="JAWDJO010000036">
        <property type="protein sequence ID" value="KAL1898096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00019">
        <property type="entry name" value="AP2Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00152">
        <property type="entry name" value="Nfo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001719">
        <property type="entry name" value="AP_endonuc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018246">
        <property type="entry name" value="AP_endonuc_F2_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00587">
        <property type="entry name" value="nfo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002199">
        <property type="entry name" value="PRK01060.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21445:SF0">
        <property type="entry name" value="APURINIC-APYRIMIDINIC ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21445">
        <property type="entry name" value="ENDONUCLEASE IV ENDODEOXYRIBONUCLEASE IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00518">
        <property type="entry name" value="AP2Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="Xylose isomerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00730">
        <property type="entry name" value="AP_NUCLEASE_F2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00731">
        <property type="entry name" value="AP_NUCLEASE_F2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51432">
        <property type="entry name" value="AP_NUCLEASE_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylose isomerase-like TIM barrel" evidence="9">
        <location>
            <begin position="114"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="401"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="401"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="418"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1898096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="446" mass="48810" checksum="927023942A55A3F3" modified="2025-10-08" version="1">MAPRKSTRAATIKSAKRKAESLADSEIKSESESESKPNPPKKLKAAPTQAPVKSELLSLPVKSRSKPKAQAKTKNADGMIPLIERTTVSTLKKAMYIGAHISAAGGVQNAPPNAVHIGANSFALFLKSQRKWNNPPLDPTARDGYISATKHSHYNSCKHVLPHGSYLVNLAQTDKAKGDQAYASFVDDLKRCDQLGILLYNFHPGSTGGESMDSACKRIAERINAAHKETKTVIPVLENMAGAGNVVGGRFEDLKMIIDGVEDKSRVAVCIDTCHAFAAGYDIRTAEACKRTFGEFDRVVGMKYLRAFHLNDSKAPFNSNRDLHANIGTGFIGLRAFHAIMNNESFCDMPMILETPIDFKDANGKSVENKQIWADEIKLLESLIGADTETDEFRQLEEELQARGENERAKIQDQVNRKSSKSGVKKAPAMKKPRGKKKVESDDDSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCL0</accession>
    <name>A0ABR3ZCL0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nucleosome assembly protein C36B7.08c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_001928</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the nucleosome assembly protein (NAP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000033">
        <property type="protein sequence ID" value="KAL1898383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.90">
        <property type="entry name" value="Nucleosome assembly protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037231">
        <property type="entry name" value="NAP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002164">
        <property type="entry name" value="NAP_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11875">
        <property type="entry name" value="TESTIS-SPECIFIC Y-ENCODED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00956">
        <property type="entry name" value="NAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143113">
        <property type="entry name" value="NAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="227"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="242"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="307" mass="34885" checksum="EA139977E1FB08BB" modified="2025-10-08" version="1">MSDDKTTVSEIFFEELADIELEFEETENAIIRMQVELQAGLYEKRHELINKIPNFWSLVFEQAPADIDEYIMPTDAAALLSSLVSLKVNHFEIEGGDSGMGEARSIKFTFEFRENEYFNNTTIEKKFYFRYGKGDWSGFVSEPVTIDWKEGKDLTEGMLDLAKKVYDDDMAHEAAGTAKADTPTDNEKKLITKLENSAAGGVSFFAWFGYRGRRVTDAEHKEQKTILAARRAGNAPKKAEDEKNEAEEEEDEDDDDDHEYDIFVGGADLAICLADDLFPNAIKYFTQAHELENMSDSGFETEEEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDA9</accession>
    <name>A0ABR3ZDA9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_001827</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000031">
        <property type="protein sequence ID" value="KAL1898623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="30"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="235"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="322"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="406"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="132"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="251"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="275"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="345"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="416"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="446" mass="48993" checksum="ADD3E1C83BED0B59" modified="2025-10-08" version="1">MIVGFAVIAFVMITVSVFCFMRNRKRKARDRTKYQQAPLSEPSDTRRPNTSSIWNSLGASAPLTTTAVNRATSIRSIMTLPAYQPNAAENERVLGVEGERDGVDVILELPTESDIENMRENEMESLYQIRLARRLEIQEREERRRLRREARQNNDPVALRNLRQQRQAANERDLVAALREEHERIKAQRQRAAPSVAYADVGIARHDGTRVRGTSMESERVGLLSDAASISASILSPRRTRERSGSALSVDSDTARPASRSRADSALTTPAPFTHETNNSDSPRTSINASRRNTATRSSNTQLSPPEYEDIPLTTTVTSHSVNTISSVIPTEPPPTYDGSRIATPESSRSSSPQVLTLGSTPSLHETSPTPSVRAPALGQTTNVQEIRIEVNSSLPPQSSVLPFRLPSLNLGDNPGISTQGSINSNRTTKNADGPSDRKHVNQTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE74</accession>
    <name>A0ABR3ZE74_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-tRNA hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001801</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000030">
        <property type="protein sequence ID" value="KAL1898694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="293" mass="32108" checksum="F5CA657E8D4AA27B" modified="2025-10-08" version="1">MRYQTIALALPAVAQAQDSFFGQYKAKFQNVIGQFTAIIPSPSAVPETIEEVVPEVLLNKKVLEPLALPSWKDTLYEPVEEDTKTPEQWWVFITGGNKTCQGLCGHAESMFNETAAKFASMPSAPHTAILNCEYEPILCNAWACSPGFIWAFDMLPAPANTAIHTHRLNITAVSVDDLLELQAQGIPKVTPDSKDSETTSESESESEPRTVSKPQWSVVDGFFHPLDGPLVQYNLQLPFAYAMWAINLVPQWSIMMIVSFATRLFINRRLGNRNQAHGTAGADAAVAAAAPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEA8</accession>
    <name>A0ABR3ZEA8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein OPI10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_001665</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OPI10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000027">
        <property type="protein sequence ID" value="KAL1899005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048364">
        <property type="entry name" value="Hikeshi-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008493">
        <property type="entry name" value="Hikeshi-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031318">
        <property type="entry name" value="OPI10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12925">
        <property type="entry name" value="HIKESHI FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12925:SF0">
        <property type="entry name" value="PROTEIN HIKESHI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21057">
        <property type="entry name" value="Hikeshi-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05603">
        <property type="entry name" value="Hikeshi-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hikeshi-like N-terminal" evidence="2">
        <location>
            <begin position="10"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Hikeshi-like C-terminal" evidence="3">
        <location>
            <begin position="132"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1899005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="188" mass="19702" checksum="DA3DB28C128F42E0" modified="2025-10-08" version="1">MSGALFGVIPIGQAIMTAPSSAISETSLLYAVNNCESVVVSLIPGASLPAQTAAAIYVTSTSDFTLASATGQTPDFKLSGAVGPGKESVFIDIKPYLSTEGAVIGISIEAADEVAGKMQQMPLLKSKPGRETTISLAQAIISNAFDFMASFSGMSGPDGVEVVPLKAFENWWKKFESRVRSDPSFLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG00</accession>
    <name>A0ABR3ZG00_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000021">
        <property type="protein sequence ID" value="KAL1899596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38119:SF1">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38119">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="396"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="528" mass="59409" checksum="CD671F9238B65CED" modified="2025-10-08" version="1">MGPPVGSLKLGTCSELGGSYPMHPIASTVSRPLDHRPRRSRRSHANGSSYLPQNEFPIFSQSGDVEIIIGLGSNSSFQNRYLLHSHTLSRFSGFFEASLRPEWNLSASEPSQFTHTGNAGDARSPTNHPPKPMWRYELDRGDNMDEVPMLVQKKATKPAPPPIFGAPPSLASVSNGRTKTSLLPQAAQSTANLFQAVTPFGAVDPDDDNMTDTLSFQDQDLMRDYDNMFRIFYNYTPNIDSISIADAYVQCKSLLHLADLYDALDVVGPRVDHHLLQFQWRLWKQVAKYPISYLRLGYMARSKLIFLEALIHVVGQWPAGERTLRASMPNSVLEIIEDKVSDLEEQVSRVESRLFRLTLYTNTGEPVTPATSYLDWLAVSFFRQWLVMETTLPFQPPPHDGRRHHNSHHDNAPPSIPPVQSLGRVYRILGAHRRSSSAYLSRDECKRFLKLTPELYSRENLRRFEKSVNELKTMASDLVQPLMDSDLELSMASGPSSAGAVSDRMNDDISYLTCTQVGNQDIPWSIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGK9</accession>
    <name>A0ABR3ZGK9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Anaphase-promoting complex subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">APC1</name>
        <name evidence="7" type="ORF">Cpir12675_001502</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the APC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000024">
        <property type="protein sequence ID" value="KAL1899309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024990">
        <property type="entry name" value="Apc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049255">
        <property type="entry name" value="Apc1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12827:SF3">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12827">
        <property type="entry name" value="MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12859">
        <property type="entry name" value="ANAPC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Anaphase-promoting complex subunit 1 N-terminal" evidence="6">
        <location>
            <begin position="29"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="342"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1795"/>
            <end position="1815"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1998"/>
            <end position="2020"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="2045" mass="223761" checksum="8904FD3FA383CB24" modified="2025-10-08" version="1">MAQVTSLGLHQPAGLQHAISEHLLPEDASPSAYTWDVFLDDTGANPVQDELLVTASAVVWSRGNIFCKTFNFSVEKEDIRQALLTYFPTKTEDPVSTSASRPPPHTDTNNPVNHKHVPKLARALVVFLKTQAHIFFLSGASHIVHMPFEVETARALPQGLLIQRKNQNDAAGGTAAGIRFPRVPPNSFTSSQPIFSLDPPTPTRQSFSVESLGKPATLPLRLGSTLGNMNQSSINAPLSHWPRLVTLLDPLLELGLVAVTAPEPVVADKRKAMLPLRPSCLDATEEILDMHVVSSPQLRGCEPLLLAVTVNRESSAYSIWRVRYLPTVDAFIKTAKTTMPSKVDRRRSSMAPGYATSTSAAGGPSTDVKTPVRSGFRESFGVPLPGKRTRKATEKEKASYHHQQQQHQVNFVASLEKERDPVITRRQSKRLSSLARVDMPASQERSVFAESNQIKRLESFHNHGRLSGAHSYNQSIHPSLNSLLDVNVDSLLEDMRVGADFEASGLYNMGLQDHDFEGLAQELSFSKIKTIPASNLTMASIGYSSDKAPASLPRIFNIVHPPSHSHRNGGISLMVVIQDSVEHQLDLVTLKFNRHARGAGSLDTLTLGGVEVRRAPGVVDSCKLVDGDVDMMLILSERNEGGLELSIQAPWSKPTTVSVPVLIMDHMRSLQYIGQVDDKTAVDSLPRKAGLSINEITGFRPHQIAGVVDIIDKTGRMHQLSIRLQPTNRQVRDILDVCRVVIADAAGETIICGWWQVMQWVQTENINVADREWSALTVLLLSMFLRLSTTATTLESSSSSSSHSHLQSKYGELRQKASKQKPTNSQSNWSAMQMHVNPNAAAVSSWLTSPAWSWAFDSVVAASDNKAESFIATHIRYSTRFLASATGVMMLGPNGYLPTASGLHEERRLFAARNILVGIHLLVEEQKLDISIPETGPNSRAGTRVLLAQISRWMGWKALSTNSGYEMCIQEPLDAAFDNEVTLSTPVPCPEANLCVLTWIQTRLEGDRTATFPGLIDVLETAQAPSSSYSTNSALQEFAASLTPRTTQFRAFFNLLRPNASFADTVEAMYKAGFSTNVALETLPEAVLTTLKDPIAMCQAFPPSAWSKGLLMLVNRSDIGLLLDSHRGKRAIQPQGQLRRQHNKAVSHAATWDMQLLCKNTEEGPGLAQEDTDAAAAQHQAIVRNLFRQDRRFNDALEMMSTVRARTITLRPQPDWSESVYLEKQKDMVARVALSTLAIPAGRGLLYYGLRFPLPTQKTNIIGFNLNCIVKPVNVTVGVDRALFTEEKVCWSFFHQGAAAGLSISPKAQGIDNSWILYNKPGQDLSNRHAGFLLALGLNGHLTNVAKWVSFKYLTPKHNMTSIGLLLGLAASHLGTMDSLITRLLSVHVTRMLPRGSAELNLSPLTQTTGIMGIGLLYYNTQHRRMSEIMLSEILHSPELDGETDSEEAQANSDTLRSEGYRLAAGFALGFINIGRGADLKGLHDMDVTNRLLTVATAPKRVELVNVLDRSAAGAIMALALIHMKTEDALVARKVDVPDSIIQFDYVRPDLLLLRTVAKNVILWSQVQPTMEWICDSLPTAYHSRANLATTTRLTSSDLAFYSILGGLCFSIGLRYAGSGNLHARNLLVRFLDDFGRLLNISKGRSGTDLGVSCYDEELARHTLRTCQDITSLSAACVMAGSGDIMVLRRLRSLHGRTDPDIPYGSHMAAHMAIGLLFLGCGSMTLSKSNLATASLLVAFYPVFPATVMDNRAHLQAFRHLWVLGVESRCVVVRDVATAEVIGIPVSITLRPNAGLPARNNPRSTAGLTGPPRPPTNETIVKITPCLLPPLDEIAIIRTHGGPMYWDTEIDLMANPNMALAFTETRTIHLRRRPAADAPFSDFASASSPALVQTDNLNPGPLASLSGGSTDDIALAGNLSWLFSLDGLKHLSSADRTMVLDTQAGNGDGAAGSLYPSAVDSRLELENTAGHSRDEMLGLRLLFQWGHVRDAIRMRELDKDPAGSEDPNLSNHEASRKQKEMEQAEWWVKDEVVQALKAQVIAGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGM4</accession>
    <name>A0ABR3ZGM4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000028">
        <property type="protein sequence ID" value="KAL1898948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="383" mass="41361" checksum="96F4936174A2132E" modified="2025-10-08" version="1">MSHTPIHSRHASITQGSPFNSPSQNRNSSLLDPTTPNRSSFAQRDSFDIAEIGGSAMGSGSGLGNLADELADAFDESGDDEYYDDDDTPQVDSELHDGNNDIQVEHDASESSDRASPNNPESKTNNSMLNLPSPNRKGHRRAGSEYDGSEFGSESDLETPGTMSVGLVSKMDAVESLARRGIENTGGPADGVFARVTESLKDLGSQAGVEGGATRLITAHSALTTHLSHQTRQLHNLTFPLLSPLATPSDPQIIEDMIPLLVSLSDTMPRPSAQALSAITALHAMSSDLVQTLNYLTDTLHMSRQTTTTATRRLKSTRELVAEMKHEDELREEGETWLARGNWGQRLENRECASVCGDVVGGFEKVCEDWRARLLAQAESAQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGT6</accession>
    <name>A0ABR3ZGT6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dienelactone hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_001762</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000029">
        <property type="protein sequence ID" value="KAL1898759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630">
        <property type="entry name" value="DIENELACTONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630:SF44">
        <property type="entry name" value="PROTEIN AIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1898759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="234" mass="25744" checksum="374046D04B908870" modified="2025-10-08" version="1">MACDCANCTWGSLPKVNNLTGTIETIAGILCYVARPSDIGYCPYTSVREPIGVIVILPDMFGWEMAQTRALADHYAQRIPAVVVVPDLFNGLSLKLNRVGVAGFSYGGKTAIRLSHGPLWRYSHKAGFLEPLVDCSFSAQPPHVSLRDLEKVQLPLSVASSHHSEKPLGYIYSADRVLNCEKDNCEFVVYMDAGPGLGIRADPGEKMRVRESVLAQHQAVLWFTRHLPAKEFAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH28</accession>
    <name>A0ABR3ZH28_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peroxisome assembly protein 12</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Peroxin-12</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">PEX12</name>
        <name evidence="18" type="ORF">Cpir12675_001195</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Component of the PEX2-PEX10-PEX12 retrotranslocation channel, composed of PEX2, PEX10 and PEX12.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the pex2/pex10/pex12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000017">
        <property type="protein sequence ID" value="KAL1899971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017375">
        <property type="entry name" value="PEX12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006845">
        <property type="entry name" value="Pex_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12888:SF0">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12888">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 12 PEROXIN-12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04757">
        <property type="entry name" value="Pex2_Pex12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="18" id="KW-0436">Ligase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Pex N-terminal" evidence="17">
        <location>
            <begin position="25"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="325"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00034505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1899971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="457" mass="51383" checksum="00355D0AD26DCF51" modified="2025-10-08" version="1">MEFVTALRGQFDPQKPSLFELLSEQQLSALLPPTLRYLLVLCAQRYPRYFLRLLNSFDEAYALAMVVVERFYLRTRGGSFTENFYGLKREKATATDIPRAMLGAAGVARDTLRLQARDIWANIAVSVGAPYLKRRLDEDYEINAPRALLGLAYTRMPCNPTLRQRFVHYYRWFLRNVYPSANAAYGFATLAFNLAYLFDRSRYHSPLMWLVGTRVRRMAAADYQALEQKAAAASAAALAASGAGADTAMWQNIRRTLTSPRRMGQSVLAGLSMALPASIFALKFLEWWYASDFAKQLTRNATDALELPPPVLPVVRRFRALNSRKSMEEARKTSGSYDRPTEDDAGADEEARDRPSVDEAPVARDSLLPIFTVPAPKNSALCPICEEQVQTATACQTGIVYCYSCIHRWLEGEHQRQEAFMLGDGGRQGKWENGKGRCPVTGRRVLGSTDGLRRIMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHX8</accession>
    <name>A0ABR3ZHX8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pre-mRNA-splicing factor CWC24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ATG3_1</name>
        <name evidence="11" type="ORF">Cpir12675_001333</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the CWC24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000020">
        <property type="protein sequence ID" value="KAL1899655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16539">
        <property type="entry name" value="RING-HC_RNF113A_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039971">
        <property type="entry name" value="CWC24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12930:SF0">
        <property type="entry name" value="RING FINGER PROTEIN 113B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12930">
        <property type="entry name" value="ZINC FINGER PROTEIN 183"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="4 5 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="10">
        <location>
            <begin position="190"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="280"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="190"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="328"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="40"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="71"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1899655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="358" mass="38823" checksum="6956A583F9B67B57" modified="2025-10-08" version="1">MNTSESTEANNLPTALFKKRGPKGKNLRKRPATPPPASDSDLDSGFESTDDESTGQRLKRRKKNRIAVVAASSSTTDPNSATNTASVTSDLNATVFAADRSVAITDVNDATKQRDWFDEPSFATAAVSKNASPNKSIAQSSATTASTSLNSTYKGLANQTRFIEKNPNAPNRTYGPMKAATNIRTITVTDYAPDVCKDYKQTGFCGFGDNCKFLHSREQVMQGWQLDREWENVGKGKKNMVGTVVANVAERTAESVNRGMGTADIDAAEAALLEKIPFRCIICKEDYKAPIATRCGHYFCEGCALKRYRKDPTCAACGVGTNGVFNGAKKLSRLLEKKAAREEEMKKKAESENEAAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI17</accession>
    <name>A0ABR3ZI17_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAD synthase</fullName>
            <ecNumber evidence="2">2.7.7.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">FAD pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">FMN adenylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">FAD1</name>
        <name evidence="14" type="ORF">Cpir12675_001157</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>FMN + ATP + H(+) = FAD + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:17237"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="2.7.7.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.2" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003919">
        <property type="term" value="F:FMN adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23948">
        <property type="entry name" value="FAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23293:SF9">
        <property type="entry name" value="FAD SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23293">
        <property type="entry name" value="FAD SYNTHETASE-RELATED FMN ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoadenosine phosphosulphate reductase" evidence="13">
        <location>
            <begin position="54"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoadenosine phosphosulphate reductase" evidence="13">
        <location>
            <begin position="136"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1900050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="256" mass="28604" checksum="EEBA4CA9170B21A9" modified="2025-10-08" version="1">MELREACCQMHGQVEAFLARENTAANTVLAAVQAQTRKSLAIIDEALQQYSFDQLALSYNGGKDCLVLLVLILASLHKRYAALPSASSTFASSTTPQFPPLLHSIYIECADPFPQVDAFVAQTSATYGLQLARSAKPMKAALADYLAAEPQLRAVFVGTRRTDPHGAQLRFFDETDGDWPRFMRIHPVIDWHYTEIWTFLRELGIEYCALYDHGYTSLGGVNDTFPNPALKKADGEGFRPAYELTEDLEERLGRHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI53</accession>
    <name>A0ABR3ZI53_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alcohol dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ADH1</name>
        <name evidence="10" type="ORF">Cpir12675_001216</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.1" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000017">
        <property type="protein sequence ID" value="KAL1899992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd08297">
        <property type="entry name" value="CAD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940:SF3">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="9">
        <location>
            <begin position="20"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1899992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="354" mass="37448" checksum="B0B163974FED3571" modified="2025-10-08" version="1">MSSIPNIPTEQWAQVIEKTGTMPVYKKVPVRTPGPTEVLINIKYSGVCHTDLHAMNGDWPLDTKMPLIGGHEGAGVVVAVGSLVNDIKLGDHVGVKWLNDSCLNCTYCLNGDEPLCAKAALSGYTVDGSFQQYAVASAAHVARIPKECDLEAVSPILCAGITVYKGLKESGVKPGQHVAIVGAGGGLGSIALQFAKAMGLHAIAIDGGDEKGTMCMQLGASTYVDFTKSKDLVSEVKAATPDGEGPHAVILLAVTEKPFQQASEYVRGRGTVVCIGLPAGAFIRAAVFNTVIRMINIRGSYVGNRADSVEALEFFRRGLIKAPFKTVGLSQLPDVYELMEKGKIAGRYVVDTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI94</accession>
    <name>A0ABR3ZI94_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidase S8/S53 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_000896</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046503019" description="Peptidase S8/S53 domain-containing protein" evidence="7">
        <location>
            <begin position="28"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="8">
        <location>
            <begin position="230"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="487" mass="50133" checksum="8BA0772DC5FD3553" modified="2025-10-08" version="1">MASSHKNMSLRRLVGLAVMWSLPTAMAGPIFGGDGPGGRTRGGYRAGSSDYRDSSAFKGFPAGTGLPSIATSTESAVPSTVPTTVSTSSNTYSVLNAGAPNAVPDRYMVVYNNTFDSDTITSKQNMLIASIAKRNLRKRGLNGRQLSTKVKTYSVNHGRFSAMTLDSDNDMMVSIMAEPEVAYVEAVTNVKASTLTAQLNAPLGLVRLSNKDLETQSVSSTRYTFDSTSGSGITAYVVDTGIRVTHTEYRGRAIFGANFVDGSSDTDDNGHGSHVAGTIAGRTFGAAKNANLVAVKVLDSQGGGDTATVVEGMQWIVDDVEANNRSGKAIMNMSLGGTFSQAMNDAIEALRVAGVVPIVAAGNEGVDAKDSSPASAPSAITVGAIDATDDTIASFSNFGSVLDIFGPGVNVTSCGINSDTDTQTLSGTSMASPHIAGLAATIMATEGITSVDALTLRLKGLAKEGGAVVKNDILGTTTLIAYNGAQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIE5</accession>
    <name>A0ABR3ZIE5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_001196</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000017">
        <property type="protein sequence ID" value="KAL1899972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26113">
        <property type="entry name" value="GH16_XgeA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1899972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="371" mass="39470" checksum="EAFCC395D410A7EA" modified="2025-10-08" version="1">MAYVLAESYLAASFWDGFSVVQPSVTAAGSWAQYASSAKADNLNLTRVTDSGSVILQMDAVSGLAASNNSGLTTDRSKRNTVRVQSNRAYSDGLLVVDLEHMPAPICGGLPRLFAAGLEADLTVIQSTSLESSSQLHSTTSGSCILPDVEFLANRTATDCFTQCGFSTSPYYVGSSWNAANGGVYALLWTEGSATAGTSNSAAARVASSSVFVEPESTSGYLRVWAWERGDVPENVHSQQPEPALWGESLAVFGGDACRGTSYYRDLRLVFDMDLCNDAIEESWSKGCQQATSKKSCAAFASGNSEAFSQNYWEINTVNFYVPEEIKPVTTIGGAIPTFTTAPDATLTADKTILKATGKSTFVWIPSNTPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIH1</accession>
    <name>A0ABR3ZIH1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Eukaryotic translation initiation factor 5B</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Translation initiation factor IF-2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">FUN12</name>
        <name evidence="10" type="ORF">Cpir12675_001117</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03703">
        <property type="entry name" value="aeIF5B_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01887">
        <property type="entry name" value="IF2_eIF5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="entry name" value="Translation initiation factor IF- 2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029459">
        <property type="entry name" value="EFTU-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003078">
        <property type="entry name" value="PRK04004.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381:SF4">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14578">
        <property type="entry name" value="GTP_EFTU_D4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="Initiation factor IF2/eIF5b, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 10" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="419"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="260"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="316"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="39"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="128"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="146"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="179"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="266"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="290"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="320"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="372"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="393"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1900012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1013" mass="111074" checksum="F7887F72671D29AC" modified="2025-10-08" version="1">MAPKKKGGKKAAAAEDWEAELGEAAPVTTVDVDATEPTADANSADANSAEAGAEDEDENSGGGGLMAIMRRNKQKQTKKEAEVVPVQEPGRLLTKAEKDKLKKEREKQRKKEQASIVVSVAMLKKKNAPAAPATPAAAVKKEENEVAAPAAAPDTPEPTASSDSKKKIPAHLRLIQQQQEERRKREEEAAAAAAAEKARLEELERKEAEEAIRREEIKAAKKQREKERVEQLKREGKFLTKAQKEEKLRNERKLQQMLAAGIKVGAMDDDKEKKTKKEDQRKKGRGGPNKVDEQKALEEAAERARLEAEALAKIAVGKAAAEKAAAEKAEAEAAAAKAAEEDDVKDSWDASSDEETEGNAASANAKKNGDRDGDDSESSEDEETKNTRAALEAQRKQEAAERREKAHQAALNARSADNLRSPICCILGHVDTGKTKLLDKVRQTNVQEGEAGGITQQIGATYFPVEAIKQKTQVVNRDNSFEFKVPGLLIIDTPGHESFSNLRSRGSSLCNIAILVVDIMHGLEQQTLESMRMLRDRKTPFIVAINKIDRLYGWNKIDNNGFRDSLSQQNSSVQKEFQNRLDQTKLAFAEQGFNAELFYENRNMSKNVSLVPTSAHTGEGVPDLLKLLLQLTQDRMVNSLMYLSEVQATVLEVKAIEGSGMTIDVILSNGVLHEGDRIVLCGTEGAIVTNIRALLTPAPMRELRVRGSYVHNKEVKAAMGVKISAPGLEGAIAGSRLLVVGPDDEEDDLIDEVESDLATLFSRVETTGRGVSVQASTLGSLEALLDFLKDCKIPVATVGIGPVYKRDIMQTGVMLEKSPDHAVMLCFDVKVDKEAQQYAEENGIKIFQADIIYHLFDAFTAHQAEMLEKKKEESKMLAVFPCVLNTVAVFNKTTPIVIGVDVAEGQLKINTPLAAVRTGNNGQKEIVGIGRVTSIERDHKQIPVCKKGQPSVAVKIEMGNHQPTYGRHLEESDKLYSLISRASIDCLKDFYRAEVTNEEWLLIKKLKPLFDIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJG3</accession>
    <name>A0ABR3ZJG3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_001016</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000014">
        <property type="protein sequence ID" value="KAL1900332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42886:SF29">
        <property type="entry name" value="PUMMELIG, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42886">
        <property type="entry name" value="RE40534P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="153"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="496"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="496"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="516" mass="57131" checksum="1F58C922F26F4AA7" modified="2025-10-08" version="1">MLKTQAASTIVIRRPRLYFSAPHAANSRNTSSAYASSPSESDDPEHILMADLESDSNSKQPRMSLAQLFPQSFGESAKQWWACTNPKLAERRLLDMVPYLKEATSNNMTAPANSDDPFGFRVWRSQMVELSGKNRALNEYSVERVGEKVDENLVMLHGYGAGLGFFYRNYEPLTRAPGWKLYALDMLGMGNSTRPPFSVKAKTREAQITEAENWFIDSLEEWRTKRKLDNFTLCAHSLGGYLGVAYALKYPGRIKKLILASPVGVPADPHAISAEMPEPEESAMQNEFTRDQESIVHGKNATGPADAPKRRVPGWLSYLWDANVSPFSIVRFTGPLGPRIVSGWSSRRFNHLSQNDASLLHDYAFSIFRQSGSGEYAMPYLLAPGAFARSPLISRIDGVGRQVLPAPMGSSAAGVPLRETGIPIVMMYGDGDWMDAAGGFAAEQKLLKAREKALLTGTDYEKKNENGAAKVVIIQDAGHHLFIDNPEEFNKHMRAEMDETRAEGLRKKATASQSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJV4</accession>
    <name>A0ABR3ZJV4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 9">tRNA (guanine(26)-N(2))-dimethyltransferase</fullName>
            <ecNumber evidence="7 9">2.1.1.216</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">TRM1</name>
        <name evidence="11" type="ORF">Cpir12675_001025</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>guanosine(26) in tRNA + 2 S-adenosyl-L-methionine = N(2)-dimethylguanosine(26) in tRNA + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:43140"/>
            <dbReference type="Rhea" id="RHEA-COMP:10359"/>
            <dbReference type="Rhea" id="RHEA-COMP:10360"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74513"/>
            <dbReference type="EC" id="2.1.1.216"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.216" evidence="7 9"/>
    <dbReference type="EMBL" id="JAWDJO010000014">
        <property type="protein sequence ID" value="KAL1900341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047148">
        <property type="term" value="F:methylamine-glutamate N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.70">
        <property type="entry name" value="N2,N2-dimethylguanosine tRNA methyltransferase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002905">
        <property type="entry name" value="Trm1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042296">
        <property type="entry name" value="tRNA_met_Trm1_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00308">
        <property type="entry name" value="TRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10631">
        <property type="entry name" value="N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10631:SF3">
        <property type="entry name" value="TRNA (GUANINE(26)-N(2))-DIMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02005">
        <property type="entry name" value="TRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51626">
        <property type="entry name" value="SAM_MT_TRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 9 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="1 9" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="70"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="90"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00051897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1900341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="642" mass="71295" checksum="7A10B00EC0AA0865" modified="2025-10-08" version="1">MNSVSPDAPTYTYDDKVYTTIREGLADILVPVGAKIGDGGNKSNISVFYNPIQQFNRDLTVLAIRAYHEDTEERKESSAKPAKNKRKRKDTGAEVDSEKRSKVEGNADWESKKVESTSTETNAELSAQAAATQEVSNTTETHETETTTATIPIKSSEHEPRPRSTMSKFTILDALSASGLRALRYSHELPFVTSVTANDLSSSAIDYIKLNAEHNKLSDKIQVSRDDAIAHMYRRIADDLSKRDKHGNPSNNNRYNVIDLDPYGTASPFIDAAVQGVKDGGLLCVTCTDSAIWAGHSYCEKAFASYGGIPVKGFHTHEVGLRLILNTVATSAARYGLAIEPLLSLSIDYYTRIFIRVTKSQAAVKFNASKTMIVYNCDQGCGAWETQHIMRTRVMAAKSGKSHYYKHVMAQGPTSDILCRHCGTKMHLAGPMYGGMIQSPEFIQRVLNILPTLDGKVYGTAARIEGMLTTALSENLPEPDPEEALPQADKEAARIDAHPFYFIPSRLAGIFCCETPNEDLVRGALKHLGFRVTRSHCKPNSIKTDAPWTTIIWIFKEYIRQVAPVKMDNIKQNSPAWKLLNGGGELQQDNVVNDEEAALRKTLVFNEVLQKLGRDKEISTKKLVRYQVNPRENWGPMTRARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK65</accession>
    <name>A0ABR3ZK65_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_000901</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the Nibrin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10980">
        <property type="entry name" value="Nibrin, BRCT2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040227">
        <property type="entry name" value="Nibrin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032429">
        <property type="entry name" value="Nibrin_BRCT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043014">
        <property type="entry name" value="Nibrin_BRCT2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12162:SF0">
        <property type="entry name" value="NIBRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12162">
        <property type="entry name" value="NIBRIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16508">
        <property type="entry name" value="NIBRIN_BRCT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="8">
        <location>
            <begin position="21"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="398"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="442"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="746"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="562"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="414"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="456"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="749"/>
            <end position="789"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="840" mass="92571" checksum="A88AF4D770CC662F" modified="2025-10-08" version="1">MHRFANTLIGTQRWLRPGRLYLLGRTSNSANELAVSHKTVSRKHVAISVAAVDEGAAQNLTSRSAVIIEDLKSSKGTTLNGAALHGSKEVSGDNAEFKLGFNPEIFRLYWVPVILVYSSAAKSSQVDMLTNLRNQLEQLDIKFLADYHVQATHIVTRKRNTPKGLQALINAKYMVTNSYVDTIVAAAGSTPDTQGISLLEQDYSKHWPKPEDFVPPKGNEAIDRPPESFLPDAERQDVFKGYTFVFYDEAQHRNLMAPISSGKGKALLYNVDPQSTRADNLVQYVKTIAGETGIGEFDDGSVGPGVVVVRYVPTSGEDVEWYTRFITDVSLCLNHRAIEQSQFIEAILTKDATFLRRPLPTHSSATTNISTDPAALSTPILPPQYSTTLVLQPASAELSSQGTSGLGARGSTTRGRKPATRRFKGFDSDDDDVSVSFASQWQSGLQSGASTVPPEPDIHIPKGENQDSDDGLFVPEGPAVGVTQTISEVRSAPRRSTRPERKRPLQALVDDSLMDEIAPTAALAKRQRLENGEDPAIVENYARPESEPDQHSPISMPKQRKIKKELDVLEAARKVREQEEARLQRERDDMAQLPGDIDLLAIRQLHVVEEIPLRQRLPVPTVGSDDADSLVASGRWDPRWNGRRNFKRFRVRGDPVGRVPMRTIVSLTQVKTKDFGIGDDYWLEEHGSHRAEGHGNEEDGAKSDRHVERPGLTAAALQRATHYTIASESESDDDFLSVEDVQPIRRGQRGTAAAASSRAQSTTQLHGHGTLALASLSSTQSQPQGQPQGRTAQKRTRAQLSEAVAVEESTAKRTRATRKTITIPDSDSEEEGRFRFGRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK85</accession>
    <name>A0ABR3ZK85_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mitochondrial inner membrane protease ATP23</fullName>
            <ecNumber evidence="9">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ATP23</name>
        <name evidence="11" type="ORF">Cpir12675_000706</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Has a dual role in the assembly of mitochondrial ATPase. Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 at the intermembrane space side. Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of subunit 6 with the subunit 9 ring.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion inner membrane</location>
            <topology evidence="1 9">Peripheral membrane protein</topology>
            <orientation evidence="1 9">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the peptidase M76 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019165">
        <property type="entry name" value="Peptidase_M76_ATP23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21711">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21711:SF0">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE ATP23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09768">
        <property type="entry name" value="Peptidase_M76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4 9 11" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1900830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="252" mass="29241" checksum="4A7800F538CF7170" modified="2025-10-08" version="1">MSDSSSSLNPPSSTSVPKTLTNDPKRTGFDPTLAWYENLFRACTGRMTPEGIVHYRESRYIANEARDCARCEEYRDWMFKFSPIVRFMQQKIGMLHGELDERNIICRRCPTRMTDDGSVHRIGGGFSPDHGILICANEVRNKKHMEDTLAHEMVHAWDHLRWKMDAENNLRHAACTEIRASMLSGECRWTREFFTRGNWSLSAQFQNCVRDRAIQSVMARARCKDKAQASKVVNEVWDSCFSDTRPFDEVYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLA2</accession>
    <name>A0ABR3ZLA2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Bud emergence protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">BEM1</name>
        <name evidence="7" type="ORF">Cpir12675_000669</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000008">
        <property type="protein sequence ID" value="KAL1901179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05992">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06890">
        <property type="entry name" value="PX_Bem1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11878">
        <property type="entry name" value="SH3_Bem1p_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11879">
        <property type="entry name" value="SH3_Bem1p_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035550">
        <property type="entry name" value="Bem1/Scd2_PX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035548">
        <property type="entry name" value="Bem1/Scd2_SH3_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035549">
        <property type="entry name" value="Bem1/Scd2_SH3_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051228">
        <property type="entry name" value="NADPH_Oxidase/PX-Domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15706:SF2">
        <property type="entry name" value="SH3 AND PX DOMAIN-CONTAINING PROTEIN 2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15706">
        <property type="entry name" value="SH3 MULTIPLE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="32"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="148"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="PX" evidence="6">
        <location>
            <begin position="315"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="96"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="273"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="445"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="101"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="288"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="474"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="578" mass="63879" checksum="033DC6D31EEB3149" modified="2025-10-08" version="1">MHIFQALRRSMKSDKDKTQSTIAPKSAIAIVPPKKVIRALYDYNANSSQELSFSRGDFFHVIGRENDPDWYEACNPAVPDARGIVPVAFFQALGKTERDSVSNTPPDTGRTSMPKSEYDSGYGESAPSSAGLGHQRQPRSMGGGKGSGAMVYGIVMYDFKAERGDELEAKAGEAIIVIAQSDPEWFVAKPIGRLGGPGLIPVSFIEIRDMASNTPVPNPQESIRKAGIPRVEEWKKMAADYKNSSISLGKFDTGSAPNSNQPTQLEQGIERLSLQQQQQQKQQERLSGHTTMSTATPPSQHDQAPVTSYGAKVTSQLIAPIEARIPRYCFADEKYWFVIEAVLEDGRRWELSRYYEDFYDFQIALLTEFPAEAGNVTNKKRTLPYMPGPVNYVTDAITEGRLHNLDAYVKNLLQQPPYISKCTLVKQFFAPREGDYEVDPNAEEDYQLSGGQEGSLEGQNGNGYGSTPRHISTGGPQAQPSHSSLSNGSSAMHGGAVSAMKIKVCFDNDLIALIVPTDIQFETLHSKIRERFKIAPHENMKMSYKDETTGDTPSLLNNSDLDTALERNDKLLIYVERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLI5</accession>
    <name>A0ABR3ZLI5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000439</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="222"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="551" mass="61329" checksum="BB1898834E7DDE25" modified="2025-10-08" version="1">MAEDEEMTEGGPSSAVVDRAPATLMWDTQSCVPLTNVLRKEDDLIVLLTPVVVHPDGNPNLTTDPFESFGRALAERHPMIRHVPYTKRGGITSTHVAFIKRAAVVIFVVSGLPRHEDEPSQLEFADVARVVSEHRTFVLLACYDFEQQDVAHLGIHTLVHCDGYARPELEAAAGVFFGRRWDSAPSSPAVTLPITNVAPHHHHGLPIPMPYPNASGPSHWKPEVWDLNHGEIAPIHALWEMCMPSQFCLTPKRLNSVLRRLGYSTHYIVRTPSGQMIGFCATFVNYLAPDSPDYMGSIAMLLVHPDFRRQGIGTAMHDYAYDQLKNTPKVVRIQLGSTFPRILYGVPSNYPNLGWFRRLGWEIDFDAPGKGRVVTDWVLNFEDLPGNEFSSAGLTFKRCEPAEFSKVVDLVYYASKRKENLGWPDTYGKLSPETGRNPNNIIVGMEGSTIVTTALIYVPNDGVPPDEDLPWAGTIGPDVGGVTCICINDTDPTLVVRPDAIMIRLLDTCVRILTEKGMRKLFIDGTRGGEQGFVSLGFRKWASYREVWKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLM3</accession>
    <name>A0ABR3ZLM3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000013">
        <property type="protein sequence ID" value="KAL1900409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="478"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="522"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="121"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="522"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="544"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="565"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="582"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="602" mass="62913" checksum="376BA68EACD4D103" modified="2025-10-08" version="1">MQQPDSSQRNNARILNWNHDVAKSTGSVVSSASNMKNPAKHHSTTVSRQPSKSKAKTQPKVPVEVDEGPTLLDSAGAAIFGLVGLAAGAALTYSMVKDNKTKTTETAIAHAVSTVTTTVNPAKPSAPKKAAQTAANGKNYGPSASRTGQIQSGNSYYVKAPSTVYAPSEVSMHKPLMITAPPTKGGSVAGSRTSRANSRARRAPSQADPDDWKTVAGAGRAPSQARQADPDDWRTVVGAGRAPSQARQTDTDDWKTVAGAGLGAGRAPSQARQPDTDDWRTVAGAGRAPSQARQTDTDDWRTVAGAGRPSSQARQSGPNDWETVAGAGRSAKNPSASSFNDFETVADASQKYGNNFGMSGAARSAKNPGVSAFDDFETVADASQKYGNNFGMSGAARSAKNPGVSAFDDFETVADASQRYGNNAGMSGATNWKNSAAVSTSRRGGGGYGDDWETVVEQDRPLMTGILIPNDFETVVDGSHPRGFPSESVAGSNAMKPRGIHINAGPDDWRTLVDESDRCSQASRQYSARDAQTTRVPLRGSKNAASSQAPSQAPRGSVKSKKGAKSTVSMSSKVTSRPPPSDFNSWDTETVLPNDSISCVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLZ3</accession>
    <name>A0ABR3ZLZ3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Mitochondrial aspartate-glutamate transporter agc1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">AGC1</name>
        <name evidence="14" type="ORF">Cpir12675_000240</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="11">Homodimer (via N-terminus).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051028">
        <property type="entry name" value="Mito_Solute_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45678:SF9">
        <property type="entry name" value="CALCIUM-BINDING MITOCHONDRIAL CARRIER PROTEIN ARALAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45678">
        <property type="entry name" value="MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="EF-hand" evidence="13">
        <location>
            <begin position="85"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="13">
        <location>
            <begin position="157"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="330"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="429"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="527"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1901733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="681" mass="75285" checksum="EF8B37A7CDD26880" modified="2025-10-08" version="1">MTALPPSSSSSQAVLARFEAAAIKDEAGQLFIGPEQFVNAIAPAGEDYHRIHRDQYALLFHAADRQKTGKLSLADWELFESLLAKPDAEYQIAFRLFDVGRSGHVSYEDFKNVLEANRSPDSLPLSLDSQWMRLHLGTSKQRHDMDYPQFAQLLRGMQGERIRQAFVHFDPSGTGFITPADFERIVRETSRHKLSDYTLTRLSDLCENMNVGAAGKISYATVRAFRNVIDSIDLIEKVVVQACTKSSDGKISREDFFSTAALHARFQAFTPAEVDVLFRFASADSKADRLTPADFRRVVDSSWRKPVSLASEAAEKAKKDSQLSWGQQVLVSSYNFLLGSMAGAFGAFMVYPIDLVKTRMQNQRTAGPAGNALYKNSIDCFQKVIRNEGFLGLYSGVLPQLVGVAPEKAIKLTVNDLARGYFSRKDGSIHVGAEIISGSTAGACQVVFTNPLEIVKIRLQVQGEASKTNAAVPKRSAMWIIRNLGFLGLYKGALACLLRDVPFSAIYFPAYNHLKRDFFNESPSNPLGVLQLLTAGAIAGIPAAYLTTPCDVIKTRLQVEARKGDIQYTGLRDAAKKIWQQEGFRAFFKGGPARIFRSSPQFGFTLAAYEVLHKTLPLPSHLASRKEISYLGDEMALYAPFVRSRNALKAVLDLDENFGRVAAPDAKAWKVLDKAVEAVYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM30</accession>
    <name>A0ABR3ZM30_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin-conjugating enzyme E2 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">E2 ubiquitin-conjugating enzyme 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Ubiquitin carrier protein UBC2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Ubiquitin-protein ligase UBC2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_000625</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000008">
        <property type="protein sequence ID" value="KAL1901136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23795">
        <property type="entry name" value="UBCc_UBE2G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="9">
        <location>
            <begin position="8"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="7">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00039884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00041569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1901136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="177" mass="20206" checksum="A205F8E63237D07E" modified="2025-10-08" version="1">MSSSEAAAAGALLRRQLKEMQRQTELPGISVGLVNDNNIFVWEVMLMINDDCKYYGGGNFRAHLTFPPSYPLMPPQLTFQTPIPFHPNIYEDGRLCISILHPPEEDQYGYEAASERWSPVQTPETILLSVVSLFHSPNDESPANVEAARLLREERDGKHREYRKRCRKCVRESLGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMT4</accession>
    <name>A0ABR3ZMT4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000288</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="298" mass="32103" checksum="B3CADC7C2D28AE47" modified="2025-10-08" version="1">MPSAAIMSFAEGDSVRLFASMTTRTVTCGSAGCGTLRVWDFDDGPTPVAGELGVLVTCLDDLALPPEAQNGMLYRNVQLATSMFSALPAPSNSANASTESLSPESSESAPHIPRRISSGAIAGIAVGVIASLGLFITLLFLVRRIFHRRHSSRSHPHSTIPGPQSSSPMPNAVRSGEKTPADYLSLTGAASELDSPKVSWALWRRVKATDVPQELPPNSRQAELPASVAMPLELDDTSHSLTMSSAVPEVLERRAREREWTRREEQAGETANNIPVHPYDFYSPWDRSLGLQANRDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN85</accession>
    <name>A0ABR3ZN85_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein rds1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00657">
        <property type="entry name" value="Ferritin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039254">
        <property type="entry name" value="Rds1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38705">
        <property type="entry name" value="PROTEIN RDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38705:SF1">
        <property type="entry name" value="PROTEIN RDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13668">
        <property type="entry name" value="Ferritin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046697417" description="Protein rds1" evidence="1">
        <location>
            <begin position="17"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="317" mass="32587" checksum="6BB3080CCF9EEF83" modified="2025-10-08" version="1">MKPAFVALAVVSVASALPALPKLTPRELHMLELGKRQNKEAEAAGLTDNDILQFALTLEWLEATFYQEGFKKFPPADFTALGLNDKQLTDLLALPTSEFSHASFLQGSLAQGGITPVQPCTYNFGFTDAKSMVVVAAVLENVGVSAYLGAASLVSSSNILTAAGSILTTEARHQTFIRTAAQLVAVPQAFDAPLTPRMVFTLAAPFITSCPEGSNLAITPFSALSVTDPAAGTPAPAGTKLTLKPADATGATHCAFTSGGVTPGGSVFAPFDAATNSCAVPQGVAGVTYVSLVNSAPLTGVVNETSIVAGPTFILVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPC1</accession>
    <name>A0ABR3ZPC1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome c oxidase assembly protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_000199</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PET117 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031568">
        <property type="entry name" value="Pet117"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28163">
        <property type="entry name" value="PROTEIN PET117 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28163:SF1">
        <property type="entry name" value="PROTEIN PET117 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15786">
        <property type="entry name" value="PET117"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046893498" description="Cytochrome c oxidase assembly protein" evidence="5">
        <location>
            <begin position="23"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="83" mass="9521" checksum="4F6F193C4E42EABD" modified="2025-10-08" version="1">MSRASRFTIGLSSVFATATVLAVHFQQQAEKTAMHQGVLRDMEQQRIKHERQLDFDAQRTLEQEYMKDQTVKEADLTGVPKDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ49</accession>
    <name>A0ABR3ZQ49_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">H(+)-transporting V0 sector ATPase subunit e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">VMA9</name>
        <name evidence="10" type="ORF">Cpir12675_000329</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the V-ATPase e1/e2 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008389">
        <property type="entry name" value="ATPase_V0-cplx_e1/e2_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12263:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12263">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05493">
        <property type="entry name" value="ATP_synt_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1901639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="76" mass="8304" checksum="1C34CB435B765F92" modified="2025-10-08" version="1">MATGSCIFIGLFICAALAVAAYLFAPKGPNQILWRSSLILAIVSCYLMWAITFLAQLNPLVAPNRIDLRVPSQHDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YBF6</accession>
    <name>A0ABR3YBF6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">5'-Nucleotidase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_007001</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000523">
        <property type="protein sequence ID" value="KAL1885330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="entry name" value="5'-Nucleotidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575:SF24">
        <property type="entry name" value="5'-NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="5'-NUCLEOTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="5'-Nucleotidase C-terminal" evidence="4">
        <location>
            <begin position="133"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="329"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="551"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="331"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="551"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="591"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="627"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1885330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="638" mass="68430" checksum="FBFE51F7B3714A97" modified="2025-10-08" version="1" fragment="single">ANTDIKRIVALTHIGIDHDIELAKATRGLSLIMGGHTHTLLGDMPGAEDKYPVIAEDADGNEVFVVTAHRWGTYVGEIEVAFDEDGHALSYEGAPIPITDKTPFDAELQADIDEWRLGFDYYASKVVGSAVIDLDQTMCQLQECLLGNVVADAMIDYVMRNPKSKISKAEKKRYFALVNSGGMRATIETGKVTLGEVLTVLPFKNNVVDVEFDGSTLWEIFEGAVAKQNIVNGLPITSFFQVSQGVEIVYNPAMPTGSRLISVKINGKQIMFGETYHMVTIDFMLEGGDNMLLLDNANQKATYEELDVVLLDYLDHRSPIKAQIDGRIVKSDVSSSSEHEAVSSSDSDSDSDSDNEAVSYADVHVASTGALPVHAAVSTGSYPNTTTGYSNPTATLVPLGSAGSTAVSSAPRPTYLETEVFGLNYCNDKDDEDDYHSCSSDMEGDYGWESDDESIEEDPIYHATIATSSLATSTLVTAPAATGSGVPIDYQATSSGYNQTTSIGALSTGISVVLTTGPTKSISMTVRPTHSEAEINGLDYYMDWSDSDLETDYDTDSSDKDEDYEAGVSTGAGNKKTADKKPTGKTGGESSDSESESDYDSDDEGEDQKHGKHPKAKSTKVPMVTGTIPSFNINPTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YCJ1</accession>
    <name>A0ABR3YCJ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DnaJ (Hsp40), subfamily C, member 17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">DNAJC17</name>
        <name evidence="8" type="ORF">Cpir12675_006912</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000421">
        <property type="protein sequence ID" value="KAL1886029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052094">
        <property type="entry name" value="Pre-mRNA-splicing_ERAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44313">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44313:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="7">
        <location>
            <begin position="6"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="72"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="440"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="87"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="137"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="263"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="296"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="455"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1886029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="472" mass="54700" checksum="0F33F05AB42BC825" modified="2025-10-08" version="1">MSTQQDLYGILGVPKTAEFAEIRSAYKKKALSCHPDKEPNEDLKVIKQEQFQRLQTAYETLRDASKRAKFDELIARHPSGAPRNPNIYKSRTSVPPQTTDPYAYPRPPRTRQHSPFSPGRSAPEETFEFSRVYNPERPVHRQSSHEKTPHKSDKWRDNYDDLRPGEARRVKEEKLRRKADDAIKRDLEEKDKKEDVERSDEKLLRKTKERERMAKEASKRQFDTRKSFEGGKVRSVDRKAKKEQRYHDDIGSDLEGDFIDSSPKAEKKKPNSKEKRSHSAPRASVVSPDSIETDWSEQLKQAQSYITERKKKTEKSANVETPAARRTRRMSGDSPRKSSHRKSQHEEAFIKPAMSRGATFPTTASYTSPKLHRSATMENDCRVKSAYRNSPRIVEDDFFDSNYMSFPRGSREPDISIHSTSAMYTGYEYSAMPMPHSWPDPHGPHVATTRRYTSDDVQYSNQYPTDYTDHYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YCZ8</accession>
    <name>A0ABR3YCZ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thyroglobulin type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006997</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000517">
        <property type="protein sequence ID" value="KAL1885334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047286638" description="Thyroglobulin type-1 domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1885334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="64" mass="6813" checksum="3782FC4B7F7A32E2" modified="2025-10-08" version="1" fragment="single">MQYWAVTLLLAFTASAMASRVGGVGPAPDTDDGPGLEYTDCSFSGEFCWCKNNSGQSIIVDSSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI94</accession>
    <name>A0ABR3YI94_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000282">
        <property type="protein sequence ID" value="KAL1888051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="314" mass="36356" checksum="39E5F4BF818F7C86" modified="2025-10-08" version="1">MRFSSLLSCLGISLPGLQDSRSSSTQDLQDTEITQPEFTPTTGFEHTEEFELDYTDEPYDFKTTDITSQDYLPTRGYYGSFFSHGETRVYSDHYDEFGSKTMLQIFFDEERKVASIRDNNLRYEEDHKYKLPLYKIFEALCYRQSLDYFSLDWIVMDIFDSDTVSFIEQYRESNNLGIEADIRLTDEDIYWSLFCNTDYYHQASHMIPARIDKMIIRRQERWIEGTNYPPAVAHLIMFSFKSSESKGQDPPATDPTEIRALEIVGAAIKAVDEREATNLKNELGIRPEAGADTLEDFAEAAPEKSDTELAWETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ53</accession>
    <name>A0ABR3YJ53_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pre-mRNA-splicing factor 38B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006374</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000290">
        <property type="protein sequence ID" value="KAL1887887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40132">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR 38B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40132:SF1">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR 38B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="123"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="253"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="417" mass="47096" checksum="A398DB2731C4E0DA" modified="2025-10-08" version="1">MSKAPSNPNHLLLSDDYIAGLLVQDAADYALRYSAHGLDALKTEQSSSSQPKPNTRFLRNIIKATDSHNAALLAKEAAESHARLHRLNSPSDDSRHRSSPKSRDVCRRQFSEINAILGNQGTSRSAKNMESSRSSRSDSKSIDNKQKDSESASDYNKRSRSRDKRRDHDRGLKDIQESQKRRRYRSLSPERDQGRGRQCGSGDKSRRDHRTRKDKDHRPPRQSSGHSRSHRHRGDTETPTSRSSRRRCRSSSRSKSPQSSSRSQHTRRQRSPMSRPSNSSATYSKPKEESANGSSEDDSEDDYGPLPQSSAKPQSRPRGRGAISEASGIDSHFAADYNPRTDTPSDVRIGAQTLAKTTAATTTPETDMWAQATNLYRERQKMRVLQETNETEMIASVKWKKHGEKREWDVGKDKEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJX2</accession>
    <name>A0ABR3YJX2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Palmitoyltransferase</fullName>
            <ecNumber evidence="11">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ERF2</name>
        <name evidence="14" type="ORF">Cpir12675_006133</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="11"/>
    <dbReference type="EMBL" id="JAWDJO010000257">
        <property type="protein sequence ID" value="KAL1888512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883:SF43">
        <property type="entry name" value="PALMITOYLTRANSFERASE APP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11 14" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="395"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="539"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="584"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="13">
        <location>
            <begin position="495"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="166"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="212"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="93"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="130"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="224"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="244"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="279"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="327"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="340"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="351"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1888512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="722" mass="78840" checksum="6EDD3E1AE2D02FBE" modified="2025-10-08" version="1">MAANANDLASASTGTEHTQHATNLYSHAPPQPTAGPPSIISSRMTDIASEEGDRDHEAASQTASHIRSVGDAPGNKRRSLLASEVASRPETARTGTSARAWSGNQPLRVPHFSTSGAGNAHRGSIGGGSTTTATSIMSRSGIGSRGQNSRNHVPSVANQAFFHPMSSQKLQAQRAGTAGRRPSETPSTHSALSAIAPTNAATNFSAGLARMGKPFGEYDRDNHAQSPPSRGTEWTEQETLDRLTANTSPTGHRPQESLTESMKPLQRRRDRETELIVDTSRQYSTSKNTQAVRTHNRSPTKTSRSFRSSLFNPTGASQARNNGAEKLASAASSPRLASTESHDVEDIKTSADATGSNGKSRLNNGGSGSKVYQYFDGNTVFCLNGRLQNTHAKPINIATGVLVALPIGLFFGFSAKWIWKHISPAIPLTFAYIAYLCLSSFLRASTSDPGILPRNLHSFPEDTPENPTASLLPTNDWVLVKSAEASTAAMEVPVKHCRTCDIWRPPRAHHCRLCDNCIEGHDHHCVWLNNCVGRRNYRFFFTFVSSAAFLSLYMVSVCLAQLLVYKNRQKVDFSDAISEFPVTFAMVIYGILAGLYPLALTGYHIFLMARGETTREYINSHKFTKSERYRAFSQGSIWRNWIAVLCRPRPASFYQFKKQYVQGDQRLGELRRDQRKRGSLELHNVRPVAMAAGAASGAGPVQPVFQGPTVLRNEARVELGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK11</accession>
    <name>A0ABR3YK11_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">RuvB-like helicase</fullName>
            <ecNumber evidence="13">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">RVB1</name>
        <name evidence="16" type="ORF">Cpir12675_006264</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the RuvB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="13"/>
    <dbReference type="EMBL" id="JAWDJO010000273">
        <property type="protein sequence ID" value="KAL1888202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.360">
        <property type="entry name" value="RuvB-like helicase, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027238">
        <property type="entry name" value="RuvB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041048">
        <property type="entry name" value="RuvB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042487">
        <property type="entry name" value="RuvBL1/2_DNA/RNA_bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010339">
        <property type="entry name" value="TIP49_P-loop"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11093">
        <property type="entry name" value="RUVB-RELATED REPTIN AND PONTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06068">
        <property type="entry name" value="TIP49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17856">
        <property type="entry name" value="TIP49_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0010">Activator</keyword>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 13" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4 13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 13 16" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0804">Transcription</keyword>
    <keyword evidence="13" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="15">
        <location>
            <begin position="63"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1888202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="458" mass="49761" checksum="9AB3269DC7126C3E" modified="2025-10-08" version="1">MVQISEVKGNKRDNRTATHTHIKGLGLKADGTAEKLQSGFVGQETAREACGIVVDLIKSHKMAGRGVLLAGGPGTGKTALALAISQELGTKIPFCPIVGSEIYSTEVKKTEVLMENFRRAIGLKVRETKEVYEGEVTELTPEEAENPLGGYGKTISTLLIGLKSAKGQKKLRLDPSIYEAIQKERVTVGDVIYIEANTGACKRVGRSDAYATEFDLEAEEYVPIPKGEVHKKKEIVQDVTLHDLDVANARPQGGQDIMSMMGQLMKPKMTEITDKLRAEINKVVSKYIDQGVAELVPGVLFIDEAHMLDIECFTYLNRALESPIAPIVVLASNRGVAKIRGADDISAAHGIPPDFLTRLLIVPTTPYNSEEIKQIVKIRLLTEGVSVTDGAVDKIAEHGVRISLRYCLQLLTPASIIAKANGRTQIDIQDVSECEDLFLDARRSAKILSSETAAGYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKB7</accession>
    <name>A0ABR3YKB7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">YVH1</name>
        <name evidence="7" type="ORF">Cpir12675_006071</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000249">
        <property type="protein sequence ID" value="KAL1888706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45848:SF4">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45848">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 12 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="6">
        <location>
            <begin position="284"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="21"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="200"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="443"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="67"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="211"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="241"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="264"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="280"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="593" mass="65714" checksum="42A481653616F68B" modified="2025-10-08" version="1">MDDDPLAKSLKTQRLSFINRLSELQREAQSDPVARPRAPGVPTNGDLPEDPEEDDPSARSGPDFRTRTTTTTASTTAFPPSPSSSATPHSPSSLSRDFGPELDGEDEFRNKPRERLDRALSFMALNRIPGDAEIYVGGVFALKRPQALKDHGITHILTVLGNMMDGVVPTNVYKHHVIEIDDMDDEDILIHLPKAIRFIDDALNPPPPPTATTAKPLQTQETKPTSLPSSPSSPRAPTSKPEVEESITDRADREAAEMVLGSQPPRTSALAATPAPPTAPVAEPESSPEVKATSKPSTPAPRRNSVYVHCAMGKSRSVTVVCAYLMWKYPEYFGLSAVVALDPARKILRRRRGHDAMLDAIDWVRRGREIADPNPGFREQLAMWWEMACPEDVESHPIYRKWAFRREVDASVACGMAPTILRFEDEEDAAALARLELAEDEDDLDLDADGNPRVTGAAGTSAKPPQQPSLRCKMCRRTLVTTPFIVSTDHQNPFAPEGANPDVLCQHYFIEPLSWMRETLQAGELEGRLLCPNKRCTSAVGRYSWKGFRCSCSEWVTPAFSLQKSRVDEVKELPIGQRMRELGIRRPPRRQNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKR6</accession>
    <name>A0ABR3YKR6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_005984</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000239">
        <property type="protein sequence ID" value="KAL1888921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF146">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1888921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="505" mass="56161" checksum="B812042D4EDAFB90" modified="2025-10-08" version="1">MSQYDALQSWATANGAYLNPKVAIAVSPTTGASFVASEEIPRSEPIVSCPMRLSLSYLNVLEGAPADFINPWTTSPPDSVANAGNRPAIVKNIPLPADFLASTPPNVVSRFLLMQQYLAGSQSYWNAYINALPQPGELQLPVFWDSDDTELLDGTNLGASVVEIRTRLADEYAAARKLLTGWTEGGWREFSRELYYWAYGIITSRSFTPLLVIPKGVQAALAAPLGGRRMDEFSLLLPLYDIANHDMTVPVTWTPLDAGENDGGLSRVTLTVDRVHAKGTHVFNNYGMRTNSQLLLSYGFMIPESETLHNDYVHLKKRNQKADVTDDYILSLHPATDQRSVLLEHRQMVEAGKLEAFSNSGKHEVLSSFQRVQDKIVYDLVLMHASLDKLREKLGVQADLQTNSIKQEVLARLLTNQVPDDVRPWLLQTMAVIGGQAMVALEKLDETEVEVDEDQMPYLTQNQRLGLGYRKACRRVLENVLEAIDTRPVEDGGEEEEQEEGGKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKX0</accession>
    <name>A0ABR3YKX0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mitochondrial thiamine pyrophosphate carrier 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Cpir12675_005955</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000235">
        <property type="protein sequence ID" value="KAL1888983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="EF-hand" evidence="14">
        <location>
            <begin position="52"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="14">
        <location>
            <begin position="88"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="14">
        <location>
            <begin position="119"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="356"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="476"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="583"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="221"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="221"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1888983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="676" mass="74212" checksum="39FDF15424A2BB48" modified="2025-10-08" version="1">MTAPGISQNGHEYQLDSRTKQLWSRLDLQGKGELDLNGLQLGLHNLGHPMKNADHMLRQMFQEADTNRDGKIQFHEFQSFVRQAEAQLWNLFQSIDTDKDGQVDKSQMQRAFERAGIAVPKDRLSNFFNHVDNDNDGYISYLEWRDYLIFMPPSRDSTSLHAVLSFWSSIVTLNAEGDSLVSDESLHHTSKNDSLLHILFGSIVRIAAPGDAERALKYQTTAQNASGTQRTADPSPTTLPKPTNSASTTHPTQITQAPAEASIQEPTTAYVVTGRKRNTLRVPNGTEPVMNPTITQALVSSPEIGMASPGTNMALAEEFIEPLEHDFLCPQEDQSTDYAATTTSTAKPQLKLSDFVPDPGYFLAGAIAGGVSRTATAPLDRLKVFLLVNTNVTHGADSVMGALKMGNSFNAISNSMAPIRSAVLEIWSQNGIRSFFAGNGLNVIKIMPETAIKFGTYEAVKRAMANFEGHNDTKQISSWSKFASGGLAGIVAQFCVYPLDTLKFRLQCETVKGGPKGNELIIATAKRMYQTGGVQSAYRGVTMGLIGMFPYSAIDMSVFELLKKTYKSYVSRRQGIPEDEIEPGNLVTGMIGASSGAFGATVVYPLNVLRTRLQTQGTHMHRATYTGIWDVAHQTLKNEGVRGLYKGLTPNLLKVAPALSITWVVYENSKRFLRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLF4</accession>
    <name>A0ABR3YLF4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Roadblock/LAMTOR2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000248">
        <property type="protein sequence ID" value="KAL1888717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="245"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="380" mass="37304" checksum="8818F1F830E3157C" modified="2025-10-08" version="1">MAQSAPSPPPLLLTKRITSFLARSLSNHIHTVLLCSPAGKLLAHVSSPFRPVAELRTQATVAASLISLYASSGSKLAPVLSRDSDVDNLDDAPSDSSSTNENGGYSYVTSPSHSRPHGYGYSNNGPRPALGSVPPLVLPAVASADTDMPHDLGERSSGPRPKTITVQLAGGAVIVRELACGLLFVCVGTAAPSPCVEDATHAALSSLSLHGQAAGSAGPPVATTLAQQPASAGPRNPPGSGSGAGSTAHSHTASNNHNGAGQNHVASGGSSSGGAPNGASTTPTGPVLGSTAATGPPSGSATCSTGSGLLLAGGLGGMHLTDSPDEADSVLSAGGMTTASVASTASAVAVAGMKRVAEEAARRLDAKLAALCVPDEGVFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLP0</accession>
    <name>A0ABR3YLP0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SEC63 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006047</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000245">
        <property type="protein sequence ID" value="KAL1888763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.10">
        <property type="entry name" value="Sec63 N-terminal domain-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052247">
        <property type="entry name" value="Meiotic_Crossover_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004179">
        <property type="entry name" value="Sec63-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47835:SF3">
        <property type="entry name" value="HELICASE FOR MEIOSIS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47835">
        <property type="entry name" value="HFM1, ATP DEPENDENT DNA HELICASE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14520">
        <property type="entry name" value="HHH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00973">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158702">
        <property type="entry name" value="Sec63 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEC63" evidence="2">
        <location>
            <begin position="27"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Helix-hairpin-helix DNA-binding motif class 1" evidence="1">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="360" mass="39090" checksum="FE3A4FC7237E5BF4" modified="2025-10-08" version="1">MPTPLRLPSTPASSAPGPKKTIAVSLPPGLIHLPGRHNLSTSTVHNLSHLSRAASARAVFEACCKSNDTTHHRIDPSHLSFFAAVNASPAIPWHLPVGIKPSLPWHKAFLLVQISLCPAGATPSNITAGARKSLAIEKRTVFNHLAIVIRCAADLFGCRADAVSLAATLWLLRCLMSGVWDEPAKELLQVTGVGPKKAEALVAAGVRTTRHFAELDSSHIERLLKRQPPFGEALRRTLAQFPRLTLALRQCGWQQPIRRGRQAAIVEAILGMENEGTPRWRGRVLRLVLWGSTTDDEKNLAFFWRGNIVDITKSRNKEQDNSRGLIVRFAVEAAVGQSLTCSLACEEVAGTLVKCAVALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLV4</accession>
    <name>A0ABR3YLV4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Sodium- and chloride-dependent GABA transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">GAT1</name>
        <name evidence="12" type="ORF">Cpir12675_005849</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000223">
        <property type="protein sequence ID" value="KAL1889283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013860">
        <property type="entry name" value="AreA_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039355">
        <property type="entry name" value="Transcription_factor_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071:SF281">
        <property type="entry name" value="BOX A-BINDING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071">
        <property type="entry name" value="TRANSCRIPTION FACTOR GATA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08550">
        <property type="entry name" value="GATA_AreA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00619">
        <property type="entry name" value="GATAZNFINGER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="11">
        <location>
            <begin position="852"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="45"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="105"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="290"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="412"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="692"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="906"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="948"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1122"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="243"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="472"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="693"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="760"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="795"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="842"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="908"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="948"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="967"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1039"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1070"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1122"/>
            <end position="1138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1889283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1154" mass="120487" checksum="8FD69B6ACC56A932" modified="2025-10-08" version="1">MAESMNLFGATSRSAAQTPTSLSLSAFDLEFDYADDTQLHASAQSHHMLTASSSESVSVSAHTPTKHVHDSQSYNHRQNHKHFDVAAATLHLFDAGMPPMRSLQAVAPSSLSPLSPHPNRTLSATADDDNSSSKNAQSHKSLPPPSSPPPSLDELAMCVWKFFSQAKQSLPQQQRIENMSWRMMHAGLRRLSMQAHASKPSCSSMSSGTAVGSSTLSALSVASTSLSSNHSLSFHGPSGIAQQLQKTSENCHSMQSGPSSERAAVAVDSMNLDDFICDSIAATPIPSSHVITQSSLSPNSNKGGDSGLDNQGTHALASAIPIKARKPAFVSASASASGAGIGSVSDDFADAAAPVAKSGSMIMSGGSQAHGSLQTQHHQSAQNFVPQSLPYPLNHHGRLKDEFNYVTIHHRKTSVDDRRTRKRPANFSPQVSATTSLNSSNNLEPESELHEYSLDNTSTASAPGTGTGTGTGSAATPTVMGTQQQQQQQQHQQHHHHSHHSSATSVPFPLDSYSMGNDPNIISVGPYQQAFPFSPSTSPLMQHGPFSSAFGGINTNSLNNRTAYFAPGISNFQAPNNPTSHSIGETDQPFYDNIENRHHGSIRPASHGIPTSLSPQYIFDPTNNPMFSATEPTTTFDSPFNVTEPSHVFPGQSGRSPSTISMPTDSMFSSFGADSDEEENTAFPDRLGIASEFSPSASLEETGTISTSSAMNWDPTLSGQFQTHAARFPGGPPRKNTMSSEADKPEWDSSSAPRSQLIHGTTGTTITTTTTNSSNRRSKALRAAPGTNSSQSRINPFASSNSNSPPADAPTSLPGGFMSAQPSRQSSPPPPQKSASTTNLQTNSSSAATADNSSPTTCTNCFTQTTPLWRRNPEGQPLCNACGLFLKLHGVVRPLSLKTDVIKKRNRGTGAATPSSTSTRAGKKSGLSSRKNSTLALSSTPAAAAVVAAATASTPPSNMRPGSATNDGDSPGASAAGGKTAGSTPNGFPINVNNKVVIPPASQPAARVGTAQNRTSTTSSKRQRRHSKSAGSDLVSAVSMPPLSSTSLSSTTTATAMNGSNSTQHHHSQSMDIDSPGSSDSADLMRSFSASHGLGPSIGSPGSLGLTSAFGLANANRSIVSPTVSGTSAAGQQQNMLGSGSAGPQEWEWLTMSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM32</accession>
    <name>A0ABR3YM32_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ENTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_006002</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the epsin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000240">
        <property type="protein sequence ID" value="KAL1888913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16991">
        <property type="entry name" value="ENTH_Ent1_Ent2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013809">
        <property type="entry name" value="ENTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12276:SF110">
        <property type="entry name" value="EPSIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12276">
        <property type="entry name" value="EPSIN/ENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01417">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00273">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00726">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50942">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENTH" evidence="8">
        <location>
            <begin position="10"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="149"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="333"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="500"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="188"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="355"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="374"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="516"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1888913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="539" mass="59726" checksum="D0A923AF103064B2" modified="2025-10-08" version="1">MSKVMRSVKNVTKGYSSTQVKVREATSNDAWGPSGTQMSEIAQLTFNGGSDFVDIMEMLDKRLNDKGKNWRHVLKALKVLDYCLHEGSIKVVSWAQANIYIIKTLREFQYMDEDGRDVVRVAAKELTSLLIDEERLTAERNDRRSWKSRVTGLDEYGPPTEPSRSRPQRYQGNDENDVEYRLAIEASKAQEEEDRQKREHQPASFDDDDDLAKAIQLSKEEEDRRRKELEQASAANNASLFDDDLIQITSTQKVQPTGFNMGYQQGQPVDFFANPVDQNQNQPQPTGYMTYAYTGVQNQPTGFFQNGYGMQQPNMSDMYQQQQNMAVLRQTQPTGFNNPYALQVPSPQPEPPMPTGSNNPWATSNAGLMKPAPTGSNNPFSAPSGNTSNSPFNRPRTAQASGLGSLPEQNPIANFQSQPQPSQTQRDLSDHEQKLNALLAGGDGMDTFGNTGNLRIPAQHTAPGTFVNSAGSGINKLNADATGNNPFLRTQFTGMPSVQYPQSQAPSATGPVGYGTAQNNNPFAMRQQQSSTPQDLIQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM97</accession>
    <name>A0ABR3YM97_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">O-methylsterigmatocystin oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_005898</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000228">
        <property type="protein sequence ID" value="KAL1889175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF5">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1889175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="493" mass="55234" checksum="A102C5FC5771A871" modified="2025-10-08" version="1">MVTIVVISVLRHFLPCRRTCHLPLPPGPPGEPVIGHLRVIPTDNPEYAYIEWGRELKSDILSFHVLGQPIIVLNSVTAAVDLLDKRGANFSDRPRFILFEEMGWGRILSFLPWGPKFRQHRKMLQRSFQKSSIIGYRSLQESEAAILLRSFISSPSTWENSLRRYATAIVLRAGFGIPLLSKDSLWITIAEDASYALGHGGAPGGTPVDFFPFLRFLPSMFHDRSLRFAHDWRWAIKKIHDDPFAAVSALAPGERQPSLITTLLAQRQVEIDLGQTPTLDEADIKGAAAAVYAAGQDTTWSTLVVFILAMVLRLDIQRKAQAELDKVTGRGRLPTFADRPSLPYLDLVLQETLRWIPVSPLGVPHRSLKDEIYRGYLIPAGSYVFANARAMTHDPAVYSDPETFNPDRYLPRSEGGSDEPLPNGHFGFGRRVCIGKHLGEASVWIAMANILSTISIDRETCEKGFEIIPPVKLTNGLTSHPQYFPCRIRLREQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMG5</accession>
    <name>A0ABR3YMG5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mitochondrial 54S ribosomal protein rml2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RML2_1</name>
        <name evidence="7" type="ORF">Cpir12675_005953</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000234">
        <property type="protein sequence ID" value="KAL1889035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="entry name" value="Ribosomal protein L2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_uL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005880">
        <property type="entry name" value="Ribosomal_uL2_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_uL2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_uL2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Ribosomal_uL2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01171">
        <property type="entry name" value="rplB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="RIBOSOMAL PROTEIN L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL2 RNA-binding" evidence="6">
        <location>
            <begin position="105"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL2 C-terminal" evidence="5">
        <location>
            <begin position="208"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="318" mass="34902" checksum="1AEF6378687F594C" modified="2025-10-08" version="1" fragment="single">MITPRVSFALGQLGRFMSPARSPAFARLYSAASTTQQTPAPDVQALPEKTAASGPQSTKEGVFMRTYKPTSPGIRHLKRPINDHLWKGRAYLPLTFPKKGHSKGGRNNTGRVTVRHRGGGVKRRIRIVDFDRRRPGPHTVDRIEHDPGRSAHIALITEKATSRKSYIVAAEGMRAGDVVQSYRSGIPQDLLKEMGGVIDPGILAAKTTFRGNCLPVHLIPVGTMVYCIGSFAKGPAKFCRSAGTYATLVSKEEETREDGTKVMTGKYVNVQLQSGEIRRVSKDACATIGRVSNPHHQFRQLGKAGRSRWLNIRPTVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMP9</accession>
    <name>A0ABR3YMP9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_005899</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000229">
        <property type="protein sequence ID" value="KAL1889117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1889117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="51" mass="5809" checksum="DAE7523381E7E789" modified="2025-10-08" version="1" fragment="single">MVPGAEDDEVLVKEQRRDSRDFEYTAVIAEVMKISLKQMGLKNKDIVVDPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN50</accession>
    <name>A0ABR3YN50_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Autophagy-related protein 27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="primary">ATG27</name>
        <name evidence="22" type="ORF">Cpir12675_005667</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle membrane</location>
            <topology evidence="2">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Golgi apparatus membrane</location>
            <topology evidence="4">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Preautophagosomal structure membrane</location>
            <topology evidence="3">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ATG27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000206">
        <property type="protein sequence ID" value="KAL1889763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.130.10">
        <property type="entry name" value="Mannose-6-phosphate receptor binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018939">
        <property type="entry name" value="Autophagy-rel_prot_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009011">
        <property type="entry name" value="Man6P_isomerase_rcpt-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044865">
        <property type="entry name" value="MRH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15071:SF13">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15071">
        <property type="entry name" value="MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09451">
        <property type="entry name" value="ATG27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50911">
        <property type="entry name" value="Mannose 6-phosphate receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51914">
        <property type="entry name" value="MRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0072">Autophagy</keyword>
    <keyword evidence="17" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="15 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 20" id="KW-0732">Signal</keyword>
    <keyword evidence="8 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="20">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046271626" description="Autophagy-related protein 27" evidence="20">
        <location>
            <begin position="25"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="MRH" evidence="21">
        <location>
            <begin position="26"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="103"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="118"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAL1889763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="357" mass="39176" checksum="C93CD48D31D3D688" modified="2025-10-08" version="1">MRWSLKNVAATGLLLAAISTLAEASLQCDSILANNHKYDLSPLRGPHSVVTTITEKNAVYNTTYTIDLCAPLKRVNDGSIPAREQCPEGTRVCAVQRALHAKGDSENVSSDDDGDGDDKEKDKSSEPYIREAVPLAGALESLGGAAFEYTTTKLDGQENNGEGFLLNLPGGVFPLDVPHKEQFPKKTVVRFLCDKEKTGLEGEWQAEVEYANSTSSSEDNKSAKMHKARNDAKDVEKQFVNDAAALLFDSYQNEGPDATGTLHLTWKSKYACRSVPPTGGTQGWGFFTWFIVLAFMIISAYLIFGSWLNYTRYGARGWDLLPHSDTIRDVPFLMHEFTRKVLSTVQNSGSRGGYSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN62</accession>
    <name>A0ABR3YN62_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Vacuolar protein sorting-associated protein 13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">VPS13</name>
        <name evidence="9" type="ORF">Cpir12675_005643</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000204">
        <property type="protein sequence ID" value="KAL1889778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026847">
        <property type="entry name" value="VPS13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056748">
        <property type="entry name" value="VPS13-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056747">
        <property type="entry name" value="VPS13-like_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017148">
        <property type="entry name" value="VPS13_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026854">
        <property type="entry name" value="VPS13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009543">
        <property type="entry name" value="VPS13_VAB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16166:SF93">
        <property type="entry name" value="INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16166">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25037">
        <property type="entry name" value="VPS13_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25033">
        <property type="entry name" value="VPS13_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12624">
        <property type="entry name" value="VPS13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25036">
        <property type="entry name" value="VPS13_VAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037235">
        <property type="entry name" value="VPS13_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Chorein N-terminal" evidence="5">
        <location>
            <begin position="1"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="domain" description="VPS13-like middle region" evidence="6">
        <location>
            <begin position="1153"/>
            <end position="1984"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 13 VPS13 adaptor binding" evidence="7">
        <location>
            <begin position="2059"/>
            <end position="2639"/>
        </location>
    </feature>
    <feature type="domain" description="Intermembrane lipid transfer protein VPS13-like C-terminal" evidence="8">
        <location>
            <begin position="3187"/>
            <end position="3293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="427"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="458"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="848"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="901"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1082"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1448"/>
            <end position="1500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1647"/>
            <end position="1669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1819"/>
            <end position="1877"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2711"/>
            <end position="2740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="427"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="913"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1082"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1448"/>
            <end position="1457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1832"/>
            <end position="1841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1843"/>
            <end position="1859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="2722"/>
            <end position="2734"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF25036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF25037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1889778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="3317" mass="369731" checksum="58CE583CE8964279" modified="2025-10-08" version="1">MLEGLVAGILNRFLGMYVKNFDPGQLKVGIWSGDVKLRDLELRREALDQLKLPINVLAGHLGELTLVIPWSNLRGAPVKVLIEDVFLLASPKEQSNYDPDEEDRRQLRLKMERLESAEILRDRNREGLSQEEEQKTQSFTQSLITKVMDNVQVQIKNIHIRYEDSISAPGHPFALGITLQEFSAITTDSGWKPMFMQDSSDTTHKLASLEALTVYWNTDTELMGTGRDFNPDQDELLPHITFVEKFRLMIANHAIESRLKHQYILRPVTGQAKLKLDKTGDRRIPRFHADLLFDEIGLVLDDEQYRDGLMLVDLFHYFVRHQEYLRHQPKVSVKEDPRAWFRFAGNSVLNKIHERNRKWSWDFFKERRDDRLLYIELFKKTKKNIMLEPEEGEDLQRLEAKLGYEDLRFWRSLVYNQMRKERSLAFATQQSNAQTHPSNQKQQQGGWMAWVWGSKPSDEIENEEQNQEPSENTLITDEQRQELYDVIDWDERTALAETIDVPRNSIKLQVESSLRTGSFTLRRKSHGQFKELMSLHFDAFKACMLQRPDSFLAQVTLGGFRVNDSTTPDSLYPEIVRVKDALSLRAADMMAVYNNKPTDPFFYLELENNPIDREGDVALVMKLKPLEIIWNPNFAVGISEFFRPPERHMESITALMESAGATVVTFREQTRASLEFALEEHKAINANLDLQAPLIIVPLSTSTKSSPCLIVDAGHVNVSSKLADKEMMNFIHAKQRQMYTDEDLKRLESAMYDRFLVTLSSTQVLVGPSIEVAKKQLADETDPLKLHIIDRINIDLIVELSILPKAPNLTKIKVHGHLPMLHARLSDQKYKTLMKAIEVAIPNLDAVANQGSDDRDKGTRKFGSRRGSHSSFMSALEQPLPVSTRRPSLFLSVRPPAIMEDDLHLDDNDNDNESASISSDSKSKASSEVSEQLRLQQRNFQFTFKIDYLKGSLCRSDPNGQLPDQLLVELTAENFDILFYNRPCDLVAEVSLGSVTLDDFVVENTPPEFKAIVSSGDTEDLLQNRSLVQIKLTKVSRESPEFLTVYEGIETNLSISVSTINLIVTRKTLLTLLDFTLTTFSGNSNESGSSLPETKPPTRPSLRRLSIMSLSSDANLVAGGLSPAIVVPTSPTPQATPSSIKIKAELKSIRLILNNDGTRLATLALNHADVNLFMVGPVMRLNAKLGDFSLVDDVNTHLPADSSLRRLISVHGDDLADFRYETFDSNDVSNYPGYDTSVYFRAGSVKVMFVQEPFRDIVAFVVKFGQMQALYNAARQAAASQATQIQHSNSRMRYDVVISTPIVSFPRSMVVKSQRDDVDVVVAYLGEIYAQNNFVPVSKEITTDVATVITAGIRNIRLTSNMVYPGGQSEELEMIDHVDLNFKMTSVEHRPGSLRPDMEIEGSMSDFNLRLTQFQIQFLLEVSQSVPTVFIAVDSDVLESSEDSKSSLSLPVSAALPPSTPAAGDEGSKDGEGNGDVAVPADDSIAIDSQPSSSLGPELRTDMSSWTRLDLVFRVKTIGLDLIAAQENCPVRDVKAAALSRFSLNESEVKFKMVSDGSIEAELLIQSLTIHDLRSQNKNKFRRIMSPRSEAVKQLMSTVTISGGQDRTMILVITLDSPCLIFALDYLFAVNKFLTVSLQPPSLIGADPDVRPQLPSPMSNKKDGNPVSLPYSRPSISTAQSTSKAIDPVPAAHDADTDKGTLNVVFRVNIIDSQLILIADPLSTSSEAIVLGTRQVLLSKQNATTFQVSEVSMFLCKMDHFDSSRLRVLDDFSVQVAMDNSKANVTSIDLAVDPLILRLSFRDIYLILQILAKASELSNDRNADCDPPTDGGAAGKSGEGGLPSSSTDNPTKEPPSSSKAIAPVIDSGGDATTRNQNQAKRIEQLRVSFSEVRLVLIGEGHELPMLDTAFGAFTANVDNWSTDLKAGVSVEMYANVYNFSKSAWEPLIEPWQTSINVDRVSETGLLNIAMDSSKTFDVTITTATVQLAMASMGILSKYKQAVEKPRGAEAPYRIRNYTGFDITVTSQSTTAAAETVEADKKITAHLNDGQETPWCFEPWEKMREIVSSDDRSATVEITLEGSGFDPIRNVTLNREGEFLFALRPRVENVLHRLMVEVVLESDYVKYVTIRSPLVFENNTQIPLEIGVFDIDTGDLLKIEQVAPGAKAPAPIGAAYSKSMLIRPDSGFGYEWSTATIGWRDMMGKPTRTIMCKGENGNLFYFQVAAQYDKTNPLTRNYPYMTIKVSPPITLENLLPHDFKYRIYDKNTQRDWCNFLRKGGVSPIHVVDLSHLLLLNIDMQDSVFKPSDFAIINSGTSSKDFSQERRLVCRDAKGLNLTLNLLYEKIPDGGGAFKVIIYTPYVILNKTGMELLIRARGFMQNAKVAAGQSHPASDVRNLRDEDMKAQPLMFSFDNDDHRNRAFLKLGTSDWSKPQSFDAAGSSTEVVLPSGDSHSKNTEISIGLAVESGVGKYRLTKIVTISPRFIVINKLGEDLRAREPSSSSILILKPCLLEPLRFMSKSATKQLCLAFPGINNPWSSPFNLSDLGTTHIKVNKDGQGHKLVRVEILIEGATVFVHLAYETRNWPFSMRNESSAEFTFWQANPYIDEDGIEAQSGWKPIKYRLPPRSMMPYAWDFPAASNKEIIICAQGTVPGARRNLERHVQLSEIGTQLPMKYGLPNGGQEVIDISVAADGPTQTLILSNYKASRSKYKGQTSRDVIPRSSTSSSVSGSAAAYETKDQETGTTFSAHMNLSGVAISLINASHKELAYVTFRGVQLRYHESQTYQTASLGIKWIQIDNQLYGGVFPMLLFPSVVPKKTNEIEAHPSLHMMITRLKDESYGLLYVKYATVLLQEMTIELDEDFLYALMDFASSSFSFISDGDSSLASTSAHSNGKLCEESLDIPQPKMEQAGNDIYFEVLNIQPMQLNISFMRTQVVNTTSDMGSHNPVTFFINMMTMAIGNVNDAPIRFNALLLENVRVSVPVLMQNVTSHYTQEALYQVHKILGSADFLGNPVGLFNNISSGITDIFYEPYQGLILNDNAEEFTLGLAKGATSFIKKSVYGFSDSFSKVTGSVAKGLALATLDKQFQDRRRITRARNRPKHALFGVTAGANSLLTSVASGVGGLAKKPWEGAEQEGALGFLKGVGKGVIGFATKPAIGVLDLASNVSEGIRNTTTVFDGSELEQVRKPRFIPLDGIVRPFNDREALGQYWLKQVDNGRFFDEKYIAHLELPREDLVVIVTFSRILVVWARKLNSEWDIPLKEIQTISKERTGISVVLKGGANGPFIPVTDESGRAFLYRMVAVAVEEFNRKFRTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN97</accession>
    <name>A0ABR3YN97_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005687</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000208">
        <property type="protein sequence ID" value="KAL1889683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="535"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="562"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="586"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="653" mass="70809" checksum="CEDA87F2E00E4E08" modified="2025-10-08" version="1">MNVTRSTQTLIEAFSALASEVQNLTDRKTILEHKLRFAHEQFQYLADKYAPAAPEISETISKLQLPATYIDHPSVKDASVPLPRRNGSALNASHQIALLIRDGRRAASQLAVSLPTSSPTDSHTHAYAHAPAHKSVSATAHAHTHPASLSSIKETTAHLQPTVTSMSTVLEQDFTVVGKKGQLECPFSAPRSVRQPPAMTSNTMELPSHSDKQEKEPGHSEVIKQDNGHEKHGHQDPICASMVAEESKSHEDPSATCPIRYLDKHTPEEIAQYVEKHKHQIPRSHEICVRRYQQSDEQVRKLDAKYGSLVSMIEGLSQLHKPMLASEEAALEELRTQEKRLHEGVGENDDGDSIGHGYAVVGGRDVKSKTQRVEQWAQAVGQSIGTNADTDPNAITVDDEDGDRGRVSSLSDQPILKDVRVGESPSRPWGIPVPVPEGPPAEYGDIASNQSSLPAPANPAVTTCHVGDAGLKYADANAITRKRDKPKAGVYSDLRAQAETSSKGGMRKCPFDHAKLAAMGISRPPMTAAVAAEAKLPPPTPQPEMRPSCQAQYAPPPPPLLETPEVTTSPTLPTSQAKYDSKAPASDTSHQPEQQPQQAPNFSQLPANANIFMPPIGTKESPQMVFNGPVFIGYSVEDAVQLIRQFQMGAQQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNG8</accession>
    <name>A0ABR3YNG8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_005775</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000215">
        <property type="protein sequence ID" value="KAL1889467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46118">
        <property type="entry name" value="PROTEIN ABHD11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46118:SF4">
        <property type="entry name" value="PROTEIN ABHD11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="60"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="313" mass="35203" checksum="F9FB13BD8860A621" modified="2025-10-08" version="1">MSSTLLSSARLCWKHNVKATYFHTSTAKTGPIATLFENVPTVQLSFEIQHPPNPLREPRPIVMMHGLFGCKKNNRTISKVLARELRRPVYNIDLRNHGDSPHADRHDYISLAADVHAFISHLEMDKPTIIGHSMGAKTAMTLALAAPDAITDAILVDNSPLDQALGSDFAKYIQIMELIERSNVMTRSEADTILAPYEPSLPIRQFLLQNLYRPTHGASFKFRNPLAVLAKSLNHMGDFPFKTPREARFKKPSLFVRGTKSSYVPDEVIPLIGDFFPRFRMVDINAGHWVISESPAEFKDAVVEFLNRDDGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNT7</accession>
    <name>A0ABR3YNT7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Thiol methyltransferase 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_005560</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000197">
        <property type="protein sequence ID" value="KAL1890019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008854">
        <property type="entry name" value="TPMT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32183">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32183:SF6">
        <property type="entry name" value="CYSTEINE SULFINATE DESULFINASE_CYSTEINE DESULFURASE AND RELATED ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05724">
        <property type="entry name" value="TPMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51585">
        <property type="entry name" value="SAM_MT_TPMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1890019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="285" mass="30026" checksum="BB44204101957610" modified="2025-10-08" version="1">MATPPHTLAESFADLEFSQHIGQWDAFWVDGTTPWDRASASPALAEALGMPEVLVAGEASAPAAASPTSTPQRKRALVPGCGRGYDVLLLASYGFDATGLDASPKAIVEAKETAHALADDPAYALAPGVTQRGSVSWAASDFFTEDLVQALGGQFDLVYDYTFLCALPVAVRPRWAAQMARLLSPTGRLVCLEFPIGKLPATGGPPHGLQSSAYMALLSAPNAEVVYDEAGEAVHTSPGGGRGLRRVAYFKPKKTHAVGYSPDGSVRDNVSVWGHQLGYADEELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNZ1</accession>
    <name>A0ABR3YNZ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8035 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005678</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000207">
        <property type="protein sequence ID" value="KAL1889700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058348">
        <property type="entry name" value="DUF8035"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26118">
        <property type="entry name" value="DUF8035"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8035" evidence="2">
        <location>
            <begin position="505"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="457"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="557"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="754"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="823"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="239"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="557"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="623"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="756"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="823"/>
            <end position="839"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="848" mass="96858" checksum="838A51E93989C5D2" modified="2025-10-08" version="1">MGRRDDNNEGLAYGESFEGGKRKTLKQALRDVDEKMGGLLRRGESKDGKSAANDARNYRPREQSPDGHGTRNRRYSIDHDRQRSPSPYYKSNAGYPDERDRPAFRDSENPHDVPERLRKPSQHPPPFTDDRSRPPSRSPPHFIGFPDRPISRSPDRIRLYRSNSDLGRQQGMPPSHVEFVQRADSRPPSPSRFRNPEWAHRGDACSPDPYADGAEFSDDVRSRVHAALHSNGNYNYPVRGSRQSPRSRSYSRSPSPPPVHHAAYRPASPDSRYSNVYPHPVPSPPLSSRVGQSAVHHSRSPSPSRHRRQDSMPRYRPPGHTGSIPPPPLMRRSSSFDSYNNYQRLSARAQRDYIREKEEERESSRRDEVPYLAAPRSANYHSKFKAPSVVFYDNKPTTSELDLNQKPAIIDQQTSFQSRRRRNSSPGRRFDYEPDFYGYSSDEGRRRYSSRDRMGSFDHYAEDDGGLNAEGRKRRASKYAYSDRHPSPDSASRVGRTLGRSEVLKRGRTKMPFKYTEEQAIQDKGYPYHVKGHSFIIEYALKQPQITELLTLSQQYRERGDEKNNVRETKSRYQTKDGHVVERRDRESFHEEIVFSPSRESKHRSESKHRSESKHRSESKHRSESKHRRHRSSSSISLSPPPQPLRVSYPMAAPMPVAIRTDAQIVDAAPPGAYDVSNSVLPFVNTVVSPVENMPPYTAIAPPLTPVYGSSIGHTYPGSIQPGIDPSIEAPGMYLQDHSAMAMIASSIVSVDSSRSRSRTCLHHRSKSKRGTSRHRSRHKSRNRHSGARSKSRHRSRSVEDMMVWAERDSHGRLVVHENTVHEVKEKHGGTRIELDSKGRLRVSRPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNZ3</accession>
    <name>A0ABR3YNZ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ribose-phosphate diphosphokinase</fullName>
            <ecNumber evidence="3">2.7.6.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PRS4</name>
        <name evidence="13" type="ORF">Cpir12675_005698</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15609"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribose-phosphate pyrophosphokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.1" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000209">
        <property type="protein sequence ID" value="KAL1889618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000842">
        <property type="entry name" value="PRib_PP_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002320">
        <property type="entry name" value="PRK01259.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210:SF32">
        <property type="entry name" value="RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01400">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00114">
        <property type="entry name" value="PRPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribose-phosphate pyrophosphokinase N-terminal" evidence="12">
        <location>
            <begin position="9"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1889618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="323" mass="35084" checksum="1B7E323588A903CF" modified="2025-10-08" version="1">MPTPMSNEIKLISGSSHVDLSGRIAKRLGIEVSKTMSLQYSNQETSFTMGESIRDEDVFIIQSTAPGDINDGLMELLIMIHACRTASARRITAVIPNYPYARQDKKDKSRAPISARLVADMLQTAGANHIITMDLHANQIQGFFSVPVDNLYAEPSVLRWIRENIHVADCVIVSPDAGGAKRATSIADHLNTAFAIIHKERPRPNVVGRMTLVGDVKDKHAILVDDIADTCGTLAKAASVLKEHEAKSVVALVTHGVLSGTAIETINASQISVLVVTNTVPLGDKLNRCPKLRVIDISPTIAEAIRRTHNGESVSYLFRNVPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPC5</accession>
    <name>A0ABR3YPC5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Hyaluronan/mRNA-binding protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005539</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000195">
        <property type="protein sequence ID" value="KAL1890088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="109" mass="12035" checksum="2E7B8B6A8D5E511F" modified="2025-10-08" version="1">MPKFYGKAGYTNTDPKNTKKNGNGKANWGAVGDDLLDDEFNFTHTRRRSNSNSFSNTVRSFKTKFDVNEPEPVFEEELHGPLAEGEDDINPLSKSTDAEESGSTASSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPH5</accession>
    <name>A0ABR3YPH5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_005477</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000189">
        <property type="protein sequence ID" value="KAL1890258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1890258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="224" mass="25204" checksum="BCDAA8385F765B68" modified="2025-10-08" version="1">MRSGPRSHLCATSHSVHMTYPGLAMFDIVHTLGADSMFGETVRRLRALRRLPTSLVLPEGWGTELDGLPKELAALLNLNPGETTATGNTYHTLATVVALCLECEEASENILMCFAFLRAMDARFQQLLNVKDLPALVLMAWWYARLVKFDSEEILRRARVEGQDICVYVESWGHMSSDIMTALEYPKKVLGVNQDFIDNMRRKPAKISLKPSLCQHPHGFKKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPU5</accession>
    <name>A0ABR3YPU5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="6">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">UBP6</name>
        <name evidence="10" type="ORF">Cpir12675_005408</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000184">
        <property type="protein sequence ID" value="KAL1890394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16104">
        <property type="entry name" value="Ubl_USP14_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044635">
        <property type="entry name" value="UBP14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982:SF1">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="3 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="8">
        <location>
            <begin position="4"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="108"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="373"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="536" mass="59416" checksum="844C9AE8736131A9" modified="2025-10-08" version="1">MSSFTVSVKHRGTKYDVEISDDCTSNDFKLQLFSLTSVEPDRQKVIIKGSTLKNDVPMVTLGLKPGQTIMMMGTPGDDPSGALVRPKEAPKFAEDMGIDDITALGIPRGIYNSGNTCYLNSAMQMLRSMPEIVTGLPRLPKSGGEMASQRMYKEALKLLDTLKSGKETLNANNFIETLRNAYPQFAEISKRGHGYAQQDAEEAFSQVLTVLKMNDATTESGGRSMIDKYMTGTFQTLTKCEEEGDNSASVVGSEEFSKLSCHITSSINHLQDALRASFTAQIEKRSEVLGRDAMYTKTMLISRLPRYMTVHFVRFFWKRDTQKKAKIMRKVTFPAEIDLTEHCIPELKAKLVPVRDKVREIRKDELDIERARKRRKTTTVAEPEVSRREPPAASASNTTPGNDDGDTEMVETFKTDAQVDAEKDAVLQKAKDELKAIIDPELLADDGANQTGLYELSAIITHQGASADSGHYTAYVKKDPVLDPKTGKMGSDGNWWWFNDDKVSEVPAEKIEGLAGGGETHSALVLMYRSVPLPLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ10</accession>
    <name>A0ABR3YQ10_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_005418</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000185">
        <property type="protein sequence ID" value="KAL1890373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028209">
        <property type="entry name" value="LAMTOR1/MEH1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15454">
        <property type="entry name" value="LAMTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01262">
        <property type="entry name" value="LAMTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0519">Myristate</keyword>
    <keyword evidence="4" id="KW-0564">Palmitate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1890373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="166" mass="18058" checksum="0D0F37FFC1611B17" modified="2025-10-08" version="1">MGAFCSCLGLSRNDYYDEDEERRLLEDDNVVGGQYGVLNDTPIMATEDGVEARQEFEALQRVVAKASDNMVDIFEIGDSARPTPAPFAYAGQENRLMRYRNLLSKISGTDDDTDTVHLESALPPVHVDAAATTPIELSSTLYSTTEQLDKEAALVGTFADAAAAMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQA4</accession>
    <name>A0ABR3YQA4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SHSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_005527</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000193">
        <property type="protein sequence ID" value="KAL1890112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06464">
        <property type="entry name" value="ACD_sHsps-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031107">
        <property type="entry name" value="Small_HSP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11527">
        <property type="entry name" value="HEAT-SHOCK PROTEIN 20 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="5">
        <location>
            <begin position="87"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="138"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="203"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="225"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1890112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="319" mass="35306" checksum="B580C24669C01DC7" modified="2025-10-08" version="1">MVYFAPFVSPDAFSPFSVLNEFESPVYRQPLALSTPIFAAPVYTPRYCRPRYQRAPVRRSVASPLSLEMPSTYRAITPRLVVKPSSMSKPALQPKFEIRNTADAYELHGNLEGLDKKDVEIEFVGPQTLTICGRVQRNSSPTVPATVDKTVNAEGQDTQMSVDIEPETAPTAEPETRAPRSPSPSTYRKATVEDSPDEDDHLSITSMTSTRSSSSAGEKRPIDFPAPTKSPKVVKVSQPSSPAAERAIFKALDPSVPAKKTAPKNTGNWESERSFTQFSRTFTFPERIRQDRVHATLNDGILSVVVPKARQEAHRVIIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQG4</accession>
    <name>A0ABR3YQG4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_005705</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000209">
        <property type="protein sequence ID" value="KAL1889624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1889624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="100" mass="11122" checksum="5F39F77EBDC492FE" modified="2025-10-08" version="1">MAPSPRNFSTASRAYPSFFPMLNTAPKISRKVLTPVAMVLAAGIVAKQYTDNAAERQAQLDLQDAKMRAHNAQWLDAYGDRSDLASLEKAMMAYSKREQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQK6</accession>
    <name>A0ABR3YQK6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aspartic proteinase</fullName>
            <ecNumber evidence="6">3.4.23.25</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">APR1</name>
        <name evidence="6" type="ORF">Cpir12675_005336</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.25" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000179">
        <property type="protein sequence ID" value="KAL1890583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047090366" evidence="4">
        <location>
            <begin position="19"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="5">
        <location>
            <begin position="88"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1890583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="399" mass="43301" checksum="AAAC3E56C8FA5E48" modified="2025-10-08" version="1">MRGTNAFVVAAMLGTASAAVHTMKLKKVPLTEQLATASIEEHVDALSQKYLGEHQFNLADAMFNTKTSNFAMNSGHPVPVSNFMNAQYFSEITIGTPPQTFKVVLDTGSSNLWVPSSQCGSIACYLHQKYDSSQSDTYKKNGTKFEIHYGSGSMTGFVSQDTVTMGDIKIKDQLFAEATSEPGLAFAFGRFDGILGLGYDTISVNGIPPPFYNMVNQGLIDKPVFAFYLSKEDKGESEAIFGGINKAHYTGDITYIPLRRKAYWEVDLNSIAFGDEVAELENTGVILDTGTSLNVLPSSLAELLNKEIGAKKGYGGQWSVDCAKKSELPDITFNLAGHNYSLPAEDYILEVSGSCISTFQGMDFPAPTGPLAILGDAFLRRYYSVYDLDKNAVGLAKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQM9</accession>
    <name>A0ABR3YQM9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UBC core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_005521</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000192">
        <property type="protein sequence ID" value="KAL1890182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23799">
        <property type="entry name" value="UBCc_UBE2J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="UBC core" evidence="3">
        <location>
            <begin position="12"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="367" mass="40584" checksum="94030B91B1A9ADBA" modified="2025-10-08" version="1">MAAAQPFNPRSPTMRRIMREAKELTDSPSADYTAAPLDSDIFEWHFTIRGPPNSAFSGGIYHGRIVLPAQYPLRPPNFRFTTPSGRFEVNREICLSISGFHEETWQPAWGIRTALVALRSFMETSADGQVGGIDASDSVKRSMAAASPSFRCATCRKTNAEIIGECEAAAAKHSGSSTPLVEVPSELKLAFKDELTSGKNPIPDQEEDTDEEARLAEGFVPTAAVDARPAAQLPFENVQAQPAPLAASHAYENQENNAFANQVQRHLQQHLQHHVQQVQQVQQVQQVQQQQQEQHQQSAAFNGQVRAQRQPQPHLQDFPQPVQPMNAYVANGDDIPKWIDMAIAGLVCLLATLLLRWGYLDGLLIMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQV2</accession>
    <name>A0ABR3YQV2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005305</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000177">
        <property type="protein sequence ID" value="KAL1890673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22676">
        <property type="entry name" value="FHA_SNIP1_DDL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050923">
        <property type="entry name" value="Cell_Proc_Reg/RNA_Proc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23308">
        <property type="entry name" value="NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="271"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="362" mass="41964" checksum="7C3DCBFA950248B7" modified="2025-10-08" version="1">MDIADNPPSSRSPIQNRTFELKKQVDDRQSEVHSRRGRRDREHDSRSHRHRDSRSEQSNRHRHNSHERRHNRERDCGREDSRAHVSSLRRSRSRSPHSHSHRHRERDDAERKSHKTQREKRHSQNRDSSAEADRKDERSSDRKSGAISKRHRRSRRSSPSRSHSPGTKRPVSRNSAPANRTALPSQESSWAVTRGEAPPTEKEKPNFNTTGLLAAESNSVQQSDGTIIRLKYTEPTDACKPRKRSRESWKLFVFQDKQVLDTIPLVEKTAWLVGREGAVCDFPEAHASVSKQHAVFQFRLKEKRNEFGDREDTVKLYVIDLESSHGTKLNSETIPTSRYVELRSGDVIRLGKCSKEYVVMMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR44</accession>
    <name>A0ABR3YR44_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_005245</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000173">
        <property type="protein sequence ID" value="KAL1890791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10209">
        <property type="entry name" value="OXIDOREDUCTASE, 2OG-FE II OXYGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10209:SF886">
        <property type="entry name" value="UPF0676 PROTEIN C1494.01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="6">
        <location>
            <begin position="170"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1890791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="363" mass="39831" checksum="B425C26A4164381A" modified="2025-10-08" version="1">MASSLANIPIIDITDDGLSEFDIGKALVDAAAEQGFIYIKNTGKVMPIDRIQKAFDISRILFKETSLDEKRRCTIQKNNRGWSDMQTEMLDPKTQKAGDTKEGFNFGEFKDGKPNQPIPSTIEPFEGDIKQIFGDCSSLAQRIIYLLGVGLETQPADFFSSVHTPEKGESGTTLRMLYYPAPSEVPVADKSVRAGAHSDYGSITLLFRLPGQAGLEILTRENTWAPVPVIPTGTETDPSPPILVNIGDLLSYWTNGLFRSTIHRVTIPSPATSDTTSPATVAGEAAGERYSVAFFCHPVSDTRLEPVPSTRVANFSGSTVDDNVNPYAQRKVMTANEHLFMRLRASYKDLYGSEKTPRQGPMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR70</accession>
    <name>A0ABR3YR70_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_005423</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000185">
        <property type="protein sequence ID" value="KAL1890377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1890377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="78" mass="8752" checksum="13728F93DCAA3890" modified="2025-10-08" version="1">MSVIFTTANSDEKCSHDWNEADYGLTEISPAVGRRTHFDAYQSIVWGLFGRLAPGEQIWARTTNSVLDDVGNHNTHKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRE1</accession>
    <name>A0ABR3YRE1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Symplekin/Pta1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_005396</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000183">
        <property type="protein sequence ID" value="KAL1890471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021850">
        <property type="entry name" value="Symplekin/Pta1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032460">
        <property type="entry name" value="Symplekin/Pta1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15245:SF20">
        <property type="entry name" value="SYMPLEKIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15245">
        <property type="entry name" value="SYMPLEKIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11935">
        <property type="entry name" value="SYMPK_PTA1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Symplekin/Pta1 N-terminal" evidence="5">
        <location>
            <begin position="91"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="307"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="422"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="573"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="336"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="432"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="443"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF11935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1890471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="781" mass="87166" checksum="0CC13DE16F2DAACF" modified="2025-10-08" version="1">MAGSASVDEQIRQLNDARKLVLADVKFYPDVVKGILPILQPNTLVELRRWGADFLAEAFATPALSVKEKETMQVSGVIDTLETVLNNPNEDLHVLRSIILACASIYPVTLRWTIENSYDNITWEKMMAIKSRIFAIWETASISVRICCIKFAQRVVLAQTPSIGLEAKRNDSMDVSLDRITANHALLDPRMMEAEAHGLLDLIMGTLQDSKINVVSGEGLLIDATLNCLAILVRGRQNIGNRILNIVLNFDPYQNATGTLSPKETVMMKSLVKTIRIFLIGFMKRDPQNPFSQRIHQRLEWLTARGSNATEDAGRKRPLEPLQQPHSDPKRQRTAQPPPSFPPPPPQQPEEDYETAPLGPGPHTLGDVFTLTKTASETVKNFDVHTLPPPLVSRIVISTLASISPHVLNRKIGDVRQRLEHLKSSVPPPLPSSTAVPPLVSTNDDDDDYEPDFDGSEDDDQTQNKMDCKSTQVVPPSNLEASLSLEAFKLATAPPLTQESATGMGQVALQQVFEDCVVVGDDSMVAKKSKVGWRQFAAHMGDRDSWITTLIRIASRGSSEIQHDKSIKSEIKTDNEIEDEDTKNSGVLTAKSLRPEGNPLTLNTDLRDMIFEYVMADFRKRIDVAVTWLCEEWYNDQIQLKYDQTRASGDGGRGRQYHQLVLHVLDGFLPYLHPGDRVLTRFLSEIPELSEPILTRVKQTCRDPTVVSLVLNSLLYLVMMRPPIKELALDAIQDIWLDVEDARNMAGKYLGKFRPEWLSAAIQNAENKTTTTNNEAEVPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRG6</accession>
    <name>A0ABR3YRG6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Copper acquisition factor BIM1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_005304</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000177">
        <property type="protein sequence ID" value="KAL1890672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21176">
        <property type="entry name" value="LPMO_auxiliary-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046936">
        <property type="entry name" value="BIM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046530">
        <property type="entry name" value="BIM1-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992:SF1">
        <property type="entry name" value="COPPER ACQUISITION FACTOR BIM1-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992">
        <property type="entry name" value="HYPHAL ANASTAMOSIS-7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20238">
        <property type="entry name" value="BIM1-like_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046460591" description="Copper acquisition factor BIM1-like domain-containing protein" evidence="9">
        <location>
            <begin position="16"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Copper acquisition factor BIM1-like" evidence="10">
        <location>
            <begin position="14"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF20238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1890672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="218" mass="21834" checksum="F0162CF15D56B1A2" modified="2025-10-08" version="1">MKFSVSLLLAASASAHFTLTDPKSIGFNDDNESESPCGGFSVTSRDNAVEFPSGGLSFTVVSTHAAADWTFKAALLNNTDDFQYLIAPVSQEGLGTFCLQNIPGPSSWAGQEGVVQIAQGATDGSLYQCVAVTFTDGNSGSKPSACTNSSGISISWNDLPSDSVIAGSSSSSNSISSSSSSTSTSSSSAASSSATSAAGQTVSSFGSAALLAAAAYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRW3</accession>
    <name>A0ABR3YRW3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adhesion defective protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005106</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000163">
        <property type="protein sequence ID" value="KAL1891098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029005">
        <property type="entry name" value="LIM-bd/SEUSS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10378">
        <property type="entry name" value="LIM DOMAIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01803">
        <property type="entry name" value="LIM_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="625"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="741"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="219"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="258"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="352"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="761"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="806"/>
            <end position="816"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="837" mass="92052" checksum="3AB737F6D5633946" modified="2025-10-08" version="1">MMTGIGTAFTGHPNAMPQHQHPGMTQGHPMGPGVPHPAGQPVGPGGMPGHMAMQMGVSGPGAQMNTSALMGTMPPGTAGAQAHSIPHIQAQMMQQQQAQAHAQAQAQAQAQAQAQAQAQAQAQAQAQQFSFANSNPQLHAQMQQQRLINQQQQQHRQQVMMAQQINGAGMHVGMMNPQQMALMQGRINPSHNSTQLIAHRIALQQQHQVAVQNQLNQANTSQSMQMGSQQMPMSMGAPMQPQHSAQGQVPGPHPSMHQMQQGQPQMQPQPQQPQQQQPQSQQQQAAQQTQQQASQQQQQAAQQQQQQQQQQQQQQQQQQQVAQQQAHQQQQAQQQQAQQQQAQQQQAQQQAQHQAQQQQQAQQQSQQPGPQPQPGPIPQQGPSGPGPQSRQPLAPPQVGAPGPGPQGGPVPNSAGPNHPQQILSQIHALGANQPQQQVIGMAPQMVMKNRGEDVKVQCLVKLMQFGEMLSAYPENGTMLYWENFVHQLFSQFGVFRIFIPSENNDQERHKQYDIPQSILARYFARHFESNVRSIQFILGFNTGHRLMPQNNMNVIENTRASFVYWLDNSTHIVTTGNIKVKFDGDQRIVAFEFFTTNYDEYISHQRVIEQAKPAHNWIKEWRQLNQPENKSPEMSKKPKPKQLKSPQTAPPDALGDFPAAQGKRSIPEGMLQFLEVAEVMMQMNPLFLFCQAQNETAPYRALEQYVGQFVMGNANNNAAPGMTAGTGTPRTPSFGMFPMGASPAPSHMNIPGSPHMMESPAMSQLQAPGLQMQKSQQGSNGPSANTSPASGKRRRQSTIKMDEDQQGTPSGGQQINGVPGKKPQTPRTANKRLKTGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSH4</accession>
    <name>A0ABR3YSH4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Kinesin light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005214</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000170">
        <property type="protein sequence ID" value="KAL1890818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45641:SF19">
        <property type="entry name" value="NEPHROCYSTIN-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45641">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="276" mass="30619" checksum="C24BA8582F57FDA3" modified="2025-10-08" version="1">MGKAKSTDASDLAFKVGKCLLKDGHTQESVIMNEYVVAMEEKALVVDHPSLLAFKHNTAVAYLKNGQVEEAISVFEHVLMTEENILAADHPYLLTSQHELGREYLDNGQAEKAISMLEYVVEMREETPEADDSELLMSQHELAVAHLNNSQVEKAIPMFQHVLVMQGKTLAADHSSFLASQHNLAVAYLKNDQNKEALSTLERRLVVEQKTLGVDHPLFLATQHELARVYLSSGHVAKAVSMLECLLLMQEKALAADHPSLLASQYELGRAYNTNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSI2</accession>
    <name>A0ABR3YSI2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histone deacetylase</fullName>
            <ecNumber evidence="3">3.5.1.98</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">HOS3</name>
        <name evidence="3" type="ORF">Cpir12675_005045</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000159">
        <property type="protein sequence ID" value="KAL1891228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141221">
        <property type="term" value="F:histone deacetylase activity, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd09998">
        <property type="entry name" value="HDAC_Hos3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053244">
        <property type="entry name" value="HDAC_HD_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47558">
        <property type="entry name" value="HISTONE DEACETYLASE HOS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47558:SF1">
        <property type="entry name" value="HISTONE DEACETYLASE HOS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="2">
        <location>
            <begin position="274"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="683"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="754"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="991"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="114"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="135"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="689"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="754"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="785"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="837"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="861"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="887"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="923"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="991"/>
            <end position="1000"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1010" mass="108194" checksum="290FEC6BD0103F89" modified="2025-10-08" version="1">MPPPSRPASSLRRSSLAATSSATTNITTAVPAPTSPYLGPPTLAVRTTGSSLSSVSPRTPTLRSSVSSSSLRSGTARPPPPSPSSRMQSSNSPAMSRSSSLGSRSNTPTLNRRTSTSSLHSVSGSTPIGTPTRRASASGSSALSPMARSPLALHAHPPPTIDEAPSAEDIAADHFRADLATHGSPEDRRTTELVVVLNDACYGHRFSRPRTSHNALNTIVERPERVRAAAVGVAMAYVRLGGRYADGHNPVHPRIHPTSINRIPFRVRKTDRKVPITAPAVTNVHGIKWMEELKIMCNSAEAKLAFGGKELQRPDVKRDPEAGGNSPAKFHEGDLYLCAESLDAFEGALGAVCEAVDLVFSAAPRRAFVGVRPPGHHCSTSYPSGFCWINNVHVGIMHAAMSHGLTHAAIIDIDLHHGDGSQAIAWQHNKRANSAHKNASAWKKSHIGYFSLHDINSYPCEMGDEEKVKNASICIDGAHGQNIWNTHLQPWKTEADFWKLYQEQYLQLLDKARKFLKSQAEKQTTAGVVPKAAIFISAGFDASLWESAGMQRHNVNVPTEFYARIAQDVVRLAAEDENAVDGRIISVMEGGYSDRALASGVLSHLSGLAGDQLQGSAAPPSAYQGLGAEMGLRIGLASSEVDTGADPQEALRSLHSYDSQWWSSSELDKIETLLSPMMVEPKKPKAANASPTYCSPTHASNARKVEPRLRRSISNLSINAAYSRPETPPPPDVQWEVAAHELVKQLIPLDRTTESCTHEDLNAEATRARKEKQPKSEPVTPVRMSLRERRAKPIAEVREVKEKENPASRAGRRRTVASTSATGPAEKPPNAARISRRVSTTSEIPPSTSAAGTREGPAPITISTRPSTSMTIRTQPPSTLNVKKSRPSTSMSSASAIASTAESALTKAPSRATRPSVPVQRLSAVSREPSRAVSVAASVSSASSSAATTRPSTTSPTGNEGIDPKQAADNSLDQITNGMRRIKINLITREQREARQRAEAEAGNAAGPRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSU9</accession>
    <name>A0ABR3YSU9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">EKC/KEOPS complex subunit BUD32</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">Atypical Serine/threonine protein kinase BUD32</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">EKC/KEOPS complex subunit bud32</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">BUD32</name>
        <name evidence="18" type="ORF">Cpir12675_005017</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. BUD32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000157">
        <property type="protein sequence ID" value="KAL1891333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022495">
        <property type="entry name" value="Bud32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03724">
        <property type="entry name" value="arch_bud32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12209:SF0">
        <property type="entry name" value="EKC_KEOPS COMPLEX SUBUNIT TP53RK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12209">
        <property type="entry name" value="NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06293">
        <property type="entry name" value="Kdo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="18"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00033194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1891333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="270" mass="30183" checksum="E954988E68D42C96" modified="2025-10-08" version="1">MTTQFEFPLPKCLEYPASAPPTLITQGAEGRLYKSTFVEPTLPCAVKHRPSKPYRHPLLDKKLTRARILAEARILAKCLREGVLVPAVYAVDEHNGCLTIEWIEGAPVRVRVNEWLATQKAVLPPLTENVEAAVMAAEMAQKTGLDAELRDVFRRMGFTVGSLHRVGIVHGDLTTSNMMLRQSQKQIEEKSLRGEVVAIDFGLASQSSLEEDRAVDLYVLEKSIGSSHPRAEHIFPEVLEGYKQGFKQAAMVLKRLEDVRLRGRKRSMIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT09</accession>
    <name>A0ABR3YT09_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Histidinol-phosphatase</fullName>
            <shortName evidence="8">HolPase</shortName>
            <ecNumber evidence="3 8">3.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_005044</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>L-histidinol phosphate + H2O = L-histidinol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14465"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="3.1.3.15"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 8/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the PHP hydrolase family. HisK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.15" evidence="3 8"/>
    <dbReference type="EMBL" id="JAWDJO010000159">
        <property type="protein sequence ID" value="KAL1891227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12110">
        <property type="entry name" value="PHP_HisPPase_Hisj_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010140">
        <property type="entry name" value="Histidinol_P_phosphatase_HisJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01856">
        <property type="entry name" value="hisJ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21039">
        <property type="entry name" value="HISTIDINOL PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21039:SF0">
        <property type="entry name" value="HISTIDINOL-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="PHP domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHP" evidence="9">
        <location>
            <begin position="1"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="291" mass="32729" checksum="F9D33D83E7C13057" modified="2025-10-08" version="1">MHSHSGQFCPGHGKDMLEVIVQHAISVGLKTMGLTEHIPRISPEDLYPEEHEASQRLRAVYPSLHILIGIEGEWYRPEYAAHMRALLADPAIDYFIGSVHHARGGIPIDYDVATYATAVQAAGYGSERGLYAAYYDDQLEMLQALRPRIVGHFDLIRLLSNNPARDVRAEWPEVWERMLRNLRFVVELGAWLECNTSALRKGLSEPYPARQVAEEYLKMGGRFTFSDDSHGTAQVTTNYARGLDYLESLGVIEVWTFKRTPPTVAGEKGTLEDVSVTLAEFRASLTPRTQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT67</accession>
    <name>A0ABR3YT67_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">3,4-dihydroxy-2-butanone 4-phosphate synthase</fullName>
            <shortName evidence="4">DHBP synthase</shortName>
            <ecNumber evidence="4">4.1.99.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RIB3</name>
        <name evidence="5" type="ORF">Cpir12675_005101</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18457"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="4.1.99.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="4">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="4">Binds 2 divalent metal cations per subunit. Magnesium or manganese.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Cofactor biosynthesis; riboflavin biosynthesis; 2-hydroxy-3-oxobutyl phosphate from D-ribulose 5-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DHBP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.12" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000162">
        <property type="protein sequence ID" value="KAL1891132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008686">
        <property type="term" value="F:3,4-dihydroxy-2-butanone-4-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.870.10">
        <property type="entry name" value="DHBP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000422">
        <property type="entry name" value="DHBP_synthase_RibB"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00506">
        <property type="entry name" value="ribB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21327:SF18">
        <property type="entry name" value="3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21327">
        <property type="entry name" value="GTP CYCLOHYDROLASE II-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00926">
        <property type="entry name" value="DHBP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="YrdC/RibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0686">Riboflavin biosynthesis</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1891132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="232" mass="24901" checksum="A6F78010CF913C96" modified="2025-10-08" version="1">MSSTTPIEASAFDTIPDCIAAYRNGEFLVVLDDPSRENEADLIIAAEDMTTEKMAFMVRHTSGLICAPLPALRTAALGLPQMVESTQDPRGTAYTVSVDAADPSVTTGISAYDRALVCRVLADPASTFDSLRRPGHVFPLRAREGGVRERRGHTEAAIDFCRLAGKQLAGAISEVVDDGAEVSGQAIRTNGGMLRGKDCIRFARQYGMKVCTIADLVTYLEKTEGKLNSNEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT84</accession>
    <name>A0ABR3YT84_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">tRNA (Cytosine-5-)-methyltransferase ncl1</fullName>
            <ecNumber evidence="13">2.1.1.202</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">NCL1</name>
        <name evidence="13" type="ORF">Cpir12675_005047</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.202" evidence="13"/>
    <dbReference type="EMBL" id="JAWDJO010000159">
        <property type="protein sequence ID" value="KAL1891230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057285">
        <property type="entry name" value="Pre-PUA_NSUN2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057286">
        <property type="entry name" value="PUA_NSUN2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023270">
        <property type="entry name" value="RCMT_NCL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018314">
        <property type="entry name" value="RsmB/NOL1/NOP2-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22808">
        <property type="entry name" value="NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22808:SF1">
        <property type="entry name" value="RNA CYTOSINE-C(5)-METHYLTRANSFERASE NSUN2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25376">
        <property type="entry name" value="Pre-PUA_NSUN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25378">
        <property type="entry name" value="PUA_NSUN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02011">
        <property type="entry name" value="RCMTNCL1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01153">
        <property type="entry name" value="NOL1_NOP2_SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 10 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="12">
        <location>
            <begin position="67"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="491"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="823"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="508"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="543"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="823"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="364"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="186"/>
            <end position="192"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1891230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="861" mass="96777" checksum="4854014D35E987A0" modified="2025-10-08" version="1">MGRGGRRRGGRKGGGRGGRNNGNDREAFSANNADRRVSYPQIVKENEKLEKYYNDMLQIPEDERKEFWEALRRELPNSFRFCGSKGHALAVRNLLQTRYIPEITRIKHEDGNFVQPPKPVPWYPDGLAYDMTTPKNVVRRFPPFAAFQKFLVSETSVGNISRQEIVSMIPPLLIDLKPGMSVLDLCAAPGSKSAQLLELVHAGEEARIKKVLRQHATEDGLALGTETEEEANADLSADPSDQGRATGLIVANDMDYKRCHMLVHQLKRFSSANLLVTNHDASAFPSIKLPDSYSDRPGKRSYLKFDRILADVPCTGDGTLRKNMTMWRSWTPNNALGLHIVQVRILVRALQMLKVGGRVVYSTCSMNPIENEAVIAAAIDRCGGPEKVGILDCSNQLVGMKRKPGMKTWQVMDKSGNWWNSWQEIQDKAAADSTWEAPGKITEPMFPPPDGSRCADLPLERCIRVYAYQQDTGSFFITVLEKKAEIRARNENTPKDATVATSAMTAAEGDDETEVEAATETEAETANGKRKLDEVEAVNEMDVDAKKVKTDDEDSRDASETPKAEAETKAETKTETKTETTTVASAEPKERRKDTSIRYEDPFKFLAPDHPVLDEIFKFYHLSPRFPRDRFMVRNATGQPLKAIYYCSTLARDILGENDLKGVKFLHGGVKMFVRQDVPNPDVCRWRIQSEGMPMLHGYLGEGRVVHLRDRETLRRLLIEMFPRISDGEWQKLGDIGERVRDMSMGCYMLRVELDADPNASPEALADEAALREPMVLPLWKSISSLNLMLPKEDRAAMLLRLFNDNSPLVNNSLLRQKYIQKQQEEEAKSKKTEAEADAEAIPAIEEDINVEDAPTPEGMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTA1</accession>
    <name>A0ABR3YTA1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_004936</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000152">
        <property type="protein sequence ID" value="KAL1891564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF4">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="45"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="103"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="695"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="746"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="705"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="752"/>
            <end position="766"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1891564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="904" mass="99968" checksum="46D5978E5C362733" modified="2025-10-08" version="1">MGSPTKVTIPSLPSGLPAVTIPRAQVIIERLPQQKNVNTRREVMNCKTCRRRKIKCDRVAPCCGACQLLGNICVYDAVPKKRGPKTDVIESLLKRVGGLEERLREKTAKEPSSGVRHKKSVDGCASVSDAEEAPARGPAASNENEFRPSKRRATASSNADEGIETTPSFSPSSAICQSPRNLFSPLASSEDEQAASASPRELLDTYFQKIHGKPYYILDEISFQQQKQRGKVPAHLSNAIYAIAARYTNHAHGVQASLQMSDYYASKARSQIDIDEPSIESLQALLLLVLVFTASGKGKKAYMLMTSAVAMAMALELHRESTVQTNFPFTDTEVRRRLFWTCYIIDRFMACGSNRPHFIVDSAAIALQLPFRVTANGPSITKQGNVLAQDGHSMRQFLESNNKHRCSYGLLVDITKILGFTSQFITACTSSSASSCYPWDEASEVSRIRRDLVAWEAETRDIFSSMGTILAHPEANIIMLSKLVYHTVYCLTYRPFLPMEVTELHQPSQHLAWQIDAANNCFLHANSIMELVELSQQVGNIQFPPFVGQAICVAGTIHMHGVYYCKDNARASQSRFYKSEEFLKREMACLEKLKHSWPAIGYYRKTLQELHKKHSELVDRRAGNASRYISPLQGRDFFDRYSTSPGGQVFQFDAASLTLPESASDGLVEDETTGETQLKQKVPSVLQSCALKRKLSASSTEHTPSGSSRAVSVRSRSSFSMARGSSLPYLESPRYTTSPALHLVSSPDMHQPDTSCEEPSNTNNSRTIIPGVAMPNYTLSSSNSYYHPIVDGGRYHCQDQYTNPYRMMGAAEHTPEYVPHTTFLLSGHSIASNDSISAPASYGSLLSPSALSSAFYWNDPSTGCYTNGPIPALGSSDAMAHDRGVDMRRATTNNPFIDMMERFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUE8</accession>
    <name>A0ABR3YUE8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000141">
        <property type="protein sequence ID" value="KAL1892014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045596140" evidence="1">
        <location>
            <begin position="19"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="213" mass="23925" checksum="F71E0FDA171E1697" modified="2025-10-08" version="1">MHFLSTLALALSALGVQAGTVLQDHGYSITRTNGGNYMVFSSRYDDRMTPVSTITVDSQYKIASISALFNHLEVADENNMSLSAIFDVICDLEQTLPKWTNFVVFDKVDVPTSKLANDYRRSHDIEPFETFEVVSGSEGWKSFLETPYYKSLQELMPEKAGDVKKIIFKSVQDGGYWAKNPKMVTRMFFSFLANSGPYDDPEVALAEVNGWGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVF8</accession>
    <name>A0ABR3YVF8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">High-affinity Zn(2+) transporter zrt1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ZRT1</name>
        <name evidence="6" type="ORF">Cpir12675_004729</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000140">
        <property type="protein sequence ID" value="KAL1892040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF44">
        <property type="entry name" value="PROTEIN ZNTC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="285"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="450"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1892040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="470" mass="49889" checksum="700442220975C0FD" modified="2025-10-08" version="1">MSGSEEVEVAFVNAPSTTTAAAATTAPPTSTTATEAPVTAVSECHTHGSQFHCMAGTVEYLVGVPVTKATSLPTKYDGCHSHGSELFCVDENGNDVSLTREDSEALSSTSTTSTTSKADMDCHFHAGVEHCVPKDGSAIAVSCERVDRDYDVKLRVGLLFVILATSAIGVFGPIFLTSILPNKLGFVFVVLKQFGTGVIISTALVHLLTHAMLMFENECLGRLEYESTATAIVMAGVFVSFLTEYLGHRYVNWKQSKNKANSVQNALEIALSNEMVNIVVMEAGIVFHSLLIGLTLVVTGDSAFMTLFIVIIFHQMFEGIALGSRIATLGTGKTSALAGLGHHHTGEHSHDKSAVQVIDSPAHSVTEAPRVSMVKKLLLASTFALVTPIGMAIGIGVLDHFNGNDKETIIAIGTLDAFSAGILLWVGLVEMWAVDWIHGEFANSSPIKTAIGMLGLISGMVLMSFLGKWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWC1</accession>
    <name>A0ABR3YWC1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Autophagy-related protein 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ATG11</name>
        <name evidence="12" type="ORF">Cpir12675_004457</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Preautophagosomal structure membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Vacuole membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
        </subcellularLocation>
        <text evidence="7">During pexophagy, accumulates in the vacuolar membrane region, where the peroxisomes contact the vacuole.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ATG11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000126">
        <property type="protein sequence ID" value="KAL1892689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040040">
        <property type="entry name" value="ATG11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019460">
        <property type="entry name" value="Atg11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045326">
        <property type="entry name" value="ATG17-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13222">
        <property type="entry name" value="RB1-INDUCIBLE COILED-COIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13222:SF1">
        <property type="entry name" value="RB1-INDUCIBLE COILED-COIL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10377">
        <property type="entry name" value="ATG11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04108">
        <property type="entry name" value="ATG17_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0072">Autophagy</keyword>
    <keyword evidence="6 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <keyword evidence="7" id="KW-0926">Vacuole</keyword>
    <feature type="domain" description="Autophagy protein ATG17-like" evidence="10">
        <location>
            <begin position="106"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="Autophagy-related protein 11 C-terminal" evidence="11">
        <location>
            <begin position="1089"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="589"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1261"/>
            <end position="1306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1360"/>
            <end position="1414"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="544"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="615"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="753"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="830"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1261"/>
            <end position="1271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF10377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1892689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1414" mass="159305" checksum="F131B9CF451B018C" modified="2025-10-08" version="1">MSTLDVFIAHSGLKLVADTSRFVSIDDFKSWVSHATSLPTSNLVALTRTGRSAKTQSLHLETEFFIYDTRVSSTKTPNISPLISQAPLPNAFKVFEPPNSIQDIKSIASWKELYRKRQEWALKITADCERLDSLAFDRFREIDVTVQCIDVALMNLDISIKPLQSRYEELKKWSPGALKENEMLATEREKHLKIARSVPTLPEMVSFMTAKQIQQNAKTTLEDLLEPEISQRVGRSAMKALERLKSYIEAVDNDALNMTDRFRELSASFESLLSRSILTRSDESRGILEAVQSISKKIDTDYQTILPLSGSPKDLAQISRTALTHTDKLLPTLVKRATEMSDLLLYVTENRNAIAIECGVFMRTITEVVSLLQRLKNSMARLGETEDDMAKFDYLRLIHQLPYMYSSFIAEAVRRREWKDKITTDSANLANTMAMFQDEETKRRRKWAKMVGSTYRADKVDSPAMGMEVNLQGGHENWPELTKRDLEAFITVFGDNGGDPAILEDIQKLLGDLNAPTRQQVKRIKAFKNGSLHETSMGFSGLLIRGDEDLIRSLQDDKVRLESKAMTAESRIKRLEDLLHRQNQARSQPFSSLDLYNKGSPRLGSRRLSTTEHADSALVVQLEQLKEELASEREKTELQQKTMAALNNETEVLRKQSEDSNSTKKDLFDNLEALKREFNEERRSLLSEANMLREKLEETEDYMENFGMSRENEKATYDERVNSLSDDLEKERKGRHDEKLKYNGQIEYLRTETRLQRETMDTMQKQIQTLQEENKGLAKKLSVEMSTTELQNRVLDDLYRELLPGAELPTDRCDLTDNLLSKAFEIIGIIKTIENDISVLQSELDQTQCTNKQLRASVAESSKKLVDMEAASDQLRESLAEEKAKSEATEAELEQGRQEIRELRVRISDGETGSESLQRKLEEDEKKLRLLKEELARRQSQVGRLEEELRCLREKFGVSQAKYDSLDSLFQIRTEKAKDLTKRIYTQNDRLVRLLERLGFIVTREGATMSVQRIARSERSTAQLVNPNESLATPSLVRQASTVTTRSGLEGEDLDQIYWMNNSDANVESEKYSAFINSLGGFDMETFTETVYRRLKDMEHLARKFQRDARAYRDKAHVMQKEAHEKIAFKNFKEGDLALFLPTRNQTSGAWAAFNVGFPHYFLREQDSHRLRTREWIVARITRVQERVVDLSRSLQNANGDADSVTTNEENDNPFQLSDGLHWYLIDAHEDKPGAPSTPGLGKSTVAGSKVSAVADLHIHTTKSSKDKRRSINNGIEGVSKTLSRNLESRRSSNSSRKAFPLIGSGSGSAGGGTGLLKGSALASETNSIKDATSPGVMSPRVLSPVVAMSSISGAIATATNNDEAGSGGMAEGARKSENTALGSSPSALVDGATASSRRGTRGVRDVIDSLMGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWC6</accession>
    <name>A0ABR3YWC6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Centromere protein H C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_004456</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
            <location evidence="2">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the CENP-H/MCM16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000126">
        <property type="protein sequence ID" value="KAL1892688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040034">
        <property type="entry name" value="CENP-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008426">
        <property type="entry name" value="CENP-H_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48122">
        <property type="entry name" value="CENTROMERE PROTEIN H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48122:SF1">
        <property type="entry name" value="CENTROMERE PROTEIN H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05837">
        <property type="entry name" value="CENP-H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0137">Centromere</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Centromere protein H C-terminal" evidence="8">
        <location>
            <begin position="19"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1892688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="233" mass="25931" checksum="3BE402973F265FC0" modified="2025-10-08" version="1">MDIIVPPDEPLQLLTDEKKVLKLYDQLERLRLEIAIIKAQQAHAQSSSSSKFSAGTSVEEVREYKEKLLKAKSRYVVQKEVVDSILMMYPILKAVHQGTFCSPIERDLTPYLIDRDAASVVVSKKSTGIQSALEKAVIVQGKVLKAWSENVGLASDVHKLAHEIGQQKEDPLNVADGDNELDQLNTELKISRQKWSVMKGTASAVVAGSGIDWARDPELMEIVLDPEDMDLHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWK4</accession>
    <name>A0ABR3YWK4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein argonaute</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ago1</name>
        <name evidence="4" type="ORF">Cpir12675_004528</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the argonaute family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000130">
        <property type="protein sequence ID" value="KAL1892445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02846">
        <property type="entry name" value="PAZ_argonaute_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04657">
        <property type="entry name" value="Piwi_ago-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.10">
        <property type="entry name" value="paz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014811">
        <property type="entry name" value="ArgoL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032472">
        <property type="entry name" value="ArgoL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032474">
        <property type="entry name" value="Argonaute_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036085">
        <property type="entry name" value="PAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003165">
        <property type="entry name" value="Piwi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045246">
        <property type="entry name" value="Piwi_ago-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22891">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08699">
        <property type="entry name" value="ArgoL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16488">
        <property type="entry name" value="ArgoL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16486">
        <property type="entry name" value="ArgoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02170">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02171">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01163">
        <property type="entry name" value="DUF1785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00949">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00950">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101690">
        <property type="entry name" value="PAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50821">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50822">
        <property type="entry name" value="PIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAZ" evidence="2">
        <location>
            <begin position="291"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="Piwi" evidence="3">
        <location>
            <begin position="551"/>
            <end position="847"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="898" mass="101004" checksum="D03DD5C974F0CF9A" modified="2025-10-08" version="1">MNTTVSPRPSGARGNTRIDLPAEAYLDPSSSIVYPRRPGYNSVGAEINIEINQFRIMNFDKSKKVWQYDVSAKFLGQREPRNIDILIAKAWKMPECMAVLENHGPKWLYDGRKLAWSSTKVNDLTFVVDLDSGRLNNKGENKLELKLRPTTAIDLSLISAYVLQKSDMNSGVLEGINFLDHLIRQYPSEINIAIRRNFYRPNAQLEPLAPYVNCAKGTYASVRLNHSAINGGIGLGINVDVANTAFWASNGTLIDLASAYLPTQIRLNTSIAAALKPVKGPNGIAMSQAFKALRRIQKIRFWCPHQKSEGLTCEHTLFGFAASPKYGTEGVTAKTYKFSFDGREVSIVEYLRARYGLTLKYPDWPLVETTKRGTYFPPELCVVSPMQRYPYKLDPEMTAKMIKCAVTRPDVRKKAILQGRDALRWGQDPYMKHFGLNIDNGFTKTKAKLLKNPILSYGTGPINPKVAGRWDLRNVKFIKPNTRPLRVWGVFCDDGRDKPGAEQFARTFRQVFTSHGGIVASNAVIRARQGDGCFKAFHDGLRQQSGAHPDLIFIIVRGKGSSLYERYKKIGDCTLGVITQVVQSSHVAKNQPQYHSNVCMKVNAKLGGISCHVPDGPNISKSSKGPTIIIGADVSHAPVGMAVPSLASMTMSYDRHCTRYGAAVETNGFRKEIVTRDNIHGLLSRLYQHLSLPQPLKHVYYLRDGVSEGQFQHVIDEEVAQMKQFFRKQGLDPLFTVIIATKRHHIRFFPERGDRNNNPLPGTLVERDITHPFQFNFYLCSHAAIQGTARPVHYHVIMDEAKCSPNDLQQMLYSQCYQYIRSTTPVSLHPAVYYAHLASNRARAHEKTSEMRMGDMASELQQELIINGGRGEDTTALKLETLGYRPENTFFRSTMWYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXG2</accession>
    <name>A0ABR3YXG2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Apc15p protein-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000124">
        <property type="protein sequence ID" value="KAL1892727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008402">
        <property type="entry name" value="APC_su15/mnd2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05841">
        <property type="entry name" value="Apc15p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="409" mass="45409" checksum="032EE8FB4ED11C22" modified="2025-10-08" version="1">METYFSQSGISSHNAYMLWSVSSQHQESQYSTFLDNAADASETQNRSGDISASQQSHIRRLNQTIIENSHLGRIASEEKLIVRRRHAIADFGSTWLKPPAINKTLSQLREERREQEEHAEALRREQLQQELADAEAAAEGRMEADEMDEDQEVGEAPADLDDEIPDADAEDSAFQFSEIDEDDEDDEDDEDDTSGEESEDGSSSGDGDRESSDASASDDGARTPTAATPDQTAREQRHSDLLAARMREDAMRRAMLQRGAETEPADDFYGDGTSFAVDQYEDHETSQGEVLDEEDFGNGEMGMERDLDEEVPEAEMSGLYEHTDSDESLSSSEEEEDSEEDDDNGYDDDGDDQFSRFARRTIAPPVSPTLGSRGGRGLHRAGVSDFLAPHQESSILESSPPMRRAARQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXH9</accession>
    <name>A0ABR3YXH9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Purine nucleoside permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004286</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000117">
        <property type="protein sequence ID" value="KAL1893095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009486">
        <property type="entry name" value="Pur_nuclsid_perm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38643">
        <property type="entry name" value="PURINE NUCLEOSIDE PERMEASE C285.05-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38643:SF1">
        <property type="entry name" value="PURINE NUCLEOSIDE PERMEASE C285.05-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06516">
        <property type="entry name" value="NUP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045241667" description="Purine nucleoside permease" evidence="2">
        <location>
            <begin position="25"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="462" mass="49360" checksum="B553BB6F5C497774" modified="2025-10-08" version="1">MHPGFMKHALLLTSAVFLSVPVSGANVVRNQTTKTGFSDSRAGRSRHAQSTASGARVPVSQATDSCSNGTYAHALAEPKIAPKVLIFSLFPSEADIWYQRWNDSGFDNLNAVQTSAPGLCMLYPHVHCTPDHSVCQVTTGMGEINAAATAMALGLSPKFDLTSTYFLISGIAGVNPLRGTLGSVGLAKYAVQVALQYEIDSREIPSDWAMGYVAYGTKKPLQYPSILYGTEVFELNEALRDAAFLMASNATLADSEAAGLYRAKYSNMGDVTQAATSSPAVVKCDTATSDVYYSGKMLSEGFEKVSEVWTNGSAQYCMTASEDNAILEVLMRLAIEGLVDFGRVMVMRSGSNFDRPPDGIAAYEHLLALDQNGFSIAINNLFNAGIRIVQGIVKNWNCTYEKGLSPSNYIGDIWGSLGGQPSFGPGSITGGYPIKAGGQTGNLMRRGMTGADFAKGHSMMQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXU0</accession>
    <name>A0ABR3YXU0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Acetyl-CoA C-acyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_004652</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA</text>
            <dbReference type="Rhea" id="RHEA:21564"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="2.3.1.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000137">
        <property type="protein sequence ID" value="KAL1892144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050215">
        <property type="entry name" value="Thiolase-like_sf_Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853">
        <property type="entry name" value="3-KETOACYL-COA THIOLASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853:SF5">
        <property type="entry name" value="ACETYL-COA C-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0630">Potassium</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="9">
        <location>
            <begin position="14"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="10">
        <location>
            <begin position="298"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1892144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="422" mass="43101" checksum="3EA19D2E6C593A87" modified="2025-10-08" version="1">MALRALTAKTPTDVVVLSALRTPITRAGRGPLKDAYPEELLAAVLARTVSSHANLPPSAIADVAVGTVLSELGGSKAARAALNSIRSISPHATSLYTVNRACASSLQSIAAIAGAIQTGSIDTGIAAGMESMSRNYGSRAIPTAYWPALADAAVAGKDATDCFMPMGLTSENVAVRYGIDRASQDALAFESHRRAAAAQAAGHFTREIVPVTTRFTPLPPKNGTASEADLAERTVTANADDGVRPQTTRESLAKLKPVFTAGGTSTAGNSSQVSDGAAALLLMRRSTATELGLSSAIMGKFGGAVCVGCAPSEMGVGPVHAVPALLNRLGLRTTDVDRWEINEAFASQAVYSIRALGLEEAYAQGKVNPDGGAIALGHPLGATGARLAVTALHGLERTGGHVSVVSMCVGTGMGMAGVFVRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXU4</accession>
    <name>A0ABR3YXU4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">STE20</name>
        <name evidence="15" type="ORF">Cpir12675_004230</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000115">
        <property type="protein sequence ID" value="KAL1893211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01093">
        <property type="entry name" value="CRIB_PAK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06614">
        <property type="entry name" value="STKc_PAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.810.10">
        <property type="entry name" value="CRIB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000095">
        <property type="entry name" value="CRIB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036936">
        <property type="entry name" value="CRIB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051931">
        <property type="entry name" value="PAK3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033923">
        <property type="entry name" value="PAK_BD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832:SF22">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE SAMKA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00786">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00285">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50108">
        <property type="entry name" value="CRIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0589">Pheromone response</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CRIB" evidence="14">
        <location>
            <begin position="371"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="781"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="62"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="217"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="447"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="642"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="78"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="109"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="145"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="184"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="248"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="333"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="453"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="470"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="510"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="520"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="599"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="642"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="683"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="810"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1893211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1062" mass="116146" checksum="CE4DFE8D333CAB4C" modified="2025-10-08" version="1">MDPPPQTSSTSSTPISSRRRFSTRGLSKVNRAAHTRSSSTIADVTSGFGFGFDTSYLRSKLSSHSLRRAPSAPGVRRSAYSNASNASSQSQLPTSASGSFPFLHRDRSVPTSNSPNLSSPSPSASDRDYSAPSSAVLCIGPDSPPTSTTIKSSEDLVTSSAEAPSIPSPQAISTTDSVRQSVHQSPQQLKLQPQPPQLQHQASFAIRANALAALPEAVSPPTSPLDPLPSSKIGLPLPPTHQDIAAETEAKTTPEARHPSPPPPPPPQPETKPLPLPKSEPQSPVINPTPPPQLAKASKHLSISQLRASAVPRLSRKMSERKNSDGPTVATKRLSDEAKENGSGRPSVMRMRSGLSGFVNGLVGNTKKPLISAPENPVHVTHVGYDSNSGQFTGLPKEWQRLINESGISEKERQANPQTIVEILTFYKETTEKPTEDQVLEKFHHAGSQNHVSSPNASSPISPASLQSSGPMSPTSYQPTGMSHPSNTSSPPMSPRFPTVNNEGSFENPRSPPPVPTTPGGPRSMPPSSSAPKNYNPNLIPSRPAPKPPSAHANGQVRSHIQTKDSAIAMSPQSEPSSPPFVPAKDATMLPEEHRSRSNSRSTPQSAYSHHTSVQSSQAQAVAIQQQLLQQQQEQALAQAQAAMSRQVSRSSSKRAPSSISRNPSLMRKREHMPPHTPQKIRQSAQQQQPYPAQNYHYQQQQQQQQQQQQQHHHQQQIALQQQRHYEQQQMQLQQQQQQQQQHPSQVPNARPRNRQRASNNAEVLASLERICSKGDPRTVYRNFHKIGQGASGGVYSGHERGTNRLVAIKQMNLEQQPKKDLIINEIVVMKGSSHPNIVNFIDSYLCAGELWVVMEYMEGGSLTDVVTFNIMSDGMIASICHETLQGLQHLHSKGVIHRDIKSDNILLSMDGNIKLTDFGFCATINENQNKRTTMVGTPYWMAPEVVTRKEYGFKVDIWSLGIMAIEMIEGEPPYLTESPLRALWLIATTGTPKIKDEEKLSPAFRDFLQYALQVDPERRASAQQLLAHPFMKQCVPLKHLAPLVKVSREARALEKARKGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYD8</accession>
    <name>A0ABR3YYD8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein-tyrosine-phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_004340</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000120">
        <property type="protein sequence ID" value="KAL1892931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050348">
        <property type="entry name" value="Protein-Tyr_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000242">
        <property type="entry name" value="PTP_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134">
        <property type="entry name" value="RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134:SF449">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00102">
        <property type="entry name" value="Y_phosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00700">
        <property type="entry name" value="PRTYPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00194">
        <property type="entry name" value="PTPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50055">
        <property type="entry name" value="TYR_PHOSPHATASE_PTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="3">
        <location>
            <begin position="701"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="4">
        <location>
            <begin position="873"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="83"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="146"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="494"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="594"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="648"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="83"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="494"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="660"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1892931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1009" mass="109812" checksum="E43CAC51EF8C6400" modified="2025-10-08" version="1">MNRFPMHRRRRHRTVSPLEKNHVTSSPPTSPSPASNPDLIAVSASAPVPTKPKQPLHRLRTLKSALSGSASAINAAITLSSSLPPNLSAGKNSGQSQGTRVAKSTSARPQKETTAAATVPVTTAATEDVVKQNLKHRYRYRYRRRHKHEKLQPQQQQEQQEQQQQQQQQPHANNKPPGPTKKASVLKKTDPTTATATTFIATATGEAAETTVAAAATTPCQPPLDTINFTAPSRRQKRRHRWARHKDKKSITTALITQATTTPALTSSSPPQIAAVPLQPSLLFSSSSSLAFQPQAENIINKNEATASSANPMQIQLQQMPRATFETIQPVSSTLAITTKTTSPQSAVVFAAATAIATANPTSTSPSISTIATRPNISAAPFIPLRSKPIRADRIPVAFRNLQIHCPMKRARSPAPPPISTGAALHNPSIDAIAVAAPPSAGATSAVADFPLLATSSSSNIISQSNSGQNTHNSNVRAGLGSGLSIVATGTTSNAGTVPSLNTPRRSSFSGSVRMEKNKKGNASAAQKSKLQSPAIRTKPPAFSNSFFWGHGSSAAKNADASSMALSSSHQQWTSSSRVLSPLSVTSMMNSSSASATAAANRRSNDIRTPSPKGVKMPLFMSSSTQDIKAKFNELTWIERNRIAFGSRRPRTDNCTSSLARPATASASISSPSESRNGNNPFSPSRRLSFRYPEHAQPDLDRYPDILPWKHNRIVLNVPKGTQNYINASPITLISPNDSANLPDLRYIAMQGPTLASTPYVWRMISEQIQKQVVIVQLTNLVESRRSKCFPYLPLEEGSVMHLNDKDIWNDGWRASIRFVSRRVLADGAIESTKLVLRVEYTDNSKKPREWTVRHLFYTRWPDYGVPTAEDLPAFLQIIELSQHYSKDTRDPRIVHCSAGVGRTGTFIALEFLKRELDMGFLTGDGVSLVGGSMAPPPLPEEMSPVTPGGVDTRNDLIFSTVDWMREQRKTMVQSESQYMFLYQMLRKLWRDRYGLSAEDVAELAARGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ40</accession>
    <name>A0ABR3YZ40_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_004012</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000105">
        <property type="protein sequence ID" value="KAL1893665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="84"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="46"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="651" mass="71684" checksum="9BBA40ED8C22B496" modified="2025-10-08" version="1">MVSLKSHPDESTPQAISITSAMAGTSMNTNANAHVIADNHATSTHANADANSGINSGADASADAGTASELPRPGSPPQTKARKACLNCRRQKMKCRIDNGESCRRCSKAGVPCVFVPRANASYLRDLIVSSDSRDSDQVSFNRSVESRLKRIEDYLGLADGLPPPSPPSVQASEVNASADAPSSPDSDVFSALWPAVLALKKACTVNVSARIWDRSVIKALWRTFHDAMPGLHFLPSKQTFSSPRPLLLAGMLYCSSVRGSEEAAALSADYLSVLCCAIAQLCVPNSEISTLPPDLREREEWAFQTILGLILAGLLREAINAETGLWISLAYRLLLDHCPSESNITVRGHEWRCLFSGLQIVDLEHASLALACPVVPMTAPFPRLQVPLHDQLYRLSRMMHTGLTHFTGRGLPTVWSVFSQDTVNSMASSTPLPLQLQQMSRPSQNAQVPFTAVDAAVIRDWARQLEDWLVEFSDRAYESEHEKKLVFRQYVLHRLFVLSIYHPAQGCNLFANEITPNEQHELLVSARAAVRLHVYDSSIWSNWDLIVITWAALIVLQGVEGGMGEATDIEHVSVHLKNLTNTNELKPSIRELLALNLQQRMRNMHSPVDLISQSGPVEIAEDASNWYIFNEASLQAGYELWQYDQGGEFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZF2</accession>
    <name>A0ABR3YZF2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ERAD-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">HRD3</name>
        <name evidence="5" type="ORF">Cpir12675_004244</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000116">
        <property type="protein sequence ID" value="KAL1893098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF147">
        <property type="entry name" value="SEL1L ADAPTOR SUBUNIT OF ERAD E3 UBIQUITIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047286658" evidence="4">
        <location>
            <begin position="21"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="770"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="799"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="804"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="824"/>
            <end position="842"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="859" mass="95664" checksum="71F7F71B978DEB18" modified="2025-10-08" version="1">MRYTPFWLVLLAQALGTVVASTDGHQAILNDNSQDSGHQNAAHHAATGATDNVPALDIIKGDRQQKSAPASQPGAEYVDQARTIFSALEKNPPTPNHWRSRGFFADLILGALPSFSLSAPQDRSASQHIQSIPPGLAKAVNLLERAAAESNPDAFHMLGDLYFYGNFTWPRNFDKAYAHYKNLAGLGDASGHFMVGLFYSSGISQLVPQDQAKAHLYYTAAAKLGHTRAQMAIGFRHHMGIATPKSCEKAGIYYRSVARKAIDWVNSGPPGGQHWVVEAYHISEEDGGIYGFGASATSSGANAVKVNPNSDANAAIDDVIEYLDLMSKKSDSKASLNLGRIYYEGQRGLERNFDLAKKYFLMVAHQYWKRDGTVIENPPSGLDRLAGKAATYLGRIYLRGEGVEPNFTKARYWIQRGIANGEPQAYYLQGLMYKHGLGVTQDSEIASDRFKYSAERLDYNPSQVEMGKIYLERGSEADVKSALHFFEHAALHNNLEAYYYLGELTYQGIGRDRACNLATHYFKRVAERVEPLTSAWSIANDAFEIGDIDTALVHYLVMAEQGWDAAQINMAYIIDSAKSWLKLPLATSPLPTPSENLQNHNLAMVYWTRSSMQGNVDATVKVGDYYYYGIGHEKDMIQAGNWYSLAAEHSASAQALWNLGYMHENGMGLKQDFHLAKRYYDMALEVSPEAFLPATVSLLRLRMRSAWNTMTHGPIHSIEYEPKTSQHKSIREWIKAFMADQPRYYEQYSENMFEETYHEEVAHEVYEESILDTMLLVSIIMLISALIYYRHQRQLEAQRRREANAQGQGQGQHPLNPNQQHAEPAPGAGHNPANNPPFAAGFMQPGGQFQNWGAGGVGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZL1</accession>
    <name>A0ABR3YZL1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Holocytochrome c-type synthase</fullName>
            <ecNumber evidence="10">4.4.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CYT2</name>
        <name evidence="11" type="ORF">Cpir12675_003949</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>holo-[cytochrome c] = apo-[cytochrome c] + heme b</text>
            <dbReference type="Rhea" id="RHEA:22648"/>
            <dbReference type="Rhea" id="RHEA-COMP:10725"/>
            <dbReference type="Rhea" id="RHEA-COMP:10726"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="ChEBI" id="CHEBI:83739"/>
            <dbReference type="EC" id="4.4.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the cytochrome c-type heme lyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.17" evidence="10"/>
    <dbReference type="EMBL" id="JAWDJO010000102">
        <property type="protein sequence ID" value="KAL1893830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004408">
        <property type="term" value="F:holocytochrome-c synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000511">
        <property type="entry name" value="Holocyt_c/c1_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12743">
        <property type="entry name" value="CYTOCHROME C1 HEME LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12743:SF0">
        <property type="entry name" value="HOLOCYTOCHROME C-TYPE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01265">
        <property type="entry name" value="Cyto_heme_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00821">
        <property type="entry name" value="CYTO_HEME_LYASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00822">
        <property type="entry name" value="CYTO_HEME_LYASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0349">Heme</keyword>
    <keyword evidence="6 10" id="KW-0408">Iron</keyword>
    <keyword evidence="9 10 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1893830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="310" mass="33569" checksum="912218CFB2B445EF" modified="2025-10-08" version="1">MAGTSEICPVDHKAMAAAKSTSATCPAPASTVETLPASGSADACPVDHHAREAWLKQARAASAAAADAASATPYPIPTTPAATTPATAHSWPSTLWSYVPFISGPSTTSPDTTARQTSKPAQSHLGLGLDREISTIPRASMPFTDNVAQPSNHEIESGADPVSGNWIYPSEKMFFDAMKRKGHDARAADMRAVVPIHNAVNERAWQEIKEWEKPYLAGTACEVPRLHSFSGLSTKLTPKARWNTLLGYQAPFDRHDWVVDRCGQTIEYVIDFYPGRPKPSGQLSFYLDVRPKLNSWEGVKMRILRCAGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z049</accession>
    <name>A0ABR3Z049_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glycerophosphodiester phosphodiesterase</fullName>
            <ecNumber evidence="2">3.1.4.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_003985</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a sn-glycero-3-phosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12969"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:83408"/>
            <dbReference type="EC" id="3.1.4.46"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycerophosphoryl diester phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.46" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000104">
        <property type="protein sequence ID" value="KAL1893687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43620:SF7">
        <property type="entry name" value="GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE GDPD5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43620">
        <property type="entry name" value="GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046734967" description="glycerophosphodiester phosphodiesterase" evidence="7">
        <location>
            <begin position="21"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="GP-PDE" evidence="8">
        <location>
            <begin position="76"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="415" mass="46174" checksum="0C98C07742FF68B7" modified="2025-10-08" version="1">MKSTTAAILIAAVGSSSASALPAVERRSFIDLEVNPVTNVQVGIRPYWLVDEMDKSATKEALQQCVKDVTDFGVSQWSIGHRGGGTLQIPEHSWESNLAGARMGAGILECDVAFTKDLELVCRHSHCDLHSTTNIVAIPELNAKCQVPFISSDGMNPAQAKCCTQDITLKEFESLCALMEGVNEHATTPEEYIRGTPDWRTDLYTCGTMLSLKEHIELVEELELKHIPELKTPELPMPNGFTQEDFAAKMLKEYLDANVEPSDVFPQSFLYSDILYWKSKFPEFASNLVLLDDTDDMSEQEAIERLKKYAADKIPIVAPALNALVTNVDSTIVPSQYAKTAKSLGMDIIAWTIERSGRLSEDNDDYYYHPIHEIVDSDGEVFEVLRVLLEDIKVKGVFSDWAATTTFFENCMGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0B6</accession>
    <name>A0ABR3Z0B6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000107">
        <property type="protein sequence ID" value="KAL1893636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="59" mass="6369" checksum="8BD65904F5727B7A" modified="2025-10-08" version="1">MGRAPSGEAARFPDRLFFQGRSIQKRGKEVSSPDTSSGQSAFAGVRKVQKPFMTVKGPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0F1</accession>
    <name>A0ABR3Z0F1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Btz domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003803</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000096">
        <property type="protein sequence ID" value="KAL1894115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="454"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="602"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="727"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="136"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="199"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="249"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="613"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="641"/>
            <end position="657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="886" mass="95495" checksum="CE93AC1B42988CD1" modified="2025-10-08" version="1">MSSVSGHSSRRPRKFALRPPHKARSLNDDASVSDSVNSDDQIFASGSSDTTSNMDDAVSVSVSMSNHHKKDRASSVSACSQNSNSNPAVIAATTLTCSSASSSSSKQQSQQQSRPKPKQPKFAASTTAATLVKADASAPVTAPASTPTSVSTPVSTSASPSRCPKPRSPRAGQREQQQNPPPLIVSSALETAASGSRAQPQQPNQRHLQQQGPTIAKSRSSYNSSHSSSSGHPTGSSFFMPNSRYPYSNGNNNNNNNNNNNGPSHSSGRAISYHSSYNSRGNSRPQYDNTSPAGSYSSHQRMSYHNSATAAPLPRLYRNTNIDTTPAQWTHDKHFETSYYPYGYVASLNPKSHANNRQPESGLKRQPESQQRIDRSLSSEKHIGNVRMRVIIPGMDSPKLYDGFRLKQYTKLPDHRPPLRRDKPVQVRIPGDHMRLVLPANDRSFDFIPRALRPNQQKSRANRQRSQYGSMSTYSRAPSIYGGASSLYSASIVPSLAPSRRSSIVDVMFSPAAPIVSRPVLPIVDSARPKVKLPLPAQSISPYGQAQARSNTRMVQEQELIQTSIQTSVPTQAPAHHQNQHNVPSALLAAQEKPYSVTSATTLPSLAQPSNDPPTATSTRASSAPAKQLADSERSSHPSKTTTSGDAVVVSSSASHALPTTQPPLEIISMPACSTNNNTAFQDQIPSLPLLNQAPYTNQQPAMATSNTSMPQIPERAIHAPVFQPGGVHPTTPSVHPGMQQQTPQPPPSQPYYSGPGQYCPVPPYNSNPHEYQYMPPHSTRIVPGAGPGHMGMPQHQHQHGYEGPMQANLSTISRQINGMTYYFTSSQATPAPVPVGPSHAQSQSQIPIQGMYGDNGGDYYQNGGGSEAGSGYYIYPQLQPVYYPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0M5</accession>
    <name>A0ABR3Z0M5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000101">
        <property type="protein sequence ID" value="KAL1893852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF10">
        <property type="entry name" value="ABC TRANSMEMBRANE TYPE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="43"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="75"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="467" mass="51950" checksum="C4A166C3B43CB437" modified="2025-10-08" version="1">MSAPTPTTNPVPAAATAEESTPASVPVPAESSASEISTKTANPAPEAAAAAPAATEAPGPAPAATSETPAAGASDKADGDVPKADADATAAQAAAQAAYDADTLYLEEHMPERLDMSTTAYGMASVNQGHVPLDIDNDAFSEGNEGSIIDSTYGSEGDSTNTASISSSIFHYQYENGRRYHAFREGQYMLPNDDREQERLNLQHHIWRLMQHGGLYTAPIKEEPGMRILDLGCGTGIWAIEMADEFSQAEVYGIDLSPIQPDWVPPNCHFHVDDYEDEWTWREDEKFDYIHGRALGGTCADWTIFYQKIKNNLKPGAWCEIQEYDAWVFSDDDSCDRARWTMDWVDKLDIASRKFGRTMNVARFHKQWMIDAGFEDVHEEIVRIPIGPWPKDPHLKELGRFEQIHMQMSVESHTLALFTRIWGYTEEQARLLIEGVKRDFRNKDLHLITSYRFISGRAPMNPSTVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z197</accession>
    <name>A0ABR3Z197_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Hsp90 cochaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">STI1</name>
        <name evidence="8" type="ORF">Cpir12675_003846</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000098">
        <property type="protein sequence ID" value="KAL1894062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041243">
        <property type="entry name" value="STI1/HOP_DP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006636">
        <property type="entry name" value="STI1_HS-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904:SF523">
        <property type="entry name" value="STRESS-INDUCED-PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904">
        <property type="entry name" value="TPR REPEAT CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17830">
        <property type="entry name" value="STI1-HOP_DP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00727">
        <property type="entry name" value="STI1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="4"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="STI1" evidence="7">
        <location>
            <begin position="137"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="327"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="STI1" evidence="7">
        <location>
            <begin position="527"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="196"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="217"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="232"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="244"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1894062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="579" mass="63847" checksum="8B28D1571101085F" modified="2025-10-08" version="1">MSSIDELKTLGNKAIAAKDFDEAIAKFTEAIAIDSSNHILYSNRSAAYASKKDWTNALNDATKTTELKPDWAKGWGRKGAALHGKGDLVGANDSYEAGLKVDPNNAQLKSGLESVTKAMQAEVGGSPVPGLGQMFSDPNLIAKLAANPKTSSYLSDPSFMAKIQQLQRNPEGSPDLFSDPRMIQVLGVAMGVEMDVRDSPPEGADIVDMPVSDAPPISKPTPAPKKAPEPAPEPEPEELDEEQLEKKKAKEAADKEKMTGTQHYKNRNFDAAIAHYTKAWELHKDITYLNNLGAANFEKGDYEACVEACSKAVEEGRQMFADFKVIAKSYARIGLAYEKMGSMQEAIDNYNKSLMEHRTPDTVNKLRAAEKKIVEDARLAYIDPAKAEEARLDGNAKFKEADWPGAVAAYTEMVKRDPEDPRGYSNRAAAFSKLLELPSAIDDCNMAIKKDPKFIRAYIRKAQTLFTMREYSKSVDACEQAMEVDIEHHSGANAREIEAQMQKAYSAMYSARDDETEAQTRERIMRDPDIMSIMQDPVMNAILQQAQGDPAALQEHMRNPSVRTKIQKLMAAGVIRVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z372</accession>
    <name>A0ABR3Z372_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003636</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I LYR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000089">
        <property type="protein sequence ID" value="KAL1894510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20265">
        <property type="entry name" value="Complex1_LYR_ETFRF1_LYRM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045296">
        <property type="entry name" value="Complex1_LYR_ETFRF1_LYRM5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052000">
        <property type="entry name" value="ETFRF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21024:SF0">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN REGULATORY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21024">
        <property type="entry name" value="GROWTH HORMONE-INDUCIBLE SOLUBLE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13233">
        <property type="entry name" value="Complex1_LYR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="87" mass="10633" checksum="4302ADD5DB329F5C" modified="2025-10-08" version="1">MKRVNLELRWQVIQSYKELLFVGKEYPLGFAYFRKRLHKAYTANAHLQNEAEIRACLERAEFVKKEITTLYYLKKYRALRHTYEPFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3L5</accession>
    <name>A0ABR3Z3L5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_003528</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000085">
        <property type="protein sequence ID" value="KAL1894787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="240"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="327"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="382"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="415"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="479"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="507"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="89"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1894787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="640" mass="72126" checksum="05BAD9DE95518988" modified="2025-10-08" version="1">MSEMKGVNAAVAPVTASGVSADDRRAFAVLTHPDDSYTTDGVYWADLPFGKRVRFVTSVDAAEAAAELRSLGQMIKKDPLSPFSWYFDNAILPGAGLGLEGYVLFSIGNLAPLFKAVWPYCWGHSQPGVCSQNWIAAVTYLEIVGIMVGQMLVGVMGDWIGRRFGLIQDAVIMFIGLVMLTASWGMTLQGWIICYALCLMFYGIGVGGEYPVTATAAMENALVAGTMSTREDRLHRGRRVTMAFLMQGWGQFFNQLTLIVCLLIFNRHAGNPGNPPYSEMAAQVTFRLSFALPAIGTLWLVYYRIWKMPDASKQLELAKKKAKVTGYDLNALRFTFSHFGGRIFATAGTWFANDVFFYGNKLFQGAFIKVISSNPDSLLTQWWWSLINVAVSMVGYYLATFLIDNKLYGRKNMQQVGFFMCFLMFIIPAYNFEYYKRPENIHWFQVMYFLSSFFNQFGPNSVTFLVAGEVFPTQIRASAHGFSACLGKAGALLASVLYNYIDDQTKFYFVPWFGLAGMVLTWLFLPDTTGLDLQEQERRWGHILKGEENNYHGIAVHKQHLSMWERFRGVGNSYNPQLDHEEKINEYKAEWIAAEQERATTEDSSCSNDTCFSPEINNYMQRTYNISRSGDSIDEKKVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3V0</accession>
    <name>A0ABR3Z3V0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Autophagy-related protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Cpir12675_003328</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Preautophagosomal structure membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000076">
        <property type="protein sequence ID" value="KAL1895311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045269">
        <property type="entry name" value="Atg1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348:SF22">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="197"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="256"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="258"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1895311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="282" mass="32034" checksum="2DD28FF5EA791852" modified="2025-10-08" version="1">MTKTDINETVIRTIILQVVMGLVHIHDKGIVHRDIKPENIQFSVAPKVTYPVVIADFGHATFLRCGKMLTSMAGTTPFRAPEIHYHEPYDFAVDLWALGITILTMLMPNHLDTFGKLFSYSQEGVDSSLERVFKHCKIKIRRNGRSFIRACLRINAKERMASNEALKHSWINYKNHDMRVVYKRVMSRWRQCPPRVDMANNLPASQTPGAQPKNLAFPKNGSSHSKKSILKEEVQNVAANLPWSDTLPLSLREAVEKPNSTATTHEPTHCSSCEQSKSKSWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4U4</accession>
    <name>A0ABR3Z4U4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">precorrin-2 dehydrogenase</fullName>
            <ecNumber evidence="1">1.3.1.76</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MET1</name>
        <name evidence="11" type="ORF">Cpir12675_003297</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.76" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000075">
        <property type="protein sequence ID" value="KAL1895340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004851">
        <property type="term" value="F:uroporphyrin-III C-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11642">
        <property type="entry name" value="SUMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="entry name" value="Cobalt-precorrin-4 Transmethylase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="entry name" value="Methyltransferase, Cobalt-precorrin-4 Transmethylase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006366">
        <property type="entry name" value="CobA/CysG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012066">
        <property type="entry name" value="Met1_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050161">
        <property type="entry name" value="Siro_Cobalamin_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028281">
        <property type="entry name" value="Sirohaem_synthase_central"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45790">
        <property type="entry name" value="SIROHEME SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45790:SF6">
        <property type="entry name" value="UROPORPHYRINOGEN-III C-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13241">
        <property type="entry name" value="NAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14824">
        <property type="entry name" value="Sirohm_synth_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036555">
        <property type="entry name" value="SUMT_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75615">
        <property type="entry name" value="Siroheme synthase middle domains-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="Tetrapyrrole methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Siroheme synthase central" evidence="10">
        <location>
            <begin position="134"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Tetrapyrrole methylase" evidence="9">
        <location>
            <begin position="307"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="276"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1895340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="594" mass="64164" checksum="462B09ED355CC16A" modified="2025-10-08" version="1">MPLLTALQCTGHVHLVIGPTPLAASRCVQSLAVGASVVVIGPSPNPSAPLHFTLQKLVDEGRVRWIEEDFRDEFLFTLGREEVGKVADAVFVVRGPAKTENAHISALCRKHRIPINVVDAPDLCTLSLLSVYTDGPLQIGVTTNGNGCKLASRIRREIASSLPAGLGSACSRIGSIRRQLIQEQQKERLEEERQINGVDTKETTNLPTFAAQRDDEEAEETTDQRASFNRLVKEGSEAALKGRKLRWLSQVCEYWPLKRLSEASDAEIELVLSVPEAPDQQSRADGGQESAQKEPGLVSSSSPGRGKIILAGSGPGHPDLLTRSTFHAIQAADVILADKLVPAGVLALIPRRTPVTIARKFPGNADAAQAELHSIAIAAWAEGKTVLRLKQGDPYIYGRGGEEIMFFREHGAGNDVTVLPGITSALSAPLFAGIPATQRDVSDQVLICTGTGKKGVAPTPPEFVPTRTVIFLMALHRIKDLIQELTEHLPSELGDTTTPTRRALFPLSTPCAVIERATCPDQRVIRSTLKSVAQAIEAEGSRPPGLLVVGAACEVLNQKIEEKEPQQEQGKSWVVEDGFLRLDFGVQKDIEAMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z533</accession>
    <name>A0ABR3Z533_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TIM8</name>
        <name evidence="10" type="ORF">Cpir12675_003132</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Mitochondrion inner membrane</location>
            <topology evidence="1 8">Peripheral membrane protein</topology>
            <orientation evidence="1 8">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the small Tim family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000069">
        <property type="protein sequence ID" value="KAL1895741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0811">Translocation</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Tim10-like" evidence="9">
        <location>
            <begin position="24"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1895741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="90" mass="10487" checksum="60C31354E72818FF" modified="2025-10-08" version="1">MAAKIDNADLSKLNDKDKEELRHFLEGESQRSHIQTTTHTLTEMCWKKCISGPIKSQSLDRAEETCMTNCVQRFLDINFLTMKHLESMRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z552</accession>
    <name>A0ABR3Z552_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Endoribonuclease ysh1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">YSH1</name>
        <name evidence="12" type="ORF">Cpir12675_003253</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000074">
        <property type="protein sequence ID" value="KAL1895347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16292">
        <property type="entry name" value="CPSF3-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021718">
        <property type="entry name" value="CPSF73-100_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050698">
        <property type="entry name" value="MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11203">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11203:SF11">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10996">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11718">
        <property type="entry name" value="CPSF73-100_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16661">
        <property type="entry name" value="Lactamase_B_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01027">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01098">
        <property type="entry name" value="CPSF73-100_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="9">
        <location>
            <begin position="36"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-Casp" evidence="10">
        <location>
            <begin position="260"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term" evidence="11">
        <location>
            <begin position="525"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="666"/>
            <end position="692"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1895347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="817" mass="90862" checksum="7A5FD133C64E2383" modified="2025-10-08" version="1">MATKRKAGAMASGTDDPVDPSDELMFLCLGGGNEVGRSCHIIQYKGKTIMLDAGQHPAYDGLAALPFFDDFDLSTVDVLLISHFHVDHAASLPYVLAKTNFRGRVFMTHPTKAIYKWLIQDGVRVGGSSSSSQPVYTERDHLNTFSMIEAIDYHTTHNVSSIRITPYPAGHVLGAAMFLIEIAGLKIFFTGDYSREQDRHLVSAEVPRGIQIDVLITESTYGVSSHTPRMEREQALMKSITGILNRGGRVLMPVFALGRAQELLLILDEYWEKHTEFQKVPIYYASNLARKCMLVYQTYVGAMNDNIKRLFSERLAEAVASGDVTGRAGPWDFKYIRSLKNLDRFDDMGSCVMLASPGMLQNGVSRELLERWAPNEKNGVIITGYSVEGTMAKQIMQEPDQIQAVMSRNIGAARRDGEKAMIPRRCSVAEYSFAAHVDGNENREFIEEVAAPVVILVHGEVHNMMRLKSKLLSLNASKATKVKVFSPKNCEELRIPFKSDKIAKVVGKLAGIPPPDHIITADSDEARLITGVLVQNDFKLSLMAPDDLREYAGLNTTAITCKKRFTMGAAGPDLIKWVLESTFGAVDELPEMRALNKLNSIQKGDVEMADEEVPHVVAAYMVMGCIKLRYKSDREVELEWEGNMFNDSMADSIIVLLMMAETSPAAVKRSSTPHSHSHSDEEEPKAVGLPEKNPHAHVSSVERLDRIFMFLEAQFGADSVTPIKEPKVPAEMLENGDEEGLEKTEEQKEEIAKQKIYELERLHKLDIPVPGVLVTVDKMQAKVWLEHLDIESGNKVFADRVRAVVEKAVEVTAPLWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z586</accession>
    <name>A0ABR3Z586_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003238</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000073">
        <property type="protein sequence ID" value="KAL1895377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="267" mass="28794" checksum="FC41D9E5B2778113" modified="2025-10-08" version="1">MTVLALHRPLVPSPLNPDHKAIAFGPRRAHRKIVISRRSANISPTQHLQRRKASEAFNAHVIATSLAVSPAPQPPSFSSPFQSQSQPRPLRRTAAASSSRPKNAHSHTSSAHALEEELAAMTEPLASFDDPSDGSKASASESSYALKTRLVSSSAAAELLSSPLAALLHILPLPLVSLFVLRFPGSKNSYNPAVTKKDRDVVAEDTSFLQDAADLEECRAGEIAGAATGYLPLVLTMRRLMAALGFLCLYALMQFEPLIRRPTRSYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z702</accession>
    <name>A0ABR3Z702_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Homoserine kinase</fullName>
            <ecNumber evidence="3">2.7.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">THR1</name>
        <name evidence="17" type="ORF">Cpir12675_002825</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-homoserine + ATP = O-phospho-L-homoserine + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13985"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57590"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.39"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:13986"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GHMP kinase family. Homoserine kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.39" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000059">
        <property type="protein sequence ID" value="KAL1896421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004413">
        <property type="term" value="F:homoserine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="entry name" value="GHMP kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00384">
        <property type="entry name" value="Homoser_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000870">
        <property type="entry name" value="Homoserine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00191">
        <property type="entry name" value="thrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20861:SF1">
        <property type="entry name" value="HOMOSERINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20861">
        <property type="entry name" value="HOMOSERINE/4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000676">
        <property type="entry name" value="Homoser_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00958">
        <property type="entry name" value="HOMSERKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="GHMP Kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="11" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="12" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="7" id="KW-0791">Threonine biosynthesis</keyword>
    <keyword evidence="6 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP kinase N-terminal" evidence="15">
        <location>
            <begin position="75"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP kinase C-terminal" evidence="16">
        <location>
            <begin position="269"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1896421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="360" mass="38619" checksum="EDE53E83B10A9319" modified="2025-10-08" version="1">MAESFTIRAPCSSANIGPGFDVIGLSLSIYLEVIVTIDPAAQQQSPVDYPLNCRITYEGAGSDGGEPIPLNPADNLITRCALYVLRCHNQWEFPAGTHVHIKNPIPLGRGLGSSGAAVVAGVMLGKEAGKLDLDKNRLFDFCLMIERHPDNVGAALFGGFVGTYLMPLNPEDAQRIEVPLSEVLPEPAGGVNTRKTPPIPPNNIGHYIKFPWAPAIKAIAIIPDFVVATHDARAVLPPHYSRPDVTFNLQRIALLPVALGQSPPNPELIHLAMQDKIHQPYRQNLIPGLGDIVQSMSPATQPGFLGVCLSGAGPTILALATDNFEVIAEKIISILKANNPKPITCQWKILEPAEGCSVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z733</accession>
    <name>A0ABR3Z733_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_003017</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000065">
        <property type="protein sequence ID" value="KAL1895977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025638">
        <property type="entry name" value="DUF4336"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835:SF1">
        <property type="entry name" value="METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835">
        <property type="entry name" value="YALI0C07656P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14234">
        <property type="entry name" value="DUF4336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1895977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="289" mass="31676" checksum="248D4F4E2B3C492D" modified="2025-10-08" version="1">MSTLVPANPEAVTVFANPTPNILTLSVPFLRFGRIPIGGRATVARLLNGSLAVFSPIALTPAVRSAVNGLGGDVRYIIAPDIEHHLYLSAWKSAFPNAQLIGIDGLPKKRAAAAAAQANSPADSDSDPQITDIPFAAVFTATNKKTLSIDAPFDESFNYEYVDGHGNKELVFLHKADRALIQADLIFNLPATEQYSKAPEELAQKKSGILYKIFSSFTHTDPAHMTLPRVWQYYLTCKNRESYTESVRRIATWDFDTIIPCHGDVIKGNGKECFTSVMQWFLDSKSKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7I2</accession>
    <name>A0ABR3Z7I2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zinc metalloprotease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003061</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000067">
        <property type="protein sequence ID" value="KAL1895783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016:SF16">
        <property type="entry name" value="METALLOPROTEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G07610)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016">
        <property type="entry name" value="PRESEQUENCE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="2">
        <location>
            <begin position="64"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="3">
        <location>
            <begin position="204"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1023"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1032"/>
            <end position="1056"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1895783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1066" mass="120117" checksum="599FB7B678AA77F6" modified="2025-10-08" version="1">MTTSTSPEVKLPPQWKLVERFDIDYVKSSISLYRSERSGMSVIVNDRVGPKVHGEFVVATEIFDHSGAPHTLEHLIFLGSRSYPFKGLLDTLAGRAYSTTNAYTAVDRTVYTLETAGWQGFAQILPIYLEHVILPTITDEGCITEVWHINGEANDSGVVYSEMQALEFQSNELIDQAQRRLMYDKNIGYRYETGGMPEELRLLSNDRIRQFHRDMYQPRNLCLVICGTVDHSNMLQILDDFEKTIEKDIPSLQTPFKRPWVDSEQPQSFKESISTFVEFPEKDESTGEIDITWLGPSCNDTVAMVALNIVFSYLCGSSASIIENQLVEKEQLSSSCDMWTEDRLKTVISFRASGVTTGKLDETESRIFALLNSVVEKPLDMAYLHSRLHFEKRSSIYSTEEVVDALAEPIVLDFVYGARDGSTLKGLKSLNAYDEALAWSEEQWCQFIKKWLIDNKHVSIKAIPSAELVQKIKTEEKERIAKRKKDLGEEELKRLAKLVEDAQKKNNLPVPPEVVNKFPVPDTESIKLIKSDTARLGPARKLGLLKNNAQAKLDKLAKSVDDPNAPFFQFEQVPSNFVHIYMHFSTSNVPYELKPLLRLFRHNFFNTPIMRDGKKIDFEQVVNELENDTIRYSMKSAQSLSDPEGTRLSFAVETGKYSTAIRWIQAFMFESVFDKDRLLATLSKILADLPEQKRDGYSMTSEVSQAIHLKTDSAQHAGRLLVQKVYYRRLKKYLIAEPEKVIGWLETLRKAMFKWSTTRIMVIGDLAKIENSVGAWDVLTGLKRAGNEELVKIEPPHTTRSEEGINPGKFGAVIVPMPTLDNSYGYCTSAGFTEWTDPRLPAAYVAVSYLEAVEGPLWNAVRGKGLAYGCGFSRDIESGTSKFYVYRSPDVTKALMAAYAAIKNIANGTDPVTSFQMEGAISQLVHQWVGEQSTMTAAAINNFTLGVMQGLPDDWTQSMLAKVRAVSPEDMCRAMTEILMPLFEPGKSNIVITCNPNLTDTLNASLTKAGFATRVQTLDEFQDDYGLKALDPEDDEEEEEEDEDDEEDDDDEEDGSDWTVSGDDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8K2</accession>
    <name>A0ABR3Z8K2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">S1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_002619</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EIF1AD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000053">
        <property type="protein sequence ID" value="KAL1896898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039294">
        <property type="entry name" value="EIF1AD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001253">
        <property type="entry name" value="TIF_eIF-1A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21641:SF0">
        <property type="entry name" value="RNA-BINDING PROTEIN EIF1AD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21641">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00652">
        <property type="entry name" value="eIF1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1-like" evidence="4">
        <location>
            <begin position="25"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1896898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="137" mass="15800" checksum="88CEE0252F1A22B5" modified="2025-10-08" version="1">MAKKKNFTHNVRDDDVEAPRTLEDGQTIARVLKATSANAWECELPNKKNILVQLQSKLHNNVWVRRGGFVLIGLYPEAEVTSKIMGEIVNVVLDEKKWRKMPYWPKEFPLRTFVDDDNDEEESNMGKLPPSDSEDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z902</accession>
    <name>A0ABR3Z902_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_002733</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000056">
        <property type="protein sequence ID" value="KAL1896637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="29"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="267"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="274"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="296" mass="34106" checksum="C515E342D56C6E57" modified="2025-10-08" version="1">MSQLPPPIYPNPPNATFGKKIDTVPLHLCQQCRRRPLILGTCPACQSVHYCKDDCRRTNRPTHRIFCSSLALSLDPAVMLSAPTSGLAGRHDRPFLMLMGRTYLHNRPAIDVYALLIDMFRLARHDRTWPWNQPEHTLPVILQDPQHVAKEMDVFLDNAMLDRSGLLPDWWDAVHKAHCLRMGWDVRLNNHFSFLRQGSATNIAEYYGHPMVPLQLRILMEQFEGAPFSDDKACDYLKMLVERESGEATIQYRKSLSQRLLLEWGKSDEDGEESQDHNSKSERCGDNEYGVFRQFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9F2</accession>
    <name>A0ABR3Z9F2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Autophagy-related protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002659</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000054">
        <property type="protein sequence ID" value="KAL1896711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="321" mass="36243" checksum="10C840E35DC670D5" modified="2025-10-08" version="1">MGWLGSLFGSSSNKDDPLKNLDPKLREFLDRESPIKHQKAEAENEFASTKDDAARRRAESAAASADKSQPLAVPRESLFPDGRYAHLWKTYKPLSSIEDEGKTNNEKMADILDGYKTRKDSIGRAALENCAIQQEEWMQCLKNGSWDDRLMLCRTQVRKFERCYNMQNRFLRTLGYQADPSRGDEFNDAIQVHADALYARMLEHEEAVAAAAAAGEPEPNWKPVVPVVSAPYTSQTSPAVKTEEEQRQWDERLAATPEEERPFEKAAMEADFNVKANTAGRMSRLMEGEGKEVEARRKAGKASLTDHIWALFKSQPGDEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9H8</accession>
    <name>A0ABR3Z9H8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L34B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPL34B</name>
        <name evidence="4" type="ORF">Cpir12675_002425</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000047">
        <property type="protein sequence ID" value="KAL1897243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.370.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008195">
        <property type="entry name" value="Ribosomal_eL34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038562">
        <property type="entry name" value="Ribosomal_eL34_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10759">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01199">
        <property type="entry name" value="Ribosomal_L34e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01250">
        <property type="entry name" value="RIBOSOMALL34"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="116" mass="12888" checksum="4E9F660423146AA0" modified="2025-10-08" version="1">MPSHRVTYRRRNPYNTTSNLTRIVKTPGGKSRVLHIKKRGTAPKCGDCGNALAGIPALRPREYAQISKPNKNVSRAYGGSRCGGCVRDRVVRAFLIEEQKIVKKVLKEQAEGAKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9L9</accession>
    <name>A0ABR3Z9L9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_002524</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000050">
        <property type="protein sequence ID" value="KAL1896999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="409"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="307"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="409"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="533" mass="58384" checksum="4366EC285CE6CE95" modified="2025-10-08" version="1">MPSTSSAPGSIGNGPLNKSEFYLASALQPPVRNLFGRVVAEKDSLDLLSERDGVKYRRQRRMLGSVYSAAAMAKLRPSIKAVVEKAILRIKSVQQNSRNLKGDKEKLTAGSHTRSIQSQGIEALDIREWTHIIAIEALGASILSWSPGYLRDGTDHHTGEHGYLTWRRRSVFGLFPLATKAGQASKAAGRLWGRLWGITFPTPKGFRPFFPGVYRQVKRRINLLVPTNSNPKSKGDARQDLLFSLIQLHLEKPEFTDEYLRRMAVTNFGAGHETLAATLTAALALIAMESGVQQKVYEEMQLQQAEGSATSVDENTASANGKGGNARDKPMGYTYLQACIKESQRLFPVISMSMSRVVGPSGLCFSGYTFPPGTTIGCSPTAIHRSMQLFGPDSYSFRPERWLVPISSPTSAASSTTISPHSSASPYPDDCEPRAPTWTLASGLQVPAYCETESPADARLRIAALERNSLAWGAPGHTCPGRHLAELVVSETMAGLCRAFELQLDVSRDALEDSIRAYYLCVLFDVKVDFQPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB70</accession>
    <name>A0ABR3ZB70_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_002164</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000039">
        <property type="protein sequence ID" value="KAL1897819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044613">
        <property type="entry name" value="Nep1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46468">
        <property type="entry name" value="SENTRIN-SPECIFIC PROTEASE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46468:SF1">
        <property type="entry name" value="SENTRIN-SPECIFIC PROTEASE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="6">
        <location>
            <begin position="1"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="224"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="233"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1897819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="248" mass="28463" checksum="764301C94D2F9A3D" modified="2025-10-08" version="1">MSPHQPYLSYHDILCTLTAAFDPLSDFPISALRNDWLTDNNIAFWEEYLEREVLPKYPKARVILLRPSMTFLMMKDPDLKSVKSALPDFRHISHIFLPINDNRNVSVAEGGSHWSLLVVSLLDRVAFHYDSLGRSNYCEAKNATQIFGRLLRIPLTFMHLDDTPQQENGSDCGVFVCILMRHLLVKRLLCVGAREQVSMSLANKMVDSRGARKEMLNIIEQLRKEGERRRSLSRSSSPYSSKTPPRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBX7</accession>
    <name>A0ABR3ZBX7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000039">
        <property type="protein sequence ID" value="KAL1897802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="185" mass="20941" checksum="DA43BE927EDE2DE1" modified="2025-10-08" version="1">MSPSPATTRQGVQDSESATRNEDLTVNGAQLTNTTFVFAQNPPVPEYLLTTVTFAWKMALQASAPKFYSDDVSPCSIVASIAKTISDDALLTARKVSLMFRSLRYQPKTGIKPLIDQVEKIRHIQRDIVEKFPERQFIWAVYQLILEYHSCITLIPNLEDATEWEAFSSLLLAKQDFLQSQINLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD75</accession>
    <name>A0ABR3ZD75_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Kynurenine 3-monooxygenase</fullName>
            <ecNumber evidence="10">1.14.13.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Biosynthesis of nicotinic acid protein 4</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Kynurenine 3-hydroxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 13" type="primary">BNA4</name>
        <name evidence="13" type="ORF">Cpir12675_001840</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>L-kynurenine + NADPH + O2 + H(+) = 3-hydroxy-L-kynurenine + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:20545"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57959"/>
            <dbReference type="ChEBI" id="CHEBI:58125"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.13.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the aromatic-ring hydroxylase family. KMO subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.9" evidence="10"/>
    <dbReference type="EMBL" id="JAWDJO010000031">
        <property type="protein sequence ID" value="KAL1898636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004502">
        <property type="term" value="F:kynurenine 3-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01971">
        <property type="entry name" value="Kynurenine_monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027545">
        <property type="entry name" value="Kynurenine_monooxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46028">
        <property type="entry name" value="KYNURENINE 3-MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46028:SF2">
        <property type="entry name" value="KYNURENINE 3-MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0274">FAD</keyword>
    <keyword evidence="2 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 10" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0521">NADP</keyword>
    <keyword evidence="7 10 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 10" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="460"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="12">
        <location>
            <begin position="3"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1898636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="506" mass="57603" checksum="3C6DFBAB2CC95897" modified="2025-10-08" version="1">MQKTVIVGGGPVGSLAALYAARRGHEVEVYELRPDLRDPSTVPLNFTRSINLAVSERGINAMRNSGFPDLLEDVFKSALPMRGRMIHGRKVDGTFYEEAQDYDPFGRTIFSMDRTILNKTLLDTLEAQPNVKIFFNHKLTGVDFRKNEAWFEINGQSPTEKPRGEIRISFDFLIGADGAHSLTRYHLMKFTRMNFQQEYVETLWCEFHIDPLEPDSSCESKPRFAISPGHLHIWPGKDFMFIAIPSDDGSFVCTLFMPSTEFSKLEADVSTIPEFFDCHFPGVTELIKPSQLVESFTKNPHLPLVSIKANPYHYGSSAVIVGDAAHAMVPFYAQGLNCGMEDVRILFSILDKYAKLIQDNSPDGSSDVLMLQLSQRAMALNEYTEVRVPDAHVVNDLALQNYIEMRASVLSRTYLLRKWLEEKVSVYFPALGWKTRYMRISFGNERYSEVLKKTEHQGRVLSRVILASLVSPFFFGAVFLWGRRHQNSGSMIMNGMGWLRYITNVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF36</accession>
    <name>A0ABR3ZF36_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_001496</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000024">
        <property type="protein sequence ID" value="KAL1899303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051019">
        <property type="entry name" value="VLCFA-Steroid_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43899">
        <property type="entry name" value="RH59310P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43899:SF13">
        <property type="entry name" value="RH59310P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1899303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="336" mass="36825" checksum="2E566AA10BF0D90D" modified="2025-10-08" version="1">MAIPLSLLLAFASIGIIASIKWVYSLIRFIELHFLHTRHPLAVYQRSRRPAYALITGASAGIGLGTATALAHQGFGVILIGHLPDELALAKDFIRAQVRGAKVETVVLNAITASSSSVQKLASDLFAKDFAISVIINNVGGMPISNTPFRPFSTYLASDIDRVIDMNARFMAQLTVNMIPLLNAHRSSPLERSLVLSLTSAAAVGLPYLTMYSATKAFDLGLACGLAREFEMVPETAHIDSLAVMPGEVRSQGNCLGVPKGAPKWYSYGCLIVKTVDVAVRQGRRILVPYWLHHVQIRAMDYIPEKLLTREVAKTAILKRDEFNARHEQTRSTEMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG71</accession>
    <name>A0ABR3ZG71_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PTC7</name>
        <name evidence="4" type="ORF">Cpir12675_001293</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000019">
        <property type="protein sequence ID" value="KAL1899710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039123">
        <property type="entry name" value="PPTC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320:SF1">
        <property type="entry name" value="PROTEIN PHOSPHATASE PTC7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="3">
        <location>
            <begin position="49"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1899710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="365" mass="38936" checksum="13B982389AAAE38E" modified="2025-10-08" version="1">MKYSTSSSDTSPTSLGSPHLSYGVAAAFIGKDLSWHATRNIHHFNPHKRVQPVKKTREQRPPSGHDAFFISHLGDTSAVAFGVADGVGGWVDSGVDPAEFSHGICDYMAMVSFAYPGHDPVSPKAIMQKGYEAVCNDRTVIAGSSTAVVGVAAPNGAVEIANLGDSGFIHLRLGAVHAYSKSQQHSFNTPYQMSVIPPSMAARIATFGGAHLSDMPHQADITHHNLQSGDVLMLASDGVWDNMFNEDILKVVGKMMLASGAWAIDDDGAVQVAPSISEMVKVPELSADGPQALNSQATLQSLVASRIALTAKANSHETRRDGPFAKAMKRVNRRERWVGGKVDDIMVVVLIATQDGTMVPVKSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGU0</accession>
    <name>A0ABR3ZGU0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Flap endonuclease 1</fullName>
            <shortName evidence="10">FEN-1</shortName>
            <ecNumber evidence="10">3.1.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Flap structure-specific endonuclease 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">FEN1</name>
        <name evidence="14" type="ORF">Cpir12675_001564</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
            <location evidence="10">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
            <location evidence="10">Nucleoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Mitochondrion</location>
        </subcellularLocation>
        <text evidence="10">Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="10"/>
    <dbReference type="EMBL" id="JAWDJO010000025">
        <property type="protein sequence ID" value="KAL1899280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09907">
        <property type="entry name" value="H3TH_FEN1-Euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09867">
        <property type="entry name" value="PIN_FEN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00614">
        <property type="entry name" value="Fen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023426">
        <property type="entry name" value="Flap_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019974">
        <property type="entry name" value="XPG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF9">
        <property type="entry name" value="FLAP ENDONUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00485">
        <property type="entry name" value="XPGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00841">
        <property type="entry name" value="XPG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00842">
        <property type="entry name" value="XPG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4 10" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7 10" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2 10" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG N-terminal" evidence="13">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="XPG-I" evidence="12">
        <location>
            <begin position="146"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="357"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="357"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="384"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1899280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="394" mass="44336" checksum="0FBF6926049FF05A" modified="2025-10-08" version="1">MGIKQLFSIIKENAPAAIRESEIKAHFGRKVAIDASMSIYSFLIAVRSNGEVLTNEDGQTTSHLMGMFYRTLRIIDNGIKPVYIFDGAPPKLKSGELARRTARKQEATTALEAAKEAGDAEEIEKFARRTVRVTREHNAECQMLLKLMGVPFLIAPTEAEAQCAALARGGRVYGAASEDMDTLCFDSPVLLRHLTFSEMRKEPIQEISVSKVLEGLEMDRKQFVDLCILLGCDYLDPIPKVGPTTALKLMREHGSLEKIVEFMKNDPKKKFVVPDPWPYQDARQLFFEPDVKPAEDPECDFKWEKPDVEGLVQFLVVDKGFSEDRVRSAAAKLEKNLKSSQQSRLEGFFKVVPKTQEEKSALKRKAEDKNLAQRKRMKDEKKAKAAAKARPRGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHA9</accession>
    <name>A0ABR3ZHA9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_001152</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47429">
        <property type="entry name" value="PROTEIN TWIN LOV 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47429:SF2">
        <property type="entry name" value="PROTEIN TWIN LOV 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0157">Chromophore</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="335"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="20"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="102"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="441"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="25"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="469"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="491"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="504"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1900046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="730" mass="80203" checksum="7F3BE424A0E69546" modified="2025-10-08" version="1">MEPPVSIHVRRRSTPIFFSSRPSPTAVSPLSSTISSISEAPSIATTSTTATTASTNSTSSPILSLGPPRSRPRPISDNSVYSRRDSGLSFNVTATKTATTINSTSTPATAVSSKVAAVSKQQQHHHQSDSTPPSPRYIESKTLGNRVRSLNNIRALKLQCQNQQQASPSAGQAEIIDLLNPDTIRQTFEDDAIMARWLAFARSRDCAQNIEYMLRIRKYIRDVHSLQDSITSISSTFTSLSAPSPITLPPAMLRAVSSDARQVSNTYIPRLETLFLESQFYLEQNAIPDIYYAFIRNQLAMSISAHLSLSVPCEASPFSSLGESFCLSDARAPGYPITHVSDGYTNLSGYSRSEIIQHNKRRLDGPATNPDTLKRIQTALKRGEESVELLVNYRNDGTPFWNLMYLCPLTDALTHDVRYYLAAQVDVTEGISSTDDVLGTLTFGSQKTEPKKPTTTPQKTHRISRMYSLRSTPTSATPQTLDKEAVSSPLSRRRMFPSFRKQHPYQPRQKQSQEQQQTPQTPIESAPETPAAQPKPSLQAVDALLHTPQDVAALCPTDDINAFYTPYTRFLILSVVQPPKTHHPHPWTPLDSPSPSLSRKKHATVSQPALAVSFCSKPAQEALGLGHPRDVLGHDVFDILANAHCSSLTKSSKAAVHDRVLHDGNSLIIDIVLPAMNRGGGSCPDLPGFRMKKSHKFLGHWTPLKDADGLVCWIMLTLSPVVRAPPSTFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHS8</accession>
    <name>A0ABR3ZHS8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Succinate dehydrogenase assembly factor 3</fullName>
            <shortName evidence="8">SDH assembly factor 3</shortName>
            <shortName evidence="8">SDHAF3</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_001299</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 8">Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the complex I LYR family. SDHAF3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000019">
        <property type="protein sequence ID" value="KAL1899714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20270">
        <property type="entry name" value="Complex1_LYR_SDHAF3_LYRM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008381">
        <property type="entry name" value="SDHAF3/Sdh7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13137">
        <property type="entry name" value="DC11 ACN9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13137:SF6">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13233">
        <property type="entry name" value="Complex1_LYR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1899714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="172" mass="19563" checksum="F536F899C10CC1AD" modified="2025-10-08" version="1">MPNVVSALRAAPVHTTLFSRGITNTITGISTRTSPNISRAYASISPAAAAARDAARMPLLRPLALYRRLLRAHRLYLPAEMRLLGDEYVKAEFRAHQKLDNPSQVIGFLTEWQMYLQQVEGDKWKGERMDFTKIERLSEDQMVQLYELMQSIKSPSTEPISGDTPDKQWTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI13</accession>
    <name>A0ABR3ZI13_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">G protein-coupled receptor gpr1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">GPR1</name>
        <name evidence="9" type="ORF">Cpir12675_001145</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023041">
        <property type="entry name" value="Glucose_rcpt_Git3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022596">
        <property type="entry name" value="GPR1/2/3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF37">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR GPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11710">
        <property type="entry name" value="Git3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11970">
        <property type="entry name" value="GPR_Gpa2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="460"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose receptor Git3-like N-terminal" evidence="7">
        <location>
            <begin position="35"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="G protein-coupled receptor GPR1/2/3 C-terminal" evidence="8">
        <location>
            <begin position="449"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="290"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="353"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF11710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF11970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="637" mass="69927" checksum="C5EE50CB637DE4D6" modified="2025-10-08" version="1">MSSFVAAVNGSSFIETPNALNGTLARISNGETLGLHIVSLVFSTISLSVSATALYLFLTSRRSFRHDLVMLLIISDFTKSLWLFLFPLISLISGPIASASLLCQISGFCLSFGLEAFDIAVLLIAAHAFLSILHPVATGGSSNGIYPYRFYAYAIFVCFPMISASLAFLNKPLGYVNTGEYCYIASHPIWPSLFLSWIPRLFTFVTIVVLYVFLYNHVRDVMRNYEKTSYSHNHAKLAQLSQVSRLDVYQLDALQPLPPIACHGLIPHSCSSSFADSSYPRHDSNATLVSDLQSTETSSSPLLPQSTPNTTSLRSSQAIRWKMPDFSGSMDNDSSTSKNTYRMRLYSDPEPVAPELLISSPSDEDQKAPQKPNHSGLPGTGPVRPGISPLPSANPSFDGPTRGSSFASAITSAFRNARGSCSSSSTAATTAAAETPSFTLRNDLEMARTRSRVFHQLRLMFIYPIAYIGIWVFPFACSMMRIHSYHTSSSIAETGVGSESAPYALVIASMVSLCVQGTVDCGMLLAREKPWREKLQRGTGWWWGSRSRNGSQYTVGRTREEMLLDSKIARQRRVYEINERKAAAAEAIVAQKTQSAKGERGMRNWWDVHDEGDDDEQEVAAMSFLDMSYGDMGKGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI63</accession>
    <name>A0ABR3ZI63_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vacuole morphology and inheritance protein 14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000982</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000013">
        <property type="protein sequence ID" value="KAL1900400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026825">
        <property type="entry name" value="Vac14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16023:SF0">
        <property type="entry name" value="PROTEIN VAC14 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16023">
        <property type="entry name" value="TAX1 BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12755">
        <property type="entry name" value="Vac14_Fab1_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="HEAT" evidence="1">
        <location>
            <begin position="86"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="279"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="364" mass="41245" checksum="DD90063CCE394EA4" modified="2025-10-08" version="1">MDNSIQRALGDKFYDKRKLGALDLERVVRNLVASQNYKTINVIIDQLCNDFAYQSSIPHARNGGLIGLAAAAIALGHELPQYLRKLIPPVLACFTDPEARVRYYACESMYNIAKVAKGEILYFFNHLFDCLCKLCTDHELSVKNGAELLDRLIKDIVSENSVEYQSVVPKEKSADDDQGGPDEYELAFSLPKFIPLLKERILVTNPYARQFLVGWIELLDGIPDLELVSYLPDFLTGLLRFLSDENRDVHIATRKCLDRFLSEIKRIARIRKGIAESKKSNEGGKRKRVESVDSDSCQVDLEDGDHNDSDGYDDDEGNLDELQESEEEWQPGQDVEIDYSRILDILTSTLEHDTSLGKLSQSWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ41</accession>
    <name>A0ABR3ZJ41_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_000830</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the OSBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13292">
        <property type="entry name" value="PH_Osh1p_Osh2p_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018494">
        <property type="entry name" value="Oxysterol-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF205">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01013">
        <property type="entry name" value="OSBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="5" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="180"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="323"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="10">
        <location>
            <begin position="413"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="530"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="761"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1263"/>
            <end position="1282"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="721"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="546"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="611"/>
            <end position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1900696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1282" mass="142887" checksum="587A0EDD3A8F8899" modified="2025-10-08" version="1">MSDTGESLAHKRSRSSAAKVLLRRKTTEPRDRDDTSATTEEDTGLQLDTRPNTLNVAPSPSKATPSSPQMQPSRGHSSKLSTTSMTASRVPSHPSIAASVSPPTVAVSVPSTHPTRNGSVNYTDKGAVSLEQSLRKFRIVEALRNGDTASISKAIRETWESASRRSTSSASAAPVTGPLEDTTILHLAIQCAEIQVIEYILSDGATLIDINARDKDGNTPLHIASQQGRTQVVQLLLDQPGINDSVVNFQGRLPIDLSRSPDIFQQLHLSKTLFAETKIKQVQDLIADQNYGILRDVLEEPRLKSVLDVNSTDFVSEPITAQSGGTLLHEAARKRDSQLIQLLLLHGADPFKRDRKGKLPQDVTKDDTTRAMLKRSPAAQAAQRGIQEKAVLGAASQGGSASLTSDPLAGREAREMRGYLKKWTNYRKGYQLRWFVLEDGVLSYSKHQDDAGAACRGAINMRIARLHMSPDEKTKFEIIGKSSVKYTLKANHEVEAKRWFWALNNSIQWSKDQAKEEDRQRLRRDEFLRHAKEHEKPSQLAPSEGASENVSVSEFGGSSSKAAQVTRTASTSRLNRWPDNAGTSNGSGDEDDRYDHETRPSVNPADSVYHDDDDDEEDNYLDDSSARNVAPSKDAFSIIVQSARLQLDTMAQVNSALMSQVPRQGTSATAPSLADPAVVQALATYDGAIRSLTGLIGDLLKIAKDREGYWQSRVDREIDMRRMWEESMAKLAREQEELETQYSQAEKKRKMTKRALRQALTAEASSAPANTIHEHDSEDELARANTGFTSANRKPPIDISLSDFESDDEEEFYDAVDAGDIELAEMPPSEEAGESKAIMVVNDDEHDISSSFRGYENGIRTRLKLDEDNRPKVGLWGILKSMIGKDMTKMTLPVSFNEPTSLLYRCGEDMEYVELLDQAAERSDSMERLIYVAAFAASEYASTIGRVAKPFNPLLGETFEYVRPDKNYRFFIEQVSHHPPIGAAWAESPRWTYYGESSVRSKFYGKSFDINPLGTWFLKLRPTSGGKEDFYTWKKVTSTVIGIITGNPAIDNYGAMEIKNWTTGEVCYFEFKPRGWKASSAYQAAGKIVDASGKVVYSMGGRWNSRIYARKTPGYEAALDDPGDGAQNGSINDPNKPFLIWKANPRPAGIPFNLTPFVLTFNHIDETLRPWLAPTDSRLRPDQRAMEEGEYDFAASEKTRLEEAQRARRRQREQRGEEFKPAWFRKAKCEITGEEYWKFNGEYWKLRDHSGPNGDPGVWDGLEPIYEDFKGPPPRALTESSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ85</accession>
    <name>A0ABR3ZJ85_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_000825</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13948:SF3">
        <property type="entry name" value="FI21118P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13948">
        <property type="entry name" value="RNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="G-patch" evidence="5">
        <location>
            <begin position="616"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="229"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="380"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="416"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="458"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="544"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="423"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="458"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="557"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="567"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="592"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1900691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="697" mass="77088" checksum="33FBFB3BD77A049C" modified="2025-10-08" version="1">MAANILIGPVPRDYSGSPPRNQRHTFRYRRAQNQNENQNHQAELSYDDVPETGSQNNHGSPEGEDDDDHEDGRIYESDMSQDYDDEDLSSYGSYQHRHHDSSQYLDLDRNGGRGQPAQYSRSRRFQSVEDSMAWMGENKPVVSLCFPEKSDIPEKRLTARLYYGSSRPRDHHEGEGNSQKQNRKRADLASYRQQLTGATDTSTTPSQILVFYPLAPTVTEEKLAAGARQLEKEEKPNAPMKGEGAPKLKSTAPIGDTTGLGAKKGSIYRVILIRDTITNASLNYGFAEFWTLDDAMAAMAKFQKSRTFTIEDAPVAVSTIHLGVFVPETRDVLPNIEKQSFHPLFNPRIRVRYRDLHVYPSIRMVTSEPPQGTILADMAANSAEDSRKAKKRRGDSLASGTAKKPVVMAGQMAMWQKKHAEISQPNDGEPSKSSVNSIPVGSKNAPIKISLGGLSKSIGMSTTESKPTTAPSESQLTDVSDKTCPTADEKPVSFLDRDKLQCLLCMMKYKSLEDCDTHERSRNHAMAMQDEAKVKAATARIISRSNKKIAKEPKEPSTLSTTTASQYRDRAQERRVAFNQPEQPTTCKPKSKAKDTAETRFKESDNVAAPEKPSIANSKGSSLLAKMGWTAGTGLGSNGSGRTEIIATNAYQEGVGLGAEGSNLGDAQVLAEKKTLNRHGDYLETVQDKMRERYKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJR3</accession>
    <name>A0ABR3ZJR3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ORC6 first cyclin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_000944</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ORC6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008721">
        <property type="entry name" value="ORC6_cyclin_first"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05460">
        <property type="entry name" value="ORC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ORC6 first cyclin-like" evidence="7">
        <location>
            <begin position="2"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="91"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="379" mass="41976" checksum="FE4629584183FDAD" modified="2025-10-08" version="1">MPSHGPIIPPQLVDLAGSLVVQSRQRASTLKAEEEIARSYCCAHLACDRLKIALNLPPIEPRPPIPPRVYKRLYTHLDNVLPKTAMRVNATRARPTAPPTAPPLSRNRLAGAQPMAGRVPQKPSTASRLMGGSVESSTGKDRNTGVPKWMIPVARYMCVKAEQRFMAPSVFGGIDYIVAPGGKRTKDPWILTNLGAVVMAVFVLVVERGAALLHASRPKDAYTKGEGTNTTDNTDGAREYISPKMRKLAVELAIRARSEITSITEKSDWEGWSAPTARTLSQALERIQSEEEWINADWMGSVKDVVARILEANERVRSGRQKAAQSSGLVQRSDTMMQEKWEFLNEKRRREQRAWEETILMKISQLESSSGGLSMEVDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKA3</accession>
    <name>A0ABR3ZKA3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_001198</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000017">
        <property type="protein sequence ID" value="KAL1899974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007632">
        <property type="entry name" value="Anoctamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049456">
        <property type="entry name" value="Anoctamin_N_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049452">
        <property type="entry name" value="Anoctamin_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308:SF73">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04547">
        <property type="entry name" value="Anoctamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20877">
        <property type="entry name" value="Anoctamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="441"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="552"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="625"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin alpha-beta plait" evidence="8">
        <location>
            <begin position="21"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin transmembrane" evidence="7">
        <location>
            <begin position="181"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="671"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="719"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="676"/>
            <end position="693"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1899974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="781" mass="87510" checksum="98EF49C79B13198E" modified="2025-10-08" version="1">MPSFKTFYSEDPPEGYSTNLGVDYVILYKVPENGSEKAEAEASYAQLIKQLTSIGLATEVRPGEPGTLLIFVKVASGQLFSDQVYRARLADWLHGVRATAPSQELSEAFRQERVTPAERLRLVHRMLVKPRNEGGAGITPGTGTWRFVDSLFPLHNHVLNRHWLQRFSTIYLLEAADLDEIRDEIGEGVAYYFEFIQTYFVFLIFPAALGLGAWLLLGQFSWIYAAACSVWSVVFFEYWKQKEVDLAVRWGTCGVSKIQLDRSQFIFDREDVDPVTGEPVKVYSPFKRLGTQLLQIPFALACVVVLGGLIVTCNSLEIFINEVYDGPFKKYLGLLPTILLSGLTPTFSVILTAIATKLTNMENYQTETAHQAALIQKEFVLNFMTSYMAAFFTSFVYTPFGHVIAPFLTFWHNVASAMTMGNFQIKAHEFTANPRRISDQMFFFTVTAQIISLATEVIVPYIKRKVFKTVKEYKYEKDAIQQQAADEDGKFIARVQAEAELEVYDVNVDYREMVIQYAACCFLVNNWIELRSDALKITVGSRRPIPWRTDSIGPWVNALGFLSWLGSITSAAIVYLCSNSTSATGTAMPDMAENTTSATTPSLHGLDETGKPTIRVSTVEHSSDFTAWGLLLVILLAEHLYLAMQILVRYVMSKLDSPGLQKERKERFQMKKRMLLSTTTTREASSGSSTAEDLSSAKSSLASAAGGTSLKNGVPGIEESERIIRNEQDKDIGRAERRGQKIPEEVFWHKHQTMAETIEAGRSLIMDMKSGGTAENTKKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKI9</accession>
    <name>A0ABR3ZKI9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Anthranilate phosphoribosyltransferase</fullName>
            <ecNumber evidence="5">2.4.2.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TRP4</name>
        <name evidence="5" type="ORF">Cpir12675_000760</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.18" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004048">
        <property type="term" value="F:anthranilate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="entry name" value="Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005940">
        <property type="entry name" value="Anthranilate_Pribosyl_Tfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000312">
        <property type="entry name" value="Glycosyl_Trfase_fam3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017459">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01245">
        <property type="entry name" value="trpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43285">
        <property type="entry name" value="ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43285:SF2">
        <property type="entry name" value="ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02885">
        <property type="entry name" value="Glycos_trans_3N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl transferase family 3 N-terminal" evidence="4">
        <location>
            <begin position="34"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 3" evidence="3">
        <location>
            <begin position="113"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1900747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="415" mass="45044" checksum="714CDC8956C53A33" modified="2025-10-08" version="1">MAFSQAPIAGSSASATVVKTDIKPLLQSLWPVTSSVTSAEIADAISLFFTNQISESQAASLLICLHFTQLDIRADVLSECAQVMRNAAEQIDASGLQALIQRRGLSVGKYNGGLCDIVGTGGDSHNTFNISTTASIIASGLLLVSKHGNRASTSKSGSADLVNSMAPRPPILNAVTPTSLIDIYTRTNYAFLFAPVFHPGMRYVAPVRKQLPWRTIFNNLGPLANPVEAILEARVIGVARRALGPAFAEALRLAGVRKALIICGAEELDEISCAGPTYCWMLQENAQGEVYVREFTVSPEDFGFECHALSEVESGKEPKENAELLHRILNNELEDNNPLLQFILMNAAALFVVSGMVEADESDMGEGDDRKVVMERGPGDCRWKEGVRRARWCVKSGAAWKQWLEFVNVTNDLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKQ0</accession>
    <name>A0ABR3ZKQ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">1-acyl-sn-glycerol-3-phosphate acyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.51</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SLC1</name>
        <name evidence="6" type="ORF">Cpir12675_000503</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA</text>
            <dbReference type="Rhea" id="RHEA:19709"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57970"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.3.1.51"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="4">The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.51" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003841">
        <property type="term" value="F:1-acylglycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07989">
        <property type="entry name" value="LPLAT_AGPAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004552">
        <property type="entry name" value="AGP_acyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00530">
        <property type="entry name" value="AGP_acyltrn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10434">
        <property type="entry name" value="1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10434:SF11">
        <property type="entry name" value="1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="5">
        <location>
            <begin position="65"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1901270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="250" mass="27346" checksum="3F41CC689BEC92BE" modified="2025-10-08" version="1">MAVYMSGMIASAAGFFAAIVMRMVGQNHSAQWFGGRVMKHICSTLLGLSFEVIDPKNHLGTVQPAVFVGNHQTELDVLMLGCMFPTHCSITAKSSLKKVPILGWFMALSGAIFINRTNSQGARGVVSAAGQEMKRRNQSVYMFPEGTRSYSKEPMLLPFKKGAFHLAVETGVPIVPCVVANYSHVLYAKDWVFNAGRIPVKVLDPIPTKGLAADDVSALCEKVRKLMYEELIVLTSEAQGKKFEMPPMDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLV5</accession>
    <name>A0ABR3ZLV5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Telomere-associated protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_000588</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11660">
        <property type="entry name" value="SANT_TRF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052450">
        <property type="entry name" value="TRBD-Containing_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46734:SF1">
        <property type="entry name" value="TELOMERIC REPEAT-BINDING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46734">
        <property type="entry name" value="TELOMERIC REPEAT-BINDING FACTOR 1 TERF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="4">
        <location>
            <begin position="220"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="3">
        <location>
            <begin position="220"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="140"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="195"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="318"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="513"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="11"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="195"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="318"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="343"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1901222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="556" mass="60571" checksum="B1B217046B72F29F" modified="2025-10-08" version="1">MSSKKFIPVTTPGADSSSSLPSATSGPTPARPGGSLPNFPLPYPSSSVANNLYQPDADYGFSYWNEQPPKQNDAPPSHTLPSIQEVYETNFIDPRDTYRVSSATYELPPVLPRLEDISLSTKSGSSSRTIGASGIPVYEATHSHSQSSSQPQPPQNQLQTQPQSQPLSKINIDALTHLTDVPAFNPSFPEFSLGTADSTALSNPTPAIRHSPSPPNVIRRSKKGRRKWTDAETEKLILATEKHGIGAWATIAKDPAFVFNDRSAADLKDRFRTCAPPELLCRFNTRTSESTGQELSSSSNTHILPSIAILAADSASKPQPATTVKSFPSNILNPSAQDGPVNSLGSTDSTLKPSSQNKGSFPSNILNDGPGYVTPSPPRDQDEPVKRPRPKRSHRRTMEDIQKLGITGPFKVTARRGRRRFTVEEDMSILKGLIHYGPLWSKIRNDPARICIQERHPTDLRDRIRNKFPAIFKALNAKTNKRGVEGFLPEGLEPHVIELVEDTLKQLSAALDASDTQTSEYHHSDTGDPGSVSAHASDTGEDNTPAYNVLRLLQAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM66</accession>
    <name>A0ABR3ZM66_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glutamate 5-kinase</fullName>
            <ecNumber evidence="10">2.7.2.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PRO1</name>
        <name evidence="10" type="ORF">Cpir12675_000520</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.11" evidence="10"/>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004349">
        <property type="term" value="F:glutamate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04242">
        <property type="entry name" value="AAK_G5K_ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21157">
        <property type="entry name" value="PUA_G5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="entry name" value="Acetylglutamate kinase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="entry name" value="PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00456">
        <property type="entry name" value="ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041739">
        <property type="entry name" value="G5K_ProB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011529">
        <property type="entry name" value="Glu_5kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005715">
        <property type="entry name" value="Glu_5kinase/COase_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019797">
        <property type="entry name" value="Glutamate_5-kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01027">
        <property type="entry name" value="proB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43654">
        <property type="entry name" value="GLUTAMATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43654:SF3">
        <property type="entry name" value="GLUTAMATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000729">
        <property type="entry name" value="GK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="Carbamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00902">
        <property type="entry name" value="GLUTAMATE_5_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PUA" evidence="9">
        <location>
            <begin position="295"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="401"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1901287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="430" mass="47112" checksum="3A6D76DBFF71252C" modified="2025-10-08" version="1">MKGTKSLTVVIKLGTSSIVDEKTHEPLLPILSLIVATAVELRKEGHKVVIVSSGAIGVGLRTMDVKKRPKHLSSLQALAAIGQCHLIHLWDSLFSHYRQPIAQILLTRNDIADRTRYLNAQSTLMELLHMGVIPIVNENDTIAVAEIKFGDNDTLSAITSAMVHADMLFLMTDVDCLYDKNPRTSPDAKPIEIVRDISEITADGSALGTGGMSTKIVAARLATSAGVTTVITRSSAPGNLPKIARYIQATKRASRNLDNTVVPIEQPPLHTRFLPIADPIRDRHFWVLHGLAPHGTVYIDEGAHRALIRRAGLLPVGVVGVEGHFGHHESVRLVVAKRRQTPDEHGRLWEDDQQEIGRGLTNFSSSEITRIQGEQSSKIKNILGYADSGYVAEREFISLLRNESRPPSPGDERTPSSVTTPRSERRADSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMA8</accession>
    <name>A0ABR3ZMA8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="140"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="240" mass="25822" checksum="3F4D6CBB96A46E3E" modified="2025-10-08" version="1">MSTRMVIVNPPVESPLTPNNGRIAPYSVVTRFWTGPKFSEPTANLRRHYGRAGGLSPRIPRQPMTTQDPGCAHVLWPPVPVPVPVSLPVPGYVSRCYAPLQSGSRSPSCYCPSYTGPQLDIPPKSVQDTHNHGEKCGETQQQTGSPQQPQPQNYHQPAHIDCFCPSYLAQWCGLSNPCYYDVKGFLCRGCGYATSTSECLSTVDSDLETVTDSISGSSSDTASSVSCDVVYSTAASSEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN94</accession>
    <name>A0ABR3ZN94_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNase III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_000070</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11207:SF0">
        <property type="entry name" value="RIBONUCLEASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11207">
        <property type="entry name" value="RIBONUCLEASE III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00636">
        <property type="entry name" value="Ribonuclease_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RNase III" evidence="3">
        <location>
            <begin position="176"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="78"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="439"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="440"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="451"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="460" mass="51014" checksum="AA8A3F76DE853C41" modified="2025-10-08" version="1">MSKRSREESADGQLEIQGCSKRSKEESKDAISAILNNSDELIECLQALKGDTEKKRRLEKQLANLTFKLLPALQSLANSSKASRNARKEETDAKEAPSSIEQEAPAKNIEPITNEAQLNTRPLIMAHARDHPEALKTGASEVQSHKKGIEAPWYYLTTGWTSDNIHPEIPPLPVVDEELKTAAFTHSAFTNNGKLLSYERLEWLGDAYLYALSSAFIFQTFGSLPTGRCAQLRESLVKNTTLASYFRQYSFGKYARVPPERQRATLSNVPDCDKETIKVQGDMFEAFVAAVVLSSPEYGVARVSEWLKLLWARTLGKQLRDLGRSTTGTGAQELGEGGMDTKLGAKTRLANHIQVPGVLLEYRDMACKKKDRDTNLPLYSMGLFLTGWGEKEKMIGMATALSKKEAGQKAALQALDSNKLMKQYHAKKRAFIEARTSQNTAAATKTAEQASAEREITKFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNU5</accession>
    <name>A0ABR3ZNU5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000022</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="143"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="285"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="294" mass="28222" checksum="5668B8C3296F669C" modified="2025-10-08" version="1">MPGIPPNALRLLKTRVKALFKKKTTTAAPAAETSTTTPAAIAAAPVAAPAAAPAAASSTATAPPVALATPTAAAASPAPATAPTATETSKVDKPVSESATPPAPAVTAEATPVAAAVETSAPAAAVPAAVPAAAPAATEVKPTDVAPAAAPETSAAPTALAAAPAPATSTATETPIAEASGTRDSAVEAPATAVPIAKEAAGEAPATTAAAAVTEAPTPATEAAVVESSTKTEAPAATAEPETSKIDEPKTEDPKTEEPETEEAKTEEAKPEEPNVNEKKDDSVAAPTATPTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP75</accession>
    <name>A0ABR3ZP75_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Kinetochore protein Spc24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">kri1</name>
        <name evidence="5" type="ORF">Cpir12675_000542</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KRI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018034">
        <property type="entry name" value="Kri1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024626">
        <property type="entry name" value="Kri1-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14490:SF5">
        <property type="entry name" value="PROTEIN KRI1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14490">
        <property type="entry name" value="ZINC FINGER, ZZ TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05178">
        <property type="entry name" value="Kri1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12936">
        <property type="entry name" value="Kri1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kri1-like C-terminal" evidence="4">
        <location>
            <begin position="554"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="151"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="403"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="645"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="312"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="67"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="156"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="191"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="212"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="466"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="497"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="507"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="659"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="673"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1901309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="689" mass="78339" checksum="5936749DAC47598F" modified="2025-10-08" version="1">MGSTKATESAASKKKALFDDNSDSEAEGGSKIKINTEFAKRFEHNKRREEKQKLEEKFKREGRSLNSDSDSGSESSSGETEDEDGFLATEALDAEISATLNAIRKKDPRIYDKSAAFYTAKSTADADADASKSSKEKPLYLKDYHREQYLKGAIEAPDHDEDKDVPVTYTQEQDSLKKSLVSSIHAAATTNDSNSDSENDGSSAFLKRKTPKKAELSHDGVHPERKVDVNKTLTEGDVANADKNPELFLSNFMSSRAWVPPDGSNWQAFGSEDEDSDIDRAEAIEHAYNMRFEDPEKSNEVLTTYARDLTNARSVRREELKGRKRLRELERERKAAEKQQRRDEKARFKKLKLDEMQTKLDQIRKTAGAWGKQLTEDELLKFLNDTWENDKWEDEMRKRFGEDYYEQQDTGFGSNGADSEDEEVEENGKMVKRPKKPTWNDDIDISNIVGEVDDDENGARQFTVADLEDSGDEGQVEAEAEDEDDLEDGDESEGSRPSKKRKTSKDHKKDRLAARKAAKTERSKLSAIVDLQMDLEDPDALALPTRRKKIRAGPAFRYRETSPNSFGLTPRDVLLAPSDTALKKFASIKKYAEWRLPEQKQEDTRRLGKKGRLRKWRREVFGKDFEKTGPTYGFKELFKAEEEKEKEKQAWRGADASEDDVKVRKADTEESGKKKKRRSKKSGKATAET</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YCP6</accession>
    <name>A0ABR3YCP6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006904</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000416">
        <property type="protein sequence ID" value="KAL1886037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="230"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1886037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="442" mass="48537" checksum="5B9225C62C0323A5" modified="2025-10-08" version="1" fragment="single">VRIDPTIPEMPLKRREDFILGRTLIEADPILHYSTLTLAIPAHIKAFAQKQRPPWSDAGQCPAVADPTLKLKNVLSSPAPPPAICRPDYSASFDPIAASSVFVWAAHIDPSVFDRPMRLIALDVAPYVRSIVYHDMQRRARSLSCSPAPDGTDRPAKKLRATRAALSAMDGGHRASVRVQDYFATCSGVDNAAVLATAGSSWPVLAYSQHQSAVTSHAAWFAVEMERLRIANEERLQKEARARAEQEAQAAQVRQQMEHQMQHQFAQNSGGMIMQIQPFIPPFGVPSIVQKQEGYPAHEGNPQMLQQQHQQQHQQQQAGVQPIPAYQYLAQPPNFKAPQQLQFPGPAPIYHATTGFAGNAQHQQVVPVPVLYRQQQHQSQIQQAGPQLYYHQVHPAIMGPAEPTVSGLSAPSDALVQEPSDGGLAVDPALFSSFNNDTEMIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFQ3</accession>
    <name>A0ABR3YFQ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">acetylornithine transaminase</fullName>
            <ecNumber evidence="5">2.6.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ARG8</name>
        <name evidence="11" type="ORF">Cpir12675_006680</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 4/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.11" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000349">
        <property type="protein sequence ID" value="KAL1887140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003992">
        <property type="term" value="F:N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01107">
        <property type="entry name" value="ArgD_aminotrans_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004636">
        <property type="entry name" value="AcOrn/SuccOrn_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050103">
        <property type="entry name" value="Class-III_PLP-dep_AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00707">
        <property type="entry name" value="argD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002325">
        <property type="entry name" value="PRK01278.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986:SF79">
        <property type="entry name" value="ACETYLORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986">
        <property type="entry name" value="AMINOTRANSFERASE CLASS III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 11" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="9 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1887140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="452" mass="47730" checksum="B3259D87FAF4CD64" modified="2025-10-08" version="1">MALRIAMRRQFPARMPSLTRAASTATATATTTATAVSHPDPMDGTESASIVSTSQPFMVATYSRPAPVFVRGSGSMLYDAEDRAYLDLTGGIAVNSLGHCDPEFTRILADQAGQLIHASNLYYNQWTGALSKALVEHTKASGGMHSASAVFVCNSGSEANEAALKFARKVGKVVDPSGAKHEIVSFHQAFHGRTMGALSATPNPKYQKPFSPMVPGHVYGTYNDVAAIDSLVTKNTCGVIVEPIQGEGGVNEGSVEFLSALAARCRAVGAVLIYDEIQCGMGRTGKLWAHSHLPPTAHPDIVTTAKALGNGFPIGATIVTADVAAKISVGDHGTTFGGNPLASRLGHYVLGRLSDPKLLAGVEAKSALFRDQLQALQKRFPDLITEVRGKGLILGVQLTRDPARILQEARHRGLLIITAGINTLRITPSLTIEDSEIVRAMEILGDAIVASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH87</accession>
    <name>A0ABR3YH87_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_006683</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000350">
        <property type="protein sequence ID" value="KAL1887126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1887126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="108" mass="11892" checksum="CD69343D15C76058" modified="2025-10-08" version="1">MSVPDLEPVQAGLSQPMQHLDNAFATVPPKSKNLRWELGMEGDRAGILSLRLSLNAKFGRAALAEIRASVYSKYVHQVSPLPLMCKHLRSSKPVQSKVCYELCALTTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHN3</accession>
    <name>A0ABR3YHN3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000294">
        <property type="protein sequence ID" value="KAL1887828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="659"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="665"/>
            <end position="682"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="967" mass="104099" checksum="44120DC9AE5BE376" modified="2025-10-08" version="1">MSTNYRIRKPYVLASLPRPFNPETGKFFVGEVFGHQLDQPRKKRTELIAAIDGESVNLYDITSSSLITSHPISPEQSFSCAPISLRMRLAKLHGTVRYTYAATRAATNAKGKPKQRITVFKDSVDANGKATSESLFVTVPSASPIILLETSTVLASVPNSRFDGNLVAVCKNGHILCFSPEDLTLRWQQSGNSLSQDEVTKFSALSIEHAAVVPAGDVIDGLFEGNSDIVSSAFSRAVTKDQKARADVVIFVACVTRGDVSERLLCALAVNPTATDADATVPALVRLHLASLPDPEKLPASADRQFRLHVPSGSLTMLSGDYIYVYDVSRALPQIAAAMYREAATSILRLTNHSIIATSATDAAVCNPSFGSVQALMSLDMATLKKPLKGEIQRFDMLANFKKLDLVVGLVGSLLVALPVEQPHFSAKKRQAEGLLIDSIGRGGPRDPLKKRARAEEETADIFTAPLPGTMTAEYMAEMRGAMDSADKALASGDIAAFDNLLAPCFGLTVSDDGSWDLECKKKQTYPLVDRRWVLYALSRAFALDEPSVENAANGEEERLPELRVALPTSNLIMYLTMAGHFTLRNLRAAFRESLENVDVPDAHLARGSVLRLVELDPGMDLLHSYLVSNKLAAVELLTVILVILRSLGFIPEEPNITKSLQGNSSSSEATTPATKATAAHSKSPDTNIDISMELDQLERELQTTEFYLSDETSIRARALTVAFAKLAAQSAPATVTALRATLQPHEVLSLIYVLRGELVRGSWTTRYQGQSDTICVSDNDQETGGVDAGPNADVDANAAPDGSITLIADLLSRCIDAVGMLGWMVHDSLSVAALSPSPNQTLELGDFLSALKLEVSAALQGLEECVVLEGLVGGAVRHARGIARAAKIEEKRAVERGGLRKASSAVKVGNGAVGEAAMLPLGSSWADIEPGWKVGKGGEIMQRTHRELEHLLSKGTRTYSLEKLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHV4</accession>
    <name>A0ABR3YHV4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Transporter of the ATP-binding cassette (ABC)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">YBT1</name>
        <name evidence="13" type="ORF">Cpir12675_006584</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000328">
        <property type="protein sequence ID" value="KAL1887351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18596">
        <property type="entry name" value="ABC_6TM_VMR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18604">
        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF353">
        <property type="entry name" value="ABC TRANSPORTER ATP-BINDING PROTEIN_PERMEASE VMR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="212"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="358"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="485"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="516"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="592"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1018"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1108"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1183"/>
            <end position="1204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1210"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="323"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="692"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="1022"/>
            <end position="1349"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1389"/>
            <end position="1637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="440"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="940"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1506"/>
            <end position="1527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="940"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="955"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1509"/>
            <end position="1523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1887351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1663" mass="183649" checksum="0038FBFCDF853E91" modified="2025-10-08" version="1">MAPETCSWPIWEVDDFTACFKTRYLNIAFPITIVSISCLQFIASALSRSFDSRRNDGYISISSDAAHQHTDLPPDTAAEAELCDSSEDDVEINGGRLALAKTNTRGSIAQADKPPAEHFLIIVEVIAIIGLIFANSYPLFHFDKVAGPIARTVSWSYVLILASLRLFLGNSKWRVPHLWNHTAAIYGCLWIIQLVLFRSALVHPIGLVERNISIIQLILSSLLWGIALTERKGNKTVVLEWEDGIEPSREPLASLLSLATFGWVDAIVWQGYNKTMEMDMVWNLLPKDKAAAIISNYRSLKKTSTLAFHLLKYFKGMLLYQCLMAALSGALTFVPTLLLRAIVQYIEQPTITPKNVVWLYVILLPTVDFVRSFADGMALWIGRKICIRIRAIMVGEIYAKALRRKAASGNEKSLGEDKKKAKNNGDSDDGIVARAKRALGLGKKKDDSDSEADADNDDKNGNDEQANLGTIINLMSVDSFKVAEITAYLHFLCAAAPVQLTLAIVLLWQVMGRSSIPGFVVMVILLPVNYTLALGFSTTSKKIMGATDKRIGITNEILQNIRIIKYFAWERRFGAMVDEKREKEIRALRSRYILWSIAVVIWNSVPVLITFFTFVSYTLIEKKPLLPSTAFTAMSLFMLLRIPLDQFGDMIAHVQETKVSIDRIEEFLMEEETEKYDQLGEDNVDDDGNKIIGIRDATFIWGGKNAVREDGSMAFRLLDINVDFQIGKLNIIAGPTGAGKSSLLMALLGEMTIIKGCVYCPGGRSREDVRVDPETGLANTLAYAAQSPWLVNATIKENILFSAPFDEDRYKAVVVACALERDFNILDDGDETLVGEKGISLSGGQKQRISVARALYSNSQHVILDDCLSAVDSHTAQWIFANCIRGPLMHGRTCIMVTHNTQLCVPASDFVVVLENGRIVSQGSPDDVIGSGKLGEEIQRSKGVSREISRLPSRVPSSVGSASNETAVEGSPDGTSPDATSKKDVTKKFKRSAMEENKAVGSVKWSVLILYLKSMGSWWFWVVALAVFWLQQLSTVASSIWVREWSNQYVPEKDNLSTMGINAQGSQVQAGVSSSIFAASTSAYLAPQTWLAVASSNGTNPEAPSVNATYYITVLAIIGLVGAFAAFMRDIWVFYGSLTASRSIHSRLIESVTRAKFKFFDVTPLGQIMNRFSKDLEAVDQEIAPIALSVAGCALGIIITIVLIATITPLFLVAAFFITLLFLGVGILYISASRDLKRLESVQRSPLFQQFGETLSGMTTIRAYGDERRFIRENLAKINAQSRPFIYLWACNRWLALRSDLLGDLVSFSAGVFIVLSLGKIDPGAAGISLSYAISFTENILWLVRLYAMNEQNMNSVERIQEYIDVEQEAPAVIEDSRPPHNWPSQGSVEFIDYTTSYREDLDPVLRNVSFKIEPRQKVGIVGRTGAGKSSLALALFRALEAETGKIVVDGVDISKIGLEDLRSNITIVPQEPTLFQGTLRTNLDPFEAFEDADIFAALRRVQLIGPDETPGAPPGTSTPSESNKNIFLDLSSPVSESGNNLSQGQRQLLCLARAMLRNPKVLLMDEATASIDYTTDSKIQGTIRELTSTIITIAHRLQTIADYDRVLVLDKGEVKEFAHPYELMIMKEGIFKGMCETGGEYETLLTAAKKAYDVKSASRHDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJA2</accession>
    <name>A0ABR3YJA2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoribosylaminoimidazole-succinocarboxamide synthase</fullName>
            <ecNumber evidence="3">6.3.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">SAICAR synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ADE1</name>
        <name evidence="11" type="ORF">Cpir12675_006386</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAICAR synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.6" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000292">
        <property type="protein sequence ID" value="KAL1887861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004639">
        <property type="term" value="F:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01414">
        <property type="entry name" value="SAICAR_synt_Sc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00137">
        <property type="entry name" value="SAICAR_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028923">
        <property type="entry name" value="SAICAR_synt/ADE2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001636">
        <property type="entry name" value="SAICAR_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018236">
        <property type="entry name" value="SAICAR_synthetase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010568">
        <property type="entry name" value="PRK13961.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00081">
        <property type="entry name" value="purC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43700">
        <property type="entry name" value="PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43700:SF1">
        <property type="entry name" value="PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01259">
        <property type="entry name" value="SAICAR_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01057">
        <property type="entry name" value="SAICAR_SYNTHETASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAICAR synthetase/ADE2 N-terminal" evidence="10">
        <location>
            <begin position="18"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1887861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="310" mass="34265" checksum="1BE205F2F6A85548" modified="2025-10-08" version="1">MSSTAGITSIQLPSLQHLATGKVRELFRLDDNTLLFVSTDRISAYDVVLDNAIPYKGAVLTLTSAHWFKVLSTLIPILKTHVVSLTPPASLSPTERALISNRSMTVRRLKIFPVEAIVRGYISGSAWAEYKAKGTVHSIAVPAGMQQSQKFAEPLFTPSTKAEQGEKDENIHPSEVAALVGGEKYAKRIEELALALYSAAAEYALERGIIIADTKFEFALDEKTDEVVLADEVLTPDSSRFWPADKYEVGRDQDSLDKQFVRNYLVENGLKGKEGVKLPENIVKATEQNYKDVFQRLTGQSFEDALKTTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJX5</accession>
    <name>A0ABR3YJX5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein that induces appearance of [PIN+] prion when overproduced</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PIN3</name>
        <name evidence="5" type="ORF">Cpir12675_006099</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000252">
        <property type="protein sequence ID" value="KAL1888610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050670">
        <property type="entry name" value="STAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45929">
        <property type="entry name" value="JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45929:SF7">
        <property type="entry name" value="LAS SEVENTEEN-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0034">Amyloid</keyword>
    <keyword evidence="5" id="KW-0640">Prion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="102"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="49"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="172"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="55"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="180"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1888610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="270" mass="28570" checksum="353CF06600741131" modified="2025-10-08" version="1">MTDRQKILETNRSIRTIKQELENLLGHGAIDESTFDSLSNLLPAEGSIRAGPSNATPTLAPAHAAASDPSPAPPAYNQTPAPEVPATRDAAPPAAPPPSGRPVLSTARALYMYVGGGDARDLAFNKDDRIDVYEHMNPDWWMGRNQRTGAEGIFPANYVLVGEQKAPIPGPGFYGQQPMYAPQPYGYHQPQQSYYPPQQPHQQQAQPGPAAPASNDANPMVAVSEGNKNEGGGGMSKLEEGGKKFGKKLGNAAIFGAGATIGSNIVNSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK70</accession>
    <name>A0ABR3YK70_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000251">
        <property type="protein sequence ID" value="KAL1888661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="481"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="547"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="661"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="556"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="691" mass="77810" checksum="BA14E07A2500434A" modified="2025-10-08" version="1">MPPAKRHGATPKPSVVSSVEATPSPRFTAECQVFLPANVKVSDAEWPVFDLREAVVMDRTRCFVRNLLRVQETGPFIVQGRVYCDTSDEAQVAQLLHPETFRPIEIEIEASSMSIGLDSFGDGDNENEPTSGPVIWAKSYYGFFRIASPALCYRATFNHTLEAITLYYYIMGVYEAREPKVERGGNMDKACTPEMALEDVFLLYAVMVGDGCVIEDVKERCMMHAAFLASHFKFETGFSWEGKAFTKYIRSLVLTSRVWEKKNLDVTSVNDDGLDDPVLKSQAYVPGLDADSSRSISPIATATELHPSNKLSSTPNSKTPTRSMRSFNSATTTKEENSGWEMEMISRTRLARAATSTPPTPEPGQIAPMSCNHQTQASENVIARKIYEELPYLIGDRKISRVSLKSLNNIVFTSYSTRSWPSAREIVAYAIKDLLRLMDSDTEQRDRWMRSKLWTDLQEAPEFEGPLTENHSVDAMMKQLRRRSGVQKGQKRPYDEERSLTSGKTSSLRPHKRSISNTGRDESALGTWDKKSVDVDLKMADEEEYDEFAIFRRNEDQEEESTDESETDSDEDEGIPPTNKLHLVIRSDPMPTTAPNGSGSMWICHVKDCQFVEADADNNQGQERIKMHIHDHNDEAARIDLALAESHGHAIHHLLEKLKNVHNSSPEDSDSETKPNPKPATPIKRRFFGFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKC1</accession>
    <name>A0ABR3YKC1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000252">
        <property type="protein sequence ID" value="KAL1888618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22584">
        <property type="entry name" value="Rcat_RBR_unk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="682"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="776"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="580"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="604"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="703"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="780"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="808"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="848"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="879"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="927" mass="100406" checksum="CCFAAF73DC804C92" modified="2025-10-08" version="1" fragment="single">KSCIDCLDDISPQQIIKLDCGDYICHYCLKQRFRDSVKNSARFPPQCCEISIPLKLISKHLDSSFKKAFDRCLAQYNKSQASSHRHLQLDKDEEDDDDFDIDARPPSVSASAPGYHGYSDPYSSTKRPSRRHNKDRVRDRDEIGSARTAPTPRREATKINGWQRCYNCDAVVEQREGSSFITCRCGAEFCTTCGTKWKDCDCHLASCGPLLNSTNSEFAGGGSEPLPDDEMAYNPQPRLNRGDRVSGRMSVGAPPGPSSEYYARTAAREAPREYHNDYNVGYGAPMKPRDRDYASERAATREPSAGLGRERMFAGRERERERAGFARDRERAAAAAVDYPDEYMDYNAEYPDEYDADYGDLPAGGSAGNMGGFRQEFRSREPSAPAAANYADPRVHPSRQTRTRPGARAATEAGYDDAYPDEYAGASAAIGGKYAASERYLDDYGQDGYAAAPARYAASAKFERPSAKYAADAYANRLPDGFEDDDYRSEPVARPPTGYNRHATADFAGDSLPEARDPRDIRRERGSRDARPSRAASRPRHSSAAQAYEEEHERPPRHISEARGNELVLGHSKAPRSHEEEIDEDSEYEEYSNAPQPPAARQRGSGGGFGRGGRATATAPEEDDDYYDDYARATHSMPPGGVSQRASVHGTVAFERHSTTGEFPKTRRRANSTERRLIGRFKNRNSVPPSPRTAPPYGGHGPHAGAPPHMSGPMPPGPMSAMMPGPGPMRVPMSGPMGVPMGVPMVHAGPMAPMGGPVPVPMVAMNAMGSMGVPGGPMNGPMPPHGHGPGPGPGPGPGPGPLALYGNRPPPHMLPPLAPGAPMMHPPFDKGMFGPGPGGPPRGDIKSPPGGRYAGRPGPLPNEYNDDAAGHAPVRRRRRYDDHHDDNVKSSTMAGLTGVGTGMARVSEWVGHIPPGATPSAPPTLMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKD6</accession>
    <name>A0ABR3YKD6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006103</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000252">
        <property type="protein sequence ID" value="KAL1888614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF37">
        <property type="entry name" value="CLAVALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="326" mass="35191" checksum="47F0855DAECD9E00" modified="2025-10-08" version="1">MSEDPTTDSSTRDLSGRYVFVTGASRGIGRELLFSFARAGAAGIAFGARSFRNGNDEIKILTEQIHAAALGGWKARQASGSDSRSAAEQPQPPLVLPLVMDVTDASSVEAAAQAVEASFPRLDVLVNNAGVLEKRATLADADVQTWLTTLDVNLNGTFLATHYFLPLLVRSKGRTWDSKAPNLGKRDAGEGDEKHSTAAGLQTIVNINSLASQMVSPGASAYQISKLAQLRLTEFVNCDHAKDGLLGWAIHPGGVATQLGLSLPVERHAALTESPRLCADSVVFLVEKRREWLAGRYIMAQWDMKELLAREQEIAEGDKLKVRIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKD7</accession>
    <name>A0ABR3YKD7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UBC core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006221</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000267">
        <property type="protein sequence ID" value="KAL1888298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23814">
        <property type="entry name" value="UEV_AKTIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBC core" evidence="2">
        <location>
            <begin position="12"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="336" mass="37186" checksum="2BFAA4100A95F3A2" modified="2025-10-08" version="1">MATLRMASLPSMRKQHLMAEFAGLKQACPDGVFVSLTPGDPSTWSGVIFVRKGPYSSAVLRFQISFPDAFPRLPPQVTFLTDMFHPLITPLSTYSNEGDTVSANDSERLPPGGFSLRHGFPSWFARRTARRIASDGRPVIATPPRNPASNPIRIVESESRRQRSDSIFGTPASQHTSSTDRPGYTRTDKEAVPVYDVLAYIRSSFDDEEVLDTIPLEAAGNQGAWHAWRLHRKESLMASGHEPAANPDESVFSADESEPRSPVSPPPALRPRQASQWNWEGVWERRVSQNLASSLQDSMLYGGTTPSDELIHFLPLEGQELETTKENLMRALGATI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLB2</accession>
    <name>A0ABR3YLB2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pre-mRNA-splicing factor cwc22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CWC22</name>
        <name evidence="8" type="ORF">Cpir12675_006081</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000250">
        <property type="protein sequence ID" value="KAL1888672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050781">
        <property type="entry name" value="CWC22_splicing_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003891">
        <property type="entry name" value="Initiation_fac_eIF4g_MI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034:SF3">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWC22 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02847">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02854">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00544">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00543">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51366">
        <property type="entry name" value="MI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MI" evidence="7">
        <location>
            <begin position="463"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="424"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="659"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="37"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="78"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="427"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="675"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="714"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="741"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="781"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="802"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="822"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="874"/>
            <end position="884"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="884" mass="100556" checksum="B57D3F0D177BDB20" modified="2025-10-08" version="1">MAPRSSSSDFKSRSPHRSKSRSRSLTTQSPHKANTTSPARSRASKSVSRSPSRGRSRSRSQPSDLPSENKRSPTVSRSRSRANTRHNARSQSPSRGPSLALHQSPKPLLATSTSEQIEKAEATKQADLKAEYHRLMDLRSGGTYIPPARLRALQAQMGQDDSDEGKRIQQKFHWEALKKAINGLINKCNVSNIKYIVPELFEENLVRGRGLFCRSLMKAQSASLGFTPVFAVLCSAVNSRLPQVGELLVSRLILQFRKAFRRNDKKVCLASTTFLAHLTNQQVVHEFLALQILLLLLNKPTDDSVEIAVGFMKEVGEFLSDMQPRPVMLVWDRFREILHEGEIDKRVQYAVEVLFQIRKDNFKDNPAVKEELDIIEEEDMITHKLSLDDEDLKSQDTLNIFKYDPNFEASEAAYKRLKAEILGEASGSDDESGDDDSDEDDSSDEDEEKKIEIQDQSNADLVNLRRTIYLTIKSSMDPEEAVHKLIRVKIPVGFEHELPSMIMECCAQEHTYQKFFGLIGERFAKLNRTWTDLFEKQFATTYETIHRFETNRLRNVARFFGHMFAFDGLGWHIFSVIHLNEDKTTSSSRIFIKILFQDIAEIIGMKKLRERLSDPQMQQYYEGIFPRDTPRNVRFSINYFTSIGMGVLTEEMREYLLNMPKPSLPAPPTGDQSDSESVSSYSSWSSRSRSRSRSVTPRKSSRGKSRSRSESYDSRSPSRSSSRSHSLSRSRSPAQRRARSYSRSVSRSRPPLVSKTRGSRRGRSITRSPEPRHQRARARRNSSSISRSPSVEPRASRRRRNSSFSRSRSCSRSVSQSSSTRSKSRSRSSIPPRRRSGNLTGAKRHASPYSRSPSPVKSKATGKRRRTPSLSRSPSPPPIKRGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLX6</accession>
    <name>A0ABR3YLX6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_006033</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000243">
        <property type="protein sequence ID" value="KAL1888806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01365">
        <property type="entry name" value="KISc_KIF1A_KIF1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47117">
        <property type="entry name" value="STAR-RELATED LIPID TRANSFER PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="3 4" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="7">
        <location>
            <begin position="43"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="534"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="444"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="542"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="148"/>
            <end position="155"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="610" mass="68589" checksum="C960D1CD54EEDF9D" modified="2025-10-08" version="1">MPMPGAVAQAGTPERRLIRSSASTPSLRSRDAPAHLRSDASGNVRVVVRVRAFLPREIERGAECLINMDPSTQETRLLAPSDRDPANARAKSRKSNSEDRVFTFDNSFWSHDPFDPHFAHQEDVYNSLGEEFLDHNFEGYHTCIFAYGQTGAGKSFTMMGKPGQSGLIPRTCEDLFERIESAQSETPNISYNVRVSYFEVYNEHVRDLLVPVVPGQPPNYLKIRESPTEGPYVKDLTDMPVRNLHEILHFMKVGDASRTTASTKMNDTSSRSHAVFTIMLKQIHHDMETDETTERSSRIRLVDLAGSERAKATEATGARLREGSNINKSLTTLGRVIAALAEPKAQRSSKSKRYHKDVVPYRDSILTWLLKDSLGGNSKTAMIACVAPSDYEETLSTLRYADQAKRIRTRAVVNQDHISTAERDAQIAAMAEEIRVLQLHVSDSRQKEKDVKVQEEKLEEYQNRVATMQRMMEEKSLVAEGKIRSLQTENEALRLHLKLALESIKNPIPDVAVGAPIMNNNDVAVALDRNLRHGQSKSGMASEDDEDYDEDDDEDYDGEDGYLSATLQDSDDETQEYIQGLLKDLSLFRRKINDDKDRFMMPESNCVSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM84</accession>
    <name>A0ABR3YM84_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005773</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000215">
        <property type="protein sequence ID" value="KAL1889465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="315"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="350" mass="38868" checksum="461956F8269BB0AC" modified="2025-10-08" version="1">MPLLYSRFLCSSSLFKISTANFNIRYDASSREDGEKRWDERDCNVKIDRYRRYCLTEQVKTTAGGISNEGAAVIGLQKASNGQLEDVLEDLGSQWKHVGVGRDDGKEKGESSPILYRPNVLELVHSEAKWLSAEPDKSSTGWGSKTSCIVTLAVFNHIATGYQFIHAKTHLDNVSSESRVNGVRAIVDHIKAIQGRYGPLDVSLTGDFNSARALEALPPGADAGFLTDSYNLASAVRFGYLGNTYIGFQSSQATSRIDYIWFGWSGTQEQPFTATRYEILDNLVDGVFISDYCLVMCDVEAKLQVGGSTLMREDYFSYILFIGIVNADFTAFIAVRIHTDIFLSFKTNLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMK3</accession>
    <name>A0ABR3YMK3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein TED1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_005748</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000213">
        <property type="protein sequence ID" value="KAL1889531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033308">
        <property type="entry name" value="PGAP5/Cdc1/Ted1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13315">
        <property type="entry name" value="METALLO PHOSPHOESTERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13315:SF1">
        <property type="entry name" value="PROTEIN TED1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="560"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="629" mass="70998" checksum="B0F7531A07D03B5E" modified="2025-10-08" version="1">MRYLSLLRGSVCLLAPIGLLSTIYLYYYPVFLRYAFPLPQAPNVASAPSPSAAFFDTLRRHSPVNLDFLGPQPPLAPFRMLTIGDPQLEGDTSIPTTWLGHMPHMFDVWDHITFATEFGSPRQRLKAVFHDIVDVFFEDLYNELLSIRKRVDLIGNDLYLAHVFRTMNWWTQPTHISVLGDLIGSQWIDDAEFKRRGVRYWNTVFKGTEKVPDEVATYPAEEYDLSGHIGKENDSSAANWTRRIINIVGNHDVGYAGDLTEERLARFEHTYGKSNYELRFEYPITDERLRKTIFDEESNPDSTRLVPELRLIIVNNMNLDTPAKSSKLQDDTYTFINDVIGTSSAVEFDGHFSVIMTHIPLLKEEGICVDSPFFDFYDEEDDSGIREQNMLSYDASKGFLEGLLGMSGDPETANKGLGRPGVILNGHDHAGCDTYHYINQTDDVPVDERRWAVRRWKNATESKIPGADGLPGVREITVRSMMGDFGGNMGLFSAWFDTEEWKWKYEYVACPLGKQHIWWAVHAIDLVVAIGILISGLDLALLKIAGFDVETRIRGTKTQMDDNVSAKAASESQGSPPSAKAAEPVISERKKTMLSPPGTPLIVDSERLRSMTPRLTPSIRKSIETPDRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPI0</accession>
    <name>A0ABR3YPI0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_005646</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFP11/STIP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000204">
        <property type="protein sequence ID" value="KAL1889781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022783">
        <property type="entry name" value="GCFC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022159">
        <property type="entry name" value="STIP/TFIP11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045211">
        <property type="entry name" value="TFP11/STIP/Ntr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23329:SF1">
        <property type="entry name" value="TUFTELIN-INTERACTING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23329">
        <property type="entry name" value="TUFTELIN-INTERACTING PROTEIN 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07842">
        <property type="entry name" value="GCFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12457">
        <property type="entry name" value="TIP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="G-patch" evidence="8">
        <location>
            <begin position="278"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="182"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="319"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="110"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="130"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="146"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="199"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="249"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="322"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1889781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="851" mass="94968" checksum="FA964E63FCD95A74" modified="2025-10-08" version="1">MYGAPKFNNAFSEVYSDSDEDDDRDSNVGESGSEFQPRKRRRMDKDRAALGIFGDDSDDEDSRRSQRWKKKTLRTQGMSFVSGGKQTRNTSNDSSADENARGSGHLNEDLDRDEDEDEDMESDGFTIDTGGLGSSTRGGLGFSDTVDIETGDQEESVPLGRTSSLRGGISFSKASLELDNEEDNLDEFETPSFAPKSFKSASNIASTAPVQARPKPTAAHKSGTKSAKFDTDMPFGKGFVPSSAYTPVLRDDLPDDSRAAPQAPKSSAFASGRKSKFGNSFAQRMMLKMGYVEGQGLGKESQGRNVIIEANLRPQGVGLGAVKEKSEKERKEERRQAQLRGEKLEDDSDEERERKATSKKSLRRSVGDSGTSTPRNKAHKAKFLTADELKKMAPGLHIPAAFAPILDMTGPEEKTLTSATGLMSTNFTSGSSELPEVAERRKLIKCAHMDLAIFSEEWNSLVDRKAWTGKQLEEMEQAMEDLTMGVQNLTEFAQIVENELLLFGGWKETVARLEKAVASGAVVDEMSDIIVAAIHPFIRDADWDPLKEPDRFAADLQPLRAVLLQNGSADDDENPHEGQYFDGDTNEAYHHHRKHASAYESLMYKVWLPKVLSAIRTWDVHDPTQMLSLVTAWKPLLPPFVYAQLIAEVVRNLDAALSEWNPRKNRKSMPPHVWLFPWLSLLPPHHLDPRGSGLVADVKRKLRALVGSWDFAKGTVPGLTAWEAVLGKEWSSLLVGHVLPCMGRFLRRHFRVDPADQAPYLPALQGILQWKDVLGRKALGEVVSTQVFPMWHEKLDEWLALDEVNLAEIADWFQWWNAEVYPKEIQSLPVVREEFEKGLARMERGLQTMRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPM6</accession>
    <name>A0ABR3YPM6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sphingosine N-acyltransferase lag1</fullName>
            <ecNumber evidence="9">2.3.1.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">lag1</name>
        <name evidence="9" type="ORF">Cpir12675_005634</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sphingosine N-acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.24" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000203">
        <property type="protein sequence ID" value="KAL1889837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050291">
        <property type="term" value="F:sphingosine N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016439">
        <property type="entry name" value="Lag1/Lac1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560:SF0">
        <property type="entry name" value="LD18904P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560">
        <property type="entry name" value="LONGEVITY ASSURANCE FACTOR 1 LAG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="279"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="354"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="8">
        <location>
            <begin position="146"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1889837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="453" mass="51608" checksum="67549C090DAB3544" modified="2025-10-08" version="1">MAAQVPATELTSEWAPNDVTNHHGPLYASRKRRAGIISRKPLKYPDGLMAQLSRAFVENQISYSFNLLALLFLADACLPKSRPYTRKFFTLSYYNGSTEKYAAGADDIYFITLCVVLFTFLRASVMQYLLTPIARMGGISRAKMQARFTEQAWLLVYYGFFWTFGMYIYYTSPYWMNMKELWTNWPDRELNGLSKLYILAQWGFWVQQVLVINIEERRKDHYQMLTHHFITIALVSSCYSYHQTRVGILILVLMDVVDLFLPLAKCLKYTGFSTLCDVMFGIFMVSWVVARHFLYMAVCWSIYADIPVLIGNSCYTGNSKSLSGPFPTPEGYSYLIQPFIKADGLVCFNDTIRWLFLAPLLMLQVITLVWFTMILRVAARVIRGAGATDSRSDEEDSDQLEKEVNASSINFGNWEKKNAKRQAGASTTTGVSLAAHSGGKELLGRIGCEKHVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPZ1</accession>
    <name>A0ABR3YPZ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">hydroxymethylglutaryl-CoA lyase</fullName>
            <ecNumber evidence="3">4.1.3.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_005573</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(3S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:24404"/>
            <dbReference type="ChEBI" id="CHEBI:13705"/>
            <dbReference type="ChEBI" id="CHEBI:43074"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="4.1.3.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate metabolism; (S)-3-hydroxy-3-methylglutaryl-CoA degradation; acetoacetate from (S)-3-hydroxy-3-methylglutaryl-CoA: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HMG-CoA lyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.4" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000198">
        <property type="protein sequence ID" value="KAL1890007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07938">
        <property type="entry name" value="DRE_TIM_HMGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043594">
        <property type="entry name" value="HMGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004283">
        <property type="entry name" value="PRK05692.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42738">
        <property type="entry name" value="HYDROXYMETHYLGLUTARYL-COA LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42738:SF7">
        <property type="entry name" value="HYDROXYMETHYLGLUTARYL-COA LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="281" mass="29893" checksum="CC4E48A10999555B" modified="2025-10-08" version="1">MAESNDLLEGILEGKVLSPDPVCYSFLVPNMRGMQNMSAILSRNKGNFCTQLEPSENTATPEIEIAIFAAASEAFSQRNLNIDIATSLSKFSEVIAEAKAIGLRVRAYISVVLGCPFTGYDVKPVAVADIARDLLEMGADEISLGDTTGMGTAPRTRELLQAMTAAGIRNEDLAMHFHDTRGQALVNTAIALEHGIRKFDSSVGGLGGCPYSPGATGNVATEDMVYFLDSVGLETGVDLEAVADIGAWITGKLGKANESTVGKAMLGERRRREEGEGAMRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ80</accession>
    <name>A0ABR3YQ80_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005576</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000198">
        <property type="protein sequence ID" value="KAL1890010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="599"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="751"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="283"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="322"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="599"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="623"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="768"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="818"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="879"/>
            <end position="890"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="899" mass="96815" checksum="71716C699585A390" modified="2025-10-08" version="1">MSFARVSSFSPLSSPPAPSFDDAFANVLNTQNSLTYDAAFEEEFLAAPLVSEQSSTIGSLEGSDLEDLPIDPSLLALVDLEGNQEAATNTTATSAEPLPSFAPLLPVSNGPGFGLGIRSEYVSLEAVIAFNDSMQGLEASSSSRGMMHEPMFGPGRHTSLAGDIPAKMAVPATDMGEVLADSGIFVGTANHQASQESTFQPQFLWNGDTSLAHTSYQSPRSDFGPEPAALNLELMHKHQNGGLQAAPTIYPALDSQPTTPACCSGPDGQFSFVPVMFPPPPTAESSPSTTPPRTSSASCARKTRSGTRGRMHATNTSRACGSPVASSATTASPSPSPSVANGQTPTNGALRRSKISDPSVQAFYAVTGNSKKDQVAPSTRKETPEVMNQLARNKTRNMARTLAQKAVENAARSRVAAEMRVAEAEVSKGEEDNTEKNVSILALSCFEGSKISGGEMTFNNGKELSEIHDLEIDLLALKREAWTSQFPEGKTNSEPEESIFHAPENPYMAMTEGDATIRSATQTIAGLSSWEGPVAFAANQPKADPRRTKLEINTERAMESSFEDHGLRLDRSQDFPRLGTPLSFVKLEEDNGHALHREAQQDVVERRREQRARGNRYWARGANRSTNASSTPASSGQVTPVPFENHTPLSLSPLPPATPLAFVEEAFPVPVAGLSPASDSASSFAFSKTTRLNPSKPHKSKPGLSPTVLKFLELEDDDWMVQFVKEIRKGRPVQNYGVEWQEWEEVMFPQANTVKPPRKPRLSTQLKEAQEQQKQQEKPKKTRAAKAPRAPWGNSRKRRSGSQLGASSRSKRSRLSEDNGENEDHEMTDEGSQSLLQAPTPIDPALMMVEMDFSSPPAAKSSPQGRKSRGQNRGGRGSRGGRRGRGRGRGRGATTAAAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQV5</accession>
    <name>A0ABR3YQV5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_005663</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000206">
        <property type="protein sequence ID" value="KAL1889759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="280"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="172"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="182"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="380" mass="42429" checksum="5E8EE410ED09E1CE" modified="2025-10-08" version="1">MDSRTSYEETYNQVTSASPSYTSSPSSYQPFTPPSDRPIEPIHIDTSYAHQHHNNGNMSFSMPPSPLPVVENHMKATHHEMAMYGAEPRYHDTRYLTHESLVPSGRQSLLPMQHNAHQYPQHQLDMGMNPFGARPYQMASMPQQPSDMGAINLMDGLMPPLSYSSASMEKSGSISSMSSGGQLTPVSPTASSGHYGSISMMQNRETPVPQTSVTAILNSSPSPPCVWEGGHRSMYLGGAQHSTGALHSMQDNCMTAHMHETGSALRNSGIEVSQVKRGRHVCNEPSCAKNFKRAEHLKRHHATAHHPNPRFKICPFCTTERRFLESRFDNYRQHIRLHTIEDKTPQSRIAFHPRALELLREIESGMKKRRGSGKKASEQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRA0</accession>
    <name>A0ABR3YRA0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">U3 small nucleolar RNA-associated protein 25</fullName>
            <shortName evidence="10">U3 snoRNA-associated protein 25</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">UTP25</name>
        <name evidence="14" type="ORF">Cpir12675_005219</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 10">Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Nucleus</location>
            <location evidence="2 10">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the UTP25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000170">
        <property type="protein sequence ID" value="KAL1890823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010678">
        <property type="entry name" value="UTP25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053939">
        <property type="entry name" value="UTP25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053940">
        <property type="entry name" value="UTP25_NTPase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12933">
        <property type="entry name" value="ORF PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12933:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 25 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06862">
        <property type="entry name" value="Utp25_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22916">
        <property type="entry name" value="UTP25_NTPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 10" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7 10" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="UTP25 NTP hydrolase-like" evidence="13">
        <location>
            <begin position="276"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="domain" description="UTP25 C-terminal" evidence="12">
        <location>
            <begin position="546"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="68"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="133"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="154"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF06862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF22916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1890823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="740" mass="82940" checksum="8F71D3496086BD79" modified="2025-10-08" version="1">MSFRGRGGGRGGGRGGGRGGGRGGGRGGGRGGGRGGSFRGRSGRGGGRGRGRGRGRGAATFTNARMADDDEDISSPGEDNSDTDMDNAESESEDEAPAAASYSALLQSLKQDASPSKRRKLNSSDAIASAGADEMDSDEDYDDEDGDERHQDIDFVDEDEDDDGDSSVDEQQFDDGDDQEDIADPFESHFCSPNETAVANKVGMVKGAQWSIKRSASKVSRVVTTYLDDGSAVPVATRISGPGVLKIKHKLQEIATTMMPTFNPAQSELAAHLFNYRDILYCQRTPQNAEGLRNLVCLHALNHVFKTRDRVIKNNQKLAQKEDTTEMEFRDQGFTRPKVLFIVPTRHSCVRLVEAIVALSGPDQQENRKRFDDTYLDKESKFGDDKPADFQDLFEGNDDDMFRIGVKFTRKTIKFFSQFYNSDILIASPLGLRMAIGSEDDTKKKIDYDFLSSIELVVMDQADGLLMQNWEHVEQIFENLNKQPRDAHGCDFSRVRNWYLEDWAKSFRQTVVLSAFNTPELAELMRTNCHNIAGKIRMQPEYTGVLQQLGVHARQTFVRFDSRSADKDPEARFEFFKSTIVPLLVKRAKDSTGTLLFIPSYLDFVRVRNFLANDESVQSLTFGTISEYTDVPEASRARSHILNGRHRVLLYTERAHHFRRYRIRGVQRVIMYAPPDNPLFYKEITGDYFARSEQDGKLVAGEGLVRVMFSKYDAFRLERIVGSSRVGKMLTERGDTFDFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRF3</accession>
    <name>A0ABR3YRF3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAS1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005203</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000169">
        <property type="protein sequence ID" value="KAL1890896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF125">
        <property type="entry name" value="FAS1 DOMAIN-CONTAINING PROTEIN YLR001C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047325882" description="FAS1 domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="29"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="172"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="457" mass="51899" checksum="B682163B53857445" modified="2025-10-08" version="1">MRYSTIPISLFALGAYASTLPVQPVIMADKSVYDVIRGLGDSIKFQQRVDKNPDVRARLQDLSNKYTVFVPNDEAFEKLPDHVKDRMFSTDSAEFLKYHIAHGDYAGAGMLALHTIPSLMHEEDIGDHLQRIRIDAGLTSTNINFYAKILGSNTDAANGAVHQIDSVLIDPPRQGKLLQHFPGDFSTTKLGLDKTRLDKWLHRQSVEGGTAFVPSNKAWEGVKDDVRNWLFSDDGLEYLRVVLEYHVVFDRTLYSDTLYLGKEEDRHHETPAHRVLRIGKRVASDEFLWYVSTAGETPECKQGPIPGETNAQIGSSCKINFPTILEKSQLDVEVSRLLGHVKIRLNDKVDVQTMDGIARDGVLHSIDEVLLPCYKNGKNHKHIDDKLLKDLELDELKKYLKEFVGHDSRKVGGHNHWMDGSMPHFKDVMEEEMGRVVEEELEDFTEHIHHILDEIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRU9</accession>
    <name>A0ABR3YRU9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Histone-lysine N-methyltransferase, H3 lysine-36 specific</fullName>
            <ecNumber evidence="4">2.1.1.359</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">SET domain-containing protein 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="primary">SET2</name>
        <name evidence="21" type="ORF">Cpir12675_005144</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Histone methyltransferase that trimethylates histone H3 'Lys-36' forming H3K36me3. Involved in transcription elongation as well as in transcription repression.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:60324"/>
            <dbReference type="Rhea" id="RHEA-COMP:9785"/>
            <dbReference type="Rhea" id="RHEA-COMP:15536"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="2.1.1.359"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.359" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000164">
        <property type="protein sequence ID" value="KAL1891018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140999">
        <property type="term" value="F:histone H3K4 trimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19172">
        <property type="entry name" value="SET_SETD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.10">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1740.100">
        <property type="entry name" value="Set2, Rpb1 interacting domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006560">
        <property type="entry name" value="AWS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025788">
        <property type="entry name" value="Set2_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050777">
        <property type="entry name" value="SET2_Histone-Lys_MeTrsfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044437">
        <property type="entry name" value="SETD2/Set2_SET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013257">
        <property type="entry name" value="SRI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038190">
        <property type="entry name" value="SRI_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035441">
        <property type="entry name" value="TFIIS/LEDGF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017923">
        <property type="entry name" value="TFIIS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22884">
        <property type="entry name" value="SET DOMAIN PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17907">
        <property type="entry name" value="AWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08711">
        <property type="entry name" value="Med26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08236">
        <property type="entry name" value="SRI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00570">
        <property type="entry name" value="AWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00508">
        <property type="entry name" value="PostSET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47676">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51215">
        <property type="entry name" value="AWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51568">
        <property type="entry name" value="SAM_MT43_SET2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 21" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0678">Repressor</keyword>
    <keyword evidence="10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="12" id="KW-0804">Transcription</keyword>
    <keyword evidence="11" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="9 21" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AWS" evidence="20">
        <location>
            <begin position="165"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="18">
        <location>
            <begin position="221"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="19">
        <location>
            <begin position="345"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="17">
        <location>
            <begin position="646"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="565"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="622"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="710"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="839"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="13"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="54"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="622"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="718"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="862"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="965"/>
            <end position="986"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAL1891018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="996" mass="110483" checksum="83B90524C19A384D" modified="2025-10-08" version="1">MRSSTKPDPPPTASTNGTTASDTVSATKTTAMPTDKEKRDKETAADKLREKSSSRNLSATPSDRGSTTPLQTSVSTPNGKATGNTSSNGTRQSGIATPTPDSSTSSSTPVPISTAKPSRKSSSKAVKREVVLFNHLPSATEEAIKSFEVIPNCQYGSKNMGNTDGDVLDCDCKPEWEKSQNNACGEDGDCINRATKCECVVGTSACGDECQNQRFQRKQYADVDVIKTEKKGYGLRARQDLQANDFIYEYIGDVINEATFRRRMIKYDKGGIKHFYFMSLTRSEFVDATVKGNLGRFCNHSCNPNCYVDKWVVGNKLRMGIFALCDIQDGEELVFNYNVDRYGAEPQVCYCGESNCVGVIGGKTQTERATKLSTAVVEALGIDDGENWDTAVAKKPRKKKSVSDDEGPYVEGLEAKNLTDDSVRKVMAVLMQCKEKWIAVKLLDRIKACNEERILHIVVRMHAYIIMKSVLVTFANDDLVVLQVLHVLDKLPRITNNKIQASNITQTIQGFVSSSNSEVADAADNLIKSWAKLKSGYRITKRQANDASYEQDGVFFDYGRNRHNDASINGSTADKEKKPPSPIIDAPKGPKNNTPQRNPLMQQTRRRMPFHGAGVNAIALPQQQQQQQQLHFQQQQPQQRQDQHVDLLPEGWHVAKDPHGNNYYYNAAGQTTWERPQIPRPISESTKTVNKAAQVQEMYKNLIEQVLREPPKRHESPAVSTPQQAEQPLSVTIEPRGSAHSSSNSSKLDWWTLLPIEKQKKYYENTIVGHVKTIADSYRNKLPRDELKRFSKDICKKIVDSDYKRGRVNDPRAPLPSRAIKSLKEHVYDFFKKAVVKYQARKRSSPPDLQQNGQDCHPPAPNSSASTLGSAPASLSATSVAHTEDTPFSAPSSPGSDGKNKRKRDGDGDGDSGVTFHEGPETASSKRLKDEIETEVDVEARAETATVPCPPPPPTEPSQAMKDQQIFREQEEALVRENEEAQRDEDAALAIEQTYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS95</accession>
    <name>A0ABR3YS95_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005213</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000170">
        <property type="protein sequence ID" value="KAL1890817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185:SF1">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="472" mass="51426" checksum="BCDF678371FDC96E" modified="2025-10-08" version="1">MLGRLGMTVDQCIRTYKSLAETAFTPKWPGLARAARSSTFSATKLESAIKQVIRANCPEPKCVAYRNTNSPTTDNCPHEDLQFNDESCTKTVISAITTANVEALLTLFTTYDPSTSLSGCGIWEVARATSAAIALFKPIKVGRDEVEFADASFGHNNPCETLIAEAKAKFPGRDMLSLSIGTGLGDVAEIKDTGKSILKALEGLAASSKATALRLRNRYSGTGKYFRFNVESGLKDVTLSDWKQTSNISSHTTNYLEENKAAIMEFVSVIIRRGVTKASTQPLELGHTTKVLGQSVELDGHRPKSLDTPNDKLFTHAGFQQIALVGLGGMGKTQVALKLAYMAKKHKPDYSVFWITAASMARFDDACKKLVEELNISKTNDEYPKIIVKHYMESRKAGNGFLSLITLMKLISLVAWQIIKMKTSIIGLETMSSQELTTILGRGVEDLDDQASINGLLEELCYLPLAAAQAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSB1</accession>
    <name>A0ABR3YSB1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Disintegrin and metalloproteinase domain-containing protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Cpir12675_005036</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000158">
        <property type="protein sequence ID" value="KAL1891246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04271">
        <property type="entry name" value="ZnMc_ADAM_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1620.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.70.10">
        <property type="entry name" value="Disintegrin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006586">
        <property type="entry name" value="ADAM_Cys-rich"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041645">
        <property type="entry name" value="ADAMTS_CR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001762">
        <property type="entry name" value="Disintegrin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036436">
        <property type="entry name" value="Disintegrin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001590">
        <property type="entry name" value="Peptidase_M12B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034028">
        <property type="entry name" value="ZnMc_ADAM_fungal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905">
        <property type="entry name" value="ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905:SF159">
        <property type="entry name" value="ADAM METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17771">
        <property type="entry name" value="ADAMTS_CR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00200">
        <property type="entry name" value="Disintegrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13688">
        <property type="entry name" value="Reprolysin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00608">
        <property type="entry name" value="ACR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00050">
        <property type="entry name" value="DISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57552">
        <property type="entry name" value="Blood coagulation inhibitor (disintegrin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50215">
        <property type="entry name" value="ADAM_MEPRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50214">
        <property type="entry name" value="DISINTEGRIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 8" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046820065" description="Disintegrin and metalloproteinase domain-containing protein B" evidence="10">
        <location>
            <begin position="23"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="703"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12B" evidence="12">
        <location>
            <begin position="271"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="Disintegrin" evidence="11">
        <location>
            <begin position="510"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="424"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="423"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="427"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="433"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1891246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="780" mass="84440" checksum="1C202F8F4E248DC7" modified="2025-10-08" version="1">MVSCNLFKIAVAGLALLHSTFAHSVDRNPIRNVYVLEDPSIGTPSRHIHAYSYFDLNFVVNKQRVRLALEPNHDILHETLHITHLGQDGQISHTEPIERTDFKVFKGHAFIQHKGSSLWTQAGWARITFHRDGKDPIFEGAFRIDGDHHHIHSLKDYRRTKLDLDPDAEIGSQDPKDVMVLWKDSSIIADASGHELRRDLSANGCGADALRRNSEFDPLSNDNYHEETSLHSLSARFLFGRQMDNGQTGNNGAGVNLVDSIGSTTGCFSSRRVALIGIATDCTYRQQFEKESDMRTNIIRQINSVSAIYESTFNISLGIQNLTVTESSCPATTNPSVPWNVPCSSSVDISTRLNLFSAWRGRSIDTNAFWSLLTACNTSTAVGLAWLGQVCLSGSTSNGGSNETVASTNVIVRTSTEWQVMAHEIGHTFGAVHDCTVDACAQNLDETSRCCPLSSSTCDADGAYIMSPSTGNGITAFSPCSIGNICSAIGRSSVKTDCLTNNRNVETITGAQCGNGIVETGEDCDCGGETDCGGNSCCDPKTCRFTTNSECDPSNEDCCTDDCRLASSGTVCRSSTGPCDPEEVCNGTIATCPSNVFSDDGTSCGTNLRCASGQCTSRNQQCKAMMGSSTNTNNNDTRPCGQSNSCQMQCTSPNLRSGVCVEFAQTYLDGTPCGSGGLCRNGACNGQSMTRELRNFFQRNKHILIPVIASVGGLIVLMFIWSLCTSIRRRRRIASSRSMAKNHAHSMPMSQMAIHSYPAPMAYSSSGPVVSQYMPAERYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSK7</accession>
    <name>A0ABR3YSK7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000157">
        <property type="protein sequence ID" value="KAL1891338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="504"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="524"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="716" mass="79207" checksum="D248013DC22D5F77" modified="2025-10-08" version="1">MASSREALLFYALWRDQDVRERLFLLLSKSDICKVRLANSACCNVITKRLFKRTHITFAANTFTKPYRIQALSRVGHHIEHLTFYFPHSKYTFMAPLIHPQTGQEVSFLYTPHTSMLSCMARPKYNDNELGSILIQQYPPLFHAATNVPSFINAMKFIPNMRHLTISCPGQDPQERYRRNMVDYALISLRISIEKVRLPKLHKLSLSSVHPAAFIYLRHAPGIGSGPSSTRRWSQINNLRVTVDSWDFCGPAPGFDHLKMLQDYVRGFAPNLEKFKFSWAGDFKGPCPLVLPIGSHMLPGEDLGNKSPYALALECVAFRLPRLRYMEIRNAEMSAAHIRGIVRAHKHTVKEVDFDNVTFTDDGSWDEAMGTLYYDRSSGSHLIRSLNMGSIVPDLSLRSPSVAVQAASRRLMQATMGFARSFNVEDDGDLAESRSPKMRPCDNDALFIAGLTDKELPSIPPSPAKSSKCQRFLGELSPRRDKTKGLTFGQQIITYASDAPAPLFQDGSFKRSKKSPEPRFHFPLTPPRTPKSPQTPKPKGHGSPLVRSASVNTGLGASAPQVMTPALEVSPVQRNFAQEAAHQKLAADSVMRTQALQRAREVVLQRMAREYQPPLSTRGESPVGGAGEHGYGYDFGPSSPRTAVSGNAYEHPVAIGASGPPSVLPLDVAVGGCMADITTGRKFRQALFGPSTISILSDCGVIESQSALVPLMLSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT63</accession>
    <name>A0ABR3YT63_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ADP-ribosylation factor protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ARL3</name>
        <name evidence="3" type="ORF">Cpir12675_005085</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000161">
        <property type="protein sequence ID" value="KAL1891149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45909">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45909:SF1">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="240" mass="26768" checksum="30AA7D1F7196424F" modified="2025-10-08" version="1">MYHLAKGLYMMATSKEEYSVILLGLDNAGKTTFHEQVKSLFMPDRPAPRLKTVPTVGQNVSTIELPDMYLKLWDVGGQMSLRKLWQSYYASCHAIVFIIDSTDIGNGSLDDDVDHDADDLNVGVASNPHTRVSRGATEDVADGRLDECRLVLEDVLQHSDTEGVPLLVLANKQDREDCVEVVRIKEGLVKKVFEGEKADSIRDSRVLPISALTGTGVTEAVEWVRSRVKWNKESRPPVMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTD2</accession>
    <name>A0ABR3YTD2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatidylinositol 4-kinase</fullName>
            <ecNumber evidence="7">2.7.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">lsb6</name>
        <name evidence="10" type="ORF">Cpir12675_005041</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19877"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
            <dbReference type="ChEBI" id="CHEBI:58178"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.67"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="7">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Vacuole membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PI3/PI4-kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.67" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000159">
        <property type="protein sequence ID" value="KAL1891224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004430">
        <property type="term" value="F:1-phosphatidylinositol 4-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039756">
        <property type="entry name" value="Lsb6/PI4K2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12865:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE TYPE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12865">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE TYPE-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="9">
        <location>
            <begin position="161"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="312"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="404"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="599"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="63"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="317"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="337"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="404"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="415"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="441"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="653"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="694"/>
            <end position="712"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="788" mass="89325" checksum="251F2241626B18FA" modified="2025-10-08" version="1">MPPRQTTTGYERLAQADQHSDSEEEDFLAQSFASLQHGTTTNRYTSQPAPRGAASNVTSPRRGAARLHPHRRHGSGGAGVDLKAMNARLERWADEIAARFKGSHRNRPGEERRLEIHHSVFQAPEGVVPITPDKLAEVQPVMKQDEFEVIVNSVRRAIDRNVHPLMISQGSSGSYFARNSDGKVVGVFKPKDEEPYAAGNPKWNKWIHRNLFPCFFGRACLIPNLSYVSEAAAYTLDCQLRTHMVPYTDVVYLSSKSFHYPFWDRHSFYRKKKPLPEKPGSFQVFLKGFKDANIFLRENPWPDQYWSGFRTRDGTRRSQTPRWTDSCRPSGSRQLEEQAESQDIDPESQPLGPDNFRWTDALKQSFREELEKLVILDYIMRNTDRGLDNWMVKVDWSTQQVSIQSEPMNFNITSDSEDDNEDEDGNEATPGPRPADPSRIKNPSVQRASNPYKAQNPMEADATPTATHKITIGAIDNSLSWPWKHPDAWRSFPFGWLFLPVDLIGRPFSQKTRDHFLPLLTSTHWWSQTQYALRKVFQMDEDFQERMFAKQMAVMKGQAWNVVETLKTLDHGPLELTRRAKVCVWDDLVDVPVAVPMRSTSSEIHRRQKSAGLDDFDISGAHPEPDLLGLGSPSEMPNPGRFELATSPPPSTSSPRPDQQQQQQQQSTVPNYTRYGPQPYQTRLNMYSPDRHGSSSTAPLPPASTAAPPASARANSHQRRYSYATAATRKTTNSIAHQLYGGLDGYEDDDIEGDLGYAAAQGMEGQMRKVIVERLEPVKSRNPVFTWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTK0</accession>
    <name>A0ABR3YTK0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SUZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000156">
        <property type="protein sequence ID" value="KAL1891350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024771">
        <property type="entry name" value="SUZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12752">
        <property type="entry name" value="SUZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51673">
        <property type="entry name" value="SUZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SUZ" evidence="2">
        <location>
            <begin position="96"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="139"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="251"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="348" mass="35813" checksum="1ECD57D77E5125A7" modified="2025-10-08" version="1">MTSSQAVPNAWDDDDWSKAADSLTNQTQACTLGFASSTVKPKLSRAQQEALHREENRRIWEAADAAQPFSFLDASKTGIAPPETFRQVRVLSRKPPTPTSRTPQSPVPGSGSDSGMRNDLSTSMPGSVLARPSGPTSVSPSALAAPSATASDSDEDDADDSICKPVLSLHERMAKQAREREEKQRRYDEARAKIFGAPASTQASTGSVSSAASGAVNSNSSGIGPTNGGLNAGLSGSLPRGRGGRGKTSRGRGNSSNNINSYGPGSFEDTQSSSSTRGSRRRPARTPGSIPPGMGTNGGNSTARDEPVHAIRAPRNPPEPGSRGGFAAGNRGGRGRGGAVAGGGVSLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTR1</accession>
    <name>A0ABR3YTR1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cyclin-dependent kinase</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_004944</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000153">
        <property type="protein sequence ID" value="KAL1891467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF107">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 11A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="117"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="427"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="20"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="436"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1891467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="460" mass="51435" checksum="0628F4AF579A8862" modified="2025-10-08" version="1">MSTKPSSRWADTPEDIAHEARRKKEKAEKRRQKAEKSRLEAAARAQTKLEDYSASTTSNPEPSLDDTRSTKRQRITAPQDNDSFQTEPEDPGNDSAITMLRFEGRSFGPPSSLYQGFSKLNNIAEGTYGRVWRAECKQTGNVFAVKQLKSEDSGNKKVLPLTGLREIQILRDCDHRNIVKIIDVIVKNTTPPIETVSLVLDFIEHDIRTLLSSMPEPFLGSEVKTLLHQLVSGVAYLHDHWILHRDLKTSNLLLTNRGVLKIADFGMARYVGDPPPADLTQVVVTLWYRAPELLLGATSYDGAVDMWSIGCIFAELMTRTPLLQGSVEADQWSKIMGFCGPLNDQTWPGFGRLPLAQAMKASKYQSRENKHSANTAESIDKLLPQIAPGGKSLMQALLSLNPTSRPRAKQVLGSEYFSELPKAKQEHLFPTFPSKARQEARTWDEPRAPTRGKNLLEGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUY9</accession>
    <name>A0ABR3YUY9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongator complex protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_004691</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ELP5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000138">
        <property type="protein sequence ID" value="KAL1892141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19496">
        <property type="entry name" value="Elp5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019519">
        <property type="entry name" value="Elp5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15641">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15641:SF1">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10483">
        <property type="entry name" value="Elong_Iki1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="294"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1892141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="365" mass="39292" checksum="77764602FEC7A244" modified="2025-10-08" version="1">MAPSAKDHHRSKSLLLLQKLLNLRDGASPLTLVVDSLEQTAGPVLREFAARAKISQAKVIFVSFTTLKKPPYAHAFVPAWGCQFTTLQPRILAHCPAINKAAVKAKTQQRAIIIVDSLNAMINNDAAAAVAFLSSLITPTASLVGVYHSDAPTRMPLAHCEYAPQPIAVLTHLATAILRLRPLAQEVACAAARDRALVEPEFGLREGKEGVLLGLRDYASAGVAVVGSGQATVSGSPTPTGCAVGTVMEMELRRKSGRQVSETFVLCPRDAKDPRASSGLGMLVLRDEHPLLVRRGASENEDETNGDEVPQSTFSMGLTDKQKRDRSDIVLPYFDAQIDVGGGEGGRILYDMGREDDFDEEEDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV18</accession>
    <name>A0ABR3YV18_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA polymerase-associated protein rtf1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RTF1</name>
        <name evidence="3" type="ORF">Cpir12675_004639</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000136">
        <property type="protein sequence ID" value="KAL1892171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.200">
        <property type="entry name" value="Plus-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004343">
        <property type="entry name" value="Plus-3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036128">
        <property type="entry name" value="Plus3-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03126">
        <property type="entry name" value="Plus-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00719">
        <property type="entry name" value="Plus3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159042">
        <property type="entry name" value="Plus3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51360">
        <property type="entry name" value="PLUS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plus3" evidence="2">
        <location>
            <begin position="267"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="549"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="616" mass="68607" checksum="FF0428A7A24D4ACC" modified="2025-10-08" version="1">MADIDDELLALAGGGSDGEDNSPRSPSPESSASGRKRRRSRSRSRSPARRARRDDSEEEEGEARSSAPGSPDSQQSVPMDESDSDAEPAPSKSFSRDAIGVDEEYPIESLYRSHAEKAEISRMVEVERETILAERREHMERFKQNRVLRQLVSQRESGDRGGSGPGSATGKRSKRSAGDADLDDSDSDSGADTRPRGRSSRSKASDKMDDYRRARAEKVDRMRRLKEDRERARDSNSSRNYDAYDDDNEGDSWHRRSPTPEVKSRRQPELNDFERLLISRAGFAQICFKPQFEESVIDCYVRVLGKPDRNTGEQQYHMLSIKGITAGKPYAMQDARGSNSFVTEQYVVAGLGKRTETYPFVAISSGKLTESELQKHKDALANMGLNTPRMALLEDRLATLNKLVKYELNNKEITEMVERKNQLRRRVDPAQREALQRSIAEAEDAGNMIMARQLQEDLDALGSSTGLAFRTSLNPKASSSPGAHRIQQDKMTELNRLNRKKNVEAVRRAQLKERQHIRDLEAAAARGEVVQEDLSRRLKTKAKFVHDVNDGGLGGNPKAGGTETAKDAATAASDRLSRPVLQIAQAVSNGIPTVHRPVQEDDIIAGLDMDIDVEID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWM5</accession>
    <name>A0ABR3YWM5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000137">
        <property type="protein sequence ID" value="KAL1892153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047364977" evidence="1">
        <location>
            <begin position="17"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="208" mass="22920" checksum="796312DAE3442504" modified="2025-10-08" version="1">MKFLLFLTFCCTIVFGAIIPSLAPDLKPSTAMADDPTGPPRVHKLLSRDSSAAYKEAKRAAKEEGVTLENGEYYYFMSCNTARAGFTPSEPAVRYVLEQTGCTHVALVVGKITRTRWTKKFEATYLNVSDSPSGTAWKQLVNDYNPRSNQKLIYGGQAVSSPSISALRIAGNDWLEQANVGGPNGGRQYSESMNCLNYYYDLRDMVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYZ9</accession>
    <name>A0ABR3YYZ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004304</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000118">
        <property type="protein sequence ID" value="KAL1893070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF10">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="22"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="659" mass="73290" checksum="9C3141DE1B87FD4B" modified="2025-10-08" version="1">MRLLHTLTLRLSEFPQSSIPEYAILSHVRGSDEPSLHSIVSATAHTHRGYRKIQGACRQAQHDGYEWIWIDTVCIDQTSSSEVSEAVNSVYLWYEEAAVCYVYLADVPRFYFGDSQWFERGWTLIELIAPRDVEFYAADWTEIGTKNSLETELCHITGIRAEVLRGTASPATCSVAERLSWAARRCTTKLEDEAYCLMGLFGINMPVVYGEGRKAWTRLQELILQSTEDLSLLAWSPNIYSSADDAKVSENYSGCLSPGPFSFGRPDLATFLPSTTFGFDDTDSIMYPDVTALEWRHVQRHISHSSSSKSSQFAYDSPVINNRGIELTLLVDPLAAETSAGDSKTVDDAIETEVLAWLYTDVVISGNLSPIPMSDSSSTMARRTMMVCVWMTVYRPSRSWSGKLWARRTPGKSPVAVPLMSRGRFQPKKMFLQRSANKLQSTSSWKTSEPCDSLSFVDESILLSDATRSLNIRMMSDMDTTPLRIVSHYPASAKLKHPQPAKSLDGCLANIPVTDFRAMTDTGHQVNASGALKFFLMGSDPAEDAQFVVIFGQREDSGNVFCHVEQTDMPQDTGERPFRRAWSPDLKGGSISGVAAGVHDELTDRSMLLLDCGTAVVAMVKKRRDGRFGKYVPTLVVACHKDGRKFFDAAGRESECSID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZH6</accession>
    <name>A0ABR3YZH6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Vacuolar protein sorting/targeting protein 10</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Carboxypeptidase Y receptor</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13 15">Sortilin VPS10</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16 17">Vacuolar carboxypeptidase Sorting receptor VPS10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="primary">VPS10</name>
        <name evidence="22" type="ORF">Cpir12675_004073</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Prevacuolar compartment membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000108">
        <property type="protein sequence ID" value="KAL1893465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.70.80">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031777">
        <property type="entry name" value="Sortilin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031778">
        <property type="entry name" value="Sortilin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006581">
        <property type="entry name" value="VPS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050310">
        <property type="entry name" value="VPS10-sortilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12106">
        <property type="entry name" value="SORTILIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12106:SF27">
        <property type="entry name" value="SORTILIN-RELATED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15902">
        <property type="entry name" value="Sortilin-Vps10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15901">
        <property type="entry name" value="Sortilin_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00602">
        <property type="entry name" value="VPS10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110296">
        <property type="entry name" value="Oligoxyloglucan reducing end-specific cellobiohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="20" id="KW-0732">Signal</keyword>
    <keyword evidence="5 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="20">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047483453" description="Vacuolar protein sorting/targeting protein 10" evidence="20">
        <location>
            <begin position="30"/>
            <end position="1529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1397"/>
            <end position="1417"/>
        </location>
    </feature>
    <feature type="domain" description="VPS10" evidence="21">
        <location>
            <begin position="56"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="domain" description="VPS10" evidence="21">
        <location>
            <begin position="748"/>
            <end position="1386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="663"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1484"/>
            <end position="1529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="668"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="1513"/>
            <end position="1529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00031354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00031902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00032705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00032910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="SMART" id="SM00602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAL1893465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1529" mass="171096" checksum="A307705807162F8A" modified="2025-10-08" version="1">MRLGQSSLAWAIVSQLLAASVVLPGFAAAKSDSPTVHTSTFSAPPENINYFKGSNTLLFHDVEAKNIYKSSDGGDTWTQLTDVPDGIAYMLIMHKFHKDRAFIISGEREHWQTFDKGQTWSKFDSGAKTSGMRPGILHFHASDPDRIIFDGMKCESIFCDDVAMYTTNSFKDIAAPLRVDNSGCWWAKSTPEFTTGSDELDAKRIMCVVRDFFSPFKEDQRLFYSDNFFETHGDTTVEETEIKLHDGKDVVGVVNLAMIKKFILAATASVGTDEMGLYVSDDSVNWHRAMFPTSHNHRVNQEAYTILESTNYSIQVDIMTTRPSNPMGVLFTSNSNGTYFTENSEHTNRNIRGNVDFTKVGSIEGVYVINTVENWEEVEKEIDVSKNLITSISFDDGRTFEKLVNGNEKINLHLITDSNKNAPEFSNSALGVFLANGNIGTYLSDIKDSNLFASADSGATWNKALSGPHMWAFGDQGSVLIAVDESNAEDVSEFSYSLNYGETWKQVKLPNDIKMQPQTLFGARDSSTLKFILKGHSDAHSKYHVISIDFESLLDRTCDENDMEDWHARPDKDGKPTCIMGAKQTYRRRKKDADCFVRKPFSITSPSTEACDCTDADFECDYNFVREDGKCVMAGQIIAPDGVCKDRQPDAVFKGSSGWRLIPGNQCKRPEGSQKDDLVDRKCKDSTDITIPSDDDNKDDKGNNSGPINNDRFVFDTQLKSFDKLYLERGESSSQDDETVIVRPYGLDNGEIIVEDKVWLTTDQGKTWTRILKDYMVHGIFPHSVFKDVVFMTASAHSSTDTVNKVIYTIDRGLNWHEFDLPHPPISGKPFSFHPDKKDWIIFVGEVCEEVNGNCMNEAFLSVDRGDHWKTIGRQVHRCEFTGHSAYKYRNQKQIVCLSRESEDDSPLRLVVSNDFFSEDIQYPKLTDKNGADIIVRQFATMSEFIVVAAEVPRTLGHLLAFASIDGENYAQAHFPFNFNPEHSNEYTVLDSSTHAVNLFVATSINEGHERGNIIKSNSNGTSYVLSLADVNCNMNFFVDYEKIPSVEGLAIANIVANPNKPKEEKKVRTKVTHNDGAEWMYMAPPAKDVDGKSFGCNANTGTEKCALHLHHYTERADKRRGFSVPTAPGILFGIGNVGSYLEGLDKADTYMSSDGGISWRQVRKGIWTYEFGDQGSLLVLIQMDDKIKTNTLLYSNDEGATWTEHQFQEEEAVVTDITTLRSGTSRSFLIWTINSEDQVASTRADFSGLAIHGACTDDDYDVWRPRHPMLNNDCLFGHVSQYLRKKPGRKCFNDQQARRTLESLDCKCTRRDFECDYNFEMDKHGQCSLVPGREPQSAQDYCSENPDAVAFYKPSGYRRIPLTTCVGGEEYDKVNTPIACPGHEEEFKKVRSTSGVVLFFAIIISIGLAVAAGAWVQRNWHRKFGQIRLGEIAYDDDDDEYGLGAPWVRYPVMAISATVAVLATLPMTVQSLWRSATSAYQQISGGSSSDGLNAPRFTTRDSFSRGAPDYGIADDDEGELFGDDSDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZL6</accession>
    <name>A0ABR3YZL6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_003986</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000104">
        <property type="protein sequence ID" value="KAL1893688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008253">
        <property type="entry name" value="Marvel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01284">
        <property type="entry name" value="MARVEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="MARVEL" evidence="6">
        <location>
            <begin position="17"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1893688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="173" mass="19313" checksum="7C0733824105ED18" modified="2025-10-08" version="1">MIEVTRFKLFMCGLTLCLIIELGLAWGLIGILGPGANTPNFMLFSTIWTIVLLLYIYLSQKYLPQVFNRRVAFYALALTVIFWFSGSTALAAWVGIPDTTNNMERVAQGATAFGYFIWGMLCIMLWLDWNALLKKRINTAAFISKETSLGTAISSSDYTYRQPSYSEVASSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z063</accession>
    <name>A0ABR3Z063_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Cpir12675_004083</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000108">
        <property type="protein sequence ID" value="KAL1893475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF400">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CBK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="222"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="20"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="82"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1893475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="417" mass="47375" checksum="F8370A8D1518807F" modified="2025-10-08" version="1">MKSLGRNHDPSRDTQIGVARTNSVKNRPTPTTHLQQVLQGRGDNLQQPARPSDIPEEQDNVSPGEEKETSEPIVTVRPVESGTVNRARQTTLSSRPRKRQSAQFIDSSQIPFSRSSTSSRSTRQLIRVVPTIETVERVAAAKVYLESYFNSIKDHIDSREKYRLYMENELDVAGSLTTEQKALMRMLFNQEWAWHLRETRFLKARSSKATRGLAISPVIDDYEQIRILGKGSFGVVKLVREKGPLGHRNQVYAMKVIRKANMLVYGQEGNLRAERDLLIAAQASNWIVPLVASFQDASNLYLVMEYMSGGDFLGLLERVGSLSEPTTRFYIAEMIVCIEEAHKLKCIHRDIKPDNFLISASGHLKISDFGLAFDGHWSHDGAYYSAHRYSVLDRIGMEPQDEQISSMNDEAYHRHRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0D7</accession>
    <name>A0ABR3Z0D7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_003818</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000097">
        <property type="protein sequence ID" value="KAL1894083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1894083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="189" mass="21363" checksum="0FB96C553B426CFC" modified="2025-10-08" version="1">MASFIDTFMPSNTYNTLPLTSQVSGAPTDHSQDLQDLRELLNKHNAPKGVSVRLINKHFDTTEGEVMVFDKIPIPRHGVVQIMKPIAYEYGNYEVPEMSGFESFLAEFCSLVSARGLQRKFGLKLQREDDTDQTGWTEYELYAKRGTIIFPDGMPMPDGDSDYSVTTEWKAIFNELPKHVSILRHVATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0N6</accession>
    <name>A0ABR3Z0N6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Aquaporin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">AQY1</name>
        <name evidence="9" type="ORF">Cpir12675_003847</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000098">
        <property type="protein sequence ID" value="KAL1894063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034294">
        <property type="entry name" value="Aquaporin_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139">
        <property type="entry name" value="AQUAPORIN TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139:SF199">
        <property type="entry name" value="MIP17260P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="94"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="278"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="301" mass="32216" checksum="9E9421483BF66118" modified="2025-10-08" version="1">MPAAPTARRSGLSDPIRNELVAAIAEFCGTFMFLFMAFCGTQNALNSSTNSPGANDTPNVPTLFYISSCFGVSLAVNVWVFYRLSGGMFNPAVSFALALIGAITPLRCVIVMVVQIVAGIAAAGMADALVDGPLRVTNTLGAGTSITRGLFLEMFLTSQLVIVVYFLAVEKHKATFLAPIGVGMSVFMAHMVGVYLTGCSINPARAFGPAVIDKFPGYHWIYWLGPFMGALLAFVVYKLLVVLEYGTANPGQDGYNWEINSLQEQWLIHNNHVQHKVGPPTSSDGAAPRPMAGNHMGMQDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0R0</accession>
    <name>A0ABR3Z0R0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004002</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000105">
        <property type="protein sequence ID" value="KAL1893655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053175">
        <property type="entry name" value="DHMBA_Reg_Transcription_Factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791:SF1">
        <property type="entry name" value="TRANSCRIPTION FACTOR, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="358" mass="40671" checksum="593C35BAB8C26A06" modified="2025-10-08" version="1">MMLARAYLVNRKMLQPSKTEEIRLRGLCLASVRNALAQPEVAVKDSTIIAVWLMGTHEVLQGTIKWPPDKDTSWCIQQMGLVSLITARGIDQFRTAQGRHIFWLCVESIQIYQNATSQPCSSSLLAWLHRLKRWKLNKSDNVALAGAFLSARVSELYPRMLEVIFSDDPDFAAAAIPSLVSEMDAIEEDYIVCDKLAMDPELLPRARTQYKLPVCRMKLHNFLVYCINLALQANDFSTSLPEQELRSRRHRSMMLIQDISEKLLETAPPTAMYQGSKQALGREWTKTMAMMYPFASICHMKTPRHEQRIRARDVLKFIGQKCGILQALRPSMGTRMPERASRGMPNETVVGEDGIQLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0S2</accession>
    <name>A0ABR3Z0S2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable transporter MCH1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_003873</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000099">
        <property type="protein sequence ID" value="KAL1893897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17354">
        <property type="entry name" value="MFS_Mch1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576:SF45">
        <property type="entry name" value="TRANSPORTER MCH1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576">
        <property type="entry name" value="UNCHARACTERIZED NODULIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="147"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="435"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="464"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="499"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="560"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1893897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="591" mass="62946" checksum="2F72120F7D6CB43F" modified="2025-10-08" version="1">MAPSSSPLPPLMAYRSEPAPLPSPTPSTCSTASIHARTRMMSFVAAVLTSLCAGSITVFSLYGHIFQERLRYTQLQVNGVAIGSSVALYLPVSILGYVCDRYGTVPLSLFSALLFGTGYGLAATVYRHVETMAHMTTSGSQGADIPAWSYGLMVFAFVCIGVGTSAMYLSAVATCAKNFGKGKHRGLALSSPIAGFGLSGIWLSQVGSRFFSTVPQGIMLPPELDVYHYFIFLGILLTATGVAGAFTLRIVDEDDLIEEAADELGRSGFLEPPLLSRTESTMDYGTVYCSIESTDYQGTTDVAEEISLIMPPSYAMAKKDWLLNAETKSFLQDRTMWLFALGFLFMVGPGEAFINNLGTVISSLNSHGAVLPSSTFRPTSPATHVSILSITSTASRLITGSLTDLLAPSPATQHVQLDGTAISRASRNRPAVSRVIFLLTFAAMLSLGLLALASGAIQDHGERFWIVSALVGAGYGAVFSLTPIIITIIWGVENFATNWGIVAMLPALGSTFWGLVYSAVYQAGADSEFSGGRDVLDGVTSQAEEKPIFCYGAQCYASTFWGMTVTVWVACGLILIAWKGRGGWATRGIVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1D8</accession>
    <name>A0ABR3Z1D8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein AF-9 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">YAF9</name>
        <name evidence="9" type="ORF">Cpir12675_003933</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000101">
        <property type="protein sequence ID" value="KAL1893865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16908">
        <property type="entry name" value="YEATS_Yaf9_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1970">
        <property type="entry name" value="YEATS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038704">
        <property type="entry name" value="YEAST_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005033">
        <property type="entry name" value="YEATS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055129">
        <property type="entry name" value="YEATS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47573">
        <property type="entry name" value="PROTEIN AF-9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47573:SF1">
        <property type="entry name" value="PROTEIN AF-9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03366">
        <property type="entry name" value="YEATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51037">
        <property type="entry name" value="YEATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="YEATS" evidence="8">
        <location>
            <begin position="10"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="305"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="267"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="325" mass="35292" checksum="258CD20CB91F86E0" modified="2025-10-08" version="1">MAPQTQLGKRMKGVQVHRPFIYGTTAKPFDDKHNPKPPGVPDDHTHSWQVFIKGIDDTDITYWLRRVQFKLHESIPNHVRMVEGEPGKPFVVNETGWGEFEITLKLYYVAESGEKPQTLYHHLRLHPYGRTEEEKEAMRVPNGEVKAWIYEEQLFNEPYESFYDHITQGAHPKGFAGGAAAAIALTQSSGASGTAGSASGAFTPTTVTKGKGKTKAAVAAAAAVATMPPLPNPHSGAVWERSALLPVAIKSRAPFSREAEKLEMTRLEAAALKATALTKKMQEELRQKEAALAKLKEENAKAALVAKSKGAGSGKTASAGKTGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1I6</accession>
    <name>A0ABR3Z1I6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Type 2 glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">GT2</name>
        <name evidence="9" type="ORF">Cpir12675_003841</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000098">
        <property type="protein sequence ID" value="KAL1894057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06434">
        <property type="entry name" value="GT2_HAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052427">
        <property type="entry name" value="Glycosyltrans_GT2/GT47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47844:SF1">
        <property type="entry name" value="EXOSTOSIN-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47844">
        <property type="entry name" value="SYNTHASE CPS1, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G02500)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13641">
        <property type="entry name" value="Glyco_tranf_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="323"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="358"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="388"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="475" mass="55295" checksum="9C5244C1ADB3F93A" modified="2025-10-08" version="1">MRYAGLLNSLVELEFYNSTRFWVYFFWAIWLHRYVRLIVHCISHWCYKSYPLPEKPKLTSQDVTIIVPTIHTNFEELRPSLQSILNTNPATLMLVTTTPKQADLLKLARSFNHPDVQVLATPIANKRLQVCEALPQVKTDIIVMADDDVTWPYETLSWLLAPFDHDERIGGVGTCQRVRRLERGTWSERCWNWLGAAYIERRNFEISATHNIDGGTSCMSGRTGAYRKEILSSTDFLEAFKTERWGKYTLNADDDNFVTRWLVSNRWKTWIQYEDACQIETTLENNQKFLFQCSRWARSNWRSNWTSLTQERHVITQQPWCTYALHIATFTSLAFVVDPLLVWSCWRATQDWEDRRDRLLATWALVIFMFGFTKVVKLIGLFRRDYSSIVFLPLSIAFGYFHGLIKLYALFTLKMTSWGSRADGDQNDDARLTANPRRAPLLLTPGGTTLARWRSDSEKPKDLCERSSSVALFAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1K2</accession>
    <name>A0ABR3Z1K2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003616</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000089">
        <property type="protein sequence ID" value="KAL1894490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="138"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="170"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="222"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="246"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="369" mass="37807" checksum="F15A93C267D74860" modified="2025-10-08" version="1">MTPTPTQSSTPAQSTSAAPSAPSYASAAGSSKKTPSNNPAPASSASSTAHHQHAKSASISANGRLPITPALPTVQGLNGAFTSGEHSRKNSVTIGANGSSSSAAYPGNVKPASSNSHSQKSSIKFGNFDSPVMSQNTPSKQAGSGSASQQQQQQQLQPSHSSPAPPSPIPIAGAIPISSGGRPPSVVQTGMTFGSLGNDDRARQNQPVPTQPGSHGRRESSHSAAGSDMSSQNQHRSGNSYHGRGRSFNNSGSGSFSGSHHNNQMGYPPGNYRGNSGHGNRGGMPFQPGSHSHGPNQNRPPMHSTSSPQPGRSPHLSNSAMSTPNMPPASLAQPMPAQTPPHQYYSQPSMGGGMQPVNKPSLHPFTEFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1M1</accession>
    <name>A0ABR3Z1M1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">40S ribosomal protein S20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPS20</name>
        <name evidence="5" type="ORF">Cpir12675_003630</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000089">
        <property type="protein sequence ID" value="KAL1894504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="entry name" value="Ribosomal protein S10 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_uS10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_uS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018268">
        <property type="entry name" value="Ribosomal_uS10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_uS10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_uS10_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005729">
        <property type="entry name" value="Ribosomal_uS10_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01046">
        <property type="entry name" value="uS10_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S10 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00971">
        <property type="entry name" value="RIBOSOMALS10"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="Ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00361">
        <property type="entry name" value="RIBOSOMAL_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS10" evidence="4">
        <location>
            <begin position="20"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1894504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="116" mass="13141" checksum="2DB7F04097E23B0D" modified="2025-10-08" version="1">MSYQKGEKDFSEGPKAHKIRITLSSRKVESLERVCKELIERARSKDLPVKGPVRLPTKNLTITTRKTPCGEGSKTWDRFEMRIHKRLIDLRAPTEVVKSIIVNIEAGVEVEVTIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2W2</accession>
    <name>A0ABR3Z2W2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Sphingosine N-acyltransferase lag1</fullName>
            <ecNumber evidence="13">2.3.1.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">LAG1</name>
        <name evidence="13" type="ORF">Cpir12675_003429</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sphingosine N-acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.24" evidence="13"/>
    <dbReference type="EMBL" id="JAWDJO010000081">
        <property type="protein sequence ID" value="KAL1894970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050291">
        <property type="term" value="F:sphingosine N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016439">
        <property type="entry name" value="Lag1/Lac1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560:SF11">
        <property type="entry name" value="CERAMIDE SYNTHASE LAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560">
        <property type="entry name" value="LONGEVITY ASSURANCE FACTOR 1 LAG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="181"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="310"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="12">
        <location>
            <begin position="172"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="395"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="403"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1894970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="433" mass="50018" checksum="19175C3EF06ED994" modified="2025-10-08" version="1">MADEKEPLLTLSPPTTEDGSGPRRRRKSSLLGSEVRLGDTRAPALASSRIAMHANDSSSHPDKKSKKRRGRSLLHTAHSAMIKHTYLIPAVMLLAFVPLYAINPSPSNPIYHFIFLSYPFEQPTDGSPLQYGKGLWDIAFVVFYTIVLSFTREFIMQVILRPLARWFSLSRSKQARFMEQMYSAIYFGCLCPFGMYVMSRTPVWYYNTYGMYENFPHRTHEAIVKFYYLFQAAFWAQQAIVMILGLEKQRKDYKELCLHHVVSLTLIALSYRFHFTYVGLAVFTTHDISDFFLATSKTLNYIDSPIVGPYFFLFMCVWIYCRHFINIRILISLFFEFRTVGPFELDWENEQYKCLLAQGIATTLLSALQTLNLIWLSHIIRIAYRFIRYSTANDDRSEDESDESHTSAEKASLLDKKTTVAPPVEIKVTDSTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z312</accession>
    <name>A0ABR3Z312_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Double-strand break repair protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">MRE11</name>
        <name evidence="20" type="ORF">Cpir12675_003875</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Core component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The MRN complex is involved in the repair of DNA double-strand breaks (DSBs) via homologous recombination (HR), an error-free mechanism which primarily occurs during S and G2 phases. The complex (1) mediates the end resection of damaged DNA, which generates proper single-stranded DNA, a key initial steps in HR, and is (2) required for the recruitment of other repair factors and efficient activation of ATM and ATR upon DNA damage. Within the MRN complex, MRE11 possesses both single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. MRE11 first endonucleolytically cleaves the 5' strand at DNA DSB ends to prevent non-homologous end joining (NHEJ) and licence HR. It then generates a single-stranded DNA gap via 3' to 5' exonucleolytic degradation, which is required for single-strand invasion and recombination.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 16">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 16">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 16 17">Belongs to the MRE11/RAD32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000099">
        <property type="protein sequence ID" value="KAL1893899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00840">
        <property type="entry name" value="MPP_Mre11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.110">
        <property type="entry name" value="Mre11, capping domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003701">
        <property type="entry name" value="Mre11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038487">
        <property type="entry name" value="Mre11_capping_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007281">
        <property type="entry name" value="Mre11_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041796">
        <property type="entry name" value="Mre11_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00583">
        <property type="entry name" value="mre11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10139">
        <property type="entry name" value="DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10139:SF1">
        <property type="entry name" value="DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04152">
        <property type="entry name" value="Mre11_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000882">
        <property type="entry name" value="DSB_repair_MRE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01347">
        <property type="entry name" value="Mre11_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="9 16 17" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12 16 17" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 16 17" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="11 16 17" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="10 16 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13 16 17" id="KW-0464">Manganese</keyword>
    <keyword evidence="15 16 17" id="KW-0469">Meiosis</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 16 17" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14 16 17" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mre11 DNA-binding" evidence="19">
        <location>
            <begin position="290"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="535"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="535"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="579"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="608"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="635"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="676"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="697"/>
            <end position="720"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR000882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="SMART" id="SM01347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAL1893899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="732" mass="82078" checksum="08875F174801EF1D" modified="2025-10-08" version="1">MTEISDENIIRILVSTDNHVGYEERDPIRKDDSWKTFDEIMTLARTQDVDMVLLGGDLFHDNKPSRKSMFQVMRSLRKNCLGMKPCELEFLSDAQEVFEGAFSKVNYEDEDINIAIPVFSIHGNHDDPSGDGHLCSLDLLQVAGLVNYFGRVPEADNIEAKPILLQKGSTRLALYGLSNVRDERMFRTFRDHKVKWFRPAEAQADWFNLLTVHQNHHAHTATSYLPENVLPDWMNLVVWGHEHECLIEPRKNAETGFHVMQAGSSVATSLCPGEAVAKHVAIVNVRGREFTVDKLPLRSVRPFVMREIVLSQERRFKGLDRVDARKDMRLEITKRLMEVVDDMIRQAADEWLEMHPDETAESMPLPLIRLKVEYSPSEEGGNYDVENPQRFSNRFVGRVANTNDVVLFHRRKTTAKKSSNNSKANLPDSTEISVESGVKVDVLVQEFLQAQSLKILPQAPFGDAVNQFVSKDDKHAMEHFVSESLSGQVQQMLALDSDDDDLDAAMQSYRAQLDENFAAGAWSISGTRRRIREKPRGWDSDLEGHWEDRPEAQVAPNEAMDSDNEQPAPATLRGKRRTAAPARTTAAKTSARKTAAPRGRATKQVVIPEDDEVMDDLDDEPVPAPVPTRTGRGSRAAATVVPAARPRGAGSRAAAASSSSTTTTTRRTAATRQSTLSFSQGRTTSSRATKKSREVMEISDDDVEDDDNEDDDDEDDEDGFEPPPTATRSRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z369</accession>
    <name>A0ABR3Z369_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-(apurinic or apyrimidinic site) lyase</fullName>
            <ecNumber evidence="2">4.2.99.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">OGG1</name>
        <name evidence="12" type="ORF">Cpir12675_003581</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-1 OGG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000087">
        <property type="protein sequence ID" value="KAL1894642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="entry name" value="Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012904">
        <property type="entry name" value="OGG_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052054">
        <property type="entry name" value="Oxidative_DNA_repair_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10242">
        <property type="entry name" value="8-OXOGUANINE DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10242:SF2">
        <property type="entry name" value="N-GLYCOSYLASE_DNA LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07934">
        <property type="entry name" value="OGG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55945">
        <property type="entry name" value="TATA-box binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="11">
        <location>
            <begin position="134"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="328"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="402"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="418"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1894642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="430" mass="48956" checksum="96895F349CE23E8F" modified="2025-10-08" version="1">MPPRSTWAGEWRKIPLKLADLSIDTILRCGQSFRWRKFGNEWVCTLRGRVVRLRQDETALYYQAVWPAHKPAPKDNEDDTERLIRHYLSLDIDLQALYREWSAADSHFKKLAENFCGIRILSQDTWEALVSFICSSNNNISRISQMVQKLCIEYGPFVAKIGDEVFHDFPSPEEMAGEDVEATLRALGFGYRARYLADTAKNVANKPKDWLNDLRNPENPSYGSSITNPNATYKQAHKELLKLKGVGPKVSDCVCLMGLSWGESVPVDTHVWQIAVRDYSFGKGKPKAFALSMYEPVGDLFRDLWGSKAGWAHSVLFTADLRSFSDQKAGASSKTTVKKEEVKDEPDEDKMEVEYQPRKRKNSTEPPTIKSIKKSKRELAAKHMGAPTVKIEACDDTKIKAEDMDIDMMTPEPERPTRRSARLRGVKMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3N1</accession>
    <name>A0ABR3Z3N1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003797</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000096">
        <property type="protein sequence ID" value="KAL1894109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="589"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="3">
        <location>
            <begin position="39"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="425"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="510"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="548"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="619" mass="66592" checksum="D379B71327A1F002" modified="2025-10-08" version="1">MESNQTPEGVIVTLTARYANHHSCDPVRSLKLTKENNTALIGRASTSSRRRGNTKASPDNGLLHNPVVSREHAKFSYRNKSVYIRDCRSYHGTALNGTTLPPGLDVLVQDGDDVNFAILTGKLAETMKSYHFKVSISDLPLATPGPISEPDTLNKTGTFRAPVFLSDDESDAENTRENDGKKKQVIDDGQETAQERIEEDTKSNDEANTQAPREATAGFGCLWEAGFIPLHRISELDGAALPSFKPLWSIQSEVQSEAQSEAQSEAQSEAQSEAVYENHGTDTETPAAGPESGDFLSSDLEMNIDYSDEAESEEEDDDSFDSNGIFGYDDVDFQVHEKETAESEDEILAFVEETDGLAVEPGASLLAMEISQAPPVLETGLASQVSQATAFSTNLASFSANRSNSTGETSIIPISYLLSEIPETPVDEETTSPSPPPPSSRGDTQAAVNIGVCICETKNQFTTPEACDESRIMTPPSERIYEAKISNLSVISTPSSPSRKRKIDDISTDKALLSKNQGPDEGSISEVKIISTPPASAKKNTHERAYGSQSNSENQQNEEASHSTNVCYGDDNNKNSADQARPRKRIRTVVEAVGFAALGGAAAGLAILTAMIATAPELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z429</accession>
    <name>A0ABR3Z429_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Something about silencing protein 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SAS10</name>
        <name evidence="8" type="ORF">Cpir12675_003325</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000076">
        <property type="protein sequence ID" value="KAL1895308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007146">
        <property type="entry name" value="Sas10/Utp3/C1D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018972">
        <property type="entry name" value="Sas10_C_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13237:SF8">
        <property type="entry name" value="SOMETHING ABOUT SILENCING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13237">
        <property type="entry name" value="SOMETHING ABOUT SILENCING PROTEIN 10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09368">
        <property type="entry name" value="Sas10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04000">
        <property type="entry name" value="Sas10_Utp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sas10 C-terminal" evidence="7">
        <location>
            <begin position="540"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="315"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="384"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="428"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="132"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="117"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="391"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="434"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="616" mass="69903" checksum="D7EFB1404AF51E4B" modified="2025-10-08" version="1">MGRKRKAGRATGPTGPREVDAADARLGPINSYEDIADSQDEYFMNQDKVMLDDHSSKRQKMREEADAFLEESDDEVFDYGEDDDEDEDSAPKKSTKKDKKSGRDSNGEDEDEEGQEGDERWWGSSKKEYYNADAIETEADALEEEAEAKRIQHKKLSKMADEDFMFDENEWKTSEDKKTGEDIVTEVLGDAEIPDNISPEESLRLLSTRYPEFEYLATEFEELKPTLETVHKAAEGKDNKSLEMVRYIVLASYLATLASYFAILTSPARDSTDTHKTIDPAELREHDVMTALFKCRDMWTRVRDIKSTRSLEQNVTPMNSDYEGDSDYDSSNEVFYTPGKTPQKPRASKISKKKSSSEVVVSQEVEDDLADLYDMPLKISKKNLTASSSEEQADEGDSDFGEEEVLDEKAALEKAKRKKSLRFYTSQIVQKSSRRADAGRDAGGDMDIPYRERLRDRQARLNAEAERRGRKDSKFGAALDGADSDAEDSATRKAVNEDDEYYDLVVARSKKKRDEKSERFAAYAAAGKADRVVEVEDVDENGKRKITYTIEKNKGLAPKRKKENRNPRVKKRLKYEEKMKKLKSMKPTYSGPGESGYQGIKTGIKAGLIKSTKFQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z513</accession>
    <name>A0ABR3Z513_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleolar 27S pre-rRNA processing Urb2/Npa2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003329</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000076">
        <property type="protein sequence ID" value="KAL1895312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052609">
        <property type="entry name" value="Ribosome_Biogenesis_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018849">
        <property type="entry name" value="Urb2/Npa2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15682">
        <property type="entry name" value="UNHEALTHY RIBOSOME BIOGENESIS PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15682:SF2">
        <property type="entry name" value="UNHEALTHY RIBOSOME BIOGENESIS PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10441">
        <property type="entry name" value="Urb2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleolar 27S pre-rRNA processing Urb2/Npa2 C-terminal" evidence="1">
        <location>
            <begin position="1124"/>
            <end position="1352"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1353" mass="150710" checksum="6E08F30AFFE42634" modified="2025-10-08" version="1">MKPENNLAKLARSLEKTGPGAQGETLDELWRLLTTSIDSEHYAIEETVLRWLLKLMSGPATKTQAETVRRYPLTWTIIEHVFNRIPFFSLAKCLADRKFISILQLSLNNLSGAVSLPMALEGGKRKRSQNVFFDLKSLKSTECSLECAEALLAAIATLLARLDSQGLSSRDIMGAEHIKSLFASSANEALGLVTPILSLCSTAMSTSSLELRTKQKVWPSVMCSMWDLHRIGSTDAIEVASTTSLQVLQMISALDHRKYGTSKNQELPVEIQAVWKQKLENFYIRAVIFPARAAFLNSEDTEILGAIMGAIESKPLVCAPVLYTLSLDAPELNVGSLKSRENWHHQMFSSVQSILDPVCSYDKSLAMTLILDIARAREAAIQRESLHKVCKDYVLGSDSTQWSVLLRVLVCDRHVIFYPHGEELLSEELCRRASHVGSGDTCSGDEVQQVVRQMKLAYAEARDLSTFWKLWYNQLCFCESKNTIQSSPWLDETLRYDSTTSSNIESHMTPAQLSHLLQWLSEQSYAKAGPRYVLLDSIASQIRSPDFTDPTAVPIMNLALDSLKQVPSHGSLSTLRWCILAKIVHWLSPKERNKIWAEVEHELTQVAVKGSLENADAFEAFKFLDQLWLSMYPDGEYEPEVSAMALKIAKHLAKGGSKKAGVSNSNSESSFPSEYLDVATRVSSRLIPLLSAKSNTFPKFIRKHIINCESPDSTTFGYFSALISNENIVNNRKLVESLIDALINILSSNALASHKYSAISILASIPDDCFSRTSRESIMTSSMSFLTKPTIHESALWKISLGLMSKMMKRSTFYENISFDHLVLLSDSASACFSREQHARKLPEIYGLDVLFEELVSAIIKQMVSQFEEWGRPFLKTAEKFVAECPSDIEYLETRLLRIVLLKALIITVKKIGLKDPTAFDLDKAEKLLLSMVKKTILEYQSKSQAAVSSPYVILAAIDASEVVRDAASQIPKLKAKKLEPLATKGITQGTFLGWKTRIFLIHTLRDSVKSLPSQFQQGLAPEEGAPPDVLRFADYEALIRETLYAVTGPMDGNTLLAYFHSLIDALDMTKSTELQLKAIKICASIISSKQGADAGGAISISTAYNKLIIFATNAPNGHVFIKTCDILRLFLNSSSARLKQWNIEQTLAMVSDISGNPTSSMAVKDSPVVFDWLCKLMESVLRRFRVRLDGRFHLLIAALQSLLSGLLLAPYDAQLGKWTFQPANVRDGDFPYWGRHAASLTRLLTMVCEPMAASVAHHKKSPSNTLDTATDIAKRAAGRHMYLILVSYVKLQLQVDVPRPVRDALELGMNTIFNITPPEVRKILNDSLDMSGRAILGTQYKRYKQFGKWTGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z549</accession>
    <name>A0ABR3Z549_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Prenylated Rab acceptor protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PRA1</name>
        <name evidence="4" type="ORF">Cpir12675_003089</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000068">
        <property type="protein sequence ID" value="KAL1895756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029482">
        <property type="entry name" value="HRXXH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039124">
        <property type="entry name" value="PRA1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39399">
        <property type="entry name" value="PROTEIN ZPS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39399:SF1">
        <property type="entry name" value="PROTEIN ZPS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13933">
        <property type="entry name" value="HRXXH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047247707" evidence="2">
        <location>
            <begin position="18"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="Putative peptidase" evidence="3">
        <location>
            <begin position="15"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1895756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="274" mass="29476" checksum="0195FBCF8097D107" modified="2025-10-08" version="1">MHFSNLILAASTVLASSSPSLLTSRAESFSLESVTTINSPFPIHESCNSTQQRQIARGLQETIILAEVAKAHLLKHGGDSEIKKKYFGNGTTATPIGWYERIISANRGAMTFRCDDPDENCATQDGWAGHWRGNNASAETVICDASYHKRLYLESMCTRGYTVDGSALNLFWATDLLHRILHVPIISEDIVDHFSESYSDSIVLAESEPAKAAIDSNILQYFAVEVYAYDVAVPGEGCLGDGTTISKSSSTPQAPASSATSSAAGTVSKNPSFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5P3</accession>
    <name>A0ABR3Z5P3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Rhomboid-type serine protease</fullName>
            <ecNumber evidence="10">3.4.21.105</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Cpir12675_003216</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Serine protease involved in intramembrane proteolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains.</text>
            <dbReference type="EC" id="3.4.21.105"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Membrane</location>
            <topology evidence="2 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the peptidase S54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.105" evidence="10"/>
    <dbReference type="EMBL" id="JAWDJO010000072">
        <property type="protein sequence ID" value="KAL1895527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002610">
        <property type="entry name" value="Peptidase_S54_rhomboid-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22936:SF69">
        <property type="entry name" value="RHOMBOID-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22936">
        <property type="entry name" value="RHOMBOID-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="412"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="500"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="12">
        <location>
            <begin position="314"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="16"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="43"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="137"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="152"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1895527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="553" mass="60842" checksum="E4B8965B57375D46" modified="2025-10-08" version="1">MASNDYYYGSNAGYHDTNQQSQQSYTQPYVTASKPAPPYYAQGQGTPPVQPPSVSNTPAPPAYPPSSASRSNTGTPRPGHPHHGQSPFESVFDDHVYPDTDSTPAVHYTAASHNPNPNVAANTSYYNQDTAYHGGTQPHHQSSSSPSNDIPLENRNHSQNKVHDPEDFQDHVYDTPKKKRSRKRGKVSFGQLGMMGANTNRFPFLVYTLSIIQIGVFIGELIRNGVLTGSPIMTKPSFNPMIGPSTWVLINMGGRYTPCMHNIPKIQGHEGSISWPCPNTTTTTGYCSLSQLCGMGGVPEPLYDGNQNQSPEPNQWWRFITPVFMHAGIIHIGFNLMMQLTIGKEMECAIGSFRFFIVYMSGGIFGNVLGANYAGDGLLSTGASGALFSCIALVLLDLLYSWGDRRNPVKDLAFIMLDIGVSFVLGLLPGLDNFAHIGGFLMGLGLGIALLHSPNSLRRRLGLETPYTAVSSGVNDKQPSFFSNPTGFFKGRRPLWWGWWLLRAGSLIAMIVAFVVLLNNFYKYHNECSWCRYMSCLPVRDWCETGDLDITDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6M5</accession>
    <name>A0ABR3Z6M5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Very-long-chain enoyl-CoA reductase</fullName>
            <ecNumber evidence="11">1.3.1.93</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">TSC13</name>
        <name evidence="11" type="ORF">Cpir12675_003357</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the steroid 5-alpha reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.93" evidence="11"/>
    <dbReference type="EMBL" id="JAWDJO010000077">
        <property type="protein sequence ID" value="KAL1895174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102758">
        <property type="term" value="F:very-long-chain enoyl-CoA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001104">
        <property type="entry name" value="3-oxo-5_a-steroid_4-DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039357">
        <property type="entry name" value="SRD5A/TECR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10556">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10556:SF28">
        <property type="entry name" value="VERY-LONG-CHAIN ENOYL-COA REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02544">
        <property type="entry name" value="Steroid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="115"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="3-oxo-5-alpha-steroid 4-dehydrogenase C-terminal" evidence="10">
        <location>
            <begin position="157"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1895174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="307" mass="34322" checksum="9F7C0F1809477149" modified="2025-10-08" version="1">MASTITVKLTNRAKPLKKLPSEITIPSTATVEDVKALVSKQCGIHDRNRIGLYYPTSKKTIKDRKALISNETEIMTTGEMMVKDLGPQIAWKTVFLVEYFGPILFHVAIVALRPYIYAGAATTPLSSTQLLVFWMIVLHFVKRELETLFVHKFSASTMPAFNIFKNSFFYWAFSGLLSAWAIYSPTSLAATADQPLINYAGLAVYVFGELSNGLVHLHLSSLRSPGGTERKIPNGYGFSLVTCPNYLFETISWLGVIIVSRNWAVTLFIAIGVAQMSAWAKGKERAYRKEFGDKYKKKRFVMLPGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z717</accession>
    <name>A0ABR3Z717_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sphingolipid delta(4)-desaturase</fullName>
            <ecNumber evidence="8">1.14.19.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">DES1</name>
        <name evidence="12" type="ORF">Cpir12675_002840</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Delta(4)-fatty-acid desaturase which introduces a double bond at the 4-position in the long-chain base (LCB) of ceramides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>an N-acylsphinganine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = an N-acylsphing-4-enine + 2 Fe(III)-[cytochrome b5] + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:46544"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:31488"/>
            <dbReference type="ChEBI" id="CHEBI:52639"/>
            <dbReference type="EC" id="1.14.19.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.17" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000059">
        <property type="protein sequence ID" value="KAL1896436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03508">
        <property type="entry name" value="Delta4-sphingolipid-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011388">
        <property type="entry name" value="DES1/DES2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013866">
        <property type="entry name" value="Sphingolipid_d4-desaturase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12879">
        <property type="entry name" value="SPHINGOLIPID DELTA 4 DESATURASE/C-4 HYDROXYLASE PROTEIN DES2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12879:SF8">
        <property type="entry name" value="SPHINGOLIPID DELTA(4)-DESATURASE DES1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08557">
        <property type="entry name" value="Lipid_DES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017228">
        <property type="entry name" value="Sphnglp_dlt4_des"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01269">
        <property type="entry name" value="Lipid_DES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="Sphingolipid delta4-desaturase N-terminal" evidence="11">
        <location>
            <begin position="31"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR017228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1896436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="377" mass="43104" checksum="01EFD0F50315FB9B" modified="2025-10-08" version="1">MGAVHTSAGAASAKANPDTNVPDDQRDPIERKYKDFFWTYTEEPHRSRRLEIIKAHPEVTKLCGPEPLTKYTVALVVGIQLLAAYYLRDTPFFSLKFWAVGYVIGATANQNLFLAIHEISHNLAFRSPLANRILAIFANLPIGIPYSASFRPYHLTHHKSLGVDGLDTDLPTALEALFLDSIAGKAFFCTFQIFFYALRPMSVYRVPFTWVHYINILVQVVFDYAMYQTFGPNTLLYFLLSSFLAGSLHPVAGHFIAEHYVYESVSRQQRNPENKLMIPETFSYYGPLNFFTYNVGLHNEHHDFPAVPWTRLHKLNEIASEFYNDLPTHESWVYAIWRFIFDENVGMNCRVKRKEGGRLVGGGSGKNKWTDDEVESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z790</accession>
    <name>A0ABR3Z790_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">MICOS complex subunit MIC60</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Mitofilin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">MIC60</name>
        <name evidence="16" type="ORF">Cpir12675_002952</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a role in keeping cristae membranes connected to the inner boundary membrane. Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 13">Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Mitochondrion inner membrane</location>
            <topology evidence="1 13">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the MICOS complex subunit Mic60 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000063">
        <property type="protein sequence ID" value="KAL1896037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019133">
        <property type="entry name" value="MIC60"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15415:SF7">
        <property type="entry name" value="MICOS COMPLEX SUBUNIT MIC60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15415">
        <property type="entry name" value="MITOFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09731">
        <property type="entry name" value="Mitofilin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 13" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="63"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="209"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="390"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="63"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="15">
        <location>
            <begin position="115"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="228"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="243"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1896037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="663" mass="71871" checksum="A18A55A97982841B" modified="2025-10-08" version="1">MLRSSISSVKVLNSCTGAGAGAAARQLGPTARRYFASKPSQPVTPAASSVAAKVAAAKAAQAAVTSTTPVTPTAKSATTTTVTTTPHTATIKPAPASASTPPPASTASKPAEKSTPPPPPQPPKKPGFLRRLRNFVFRLALLGVIGFAGGVWYSRMNDDFHDLFTEYVPFAEQAVLYFEERDFRKRFTDSLSHSKQLDATVAVPAQSGASWRVADSKDARRTSAGPIETKKADPKVEVKKAAPKPVNVEPKATPKPSAEVVKKAAPAPKKEPEFVAPQVNEPSRIPPVPKIDLLKMKNAEDPIVQDLVHIVNDLIVVINADNAQGRYGSTIVKAKDGVNNVLNKIEGVKNDAKKNAAAEVSSKVVEFEKAADEMVQRVEQVMVNQEIIWRQEFEQDMERIQKAYEEKVQLLQGREQKLMQERLNAQLMEQAVILKRQFTKEVKAQVEAEREGRLAKLRDLSAAVSGLEKLADGWNAVVDSNLQTQQLHVAVEAVRASLENTHNSKPFVSELVALKEIAAEDPVVDAAVASINPSAYQRGIAAPAELVDRFRRVASEVRKASLLPENAGVASHASSVLLSKVMFKKSGLADGDDVESILARAQTYLEEGDLDNAAREVNGLSGWAKMLSRDWLGEVRKVLEVQQALDVISTEARLQSLRLEQQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z830</accession>
    <name>A0ABR3Z830_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translation initiation factor eIF2B subunit beta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eIF2B GDP-GTP exchange factor subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">GCD7</name>
        <name evidence="12" type="ORF">Cpir12675_002833</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000059">
        <property type="protein sequence ID" value="KAL1896429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="entry name" value="Translation initiation factor eif-2b, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051855">
        <property type="entry name" value="eIF2B_beta_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45859">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45859:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="213"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="191"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1896429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="459" mass="49907" checksum="0B390D553CD7BE7B" modified="2025-10-08" version="1">MASNSSGFMPDLSKFIRFVNSRPLEASIEYLVSLFKRRQITGPKDCAVATAHLLFQVVKYSKWSDEEQLMAQVCRVGKRLADALPKELAIVNIVRRVLSVIHDEANEDRDNDAFSDTASEVYENTQHNAAIANANLAAFSSKHICSASIAETLGSIAPPRLTRQPTLSTISSFSTPKSLFNILSASPSGTAFASPTKTSGTSTPHGPSKAARADSLRSEIMNAIEEMKDEIDQVAEQIASFAEAQIRPGDYVLVHEPSSVVTRFIVKAASKRRFTVLIACKAGPRGYEARAVSVGCKDKKHVAYESFRRELTKAGITVINVMASGMSTYMSLVTRVVLGARSILANGNVIMDAGAGAVAHSAKYHGRPVVVLGGIYQLSPDSPFDEGSLVEWNDPSIAVAFEDGSLVCDDIIVRQPLTEVLPAELVDMYISNLGTHCQNHLSSLIMEHYKAEDVEFHQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z848</accession>
    <name>A0ABR3Z848_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">sn-1-specific diacylglycerol lipase</fullName>
            <ecNumber evidence="14">3.1.1.116</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Cpir12675_002854</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 1,2-diacyl-sn-glycerol + H2O = a 2-acylglycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33275"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17389"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="EC" id="3.1.1.116"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:33276"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.116" evidence="14"/>
    <dbReference type="EMBL" id="JAWDJO010000060">
        <property type="protein sequence ID" value="KAL1896261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052214">
        <property type="entry name" value="DAG_Lipase-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45792">
        <property type="entry name" value="DIACYLGLYCEROL LIPASE HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45792:SF7">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G02710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="16">
        <location>
            <begin position="929"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="420"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="646"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="420"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="464"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="508"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="532"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="550"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="647"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="15">
        <location>
            <begin position="732"/>
            <end position="744"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00026104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1896261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1252" mass="135698" checksum="0C18902AE846855F" modified="2025-10-08" version="1">MSSAMQKNQANAASLLPVPHGPTLLPGPLAFAVTAMTQTTGTLIRASSKVTTWSMDVARTTTVSSLGVGMSILETAMYLAGRDVQQIAGLPPAVGHVEPVVEASLDALYRGMTCLVFLVATSFRLSSTMVETTSHSTLVFLTVLNQFFGSTDSSRAMASIIALIRREFRNPATGIQGETVGVKDLLISMAAFAYLQNACLRLTDEGDHINEIDEMLWDVVVLDDGVRIDIHDIHDISLYGSHKGKYENRTGQARNIGPSPGASSSFLSAIDHIPMATQSHVEDAEAALHKQITAQLPANAKVLVSTNTVTTKTITVDIPTSTTPNFQLTPPPGAVIVRQQSMSGPGSHMHRIVYRVQRCEASSAAMEKVMDDAPDNAAPTDFGSMENEFEPSFLPQAPSSPMHTSPPLVRPMMEVLSRPSTATGSVSTLVPSPPQTTADSNVISPDIFSPSTTPTKNLPLGFPSVASSPSTSSTMGSTTNLPGFLGAESPFSGSHPAAPEVLEPNPKSPSKMSANPPRQKSFLRSGRCSVDSLRDCSKQDPRRRDPETFTMPTTSSSNKQKSPSAWKFPEKRNSFKNSLKIGSASSISSLWNRDSSGHYTKLGHKKASKSSALQMDRYLANLPSGDDNNKNPPTMRGGEAIERDVVASTSKCPASTTSPQGSPCSPTDEARNRKYPSVPGGPPPPMPRDNNNNGKGCGEANATALTIRPRQDVARISSRSRNYSTMRSLSPSPSPSPSLSPSPMTPRARQKSRSLGSRHGLSMGGNISSIHRHPQVFNSDIYSLETTNDSESSLVFSSLLSYHQRSAYNTEALKSLRTTGMIETTFPRFHILRNITRYILFSSASYGSHFLRYLGLSPEERLRFKPAAYKTHRDVRAFAQHTNIPPESVILASFVDAEGGSNSQGNVGTGSSVPLVHYIALDHESKAVVLACRGTLGFEDVLTDLTCEYDEMQWHSQKFQVHKGIHASARRLLYGEDGKVLATLKATLDEFPDYGLVLTGHSLGGAVTALLGVMLAEPNPDPRTLGFVTASKTKTRDEHAHLRPPSGRPIHVYAYGAPSTMCRRMQKATRGLITSVVHGNDVVPYLSLGVLHDFQALSAAFKSEGSSARAALNKYVTEQLQNEFLRRWYGSSAEGLSGTQGTLVTNGDRPQWAISLLQTLRGSMKSEKLLPPGEVFQVECTSVLRRNYVGQRSTIQGSLGSPAKRIVLRYVRDVSARFKEIRFRPSMLMDHSPSRYEESLNRLRVGVEQVWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z882</accession>
    <name>A0ABR3Z882_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">E3 SUMO-protein ligase pli1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pli1_2</name>
        <name evidence="3" type="ORF">Cpir12675_003120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000069">
        <property type="protein sequence ID" value="KAL1895729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14944">
        <property type="entry name" value="TRAPPC6A_Trs33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037992">
        <property type="entry name" value="TRAPPC6/Trs33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12817:SF0">
        <property type="entry name" value="GEO08327P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12817">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="43"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="49"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="64"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="240" mass="25663" checksum="9D4E6E2ED3960C3F" modified="2025-10-08" version="1">MSFQSIVQPTSMNPDSAYLASSCLDFLLIELVPLAFRVTNDLEPEPSPANDSTASATGSSPQVGGSATAGEASASSVPTKSGLGSGLGAGIVGAGDTVKKMDEDEEKDAVFYRLESLGYRVGQGLVERFSKDRPRFNDTLDVIKFLCKDLWMLAFRKQIDNLKTNHRGVYVLTDNNFRPLSRMSAEAGGQAVLQAQPFLWFPCGIVRGALAAMGIDATVSADTSELPTAIFQVKTLTTKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8D8</accession>
    <name>A0ABR3Z8D8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Syntaxin binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sec1</name>
        <name evidence="3" type="ORF">Cpir12675_002579</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000052">
        <property type="protein sequence ID" value="KAL1896931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.830.10">
        <property type="entry name" value="Syntaxin Binding Protein 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043154">
        <property type="entry name" value="Sec-1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043127">
        <property type="entry name" value="Sec-1-like_dom3a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="604"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="637"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="712"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="733"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="748"/>
            <end position="758"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="758" mass="85471" checksum="94C73D47786A4A5F" modified="2025-10-08" version="1">MSSSVIEEHRQVMLSAIERVTRGDWKVLICDKTSRQTLSVIPDDDILNKNIMNIEVLEDRREPNPDMDAIYFLSNTSFTVDCLLADLEHRKYRSAYLLWTGRLLPKDEERIHKSPAARMIRGFEVLMIDFQPRESHLVVFKDPWSFPLLFHNGCNEFVAPHMRVLAQKIASVCITMGEAPKVRYYMPPNPRHEASVLCTHLARFVQEEFDNYSRRFPDFPPKTSRPPGTLLILDRSMDLIAPIVHEFTYQAMAHDLLPIEEGDKVTYSVLINQGIPEEESKVMELQEKDKVWTENRHRHMKDTIGRLMSELQKFMSANHNFVNPDESKTSLNTIKDMMAGLPQFQETKEAYSLHINIAEQCMALFQQRKLPDVAAVEQTLATGLDEDLRKPKGVLEQVVRLLDDDAVPHADRLRLVIMYILFRDGIITEDINRLLAHSQLPLQDRDLIFNLNGLGALATRDLKDPRPLPEPLFPPDTSQPVDEEYTLSRFKPVLKYVLEELAKGTLRQDVFPYIVPPQNPNEDLIAAQSGSLRAARGNWAASGRRQPENRQRNFVFIAGGATYSESRCCYEIANEQNKDVYLISSHMQTPSLFVRQVADLNMPPKTLDIPMMRPRQRPPAHLFESHRPQPPPPKPNGQGGGHAGYGPTGGAPPGGGSSGSAPPSGGQRMAMPHGQGGAPLRPPVAPPTAAMSQMKLGAPAGGVPQRPMHQPHPSSASAMSNVSHSHSHSQPHSADDKKKDKDKDKKDKEKKKRHFFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8R4</accession>
    <name>A0ABR3Z8R4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ATPase inhibitor, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">INH1</name>
        <name evidence="7" type="ORF">Cpir12675_002910</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Inhibits the enzyme activity of ATPase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the ATPase inhibitor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000062">
        <property type="protein sequence ID" value="KAL1896203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.500">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007648">
        <property type="entry name" value="ATPase_inhibitor_mt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04568">
        <property type="entry name" value="IATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64602">
        <property type="entry name" value="F1 ATPase inhibitor, IF1, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="59"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="96" mass="10674" checksum="BE3F10436D311CF0" modified="2025-10-08" version="1">MIRPSVSKAALRAVVSGPRAFSVSTRVMSAGDAGSPPKTGGQGDAFQRREKANEDYIVRQRENEKLLALKKKLEEQKAHLQELSDHIDELTKEDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z979</accession>
    <name>A0ABR3Z979_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NB-ARC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002732</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000056">
        <property type="protein sequence ID" value="KAL1896636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF6">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1896636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="663" mass="74573" checksum="B278B40344FE949F" modified="2025-10-08" version="1">MPAHLLHDNSEFSLFPFSAVLATTKTNIGAPPALFRTDETTASWSKCTIWEVARATSAIVNLFEPIKLGRDVDEFMNSSLGHSNSCRILITEAKKLLSDGQKMLILSIGTGLGDFIEIGDTKSSFQDALNKMATNSDRVVRELTGEYSNDKGRYYRFNTNDGLREMALLDRVEWSEVSAHAKNYVGEKKDDIKKFTNVLKNGFPQASKQLRSADGHLPVYYIPIHENSQFVGRREILFKLNENLFTKPGFQHVALVGLDVFRNSCKELAERLKLKLADTDDPRAAVKEYLESSSSGKWLLIVDNVDDASLFETATKEQRISIFLPRSAEGRIMLTTRSKKAAQLAVKQISHILKLEEMSSEDLTTLLKHKVEGLGNQWLMQHKSQADELLIELCYLPLAIARAAYYMAFNDISIADYLELLREPKEGKVELLKHSHTDDAHLDHCQGVLATTWIITFNQIQEASQDAVKLLRFIAHVDPKAIPESMLPSFEVKKQMVDTVGILLAYGFIRRQETKGLIGMHSLVHLTTQLWCEDLQDRKEQKLAVLEHMTSIFPDDEWETRFLRRQYLPHALHVAEIEKVSEKRLAPLAFKVGLCLQSDGDTKGSVKLLEGVTQMRNEALGTDHSGCLTSQHNLADAYRADGQITKAVSLLERAVEVGDNSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAB0</accession>
    <name>A0ABR3ZAB0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Fluoride export protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_002437</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>fluoride(in) = fluoride(out)</text>
            <dbReference type="Rhea" id="RHEA:76159"/>
            <dbReference type="ChEBI" id="CHEBI:17051"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:76160"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000047">
        <property type="protein sequence ID" value="KAL1897254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003691">
        <property type="entry name" value="FluC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28259">
        <property type="entry name" value="FLUORIDE EXPORT PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28259:SF1">
        <property type="entry name" value="FLUORIDE EXPORT PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02537">
        <property type="entry name" value="CRCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="185"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="270"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="306"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="401"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="88"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="88"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00035585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1897254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="428" mass="45634" checksum="8E55AB717A067BAE" modified="2025-10-08" version="1">MGKWLSQIVIHGHLVLWSILGVLARLGMIGLTEYPNAPVTFGVLWANVAGSFVMGFLLEERVLFVETVKSKIHGTGVLPRLAVSAVQKERRGEEAAHREITEPESEVKPKSVPRSDSHISHEDRASPGEMHEEGDDAGDMDAEDANLELMQSLSESEGRGGSLPRDSAQTVQLADFVRAKKTIPLYIGLATGFCGSFTSFSTFVLDAFLAAVNQLPSDSSTRAGGDSFMAFAAVALLNLGMSLAGFHCGTHMARALGHLRVGLGGIPDSLLPALDKVAAVLGYGCWIGAVFMTAFPPHDHWRGKPLFSLVIGPLGTMLRFHLSAFNAGRKYPLGTLAANLLGTALLGAFFDVMHVPTRSVIGCQILEGFSDGFCGCLTTVSTWVAELAALSTKRAYKYGMASFAGGFIILIPIMGGLYWAEGFGTPVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAC2</accession>
    <name>A0ABR3ZAC2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutamate racemase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002373</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HyuE racemase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000046">
        <property type="protein sequence ID" value="KAL1897269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015942">
        <property type="entry name" value="Asp/Glu/hydantoin_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052186">
        <property type="entry name" value="Hydantoin_racemase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053714">
        <property type="entry name" value="Iso_Racemase_Enz_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28047">
        <property type="entry name" value="PROTEIN DCG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28047:SF5">
        <property type="entry name" value="PROTEIN DCG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01177">
        <property type="entry name" value="Asp_Glu_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="249" mass="26753" checksum="49E73CD371627474" modified="2025-10-08" version="1">MSKGAKKVLDAHAASLTNTAAEVTIYTAPETSPASIDDDEGIEASCKAVQVDISHRVSYLQSFDAVLIACFSVNPLVGEISELANKDRTQKAPVTGIFEASVLDAHRRAIAAHSTSTSDEKHEIPRWGIVTTGKFWEKHLAEGVADYLQIEPDQNPYFAGVFSTGLNAGDFHNIEPDTVEQRLCQAVERLLDVGNVQSIVMGCAGMAGLEDIIRSAIARKYGDKSKDVVIIDGLRSGLTKLAAIVEAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAQ2</accession>
    <name>A0ABR3ZAQ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Fumarylacetoacetase</fullName>
            <ecNumber evidence="3 10">3.7.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Fumarylacetoacetate hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Cpir12675_002242</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>4-fumarylacetoacetate + H2O = acetoacetate + fumarate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10244"/>
            <dbReference type="ChEBI" id="CHEBI:13705"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18034"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="EC" id="3.7.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the FAH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.7.1.2" evidence="3 10"/>
    <dbReference type="EMBL" id="JAWDJO010000041">
        <property type="protein sequence ID" value="KAL1897743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.230">
        <property type="entry name" value="Fumarylacetoacetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005959">
        <property type="entry name" value="Fumarylacetoacetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015377">
        <property type="entry name" value="Fumarylacetoacetase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036462">
        <property type="entry name" value="Fumarylacetoacetase_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01266">
        <property type="entry name" value="fum_ac_acetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43069">
        <property type="entry name" value="FUMARYLACETOACETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43069:SF2">
        <property type="entry name" value="FUMARYLACETOACETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09298">
        <property type="entry name" value="FAA_hydrolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63433">
        <property type="entry name" value="Fumarylacetoacetate hydrolase, FAH, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 10" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="domain" description="Fumarylacetoacetase N-terminal" evidence="12">
        <location>
            <begin position="18"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="11">
        <location>
            <begin position="156"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF09298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1897743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="452" mass="48917" checksum="593B0B336E48429E" modified="2025-10-08" version="1">MPLASWIEIDAQSGFSLENLPFGIFNTKSDPRPRVGVAVGQNVLDMAQLTTHPAFAQTFPMLQGLNDVFRASSLNAFAALGRRTHCAVRERLQDVLRTDTSYTGFLRDNAEFQARVLLPRDQAVLQLPVEIGDYTDFFAGYHHALHTGTMFRGKADALQRNYLHLPVAYHGRASSVVVSGTPVQRPMGQILETAPGAVGSAMPAAGMGVVATMPVTGLSRRLDFELELGCIIATGNKLGESISVDKAEEHIFGYVLLNDWSARDIQAWEYVPLGPFNGKNFATSISGWVVLADALEPFRTQPLEIQGKGSQEYLQEANPRSVFDISLEVLLEVKNKPESGGNEASSSETPITRVSSKNLMWSFPQMIAHHTLGGCPLRTGDLLGSGTISGETEDSRGSLLELSEAGKKDVVMSDGSVRRFLEQGDTVTMRGVCVGADGVRVGFGDCYGHIAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB10</accession>
    <name>A0ABR3ZB10_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_002225</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000040">
        <property type="protein sequence ID" value="KAL1897798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031359">
        <property type="entry name" value="NACHT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25173">
        <property type="entry name" value="Beta-prop_WDR3_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17100">
        <property type="entry name" value="NACHT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="NACHT" evidence="5">
        <location>
            <begin position="410"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="917"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="959"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1001"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1043"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1085"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1127"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1169"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1211"/>
            <end position="1252"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1253"/>
            <end position="1294"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1295"/>
            <end position="1336"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1337"/>
            <end position="1378"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1379"/>
            <end position="1419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="38"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1897798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1510" mass="167787" checksum="18AB047C503ADEBF" modified="2025-10-08" version="1">MPIKPLGETDDINHELAEPWTKVYRIFKAGTRYSGSATSLITSSSGPVQSLPTTGTPSPPPAPEPKPAPLASIQETVWRRAYDDLRKEEPELVKAFESIVYNTLRLNEKNAGSSETTESKAVAARKVSAREMQQIVRDRINRTKNEASLQREISDGLRAAHAVRGLMDSALRTAPEAAIIWATVCLGIEILSNPVTEALENRKGMQYVLCRMEWYWNLADLLLDENKGETATTSMRDELEKDIVRLFEKLLLYQMEIICLYHRSRSVTFVRGMFQIDDWGGQLSGIKEAEEAVRYDIEQYNNQESQVQLQKLDNTADALQQSFQSISTAVKTQTEYLHDIHAAAQDQAEQQAKRHEEDKDKQCLSELFVTDPRIDKKNIEEKKGGLLKASYQWILEHPDFRRFQPENDSPILWIKGDPGKGKTMLLCGIIDELELDPSASLSYFFCQATGGDRLSSATSVLRGLIYYLARRNPQLVKHVRIKYDYMGKMLFDNEGAWHDLCEIMTAILNDPSLENVILIVDALDECSVDRKRLLDFIARPSPAKWIVSSRNWTDIEEVLDHTRQNVQIDLEMNRESVSMAVESYLQLKVDQLAQERKYNEGMKANILRYLRANADGTFLWVALVCQELSNVNIRKRHTLDIVNSLPSGLAPLYSRMLEHISQSKDAQICGKILSIAAVTYRPITLEELRVFVEELEDLELEEVKEIIDSCGSFLTVHQDLVSFVHQSAKEYLLSEAPGKILPYSIAHQHQMVFLRSLDLLCGELSRDIYGLQAPGYLIDQVSVPKPDPLASIRYSCLFWVDHLRDSTAGVMASGNDRILDFFKEYYLQWLEALSLLSSVSVGKKKASQELQEIIKDARRFLLSHRDIIEVAPLQVYVSALIFSPTSSLIRRFSQEELSWIELKPRIEADWDACLQTLEGHGRGVTSAVVSSDGLRLASGSRDNTVKVWDATSGACLQTLKGHDDWVRSVAFSEDGRWLASGSDDKTVKIWDAARGTLLQTLKGHGEPVISATFSKDGRQIVSGSYDKTVKIWDVSSAVCLQTFMGHDGRVISVAFSSNGQQVASGSRDKRVKVWDATSGACLQTLKGHGGWVRSVAFSKDGQRLASGSDDKTIKVWDTASGTCLQTLEGHDDLVSSVAFSNDEQQLASSSNDKTIKIWDATSSTCLQTLEGHDSGVTSVVFSENGQRLVSGSDDGTVKIWDVASDVYMRTSKAHNDRVASMAFSDDKQRLASGSRDNTIKIWDATSGACLQTLEGHNSWVRSVTFSRDGQRLASGSRDRTVKIWDATSSACLQTLNGHSEMVASVAFSTDGQRLASGSHDKTVRIWDATSGTCQQKLEGHDGWVSSVMFSNDGKRLASGSHDTTIKIWDAISGACLQTFGGHDDWVRSVAFSEDWQRLASGSYDKVKIWDASSGACLQTLLIGGAIRCCSFDPLNDSLLSTNIGVLHLDMPVSAAIPPAGQVSLPTANIHGYGLLTDPDLVRLNVRASVRRKGPSSKAHIVSLDMEAMDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBY3</accession>
    <name>A0ABR3ZBY3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CST complex subunit Stn1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_002192</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
            <location evidence="1">Telomere</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000040">
        <property type="protein sequence ID" value="KAL1897767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018856">
        <property type="entry name" value="Stn1_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10451">
        <property type="entry name" value="Stn1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0779">Telomere</keyword>
    <feature type="domain" description="CST complex subunit Stn1 N-terminal" evidence="4">
        <location>
            <begin position="67"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1897767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="291" mass="33780" checksum="DD48FA3681FB9A8E" modified="2025-10-08" version="1">MTSEPLSLYPRYCFDLSPTFAAWCFLKIGDTRRLSRLPEYEGKLCCASKGLYVPLSQPFTNLFTISGQNFFFYKNLPIRWVRFVGLIVSILEFPNRHIYTLDDGSGDILECILWDAELKDGSNNTHGNNETQKSQPSINWPDFGPGQLVDAKGELTWYKSTWQLRLTRIVIVPDTAAELELWDKRLAFRRDVLTVPWVLSDKEVRRARRKAEMEELNPQVDDRKDGYIKQADGLDWDEIERLLPSDATALKTAWRRVEGHKKADLVWDINVALAKRRKAERKRLKYSGLSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC12</accession>
    <name>A0ABR3ZC12_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Branched-chain-amino-acid aminotransferase</fullName>
            <ecNumber evidence="10">2.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">BAT2</name>
        <name evidence="11" type="ORF">Cpir12675_002223</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-isoleucine + 2-oxoglutarate = (S)-3-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:18321"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-valine + 2-oxoglutarate = 3-methyl-2-oxobutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24813"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="10"/>
    <dbReference type="EMBL" id="JAWDJO010000040">
        <property type="protein sequence ID" value="KAL1897797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004084">
        <property type="term" value="F:branched-chain-amino-acid transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01557">
        <property type="entry name" value="BCAT_beta_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018300">
        <property type="entry name" value="Aminotrans_IV_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005786">
        <property type="entry name" value="B_amino_transII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033939">
        <property type="entry name" value="BCAT_family"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01123">
        <property type="entry name" value="ilvE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009897">
        <property type="entry name" value="PRK13357.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825:SF44">
        <property type="entry name" value="BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825">
        <property type="entry name" value="SUBGROUP IIII AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006468">
        <property type="entry name" value="BCAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00770">
        <property type="entry name" value="AA_TRANSFER_CLASS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 10 11" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7 10" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 11" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1897797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="419" mass="46426" checksum="72AB05CD7C701039" modified="2025-10-08" version="1">MRRTVSSLASLSRAVSTTAAPSNRLPGSRLAPALAKQWQWKRMYSSSHAGAPLDASKLTIEKTTKPSALKDPKDLVFGRTFTDHMLVVEWTKEAGWGTPKIQPYQNLSLDPATCVFHYAFECFEGMKAYKDAEGTVRLFRPDKNMERFNKSTARIALPTFDPQTGIELISKFVEVESRFIPEQKGYSLYLRPTMIGTQKTLGVGAPGSAMMFVIASPVGPYYPTGFKAVSLEATDYAVRAWPGGVGDKKLGANYAPCIVPQIQAASRGFQQNLWLFGDEEYVTEVGTMNFFAAIKNKQTGVNELLTAPLDGTILEGVTRDSVLTLARERLVPEGWKVVERKFSIKELYEADKEGRLLEAFGSGTAAIVSPVRNISWKSQMILCGLKAEEESGPIARRMKDWIEGIQTGEENHKWSYVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCA7</accession>
    <name>A0ABR3ZCA7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Prefoldin subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002023</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000035">
        <property type="protein sequence ID" value="KAL1898315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23157">
        <property type="entry name" value="Prefoldin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00308">
        <property type="entry name" value="PfdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011599">
        <property type="entry name" value="PFD_alpha_archaea"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004127">
        <property type="entry name" value="Prefoldin_subunit_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00293">
        <property type="entry name" value="prefoldin subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12674">
        <property type="entry name" value="PREFOLDIN SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12674:SF2">
        <property type="entry name" value="PREFOLDIN SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02996">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="114"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="159" mass="17571" checksum="3A1153C99194CBE2" modified="2025-10-08" version="1">MSSSQSQGQSVSIDSLDVQQLSMLKKQITEDLEHLSASFTSLNAAHSKFKESLRCVQARASAPEEPEAALVPLTTSLYVRGMLEDKKRVLIDIGTGFIVEKNLEDAVKYYEIKIKDLSKSLKELETIIAQKTMNVQAVEEALRQKMMASQAAQAKPQVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCB7</accession>
    <name>A0ABR3ZCB7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002029</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000035">
        <property type="protein sequence ID" value="KAL1898321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="546"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="724"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="828"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="355"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="448"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="494"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="546"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="561"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="614"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="648"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="658"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="669"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="724"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="738"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="793"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="840"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="874"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="902"/>
            <end position="914"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1000" mass="107886" checksum="286FFC504E601C2C" modified="2025-10-08" version="1">MPSFPISFAPRAEANAKDGRKRYVPSKLHATAISDFGNFGVMNFRSEAATSSTQNAKPTRKLTNELQARRINEGTVIAAKLSQKDALKKKSAIRHTPNTVLAGLSTSSSTTTSPTVSTSTSSDDNTFNLNHTLTQLPRQHTVPLPVLSASRTSTTSSRDDNSSTEHMQEPIAQMQQSHTGLPIQTSMQPQSNLMQSILPPAQNQGTASASDATSIKEEQARLLNLLQNLQPTKVVERLCNSIVHFGGGQPSNSSENVIFPASANSNGSGANLISWLSEIFQSNSFTAADSVQMAILPVKRPRGRPKGSKGTKARKDKGIKKGPMAKKKKEAQNGTTHTDPKPASEPATDDEHVNSSVAGGQSSSSQSRQQGQQSGPLGQCHTSFTSMHGQGVNEAGENSWVDIDDSVMDGRRSVMNSMPAQQQAISSTAADETIPPSTPVTADSSAAMKRRGRPKGSKNKPKDSTADGGDQPGTAGNESPGIDSPAKKSRPKASKASAGQPEQAAVAAEEPPMIDNHNMQFPEKPILSTPTLSQQFGGHVNQIQSAQIQQPQMPQNQLSQSHMAQGQGQMSPNSMQQNQITQGQMPQGTPVISSATTIQEAATRKRKSMPVPNDQYNQATSQIAEQEQRIWTAPHASQTKRPRVAGESGTNTWPATDSSQSQASMGSSFAPSLQQNPMIAQSSPSQGMTSMQNPMSQNHHTHAGTETQRAALGYPQSQHLQNRSLHANHSQQTNSMVPPQQQQQQQQAQQSHTQQGPHQHATSQHAQQQAQQQQYPQGQQQQQQQQHNSQQHMMSSRFPQLRGSATANPSSKVNHPALHSITAVTAPSPYMSASGSHSFQQQQQQQANAQQLPPPQANANFQYQPGSRPDASLFAQSAGASGTTQQPPEMYRFNNPMFDLIPGANPAAPGAARGMQFPHSQSATPAQVRAQAQAAQQQQQQQQQQQQQQQQQQQQQQSNAYGMNMRRRQMPHQAAGAPMGYSFESHAPVDNGMFQLNQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD16</accession>
    <name>A0ABR3ZD16_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Meiotically up-regulated protein 86 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mug86</name>
        <name evidence="7" type="ORF">Cpir12675_002136</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000038">
        <property type="protein sequence ID" value="KAL1898047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051633">
        <property type="entry name" value="AceTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047622">
        <property type="entry name" value="GPR1_FUN34_YAAH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF038013">
        <property type="entry name" value="AceTr_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123:SF1">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01114">
        <property type="entry name" value="GPR1_FUN34_YAAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="246" mass="26824" checksum="1C2A1C01DDDF4E62" modified="2025-10-08" version="1">MSHDSIEKGHGPNYHEDRVVVQASQLRPYEHRKFANPAPLGLSAFALTTFVLSCINMRARGVHTNTIIMTLAYAYGGFVQMLAGMWEFAVGNTFGATAFTSYGGFWIAFGILTTPAFKLTNTVDGPYAEDAKDLNSAIGFFLTGWWIFTTLLLLCTLKSTVMFFMLFFTLDIAFLCLAVENYALSEGAVEIGHNLATAGGLFGMLAAFLAWYNALAGLQDSSNSFFKLPVFPMPWSDAAKGISSGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD86</accession>
    <name>A0ABR3ZD86_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Adenylyl-sulfate kinase</fullName>
            <ecNumber evidence="4 11">2.7.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">MET14</name>
        <name evidence="13" type="ORF">Cpir12675_002027</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the synthesis of activated sulfate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenylyl sulfate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24152"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the APS kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.25" evidence="4 11"/>
    <dbReference type="EMBL" id="JAWDJO010000035">
        <property type="protein sequence ID" value="KAL1898319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004020">
        <property type="term" value="F:adenylylsulfate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02027">
        <property type="entry name" value="APSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00065">
        <property type="entry name" value="Adenylyl_sulf_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002891">
        <property type="entry name" value="APS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059117">
        <property type="entry name" value="APS_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00455">
        <property type="entry name" value="apsK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003013">
        <property type="entry name" value="PRK03846.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11055">
        <property type="entry name" value="BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11055:SF1">
        <property type="entry name" value="PAPS SYNTHETASE, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01583">
        <property type="entry name" value="APS_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="8 11 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APS kinase" evidence="12">
        <location>
            <begin position="23"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1898319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="206" mass="22828" checksum="5CCC1E8722B04D43" modified="2025-10-08" version="1">MATNITWHPSLKRDEREALRKQKGFTLWFTGLSASGKSTVAIALEQHLLHLGLAAYRLDGDNVRFGLNKDLGFSEADRNENIRRIGEVAKLFADSATIAITSFISPYRADRDSARALHAAAQSDDAAIPFIEVFVQVPLEVAEQRDPKGLYKKARAGEIKEFTGISAPYEEPLNPEITIRTDLKSVEECVVDIVAALHERDLIPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDI5</accession>
    <name>A0ABR3ZDI5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">UBP15</name>
        <name evidence="11" type="ORF">Cpir12675_001932</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000033">
        <property type="protein sequence ID" value="KAL1898387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03775">
        <property type="entry name" value="MATH_Ubp21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02659">
        <property type="entry name" value="peptidase_C19C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002083">
        <property type="entry name" value="MATH/TRAF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024729">
        <property type="entry name" value="USP7_ICP0-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029346">
        <property type="entry name" value="USP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF644">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22486">
        <property type="entry name" value="MATH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14533">
        <property type="entry name" value="USP7_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12436">
        <property type="entry name" value="USP7_ICP0_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00061">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50144">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="MATH" evidence="9">
        <location>
            <begin position="61"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="10">
        <location>
            <begin position="216"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="806"/>
            <end position="827"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1898387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1145" mass="132414" checksum="396D180FFE8D4B09" modified="2025-10-08" version="1">MAIDEDDEYLHQPEAVVNIPASEPVPEREDQSQNVLMADDYEAMKELVLPPLLEEPRILEDAINTWSVENWRSMSKKEHGPIFQAGGFPWRILLFPHGNNVDHCSIYLEHAFQSQEIPPNWSCCVQFALVLWNPKDPSVYHEHNAHHRFTKDESDWGFTRFIEIRKLVNPSPEALRPFLEDDTTNITAYVRIVEDETGVLWHNLNNYDSKVETGFVGLKNQGATCYLNSLLQSLYVTNAFRKAIYEIPTENDEDILNSAYTLQRLFYQLQTSDQAVSTLELTKSFGWDTKQVFEQQDVQELSRKLMERMEEKMKGTKAEKVLPDMFSGKIKTYISCINVDYESSRIEDFWDIQLNVSGNKNLEESFKDYIQVEKLEGDNQYYAGEEHKLQDAKKGVIFTSFPDVLHLQLKRFEYDFERDALMKINDRHEFPEEFDAAPYLSEDAEKTDESWEYQLHGVLVHSGVLDAGHYYAFLKPNKDGWFYRFDDDKVVKSTLRDVLEENYGGAHPLPTNRRGSPIRKHPVMRMNSAYMLVYIRKSRLDRVLCPVTQADIPQHIQTRYQEEVELKEARRKEREEAHLYMTIKYATLETFKKHDGIDLSDFDLSKSENPGVPKVKRVLRTMSLSDLRDEFSKEMGVSSHKIRLWQMVNRQNKTIRPDTPIVDLGQTVDEAWSRSANQREQSMRLFVEVAETTGDKDEPIWPNFNSQNGVLIKGSVIFLMLKCFDTASQTLRGVGHVYMEKNKKLEDLIPQIGKIMGWPESLQSPERVLMWEEIKPTMIEPLKVKSTLHSAELVDGDIICFQLAPTAKSSSQEEPRKPSNESGNGNGYLEKFETANQYYDFLCNKRTLQFVPHPTRCDELQYPDFSLTISSKIPYEKLAERIGHHLGVAATHLRLWTINPTTGNPKVVIRRTGNTTLQSILIPNNYGHFNAPHRTDALYFEVLEISLAEMETKKSVRTVWLSEGVSKEEPVDVLLNKNGLVQDLIDALIKKLNLKSEEEAGPLRIYEVNNFKLYRELGRDVPAMTMNEYTTAYVERIPEEEVGLADDEKRYINAFHFHSEPSRVHGDEPFVETRKRLEKRTGFKGKSFEKIKFAMVERIRFTSPVYLSDDDVLYSLASVAKDDCLGLDHPDRSRMQRGGGDLFLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEG4</accession>
    <name>A0ABR3ZEG4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_001752</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000029">
        <property type="protein sequence ID" value="KAL1898749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785:SF4">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="468"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="543"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="734"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="782"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="992"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1627"/>
            <end position="1652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="39"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="79"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="135"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="160"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="240"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="255"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="302"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="327"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="403"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="543"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="558"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="573"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="586"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="633"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="735"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="782"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1006"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1031"/>
            <end position="1047"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1652" mass="181391" checksum="29D39E4FB1C9DF59" modified="2025-10-08" version="1">MDIGLPPSKRVCLESSNNLPWPSGSQSHARSRPSLSPAHHQPPQTISSSSSTSHPPPSHSHSHSHSHPHPHSHPHHPHSTPIQHSSSHQHLPPPPPHHNHGHPHSITSAAHHPQQQPPTSSSQAQYYHSSRQLEQSPGPQQPSHQQSHSASPSNSGPSHHTPPPAQGVPPLHPGPLSLSTHLNSATSPHGLSGQHSSQSQYQSQPVHPHHVTPLGTSSHHIPSPIKSESRQPPKLVGHQHHSDDSRSSAHRDLSQKPSLSPSSQQQQQQQSQQPPSNQGHHHQQPSHQYTAIKDTPHRSSAPPMPPTAPQYIPPHFQDDRGQPPQPQQQSQQPVQMQQPPSSQQQQSQSQMHLQQSQQQPQRMDSMPPPTPVTGPTQSLPGVGAMQPATMPPHMAPYEDPRRQQQPSFHGHQPGPPGPHHDAYRSSHQAFAPQNPMIHPMPYPESYAPEFTVQSTVTGKRKANRASQACDSCRTLKAKCDETKPCKNCKEKGLECKYRDPVPKAADKVQTDILEGIQSIRDMITSMSEKATKTDKELRIIKKYLTRRDPGIDFKKEDDQDNDLMELDETAPPGRRESEHRLDEPHSSTQPNARRNGQSEPAPTTRHLTNEMMSTVKIRPSPPPPSLDPKLEGPTDDENNTSQDDEVEAEPGPVVRPGEPSIPPDHTTGAGHLLDWPAIKEIVADILPEVKVKFTSEYPIRQEEARGILRIHGRGEGRDTGVPSNRNNIPVAIASGDQNDNSSLNAGTPNPGVNSNGNTVTKSYSAGNANRNLGISVSINTNTNASTSTPGNSSAIDQGSFEYDDGDYELDSPNDDRWGYAGPPSPMNSFDGSHLTPRSPNAHILGSMDLEPETMVKMACSFIENILNMHPIVHVTEIRMMMQVFLDTLPKVPSSAHHVAQSIEDRSMANTPTGTESVSGGTKRKRVDQEAVMGGKPIRFHLEVPIQPRYGRPARTISNGLVLVILALGKICLSRDYIHDFVPGDVAGPVTATSPSITRNDHLSGAGCQQSSPSEASSDHRAAGSPANGSFRRASAATPAAKANTPPTRNMDVIPGLDYFAMALDIIGSQMGGNTLKHVQANVFAGLYFGQLGRVIESHAYISAGSTILLNIMRPSFNRMRELKAGSKFPTKLRDNQLIFTFWTCLQLESDIVAELPRQQSGILAYDGTLPYPNLILITDPELGPFSDTVFESYMAQLYLRRHLNQIHRMFYGPNAKPALDPTTDFCDVKTAQSRVGDMLWVGPNFKFDEDDPPAGDILTARLRAKYWGAQVITYRPFVKQILDFGVKLRRGQAYHAVNEFRPDIQAPTIHPKTSSYEAIDEQIKIYAQRGIRALVESTQAFHNLGDERPIITNVFGTAHAQWGNMLVLAACYRDSFLSKHVDPENLLILMDKTLAFLHQSACSTSALAIDRRILKHVRHMIFRDAPPTSRETILATRKMNLAVMNASTHRRHDWMPKESATSERPPTGQGFVMFSGFDGSVRILEPSQINGGRLFMDGNQIMDGDHSLNGSLTMNGSQFLNASFLIDGSHFRDGIITMDGSQIIINSQNIDDGQMMSVEQIMNPNVMMNNNMDMGGNMNMNGSMDMGNRQMPNGQIMNVNPNMNINSAMSMSPSMGVNMSINSHPHTSMNADPNMMPMGSLGQGMHHSFGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF91</accession>
    <name>A0ABR3ZF91_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001632</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000027">
        <property type="protein sequence ID" value="KAL1898972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="398" mass="42960" checksum="B07C20E3FE4E5C08" modified="2025-10-08" version="1">MSRNLLRPAYGLTRAEFHNQLSVRSRALSTTTSCLDDISRSSPPHKTSSTSAPRLPRSRVAASEISSMLRHEASQPPPGANQVDAGTAGNPQGGPPLGTRVVNVRSLPRGRGGLRLGGGVLGTVVRNPDGTVSVRRMPKPTAGGRSDDPRRQQNNGNSEGIFRSRGGARTGRGRGGMGSGGRGGKAGSGGRAGQHGKSRDKRPMNQYHAMAEEIDWYAPYTKEELQVLAERVPAAPARVTETFVPELGIDELLEYAPALATDSNVLGKAATVRQTLKTIAGGPVDPGHLAHPNMMAAKYDYRGVMYFEKLQTKELLEQRAKISIKMGPDDRLKDVLVRRTLKGQYEPIPAVPKSDVLQLTRNYHLKANTYHSTATDKFQAKLEEVLAKAKPKQPARST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFC3</accession>
    <name>A0ABR3ZFC3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tropomyosin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TPM2</name>
        <name evidence="3" type="ORF">Cpir12675_001439</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000022">
        <property type="protein sequence ID" value="KAL1899403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000533">
        <property type="entry name" value="Tropomyosin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19269">
        <property type="entry name" value="TROPOMYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00261">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="161" mass="18751" checksum="97192CAB754DC636" modified="2025-10-08" version="1">MDRIKEKMNQLRLEADESAAKVEELQTKVKTLEQESLAKEQEITSLQHKNGVLEGDVEKLEEAVKDHKKSAEEGSSHSTQNEALQRRLQLLEEEAEEADKTLREANEKLRQTDVKAGHFERKVQALEVERDQWESKYEEMAKKYAEVQKDLEDFQREIGNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFU2</accession>
    <name>A0ABR3ZFU2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 14">Phosphoglycerate kinase</fullName>
            <ecNumber evidence="5 14">2.7.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">PGK1</name>
        <name evidence="16" type="ORF">Cpir12675_001608</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:14801"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the phosphoglycerate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.3" evidence="5 14"/>
    <dbReference type="EMBL" id="JAWDJO010000026">
        <property type="protein sequence ID" value="KAL1899052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004618">
        <property type="term" value="F:phosphoglycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00318">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1260">
        <property type="entry name" value="Phosphoglycerate kinase, N-terminal domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00145">
        <property type="entry name" value="Phosphoglyc_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001576">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015911">
        <property type="entry name" value="Phosphoglycerate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015824">
        <property type="entry name" value="Phosphoglycerate_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036043">
        <property type="entry name" value="Phosphoglycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406">
        <property type="entry name" value="PHOSPHOGLYCERATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406:SF0">
        <property type="entry name" value="PHOSPHOGLYCERATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00162">
        <property type="entry name" value="PGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000724">
        <property type="entry name" value="Pgk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00477">
        <property type="entry name" value="PHGLYCKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53748">
        <property type="entry name" value="Phosphoglycerate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00111">
        <property type="entry name" value="PGLYCERATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="10 14 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14 16" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1899052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="417" mass="44089" checksum="1203CABCFA76F683" modified="2025-10-08" version="1">MSLSSKLSITDVDLKGKRVLIRVDFNVPLDSNKKITNNQRIAGAVPTIKYAIDNGAKAVVLMSHLGRPNGQVNEKYSLKPVVPELEALLGKSVTLAPASVGPEVEALVNKADNGEIVLLENLRFYIEEEGSAKDKDGNKTKADPAKVAEFRKGLTALGDIFVNDAFGTAHRAHSSMVGVDLPQKAAGFLMKKELDYFAKALENPQRPFLAILGGAKVSDKIQLIDNLLDKVNTLIVCGGMAFTFKKALNNMSIGTSLFDEAGSKKVASLMDKAKKNNVKVVLPVDFITADDFSPTANTGSATDAEGIPDNWMGLDCGPESIKLFKKTIDESSTILWNGPCGVFEMEKFASGTKSTLDSAVAACEAGKIVIIGGGDTATVAAKYGVESKLSHVSTGGGASLELLEGKALPGVVTLSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH41</accession>
    <name>A0ABR3ZH41_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Mediator of RNA polymerase II transcription subunit 13</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Mediator complex subunit 13</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Cpir12675_001482</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 11">Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the SRB8-11 complex, which itself associates with the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the Mediator complex subunit 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000023">
        <property type="protein sequence ID" value="KAL1899366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009401">
        <property type="entry name" value="Med13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051139">
        <property type="entry name" value="Mediator_complx_sub13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021643">
        <property type="entry name" value="Mediator_Med13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041285">
        <property type="entry name" value="MID_MedPIWI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48249">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48249:SF3">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06333">
        <property type="entry name" value="Med13_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11597">
        <property type="entry name" value="Med13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18296">
        <property type="entry name" value="MID_MedPIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0010">Activator</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0678">Repressor</keyword>
    <keyword evidence="7 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 11" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="326"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Mediator complex subunit Med13 N-terminal" evidence="15">
        <location>
            <begin position="137"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="MID" evidence="16">
        <location>
            <begin position="1183"/>
            <end position="1356"/>
        </location>
    </feature>
    <feature type="domain" description="Mediator complex subunit Med13 C-terminal" evidence="14">
        <location>
            <begin position="1365"/>
            <end position="1670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="95"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="236"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="497"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="715"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="933"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1113"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1526"/>
            <end position="1563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="245"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="497"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="533"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="715"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="768"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="933"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="968"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1113"/>
            <end position="1125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1526"/>
            <end position="1538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1549"/>
            <end position="1563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF06333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF11597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF18296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1899366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1681" mass="182250" checksum="3FB2F31240794F01" modified="2025-10-08" version="1">MSSNTFPLGSQDDSTSNSTFDGTEAGASGNSSSNGGISTGGMIAIIVFVVIATIIGIASSVIFFIAKKNEWKFRESMRKSARRVVNALTPRRSEFPKSVKTGKLPSSREQPFHNNFDEIPPTPRLRPEDLEKGLHEDNIASINYRLFSLVPESKRTQGITAQGLEKSARDAGHIVLFDSRRRALWHFQTGHKDSKPLQPQQAALTPLESLEFSGFSLSLLGLGSYEPSSLAKSRLGPSAAVGSAQQQQQQQQTQDLSNAKSSDSPSLSISAFEAHPLFITALQGTLNTAFAWHVGAIPLNDRTLLIPSDKSSIYDSQASSMATATIQAYLTTAGALLVSISVTVHEGLRLLDKAMTYNHSIADCAVVLAPFGYPGRLRSPDGGIDALLAHTPYTPAFKQPDNKTSKWRLMISTLLRVRGIPPSVIDNAPWVDIQLGPSEPSDPKGLGRQGYMVQWPLKLCVRRSMVCLPPQPLEDEENDYDALNIAKSWFQEAPARAEKVARRKADREAQTSMDSDSKHGSQHNLQLTHQMHHQQGTSQTQQLQLQQSHSQSSHQILGLSAQSPLNNAIPRPGLTSNNAMYPTPPDGIQGQTVGLLTLAEDALSSPANGSSTVAIAGSSTTAMDLWTSGPSMSIGGFNGSAVEANAKILGDSSGGGIEIADVHLNFFDDKTLDSTDGVSGAFSPIQSTSRRFSHIGQMQPPPLPHQTQFQLQNSNLSCSNLGSGSHLPTPSMPPPSDFSSIKKQPLDSETPVFTKPELRHARSMGDNMRQNASQGRSRSVSFLQSPGNRLKRGASPFGPDAVYKRLRAVVPQAALPLHPATVRKGNVFDKVSFDSSLPAVNSKYAEGGIFSVDRKPFKRSFSFDTSAPPTTGYLRTHGKHRKVSKPYPFVAASNAQSATCHTNNNSLVLHVTKAMENSSLTNSPTRLGGMEEELQSDADDVSDASDMDDTSMSSDELTSPIKINGPRRPGDELSARGTPGRDSEDTECNSAMEPGNLSRIPSPGWIMSRFLAESEPLPLYPQLSGEDLVAIAQVVTEQASTGILKIHTDAQKGLEPSSTQNLRRKSSLLARQAVQTLIKVFPKSFRSPAQLNLKSLADTQDLASLQQAQAQAHVQANAQANSQQQRGALRPGSQARETERPPLIFTIMPSHLEIRRAESRLSILPTAVTFWESLGLGPCKGTKDIRAVCLFPGYSGLSDDVSCFLDRLKILYESLKLGSFETLTSNPGIEDGLVVYDAGWNSATTFATVFPNISPSLAERSSAICDALEASTEVGKNFVVFFVYWPSNPATIIEACHTFYRLHEAYRLSLEATGKFPNNELVLQLIPVDALSAPLSVVTPQPSDLSRLCIETYDRCSIFNQPMPAPSILLDEPVQRSSIEFKTSAPSESILHENSSIHVAYAKSLDNRWISIAWTDSRGLQQQTASYCLIRKGVRGQGMQWNDIAQDIWQATIELMAVWKVCWRVVISKCGAMDPSEVEYWTQLAQNETKASFYLVLLAVDTSPALQLLPKPVQLSASVQSATYATPAGTPQASTPEVASTPRATADGPSTTPTPSTVDVTSDPDGDGVLIDVAEQTWGIVLSHRLNNSMMPARQNPAMASGYLVKRGGMRCEDPPAVLEVNLVWLDGVARGIDPMLREMLKQFRGLGTLARARGVTEQWDVRPWHIAAAEKGARTLYALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH76</accession>
    <name>A0ABR3ZH76_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cystathionine gamma-synthase</fullName>
            <ecNumber evidence="4">2.5.1.48</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">STR2</name>
        <name evidence="4" type="ORF">Cpir12675_001355</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.48" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000020">
        <property type="protein sequence ID" value="KAL1899677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003962">
        <property type="term" value="F:cystathionine gamma-synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051750">
        <property type="entry name" value="Trans-sulfuration_enzymes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42699">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42699:SF1">
        <property type="entry name" value="CYSTATHIONINE GAMMA-SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="178"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="178"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="212"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1899677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="611" mass="67279" checksum="E7E44B8E44227EE4" modified="2025-10-08" version="1">MPATYELGEPIPNAEHAVSVSLPTWESNIGYEEGKSWVVSKMMTGYPRFFIHKSIALLANGIVNLYGKSSQTAMLFPMHSSAQRCLEFITTVSLVPPPVSSLYIVDLVLDTTKPTAPVLSQLNPAISAVVMDEHLWSVAKQYWQHSGDGISSRRAEFSNALLQKGLFKVESQQSIAPVSATSSASSSAPCRGPRRYQTRQASNDKIDRTGRKSPGSASGGSSPKPAADESSQATESFHFLEERFGRNLDLSLVPCARSAIRRRIAGAVAETSTAGPSPIGNVRGVKNLHEDDVFLFPCGMNAIFNVHRALLTARGPLRSVNLGFSYVDTVKILQKFGPGCQFYGHGSEEELVDLETRLKSGERFLALFCEFPGNPLLTCPDLKRIRALADQYEFPIVIDETIGTFVNVEALKFADVVVSSLTKIFSGESNVTGGSAIFNPGSPMYKLLKSTISSQYEDTYWPEDIIFMERNSRDFRSRIFRANDNALALCDLLRSHHLVKYVFYPKYNTTKDNYEACRLPDGGYGSLLSIVFHDRNNAIAFYDALKTAKGPSLGTNFTLTSPYALLAHYQELDWASKYGVDPDMIRISVGLEDTKELISTFQETLGILGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHP3</accession>
    <name>A0ABR3ZHP3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">COP9 signalosome complex subunit 3 N-terminal helical repeats domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001264</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000019">
        <property type="protein sequence ID" value="KAL1899684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055089">
        <property type="entry name" value="COP9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050756">
        <property type="entry name" value="CSN3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10758">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10758:SF1">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22788">
        <property type="entry name" value="COP9_hel_rpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="COP9 signalosome complex subunit 3 N-terminal helical repeats" evidence="2">
        <location>
            <begin position="209"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="488" mass="54405" checksum="445C3630C134AF91" modified="2025-10-08" version="1">MEELIRQLQSFPLTNNIPLSDEQYDSSIKSHIRQLSRAPIDQATSDLANIQQLLNAIKALDPAVHSASFGLVLEAALRKPKSSAEFPIASELLKFTALFDPIQIRYIGSSLVNILDTILDLDIFSAPIATDAVATALRRLDPEGTYLNSTRIRLAKVAYQACTLDPVMPLISLTPLYFPCTAYPPAPHLCSRVLTPPEYMSGLSKPLLPQDILEYDMTCGLIFCAQRKWKAARSAFARCVTHPSKSGDVSKIAVEAFKRWILASLIVLGSVNRDNVPNPCTHLLRKALPSFAQPYLDLAEAFSKDYRSLQSKIDSHSAIWPQDNNLGLVNMVISYYPKWKIGQLRSIYTKCSITEVQESLSKDMLDFAPNFSQIIAITEEMVSENMLAARVVAAEDDIPDHVVFTEPSKAKSSAELKKQIDECMHNIRTLQQASKDINTLIQIHPDHVQAFNDDINHRKVLMEADRVQPDFDMSMEDEDLMAGISTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJG1</accession>
    <name>A0ABR3ZJG1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">U2 small nuclear ribonucleoprotein A'</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">LEA1</name>
        <name evidence="8" type="ORF">Cpir12675_001041</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the U2 small nuclear ribonucleoprotein A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000014">
        <property type="protein sequence ID" value="KAL1900357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044640">
        <property type="entry name" value="RU2A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10552">
        <property type="entry name" value="U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10552:SF6">
        <property type="entry name" value="U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14580">
        <property type="entry name" value="LRR_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="246" mass="27712" checksum="27AFD57CFEFC5773" modified="2025-10-08" version="1">MRLTPDLIKSSLSYLNPLKERELDLRGHRIPNIENIGVAGPHDSIDFTDNDIQTLGNFPLSPRLTTLLLARNRISSIQPTVANSIPSLRSLVLASNNLQQLADIEPLGGLKLLTHLTLVDNPITKHEHYRYWVVWKCPSVRFLDYQKVKQAERDRAVQLFGTEDEPTALTTEILGNRSTAPSASSEDTSQTSKLTRMKLTEKENLRLQDMIKNATTLQEIIRLEKILSEGRLPPGFHLEEDDVMAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJP8</accession>
    <name>A0ABR3ZJP8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="487"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="162"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="347"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="514" mass="55512" checksum="EB53F125A551DBF9" modified="2025-10-08" version="1">MEDQFGGRTDDDLFYDDFEPVDGQVIVMPDIPLELAAAFGKKSQGLLATPKPELVSSEDSNLASKNMPSQKGKISCLDPDASVTPPTSSPAPLRGGLANSRFAPKANELEETTSKPNAPADAPKQKNNRIKAPKAAKLRDAASVPEVPKFMPPKPETLAKRSTVSETPPSSKSKSAESKHTSTKSGDATAKPHQPQDGNRPKQTGKNLQSDQSTARKDKGQLSVSRKPMDNTRIQSGANPRTKMTEEEVTAKMDQMRLKNAETVKKFEAAEKDETRHAVAVANDEAETQRRRKIEAEERKKMENERQKNRDKKLKSFKDNDTPWDAPKPSREPRESHELREPNTVPHSGRGSSKISGKQGGGGIQGSMHGSAHNRNDDSIPKAKKENIDKRNKPADDLFPCLSGVSGVIAPKTLSGPSFAKAARAGAEAQAAATLSSEVENKKGNDRGSAKGISIQGDSVIISLPPTSSDKPVVAESEAWKPKALTPLPVLDVGNWGDEMEEYEAQQAQKSGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJR7</accession>
    <name>A0ABR3ZJR7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Glycylpeptide N-tetradecanoyltransferase</fullName>
            <ecNumber evidence="3 8">2.3.1.97</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">NMT1</name>
        <name evidence="13" type="ORF">Cpir12675_000903</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>N-terminal glycyl-[protein] + tetradecanoyl-CoA = N-tetradecanoylglycyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15521"/>
            <dbReference type="Rhea" id="RHEA-COMP:12666"/>
            <dbReference type="Rhea" id="RHEA-COMP:12667"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57385"/>
            <dbReference type="ChEBI" id="CHEBI:64723"/>
            <dbReference type="ChEBI" id="CHEBI:133050"/>
            <dbReference type="EC" id="2.3.1.97"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the NMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.97" evidence="3 8"/>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004379">
        <property type="term" value="F:glycylpeptide N-tetradecanoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000903">
        <property type="entry name" value="NMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022677">
        <property type="entry name" value="NMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022676">
        <property type="entry name" value="NMT_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11377:SF5">
        <property type="entry name" value="GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11377">
        <property type="entry name" value="N-MYRISTOYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01233">
        <property type="entry name" value="NMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02799">
        <property type="entry name" value="NMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 13" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycylpeptide N-tetradecanoyltransferase N-terminal" evidence="11">
        <location>
            <begin position="177"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Glycylpeptide N-tetradecanoyltransferase C-terminal" evidence="12">
        <location>
            <begin position="349"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="59"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1900437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="567" mass="63477" checksum="856D3866EC3D654F" modified="2025-10-08" version="1">MSGLPENQPAPVSEADLAASGATAAEKQAEINNNSGSENDESDADAETHESTTNTDGAKKKKKRKNKKKKTTAGSSTGDAAPFLDAASVKAALEQLPPQQLEELMKLNPALVEEIKSGSTDGVNLAQMLRHLTLNDIMTGLASSGRNVKDMGSYKFWQTQPVPRLDEKTGPVEEGPLKPNQKVEDVPKEPAKLLDSFEWVEVDFTKEEELKEVHALLQGHYVEDTDSTLRFNYSLGMLRWAMMSPGWKKMWHVGVRAKPAGKLVAFISAIPVKVNVHGKQLLTSEVNFLVVHKKLRGKRLAPLLIKEITRRSNLEGIWQGLYTGGNVLPRPISTCRYYHRALNWTKLYEVGFSPLPFGQKPSQMVRKYALPDSTATPGLRPMKLADVDAVLGLFRKYLKRYELVPVYTREEFLHWFPMESPEGEEQFFWTYVVENDKKQITDFFSFYCLESSVINNPKHKAIRAAYLSYYATDVALTTPVDKDTLSKRLNLLMNDALILAKKHNFDVFNALSLMDNGLFLSQQKYGPGDGQLHYYLFNYLANPISGGVDKNNILDTENLSGIGLVML</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKM5</accession>
    <name>A0ABR3ZKM5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">rRNA-processing protein cgr1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CGR1_1</name>
        <name evidence="3" type="ORF">Cpir12675_000516</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SMP-30/CGR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013658">
        <property type="entry name" value="SGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005511">
        <property type="entry name" value="SMP-30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10907">
        <property type="entry name" value="REGUCALCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10907:SF47">
        <property type="entry name" value="REGUCALCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08450">
        <property type="entry name" value="SGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01790">
        <property type="entry name" value="SMP30FAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMP-30/Gluconolactonase/LRE-like region" evidence="2">
        <location>
            <begin position="18"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="298" mass="32807" checksum="140E025DE4EF695D" modified="2025-10-08" version="1">MHIWSVTDPFLPKLRCQLGEGPYYEPATDSVRFVDIKGNCLHTVYLGNKTLTTLPLATRVTVTADIAGVDPVQTILVGAKHGIAKLHRKTGELEYLAPLTEQQNERLRPNDGAVGPDGRFWLGYMTDFGQGDFRPEGGLVTYAQGQRERHLPSLPIKIPNTIGWSPDTSTMYFTHSSARQVFAFNYNVAQHSYSSQRIFYTHGGTGEPDGFRIDTEGNMWHAVYGEGKVLKIAPNGEVVGEVCLPTLNVTCVQFVGSKLFITTAADEDSGDEKSIEFGGAVFMVEVGAQGLNPFEYRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKX3</accession>
    <name>A0ABR3ZKX3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">UDP-galactose transporter Gms1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">gms1</name>
        <name evidence="7" type="ORF">Cpir12675_000933</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007271">
        <property type="entry name" value="Nuc_sug_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00803">
        <property type="entry name" value="nst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10231">
        <property type="entry name" value="NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04142">
        <property type="entry name" value="Nuc_sug_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005799">
        <property type="entry name" value="UDP-gal_transpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="203"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="333"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="387"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1900463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="427" mass="47056" checksum="E371E1DB8EDFD757" modified="2025-10-08" version="1">MKPSGDHKYFPSTAVFLNEIIKLSISLTFSLWEVSRTLAPSTPATTIFEQIYRSVFSADSWKLAIPALLYTFQNTLQYVALSNLDPVHYQILYQLKILATAIFSVALLGRSIALKRWLALIVLTIGVSIVSLPLNGNTQDALLFHDSSDHWFPRSVHELGQLTNGAGDAARELTRRSFEVVSSELAKRSATYEGIDDDIDTPIVMNASIGIVAVVIATVLSGLAGVYFEKVLKDSQPTVSVWTRNIQLSFFSLFPSFFIGIIYTDGPEIAKHGFFDGYNWAVWTVIVLQAVGGILASLCISYTDSIIKNFSTSVSIAISFVFSLWFFDIEATVPLLSGAVLVLASSWAYTLPDSKAIRRPTPLHVANLEKMMVDRLNTPRHLDPIKLNTNPMDSLDPTAGLSTSRPSSPMIGRIPSSARRGFDDHED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL34</accession>
    <name>A0ABR3ZL34_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_000763</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="294"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="116"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="261"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="557"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="88"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="559"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1900750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="636" mass="69485" checksum="542FA1EB6EDA64B9" modified="2025-10-08" version="1">MDATVDTKASRDHVSNTGSTMGPITQCDNITTSLGTIGSPKLLHSPQNHAAPHQLPQPQRPTCSAKFNYLRPETPSFQTQQPHRESEVYSNTAQPPRPNQGENTTAVFTNTIQELSRDDDQSYDITSPLSAPPSLPRSNSGSPSHSHSHTLATSDEVAAMMALRDLKETPPMSSNSSITSAKLVYCPEPPSALKLPAQEQLPPSSKPYRRQFKDALTRLVLSQASDSSGPKDIVSKRFEESRRLNEAVTVAVPAKRKRADLDEESDSVTAGAALQPLPKIPKPVPRKKKLQDGISRCSKCERQAYTQDNALVGCSRCDELWHQLCHSPEIGKETAGAPSGWKCSICLVEEDELARYNEARQEMLVSARRQTDVDALREKYFRSLPLGVSIPSPELVGFGPGETSEDVRFDYFSSLDRYDQLALLDFCDKLQPNLLAEVLATVSSRYPALALFGSPDWASRIVSGQSSPLSTPLPAATTTASTSNIAASILGAELPNNVRTPLLGSLRARLHMPLQKHLINTVALSRKPNRVYIPRRDLENLQKRESAANNRAALLAQRTPATPTLASSKSATPTDDEVDALPSTWPRPGHGMYANLLSETVDAKHLLDPHDTIAFQHFTIDQRGKLLPKMAVAALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLF3</accession>
    <name>A0ABR3ZLF3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47031">
        <property type="entry name" value="SAP DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47031:SF3">
        <property type="entry name" value="SAP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="478"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="531" mass="59505" checksum="306556EF90CC4790" modified="2025-10-08" version="1">MASIATTDMHTLNMAIDTNDASHVMSDIARNIQLQTPESASIPTDATGSGALMKEDSDYDMHEHPKTVALAKGALSPKRRRRSSSVEGEDKQPLKRLKDTQGNASDTSLGRIQTGSNLSPPLHGPTCALYVRNLLRSMSRDALRDHISGLVEGLQDGSLVDITEFYIDHSCTHAFIVFTHGFAADAVREALHGAIWPDKSHQRPLWVDFVAPERVPEWISMEETANRRNIKWEVEYTRDSTGTMGAQLVTMCDSAPANAPLGPKGQHSGNEPTINAPRGPRANYEDLDSQGIQLLNRGEGRNIVWTPLTGHALTTGTSNPPITYQMVSTSYVADRARNMRSYYFRNPKNGENDRAPHDSQDDIYRFSFAHSTVFINRGKENFAGIRHPRKEQRLRNSDQRKGQRQDQRHNGSARPGNTQPQADMLKNRQTNETSSMPPRKRQRNRRERRNGRERQFQTPAQPRPEAAAGPNTFGTQSNGPPNGAPNGARRRRRNRKFHGVADSYKPSYDQQESKDVNDRPPYDRGNNMNDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLK5</accession>
    <name>A0ABR3ZLK5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_000468</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052761">
        <property type="entry name" value="Fungal_Detox/Toxin_TFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47425">
        <property type="entry name" value="FARB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47425:SF2">
        <property type="entry name" value="FARB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="108"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="693"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="820"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="57"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="706"/>
            <end position="718"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1901598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="991" mass="107489" checksum="83607C5683A0B6D8" modified="2025-10-08" version="1">MNSSASTTSSPPSAVDPSTMTPQSANPSASPKPAPIMPSAGIESNTSQAPGALSARSPPQTSESPPTTSAPNSAIYAGKQRTGSMVGKDAAAVAAAAHKVTKRRAARACVSCRARKVRCDVVEGAPCGNCRWDNIECVVQESRRRKKNLSSVNGIPAPAPARRVSPAEPRQNQQNFANNENMIAARRAWTNLLRQAQNGANNNHISDNQCSSVALPAFVRPLPAKIGPDEITFLYAKGSLTLPSLKMQSALLQAYSEYVHPFMPLLDLHGFLKGINARNDPRGQVSLFLYQCAMFAATAFVDMEYLRECGFATRKAARKVFFLRARTLYDLDYEADRLILVQGLLLMTFWYESPDDQKDTWHWMGIATSLAHSIGLHRISSLMNVPPRKLGLYRRIWWSCFMRDQEIALGMRRPTRIKAGDFNVEMLQESDFDIRPVSDDNTAIPRDCRLMRDVRMQRDLADMAIAKAKLCVLVSHMLKIQYSVHTKGTVPMDSASMLFPNKTLDNADEVKEVDTSLNRWRVELPESCSNRPLTPFDVEDGKASIAVHRSLLHMIYYTTQSALHRPQFLGMQPAPAQPESNLHQAQEMARIRVRDAATQITRMATDLHELELDRFLPTTGVTIVLPAMIIHMLEMKHQNPQVRDRAIRGFKQCMDVMQTLRTCYAAAEYATGFLDAFLRKASIDLRAETQMSTMGSKSSHAAAADMSQSQGRGQSNGLFSFHTPPPETVPHFSKDMEQNIFSQPDFAADQSLSLSSMGSVMAPIVAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQAHTHDGLSTSSLAMASVPPIQTTSLAATSPPHTEHDADSALGSATPNDGSGVSWEDHHMDIDGSGVGSVAPTFEWSGVSTGEFDVDYWLQFPSEVGATDDIFGASGGTGTGKNGNAQQPLVSAAAVSAAAAAALAAMPVTDGSGDTLMWGSDPMVGVESGGMDGSELTDSLQMNFVTQSEVPRLSVKEKMATTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMV2</accession>
    <name>A0ABR3ZMV2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_000253</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bZIP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47416:SF8">
        <property type="entry name" value="BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTOR E-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47416">
        <property type="entry name" value="BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTOR F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="9">
        <location>
            <begin position="248"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="354"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="614"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="239"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="361"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="391"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1901745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="722" mass="76603" checksum="D32C385AEB5DFB32" modified="2025-10-08" version="1">MVSAMTPPYFDNGHVDTRYFTSEPDSLLNDNLMDSGLDSGIDMSPPLVSRKGSAMTNASLFSHKPEDSWGVDMQSIPSTTGSGGITSTAPTFFPADVTSQALMGAGSTGNWVVAPNSTVMGVDTVVMPQQFDAMENSPFGPMFSQPNMMTSNGTFGDIPMYNGIVAPGSVPNVAGNMNVDVNVSTIDALHAVSVGSKKSAMAQAVLHELRRGDGIRKKNARFDIPAERNLNNIDRLISQSTDEQEIKELKQQKRLLRNRQAALDSRQRKKMHTERLEDEKKQFTAIISDMEEDIAMLRKQCERLALEKQQIQDYLQSSFNMEKETLLREHTMETSRLRKQVAYLTDRVNTLGDEASKLRSSRNSGTNGTTALANGNSLGVFSPVDSNGDTSPSSSSSSSPSSTATSWNVVTVPASASTHSETFGIDPKNIKQEVMSSPQQQHVQQHVPMNQAELSSKGEEAAVDQIAVAGRGQNSLLFMLFLVGAYVISNDPSSAAMSILPPVSEDIRVTTASLLKGLFKEAGVETPFIGVSSASAYASGPSIVSSAATAATSPAAMGLADSWIQMLSAGSSDSNANVDMSMLGPLSSMLMVPSFKQERESMFTLSEVQFDNAIRRGPGSPVTGSTASRGRTPGSGALSVVGAGVCTGSPASASASVGADLRNLVGSLGVLRSLPNAAEACSRSLLQDLVPVALVRNFANLVTEAHNRCMLACDAVVRASKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMV3</accession>
    <name>A0ABR3ZMV3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="303" mass="34191" checksum="52E468A1C5452DA9" modified="2025-10-08" version="1">MPLFPRLQVFEIDDQEWFPPFLRTYVQSALTVGWNTALPFIHNQAPSQVTAKLLLRYLGPAINQYRFIDFCAGAGGPTPMIEANVNAALAARNQQRVPFVMTDLHPNVWGWTLAVNEANVRERQLHGAAGESMLGFEKQSVDAGDVPKQLLQRWTADGGKMFRLFNLAFHHFDDDLARRVLKNTVETSDGFAIFELQTRSISGFVTILMLGLGTLLLAPIYAIKWRSPAVLFFTYVIPVLPFVIIFDGFMSVIRTRTTEEVELLLRTCGAKDAEDGKWVIENGTEQFVWPFASVNYIMCTPQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMX0</accession>
    <name>A0ABR3ZMX0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">60S acidic ribosomal protein P2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RPP2B</name>
        <name evidence="7" type="ORF">Cpir12675_000149</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">P1 and P2 exist as dimers at the large ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein P1/P2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05833">
        <property type="entry name" value="Ribosomal_P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01478">
        <property type="entry name" value="Ribosomal_L12_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038716">
        <property type="entry name" value="P1/P2_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027534">
        <property type="entry name" value="Ribosomal_P1/P2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044076">
        <property type="entry name" value="Ribosomal_P2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21141">
        <property type="entry name" value="60S ACIDIC RIBOSOMAL PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21141:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045909991" evidence="6">
        <location>
            <begin position="18"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="63"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="67"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1902043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="108" mass="11118" checksum="493EB6F7E6E04611" modified="2025-10-08" version="1">MKFLAAYLLLNLAGVDAPSKEQIVKVLSSVGIESDDDRLQKLLSELEGKNISELIAEGSAKLSSVPSGGAAAASSGAAAGGAAEEAKEEAKEEEKEESDDDMGFGLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMZ5</accession>
    <name>A0ABR3ZMZ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000579</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="99" mass="11348" checksum="5D8D926FE2354FBB" modified="2025-10-08" version="1">MASKHGSRGSESLLLGYDENVDGRYILWNVNDEKVRATESVHFLNEKMQPRSPKREKQIDQADGDDVPEEPRDFGGKVLEREESADSDPVDKEMEMPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN36</accession>
    <name>A0ABR3ZN36_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Smr domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_000007</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14279">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003892">
        <property type="entry name" value="CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052772">
        <property type="entry name" value="Endo/PolyKinase_Domain-Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002625">
        <property type="entry name" value="Smr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036063">
        <property type="entry name" value="Smr_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46535">
        <property type="entry name" value="NEDD4-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46535:SF1">
        <property type="entry name" value="NEDD4-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02845">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160443">
        <property type="entry name" value="SMR domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51140">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50828">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CUE" evidence="3">
        <location>
            <begin position="107"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Smr" evidence="2">
        <location>
            <begin position="432"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="517" mass="57675" checksum="4FB5BD2A4A6EB949" modified="2025-10-08" version="1">MSESHKRKLSLLVDEFRSLIDEALIVSIASDFNLQKPKQFQQAKHTLLEISQNVDLEEASGFSPDAFGSANFLDNADTASQTMSHPSRYKSLGESTLTSSPSTSSDSEFGDTQALASVFPSIDPKAISHMLVKCGGNPDQAIDELIRYEERGEKYTLPRAIDDFFQPEDGDISPRRNKNKKKKTDPSFTKSEAERLGDITHLSSLLDCPIEELDQLYNDNQQSQTLTLISILETSKELGIEAKDPARLEMAKAFEQEYKHISPDYFPVVLQVCSPHIPDSSKQLLALLNKHYQKSKAQKQKHKQKLSVNYNLAPSETLDIIKQPTNSLLHTKRGVPSARFVSTWNEPTASINSCAATTYQEAKKMSNELHEKRIQTLRDAFKLARRSKGQPLLRSGIVVYLERAKSYEAPASDAMSRAADLLVSKGRTQYKIDLHGVTVDNAVRIAVEETRKWWQQEQTRARITRDPSQGFTIVTGKGLHSVGGQSRIRGPVISALQADGWTVTPEAGMCTVIGRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNA0</accession>
    <name>A0ABR3ZNA0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable glucan endo-1,3-beta-glucosidase eglC</fullName>
            <ecNumber evidence="5">3.2.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="20">Endo-1,3-beta-glucanase eglC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="21">Laminarinase eglC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">Cpir12675_000425</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24 25">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation and also function biosynthetically as a transglycosylase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Lipid-anchor</topology>
            <topology evidence="3">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
            <location evidence="2">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 22">Belongs to the glycosyl hydrolase 17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050732">
        <property type="entry name" value="Beta-glucan_modifiers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000490">
        <property type="entry name" value="Glyco_hydro_17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631:SF13">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-GLUCOSIDASE EGLC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00332">
        <property type="entry name" value="Glyco_hydro_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0134">Cell wall</keyword>
    <keyword evidence="17" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0964">Secreted</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="316"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="400"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="23">
        <location>
            <begin position="316"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="23">
        <location>
            <begin position="422"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="23">
        <location>
            <begin position="435"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00025152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00032134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00032906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="RuleBase" id="RU004335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAL1901556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="483" mass="49084" checksum="C80B5C1F51185447" modified="2025-10-08" version="1">MRSSTVASLAMAAVASAHTGFNYGALNQDGSVKSQNDFEADFKAASSLEGTDGSFNSARLYTMVQGGTDSDVISAIPAAVKTDTTLLLGLWASAGEAQFKKELTALKSAIDTYGDKLKDLVVGISIGSEDLYRLTPESKKSTPNPGAEPDTLVGYIKEVRDLIKGTALEGAKLGHVDTWTAWVNGSNSDVVNAVDWLGFDGYPYFQEAMENDIKNSKNLFDESMEKTRAAANGKPVWITETGWPVKGPDYNKGQASVENAEWYYQNVGCPLFGVENVWWYMLVEAGAEVEFGVAPSLGAAPYYNLTCSATTSSSSASATASATGKGKGSASSGTALPTGSSGTNFPGPHSTLVPVPGSKYNFSDTASAAPSGFVPVASAGAYSTGHLPILAGDAQPYYDSNKSPSLDSHGSYATGTASPTGGNSGSGSGSGSGSGSYASGGSSSATGSAGPSSSGPATITSSADRLTSAGAALAALAAAVAMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNC9</accession>
    <name>A0ABR3ZNC9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">homocitrate synthase</fullName>
            <ecNumber evidence="5">2.3.3.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">LYS21</name>
        <name evidence="16" type="ORF">Cpir12675_000096</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>acetyl-CoA + 2-oxoglutarate + H2O = (2R)-homocitrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12929"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58884"/>
            <dbReference type="EC" id="2.3.3.14"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:12930"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-alpha-aminoadipate from 2-oxoglutarate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.14" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004410">
        <property type="term" value="F:homocitrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07948">
        <property type="entry name" value="DRE_TIM_HCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02222">
        <property type="entry name" value="Homocitr_synth_fung_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050073">
        <property type="entry name" value="2-IPM_HCS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048253">
        <property type="entry name" value="DRE_TIM_HCS_fun_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011872">
        <property type="entry name" value="Homocitrate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054691">
        <property type="entry name" value="LeuA/HCS_post-cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02146">
        <property type="entry name" value="LysS_fung_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10277:SF48">
        <property type="entry name" value="HOMOCITRATE SYNTHASE, CYTOSOLIC ISOZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10277">
        <property type="entry name" value="HOMOCITRATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22617">
        <property type="entry name" value="HCS_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00815">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00816">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="15">
        <location>
            <begin position="43"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="435"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="445"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1902196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="465" mass="50833" checksum="3240D98E454843F3" modified="2025-10-08" version="1">MTSAPTEGHPGYTAVQTRENPHPKPARNPYEAIPDYLSNVHRYKIIESTLREGEQFANAYFDTAKKIEIAKALDEVGVDYIELTSPAASPQSRQDCEAICKLGLKAKILTHIRCNMDDARIAVETGVDGVDVVIGTSSYLMEHSHGKDMTYIKNTAIEVINFVKSKGIEIRFSSEDSFRSNLVDLLAIYSTVDQIGVNRVGIADTVGCAGPREVYDLVRTLRGVVSCDIETHFHNDTGCAVANAYTALQGGATHVDTSVLGIGERNGITPLGSLFARMVVAAPEYTKSKYNLKKLKEVEELVADAVSVNLPFNNPITGFCAFTHKAGIHAKAILNNPSTYEILNPADFGLTRYIHVASRLTGWNSIKDRAAQLDIEMTDSHYKECTAMIKKMADIRSIGLDDVDSIIHAYYKGLKEGKTMSSLDHVLDNMTDAERDTVVNGPGKRSADPADVVDAKKARTEETTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZND9</accession>
    <name>A0ABR3ZND9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000111</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021840">
        <property type="entry name" value="DUF3433"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37544:SF3">
        <property type="entry name" value="SPRAY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37544">
        <property type="entry name" value="SPRAY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11915">
        <property type="entry name" value="DUF3433"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="447"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="516"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="564"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="599"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="704"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="740"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="803"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="904"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="646"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="872"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="673"/>
            <end position="687"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1026" mass="112425" checksum="C8B5D4516295248C" modified="2025-10-08" version="1">MASNKPWDTGSSFPDEYGHGPDHNNGHGYGQSHGRISPEDGTAAGRNLAGRDEASASITSLADFDPFMMSMGVDVNDVSDVSDVNDVNDVNDIGDAASSHPPVSGSPTTTATTSPPPERPVLEPLSINRATYKALLSFSLSSKHQTIPEDDDFGDMAPMLGRTPAPGGVATDYEHPQHNLYNPYNTSTELRDLHNTTDEPRQCASVPIAAISTKLLYELQQQELNGMLTGGIGTGHGQPVTQLRGSDLGISLESPIRDSTTGNYETASSHYPEAAHNSTHYSADGSLLRSLSQRIGRNGTVRNGRMLSQEHTIRDFGQSEANRLGKPVEVLITEPFSSAKSPTTNVNVDISAITGPGSDTLDSSLMSQSTKRMTSSTLELLSTRSASTKIIYYPQPNWKPFTMGRKYISFLIVLTLGLTIGIEVTYKVNHGSDVARFTTPDKLPSGTYFVIKFLPIIVSVIYGVLWQLIDYDVKRLEPFYQLSLEGGALASRSLNIDYITDTNILMPIQAAKFGHYAVTFSSIAAMLSVSAVPTLAAASLYLYPNRAVRIKEPDATKSIRISPIYTHLLSATLLLCASCAVCLLIILNRRKSGLSTNPRGIAGIAAMAMVSHILMDFKDMDLASHADLHKRLKYQRYVLQNDALAPHPNNPSLGTGPAKKDSGSSAGKNNQEKEDDDSDYDAEADIETPDKHTTNAITENPHPLILRAAGCIPFIISIILFAGLIPGLLFSRMNVIMDQVPWLITLLAVMIKLGWNWLDKVVRLIEPYYILSKRRASPLTLTLDYTAMPFGYMPYRALRNGHWLVFMVGFGSVIVEMLTVLLTSLSHVEGQDLFTGHRNSSSQASSQSDDATRRLGLVLALVVRKVVKNGNGLRQDRDDDDDDGEEGSPFLQSLNSGQETRMSFFVSFSCALFILVYLATVATIVYARRRRPFMPRQPNTIASTLSYIHQSKMLYNFVGTTYMTTGEREKQLVSLGKTYGLGTFQGRDGQSHVGVDEEPLIGNYKHGLLVVVGQWNEPWNTMWDQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNY6</accession>
    <name>A0ABR3ZNY6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UBX domain-containing protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_000585</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in endoplasmic reticulum-associated protein degradation (ERAD). Acts as a platform to recruit both UBQLN1 and VCP to the ER during ERAD.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Directly interacts with VCP. Interacts with UBQLN1. Forms a complex with VCP and UBQLN1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01767">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46424">
        <property type="entry name" value="UBX DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46424:SF1">
        <property type="entry name" value="UBX DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23187">
        <property type="entry name" value="UBX7_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0834">Unfolded protein response</keyword>
    <feature type="domain" description="UBX" evidence="7">
        <location>
            <begin position="314"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="145"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="213"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="447"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="119"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="161"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="217"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="447"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="493"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="507"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="529"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00041575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00046062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="547" mass="58445" checksum="E8023F394FB4063B" modified="2025-10-08" version="1">MFYHGSLQEGIATAVQRNKTVVCFVTDEQEESTLWENEFLVDDEIADILHNEAIALRLAAGSEEAGYLAAIFPLPKTPTLVILKNGELKEYISAGTTKEVFMQRTLNSFGRKRKPTPEPATSSPTSEQSAASIIAAALSAASSPVIRASSSRGPSPPPPYSTSQLSQTQTQTMSFSESAPSNQDTQADTQPPTQSSSALSPARQILAERAARLTAQRAEKDRKARDSKPPLSSSSDPAPAPPASLTPQQSDHASSIHRQRAAQLAEKRRILQQIEDDKLARRQRATDRSAAKLTPGAVATALASAPSSSISRSSNDAMAALQVRLQDGTSLRSRFSRDTTLASDVRDWVSRERAAKGLPDSAYQFKLVLTPQPNRLLDGADEDKPLHAIGLTPSATLVLVSTSGASSAYANTAVGAGGPLSYILAFFAWISALLCTFLDIGGPARTNDSSTDQTGGADSTAVKATGVGRRETSGGAVAGRQLSTEDLHRRRQQASGSSSVASGSRIRGFEQQRMEPGEEERNAQRSEQHQLYNGNSTNFEPRPDDDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPI0</accession>
    <name>A0ABR3ZPI0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000052</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="240"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="205"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="424" mass="48031" checksum="55DF6E5AFD14BEF0" modified="2025-10-08" version="1">MIETPKNREGATPSPSRHLHKPGSHSKAQDGHKFATVHAYTQDVRRKILDMTIDQDTMMEDELAEKPKKRRVISPPTLASLSPATQKEALHDSPDLSLKFSPSRPLGTTNGNVTTGLSVSNKDKMLPGGFPKTDTEPLLPMVANEAAKNVNSETSCRGKKRGHSHLWRPDVEGDVLYDTDAMAQLEKQRKPRRNIAVRSYGGTIRARSNRGSSSGRPRAQRKKAWQTFVDLRPEYSEFVCEWQGCPAKLFNMDTMRRHVEIVHMRPIEIAVRFTPLGCFWGDCMLPRPCVEGKQLSGKKFNNMEELREHMEEAHMVPMSWHMGDGPMHDPDRNGLQVLRTGEPLPRYLFDAQGNQVTPDIRGQPVEDKASRKKRSKRLRQFFAQVNANIPSEDEDEDENNYSEEGTDGIARDKILDGTYRPKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ30</accession>
    <name>A0ABR3ZQ30_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytochrome c oxidase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">COX12</name>
        <name evidence="6" type="ORF">Cpir12675_000101</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome c oxidase subunit 6B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00926">
        <property type="entry name" value="Cyt_c_Oxidase_VIb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.140">
        <property type="entry name" value="Cytochrome c oxidase, subunit VIb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048280">
        <property type="entry name" value="COX6B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036549">
        <property type="entry name" value="CX6/COA6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003213">
        <property type="entry name" value="Cyt_c_oxidase_su6B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46281:SF8">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 12, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46281">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02297">
        <property type="entry name" value="COX6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000278">
        <property type="entry name" value="Cyt_c_oxidase_6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47694">
        <property type="entry name" value="Cytochrome c oxidase subunit h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="86" mass="10162" checksum="5C522548F74ACC75" modified="2025-10-08" version="1">MSDSEDQVTKPFKFVTGVDARFPNTNQTKHCWQNYVDYHKCINAKGEDFAPCRQFFLAYRSLCPSSWYSRWDEQREGGTFPVRLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQR4</accession>
    <name>A0ABR3ZQR4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PUM-HD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_000058</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07920">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
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        <property type="entry name" value="ARM-type_fold"/>
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    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033712">
        <property type="entry name" value="Pumilio_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537:SF13">
        <property type="entry name" value="PUMILIO HOMOLOGY DOMAIN FAMILY MEMBER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537">
        <property type="entry name" value="RNA BINDING PROTEIN PUMILIO-RELATED"/>
        <property type="match status" value="1"/>
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    <dbReference type="Pfam" id="PF00806">
        <property type="entry name" value="PUF"/>
        <property type="match status" value="8"/>
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    <dbReference type="SMART" id="SM00025">
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        <property type="match status" value="8"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PUM"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
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        <location>
            <begin position="624"/>
            <end position="966"/>
        </location>
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        <location>
            <begin position="650"/>
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        </location>
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    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="686"/>
            <end position="721"/>
        </location>
    </feature>
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        <location>
            <begin position="722"/>
            <end position="758"/>
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    </feature>
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        <location>
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    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="795"/>
            <end position="830"/>
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    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="831"/>
            <end position="867"/>
        </location>
    </feature>
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    <feature type="region of interest" description="Disordered" evidence="5">
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    </evidence>
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    </evidence>
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    </evidence>
    <sequence length="1111" mass="118715" checksum="EF5F573CBA578758" modified="2025-10-08" version="1">MPLPQPAATLDQRTSGSDSGPGPGFSTVNSNSNNAYSNHTPTVASTDPAITPASTISPLSTTLPHRFANPLTRAPSSATNTASSPSSIAASHTTTPTTTPTTTTTMNSLSITRALDGSQQQPDYSIAYQKVQLIEKKRAEYERLREQRRRFEAEMQRLDESQRREELELAQLTEEVHQLNGNQSEPTTPPHERYDSAIFPGFMARPNRYSISNVASPPGYYSRLARASLLQSHHQGLGLQRTITWDDPAATFRSVPVSRRNSDDEEREDATIGGGLGLGGSSSISGRYDAMSFRPTSTRTNRYSMPSASTGQSHARMLASDMDGLDQANTARFLFGNETTSNSHLESEYPREPANPGIEIAPSKPTTANESLGTGDWGFLSRTRSSFGAPSPIGPSSMPNSFRRSLDLKFLTENSVADSSLGNPTPISPPNGAIASPVGNMSGSYTPTDTPSAKPTSSSLFNPMSRLGGTMNSRSNSQLGADSLPLPRDQMNSASTGSASYHGMSSLHVGAAPFGPSAGGQASPQSAVSNGHPFFPTSTSFNPAPGSQPAANGLMMPMLGMGLQNMSINAFQPNQQQQQSPVHHQQQQSFTPVHSNTQPHASSVQAPPTKAQASYPSSTHGRDSQARVIQSRRQQETDVNNKYNNLPLEAVIGQIYQLCKDQHGCRYLQRRLEEHNPDITHAIWTETNQHVVELMTDPFGNYLCQKLLESCSEEERTTLIRNASHEMVPIALNQHGTRALQKMIEFVHTDVQIALIVDALRFRVVELIQNINGNHVIQKCLNKLKPEDAQFIFDAVGHNCVDVGTHRHGCCVLQRCIDHANEKQQEWLIARITEDANVLVQDPYGNYVVQYIIDLNEPSYTEPMVVQFRDSIGPLSRHKFSSNVIEKCIRCASDVSKDMIVEELLNPAELERCLRDGFANYVVQTALDYATPAKKSALIDAIRPILPSIRSTPHGRRIGGRINNMDTRGMTSNDGTGGQTALQRSASNSGSTSGSGSGSGSSSTSSGSSSNTAHSTASGAQNQNQQPSVGSGSGAKAAGTIGSGISSTVTSGTATPRTAGAGGGLAYANGLGLGSSGNGSRMGGSRGLRGGNGASVSASTTTAASGNEDWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YCJ8</accession>
    <name>A0ABR3YCJ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome c oxidase subunit 6A mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_006957</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cytochrome c oxidase subunit 6A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000454">
        <property type="protein sequence ID" value="KAL1885992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR11504">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11504:SF0">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF81411">
        <property type="entry name" value="Mitochondrial cytochrome c oxidase subunit VIa"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="18"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
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            <begin position="22"/>
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    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
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        <source>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU004396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1885992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="117" mass="13248" checksum="47DEB88B23C0DBC8" modified="2025-10-08" version="1">MFSQVSRATASRIAQVSGRRFASSASASASASAKANAFNTERESIRKHAAETTRLWLKISLACIPVIGLTGINCYRLWNEHWEHWSHLPPLEERSEYPYQNIRTKNFPWGNGDQTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YDH1</accession>
    <name>A0ABR3YDH1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Retrotransposon gag domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006929</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000430">
        <property type="protein sequence ID" value="KAL1886016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005162">
        <property type="entry name" value="Retrotrans_gag_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03732">
        <property type="entry name" value="Retrotrans_gag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Retrotransposon gag" evidence="2">
        <location>
            <begin position="77"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1886016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="214" mass="24533" checksum="14A3BEED48CABE04" modified="2025-10-08" version="1">MRPRPALPDVAKYDGLDYHKFRIFMADINEKIAMDCEALGGDKGCLVYISSRLTGDAKKSIGPHMETFYTMKDPKKAMKDLHALLEQTFNDPAAQDRAHEDLHKLELEDLSIREYLALADRLMVRANSATLSDKTKIRTVKRGLSRFYKEKLASTKVYEKYEEYKRDLLVLDSSLGYSSREDEPTQTSKAPYKKGRPYTPTRNGNSSGDRRRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFF9</accession>
    <name>A0ABR3YFF9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Homeodomain superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CUP9</name>
        <name evidence="7" type="ORF">Cpir12675_006801</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000379">
        <property type="protein sequence ID" value="KAL1886967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008422">
        <property type="entry name" value="KN_HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050224">
        <property type="entry name" value="TALE_homeobox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11850">
        <property type="entry name" value="HOMEOBOX PROTEIN TRANSCRIPTION FACTORS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05920">
        <property type="entry name" value="Homeobox_KN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 4 7" id="KW-0371">Homeobox</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="6">
        <location>
            <begin position="272"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="4">
        <location>
            <begin position="274"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="343"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="53"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="164"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="348"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="362"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="372"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1886967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="381" mass="42150" checksum="5A401088217D1CFF" modified="2025-10-08" version="1">MSTLATPARPLQTSYPHQSLHLSRNMIQSPNESRDGASISLPSLNQMLPEFYSTPSPNNSDSRSPRAYLAPLTSPDYVHSPTSNKRRRASIEEDDAAERSSRVPRVYPSPITDAASAASRSPSMRAASWSATPAPGPTRSEPRAPLPPMSYPREPAAPHPHGPAPTHHAAGHGHAMPPHASTPAPAVSAPIPQHPYSTLSPREEQYMHHPAVAAPAAPHPHAHYQQRYTSVPPHHQYASAHMAHGHPHVGNGPAPYGYDHYQRFEGMTAADTKQRKRRGNLPKETTDKLRHWFMNHLNHPYPTENEKMELMRMTGLQMNQISNWFINARRRQLPNIMSTARNEAEARYNQTSGNKGSSVPLSDGDNNSSYGDDSHYKRTSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGN9</accession>
    <name>A0ABR3YGN9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006524</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000315">
        <property type="protein sequence ID" value="KAL1887498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="528" mass="58519" checksum="4739140DE05D40CF" modified="2025-10-08" version="1">MVFESCQISPPASTPTLQAITTRRGRKAAIRNTGDYKAGAKPSISSLILRSQSIDKDCGKHSPAGSETETQKSSSFPRKMEKHWYSYAGSCDLEMEDNSSDAFIKKEGMYLTDSGPLTPHAMDHCDPLDIKPAVFSIGFNSDLHDDMMWHQKSGAGVSLNADVKSHLIKGETNCHIGLFGRNSGSQLELGTASNTPTLYSQNSTDPDTPYTVIDSPCSSFDSNMGDFAGQDMTFTQSLDIGYSSMQDTSMLSAFSRNAHQSDRGPTISPNRMRITPVSSPPVLAPSTSSSCSFSYLLNEQTPDLTTEQADQYPVQGQNSYSQAASHHNTYDPSTLGGNATSAVSMPYGRKSLPELAPKIVPTQPSQPMESIASPFPAPEGSGYPQFPGLENISPTWSPTVREGRAYKVSRAQRRLQDAYLVQAKLSGMTYREIRLRGNFSEAESTLRGRFRTLTKNKEWRVRKPHWFPRDIDLLREGVEYFCDQRSIDQGKIPWKRVAEYILQNGGSYLFGNATCRKKWDEMMYYGMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGQ2</accession>
    <name>A0ABR3YGQ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_006845</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000391">
        <property type="protein sequence ID" value="KAL1886931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044956134" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="20"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="91"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1886931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="616" mass="66788" checksum="9C7FAA384880ED90" modified="2025-10-08" version="1">MRISTLLSALLYAGFPVAALPQPATPNPIEALNALKQDGAFNSFGAMDNHKATHEAVQSIVAQHKRDTAAGIPLSARALPTSQIKNGTTTIYGRVLGSTETFAGVPFAQPPVGDLRLRAPRAIDAYEPTINAAGIAAGCPQLFFSLESNTSAIFDVLGNVLTLPLLQAINGQEDCLTITVHRPTGIKAGDKLPVLFWIYGGAFQLGATNIYEGAPLISSALDADMPMIVVMPNYRVGGFGFLPGAEVKKAGVGNLGLLDQRLALQWVADNIEDFGGDPDKVTIWGESSGAISVFDQLALYDGDITYNNKPLFRGAIMNSGSITPVEDIDSAKAQRVYNKVVSKAGCDSSNDTLQCLREIDYETLLRATNSLPGVLSYSGVALPYLPRPDGLSLTVSPEKLVPGRKYAAVPMIIGDQEDEGTIFSLIMAGVNSNSDIATYLSSYMFTLIKALDIRPFVDIYGTASSEGSPFNTGIFNQLYPGFKRLASMLGDLVFTLTRRIFLTDAIAANPNVPAWSYLSSYFYGTPILGTFHGSDILAMWYGIPGGNVIHSMRKYYINFVHNLDPNVGLSGQQNWPKWNEGKKLMNFRNPSNRIIDDNFRQEAYEWMYANKDMLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHP2</accession>
    <name>A0ABR3YHP2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alpha box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_006609</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000334">
        <property type="protein sequence ID" value="KAL1887276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006856">
        <property type="entry name" value="MATalpha_HMGbox"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04769">
        <property type="entry name" value="MATalpha_HMGbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Alpha box" evidence="6">
        <location>
            <begin position="189"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="400"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="479"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="407"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="417"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="489"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1887276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="516" mass="56742" checksum="ADBAADFDBAD7FCB2" modified="2025-10-08" version="1">MDTNCGNNGKAVGKRTGPVRKAGIPNLISRLQHFDTLKGGPLPAPTPREPRVSLPAFSSLFADQASLPTPTAAWGLYGHELSIPASYGDLGPLPLPVAYMRRGLVPDNGYIWHELLTRSRSIIDEHQVHFNASSATFKRKDHYCSDPACYHYQASTAEQQLEASTAEQQLEASTAEQQLEAFTAEQQLEASTAAVAEGSPSAQEQSVPPNTYGYIRPAVTSFICFRVYYQSCLYFLPRNADVLKAIAKIWRGDPFHPHWAVIAQAFTLARDVIGTKAACLPEFVAMAVSILRLPLWSDYLQELGWVGTETQRNEIRFDQDLSMANRTKFTWHLSCKSSSENPKIYPSMVHLDLLCACIVRGYLKGLYVDILVRIAAQYSTQSTLGPSRIKALVEKEEANQEAIQNLSRRRRRRRSSRASSRVSNQGGQRNQGVQRNQGVQRNQGGQRRAQRRPRFNVRFVYLSAEDIIAGRTSVHTALGFDSTPSQGSAPVTPAAPAAPTTPVAPAATAAPAPIIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHU4</accession>
    <name>A0ABR3YHU4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GDS1 winged helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006488</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000309">
        <property type="protein sequence ID" value="KAL1887585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057511">
        <property type="entry name" value="WH_GDS1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25318">
        <property type="entry name" value="WHD_GDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GDS1 winged helix" evidence="2">
        <location>
            <begin position="115"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="412" mass="45071" checksum="D0A9C92AC506FFA6" modified="2025-10-08" version="1">MPYNTRRKSLSLPSLGIHVPMTLAEKAAAASRTKSSLSATRLASTSTPTSSSSSNRLRRSALLAHGEEPQAKRQKKFHKQMSRFDCTPPPSPSVEKSTIESGAESDDSLNLPTLDDVDDEVVRTSMKQLHASGNRPHLIKELATCLTQHLTILQQSTNPSAIVASRLSSFIKRPIWTPKSPCPIGKELESVHPRRTYFFLTGCPRQPLPEATTSLDNSSVGARARSLLSPEDSSDISASEEGGYDDLPCVKLYRARSPSPEVDLSSPEFDSADDLDNAENLGALSRPWLKCRRGRGPPPPLESDEHEFTQTATGLQKRKLIDPSLEVPSETESELAFVDDLPKYDLWANDTRPSVSAGSSLLSPNPKNQSPRASKKDNEGDHWAPLGVSVVSWDRIPETIDLDELDSLLESC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHV3</accession>
    <name>A0ABR3YHV3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Lysophosphatidic acid:oleoyl-CoA acyltransferase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">vps66</name>
        <name evidence="11" type="ORF">Cpir12675_006762</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000370">
        <property type="protein sequence ID" value="KAL1886999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23063:SF60">
        <property type="entry name" value="LYSOPHOSPHATIDIC ACID:OLEOYL-COA ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23063">
        <property type="entry name" value="PHOSPHOLIPID ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="10">
        <location>
            <begin position="105"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1886999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="308" mass="34107" checksum="2608E7057B38F97E" modified="2025-10-08" version="1">MERFTQFRDRGTGVSPFMPVKSKGSIFTKIFQSIAFLFRLPIFIAYSTVYFLVLQFLPLPQFLRKLLLWVLLAIPGIWWVDLQLDGVRRGTLSSQPASRVPRGGDVLAANFTSPVDAIYLSAVFDPVFTQSFPGTRKVQCISLLSAALRALSPVTLSPPDESALVDIADLQRKHRNRIILVFPECATTNGTAVLPLSPSVVSSKEASRIFPISLRYLPNNTTTPVPGSWGTFLFSLLCHSTIRIHVRMAEAVINTVPGEKSNEGPVAYDEEEVISKVCDALSRLGRSAKVGLTLKDKQAFTKSWYSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI50</accession>
    <name>A0ABR3YI50_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glycosyltransferase 2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_006361</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000287">
        <property type="protein sequence ID" value="KAL1887956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06421">
        <property type="entry name" value="CESA_CelA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050321">
        <property type="entry name" value="Glycosyltr_2/OpgH_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43867">
        <property type="entry name" value="CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43867:SF2">
        <property type="entry name" value="CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13632">
        <property type="entry name" value="Glyco_trans_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="264"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="568"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="644"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="696"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="745"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="809"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="9">
        <location>
            <begin position="405"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="47"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="59"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="127"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="148"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1887956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="827" mass="92355" checksum="7CEFC1226C4D7F2D" modified="2025-10-08" version="1">MLGNNSQQNQGYDPQQQRQAYEIDEFQNSPPPQAYYEENQVLGRSIAGNSRPFSPQNGQQQPEQMSPSQMPQGHSPIPQIAAPYQMGSSQANSSGDLMSPYGQVMPHNPDGQSGASSSWGPLWAPPGSSTTLRYSVQSSTMDTPYHSRPTTPTGRGRATPQGLAAKGEWGTSMQPPSQLSLAGLLPGKNPEAGQSADWSGHYNIVQLHERDDANIIKGFRRHIFKLTPLLILISILTYISYLSYRVYCMVDAQKTAGTVYSQAWVFVAIECCVAIPSISHNIWTMWSFKKRNRPMLRLEGEEVPFVDIFITCCGEDDDVVLDTVRAACEQDYPRDRFRVVILDDSKSASLEAGAQALALTYPNLYYMARVKIPGQPHHFKAGNLNYGLEQMHHLPGGAAPFMAALDADMIPEPFWLRAILPHMLRDPKMALACPPQLFYNTPPADPLAQSLDFFVHVVEPVKDSLGVAWCTGSGYIVRREALDDIGNFPLGSLAEDVATSTMMLGKGWHTAFIHEPLQFGTVPEDFGSHLKQRTRWAIGTIQTSIKLNFCLWGAAVEKMTFAQRFSGFLYAALSFFTIIVSISLFAVPIVLIMQKPLVAYANNDQLLWLMRGAMATVLTNRICELTMFAPAGYHTGQRLSRYQLWMAPYIAMCIIRSFILPSWLGGQTQAFKPTGSLSSALNEREHDSRKNMFIRLWAILINYMAVFHLVFVYFTLVGVTTTTFRCFAIETTTKAELRCMITHAFWPPVTFLFTVNSMWTPISYAIDPPSMPPRENLLDRDPKTGVAHPTAESKKIAFAGQAAWFEFEYTLTTAFTILVFAGSFWYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIX4</accession>
    <name>A0ABR3YIX4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="5">2.3.2.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Peroxin-10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="primary">PEX10</name>
        <name evidence="22" type="ORF">Cpir12675_006420</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the pex2/pex10/pex12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000297">
        <property type="protein sequence ID" value="KAL1887788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16527">
        <property type="entry name" value="RING-HC_PEX10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025654">
        <property type="entry name" value="PEX2/10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006845">
        <property type="entry name" value="Pex_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23350">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23350:SF0">
        <property type="entry name" value="PEROXISOME BIOGENESIS FACTOR 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04757">
        <property type="entry name" value="Pex2_Pex12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="7" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="14" id="KW-0653">Protein transport</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <keyword evidence="12" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <keyword evidence="11 19" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="21">
        <location>
            <begin position="407"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00041230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAL1887788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="463" mass="49186" checksum="F94EBF1F14165B18" modified="2025-10-08" version="1">MPFDTESTTTPASSSPPNAQTSLTSLTSPSAEASLLASASPLESQSRSDPISVILSNARSKAASLTTSPFPFAAAPDVIRAHQKDAYFQGHLASQISGLHRLLLGARSAHKWTTETKTAASLLYLSLTTLLGNRTLGEEYCDVVSLHAPTGTLPTLRRRAVYIASSVLLPYAVTKALPSMRARARAFIVSKLARLPPYTFKARVWRYLGTHLSTILSSAPAHAVALALFYFSGTYYETAKRVFGLRYVFTHNVAQTPDRAGYEVLGVLLVIQLAVSGWIHARQFITGSGDDADAEAALAAEVCAAQARSGLGSVSLGAGDGSSTPLANAPADLADILLGTASNSSTSASTTLALQIPAALTPITTNSSSVKLDISAITHTPLLNTPHYSLDDDKTMAYISGMQQRKCTLCLEALRDPAATQCGHVFCWTCISDWVKEKPECPLCRRAALVQHVLPLRAATIET</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJG0</accession>
    <name>A0ABR3YJG0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006222</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000267">
        <property type="protein sequence ID" value="KAL1888299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="113"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="281" mass="30073" checksum="AA82B9894BEEBE24" modified="2025-10-08" version="1">MLTSAVPRGLDAGLIALIIASTFGVFLCACRQIRRPYPTSRELNTYSGREPHFRNTDSPGADPVPPYEPPVFPLSTFFTPAPSYGPPASGHPHFPPTPSYRTSPSVIIGGQHSPTTSTSPPPQLSFSSSWGVPDTRLSSPFDLEGLQDENTLHYPQHQHQPSLDSNSHGPNPSSSQVTSSAGIASSLPGLFSDASRIPRPTQAHPRIHPHFETIVQPPITRASSLPTSAQRGASEKLGQPEVATIEGISKLRYSTDLAAQALTSRAVNVVQPDFLCKPDCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJG2</accession>
    <name>A0ABR3YJG2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL23m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MRP20</name>
        <name evidence="6" type="ORF">Cpir12675_006367</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000289">
        <property type="protein sequence ID" value="KAL1887921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_uL23-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12059:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL23M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12059">
        <property type="entry name" value="RIBOSOMAL PROTEIN L23-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="199"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="224" mass="25427" checksum="E03BC5557C773DD1" modified="2025-10-08" version="1">MAAVVRKTPGFKLGKKQLFLTNHTISMINRPNQAPNFATFKVPLRFTKFDLRDYLWNLYNVEVTKVRSFVAPGPVVNTLTENSQQRVRIHRGQSEKYMTVELAQPFAWPSLPGDLEPWNHRLWEARKAYSEEMAKQQMVTARNETIAPSKIKASSDRRLLAKQAAALLKGDAKWSNGEILDEKWETVLKAAEQDVPLEKVDEQSPVASEVTEIKGKHTGPKTSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJL3</accession>
    <name>A0ABR3YJL3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006196</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000264">
        <property type="protein sequence ID" value="KAL1888359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="446"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="620"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="810"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="848"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="655"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="716"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="940" mass="102577" checksum="D1B2C1CCBB06C8CB" modified="2025-10-08" version="1">MATQMEMAYQAPPSPTLTNPDMILPDMEYDQSTSDDRSDALMAWKNAQVGDMSFALPESQYFNLDLNIAGTMSPTTPIIYGNGTMLSDIGEVTEVESTVGRSSPPASPIVTARMTSRAALRAGALDAVVNSAAYQTIKAKARMAHERRGSNESTSTITTNEHRGLFEDFDDSISVDDTNFQGDDEESIAEYYSADPMSRNALLAPGKRNLMVDPNDEDRLSTISIGRRAEEILANAKRRLTSMEGNLNRARSSLYVGTESPIGSDSSATPSPTMKINYDIDPLSHPAEHSGPSRYGSDQSAFNDDTGTRRAASAFGAAGGYRHVVNPRNSNDVLRKHPNKRDSSESFQDIQMDDAISISSRRDSGQADSLLSPTQLQFSDRSITRSTSAMQVLDIKDQVKDLKGKVSALRDQARADSMKRRSLQSLRMNSPFTHAVVDQWYAEPKTAPIAETPDNEIKAEAEPKTQDENPPQTPTRDNSQNNVWLEETGIISDEEMSPVEFEHSNVQGDNIGDTNSVGSSKYENAERTMTPVNGRAATPTTGPDSLMLQDIIQHRLENDIDDDMRTEDGYEDAAVITDYESDSGDSMYHDARLPLSHEDREDAFDYEHFFLHSAMGTIRQQRLERERRGSFSSEDSVETTRGPALTQSLERRNSNESISTIASFETANEGRQSRLTRNNSSDSASGSGSGNGSGGRSSSVISKTKTRHVSHMSLDTFVSAQENRSSPTKSRRGISSFRTSTGSDVPRSVSAMSSSNTVMRGPMIRRPVSTSTFRHRPSTSSFDSTGTNRSFPLVSKSRLSLTLPCAVNGRAPSAGILTPRDSPNTEAEEEEDLASVSKRLMHGTAAAANHNAPAQASVNPSSKANDPRMSSTSTSMSLLQHDDQMLVEQLVASLGQCVLKLSEVSRTSADSRILRQRMAAARRLLEGLNEPRNCEPSSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKJ4</accession>
    <name>A0ABR3YKJ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000242">
        <property type="protein sequence ID" value="KAL1888846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="181" mass="20280" checksum="5105A6BAA5D5F63B" modified="2025-10-08" version="1">MAKGGFKGGDDSVDNDQKRKWDRSLRGLSGVSSISSMGEDSPSEDELCTKLICLATELRELRSKRKTGRATQFRIYKKKLKLLRRKVASALRAKSFQDVQNMRQSFEEGIVQDTKNKALRHELAGLMDEVYEGTEDAFGVLEASVAAHMREATEASERYWGSRRKEGVSWREGGPLGESTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKP3</accession>
    <name>A0ABR3YKP3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7729 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_006120</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000255">
        <property type="protein sequence ID" value="KAL1888575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056146">
        <property type="entry name" value="DUF7729"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39460:SF1">
        <property type="entry name" value="C6 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39460">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24855">
        <property type="entry name" value="DUF7729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045404634" description="DUF7729 domain-containing protein" evidence="2">
        <location>
            <begin position="35"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="393"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7729" evidence="3">
        <location>
            <begin position="156"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="416" mass="44554" checksum="FFF3475196F46ED7" modified="2025-10-08" version="1">MLFVRASAKLAPLSLSQTLWSAAFVALASQSTLASPVTASGPEITVPSSTVELPPFITPAAFDYHDYGDDTLLAVDTVRPIRIDGQWKLVDDVEWELRKRTVDDSSGSTSSSAIVSVAESSATATDLDKFATTSSTAILSATAAQLSTMTSGDFALPSPMDENLNYNFTTNGGKSCPAFLNSLLNDEQFTACYPISMLLKGSHSFFSAQRQLQTVVRVLDTSCDVDFDTCKAYLKQKALDLTGPKNCAEEYHNDASNIMMVYWGLIAYEPLYKATCIRDPETSMYCYANAVTNTSTTGNAYTYFMPLNSSFPATAEPSCNTCLQKTMAVFQSFTNDASQPVAYNYGPAAKIINNACGQGFVNQTSLKITLKNGTVPKANGTRSSAASGRMAPMPAVGTTMSTILLATLMGAAFAWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKP6</accession>
    <name>A0ABR3YKP6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_006338</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000284">
        <property type="protein sequence ID" value="KAL1888004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1888004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="150" mass="16720" checksum="B8C2E945DC834D9D" modified="2025-10-08" version="1">MPRKKIIDYERPGVQASVEMQTAAWLVTEENRQLRQLLLRFVYGKEIETYLEGGQVQTNKRQQRPGGAQMYCILPPETASVERPLPVDSLLPTLHRDPLQTECTVAASIPTDLHSSTYRDKAEPRSALSCTGPESCTVGNSRVFAFMGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL06</accession>
    <name>A0ABR3YL06_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Centrosomin N-terminal motif 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000249">
        <property type="protein sequence ID" value="KAL1888710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="102"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="256"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="373"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="682"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="865"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="184"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="263"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="281"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="373"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="429"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="701"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="723"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="738"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="865"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="893"/>
            <end position="911"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="939" mass="102198" checksum="16624612DC8A2520" modified="2025-10-08" version="1">MDSSPMLPGLERQRLTPHYTRSSTVSSLGRLPTPQSSNGSTHSMSSPQIPISNIAYRLSNTGSAKPVLVHSPRPSPLPREGTVEIRPSAMSTYLQEKLAKERKEGDFTARMTPDCSSPTEARIPGSPARISTPTQDRGAFQAIDNTPGKKGLGMGVKEMEVTVTTLHKQNFDLKLELYHRRERQQALESRLEGVESEKRQMEQMNDRLLEELEKRDKAVEEAVAMIVMLESQVENLLKERETIRKAESRIYENQRWTGDNYETPSRSRTPRQRPSIATDAPQFSDSQTLRSSEDRPLNRMPSFLSDLNETTENLRNVYLTGAKAGSIVNLPSLNEALSEVEAAEASIPEQLRSPSLSMLSESSFVSVYGAEKSGTQSNARSKTTDFGTPSQSFTLDRQHTPRLLGTPREPDRTLTPRGHRSPSAHSKVASLSSISGPMLDQNSPLQRLEQTYRLRGSSGSSNEQIAASTPVLRSSKALVQRKGKEDKRASLKEVLTELPNRSIHDSGMPPTPDTISTATLRRYQVENDTVDRSAIMLASSPIDMGNIQYIKYVGSNGSLGGVPLQTKIADDASSERSFQPPTVSDFPGRRDAFDTLFASQNLPRPHSAGASTILHHCDYADSDDEDARSLASSLDIWIREGGKPPRALGCETPDLLSLPYSSAHGWTPKAVYGAANGLMDPKTLFDTPPPGVPPPPHRRSSLNAKTGAGSSPSRPQTMATMAGKDRGGKARRDEAFRPSSQSGVPFTKNSGMSKNSPYPPPAQPQRQRGINNFWRRSLGSSGLVLNSSSATVDQTIGNDGGVSIKPHNEGTALPSETDAYGTAAWHKRHSLAPQDVRNSATPPPIARNRALSIDLRPEVEGCIVTANNNTKPTTPRTPINAQKHVFPPHSHSHGYSASVSAGNTPITPTSGPNGGSKKGWLSRFGRSNSISKSSKDREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL91</accession>
    <name>A0ABR3YL91_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Target of rapamycin complex 2 subunit bit61</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000235">
        <property type="protein sequence ID" value="KAL1888992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013745">
        <property type="entry name" value="Bit61/PRR5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32428">
        <property type="entry name" value="TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT BIT61-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32428:SF2">
        <property type="entry name" value="TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT BIT61-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08539">
        <property type="entry name" value="HbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="484"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="780"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="211"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="484"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="494"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="780"/>
            <end position="798"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="954" mass="100215" checksum="19CAE973037F63B8" modified="2025-10-08" version="1">MQPRRTSASQAPAATDSGNSSGATTGTGAGAGAGTGPLGTGPRPGMSTSTGVEDLAAATSRASPFSNSSRPIPTPQAQSQAQAHTQAYTQNDREELTIVTTRAASLDLPYPRSQTLYHQQPPQQPSATANHPSTPISAHSTLNFSRPSPLGRTPHDSLLLGSAASGLGSGGPPSTQSGSSSSTLNFPTINGPTPSNMPPGGQFSQSNSAAGHNPSNHNYNGNNLSASQIAAQAAVLHHRPSGGVHSRQRSQTVPAPGEDLTYLRGRTGPLSPPTVNLTESSAPRETPLGYNNGLLGSSAAAAAANAAFPRLNTNLAPSVIHPGSPMITTTSPHLQVHHPSQQFPPQPAVPEKKEKSRKLFSRPSKVNTKDTKERALPSPAKLGSAFSSALQRGNYSTTSLAPEVSGATTPGGLASSSAASLYSLANSSSVTIRPIEMPGSEKEKEKKHHFLSRQKNKIKDEYHLASSTSTAKSSTTNLYSFHQTTPVPTSSTFKGHHVIRKDKKTKDDKLDVKHVDPDTAAADLPPSVLANIHMDMQEAKLSSLSQLGPEDAWPYIRSKIIVVFEGEEVRVPIEDLNRIVLFHLQLCISRRAPTQLLEDLKELLRAGFMALDRAMRKTPEDRTIPELVEFWMFTFTVVLPYLQAVFLPLDLEFSGAGILLSTDQAREFWGAVAAIAEGSTTPALGLNIRGLVLTAYRDIVVLPRYDILKTIFSRLSLEFLPTSLASMALASPPPETATLSTSPPESSTSLGRLSTSASAAIFDPSLASFNSTSTTLFSEMGGSLSSSNNNNIASGSHSVGTRSRAISNVSYSSNISDGGIFRSYTPSTLHLNITSSLGAGTGLLASSAPGPGSALGSGISTSSGGGLGSLGSVREQNVEDSKQVTELVGRMLQCMSVLSSVGVGGTAARDEGSEKMLELSRLLKLNWLGRGRTGRNRRGLVGARVRRDTETSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLF8</accession>
    <name>A0ABR3YLF8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Long-chain fatty acid-CoA ligase</fullName>
            <ecNumber evidence="7">6.2.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">FAA4</name>
        <name evidence="7" type="ORF">Cpir12675_006062</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15421"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57560"/>
            <dbReference type="ChEBI" id="CHEBI:83139"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.3" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000248">
        <property type="protein sequence ID" value="KAL1888712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF83">
        <property type="entry name" value="ACYL-COA SYNTHETASE LONG-CHAIN, ISOFORM J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="6">
        <location>
            <begin position="107"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="691" mass="75130" checksum="260BF8990E3522D1" modified="2025-10-08" version="1">MSFSTGMAPLKQMGKPPYTIEVPGVAVEGETLPRRHPKAKDGLLRSPDDGVFTIFDLVERSAKLFAKNTITGQRKLIKMHKEVKKVPKVVDGEVTQVDKEWQYFELSPYSFITYAEHQKRYTQIGAGLRKLGANPGDKVHLFAATSSNWLTLAHACSSQSISIVTAYDSLGASGVEHTIVQSAPEIMYVDPHLLKVASGALEKATSIKTVIYNDNCIFAAGDEVEKFKASHPNLAVLSLEEVRQLGEENPVDAVPPKPEDIFCLMYTSGSTGVPKGVPITHEAACASVAGLYSCVEGTVTPNDTILAYLPLAHIFELVLENLVIFIGATMGYGSPRTLSDTLTRNSAGDMREFAPTILVGVPQIWETVRKGVTAKVEQSSPLIRSLFWGAINYKTWMTSHSMPGANLLDSVVFNKVRQMTGGRLRFIVNGASGISDSTKHFLSMVLAPMMAGYGLTETAAIGSLGSPIQYSPTAIGPIPASVEVKLVSIPELGYFTNKTPPQGEIYIRGYSVIKEYFQNPDETAKAITSDGWFKTGDIGEFDSVGHLKVIDRVKNLVKLAGGEYIALEKLESIYRGSQLVANIMVQGDSEHSRAIAVIMPNEINMKAKAKELGIVDEHIYSNSKMRSAVLKDLASIGRNTGLTSLELMAGVVICDEEWTPVNGLVTATQKVNRRAIKEKYAAEISECFKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLP5</accession>
    <name>A0ABR3YLP5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Calcium permeable stress-gated cation channel 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Cpir12675_006228</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CSC1 (TC 1.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000267">
        <property type="protein sequence ID" value="KAL1888304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032880">
        <property type="entry name" value="CSC1/OSCA1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022257">
        <property type="entry name" value="PHM7_ext"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF20">
        <property type="entry name" value="SPORULATION-SPECIFIC PROTEIN 75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12621">
        <property type="entry name" value="PHM7_ext"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13967">
        <property type="entry name" value="RSN1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="743"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="795"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="838"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="892"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="957"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1009"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1039"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like N-terminal transmembrane" evidence="11">
        <location>
            <begin position="60"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="12">
        <location>
            <begin position="250"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="12">
        <location>
            <begin position="629"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="9">
        <location>
            <begin position="741"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="domain" description="10TM putative phosphate transporter extracellular tail" evidence="10">
        <location>
            <begin position="1198"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="317"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="458"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="339"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="362"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="458"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="486"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1888304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1277" mass="143410" checksum="DB596221330DDE0D" modified="2025-10-08" version="1">MASPSLNGGPGPNFSKRLVHSYVSFVDYAIRPRDTSVSSADDVDGESGSAQKLSGISLNAFLTALVVSIIIFGVQISVFLLLRNRLARIFKPKTYLVPERERTEPPPRTPWGMVIALMSFKDREVINKCGLDAYFFLRYLKTLLVIFVPIAMVVIPILIPLNYVDGRGHDVNHRSKSNPFNNATSVTGLDTLAWGNIKPTHTSRYGVHLFLAICVVIWVCTVFYFEMRVYIKVRQDYLTSAEHRLRASATTILVNSIPSKWLSKEALRGLFDVFPGGIRNIWLNRDLSVLLAKVHEREAINKMLEGAETELIRMAKKNQMKQKAKEEKKLRKKQRRKGPTKEELANRRAQEDDEAQRRAETTEGTETQANATLANSDLDDAVTQARKRLTMTAEHVPGNSNKLTAGLSKVGKGVIGGVGKVGDGIVGGVGKAGAGIVGGVGKASNGLKLISHGVESTLDNTNGFTTIRTPAEEEPERSCSPQGQHTRNTSNSSSVGSSTEYNNYKPPARKPDNRASAYRVHYQEDDSPTAVYYNTVRKVDNLDDMYSKVKPHFWEFWKPPEGSYASPIPQTAESQDESQANVTGWRRLLWSFRLMSIDVPDIDYPEYLTNQKKEEAHGPAEWEKWVKRKHRPTHRLPNFTWTPGFLPGLPLINKKVDTIDWCRKELARLNMEIEEDQKRPERYPLLNSAFIQFNHQVAAHMACQSVIHHIPKQMAPRINEVSPRDVIWDNMAISWWQEWARSALVTVAVAAMIIFWTIPVAFTASLGQIDSLVIQFKWLSFLVANETMRKISKSLVGVLPALLLAILLILVPIILDFLATVKGAKTGAQKAEFVQRAYFIFLFFQVFLIVSIASFFAASADEIFANIQSLTKDPFKVLELLASNLPKSANYFFSYMILQAMSTSSGTLLQIGALAGWYLLARMFDSTARAKWSRNTTLSTINWGSFFPVYTNFACIALAYAVIAPLISLFAIITFSLLWIAQRYSMLYVTRFAVDTGGVLYPRAINQTFTGLYVMELCLAGLFFVVVDDNGNNTCTEHGVIILVVLCLTALFQIMMNRSFGPLLRYLPVTYEDEAVIRDEAFQRAQNKRLGLLDDEQQDHDDGDDSCPMLASSVQSQADEDIELTKVKRSMTDTINPVKRIGTWANDSRTGRALTLGKVRANTADYRRRQKARDMEAQKAIGDALFLGYHNEIEDLAPDERDVLVRYAFLHYALRARRPTVWLPRDDIGVSDDEIRQMQNLSDYIPASNASTALDSKARVVYGRNPPDFLEVDLINL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMN0</accession>
    <name>A0ABR3YMN0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000211">
        <property type="protein sequence ID" value="KAL1889599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="176"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="220" mass="23053" checksum="B1FB34FD95B94BBC" modified="2025-10-08" version="1">MNPQVPPYSFPAASYPPSSTGSYASSTSSSSFSSEGHIDLRPIQSQRTSIRLLRIFSGIDPILPPMRNGLSSRARNVLGDMDGSHRYHRRHRHHSSRTSSKHSRSSGSDYSSEESDSEAGGPTVYGNPGPGGVPGAAAMGGPQAPASAAPGDGNPMPSTSAKFPTRSPPSPETIRAQAQAQAKAQAQAKTQGPKVARYATFVPRVWRPGTPATDTDKSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN15</accession>
    <name>A0ABR3YN15_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005674</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000207">
        <property type="protein sequence ID" value="KAL1889696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="271" mass="30174" checksum="E157703C3FFBB78F" modified="2025-10-08" version="1">MNATTLMPGQRLLVRKRPRNSEDEGSDLANLPNAGLSEHRSKRPNCQPLPETAFESSISASIGFDFTSANITLATEPLFSKAEQFVHQQAQNNLASHIPTPIDASFPGQHRSWSGPGPAISCLNGSRKFSNEHESMTYQSTDDFTIPRTIGTDGSWSHTHQHLDRAGLPSPESSFDSSMQEDDNADVEMDYEQSPDREFPPQMQVPILQEPSSPHPETNSSPSWKGHNRSRHTVNSWTWQPGMKRSFSIGYCSDCEKCQMKAPGHFNHIVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN96</accession>
    <name>A0ABR3YN96_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein lifeguard 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_005633</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000203">
        <property type="protein sequence ID" value="KAL1889836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10429">
        <property type="entry name" value="GAAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006214">
        <property type="entry name" value="Bax_inhibitor_1-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291">
        <property type="entry name" value="BAX INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291:SF50">
        <property type="entry name" value="PROTEIN LIFEGUARD 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01027">
        <property type="entry name" value="Bax1-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="275" mass="30429" checksum="9F47B2E8B962E9BE" modified="2025-10-08" version="1">MSTAKYTKAPTVDPDECRTAPPSYQAAAGSSSTVSDGVFGTPRTSEDNIPDDFKFGGSVAEATIDIRNQFVRKVYAILTAQFIATAITSSLSFWSEGYKLWVQSHPGLVFVSMFAAIGFMAATYWKRKSYPMNLVLLSAFTLTEAYTISVIVSFYDIGLVVNATLITAGMFIFLTAFACQTTYDFTSWVPYISGLLWGLILFSFMYMFFPYSSTGELIYGGAAALIFSAYILIDTQMVLRKFHVEEEIAAAITLYLDLINLFLAILRILNSQNDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNJ6</accession>
    <name>A0ABR3YNJ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_005686</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000208">
        <property type="protein sequence ID" value="KAL1889682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002410">
        <property type="entry name" value="Peptidase_S33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF2">
        <property type="entry name" value="PROLYL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00793">
        <property type="entry name" value="PROAMNOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="83"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="478" mass="52784" checksum="D8700CF250FD67C1" modified="2025-10-08" version="1">MASAPSPAPGLIDYHIPVAIPSDEITTYRTGRIVVSELSFKVPLDYASNSSDTITLFARAAVQCDKPVAETSAKDAPLNSPKPWIVYLEGGPGFGCPSPLTHPIVTRMTEYRCLFLDYRGTGLSTPLSYETLQGKDNTERAAYLRLFRQDNIVRDLEAVRQYLFAGVPKGEKAQWSIFGQSFGGFVSMTYLSAYPKSLREVFLTGGLAPIGESPDAVYKATFLRAIDRNQAFYRKFPGDASKVHQICSFLEKQDGVALPEGGNLTVSRFLTLGISFGQHGGIDKVHGIITRACQDLEVFGFISKPSLSTIERETQFDLNIIYAVLHEAIYCDGPGSVSSWAAYRVGSEIRQFSWLKSNSMSAFSACDPPYFSAEMIFPSHFDTTPDMKSLFHVAEELATYSKWPHLYDLKRLANNTVPIYAASYVDDLYVDSALARNTAKNVGSCLVYETNAAYHNGLRAKADVIMDALQQLRMSTLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNN3</accession>
    <name>A0ABR3YNN3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein disulfide-isomerase</fullName>
            <ecNumber evidence="3">5.3.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_005746</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Catalyzes the rearrangement of -S-S- bonds in proteins.</text>
            <dbReference type="EC" id="5.3.4.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000213">
        <property type="protein sequence ID" value="KAL1889529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03002">
        <property type="entry name" value="PDI_a_MPD1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057305">
        <property type="entry name" value="Thioredox_PDIA6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815:SF3">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24541">
        <property type="entry name" value="Thioredox_PDIA6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046106703" description="protein disulfide-isomerase" evidence="8">
        <location>
            <begin position="23"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="9">
        <location>
            <begin position="13"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="250"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="258"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1889529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="420" mass="45887" checksum="484F8CFAE97DED90" modified="2025-10-08" version="1">MHHPTVLAAITALLCATPGAQAAFYPRNSPVMQLESKTYDQLITQSNYTSIVKFYAPWCGHCQSLKPAYEKAAQNLAGLANVAAINCDDDVNKGLCSSMGIQGFPTLKIVRPGKKRGRPIIEDYRGERSAGGIVNAVTMGINNHVIKVTDKDLDKFLESNPEQPRALLFTDKGVTSTLVKSLAIDFLSQMSIGQVRNKEKNAVEKYNIKKFPTLVLLPASGGDPIVYDGEIKKEPILDFLAQAATPNPDAFKIKSKTVPKDKKPPKDSAKDKVKAQEKETNEKPKPTEAALHLPTVLSTAQEIQESFLSSKSKTSLVFLGPETTTSIETIGKYLAAKHPAFPFYTLSGDSPALGPLRAALGVEQEENMVVVNYKRGWVSKYDGDFTQKSISDFMQAVVAGSWKREDLPEFDLGKGAHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNY8</accession>
    <name>A0ABR3YNY8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cytoplasmic dynein 1 light intermediate chain 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_005629</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000203">
        <property type="protein sequence ID" value="KAL1889832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008467">
        <property type="entry name" value="Dynein1_light_intermed_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022780">
        <property type="entry name" value="Dynein_light_int_chain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12688">
        <property type="entry name" value="DYNEIN LIGHT INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12688:SF0">
        <property type="entry name" value="DYNEIN LIGHT INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05783">
        <property type="entry name" value="DLIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0243">Dynein</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8" id="KW-0505">Motor protein</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="17"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="432"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="454"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1889832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="542" mass="58737" checksum="E1D305C3D057BD49" modified="2025-10-08" version="1">MTSGANANRMSTLTVASTTASDSGRGGLGSGNSNGNGNGSSSGNGDVKKDLWLSMLDTVATGKKLPEKNLLVLGGSPDSQREFLDSLSSGEQRWNVDRQSDAPPIANNFALGYTYYDVLEGDQEDTLARISLHLLSTPSPSFTSLLQPLLTPETIPDTLIVVLLDWSQPHLWLRQLREWILMLRQVLITLDDDCGNAMEQLMDEWRDRGRGGGSLNLDGTQANEDAGAALPLGPGEWEDGLGLPLCVVCQNADKMELLEKTHGWKEADFDQILQYLRTLLLRHGASLIYSTPNASTQLPSLVHSSLGITSLLKKQPLKHNTIDRDKILVPPNWDSWGKIRVLRDGFDVETISAGWAEDIQKAWPIMPDLEFSDQDEEGLDLSAVTLYEDWVPDASMSGLHIPGPSLDSTSLETNAVDTQSFLAEQAKVLESTKALSEPKPGTAARRKPGALPDESERFGDSEVRDHIGPVQVNMGGIQVDADDMLRRLKDRQAFANGGGDVTPEEQADPGAVPDVENLQAFFSGLMNRKGATGGVTNGSPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP49</accession>
    <name>A0ABR3YP49_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translation initiation factor eIF2B subunit gamma</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eIF2B GDP-GTP exchange factor subunit gamma</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">GCD1</name>
        <name evidence="11" type="ORF">Cpir12675_005664</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-2B gamma/epsilon subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000206">
        <property type="protein sequence ID" value="KAL1889760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04652">
        <property type="entry name" value="LbH_eIF2B_gamma_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051960">
        <property type="entry name" value="eIF2B_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056764">
        <property type="entry name" value="LbH_EIF2B3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45989">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45989:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25084">
        <property type="entry name" value="LbH_EIF2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 11" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EIF2B subunit epsilon/gamma LbH" evidence="10">
        <location>
            <begin position="420"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="313"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="509"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="320"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="332"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="509"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="524"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF25084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1889760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="544" mass="58504" checksum="D9E5C32D73715230" modified="2025-10-08" version="1">MPHAVTGPSPGVQALILCGPGSSFTTFNSSPDENPKALLPIANRPMVWYPVDYCYRMGINDITLICPASAKDAMQAALSTNPVLTSLPHPRPEILAPAGLTQTMGTAEILRLPEVRSLVQSDFMVLPCDLVCELAGEKLLAAWMVQSASLSDIVGYEKLSGDSSIVHSGGLSVFYETRGETPRIKGEETDYIGVTEIPATAAATQKGSLLPDISNLVVSLPTDSYKDLTEEHKGFPIRHSLLKEHPNVRFMSSKRDAHIYILPRWIMDLVQKNETFESIGEDVIGWWAKATWQDGLGTKLGLGEILNPKSNEHTYISHGGSDTASVGQPETSGNHSKSNKGSSGNGSEGPTPLQGSVPFIQAYIHPTDPTGPIIRRVDTAKLLLHVSLQIAKLPSLEEAGAEPVSPFAHARKVAYPEGVQARTTITKHDSLIADSVTVEEKTSIKECVIGANCQISEGAKLVQCLLMDGVKVGKSCKLTRCILGKRSVIGDGSVLTDCEVQENLLVEPRTEQKDDRLMSSEGLEASDGEDDAMEGDREAEDSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQA5</accession>
    <name>A0ABR3YQA5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005363</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000181">
        <property type="protein sequence ID" value="KAL1890500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="204"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="281"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="371"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="647" mass="69140" checksum="50AF48F65FCC6CCD" modified="2025-10-08" version="1">MKPAYALIGAASVASATKYHFRQKLSNWVSGVSHSRHRGGSSAHYPSVPYEAVPPTVPEGAGDPTIEGGPGLSETAGDQSPPPGAIGIPTGLPRSGNSRHGAERYDFIEKWLEENPEPTSVTVSVSTPTALEEPPKKTVTWVDTILGVDTEEDEDISFGGAFRTIMRPAGLGLGSILEVDNETDEVDESNDILTDFEAPGPIDPVSEAVSEPSESENGIPDSKALEENVIPDSKALEENVIPDSKAPEENTALTQSNFTPFPDWTTFDDDEEVGINPALFTSTTGEPTQEPTQEPTQNPDKENIHGSAQGPDRGLIQENTIPEPTQEPTLHPAKENIHGSAHGPDRGLIQENTIPEPTQEPVPEPTHEPTLEPTTTQSPPVSTSSFSHCNSPCGFLTVIKDASPTGIPVHGGSDEAFLDALEDLDILDDVDGEDVDFTDASSELEAEELEENDDLSDSQAMLDFFELIGFLDDDESSSIENDVASLGVISDENSPSETEVSNNADTEAFSLVKEETAKDILDRVAQQSIKTITRVISQTFGDYYEGSPASIALEAAKKKANDALADAIKAPTMDDGVAAFDRAAEDIVKIGKTSSFSKSESELDDSISDPEILKETIEEISIALSAPFIVSSMMHKGLESDIESVVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSK2</accession>
    <name>A0ABR3YSK2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005147</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000165">
        <property type="protein sequence ID" value="KAL1890990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="260" mass="27986" checksum="12228038FC0697A7" modified="2025-10-08" version="1">MLPQTQGARYMYETYLAPYLQENESTIEEFIVNAHEAAQTVGLEYIKKAIEYARVQFLGMPPDEPDAPPPPPARSNAQTYTQMLLSRFTIPNAKSASTPSSSTGTSAGDFYNLLASAVSAVSGTAAGLSSSTQNANSSVLSMTSSGALIPPTLHDAHEKMNFITAQRERLGIVLSALEKEAAQLQRQAVRDGTRTPRSDFNDDSDRSALSKSRSETDFVKIDAESGDESGMRRRVNTGVWAPWGWSSGEGGEPKDSGVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSY2</accession>
    <name>A0ABR3YSY2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004948</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000153">
        <property type="protein sequence ID" value="KAL1891471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045399009" evidence="2">
        <location>
            <begin position="22"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="452"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="725" mass="75886" checksum="6349603FA39DCE7B" modified="2025-10-08" version="1">MLFQRLFSLASVASLLGSAMAKPVVVKSDTWEVPEAVRPLNHIEIRDPMVEARSQYLEKRLSGKLDLTKSLIDKSLFSSTAAGVRISAKCIECQTQGTVNFQLTNEDVIHPVLRIDFTSVKAWIEVGLIVSGGKAFSLNLYSSQTPVGIGVPGLNIGVLLFVDLVIDIDAEIDMTGGFFVELAENSYIEAALLKGQLEQTAFKGVGVQSIPVKVKYFDVLLTASLRVRVQAGVEAKFTGTTAVVGVYANIIEFVLSLEVVDNDCYFEATEHFNVNIGAYAKLELLFFKVGAPTASTTLFRSPTFTQCIEETKPTTINRIMTKSGQVIGGSPTVPGGLIESTSSYPLITSPPGNASDPSALLPGTIGASKTMSPGTGITKDTGLPTGNPYAMPSGVLGAKKPTGGVGSTGLPYYSNRTKAAIAPSAVYTLSTKLSSQPEISIKSYIPALPHTSATSASSPEYGGKGSGTAAAPHLTSDSYSPKATGAYGQRPYSPLAAASGPSYPVYNATLTSNAGTQATGIPYGTAPPIAGDVATITLCAVHAINCPAEFVQHITVTKPYDSSQTSSAATVTEAPTTSRALFKFPTNCTSLEPLETPIVNVYVPPPDAVIPDSQSLNIIDYGYEQIIHNAAGNETTILLENATAMTVAPTVIPVAPNGLSGDSSFNAIPKIKEYEGPNTKTTASASVSAFPPSSSDIVQSSALTLRSSFEGVMASLVAMFAVTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSY6</accession>
    <name>A0ABR3YSY6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Basic helix-loop-helix protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CBF1</name>
        <name evidence="6" type="ORF">Cpir12675_005133</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000164">
        <property type="protein sequence ID" value="KAL1891007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11398">
        <property type="entry name" value="bHLHzip_scCBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047206">
        <property type="entry name" value="bHLHzip_scCBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47787">
        <property type="entry name" value="CENTROMERE-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47787:SF1">
        <property type="entry name" value="CENTROMERE-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="5">
        <location>
            <begin position="264"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="93"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="190"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="334"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="383" mass="41401" checksum="9642B3AB2B8BCC88" modified="2025-10-08" version="1">MADTITENVDFLKGASPSPNSKRKRDFGDSPAEQRKRSVTATTASTTTTPLIGADAPNLSFIESAVEAAAAANSTGITNAATVAALTALQQATRDANESHEQTSLAMNVEHSHSHSPLTHVPSPLTHSHSPLSHNPHTPHTPHQQQHTHTHQHQHPEPSNDPADPANASSTAAAALGTMYPTMHVPTSTEQQFVQGPTSSSDMNVSGPQGSLVGSTVQPGHESAYPDVGVGHADHSLGLVARGHPDMAMQHRKPAVGTAEWHKQRKDNHKEVERRRRETINEGINELAKIVPQCEKNKGSILQKAVQFIQQLKANEASNIEKWTLEKLLTEQAIGELSQSNEKLKAECERLYRELETYKRMCQSAGLEIPSKQQDTGVPTTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT81</accession>
    <name>A0ABR3YT81_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Complexed with cef1p</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CWC15</name>
        <name evidence="6" type="ORF">Cpir12675_005083</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000161">
        <property type="protein sequence ID" value="KAL1891147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006973">
        <property type="entry name" value="Cwf_Cwc_15"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12718">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12718:SF2">
        <property type="entry name" value="SPLICEOSOME-ASSOCIATED PROTEIN CWC15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04889">
        <property type="entry name" value="Cwf_Cwc_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="72"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="137"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="168"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="261" mass="28914" checksum="DF8D4002CBF8C543" modified="2025-10-08" version="1">MTTAHRPTFDPARGKEALRGPGFHQRLLPAYTSLKYRQTGQGGSGGISAPTDTGDVVHDMRAELLAAEAAHFAKKHGSTLASPHDEDGDNDAVRASLKRSSAATNTDGDEDTGGLLADADAKRRRVLQESRAIDADSSGDDGGPGDDSEADDGDDDSSSDESDDSEAELQRELERVRREKAEKKAREERERAAEQEEERVRDIATGNPLLNKPDFNIRRRWNDDVVFKNQARGTEDKGKKEFVNDMLRSDFHRRFMSKYVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU01</accession>
    <name>A0ABR3YU01_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zinc-ribbon 15 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000155">
        <property type="protein sequence ID" value="KAL1891367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28139">
        <property type="entry name" value="UPF0768 PROTEIN YBL029C-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28139:SF1">
        <property type="entry name" value="UPF0768 PROTEIN YBL029C-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="128" mass="14243" checksum="032D40BBD4903F1C" modified="2025-10-08" version="1">MFFFFTFGEHTFRKDVSDYRGIVCQCHNCGNMSGRVVKSNPWFTFCFLPVVPLSIKGYTDISCHICNFAQPLTNRPDVQAIGSGSSPAVPMQPHQGNPTWQNSSQPPPQAYGANYDAHSPNKPPGQYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU52</accession>
    <name>A0ABR3YU52_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">chk1</name>
        <name evidence="10" type="ORF">Cpir12675_004974</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000155">
        <property type="protein sequence ID" value="KAL1891360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895">
        <property type="entry name" value="CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895:SF32">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CHK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="1"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="511" mass="56919" checksum="D4227EAD3BD6AF5F" modified="2025-10-08" version="1">MIHKEYARSRGQISDRQLRQESNLHNYIGAHPNVIEWFASGEDVTWRWIAMEFASGGDLFDKIEADIGVNPDIAQIYFRELISGVSFIHSKGIAHRDLKPENILMSEDGTLKIADFGMATMYMFENQRKKSTSLCGSPPYIAPEILRCRPSSQVVNGRRVPAASYDPEVADIWSCGVILFVLLIGNTPWDEPSSSSWEFQEYKIKGGRSTDPLWERVPADATSLLRGMICVDPKDRFNMNKIRNHPWTTRRNPLLTADGTVADPLHLATQLLANLRIDLSQLPPVSASQAEGMRISSSQPTDLGHGGVGLDLDFDWERPVIRSMGGGAISSTQPLSYHETSGRSGLGGAGGAQSFGRATVFSRTSLADEPLMSQFSQQTELPISLTQAARRFRDIVPAESLARFFSHVPPDHLVAMLTSALHQINIIVPPVRVNPNPDAECTAVIKVRTVDGRRQSLHGQIQLSRLQYDNGTELLDVNFIKIKGDPLEWRRFFKKVAVLCRDGIYVPEQEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVL3</accession>
    <name>A0ABR3YVL3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Complex III assembly protein translocase and chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">BCS1</name>
        <name evidence="14" type="ORF">Cpir12675_004813</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family. BCS1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000145">
        <property type="protein sequence ID" value="KAL1891808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19510">
        <property type="entry name" value="RecA-like_BCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057495">
        <property type="entry name" value="AAA_lid_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014851">
        <property type="entry name" value="BCS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050747">
        <property type="entry name" value="Mitochondrial_chaperone_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23070">
        <property type="entry name" value="BCS1 AAA-TYPE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25426">
        <property type="entry name" value="AAA_lid_BCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08740">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01024">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="BCS1 N-terminal" evidence="13">
        <location>
            <begin position="36"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="246"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1891808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="464" mass="50562" checksum="97192268DFCDA870" modified="2025-10-08" version="1">MASLPPNAPSPGSPSSFLQLDHLLDNPVFAGGAGLAGIGAIAAFGRRGIVSGAHALRRRLLVNVEISRQDPAYPWVLAWLGQPRAETTGFISSRITRIHNLSVATSLERTPTGGAGAAHFYLQPGYGRHIIQAHGAYIAVNRERHSTANMNTGEPHETVLLTTLWSSRGVFESVFAEAHSLAVKASEGKTRVFAARGVDWVPLGEPRRKRPLKSVILDENVAESISSDIRDFLSRQQWYTDRGIPYRRGYLLYGPPGSGKSSFIQALAGELDYDIALVNLGEIGMTNDKLAYLMTKMPPRSLLLLEDADVAFANRMATDSDGYSGTTVTFSGLLNALDGLAAKDERIAFLTTNFIQHLDDALIRPGRVDQMAYIGNATQYQAKTIWERFYGDVDTDGTGKERFLSKLESLDLFSKDTTRQTSMAAIQGLFLLHKDNFEGVIEAADSLVPKKFGSDTTRPSVGSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY37</accession>
    <name>A0ABR3YY37_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ethanolamine-phosphate cytidylyltransferase</fullName>
            <ecNumber evidence="10">2.7.7.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">CTP:phosphoethanolamine cytidylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">MUQ1</name>
        <name evidence="13" type="ORF">Cpir12675_004199</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from ethanolamine: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.14" evidence="10"/>
    <dbReference type="EMBL" id="JAWDJO010000113">
        <property type="protein sequence ID" value="KAL1893266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004306">
        <property type="term" value="F:ethanolamine-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02174">
        <property type="entry name" value="CCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041723">
        <property type="entry name" value="CCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044608">
        <property type="entry name" value="Ect1/PCYT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45780">
        <property type="entry name" value="ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45780:SF2">
        <property type="entry name" value="ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cytidyltransferase-like" evidence="12">
        <location>
            <begin position="23"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1893266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="447" mass="49582" checksum="74CD976CEE195652" modified="2025-10-08" version="1">MASTIDPPPGTPAPEILENRIWIDGCFDFFHHGHAGAIVQARQLGNELFVGVHSDEAIMENKGPTVMTLDERLAAVEACRWVTRSVTHAPYVTDLDWISHFGCKYVVHGDDITSDSSGEDCYRFVKAANRFKVVKRTPSISTTDLVGRMLLCTRTHFIKSLSAMISGEEGAGTPEERAAVGSSMKDRMKLYATDASGSAPGCDVWFWNASDAAKTKAAIEEAGIFERLFEGKGPKPGQRVVYVDGGFDLFSSGHIEFLKRVTEAEEKIARGEGWYSEQAVNERLGKGEDYPPAYVVTGIHDDEVINQWKGVNYPIMNIFERGLCVLQCRYVHAAIFGAPFSPSKSYLAALPWGIPDAVYHGPTSFMPLTYDPYQGPKTMGIFKEIPTHSYKDVNAGTIVQRITRSREMYEARQRAKGMKAQTEEAHRAREILEEEQLAREAARAVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYG2</accession>
    <name>A0ABR3YYG2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">acetyl-CoA C-acetyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ERG10A</name>
        <name evidence="15" type="ORF">Cpir12675_004315</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.9" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000119">
        <property type="protein sequence ID" value="KAL1892947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003985">
        <property type="term" value="F:acetyl-CoA C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919:SF156">
        <property type="entry name" value="ACETYL-COA ACETYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919">
        <property type="entry name" value="ACETYL-COA C-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12 15" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0630">Potassium</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="13">
        <location>
            <begin position="31"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="14">
        <location>
            <begin position="300"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1892947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="423" mass="44402" checksum="B94BBDF3619044B5" modified="2025-10-08" version="1">MLFTIRQCSSRLGRRSFSSYVSLRRQQIQDVYILSAARTPTAKFNGSFKTVSAPELGAAAIKSALGKSKVPVSKITDVYMGNVLQAAVGQSPARQASIFAGLPPTVEAITINKVCASGLKAVVFAAQNIQLGLADAQVAGGMENMSRVPYYQARSSLQPAFGNITLEDGLIKDGLWDVYNQFHMGVCAEKTAAKHGITREMQDEYALQSYARAQAAWKAGAFAEEIAPVVVKGRKGDVVISEDEGFADVRPEKVPTLKPAFVRDGTGTVTAANSSTFNDGASALVLGSAEVAREYGQGSRVLARIVSHADAAVDPVDFPVAPAKAVPIALKRAGITVDQVAVWEFNEAFAAVIKANEKILGLQGANVNPLGGAISLGHALGSSGSRILTTLLHQLRPTEYGVAAICNGGGAATAVVVQRVETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYM0</accession>
    <name>A0ABR3YYM0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nitronate monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_004114</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000109">
        <property type="protein sequence ID" value="KAL1893461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332:SF36">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G07940)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="351" mass="36834" checksum="3773DB83FD8307C8" modified="2025-10-08" version="1">MTLHSLLSTPLTEALGIKHPIVQGAMALTSGPRLAAAVSSAGGLGIIASFESSPSELRGQISELKAHLTSPDLPWGINLPIIKIGNGARKTNQDYTGGRLAELLDVVAESGAKLFVAAAGLPSHETIERLHNKGMLIAIMAGHPKHARKGLERGVDIIAAQGAEAGGHTGDIGTAVLLPSIIDVAQEFHPPLLHGKPAIVVAAGGIVDGRGLASALVQGAAGAWMGTRFIASEEAVTSALHKQAVVQCGVDGTHMTHVVTGRPLRMRPNWYVKSWHVDKQEKVRELCSRGIIPMKLDEREGRETEIPFLMGQGAGLISDIKPAKAIVESLVTDAAVLLKRGAEIINIKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ32</accession>
    <name>A0ABR3YZ32_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcription initiation factor TFIID subunit 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">TAF12</name>
        <name evidence="9" type="ORF">Cpir12675_004064</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000107">
        <property type="protein sequence ID" value="KAL1893633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07981">
        <property type="entry name" value="HFD_TAF12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037794">
        <property type="entry name" value="TAF12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003228">
        <property type="entry name" value="TFIID_TAF12_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12264">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12264:SF21">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03847">
        <property type="entry name" value="TFIID_20kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription initiation factor TFIID subunit 12" evidence="8">
        <location>
            <begin position="670"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="326"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="505"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="582"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="621"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="79"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="425"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="327"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="367"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="399"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="505"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="585"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="783" mass="84788" checksum="BE98FBAAC8D805E7" modified="2025-10-08" version="1">MNNSTPGTPVMQTQATVNGRQFTIFRPEHIPQMTWLPENERQRYQMGLRSLYASFENSPKDSDEQQGAKKKILEFSMSLNNKRRQILQQQRLQQQQQQQQVVTQQGQTPQQQTPAQVIGQVQQAQVQAQQAQAQAQAQAQSQAQAQAQAQVQAQAQSQTQAQQATQNSHPIAPAVSVAQASAANMANRSPSIAATAPVTTKIPENIMKHISSMPWTPPPTLLDTKGVEAVQKWIGDAKKSYVKALMTIETTRTRLNMLGTAYKEKSDKGTATAEETSRYQHQREQIQKSFADANRYVEQFRRQQEAWRTSATSKVAAAIAGTNRLVQGTQGTTPSGTPVIAPAAAPSQQGTPQPGGTPVHLGSQTEAAKVQQQASATATTANRTQKPQQIQPQPAKPSTPVSTRPSNIPANQIHSHPIQPQMTHQAQQQQQLQAQQQQQQQAQVQAQAQAQAQAQAQAHAQAHAQAQAQAQAQAQAQVQQAQAQVQAQAQQAQIQHQAQFQHQARLHLQQQQQQQLQPQQQLQNTKAHPPSVNTAIATSAIGGQILTGAPSAITPRVGTPQSATSGGQVRPLSMSAAVNMANQNQRQQSVTPTPSTQTTNTANKMAIPKQLPERATQIPQPVAMAGGAGPGRPTYNAGTGTPGGVLAQPAIPKVQIPQYINEAEGDHVLSKKRLDELVRQVCGGQPEGQEGNILAPDVEESIMTLADSFIDNVLLTACRNAKERGSKCLETRDIQLVLERVYNIRIPGYSSDELRIVRKIQPSASWITKLSAVQAAKVTGKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZG7</accession>
    <name>A0ABR3YZG7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004259</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000116">
        <property type="protein sequence ID" value="KAL1893113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="470"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="728"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="828"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="472"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="495"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="739"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="863"/>
            <end position="876"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="902" mass="98856" checksum="DC1CE773A278C657" modified="2025-10-08" version="1">MGRDSDQQLKTLRLKLKIPSDQQDLLQKLSWNDEGSDRNTGNSLNDVHLPPSVLENLLNAHRRNKEFKSKRLAATKTHEHVITQEQLSTSAFQPQIITNDQDQSPQPPPPPSPLSSSGDLTSWASSHYDNIDKGDSSPCSEGSIGNEPASQDANDYVNHDLRNTSPELGETLANPQKLAADALQSSSIPELSVAVPQPLYSRKAIEPRIAITQERSPESNPASPNESTRKEKKSGQTPLRYQNSPTPSSKPLQVSLRQSSARQLQSDAQSQLGAQKAPVTGATTMVPAHSLRQSVAIDAPPCAQRLISLSPHSLAEAEVEKPKRKSRPGRMNMPAFTQTQSCSEVPLLPVEPSIRSTTPSQISSPVLRSQNPPFHSQTCITETPLVALKQTNLPVLADLQSSPPVSLRTKAVHTPSIATPRIGFSRAAPSLAPNPELVVPCSAVTRSIDRQSIETHSHISHLDTFVIEKTQRQPSAHSSISLSNTRKRKAYVRSPYEEPPKERTIDRPFSQASLLTNSHPYATRTSQAVSCCSLNSASAPVPEPDSRLADMIASRRSPIQDFTLQLGMSPYDWFCSIYPDFAATHSSFANGIRYLVYLRTGKRLPECLYDDMLRAFTMEFPLYVSCTKKPMPAISWYMDRLDTPTYQSRAITHSNIDDIYLMVFGFPSDSTSSRHVSGEAKEPASVIPHAKRRRVEVTSPSDYFIPPTMPAKRPLSTERAQIIPPSHPVINQHLAPKPTTGTRATSGQYSDPFPPGEQPSGQFPAHLPDGVGTTHASADALVDDPVKTMQTVFPQHQEPPIPLPSTPPHPMITRSRCSSPHHALVRRVSSHGAGKSKDACSSLPPAKTAAMDFQQRPGRSRRVSSAAQKKLTSSLGAQKRTKTHRKSVAMDWSMIDESSFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZV2</accession>
    <name>A0ABR3YZV2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidyl-prolyl cis-trans isomerase pin4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PIN4_2</name>
        <name evidence="6" type="ORF">Cpir12675_003880</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000099">
        <property type="protein sequence ID" value="KAL1893904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12253">
        <property type="entry name" value="RRM_PIN4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="entry name" value="R3H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034186">
        <property type="entry name" value="PIN4-like_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001374">
        <property type="entry name" value="R3H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF17">
        <property type="entry name" value="RNA-BINDING PROTEIN PIN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01424">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="R3H domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51061">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="220"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="R3H" evidence="5">
        <location>
            <begin position="382"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="74"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="165"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="303"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="562"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="621"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="79"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="113"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="165"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="178"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="303"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="329"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="345"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="565"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="640"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="659"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="684"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1893904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="703" mass="75482" checksum="80D68BEEB163C9A5" modified="2025-10-08" version="1">MSTQPPPPHDIYVEYHQQLPPPSRSPNNSRPSPSQYNAPGFASTMTLPRHAQRGYETLGSSALYTDHLSNGYRSMDHLSNSNPPSANPASNTGSTTTTGGVSPANSMAYGYENPSSNNNHNHNPGAWAYSAGNVATINGSLNGASRQRPMARRAALPTGWADNSSLAMHSHSPQSAFAPHSLGSSHSHSHLPAGLLIDQAMSAADMRGPPAADSDQLIPTAIVIKNIPFAVRKEQLAQIMVDMNLPQPYAFNYHFDNGVFRGLAFANFQNPEDTRAVIERMNGLDVSGRKLRVEYKKMLPEAERERIEREKRERRGQLEEQHRAPMLHQQPSLQSLTAASTVSRGGNNNGNNNHNHNGGNAMNTASNPSSSSSTIPNVDLNDPNTLGFYTELTLFKRDDSREILVFPPTISPEDRRQIHIIAHHMGLEHRSVGETDVRQLHIYKKRHEPSPTGLATINSASLDAHRRGLSRAATFDFATDQPRVITNYSSHAMHRPGPTIEYPMSAEPTAPGLPNNLRAAKSFADLRSMSPSPSANSTSGGYLNTSGLNAFATTNAGLSRLNEFSSGNGSPSLSPSPTLHLNPGASGVADPTMGLSSSMAGLGLGYDPAIAAQVQAQAQSQSRAAAPGAIGSQRPGARPGSDHSISRNVPDRQPRNPEWSEQQQTGFSSRSARAANGNGHMARGSDSSDNTRSTTTTTGSRFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0G1</accession>
    <name>A0ABR3Z0G1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nitrate reductase [NADPH]</fullName>
            <ecNumber evidence="2">1.7.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_003979</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>nitrite + NADP(+) + H2O = nitrate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19061"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16301"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.7.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.7.1.3" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000104">
        <property type="protein sequence ID" value="KAL1893681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="entry name" value="Oxidoreductase, molybdopterin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005066">
        <property type="entry name" value="MoCF_OxRdtse_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008335">
        <property type="entry name" value="Mopterin_OxRdtase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19372:SF7">
        <property type="entry name" value="SULFITE OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19372">
        <property type="entry name" value="SULFITE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03404">
        <property type="entry name" value="Mo-co_dimer"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00407">
        <property type="entry name" value="EUMOPTERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="Oxidoreductase molybdopterin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045674333" description="Nitrate reductase [NADPH]" evidence="8">
        <location>
            <begin position="30"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="9">
        <location>
            <begin position="53"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1893681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="573" mass="62861" checksum="72429EEAD2C22EF4" modified="2025-10-08" version="1">MPLAGGAVRTLTLLASGGLVAAGVSFTLSEPDEHLSGNKDSEANNDTREPLILPRIHLAEVRKHDGNSGEPWITYKDKIYDITDWIAGHPGGDVILQAAGGSVEPYWNIFTIHKSPHVYDILEQYLIGYVHSGDLVNGKIPEESVEDPFSSDPARHADLRTLTAKPRNAETPEYALSDSFQTPNDLFYVRNHFWVPVIEKPDEHSLTIELPDGESVTYSLVQLKEKFRSHTINATLQCSGNRRNHMTKEAGPTNGLQWTTGGISSATWTGVRLMDVLADAGYPVASVRSGTIDPPEDAKHVHFSALEAYGASIPMSVAIDPRGDVLLAYEMNGEPIPRDHGYPLRALVPGHVAARSVKWLNKIILSDEESFSQWQRKDYKSFGPNLVGKKLDWESAPSIQEMPVTSAITSAVLRDDTDADATSSKKVSVKGWAYSGGGKAITRVDVSLDGGATWDQAKLLDDDRCNNTKENHNGSGRSWAWKRWEYHGSVSLAPAASTEPSTSLTFSKDKDALNKPFLCSPDIVVKATDENYNTQPQTQSSIYNARGNLATAWHRVRACERCKVKLSVDSNDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1K9</accession>
    <name>A0ABR3Z1K9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Guanylate kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003614</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000089">
        <property type="protein sequence ID" value="KAL1894488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021861">
        <property type="entry name" value="THO_THOC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13265:SF0">
        <property type="entry name" value="HPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13265">
        <property type="entry name" value="THO COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11957">
        <property type="entry name" value="efThoc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Guanylate kinase-like" evidence="2">
        <location>
            <begin position="623"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="792"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="819"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="852"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="865"/>
            <end position="875"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="966" mass="106118" checksum="041DDB465786C012" modified="2025-10-08" version="1">MESAAGLKVSSAAVIQGVRDVFTRALVDVENVKTTPTIDPALTSASFGDTISNLEAFFAQDEGDRYSSLADGAERKKLRRYAVVETAVRDIFAELIGNTPIDSPKFVSIWNLLDLLAVLSDEERCEPALLFWVIEELLDTQTISGCRQVFDYLESRRERITAKNFKQKHLVILRTCNELLRRLSRAEDTSFCGRVFIFMFQSFPLGDKSSVNLRGEYHVENVTVYDTNSRKEAGADIEAGLDVDTAATADTMEVDEKSTTDQNAVDFEALYPVFWSLQDTFSQPKRLFTPENLAKFKSALELTLASFQTVRGKTGNEDVRRTTGTGALENGQTQAHAHSGQTNITSNSGASNFNPKYLTNRDLFELEIHDLSFRRHVLVQALIIMDFIISLTAKSKEKLAGLVVNKSVAYMDHIVSEQDAAWASEMKRSIADFLRPDPEGPFYLRMVETVLSRDKNWVRWKIENCPSIERPAITIDMFLEAVESINRLSANKTPKMLTMGSLPLDFLDDIESEDEGKDDACFGMGSTRSNPPSIDAFRGKLGDIDFDLDVEQDVSKKAPLEDRKAAISWQALRLASLSNISAFDSIENTDNIGAIYQDKTDPDAVAEPIATDESTASKLPEDVRLVVIAGPPDTNKEALVTGLVDKHPAVFKRVTRHTTREKQDADVLGHFAYVDKKAFSVMVDGDQFLEFGEDPKSGVEYGTTRRMVTNIIDSGKVPVVAVPYDSAQLIKDMGFSARHILVTIPAVEGSEAVPCDTAGFDIVLVKDELGKMLTKLIMFIYEEECDVDNVDAGTGKDAAPADHDIGMGPNLANPADETPTVKDEEPAREPPNTAPEAAKASTPELNGPTPSDDSDTDDASEPDDTTDKDQDLKWLSKEKEAEKLREEVDMASVGKLIAYSDGSKDADGNTGAGWVTTTNGATLETGQTALGKWMEVADAEAHGAYEAAKRAVSDMGAEKIRICLDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1M6</accession>
    <name>A0ABR3Z1M6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Prenylcysteine lyase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_003837</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prenylcysteine oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000097">
        <property type="protein sequence ID" value="KAL1894102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010795">
        <property type="entry name" value="Prenylcys_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017046">
        <property type="entry name" value="Prenylcysteine_Oxase1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15944">
        <property type="entry name" value="FARNESYLCYSTEINE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15944:SF0">
        <property type="entry name" value="PRENYLCYSTEINE LYASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07156">
        <property type="entry name" value="Prenylcys_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036292">
        <property type="entry name" value="Prenylcysteine_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045634628" description="Prenylcysteine lyase domain-containing protein" evidence="8">
        <location>
            <begin position="24"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="domain" description="Prenylcysteine lyase" evidence="9">
        <location>
            <begin position="151"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1894102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="547" mass="61677" checksum="1EB45A5D1A87138C" modified="2025-10-08" version="1">MRLFDSPTAALAVFSSAILATSSEVAVETPATTSLEAPIRNIAIIGAGAGGASTAYYLRKFADEANIPVNITIFEKTNRVGGRSLTVNAWDKPGYPVELGSSMFVPESGIVSSIVREAKLNFRYLEYSEGSSNAGVWNGEELVYRYNFDEDVPFWDRVARFFRFGFDPAMATSRVSKTGDSIKMMYSEPHFPFQSLDKVVSDVDLLTPRNTVGSEFLRKELIIGRYVPEVVQSSTRVNFGSNLDETSGMDMLLSIMPNQALQVSGGNWKIFDYMVQKSQATVNYEIDVGRVDYEPYIRGERYNPSEKPYYAIQTKEERQMQTKNSHYGVAFDDVVFAAPMQFSQITTRFGMMPPMVREVVPYRRVHVTLLATKLRLSPKFFKLEDTDKAPDVILTTLPNKEMPSSGFGSDGRGEKGFYSIIFLRSDMNPKTGYMEDIWKITSPNKPSHEFLFELFDSPVPESIVGNENEESHISWYYTERVAAYPAGIPRDKFYPHALSQGLWYTSSMETFISTMETNALMGKNIAKLMVDKYEDEEKDTAESREGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1W2</accession>
    <name>A0ABR3Z1W2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Complex 1 LYR protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003610</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I LYR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000088">
        <property type="protein sequence ID" value="KAL1894621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20264">
        <property type="entry name" value="Complex1_LYR_LYRM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045297">
        <property type="entry name" value="Complex1_LYR_LYRM4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051522">
        <property type="entry name" value="ISC_assembly_LYR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13166:SF7">
        <property type="entry name" value="LYR MOTIF-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13166">
        <property type="entry name" value="PROTEIN C6ORF149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="3">
        <location>
            <begin position="13"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="146"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="272"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="316"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="374"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="756"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="400"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="414"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="758"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="804"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="838"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="868"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="887"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="910"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="932"/>
            <end position="948"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="970" mass="105387" checksum="AF1C5AACC68204E3" modified="2025-10-08" version="1">MSVAQVIRGDSAQQARSLYRQLLRTSEQFSSYNFREYAKRRTQAAFRENAAQTDSRQIQELMQKGLQELQVMKTRRAHRAGYADHDDFDGLPVRQWREEWVKVAPSSQQEQQASNDIWNMELLHGMPKDTNLLPSHSQELLRLARSGRLHKRPTPQDDDDGTETGAADSSADKPEDDRKDSAFMTRLWKQLPRNAEDQPLSYLAKRRKGTVTIASKTIIDKPLGPTVTRATVRRTDAAGNPYTQEITLQPGVAVDGEIISTRHVVLVSTAQVQESVATETPPVGRRRAPPPKRKPKGPGRGRKKKVIVEGAAPAGGAVAIPVPSSSNTSQVKSEGGGELVSCTMILLEQHHTNPCKTIKPENRSLSHDLELADNSAMASEDEDDGDDGDDDEGDHDAEESQTPKTQQDTEMSDVPDRPLEAEKTPDSKASVENLASNVKEEVKEEVKDDAIIAVNTHPAIDPSPLRNVITLPHSPTTIQALAVTDDYVLNAPQPNKTEEPQEDVAMGDAEPALKVPTKSPEPGLAVGETQLEARVEPIQGSGEPEVGVDGDIEMMDDSGPAVPTVSEKETESAEVNEPLPELENMEDLPIDSVEVVETLEAAQAVQAPEATEAVQAAQVPEVTEAIKAIQTVEVTEGTEATETVEAAETVEAVEISQAIQTAETVKGFEVAEAAEAAEAPIAEKSPAEAIIEEARETQDATEANHADEMVIDEADEDLKSEEVKPEEVHVADVNATTENEPTLAEEAPVIGVGLDVKPQAEVEAKAEANDPEPMAAEPTPQSPSTEQLPVAEDKVTKAPEPNSVEDKNETRMVEEKQVDETKSEARNETKSDAKEEVKEEEMVEDTTEEVKKDTNEETTEGALPGMETTKNTTAESEMQVEQATQEEITKEEKPEEKTEEKPEGETEERPEEKTEGKPEEKPGEVLKPASNPGSATPETATATGAETSMVDESQAKAQVTTAMTVEAEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2B1</accession>
    <name>A0ABR3Z2B1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dynactin subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_003704</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000092">
        <property type="protein sequence ID" value="KAL1894322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028133">
        <property type="entry name" value="Dynamitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15346">
        <property type="entry name" value="DYNACTIN SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04912">
        <property type="entry name" value="Dynamitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="120"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="284"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="28"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1894322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="430" mass="47966" checksum="063217B749888466" modified="2025-10-08" version="1">MALSNRKYAALPDLDSAPDIYETPGLTDDNSTIPGSTLRTQSELDFDEELDDNEGGISRSRLRINEARSRFNPANIDASTVDFSDRVDTKRKSYKTSSRRRRILSDNTEEYGDFSDEEDDESLERNIARLTREVEEAKEQYGKRQLEQQANSEQLLEGKQVALESLGKILEDISRPYGNQVTPHIPKHLTTAPAEQSEETEALETTKQDATYTITYNPAYEQTHALAKVAEFDARLSALEKSLGSNSTLGLELDSNGMPRAILPTLDILQKQVSTLSQASTATLDSISRRVRILTQEADQLTKSRKEAKEAQEALDSAKEGDGSCDQESKINALYGTLPTIENLAPLLPSILDRLRSLRTIHSDAASASDILSCVEKQQIEMALELKEWREGLTKIETAIQEGSTTMQGNTKVMEEWVKDLEARVVKFES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2F8</accession>
    <name>A0ABR3Z2F8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_003647</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000090">
        <property type="protein sequence ID" value="KAL1894470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF39">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="361"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="391"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="436"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="461"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="6">
        <location>
            <begin position="33"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1894470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="538" mass="58992" checksum="4F52A38ADBFB0FEA" modified="2025-10-08" version="1">MRNIEEKQGPDAKPASFPATDGFGLKRDLGSRHINMIALAGMIGTGLFLGSGQSLAIAGPAGALLAYIVMGFVAAGISFTTGEMTSFYPHTGGFIRHATKYVEPALGAATGWNFWYTIAIAVPAELSAAATLVQFWNTSINPGVWLTIFIVFIVTLNLCGVRLYGESEVLFASLKILLILGLIIGGIVINLGGAPNQERLGFRYWRDPGPFNSYIKGGTAGRFLAWWKVMLSAAYSYGNIQIVAISGSEAQNPRYNIANATKKTFWRIALFYVTTVFVVTLIVPYNDSELKISTGNAAQSPFVIAFKRSGVSAVPSIINAIVCTSAISSSSACIYIASRTLYGLSLDGHAPQIFLRCNSQGVPYVAVGFTCLLLPLVYLNVNNNTSTVFSWFVNVTTLAGMIGWIVIEITYLRFLQALRTQGYARDDIFYKGPLQPYLTWFSLIMISLIVFFSGWDVFAKGNFTAAGFISCYLNILIFIILYVFFKIFLKSEVVPLTEVDLAIDVKLVRDEKEAAKIYRKASTGITHKIWKLLRENIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z354</accession>
    <name>A0ABR3Z354_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">VPS15</name>
        <name evidence="12" type="ORF">Cpir12675_003596</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000088">
        <property type="protein sequence ID" value="KAL1894607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd13980">
        <property type="entry name" value="STKc_Vps15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055231">
        <property type="entry name" value="2AA_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045162">
        <property type="entry name" value="Vps15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17583">
        <property type="entry name" value="PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17583:SF0">
        <property type="entry name" value="PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22956">
        <property type="entry name" value="VPS15-like_hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 9" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="25"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="1138"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="1475"/>
            <end position="1490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="952"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1399"/>
            <end position="1426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1525"/>
            <end position="1560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="960"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="1403"/>
            <end position="1415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1526"/>
            <end position="1543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1547"/>
            <end position="1560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1894607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1605" mass="177870" checksum="8D79319D82508153" modified="2025-10-08" version="1">MGQAFSLATPTAGSAGIDVPEMIDFSYEKSMGNAQFMKSIRARHKEGVVLVKALVKPYTPMPLDKYSGEIIRQRKALADIPNVLAFQRVIETETNGYLVRPFLHSSLYDRMSTRPFLEDIEKKWIAFQLLCALRDCHARDIYHGDIKAQNVLVTSWNWVYLTDFSSPYKPTMLPDDNPADFSYFFDTSGKRTCYVAPERFLPAGAPQQDDTKLTWAMDVFSAGCLIAQLFLETELFTLSQLYKYRRGEYDPAITALSVIADEEVRDMIAHMIQLDPERRYTADQYLEFFRGKVFPEYFYSFLHEYMHMMTDISPSAVSPNQTTANAATQKHLGEPDERIDHVFNDLDKIMYFLNTSAPHSSDRGLDVSPQRRSPRLGLDQFPVHLNVANHDHVVSMDIRNFYDDGTLIFLDLVTSSMRNTTRSASRIRACDILLAFAERLTDEARLDRVLPYLVSLLTDDSGMVVIASLRSITQLVQMVKTITPINSHVFVEYLIPRIHTALKGVPNKRPPASRIVRATYASCIGALAITASRFLEMAATLQAKRTSGNGGFSGTDPEVESGNEDEEAAFDELFDNAQRQLYGLFEVHTKILIEDPDVYVRRAFLTSVPALCLFFGPVESNDILLTHLNTYLNDRDWMLKCAFFDTVVGISTLVGVTALEQFILPLLMQALADPEEFVIQSAIHALAQLASLGLLSRPKIWELIDTISRCTMHPNLWIRQTSAEFIAAACKYLSFADVRCILAPMLQPYMKVYTAPRLTEIDILDLLKKPLSRQVYDHAVLWASNAEGSRFWKPFQRLRSFSFNALGAQAKSANTPKALAKVPRDDEDNQWVSKLKNLGMAAEDEFKLLALREFIWRFARTKARVSASASAAATGLSSTVSGPLAGISKNSSLILLGSLGIIPQTVFFDEAPKEEEDSSTTNLMTNGSTPMSKTTYTISDALMDASMTIDEVAKRKKSGSEPSRSASHTRMVSRDESAGPFTRSLRPHTRDNSDAASLISNRRSLKVKPSALTLLDRRDGNKTAAETGTSDTTVFGEVEGPFVPLLSNSKSGDSVALGSTPRAQASSATDAAIKVQHSYEGNDLNILKMLDTLFLQNYPYDMTDFGPFVPPIGQRRGILVAGAPGTRWRPGSRLVAMFSEHTAAINRVAVSPDHRFFVTASDDGTAKVWDTQRLERNISQRSRQTYHHAPGARIVSLCFVDGSSCFVTCASDGSVHVVRVDVTLAKADVTSVTNTAAANSSASVRYGRPRQLRRYQLPSGEFAVWCDHFKQENSSVLVLATNRSRIVALDLRLMKELYVLENPVHHGMPTCFCIDRKRNWIVVGTSHGVIDLWDLRFRMRLKAWGVPGKSPIYRIGHHPTKGHGKWICVAGGAGLGEVTVWDVEKTLCREIYRIASTAPSLGSGSGSSSTGGGTGSTKEGPKAYTAWDVDQDRPEGMLGRFATSIEPPAPTDRGVRAMLVGTGVSQDGLDVKHAFLITGGSDKKLRFWDLALLDNSLVYAGLGPDEPPPRFVASSPAPGVLINTERVPRESRGGRGDRDETQHGRYRAATAATSANRPARNTVISQEQQHLLRSHLDCITDVALLEHPYTMSVSVDRSGVIYVFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4B9</accession>
    <name>A0ABR3Z4B9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Subunit of heteropentameric Replication factor C (RF-C)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RFC3</name>
        <name evidence="8" type="ORF">Cpir12675_003343</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the activator 1 small subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000077">
        <property type="protein sequence ID" value="KAL1895160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050238">
        <property type="entry name" value="DNA_Rep/Repair_Clamp_Loader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013748">
        <property type="entry name" value="Rep_factorC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001679">
        <property type="entry name" value="PRK00440.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669">
        <property type="entry name" value="REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669:SF9">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21960">
        <property type="entry name" value="RCF1-5-like_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08542">
        <property type="entry name" value="Rep_fac_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="7">
        <location>
            <begin position="69"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="389" mass="42205" checksum="BBA752A5CE1EF496" modified="2025-10-08" version="1">MSDDEMDIDVPAVSFHADAPKGKRSAANLPVEAQDSLPWVEKFRPASLSDVSGHHDILATINKFVETNRLPHLLLYGPPGTGKTSTILALARRIYGSDNIRQMVLELNASDDRGIDVVREQIKTFASTKQIFNMGGTSNNSGGASRGMAGYKLIILDEADAMTNTAQMALRRIMEKYTTNTRFCIIANYAHKLSPALLSRCTRFRFSPLKEADIKLLVDKVVEEEGVKIRPEAVEALVKLSKGDMRRALNVLQACHASSAPFQLRGGPKIAERDIERELITTDTIYTCIAAPPPNAIREIFDTLLGTADVTACLTTINAIKTTQGLALADIVTALADELTKLEVAPEAMITWLDGLADVEYRIAGGANETIQTGALVGVIRSGVELSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4S8</accession>
    <name>A0ABR3Z4S8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2828 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003282</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000075">
        <property type="protein sequence ID" value="KAL1895325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058580">
        <property type="entry name" value="DUF2828"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11443">
        <property type="entry name" value="DUF2828"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2828" evidence="1">
        <location>
            <begin position="82"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="168" mass="19132" checksum="77FB59DB07A5C36C" modified="2025-10-08" version="1">MSNHWVLKSKFPVSFPYDGLVGASYERFVEALNNNTGLDEPYADIEDELSNDVTTTKGIHAQRENDHDSSAEYSLMKEIKIHRGTCIQEMTTCLEKAWAKKPLHTLKFILHIRYIHIGKADRKSFNFAAGWLYGTYPRTLACPTIGYEDTEGEFACEYGLQGGPARYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4Y6</accession>
    <name>A0ABR3Z4Y6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal 40S subunit protein S14B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS14B</name>
        <name evidence="6" type="ORF">Cpir12675_003279</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000075">
        <property type="protein sequence ID" value="KAL1895322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="entry name" value="Ribosomal protein S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01310">
        <property type="entry name" value="Ribosomal_uS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_uS11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018102">
        <property type="entry name" value="Ribosomal_uS11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_uS11_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007176">
        <property type="entry name" value="PRK09607.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11759">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00411">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002131">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00054">
        <property type="entry name" value="RIBOSOMAL_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="141"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1895322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="150" mass="15876" checksum="90AFB7BC26DE59DD" modified="2025-10-08" version="1">MAPKKVSSAPKENISLGPNARDGELVFGVARIFASFNDTFVHVTDLSGRETICRVTGGMKVKADRDESSPYAAMLAAQDVAVRCKEVGISALHIKIRATGGNGTKTPGPGAQSALRALARSGMKIGRIEDVTPTPSDSTRRKGGRRGRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6A6</accession>
    <name>A0ABR3Z6A6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PLD phosphodiesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003138</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000069">
        <property type="protein sequence ID" value="KAL1895747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09122">
        <property type="entry name" value="PLDc_Tdp1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010347">
        <property type="entry name" value="Tdp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415:SF4">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06087">
        <property type="entry name" value="Tyr-DNA_phospho"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="2">
        <location>
            <begin position="479"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="585" mass="65127" checksum="75B8BCC363CDC453" modified="2025-10-08" version="1">MAVSKVSHSSAPPTVNSSSHDATPLINTESNGISDETGRMRPPEPILSQFGSMMLNRRKMEEERQDRARLRSASQTTSLKRNRDEASLCTSIKEEPASQKIKLEPNPRSKIPTGPVDTRSFIDVSSDEEELAPCSSIPRKEAITIILDSDSEPDVIPKKEPENKETAAIIATVKPEPKIEEPSPTTPRVLPFPRGSVKKTWLRGSLLNDDAISIQEVMQKDDLIMAVVSSFQWDEDFLRQNIDVFHTKLYLVVFADSDEQKQSYEESKPSANIRYIYPAIYRRGVMHSKLMILKFALYLRIVVPTANFVSYDWGYTGAMENHVFLIDLPLRETSSEEVSPGPFQQSLSRFLELSGFPSALVASLDKYDFTEANRYRFVYSAAGSHRGADRDLTGLCGLANAVKSLGLATSNTVELDVVSSSVGKLTMEFLAKIYTSCRETVLGSLRGRGGAGTICLNSKWFNEASFPRQIFRECISVRPRSLMHSKILFVRNKTESGTKAWAYVGSGNLSQSAWGRLNMPKTAEPSMSCDNWECGVVVPIDEEAGQGYGDDTAPLSIFNRQVPVPFKVEKAVAYEGSQLKPWCMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6I7</accession>
    <name>A0ABR3Z6I7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF3638 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000079">
        <property type="protein sequence ID" value="KAL1895129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022099">
        <property type="entry name" value="DUF3638"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12340">
        <property type="entry name" value="DUF3638"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3638" evidence="1">
        <location>
            <begin position="79"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="414" mass="46221" checksum="A2F588C7C1804570" modified="2025-10-08" version="1">MILQCIHQMGPKDEFGNKRVSVIIVDDDLASKIVTSLEIALCRFEENWDSSVELMTLKFIATQDWVALESELGNIGHLNLSLEEYLSSLLLEIDLGLKIREVQQNNASLMIKPPSDQYSVTQLNMRECKSSVIVTIVSAALENKQRLICVVVAKPQSKQMPETLLIKLGGLVNHRAFQMPYSRGLITTEAQAQLLLRLLQDCQILGDEVLSLVTANIGTVQEKFPQSVEISQHRAGCFPRIRILKVNAIQFLAKKVAKTIYNNGITSFSIIITQPASRRRLAETYLLNIDISASDGVKVEKAFINGKDTGEPFSGLLLLRGLFSMGVLAFGLMKKPWRVDYGLDASRTPKNMFCYTLPCKGHSLSKSRVQSSQCQDGFNLSELLPCRPKRLRAIPVLRRAEAGQRAKDRLCTLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6J4</accession>
    <name>A0ABR3Z6J4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002844</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000060">
        <property type="protein sequence ID" value="KAL1896251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="458"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="621"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="660"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="141"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="458"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="469"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="509"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="522"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="621"/>
            <end position="640"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1018" mass="107862" checksum="9C19765B48A7B077" modified="2025-10-08" version="1">MPTSANTFQTNVHRQKTRKWVEAKAANYDGDDWGDDDDDDGTDDYRPPSMSVPRQATMPPLPRLQQHQQLYQQQQQQKQDTAAAAAAVAVSSTLHSASATSSKRPELPPASNMLLSAKTYTTSLGSSRMPVVPAVTPGSWQGQAQEQSQMPQPQTHMQAQTNTQALAQSQPQTYSQAHNPASESQSSVSSATPSSALPPNNHFGALPSQQHFHRSSTSHIPTSTSVPTGETRQSSWRPSVAGSRSTSPYKNAAINSNAAVHNPVRPSNDRRSTSPYNKTTSSAPAVLKTSKSGPLGTSTLSAMALPPRSVSIGSPLKAQTSSTLPHNSSKETSASQEKQKPEPLPLHLAAPIPSKPLSSVTLRGDNVSPLVKMEAHTKEGQSQQRGSSTSPRLPDVARMSLFTVNFGDTYGKDLESAPPIPALPPLTLYKNEKQHEKPPPSIDQTRVGNNSDVYAISSRSLGNCQPGDTSSSLSESPAPTSAALAPPQSQLATNSSPATSSIHTSSSTKESDRLREEILQSLGPSNEITSTPPINDQVPTRRSTHDSKYLSNIYGDYWPTGDGDETATVAATSSVIVPIGLGINNNGASESVAIAPLSGRKSQHLDMALGMDEKISVAHEMGHAQNEEKRRDFDSSKEVVVDGQSLGTPQRFSWEALSIATDGPSDSHHQTSQTEGSSLPARDLLTQSSTAPAPAPSEHFHIEPDTHSATTDLLVPPPVVSRPSFDSLPEAVAAHDQVSSVGEGVSANLHQANSAGTKVEISVVADTFQDTMFQSEPETRLSPVLESSPPIFAPATETVTTPPSQTNSTTFDSLPTTAAAALDSPPPRVIEPMALRDMLRMSAVSDRMESMNNARKYYLESKTGLSTWVSTMQTDYPEYKLETSIFSKSILPYIPASRSPGSQANLLATSPPRTSSGAATGFSCSHTDFTIPLSQTASASYTATATGGVSNVPAQPNRPTLGGGGLASTFHLPTTTSDLKHSGAKGKEFLLAAGKAGKGLLSKGKSKFRGTGEKVFPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6L9</accession>
    <name>A0ABR3Z6L9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sulfate adenylyltransferase</fullName>
            <ecNumber evidence="7">2.7.7.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">ATP-sulfurylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Sulfate adenylate transferase</fullName>
            <shortName evidence="7">SAT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">MET3</name>
        <name evidence="11" type="ORF">Cpir12675_002868</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>sulfate + ATP + H(+) = adenosine 5'-phosphosulfate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:18133"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="EC" id="2.7.7.4"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="7">Allosterically inhibited by 3'-phosphoadenosine 5'-phosphosulfate (PAPS).</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homohexamer. Dimer of trimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The adenylyl-sulfate kinase (APS kinase) is non-functional. It is involved in allosteric regulation by PAPS. PAPS binding induces a large rotational rearrangement of domains lowering the substrate affinity of the enzyme.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">In the C-terminal section; belongs to the APS kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">In the N-terminal section; belongs to the sulfate adenylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.4" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000060">
        <property type="protein sequence ID" value="KAL1896275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004781">
        <property type="term" value="F:sulfate adenylyltransferase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02027">
        <property type="entry name" value="APSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00517">
        <property type="entry name" value="ATPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.400.10">
        <property type="entry name" value="Sulfate adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03106">
        <property type="entry name" value="Sulf_adenylyltr_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002891">
        <property type="entry name" value="APS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059117">
        <property type="entry name" value="APS_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025980">
        <property type="entry name" value="ATP-Sase_PUA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027535">
        <property type="entry name" value="Sulf_adenylyltr_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050512">
        <property type="entry name" value="Sulf_AdTrans/APS_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024951">
        <property type="entry name" value="Sulfurylase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002650">
        <property type="entry name" value="Sulphate_adenylyltransferase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00455">
        <property type="entry name" value="apsK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004040">
        <property type="entry name" value="PRK05537.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00339">
        <property type="entry name" value="sopT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42700">
        <property type="entry name" value="SULFATE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42700:SF1">
        <property type="entry name" value="SULFATE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01583">
        <property type="entry name" value="APS_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01747">
        <property type="entry name" value="ATP-sulfurylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14306">
        <property type="entry name" value="PUA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP-sulfurylase PUA-like" evidence="10">
        <location>
            <begin position="5"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Sulphate adenylyltransferase catalytic" evidence="9">
        <location>
            <begin position="176"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="APS kinase" evidence="8">
        <location>
            <begin position="397"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal" evidence="7">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Allosteric regulation domain; adenylyl-sulfate kinase-like" evidence="7">
        <location>
            <begin position="397"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="199"/>
            <end position="202"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="293"/>
            <end position="296"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="436"/>
            <end position="439"/>
        </location>
        <ligand>
            <name>3'-phosphoadenylyl sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="518"/>
        </location>
        <ligand>
            <name>3'-phosphoadenylyl sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <feature type="site" description="Induces change in substrate recognition on ATP binding" evidence="7">
        <location>
            <position position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1896275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="576" mass="64075" checksum="B76F2688DF5D0F56" modified="2025-10-08" version="1">MATPAPHGGILKDLFARDAPRHDNLAAEAEVLPALVLSERHLCDLELIMNGGFSPLEGFMTEADFNGVVAENRLASGVLFSMPITLDANKETIESLGIKAGSRIVLRDFRDDANLAILTVDDIYKPDKVNEAIKVFGSDDDTHPGVKHLFDVSQEFYIGGKVEAINRPAHYDFLDLRYTPAELRSHFEKLGWQRVVAFQTRNPMHRAHRELTVRAARSQQANVLIHPVVGLTKPGDIDHFTRVRVYKALLPRYPNGMATLALLPLAMRMGGPREAIWHAIIRKNHGCTHFIVGRDHAGPGKNKNGKDHYGPYDAQEAVKQYTEELGIQMVEFQAMIYLPDSDEYKPVDQIAEGTRTANISGTELRNRLRTGKDIPEWFSYPEVVKVLREENPLPSAKGFTILLSGYQNCGKDSIARALQVTLMQGGGRPVSMLLGDTVRHELSAELGFSREDRDKNISRIAFVASELSKAGAAVIATPIAPFEEAREQARQQVEKNGGLFFLVHVATPLEYCEKTDRRGIYKRARAGEIKGFTGVDDPYEVPQKADLVADCSKQTTRAVVHQIILMLESRGLLDRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z728</accession>
    <name>A0ABR3Z728_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000057">
        <property type="protein sequence ID" value="KAL1896476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045994787" evidence="1">
        <location>
            <begin position="19"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="195" mass="21609" checksum="9F3C72EF29A85569" modified="2025-10-08" version="1">MRLLDFLSLSFLLVGVNAQDTLKDHGYTFNNLGDGLCTITSHHYSKGEQPLNEFKVSKADKTIAVDKILNHLEEKRPDQLSVSAIMTAVCQKYGLSPDGLSKAVIKASKDTCLEDVLSAYRWLHPDVKEDEKVVATITLDKDNTDFIVRHILYDCYAFEIVAGMLTSNSIVGDISIEEGNEDCSISYFINPSVGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7G9</accession>
    <name>A0ABR3Z7G9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1996 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002934</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000063">
        <property type="protein sequence ID" value="KAL1896021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018535">
        <property type="entry name" value="DUF1996"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662:SF12">
        <property type="entry name" value="DUF1996 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09362">
        <property type="entry name" value="DUF1996"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1996" evidence="1">
        <location>
            <begin position="30"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="323" mass="34883" checksum="B516722F3F3E4D3E" modified="2025-10-08" version="1">MRSALLLGAAGLASAYTITTAGLFMHKNMDPIVIPGKYQSHLHSFFGSDSVTPNTKTSAELQAGCSSALNPNDYSSYWFPALVLKNDDGTVTPVTVNRFSAYYVSINNAEIAIPQDFRNVVGNALANKQADVPELAGHSWFCEGEPVDESKDPAAFPTSTCSTHLQTLLLFHDCVNPDTLESDYSGTQHWTSFGVPANRCPAGMKRIPQLRFSIRFDLRKLLPNGWKGAPPLELACGPSYCFHGDFINGWLPEAAENMLKATSKTEFAGVDGPDGKYDAGSICGAKNAQDRSPNEGTSDFLEAANIVASSKAAAKRRATRHRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7J9</accession>
    <name>A0ABR3Z7J9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Secondary metabolism biosynthetic enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_003076</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000067">
        <property type="protein sequence ID" value="KAL1895798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050859">
        <property type="entry name" value="Class-I_PLP-dep_aminotransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42790">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42790:SF1">
        <property type="entry name" value="AROMATIC AMINO ACID AMINOTRANSFERASE, HYPOTHETICAL (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="7">
        <location>
            <begin position="125"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="622" mass="69317" checksum="F65435C3ABB9C83A" modified="2025-10-08" version="1">MDALHTTVDRDAGADLTPPRDLSHLFSEATTNRQPSQIKAYYKYFQIPGIGNIAAGLPHVSLFPFDTLEANIAPPTRWTPSPSVDPNCGPDPANLSPWSGVSTSHITVPKTSACSEITTKIDLASALQYGTSDGYPTLRSFLRQFTRDVLHPNFAYKGGPEIILTCGSTDGFNKALQLLVNSWSQNDPVGKREGILVEKYMYSNVLAQAKPLGVNIASVELDDQGLVAHGPGSLDDVLASWDETKGKRPHILYTVTTGHNPTSGVLSFQRRKEIYTVACKYDVIIVEDDPYWYLQFPNSSVSQAKSRDQPVPSTGLLTAGWTPTHRSGYRFIDSLVPSFLQFDTEGRVIRLDTFSKTIAPGCRLGWITAQPAFIERFMCITEATTQQPSGFVQSMVATLLLGSQPPAVMTAYQRLTRYEQTLFSGWNMDGWVRWLAGLNGAYERRMSLMSRSIDQGTYQLKQSTPVDPVVSDWGVITKTRLLSFNWPQGGMFLWLRIHFENHPLWRSRGTEHSLITGPMLSTALLVFLMDKPFLVLASPGLMFSANDQIREESGWRFFRLCFAAEDEDKIEPTTKRFVDGVQRFWRIKDPAEVKRLVKKFSNSDSETSDLNGAANLGVPMNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z983</accession>
    <name>A0ABR3Z983_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">REM-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_002415</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RICTOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000047">
        <property type="protein sequence ID" value="KAL1897233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.160">
        <property type="entry name" value="HR1 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011072">
        <property type="entry name" value="HR1_rho-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036274">
        <property type="entry name" value="HR1_rpt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028268">
        <property type="entry name" value="Pianissimo_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028267">
        <property type="entry name" value="Pianissimo_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029453">
        <property type="entry name" value="Rictor_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029451">
        <property type="entry name" value="RICTOR_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029452">
        <property type="entry name" value="RICTOR_V"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13298">
        <property type="entry name" value="CYTOSOLIC REGULATOR PIANISSIMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13298:SF11">
        <property type="entry name" value="RAPAMYCIN-INSENSITIVE COMPANION OF MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02185">
        <property type="entry name" value="HR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14663">
        <property type="entry name" value="RasGEF_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14666">
        <property type="entry name" value="RICTOR_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14664">
        <property type="entry name" value="RICTOR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14668">
        <property type="entry name" value="RICTOR_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00742">
        <property type="entry name" value="Hr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01303">
        <property type="entry name" value="RasGEF_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01307">
        <property type="entry name" value="RICTOR_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01308">
        <property type="entry name" value="RICTOR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01310">
        <property type="entry name" value="RICTOR_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46585">
        <property type="entry name" value="HR1 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51860">
        <property type="entry name" value="REM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="REM-1" evidence="4">
        <location>
            <begin position="51"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="92"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1276"/>
            <end position="1313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1340"/>
            <end position="1360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="97"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="129"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1278"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1340"/>
            <end position="1350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1897233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1360" mass="151974" checksum="8A2E6DB53BDEA139" modified="2025-10-08" version="1">MYSGYTQQRNGTSNGGPGSYNSDIRNQMLTGSARAPSRTDNYPRSGVASVAGAPEEEDDATTEQRITALKESLNREMKIREGSENMLEALNTKKAKQTKEQRARVEAELTSSNNRIQDLRRRLHVAQKQRGSPGTPTRSRVEGLLPSSGFRSPRSVSRSRAGAESDVEETTESPSVTLSDLIQALEVDGMSAEYYVSRSNSLVDLFKRHITLKYDLVWHVFGKRIQAMLLSESREVVAAGYRMTRYAIYDIGSLRKVRHLNIDFLIVTSLLKDRKADVEREQALKLVRAFLDIKDGVNQISRAVVRVIASIAENIDERRSGNPAAEATDPEDRLRPMCIETLAEILLRDPQLLAASGGLAPLSDALSEGSYKAPASLTSVFLYLLDTSQGRRFLRPGYGIDVLFSPFTDLLNESEALLRQNAKAITVAMRSWSGLMSLTMYNNRTVKSLLDSMISPFPAVRETIIDLLYTLLRIKSPGWAQSFLAGRRLTTYGRVATLKSQDGAKSTPFFDEDGGEQNFVDHYTALILAVLVKAGLLPKLLNVTQTSDNPTLTRKTTLLIGETLKLASRLLPASWNTEIQLLPELFANAIKFEGAERHTASGIVYQISSVSRTLYRSVGPSSAGGFGGSDFGDMTEYSKSVAAIATDEGTFRQMLIDSNVLNSSNYGKWKWDIILKIVEGPLHIGKRVDEAMKASKFLKRLMSFYRPFKYRFSEIKNTRNTQKYVKVGCALMYALLQSSEGCKVLSESKLLRQLSECLAQCDPTSGATYQFPMFSKTRLTDTLCGGYFPMLGVLSGDSHGLRFMERWRMFTMIYHIIDHNQRPDIIKLLLSNFEYIIPGHPRVILSKALTGGTKKIRIHASNVLRKYAVHPSSYAPASNTLGDSKWAIELLVTQLYDVELEVCATAVKILEKACSRKAYLEYIVYCKPSLDHLGELGAPLLLRFLSTSSGYQYLNGLDYISNEMDDWFLGRNDSYVGLVEASLARAFLDPAEEQQSRPPQFDDTELDGDFTEMHVPPHFYRELTRTSEGCKLLRDKGHFDEFVATIREFGMQSEDPESLTKVKGCLWAVGNVGSMELGAPFLESCDVVELIVHIAQEHEIMSLRGTAFFVLGLISRSIHGLEILTECGWDSAISITGSSYGLCIPKNLGKLLSLRPWAAERLAQIDLPSSQRTMPYPPPVMPPHAPLEDDTPVPTDPEGIENRAVQLVVDLSNTVLFKRAMNSLMQLKQKCPAGFLSITLYKKIHTLMEYSHYRFPIRRMVIDLFPPSVVRSVVLENSNDDESDTPDEDDREIRNQTQSQNHSRRESLAKRHIQARKGSVAALQAEGLEATIVEEELKKERARSVSDPLHELSVMQNDQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9B0</accession>
    <name>A0ABR3Z9B0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Low-affinity Zn(2+) transporter zrt2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ZRT2</name>
        <name evidence="10" type="ORF">Cpir12675_002433</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ZIP transporter (TC 2.A.5) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000047">
        <property type="protein sequence ID" value="KAL1897250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004698">
        <property type="entry name" value="Zn/Fe_permease_fun/pln"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00820">
        <property type="entry name" value="zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF69">
        <property type="entry name" value="ZINC-REGULATED TRANSPORTER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="136"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1897250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="360" mass="39122" checksum="B299910C381B3708" modified="2025-10-08" version="1">MAFEQSLVHRRHEIECSTEVDLNRRGLRIASIFIILAASLLGALLPLFLSRLNTKYSPKKIFFIFKFIGTGVIIATAWMHLLSPAVEALHSECLADKLGEYDWVFFIALMTVLLMVLIETLATHFSDSIARKMGGSTSRAGAHNDTMADEAAPTNSSISDNEIPVEKRDNTPSAPVDLSYLPHSHGHGPHIQSHGPVSNIAFSGQIIAILILEFGVIFHSVFIGLVLSTTDEVVILTIVLVFHQLMEGLGLGSRLAAVNWPEGRGWWPFLLSLLYAVSTPIGIAAGLGARPNNGNTQTLINGIFDSISGGILMYTGLVELLAHEFMFNEDMNRSPLRVKFAALSCVGFGAGVMALLAKWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9P1</accession>
    <name>A0ABR3Z9P1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002886</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000061">
        <property type="protein sequence ID" value="KAL1896239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="418"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="356"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="451" mass="49578" checksum="C20CE97E5B28DCA9" modified="2025-10-08" version="1">MFNTTPSVSAAATEYHHHQESVNSCVSAANTILHSDDSDDDTLPPSLSKSTTLRKGKTPPGTSSATATTPTAALNLNASTKKKRIRKFTSQERLHHRTFEKSRRQSFKFNLGMLASLLPNVAFTETKRLSKHVVTAESSIQHRKANSRCRQALASARALLAERDEILVQLNYFLANAGKPIQQPKIKADDFSLLYEFENDAAAIKNAALAMGRQLNANGEPKMHDDEEDYHLSPSEQAEMANAHDKPGPDAFVRATMEGVIGPDNPLGCSSPIRSVAEAHVQQPYPHPPPQPHPQAQYRYSNYPQTQQHHDTGQDSEMATPLQASTSPGGQFAMPHQQAEPMFLNLFPTQQLPAASPENSPWSSISSPQVGDGFYVASMGSSQQRQHPHNHHQHHQQSESLTQLPSLAVYHTHDHGIPFAQSIHPHSRQQPPSTQGHHSQSTTGSSWNFAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9W2</accession>
    <name>A0ABR3Z9W2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DUF803 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_002645</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000053">
        <property type="protein sequence ID" value="KAL1896922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008521">
        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF86">
        <property type="entry name" value="ADR321CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="332"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="382"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="483"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="333"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="400"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="439"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="451"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="483"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="511"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="536" mass="58086" checksum="EF3A2B7A73A07BE6" modified="2025-10-08" version="1" fragment="single">IGIFVGILSTSIQSIGLTLQRKSHILEDIKSPLARRAPHLRRRWQIGMAMFITANLLGSSVQISTLPLPVLSTLQASGLVFNGLCATLILAEPFTRLSLIGTVLVCLGALLIAVFGAIPAPTHDLPELLNLMRRRPFVAWMTTTLVIVIIVAITTDVFTAWAVRRRHFEHNPRFRLARGLAYGCISGVLSAHLLLVAKSAVELIIKTVIDGDNQFVHWQSWMAVIALVSLAIIQLSYMHRGLKLVSTSVFYPLVFCVYNIIAILDGLIYFEQTDCISTLDASLIALGTAILLGGVLALSWRLSDDCAQAQGVQPRSPNTIGFVEDTEEESLLESESPSLIPSPLASPTSTGIAPGAPQFSTYQTFSPRVESYAEIWDELHDQHSHPTSPITASAPKRRSLSSNADEGTSLLSNSHAKNRRQRRSIAGSGTQYGNSHAYSHSHSHASRRKSSNISSSGVAGSGPTPKPLQDAVGGLFKMRWFSRKDKAKSEANEHSKTRPHDEEAQSNTPWPVLPDAPSSPSPSPPGTYDSGAHPPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA53</accession>
    <name>A0ABR3ZA53_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Autophagy-related protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SKS1</name>
        <name evidence="10" type="ORF">Cpir12675_002545</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Preautophagosomal structure membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000051">
        <property type="protein sequence ID" value="KAL1896966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13993">
        <property type="entry name" value="STKc_Pat1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045269">
        <property type="entry name" value="Atg1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348:SF68">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE ATG1C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0072">Autophagy</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="82"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="534"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="537"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1896966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="592" mass="65150" checksum="C6BE6B5B3EB175E0" modified="2025-10-08" version="1">MHHVQQRINSRFHYAAVDAPSVCGNSMPCFRPCSPVDSGYGSCPPANLMSVPPTGNNLLCTPPLPADRIGMILRVPNHDLKLRLLSIIGTGAYGVVYLAQAIDTDKNYAVKVLNKFTAEGQPLDQRQADFQRREIRLHARVQHHPAIVSMYAIIDNVDCTYVVMEYCSEGDLFHNIAELGRYEGCNEEARGIFLQLVGAVMYCHERGIFHRDLKPENVLVTNNGQEVKLADFGLATSSAYSGDYGCGSTFYMSPECLDVWSEKKYNCAANDTWGLGVILVNLMCGRNPWKQASSEDSRYRLFLKNPDFLQGILPITPEFNHILGRIFARNPNDRATLPEIFDMVEKCPAFTAVSAPANTKASSVAAVLTNYPSPPQSVSSEGNEQKEDEDMCDDEQTTYYEAESHVNAISVSGAEPKLINDHGSQRVLTPETAFQAHSSVLTPQIAATAAAEPFVSIVNAEYHPTYAAGYAATASPADAQFFPAPVAYNHMQPQQFWGSDAIYQHSLQPLPDFQTKMASLQHAAAYACPITPPPEPQQQLHSYPQQPQPQQQPRSGWVFPLFNFQFSASQISGVGVVPHGGISPLNLLTHHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAB1</accession>
    <name>A0ABR3ZAB1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">COP9 signalosome complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">RRI1</name>
        <name evidence="12" type="ORF">Cpir12675_002447</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Component of the COP9 signalosome (CSN) complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M67A family. CSN5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000047">
        <property type="protein sequence ID" value="KAL1897260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08069">
        <property type="entry name" value="MPN_RPN11_CSN5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040961">
        <property type="entry name" value="CSN5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18323">
        <property type="entry name" value="CSN5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0736">Signalosome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="11">
        <location>
            <begin position="51"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="190"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="202"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1897260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="353" mass="38856" checksum="69B40714FD6AED42" modified="2025-10-08" version="1">MDAEFANWQMKNNIKLVDPALDALYNYDPATVRKENDGRPWKNKPQYFKNVRVSAVAMIKMATHAQSGGDIEVMGCMQGYVSGDTFIITDAFPLPVEGTETRVNAQDEANEYLVQYLKACRENGREENLVGWYHSHPGYGCWLSGIDVETQKLQQQFNDPFLAIVVDPHRTLSSGKVDIGAFRTFPDTPTSGASAASGVRAKNTEESRVDVGDASGSDIPSHKVADFGAHANRYYSLNVSHYKSTLDSNLLSLLWSKYWVQTLSSSANQSHGAFATQSMRDLALKMNETSVAIRKSYTNTMPANFTSAADRSMQNTAQASRDLAGMEKAGVTALNIKKNLFNGLGLNKPRTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBL9</accession>
    <name>A0ABR3ZBL9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cysteine and histidine-rich domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_002085</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000037">
        <property type="protein sequence ID" value="KAL1898066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06466">
        <property type="entry name" value="p23_CS_SGT1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1130.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007051">
        <property type="entry name" value="CHORD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039790">
        <property type="entry name" value="CHRD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46983:SF3">
        <property type="entry name" value="CHPADIPLOID STATE MAINTENANCE PROTEIN CHPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46983">
        <property type="entry name" value="CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04968">
        <property type="entry name" value="CHORD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51401">
        <property type="entry name" value="CHORD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CHORD" evidence="6">
        <location>
            <begin position="5"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="CHORD" evidence="6">
        <location>
            <begin position="135"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="CS" evidence="5">
        <location>
            <begin position="216"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="96"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="327" mass="35537" checksum="8D3CD0D9C4AC2774" modified="2025-10-08" version="1">MAQKCVRQGCGKAFADVNEPCVYHPGPPIFHEGQKGWKCCKPRVLTFDEFLTIPPCTTGIHSTTEAAAKLEEAAPVNQDELDLKISKMNSAAAAAANVPGRKPVSAPQAVAATPPPPPESEDDDPSLDIPDGKVCRRRTCGTAFKAGASRDGESCVHHPGVPIFHEGSKGYTCCKRRVMDFEQFMKLEGCTTKNRHLFIGSGLKEKKTSNGAEEILETVRRDFYQTVGTVIASFFLKKIAKEKSTVEFTDKLIKLDLVTSDPTPKRFTKDINTFGIIDPAKSEFKILGTKLEVVLAKGDDSSWPVLSSDDGHSGEILQVGRAGRMQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBS8</accession>
    <name>A0ABR3ZBS8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dephospho-CoA kinase (Dephosphocoenzyme A kinase) (COAE)</fullName>
            <ecNumber evidence="3">2.4.1.145</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">COA5</name>
        <name evidence="3" type="ORF">Cpir12675_002387</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PET191 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.145" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000046">
        <property type="protein sequence ID" value="KAL1897283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008454">
        <property type="term" value="F:alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018793">
        <property type="entry name" value="Cyt_c_oxidase_assmbl_Pet191"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28627">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28627:SF1">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10203">
        <property type="entry name" value="Pet191_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="142" mass="16271" checksum="A5EE41DC539B0212" modified="2025-10-08" version="1">MPNSCRELRDALAQCLQQSDCVMVQRNSAADCLRKPHVDTLPPACLQLKRGFGECRRGLVDMRKRFRGNMPVSYKHMQDADQGVNYQLYAGAPAFATGARVTDGNEPEERDWRDVESERYMKEMEAMRAKKAAEEEQRLSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCD0</accession>
    <name>A0ABR3ZCD0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytoplasmic tRNA 2-thiolation protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">CTU2</name>
        <name evidence="3" type="synonym">NCS2</name>
        <name evidence="5" type="ORF">Cpir12675_001961</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CTU2/NCS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000034">
        <property type="protein sequence ID" value="KAL1898336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03054">
        <property type="entry name" value="CTU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019407">
        <property type="entry name" value="CTU2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20882">
        <property type="entry name" value="CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20882:SF14">
        <property type="entry name" value="CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10288">
        <property type="entry name" value="CTU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1898336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="474" mass="51155" checksum="B4423A6AEAD56AC7" modified="2025-10-08" version="1">MEGSTYDDVGKSSNGCASGSSQQKSSGGGCGDSSSTISLGRTNGCGGNSESTTTASGDRGRSDEDSASAGPKACRRCKKNEGTISMRGQPTCTDCFVPFARLKVIKRLNTLHRDLADMRGSRAPQKTRYLCGLSFSPSSAVLLSMLHDNIEYLEQKGRGGIAYAVTVMHIDTTLNEAGRLAATALLEAYQARFPRLSFEHYALEDALQLRGVNWAALGIELPHKEGEELRQDRARRLCVALDALHSVSARVDILRLMVRHALVSRAMQGGCDAVLLGTNMTGLAELAFSEVAKGRGASVPWLTQDGLFPLPSFGGVVGQEEEIDGAQHGNITGKTSIPVYHLLRDVFRVEVLTFSGLAIPTPLTPLIPSLAENKQQQQMAKKTIVSHKNLSIEEVMARFFNDAETTGQASVVSNVVRTTDRLARLCENMSQMCEICGLPLDGEGDERWRGEIGVQEDEEEKKGLCHGCQRSLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCD9</accession>
    <name>A0ABR3ZCD9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Guanine nucleotide exchange protein for ADP-robosylation factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SEC7</name>
        <name evidence="9" type="ORF">Cpir12675_002150</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000039">
        <property type="protein sequence ID" value="KAL1897807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00171">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032629">
        <property type="entry name" value="DCB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015403">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HDS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032691">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HUS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046455">
        <property type="entry name" value="Sec7/BIG1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF375">
        <property type="entry name" value="LD29171P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20252">
        <property type="entry name" value="BIG2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16213">
        <property type="entry name" value="DCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09324">
        <property type="entry name" value="Sec7-like_HDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12783">
        <property type="entry name" value="Sec7-like_HUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SEC7" evidence="8">
        <location>
            <begin position="647"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="102"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="235"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="280"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="618"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1049"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1546"/>
            <end position="1589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1846"/>
            <end position="1867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="115"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="627"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1059"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1558"/>
            <end position="1571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1897807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1867" mass="209912" checksum="78704345477949B4" modified="2025-10-08" version="1">MSSLKFVVSSLDAIAVSKEAQRNKQLAESVKTALEAIKASDPQFPDAELIFAPLQLASKSPNIQVTTTALDCIGKLISYSFLSVPSSTATPSIIVADADAQPVNIDPENPDKPAEQPPPETDLPSPLPTHSNVSLIERAIDTICDCFQGDQTPPEIQLQILKSLLSAVLNDKIVVHGAGLLKAIRQVYNVFLLSRNTANQQVAQGTLTQMVGTVFERVKTRLNMKEARLSLSNLRQTASHGTLDDSADSANGQQIQDGEEEEEDNEATKLTLKDLEHHKSFDDSHVGDGSTMVSRLKPEPRRGRSVSEVALSDVAEDNEALDAEDEVYIRDAYLVFRSFCKLSTKVLAPDQLFDFRGQAMRSKLVSLHLLHTLLNNNLSVFISPLCTIRNSVGTESTSFLQAIKYYLCLSITRNGASSVDKVFDVCAEIFWLMIKFMREPFKKEIEVFLHEIYLAVLNRRTAPASQKLTVANVLCRFCADPRALVEFYLNYDCGREVENFFQGIIEDLSRFAISQIVITPAQEQLYEEKNGKITPPSEWQLRTILPPQLSAAHMAPKEDVETDVPKEYAIKRVCLEALVESLRSLVNWSEPLRQDLEPTSEGADARLSIEIDTRPSIDPSIHDRNFNNRLETPITPSTPILDDDPDQLEKEKARKTAMTNAIKLFNFKPKKGIKTLISERFIPSDSPLDIARFLLSDDRLDKAMIGEFLGEGDQANIDTMHAFVDSMDFNKKRFVDALRLFLQSFRLPGEAQKIDRFMLKFAERYVTGNPNAFANADTAYVLAYSVIMLNTDQHSSKIAKRMSKEEFIRNNRGINDNADLPDEYLIAIFDEIANNEIVLNSEREAAAAAGIVNSQPSGLAAGLVQGFSNVGRDLAREAHLQQSEEISHRSEQLFRNLFKNERRNAKTGNKFIPAISSKHVGPMFEVTWMSLFSAFSSQLQKAQNIEVNKLCLEGMKMATKIACLFDLSTPREAFMSAIKNATNLNNPHEIMAKNVKALKVILELGQTEGNFLKGSWKDILMCISQLDRLQLITEGVDENAVPDVSKARFLASPRDGSDPRASISSTRRPTISSRTGPVSQGLSMEIAAESRSDEVVKGVDRIFTNTAKLSGDAIVHFARALTEVSWDEIKVSGSNDFPRTYSLQKIVEISYYNMTRVRIEWTHIWDVLGEHFNVVGCHANTAIVFSALDSLRQLSMRFMEIEELAGFKFQKDFLKPFEHVLSNTQNVAVKELVLRCLIQMIQARGDNIKSGWRTMFGVFTVAAREPHESIVSLAFENVTLVYRSKFSVVIFQGAFTDLVVCLTEFSKNMRFQKRSLQALEALKSIIPRLQKTPECPLSRSKKNDQSLPKPGTSAEEGFWFPILFAFHDVLMTGEDLEVRSNALEYFFQALSKYGDNFNPDFWDILWRQQLEPIFMVLRSRPEMTNALNHEEMSVWLSTTMIQALRNLIALFTHFFDSLEYMLDRFLKLLALCICQEHDTISRIGGNCLQQLILKNVAKFTLEHWSLIVSAFCELFERTTARELFSANTLNSATTLTPLANGYDFSGPLTSSESPPSAVDEKSLKINGREDSDAANENTRGEVDESELTSLEEARTPILEDYKPSSNLQQPQPVVTAARRRFFNRIISRCVVQLLMIETVNELFSNDAVYAQIPSTELLRLMALLKSSFLFARKFNNDRDLRMRLWREGFMRQPPNLLKQESGSAATYISILFRMYADNSPERAKNRKDIESALMPLCKDIIKGYILLEEESQHRNIEAWRPVVVEVLEGYAMFPREPFAAFIKDFYPLTLDLLCKKNSTDLRAALVQVLRRVGDVGLGISELGKPLADRCGSTATVWTDIDHVNEQESMDAEEGAMDTMHRGGPAEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCU1</accession>
    <name>A0ABR3ZCU1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000036">
        <property type="protein sequence ID" value="KAL1898097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.150">
        <property type="entry name" value="Haem-degrading domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005624">
        <property type="entry name" value="PduO/GlcC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038084">
        <property type="entry name" value="PduO/GlcC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010371">
        <property type="entry name" value="YBR137W-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28255">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28255:SF1">
        <property type="entry name" value="UPF0303 PROTEIN YBR137W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03928">
        <property type="entry name" value="HbpS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143744">
        <property type="entry name" value="GlcG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="196" mass="21273" checksum="766AD8F3B7E8D924" modified="2025-10-08" version="1">MAPKVWTRRRQAGAALEKVQTAIQSPQAPEPIPKPHSDLAALKADGDSFTFSSFTSDDAFELGTLLYARLLPYAQNGQPTLISIALANSSQVVYQTVTGPGITPDNECWVRRKRNTVLRFGCSSWFMCKKFGGDETAFAAKYAIGDTQKSDYAIHGGAIPIRVHGVDGLVAVVVVSGLQQHEDHGVIVDVIKSNWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCY7</accession>
    <name>A0ABR3ZCY7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Alkaline protease 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_002103</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000038">
        <property type="protein sequence ID" value="KAL1898017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF58">
        <property type="entry name" value="ALKALINE PROTEASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6 7" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045287107" description="Alkaline protease 1" evidence="9">
        <location>
            <begin position="19"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="11">
        <location>
            <begin position="26"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="10">
        <location>
            <begin position="207"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="455"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="455"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="484"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1898017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="500" mass="51947" checksum="DA324AF9B5234D28" modified="2025-10-08" version="1">MVSFKNLALLLAATLTLGEVNPSSQKYIVTLKPNISKRDLDAHISWARGVHANTKASPDLSGVTKTFQLGSFTAYLGSFDGSAIDEIRSSADVDSIEEDSEWQLHAALPIAAPLVVPLESYRHSSAKDSSTMGSLPFKRNDQGSPWRLSDGDGIVVNSTDSEITQDTTGTSTQHEAPWGLAALSNKASGGTDYIFPSNGGINTYAYVVDTGINGDHEDFEGRVELGYSVSGDDGADEIGHGTHVAAIIAGRQSGVAKEARIVSVKAFVGGTSSLSKLIEAYVWAVSDIETKNRTAISVINLSVGGNFSATFNALVNEAYTKGIVNVVSAGNSDDDVSKYSPASSTSAITVGAINPKWGTWSVSNYGSLVDVWAPGVNIVSADYASTTGYRSMNGTSMAAPHVAGLVLNLRSHSNLITPAEITSAIIEMALKGTISPFAEKDGSNCLVSSDMFYSNSSSTPSPSTTTSSAPLSTGTGSYAPHRTGSYSAASGGGKSSSCSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD61</accession>
    <name>A0ABR3ZD61_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Flavodoxin-like fold protein</fullName>
            <ecNumber evidence="3">1.6.5.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PST2</name>
        <name evidence="3" type="ORF">Cpir12675_001825</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WrbA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.5.2" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000031">
        <property type="protein sequence ID" value="KAL1898621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003955">
        <property type="term" value="F:NAD(P)H dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010089">
        <property type="entry name" value="Flavoprotein_WrbA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01755">
        <property type="entry name" value="flav_wrbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002999">
        <property type="entry name" value="PRK03767.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30546">
        <property type="entry name" value="FLAVODOXIN-RELATED PROTEIN WRBA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30546:SF23">
        <property type="entry name" value="FLAVOPROTEIN-LIKE PROTEIN YCP4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="2">
        <location>
            <begin position="4"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="203" mass="21220" checksum="50A95239E4801D95" modified="2025-10-08" version="1">MAKIAIVYYSMYGHIGKLAAAEQKGVEKAGVTVDLYQVPETLPDEVLAKMYAGPKDASIPVLSDPKTLDGYDAFLFGIPTRFGNFPAQWKALIDRTGGQWASGALAGKFAGLFVSTAGQGGGQESTCLAAMSTLAHHGMIYVPLGYSKAFPQLTSLTEVHGGSPWGAGTFASSDGSRQPSALELEIAEIQGEAFGATVAKHFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDG1</accession>
    <name>A0ABR3ZDG1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ph-response sensor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RIM8</name>
        <name evidence="4" type="ORF">Cpir12675_002070</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arrestin family. PalF/RIM8 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000036">
        <property type="protein sequence ID" value="KAL1898121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF161">
        <property type="entry name" value="PH-RESPONSE REGULATOR PROTEIN PALF_RIM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="3">
        <location>
            <begin position="380"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="255"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="607"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="658"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="719"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="909"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="611"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="625"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="664"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="756"/>
            <end position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="933" mass="100759" checksum="B1466C97E16069D2" modified="2025-10-08" version="1">MSRVQQHHQQQPPRDSANSNPQPTTTTTTAANGHSNAIPPSPAAAGPNPTSSNLSSSKPAGGGSSSGRKLFSRFRLPFKSISRTLTDFHIMPKEPYKVHTSGDVIEGWVVLVIEKPIRITHLTVALHGYVRVFKTTAAVRETVAPPLGQLDSPRNHSNGYASLFQDEQVLSGEGKLDRGRYRFGFRLLFPNRTLPSSIDFERGTICYDIVATLTRPTTIGPTVQCNRPVLLVEKIDIGVVKTPKMKSVVLEPISKSRRKTRRRMGTGIDKPPIETISAAGHDQNTAENETNLVASATADVEDAESAHQSATGDGVLYARGSEQGDVLSEASVETGTASTGTGTGTGTAISYRLGDASGLSNAGSGTPANSHISIKTANVEKNTIRADLELTKGGFLPGDTITIRISVQHIRRMKSMHGIIVTLFRHTRIDMSPPDALFDPRLTKEELKKLTNDETFPKSRAGIAGLSLSSTTSLSVFRKDLRQNVLPLIINPATLEYSVPVAVRVPEDAFPTISNVPGEMVSFKYYLEVVVDLGGRLSNQFQSGATSSALLAMPRAPPSTDTSLQAAQGNMMTAPVDTSELKREKGVIADWFEVVIGTTDGARDAKRVKAAQDQADAEAQLQSDPQVQQSSQHTLSLTGQDDIIAGWKYDSKRPILPPRFNDPLLPPNHPSNLPPPPPPPLPPPDIAPTNGMAPHYVPNPHVFDDSVLTEKERIRRHEQILLPSHAPTHDDDGSGASPSRAMSPSAPPDDDDIYGLHSALSAHAAASSLRGEPSAPTLDDLDALHDPPPHHPQATRLPLHTQPLYVPPLSQTLHPPFPRPLAHHSRMPPPTHTNAPPLAIEDKQELERLRLLNEASRPPELPEDYDAGEGSSSTTVLFHASAPDTIEPSAPLLDDESIFGHIHISSMGSGPLEYSQRHMRASSNHDQLPAYER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDR8</accession>
    <name>A0ABR3ZDR8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Elongation factor EF-1 gamma subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">TEF4</name>
        <name evidence="9" type="ORF">Cpir12675_001942</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000033">
        <property type="protein sequence ID" value="KAL1898397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03181">
        <property type="entry name" value="GST_C_EF1Bgamma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03044">
        <property type="entry name" value="GST_N_EF1Bgamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1010">
        <property type="entry name" value="Translation elongation factor EF1B, gamma chain, conserved domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050802">
        <property type="entry name" value="EF-GSTs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001662">
        <property type="entry name" value="EF1B_G_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036433">
        <property type="entry name" value="EF1B_G_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43986">
        <property type="entry name" value="ELONGATION FACTOR 1-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43986:SF1">
        <property type="entry name" value="ELONGATION FACTOR 1-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00647">
        <property type="entry name" value="EF1G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01183">
        <property type="entry name" value="EF1G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89942">
        <property type="entry name" value="eEF1-gamma domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50040">
        <property type="entry name" value="EF1G_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 9" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="7">
        <location>
            <begin position="2"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="8">
        <location>
            <begin position="86"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="EF-1-gamma C-terminal" evidence="6">
        <location>
            <begin position="249"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="216"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="219"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1898397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="409" mass="45791" checksum="918CAFBF7CA5D2F3" modified="2025-10-08" version="1">MAFGKLFTVAGNSRTTGILAVAKANNIDLEVVEAQIGNATAEHLDVHGLGKIPALITEDGYKLFESTAIAIYIASQNEKTTLLGKTKQDYASILKWMSFFNTEIATQLARWTRPLLGAEPYNKKNVEDAQAATLKAISVVEAYLVNNTFLVGERVSLADLYAAGLISGGFEYFFDVKFRQEYPATTRWFSTIIAQPIYSAVATPLEFLETPKLTNTAPKKADAPKKEKKAEAPKPAASAAEEPAEAPKAKHPIELLPRASYPIDEWKRFYSNNETPDAMKYFWETIPFEEYSIWKVQYKYNDELTLTFMSNNLIGGFNNRLEGSRKYLFGSASVYGENNNSVIQGAFVIRGDKFEPVFDVAPDYESYEFTKLDPKNEADREFVDAQWSWDRPATVDGKEYAHASGKVFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE60</accession>
    <name>A0ABR3ZE60_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial oxaloacetate carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">OAC1</name>
        <name evidence="12" type="ORF">Cpir12675_001960</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000034">
        <property type="protein sequence ID" value="KAL1898335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051508">
        <property type="entry name" value="Mito_Carrier_Antiporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45928">
        <property type="entry name" value="RE38146P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45928:SF1">
        <property type="entry name" value="RE38146P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="2"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="107"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="208"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1898335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="310" mass="34045" checksum="5F50B68F35353CBB" modified="2025-10-08" version="1">MSTTLGGFIAGGIAACGAVTATHPFETVKIRMQLQGELQTKGHQPHYYRGPMHGVTVILRHEGVKSLYRGLGAAYVYQILLNGCRLGMYESIRSTMTHIVHGGDSKQSLLINLFSGASSGMVGAALGSPFFLVKTRLQTFSPFRPVGTQHQYRGAWHGLKEIYATEGIRGLYRGVGAAMIRTGFGSSVQLPTYFLAKRMLQKHAGMRESPTLHLTSSAVSGFAVCCVMHPPDTIMARLYNQNGNLYKGVFDCLGKTIRTEGFFAIYKGFVPHLARILPHTVLTLSLAEQTMKLMRKVESRILDEKTMKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF83</accession>
    <name>A0ABR3ZF83_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphatidylinositol-3,5-bisphosphate 5-phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">FIG4</name>
        <name evidence="6" type="ORF">Cpir12675_001679</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000027">
        <property type="protein sequence ID" value="KAL1899019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043573">
        <property type="entry name" value="Fig4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45738">
        <property type="entry name" value="POLYPHOSPHOINOSITIDE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45738:SF5">
        <property type="entry name" value="POLYPHOSPHOINOSITIDE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAC" evidence="5">
        <location>
            <begin position="201"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="734"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="781"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="744"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="781"/>
            <end position="809"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="942" mass="106933" checksum="D985C81E0F2CC7C0" modified="2025-10-08" version="1">MPPEDIAAQTFKPSLPISTVGPSPEDIDSCVWSDSQDDAISLASTQTHLGGSQTKGNQPFNFHKFGLYETASRFYVVGSDVTENHHRVLKIERTSEDSELSIADDKTVYTRNGINELLETIEDGNRATGGIKLRSTIWGLLGFIRFTGPYYLVVITKKSTVALIGGHHIYQIEGTEIIPLTRCKNKQDHRNAEESRFLNIFTSLDLTRTFYYSPSYDISHTLQHNISREREMLTTQLPETGNNGFNSMFVWNSHLVKPTESCIENPYIWCRAIIHGYIEQSALNVFGRIVHITLIGRRSRHYAGVRFLKRGVTEKGHVANEVETEQIVSEALTTSFHSPGPELYSNPHFTSYVQHRGSIPLSWTQDASGVSPKPPIELQVSDPFYSGAAAHFSNLFERYGTPVYVLNLVKARERIPRESKLLDHYIQATSYLNQYLPDDSKIIHTAWDMSRASKSRDQDVISTLESIAEDTILKTSFFHNGSASSSVTFPRVQNGVVRTNCIDCLDRTNAAQFVIGKRALGHQLHALGVLPDTTMDYDTDAINMLTNLYHDHGDTIALQYAGSQLVNTVETYRKTGSWTSNPRDMLESFKRFYNNSFLDTQRQQTYNLFLGNYVYEPGKSFLWDMHGDYQLHNPMPDKNEELATKDYMNWFNPQHLQPRQIPLDYRLTLASRGRCSIDHVDNYWVEYYRPLTLSTFNNMFAFRMKSTLKEGQAASRPSESLVNMSPFQVRIGPEANAPLKRHPEKSVIENNLKDEDTEGTSTRGSSLQQWFHTSNSQIVQNPASTPASSKIGPTTSNTNVTLVSGTRPQKLTPHEKFESAQSIFAKAVHESLDPNVTVEEKEDYFHYLSHPHSLPLVVSAETPADVEPEYIRFVHGLWQYEGLEPSGTEDLQAYIETMEIGDDPLNVTENDSQKKRYKAYRKWLQGKSFFKQHPAVAWQVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFS3</accession>
    <name>A0ABR3ZFS3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ran guanine nucleotide release factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_001852</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MOG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000031">
        <property type="protein sequence ID" value="KAL1898648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.10">
        <property type="entry name" value="Mog1/PsbP, alpha/beta/alpha sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007681">
        <property type="entry name" value="Mog1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016123">
        <property type="entry name" value="Mog1/PsbP_a/b/a-sand"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15837">
        <property type="entry name" value="RAN GUANINE NUCLEOTIDE RELEASE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15837:SF0">
        <property type="entry name" value="RAN GUANINE NUCLEOTIDE RELEASE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04603">
        <property type="entry name" value="Mog1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55724">
        <property type="entry name" value="Mog1p/PsbP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="190" mass="21024" checksum="52181097A00D6067" modified="2025-10-08" version="1">MANYKSTPLYGGAIVVDLPQLYIDVSNIRTVPDHQEVFIDSNGLTSIVFEINERIGGPGSNPDIDGEALEQHLMDLVGEDNKGNVQVWNKKATSFNHLNSLIATDTPPQNDHSIKGPVFTGLIMILLRLENKGTDILITINVPHVKGEYDEFQIDLQAGKQGSKIKQAIQFADQIRETFDIKDYALFGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFZ9</accession>
    <name>A0ABR3ZFZ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001319</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000020">
        <property type="protein sequence ID" value="KAL1899643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="338" mass="39230" checksum="1B434CD601E74E8C" modified="2025-10-08" version="1">MSSLGLIGTIKNERLLLFGMTAYAVTMVGVMWSMLNSVKEDSVLEPIQVKTQYITQETEDALQLHTIEKLADHPNYSIRDISLKILSDRAVEDGNTLKILIVGVTKRNYETRLRCLQSLALIITNTYGSQNPLKKLYNQRSYDAFVRCLELSLEDSVIPKLDNSTWDEHNLRDETEKLALSFLYELTTPENIHLLLQSKFIKKWLVKQNWGDSDEERQKNFHEYTNKRNRVADIIRCLQKTVSGMDALRRAGLVPFQTNNEMDIVPGLQSCASCKSHWDDMCAMDCRSRDRIVHSRVREQSEEEVRLRRQNREAMVFNDGTRPIGREDIIERRRDDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG30</accession>
    <name>A0ABR3ZG30_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001666</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000027">
        <property type="protein sequence ID" value="KAL1899006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03676">
        <property type="entry name" value="NUDIX_Tnr3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031804">
        <property type="entry name" value="DUF4743"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13622">
        <property type="entry name" value="THIAMIN PYROPHOSPHOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13622:SF8">
        <property type="entry name" value="THIAMIN PYROPHOSPHOKINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15916">
        <property type="entry name" value="DUF4743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="131"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="334" mass="37943" checksum="C4AF65B125DB855B" modified="2025-10-08" version="1">MTQLTNLDILNNVDNYPQHATNAIECERPEKSHYCLLFEDIQGRFSVGFLASQVVDALTKLPTELASGIEIDHQNKTVLAFTEPTESERTTHVAAIVQHWQSHRVFKVLKHFRNEMWPVYGRDGITVLYSIERVAVGLFGANRYGAHLNSWVRSSDSRGGIKLWIGRRAADKPTYPRMLDNTAAGGMVTGEDPLECIIREADEEASLPESIIRQNIIPSGFISYIALTHSKHEDGGELRLLYPECQWIYDIELPEGLTPTPKDGEVEAFYLWTVDQVLDQLHQGNFKPNCGLLLLDFFIRHGIMTKDDDPDFDEIKARLRRPLPFPGPHEHIQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGA4</accession>
    <name>A0ABR3ZGA4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Expansin-like EG45 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_001239</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000018">
        <property type="protein sequence ID" value="KAL1899740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22272">
        <property type="entry name" value="DPBB_EXLX1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.760">
        <property type="entry name" value="Expansin, cellulose-binding-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007112">
        <property type="entry name" value="Expansin/allergen_DPBB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036749">
        <property type="entry name" value="Expansin_CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049818">
        <property type="entry name" value="Expansin_EXLX1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041144">
        <property type="entry name" value="expansin_EXLX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF21">
        <property type="entry name" value="EXPANSIN-LIKE PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49590">
        <property type="entry name" value="PHL pollen allergen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50842">
        <property type="entry name" value="EXPANSIN_EG45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046421280" description="Expansin-like EG45 domain-containing protein" evidence="3">
        <location>
            <begin position="17"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="Expansin-like EG45" evidence="4">
        <location>
            <begin position="273"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="238"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1899740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="456" mass="46990" checksum="6415EC0215BDC7CC" modified="2025-10-08" version="1">MRTTTVLLAFSGLVATAPSGPHGDHRFGYYNSNSNNTKYDTNHTWKGYRESMTAPSGFPRGTGYTASSGFAPTGGFAPGAAHTQSSVPTLAMSKDASSNAGSGPDATSPEYGTGPVVAEQVDPVVAKSTLTSMITVPYPASTTPAYGVAAVSSITRTKCQGGNHTLSKVTSVSTQAPVIPVQASTSNTIKTPTALSSTSTLNVEYGISSYLATSSSAAVSSQQPEASSYASAASSSAATAGPQASSPATPGQSSLGDSKTDGKATFYGGNLSGGTCLFTEYTIPSGLSGVAYPTPDWDNAGNCGACLEVTGPNGNTLTVMVVDSCPSCEAGHLDLFSDAFLQFADASAGEIGVSYKFVTCGITSPIVLHNKSGVSAYWFSMQVVNSNEPVKSLEVSTDEGATWEATKRQEYNFFEKNTGFGTEKVDVRVTSETGKTLIIKDVSIESDSRKTCDSNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGH6</accession>
    <name>A0ABR3ZGH6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">14-3-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_001444</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000022">
        <property type="protein sequence ID" value="KAL1899407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.20">
        <property type="entry name" value="14-3-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036815">
        <property type="entry name" value="14-3-3_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48445">
        <property type="entry name" value="14-3-3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1899407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="312" mass="34971" checksum="5A6B5420D7FABAB6" modified="2025-10-08" version="1">MASSEVDQKFLGRLAKAVEPENHLLSEMLFKILGLSLNLAEQLVLAKKQRRQATLSSPEYLKRVWHIIWLSREGLKMLEQYVLPMVSHYRELKVLAYKLRASFYHIFVLFYNNPPVSDMSISEVVISHASNQPKRDAKGKGKAMARDDDLESISSSIQPTHPLEGGPSLRPPPGFELVNPKAIEFSPDFLISATNYLPLAQRYFIEAVKISEELLWGSHSLRLSVKTEYAAFLYECVHDVEGSRQLAKATISEVYDAQEGMDDDMFSDACELVTVLGRMMKRGLGPNGSVRNKPVPLASQVAVPLPGMENPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGP3</accession>
    <name>A0ABR3ZGP3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001408</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000022">
        <property type="protein sequence ID" value="KAL1899372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="2">
        <location>
            <begin position="862"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="567"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="647"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="647"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1138" mass="124579" checksum="CDA15F04E406657F" modified="2025-10-08" version="1">MAGPSSSLARLPKQALNTILEVVEDEEGVFPELSHYKKQAQQKRHELNQIRQWATGNGQDIHNQVLVKQWMSPTSDHFPTPRGFPTPQGVHFMLAPTLPSSPSVTSDEEAHESEDEFIQMGYWRQPSPTAAHSVNTSDAALYRPVWGNSQSSSRESVMSDTTEFDDLYEVSDDETRTPRLSRHSGLDSSNTFSIANTRSSLEETSKVLAPLIIPTHTANSANVALSAKSVKDFLSPLAAVPTPTTAIAMSPAVMDLMALRQAQALLPMSATPSLDGSQTSDALAAMSAPPTPIMGNDEDNDAACEWHGVQLQPEAFQTLQALVTSQPAAMEAAEEAQQHMVEISQESIVEMPQMQTREIDSSFAAPSQMVQVEGDNSNDGGDGHDHDDDVKLVALEMREMFQELSMALFTSPAPHRSSVPALPVAGSHSASVSARSSWAGFTALDIPSPGGFFRDLSPRTRHAWESYFPITKAEPEALTEEALSSPTSAAAEQYYKTPWNSHISNGSELHQPQLRDSIPPVPPLPQVWGLPSMPSKVHSDTNTVGFTLTRPCKPIEHVVEIDLAAFHDDDDQPTSRPVYAPSNASGEPKLEEEIEATPELTEIVTDCNPEYARKQQAVALANLDRTEAWLSAQKAYLNGTCHTDVSLSPSSAKSQAVTSTPEEPEVPAAESQLIKKTYKEAGTARKTVRFSLTTIQSDMPCQLPSRLARHESAYYRAFLDYLMRARPQDAFVHRTARFEAIQAQRVSLPRLHRNLLFGKLQLSVLPQSAQKRLSANVARADAEIIDDPSRLRREREAEAMMQMAANTWLVQTVKMLNGGTLFSRPVASYLETRRAKKHRILDISTAVVGEWAWHAALAYPNAKVYTVTTKAARQLSNANISGPSNCYNVAVERLTKLPFADNYFDAASARDLHSLLKAAGENGEDEWNGCLAEIMRVLKPGSMLDFSLLDADIINAGPLGLAKSVEFGFALKTLGYDPAPTKPWLSRLHKAGFSNVRRTWLCLPLGERRQRQRPNLSLIIPSTSGSPFGAIPQTPGGTGKTLAMQAMVSEDKTTGSTDNIGAMCGMLGAWNWERWLLRCEMEKVASELRLCDTTNTSEAMLEAERCLEGVSSVLEEGRNCGSAWRMLVGCCQKPEATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGT0</accession>
    <name>A0ABR3ZGT0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ribosomal RNA-processing protein 17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_001438</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRP17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000022">
        <property type="protein sequence ID" value="KAL1899402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019186">
        <property type="entry name" value="Nucleolar_protein_12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14577">
        <property type="entry name" value="NUCLEOLAR PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14577:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09805">
        <property type="entry name" value="Nop25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="91"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="163"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="163"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="187"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="197"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="208"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="223"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="236" mass="27256" checksum="113B3E4521EDE038" modified="2025-10-08" version="1">MFAIPRPKKGLGIAPKKRGRPSAVEEVVFDKEARHEFLTGFHKRKLQRQKLAQETAALREKQDKIRLRKQLKEDRQKQVEDHVRTVKEMLMEHHMAGNLDSDDEANQEWDGIAESDQANDEDDANSTTPKLAPGDEIVDIEEEYIDEDKFTTVKVESVMVTRDGLHKPGAEEAEAAEKRARAIAAAEEAKKNEKPKKQWPKKDKKAKFRYENKVDRSEVRARQAARNKAKRRNHEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGY3</accession>
    <name>A0ABR3ZGY3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">R3H-associated N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001523</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000024">
        <property type="protein sequence ID" value="KAL1899325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02325">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025952">
        <property type="entry name" value="R3H-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13902">
        <property type="entry name" value="R3H-assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="R3H domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="R3H-associated N-terminal" evidence="2">
        <location>
            <begin position="145"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="444" mass="48502" checksum="BB7FDAABB420DB2E" modified="2025-10-08" version="1">MPPPTPPRRRMAFNYDSDDLWIPATAVSSAPSVSAASETDRSTWAIPSDPPTPQLAGATLSTPALDGAVSVPRAPAATTAPVDIEAWSASALQSLSIATVQTGADGAQLQIPLVDPPMSAPVPVTRRMPAAQIAASHLIPRRAPPTKRELMVKGNEGSRARRRWENNNLVHVPNVTPPSAEDMLPRPTHRMATVPYQVASDWDTAPATGHGRTSLLRDQAAFKFAAAAYARKTQQLLSGLATGLAKGEVPRDLRETAKRSPVVRAWVRALEEPLRKWVAEQKNIEGGVLAETDVETETEVETEVETEAETEAETDDEGWVRVDGDNFRDGEDVVLYTGRRSAKEVSDPHKQAPAMVFDSIGDDETAAFKRWLAHAISEYYGLESYSVTLANPTRRVVYVGASQPSTAEATDKNKTKKKRRKHMNHMHARLRNAELPRPLWEVVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHV6</accession>
    <name>A0ABR3ZHV6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Xylose isomerase-like TIM barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001312</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000020">
        <property type="protein sequence ID" value="KAL1899636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050312">
        <property type="entry name" value="IolE/XylAMocC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12110">
        <property type="entry name" value="HYDROXYPYRUVATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12110:SF21">
        <property type="entry name" value="XYLOSE ISOMERASE-LIKE TIM BARREL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="Xylose isomerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylose isomerase-like TIM barrel" evidence="1">
        <location>
            <begin position="81"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="404" mass="44809" checksum="98CAF99D51AB6D92" modified="2025-10-08" version="1">MDNTLMCIEDSLLTSKKRQNPLRIVKSTTVFSGKPGFIPCIGTMSLGKPSECPLLAKLRPDFVDFVKRSFGPDIASYTRAACVVRDYSNRLGLTIISVQPFTNFDGLICPEEKKRIKTAFTDVWVEISDILDVKMVGVPASYGNDEDSLSGNPNLISQDINWISKVLWKSPGVKVGYEALCFSKWITTWQAALKIINDSNYKSVTKGRPPSTKLIIDTFNLCGSTIANPTTPKGLEMNGHLILGKSLHDLKKAVAVNKGIICLVQVADAKRLMSRTSHSHGISEKEAKMNWSRNHRLFPGEKKRGAYLPVLEILREITNPDGIGYKGYISLEVFMGPHNEELIDKMYHSMAASYRLDHAGALALPTAVALECGHRARTSWMLLCAELGWQSDWTPKIGVVSDEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ96</accession>
    <name>A0ABR3ZJ96_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA (cytosine-5-)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_000840</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.120.10">
        <property type="entry name" value="DNA Methylase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050390">
        <property type="entry name" value="C5-Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10629">
        <property type="entry name" value="CYTOSINE-SPECIFIC METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10629:SF52">
        <property type="entry name" value="DNA (CYTOSINE-5)-METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="315"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="368"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="315"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="369"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="398"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1900706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="415" mass="47659" checksum="26DACE73B84C0049" modified="2025-10-08" version="1">MRVGLHLKYAVDAWDLACDSYDKNFSKVNLFRMKIDEWICRSAPQETSDNIESRTRFQCDVLHLSPPCQVFSPAHTINSQEKDEANFAAPFSCEVILARVKPRVLTFEQTFGLLHRHWRPVFNNLIASFTRLGYAVRWKYVFLPEWGLPARRKRLIVIGAAPGEPLPTFPPPTHSYRSWETGLLPLVTVRQALGKLNLQRDDPLHRPREMKRNNMPCWNNKNTLTRCVTTSGGQNHHYSGKRCFTTRELALLQGFPMYHEFVGAFQTRQIGNAFPPCAAAVLFKHIEKCLLAADGVTVDEGDQSLAYAMAIELEDEDEGNPIGDDDLDFTSSSEKGEGGYDDYDGEFSHPFLFSRQEYLGHTDKCLNTLRPSRSQPQSRQWGKTYDLTQNESEDSDKFEDWRQMLEPDTLTRKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJC4</accession>
    <name>A0ABR3ZJC4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">mRNA-decapping enzyme-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_000873</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DCP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010334">
        <property type="entry name" value="Dcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16290:SF0">
        <property type="entry name" value="DECAPPING PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16290">
        <property type="entry name" value="TRANSCRIPTION FACTOR SMIF DECAPPING ENZYME DCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06058">
        <property type="entry name" value="DCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="180"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="196"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="248"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1900736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="271" mass="30704" checksum="C1C45FCBF19E8C47" modified="2025-10-08" version="1">MSQQTPRRYPKHKRNPSANRVSDYESDAPYVVDTTPNPKLANRTNTEVNLKVIRNYLPDVNHINYCNANAVVYGFNTAQSEWMRTNIDGPLFVCQSGTSGATVQINGYIFILNRKNTENRVYSFRNIIDIDITSEYLILIMDEPGNDAVGIWVHAANDADRIASMKKIRDVIMEVKNAASPSASASSAPPPVPGVQAPLQQQHQQPQQLQSQTDASNQYQYQNQHPPYMYQPQPQQQYTEQYSGQYAPQFQGQPDGTSQKIDVQMLFDRQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJG2</accession>
    <name>A0ABR3ZJG2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Metal homeostatis protein BSD2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_000795</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22212">
        <property type="entry name" value="NDFIP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019325">
        <property type="entry name" value="NEDD4/Bsd2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13396:SF5">
        <property type="entry name" value="NEDD4 FAMILY INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13396">
        <property type="entry name" value="NEDD4 FAMILY INTERACTING PROTEIN 1/2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10176">
        <property type="entry name" value="NEDD4_Bsd2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="257"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="18"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="115"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1900781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="355" mass="37941" checksum="C1F0DEE5BA533C3D" modified="2025-10-08" version="1">MAPQQYQPVHAHDDEITHSTPTRLPSRRSATCPSSPPSFHSRPSSPERSHDVDPDLADAFGGDSDSDSDSAGEADDRQRLVRRAPTATSISALDDDENDGPVNSGPQTSIPETRSAAAARAQPSVATSARAGSRVYGGGMASDGVFSNLAAKPDMGEEKEEMPPTYEQAAADQAPPYWETTIIAPGYNGDNEVYIDGMPVGNIFGFLWNAMVSWSFQIVGFLLTYLLHSTHAAKNGSRAGLGVTLIQYGFSMKAAAIPPTPEDGNSGNSEFPTPPDPNAHNFNPSDISSSSSGWSDLTGTEWFAYILMVGGWFMLVRSVVEFLQARRHESLVLQSPERGLSVPVVATGETPDRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKH0</accession>
    <name>A0ABR3ZKH0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">G4 quadruplex nucleic acid binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ARC1</name>
        <name evidence="6" type="ORF">Cpir12675_001140</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10304">
        <property type="entry name" value="GST_C_Arc1p_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02799">
        <property type="entry name" value="tRNA_bind_EMAP-II_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053836">
        <property type="entry name" value="Arc1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051270">
        <property type="entry name" value="Tyrosine-tRNA_ligase_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586:SF33">
        <property type="entry name" value="AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586">
        <property type="entry name" value="TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21972">
        <property type="entry name" value="Arc1p_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="5">
        <location>
            <begin position="198"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="141"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="141"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="161"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="174"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1900034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="391" mass="41283" checksum="49BA61A02B177CAB" modified="2025-10-08" version="1">MASISSQKYTPAEDKDIASWITKAATVSDAAVLAELNTHLATHTTVLGTKPSSADVALYKALAPIVAGWTPEQRTGEAGLPHIVRLVDFVQNSALFELSVAGDAKVAVNADEILYVKPPVDAKAEKERLKKEKAAAAAAATNAAATGETKVLPDRTKNPKDAAAASAPAAADQAKPKKEKKEKQPKPQKAPAATTPPAPSLIDLRVGHILKAIQHPDADSLYVSTIAVGDKAGDDYVEYEGQLCRTVCSGLNGLIPLEEMQGRKVVVVCNLKPVKMRGIKSCAMVLAASPKLKEGETDDHKGPVELVTPPADAKAGERVYFEGWKGEPEGVLNPKKKIWEMFQPGFTTTSDLEVAFDAAVVKELGKEGLGKLVTESGSVCKVDSLVGALVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKM0</accession>
    <name>A0ABR3ZKM0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">DNA damage-binding protein CMR1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_000801</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">DNA-binding protein that binds to both single- and double-stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the WD repeat DDB2/WDR76 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050853">
        <property type="entry name" value="WD_repeat_DNA-damage-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14773">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14773:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="363"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="30"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="542"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="564" mass="60749" checksum="C3428B1F2D1E5DC8" modified="2025-10-08" version="1">MPPKDPPMSAFERRRLENMAANTAILKDISITAKKVAPAKPKARPAPAARSQSTRKRPRSETTSSPAPTSGSASAPALATARVTRQSSRLAGINAGDIPGQAVLAAQLDASADASRAKRLRVSGDLQLDSVVVDGKKWSNSSAVGLRDLVRGAQPGVRTFTAEDVAETTDEGLKKLREELGRMELYETWAPGDIKITPQRVYALGFHPTEDKPLIFAGDKEGALGVFDASQEPIKAEDDEDAEETYESPSILAFKTHTRTISAFAFSPFDSNSVFSASYDSSIRKVDLSRGLSVEVYSPAQTDIDMPISALEIMPSDPTVLLFSTLSGSVCRADTRKPGIVDEWTLSGQKIGGFSVHPLQPHLLATASLDRTMKIWDLRKMVAAEEEDDSSHSGEIPALLGSHSSRLSVSHAAWSAGGHVATSSYDDTIKIYDFSQSCGAWKPGAALSTEALEPTHVIRHNNQTGRWVTILKPQWQRTPRDGIQKMVVGNMNRFVDVFAADGSQLAQLDGEGISAVPAVAQFHPTLNWVAGGTASGKLCLWQSGGGEKEEKEEERETETKAKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKV0</accession>
    <name>A0ABR3ZKV0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000524</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="296" mass="31552" checksum="63F603C191B3744B" modified="2025-10-08" version="1">MATLPSGHGQISDQGPDACGPSSSSPETSSTRLNPFADTESARKRRRMHGSASHSLSEDSDSEIGSRSTEKTPQTSSTPDPVSRQSPILLSTGDLPISRPSGIPSPHANDSPQQPTIIMSDHETQAPSSPVQISPTSLCSINTDRPETPIGAPSNRVTINIRPTMANAQSSSPSLPLINHSQEGQDPHLIEADGSASIKNSVELDGDVEMISNENDLDSPRLDLDIDSDDDILRAGAASIIPDIPTIIFDPTNDFPYCENQNHGENISRVCEFLTYGKLPRTITLILQSCLANVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLB9</accession>
    <name>A0ABR3ZLB9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Exosome complex protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_000575</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for exosome-dependent processing of pre-rRNA and small nucleolar RNA (snRNA) precursors. Involved in processing of 35S pre-rRNA at the A0, A1 and A2 sites.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the C1D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011082">
        <property type="entry name" value="Exosome-assoc_fac/DNA_repair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007146">
        <property type="entry name" value="Sas10/Utp3/C1D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15341:SF3">
        <property type="entry name" value="NUCLEAR NUCLEIC ACID-BINDING PROTEIN C1D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15341">
        <property type="entry name" value="SUN-COR STEROID HORMONE RECEPTOR CO-REPRESSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04000">
        <property type="entry name" value="Sas10_Utp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="155"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="165"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="204"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="222" mass="24096" checksum="A2C9544FB370355B" modified="2025-10-08" version="1">MSVRDITKDLNKLDKQLEALDDALKPLLKALNESASSMLLLDRAKLFTLANYALETLIFAGLRVDGADAMDHPVFKTELMRVKQYFAKIEAVEKPAEAEAVTSQQQQPAVRLNTEAATRMIKHGLSDDAALKAKLAEQVAKEKAKAFMRSFGSAKRALTKDDEPSTTPVAAAASQSTNSKTIGDGSELNSGGGVKTKKSKSRSNEASQQERSTTVAKRRKQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLD2</accession>
    <name>A0ABR3ZLD2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ribosomal protein/NADH dehydrogenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_000601</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I NDUFA2 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016464">
        <property type="entry name" value="NADH_Ub_cplx-1_asu_su-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007741">
        <property type="entry name" value="Ribosomal_mL43/mS25/NADH_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12878:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12878">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE B8 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05047">
        <property type="entry name" value="L51_S25_CI-B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005822">
        <property type="entry name" value="NDUA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00916">
        <property type="entry name" value="L51_S25_CI-B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Ribosomal protein/NADH dehydrogenase" evidence="10">
        <location>
            <begin position="20"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1901235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="93" mass="10227" checksum="27DAABAC38CB7AF7" modified="2025-10-08" version="1">MSGKYAFNTAVKELRFLFCNASDKGAATRTFLNRAYPTMKKNNPNTPILIREALGTPSRVFARYDLGVEKTQSLEGLSDKQIEDAVVGLVKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLS9</accession>
    <name>A0ABR3ZLS9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000922</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="303" mass="33443" checksum="0AAFF8112E63836A" modified="2025-10-08" version="1">MDSNDLSQPVLAASNHQPSSRISFVDAHLHMVLQRYQDYHDQRGIQVQLEREVSQLRSYMSPAATDDQPVDDNSRSSRHSARSAHERSTLLRARYSERTPSLIRDSSSGSNGGGRSLRRLPESRRIKIGLVIDPVLQMPCFAVTSRSARAAGVPEVELAAINFILALEFPCWEHFHREDFHHNLRHADPCGPRHESGHLMMASALCLMTASSSVFSMLDEIAHCGTAHDYIGNQARSSATWEGRGLSYKTLRSMVCSTNNSGTRDIRSTIELTPAQAWFELESKVAKASSAQAPTSMTGALGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM52</accession>
    <name>A0ABR3ZM52_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Chromatin remodeling complex Adenosinetriphosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ISW2</name>
        <name evidence="11" type="ORF">Cpir12675_000408</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17997">
        <property type="entry name" value="DEXHc_SMARCA1_SMARCA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1190">
        <property type="entry name" value="iswi atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.30">
        <property type="entry name" value="ISWI, HAND domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044754">
        <property type="entry name" value="Isw1/2_DEXHc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015194">
        <property type="entry name" value="ISWI_HAND-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036306">
        <property type="entry name" value="ISWI_HAND-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015195">
        <property type="entry name" value="SLIDE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623:SF49">
        <property type="entry name" value="SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09110">
        <property type="entry name" value="HAND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09111">
        <property type="entry name" value="SLIDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101224">
        <property type="entry name" value="HAND domain of the nucleosome remodeling ATPase ISWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="185"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="481"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="10">
        <location>
            <begin position="848"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="115"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1026"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1069"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1026"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1091"/>
            <end position="1114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1901539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1129" mass="128430" checksum="108B3A4053CCED74" modified="2025-10-08" version="1">MPPRSSRANEVDSDASMIDAPDHNANDTMDVTENSDSESQSVAETTDGRKKRGEANILRKSVFGKRHDSLGESKEDDTIRRFRYLLGLTDLFRHFIDANPDPKIREIMREIDRQNDEAASAKKKSNGRQGGASSDRRRRTEAEEDAELLKDEKDGTNAETVFRESPKFINGTMRDYQIAGLNWLVSLHENGISGILADEMGLGKTLQTISFLGYLRHIMGVKGPHLILTPKSTLDNWKREFGRWTPEVNVLILQGSKEERQDLINNRLNEEDFDVCIASYEIVLREKAHLRKFAWGYIVIDEAHRIKNEESSLAQVVRLFNSRNRLLITGTPLQNNLHELWALLNFLLPDVFGDSEAFDQWFKGEDRDQDAVVKQLHRVLQPFLLRRVKADVEKSLLPKKEVNVYIGMSEMQVKWYQKILEKDIDAVNGAGGKRESKTRLLNIVMQLRKCCNHPYLFEGAEPGPPYTTDEHLIDNSGKMVVLDRLLERMKKQDSRALIFSQMSRQLDILEDYCVFRGYKYCRIDGGTAHEDRIAAIDEYNKPGSERFIFLLTTRAGGLGINLTTADIVVLYDSDWNPQADLQAMDRAHRIGQTKQVVVYRFVTDKAIEEKVLERAAQKLRLDQLVIQQGRAQTASKAAANKDDLLSMIQHGAQDLFNSKAGTGVIGGTGGKIDDTDIDDILSRGEARTKELSAKYEKLGLDDLQNFTSESAYEWNGENFNKKKNEQINMTWIEPAKRERKEQSYSMDKYFKQAMYPTAAKSEPKPKAPRAPKQAAAHDYQFYPHRLRDLQERETAYYRKEIGYKVVLADGDESTLEERENELALDQQEIDGATPLTAEEIEEKLELAEQGFDWNRRDFQQFINGSAKYGRHNIEGIAQEVDSKTPAEVRAYAKVFWQRYMEIADYGKYIKIIEDGEERMRKIEHQRRLLRKKLSMYRVPLQQLKVNYSVSTTNKKVYTEEEDRFLLVLLDRFGIDREGLYDLMRDEIRESPLFRFDWFFLSRTPVELSRRCTTLLTAVVKEFEDAASSKGSGAASPTGNGINGKTKREDSDNEEDSVLELAPAKKRAKAVAAAAAATSNGVKNKALDNVKSKASSSKATSTSPSRASSVASTSSNQGPASKSKSKSKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMS5</accession>
    <name>A0ABR3ZMS5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7727 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000222</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056144">
        <property type="entry name" value="DUF7727"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40629">
        <property type="entry name" value="PRO41 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40629:SF1">
        <property type="entry name" value="PRO41 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24853">
        <property type="entry name" value="DUF7727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7727" evidence="2">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="144" mass="16233" checksum="4A215FA0569F756F" modified="2025-10-08" version="1">MGRLIKNHWARLIVLTAATYQVAAGINGFFWPKIFWDFLTTSLDSAVKPIPILQIANIVFGVFMFALEWPMPLIAGTGFHRSIEFRLAFLPLVILAAALLYSATNAALYYLVGMVAYFWAFSEGEIICAKPWTLPKRNNTNFKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN51</accession>
    <name>A0ABR3ZN51_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000016</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="636"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="657"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="679"/>
            <end position="697"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="725" mass="79637" checksum="C5A3D4044841E41B" modified="2025-10-08" version="1">MIGVMSSLISCDDPDFVLPSIEGPVALPLNNHRRHHGRNSHTRNQHALQHDLLNVNDSHSPNTRYTASCLNTLAPSPTILSTAVQLLTRDGQQRHNAIDQNEFHRNGALYPSLSISSSSSSSEDDEIPAMLPPPQRFSTGKTSGPRPYNPGKRVMPVPPAAKTSKPEACQSKRTVSRTTADAVSESSQPTASARKRSLKDLSFEQDAVLHASTKSKRSKWSATRELQEEAAVLPELPSVAIPVKRGRRQPRNHPLPKQKVENYEPIEGEANFEQRKTSSKVAAVLDHRKSIRQAAPLSGYPLDYEKYGDKSENDNSHFPMEISMSFSHATGIDHGTPPRRPRQPAFMLSQDETDASFAHECIISSALPPTRFSGNAPYSDFKTPSQLALSDLPPPPTPSTTSAPAAYVDANFDLQTRSRNIILDVPGIYELSKAAGADNMAYACQPFQLPHNRSTWPLWRYLSYLRRKFGQLPDVSDTGTHNANANAHAVFLNEHNETLQKAYSGVGVNMIKVLSICDRSIDDQEIRNASPPTIIKDLVEVIIPVAIMVVQTLFHAMELPRGGSPIGIYGAYHQWQKQDFQAEFLDTDETVPVEDTDPGGQSLKSGGHYMFTLRMAHITAQAIGWLEDLDKAASAVGPTAPERATSIGTEKGKDSGEGEETDESDDGFEPVKGFNPKRSRAETKKETKKVPNADMERRKSRGVSQVSKLLGPIRMAVDTALSCLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN89</accession>
    <name>A0ABR3ZN89_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000337</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="13"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="582" mass="64739" checksum="F4D456EB171315CA" modified="2025-10-08" version="1">MSAANNSTSASDVITYIGVPLAVLGVMPILYNTAVTLVVQSNIRQMLRNSKLEGVTRSDVFNRVIEIEIPRYAIKPCDRLRDREEYWSTSRSPSIIPGGSWMTLNWRKRLIGSRTQRVAYTDQVRQPQAEVAFDNLVSYLLDLGAVPEPEGWKILRSNGLWTPVGWDLMKGPSGQKALSIAPLDDSDGNLSLAIAWSSDWTTRDLDSLPPYWILLPPPILPLPKYEVAKEGVDGYGDGESTGQENSGELASSRAENSLGKKPEPKDKEVPQPNATIDTVQQQADANSTRAICCHVSSEGLVEAIPQANHAQAFPLPEPLYIDHLKASSTNLGGIWLASALTAYGVSSNTVLWNYKVPKEIVRLASSPLIPCGVLELLGIVDASQTPDWGTPDVSGQRSLERLARRSRDRVQVLARETQLSPQERMKAQTERMARERQEDFEQFISESAERRRFLDQRRREAFQSPKWAPSLLGDHMLAWLKARHHVPESATVKEATGQSLHGIVVNGVFAKKIFTILELWKDWAANAGMRKEDYDMLQADIESFAWAAVLVAVVSQVGEAVEGRLASDMQECLRMWKYVRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNB6</accession>
    <name>A0ABR3ZNB6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Arrestin C-terminal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_000342</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Interacts with hulA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the arrestin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF17">
        <property type="entry name" value="FI21816P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="4">
        <location>
            <begin position="184"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="477"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="626"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="484"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="502"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="627"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="648"/>
            <end position="657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1901652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="657" mass="71606" checksum="DDBBC365941A91F1" modified="2025-10-08" version="1">MRLKPFSSKKSTVTLFQIRLDNDFIVFRGGEDESSGQVLKGHLVLCLSAPLRVDDIHLDLAGTIRFSWAEARHTGASVTGPPKVDRTISLLSHRFPSFIGGKGKNITLEAGNYEWPFEYMLPGNTAETIECVPEVSLTYRLTATCVRNKLVASDVHTQKRFRVIRTLDPTALEFHHAMSVENIWPNKIEYSLAVPQKAVPLGSHVGLEMRFTPLLKGLDLGDITAKLIEIRECSISTSASPNGKKEYKTERCTETWKFPVTHEAHWRDTIEGTGQEGWYVEKKLPLPKKLRQCVQDLHHHGIKIRHKMKLTVSLKNPDGHISELRATLPVSIFISPSLPMDEQGNLVNQSEGAADSIEEDINANAAPPGYGDHILDQIYEDADNTTTVTTPVAQSGVSSPQFYSQSRIGSSEDLHSYFQPGTASSGASPSIVVAAPPAPAAAATTIATSQNQPTTPATTRHGVLAAALTSRLQEVSMANRRNTSSSSLASLAAAAGIHTSRSQSHSNAHSNGHSNAHSTDGDPASGCQTPDFDPELAMLSQVPSYETAVKTPARSYSYTGGMVLPDYQTVLSAPSTPTTEFHYDSLFTIPESTSRLHASMPGSRTTSSHPSRTTSFTQLHTLHLRNHSYSGSPMPPRTQSSNALSMLGRRRHNDNHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNL3</accession>
    <name>A0ABR3ZNL3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CAP-Gly domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_000265</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18849:SF3">
        <property type="entry name" value="LEUCINE RICH REPEAT CONTAINING 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18849">
        <property type="entry name" value="LEUCINE RICH REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CAP-Gly" evidence="4">
        <location>
            <begin position="22"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="543"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="543"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="560"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1901757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="625" mass="70427" checksum="9EC2AA8E6EFBD409" modified="2025-10-08" version="1">MPFYIGQRLCYDDALCTVRYIGRVEPTTGEWLGVEWDDPTRGRHSGHHKEKQYFTCETEPFSIATTATSLSNSPTAGSFVRPSRPAKPAQSFISAVLDKYTSEVDPETQAIRAAKQIRIGTKMAEEVGFDKIRLQLAKVDQLKIVIVGSYRVAFAVAEGEKSVKEMVPSIQELDVSRNMLESVGVVVDICKDLAHLKSLRMGGNRFRDAMADPGLRNAGSAFAHVKELALNENMMSWEDITCITAHFPELTNLNCSTNQLSILPHLPLGSLVDTLTSLQLELNQLTAISDLSAVTELKVLRNLHLKGNYISTVTKPNAPVPLFSESLHYLDVSYNNISSWDFVDSLLESFPGLMSLRIAHNLVYDTATLGDNPAKAQKTRIDSEESHMITIGRLPQIKILNFVSITADDRANAELFYLSRIARELAAVGKEEEETALKHHPRYQMLCEIYGAPEVTRQNKVNPYFLEARLIKVTFYLVQHNEQSRNHQDIGEEYVRLVPKSFDIYAVKGFLGRHFGVAPMQLRLIWETGEWDPVAALDEADETATLDGEYSSDEEEAEAEREREGALRSEEPSKQHNETKKKMEKDSEASKMRRWIKRQVELNDSTHQLGFCVDGMEARIRVEMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPK2</accession>
    <name>A0ABR3ZPK2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000082</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="639" mass="69801" checksum="AEB73DF21C2F1D01" modified="2025-10-08" version="1">MSIVKRSIPRSSPSGNLPDTRMSPLLLPAVAYRPEHAFESFQLSSAPISSTLCLPGKKENVDADYDSPKTIANLRQDENGNAQVARALNSTNVWSPVPKTRLRASLPPPSLKKSNTHPNRISPRRRPEPIFIPCQNQTDCVTSHASTTICGTDDAKAESHTSPPKRSSRIDGGAAQQAGTSGSFVSTQDYNGKGKANLPTQLIILSKSADISHTAQSPQSQIANLTSGAYTSDHPPSPPAFEPTSLMHQPEPLSQSDSCATSNIPVLPIDHAHVCCRCAVAHAPPQSLALRSRPQMLLLGGMAYDCSEIRLMASEILACRSSGELPFSTAPLTDPKIIVEDWGILQILRLSRGNPNKKPSPDYERLRTEIKKLFTERDSDRSDEAAQNAAKERIRFFLSAAAKEGSELHEILNRSEKTPEAYNNSSANQRSASLNIPKESCMVSHHSAASVPPTSQSFRRKSQPPMGTPAPLTAHLPASAWTPHHTVPPYNSLHSGVSLTTEIQSIIKETVRDTMNEAMQPFQEFREYIACVRDEMSQLVQTQLLTTDRLESMHGSAEVLAEVANAIPMQLEKALGDVQAAQCEGVESLRLEQLHLQEEMVGSIDEAADAIAVDVEQRVRQGLEAQMSMWFSQLEEIHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YBG2</accession>
    <name>A0ABR3YBG2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_006995</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000516">
        <property type="protein sequence ID" value="KAL1885335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1885335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="96" mass="10941" checksum="C01F8F1B1EA79305" modified="2025-10-08" version="1" fragment="single">ELLALRAQVAALQLEQKRPRPALPDVEKYDGLDYHKFRIFMADINEKIAMDSEALGDDKDCLVYIFSRLTGDAKESIGPQMEGFYMMKDPKKAMKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YE21</accession>
    <name>A0ABR3YE21_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Acyltransferase 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006893</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000408">
        <property type="protein sequence ID" value="KAL1886047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050879">
        <property type="entry name" value="Acyltransferase_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028">
        <property type="entry name" value="ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028:SF128">
        <property type="entry name" value="ACYLTRANSFERASE 3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="297"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="381"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="2">
        <location>
            <begin position="10"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1886047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="432" mass="48917" checksum="5127979CF1FCAEB7" modified="2025-10-08" version="1">MAIGKEGNVKWVDGLRGIASALVVITHIARAFDHALFSPSDEKDLPARFLQWPMIRVLIQGRIGVTIFAFVTGYVCALKPIRLSRVGNQETAFVSMGKSALRRIPRLVIPTSIATIMIWVFAQLGVFHVAAHTNSNWLRDTAPQVSPYLGDSLMSLTKNLIMTWTHGANIYDANQWTLLPLLRCSMWIYAFMLGAGFMQPKYRMLASFSLFFFFWLCGDTAFGMPTFFGALMSDIQNSGPANEFVNNNKALSRILSIFFILASFWLGSYPEANANFASWSRDLDSLFSSITMPGTEIHRFSSCMGVVFLVIGLHFAPGMRDMLSNRYFLWLGKMSFAVYLLHGCLMRTALTWLVYGFNVPADTHTETGEFIRGIIDYPGHWHLFMVLIFWIPLNYVVAYMWTSYVDPWAARLTERMVSVVNIPRDEKPRLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YEV6</accession>
    <name>A0ABR3YEV6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000470">
        <property type="protein sequence ID" value="KAL1885979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045359614" evidence="1">
        <location>
            <begin position="19"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1885979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="132" mass="14302" checksum="9FAF97B0B9B6116F" modified="2025-10-08" version="1">MQLIHAIVTLVAASQATAIAFDEDIMARSNIAEAANMKSTRQVKCLDQCSPHPGQNLCHESAPCTYVAGKTPKFYCSCSAGFKPDDISPENAFRLPWSGQESRVFVKPGASCQKPCDNILACTEVAFQPQCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFG6</accession>
    <name>A0ABR3YFG6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sedoheptulose 1,7-bisphosphatase</fullName>
            <ecNumber evidence="1">3.1.3.37</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">SHB17</name>
        <name evidence="1" type="ORF">Cpir12675_006744</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.37" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000366">
        <property type="protein sequence ID" value="KAL1887016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050278">
        <property type="term" value="F:sedoheptulose-bisphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF15">
        <property type="entry name" value="SEDOHEPTULOSE 1,7-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000709">
        <property type="entry name" value="6PFK_2-Ptase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1887016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="224" mass="25301" checksum="70DB34985E1DF535" modified="2025-10-08" version="1" fragment="single">MPTPRLFIIRHGETEWSLDGRHTSHTDIPLTPNGEKRVRATGRALVGRDRLIVPNNLAHIYVSPRRRAQRTFELLNVGSKKSLPWLRHGTQDEERDDLDCEAKIEVTSDVREWDYGDYEGITSKQIREQREEEGIPGQWDIWADGCPGGESPHDITSRLDRLITDIRDKWHKPAMQSQRQNSPAGDVLIVAHGHILRALAMRWVGAELEAGPAFILQAGGVGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFH6</accession>
    <name>A0ABR3YFH6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Spindle pole body component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">alp4</name>
        <name evidence="9" type="ORF">Cpir12675_006730</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
            <location evidence="5">Cytoskeleton</location>
            <location evidence="5">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TUBGCP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000361">
        <property type="protein sequence ID" value="KAL1887041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF13">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="8">
        <location>
            <begin position="210"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="7">
        <location>
            <begin position="549"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="22"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="99"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="131"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1887041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="952" mass="107008" checksum="E78CA149002262C5" modified="2025-10-08" version="1">MAGSRATSRINTTVDPSDRPNSRYQSSTSQAYRSAGTSAGDRGNEHHAGDRGANSRSPSTQFFHGHGGHGSTASSMASSTAHAHKRSASANPSRPHAGRSTEDMRVEERERRTETRTSYQVETLMSRTRTRSPDRRDRRATAQKRPEPKQKDRPAPETPQVLWNPEASIVKHTTAPLASRISMPPSASHYPQPPKPLADLSLEAQEAVIIEDLLFAFMGYEGQYIRFAKVYDPSEERDRLTGPEYRIAPGLDPSLHDLTASMLRMATHYSALQCFVDVQSRDEFGLVNHALCASVRKILHEYLVMIAQLETQFLTNENFTIHVLNVHIKPMSHTLFQIYTLGLELLTKNALLDEDSEEEIDSGDDFENILETLREGSGLGPGNITGKKECKGGVVLGLITQRLETMSGDPAAKKLLTALLQDASRPYMVMLNEWLHHGSIHDPHSEFMIKAKSIRHDRLEQDYIDEYWDSRYTIQQQIVPPQLEAVKEKVLLSGKYLNVVRECGGMDVSTSMADVPTTFDDPKFLENINAAYAHANESLMQLLLTTHALPARLRSIKHYFFLDPSDYFTYFLELGASELRKPIKIVNTGKLQSLLDLVLRQPGSVVSLDPFKEDVKVEMNEVPWTRTLQHVVGITGVDKDEVLPPVSSQPLETDRNATGITSLQLDYAVPFPVSLVISRRTIWRYQTLFRYLLSLQHLEAQLSTSWQLQSRGLPWTNRSSNRRLEVWKARAWTLRSRMLVFVQQLRYFCTTEIIEPNWQKFMARLDRSDASSTMRTVDEVIGDHIDFLDSCLKECMLTNGKLLRIHSKLMQTCAFFASPSTLTWITREIEKSDPDLLPGAARPPSISARQWSAYQATKASRPAELAQPSSSSSSTAASNQYASIDARVDNLFDLLSKWELNFSKHLQILLDALNHYAARETVVLLSLCARLSIANNGTAFSGLRHDDEAAGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG86</accession>
    <name>A0ABR3YG86_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 17">Homoaconitase, mitochondrial</fullName>
            <ecNumber evidence="5 17">4.2.1.36</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16 17">Homoaconitate hydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="primary">LYS4</name>
        <name evidence="20" type="ORF">Cpir12675_006581</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 17">Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 17">
            <text>(2R,3S)-homoisocitrate = cis-homoaconitate + H2O</text>
            <dbReference type="Rhea" id="RHEA:15485"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15404"/>
            <dbReference type="ChEBI" id="CHEBI:58174"/>
            <dbReference type="EC" id="4.2.1.36"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="17">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 17">Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-alpha-aminoadipate from 2-oxoglutarate: step 3/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 17">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 17">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.36" evidence="5 17"/>
    <dbReference type="EMBL" id="JAWDJO010000328">
        <property type="protein sequence ID" value="KAL1887348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004409">
        <property type="term" value="F:homoaconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01674">
        <property type="entry name" value="Homoaconitase_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="entry name" value="Aconitase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="entry name" value="Aconitase, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004418">
        <property type="entry name" value="Homoaconitase_mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039386">
        <property type="entry name" value="Homoaconitase_swivel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050067">
        <property type="entry name" value="IPM_dehydratase_rel_enz"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00139">
        <property type="entry name" value="h_aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43822:SF2">
        <property type="entry name" value="HOMOACONITASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43822">
        <property type="entry name" value="HOMOACONITASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="Aconitase iron-sulfur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 17" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 17" id="KW-0408">Iron</keyword>
    <keyword evidence="11 17" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="14 17 20" id="KW-0456">Lyase</keyword>
    <keyword evidence="13 17" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="8 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 17" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 17" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha" evidence="18">
        <location>
            <begin position="76"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase A/isopropylmalate dehydratase small subunit swivel" evidence="19">
        <location>
            <begin position="587"/>
            <end position="704"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00029338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00032706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU362038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAL1887348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="778" mass="83134" checksum="30A9AF2020496D72" modified="2025-10-08" version="1">MIPRASTRALALSTTRRLPTLTARSQLGSVHRNAITATTARSSFSTTAHVLNGNVLSAFDSISTPAPEDPQTLTEKIVQRYSVGLATGKKVKSGDYVTLSPHHCMTHDNSWPVALKFMSIGASTIHNNRQVVMTLDHDVQNKSENNLKKYRQIEEFAKKHGVDFYPAGRGIGHQIMVEEGYAWPGTVTVASDSHSNMYGGVGCLGTPMVRTDAASIWATGRTWWQIPPIAKITLTGIMPAGVTGKDVIVALCGLFNNDDVLNHAIEFTGSEQTLNSIPVDDRLTIANMTTEWGALSGLFPIDSVLQSWLRAKATSSAVLDEASKSKFTHEALDNLFANPLVADKGATYAKELYLNLSTLSPFVAGPNSVKVATPLRDLEAQNIAVNKAYLVSCTNSRSSDISAAARVFREAAANGQTPKIADGVKFYIAAASIPEQKAAEEAGDWQVLVNAGAETLPAGCGPCIGLGTGLLESGEVGVSASNRNFKGRMGSTAAKAYLASPEVVAASALNGKIAGPGWYEKPEGVEKVIIGEGSGDFLADKTQSVESALEKLIAEAVALAAEGEKNLAGEAADSSSAPAEGESETLTEVLEGFPEKIEGEIVWCDADNINTDGIYPGKYTYQDNVSKETMAQVCMENYDTDFRNIAKAGDILVAGFNFGCGSSREQAATAILAKKIPLVVSGSFGNIFSRNSINNALMGVEVPRLIQRLRETFKDAEKLPTRRTGWKLTWDVRRSKVTVTEGKSGESWSQKVGELPPNVQEIIARGGLEKWVKAEIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGF8</accession>
    <name>A0ABR3YGF8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mediator of RNA polymerase II transcription subunit 5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Mediator complex subunit 5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">NUT1</name>
        <name evidence="9" type="synonym">MED5</name>
        <name evidence="11" type="ORF">Cpir12675_006723</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Mediator complex subunit 5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000359">
        <property type="protein sequence ID" value="KAL1887055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014801">
        <property type="entry name" value="Mediator_Med5_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35784">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35784:SF1">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08689">
        <property type="entry name" value="Med5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0010">Activator</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1025"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1025"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1036"/>
            <end position="1062"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1887055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1110" mass="121599" checksum="CAA8045EBD317F08" modified="2025-10-08" version="1">MATVAANLPDAPAAATGAAALVPKPGPELVSTAPRRPAKGRLSRAANTILPIRRVAYLKWKHFLVQMMREGASESTLENMSRFLWKDYYIAPDPLAVLILTPRLDHYALNPRMQMYLYLALKEGYVDVPSILAAMLRFTTLSGIGQSPDTDIGSCWKSSYATDEAIFWQLAKCMSQPLDSPTGPTRRLEFAIDTLLHIVKRLAAWANLFIQVYGVLTNDVLSQVVDVNTRMEIDATHNAFVTLLLRTCEHPGIVRALAKPYATSKRSPYTAPTTHSNRPFTECRKIITHSLQLFISSCVQNPHITDRLNNFRLKISELDPCGAITEVEAEQEDSAASDLALEAVASKHIPLTNSRAALYIYLNACLVGRPVIDDDMLCNLIRNRYQHDIQNGIVDLILASFDVLANAAFQNEHKSTAQLLRSYLTNKLPLLIVTLSPGLYPTTTPEFVIQMTLNQVDPNTFPTLAAMFDDTRNNNNDFTENMRDEFCFACCLHGLIAESSIPALLGETYSTLPPGGKYSKAMLVQEAINDPERAIRLLDELDKTNGNVGAVCQALVEVFGQLCANRDTSLLKTLCSQLARQPRALDVIQLFEKPVTLLQPLCNLLDGWKYDEDQGEYQPVYEEFGSILLLVMAFAYRYNLSPPDMGIRSPDSFVAKLIREGHLSKTLAELTPTEESRLSVWTHSLFGGDTGGLTDELMASCPPQDFYLLVATLFKNMVVANSEGTLSDEALKGGIEYLVDTFLMPSLVPAVLFLADQLSVDLEQEQLAMVKILHLILQPKAIHNDTAPMLVAVMNLTAKPLERALRRYQRRYPTSQAVEPLLAAIKDCIPLSRRTGGADHNELEAWCATPSGGLAIAVRSTIHGFVQWSLNPMIGVSPTLYTHRQILVAIRRMTAQHVIRLIIDEIKAFTAHGPPAQNIAYDVALALIVSPEVTNYPEPVPHLVDDLGNIPIPIQRRLTLREVLGMKASSFREIHLIDPEKAEIVIRLHRHVEEQMAPAPAPPIIDVDIALPLAANAEVDATAQEATATGADSTVQQSSADGTASATSAQPTAGDALSDGMDLGMDMGMGDMSVMGSTGGAMDLNGDGDLFGGLGGADDFTWDSIDVIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHQ4</accession>
    <name>A0ABR3YHQ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transcription elongation factor 1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_006821</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the ELOF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000384">
        <property type="protein sequence ID" value="KAL1886954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007808">
        <property type="entry name" value="Elf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038567">
        <property type="entry name" value="T_Elf1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20934">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20934:SF0">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05129">
        <property type="entry name" value="Zn_ribbon_Elf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1886954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="109" mass="11912" checksum="878B1BB1BB901FAB" modified="2025-10-08" version="1">MGKRKSSSKPQGPKKSDPLPTTFLCLFCNHEDAVTVKINRRGGVGNLNCNICGQTFQCAINYLSAPVDVYSDWVDAADAVTSNTKTGGHFTSRPARKQQLDEIADDDDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ22</accession>
    <name>A0ABR3YJ22_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Xyloglucan-specific endo-beta-1,4-glucanase A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_006360</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 12 (cellulase H) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000287">
        <property type="protein sequence ID" value="KAL1887955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013319">
        <property type="entry name" value="GH11/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002594">
        <property type="entry name" value="GH12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34002">
        <property type="entry name" value="BLR1656 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34002:SF9">
        <property type="entry name" value="XYLOGLUCAN-SPECIFIC ENDO-BETA-1,4-GLUCANASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01670">
        <property type="entry name" value="Glyco_hydro_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="315" mass="33761" checksum="7376FA3B0CDEF388" modified="2025-10-08" version="1">MFSLRWIVNGAMMGLPVGVTLAVLFAIQPWDPSMGSGEGNRNGPWSGTDNKVITSTYCDKTVGITPPAKGMQYTFNPNQWGIDADTVGGLCLNVTANNNGTYATNSTAPLWSTTWSYTQGPDTQPVHAFPNAMIDKVLPDRLSDITTFNLIFGWTYGQGNETAETTDITSLTANSLNANVAMDLFIDSDSKKAQNSSQAGYEIMVWFAAIGAATQPIGLSQGAVATETISGITFSLYTGQNSLGQNVLSWVPTSAVEKVDTDFLPLVTKILSMTGDIYPSDTDYLGHLSIGSEAYYSDGFVTFSVSELAIDLRTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJS9</accession>
    <name>A0ABR3YJS9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006448</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000302">
        <property type="protein sequence ID" value="KAL1887689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="150"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="253" mass="28030" checksum="E99DDE187C5B775D" modified="2025-10-08" version="1">MCHGLPRLHQCSHTSLTWNYCLGAVLDLSTGYASPCAKKSIARLQPTMGKCQLKNCYFMDLGSQWTCCMCNNGPNEKGWCEAILPKYVKDPETHRTKVVETFCSHGCCANCIRGGPTIDNSDPPQGRNMPSFEGHRSKNSRHFDTEVYHRGSSAATPATSARRTGHSSYTESSYDMADDLWASQQQQQSTYSAQEGYEYCEYDEYGTDERVWSKTSPCSSRTSGTESSPSSGGSVVLDYSAKPRKSTKGKRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKR3</accession>
    <name>A0ABR3YKR3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005988</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000239">
        <property type="protein sequence ID" value="KAL1888925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="289" mass="32300" checksum="615A322FF6177342" modified="2025-10-08" version="1">MKSWLVDPNDLLEKIPESARQASPDSPLYQPASFRNLRRSPYRLRKRKRGQSDDGKSQSSRPSRRWPDDDSNDGSGSNSSGTQGGPAGGHQGPPSGSASCGAKDDSDSSSGQQEWTYSSTLHRQKKSTSGTDFSSHHPVSYQKWSQLLKKQIDEHLYHGIEDLWISGPFTGLFAVTLLGCGYKFVGKGTPKSNADRFENEAYVYHRLEPIQGTFVPVYLGQIDLCKMDRDFPHRSGHTLGFMMFLSWAGDRLNVSNKAYWSLKDGGVKSMRAIHEQGVTWRKQHCGPWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLI7</accession>
    <name>A0ABR3YLI7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Exosome 3'-&gt;5 exonuclease subunit ski4 (Csl4)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CSL4</name>
        <name evidence="5" type="ORF">Cpir12675_006085</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000251">
        <property type="protein sequence ID" value="KAL1888656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05791">
        <property type="entry name" value="S1_CSL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039771">
        <property type="entry name" value="Csl4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019495">
        <property type="entry name" value="EXOSC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025721">
        <property type="entry name" value="Exosome_cplx_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12686">
        <property type="entry name" value="3'-5' EXORIBONUCLEASE CSL4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12686:SF8">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT CSL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14382">
        <property type="entry name" value="ECR1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10447">
        <property type="entry name" value="EXOSC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110324">
        <property type="entry name" value="Ribosomal L27 protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0271">Exosome</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="4">
        <location>
            <begin position="85"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1888656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="207" mass="22733" checksum="B5DEF79F63CAFD70" modified="2025-10-08" version="1">MSAVPETAIPGTQLGPVSHYNPGPGTYLHNGNIVASVLGHVSVQQPSKSQGLVKRLTKLSVLAQPQEYPTISVFRHQRREDLLPEVGNTVLCRVTRLMPKQAIVSIQQVQASVLQTEWQGVIRSHDVRATEKDKVKIHESFKPGDVVRAQVISLGDQANYYLSTASNELGVIMATSDAGNDMVPISWKEYRDPETGISEPRKVAKPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLX0</accession>
    <name>A0ABR3YLX0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Carbonic anhydrase</fullName>
            <ecNumber evidence="2 6">4.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Carbonate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_005909</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Reversible hydration of carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>hydrogencarbonate + H(+) = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="2 6"/>
    <dbReference type="EMBL" id="JAWDJO010000229">
        <property type="protein sequence ID" value="KAL1889124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00883">
        <property type="entry name" value="beta_CA_cladeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015892">
        <property type="entry name" value="Carbonic_anhydrase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002:SF51">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="beta-carbonic anhydrase, cab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00704">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00705">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0862">Zinc</keyword>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="130"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="221" mass="25182" checksum="64B3C7B31FC0B18C" modified="2025-10-08" version="1">MADQELTKYLKASHDRIFDHNKAWAAKQAQADPSFFKNLAAGQKPEYLWISCSDSRIPAEQITGLKPGEAFIHRNIANLVCNTDLNAMSVLEYAVKHLEVKHIVVCGHYGCGGVKAAMTPKNLGILNPWLRNIRDVYRLHESELDKITDEIQRYNRLVELNVIEQCRNVIKVASVQEQYAANKFPIVHGWVFGLEDGLIKDLDVNHEKILKDIQKIYNLCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMA1</accession>
    <name>A0ABR3YMA1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ubiquitin-conjugating enzyme E2 H</fullName>
            <ecNumber evidence="7">2.3.2.23</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ubc8</name>
        <name evidence="7" type="ORF">Cpir12675_005783</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000216">
        <property type="protein sequence ID" value="KAL1889448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23797">
        <property type="entry name" value="UBCc_UBE2H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="6">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="151"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="3">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="190" mass="21339" checksum="1C6C501443109F9B" modified="2025-10-08" version="1">MSDYEVTLVNDSRYIIKSKTRKTANLIVESRSEFFVRFKGPVDTPFEGGLWKIHVELPESYPYKSPSIGFVNRIFHPNIDEISGSVCLDVINQTWSPMFDMVNIFESFLPQLLRYPNPTDPLNGEAAAMMLREPKAYDEKVKEYVAKFASKEAADETGAASDDDSDLSSVVSFSDDDDDEELAAAGQMDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNK2</accession>
    <name>A0ABR3YNK2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">3-methyl-2-oxobutanoate hydroxymethyltransferase</fullName>
            <ecNumber evidence="3 6">2.1.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ECM31</name>
        <name evidence="7" type="ORF">Cpir12675_005782</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O = 2-dehydropantoate + (6S)-5,6,7,8-tetrahydrofolate</text>
            <dbReference type="Rhea" id="RHEA:11824"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the PanB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.11" evidence="3 6"/>
    <dbReference type="EMBL" id="JAWDJO010000216">
        <property type="protein sequence ID" value="KAL1889447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003864">
        <property type="term" value="F:3-methyl-2-oxobutanoate hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06557">
        <property type="entry name" value="KPHMT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00156">
        <property type="entry name" value="PanB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003700">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00222">
        <property type="entry name" value="panB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001452">
        <property type="entry name" value="PRK00311.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20881">
        <property type="entry name" value="3-METHYL-2-OXOBUTANOATE HYDROXYMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20881:SF0">
        <property type="entry name" value="3-METHYL-2-OXOBUTANOATE HYDROXYMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02548">
        <property type="entry name" value="Pantoate_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000388">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="299" mass="31506" checksum="3332052BF1D9BFCE" modified="2025-10-08" version="1">MGDPLLMTRKKVTLNTLGRMYRKGEPIAVLTAHDFPSAHVADAAGMDIVLVGDSLAMVALGMPDTSEITLDDMILHCKSVARATSAAFTVCDLPMGSYEISPEQALASAIRLIKEGRIQAVKLEGGAEMAPTISKITRAGIPVLGHIGLTPQRQNALGGFRVQGKTVSGAQRVLQDALAVQEAGAFGMVVEAVPAEVAAIVTKKLGVPTIGIGAGNGCSGQVLVQVDMTGHFPPGRFLPKFVKQYGNVWGESIKAIERYKAEVKSREYPAAEHTYPIAKDVLESFEASALGQVVGSKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPR3</accession>
    <name>A0ABR3YPR3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2</fullName>
            <shortName evidence="8">Oligosaccharyl transferase subunit OST2</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">OST2</name>
        <name evidence="9" type="ORF">Cpir12675_005440</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the oligosaccharyltransferase (OST) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Endoplasmic reticulum membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the DAD/OST2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000186">
        <property type="protein sequence ID" value="KAL1890364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003038">
        <property type="entry name" value="DAD/Ost2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10705">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10705:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02109">
        <property type="entry name" value="DAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1890364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="155" mass="16651" checksum="B1578E10F6C58E2D" modified="2025-10-08" version="1">MAKKTANRDASLAVAATAQTPDISIAAAPVAATSKTSPSSTESKQPWNKVLGNICAHHLKTTPQRTKLLDVFMVFLVAVGAIQFLYCVLAGNYPFNAFLSGFSATVGQFVLTASLRVQTTTSNKTEFPEVSPERAFADFVGCSLILHFFCINFIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS40</accession>
    <name>A0ABR3YS40_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005204</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000169">
        <property type="protein sequence ID" value="KAL1890897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="328"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="478"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="675" mass="72658" checksum="215A632FE6D70273" modified="2025-10-08" version="1">MLKTLPFEGVSAAVLLDAEIHRRGTSTHADSTPGSSHSHNPAKFRLGCPDIDDHVLLGGIEPGSVLGISAEEDSMGLQLAMQVLAQRLVATPRQTALVASTLPVATVARTLRDVLVGMQGRKAEWRAVLARVSISRVFDFQGLWEVIGDVDAAEQAQPENGSDKEIDPGHWPSDKESGSVVKPQKDAVPEIDPLPHTQQDTPIAVQSPWAKPAKTEAPTSAVSGTDHGLNATQEPGLTALEHRKATYRPSSMEIPNSDEDDDEDDDRDMAFHFNSDLALAEQKNSDTKANAESSVSQLPESTPSTQPPPQKPHTKGLSQASKISYHTLSSSSSLSSLSSLSSLSDMEEVYEGGTDQQMGNVITSNEQTINSSRQLLKHGALDQDQFSAASSSPPRSLPTVPLPAASATDLVFDSGLHTTSPSYSLITATPTQEAPIVAIQDQIQMPRNSSTSSPPLPCPVGDSTQEPNRTRQIQARAPPAPTPTPETPPRSVPSIIVVTHFSMLLTSLFADTPSRIVAHDNLRFLSSKLRSLSRSLSSMPLIILTNSTIPSSVQPATAFGSISAHPAMRHSIAEPTLRSLFTPDPRYATEKHNRPAFGMPFSQILDLHLLCSAMPRDATDAQKMALGQAGRTAWVVEVLTDEVGVWEGKRGGRKSREQRWGAVVEKRGMFRDLRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTC6</accession>
    <name>A0ABR3YTC6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xylulose kinase</fullName>
            <ecNumber evidence="7">2.7.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_005082</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">Highly specific D-xylulose kinase which participates in the catabolism of xylose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>D-xylulose + ATP = D-xylulose 5-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10964"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17140"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.17"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the FGGY kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.17" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000161">
        <property type="protein sequence ID" value="KAL1891146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07776">
        <property type="entry name" value="ASKHA_NBD_FGGY_SpXK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042024">
        <property type="entry name" value="D-XK_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="FGGY_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10196">
        <property type="entry name" value="SUGAR KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10196:SF57">
        <property type="entry name" value="XYLULOSE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 7" id="KW-0859">Xylose metabolism</keyword>
    <feature type="domain" description="Carbohydrate kinase FGGY N-terminal" evidence="8">
        <location>
            <begin position="132"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate kinase FGGY C-terminal" evidence="9">
        <location>
            <begin position="302"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="574" mass="62304" checksum="11E93D4DC95A1BA5" modified="2025-10-08" version="1">MAHYLGLDLSTQQLKAIVVSSDLIVVSEAKVDFDADFGSQYGITKGVHINQNDNSVYAPVAMWLEALDLVLARLSAKTDMAAIKGISGSCQQHGSVYWSLSAEEKLKGLTAESSRGLKEQLGMAFSHPWAPNWQDGSTQRECDQFDAEFGSPAKLAEITGSAAHHRFTGPQIMRLKRLFPDMYSNTSRISLVSSFLASLLLGHIAPIDISDACGMNLWDISANDWSPALLHLTTQASSDPAAAADLRAKLGSVRRDGGGSMGSLSPYFVIKYGMSLDCQIAPFTGDNPATILALPLRPMDAIISLGTSTTFLMSTPYYKPDPAYHFFNHPTTPGQYMFMLCYKNGGLAREKVRDMLPSAADKDGDAWASFNSKVTGTSPLHMGNEEDKAKLGLYFYLNEIVPNIRAGTWRFECGPSGDNLTQLPAGKAWDPELDARVIVESQALSMKLRSKNLVHSPADQPSFPPQPRRIYLVGGGSLNPAISKVIGDVLGGLEGVYRLDVGGNACALGGAYKAVWALERAEGETFDELIGKRWKEEAAIEKASDGYDEKVFAKYEKVLGAFEQMETKLLAEGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU38</accession>
    <name>A0ABR3YU38_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004972</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000155">
        <property type="protein sequence ID" value="KAL1891358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="514" mass="55816" checksum="572C2864C8FDC1F2" modified="2025-10-08" version="1">MGWGNIVEKQESLGQLIDVLEATRTVKESKMSQSTPPASEAAHPSSPVNEDSLPERPSAPIPPGSSSIYGQSPSPCAQRKLRNKRSSLNFDPAEFSFMTGGTRLSYDGATTTRPHTIVAESDWITEPDSVPDPALRSTCLLQAGQRQSLRPILPVRPHCLAPSITTGSDSRCSTYTPMAGTMLAKSLSGDATSNCDLNSSLAATVATGSVPPVPKIPDDSELRARLASVQANLHLVSPGMLHKRLYNQRELTTPNSLNHVQSNTIRMIKPDMGISSSLYPFERERHKLTHPSLVPDDLCIIKNEYLQQANTEQPGSKLRQQHNRSSSAMQSSPLLPPLMQHQAVSINADESLASGNVSSGTVVIRVPITKYEESSSAILPSSPPSAFLGNNLHLQRSRRPDPIDIPGTNGFLVPGMQAGRSPMMSPMDYASASLGLEPFSPVDRGGEEMGAQDRLKRVSSTGRNARVVDWLLSVRDKASRSLINRNSMHQYQQQPKLEGEFDSLLRCGKTLLTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUJ1</accession>
    <name>A0ABR3YUJ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Erythromycin biosynthesis protein CIII-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_004840</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000147">
        <property type="protein sequence ID" value="KAL1891767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF13">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Erythromycin biosynthesis protein CIII-like C-terminal" evidence="3">
        <location>
            <begin position="171"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="377"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="675"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="742"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="388"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="436"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="457"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="678"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="742"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="777"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="787"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="829"/>
            <end position="839"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="845" mass="91101" checksum="A871DE9AC01FBDC4" modified="2025-10-08" version="1">MPWSPTRAFPHPLVNMQASSSMDNATANTVTYGLVEMFTWQGLADIINKFRVDVLELEALTVAWTPGILHRLQIPFTYCWSPALIPKPQDWGNHIDVSGFFMLDLASNYSPDQDLDAFLKAGPPPVYIGFGSIVVNDPDALTRLIFEAVRMAGVRALVSKGWGGLGGESLQVPDNIFMLGNCPHDWLFKHVSAVVHHGGAGTSSAGIHAGVPTAIVPFFGDQPFWGSMIARAGAGPDPIPFAKITALKLAEALKVCGRPDVKLKAKELGAKICQENGTMQGAQSFHKQLDIGDLRCSLLPHRTAVWKVKRSGVKLCAMAAALLVRNGLLSWSDLKIYRSQEHNTVAEPWEPVSGFTANVVNDIAKVAYALADFHSGVSSPKKPAVAGSVSSKSETSSIISKRDLGYPSGESAHSKPGSDRYTPMLTHRATEPPPNSQSVAGPSSIKQMPSIPTLQPSDRSSTNMTTSSTSTISTVSRDSGKMVSKTKEVGREAGKGVAKLIELGAMTPINMSIGMAKGFRNAPKLYNDPMIRESEKVKGIASGFKVAGKEFGYGIYDGVTGLVMQPYIGAQTGGKKGMVKGIAKGLGGFLLKPIGAFWALPAYGFQGAYMQLKGMGKKTYQAYIEASRVAQGEEDLQGISPADEKDILEGWKSIETGEGKKKSFWAASALSLARPMTSGSSTPSYSSQRRAEEPPMPSFPSERQSSRASTYDRLDDQRLGVHGSQPPASIAEDVGDAASVNSSRYMQHQSTGQSHQSYTYSDRGSIHSATGPAGSVVSRSSTWRSEQPQFPSQAQAQALPIRQQQDHIPQEPQELESPTNLPEYQTSRTQEEQREREGEENTQPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUK7</accession>
    <name>A0ABR3YUK7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peroxidase</fullName>
            <ecNumber evidence="7">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_004879</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the peroxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000149">
        <property type="protein sequence ID" value="KAL1891659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF66">
        <property type="entry name" value="CATALASE-PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 7" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045009291" description="Peroxidase" evidence="7">
        <location>
            <begin position="20"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="9">
        <location>
            <begin position="144"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="359"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="365"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="379"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="421"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="445" mass="48163" checksum="2D662D4789126DC0" modified="2025-10-08" version="1">MHFTRVLSLALAVAQPGLTHPGMKKVLSEIREISKRSTMPTDSTELIGDLATLSDGELTATGALIKSIILNQADPESYEDNTASADISSPECKEDTCCIWSHIADEMHALFTSPSGRCTKWARFAIRLGFHDAGSWNKSSTNGGADGSIVLAAEERARGENGGLVAMIEQTQAWYTKYHDELGYDSVTMADLIQLGANVATVTCPLGPRVRTFIGRKDSSLPAPTNLLPSPFASAELLIQLFAEKTIGSRGLVALVGAHTTSQQTTVDPQRALDPQDSTPGVWDTLYYRQTLSQNPPPRLFRFQSDLNLAAHDQTSGDFRAFGGRNGQALWNRDYAREYVRLSLLGVNNINDLQECTKVLPQPTRGNGRSRPGSGNSPAASTLPKSDATDSNFGLDSISSPSNLEWTPPDQNQIDKWLQTVGRSGSNKNVGQMLAAGQTVTKLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUL3</accession>
    <name>A0ABR3YUL3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YMC020W-like alpha/beta hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004747</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000141">
        <property type="protein sequence ID" value="KAL1892021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058934">
        <property type="entry name" value="YMC020W-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058933">
        <property type="entry name" value="YMC020W-like_ab_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47349:SF1">
        <property type="entry name" value="AER328WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47349">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26147">
        <property type="entry name" value="AB_HYDROLASE_YMC0-YMC35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YMC020W-like alpha/beta hydrolase" evidence="2">
        <location>
            <begin position="542"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="462"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="329"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="479"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="942" mass="101353" checksum="96D515D12D4A9DFC" modified="2025-10-08" version="1">MVKAQAPPTTQPRAAPKPIESQNPPTNTKDSGESSKTSNNSSMTAPGPVDTLPRRVAKRPSWYGSWPRKSATSTKVVCETIRGDTFQPLESSSSANLTRLDAVIKRAASIQSINVTETHTETHTDSRLLQQQLQQNNSRPSSLQEQPDPPLSASSISTREQNPQMTATASQTTTIETQTPLPLAPPLAETDPELAIVPASSTSQQGTAKKTSTNLPFQNVESPEAVQLEEPREEPPGDLPQPPSGWLSWLVRPAAPIETPKMTGAHEPTQETLGHAVPTQDPEPASHEPQTEDSYNSPPSPQSKPNAPVSYNSSSWLGYWYGGFRAAAAEDSSNEASGSTQNPAPETSQQENQQESRLEPQEDTPMSGAALSNDTSQSLVTGFQEPSKPSTSVTWAFWSRQPRASGTHQATVQPQQGELAVMGEASEASPTPALEVDAPTKPKNKTTKQSFALGAAAEALPLPMLPSEDKKQRHGGLGDSLSASFSSSPSKSTVTTGPTGRSLKSQSESNLRRQDGLVGSLDSTSSDTAAPCEATANPNLLLPSFNSTYSIKEPPSLISQITNLILRSHKHPPTKHVFRSINPPARPVLKAISIGVHGLFPAAYLRPMVGQPTGTSLRFATLGAEAIARWTAAHGFADCYIEKVALEGEGKIAERVESLWKLLLNWLDQLKEADLILISCHSQGVPVGIMLLARLLDLGVITSTTHISVCAMAGVCLGPFPDYKSSMGMLMGSAGELWEFSNPESDISQRLEAALRSVLQFGARITFVGSIDDQLVPLESAVYSPAQHPHIYRAVFIDGRLHAPDFIAHLVGFALKLRNLGISDHGLIRELSVPLAGSLYSGEGHSRLYYDARVYDLALANALETTSVEPGTSCSIGPRGSLAPTNPYTLPWVMRGLLEEDLVKTSLAEETRVLLQQFQAWNPTTKALKDVKYRLDAVRSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUW5</accession>
    <name>A0ABR3YUW5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_004820</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000146">
        <property type="protein sequence ID" value="KAL1891779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018466">
        <property type="entry name" value="Kre9/Knh1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052982">
        <property type="entry name" value="SRP1/TIP1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40633:SF1">
        <property type="entry name" value="GPI ANCHORED SERINE-THREONINE RICH PROTEIN (AFU_ORTHOLOGUE AFUA_1G03630)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40633">
        <property type="entry name" value="MATRIX PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05410)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10342">
        <property type="entry name" value="Kre9_KNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047404608" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein" evidence="4">
        <location>
            <begin position="23"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal" evidence="5">
        <location>
            <begin position="29"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="124"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="124"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="165"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="198"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="232"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="273" mass="28012" checksum="C7661BB86DD03478" modified="2025-10-08" version="1">MQYSMFALIAALAGNAIAQIDGFNPITAPTRDEVLTAGSNCVIQWSPDATYNADTITIQLMAGTSNTTLDVTDAVASSISSSAGKYDWVIPSTLKQANTYGFKLVLDKDNSIFQYSNPFSIKFGTGSSSTSEEATYGEPKTSATTAPATTTTEEPVYGEKHSEETSSSSPSSTSVPSYGEHESSSTSIPSYGEHKSSTTETTEPSVPTTPSYNNTEPEVPTEAAPTTLVPVGTGTAAPSGTGAINPTMTPITAGAGVVGAPLALLAGVVALLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUY3</accession>
    <name>A0ABR3YUY3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UspA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004776</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000143">
        <property type="protein sequence ID" value="KAL1891917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23659">
        <property type="entry name" value="USP_At3g01520-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47815">
        <property type="entry name" value="UNIVERSAL STRESS PROTEIN A FAMILY PROTEIN C25B2.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47815:SF1">
        <property type="entry name" value="UNIVERSAL STRESS PROTEIN A FAMILY PROTEIN C25B2.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UspA" evidence="2">
        <location>
            <begin position="45"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="265"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="362" mass="40081" checksum="63438EA2CA4F6E88" modified="2025-10-08" version="1">MRSAPRFQSHVAFGNLDSVETTKNNTIGITLQTRHKAYRLHKLSRTFMVGLDDHEYSHDALSWLLDSMIEDGDIVVCVKVNEKDVKPSSEMSYQKEARELLAWTESQNVHNKGIHMVLEYSFGKLTQTFRGLIEVHQPGMLVVGTKGKAAQGIQGVWNSRNSFSKYCLQYSPVPVVVVRPKDKRIKKKEKRSNDVTRRGYRGMLESMGGVHEIDMDLDEMEKLMETSNTADEEAHHVARALGLPASFDPLIKGIDPNVVLRGRTSAANSRPSSSSGASLPSSLSNVSLKASQSSNPESGPGQSRMSIVHTQTSEDDESDGVDSEMDVPRPASASIQNREKLHRMEVGEAAALKKTAWSDDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV80</accession>
    <name>A0ABR3YV80_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">mRNA 3' end processing factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PCF11_1</name>
        <name evidence="4" type="ORF">Cpir12675_004604</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000134">
        <property type="protein sequence ID" value="KAL1892281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045154">
        <property type="entry name" value="PCF11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054127">
        <property type="entry name" value="Pcf11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021605">
        <property type="entry name" value="Pcf11_Clp1-ID"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15921:SF3">
        <property type="entry name" value="PRE-MRNA CLEAVAGE COMPLEX 2 PROTEIN PCF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15921">
        <property type="entry name" value="PRE-MRNA CLEAVAGE COMPLEX II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21936">
        <property type="entry name" value="Pcf11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11526">
        <property type="entry name" value="Pfc11_Clp1_ID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pcf11 Clp1-ID" evidence="2">
        <location>
            <begin position="36"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Pcf11 C-terminal" evidence="3">
        <location>
            <begin position="88"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="175" mass="20328" checksum="BE91D2B10D52AE3A" modified="2025-10-08" version="1">MLEGLGKPCSQCGRRFKNDEDGRKKRVRHMDWHFQVHQRSVKAEKHGQHRSWYPDTKDWTVSRETIDADIPEVTSTTNSAPKQPEVQYILVPDPTEVVNTACSICADKFINKWLDSAQEWVWLDTMRVGNKAYHASCYNEAFRSRNTPEPVLGKRKAESPNHFMVEGKKWRAEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW81</accession>
    <name>A0ABR3YW81_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004659</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000137">
        <property type="protein sequence ID" value="KAL1892151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="370" mass="40230" checksum="EB474898DB640C6E" modified="2025-10-08" version="1">MRAVLRASRPGSCPNTKPLVARPIRLQTRAFVAVPALNASSLKSLRHVSSGSRQAPPSGRLKRTTGDRPSPLVQVIPQVRAVVTADRQIPDLNSFVRAAEATGLSENRTKVYRDCVISIIAAFKTSTDDWNWIRGWASKNKLTPKLIYESAITYHTATPREDASPAVATTTLMLLYAAGVHMNYVPALLSFAHLTILSGSHPSTMNIFSEAHAAFARLLRTGDPDALTIEAKYKLGSMSNGEEAQRLLARALKTGGAFEWRPMALVLLARVHIEDGDVARARQLLGQAISESDYSIAHDELAELDKSGSKEGLDMSPQETVTAALNGRPTGLRSLARMFMGASVGDTSEAETAFYSKAMENMRFARDRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW94</accession>
    <name>A0ABR3YW94_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000136">
        <property type="protein sequence ID" value="KAL1892177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="90" mass="9867" checksum="DB055FFA6861DBEC" modified="2025-10-08" version="1">MSPALFAAARTSARVASSRQFSLLTSMRNVARSFEPHPFQRLPVSHASARPDYSALMKRIGGQTMVFVPAFGTIMAWPLVASQFLDGHVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX48</accession>
    <name>A0ABR3YX48_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">General alpha-glucoside permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_004793</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000144">
        <property type="protein sequence ID" value="KAL1891904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432:SF35">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 45 MEMBER 3 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432">
        <property type="entry name" value="SUGAR TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13347">
        <property type="entry name" value="MFS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="389"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="447"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="471"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="560"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="590"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="652"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="31"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="50"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1891904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="683" mass="73940" checksum="F68695F126649A31" modified="2025-10-08" version="1">MVSSRSSSDGHSPPTPIRPKFIDPDVDPLNEESPLLSPASPNPSHGARSTDFTFPPTGNASSAAHHPNYASSSPISSPSRDERNTKSVWYLILLTISIGGLQIAWSVELSNGSPYLLSLGLSKSLMALVWIAGPLSGTLVQPYVGMLSDNCRLPWGKRKPFMLGGTIATVASLLFLAWTKEIVMAVLGVLGFDTDGSGAKNTVIVVAVIGVYVLDFAINTVQAAIRAFIVDCAPSHQQEAANAMASRITGVGNIVGYLAGYVELQRYVPWLGSTQFQGLCAIASIFLASTVCLSIAVIPERDPRLDGKPPKARPGLISFFIGLFHSIRRLPAQIKRVCLVQLFSWIGWFPFLFYTSSYIGELYVEPFLEENPNMSDQELEKLYGEATRIGTLALFVNSIVTLLTNVFLPFFIAPTYDKAPMGDDSCESKPMSALDRLRIRGFTLKQAWFISLVFFALTLLATVFVHSVKVATVLVGSIGFTWALTLWAPWAIISAEISRRDALIRERKLKQQELASQWFPFRTPQGLGNFDNTHSPELGLDEAAEHDEAGVILGIHNMSIAAPQIIANITSSVIFSIWQKPRGTPGDRSMTYVFALGSIFVLIAAAFVFRINDGALEERANNDLDFGSEGHRLLSSDAPFGIDDFEQDTGLVSARSSAEGSKKGSSDGGGSAGMSFQSTPNVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXT6</accession>
    <name>A0ABR3YXT6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein-ribulosamine 3-kinase</fullName>
            <ecNumber evidence="1">2.7.1.172</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_004420</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>N(6)-D-ribulosyl-L-lysyl-[protein] + ATP = N(6)-(3-O-phospho-D-ribulosyl)-L-lysyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48432"/>
            <dbReference type="Rhea" id="RHEA-COMP:12103"/>
            <dbReference type="Rhea" id="RHEA-COMP:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:90418"/>
            <dbReference type="ChEBI" id="CHEBI:90420"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.172"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:48433"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fructosamine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.172" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000124">
        <property type="protein sequence ID" value="KAL1892721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016477">
        <property type="entry name" value="Fructo-/Ketosamine-3-kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149">
        <property type="entry name" value="FRUCTOSAMINE 3 KINASE-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149:SF8">
        <property type="entry name" value="PROTEIN-RIBULOSAMINE 3-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03881">
        <property type="entry name" value="Fructosamin_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006221">
        <property type="entry name" value="Ketosamine-3-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00048655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR006221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="321" mass="35977" checksum="4D304FA0CD2EB5F8" modified="2025-10-08" version="1">MAPEAVDPAILESLGLEDSVSTLSRFGSSAFATSYRLDTKINGEPMVYFVKSASGPEAEVMFQGEHESLNSIARIVPNFCPRSLAYGRLRHYPGFFIATDFLHPSSDTPSTGATLAVKLATLHTTPAPIPYGARTPMYGFHVTTCCGCTEQENTWKSTWGEFFAECRLRAIMRNIQRSHGNEEELMYGVEAVAETVVPRLLGEQTLQGIYPVVVHGDLWSGNYSQGILHGQEEEVVYDAACVYGHSEYDLGIMKMFGGFGMDFWQEYQQLVPPHEPQEEFNDRLQLYELYHYLNHYAMYGGGYKSSAFNILRDLLNKYAPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXZ1</accession>
    <name>A0ABR3YXZ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004249</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000116">
        <property type="protein sequence ID" value="KAL1893103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="277" mass="30680" checksum="37948D54D5E12580" modified="2025-10-08" version="1">MAPGAIRCTHVSLTIARLGSNAPQHASLSLLSRPFFQAAFKSPSRPSTARLFSQIHALRSSGMPRVDSQEALTTKHAKFLFPARIPIYHVGTGRFIFIAVLKLTTIVMCALFCGIAVPSYVAAEKDNSQTIGLGLCGMIPLLTVIYITSPYVAFLHIHLPPAARLSRDTLRRYVLNMPPTAQIDITTLSVIAKPRTATIEARALRVANPPRRLGLVNFVRTPEDISRENAGRKWWRFRAVGSLNITGSNRGVKEGWIWDELRKRLERVSANEQRSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYX6</accession>
    <name>A0ABR3YYX6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein-lysine N-methyltransferase EFM4</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Elongation factor methyltransferase 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">EFM4</name>
        <name evidence="8" type="ORF">Cpir12675_004241</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000115">
        <property type="protein sequence ID" value="KAL1893222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03188">
        <property type="entry name" value="Methyltr_EFM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026635">
        <property type="entry name" value="Efm4/METTL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12843:SF5">
        <property type="entry name" value="EEF1A LYSINE METHYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12843">
        <property type="entry name" value="PROTEIN-LYSINE N-METHYLTRANSFERASE METTL10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Methyltransferase" evidence="7">
        <location>
            <begin position="121"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="72"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="315" mass="34263" checksum="69EAE9DB07ED7FBE" modified="2025-10-08" version="1">MVTSKGSSKPAHLEPSKLGTREYWDSLYVGEKSNHEANPRDKGTVWFDDSNAESKVLRFLCARAIDEPVPESFPAGCGSGSASDSDSDSDSDSTDHDSESENEDEDATNSPHKDLSYRTSSILDLGCGNGSLIFALRRRGFAGSRLGIDYSMASIDFATQIAAAAGTPDDALAFSQWDVLKGAFSDVLGDINGSRLKFAHTATGFDVVLDKGTFDAISLSDETGVHGRRVCEDYARRVLHLVRRGGILVITSCNWTEAELISWFEKPVSEENSSVSGREEDDVGRWVLDGRIKYRAFSFGGVTGQTISTLCFRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZU1</accession>
    <name>A0ABR3YZU1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dienelactone hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003877</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000099">
        <property type="protein sequence ID" value="KAL1893901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47562">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47562:SF2">
        <property type="entry name" value="CARBOXYMETHYLENEBUTENOLIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="35"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="283" mass="30978" checksum="5D5CC2BD882CE218" modified="2025-10-08" version="1">MLIKETHVDVQTAVDGKESTMRIFVFHPTIPQFPNAKFPGVVLFSEIYQVTGPVARFARQIAGQGYIVAAPSSYHEFTGPAPLAYDVAGTDAGNAWKVAKTLASYDEDVLRTVNHLLSLPTCTGRIGATGMCLGGHLALRACLDTRITACVSYFATDVHCRTLGPHDAANTSADSPQGSNHTIDRLAEMRAEVAMIFGVKDTHVPAEGRDLIRAKLRGANVTTSFYEFAWAQHAFIRDELSKGRYDPAITKVCFEVLLELFGRMLKTDLGEMDDRSVEIEHVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZW3</accession>
    <name>A0ABR3YZW3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Plasma membrane calcium</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">PMC1_2</name>
        <name evidence="1" type="ORF">Cpir12675_004075</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000108">
        <property type="protein sequence ID" value="KAL1893467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1893467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="253" mass="28039" checksum="14A2E9C2512CD291" modified="2025-10-08" version="1">MPSLEQTAIAPENKVVSAANLSPSHKFEVNLHDALTPDPGIKDMFHRTSRFFPYTPGGLSKILNPKTLNGFLALGGLIGPEKGLDTNRKVGLDPEEFHILVEISFGKVVVVVPGASERIPELMWIVHKDKILILLTWNALISPALDLYETLDLLTPRLDGLKVVRAGKSAEMSGWDTMVRDVMHLEPEYLISVDGIFIDGHGIKYDEPFAIGESGLLHKIPADEVFGCLKAAAEGQTKIRNTEKTWLIHYFRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0U8</accession>
    <name>A0ABR3Z0U8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_003953</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000102">
        <property type="protein sequence ID" value="KAL1893834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF42">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="97"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="236"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="40"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="270"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="271"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="363" mass="39674" checksum="E6CD4BE330205F00" modified="2025-10-08" version="1">MSAFVQGSSAAWKPPSDNLSDRMRVVSWIMLSLSTVFVALRVYCKTLNARGLWWDDYILLLAYVIFVANVCMTEFNARIGMGTHIYYIDVTHLSRLALLGNISGFISIFASIFSKISFAVTLLRITKGVWRGIVWTCIAITVMSMSISAVFIWVDAGSHASVDYGIFSAALSGLIDLLLAMLPWKIIWGLQMRTKEKIGVGAAMSMGMFACVTACVKASKVPSLGSGDFTYHGAELVIWAAAEVGTSMMAASIPVLRVLITRIKTTYLNSGEKRSHPHSDRSNDSGGSKGGTLSGSGRRSRIFDLDEDILVTKMRSGTAMSDTTCPDIQRPSTSRTMTIGYNDDHDLQHLDEGLELSKIDHVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0V0</accession>
    <name>A0ABR3Z0V0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003968</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000103">
        <property type="protein sequence ID" value="KAL1893812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="199"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="154"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="253"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="339"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="450"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="261"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="271"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="344"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="365"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="493" mass="52670" checksum="950657E8853F4DEC" modified="2025-10-08" version="1">MSVTTTMPTSTPTFASVFVPASVPASASGLAPAPAHITGLLLRPAHTRTPSHTYTPLAISPMNSNNRINRRKSVSSVSHNTVAAVASALEASPLALPGPSSKRYTATAPMPLSSSMGCINSGSSTSPPSAQNFVTSVPAVKKESIELGEYRMSQTPLSHGSLSPPAPDTSLEEQSRLRRASDGQPLVREGGKRFNRVELRCETCGKSYKHSSCLTKHLWEHTPEWSYTSKLLISKHQQVQLLEAASVLVAMNHNDPKSDSTSESPSDSTSGFHSESDSVSTADSVLNRHERTSSTETTPPPMEGLGLKLNSHQFSAKRYSTGGISKAYKLGNYKPSTSILQGISSSGPNGSSSNHGRKRSEDIRPTSSGRSSTGKVDRELAAAVELLSCSFSSNNAKSPSTTTLVPLVPALPIQYLEQSTSFASSGFLSSFPSRQPESFTRGESFIRGSKSLRSDVDMNDSSNESVLGDFDDDDVRRARNDEDDDGVFGHMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0Z2</accession>
    <name>A0ABR3Z0Z2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nuclear pore complex subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">NIC96_1</name>
        <name evidence="7" type="ORF">Cpir12675_003723</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FGGY kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000093">
        <property type="protein sequence ID" value="KAL1894295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07782">
        <property type="entry name" value="ASKHA_NBD_FGGY_D-RBK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="FGGY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006003">
        <property type="entry name" value="FGGY_RbtK-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01315">
        <property type="entry name" value="5C_CHO_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43435:SF4">
        <property type="entry name" value="FGGY CARBOHYDRATE KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43435">
        <property type="entry name" value="RIBULOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase FGGY N-terminal" evidence="5">
        <location>
            <begin position="770"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate kinase FGGY C-terminal" evidence="6">
        <location>
            <begin position="1072"/>
            <end position="1282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="49"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="79"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1894295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1353" mass="151986" checksum="85AC8BC7CADD9E80" modified="2025-10-08" version="1">MTEREDRRGRGFWGLLRSVSLTRKMTKSVKDNRRASSTDVSSSRHASTTRHEGYQDGPRRRSYHPEPFNPSQSRTSRAKNKEKAHGLRDSSSRQPRWPPSGVSKDEALSERRANSLIARGASTHRGFKKSIPNADKTFYRCYSASSCKNNSLTGRANNQKIMADMQTMVLQGVDPESRWSPWETVEQPSYTFHHGHLPGTITLNQWAWSASVVPEAIRHRKSSIELRDVDLVDIFRRIHELQDCTVFDVDDEDVMYKHFLRDPEPKMRFHGPNATRPLERQVTDLIHVLSRNDWIDFSQRKNQLVTQFIASNSPDKEEDIHKFYHQLVLTLELLFRLTHRRFPADQRKRMTTEIPPMIQWSLALARRWKEGVRIDSFSHYLDDLILSFPNKKTQMRCLRRFARELKWPNLRETLDEMRDLEMEGALTDLSEDSMAFFSGLILPGDSFPYIVMNALTDIDPDPASNKLEHLLLDYPDCGFQYRNSYTYWPVTCIVGKVLAPTCNTIGGWVGPARPTNDLERTQLARLLVNRPKRRIHAQDVEDMRYGSSPLGPETDDYAVEEYILPLPNQEEIVDTVRIEQITLEKQVHPIKKNGVDDGGHSDHRDNDAVISATGSNNAENAPQLYQALVIFAIDGTSWPLKLQFDVSFVAAWPCSDSPHPLWTGYAFERVAVDKIVRVHNWGNVYRGSQQYQAASVVNDDGDDMKVLLIESFGVRDNEVLARAWCAHWGLSAVVADIASTCIPCAIREAYAAAITVVIMIDSQFYTAKKYIGIDVGTGSARACLINEDGAILSSFSEEIRMWKPQPGYYEQSTTDIWKAICSCVKHIMAKTQTDPSDIKGIGFDATCSLAVFTHDTDEPVSVTGPDFKRDADERNVILWLDHRPKQETKTINSTNHPLLKYVGGRMSIEMEIPKVLWLKSNMPPELFKRSKFYDLADALTHIATGLETRSFCSAVCKQGYVPVGVDGSVKGWQDDFYKTIGLEELTHDDYLRVGGVHGKNGIFMSAGELVGRLCEKAAKSLGLLPGVAIGSGVIDAYAGWIGTVGAPLEVPLTGVEAEERGADDLTTAFTRLAAVAGTSTCHLAMSKKPIFVDGVWGPYRDVVIPGYWMAEGGQSATGELLKHMIEIHPAYSEAKEMAGEINIYDFLNAWLDHLEDEGGAPSVSYLARHIFFYGDLWGNRSPIADSTMRGAYVGMNSDKSIDNLALQYYAAMEFIAMQTRQIITTMNKSGHQIYSIFMSGSQCLNPKLMSLLATVCGVPVVIPEYANSAVVHGAAMLGAKAASANEKGETESLWSIMKRMSRPARVVKPDDDEGQKLLLDAKYAIFLDLAYRQQSYRNQVDASVEVWLTEYGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z118</accession>
    <name>A0ABR3Z118_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">threonine synthase</fullName>
            <ecNumber evidence="4">4.2.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">THR4</name>
        <name evidence="12" type="ORF">Cpir12675_003736</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the threonine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.1" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000093">
        <property type="protein sequence ID" value="KAL1894308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004795">
        <property type="term" value="F:threonine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01560">
        <property type="entry name" value="Thr-synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1380.10">
        <property type="entry name" value="Threonine synthase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029144">
        <property type="entry name" value="Thr_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037158">
        <property type="entry name" value="Thr_synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004450">
        <property type="entry name" value="Thr_synthase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051166">
        <property type="entry name" value="Threonine_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00260">
        <property type="entry name" value="thrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42690">
        <property type="entry name" value="THREONINE SYNTHASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42690:SF1">
        <property type="entry name" value="THREONINE SYNTHASE-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24857">
        <property type="entry name" value="THR4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14821">
        <property type="entry name" value="Thr_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Threonine synthase N-terminal" evidence="11">
        <location>
            <begin position="13"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="10">
        <location>
            <begin position="98"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="324"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1894308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="535" mass="58961" checksum="23EFF03FD26BC544" modified="2025-10-08" version="1">MAANGSTHTRSQRYLSTRGEDTDLSFEEVVLKGLATDGGLYIPETIPTATNWESWKDLSFSDLAYEILSLYISSSEIPAADLKGIINRSYNTFRHPDTTPLVHLKGNLHLLELFHGPTFAFKDVALQFLGNLFEYFLVRRNEGKTGADRHHLTVVGATSGDTGSAAIYGLRGKKDVSVFILHPKGRVSPIQEAQMTTVLDANVHNLAVAGTFDDCQDTVKALFNDPEINATLNLGAVNSINWARILAQIVYYFHSYFALAKQSDTFKLGNKVRYVVPTGNFGDILAGYFAFRMGLPVEKLVIATNENDILDRFWKTGRCEKQDSSPSAASSEAKQDSSGVKETLSPAMDILVSSNFERLMYFLAYEYAAAAGMDEEWNRKQAGQEVSKWLSDLKTKGGFGPVYDDLLGFARRDFTSERVNDAQTSATIKSMYDAVGYVLDPHTAVGVTVAEHSLADAKDVPHISLSTAHPAKFAGAVEDALKNAENFDFATKVLPQEFIGLETREKRVTDVENSWTVVRDIVRKQVTEELASASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z137</accession>
    <name>A0ABR3Z137_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">HTZ1</name>
        <name evidence="8" type="ORF">Cpir12675_003878</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the histone H2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000099">
        <property type="protein sequence ID" value="KAL1893902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="6">
        <location>
            <begin position="17"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="7">
        <location>
            <begin position="103"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="142" mass="15035" checksum="6C4A38DAC9DAD3C5" modified="2025-10-08" version="1">MAGGKGKSGGKSSGGKTSADGPKKQQSASARAGLQFPCGRVKRYLKQNTQNKVRVGAKAAVYVTAVLEYLTAEVLELAGNAAKDLKVKRISPRHLQLAIRGDEELDTLIRATIAYGGVLPHINRALLLKVEQKKKKAAQAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1P9</accession>
    <name>A0ABR3Z1P9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Zinc transporter ZIP9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_003815</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000096">
        <property type="protein sequence ID" value="KAL1894127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045891">
        <property type="entry name" value="ZIP9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16133">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER , MEMBER 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16133:SF0">
        <property type="entry name" value="ZINC_IRON REGULATED TRANSPORTER-RELATED PROTEIN 102B, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="222"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="318"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="321"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="368" mass="38777" checksum="9B2F5B439B01ECCF" modified="2025-10-08" version="1">MTLSQSQLRLITSIGVGILIGTSMTVIIPEGIEALTLHAHSHSHSSVDPLPETNPGHRRSFGGQSSVESGALPELQVSAPIAPVQRDILAAISETLERREANDDHNPGSDSELPTFSIGFSLISGFLLMFFIDRLPRHATDHLSVQASRDISLDNLGSADGVSGSLLDQETAGFSSSLGLTRVGSPYSASSRSNSLTVGLVIHAAADGIAMGASSSTENTKLGFIIFLAILVHKAPAAFGLTTVLLRQGVSKYAARGHLLVFSVAAPCGALGTWLLIHLLGGGRGMQGTEGHYWTGMLLLFSAGTFLYVAMHAMQEETSPHESGSATTNSYPESPHQRKRAGFQMRDTLATAGGMLLPLLTQTGHHSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1X3</accession>
    <name>A0ABR3Z1X3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">STB6-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003844</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000098">
        <property type="protein sequence ID" value="KAL1894060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038919">
        <property type="entry name" value="STB2/STB2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059025">
        <property type="entry name" value="STB6_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31011">
        <property type="entry name" value="PROTEIN STB2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31011:SF2">
        <property type="entry name" value="PROTEIN STB2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25995">
        <property type="entry name" value="STB6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STB6-like N-terminal" evidence="3">
        <location>
            <begin position="14"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="491"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="770"/>
            <end position="797"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="829" mass="92254" checksum="9ED5EFC2E1C39B7F" modified="2025-10-08" version="1">MAQRVTEAASVPQKRLVIPDPVALRYLGEDPLVHIVESRTTLEGYELYLVEQWACSRKSASTVIASYTGDAKSTIVVGVISVPEDQTFWSLRLKMFFREVQQHHARPRDTPLGDLITTNLSSFPSALTTILVPNGDIKSYQKMFIVNENLKRLGCSGRAGLTLDEPAPAAQAKFCSMYRVHEQINFLEAAIELVRLCQMALIVFGQLNTIFSDGLLCDMTEAAISNWWTDIGVEYYNMEPSDGILGPMTVSALLGLLMGARNRLNSYGAAVSKDAFEIESTMRGVSHFQKYQKMERTGVLDRETLLKLQSATAKAAANEGWAVQRAVKSTVAEIGGKRGELVMGIVSGRDKGGISEVETLDIEKFVGYAYGELPKWLWQGKTRRSTAESSHEKHTEIGSALMAAKEQQEILSMATQRASSIPVSEYADSNNGKEDLYGVPPQSTMSGTFLTSTISQDSPIDKGEKKTRFKSVTERMSDARSGLGRIKDAVGGSRRVAKSGRDDCSDVPSSPMAYHATGTNGPFKTSAWNKTPEFYAAHSHREKDLERMTSHMPIHIGAEATPDKALSAGFSESLPGDSSDAKDSKDPMFIATSLTGINDARDHWLAEDEPVNLCMQRLQRRYSFHSTQERPAYNDARWSRRASFSDAADAVLRWEEIVPMFDVFHTSAQEFSLFELARVFCSDAQKIKYDLEPWAQQQFAALGNVEERFIRENQEILALHNRVSDGYDNMALSSGEIMAKQRTAFTEEIKEIETLFARLDYEIQGLTGKVADVEEGVEVFERQVSRLEEKAEELRIQLETESWIHWLVRTVTGIGTGPNILQAVDQKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z229</accession>
    <name>A0ABR3Z229_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_003559</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000086">
        <property type="protein sequence ID" value="KAL1894668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="3"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="31"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="77"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="169"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="902"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="169"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1894668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1043" mass="112651" checksum="E2853F8EA47D3490" modified="2025-10-08" version="1">MPVFCAYCGKSFTRKEHLERHIPSHTNVKPHRCSGCHLSFTRRDLLQRHHTTYHEVRDPLDPSPAGIPSITGRTPIACQNCANAKTGCDKRVPCSRCTDKNLPCAARFARRSSKAAVRAAQNTVMSNAFAQAQAQAQAQVQAQAQVQTQMTQMVFLDVDGMNTDQRQCQQHQGSHAQVNESTRGILAESQSPKTSKQQLSPKLPSPPLIDDFMQINPGTFASSTVPYPDFLQWPQEYSLDMLYDNGSGMILSRPDIPMPCFNNIDDLSMSSESINDGSSSSASIHTRGSSTVFANEFDSHFKSAIEPAIAPAVGAAATSTSIEPNSPAAESISEFSVVISAESAWPLARCNPPTYSADCPRTAIVHLECLEHRLNGSDSSWAALEKFLGGDSLSATATVVAPLSQGTRDRMLAITQSFLHKALDIHRGSVVEQTKQIGQPSPANFNLVMLPPNNILQHFLQRHVRSMASYLPLVMGGCLDVNDMVFSNQSLTLLVLLMIAQGAAAVPLAQARFLSAGLTEICRISLFDTIEKNVEFSANPVALQGALLFTVLGAWSGDKWLMDIAMGQRGMYLSMLRHAGMLEPASPSLPSRTSIGSIGSNVNGGSNACGNTVEQQWQAWQQTELRSRLAYNWVMMDQELALFHDASPLLATTDLRCYMPAPESVWLAKSVEQWALEMQNNSQPKRTPSDQEISAGALASPCSLYDLFQDFLHDNISSRQNPLTPLHLRLLLHPLQSTLGHVSQLLTCFSDATAASTWPRASCAAQESTLARLDEVQNLLQKWYHLAISAFTAQPADDTVQASLVLYHLIYLNSVTNFAEIEKLARKDGMGPGLWNPSQSHKQCIFNRGEAVVHCGQVLRLVRAMDLAQRPAWWSAAVYRAILILWANAMISKKGSSFQTQAQASSSSPMAAPGSASAGSGSPGSQLSPQSSMTSPSVSLVSAASGSVSGPISGPVFGPVSDICIDQILPEDAMAGYLRAGEGVPLLSSKSGSNIALDQPSEILGYGVMLINEGLGTRIGDGLKRKLETLGGNWMCNAVVDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z260</accession>
    <name>A0ABR3Z260_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">54S ribosomal protein L7, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">mrpl7</name>
        <name evidence="5" type="ORF">Cpir12675_003792</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000095">
        <property type="protein sequence ID" value="KAL1894150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_uL5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_uL5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_uL5_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="RL5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL5 C-terminal" evidence="4">
        <location>
            <begin position="249"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1894150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="349" mass="38848" checksum="259A4AC28AEC249F" modified="2025-10-08" version="1">MASEGLMAVRGLMCSVSRRQLTTVTAINARCLSSSSRVAARDVLNEIEPNSSFSAPILEKADIEAFDTETRVKNREAQLPGKRFQYHPPKYDRGPLHPVQSPKHSDPVARDFIPGPFNQPRLRETFQHTISSDILTLTYQHTIPGTPAKPERERLRAWDDSSPYHVNRPLRGPRGAGTLPILEKDIKFHNIPEIRSVHIHCFQPQAGVDPGYLAVCRAIVMAISGRMPKVTWIKNQVSQWKIQKGSLSGCKTTIFGNQAYEFVDKLATLVFPKIKDWPGIKGEGDGSGTITLGLNPTDMAHFPEVGVNYDMFPSKMIPGLHVMIRTTATSDRQARLLMQTLGVPMTGKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z355</accession>
    <name>A0ABR3Z355_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="7">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_003568</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000087">
        <property type="protein sequence ID" value="KAL1894629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="entry name" value="E3-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050743">
        <property type="entry name" value="2-oxoacid_DH_E2_comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43178">
        <property type="entry name" value="DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43178:SF5">
        <property type="entry name" value="LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE COMPLEX, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4 7" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="9">
        <location>
            <begin position="36"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="10">
        <location>
            <begin position="161"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="121"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="203"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1894629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="462" mass="50303" checksum="C132BEA4584052ED" modified="2025-10-08" version="1">MFMQRSTRVLRALPVTRQLALHQVRGFRILPALQAVKPVVLADIGEGIVECEIIQWFVQPGARVEEFSPLCEVQSDKASVEITSRFAGIVKKLKYEAGEMARVGQPFVEIDIDGSAEELGTVKQNEQKKEEEEEAKPAEAAQEAPADISAAEKKRLYTGAIATPAVRHLSRQHDIDITQIRGTGKDGRVLKEDIHGYLKTRDTPASQSQALDTPIPSGQQVESTVPLTGTQAQMFKTMTRSLAIPHFLYADEVDFTRLDSMRSRLNTVLTTLDSVGISKVSFLPFIIKAVSIALQRYPILNTRVEAGSGSKPQLIYRSQHNVGVAMDTPQGLVVPVIQDIGSQSVVSIASEVARLQALGLQGKLSPRDLQGGTITVSNIGSIGGTYVSPVIVDKEVAILGIGRMRKVPAFGGEDGKSIVEKCVCNFSWSADHRVIDGATMARAGDLVKKLVEEPELLMVQMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3Z4</accession>
    <name>A0ABR3Z3Z4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003453</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000082">
        <property type="protein sequence ID" value="KAL1894959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040976">
        <property type="entry name" value="Pkinase_fungal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248:SF2">
        <property type="entry name" value="FUNK1 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248">
        <property type="entry name" value="FUNK1 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17667">
        <property type="entry name" value="Pkinase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="2">
        <location>
            <begin position="89"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Fungal-type protein kinase" evidence="3">
        <location>
            <begin position="400"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="547"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="565"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="727" mass="82621" checksum="89F70A76C7A87C5B" modified="2025-10-08" version="1">MATSDTPELSACSTPTPTAKVLSQSTFFQERRASALPSPAEIRALNEASGHWRAASLNHPPPVIVPSLGLAVKYEANVTIAEVEAQVLMRERLQGRVPVPEVFGWDEDSGQEFIYMSLVEGDTLQARFSTTSESERQAVCKELRSMMNAWRALTQESDRYIGKRPLNEIFVAGQQERVGPFLGADAVQKFHDTCGIDIIDDIPIIFTHNNFCPPNILLLCGLNLKVVGIIDWGQSGWYPSYWEYCKARRVGIVDEEFNPALQEEWNTRYLPEVIDTVDDERFYHPWLEQEVILEGVLTAHDGKKLTAFPKVPDEKSVWDWLRSLEECFLDHAPYKFHTTKTVNQFKERKGQIIIFLQRSAAEDSGTFSYKHVLVVEEQKKSYDTSRFKADFLQLTCYIRGAYSSGTFDIHDEPDKLARALVGYATMDDDTMGLDKFFERRDGHRYVTLDDANGKETRLRLDKAMIQQKAIVCRGTTCYEMQDSHVAKFSWALDKRKLQVEQLKLAEAMGVEGMARVVAHRWITTITEMREGLQFPVARRFRGEDIRFDNPSTTMSMSSKRKSSADRTSGNASGSKRQRFIGQKSKLATVLNNQLPISNTKSSLYTPGEDLRVISEFRAIKELLESERDAIKAHRSLYISGEILHRNISSDNIIITNSETANGFKGMFTNLDLAIVRDSGPSGARHRTSTMQFMALEVRSRMDHTCRHGLESFFHVLLWMCAHQPSME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z404</accession>
    <name>A0ABR3Z404_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ubiquitin ligase (Cullin) of SCF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CDC53</name>
        <name evidence="5" type="ORF">Cpir12675_003235</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the cullin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000073">
        <property type="protein sequence ID" value="KAL1895374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1310.10">
        <property type="entry name" value="Cullin Repeats"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.130">
        <property type="entry name" value="Cullin, Chain C, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045093">
        <property type="entry name" value="Cullin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059120">
        <property type="entry name" value="Cullin-like_AB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016158">
        <property type="entry name" value="Cullin_homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036317">
        <property type="entry name" value="Cullin_homology_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001373">
        <property type="entry name" value="Cullin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019559">
        <property type="entry name" value="Cullin_neddylation_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11932">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00888">
        <property type="entry name" value="Cullin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26557">
        <property type="entry name" value="Cullin_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10557">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00182">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00884">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75632">
        <property type="entry name" value="Cullin homology domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50069">
        <property type="entry name" value="CULLIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cullin family profile" evidence="4">
        <location>
            <begin position="409"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="766" mass="88318" checksum="1EF54C383238526A" modified="2025-10-08" version="1">MAALPYSMPTQPNKNDIESTWKFLEVGIDRVMNDLERGMNMQIYVGVYSAIHNFCTAQKATNSVSFSNGGSVHRGAHLLGEEIYNKLNQYLTSHLEELTEKSEAYSDEALLALYNKEWNRYTTAAKYIHHLFRYLNRHWVKREMDEGRKKVFDIYTLHLVRWRTVLFDKLNGQVMQAVLKLVQSQRCGETIEYTQIKQIVDSFVALGLDDADTSKSTLDVYRYHFERPFIAATTQFYQAESKKFIAENSVVEYMVKAEARLEEEEERVKTYLHQDLGPPLRKACNDALILEHSTLLREEFQVLLDNDCEEDMARMYNLLSRIPDGLEPLRLRFETHVRKAGLLAVQKVASDSEKLEPKVYIDSLLDIHTRYQGLVKRSFNDEPEFTRALDNACREFVNRNVVCKAGSNKSPELLAKYTDVLLRKGSNSVSESELETALNQIMTVFKYIEDKDVFQKFYSRMLARRLVHSNSASDDAETSMISKLKEACGFEYTNKLQRMFQDIQLSKDLNASFRNHLADTETKTVTDSTFSILGTGFWPLTPPSTNFTPPVEVSADCERFYRFYKGNHEGRKLTWLWNLCKGEIKANYCKNAKIPYTFQVSLYQMAVLLLFNETPTYTWEDMISATQLQSEVLEGALAVILKGKVLLMSPSDDKPGPGKIFKLNTDFKSKKIRIKLDVGGVKEAKQEEVETNKTIEEDRKILIQSAMVRIMKARKTMKHAQLVSETINQIKSRFTPKVADIKKCIEILMDKEYIERLDDDIIGYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4Z3</accession>
    <name>A0ABR3Z4Z3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Protein translocase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">TIM44</name>
        <name evidence="9" type="ORF">Cpir12675_003397</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tim44 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000079">
        <property type="protein sequence ID" value="KAL1895125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039544">
        <property type="entry name" value="Tim44-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007379">
        <property type="entry name" value="Tim44-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10721">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10721:SF1">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04280">
        <property type="entry name" value="Tim44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00978">
        <property type="entry name" value="Tim44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Tim44-like" evidence="8">
        <location>
            <begin position="337"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="70"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="71"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1895125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="497" mass="55792" checksum="48F5AE428B7EE1AB" modified="2025-10-08" version="1">MQRITGSRHSALRRAIALAETAPTRVSALAILSQPSTTSTSISATTRLTSPFVPKFLGCQTRQLHVTSRLLQEDKKDEKKDNKEEAEGETKDGDKNKDDKKDEKKEDLPPPPPHGDKTPWEVFRETMQSEFQKSQEWNESTKALASSAQEFTESESVRKAREAYEKSTGAVSSVASSAVRNTATAIGKGAQWTWETPVVKGARAAANVTGEALDKATKPIRDTEAFKNVKEAIDDGSSARYGGWVEKEERRKRRADHMAKNPAASEVLQENPDAGTNVTLHKDSAWKESWREFRDSSSVVQGLFNMNKTYQESENPLISTARSITDTIAGFFAENEQALVVKKFKQMDPNFRIEPFLNELRDYILPEVLDAYVKGDVATLKEWLSAAQFSVYEAVTKQYLTMGMKSDGRILDIRNVDVLKARMLDPGEIPVFIITCRTQEVHVYRNAKTDKLAAGMEDKVQLVTYAIGITRTPEDVNNPETRGWRIIEMQKSGRDWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5Y8</accession>
    <name>A0ABR3Z5Y8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">RING-box protein hrt1</fullName>
            <ecNumber evidence="13">2.3.2.32</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">HRT1</name>
        <name evidence="13" type="ORF">Cpir12675_003136</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.32" evidence="13"/>
    <dbReference type="EMBL" id="JAWDJO010000069">
        <property type="protein sequence ID" value="KAL1895745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061663">
        <property type="term" value="F:NEDD8 ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16485">
        <property type="entry name" value="mRING-H2-C3H2C2D_RBX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051031">
        <property type="entry name" value="RING-box_E3_Ubiquitin_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024766">
        <property type="entry name" value="Znf_RING_H2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11210">
        <property type="entry name" value="RING BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12678">
        <property type="entry name" value="zf-rbx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="13" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="51"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1895745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="117" mass="13238" checksum="3A69BC98EB837BA8" modified="2025-10-08" version="1">MADVNMTDAPGTSSKKSPAADKSADNEKKNFEVKKLHAVALWAWDIVVDNCAICRNHIMDLCIECQANHGSATSDECTVAWGICNHAFHFHCISRWLKARQVCPLDNRDWEFQKYGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6K9</accession>
    <name>A0ABR3Z6K9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphotransferase</fullName>
            <ecNumber evidence="8">2.7.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">GLK1</name>
        <name evidence="11" type="ORF">Cpir12675_002864</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the hexokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000060">
        <property type="protein sequence ID" value="KAL1896271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004396">
        <property type="term" value="F:hexokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.367.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001312">
        <property type="entry name" value="Hexokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019807">
        <property type="entry name" value="Hexokinase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022673">
        <property type="entry name" value="Hexokinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022672">
        <property type="entry name" value="Hexokinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443:SF30">
        <property type="entry name" value="GLUCOKINASE-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443">
        <property type="entry name" value="HEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00349">
        <property type="entry name" value="Hexokinase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03727">
        <property type="entry name" value="Hexokinase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00475">
        <property type="entry name" value="HEXOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00378">
        <property type="entry name" value="HEXOKINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51748">
        <property type="entry name" value="HEXOKINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hexokinase N-terminal" evidence="9">
        <location>
            <begin position="8"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Hexokinase C-terminal" evidence="10">
        <location>
            <begin position="226"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1896271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="507" mass="54802" checksum="6D256F7872F20B1C" modified="2025-10-08" version="1">MSLEAATTKIVDQFEVSDESLNSSVKEFLQQMEDGLASDNTSLAQIPTYVTGVPDGSEKGLYLAVDLGGTNFRVCSIQLNGDSSFNLTFNKVAIPKELMVAKTARELFSFLAKQIDIFLKEHHADHFTSKDRTRHGFFGDSEQKVFQLGFTFSFPVQQLSVNSGKLIRWTKGFDIPDAIGKDVCALLQTEIDRLGLPVNVAALVNDTVGTLMARAYTSVGKAKCILGGIFGTGTNGAYLEKLSNIKKPIVGEYSKATGEMVVNTEWGSFDNQLNVLPQTPWDETLDKMSVNPGSQLFEKRVSGMFLGEIVRLAVLDLLTDPEVHFFQDTNSSANDWKSTTSIGSHSGFFSQWGVDSSIMSVAAADNTPELSTLRQSLEGNLEVYTPSLEDAHVFKAIAHAVGRRAARLSAVAIAAIAIKSGKLDDPNEEIVDIGVDGSLVEHYPFFRDMIFEALRSIEGIGAKGAEKIRIGIAKDGSGVGAALIALVAAKAHRRNSLAPPAIRCGSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6Z9</accession>
    <name>A0ABR3Z6Z9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">40s ribosomal protein L44e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL44</name>
        <name evidence="5" type="ORF">Cpir12675_002814</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL42 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000059">
        <property type="protein sequence ID" value="KAL1896410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000552">
        <property type="entry name" value="Ribosomal_eL44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053708">
        <property type="entry name" value="Ribosomal_LSU_eL42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10369">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L36A/L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00935">
        <property type="entry name" value="Ribosomal_L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01172">
        <property type="entry name" value="RIBOSOMAL_L44E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1896410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="125" mass="14460" checksum="F53B3580B55A124C" modified="2025-10-08" version="1">MHMRGRRLYKTVIEYIAVLMVNIPKTRNTYCKGKECRKHTQHRVTQYKAGKASLFAQGKRRYDRKQSGYGGQTKPIFHKKAKTTKKIVLRLECVKCKAKCQLAIKRCKHFELGGDKKTKGAALVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z729</accession>
    <name>A0ABR3Z729_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_003296</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000075">
        <property type="protein sequence ID" value="KAL1895339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15481:SF0">
        <property type="entry name" value="LD23870P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15481">
        <property type="entry name" value="RIBONUCLEIC ACID BINDING PROTEIN S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="129"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="212"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="256"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="296" mass="32537" checksum="46BC429CE23C3B4E" modified="2025-10-08" version="1">MTNPRSPTPSRRSRSRSYSQSRSRSSGQSPSRSRSRSRSNSLSRGQSPDRRRRHHRSASYSQSPDSHRGRRRRLNSESKDKSRSRGRSRSNSRTRSSNSSKSGSRSRSKSWSQSCSRSRTRSPDHQGSTKVVVERLTKNVNEAHLREIFGQFGGINDLYIPKNNLGVNRGTAYILYFSEEDAEAAITHMHEAQIDSATINVSIVLKGSKFHHMPPQAQLGGSSSSARSGRNRKNNGGGGGRVGPPSGPRPGKGSRRGADIYRPGDGDKTTNAAPRRAAGNTRGGGKRASHMVWDRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7A3</accession>
    <name>A0ABR3Z7A3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000058">
        <property type="protein sequence ID" value="KAL1896463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="87" mass="9324" checksum="30001E8B5D24DD3D" modified="2025-10-08" version="1">MSQISSGCVTGLLVGIAVSMISKVIIFIAGAVASGMVLAYRLGLNPVSHLKVPERYKLQKLAPRMMNRLPFKAAFSATFILAAFARI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z835</accession>
    <name>A0ABR3Z835_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_002681</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000054">
        <property type="protein sequence ID" value="KAL1896733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019433">
        <property type="entry name" value="GPI_ManTrfase_II_coact_Pga1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28022">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 2 SUBUNIT PGA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28022:SF1">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 2 SUBUNIT PGA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10333">
        <property type="entry name" value="Pga1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046697411" evidence="3">
        <location>
            <begin position="23"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="227"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="264" mass="28125" checksum="AD141A3952FBC444" modified="2025-10-08" version="1">MRLPLYLSFSLFIFIAPLPAAANTEKTIFSAPDARPIPLAHPTLADLNLPVLMPLPQNASQLRTHLAASAAGIPGMTNTPDTDLDEDGSHQDGGKAGNNAPSMFDTWMLLDNLTPGQRYEVRICWAATDPTDFAVAAYDIPTVFSTPALISSLADYANTLPPASSPASPSMSERSASVMFLRISAAADYVTSSAISSANRDPVLVLADVILDPFVYNIVPRSLLPTIAYLAIVAPLTLLLGRALAVWMVGCAAEVDEEKTKKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8K5</accession>
    <name>A0ABR3Z8K5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Sexual differentiation process protein isp4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_002567</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000051">
        <property type="protein sequence ID" value="KAL1896986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="390"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="470"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="535"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="563"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="645"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="677"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="711"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="739"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="763"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="790"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1896986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="855" mass="95685" checksum="559922BC704FB611" modified="2025-10-08" version="1">MEDNKSMHATTTHESAASKKETEIRIDSIVETPMGEILNATADDLLEVREKASGMTLEETVTLLKKIHKQFAQDPNFPLQVVTKIESFLANGDILKAPERYQAEIQEMKMEVALITNNSPYAEVRAVVDNHDDPSLPVSTIRVWIIGIFFSACIAFVNAFFDVRMPSIYVISTVPQLLAYPAGKAMERFLPDIGFTFWGVRHSLNPGPFNKKEHMLITIMSNVAKSVPATNYIVWIQVLPHYFDQPYALSAGYQLLIGLSTNFIGYGMAGMCRRFLVYPAYCVWPSSLVTIALNTAFHDTASEATSVKGPLKSVWTMSRMRFFTYAFIGMFFYFFLPNYLFSALGYFSWMTWIAPNNGTLQTLTGAYSGMSLNPVNSFDWNLFTYMIDPLVAPFFSTFNFFMGGFLSMFVVLALWYTNTYNTAYLPIISNQPYDHFGNRYNVTSIIDSRGIFDAAKYEAYSPPFLSAGSVSTYMFFFAVYTATVTYGILYHRHEICMGMRDLWDSIRGRSPAGPRKDALDVHNRLMSVYKEVPEWWYAVVIVFAITVGAVGIGAWPTNTSPAVVLYGVALCLIFVVPIGIIAAMTGVEVTLNVLAEFIGGAWVEGNAVAMCYFKTYGYVTCAQALSFASDQKLTHYLKIAPRFTFWAQMIPTLVSTFICVGVLQYQVNIKDICTSDAPFRFTCPGVNTFFSAAVLWGTVGPKKIWGQGGQYVATLVGFPLGVMVVVIFYALSRRYPRSTFLRAVHPVVALNGALLWAPYNLTYIWPAVPVAAFSWLYLKKRFLGLWSKYNYVLSAAFSCGIALSGIFIFFALQLPELKVEWWGNTVVGSGVDDGTRTLRTLASGEYFGPRLGEFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8M9</accession>
    <name>A0ABR3Z8M9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002834</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000059">
        <property type="protein sequence ID" value="KAL1896430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="238" mass="25730" checksum="9A9D780637561A19" modified="2025-10-08" version="1">MPSSINETSAPINSNYVPSELEALLSNAYTLVPSCLWDPDSSIFLCHTCKFPLQGYSIPPEWLDELSWPTANNILPPSCLLIPHSPADCYVHIFHATYNALMDGSRASRSAPGEPSALVNMNPIVSELVPQVQSQVQAEVEAEVTSPCQLRPTAPAFVSQPIASLRDMGSLGRGGSSRPQQMTSASIHPITSHDRKQPATSDLTHSPLAFSREDPNDVKVGAHHLASLLFSGYLQHHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8S1</accession>
    <name>A0ABR3Z8S1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein CASP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Cpir12675_002534</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CASP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000050">
        <property type="protein sequence ID" value="KAL1897009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012955">
        <property type="entry name" value="CASP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057476">
        <property type="entry name" value="Cux_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14043">
        <property type="entry name" value="CCAAT DISPLACEMENT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14043:SF2">
        <property type="entry name" value="HOMEOBOX PROTEIN CUT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08172">
        <property type="entry name" value="CASP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25398">
        <property type="entry name" value="CUX1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="686"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="domain" description="Cux N-terminal" evidence="14">
        <location>
            <begin position="27"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="CASP C-terminal" evidence="13">
        <location>
            <begin position="438"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="288"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="382"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="153"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="430"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="545"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="292"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="385"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF25398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1897009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="733" mass="81212" checksum="AD4F8E984EF2B499" modified="2025-10-08" version="1">MSVAADLAALEASISNPAANSGADNPQTNKFQEAISAWRAVNLNTLVTSLDTTASDIVTYQRDSTIQRKELAQKTKDFRKSDDATKLSEIKGLLKAYQTFIDLLTNHSKAVNSNFLKAYTSLSEVPDPYPLLEASVDSMLIAEDTLPKLTEENGRLQKSITKLTSQLEETEANLQTERNSHKDLEANLEKRVKDVESSWTLATEEKKGNWEAKEKALEEKIESQEHLIREIKASYEVNQRLGEGASQSTTSSGVTSAELQMLHSDLERASSRLTEVEARNEQLRIELAQAKSEASSQKTSGSLEDDPGYMRMRNENSSLIRKLDASRVERDGIRREFDGKFRNIEREIAHLIEERDSLKHKAERWSDYEDVKQELEVLKSIEFSTGDDDDEGQDSLDTSDLKAKGDTLEKLLLARNKKLSDELTILRVSHQDLQTRLQTLQNDMATTKGELVKAQTLNEKLENDLSNFQAEPSTHFSSGASVAGTYVSRYSPSVMGGRKGRVSPTSSIISGMPGERESPFGSLAPGNGATSSQAAGILPMITAQRDRFKIRNAQLEQELHDTHRAVSSLRQEVASLQRDNLNLYEKTRYVSTYNRSGGASHATTSSSAAATTSSLNANPSAVNIGSTGNPGIALDRYRKAYESNISPFAAFRGRESARAYKRMSLPERVVYSITRMVLASRTSRNLFAMYCLALHLLVFFVLFSMDESPAVPLHATSSDIDWKAKTKVNGALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9B2</accession>
    <name>A0ABR3Z9B2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">DNA topoisomerase</fullName>
            <ecNumber evidence="3 7">5.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">TOP3</name>
        <name evidence="11" type="ORF">Cpir12675_002510</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="3 7"/>
    <dbReference type="EMBL" id="JAWDJO010000049">
        <property type="protein sequence ID" value="KAL1897189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03362">
        <property type="entry name" value="TOPRIM_TopoIA_TopoIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="entry name" value="Topoisomerase I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="entry name" value="Topoisomerase I, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="entry name" value="Topoisomerase I, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034144">
        <property type="entry name" value="TOPRIM_TopoIII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390:SF21">
        <property type="entry name" value="DNA TOPOISOMERASE 3-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390">
        <property type="entry name" value="PROKARYOTIC DNA TOPOISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="Prokaryotic type I DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52039">
        <property type="entry name" value="TOPO_IA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 7 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="9">
        <location>
            <begin position="2"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Topo IA-type catalytic" evidence="10">
        <location>
            <begin position="168"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="527"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1897189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="660" mass="74275" checksum="781937DA12E4BB24" modified="2025-10-08" version="1">MRVLCVAEKPSIAKAVAGHLSGGRFEVKPSPVGWVKNYIFDYDFGLPWGTCSVTMTCVAGHMIDQQFTGEFKSWNFPPPDSLFSAPITKSVSSDKKGVAKNIKDQAKYCQALVIWTDCDREGEHIGGEIESIASQGNPRIEVKRARFSNIERAHILAAAPLRRLMPLDRRQIEAVDARMELDLRTGYAFTRFLTNTLKPLGGDLKDRMISYGSCQFPTLGFVVDRYFRVKNFVPEPYWSIKVTHKKDNINVNFSWARVRLFERLPTLILFERCLKAKLATITKVQERPTRKFKPLPLTTVEMQKAATRMLRMTGQEAMTIAESLYNRGFISYPRTETDRFDKGMDLESLIRNQSQDSTWGAYAGSLLDGRFDQPRQGKNDDKAHPPIHPVIYVSSKALKPEEARLYEYIVRRFLACCSEDAKGMATDVEMAYGDEVFMAHGLIVHEKNYLDVYTYENWTSSTQLPRFTVGEKLQPTEAMMTDGKTSAPNYLTEADLIALMDANGVGTDATMAEHIEKIQTREYVAVIDGPGKSSSSTRGARGRGSRGGRGGRVSGPGRASAGGTKYFIPTSLGVALIQGFDRMEFETSLGKPFLRKEMELQMKDICAGKISKQAMLDQQIRQYHQLYLESRDQVETLKTVRTRAAIIQLQPTQLRLGNTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9E2</accession>
    <name>A0ABR3Z9E2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dicer-like protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="primary">dcl1</name>
        <name evidence="24" type="ORF">Cpir12675_002572</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24 25">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="16 17">Belongs to the helicase family. Dicer subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000052">
        <property type="protein sequence ID" value="KAL1896924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd18802">
        <property type="entry name" value="SF2_C_dicer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.380">
        <property type="entry name" value="Dicer dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038248">
        <property type="entry name" value="Dicer_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005034">
        <property type="entry name" value="Dicer_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056755">
        <property type="entry name" value="DSRM_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950:SF62">
        <property type="entry name" value="DICER-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950">
        <property type="entry name" value="DICER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03368">
        <property type="entry name" value="Dicer_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24995">
        <property type="entry name" value="DSRM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00636">
        <property type="entry name" value="Ribonuclease_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51327">
        <property type="entry name" value="DICER_DSRBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50821">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="4" id="KW-0930">Antiviral protein</keyword>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="13 17" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="21">
        <location>
            <begin position="51"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="22">
        <location>
            <begin position="358"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="Dicer dsRNA-binding fold" evidence="23">
        <location>
            <begin position="548"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="domain" description="PAZ" evidence="20">
        <location>
            <begin position="795"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="19">
        <location>
            <begin position="993"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="19">
        <location>
            <begin position="1162"/>
            <end position="1322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00035116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAL1896924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1447" mass="163966" checksum="9D5E5CECAD90A72D" modified="2025-10-08" version="1">MTDDLISFSPSPSPKLRQYGSDDDDGSAFQLHDTLAASELPSLDQGPSTSGSGKTLISVLLLRYIAEQELEQRELGLEKRVSFFLVEKVPLVHQQFHVIKNNLPYAAIPIWGGSDNRPRSKEEWSSDMKSNMIIVCTASILQKALASTYVKMSQINLLVLDEAHHAKKNHPYARLIKDYYLCEPEATRPRILGMTASPVDTQDDIQLAAQELEMLLCSTISTVREGTLSTGVATSNHNHIKIQYDCLEPPSRTEFVNSIAQFLNLSQELRKLLTFSELAMSTLGRWCADRLWKLCITEAEMLRLIAKNEALHSLKDRKQITRTDHLRAIYDAIQNLELEPLKMDNRQLSSKTIVLLETLNGIFQNSDNHKCIVFVDMRYTAMMLDDVVKQPFIKNPRIKAAVLLGVSVNSARMSHREQNLIIHKFRQGRLNCLFATSVAEEGLDIPDCDTVIRFDLYRTMIQYIQSKGRARQKNSVYYTMMETGNIDHIRKVVSATRNTDILRRFCAQLPDDRIIEDPYITFERYSKEQAHISYEIQSSGARLGWVESRSILERFAAHLATTEQRNCGQTPRPEYSVIKSGKGYYCHINLPSTSPIQSHRGSLQSSKPAAKCSAAFETCIQLINQNFLDEYLEPIFKKSLPAMRNARLAITKKNKTGYNMIAKPSAWDKSRSHELSGDPLHGVAITLSTPAILNEESTILILLLYEKLPSLPDVHLFFGDGRNSFAQIRPLVGTVEKSKIPALKNFTLRSFRDVFSKDFVPETANLPYFIAPSNKTHDSYSPDLEVSEMINWDIVDACLSNDYLQIGSEAPEDFFKDKFCIDPYDGGRKLYLRRVRPDLHPLDLVPDGVPSPKFRDWKNVTHNIKEYSISLWGPSRAKRTWSNDQPVVEAVQMSLRRNLLEDVQDGDNDRQTHLPCFVIMEPLRISAIPPSTVTMIATFPAIIHRIESTLIALETSSMLGLSIRPDLALAAVTKSKESANFPMAGQRSAVDGDYERLEFLGDSFLKMATTISLYTLIPSSNEFEYHVERMMLISNQNMFMNALKLKLYEYIRTVKFDRRGWYPHGLVLRQGKSTTSEHTHSLGDKSIADVCEAFIGAAYISASQSSEKLATSSADFDMAVKAVSVMVNHDYHRMTAFKNYWEAYKTPPWLQATPTVPQVDFANKLSNITGYKFKNPLLARSAFKHPSYPWEDVPHYQNLEFLGDALLDMATIDFLYKTFPKEDPQWLTEHKMAMVSNRFLGCLSTELGFQSCLLITSTHIMKNIANYSDQLQSARFLAEEHAKASGSSNIEKNYWVDELLNPPKCLPDIVESYVGAVFVDSGYDYSTVHDFFTKHIKPYFEDMALYDSFASQHPITFLTKRLQSEFRCQGWDIKFKEQPVDLDAGAQVLIESRVVAGVYVHEQVVYTGESDNARFAKIQAAQGALAVFKDMARKQFELEYGCCCSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA48</accession>
    <name>A0ABR3ZA48_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosomal protein S21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_002314</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000044">
        <property type="protein sequence ID" value="KAL1897526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052837">
        <property type="entry name" value="Mitoribosomal_bS21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001911">
        <property type="entry name" value="Ribosomal_bS21"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41237">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN MRP21, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41237:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS21M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01165">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="58"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1897526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="221" mass="24518" checksum="0475BF01934D37FE" modified="2025-10-08" version="1">MERLIEEILASFTVSTLLRGPVPWRSIATAKPYPLASTTRVFSSTALRPDVTSDWVKSKIFGQSNPKPSTGNESTKTSGDSGSGLVSPSQSPPQTPNPVIWGWKGGIDRSGLTSLLNTDQQISGLSNPLPKRPRYKQAVRLAPSTGRTVHLTGHTDASMALRILNTRVRQNGLPKLVRLQRTHERPGLKRKRLKSERWRARFRESFLSTVSRVQALTKQGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAL2</accession>
    <name>A0ABR3ZAL2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Probable endonuclease LCL3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Probable endonuclease lcl3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_002391</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000046">
        <property type="protein sequence ID" value="KAL1897287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016685">
        <property type="entry name" value="Silence_cplx_Nase-comp_TudorSN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016071">
        <property type="entry name" value="Staphylococal_nuclease_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12302">
        <property type="entry name" value="EBNA2 BINDING PROTEIN P100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12302:SF2">
        <property type="entry name" value="STAPHYLOCOCCAL NUCLEASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00565">
        <property type="entry name" value="SNase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00567">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017179">
        <property type="entry name" value="RISC-Tudor-SN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00318">
        <property type="entry name" value="SNc"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00333">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50199">
        <property type="entry name" value="Staphylococcal nuclease"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50830">
        <property type="entry name" value="TNASE_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50304">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TNase-like" evidence="9">
        <location>
            <begin position="4"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="TNase-like" evidence="9">
        <location>
            <begin position="168"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="TNase-like" evidence="9">
        <location>
            <begin position="318"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="TNase-like" evidence="9">
        <location>
            <begin position="485"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="domain" description="Tudor" evidence="8">
        <location>
            <begin position="702"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="612"/>
            <end position="646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR017179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1897287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="884" mass="98634" checksum="244E7CB0A4896E4B" modified="2025-10-08" version="1">MALSPFFAKVKGIISGDTLLLCHPQRPQDERTFSLAYVTSPHMRREGDEPFAFQSREFLREKLIGQMVHCTPLYTVPALKREFGTVQYGGKDGPMLPDEALKWGWLKVRDEAGRKDDDEETLTHLDKLRSLQDQARLDDLGLWAGSGGYLTTQHDLGGPSFLEEYKGKLMDGIVERVLSGDRVLLRLLASESKHFNVMTLVAGIRTPTTERTLSDGSVQPAEPFSNEAKKFVEERLHQRAVKVFIAGMSNQGQLIASLLHPRGDISVFLLEAGLARCNDFHSTMLGEKMAALRAAEKKAQSQKLNLHTNHVSRNNEGSTSDMVVSRIVSVDTIFVRTKAGTEEKRISLSSIRAPRVNEPSEAPFRDMAKEYLRKKLIGKHVRVVVNGHKPASDGFEARDIATITEKGKNINLALVEDGWASVIRHRADDSDRAPNYDELLAMQEKAKSESKGMWSDKAPKGVQYTDMSESVQKAKIQLSTLQRQRKISAIVDFCKAGSRFTVLIPRENAKITLVLGGIRAPRAPRNNGEGGEPFGQEALDLANRRCNQRDCEIDVHDIDKVGGFIGDLYTNRESFAKILVEEGLASVHAYSAEKSGNATELFAAESRAKEGRKGMWHSWDPSQDQDDSYEKPSRSSGATDAAADVVPDKKPSDYREVFVTHIDENGRLKLQQVGPGSAALETMMNTFQTFHNDPRNNSSLTEVKVGDFVAAKFVDNRWYRGRVRSNDRTAKVADVVYIDYGNSQKIPWAKLRPLTEQFSKEKLRPQAVDALLAFVQLPTATHYLSETINALLDETDGKKLVALFDHVDAKEGMNYVSLYMPGAGPFESLSRDLVGEGLAMVARKPKPWERNPAYNAYLKALKETESQAKSDRRGMWEYGDITED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB24</accession>
    <name>A0ABR3ZB24_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Vacuolar protein sorting-associated protein atg6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">atg6</name>
        <name evidence="6" type="ORF">Cpir12675_002667</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the beclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000054">
        <property type="protein sequence ID" value="KAL1896719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.40">
        <property type="entry name" value="Autophagy protein 6/Beclin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007243">
        <property type="entry name" value="Atg6/Beclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038274">
        <property type="entry name" value="Atg6/Beclin_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041691">
        <property type="entry name" value="Atg6/beclin_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040455">
        <property type="entry name" value="Atg6_BARA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12768">
        <property type="entry name" value="BECLIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12768:SF4">
        <property type="entry name" value="BECLIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04111">
        <property type="entry name" value="APG6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17675">
        <property type="entry name" value="APG6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Atg6/beclin coiled-coil" evidence="5">
        <location>
            <begin position="161"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Atg6 BARA" evidence="4">
        <location>
            <begin position="292"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="98"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="379"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="164"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1896719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="541" mass="59855" checksum="F4F1E990C7F7058E" modified="2025-10-08" version="1">MFCQKCRAPLALDPSIGDLKSAAYDLLVATSSQEASSNSTLPSQPSYPQDEQRQNLLQSVAENSPGPIFRRQGGPDHHDHSRDAAMSFIQLADHHYALPIPKSPSTTRRRSNSRTKSSRPSSAQQNQAISNEYTEASKVHDMERVNKLFEILSARSDIDHPICVECTDLLVEELQKKLETATKERDTYIAFIKQVQDEEPTEAELKAQIEELETQKAAEAAITAELLELEKEKAQLDAELLGLEKESQEMDAQEEAFWMDRNEFADKLAGFQNERDSVNSMFDHDSRLLEKLQRSNVYNDTFCISHDGTFATINGLRLGRLSNKPVDWSEINAAWGHALLLLDTVARQLQYRFVGYELQPMGNTSRIIKLDISAPSSSRQAASSLSRSGSRRAAGSSIPSGNAGAGSTAEPDNLAGSSSLGSPHDHATPVKRTTLDLFSSGDMPLGLTFMHRRFDTAMVAFLELVRQLGDFVRRESTRLGRPLELPYKIDGDHIGNISIKLGIAHDDTWTNACRYTLTCCKFLLAHASNVQSAASKARSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBP1</accession>
    <name>A0ABR3ZBP1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kelch repeat-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">KEL3</name>
        <name evidence="3" type="ORF">Cpir12675_002034</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000036">
        <property type="protein sequence ID" value="KAL1898086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025183">
        <property type="entry name" value="DUF4110"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052588">
        <property type="entry name" value="Kelch_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46063">
        <property type="entry name" value="KELCH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46063:SF1">
        <property type="entry name" value="KELCH DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13422">
        <property type="entry name" value="DUF4110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4110" evidence="2">
        <location>
            <begin position="590"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="513"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="516"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="568"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="686" mass="77719" checksum="73AE4FDBB3609D6E" modified="2025-10-08" version="1">MGKKDKKDKADSKKAKLAEKKAKQANKAEKKAKNKAAKDDSDAEDIDLDDVLNEYKRQQEQFLKVTETICEAPPRARSASTLMASPCNRNNLLLFGGEYFNGAMAHFFNDLHIYNIDRDEWRCVTSPNTPLPRSGHAWTRASNPNHVYLFGGEFSSPKQGTFHHYSDFWRLEPAAREWTKIECRGKTPPARSGHRITYWKHYIVLFGGFQDTSSQTKYLADIWLFDTQNYMWHSPSLPAAQIKPDARSSFTLLPHEGGAVLFGGYSRVKTAVAANKQSKGHSQGSRNILKPMIHQDCFLLRITLPAENSPANTPPGVRWERRKKPANTPMPTRAGATMTFHQGRGIMFGGVHDVELTEEGMDSEFFNQMFAWNIERNRFFPLALRKPRANAGKKSNAPAEPRVNRRGRAQAAEDELLRNLAALETGVSLENADQLTLDKREEEKEEDIKPIREMVVTNEFPHARFNAQLAVQDDVLYIYGGTFEKGDREYTLDDLYAIDLGKMDGCKEIFKRENEDWVQSEDEDDDDDDDDEDDEEEEEEDDDDNEQPAVPLITPSKRGKKPRVTDGAEAEEAPTSVVEEEETEATTIIDDGLPYPRPFESRRDFFARTTNEWQDILISKLQVKGSEGGAALTVKELKTSAFELSESKWWGCREEIAALEEEQEAAGITEVVSLADRGDAGTHRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBR7</accession>
    <name>A0ABR3ZBR7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">U3 small nucleolar RNA-associated protein 14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_002189</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000040">
        <property type="protein sequence ID" value="KAL1897764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006709">
        <property type="entry name" value="SSU_processome_Utp14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14150">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14150:SF12">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 14 HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04615">
        <property type="entry name" value="Utp14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="397"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="533"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="720"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="764"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="51"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="87"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="111"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="135"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="198"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="437"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="458"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="471"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="482"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="533"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="545"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="595"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="673"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="731"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="796"/>
            <end position="809"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1897764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="971" mass="107522" checksum="7A04C2C1F8FF4ACD" modified="2025-10-08" version="1">MPGRQSHGRQSHGRPLTTGPKKKTAAPNRRSTARAQATVLDAYNIAAKQFPQKEKRTPRSRFMDLEEDENESEETAEASRRNRHNNDEDDDDDGDEDDSRPAQRRGRREDDGSDVEYGSDESGNEWRINGRIHEDEDSELDSDEAFGESDQEMFSGYAFGGSTSKSKKKNSDDEEEYNSDTSSLGSDAVDLATALDMAEAESSEEEAQEADSESASNSEDSSSEENSEQDSSDEESDDDVDGPTKQKVTLKELASEFAGFDDDDDDKAISAGKQKISLGDLGLIKTRDANIRKSVKLLSKEEAGPRGANAKLAIPLAPLQQAQVTRKVAFEKSAETLDRWTETIKANRRADHLQFPLLQDTPNASLSSKEFRPITAANASNELEKTMLDLLAQSGMSLERPKKKPMDDQGNELTPEQVAELVNKRRREREMGSREQKRAKRIKKIKSKAYHRIHRKQAQKDEMAIRAEMEANGELDSEAEREDAARKRALERVGARHRDSKWAKANSRTKRAVWDTDYREGIEDMARREIELKRRIEGKDSSSDYSDDDDSDNDSDASGEDNDADEKARLRRQLAKLKAERDNDGSSSQLNKMDFMQRVESQRAHENDTMIREIERMLASDNEEESDPENMVNGQVGRRSFGGARTNEARIETAMDVDSDSDAANERPKKVAKTAASKSAPVAVSALIRKSDQRKAAGRAATEAEDDEVEFVLDNKGADLNTGDAWATVARSKKPSRKSKVAASSRAVELDISSATAMVLSGGGDAAVASGDAVPATPSSRPVKKQTKTPVADTGADTSSAEGSDSESGNAIHHPLALRSERDLIARAFAGGDVVEKVFEAEKEEVIAEQEDKVVDNTLPGWGAWVGDGISSREANKHKGKFTTTIAGVKRKDRRDAKLARVIINEKRVKKNDRYLASQLPHSYETADQYERSIRMPVGPEWMTKETFQASTKPKVLLKQGIIKPMSRPMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCH2</accession>
    <name>A0ABR3ZCH2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein-serine/threonine kinase</fullName>
            <ecNumber evidence="7">2.7.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PKP2</name>
        <name evidence="9" type="ORF">Cpir12675_001931</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the PDK/BCKDK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000033">
        <property type="protein sequence ID" value="KAL1898386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.20">
        <property type="entry name" value="Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036784">
        <property type="entry name" value="AK/P_DHK_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018955">
        <property type="entry name" value="BCDHK/PDK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039028">
        <property type="entry name" value="BCKD/PDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947:SF25">
        <property type="entry name" value="[PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10436">
        <property type="entry name" value="BCDHK_Adom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69012">
        <property type="entry name" value="alpha-ketoacid dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase N-terminal" evidence="8">
        <location>
            <begin position="11"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1898386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="425" mass="47440" checksum="1C73B95640C46163" modified="2025-10-08" version="1">MLMWVAKEARPISLRQLMVFGKNLTEARLIDSANYLRTELPTRLAHRIRDMQQLPYAVVSNKNIGEVYNLYYSAFDEFRKVKTVVDCDENDELCRIIRQNLQAHLTVIPKLAMGILESDGLMDPQALDNFMNTILRSRISRRVIAEQHLSLTETFHSSWFIPGMKLSASEYVGEVFIKCVAKDVVERCGKAVQDLVRSTYGPSVKIPEIRVAGHLTTSFPYILSHIEYIVGELLRNSMQAVAEQQLHHPELVQDPLPAIEVTICSSAQHVILRISDRGGGIPRDELPYLWSFSKGPKSKARLEALQRVPLMAATLAELQAGESRRLRDEIGRADLRAPSFATSTDPVAVSMPANSSNGSLTSLSSRPPDLRLGMGLPLSRVYAEYWAGSLDVHSLEGYGTDAFLHVPKLGNKNEQLATRATMDAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCI4</accession>
    <name>A0ABR3ZCI4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mitochondrial import inner membrane translocase subunit TIM50</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_001941</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the TIM23 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TIM50 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000033">
        <property type="protein sequence ID" value="KAL1898396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="1" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="1" id="KW-0811">Translocation</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FCP1 homology" evidence="3">
        <location>
            <begin position="182"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="95"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="115"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU365079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="371" mass="42047" checksum="730CA4CB7DC96FB6" modified="2025-10-08" version="1">MHTFRNRLVNRSLASFAFPPLVTQPPYRTHRLSTSAIEFPVASTKTTFQSETEHKLPKSSLKIPTVFSSDSQPSFQLLTNSLTETDRQCYKSAFIPKHKLKGARHTPPSFGRMPQNNSKNSSTQSSKKKKKTPLDLPSKPTGPPPQKADGKAYSIPSKESGGVPKPTVGYLAQASLHLQPLTSPRPILVILDLNGTLLWRPHRRNPTTFIERQHTRLFLNYLVKNFVVAVWSSAQPENVRHMVNHLFPKAERQQLAAVWGRDRFGLSENDYSNRVQVYKRLTILWDNLAVQESSIDGKPWDQTNTVLVDDSVEKARSEPYNSITIPEFVGQTETSHVLPQVHDYLNTLAFQGNVSAYIRKHPFKQDVNFEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCK8</accession>
    <name>A0ABR3ZCK8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endocytosis regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">LDB19</name>
        <name evidence="3" type="ORF">Cpir12675_002446</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000047">
        <property type="protein sequence ID" value="KAL1897259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024391">
        <property type="entry name" value="LDB19_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF76">
        <property type="entry name" value="PROTEIN LDB19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13002">
        <property type="entry name" value="LDB19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LDB19 N-terminal" evidence="2">
        <location>
            <begin position="176"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="524"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="545" mass="60161" checksum="0EB22C01F9CE0EEF" modified="2025-10-08" version="1">MHHRVSSFFRSSTETISAKARGLQSQLHKPQSQTQTQTRSQQSTPRQRQASYASSNASIDCVSVTDSSESVVPGNNNAATISTLTTTANKTPTKSSARFRTPAKKNLISFNFSRGSRSILAEPATGTLDCTIESPPAVLYGPAEDSSGALVSGLMRLTVHEPQLDINSFEACFNLTITQKKPYHSHCQDCASTTTELKRWTFFNVRKTLSQGVHEFPFSVLIEGHLPASTNAQLIKVSYDLKAAVILSSTQPPLSTSTKPIKFERTLEVKRSIIRPDGNHRSLRVFPPTEIKAEAHYSQYIYPTATNTLSLRMEGVTVRNEATQTLEYWKLRRATWRLEENVKSVAQACEKHATTSADGNSKTSALRNYTRVIGQKNMTEGWKTDYATDTGRIELDFEYGTVQPKPNSNGPIRYATDLKTAEGIEISHCLMLELVVSREWAPINRPELITHTGTGRILRMRYPVFLTESPGLGISWDNEAPPMYQDVPASPPSYPKKVLMPLISYAELEDLESYSVSDASISYDSEIGGSSRSSCASISNGPSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCL1</accession>
    <name>A0ABR3ZCL1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000032">
        <property type="protein sequence ID" value="KAL1898433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="498"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="546"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="447"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="498"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="559"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="606" mass="66752" checksum="F98B5A6CCEA1D17B" modified="2025-10-08" version="1">MAFQTRASQRVVLATETQQRESCASAPSQTSRSRRGTQTPTQVSPASQTWVLFPPVAGSEAHTTSSYLTINDSFKSHSDIGTSVDQSDLHSQSAHGNHHDFDDDEEEDEEDDDAELDVLDSHLADFRTIPNIISPASTTVLPVHDGLGSFRLPTHSTSRHLQEQLYAFEQFNPHNVHQNPTGAIRHNINAPITAEIDLENLEVAERNERIEAWKREHSRALLEEIQKETRRQRRISQASAARGKRPSMASASVHSEAIVEESEAGLATEDTEKMEWHEDSSENKTKEDATDDEEKPRGFLDRITKKVIKDMLDIDDHTLAILVGEAYVNDDDDTQATPRASSPVRGGPNMAKEDSSWQLRMVESVARELGLFVNTVTPHPHPGAFSMYKRVQQDRIPYAGLEVIPESTPAAPKQSLSLLESLSQSALQFKPSFSLLQPTNSDLPKATADRSGDTKKSQARAETEGHGNNERFTQEEWEKDLDIKLVFRYLRSRFVPGSSSSNISTASTNHPVTSSPMDPAAKAARIRQHHPLIGGRVPADRRAFKSTAPGSPVVLRHGSTCSQSTRRSARRSSASSRHYWDIGGSIGTGSVAATATNGPMGAWGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCM9</accession>
    <name>A0ABR3ZCM9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">40S ribosomal protein S24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_002378</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000046">
        <property type="protein sequence ID" value="KAL1897274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00545">
        <property type="entry name" value="Ribosomal_eS24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053709">
        <property type="entry name" value="eRP_eS24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001976">
        <property type="entry name" value="Ribosomal_eS24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018098">
        <property type="entry name" value="Ribosomal_eS24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10496">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01282">
        <property type="entry name" value="Ribosomal_S24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00529">
        <property type="entry name" value="RIBOSOMAL_S24E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="103"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="108"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1897274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="136" mass="15605" checksum="7519D8B858CB284D" modified="2025-10-08" version="1">MADVDTPVTLRTRKFIRNPLLGRKQMVVDILHPNRANISKDELREKLATLYKATKDRVSVFGLRTQFGGGKTTGFALVYDSPEAMTKFEPRYRLIRVGMATKIERASRQQRKQRKNRQKTLRGTAKTKGAKAKKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD57</accession>
    <name>A0ABR3ZD57_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-phytase</fullName>
            <ecNumber evidence="2">3.1.3.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_002002</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.8" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000035">
        <property type="protein sequence ID" value="KAL1898295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016274">
        <property type="entry name" value="Histidine_acid_Pase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963:SF23">
        <property type="entry name" value="3-PHYTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963">
        <property type="entry name" value="MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000894">
        <property type="entry name" value="Acid_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00616">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045991301" description="3-phytase" evidence="5">
        <location>
            <begin position="18"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1898295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="514" mass="55793" checksum="F8ECCC6469AE658F" modified="2025-10-08" version="1">MAPFFNTVVLLAAAANAVSVSPRSAYSSSSSANQILLAPEDAIKNPASTSAKEPLKHAGANGPYFAGPNVNKISSSVPDNCKVDRAAYVSRHGSRFPDTGAYNGWVSMYERFQAAQFTATGSLSFLKDWEPVLTNPSAQIAMESPTGWKEAYDMGYMLRTRYPDLYTDGDSFYTWANNYTRVIQTARNFARGFLGPRAEELGKIVSVTSKGYTGAIGNSLAPGDQCPAFSDDEGGSLAEAWKGIYIPPVQKRLQALIKGDLQLTSTDVAQMPYLCGFESQITGRLSPWCSVFTDAELLDYEYSQDLRYYYGTGPGKDLPPRIMMPFLDTLVKLLGASNGTTTGVDASGTAFEVPKLLTVFLNDGQLNQLVAASGVFDKQATLSSTKRDPSRLFVSSRYTCMRGGISWERMTCNITETQTTSKYAESKSKTTTTKEEVYVRVLLNDAVYPIPSCKSGPGSSCKLSDYTKYIADKYAAQGSWIKSCNVTTEGAPTKVQGASFFTDLSSAWIKTEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDA3</accession>
    <name>A0ABR3ZDA3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UDP-N-acetylglucosamine transferase subunit ALG14</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Asparagine-linked glycosylation protein 14</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ALG14</name>
        <name evidence="12" type="ORF">Cpir12675_001780</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">Heterodimer with ALG13 to form a functional enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ALG14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000030">
        <property type="protein sequence ID" value="KAL1898673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004577">
        <property type="term" value="F:N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013969">
        <property type="entry name" value="Oligosacch_biosynth_Alg14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12154">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12154:SF4">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE TRANSFERASE SUBUNIT ALG14 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08660">
        <property type="entry name" value="Alg14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1898673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="307" mass="33288" checksum="6B2D9BCB1AEAD586" modified="2025-10-08" version="1">MLSYTLLVGGLTVYAAQLLTMPIVFPMYLALGTSVVAAVNWALHGSVSIFVPPAFMCLFALAVLINVYRLRVMSHTAIRQSQRSPPDAKPSACQLYTLIVLGSGGHTKEMLYMMSRGFIPSPRAHRRYLISSGDRLSLVHLKEWEAVQEKAAASCLDNVTGRKGPPAGTFDVVTVPRARHIHQSLLSTPFTAAASIAMLVPALLKRPAARPDLGPPDLIISNGPATGFFTVLTAFSLRALALVPEEKMRSLYVESWARISTLSVTGRLFQLTGIADRAVVQHEKLSQKYGMENGGWLVLAKDGGKMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDK3</accession>
    <name>A0ABR3ZDK3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phospholipase</fullName>
            <ecNumber evidence="5">3.1.4.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_001764</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + choline + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14445"/>
            <dbReference type="ChEBI" id="CHEBI:15354"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="3.1.4.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the phospholipase D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.4" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000029">
        <property type="protein sequence ID" value="KAL1898761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09138">
        <property type="entry name" value="PLDc_vPLD1_2_yPLD_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09141">
        <property type="entry name" value="PLDc_vPLD1_2_yPLD_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016555">
        <property type="entry name" value="PLipase_D_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015679">
        <property type="entry name" value="PLipase_D_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896:SF128">
        <property type="entry name" value="PHOSPHOLIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896">
        <property type="entry name" value="PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00614">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009376">
        <property type="entry name" value="Phospholipase_D_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="7">
        <location>
            <begin position="216"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="7">
        <location>
            <begin position="650"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="728"/>
            <end position="752"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR009376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1898761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="864" mass="99759" checksum="8CE92F5189F7F3F6" modified="2025-10-08" version="1">MASGPDNPTASKSRFSMSSFKGVLQGAAQKIQENSSLQDAKVSLIHSKNKIGKFGNIFNRNHRHDEEHEKACDAKRTAICEQNRFKSFFPERDNNNIKWYVDGRNYFWAVSEALENATETIYIADWWLSPELFLRRPPLDNPQWRLDQILKRKAEQGVKIYVSVYREVEAALTCNSKHTKEALRALCPEGSPGYGNISVMRHPDHNVFENAADMTLYWAHHEKFIVIDYKMAFIGGLDLCFGRWDNNQHPLSDIHADVTSKEVWPGQDFNNNRIMDFKSVDDWMQNEISKDQHGRMPWHDVSMGLIGPCVYDIAENFVLRWNFVKRDKYKRDDRFDWLELRGRQGENEDLVAVQRPSHPVGEYIVHPITPIDTAAPAQNGTIRAQVVRSSDDWSMGILTDHSIQNAYSEIIQKAEHYVYIENQFFITATGNQQSPIHNTVGRAMVDAVLRAAQEKRKFRIIIVIPAVPGFAGDLRDDSAAGTRAIMDYQFKSICRGEHSIFEQIKAKGVDPKEYIFFFNLRSYDRLPRTKRLRDAEKVSGVKYSDVQRGAAEEVMADSLHPKENNWHGKKYYESLKEHNPASSRRGSNEEMAEALAFKRQFEKALAQTHVKDQPAIKPTLAHLTMYDQESVLDQFWPDDPKDEVQNWIQEELYIHSKLLIADDRIVICGSSNLNDRSQLGSHDSELSIVMEDTRPLQTTMDGKPYVAGWHAATLRRYLWREHLGLLRPQPHDASKDPNAQPPGPQSPNDPIEDETMQIVVDPLNDDLWKMWTEQATQNTEMFRHLFHADPDNYVKTFEDYDLFRPPRAVKPGHIFDPFLPPDDIRRKLDTIKGHFVWMPLEFLKDAEMAERGLQLNQFTESVYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDT9</accession>
    <name>A0ABR3ZDT9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Calmodulin-dependent protein kinase cmk2</fullName>
            <ecNumber evidence="7">2.7.11.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CMK2</name>
        <name evidence="7" type="ORF">Cpir12675_001877</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.17" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000032">
        <property type="protein sequence ID" value="KAL1898412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004683">
        <property type="term" value="F:calcium/calmodulin-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="23"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="319"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="390" mass="44257" checksum="2D3B0E2696EE0578" modified="2025-10-08" version="1">MLTTAWLNKLAGQPESYEKKSNYKFGRTLGAGTYGIVREADSPAGKVAIKIIMKKSVKGNEQMVYDELKLLQTLKHPHIVRFEDWFESRDKYYIVTELATGGELFDRICEQGKFTEKDASKTIKQVLEAVNYLHQNNVVHRDLKPENLLYQTRDLDSSLVLADFGIAKTLDRKDEVLTTMAGSFGYAAPEVMLKRGHGKAVDMWSMGVITYTLLCGYSPFRSENLQDLIDECTNGQVVFHERYWKDVSDDAKEFIMCLLRPDPSDRWTSERALNHPWLSGESATDHNLLPEIKAYMAKAKLRRGIELVKLTNRIEALKHLEEDPEDSDLPDQSTLTADQATDKPASPEGKRTLSKTIKGAIFREVVMAKVREMKQQQEADSKIQEASKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE70</accession>
    <name>A0ABR3ZE70_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">1,3-beta-glucanosyltransferase</fullName>
            <ecNumber evidence="5">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">GAS4</name>
        <name evidence="7" type="ORF">Cpir12675_001807</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Cell membrane</location>
            <topology evidence="1 5">Lipid-anchor</topology>
            <topology evidence="1 5">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the glycosyl hydrolase 72 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000030">
        <property type="protein sequence ID" value="KAL1898700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004886">
        <property type="entry name" value="Glucanosyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31468">
        <property type="entry name" value="1,3-BETA-GLUCANOSYLTRANSFERASE GAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31468:SF4">
        <property type="entry name" value="1,3-BETA-GLUCANOSYLTRANSFERASE GAS3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03198">
        <property type="entry name" value="Glyco_hydro_72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044993078" description="1,3-beta-glucanosyltransferase" evidence="5">
        <location>
            <begin position="18"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="437"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="496" mass="53848" checksum="7CD0AED3F586A9A4" modified="2025-10-08" version="1">MRAFYALAALGASLVAAVPTLEVQGSSFVNPKTGNRFQLLGVDYQPGGSAGYKPKEGEDPLTDADRCLRDASLMQLLGVNTIRVYNLSPNLNHDECASIFNAAGIYMAIDVNSPLVGESLTSWQPWTSYYAAYLNRTFAVVEAFKSYPNTLLFFSGNEIMNDNSTVDTSPAYIRAVTRDLKNYIKLHSDRYIPVGYSAADVRGILFDTWNYLTCTIEGEKDNESRADLFALNSYSWCGNSTFEKSGFNKLVDSFKGSASPIFFSEFGCNEVQREFTEVQAIYGQQMDSVFSGGLVYEWTQENNNYGLVKVNSNGSVSLLGDFNRLYEQYRLLNIDALQAKPAESTNEAPKCDPSMMTVKGFDTKWDIPSIPSSDGSDKLLEEGVSPAPVGKIVKISDFTVKHQFYDVNGKEMTGIKIKTVADDSFNYPGYSTLNFDSSASKSSSGSASSTGSVSSSASGSSTSSTGSTDDVSAATFVAFQPIVLGMAMSMALALTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEF3</accession>
    <name>A0ABR3ZEF3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Lipase 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">TGL5</name>
        <name evidence="7" type="ORF">Cpir12675_001841</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Probable lipid hydrolase.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000031">
        <property type="protein sequence ID" value="KAL1898637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07230">
        <property type="entry name" value="Pat_TGL4-5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021771">
        <property type="entry name" value="Triacylglycerol_lipase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF10">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11815">
        <property type="entry name" value="DUF3336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4 5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="6">
        <location>
            <begin position="216"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="5">
        <location>
            <begin position="247"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="658" mass="73428" checksum="5E961B52D801362B" modified="2025-10-08" version="1">MINIEPVLRFVKYSQSDNPASSPINFLPSSFNLVPYLFGALSDVRQHVSSLISSPSNRPSTGDIADTRKAAIESRMKEALTHEEWETAAKDLDVIEGNDTWQVSSNDEEARDWNPRRIKAEIRRLDEARSSGDLKLMVYLVRTALSRDLGGMGNRNLYRHSYIGTKSLIERYVDSAVQTIDAISDVAARRLPIEMTLQLLTRTIQQARQNFGRSALLLSGGATFGMLHIGVLKALHEADLLPRIISGASAGSIVCAVLCTRLDSEIPQMLQEFAYGHLDVFEKAGSKIGFIGHLQRLLLQGSWNDVDNLDRVMRGMIGDITFREAYNRSRRILNICVSTPSSHDMPRLLNYITAPNVLIRSAVTASCSVPLVFNPGKLWIKNPMDGKIQVWEPGSQTWVDGSLDNDLPMERLSEMFNVNHFIVSQVNPHIVPFLSKDNHLTSDQNQGSKLNPINVSSDWNYALGNVAIMEAIHRLQVMVDVGMAPGYCSKIKSILNQKYSGDINILPEINPKDLPCLLTNPTIDFMLRSCLAGEKATWPKIARIRERVSIEAALGRCLNTLKARVIASHEIYNYPKSSGSRKIGWKSSSVAFRPSHFLPLGLPLSPVSNVIDDSRRNWQKGRPRSSSEAEDSETLNFPITLHSSSSHFHLRLLTDHDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF20</accession>
    <name>A0ABR3ZF20_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Microbial-type PARG catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001574</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000025">
        <property type="protein sequence ID" value="KAL1899290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="entry name" value="Leucine Aminopeptidase, subunit E, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019261">
        <property type="entry name" value="PARG_cat_microbial"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35596">
        <property type="entry name" value="DUF2263 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35596:SF2">
        <property type="entry name" value="MICROBIAL-TYPE PARG CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10021">
        <property type="entry name" value="PARG_cat_microb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Microbial-type PARG catalytic" evidence="2">
        <location>
            <begin position="86"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="305"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="402" mass="44573" checksum="A0353060687DF800" modified="2025-10-08" version="1">MDQHPPPPPPRPNDIASQTKRKYLPIINEEYCHIWPQQSTTYRARDHSHDHLYDGRRISTNPHPPQFIIEARDPVTSVTYHRHMLQQHVPYLCGAHPKRPGGDWETGVPGSEEELCRRSSLSASLASAIRFYPLPGDGAIYSPNVVVFRGPADHYALLPRTEWFSVPVVSVAPVRLPKLNTNDPATAAPGGSGCGGPIRYSFAEERTQSRLAMKAALKAVLHQGFTSVVIGDFGLGRSARNPPRVMADMWRELFLYDPDIRGHFCRVVFAFTDTSICTEDLIYEAAARAAHKEASKGARRKSAHSHTAGSSSSSNGYVVPSRAAAQQYAGYAQYGYPDSSGSGAYYGHSQVDMYSGPPGPGGLPRQQRLTDYEIFRMTFQQTEIERVQSTRDPRYGLEMLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFE1</accession>
    <name>A0ABR3ZFE1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">TATA-binding protein (TBP)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tbp1</name>
        <name evidence="6" type="ORF">Cpir12675_001626</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000027">
        <property type="protein sequence ID" value="KAL1898967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04516">
        <property type="entry name" value="TBP_eukaryotes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00408">
        <property type="entry name" value="TATA_bind_prot_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000814">
        <property type="entry name" value="TBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030491">
        <property type="entry name" value="TBP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033710">
        <property type="entry name" value="TBP_eukaryotic"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10126">
        <property type="entry name" value="TATA-BOX BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00352">
        <property type="entry name" value="TBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00686">
        <property type="entry name" value="TIFACTORIID"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55945">
        <property type="entry name" value="TATA-box binding protein-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00351">
        <property type="entry name" value="TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1898967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="235" mass="25925" checksum="631591AC17127E05" modified="2025-10-08" version="1">MESLQSHPTSAAQAKAFTAPGSFSFPNGHNEDKSVNGTAVLPATPVATPVAKEVGSGLTPTLQNIVATVNLDCRLDLKTIALHARNAEYNPKRFAAVIMRIREPKTTALIFASGKMVVTGAKSEDDSKLASRKYARIIQKLGFNAKFTDFKIQNIVGSCDIKFPIRLEGLASRHHNFSSYEPELFPGLIYRMIKPKIVLLIFVSGKIVLTGAKVREEIYQAFEMIYPVLQDFRKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFX4</accession>
    <name>A0ABR3ZFX4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Coq1 putative hexaprenyl diphosphate synthase</fullName>
            <ecNumber evidence="8">2.5.1.75</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">COQ1</name>
        <name evidence="8" type="ORF">Cpir12675_001558</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.75" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000025">
        <property type="protein sequence ID" value="KAL1899274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052381">
        <property type="term" value="F:tRNA dimethylallyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001:SF69">
        <property type="entry name" value="ALL TRANS-POLYPRENYL-DIPHOSPHATE SYNTHASE PDSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001">
        <property type="entry name" value="GERANYLGERANYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1899274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="459" mass="49817" checksum="81EF0105A983DB6D" modified="2025-10-08" version="1">MLLRPRSTLAFARPFRTNNSTGLTPPSTLLAQHKLVERYLLNPRLNYQLQNAQPFHSTSAQSSAIAAAISVASKTVSNAMKTASIVGNLPVDPLRLVSKEMRSLTGNIRKLLGTGHPSLDRVAKYYTQSRGKHLRPMIVLLMSRAVSVCPKAETAPSNHNIDVNIAPNEILIEGLPDSPLTSFIPDAPAEFDEDILPAQRRLAEITELLHTASLLHDDVIDGSESRRGEPSANHAFGNKMAVLAGDFLLGRASVALARLRNPEVVELLSTVIANLVEGEFMQLKNTAQGEKAPVWSEDTLKYYLQKTYLKTASLVSMSCRASALLGGASAETVELAYTYGKNLGLAFQLVDDLLDYTQSHEELGKPAGADLELGLATAPLLFAWKTNPELGTLVGRKFSQEGDVTLARKLVLESDGVEQTRALAQSYHDKAVAALANFPESEAKQGLIDTAANILKRKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH29</accession>
    <name>A0ABR3ZH29_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pescadillo homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Nucleolar protein 7 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">NOP7</name>
        <name evidence="7" type="ORF">Cpir12675_001467</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
            <location evidence="4">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
            <location evidence="4">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the pescadillo family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000023">
        <property type="protein sequence ID" value="KAL1899351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17709">
        <property type="entry name" value="BRCT_pescadillo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03028">
        <property type="entry name" value="Pescadillo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010613">
        <property type="entry name" value="PES"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12221">
        <property type="entry name" value="PESCADILLO - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12221:SF6">
        <property type="entry name" value="PESCADILLO HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06732">
        <property type="entry name" value="Pescadillo_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2 4" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="BRCT" evidence="6">
        <location>
            <begin position="358"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="315"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="507"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="510"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="556"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="581"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="643"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="654" mass="74301" checksum="3CDD5B93C48ACCB1" modified="2025-10-08" version="1">MPPRIKKKGKAGAAKNYITRNQALKKLQLSLADFRKLCIWKGIFPREPRNRKKANKSSTYSTTFYYAKDIQYLLHEPLIQKFRDLKALEKKISKALGRGDVGDAKRLNENASRSESTGKARFTLDHVIRERYPTFNDALRDLDDCLSMLFLFANLPSTNSVPAKVIARCERLCLEFQHYCITSHSLRKSFLSIKGIYYQANINGEDILWLVPYKFNQRVTADVDYRIMGTFVEFYITLLTFVNFRLYTKQGLRYPPKFDQNKDNESAELGAFTLEGRGIVEESIPKQIAEPAAGHKVDPKTQAAVNNVVKALKSSSSGEETSAPANTEATENSNSIDKFEPVVAGGDVLPQPSYSSSDPSTLFANMTFYLSRETPRQPIEFILRAFGCKRIGWDSVLGDGAFTTNENDPSITHQIVDRPPIQVRAEKDADTENVEDNQTAQKLGVNGRVPGRVYVQPQWVWDCINDEEVKSPDLYAPGAQLPPHLSPFVKPEAGRYDPTIPLADQQPEAEALESDEEEAEAEGSAMDEDETTFNDFSANEEEDEDEDEDEDEVTDDERQMELEAELRGENVHSKAKASATPREKARQQARKEFARKAKEEAEDKERAMGMMSKKKRKLYEQMVYTNTKKSTEDQKLRSKRRKMEKEQQKKKTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIE1</accession>
    <name>A0ABR3ZIE1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Protein ref(2)P</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_000902</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02340">
        <property type="entry name" value="ZZ_NBR1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028846">
        <property type="entry name" value="Recoverin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055">
        <property type="entry name" value="CALCIUM BINDING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055:SF187">
        <property type="entry name" value="EF HAND DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G07310)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00569">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01357">
        <property type="entry name" value="ZF_ZZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ZZ-type" evidence="8">
        <location>
            <begin position="166"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="338"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="46"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="537"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="636"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="737"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="886"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="116"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="543"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="577"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="636"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="669"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="752"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="772"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="792"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="807"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="829"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="894"/>
            <end position="907"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1900436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="961" mass="108477" checksum="B6DF6CFD8D018CF3" modified="2025-10-08" version="1">MWLNMPTATGITRSRIAFFAAISALSLASLGYYVYQLRAAYPPSRTTRLHRRNATRHARRSRQRRTRISEEDEPETASIAASEHGNDDNDNDGYSNSNTRDRHSQRDTPYHSNSDSESEEEGSAARGDEEDAHEGSAEYSSRAGHNIVGLLFRVSEDNARRNAYVHRGCQCNSCSTVPIRGIRYRCVNCADFDLCEACESQSLHNKNHVFLKIKVPVPPAGLRSIQPVLYTGDPDNCVRILPKAIINKLCRETGFERSTLEAHWERWTFMANTEWREDPDDLCLAMDRKTFDRCIAHNGTSRHLPPNLVHDRMFAFFDQNGDGLISFREYLHGLAYRSKKERLRKVFDGYDIDGDGYVDRKDFLRMFRAYFTIFKQIHKDILDGLDTQAMSLLDTQQLITSRTPLSSFFGRDESVPRADLDDSRIAGKTLQPNGSVSLPSPLSSVVQPSEQEIASRAEVLSAVFTINAAHEPTRADSIMQNILPNALLSPPNDINALLNLITNVSNNRGPISRSNNPMSFASSSRAGHTVLDEVLDSIDDDSATNSGDARYNSPSTEDLNNMPESNQGRDISSQPPHGHELTDGERKLQRRVRRRMFDRWKRRQFYLDVEEGGQAPSGWDSDEDIVEAISVMANPDPEHVSFNTRRDSTRSRSSSKVRFADQDDEFETRSNASTSSRSIPERWGGFDIPEAERDLGKEILYLTAQEAYNEILDVFFKEKEDLAVKAAETREFRHQHRDLMDTLLPHGSLKSSSRDHARDPRNSAASHRQKPETTSNENDPTMGSAQHESDESGAASASDGIDQSSQLTSPTSDSAPISHTKSSGNSHQNNDNDNGSASDSDDAITEILKEMVEIYRDPTMPQFRPNNTDTVHETPAVTTTALSLIDQDAPKPLSSERKTRSSRNKDSMLRKLRKYNDAEVEAVERRGFGKLSFAEFEKIYREQEAQYRMDYLETWIDIYMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIN1</accession>
    <name>A0ABR3ZIN1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Proteasome-interacting protein cic1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">CIC1</name>
        <name evidence="2" type="ORF">Cpir12675_001119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_uL1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_uL1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="Ribosomal protein L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="395" mass="42866" checksum="169AC87BD40F4092" modified="2025-10-08" version="1">MAPSKTVAVPAQTSITSLLDASQTLKASRTLLSHIKKTAAEKSEAAPKKSLLDDPEAETPSSISETPVWLVLTTKRHISDTSRLQPSKISLPYSLNTSEWSTICLITADPQRAYKDIVASGDFPPELAKRITRIISLSKLKVKYSQYEAQRKLFSEHEIFLGDDRIINRLPKILGKTFYKSTAKRPIPVQLQSKVQRGPDGKRGKRVKTEGNINAGTPKDIAAEIEKALSSALVNLSPSANTAIRVGYANWSADKVVANVTAVVNSLVEKFVPQKWNNVRSLMIKGPETASLPIYQTQELWLEGKDVVADESEEAKALKAAQTANISKKRKAITGASESTEATGKADKEPVTKKAKAAAAAAVAVENETKALNSKIADRKTKLKKAKAKAVKAMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIP6</accession>
    <name>A0ABR3ZIP6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_001135</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050745">
        <property type="entry name" value="Multifunctional_regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189:SF50">
        <property type="entry name" value="ANKYRIN REPEAT AND SOCS BOX PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189">
        <property type="entry name" value="MYOTROPHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1420"/>
            <end position="1452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1867" mass="204801" checksum="7D2B78DE3E34C342" modified="2025-10-08" version="1">MTLAELTLEERNLRIQQLRIAWNIDLASSQRSSESHELKIAPSFRTPDDEVKAEALLRRRQLETPIGIKKSSSLKRAFTNRKKGWQPIELLDALDVHVCDGGSPGVAEVLLGRLAQLGASINEQPTERRSSFIGRRRSEGFGYAERTRVVENAVKSRNVDMLRALLPYADSVALDSAIVTATLLCEEPMVEILISKGADPFRDLEGQSAFLELCDMGGQENLVRLLVSGAKGSHCLAIGMVKAVKSGCFVTVLQISQSMADCDYNCAEALRIAIENGRKDIALAIVTAKKPPQPAGLEAALDTLFEQSQVHPHEKLDMTELLLCAGARGDAASRALLHAASSQFVEMVRLLIRYGASVQYLDGAVIKEVVTKGHDNLLKTLLSSGLPLSPQLASDCVKLIPPHINPDCRYSLLTMLLRNGASGECLDEALVQAVLSGNDTIIDLLVKPEFPNKGSTTCPSGRQEVLNSHAIASVDYKNGEAIKAALAAGDISVISTLLSVGPSPETLAHTFTHTHRLPREARQEVVHCFIEAGVPANVIKNEFRREIEQHSGHRDDDIVAILLNYMSKEDFDITSAITAAIARQDRSLLATVVQHATNLEAAESIPKAMSITDEGMRREIITLLLVAGADAEKARIVAAVMTVLKSEPVDVKLLRLLLTRGHADMNELGGSPLLCALAHPDPLIFPLVLKNTTLAPATILAAISKLLSQPDSKEKISNLTALLRLSVPKADLGDLLADEVHSFIQTPKADRNIRAIQAMVQAGADVNGPEGLALARAVSATHMPLTEMLLAENPTPETMAYAFRQAINLLDPIDRLKFAERLLKSSILPTEVDQALIYSIKKYPEDLDLLGLLMEKADMSSGEALNLAISHRKLDIVKLLLGNKHSDVVLIEAFKLSLACTEKEDRQRLTETFLNADIPKQIVRDSLSTAAGQGDLELVNTLVTYGGKVHDIDRQSMIQAVRSESPEMLKMLLGEENGAISPETLNAAFHTATQISDLEKRSLVFEILLLQGGIENDLASAELLFAVEGGVAGVKLLTVLLSCGADPNFRNAEAICVAAQNECFEGLQLLLARENPNTQQIKPTSISLAIALKASWKLQRDKRLKVAEWLFDAGLELCVEIHIALQKTLVLKAGEELDVEMMKLLLSKRASPTYDGCKSLIRAACIPSPSILGLLLEHSDISDKEASAAFTVSFPPDAASRWLSEDGYQCAKLLIEKGASGDGLSIAFVVVLEARNSSNSSLVDKFADFLIDNGADINYSHSRALRMAVSRGNIQWVQKLLDGQPSSSSLSAALGHVFDGNLDENEATLILHMILSYNYEGVTIDTGVPLQGDQIPVLARALLQFPRSTKMMTILLEAGYYYDPMLACFVGSQDKMSEREQEQVTLLVWAIIQPEKRISSAVIETLIKAGAAVNFQTPRMQMTPLMLAIREKRPDVVKALVLNGADVDLVDAYDTSALLMAASLRDSLATDVMSTLLLVGPAKNDGSLHSAARQLNLATVELLLKHHHDADFPSLAHDGRSALAELCLHACDEGSPPLTNARQLEMRKTMEILIKHGSDLEVKSLNESSGANAGSGKTLYHLAMESASPWLTLQALLKAGLWKLVNEPFTHFVINNMTYSLTMYVRHVRPWDEFSDSLLTLLRNNRTVDVFYANEGPQPDNVIGLPNELVIEERDRIARQKQESLMREKHLQHINYQRELAAIDSQLWKDKAAMEDVHRTKVHRDEIAASRERRMTEVEHFQAMLDAKTAAQRSERAHLTALDRASALRLAREIEADETRHRKLLDFESHLATERAANQRAVSQIELERQQHIARYEREASERDLTRIQAHKQLIQDQSALAMQLGNTRSMAQIPARKAVGYVTDIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ68</accession>
    <name>A0ABR3ZJ68_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase M12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_000774</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF850">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045399050" description="Peptidase M12A domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12A" evidence="3">
        <location>
            <begin position="105"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="421"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="487"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="497"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="554" mass="62834" checksum="CF7F7B5449B5F962" modified="2025-10-08" version="1">MLLTHAIAVAAAISNAAAFPSDDWPLDPSDFAETVTMKYILNPFGLNNQPSYTAYRRVAYFEYDGRAIINGDEIYDSMSNMKAAIVKGKHESRSLSVEKGRHSLWPNGKIYFFWYDKESERARGRMLNDAIEIWQSKLPWLKFIKRGYRKGSWGLGPLTIKAVPGKLSASSIGHSTRPEGNYLLLGETDDLRDYVHQIGHVLGLTHEHQRSDRNENFDLFCDRIKPTTAVDADGQVAGYRPANCDPETCTGYGCNFTPLDSTDLGLLAEGPYDFNSVMQISPSAYKDPAVDGNPLVPKLGIELPKYTSMFPSVADAMRVCRLHPTSCKSMRGNGIIEDEDQYNDEDYIDDDIEDGIQHGGCGYTCTNEKQKSSYEEYTDQSWGTSKEGSYTDEGDETWVMKEVKEGEKDELVEWGENEIWEEEGEWDGEEEEWEEEWEEEVGEWEEKVEEWEEKVEEWEEEDEGEGQHQQQGEEEEWEEMKGEGEEQQPQQKQQQPEGKKEEEEERHIECFDQCSSDSKQSLAQLSAPLASYPAAEMSSSSVTPVGLGDGEGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJI2</accession>
    <name>A0ABR3ZJI2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Endoplasmic reticulum-Golgi intermediate compartment protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ERV46</name>
        <name evidence="10" type="ORF">Cpir12675_001287</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Plays a role in transport between endoplasmic reticulum and Golgi.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Endoplasmic reticulum membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Endoplasmic reticulum-Golgi intermediate compartment membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Golgi apparatus membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ERGIC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000019">
        <property type="protein sequence ID" value="KAL1899704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045888">
        <property type="entry name" value="Erv"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012936">
        <property type="entry name" value="Erv_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039542">
        <property type="entry name" value="Erv_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984:SF25">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07970">
        <property type="entry name" value="COPIIcoated_ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13850">
        <property type="entry name" value="ERGIC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="387"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter N-terminal" evidence="9">
        <location>
            <begin position="8"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter C-terminal" evidence="8">
        <location>
            <begin position="142"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU369013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1899704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="428" mass="47279" checksum="826C83345EDF6781" modified="2025-10-08" version="1">MAAKSRFTKLDAFAKTVDEARIRTTSGGIVTIVSLIVVLYLSLGEWLDYRRVTVHPELIVDKGRAERMEIFLNITFPHMPCELLTLDLMDVSGEQQHSVAHGINKVRLASEADGGRVIDIEALNLHKDDDAKHLDPNYCGGCYGANPLPHAIKAGCCNTCDEVREAYTQAGWAFGDGSGVEQCTREHYKERLEEQRHEGCRVEGGLHVNKVIGNFHLAPGRSFSNGNMHVHDLKQYMDSNEQDGGNHDFTHTVHALRFGPRLPESITNERLDNVNPLDNSNQRAEGPNWNFMYFVKIVPTSYVPLGWESKGHMVNSDQDGFASGSSGGVIETHQYSVTSHKRSLEGGTDAAEGHEERQHARGGIPGVFFSYDISPMKVINREERAKTFTGFLAGLCSIIGGTLTVAAAVDRGLFEGASRIKKLRSKDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJJ0</accession>
    <name>A0ABR3ZJJ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_001013</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000014">
        <property type="protein sequence ID" value="KAL1900329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1900329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="116" mass="12868" checksum="E6C317F5F4CA4C0F" modified="2025-10-08" version="1">MAPSTPRPVTVQWLAMMRQSMDHYVQYLIAETLSTLHEAFSGQSYITPAQRSLQPCCNAVSVVLIPVRTKSAFMTFGVVSSILLVLCSSKMHAGAIFSQARLLTSLYQKDTQKDIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK48</accession>
    <name>A0ABR3ZK48_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Squalene synthase</fullName>
            <shortName evidence="10">SQS</shortName>
            <shortName evidence="10">SS</shortName>
            <ecNumber evidence="3 10">2.5.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ERG9</name>
        <name evidence="11" type="ORF">Cpir12675_000897</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>2 (2E,6E)-farnesyl diphosphate + NADH + H(+) = squalene + 2 diphosphate + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:32299"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15440"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.21"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>2 (2E,6E)-farnesyl diphosphate + NADPH + H(+) = squalene + 2 diphosphate + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:32295"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15440"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl diphosphate: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the phytoene/squalene synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.21" evidence="3 10"/>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051996">
        <property type="term" value="F:squalene synthase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00683">
        <property type="entry name" value="Trans_IPPS_HH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006449">
        <property type="entry name" value="Squal_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019845">
        <property type="entry name" value="Squalene/phytoene_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044844">
        <property type="entry name" value="Trans_IPPS_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033904">
        <property type="entry name" value="Trans_IPPS_HH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01559">
        <property type="entry name" value="squal_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11626">
        <property type="entry name" value="FARNESYL-DIPHOSPHATE FARNESYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11626:SF2">
        <property type="entry name" value="SQUALENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01018">
        <property type="entry name" value="Squalene/Phytoene_Synthase_Lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01044">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01045">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="7" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="8" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="5 10 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="399"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1900431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="460" mass="52749" checksum="B592E1184E41438C" modified="2025-10-08" version="1">MGKLYYLFHPNQLRSIIQWKLWHDPVHRRDPSKESPTLQSCFKFLDLTSRSFAAVIKELNPELLVPVALFYLILRGLDTVEDDMTIPIATKEPILRTFWQILEKDGWTFSGNGPNEKDRELLVHFHDIIHEYKLVKPEYREIITDITKKMGNGMADYALNAEHNINGVATIPEYEKYCHYVAGLVGEGLTRLFVTADFANRVLLDRPQLTESMGQFLQKTNIIRDVREDFDDKRRFWPKEIWGKHFEKWDDLFDPKNLEKAIWVSSEMVLNALGNLEDCLYYMSAVKDQSVFNFVAIPQSMAIATLELVFRNPDIFNRNIKISKGDACQLMTESTQDLRTLYDAFRRYVRKIHHKNDPRDPCYVKISTACARIEQVIETIFPSQTLKSTKAASSSNDGLFFMVTVVGMTVVLGLIMVAFAFGFSIILGKYFPDTTASLHDVVSSATKAVTSTASAIKEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK88</accession>
    <name>A0ABR3ZK88_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA repair protein rad14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RAD14</name>
        <name evidence="6" type="ORF">Cpir12675_001183</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000017">
        <property type="protein sequence ID" value="KAL1899959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21077">
        <property type="entry name" value="DBD_Rad14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.530.10">
        <property type="entry name" value="XPA C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000465">
        <property type="entry name" value="XPA/RAD14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022656">
        <property type="entry name" value="XPA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037129">
        <property type="entry name" value="XPA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00598">
        <property type="entry name" value="rad14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10142">
        <property type="entry name" value="DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10142:SF0">
        <property type="entry name" value="DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05181">
        <property type="entry name" value="XPA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="Putative DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="XPA C-terminal" evidence="5">
        <location>
            <begin position="225"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="25"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="378" mass="43012" checksum="87ECEF95FCB6A76B" modified="2025-10-08" version="1">MEGSTRRQTRLQSSVTPEIAKRIEENQKRAKALQDRKNAGTQLRKTTASSKARPISPATTAGSPTTPAPLTSIAGTKRPRSVSGSLNPLDSNRDGTRQTPDGAPLRPAKKFAKYVEYNMSTMSDNKGGFLTTEDDPYNAALQPRVRPGDDTSGKPKNMTAREWERLQIIRDLERRKAGPFEPGISVIEEDAKRCRECDSREIDFVWEDVFKVCVCSPCKDKFPEKYSLLTKTECREDYLLTDEELKDADLLPHLNKPNPHKTHWHDMMLFLRFQVEDYAISQKWGSAEALDAEFEKREEQKKRRKEAKFKEKLRELKRKTRTDAFRRQVEGLAGPANFGDSLSGGKHVHTWGRTVENSDGMTVKKCLECGMEVEELEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKJ3</accession>
    <name>A0ABR3ZKJ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_000484</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06137">
        <property type="entry name" value="DEDDh_RNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047021">
        <property type="entry name" value="REXO1/3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801:SF45">
        <property type="entry name" value="RNA EXONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801">
        <property type="entry name" value="RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exonuclease" evidence="7">
        <location>
            <begin position="398"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="182"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="307"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="538"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="48"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="92"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="618" mass="69336" checksum="989B502A7CEED485" modified="2025-10-08" version="1">MSPTNYSMVSGGQASADDKSTVYVNPKSAGRGRNRKRGKGQARYPVNSSESSSIGGDSSTRGSHDKTHVTDGEMTQPSQSFQHGPSLPLDATQGQLHPQAQTWSQRIHKMGTKQETARPYAQQIGAYDANTTASPAVDDLRLKTLSLVSSQDRSLEFCTEPPSMISSIRTIPKSYAHSLPNCSTAPSPAFRTKTSHPLSEQETKPPQMPQPHKRLNSEKMVSILRNNEPVMQEDGTILYRLCSSGIASDPSYVSMMESLCHSAKVLMDKGYPFRQLTIEELERKNNRCGRCLKSTTARRVRNRNCGRFQGQPKETKENFQDDGHEELAKDKEASEEKPKCLYHSGTMANKTYTCCGGNQFTKPCMRAKNHEAKEVEISVLQGNWKMYETSHETRDPRPCVAIDCEMGVGIDGDSELIRITAIDYYSSEVLLDRLVFPDNPLLHPNTRFSGVSFVDLKTARQNGTAILGRDAARDALLNFVNRDTILVGHSVNNDLVSLRWIHYRIVDTYLLDFYEDKRQRDIKVREFAAYESMAIEHMLDKSKPRPPTPTKPDDLGHQPSRSLKTLSKQRLNRVIQGGAHDSLEDTLASRDLLNWWILNKVQPSLQESSPKGKGWCNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLN2</accession>
    <name>A0ABR3ZLN2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000761</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="442"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="735"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="171"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="580"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="746"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="769"/>
            <end position="779"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="824" mass="90998" checksum="65BDDC1B51700B99" modified="2025-10-08" version="1">MTPMALSGATSDDPDAFTILYTSPSPSQLETPLSSVPVTDRPWFVATVVLSAVAVLCAVVSLSFMLYRRRRRHQPPLSVLSPGPPPIPPHRQLPLPVPLPHPIAPIVYHTSHEKPVLTSAPTCPSAVFLKRSSTQSFAAIGDHRASSHYNPRDSGSHSYSHSQRHSRSRNLSRNLSRTLSRNLSRTRAMTPEQLILEQENQRQLALRMARQEATAQCTASSSISALPAAAVPPYTPSQFSARDSSIPESESIMYSVSMPPPIHENDDATVQSSPPPAFSSAEPGRFMCEQEIAPHLRDEWGSCKPSHAWYIKQHNQHACQEQLHNFQQQAWPQDEHLYRRQFQRQNQQQNIMQQVYIAEDEVYSTDSDDDSRSISSQISLRSEWKAFEAAAQRNQSGVHPVIKNDSESSSPNPKSNHRPEPLLNTSASAALLSFTMETPLPSPSAFEHSNHCQSLIPPPLLPRRSSRRRRTRSMDATGYEHTVPRRSNGTPVLTLTVPAPVVLRKAVSTSEFLKHHRQASSMASSHLEYGWPALDFDWLPFQKKDNHQHTEEEDEEVASLSCISPLTTIPPKNQIAIARPPSRSSSYSDGFSDSYSSDSSSDSINSPSNNLSNSSSNHNLPSPSSAPSSAVTAPEPRSRWSDEIMSNRLDLPIDRSQSMDTSSYQAYRAKRAAQAKRLPPGGWQLQISTLDITGACPRPSIVAEDEVVESFPVSPAPLQHSPVSNQLFQAQSAVTTSHRSSRRSILRSATSQTLSDSSSPTQTPSMKPVAKEHHEEVANRRRQSSTLTSSYGVSAPQRWHSSNDSELICSSRLDGPLGDLMPGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLT5</accession>
    <name>A0ABR3ZLT5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MICOS complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_000363</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019166">
        <property type="entry name" value="MIC26/MIC27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033181">
        <property type="entry name" value="Mic26_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28268">
        <property type="entry name" value="MICOS SUBUNIT MIC26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28268:SF1">
        <property type="entry name" value="MICOS SUBUNIT MIC26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09769">
        <property type="entry name" value="ApoO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="1" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045759434" description="MICOS complex subunit" evidence="3">
        <location>
            <begin position="34"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="73"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="73"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="265" mass="28304" checksum="8C709851312258D3" modified="2025-10-08" version="1">MAARVFMRQSAVAPLAASILLAGFALRPEAAYAETSQELVSSRKPIYDDAPVSATAAATSKPAAVAPTAATPTKSFFSSSSSPSTSRANRPARGPSPTDRLAMKIGKVRLLLHGYVVSAEDAVNNTMAKAFSLEQSFTGTIASLAPAKETGEKILPGAVYVLVAAMSGSIVARNRNIVLRTLAPLALGIGASWTFLPVTSRNVSDLAWKYEQRFPSVAEGHIKMRESILRGIHFAKVHKQFGLQYVDDTVTNVRESVEDWVKQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLW8</accession>
    <name>A0ABR3ZLW8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proteasome assembly chaperone 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_000392</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018788">
        <property type="entry name" value="Proteasome_assmbl_chp_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053720">
        <property type="entry name" value="Psm_Assembly_Chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31051">
        <property type="entry name" value="PROTEASOME ASSEMBLY CHAPERONE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31051:SF1">
        <property type="entry name" value="PROTEASOME ASSEMBLY CHAPERONE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1901701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="147" mass="15663" checksum="38A2FDBB58CD6990" modified="2025-10-08" version="1">MEVSALISTPYPIQAHAAVATVNGMPTEATSRVFTDKVMITLSQEGRLAQWIHVPIRATPASMAGLTANHPRHDMLPASHITPTTLFGGGGSYREATGHLLASQIANYISLKSPTDERTLVLGLGLKQLEATPTGLLDVLELVQQVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLY5</accession>
    <name>A0ABR3ZLY5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zinc transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">zrg17</name>
        <name evidence="9" type="ORF">Cpir12675_000235</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Functions as a zinc transporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Endoplasmic reticulum membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045316">
        <property type="entry name" value="Msc2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45755">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45755:SF5">
        <property type="entry name" value="ZINC TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="8">
        <location>
            <begin position="102"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU369017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="438" mass="47435" checksum="9263EDEBD584EA15" modified="2025-10-08" version="1">MADNNSASDSPQSSSLAGSDLPAAAVASPFNFQPQELSTSPVRANIGQRRGHRYKHSSVSAQHQIFQEPPQRPPPVLPASLPVPTFKEARDSMSHEQRIRALWCLCHLAVAVFVFFESHGSLAMMALSHLVFFDAGSAAICVAVDVLGNFEVWRRSSIRHPFGLERAEVLAGFAMSVFLLFGGFDLVSHNVKHFLSDVAGDGLSAGLGLDGDRGHGQGHNHGGHGGHSHPRVSTGAMDWASLAAIISTLISAYGLRNHARIAKAMRVSYLSSLPSLIANPFHFLAFCFSALLLLMPVLSIKYYSWMDHGICAAIALAMFALGFRLAIAQGLMLLMSYGGTSTGFFSSENSVPLVVREIESEPEVAKVEDAQFCQVHYGLGLASLKLRIRRSVDDQALGKLRTRISNLVQNRLGEGYGQGSSLRWEVTLQTTVDMSLNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM69</accession>
    <name>A0ABR3ZM69_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_000264</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="377"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="377"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="343"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="445"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="445"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="484"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="510"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="619" mass="69223" checksum="9720B1E46552C059" modified="2025-10-08" version="1">MSVSESLKFCVQRQPTNEAKPPYFVPLIPLDILPPPYMSVPGFPRYIPADDVGIGPNKWTSVGLVPLEDVSAPLSCEGVDNKVGNGYGLGIQQEYRELYQAAAERRRSAYWQRRKQVIDNRDDALSLSSVHTQDDLEYDLKDSKASPSLSSLPSSHEELSNHYAISPVLDSKNLGFSNNTSESPDDATPMFFPIKNTNKWDHGEGGDGYNGGYSDDELLTLSRLSRQSQLHDKRRQSGWKPELPEILVPTTIGLQLSSANSVASDSYVSASIEGHVGTEGGVPLCPHTRLQPLSLEATAWVSPRVNNENHAPSPSRVRLDSSMHYTETKLDFFSSMHAKSRSPARWQPSLTPALAEDTSLAQTSSKKEKKKKKKKKKKKAGYCRSWCRTGDCSYGLKCIYRHDMPKSEADFQTIRLEEAPAWYFLMNNLPRTGNQGCEGYIADRGQQQQEQHGQYSADSPVRDVHLPHPYPRAKNDKTKSKQFNDSTTHTNTRSNSSIDNDDSANGSQRQRQRQRQGQRQKPKQKQNKTSDHAERAKIELDAILEQLTSKSRAEEDQAEENKKQKQRYVELAAKEKNTEASTLINKVVSGGVATSSLVRFGNGSSGRQMESYLDVLIEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM80</accession>
    <name>A0ABR3ZM80_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Vacuolar protein-sorting-associated protein 36</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">ESCRT-II complex subunit VPS36</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">VPS36</name>
        <name evidence="10" type="ORF">Cpir12675_000671</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the endosomal sorting complex required for transport II (ESCRT-II).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the VPS36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000008">
        <property type="protein sequence ID" value="KAL1901181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021648">
        <property type="entry name" value="GLUE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040608">
        <property type="entry name" value="Snf8/Vps36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037855">
        <property type="entry name" value="Vps36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031558">
        <property type="entry name" value="Vps36-NZF-N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13128">
        <property type="entry name" value="VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13128:SF12">
        <property type="entry name" value="VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04157">
        <property type="entry name" value="EAP30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16988">
        <property type="entry name" value="Vps36-NZF-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11605">
        <property type="entry name" value="Vps36_ESCRT-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51495">
        <property type="entry name" value="GLUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0967">Endosome</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GLUE N-terminal" evidence="9">
        <location>
            <begin position="6"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="94"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="314"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="325"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1901181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="613" mass="67282" checksum="443DE3965DF17BA3" modified="2025-10-08" version="1">MFLKQLDLTTALRPAYLTDEVLLFVQDNVGLYEGKYKLPNQQNGQVYLTSHRICYVDKASPRMFSVALDLRDIERYELYNGFLKSSPKITLFPKPPSRMSTLQNRSLGRSSYNRPTHQSSPLTKPRSESAASLNTSATWVCTICSFSNPVPTNFDPTLANEHTPLPPCLACGIKPTLGHVLKAAIANATKHANTYSTPTATFTYSASTAKITTATAPTATVGDNTDIDATFQCPRCTFANHPSLMACEICGAPLLSQNIPQELDPMRTESPGPTLPSKATLDAHEPVKISFRGGGEKVFYERLKGSITQRKWLLNGAPPIPNKAQSNEGGPTSSSSSSNEQSRPTVKSVGIAALEQKGVDMRKNNEIMIGNAFEDLEALMASAKEIVDLAERFSRKVNRNSTEATSVATQLGLVTTKDIAGTSESLYLSELARTVAEFLTDDSRGVLKKAGGVISLVDLWAMFNRARGGVELVSPTDFEMAARLFHKLKLPVRLRTFKSGVLVVQGKDRTDDSIIRALLEWLDDLHQFPPDKEVSWDWHEFGRGVTAQDAAERFGWSIGVAEEELDMAEQKGVLCREESIEGLKYWKNYIGSLQAPASEAEQIEQALKLIGII</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN09</accession>
    <name>A0ABR3ZN09_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fimbrin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">fim1</name>
        <name evidence="6" type="ORF">Cpir12675_000187</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21294">
        <property type="entry name" value="CH_FIMB_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21300">
        <property type="entry name" value="CH_FIMB_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21303">
        <property type="entry name" value="CH_FIMB_rpt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001589">
        <property type="entry name" value="Actinin_actin-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039959">
        <property type="entry name" value="Fimbrin/Plastin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19961:SF18">
        <property type="entry name" value="FI19014P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19961">
        <property type="entry name" value="FIMBRIN/PLASTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00019">
        <property type="entry name" value="ACTININ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00020">
        <property type="entry name" value="ACTININ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="5">
        <location>
            <begin position="145"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="5">
        <location>
            <begin position="294"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="5">
        <location>
            <begin position="419"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="5">
        <location>
            <begin position="544"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="117"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="654" mass="73302" checksum="BFEA810ECC7BD669" modified="2025-10-08" version="1">MNVIRLQKKYPQFQQPEIFALSDAFRKLDVDDKGYIDESTAIKATQNSERQPYDVVRQALKEVDLDSSRRVELEDYVGLIAKLRESSPAQQRMSTGNHPAPTSPITTGIVAQLTGSKIGHRSRPSGSGKILVHGSNTNTTHTINEDERTEFTRHINAVLAGDADIGHLLPFPTDTFEMFDLCKDGLVLAKLINDSVPDTIDERVLNIPGRKIKTLNAFHMTENNNIVIESAKGIGCSVVNIGSGDIIEVREHLILGLIWQIIRRGLLGKIDIKLHPELYRLLEDDETLEQFLRLSPEKILLRWFNYQLKAAGWQRKVTNFSTDVKDGENYTVLLAQIGADYGCDRSPLQTRDTLQRAEQVLQNADRLGCRKFLTPKSLVAGNPKLNLAFVANLFNTHPCLDPITEEEKLQVEDFDAEGEREARVFTLWLNSLDVQPSIQSFFDDLRDGSILLQAYDKIIPGQINWRHVNKAPAHGGEMIRFKAVENTNYAIELGKQAGFSLVGIQGADITDGQRTLTLGLVWQLMRRNITVTLSDLARRLGKREITDAEMVRWANDMSRKGGKTSSIRSFKDPALSSGVFLLDVLNGMKSSYVDYDLVTPGRTDDDAYLNAKLSISIARKMGATIWLVPEDICQVRSRLVTTFIGSLMATHEKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN86</accession>
    <name>A0ABR3ZN86_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_000312</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="244"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="121"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="373"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="458"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="376"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="487"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="507" mass="56498" checksum="7B9705C980B5D3BB" modified="2025-10-08" version="1">MSLADSAAGIAPVASTLFVRAADKDRAEAVATVIPCIALCMTITCLVAALRFFSVRQPLRNWGWEHGLLLVSLVFAFVAMGASISMKVNGLGYHANVYQKKLTVYTKMLWLDGLAHILSPRVLCKLILGFLVLTHLWIVVSIFTTCVPLSSLWDVSPFGVKAGVYCHPKAVFWLNYGLHVGTDFLIFALPIPLMFYVAVPLVQHIALFVMPIAGFAICAISAVRTATLVSNIHLDDITYTTVSYVNLTMIEIGLTISWASLLAVRYIYDPLSETQDQSPAIDAAFMREQLDIFPHNLRISTQNVPGEHKIPLDLQPLPPALHRSLQSQETMVWGEDITEYTRRHHHRLHLDSVPSPYYHQSLYGMRLTESQVAITQVQSRPQSSQSRAHSRAHSREDSQPQSRRNSDMSGFLPIFAPADTADDDGMPGRGSQDKDGRRLSYKILNIQRSTTPSSISLRFATAPKPKPTSKWRRSHVPVDDDEGNEEWGPHPGDRRSLTSPMFVPHLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNB0</accession>
    <name>A0ABR3ZNB0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">rRNA (Cytosine-C5-)-methyltransferase nop2</fullName>
            <ecNumber evidence="12">2.1.1.310</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">NOP2</name>
        <name evidence="12" type="ORF">Cpir12675_000078</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.310" evidence="12"/>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1170">
        <property type="entry name" value="Sun protein, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011023">
        <property type="entry name" value="Nop2p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023273">
        <property type="entry name" value="RCMT_NOP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018314">
        <property type="entry name" value="RsmB/NOL1/NOP2-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00446">
        <property type="entry name" value="nop2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807:SF30">
        <property type="entry name" value="28S RRNA (CYTOSINE(4447)-C(5))-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02012">
        <property type="entry name" value="RCMTNOP2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01153">
        <property type="entry name" value="NOL1_NOP2_SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 12" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 9 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="11">
        <location>
            <begin position="327"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="225"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="623"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="679"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="51"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="116"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="156"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="240"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="625"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="697"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="736"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="751"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="544"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="419"/>
            <end position="425"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="443"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="470"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="487"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1902178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="762" mass="84453" checksum="6EE0E6408E70BEF8" modified="2025-10-08" version="1">MGVGRRMGKKQGIPEALSEGHFAKLKRKAGLPVDEVSDEPEKKRRRGVKRAAVEKAKQDKEEERVSRTAKKALEAKSKRAAAAALTAAAFPTPKKASIPAKAKKAKKTKVSLAPSSDEEDEEEYENMADEFPDADVNDSDDGEEPLKLRDNFLGSDLDDDDDGDNDVYDSDEDQTRGGKMVFSEDEDESEGEERLTRANIAAMSRKIDEERAREEEAAEAEMRDMQTNIDGDDRPKILDNDEDDLDGEDPLYAKPKALLAPDLQLLRTRITETIRVLDSFSQLAEPGRSRSEYTAQLIKDMCAYYGYSQFLCEKLFALFPPREAFAFFEANESGRPVVIRTNTLRTHRRDLAQALINRGVTLEPVGKWSKVGLQIFESNVPLGATPEYLAGHYILQAASSFLPCVSLDPQENERVLDMAAAPGGKTSYLAAMMKNTGFVLANDPNKSRAKALIGNVHRLGCRNVVVCNHDARDFPKPIGGFDRVLLDAPCSGTGVISKDPSVKTNKTERDFQTLPHTQKQLLLAAIDSVNHASKTGGYIVYSTCSVTIEENEQVVQYALSRRPNVRLVDSGLTFGKEGFTSIGGKTFDPSLKLTRRYYPHTYNVDGFYVAKFQKFAATPGKAMRSDASSSAAPTSDDDHAPVVDDDGLGAQMDKENEEVAANDFGGFDDEEDNELIEKARRNSMRRRGFDPRASVTKKKDEKKTEEKTEEKTKEMKASEKTEKKKADKANKKEENINISKPNVAQQEAKATKKSKKAKKTAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNN4</accession>
    <name>A0ABR3ZNN4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_000135</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112:SF22">
        <property type="entry name" value="MITOCHONDRIAL TRANSCRIPTION FACTOR A, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="4">
        <location>
            <begin position="227"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="2">
        <location>
            <begin position="227"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="53"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="53"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="68"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1902030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="293" mass="31960" checksum="01038BA5F4B0EE62" modified="2025-10-08" version="1">MLNIIARRVAGRRLVALPIRASIRPSAAIVSRVPFSTSNASYAVAKKAVAPKKTAAATTKKTTAAKKPAAKKPAAKKKPAAKKKPAAKKKPAAAKKAPLTPEQKTRKRIAALRAEAQLKAESEGYQPQHAYGLYVAEAIRGQDLKKQNITIVEALKSAIDGYKALSSSELESYKARAQANKAANQAITEKWIKSKTPTEIIAINKARRSLARLTEKRILQLDDKRIPKRPKTAFFIFAEEKRLSGAMNNLSLIEGAVQSGVAWKALSGAEKQTYTDRYNKEKTAYDAQMNKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPE7</accession>
    <name>A0ABR3ZPE7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AA1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045910204" description="AA1-like domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="159" mass="17018" checksum="ADCA6E49ECACA6A2" modified="2025-10-08" version="1">MLPKVFFFVPAILASAVPRQESCASDRMPTKFVIDNLSGTSNDTGASFIDLTFTYTPFSSSGVLSPPVTCSYDASTEPVKIPGRSNRWACKDPLVQFLYSSGRLTMVQKTCIQNGSPTIEASGSVHPTLGCTRSFPTHRCFNAQVNGTFVSLAPAPPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPH7</accession>
    <name>A0ABR3ZPH7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="261" mass="28479" checksum="F7A7528293B37551" modified="2025-10-08" version="1">MSSITQPSQSLPQRTKTFDFLQNLRANAISQVIPGLPSPTQNTTSNTNNTETSSIIPRSTRFSGTIEDLRKSITAFSIRSSDSESDHDYYPSRGGSRSRWSSVSGSLSLSGGPTPSVGSASVSGAHTPSVLSHEEAAVLRTRNKAAVTAAARRKYDARCRKWALERQLRDRYICECEKARTERRHEMARTNPGFQAAVEQASSTLLVQEMFLKSLAAKANKLVEGAGMPCRNGVEAEDPPSPEDLQKAMKETSEAVMSLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPY2</accession>
    <name>A0ABR3ZPY2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DNA repair protein rhp57</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rhp57</name>
        <name evidence="9" type="ORF">Cpir12675_000056</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19491">
        <property type="entry name" value="XRCC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047348">
        <property type="entry name" value="XRCC3-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46487">
        <property type="entry name" value="DNA REPAIR PROTEIN XRCC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46487:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN XRCC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecA family profile 1" evidence="8">
        <location>
            <begin position="85"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="288"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="455" mass="48238" checksum="EDF2AE7D6C928DAB" modified="2025-10-08" version="1">MSDLSTVLPSFPTASFTKTLHSLDHHSITTSELLSRDVSTLAKLTSLPVLDLRRLAAAVAAALHASLRNTRTTSLAGLLAQPRCTSALISTLDDDLDASLGGGVLASRVTEIAGESGAGKTQLLLSLMLAVQMEAPRGLGRGALYITTEAPLATRRLAQMLATNPVLRAYNTMHRGLRAVGLDRIASASTPDLESQEHILAYQVPVMVERLDIGLIVIDSVAANYRVEYDRRGDALSARGAELSRLGQTLRGLAEKLDIAVVVANQVADRLGALTGVGLTQSQASSYGDVAASQASRDSTSTDDDAAGGLPEDVPWGLPTASAQAEPLPIAALELDHQHRFFTGWGDDPMILGNESMKTPALGLVWSTQVAMRIALILQPVYGQREPGDGQYGDGRERGDVTVRSSWRRFMKVVFAPHVKASSCGVSQAVEYEVVAAGLKAVVQREEEGEEGPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQF4</accession>
    <name>A0ABR3ZQF4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein DSF2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000252</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052945">
        <property type="entry name" value="Mitotic_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATORY FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="73"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="340" mass="35933" checksum="F4CA80DE91A892D6" modified="2025-10-08" version="1">MGIRDAIKKKDAVTVSDSSYAAAISRVNTGAEFTFIRSDTFGQSVVHPPGTPPATSSNGLLSPVSAEGGYSGGFRSRSRSNSAASARQKLSHRLHLSRNHSTSDNVPANLPAIETSQPDAETQWEKRATILAMGGSQPGSPNTTAPSPIHATNPFQWSAPQSNKELDSDIQRAIRLHEEGDLTNSTRIFAKLANPAGANNPLSQVLYGLALRHGWGCAPDPELAVSNLGLAAANAAAIEQRALEEGKKQGGPAKGELVLAIYELANCFRNGWGVGQDPVAAKQGMSFGGNIQSLANLWSGIKYFETAANLGDTDAMNEVAFCYLEGFGCRKDKTARARIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YCH8</accession>
    <name>A0ABR3YCH8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RHO4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rho4</name>
        <name evidence="5" type="ORF">Cpir12675_006927</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000428">
        <property type="protein sequence ID" value="KAL1886021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04132">
        <property type="entry name" value="Rho4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0488">Methylation</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="42"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="262"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1886021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="289" mass="32529" checksum="3AE9D618B13E9130" modified="2025-10-08" version="1">MTSYQQRNSHYSQPTESRYMESRHHSQHHSYNNSQDQRTRSSEGTVSTTMSSSSDRQSDNTQVTEGPAFSKKIVVVGDGGCGKTCLLISYSQGYFPEKYVPTVFENYITYPTHSESGKTVELALWDTAGQEEYDRLRPLSYPETDLIFVCFAIDCPNSLENVLDKWYPEVLHFCPYTPLVLVGLKSDLRFKKSCIEMLKTQGLTPVTQEQGMAVAKRMGAQYAECSSKEMTGVDEIFEQAINAVVANDRKTLEAELVKSGKSSKFPRSNTSSVPGVGQVKRKKRKCQFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YCL7</accession>
    <name>A0ABR3YCL7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Inosine triphosphate pyrophosphatase</fullName>
            <shortName evidence="8">ITPase</shortName>
            <shortName evidence="8">Inosine triphosphatase</shortName>
            <ecNumber evidence="8">3.6.1.66</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Non-canonical purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Non-standard purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Nucleoside-triphosphate diphosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Nucleoside-triphosphate pyrophosphatase</fullName>
            <shortName evidence="8">NTPase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">XTP/dITP diphosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">HAM1</name>
        <name evidence="10" type="ORF">Cpir12675_006873</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ITP + H2O = IMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>XTP + H2O = XMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28610"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:61314"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>dITP + H2O = dIMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28342"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61194"/>
            <dbReference type="ChEBI" id="CHEBI:61382"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 9">Belongs to the HAM1 NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.66" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000400">
        <property type="protein sequence ID" value="KAL1886066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:AMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00515">
        <property type="entry name" value="HAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03148">
        <property type="entry name" value="HAM1_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027502">
        <property type="entry name" value="ITPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002637">
        <property type="entry name" value="RdgB/HAM1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00042">
        <property type="entry name" value="RdgB/HAM1 family non-canonical purine NTP pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067:SF9">
        <property type="entry name" value="INOSINE TRIPHOSPHATE PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067">
        <property type="entry name" value="INOSINE TRIPHOSPHATE PYROPHOSPHATASE/HAM1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01725">
        <property type="entry name" value="Ham1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="ITPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="71"/>
            <end position="72"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="147"/>
            <end position="150"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="173"/>
            <end position="174"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1886066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="192" mass="21218" checksum="DA097A97797800A2" modified="2025-10-08" version="1">MPPRVLNFITGNANKLREVKLVLEPAGFEVTNQSIDLEEIQGTIEEVTTAKCRKAADIAFLKVGGPVLVEDTALCFNALKGLPGPYIKWFFQDLGFEGLNNLLVAYEDKSAQAVCTFGYSEGPGKEVILFQGRTDGKFVPARGPTIFGWDAGFEYEGRTYAEMEKAEKNAISHRGKALEKLQAWFKERSTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YD27</accession>
    <name>A0ABR3YD27_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chitin synthase export chaperone</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">CHS7</name>
        <name evidence="13" type="ORF">Cpir12675_006905</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CHS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000416">
        <property type="protein sequence ID" value="KAL1886038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022057">
        <property type="entry name" value="Chs7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35329">
        <property type="entry name" value="CHITIN SYNTHASE EXPORT CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35329:SF2">
        <property type="entry name" value="CHITIN SYNTHASE EXPORT CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12271">
        <property type="entry name" value="Chs7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="114"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="185"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="247"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="308"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1886038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="333" mass="37093" checksum="814AF3E91E818008" modified="2025-10-08" version="1">MPSFGDFTDICHQTPLPLCAAIGPKSATSTGVGIETTCFARNIELANTVIFQGGASAMHIVALTMTVIMIFHIRGKFTAVGRREILTFFYLYMLLTFASLIIDAGVVPPYSASYPWFAALQLGLSSATITALFINGFVGFQLYEDGTPLSVWLLRLCSLISFTVTFLVAIATFKSWSSLAPTKTTALFIVMVILNGVQLLIYVVMQVMLVAGTLQDRWPLGDIIFGVLFFAVGQVTMYVFSEDICDALSHYIDGLCIATICNLLAVMMIYKYWDSITREDLEFSVGTRMNNWEVKELLPEDERRQTIYHDDPYSPNGHDSYVPSPNARYSQRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YDY6</accession>
    <name>A0ABR3YDY6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase-like 1</fullName>
            <ecNumber evidence="2">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">cyp15</name>
        <name evidence="9" type="ORF">Cpir12675_006915</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000422">
        <property type="protein sequence ID" value="KAL1886027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01927">
        <property type="entry name" value="cyclophilin_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF4">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0697">Rotamase</keyword>
    <keyword evidence="6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="64"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="108"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="8">
        <location>
            <begin position="475"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1886027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="624" mass="69868" checksum="D0CC394C5891FECB" modified="2025-10-08" version="1">MSAVPQDEAATKRNHSQFTEDDSSSDDDMGPQMPSEGPKKKRRTLKYEKVYIASMPASNKYSKSLMHKDNLLFVTMTPITEFVITSSIDGVVKFWKKIAQGIEFVKEFKAHASEIRAVSVSDDGRSFATCGNDNTLKIFDVITFDLLAMIELGYTPQTLCWVHRKGASVPLLAISDESKPLIHIYDGRGVKNEPIHSISSLHRSPVELIAYNGVYDCAVSSDSKGMIEYWRPGDNFEKPNDVFEFKSSTDLFAFRKAKSTPVSLTMSPTGKQFAIFSLPDRKIRIFDFASGKLSRAYDESLQVLEDQQQIASGSDPLDTVEFGRRLAIEREIESDTFKNKSNIIFDESGHFIFYGSVAGIKVVNTFTNQIVKTYARDENFRPLNLAIYQGQPQKKVITTVEMGASSNPLLQESEIRDPILFATGINKVRFFMFTNETEISKSTRDVQNEKPIVINAKARAEKERKAQSGTGAVIHTSFGDIQIRLFPDAAPKAVENFVTHSRSGYYNNTIFHRVIEKFMIQCGDPLGDGTGGESIWGGEFEDEFSTLKHDRPFTVSMANAGPNTNGSQFFITTEKTSWLDGKHTIFGRATQGLDVIRKIEKTRTQRSPEGKPVEDIKILSIDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YF77</accession>
    <name>A0ABR3YF77_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">U-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_006816</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000383">
        <property type="protein sequence ID" value="KAL1886958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46803">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE CHIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46803:SF2">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE CHIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0697">Rotamase</keyword>
    <keyword evidence="6" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="8"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="U-box" evidence="8">
        <location>
            <begin position="199"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="146"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1886958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="275" mass="31785" checksum="7E79F1D8CFF95E19" modified="2025-10-08" version="1">MNRDQDLALELKNKGNIHFVNGDFTAAEGLYSKAIVADPYNPFLYNNRGIARLKLQCYDACIEDCLKSLELSPDSLKPTYYISQAQLELGNVKEALETAKKAHELCIKSKEYKSLAAITQHVLRCKKDHWDQLEKRRIREDSQLEKEALALMLESKQKDLEGIENESDRREIESEWETKMNRLQAIFETSRAKSEQKRTVPDWVIDDISFGIMVDPVITKSGKSYERASILEHLKHQQIDPLTRESLLLEDLRPNLDLRAACEEFLDNNGWAVDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFR0</accession>
    <name>A0ABR3YFR0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Blastomyces yeast-phase-specific protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006679</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000349">
        <property type="protein sequence ID" value="KAL1887139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006771">
        <property type="entry name" value="CetA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36195:SF4">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G01990)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36195">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G01990)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04681">
        <property type="entry name" value="Bys1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047325876" description="Blastomyces yeast-phase-specific protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="185" mass="20248" checksum="69B0BAA6C9EFB117" modified="2025-10-08" version="1">MKFLASLLLTVSCLSRARGGLTLTSKTTVVNKCTYPLYLWSVSSTLSPRYRIAPHHGSYCEFIHTDQLSLKTGIALKITPNYSTLFDESSQMIFGYTLDTEMDPTVLYYGLSNVFGTPFEGMKITLESDDPECSRMEWPDGVNPGHGNFMRACSPDYSVMMVICADGNTASCGGEASGETTETAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFY6</accession>
    <name>A0ABR3YFY6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_006812</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000383">
        <property type="protein sequence ID" value="KAL1886955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22191">
        <property type="entry name" value="IBR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00647">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="286"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1886955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="537" mass="61627" checksum="E008D3E298AE4873" modified="2025-10-08" version="1">MASVHLSHLGSWNPDEITKEDLIGYLSLNQESQHAVIQASRTPAGDPASVLEISPCAACQTNCLIKNENTNWATAWDAFDEFPSETTRCCDSLVCMRCVRRSIKQSFHRHSRMYHWTALEAPGVVFKCPLRCHVSRDEQRRPYGSRELKQMLDDGSDGMKSYTDRFERANRLRQTLSSVTPRLGSVELEEIKGFYQELIDLNLAHDPGYRRLTDATLDQHSVLDRVEALEPIKIYRFLRNGRRVRIPIFLRFLKRIETRSCWICMDEIRDMGTGDSWEAWKDMWAALGNDSVAFKVLSFPLRLQKRCGHDIDFCKDCLGQHIQIEIRDKATDALGNITCPGQGCKRTLRLAEIELYAPPGVKARYYDLMDTAHYSGDPDFMWCINGDCQYGQIHPPNATKVQCSRCSQVMCFQHRGPWHQGQTCAQHDARTDTATDEWLQDNTKPCPKCQTPIEKNGGCYHMTCSSCRFEFCWDCLCDWVYANFNLQRHRPSCRFRQAGIYPTEAVGGLDVEAAIRDVAEIRSADPNVFNNDLHPRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFZ4</accession>
    <name>A0ABR3YFZ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006634</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000338">
        <property type="protein sequence ID" value="KAL1887236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="117" mass="12919" checksum="CA164F92E857B8F2" modified="2025-10-08" version="1">MGPCSSSIGSTPSSEILHMIWTLEAVGTGSNTICSTPMAYNLLGKDANNDAETVARQIEKNFDMTTLQAFARSPSSSDFLFTRSHKSPEYKYDKVVLLILAVPFIATILGTWNRWRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG34</accession>
    <name>A0ABR3YG34_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mitochondrial 54S ribosomal protein rml2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RML2_2</name>
        <name evidence="2" type="ORF">Cpir12675_006686</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000352">
        <property type="protein sequence ID" value="KAL1887118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="entry name" value="Ribosomal protein L2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_uL2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="58" mass="6496" checksum="64DCE8E838F0E8E7" modified="2025-10-08" version="1" fragment="single">DHPHGGGRGKSKSNRNPTSPWGTPAKGGYKTRHKKFNKWVVTPRVRNMGKRRNKASDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG76</accession>
    <name>A0ABR3YG76_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Acetolactate synthase</fullName>
            <ecNumber evidence="4 11">2.2.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">ILV2</name>
        <name evidence="16" type="ORF">Cpir12675_006666</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>2 pyruvate + H(+) = (2S)-2-acetolactate + CO2</text>
            <dbReference type="Rhea" id="RHEA:25249"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="2.2.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="11">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the TPP enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.6" evidence="4 11"/>
    <dbReference type="EMBL" id="JAWDJO010000346">
        <property type="protein sequence ID" value="KAL1887163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02015">
        <property type="entry name" value="TPP_AHAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07035">
        <property type="entry name" value="TPP_PYR_POX_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012846">
        <property type="entry name" value="Acetolactate_synth_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039368">
        <property type="entry name" value="AHAS_TPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000399">
        <property type="entry name" value="TPP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme_TPP-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00118">
        <property type="entry name" value="acolac_lg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968:SF13">
        <property type="entry name" value="ACETOLACTATE SYNTHASE CATALYTIC SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="THIAMINE PYROPHOSPHATE ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00187">
        <property type="entry name" value="TPP_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 11" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="6 11 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiamine pyrophosphate enzyme N-terminal TPP-binding" evidence="15">
        <location>
            <begin position="88"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme central" evidence="13">
        <location>
            <begin position="287"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme TPP-binding" evidence="14">
        <location>
            <begin position="496"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="35"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1887163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="688" mass="74890" checksum="923F539DF2E962C5" modified="2025-10-08" version="1">MYKSRAIQSLARPAVISRASPAPLATASFNAVRGLTSSTRKQATPATASPEPREVPNSNFNATTNDKRHVQSLKSKSEVMDESFIGKTGGEIFHEMMLRHGVKHVFGYPGGAILPVFDAIYNSKHFDFILPRHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMQDAMSDGTPMVVFCGQVPTSAIGSDGFQEADVVGISRSCTKWNVMVRSVAELPRRINEAFEIATSGRPGPVLVDLPKDVTAGVLRRAIPSGPALPSLPSAASRAAMEISRKHIAASMSRVANLINNAKKPVIYAGQGIILSPGGPEILKALADKAYLPVTTTLHGLGGFDELDHKSLHMLGMHGSAYANMAVQNADLIIALGARFDDRVTLNVSKFAPVARLADAEGRGGIVHFEILPKNINKVVQATEAVEGDVAENLKLLLPLIKSKTLADRKEWFSQIDEWKRKWPLCDFERTERPGHIKPQALIEELSNLVADRKDKTYISTGVGQHQMWTAQHFRWRHPRSMITSGGLGTMGFGLPAAIGAKVAQPDALVIDIDGDASFNMTLTELTTAAQFNIGVKVIILNNEEQGMVTQWQNLFYEDRYAHTHQTNPDFMKLADAMGIQHRRLIEPSETTDALKWLIESDGPALLEVKTDKKVPVLPMVPAGCALDEFLTWDGEKDRIRRALMHERTKGQHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGE3</accession>
    <name>A0ABR3YGE3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PUP2</name>
        <name evidence="7" type="ORF">Cpir12675_006729</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000361">
        <property type="protein sequence ID" value="KAL1887040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03753">
        <property type="entry name" value="proteasome_alpha_type_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033812">
        <property type="entry name" value="Proteasome_alpha_type_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="6">
        <location>
            <begin position="8"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1887040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="245" mass="27104" checksum="9D41AAFB36506966" modified="2025-10-08" version="1">MFMSRSEYDRGINTFSPEGRLFQVEYSLEAIKLGSTAIGVATNEGVILGVEKRVTSTLLETSSVEKIVEIDRHIGCAMSGLQADARSMVEHARVECQSHSFNYNEPLRVESCTQAICDLALRFGEGADGEETIMSRPFGVALLIAGYDEDGPQLFHAEPSGTFYRYDAKAIGSGSEGAQAELQNEYHRSLSLEDAETLVLKTLKQVMEEKLDSKNVQLSSVTRDKGFRIYTDEEMKAVVDRLPTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGR1</accession>
    <name>A0ABR3YGR1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peptidase S54 rhomboid domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_006828</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000386">
        <property type="protein sequence ID" value="KAL1886946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050925">
        <property type="entry name" value="Rhomboid_protease_S54"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43731:SF14">
        <property type="entry name" value="PRESENILIN-ASSOCIATED RHOMBOID-LIKE PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43731">
        <property type="entry name" value="RHOMBOID PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="362"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="389"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="413"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="452"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="10">
        <location>
            <begin position="352"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="515"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="135"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="214"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1886946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="554" mass="61214" checksum="5BC367983D0D29F5" modified="2025-10-08" version="1">MGRISSIPKYSTRCVAPSVSLRVNWPKHPNAGNALYQRRNLWTDNVVLTMYETLPRDYKDTTGLTFRKTELSMAEALEIFGPKLSQSSANQLLMILHGRRVAGTLDDPAYRINTAMYTSKQVATGLEYLRKTVPIDETYNAGLRAQDELEQLERQMAKEEKAKLAANATTDTAARETALPVFDPAQVEVKSDPIYGYSKFDELRAKNKARAEAEKQRLAAEEASRPAPTPGSLQEYVQTGTITATSPQMQKWVTNATVSDLEEAPETSKFNRVMPTIALAILFIAGCVGFSLIYEAPPAENRFFVDLRPATACISTIIALNTLVYIGWRIPPLWGFMNRYFIMVMGMPRPISLLLAPFSQSSFSHLLGNMATLYFFGPRLHDDLGRGNFMALYLSCGAVGYAASLLWHPVNVASLGASCAVFGVMSAYFWLHRFDCFKILNLPPDPMEGVPGLVFLSFIIALHISAAMSSSKHVVKLDLASHWGGILTGMFGVQMMEYYGRTNGYRTKEGRFRRGTPAEAENHVPDGQGTVESGGQPGVKKTESIEILTGEKAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGS2</accession>
    <name>A0ABR3YGS2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RTS1</name>
        <name evidence="3" type="ORF">Cpir12675_006761</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphatase 2A regulatory subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000369">
        <property type="protein sequence ID" value="KAL1887008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002554">
        <property type="entry name" value="PP2A_B56"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10257">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10257:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT GAMMA ISOFORM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01603">
        <property type="entry name" value="B56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028043">
        <property type="entry name" value="PP2A_B56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="616"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="39"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="54"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="79"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="635"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR028043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="656" mass="73968" checksum="406E50EBB108E5D0" modified="2025-10-08" version="1">MKRFSQRVLSRGKDPSKSSKKNKDAKDGAVSPSSSTRDVSQSPNVTPSSSTTNLADTRSKQAAANTASGLNGDHGASGSPAQNGAGQSAYSGVQPANGATTTPRHMAAPPTVVVSPSPMHIPPPGAVDTMPGDLAPPKAGSKSLMFDRLHQTPKDVVPEGLRTPKRQHSSRFEISAHRELEKLPGFHEVPPNRRQDLFMQKIDQCNVIFDFNDATGDMKSKEIKRLALHELLDYVANNRQVITEPMYPKVVEMFAKNLFRPIPPPVNPQGEAFDPEEDEPVLEVAWPHIQVVYEFFLRFIESQDFNTNVAKAYIDHSFVLQLLDLFDSEDPRERDFLKTTLHRIYGKFLNLRSFIRKSINHVFFQFTYETERFNGIAELLEILGSIINGFALPLKEEHKIFLTRVLLPLHKVKSLSMYHPQLAYCIVQFLEKDASLTEEVVVGLLRYWPKVNSTKEVMFLNEVEDIFEVMDPAEFAKVQEPLFHQLAKSVASPHFQVAERALYFWNNEYFCNLVGDNVEIILPIMFAPLYENSKGHWNRTIHGMVYNAMKLFMDINSVLFDECSRQYAEQQTNAPMRQALREQRWASVTELANQRLLEIKGPNNGRLVAPMDVLDESDPTEENQKRLDSLNLQDSGDRREHSSADDGSNGEGSALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGV6</accession>
    <name>A0ABR3YGV6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Alcohol dehydrogenase-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006628</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000337">
        <property type="protein sequence ID" value="KAL1887255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050700">
        <property type="entry name" value="YIM1/Zinc_Alcohol_DH_Fams"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695:SF294">
        <property type="entry name" value="RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="1">
        <location>
            <begin position="4"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="223" mass="23432" checksum="50719323F5901851" modified="2025-10-08" version="1">MVLRMALNPVDYKAAEISVGARLVGLPLTPGMDCIGRVSETNTPNLAVGDLVAVKHAAPSKYGVAAEYTIATKKDAIVKVDETGMRTLGDLACSGVASGTALVSLAGLPQGSKVLINDASGAVCSSRNVDLMKSIGAGDVINDTKGDLVTAVRGNAARTGRQFDRIVDNVSTNPQLYYRVHEYLVPKGKLVFVGAPMEPSFIWKALMIHLLPAFLGGGRRKPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGY9</accession>
    <name>A0ABR3YGY9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptide-methionine (R)-S-oxide reductase</fullName>
            <ecNumber evidence="5">1.8.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MSRB5</name>
        <name evidence="7" type="ORF">Cpir12675_006703</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-methionyl-[protein] + [thioredoxin]-disulfide + H2O = L-methionyl-(R)-S-oxide-[protein] + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:24164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12314"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:45764"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the MsrB Met sulfoxide reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.12" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000356">
        <property type="protein sequence ID" value="KAL1887083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033743">
        <property type="term" value="F:peptide-methionine (R)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.20">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028427">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002579">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00357">
        <property type="entry name" value="peptide-methionine (R)-S-oxide reductase MsrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46081">
        <property type="entry name" value="PEPTIDE METHIONINE SULFOXIDE REDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46081:SF8">
        <property type="entry name" value="PEPTIDE METHIONINE SULFOXIDE REDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01641">
        <property type="entry name" value="SelR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51790">
        <property type="entry name" value="MSRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MsrB" evidence="6">
        <location>
            <begin position="9"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1887083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="137" mass="15367" checksum="888183AD9A9D7782" modified="2025-10-08" version="1">MTFPDKRSDEEWRAVLSPKQFRILREKGTERPGTGEYDSHHPSTGIYTCAGCSAPLYRASHKFKSGCGWPAYFDSIPGAVVRHEDRSLGMTRTEIMCSNCGGHLGHVFKGEGYPTPTNERHCVNSVSLRFTEDEKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH26</accession>
    <name>A0ABR3YH26_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Required for respiratory growth protein 9, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RRG9</name>
        <name evidence="7" type="ORF">Cpir12675_006671</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for respiratory activity and maintenance and expression of the mitochondrial genome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RRG9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000347">
        <property type="protein sequence ID" value="KAL1887157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010487">
        <property type="entry name" value="NGRN/Rrg9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13475">
        <property type="entry name" value="NEUGRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13475:SF3">
        <property type="entry name" value="NEUGRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06413">
        <property type="entry name" value="Neugrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="69"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="266"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="80"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="115"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="285"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1887157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="452" mass="51106" checksum="9482163C77A3DC5D" modified="2025-10-08" version="1">MAAHLRISRLAQTFVRLQIDASPSTATLRARQPLARPFYSSSRWEADQSSVAESLLQNAAEPKEAIKTHETSEAQDLVGTRSSESQIAGVSESSPALEATELPYVPPSNPLLDTDSPSVSSQASPNISESQPLTQCASIQQDTLEPSLEQPRQQANNLLSKSHPIEQEDILFEIGPERFPGSLPRRLRLAKPEVAKLDEITIPINDNTITDRQTTAHVQDTSDFHDEAKVVSDILATPSLKTAPPKKKKLRHRDMPPELLHLKLQEKEKQKNSHQHTKGGSYGLKKYENRDSRKPNMPDKRPMWEIQRNALKEKFPNGWNPLKRLSPDALAGIRALHAQFPNEFSTAQLAAKFEISPEAIRRILRANWQPSAEEEAERQNRWFKRGMVVWERYAELGLKPPKKWREVGVGQQAWEEQKKAMGVQSVDEEGLADDTFSGRKQSYQRHLRNKIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH69</accession>
    <name>A0ABR3YH69_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Structural maintenance of chromosomes protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SMC5</name>
        <name evidence="7" type="ORF">Cpir12675_006538</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SMC family. SMC5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000317">
        <property type="protein sequence ID" value="KAL1887474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45916">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45916:SF1">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecF/RecN/SMC N-terminal" evidence="6">
        <location>
            <begin position="39"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="209"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="646"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="782"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="311"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1887474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1102" mass="125928" checksum="D53B7E675B99B1A4" modified="2025-10-08" version="1">MAREYQGDSSQGISPRRQRSEAAQSTLPWTRDNYQVGAIMRVFVQDFLTYDKAEFVPGPFLNMVIGPNGTGKSSLVNAICLGLGFPAKLLGRATTIGEFVKHNQSSAVIETELRGPGPDNINIRVKITRETNQTSWWLDKKSVPHKRIQEVVKSLKIQVDNLCQFLPQDRVVEFARLNEVDLLTETLRAAAPEEVSTTHQFLQVQHKAKEDIQKRIEILQSSLEASQKRQSGLQAEVDRITEREEIRQLIDMLESAKIFAEYNALTESWKRSKHKRKAAHENLQRLKTQSEPALEVLKNKEDYLRSLASSSRERQEKVQQSERAVQQASTKLEEINDKINAFGDEISQADTEYRITKSEAKNISRKLFELQKSQENDPIGELDVEVVNQEIRQNEHLIRDRVSEMQAHKSKIETLRGPMDSKRSEKAKLENNLSALDTQHGQRMNLLRRLSPDAKAGWEWLESNKDRFKMEVFGPAMLTCSVKNDRYADQVEALLAKSDLTCFTAQCREDHTALSEQLYKKMGLSVTIRTCTTRLESMKSPISQDEVQRLGIDGFAIDLMEGPEPILAMLCVEKRLHTAVVSLRSINDAEFSYLESIPAISNMVIGNQGYRIARRRDYGNVSTTNVRQIKQAELLVNQTGGMVTEKQNIERRIAELDDDMAQLRQTALEHKNSYRELGLLNDDMDAKISQLRAKKEDYQRETSRREAIPGKIAKAQADLARLQKAMREKRHAVQDIKLQARLATIKLGPIALSMAAKVVEHREQIKKRAMHNILVIEAESDVQFLCARVENVKRQLKEEQNKVAELAKACDELREQGKSLAKLVGAIKEKYEDPDVLRPFYVDKTVDEVTGKLEAERAKLELLHVGDPATMRLYEELNVTIADTQRHFENSHTRLQEYQKNIDEKQTMWEPQVESLIRKISDAFAYNFEQIGCAGEVRLYKAENFDQWALHIMVCFRCVTTQPNLELVYLLTIHFIPSIHEGNGQLVQLTGNRQSGGERSVSTIFFLMALQSDAQSPFRVVDEINQGMDPRNERMVHNRMVQIACREHSCQYFLITPKLLTNLSYDDKMTVLCIASGPQMPPDVMKLDFASLIRKQRRLMAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIQ1</accession>
    <name>A0ABR3YIQ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">valine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Valyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">VAS1</name>
        <name evidence="14" type="ORF">Cpir12675_006252</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Val) + L-valine + ATP = L-valyl-tRNA(Val) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:10704"/>
            <dbReference type="Rhea" id="RHEA-COMP:9672"/>
            <dbReference type="Rhea" id="RHEA-COMP:9708"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78537"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.9" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000272">
        <property type="protein sequence ID" value="KAL1888203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004832">
        <property type="term" value="F:valine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07962">
        <property type="entry name" value="Anticodon_Ia_Val"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00817">
        <property type="entry name" value="ValRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="entry name" value="Valyl-tRNA synthetase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="entry name" value="Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02004">
        <property type="entry name" value="Val_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033705">
        <property type="entry name" value="Anticodon_Ia_Val"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002303">
        <property type="entry name" value="Valyl-tRNA_ligase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004349">
        <property type="entry name" value="PRK05729.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00422">
        <property type="entry name" value="valS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946:SF109">
        <property type="entry name" value="VALINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946">
        <property type="entry name" value="VALYL-TRNA SYNTHETASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00986">
        <property type="entry name" value="TRNASYNTHVAL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="12">
        <location>
            <begin position="111"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="13">
        <location>
            <begin position="779"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="62"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1888203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1061" mass="120184" checksum="16AD76CBAF9143B1" modified="2025-10-08" version="1">MASASAQTPTDGKDSAPAQPAVPKVKTEKELEKERKKAAKQAKFEQKNKAKVDNAAAPPQATEKKAKPVKKEEEPLPEYIEDTPEGEKKILKSFDHPHYKAYSAVAIESAWYEWWNKQGYFKPQLKPDGSVLDKGSFVIVHPPPNVTGALHMGHALGDSLQDAMVRWYRMRGYSSLWLPGCDHAGIATQSVVERMLQRRENKTRHDLGRERFVERVWEWKEEYHQKINKALTKLGGSFDWEREAFTMSPQLTKAVNEAFVSFHEEGIIYRANRLVNWSTRLSTAVSNLEVNNKELTGRTLLDVPGYDRKVEFGVIVHFKYQIEGSDETIEVATTRIETMLGDTGIAVHPSDKRYTHLVGKNAIHPFLDRKLPIIADEYVDLEFGTGAVKLTPAHDTNDFNLGQKHKLEFINILTDDGLMNENAGPYQGQKRFDVRYKVQEDLKAKGLWVKVEPNPMKVPVCDRSKDIIEPILKPQWWVKTDKLAAAAVDAVKSGEIEIRPSTARNMFLAWMHPDNIQDWCISRQLWWGHQCPVYQAIVEGETTDSANNERWFAGRTEEEARVKAEKALSGKTFKLVRDEDVLDTWFSSGLWPFSTLGWPDNKSLDMERFFPTSVLETGWDIIFFWIARMIMMGIKLTGKVPFKEVFCHSLVRDNEGRKMSKSLGNTISPLDVIAGIKLQDLNDQLLTGNLHPSEVEKATKWQRIAFPDGIPQCGADALRFFMVMSTAPSGGDINLDIKVLAAMRRFSNKIWQAGKFVLGKLPENFKPKPKAEPGVTLAEKWILSKMTTAAKEMNEAMEAREFQKASNLVYQYWWTHLCDVWIENSKSIIQDGTPEEAESSLQTLYTTLEGALLMIHPFMPFISEELWQRLPRRPEDKTESIMLAAYPEFDEKFYSPDAEAAYELVMTCSRGARSLMSEYQIKEEGKVLFQALDETSLSTVTKEIASIKTLCGKGCKEVEILPPSSSRPAGCVAYPVGSEAVAYLFVKGRVDLDAEISKAQKKLDKVETGISKQKKLLADTKYQQKVSAAIRESDAKKMADLESEARGFQGTIKQFEQLKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKK2</accession>
    <name>A0ABR3YKK2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxymuconolactone decarboxylase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_006038</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000244">
        <property type="protein sequence ID" value="KAL1888796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052999">
        <property type="entry name" value="PTS1_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28180">
        <property type="entry name" value="CONSERVED MITOCHONDRIAL PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28180:SF2">
        <property type="entry name" value="PEROXISOMAL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1888796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="255" mass="27538" checksum="05E854F4F360716B" modified="2025-10-08" version="1">MASALAPIITPTLLSAIRTQPNLPSNTWYFITATALSILNRPDEISSVYKYALLHGPGPFDNSPGDDEKLGITRRIREALVKSAAIGGLPKTINALLELKQSTPPAFLDEPLATSPTQRRNEIFGTPSAEVLQRGQTYFDMVYGKITQRVMGNMDRSGTEDLGLTARLMYGYILSNTNVLTPAETSYVILAALIPQDVNPQLKGHLKGAINGGATVENVRAVREVVIKICEASGMKKLSDAASGGWGWKQNIANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM16</accession>
    <name>A0ABR3YM16_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005812</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000218">
        <property type="protein sequence ID" value="KAL1889390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="353" mass="38414" checksum="E68BBD11A876A94F" modified="2025-10-08" version="1">MAPIPITSPSSFFAGLFPRLGNGPTLLDIIFAIIASLLLAFCLAVIGVLVYDYLSRIKRSVWGAIVLAVNICTSARILTWAYERHQCRKLMQRQATLTAERLRREALTPDPGFYSGQAYMIEPARPQKAALANVRHKTAPRRVIRSNKHLPLKPLPSLDIDKESIHSIDTISQSISSAGANKRPLSVTSISSALAIKSINLDNMDQPIQGPYCGDFIFPFSPSDSFCSFHANDSEATYVPEDTSDWANGFTGTYASHGTDMGDNCGFRNDSMKSINGTVKAVEDPTQAIQGSDGGSSNGRASGTTECGNMIVSEYFDDSVESCDSSFADYTPKYYILETGEPIDYFIGQAVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMT2</accession>
    <name>A0ABR3YMT2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin-conjugating enzyme E2 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">E2 ubiquitin-conjugating enzyme 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Ubiquitin carrier protein UBC2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Ubiquitin-protein ligase UBC2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ubc1</name>
        <name evidence="10" type="ORF">Cpir12675_005903</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000229">
        <property type="protein sequence ID" value="KAL1889121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23800">
        <property type="entry name" value="UBCc_UBE2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015368">
        <property type="entry name" value="UBA_C_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09288">
        <property type="entry name" value="UBA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="9">
        <location>
            <begin position="4"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="7">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00039884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00041569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1889121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="231" mass="25619" checksum="01D5DAB49F1F4B85" modified="2025-10-08" version="1">MSSNRERRVAKELRDIAADRDNSGVFAEAVNNSNLMHLRGSLPGPPDTPYAGGTYWVDIVIPDTYPFKPPTIKFTTQMWHPNISSVTGAICLDILSTSWSPVQNIKSALMSLRLLLENPNPKDPQDAEVSKMMIQEPARFARVANEWAAKYAGAPRQENLQNFDALQDAKAEIDYGGWHKDLVERFTAMGFAAEDVVGAFRLLGIEKQGGSFYQLEEAYVGDIIAQLLGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN57</accession>
    <name>A0ABR3YN57_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Protein BZZ1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">bzz1</name>
        <name evidence="11" type="ORF">Cpir12675_005838</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000221">
        <property type="protein sequence ID" value="KAL1889347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20824">
        <property type="entry name" value="C1_SpBZZ1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11912">
        <property type="entry name" value="SH3_Bzz1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035459">
        <property type="entry name" value="Bzz1_SH3_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020454">
        <property type="entry name" value="DAG/PE-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031160">
        <property type="entry name" value="F_BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001060">
        <property type="entry name" value="FCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15735">
        <property type="entry name" value="FCH AND DOUBLE SH3 DOMAINS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15735:SF21">
        <property type="entry name" value="PROTEIN NERVOUS WRECK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00130">
        <property type="entry name" value="C1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00611">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00008">
        <property type="entry name" value="DAGPEDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00109">
        <property type="entry name" value="C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00055">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51741">
        <property type="entry name" value="F_BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00479">
        <property type="entry name" value="ZF_DAG_PE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="F-BAR" evidence="10">
        <location>
            <begin position="9"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="9">
        <location>
            <begin position="406"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="8">
        <location>
            <begin position="583"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="8">
        <location>
            <begin position="682"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="456"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="97"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="322"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="483"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="520"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="533"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1889347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="740" mass="81725" checksum="859FFB5ED08FC90D" modified="2025-10-08" version="1">MAEVVGTAPTLGAELKDGFKPASAWAGNGISWLEDIQQFYRERSAIEKEYSQKLSSLAKRYFDKKNKKSASISVGDTAAMAPGSLESASMTTWTTQLNALEKRAEEHDRYANNLTLRIADPMKVIGIRLEELRKRHIEFADRLERERDASFSDLKKMKGKYDSSCQELEAKRKKTESSFEKAKAQSAYQQQIHEMNNVKNAYLININVANKLKEVYYHQYIPEVMDSLQDLSEFRTAKVNELWTAAMQLESAMLKSSQGIVDHVAEEVTRNKPYLDSMMYIRHNMSAWQEPPDKVFEPSPVWHDDATMVIDEVAKIYLRNMLNKSKGQLSDLRREVDKKRREVDGIRKVKERVREGQENQDEIDVVRQLFAMQEDLHDLDRKRLTVEAETSTITAAVGDVTLGAMNHNFKAQTFKIPSSCDLCGDKIWGISAKGMECRDCGYTCHTKCEMKVPAECPGEQNKEERKKLKSQRQAAATSLLRPDSTSQSQTVDLPALSRSNTVNSTTSGYSASVKKPISVSGLSSSSTPRTPADEPSVPSSEPDPPRASTSSAASGGAPRKNRVMAPPPAAYVSAGAAPTATKPLLQKGKMLYAFDASGDGELTVPEGREVVVLAPDDGSGWAKVRLGYKEGIVPSSYLEMSPAPTATPATIMPIATTPETAQPDHGAAKKKGPVVAPRRGAKKLRYVEALYAYTAQSDSEHSMTEGERFVLSKEDPGDGWVEVEKGGAVKSVPASYVQMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN88</accession>
    <name>A0ABR3YN88_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Glutathione reductase</fullName>
            <ecNumber evidence="3 12">1.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">GLR1</name>
        <name evidence="15" type="ORF">Cpir12675_005656</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 12">Catalyzes the reduction of glutathione disulfide (GSSG) to reduced glutathione (GSH). Constitutes the major mechanism to maintain a high GSH:GSSG ratio in the cytosol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2 glutathione + NADP(+) = glutathione disulfide + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11740"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58297"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.7" evidence="3 12"/>
    <dbReference type="EMBL" id="JAWDJO010000205">
        <property type="protein sequence ID" value="KAL1889771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006322">
        <property type="entry name" value="Glutathione_Rdtase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046952">
        <property type="entry name" value="GSHR/TRXR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01421">
        <property type="entry name" value="gluta_reduc_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004776">
        <property type="entry name" value="PRK06116.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737">
        <property type="entry name" value="GLUTATHIONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737:SF2">
        <property type="entry name" value="GLUTATHIONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="FAD/NAD-linked reductases, dimerisation (C-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="12" id="KW-0521">NADP</keyword>
    <keyword evidence="7 11 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 11" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="14">
        <location>
            <begin position="44"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridine nucleotide-disulphide oxidoreductase dimerisation" evidence="13">
        <location>
            <begin position="391"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00056905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1889771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="504" mass="54681" checksum="E9D261669A452A8D" modified="2025-10-08" version="1">MRIPIRTTLSLPAFRDSGFGRLSSISRHISYSAHNMAPISKETDFLVIGGGSGGLGAARMAASRYGTKAMIIEGGRLGGTCVNVGCVPKKVTFNAAFIADTIKEAKSYGFSYNQTAPFDWNTFKNKRDAYILRLNGIYERNLAKDTVEYVAGWGKFVSNNEVEVTQNDGTKSVVRAKKILIAVGGNPSPPPKIPGSELGINSNGFFDIATQPKKVGIVGSGYIGVEFAGVFNALGTETHMFIRHDTFLRHFDPMIQENMTKEYERIGINMHKKTNLTKVEKAADGTLTLFYKNEDGVEASDSGYNHLIWAIGREPATKNLGLDSAGVASNGKGYIIADDYQNTNVDNIYALGDVCGKAELTPVAIAAGRRLAHRLFGPEEFKSLKLDYTNIPSVVFSHPEVGSVGLTEPEAIEKYGKDNIKVYKTNFTAMYYAMMDPDQKGPTSYKLIVTGKEEKVVGLHIMGLGSGEMLQGFGVAVKMGATKADFDSCVAIHPTSAEEIVTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNH8</accession>
    <name>A0ABR3YNH8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein sum2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_005658</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000205">
        <property type="protein sequence ID" value="KAL1889773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01736">
        <property type="entry name" value="LSm14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025762">
        <property type="entry name" value="DFDF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019050">
        <property type="entry name" value="FDF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025761">
        <property type="entry name" value="FFD_box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025609">
        <property type="entry name" value="Lsm14-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025768">
        <property type="entry name" value="TFG_box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586">
        <property type="entry name" value="SCD6 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586:SF0">
        <property type="entry name" value="TRAILER HITCH, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09532">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12701">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01199">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01271">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51512">
        <property type="entry name" value="DFDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51513">
        <property type="entry name" value="FFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51536">
        <property type="entry name" value="TFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sm" evidence="7">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="DFDF" evidence="4">
        <location>
            <begin position="360"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="FFD box profile" evidence="5">
        <location>
            <begin position="412"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="TFG box profile" evidence="6">
        <location>
            <begin position="440"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="73"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="145"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="321"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="FFD box" evidence="1">
        <location>
            <begin position="412"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="TFG box" evidence="2">
        <location>
            <begin position="440"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="78"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="109"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="161"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="213"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="269"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="415"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="440"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="468"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="500" mass="52169" checksum="39E9E20D9E05BCB4" modified="2025-10-08" version="1">MSEFLGSRISLISKSNIRYVGTLHEINSEESTVSLENVQSFGTEGREGEGAAVPASDQVYEYIVFRGSDVKDLRIDQPPAPQPQPPAVPNDPAILGARPRPDAQGPTNQRPPPAGPPGHPGPPGYGYNNFYGAPGSWGRGGPVPGAGGYGGMHYPPHPNGWGPGGPGGPGTIPPGPGGPPAPWGNYPYPPNMVGGPGGPVNGPTDTQDPKRQQPASSSDSSGQHAQAQDQKNVGAKTSQQLPRTAEADSKPAGPKSEAIEKSTPAVPLSNGQAPTTKFQPPATKSEAASKSLPPPTDAAISDATEAAKAAVALAMARLNAASEPAANPVDNLSNRVNDMRINAATRAPQAPRGGRNQGGRSNRKADVPTEDFDFASANAKFKKDDIKSTTESAANEEKEAATPNEPTPPAGPVYNKSTSFFDNISSEAKERAANGGHKPGGREWRGEEQRKNMETFGQGSVDGGYRNYRGRGRGGFRGRGRGGQTRGGYQNRQPRPQVEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP93</accession>
    <name>A0ABR3YP93_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000192">
        <property type="protein sequence ID" value="KAL1890181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="406"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="448" mass="47764" checksum="58B6127F1F6980A6" modified="2025-10-08" version="1">MAGFTSPTYSDYHSHSHHSSTPSRKPAWLSRIRTLIPVVGAPNNAVPPTSSPASAPLNDRTSDSPLATPVSPISACLQERDEGFYPYNEPATKSDSASSSALSSPTSIQSMSSRATNEASELPEIGQACTVSRRISSPHTVRVVQVISSPWASHGQGRSGSGRGLGDYLPGDCHSIRSPRVLGGEAEEKREVRDLAGATPERQSPLPSTANDEPEPRDKIHGPFPVPSTTVTPMSPELPLAPRLLGSQHKRSGIVQPKLDSARPPMPILHPLHTSQSITAPKTVVAQPLKTAIALARNPTNAAPLPFSFVAVQPFESPQTVGTRPDDDALSTGKLAVAKISNSAKETPPMAIDGALRTLEVPVINVIESSQPQCSMKEGDLNDHDDSEDDIYSSWADYYFDDRNFSQRKESHSGSTPRCIPRATLSSSSQPAISSLQAGKCDTVSIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQA0</accession>
    <name>A0ABR3YQA0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">D-lactate ferricytochrome c oxidoreductase</fullName>
            <ecNumber evidence="7">1.1.2.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">DLD1</name>
        <name evidence="7" type="ORF">Cpir12675_005529</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.2.4" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000193">
        <property type="protein sequence ID" value="KAL1890114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004458">
        <property type="term" value="F:D-lactate dehydrogenase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="entry name" value="Vanillyl-alcohol Oxidase, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-bd_oxidored_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748">
        <property type="entry name" value="D-LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748:SF116">
        <property type="entry name" value="D-LACTATE DEHYDROGENASE (CYTOCHROME) (AFU_ORTHOLOGUE AFUA_7G02560)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="192"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="16"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="29"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1890114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="644" mass="71098" checksum="5E4BCD435A4A4401" modified="2025-10-08" version="1">MMRPQTRSAQTALRCLRAPAQHGPAAPKSRSTPVSCAPTTATISIQRTQTRAISSQEPTPNRPPSNEERLGRSFTGQMMGSIGQRLERERADRQRWRKDDAAPSKMWYTTFLFLFATGSSYYLGGLRPHPPSEESTLPLGRATMPKLKANVENMQAAWVDFITLLGEGRVSTEKNDLDFHSTSSWSAHQAKADDRPFMVLFPQTTQEVSDIMKICHKRHIPVVGFSGGTSLEGHYTPTHGGVCVDFTHMNKIVALHKDDLDVVVQPGVGWESLNDQLRKENLFFPPDPGPGAMIGGMIGTGCSGTNAYRYGTMREWVLSVTAVLADGTIVKTRQRARKSSAGYDLTKVFIGSEGTLGLVTEATLKLAVMPEHTSVAVASFPTIRDAANCVGRVVSHGIPVAAVEILDDNQMQCINQAGMTSRKWAETPTLFFKFSGTERAVKEQIETTKKLSKQAQGKSFEFAKSVEEQHELWSARKEALWSTMAVKKEGDRVWTGDVAVPMTRLPDLIEETKISLKRSGLFGSIVGHVGDGNFHCRCMGHRDLEQSGELTLSFLVILLYNDAQRKVAEGVVHDMVKRAVEMEGTVTGEHGVGLVKRDYLPHELGQSTVDLMRKMKAAFDPLCLLNCDKVIRMNKPKPGDLTQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQI3</accession>
    <name>A0ABR3YQI3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CWH43-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_005314</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000178">
        <property type="protein sequence ID" value="KAL1890590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019402">
        <property type="entry name" value="CWH43_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050911">
        <property type="entry name" value="DRAM/TMEM150_Autophagy_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21324:SF2">
        <property type="entry name" value="EG:22E5.9 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21324">
        <property type="entry name" value="FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10277">
        <property type="entry name" value="Frag1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="CWH43-like N-terminal" evidence="7">
        <location>
            <begin position="54"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="307"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="336" mass="37841" checksum="369D820BB1C660DD" modified="2025-10-08" version="1">MSQLQTATARALTNELIPLLTLNFTDRPKSSRQLEANQTRPKFIIYSSQFTNQMLPVISGVTWLGMLLAMLIYWAGTQDAVHLVDMNEHQSIAYISDVGALTLKPLFIAGCAVTSVFFAVSFIATRWLRHRGRLLPNVTMFQKILMCLNIFSAIVGTAGLIFLSIFDAYRHSGVHNACLVLFLLGFIISAIFACWEFHSLRHCIYALPPPPLVLVFLANNQLLDYVDEPHLKASFYTKLVFIIFEGSLAILFGILFKTHKRNAAAVVEWILAFIFSFYVFSYVMDLWPAVHTKKPEMRYQKPQRLVVGSSGESPHTLEQAIVPPPPPPPEAHMGHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRI8</accession>
    <name>A0ABR3YRI8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">IMP-specific 5'-nucleotidase 1</fullName>
            <ecNumber evidence="12">3.1.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ISN1</name>
        <name evidence="13" type="ORF">Cpir12675_005166</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>IMP + H2O = inosine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:27718"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="3.1.3.99"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3 12">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the ISN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="12"/>
    <dbReference type="EMBL" id="JAWDJO010000166">
        <property type="protein sequence ID" value="KAL1890978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009453">
        <property type="entry name" value="ISN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28213">
        <property type="entry name" value="IMP-SPECIFIC 5'-NUCLEOTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28213:SF1">
        <property type="entry name" value="IMP-SPECIFIC 5'-NUCLEOTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06437">
        <property type="entry name" value="ISN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028836">
        <property type="entry name" value="ISN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 12 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 12" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR028836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1890978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="426" mass="47227" checksum="569F21C0AD003CA1" modified="2025-10-08" version="1">MTTRYRVEYALKSHRRDQLIEWIKALLAVPFVLHSQPAGIISSEDGAVQRMATEAHRRYAEIMSDVEGMIDQDISFRLSQNPLPSKLNLLVPTAGPFFTRLPLEAAFKYQDSVRYISSRRYVSPSFNDVRLILNSAQVMAVTDGSLELATFDGDVTIYEDGQCLEPDSPIVPRLLDLLRRNVKIGIVTAAGYATAEGYYARLHGLLTAIAASHDLTDAQKNSVVIVGGEANYLFKMSLSSEHLLEPVPRYQWLTAEMSRWSEVDITTLLNTAEEALADCVRSMNLPATIIRKDLAVGIIPREPHIRLPRESLEETVLVVQKTLELSSMGLPPGRKIPFCAFNGGRDVFVDIGDKSWGVTVAQKFFRASAGSMIRPENTLHVGDQFLSAGSNDFKARSVATTAWIASPTETLDLLDELSSLLGKKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRJ5</accession>
    <name>A0ABR3YRJ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinase</fullName>
            <ecNumber evidence="4">2.7.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">KCS1</name>
        <name evidence="6" type="ORF">Cpir12675_005201</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the inositol phosphokinase (IPK) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.-.-" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000168">
        <property type="protein sequence ID" value="KAL1890913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.160">
        <property type="entry name" value="Inositol polyphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005522">
        <property type="entry name" value="IPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038286">
        <property type="entry name" value="IPK_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12400">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12400:SF21">
        <property type="entry name" value="KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03770">
        <property type="entry name" value="IPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="187"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="325"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="368"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="537"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="658"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="966"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1104"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1185"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1249"/>
            <end position="1281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1332"/>
            <end position="1376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="231"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="250"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="383"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="416"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="537"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="658"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="718"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="741"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="760"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="913"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="925"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="977"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1111"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1185"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1340"/>
            <end position="1354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1355"/>
            <end position="1370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1890913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1748" mass="189733" checksum="13C5D326B915CC0A" modified="2025-10-08" version="1">MDKNCEAIVSDDAANVAHKTTSVNTPPHNFPPHPSAFASLALESFAPKLVTTSTPPTTLAQNQFLRHPSLPQAQQRCEHPNEESFAQSSPNVATAEAEVAVTAAVTGPPHPVNTKNTDMCRDNTSPLAPAPIAASTTPPFIPLPHSSSPATATPALASALASVTVPVSVPALPLSTTATTAATIAVTAQHHRDHQKKPDGLSSAHVFSPVGADSTCGHGSGPGVNPGFNPGSGSDANGPVSSGPVSGFNATTSTPAPLSSATPSAFSASSLISPSIVSPLLAPSASAKNPLSTTTVGFSSQQALPSSPQLPAKGSSFLSLSSTLRSLDTHSPPRAQYQTHTQNYDHRSQDDCITPTQTQRLVPLPLLKTPTHPQQQSQKALAPLPSSSSSLYPSTPSTQVPAVSNPTNHHEAGAYTTAPTSSVPSSSANSAVSTHSVASSSNDMDVKSDHPPAMAMQRQSGLSLLSQALASARSLPIPSSQQNSATVACSPYTVHPYPPPTSFAPTSSSSAIDCPALPSLASASQIRSPGPIFLESTSSVSTYPSSNANEDQGDDGFLTPRASPRAKPVDQELPAMMTTSATAVPSKADLFRASTEPPSRFMPARESFEIFEGKNRSLLSDSHRAIDPFTDYNCSSNAFASHAPTEYNSFTADSHTLNTTSSYSQPHNQPQASSVLSRHTDRAEPLDPSVPPRRRMTEQSQPHTKRPEKIWSIGSEDGSGRDGQVEKYITDTLNGGDKNSRSRKASHHMRVFREGLPIPESKKPDKSRQGRDREREREKERERLAPVPASPPAKSGIVEDIDDVDTLSKTPKKSGDLPLLKSPTLESKPNILKRSVTGSAISEPKTPRQDPEQDSDLNIFSPFSIAGSVTTTPVAGDRERRASDDSTGNGSQCEEGEDSGEEKISSAVFVLHHQVESAVPEKESVCSTTLEDQPTPNASEDENFNEWLVKADETDQPISPSIEREISKPEQAWPHGSAHEQKQKREAASQPRTQESIPLEKTIPRSFANQSHDAILESNLPDEASELPAVVPQEPVPCQAIELIPYKHQVGGHTTLWRFSKRAVCKQLNNRENEFYEEVERYHRDLLPFLPRYIGVLNVTFQKQPRRKSTYKRDDDSKRHVSDSKTASAPAPRMISQSISSGPASIPTVTFDDNRHIIPRSFLQPPPSSPLIREIIRSRSCSAAATTTASPYTNASARVSGGTSSSASAPQSPQSTAARPRMEDRPNSWGATLINKRLRNEVFNDAFLKQPIPVQKHRKPHEKSVPRPKPNHKHVNSASEPLLSTPEVVRPMANSEIHSLDAKPISAPKAVNDLIDLSPLCELDNDITNVKDVTGTSAPEPERLISRLNDDPSLPKRKRRYSGSGLRRKPVTVSDPRGNLQYYEEADEVDYKNECGRDAPGSVEGDKPISATSQGPGSVIANATLEIDSKLETERKTSHENLVSDEIVQSSPLHVSHLTFEEAEALVETGKIPRPINPKEAQIHPDSRVDYFLLIEDLTAGMKRPCIMDLKMGTRQYGVEATPNKQQSQKGKCAKTTSRELGVRVCGLQVWDVGTQSYVFQDKYYGRKLKAGQEFQDALMRFLYDGVDYHSVLRHIPTILQKLDRLEKIVRRIKGYRFYASSLLMFYDGDVTAESQDNDTAFEDSMTDATDTEDMPRLRRRNRRDIDFKIADFANSVTSADSTDKPCPPQHPNEPDMGFMKGLASLRVYFTRIQMDVRSRLGLDPHGISGRRMDYSEWDAIDDGECSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRN3</accession>
    <name>A0ABR3YRN3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin carboxyl-terminal hydrolase 19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000178">
        <property type="protein sequence ID" value="KAL1890594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="454"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="480"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="556"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="594"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="642"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="659"/>
            <end position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="682" mass="73114" checksum="885DCFBE978CC643" modified="2025-10-08" version="1">MDPRLVIPRDEFNSLQTEVKSHAERLSRLERRQQDDAALKSVWNSPFPSVLTGTPQQDLAEPISADDYFNGLDEQSDHLLGSLHLDPTDEEPIRRGTASRANSVRFAESAIQGSASAWNASQNRTSSDFGLVRPGSSLMMERSLSHKSDGRHSSTGHSVHSILSTMSGRASSLGLDGDDDDDSSIGMPEPPPSLFIMGSVPSIVRCWLTPKFSHDTLLYADICTGSQKSTLEFALAKELDLHHTLERDINGNYTLTLPVYLAEAIVTQPHSRSNNGHSHQIPTVMVTFEVVDLDANDVTEHPSLKIFIGSDALRAHSADVLLSQNKLVLYSTERDKLSVPFVRPEDERVFKNICTRNLARQKSFIRLDATAAPFISGGELKFLSSQSVTKSIESHQSSDDLEGDVNGASAQAYGHSSPDPMPATRLSSSKSAYFPTPFSMRSDASEGDRAVATKEQQQSSRPSLALSENGSLGNQQKQPSASAQATTATQGAASSGSGEPEKRHELNVGIWGSWRNGTISSDRENGLSGYQPAGKSTRTMKVLKPSRNISSARTVPSITTDSTASTSASTIASTAPTTPRTLSDPKRKEGAGQPSASTPTTAPTLAATPPSMTSVSRWESKRSVSATDAKFPTAFPVRDSVRQGSSSSTSSNALPRSSNPVGSASAFSWMNPNGKAKTPVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRN5</accession>
    <name>A0ABR3YRN5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">5-aminolevulinate synthase</fullName>
            <ecNumber evidence="11">2.3.1.37</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">5-aminolevulinic acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Delta-ALA synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Delta-aminolevulinate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">HEM1</name>
        <name evidence="14" type="ORF">Cpir12675_005316</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>succinyl-CoA + glycine + H(+) = 5-aminolevulinate + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:12921"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="2.3.1.37"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from glycine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.37" evidence="11"/>
    <dbReference type="EMBL" id="JAWDJO010000178">
        <property type="protein sequence ID" value="KAL1890592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003870">
        <property type="term" value="F:5-aminolevulinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06454">
        <property type="entry name" value="KBL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010961">
        <property type="entry name" value="4pyrrol_synth_NH2levulA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01821">
        <property type="entry name" value="5aminolev_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF102">
        <property type="entry name" value="2-AMINO-3-KETOBUTYRATE COENZYME A LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11 14" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7 11" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="13">
        <location>
            <begin position="191"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="27"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="32"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU910713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1890592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="624" mass="67366" checksum="EB793BC4BFE39097" modified="2025-10-08" version="1">MDAVLRQSKAVCPFLKQSSPAALRALSTSTRAQPATSASVASTPAMLISPRRGGPMSKLRVLANRCPVMGQAMAVRSAQYSTSATTSVTATSTAASAKPAGLYTQQKRRIHSGKPQGAREADRAVFSSKETAHHKIASINPLSEGPKFDYDRWYQDQLDLKHKDKSYRYFNNINRLAKEFPRAHQATSEDKVVVWCANDYLGMGSNPHVIQTMHDTLDTYGSGAGGTRNISGHNKHAVELEATIAKLHAQEAALVFSSCYVANDATLATLGSKMPNCVILSDELNHASMIQGIRHSGTTKMIFKHNDLVDLETKLAALPTEQPKIIAFESVYSMCGSIAPIEAICDLAEKYGAITFLDEVHAVGMYGPHGAGVAEHLDWQAHATGRPAGSIMERIDIITGTLGKAYGCVGGYIAGSSKLVDVVRSLAPGFIFTTSLPPAVMAGARASIEYQMNYAGDRRLQQLHTRAVKEELTARDIPVIPNPSHIVPVLVGNARLAKEASDMLLKDHKIYVQSINYPTVPVGQERLRITPTPGHTRVYREALVSALDSIWTRLDIKRTSDWAGQGGFIGVGASEKSETPIWTEKQLGIEEATRKIVASGKASVNQVTEALLAQEEPRSTAATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS44</accession>
    <name>A0ABR3YS44_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_005302</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000177">
        <property type="protein sequence ID" value="KAL1890670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1890670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="143" mass="15192" checksum="FCFD20F3A32A0451" modified="2025-10-08" version="1">MARYLALKAKCFGGDILTSTDIMVATGKVSIGSVRPTVEQGEVLQFTLLAKNMIEGNLDRMKTSSELCSVILIGEASFLYPPSLEGVSNIEIPKHAEVANAIGAAVGEVRASIVTIIDKPKKDKCLVQVNKDAFAKAIEKGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT73</accession>
    <name>A0ABR3YT73_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Vitamin H transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_004964</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000154">
        <property type="protein sequence ID" value="KAL1891453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF33">
        <property type="entry name" value="VITAMIN H TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="305"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="394"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="427"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="471"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="521"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="521"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1891453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="549" mass="60577" checksum="76C55AE7B471AC37" modified="2025-10-08" version="1">MSLSIRGPQADPEPAAKPVPLVSADLAKSLPMLEYSAEETEHMYRRLDWRIIPAFWALFFLCSGIRSNIGVAQTMNRKEGHDLMSELELTSKDTSTALALFYIAYTIFDVPSNLVMTRISPRVWMARIVTATGIIGTCFAAVQDAWSLKLLRFLLGAVIAGMWSGMAFYLTMFYPPSHSGKRIGMYYTAAQASAAVVGLVSAGFQKMDGIGGLAGFQWMFLLWGFVTTAIGVSLLWWLPDRPLVPGQVRLRNGFVRFIPATPEALTGRDAQIHYQELRRVYHTRRWRLHDLGRVLIDWRLWPLMLMYFGVVGVGIGTQLYGSVIIASIQPSASTIVVSLLVAPIWIIDLCSILLIVPLSDRYRQYRPFFFIGGACIQIAGLLTTTFAMESGWARYSGLLMVGFGLGPTVPICMAWTTQIFQKRHGDIGVAAATAVVSGLGNLGSITTTYGLYTGWVDDARPGPYRFRKSNLAMVGILCMSILSSLLMFILLRVFGAPPIQELNADIADYAEAETEIACKSQLSPSDMASSEQEKKSGLSEAVQVRQERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTF7</accession>
    <name>A0ABR3YTF7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquinone biosynthesis O-methyltransferase, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">3-demethylubiquinol 3-O-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.64</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">3-demethylubiquinone 3-O-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Polyprenyldihydroxybenzoate methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.114</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">COQ3</name>
        <name evidence="6" type="ORF">Cpir12675_005102</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">O-methyltransferase required for two non-consecutive steps during ubiquinone biosynthesis. Catalyzes the 2 O-methylation of 3,4-dihydroxy-5-(all-trans-polyprenyl)benzoic acid into 4-hydroxy-3-methoxy-5-(all-trans-polyprenyl)benzoic acid. Also catalyzes the last step of ubiquinone biosynthesis by mediating methylation of 3-demethylubiquinone into ubiquinone. Also able to mediate the methylation of 3-demethylubiquinol into ubiquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 3,4-dihydroxy-5-(all-trans-polyprenyl)benzoate + S-adenosyl-L-methionine = a 4-hydroxy-3-methoxy-5-(all-trans-polyprenyl)benzoate + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:44452"/>
            <dbReference type="Rhea" id="RHEA-COMP:10930"/>
            <dbReference type="Rhea" id="RHEA-COMP:10931"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64694"/>
            <dbReference type="ChEBI" id="CHEBI:84443"/>
            <dbReference type="EC" id="2.1.1.114"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 3-demethylubiquinol + S-adenosyl-L-methionine = a ubiquinol + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:44380"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="Rhea" id="RHEA-COMP:10914"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:84422"/>
            <dbReference type="EC" id="2.1.1.64"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 3-demethylubiquinone + S-adenosyl-L-methionine = a ubiquinone + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:81215"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:19654"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:231825"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Mitochondrion inner membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.64" evidence="5"/>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EC" id="2.1.1.114" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000162">
        <property type="protein sequence ID" value="KAL1891133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00472">
        <property type="entry name" value="UbiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010233">
        <property type="entry name" value="UbiG_MeTrfase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01983">
        <property type="entry name" value="UbiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43464">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43464:SF19">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS O-METHYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 5 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 5" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="302" mass="33799" checksum="CE59B613F195EB1E" modified="2025-10-08" version="1">MLSSRFPSSFLRRASRTVRTNTFQPATHLHRQSACLQSSASSPTSSTGSFSSIDPCEISHFNKLASSWWDPHGPSRILHLMNPLRHDFMRECHASQPEPFTPTPASLRYLDIGCGGGIFAESAARLPTTANVLAIDPTPEVLAIAQAHSKCDPMLKTKLQYRQATIEDLPLPTKPEEQFDVVSIFEVVEHVDNPAPFLDRAGLFVKPGGWLVMSTIARTWISWFTTNLMAEDILKIVPKGTHDWNKYLNHDEMTAYFSSRGIWEPPQIMGVMYVPGIGWKRLPGSENLGNYFIAVRKAQDTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTT5</accession>
    <name>A0ABR3YTT5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glutamate--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Glutamyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Cpir12675_004808</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Glu) + L-glutamate + ATP = L-glutamyl-tRNA(Glu) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000145">
        <property type="protein sequence ID" value="KAL1891803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1160.10">
        <property type="entry name" value="Glutamyl-trna Synthetase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.800.10">
        <property type="entry name" value="Glutamyl-tRNA Synthetase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="entry name" value="Ribosomal Protein L25, Chain P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02076">
        <property type="entry name" value="Glu_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050132">
        <property type="entry name" value="Gln/Glu-tRNA_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004526">
        <property type="entry name" value="Glu-tRNA-synth_arc/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020059">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_codon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020061">
        <property type="entry name" value="Glu_tRNA_lig_a-bdl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_bL25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_bL25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049437">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00463">
        <property type="entry name" value="gltX_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097:SF5">
        <property type="entry name" value="GLUTAMATE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097">
        <property type="entry name" value="GLUTAMINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03950">
        <property type="entry name" value="tRNA-synt_1c_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20974">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="Ribosomal protein L25-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic" evidence="13">
        <location>
            <begin position="121"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding" evidence="14">
        <location>
            <begin position="432"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA synthetases class I (E and Q) anti-codon binding" evidence="15">
        <location>
            <begin position="535"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF03950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF20974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1891803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="639" mass="72648" checksum="147F61BA441C7E9F" modified="2025-10-08" version="1">MTPDELTAVAPKLAGDFKSIDAHLRDLDKHLTVRSYLSGYALSPIDSQIWTTLRSNRAAIAFIRKGPLANLARWFNFVEAIHPELQDSIKASENAAREKKLAQSKAGGNYNIALQETEKGVVTRFLPEPSGYLHIGHAKAALLCDYFAHQQYDGKLKLRLDDTNPSKEKQEFQDAIVEDLALMGIKADSLSYTSDYFDYLYDMCKRMITEGFAYADDTDGKTMQDERFNGIASKRRDRPVEESLRIFEEEMKNGTEEGINNCIRAKLSFDNPNKALRDPVIYRCNVSDPHHRTGTKWKIYPMYDFACPVVDSYEGITHALRSTEYTDRNPQYQWFQKTLELRKVYMWDFSRLNFTRTFLSKRKLAKLVDADKVWGWDDPRMPTVRGIRRRGMTIEALRDFILKQGPSRNISLMDWTTIWAGNKKVIDPIVARHTAISVKDMVKVKLSGAEAPAKAFVEDKPKHAKNPAVGTKKMAFSSQLVIDQIDAASFKDNEEITLMAWGNAIVRNSEKTADTIGSMEFELNLKGDFKATEKKITWLSTAGTTLVPAELWEFDYLITKDKLEEDDVLEDCLNPKTAWSEDVLCDEGVGLLKADDIIQLERRGYFRVDKGLGDWKNGEEGEKGKRVVMFSIPTGKAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTZ3</accession>
    <name>A0ABR3YTZ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">chitinase</fullName>
            <ecNumber evidence="4">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">CHT4_2</name>
        <name evidence="15" type="ORF">Cpir12675_005006</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000156">
        <property type="protein sequence ID" value="KAL1891356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06548">
        <property type="entry name" value="GH18_chitinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF384">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="9 11 15" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 11 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046421267" description="chitinase" evidence="13">
        <location>
            <begin position="20"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="14">
        <location>
            <begin position="269"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1891356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="657" mass="70448" checksum="13956ED327932C27" modified="2025-10-08" version="1">MFRKYTAVAALLATRAAFGADDSVKYVGCYPAVTQTQTITVPNGTPGTVTPPTGTAVAGADLVTVTETKYETRIQTLIQTVFVTHDSQILPTSLSSSANATPGLFTSSAATTSLGSHIDPASLSPSASTAPYEHRVAEDVVSGSGATTTTVSASSTEPDTTTKIKSTSTTTVTIPFPSESSAVVGGYNYNATSTALVGTAPALSTTLAGSSTTLFDTASTLSTLTAYREKATSMSMPVNVTTTYGVDTKVSTATSTAAYGSSTPIINGRSNAIYFTNWGIYGANYQPANLPAEKITRVLYSFADISSNGTVISSDSYADFEKHYAGDSWNDSGKNAYGCIKQLYLQKKKHRHMKLLLSIGGWTYSSKFAPVATKPEGRTEFCSSALTLVKDWGFDGIDIDWEYPKNEVETQAYVDLVKECRKQFDAYSAKHANNYHFQITIASPAGPANITNLDLPAMDKYVDAWHLMAYDYAGAWDKTSGHQANVHMSKSNPTSTKFSTDTAVNLYLNHSISADKLVLGFPLYGRSFTGTDGPGKPYTGLGQGTLEKGIWLYKDLPRTGANEHYDADVLATWSYDNSTKEMVSYDNVRSAKEKTKWMLAKGLGGAVYWEASGDKNGTSSIVSTVAESMGDMDTSENLLSYPESVYENIRNNLEEAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXN1</accession>
    <name>A0ABR3YXN1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_004443</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000125">
        <property type="protein sequence ID" value="KAL1892709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1892709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="172" mass="19134" checksum="2EAA94F5CF6FA2D2" modified="2025-10-08" version="1" fragment="single">MEKVGAMNVDTELDTARLHHTEAKKDLAKAISKASKEFYQDLIANMTFLATVQKAAKWLNRPQKPRSQVMMVGGVSHTSTEDKIRALREIHLTESGLPDLDRPEVQVNTGGMWQPVTSAEVESAIRKPLNTAPGKDDIQNKLLAMSWLALGNLITDLFNGCIHSGIHFKRIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXN3</accession>
    <name>A0ABR3YXN3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Swiss Army Knife RNA repair protein HAD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004385</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000122">
        <property type="protein sequence ID" value="KAL1892802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018812">
        <property type="entry name" value="SAK_HAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10335:SF23">
        <property type="entry name" value="OB FOLD-CONTAINING PROTEIN, NUCLEIC ACID BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10335">
        <property type="entry name" value="RRNA 2-O-METHYLTRANSFERASE FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10307">
        <property type="entry name" value="HAD_SAK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Swiss Army Knife RNA repair protein HAD" evidence="2">
        <location>
            <begin position="54"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="452"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="521"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="533" mass="58385" checksum="C5EBBED3DA3D5997" modified="2025-10-08" version="1">MTTAIAASAYAVVKNQTFSVTALGRWSILNRSLPDPEIIKTIHVYDFDNTLFRTPLPNVQIWAGQTIGSLSSNDVLSNGGWWHDCSILAATGQGADKEEACAWEGWWNEKIVELVRLSMQQSDVLTVLLTGRSESAFAGLVKRMVNSKGLEFDLACLKPRVSPTNEVFSSTMHFKQLFLETLMLTYRGTSELNIYEDRPKHVKGFRDFFAEFNYRMGLPSEVGAEAEASSSGHAKSLKRSPIKAEVIQVTDTTACLDPVVEVAEVQRMVNSHNRAIADGTHTGSRLQIKRTVFFTSYSISADDAKKLNKLANLPAHLVSNDIKFHGTNILVSIRPCSHEILNKIGGMGAKMVWRVVAVGHLNNMVWAAQVEPVPANAAYHTEGAVPMVVLAVRKRIRPSDANKITEWVPLAQTDQFSFETTVGEKMTLRMEAEGGDVGEFYRTKATKRKHIASTGGYDEEGPTYSGHGHTKYSTRGDASYEQNDHHRAAHGSHGDGTSPFRGRGRGGRGGRGGRGGANFHARGRGRGRGRGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXQ3</accession>
    <name>A0ABR3YXQ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CDC14</name>
        <name evidence="10" type="ORF">Cpir12675_004460</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000126">
        <property type="protein sequence ID" value="KAL1892692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14499">
        <property type="entry name" value="CDC14_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17657">
        <property type="entry name" value="CDC14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044506">
        <property type="entry name" value="CDC14_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029260">
        <property type="entry name" value="DSPn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050561">
        <property type="entry name" value="PTP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23339">
        <property type="entry name" value="TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14671">
        <property type="entry name" value="DSPn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="8">
        <location>
            <begin position="239"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="9">
        <location>
            <begin position="310"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="34"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="404"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="492"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="428"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="527"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="548"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="570"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="623"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1892692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="641" mass="71277" checksum="A1FB2F83237B817D" modified="2025-10-08" version="1">MSASASHHVDQAVAIIPDRFFLASYHVKPKENTPFVYPDQESPEISRRSPSRKAAPKAPRVHKSPFYFNMDDELLYNAFYHDFGPLHISHLYRFALSFHKILDDLEGNNCPIVYWSKPDPRSRANAACLLACYMVLIQNWPPHLALGPIAQIEPPLMPFRDAGYSQADYGLTVQDVVYGVWKAKESRCIDLHQFDPDLYEMFERVENGDFNWITPDFLAFASPQSSPAVRFPEGSRLYEALPRSLEEIFVHPDLDEPFQNVLAHFSTNNIGLVVRLNSHLYSPSYFEALGIQHIDMVFSDGTCPPLRIVRRFIRMAHDMITVKKKAIAVHCKAGLGRTGCLIGAYLIYRYGFTANEVIAFMRFMRPGMVVGPQQHWLHLNQGTFREWRIEERIEAKLRREIGMSQSAAVPSTPVRSVPKTSRHQTAQTSPSNRSPSSRTPLSEVDDRSNVVAQDDYLPAPTPGQPRKTARIGDRHHPYQRHGNLQANEEEAALQNAAEAASSVKQARPAAESDEEAHLRMKSHRKSSNQPSPSHATRSSTEQTRTRPASSRIANAAAANGAQTASAYKGIDNDASHDTENINSRPLAKVRSSKRTTGSDSTLRSKEGSGVRKTSGRVGSIGNVATSATAAATARKVSATGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYA0</accession>
    <name>A0ABR3YYA0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004242</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000115">
        <property type="protein sequence ID" value="KAL1893223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125">
        <property type="entry name" value="LP07818P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125:SF10">
        <property type="entry name" value="OS12G0136300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="456"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="739"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="212"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="292"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="456"/>
            <end position="468"/>
        </location>
    </feature>
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        <location>
            <begin position="489"/>
            <end position="519"/>
        </location>
    </feature>
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        <location>
            <begin position="520"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="559"/>
            <end position="572"/>
        </location>
    </feature>
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            <begin position="577"/>
            <end position="588"/>
        </location>
    </feature>
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        <location>
            <begin position="589"/>
            <end position="601"/>
        </location>
    </feature>
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        <location>
            <begin position="602"/>
            <end position="614"/>
        </location>
    </feature>
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        <location>
            <begin position="739"/>
            <end position="761"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="770"/>
            <end position="783"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="795"/>
            <end position="810"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1171" mass="126615" checksum="94F1258463DE637A" modified="2025-10-08" version="1">MSKTPRLALGRHSNKSQNAIETSPSSQQHSAEASSTEATATKGPGVPPKYPRNLQSQHSQQPQQPSQHHSHQQQFHSDPSAVPAPRGSLALGDLGSNGTGAPPSAAFELSESALPTPTGPLASAHSAAGPGLLPPKLQLQGIATPVIASSHSKTPHSAKVEDPGSESLLSPSTLQQQQQQQQQQFQYQQQQQSSHLQEHHHQFQQQRHSLEYQSQAQAQTQAHIQAYHQGGAPQPPGKYSDHQQQQYPAQHELQRQRQLEDQQSLHFSQSDSPDTLHHQQQHHQRHQHHSDQLLQPQQQQQQQQRAQYDHEQHLTAPSSPNLGHQSQPENQQPTAASPPKPHRRGHSKSQSQAQQSPLPTQEQPPPVQEKRASTRKFNLRNLLKSVGSQRHHDNPVSPSHDSRTANTNNSINTAVTSATATPPVNGALSPAPSVVIAGATLPDPPLAAVSATSVSASASGPTSAPASGISKPPSTYNNTAGLARRPSKRISTSASTSPSLRTPGQRLSQLAQDDQLSVISQWSQGQSQSQAQSQSQSPAQPQGYHHSQSLSCHHHHHGQSPSTSFFQQSPSSGVDEFDTKSQCKRDSSAIHQQHLSQPQKRTSLSASPTVSSTSINLYPQPDSASFTEDHNNNFVPYPPPKPPHPGQYHQQQQLHYLYSNPNGSQNLSLLSLHDTLDSVSQLSRDSPVDSLPSLNITTPIPAPAVAPAPSVYRPQQPVFADIQQQLSQPRASLEIDLSNCTPESILSPSPATTAPSQQLRSKNMPPAPSSQPNQSAAAQGNPPVYRSSDRAPTYEGNTETGRTSSPQPSTLEAAEEAYNGLNLKYKNVKRAYFEFKKENDKLSGQVEHLQNALANQRMSQSRTALDDNEYVTRFNRLSGAVTNLSFLIRKDWRQPPAWIMPFISPDGIKTGKQEMTAVGRAIITEWLYNNLFQKCFHPGLDSRLSEALKNIDICLRNPAYTFNSQEEWDALTSKLVNWRMATLEGLRPVLQSPVAEDNRLKFIQSKREELVATLHGFLVQPPPPDVEGSVLTIVELAVGIALNLPMESRDVAVLWPQPYDKVDPKLMDAEKTSLPAIKIDSDAAAAAAIAASAAANAASTAATAASGDAGDAAVASAAASAAAAAAANAAEKDKSKKPPPPDPSAVRFAGFLAVEVRGRQVLVRAPVWTIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYR1</accession>
    <name>A0ABR3YYR1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Something about silencing protein 4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004171</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000112">
        <property type="protein sequence ID" value="KAL1893388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038988">
        <property type="entry name" value="Sas4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029184">
        <property type="entry name" value="Sas4_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38422">
        <property type="entry name" value="SOMETHING ABOUT SILENCING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38422:SF1">
        <property type="entry name" value="SOMETHING ABOUT SILENCING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15460">
        <property type="entry name" value="SAS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Something about silencing protein 4" evidence="2">
        <location>
            <begin position="508"/>
            <end position="603"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
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        <location>
            <begin position="70"/>
            <end position="146"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="188"/>
        </location>
    </feature>
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            <end position="310"/>
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    </feature>
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            <end position="383"/>
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            <begin position="676"/>
            <end position="715"/>
        </location>
    </feature>
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            <begin position="769"/>
            <end position="794"/>
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    </feature>
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            <begin position="30"/>
            <end position="41"/>
        </location>
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        <location>
            <begin position="75"/>
            <end position="89"/>
        </location>
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        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
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        <location>
            <begin position="109"/>
            <end position="130"/>
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            <end position="245"/>
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        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="600"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="794" mass="86476" checksum="333B8C4BB62E2387" modified="2025-10-08" version="1">MATTTSRSRRPDTLHAPDACSRPSSSYRPATNTTSTANTAALKPRSSSSGVNLDIRRAFAVAAAAAHVKAHSRVQQGQQQQQQQQQQQYQKHHHHHHHQTTPITGIANVTTTPRSTAPSSQSSPKSTTKPPVAPTGALGRPHQRKRSVDLDALIAPHKKQRLLSATALPRCQSQKNSPFKTPKSLKKQTQLSFKQSLLQLPLQSQQIPTKFSTQILSPAQDTDSAAESSAKLSSIVSPLTPNTAHAHTYTPAPRPQLLTPPESTDTVDQSKAALYSLDITTPCKKASAKPLPTTTQLPHTSASRSASPSSFSEAAAIVATRASKLAGGDVVARVKDRATSTASSASTGTETTPTSLPSRSGRKEHVVQAKAADALHSGNNGRLNTAVSAKTAGKLLSANKKPRKDTSPTESASVSSESQETGGRKLRSQEVTGFKSELALYFPEYDVVIGNVQKEENALDVSTPILISGRVQNTVPAVKMFTDAAFTNVYDVQRLDLSSLNLGEVEEDSLPDIIYEPCHRKAERQEKSVRNTERCRAQHERDQVVRILDSLQGPDWLKMLGVTSVSDSRRKSFEPARHHFIKACEAVLEKFRQWSAEEKRRKAEKERAPSHHAVEFPALIGDRSSGHSSGESSVPPFVMSSHEDDGDGKSIAVVSVTSSNQDAVIEEQLYEETIAAEKSRRSRKRRGPGNASTDDETSLRKRQASPFLPTPPPAQAKEMTSFFAKRHERDAAVHRHRRGGRNILAFGQPLPDMVVQEFELPQALIDETSKTHNGLKSRRSWGKRDEQACPGNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ00</accession>
    <name>A0ABR3YZ00_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_004185</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000113">
        <property type="protein sequence ID" value="KAL1893252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1893252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="132" mass="14763" checksum="C2E6EF909160C5B5" modified="2025-10-08" version="1">MDDDNDGIFSIAILDDEKAAQQTKDREARTALSEDAFQALQQAYEPKRENGELHKALVLPLPKTVSKPEALAVVQAVEELYFYRRFEEAAQLAQSIIAQCGGLYTETVELLRDYEARSRRRASVTGLGKMAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ29</accession>
    <name>A0ABR3YZ29_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="10">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">MNS1</name>
        <name evidence="12" type="ORF">Cpir12675_004037</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) + 4 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 4 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56008"/>
            <dbReference type="Rhea" id="RHEA-COMP:14356"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:139493"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) + 3 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 3 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56028"/>
            <dbReference type="Rhea" id="RHEA-COMP:14358"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:60628"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="10"/>
    <dbReference type="EMBL" id="JAWDJO010000106">
        <property type="protein sequence ID" value="KAL1893649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF55">
        <property type="entry name" value="ENDOPLASMIC RETICULUM MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 10 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1893649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="662" mass="75270" checksum="F90E5D53014A6F34" modified="2025-10-08" version="1">MATARARGIIYTGDILNDVQHKVGDFLDKNNANNQLPMYKDKPYSHTLSRRLRNWKSRRTLAMLGLVLLVMMYFNGAFTRSKKSVWSYDSITASSERINWNKRRSEVVKAFELSWDSYANNAWGYDEYHPISKTAKNMAPKGMGWIIIDAIDTMILMGLSSRLDAAREWLQNSLTWEQDQDVNVFETTIRMLGGLLSAHYLSTQFPELAPVENKDTSLYLTKARDLADRLLGAYDSDSGLPYASVNLHTRQGIKSHADDGASSTAEVGTLQLEMKYLSYLTGNATFWEKSEHIIEVIDGNGAENGLVPIFIYATTGKFRGKNIRLGSRGDSYYEYLIKQFLQTNTKEAVYKDIWDETLAGIKKNLITYSKPTGFTVLAERPSGLQASMNPKMDHLVCFLPGTIALATTGGIPEYRARDQSWWTKEHDENMKLARELMQTCWGMYQVMATGLAAEITYFNVDVKNPPMYDPERKMVPDSVFLDKDPDALWRSDYEVHAADRHNLQRPETIESLFYMWRLTGEPKYRHWGWQMFCAFTNHTTVANQGGFTSLNNADEIPPKPRDNMESFWMAETLKYFYLLFSPSDFMPLTDVVFNTEAHPFPRFDMGHALSTGWKRRERDENGKIIGADKATDDAHEANAGLQLGAGVQGGKLLEDEAEKTMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZT2</accession>
    <name>A0ABR3YZT2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">60S ribosomal protein L24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPL24</name>
        <name evidence="6" type="ORF">Cpir12675_004125</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000110">
        <property type="protein sequence ID" value="KAL1893426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00472">
        <property type="entry name" value="Ribosomal_L24e_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.20">
        <property type="entry name" value="Ribosomal protein L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038630">
        <property type="entry name" value="L24e/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056366">
        <property type="entry name" value="Ribosomal_eL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000988">
        <property type="entry name" value="Ribosomal_eL24-rel_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023442">
        <property type="entry name" value="Ribosomal_eL24_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792:SF1">
        <property type="entry name" value="RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01246">
        <property type="entry name" value="Ribosomal_L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01073">
        <property type="entry name" value="RIBOSOMAL_L24E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL24-related N-terminal" evidence="5">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="93"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="93"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="140"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1893426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="154" mass="17342" checksum="93D1F5797B70CD60" modified="2025-10-08" version="1">MRTYDDVFSGQRIYPGKGKLFVRGDSKIFRFQNSKSESLFLQRKNPRRISWTVLYRRHHRKGISEEVAKKRSRRTVKAQRAIVGASLDVIKERRSMRPEARQAARAAAIKESKDKKSAASAAKKAEKAKNSAGRIQSKQGAKGAPAKGAAKPRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1C5</accession>
    <name>A0ABR3Z1C5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7624 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000097">
        <property type="protein sequence ID" value="KAL1894095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056041">
        <property type="entry name" value="DUF7624"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24616">
        <property type="entry name" value="DUF7624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7624" evidence="2">
        <location>
            <begin position="560"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="441"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="698" mass="77858" checksum="57A7DE6D705DB720" modified="2025-10-08" version="1">MALENPIQASSGDPLSNLSLDNTYIPSTSLPSYQNSRNGSSSNKIPAHFDLISPSDIVGPSPVTSNGTASTEIEDNEQANDAGTQSPQSASEPPQLKMLETNISDSMRLSTGEESISVIHAPQSFLAWSGRDTARSHEASETWESDQDHTADAAAISDKSSTHKQNVTERKTPSALVTNIKLTGYNIDVGTPRAQDLSRDFSDSSRGRPRSSSSLEKIEEIEDGDAIMGDGYRRQYSHSGFEVETLTSALQECWTLCNTLSNLSKIHRTRAFGRLETPDAYEKAWKCCWKLCQMLYTNFDDNTKSLHIDKTLELCREFCQSLFDIRLRPDNAGDSVLRVSFELNNHLFSAQDSSTLPEAFRERTLEFYVTLCHRLMKQRAELTMEADSLLRECWSLAEMLFSLRQKSHEKSSSDLVDILESAIQACWQLCDIFREGWSSIRPDRNTPRPQQPNFFAPQLDVTERSLPERNESRASNRSKASKRESLRSECHLPLPPETPVTEFDETPLSPSLSSPVQEPPNILVLGGLNKEGSRNGRWSSSASNMSGFSHTTAKTSSTITTHLQTESFHAMQIKVLILKLAVLAGFDRDSASDGKSGVTSLQSFAMSMDNELFGKTPKSRNLCQNFKRLIIGDLALPNFNQLPPRGKRVSASEMAKSVNVMIRRSAKYEFLQDLFFRVFNFMPEDVEDNGNGTFSIFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1N5</accession>
    <name>A0ABR3Z1N5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Aconitate hydratase, mitochondrial</fullName>
            <shortName evidence="8">Aconitase</shortName>
            <ecNumber evidence="8">4.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ACO2</name>
        <name evidence="11" type="ORF">Cpir12675_003800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="8">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000096">
        <property type="protein sequence ID" value="KAL1894112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1060.10">
        <property type="entry name" value="Aconitase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="entry name" value="Aconitase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="entry name" value="Aconitase, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050926">
        <property type="entry name" value="Aconitase/IPM_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015932">
        <property type="entry name" value="Aconitase_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006248">
        <property type="entry name" value="Aconitase_mito-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01340">
        <property type="entry name" value="aconitase_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005558">
        <property type="entry name" value="PRK07229.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43160">
        <property type="entry name" value="ACONITATE HYDRATASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43160:SF2">
        <property type="entry name" value="HOMOCITRATE DEHYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="Aconitase iron-sulfur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0408">Iron</keyword>
    <keyword evidence="5 8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha" evidence="9">
        <location>
            <begin position="81"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase A/isopropylmalate dehydratase small subunit swivel" evidence="10">
        <location>
            <begin position="594"/>
            <end position="721"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1894112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="795" mass="84731" checksum="09D099CE1A8743FA" modified="2025-10-08" version="1">MTAFGLARTAGRRLLAVPSTRAYSSTAALPATYERLYTKYGQVRKALGTQRLTLAEKILYSHLDNPEENLLAGTNGGKDVRGKANLLLKPDRVNMQDASAQMALLQFMSCNLARPAIPASIHCDHLIVGSKGADADLSAGVALNKEVFDFLESAARKYGMDFWPPGAGIIHQTVLENYAVPGLMMLGTDSHSPNAGGLCTITIGVGGADAVEALVGAPWELKAPKILGVKLVGQLSDWVSPKDVILHLAGKLTVRGGTGYIIEYFGPGVETLSLTGMATMTNMGAEVGATTSIFPYTNASARYLTATRRAQAAANATNLQNFPAGASGDAVFQFKADEGAEYDQLIEINLSELEPHINGPFTPDLATPLSKFKATVEEQGWPQGLSAGLIGSCTNSSYEDMTKAESLLKQAKAAGLKPVADFYITPGSEQIRATLERDGTLDTFNEAGGILLSNACGPCIGQWKRQDGVEKGTPNAILTSYNRNFRGRNDGNPDTLNFLAAPEIVTAMTFSGKTTFNPMTDSITTPDGKQFKFSAPRGLEGPATPFVEGRESFKALSQEADPSVPIAVSPTSDRLALLEPFPAFPEGEVKGLRVLVKITGKCTTDTISAAGPWLKYKGHLANISTNTLNTAVNAETGEVNVAYDLDGSQTTIPELGARWKERGQEWLVVAEHNYGEGSAREHAALQPRYLGARIVLVKSFARIHETNLKKQGVVPLTFANEADYDLINAGDEAETIGLYDMLKNQGRGDVSIKVTKKSGETVIIPTKHAVSKDQAGFILAGSALNLLSKRVATSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1N6</accession>
    <name>A0ABR3Z1N6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003682</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000091">
        <property type="protein sequence ID" value="KAL1894453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="430" mass="46413" checksum="4BC329B115A1C8FE" modified="2025-10-08" version="1">MITLSEQCSTLARQHYHRVSSLGHLPNHLPIVDDLIRDVKDAQHLNEMLDSAKYVNKASAFKAWERIINSTWSLQVRKHPEILSSGLPYMKIYNMYKHMDTLHKDAAARKLSKNYHNIVKEKVPIVAMGSVRTKNRITNVSSGGGGSLFRSAAVGRTGQSSIFKPTNCRATSGLKSLQQIRRDIRHEKRNTNMGAHSMESKKRAVISQVASPCPGKTYPFSQQRASSLRNGSLESRPGAACTYDHFAARILPSTGLLSDMNGSNGKRKLDEACTRVDGGQPVKKPLLSSLVTAQPPMAGSSGTAHKPKGSSLWSNQRPQSTGLPSQSPPPALPGLPSAARVFPFRSESSALAPDSMPTVVSPKLEASVKTEQSKTKGVSRPKMGLSGMMLAKSKVKSGSSSVRYEARAKPSSVACADSAGRAGVTDTKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1W6</accession>
    <name>A0ABR3Z1W6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Upstream activation factor subunit spp27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003753</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000094">
        <property type="protein sequence ID" value="KAL1894272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10567">
        <property type="entry name" value="SWIB-MDM2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.245.10">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014876">
        <property type="entry name" value="DEK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019835">
        <property type="entry name" value="SWIB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036885">
        <property type="entry name" value="SWIB_MDM2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003121">
        <property type="entry name" value="SWIB_MDM2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13844">
        <property type="entry name" value="SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08766">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02201">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00151">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109715">
        <property type="entry name" value="DEK C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47592">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51998">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51925">
        <property type="entry name" value="SWIB_MDM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEK-C" evidence="3">
        <location>
            <begin position="7"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="DM2" evidence="2">
        <location>
            <begin position="172"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="253" mass="28265" checksum="BBF0462E8815E073" modified="2025-10-08" version="1">MSDPLTAEEISKYTAIVDNILHISDLETVTRKKIRSGLEQTLGGKDLSSQKNAIRDLIETRFDALTQSQPTTPTDSNDTDGQIYSNADEDDVKPPKPHKHSLSVEDADAKLAAELQAQENRLSGARSTRGSTNGVKSGKVTKKKSTPRKKTPKRVSGEEESDPDAPPKKGTGFQKPFNLSHQLAMLVGQPQMSRPQVVKKIWEHIKSNELQDPNDKRQIRCDDLMQAVFKQPNINMFQMNKHLGSHLYPIEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2Z5</accession>
    <name>A0ABR3Z2Z5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SNAP receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PEP12</name>
        <name evidence="4" type="ORF">Cpir12675_003413</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000080">
        <property type="protein sequence ID" value="KAL1894998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15840">
        <property type="entry name" value="SNARE_Qa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006012">
        <property type="entry name" value="Syntaxin/epimorphin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006011">
        <property type="entry name" value="Syntaxin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF38">
        <property type="entry name" value="LD27581P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14523">
        <property type="entry name" value="Syntaxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00914">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0675">Receptor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="3">
        <location>
            <begin position="172"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="266" mass="30331" checksum="1B3B6C095EEBB8BA" modified="2025-10-08" version="1">MSFDQLSHLESQPRASEIYSDDPAFKKLLTDLRNSLFAFQRTCSQLRTDVNLLGTRRDTARLRERVHKLLEKSRDQCKELADGVKKLQSFEDLSKQQKYEQNKVATQFQDALRDFQGLQRLALEKEKASVTAARAAVEGEGGESSGFTEQQQLLQQQELVNLAPQDEVDFQEQLILEREEEIQNIERGVSDINMLFRQVNQIVIEQGESLNTIADNVEQVRDDTRGAMTETAQAARYQKAARNKSCILLLILSVILTIILLAIFLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3Z6</accession>
    <name>A0ABR3Z3Z6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Protein farnesyltransferase subunit beta</fullName>
            <shortName evidence="9">FTase-beta</shortName>
            <ecNumber evidence="2 9">2.5.1.58</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">RAM1</name>
        <name evidence="12" type="ORF">Cpir12675_003407</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-cysteinyl-[protein] + (2E,6E)-farnesyl diphosphate = S-(2E,6E)-farnesyl-L-cysteinyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11535"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:86019"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the protein prenyltransferase subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.58" evidence="2 9"/>
    <dbReference type="EMBL" id="JAWDJO010000080">
        <property type="protein sequence ID" value="KAL1894992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004660">
        <property type="term" value="F:protein farnesyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02893">
        <property type="entry name" value="FTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026872">
        <property type="entry name" value="FTB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045089">
        <property type="entry name" value="PGGT1B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001330">
        <property type="entry name" value="Prenyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774:SF6">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00432">
        <property type="entry name" value="Prenyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 9 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Prenyltransferase alpha-alpha toroid" evidence="11">
        <location>
            <begin position="98"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="363"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="367"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1894992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="536" mass="57667" checksum="BE82DBD05FCED39D" modified="2025-10-08" version="1">MAAASATAPATAATSAAAAATTSAPHISSEDSLWEDIDNASVSDLMIPKLFLGLPPVQDMLATRTSEQQEETLQALMPYLAADLSNKFNYNKHGIASLERPRLAIFLKRILSGLPSPYYAADASRPWFLYWCLGALALLGEDVSEYRDGMVKTAHYLQNRTGGFGGGLGHSSHLATTYAMVLSLVIVGGQEAYEAIDRKAMWEWLSLLKQEDGGFQMAQGGEVDVRGAYCATVLISLLGLPLDLAPVSPLKSKVGASFNLHTKLGDYVRRCQTYEGGISGKPDAEAHGAYAFCALGCLSILDVPYRSIPKHLDVPRLIAWLSARQNAPEGGLSGRTNKLVDGCYSHWAGGCWPLLEAVLNGPMHKNSSSSSATPTASASASASSGRPQVPAAASSATASTTDASPASVASRYNSAEEPFVESIMSREGLIRYILCCCQDEGLRAGGSGMRDKPGKPSDAYHTLYVLSGLSSAQHSWNLYYDPVTTDYTKWEASPYKFTREQIFDEDSRVNTSHPVYVLPPTKVDDVIRYFSKKQGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4U3</accession>
    <name>A0ABR3Z4U3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome b-c1 complex subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">QCR7</name>
        <name evidence="10" type="ORF">Cpir12675_003468</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the UQCRB/QCR7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000083">
        <property type="protein sequence ID" value="KAL1894823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1090.10">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003197">
        <property type="entry name" value="QCR7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036544">
        <property type="entry name" value="QCR7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12022:SF0">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12022">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 14 KD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02271">
        <property type="entry name" value="UCR_14kD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000022">
        <property type="entry name" value="Bc1_14K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81524">
        <property type="entry name" value="14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1894823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="123" mass="14444" checksum="A030972F7FD009B7" modified="2025-10-08" version="1">MSVSAAKFVIERPWLLRALTPVAQWYGNAQGYRQLGLKADDLWEEENEVAQIALKRLSEKEHYDRIFRIRRAVQCSYQNKLLPKSDWTKPEDDMPYLEPIINQVRAEIAERKALDSMEVIKSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4X0</accession>
    <name>A0ABR3Z4X0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003273</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000075">
        <property type="protein sequence ID" value="KAL1895316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="387" mass="42050" checksum="4120D77C58B6921B" modified="2025-10-08" version="1">MQFHSRTRSTDNTTTFAAITGKTSRAAKRASRGISLDRRPSPPMMHRGNAAAASGIDPLDSIRHKAPFIGVVSTYGDYPRDTFLNALFNPDLRPPIPGQTRPYTSVTLQDRPWRYWVDQVVHPLAQPDHFIGQLAQLDVLVVLYSTQSASSFISVIKICERYLDAVPPYGSNSENTTSPAALSAVTPGYRNIGRGLPLPVIVATGSAPIKSLVVRDGHVPSSKGIALAAKYNGRFVELDSFTDACEVQRPIEAAVAAWAKGHTQVDLLLVPSTGSNRSENDGSPSESVPPSNSRRNTDTRDKRKNSSHTERRSKDSRSSLPTSVEHRGEASGTAAAPKTDVTPKSPTSIFRAPTESGDSADFQQRKKAGRMSRMFQALKRRVNSSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z539</accession>
    <name>A0ABR3Z539_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003289</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000075">
        <property type="protein sequence ID" value="KAL1895332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="412"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="714"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="787"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="89"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="197"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="463"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="791"/>
            <end position="806"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="856" mass="93588" checksum="A0C54E0F4247950E" modified="2025-10-08" version="1">MASVKTSVSSCAAPLALSEAEKHQFQQYKKIIALRDIVLSGGHPRIKIPARLVGKVPPPHAVTSPVLLLSRPGPSARDSAASATLNTDSTAAYSATSPSAPDFKTSPGTAKPVVASEPSNTVKSNVEINPVLLQKSDDLIRAEFRVRRQRIENSLQEELETKRLANKASIYPESELDIAKIYETAQKLVAAADASTTANVVSTSSNSVPDPASAPIPDVDSLSNASYYSSRHDTPISQDDQPMSIDDAASVGNPSRTHGHETAPSNAPVSVPNPTAVSCSSLATAPPVVPPATAAISATIATASVATLDSTTAQPPTATSNFSPLHPMTCSVVDYSHSSRERQVEIDSALDSDSVPAVPSGPMQYQRTRRVYESEQPPPSIFRSHNLVPAAPQPYHVSSLATRDGVQAVEASMVSPNERVASHKDVSSGSTGTSPKDRGKQRKNKSKKRKQDRTGEPVTVIKTEPKSPEMKAPEYAPRKRQKGKRIYVSADEDCVQYSPGDSLTADPRDHTYHRAPGHYVSYGDHEPYRRRVAEPVHERVFIEPGPSSSRPPHYVRPAYNLYSTEERYPTERQASRYYHESHEPGPASVAIRHEFEHRATSPAIADSEPAAMGSLRASSGVVVVDDYGRSYYEPSRPSYPRQPHYGEELIYKRAVSRRPAPTEYYDDGPVYCRTSPVAFGTYPRRATSPTPFGAYAPRHVVTQSEVLDSGMRPREYSARPVGPPVDDYVSVRPTPTDRRDYDEPAMYSRPISVRPPLDGSFAPTMPPHPHPLGNSEFHRTASVRLPDSGDLPPPMPPQRHFMPPPSTARACSVVPAERMQRNYSVHPEVEHRYYTNEIEYVGRTPNGAYAERAYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z540</accession>
    <name>A0ABR3Z540_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Spindle pole body component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_003284</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
            <location evidence="5">Cytoskeleton</location>
            <location evidence="5">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TUBGCP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000075">
        <property type="protein sequence ID" value="KAL1895327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF70">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="8">
        <location>
            <begin position="195"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="7">
        <location>
            <begin position="650"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="580"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="581"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1895327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1035" mass="115041" checksum="767D1C139FD1D779" modified="2025-10-08" version="1">MTQAFNFKPSATSSPADVFAIPDLWRSSKWLFSDSEDNINRLNTLYFSENISEPSIKRPVIDTSVPCSPFFKLPQIDPGVIIKPPPLLHLNSADASGLADKAPAIGGSSTPSTAEAVDSAFVADDDVWLAASQPISKRPEYQSWAAFTSLEDDPCDPEALLITEAPSEVYDAVLAEAASDQAPEKIADTSIYMSCLLSALLGRESLFFVWNDDKTAIILTIKNLRVSGYSQRVLGRLESLCLNCGILFHRLKSFVQSTYSKTSSRCRVALGSAIDTVLSVVESDIALYKQPQSLLQLLVLVNKVHLIFAQFYELVSRLAAKHPDEVILQTVFQHAQVSEYNPVPLHDAMRILLQRVSQPWIDFIEEWVGLKHEDGMPMSKDDLGASKHFVKVESEIFVDDFSEEVEEIDFRLDRAKMPDFVPKDMADSIFEAGKNIRFIRSEHSEHPLANLATVVKSNPPESVWRYDWGAILDLEKRALEYEASLINAINEARAQQRKAPASYTALNDRPGLLGSLALSSSLGATASDLAFANTTWGLQIYGFDEADISSHLQVSMNELSEPLPEVIQKDALADAIRDCLQSHQQEESQPQTSSSQLPSTAKERILNSNAHLVSPHWSLLPLLSFNPLTSAHGKVVNRESLKLLFSHHDLLGHLRLQKDFYLFGNGRFASRLTHALFDPQLETAERTAGVVAQGGIMGLRLTSRDKWPPASSELRLALMGILAESYASESSVSLGSTSTSAHNANISGNLPGDLSFAVRTMSEADIQKCMNPDALEAIDFLRLSYKAPPALAPIFTPLIMMQYDRIFKQMLRVARLLYVVDSLSREAISLRSQRPQATVALRFCYEAHHFVYTVANHFVDCGITLPWCAFETWLASVQLDLTTQSKSPSASSSPFAPHSHLRTHSPERLRVCHSMILDRMLISLFLRKRQQPVSQLLNDIFGLILQFDKLARVSSVHDNVDQMTTLYAAFRAKIELFISVCRGLTEKSDITVRYESREKADEVRAELGEALDGNTVAMLLMKLDIAGFYLKGQDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5C3</accession>
    <name>A0ABR3Z5C3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">tRNA-splicing endonuclease subunit sen54</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SEN54</name>
        <name evidence="5" type="ORF">Cpir12675_003053</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEN54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000066">
        <property type="protein sequence ID" value="KAL1895831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024337">
        <property type="entry name" value="tRNA_splic_suSen54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024336">
        <property type="entry name" value="tRNA_splic_suSen54_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21027">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21027:SF1">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12928">
        <property type="entry name" value="tRNA_int_end_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA-splicing endonuclease subunit Sen54 N-terminal" evidence="4">
        <location>
            <begin position="81"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="441"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="446"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="471" mass="53311" checksum="CF48904E41AA0018" modified="2025-10-08" version="1">MLDDEDAPNLDRTAADEGHMDEDGAEDLAPDFRLFEAMLKKKKGYSGTSIRKGEKDFEQHGTRAQLNSLEHSRQVMEEIQSYERFHKYDTWNRGWFFPTYWASALGDKVKDSSKFKEFGKDDLFLRNRVVVVEMFTGTLQKSIGRTIPGVTKFHPAFGKSWLLPEEALFLVERGNLDLWYPNEPIESLMPGWPREAAEQRGNNEKPFPQSKPDPSDYSKGTPLSLQAAYAMLIGIEGEEGKVSLRKYQVYAHLKRAGFHVFPAWEEDEEETAQPWSLWSWMTSLLDISSPCQSQNGPLVHPGVYHSYKSVYSRLQQIPRHVPKKIAACSKNSKKPFKLDYFVWKADGAPFTKGKPRAPDFRVCVVDAKDTTIPTLDQIAALLEATPYSPPNESWQGPGRMHQRLKHGHRNVLIAVVDCGIISFSRFSEAAFALEDQTPRFDASRSIRGRKNGGGRGRGRGRGRGRGRGRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6X8</accession>
    <name>A0ABR3Z6X8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002937</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000063">
        <property type="protein sequence ID" value="KAL1896024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="10"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="102"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="150"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="350"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="913"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="157"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="323"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="431"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="464"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="474"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="500"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="525"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="950" mass="100862" checksum="B19184B9A8827823" modified="2025-10-08" version="1">MLELDAAIHDVDALVSDEPWDARASSRSSASGTPKPPPGLGLPAPPGLTPIGMASNPPSLPTQPSTSSPIVPIVSTSLANAPVIKTKFSIPIGSPVDPPAVANATSTPVTSPKAKAKAKASTSRDVLSTPERHTTLTKIAIAIAAREGGKDKDVKDTTLSSGSTESAALQTPRTPLKAPMRAVSTSILHDEDFPALDSHKTDTMRTPVSDTLSRILVTSSPKKSLVDSSTKPKRPIILSLNTSSPILNKANSSVKAMATATATITPVETPTVLSRSVSTSATNPPSPVIRAIPRSIRLTGTTTLSRSDSAPLASPIVLAATPNSSHLQRASTPTSNSEVISDSASIVSTSISLSRTSSPPPPPTANRVGTAPVRTTTKSQQRKQRKDQLKVDTVATESMLAPQQETTHAPVMGRKKKQKKEKPTFLKKGPSAAISASASLAEKDGSDIPPTLKTREKTKISLAPNIQSPDLNKSSPTTTSTISGSSSSQHHTSSNISQALDETTATTTNKKGQEFRPQGQEGKANNDSVDSASASSPIIKSPQKTSVSNNQTLAKSERIQIKDVTAKKEPLLITAEKVAAEAVAQTERSTDIHKGQSHAVDISGSALSKIFSGLRAQRRLPEADRLSFFRPLNSDNTKAEVEKVFSVPGPGMSETRILSNADSSSAGKIQVNMGEDTAISILTSDEKKQLYESKPVRKFCDGSRVLITPNGDFVRNLSQEEEDLYIYYQAKMVSDLQDPLTFIFDAYRRGTQGFTLVNNRAVPNGPPSFFPQTTDGKVHDPVAKIQRDEAISYINQFVLPGLQLDRQSSTGQSARDAAADASLYSLAPFIYNCDVPPTQMYGASGLSSDDAAALLTTYTGAVSSIDYQSLSTSSYHSMPTPTSTSMPSLNNLRNPLGADCGMLSLQSPPPMSVEDLEKALKLARREVEKAEAKLNQVIKNNRRLILGTRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z754</accession>
    <name>A0ABR3Z754_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AMP deaminase</fullName>
            <ecNumber evidence="4">3.5.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">AMD1_1</name>
        <name evidence="10" type="ORF">Cpir12675_002770</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via salvage pathway; IMP from AMP: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.6" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000057">
        <property type="protein sequence ID" value="KAL1896481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003876">
        <property type="term" value="F:AMP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01319">
        <property type="entry name" value="AMPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.800.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006650">
        <property type="entry name" value="A/AMP_deam_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006329">
        <property type="entry name" value="AMPD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01429">
        <property type="entry name" value="AMP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11359">
        <property type="entry name" value="AMP DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11359:SF0">
        <property type="entry name" value="AMP DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19326">
        <property type="entry name" value="AMP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001251">
        <property type="entry name" value="AMP_deaminase_met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00485">
        <property type="entry name" value="A_DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="235"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="855"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="243"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR001251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1896481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="877" mass="99639" checksum="E7A216C54A534B8B" modified="2025-10-08" version="1">MPDTISTSYPKLGSQFLLHDGDSEDDGPALRHQDSAGDSEFEDTDPADPTPNKISEDMELNSQDGMLARDRRQRSAFYNPVVERQMSQEDAKLIFQNHKSRSLNSPLISSTSANVPGPQLELPGPSIDSAEGSTNSPVVSVAPSINQNAPLSPVVEDEAAQPAPSAYYHQPVDFGGGDTSLFDTEPHITAELSAIAAKVQKALDMRKAYMDISLQGPNDNPKDTPEWDIYPPAPEPFWDHAHSSTANLSSAEPMSTTTQRRTRRRKQGQDIGEDFVREDLPVPNTSDLEFRLDVNGIFQVYKSIADADENKPIIKVPTMRDFYMNLDEVVSISSDGPSKSFAFRRLQYLEGKFNLYMLTNEYREVADSKKVPHRDFYNVRKVDTHVHHSACMNQKHLLRFIKSKMRKSPDEIVLYRDGRHLTLAEVFQSINLTAYDLSIDTLDMHAHTDSFHRFDKFNLKYNPIGESRLRTIFLKTDNFIKGRYLAEITKEVISDLESSKYQMVEWRISIYGKAMDEWDKLADWVVENKLFSHNVRWLVQVPRLFDVYKASGLMENYESVLDNLFRPLFEVTKDPSSHPNLHIFLQRVIGFDSVDDESKPERRVYKKFPVPREWNSNQNPPYSYWIYHLFANMTSLNNWRKSRGFNTFVMRPHCGEAGDSEHLAAAALCCHSISHGLLLRKVPILQYMFYLDQIGIAMSPLSNNALFLAYERNPFHQYFRRGLNVSLSTDDPLQFAFTKEPLIEEYAVAAQIYKLTPVDMCELAKNSVKQSGYEASIKQQWLGPDFSKPGSEGNIMAKTNVPNQREEFRYQTLIQEKRVLQQYIAFTNKEAKPTVIIPQIPAPIPSVDPTAAEPTIFPGLESRGARTTSVKGTGDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7Q8</accession>
    <name>A0ABR3Z7Q8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cleavage/polyadenylation specificity factor A subunit N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002925</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000062">
        <property type="protein sequence ID" value="KAL1896217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014839">
        <property type="entry name" value="Crt10"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08728">
        <property type="entry name" value="CRT10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1896217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="846" mass="95136" checksum="1B640439C45C55C5" modified="2025-10-08" version="1">MPTMAGKLRVSAAYTQLPDDRFHLRPVRNDINEFQITDDPNNMDQLAREETHDYLASNLPQSQRGKCWCTTGRYFAQMGKAISFADLQSPEVPRVQINRNNLAALSQAYNLYFVAMSHRLYVYRPRTNLTQLIPAKADLLLYSGPSPEAMSIHGHQDSVRCHDANTITTGFLGAMEIVVTSHDDGDVVVYATSHIEKYVRFLLANEGRHPTPADGDIRFPEPLYHFNVGLSAWGIAIHQKSRLIAISSNRHEVTIFAPASNGTRGLPLISPRISSQTKFINSGNEDLFIIVLLRNRIDQHLPCIEFMEDKEGFAIKVLVGALGGYLWVADIWERGTTPGYYHELLLAGSGVSCIWSLAALSEDIFVPCSSHEEAMTSTMEPSRFKCSDSIDRSDRVLDITPLPVDPEESMTYPMQEELRFYRIRTPPNYSLDLSSRDLIQTRASLYELRTSVWGLYYTPAGDSLYEEFEGLDLGFMYEEDEMGQSHSENLEIQDSTREPDTGVGAYPTAAMTAELLRMSTNDYSVPPESIIRDEGDTSALRDNNSNIIVDKNILSTITYNRLEPNETALSQLDSLIHLTTLRNSREYIPGTRVALSTVTQIGLYPTNHQDLVSFLKRKFQPLHTVKEQQLTELYKNGSPVRLLLGLSKEALVMSPNPGDIAEDMVMYGELSRPGAGPDIGNPRLHLMATIPELSLIIVGNITGCVSMLTPTRVPNKFSQGRKDNIRYTFAVETQLPQWDDETVALIDGVSLVGLSCSPLFEEKEPTDLHTELDLGPRAQSYPGPGWRFDSEGLDVDYLVPWRHRRKEKLFNMGVVTGKWRVMLYYDNHTIITYIVERDTSGNIMVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z804</accession>
    <name>A0ABR3Z804_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002912</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000062">
        <property type="protein sequence ID" value="KAL1896205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031355">
        <property type="entry name" value="YBL010C/LAA2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38698">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38698:SF1">
        <property type="entry name" value="FUNGAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17104">
        <property type="entry name" value="YBL010C_LAA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="510"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="317"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="547"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="645" mass="69785" checksum="B7B40B5DBC4139F0" modified="2025-10-08" version="1">MASSSETHDPDRLEPPARTGLADPGAHDLGESSADESEDYFSDAVSDMNSPSSALYSDAKTKTGAGDTSIQTAEPIAVDTLDARTSSETINAPCPIETKEESEEETILETKPEVEIEADREIKTEAGPEENGSGNKETEAISNATKGNLDGQVNNKSDDQTQNIVPAKLADEVKEHALESQNSEDDKPKDDNAEDEELDETSGISLLDGMPIPTTILEESPGPIPPRSFHVEHTHATDSAPDMVIKPDPDEQQKIISEEATFQEIEERFKREELASKEDADDPITTHSNTLTLGKPHQRPVVFHSVLTDLSINAEAPKSPSLSTPSSPRARRRSSVRNSQSPMGSTLGPPSGDDFDDDFGDFDDFEEGGDDDGFGDFDDVAFQEPVAAPVVQQPVPPQAVSTAPPLPHPVPDFEGLDEDDIPEALDPYMNLLFPPENLNVIDLPPLNKANTSFLTQRSASLWSQLVAPPPLAPPDWIRSRIRRLFLVSLGVPVDLDEILPASKQKKLVLPSLQVPSTKSPRTSTDSRSNKSGGNNDGTSASQANGASKGSSISRNGSSRRRKGDKGPPELDLVSSKQLCMTTEEALAGMTLGELKAHLKKLKALKNTAEQSLEYWHKTTAEKVSERDALEGVIENLVKHARKVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8E4</accession>
    <name>A0ABR3Z8E4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Phytase A</fullName>
            <ecNumber evidence="4">3.1.3.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Histidine acid phosphatase phyA</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Myo-inositol hexakisphosphate phosphohydrolase A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Myo-inositol-hexaphosphate 3-phosphohydrolase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Cpir12675_002583</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,5,6-tetrakisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77115"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57798"/>
            <dbReference type="ChEBI" id="CHEBI:195535"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:77116"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>1D-myo-inositol 1,2,5,6-tetrakisphosphate + H2O = 1D-myo-inositol 1,2,6-trisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77119"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:195535"/>
            <dbReference type="ChEBI" id="CHEBI:195537"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:77120"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>1D-myo-inositol 1,2,6-trisphosphate + H2O = 1D-myo-inositol 1,2-bisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77131"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:195537"/>
            <dbReference type="ChEBI" id="CHEBI:195539"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:77132"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>1D-myo-inositol 1,2-bisphosphate + H2O = 1D-myo-inositol 2-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77135"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:84142"/>
            <dbReference type="ChEBI" id="CHEBI:195539"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:77136"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>1D-myo-inositol hexakisphosphate + H2O = 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16989"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57798"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="EC" id="3.1.3.8"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:16990"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.8" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000052">
        <property type="protein sequence ID" value="KAL1896935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016274">
        <property type="entry name" value="Histidine_acid_Pase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963:SF24">
        <property type="entry name" value="3-PHYTASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963">
        <property type="entry name" value="MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000894">
        <property type="entry name" value="Acid_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00778">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="18" id="KW-0472">Membrane</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00042300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00043670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00043748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00043788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00044106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1896935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="503" mass="55722" checksum="4E20885A5B060FD7" modified="2025-10-08" version="1">MNVITSAYGAVQSALTARQFQYQPIGGNRRRGVFYMLRASGSRRKVQFTMAAMAALLVGAIVVGLSSSACFECLFAVNPSLWGQYSPMFSVPTDISTAVPDQCKLTFGHVLSRHGARDPTMSKTKALNATIQRIHDDVLTYGPGYEFIRNYTYSLGADQLTDFGQRELFLSGAHFFNRYLSLAENSVPYIRASGQDRVIMSAVNWTQGFYDARMNKGIESPEKSRGTMLIIEENSTSNNTLNNNLCTAFENGTYSTIGDKAQAEFLATFIEPVTARLNANLPGANLNNDEAIQMMDMCPYSTVASRNATISEFCDLFTIGEWLSYDYYQSLNKYYGFSHGNEMAATAGVGWVNELIARLTSQPVIDHTSVNHTLDSSPETFPLNRTLYADFSHDNDMAAIFAALRLHDGYTKLPTNKRVSPTKTGGFSASWVVPFAARLYVEKMQCGGQDDEPNEELVRFILNDRVIPLVGCGADALGRCKLSKWVESMEFARTSGKWSQCFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8L2</accession>
    <name>A0ABR3Z8L2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002819</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000059">
        <property type="protein sequence ID" value="KAL1896415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="232" mass="25725" checksum="EF947FD9F25F8FCC" modified="2025-10-08" version="1">MALNLEYVLAAALSCGLIIILSTSLYKYNSYCRQQPRKQPPTLPFYVDLKQPPVERSRSFSPAQSPSPAAFLRMAPPAGLAGQQTTWPGHLDSTTLFSQSLFSMPSFSRDAFESFSLTFNNIDYSSQTSTEKLSTEQAPDDLTPLSSRAPSACYSQRPRAMYWDDSFYFSQHCITGDDEPAVVTALSPAVTRRPSQADSIDDDEPRLNKPESQQIIAPHKLIAALEAMQINM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8T8</accession>
    <name>A0ABR3Z8T8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002569</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000051">
        <property type="protein sequence ID" value="KAL1896988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1896988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="101" mass="10926" checksum="7DCFCE72C3A1FD8B" modified="2025-10-08" version="1">MFNTIIIGGGPAALLAALRLHRSNSISPVLYEIHREPSTLGGASSELGDAIREMIQKTETVKFYPIYKLPAGGLGSRIAASSLGMLLTLCHLMLAKEFQWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA30</accession>
    <name>A0ABR3ZA30_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">6-phosphogluconolactonase</fullName>
            <shortName evidence="2">6PGL</shortName>
            <ecNumber evidence="2">3.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SOL1</name>
        <name evidence="4" type="ORF">Cpir12675_002506</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12556"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="3.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.31" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000049">
        <property type="protein sequence ID" value="KAL1897185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01400">
        <property type="entry name" value="6PGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005900">
        <property type="entry name" value="6-phosphogluconolactonase_DevB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039104">
        <property type="entry name" value="6PGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01198">
        <property type="entry name" value="pgl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11054">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11054:SF0">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine/galactosamine-6-phosphate isomerase" evidence="3">
        <location>
            <begin position="11"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU365095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="259" mass="28157" checksum="14BB90D0D8DCE665" modified="2025-10-08" version="1">MGKTSLFSFADADALAAGLRAYIVQAQNAGFMRHNTFKIAVSGGSLPKNMSKALLAPSKGPKDVLDFSKWEIFFADERVVPLDHADSNYALLKTEFLDKLPAGTGMPTVHPIDTKYLDNLQELADQYEQALVKSFASRDSVKLPIFDLLLLGCGPDGHTCSLFPGHELLRETSAWVAPIEDSPKPPSQRITLTLPVVTHGVRVCFVATGASKQSIMKQIFDEESVLPCALVNDAAGDRCAWFVDDAAVEGVAYTRRSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA78</accession>
    <name>A0ABR3ZA78_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hym1p</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HYM1</name>
        <name evidence="2" type="ORF">Cpir12675_002291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mo25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000043">
        <property type="protein sequence ID" value="KAL1897563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013878">
        <property type="entry name" value="Mo25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10182">
        <property type="entry name" value="CALCIUM-BINDING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10182:SF3">
        <property type="entry name" value="PROTEIN MO25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08569">
        <property type="entry name" value="Mo25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="370" mass="42348" checksum="93786DC795DD25B7" modified="2025-10-08" version="1">MSFLFGRTRARTALDLPKQAREHVSRLSMDWAQGAPVKTEELAKVLGQMKLVLQDDGDTSSDQIYQLVTGIIEEDLLYLLAVNLHKIPFESRKDTQVIFSYVFRFRPTGASPKSDPVALSYVINQRPQVLLELCRGYDHKESATPAGSVLREVLKSESAAAIIMYDDADDKGSSFYGVSNIDRDKPQSGRGVFWRFFDWVDKSSFEVAADAFTTFRELLTKHKDLAPRFLSVNFDLFFGQYNSILVQSNSYVTKRQSIKLLGEILLDRSNYSVMTAYVDSGEHLKICMNLLRDDRKMVQYEGFHVFKVFVANPHKSVAVQKILIMNRDKLLSFLSHLLEDRTDDEQFIDEREFLIKQIKNLPPSPVPPQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAB4</accession>
    <name>A0ABR3ZAB4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Altered inheritance of mitochondria protein 41</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AIM41</name>
        <name evidence="4" type="ORF">Cpir12675_002307</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AIM41 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000044">
        <property type="protein sequence ID" value="KAL1897519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1510.10">
        <property type="entry name" value="Uncharacterised protein YqeY/AIM41 PF09424, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023168">
        <property type="entry name" value="GatB_Yqey_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019004">
        <property type="entry name" value="YqeY/Aim41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042184">
        <property type="entry name" value="YqeY/Aim41_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28055">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 41, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28055:SF1">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 41, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09424">
        <property type="entry name" value="YqeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="GatB/YqeY motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="3">
        <location>
            <begin position="100"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU365099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="526" mass="58324" checksum="1ED9645F7A28D48F" modified="2025-10-08" version="1">MLPLHNTMSENPYDPDPYELGAPISPRSDGSPAGSDDSLLDAVLDYAGRDYHVLSVHEHIHYEPIDFDEKYRQACQHKFMCAAFNGSLTYKQLSYMPTSILDCGAGSCTWAISMATMLPNCHVVAIDIAFTLIPDEIPLNLEIKRANLNESLPFDSESFDIVNSRMVVGGVEKRHWVGYLHELKRITKRGGFVQMAEMDYQPYSRSNQVIPEQGLGRWGALYYQTMSRRKDPEITKKLYQMMCNVGFVDIASNIIMAPTCSWPEEAYAKELGHINQSNVQLMLGGTILFSLMFIERLLEDDVRAMQRRAQYDANNHSLQLVQLLVTFLQASYKMLTFATRRSMFASQSSALMRQTAMTMTSQRLYSTATDGPALLSMIKGDLKTAMRAKDAPRLAVLRAIMSATLNASKTASPIKTDVQLIALLRKNVAASKDAAAQFKGAGREDLEAKELGQVAILEAYIANSGVQSVGLEQLKSLIAEKIKEAKAAGAKSLVGEVMKRMNAELEGKDVDKKEVSALVKQMAESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAT7</accession>
    <name>A0ABR3ZAT7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcription factor TFIIIC subunit tfc4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TFC4</name>
        <name evidence="3" type="ORF">Cpir12675_002497</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000049">
        <property type="protein sequence ID" value="KAL1897176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039340">
        <property type="entry name" value="Tfc4/TFIIIC-102/Sfc4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23082:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23082">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIIC TFIIIC , POLYPEPTIDE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="436"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="18"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="65"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="503"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="511"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="527"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="553"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="834" mass="93769" checksum="C1D9C2DE0553F040" modified="2025-10-08" version="1">MDSDDEIDGLMANSNALIESIRNEVEKHENNEQDEDISDADSDMMELENDIEKYNKSVHGFLAAHRGESNTNVTKPQKPKGALRGPRKAAEPRGDIKARLSKANQAFLSGDYLQARNYIFEVIRINAETHQAWTTLASIFREEGLPDKALMSMVYGAHLRPKDVAGWMKVAQFALSMTTDVENALTTARLCYSAALRADSKNIAARVGRAAVCLEQNHVSLAIADYRMVLNQTPLDIDVIRKLADACLDSPNIQTAAPVAIKAYQEFIEFEMGQIDGKHRKYSWNDVIFYTELLSASNQFYEAISEVKRLSRWLLSMPNDPFWRTWTQDDREFDVRNTRRAEVYEGTLALVSYEEDQLPIQLRVRLGTNRLKLGDVEEGLRHLECLHPTTLGAEARAREFPYLIQVAAEQIFDAGMMVRAIPYFELLRQIIGPEDAGVLFHLGQCHVSTGNMEAAEECFLATIEIDESNIEARVELAKMYESAKEGEEALILVTEAIALQNAQRGEEDRNAIAGEGADIGDGPQPKPRSKNTRTPKRRKKASGMIPTRFRPRRLGDPSQRRKAEQERMKGLLEKYGEAQTLRSQIYQGDDSMVYAWAAVAKELIDDFRSSKKFYTWDKYLKLLGRTSEGGEARKEGAKSALDEMAERLTKAVLPQPCEAPEPITTTTDDNYLGIPFEDWLDLFLDYAVCLCHDGQYNESAIVCDGARDSTVFRTSCDFTTRIYLTWGACAAFAGDEEACVSISRNVIRDNPASADAYRMFAIMSRICQSSASWYNSGPAQKFLLRQIKAMDGPLLASSSDSNQGFLESPDVNVLMLYGHILFMSTSYTYALREY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB66</accession>
    <name>A0ABR3ZB66_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_002320</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000044">
        <property type="protein sequence ID" value="KAL1897532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051334">
        <property type="entry name" value="SRPK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634:SF9">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="122"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1897532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="480" mass="53789" checksum="5A1D8E63F13F73F2" modified="2025-10-08" version="1">MPPSVARFGALRMALAHRPAWPLIPHPRYGNHTLAPAQTQTRSLISTATTTPSSAAATAAPAALPSATESAPARNIGLRPYSDSALYAGIASQKPVEEERYAAYDPQSFYPAEIGEVLDGRYRLVSKLGWGTGSTVWMAEHIGASKNRYVALKITNSSPVVQATAEKEFDLTRHMFHTRTKHHGQQYLREMIDAFTVEGATGNHLCMTFEPLRQPLWLLGRQKEPDGVIKPATLKAVMPSILKCLDFLHSECHIIHTDLKADHLMIDFEDSAVLERYVTANDASPAPFIKRRGRRVYESRPDFGPVEHDVTYVKITDFGLSVRGDMGPLNHAIQPVEYCAPEVFLECGWSYPADMFNLGLVMWELLAEINLLDGRHDASSPFSHVVRTAQMIRLMGPPPRELAARASPERRKIMFDKWGAFLYPQLVPDASFSFENQTAMFGMGSEEQRLFINFAKRMLTWLPEERATARELLDDPWLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBM3</accession>
    <name>A0ABR3ZBM3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Pre-mRNA-splicing helicase BRR2</fullName>
            <ecNumber evidence="9">3.6.4.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">brr2</name>
        <name evidence="9" type="ORF">Cpir12675_002090</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000037">
        <property type="protein sequence ID" value="KAL1898071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18019">
        <property type="entry name" value="DEXHc_Brr2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18021">
        <property type="entry name" value="DEXHc_Brr2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.10">
        <property type="entry name" value="Sec63 N-terminal domain-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041094">
        <property type="entry name" value="Brr2_helicase_PWI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048863">
        <property type="entry name" value="BRR2_plug"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050474">
        <property type="entry name" value="Hel308_SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004179">
        <property type="entry name" value="Sec63-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057842">
        <property type="entry name" value="WH_MER3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961:SF4">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961">
        <property type="entry name" value="DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21188">
        <property type="entry name" value="BRR2_plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18149">
        <property type="entry name" value="Helicase_PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02889">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23445">
        <property type="entry name" value="WHD_SNRNP200"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039073">
        <property type="entry name" value="BRR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00973">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158702">
        <property type="entry name" value="Sec63 N-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="533"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="755"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="1384"/>
            <end position="1560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="193"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="224"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1898071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="2201" mass="248991" checksum="7710157E376C84D9" modified="2025-10-08" version="1">MSGANRDVSQYKYSAMSNLVLQADRRFVTRRNDEATGDPESLSGRLKIVDMGSRVLRDSLPKSKKSSMLSSIERGNAQDGRDILEREKRKSKVGSALGRGLSAADIAVEGIQYRPRTIETRETFNLILTIVANNLGDVSYDVVRSAADAVLEYLKDEDMKDFDKKKEIDDILGTSLSPKELNEMINLSKKITDYDAQDDESQTSAMDVDNNDELDDRQGVAVAFDDDDGDEEGGFVDEVRDQSSDDEDAEEDNDQEKSDDKNDENISDDEMLIDSAPAATGSSEKSKETTKSIPAREIDAYWLQRLIGKLYEDPHEQHDKTIEALRILSGEPDEAGGEEKQLREIENDLMELFDFEHHELVNRLIANREKVVWLTRLARADGEEKRLVVEREMASEGLQWILNELHGKGSSEAKLKKEIKMDIDVPNNIISAPVETEKDEGQLVGGLKPRKIVNLENLVFDQGNHLMTNPKVRLPEGSTKRTFKGYEEIHVPPPKKRNDPNDRLIPISELPEWARCPFSTTKSLNRIQSQCFPTAFENDGNMLVCAPTGSGKTNVSMLTILRELGKHRDPSTGVIDLDAFKIVYIAPLKALVQEQVGNFGKRLEPYGITVAELTGDRQLTKQQISETQIIVTTPEKWDVITRKATDLTYTNLVRLIIIDEIHLLHDDRGPVLESIVARTIRKTEQSGEPVRIVGLSATLPNYKDVASFVRADPVTGVFHFDGSFRPCPLRQEFIGVTDRKPIKQLKIMNDVCYNKVIEHVGTNRNQMLIFVHSRKETAKTARYIRDKALELSTINQILRHDAGSREVLKEAADDATDKDLKDLLPQGFGIHHAGMNRMDRSDVEDLFARGAIQVLVCTATLAWGVNLPAHTVIIKGTQVYSPEKGSWVELSPQDVLQMLGRAGRPQFDTYGEGIIITSQSEIQYYLSLMNQQLPIESQLVSRLSDNLNAEVVLGNVRTRDEGVEWLGYTYLFVRMLRSPGLYQVGAEYEDDNALEQKRVDLIHSAALILRKSNLVKYDEKTGKIQSTELGRIASHYYITHDSMETYNALIQPSITVIDFFRIFALSAEFKYIPVRQDEKVELAKLLQTVPIPIKESIEESHTKINVLLQAYISRLKLDGLALVADMVYVTQSAGRILRAVFEITMKKGWSSVAKTALDLCKMAEKRMWPTMSPLRQFPSCPKDVVHKMERIEAPWSAYFNLDPPRMGELLGMPRAGRTVCELVAKFPRLEVQAYAKPITRSLLHVGLSISPNFEWDDNVHGTSEGFWIVVEDCDGEEILFYDQFVLRKDYAVSEDNEHMVDFTVPISDPLPPNYFISVISDRWMHSETRLPISFQKLILPEKFPPHTELLELQPLPVSALKLKEYQGLYPEWAHFNRIQTQTFNSLFTTDQNVLVAAPTGSGKTVCAEFSILHLWSQKDHGRAVYVAPSQDLVDIRLQDWQKRLGGIRGGKEIVKLTGETTRDLKLLEQGDLILATPSQWDVLSRQWRRRKNVQTVELFIADELHLLGGNQGYIYEVIVSRMHFIRTQTELPMRIVGLSVSLANARDIGEWIGAKKHDIYNFSPHVRPIPLELHIQSYSVPHFPSLMLAMAKPTYLSILQLSSSQPAIVFVPSRKQTRATARDILAACLVDDNEDRFLHADPEQLKRILEHIHEEALAEAISHGVGYYHEALSQNDRKIVKHLYDNGAIQVLIASRDVCWELNSTAHLVVVMGTQYFEGREHRYVDYPIAEVLHMFGKALQPSKDGRGRGTLMVPAAKRDYFKKFLNEALPVESHLHNFLNDAFVTEVSTKMIESIDDAINWTTFTYFYRRLLANPSYYALTDTSHDGLSTYISDLVETAINELSEAKIIDFDEEDGSVSPQNAAMIAAYYNISNVTMQTFLMSLKATTKLKGILEIITSATEFESLQSRRHEESLLRKIYNMLPVKMADANAESAHFKAFVLLQAHFSRMQLPIDLSKDQEIILSKALSLLSATVDILSSEGWLNAMNAMEMSQMVVQAMWDRDSPLKQIPHFSPEVIKAANEAGVKDVFDFMEAMNPEDPNYKTLIKRLSLSNSQLVEVAKFTNEKYPDMELEHEVVDADDIQAGEPAYLQVQITRNIEEDDEFDALVHAPFYPAKKMENWWLVVGEEATKTLLAIKRVTVGAELKMKLEFTVPTAGVHKCKLFMMSDSYMGVDQEQEFEVTAAEAIEVDSDEEEDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCM0</accession>
    <name>A0ABR3ZCM0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Vesicle-mediated ER to Golgi transport protein</fullName>
            <ecNumber evidence="7">2.1.1.319</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">USO1_2</name>
        <name evidence="7" type="ORF">Cpir12675_002296</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.319" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000043">
        <property type="protein sequence ID" value="KAL1897568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035242">
        <property type="term" value="F:protein-arginine omega-N asymmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006955">
        <property type="entry name" value="Uso1_p115_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024095">
        <property type="entry name" value="Vesicle_P115"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006953">
        <property type="entry name" value="Vesicle_Uso1_P115_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10013">
        <property type="entry name" value="GENERAL VESICULAR TRANSPORT FACTOR P115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10013:SF0">
        <property type="entry name" value="GENERAL VESICULAR TRANSPORT FACTOR P115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04871">
        <property type="entry name" value="Uso1_p115_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04869">
        <property type="entry name" value="Uso1_p115_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Vesicle tethering protein Uso1/P115-like head" evidence="5">
        <location>
            <begin position="339"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="domain" description="Uso1/p115-like vesicle tethering protein C-terminal" evidence="6">
        <location>
            <begin position="912"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="674"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="753"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="829"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="919"/>
            <end position="1023"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1897568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1029" mass="115283" checksum="902E680607E58D55" modified="2025-10-08" version="1">MFSSISTAPPKQSASETILVLSGRLNSASLLEDRRASILGLRSFAKDFPASVASGALRSLIGSLGRDGEDADTLKIVLETLLMLFSPNESSPEASDEVALWLADEFTQRQQNITLLLDLLESNDFFSRLYSLQLLVAILSARPERTEECIFTAPLGISRLVAVLDDSREAIKSEAISLLIYLTPKSPDLQKLVAFENAYERLFTTIDAEGGLTNGGRVVEDCLILMANLLRQNPSNQTLFRESGFILRLSLLLESSLQQEAEIELAGWVLSQKNRNLYALLALVRLFLMSRAVGTAQNQIAFHQNGLLNSALQLSFNPQTQNQIRAEAMAVCADIIRGNSSLQEGFAQLTVPSPFPPPQPAGTESQTAWPQVYVIDGLLDLTLGLTSLQDFDLRFSACECLKAYFFSHDQIRSHFLGRAIGGYKSGHDETANVLSILLSPTPIDLAASDPYRMWFSATITFHLLYNNPTAKVQGMELTEGEAEHGEEVVTAIQTIMAHLISGLQRSEEPRHLIAYLMLLIAWLYEDLDAVNDFLSEGSNVQGLVQAVIQPRGVDEIVQGLCSMLLGVVYEFSTKDSPIPRPSLHSVLLGRMGQDKFSDRLSRLRAHPSMRDYEVTPQKLDPMSGLLPDVFFDRTFVEFFKDTYSRVSRALDRDPNMEISVISNGVQKGISRELVDSLRHELAEKEKAIEKSRDELASIESALQKEQAEHRKTKDTSSVEVARMKTVNEALQLQNELELKKSDTQSQQEIALTREKLEQVQHKYEDQMRSLAADHAMQLGELRNKIQQLENENAERLRQAEVTRRDIQADFEQQLHKTKVANDSEVERVKARLEAKIADLNATCSRLEVDLMKSRRDHSQEIQLLKASHQEQLKEHQAKADEHLDQEKLKTQQVIIDVRALAEQEIISLKSRLKESEAYVKKAEASSEKAEISLRKAETRAQNAEVSLQRAEIDVKKSKDLIKSLEQNLEEHKLQVASLDDSKKEVQAELDDLLIVFSDLEEKVSDYKTRLANLGQAVSDAEDDDDDEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD92</accession>
    <name>A0ABR3ZD92_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_001862</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000031">
        <property type="protein sequence ID" value="KAL1898658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07722">
        <property type="entry name" value="LACTB2-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047921">
        <property type="entry name" value="LACTB2-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041516">
        <property type="entry name" value="LACTB2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050662">
        <property type="entry name" value="Sec-metab_biosynth-thioest"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23131">
        <property type="entry name" value="ENDORIBONUCLEASE LACTB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23131:SF0">
        <property type="entry name" value="ENDORIBONUCLEASE LACTB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17778">
        <property type="entry name" value="WHD_BLACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="5">
        <location>
            <begin position="34"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1898658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="278" mass="30675" checksum="73045BD7C69832B4" modified="2025-10-08" version="1">MNVSTLPALPDFDRLSERCIRINGGNPGKFTLQGTNTYLIGTGRERILVDTGQGFGKWLQVLKKILAVEKATIRDVLITHWHSDHVGGNKDVLALCPNAKLYKNAPGVGEENLLDGSEFKVEGATVRAYHTPGHTTDHMCFLLLEEDALLTGDNVLGHGTSVYENLAVYMDSLHRMRSIFKGRAYPGHGAVAEDGPALITQYIEHRAKREHEVTQKLQSQSNSWTAMGLVKAIYTTTPPELHEAASKGVQHILVKLEREGKIVAVSGQNESTSWIWVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDA6</accession>
    <name>A0ABR3ZDA6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cell separation during budding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SDS23</name>
        <name evidence="6" type="ORF">Cpir12675_001864</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000031">
        <property type="protein sequence ID" value="KAL1898660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02205">
        <property type="entry name" value="CBS_pair_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050511">
        <property type="entry name" value="AMPK_gamma/SDS23_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780">
        <property type="entry name" value="AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780:SF36">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="237"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="311"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="501"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="520"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1898660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="539" mass="57255" checksum="5667DEF3CE3145DC" modified="2025-10-08" version="1">MDNSSISGKGPNPGHSSGSTETAAAPIPLSASATPQKIPSRQTSAASLRINSGAAASPGASASASAVGSPPAVNIPVLATHRQALAENLYSIPSSPRSARHPSFTQAALQDLVSIQSHAIQRNRKLDPRFADRDWREVAIGELAVADEVKWVTMDTSVQEATNALLKTSPTNAVLIRETETSESAISTFDYNDLNAYLLVIVGIAKPDDETRSMYAEIATKAHKGQALTLVDIQPVCRKESLVALPRGEKLDKAIEVLGSGIHRLLITDDDGNVVGILDQLKIVAFFWKEGINFPAIDSMYSASIQDLGIASKSILAVSQDSHLTEALLLMFNEGLTSVAIVDSVQKVVGNISTVDVRHLTTSSSAHLLQNTCLNFISVILNARGVDQGRDSFPVFYTTNYSTLSHTLAKLVATQSHRMWVVETASPANSNPATPLLLQKTPVAASSSPVLVPTGSATHYSSSPSHVSFLMSAAGSHSHAMSGRLAGVVSLTDILNLFAKTTGMNPADPNEQRAKRRRSSSSSVRPSLDSVRTSLDIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDD2</accession>
    <name>A0ABR3ZDD2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Splicing factor Cactin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_001909</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CACTIN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000033">
        <property type="protein sequence ID" value="KAL1898364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019134">
        <property type="entry name" value="Cactin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018816">
        <property type="entry name" value="Cactin_central"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21737">
        <property type="entry name" value="POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21737:SF4">
        <property type="entry name" value="SPLICING FACTOR CACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10312">
        <property type="entry name" value="Cactin_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09732">
        <property type="entry name" value="CactinC_cactus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01050">
        <property type="entry name" value="CactinC_cactus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Splicing factor cactin central" evidence="5">
        <location>
            <begin position="98"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Splicing factor Cactin C-terminal" evidence="4">
        <location>
            <begin position="406"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="315"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="40"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="77"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="329"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00034534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1898364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="545" mass="62479" checksum="5E8A1A3689DC3D96" modified="2025-10-08" version="1">MNPDRAAMISSRPSAQDGDGDHDDRGSNRRPNRITNYSSRDARRENRPNDRQDRYGRDRRDQDRDLTAPRHDRNNRVSKPSSSTSSRNPTPQHTRYLTQDEQSQQYVADEDKFVLQQAKKKADIRVREDRATPIDNLAFPLRYIEPARDDFDFNEGDVDIDVPEAHTVLDRASPAQLRELKEEILSYRTLEINAVSREYWVALYGLCVDRLASTGSDSRVVESVKADIDKILSPKTFDQLEALEKQIRTKLDSDDDIDVDYWEQLLKSLLVWKSRAKLSKITTAIREARAQALKERDPEKAKALEAGLDLSAISAPLPLNKPDERKSVPLSAPLSAPLSAPKPSSSTDAPPPGTARFAQTGPEDFSSATKALYDREVARGIREDEEIFSTEEAVPDSAGGAMPPIWANKYRPRKPRYFNRVQMGYEWNKYNQTHYDHDNPPPKVVQGYKFNIFYPDLIDKTKAPTFKIIRENGRRRGESSTSTMPGENDTCLIRFIAGPPYEDIAFRIVDREWDYSSKRERGFKSSFDNGILQLHFQFKRIFYRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE97</accession>
    <name>A0ABR3ZE97_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000027">
        <property type="protein sequence ID" value="KAL1898986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="432"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="689"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="758"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1082"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1212"/>
            <end position="1284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1299"/>
            <end position="1444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="141"/>
            <end position="150"/>
        </location>
    </feature>
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            <begin position="250"/>
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            <begin position="302"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="433"/>
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        </location>
    </feature>
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            <begin position="538"/>
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        </location>
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        <location>
            <begin position="585"/>
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    </feature>
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        <location>
            <begin position="599"/>
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    </feature>
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            <begin position="689"/>
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    </feature>
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        </location>
    </feature>
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        <location>
            <begin position="758"/>
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        </location>
    </feature>
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        <location>
            <begin position="791"/>
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        </location>
    </feature>
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        <location>
            <begin position="829"/>
            <end position="838"/>
        </location>
    </feature>
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        <location>
            <begin position="872"/>
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        </location>
    </feature>
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        <location>
            <begin position="902"/>
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        </location>
    </feature>
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        <location>
            <begin position="1105"/>
            <end position="1118"/>
        </location>
    </feature>
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        <location>
            <begin position="1245"/>
            <end position="1279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1322"/>
            <end position="1335"/>
        </location>
    </feature>
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        <location>
            <begin position="1336"/>
            <end position="1351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1352"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1378"/>
            <end position="1397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1402"/>
            <end position="1422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1426"/>
            <end position="1436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1444" mass="152158" checksum="B1D1D4952F6E65C7" modified="2025-10-08" version="1">MMAATTTATNKSVDADDYNNSRAVACSSQHMQTHTLASASAEPGLSCSSVSSSSSSSITNNEPPSSISDTAIAATVEEHRKQQISHSHAPALQKQSAKDSADAQPSQRQPPVTTTTTTSVTDGSDSESLTLASSTNIPKQDATKKPDRASSLKKATTFKAVSVNKTFLAAKSAMSASQLKTNDKSAPSSAASTPPNSSTLPATRPRLIAKTGGSGPLPKFAGINSGRSSVTPEPAGVWNKNPPPPPPPATTTSSTSTTQATATATPLVDHSKLTDEELKKHGIHVANRLHTDDSKTSHNDWADIEDDDDEWAVPDSITWTDGTKTTLPPADEVLQSPTLSPPASPSPSKHQPDTPAAANVNTVPSTGARYSARASGATPYVPGTANKPGLILRNTGDKPSLIAKAPPAAAPAKSPWATLPAVDRASPVVPFVSSPQQSQRNIHGQHQGYNSNSNNRMAPPQDSYQSRNFDSSMDKRAGGDYGGHQDYMVQRSRQTTTSQDYKHSSGYPPRQMPNEGPYSRSRSGSSNMGHGPDRFHHMNNNSPSSNYHNPDSSHLGRYAAPRRPSFNNGPLPFSHGRQHGLISASGRSASGDYTSANGPEGGGANSHGGSSHGGLPPHGAMASTSDMARPLEPNNIQSQRPMIYRGHNPSPNNIEVDGSAIALPVEIPEEETAEFQKKLMRERAEEAMRRRQEEERREEAAKQERLRLKLEALGPAPERQSTKKQTPVSSSVQPSTADAVTTALETVPVPVALQARLRDQVPADRNKPQDAAYPVLPSEQPVPNKVALDASNDTPTHTSKQPRVWESSGVSPNAQIAGPPPSRDLATASWGSGSNAQAPRNVWGAPNNDRGLGNGTFITDMSGLASVTPNKTTSGPTPIGPPSSSSNTRVTSSVWSAATPDAEGRGIRESRSGSKFHSIEKTGTVNAEHHHPHSHPSAILKPAWRSAAEAEASCDFKPTSVESSAVPVQSRTSRFFPTCDPQPTQSPAYATALSTSSIGPVVEQPGIRIKSPSPPPPIAEDHPVYDGNPSHPMVSFPKPQPVVKLPPALDGSASTLASGRALAAPPSASGHWQDKINSLLSGHKPQHHRESFDHGSPQIHHSRPVSRNSGASHSAHNSLASPLPQIAELPTTMPMSTECFEEPEMGSLPSIHIPKDVPEAAWNPATPQTKQLPRRFTIIHNTSAGNPDFYEPSGQIRISLAGMSDPRFVFHASARSSRTQSRGSGGPSRSRRGGNRGHRQEQGHSSASNSTTTYASVSASVSAPPVPAVDSTSVPAASTPKSGPPLTIAAVVAASLAKPHPGHPTASSVLASKSAHPGSEDSAVTASASTPVSHSQVQAPAQTKTHNNQPETSRRATRFNEETSMAKEANGGGHHRREREPRSARGLKESRGSKDSGGHGQGQARSQSQGQGQGQGRPPRGGYKNRGAEWGRREVATSRSQTTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZES2</accession>
    <name>A0ABR3ZES2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001799</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000030">
        <property type="protein sequence ID" value="KAL1898692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052258">
        <property type="entry name" value="Diverse_Func_Domain-Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37612">
        <property type="entry name" value="FIBROIN HEAVY CHAIN FIB-H LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37612:SF20">
        <property type="entry name" value="PER-HEXAMER REPEAT PROTEIN 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045483592" evidence="2">
        <location>
            <begin position="17"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="155"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="304"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="394"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="471"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="530"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="609" mass="56641" checksum="A307ABBE9E08DB86" modified="2025-10-08" version="1">MKASVATLLFAAVVSASPRFQDRSLRPGQDYYGAPAVSSASSSSSAAASAYSAPPSAPEEEPVYGNPRADASSSVPGAQTPSIVPTGDVISKFSPLSGTSSSLTPGATGTGNYPIQSAGSASSVPAITAASSSSSTPLAAGTGSYGVPINSANSTSSVDAVGSSSSAPSSYGTAPLTTAPLTTAPYGTAPQGTGPHGTAPMNTASTGYGSSPTQSGNFTFINTRTAGRQQTTLTVVTTQLVTVTSCAPTVTNCPSRPEDIPLGDQEVKVITQIVPLYTTICPVTEVPAIASSVMQGGSGKGLATSGSSLPVSSVSPVGGSGTGSGSGTGSGSGTGSGSGTGSGSGTGSGGYNTDTSYGSDRSSNKETPDETTIIRGTRTATQVLTVPTTVEKNSPVSPSDGPGSGSVSDTDTGSGSGSGSGSGSGYGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGYGAGSGSGSGSGPGSDSCTCPPGSGATATVTVTSPPQTVYVTVGAGATGAGSGSGSGSGSGSGSGSGSGSGSGSVTSDFAAVPTGPSGTDSDSDSCPAEEVVTATATVRVTGTGGLPAGTGLAGTGTGTGGIPYATGTGAPYPVVNGTNTSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFC7</accession>
    <name>A0ABR3ZFC7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_001662</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000027">
        <property type="protein sequence ID" value="KAL1899002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901:SF1">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1899002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="272" mass="29110" checksum="1C2CBBA1DF6A02C9" modified="2025-10-08" version="1">MSLAAAAKRIVGKTILVTGASSGIGKSTALEFARNAPNNLKLILTARRVENLNELATQIKSEVGDGVKVLAVKLDISNPAEVRQFVPNLPEEFKEIDVLVNNAGLVKGVACAPDIDEEDINIMFQTNVTGLINMTQAILPIFKKRPDGGVGDIVNVGSIAGREPYSGGSIYCATKAAVRSFSDSLRKELISSRIRVIEIDPGQVETEFSIVRFYGDKSKADAVYNGMDPLTPGDIAEVIVFAVSRRQNVVLADALIFPSHQGGAGVIYRKPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG41</accession>
    <name>A0ABR3ZG41_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001269</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000019">
        <property type="protein sequence ID" value="KAL1899688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="1">
        <location>
            <begin position="168"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="314" mass="34008" checksum="CE40A15D00F4FDB6" modified="2025-10-08" version="1">MTLSDNNQLAINAIARIGGNRRSRFDPWNSPSTGHQVAETRPGTGWRESRQTKLCSQLKSGSGGGVRMKDMYGQGAADYDEKLNMIVPREVRIQARTTVADMIVKPGVMRKTLEPEMVPGPGIGRLGNDVLGLGPPPSRGVPEAHPNQMEDALKPAPGQQDMSTTAPAQKGIFYGLVVYINGSMQPEISDLKLKRIFAEQGATVSLHLARRQVTHVVLGRNATVGRGAGGGLAGSKINKEIHKVGGNSVKYVNVEWLYPQFYRDLLTMGVQGTGKPQGWQETVRGSFLECQSGTPGPEERLLNVSETKMNGSYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGC3</accession>
    <name>A0ABR3ZGC3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">cAMP-dependent protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">TPK2_1</name>
        <name evidence="13" type="ORF">Cpir12675_001230</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.11" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000018">
        <property type="protein sequence ID" value="KAL1899731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05580">
        <property type="entry name" value="STKc_PKA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF153">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="404"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="12">
        <location>
            <begin position="660"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="159"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="292"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="17"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="65"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="159"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="216"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="234"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="262"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="311"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="362"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="433"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1899731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="715" mass="78863" checksum="86CBC779B4BA2D40" modified="2025-10-08" version="1">MPSLGFLKKKRTRDGQSDSNSGSQPTSPVSPNGTTKRFGSQSIANILSSHLPSSHHSSHSHSHTHLPSTSASNSSTGPVTSGSSVTSPLVSPTLPPAAASPVTASAPATAAATAHTNTNTNNSASTNPSTTDPIPQSKSDLQLALAQPQLAAEQVNNTGSVDVNMNSGTGAASNGTTPTQAFPASHPNTNGGTVPQQNVQAPMARSGQGGEPNGLPSISISNLINPTNDNCGSQQHQQQQAHHEQYSQQPQPQAIPYGDHSQQQQQQQQQQNTQQTGFIEPAEDTLIIQSNVQPQQQAHTQPQPPQMMQQQHHHHHHHNHHQQQTGQVGQPIPMPQQQQQPSAHCMISAPQVPAHHTQGTSQQQQQQQQQIPQQSQQPQAQAQQQPAVVSEARVTKGKYTLQDFEIQRTLGTGSFGRVHLVQSKHNTRFYAIKVLKKAQVVRMKQVEHTNDERKMLGEVKHPFLITLWGTFQDPKNLYMVMDFVEGGELFSLLRKSGRFPNPVAKFYAAEVVLALEYLHSRNIIYRDLKPENLLLDRHGHLKITDFGFAKRVPDKTWTLCGTPDYLAPEVVSSKGYNKSVDWWSLGILIYEMLCGYTPFWDSGSPMKIYENILRGTVNYPVYVNSDARDLLERLITANLTKRLGNLYGGSQDVKEHRWFAEVTWDRLARKDIDAPYIPPVKAGAGDASQFDRYPEEQERYGTDGLDEYGHMFPDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHQ8</accession>
    <name>A0ABR3ZHQ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aromatic amino acid beta-eliminating lyase/threonine aldolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_001282</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000019">
        <property type="protein sequence ID" value="KAL1899699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023603">
        <property type="entry name" value="Low_specificity_L-TA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097:SF9">
        <property type="entry name" value="L-THREONINE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097">
        <property type="entry name" value="L-THREONINE ALDOLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017617">
        <property type="entry name" value="Thr_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aromatic amino acid beta-eliminating lyase/threonine aldolase" evidence="5">
        <location>
            <begin position="1"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="328"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="349" mass="37435" checksum="F2E170AF568406F4" modified="2025-10-08" version="1">MLEAIQNCTLQDDVMQEDATTNNLEQQLAELTGKEAGLFTLSGTMGNQLAMRALLTQPPYAVLSDSRSHIVMYEAGSASSLSGAMMVRVTPSNGMHLTLEDIIPHVTLGDDIHTCPTRVISLENTLDGLIFPPSEISRIAAYASEHSIKLHCDGARLWEAVAAGSGTLRELCTPFDTVTMCFSKGLGAPAGSILVGSASAIKHARWTRKAIGGGVRQPGLLTAAARVAVDTTFGVGSGGEGGKLKAVHEVARKVESLWAGFGGKVTCPVHTNMVWLDLAAAGCSDARFVGLMEAEQLKAFGPRLVVHYQVVEMSEQVLEKLERVFRRATDRSESDPDTRKGQKNMYKLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI97</accession>
    <name>A0ABR3ZI97_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Sexual differentiation process protein isp4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_000973</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000013">
        <property type="protein sequence ID" value="KAL1900391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="229"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="293"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="320"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="421"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="473"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="499"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="583"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="649"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="728"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1900391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="793" mass="88592" checksum="496A981AC95692B7" modified="2025-10-08" version="1">MGFSLRRQQAGEPVVEDDAVASTSSLDAPDRLARVRNISKWDPFLDFETLDKVGETLQSGDVEKETAVRQTLYEDNSPYAEVRAAVPNTDDPDTPCSTIRAWVIGGLLCTIVAACNILLGLRRSPIVISATVVQLICYPIGVAWGKFMPNYDFHLFGEVIPLNPGDFTVKEHTVITIMTAAGATSSYAIDILLAQEIFYNQYFGWGFQILLILSTQAMGFGLAGVLRRFLIWPASMVWPSTLIFTTVMFSLHDHAPSDPSLTNGWAIGRYTFFIVVATCTFVYEWIPQVFAQFLQIFTFATWIAPNNVVVNQLLGGQTGLGLIPISFDWSIISGFLLSPLQTPAFAIWNVAFGIFMMLLGCIGLAYAGPEYMKYLPISANRNFDHFAQPYNTSRILTSTFEFNETAYQEYSPLLLGPAFSLSYGMGFAGLVSTVVHVALFYGQDIIARTQDLKYEPPDVHLKLMRKYKEAPEWWFMSIFALSFTFGMVASQAWSTHLPWWAYIVCILIAVFFILPVGIIQAITNQQTGLNVITEMIIGYMLPGRPIAMMLFKSWGYMTCYNGLAYVSDMKIGHYMKIPPRTMFAAQAFAVIWLSFVQIATYNFLRDNVNGICTTTQAQGLTCPGSRTFYNASVIWGVIGPKRIFGAGAIYGWTNWMWLVGSVLPVAQYFLARRYPHSPLRYVFWPAIFGAAGMIPPATTWYLAQWCIVGLIFNSFIRNHWNGWWIRYNYVLSAALDIGTAICIIFVALGLGLGNADFPEWWGNTVFNNNLDANEAAVSKTLPDDGSFIGPSSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIY8</accession>
    <name>A0ABR3ZIY8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RNA-binding S4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_001131</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_uS4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="30S 40S RIBOSOMAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF4">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US4M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="RNA-binding S4" evidence="8">
        <location>
            <begin position="181"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="241"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="246"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="263"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="290"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="520" mass="59496" checksum="ECF5A36B073DE5D4" modified="2025-10-08" version="1">MRAAVKRYLISNPKLRQSWNKFNLYNLSKYSATIPRANRTFFQQKWQAKKALRSYHGEHIGEKRWTRLFSRQLMGAIEMPPEYLAAHDGSEQAAGRGSGLETDPNDPRAQPTVTASNFSKIEQIRLAKEEQEQALANQGKLNWPSPFVRNRQTRDRPGALLAKPIHKMTPYMHMTFAPMERRLDIAMFRAMFASSPRQARQFCIHGGVTVNGKKMRYGAYLLNPGDMFQVDPDKVMYATGQPKSKMQAELHAKSQPKRKDASESEEGEIEEESAEGATEKEASDEAESPKPTSIANAMASQKKTISDKKEWFILRRLLASAKALQSRETDLSGKDKQELREFMKQARRAISRTTEAAEEDLMVQKLSALIGRFKIRDMELIKVEKPSATDSGAANDKRSTGYFKPKYNPFELLSPDMKKRSEQLARDNELSLDEQQTLARLMRDAEKNPVDPSKPYATPWKPRKYLAPFAFIPRYLEVNQNICAAIYLRHPVARCGLSEVPTPFPYEFSQLAFNWYLRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ82</accession>
    <name>A0ABR3ZJ82_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Amino acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">DIP5</name>
        <name evidence="10" type="ORF">Cpir12675_000789</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004762">
        <property type="entry name" value="Amino_acid_permease_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00913">
        <property type="entry name" value="2A0310"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF9">
        <property type="entry name" value="DICARBOXYLIC AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="378"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="407"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="450"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="483"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="9">
        <location>
            <begin position="43"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1900775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="558" mass="61447" checksum="2FACCEA369C4B939" modified="2025-10-08" version="1">MGEIHTSAAQAPSISGEKTQTSNIRGLETSDDTKLERGLKARHITMIAIGGAVGTGLIIGTGRSLATAGPGSIFISYSMMGVLVYTVMCGLGEMATWLPMSAGFTGYASRFCHPSLGFALGWCYWFKYIIVTPNQLTAASLVIQYWVDRDKVNPGIFIAIFLVVIVCINYFGIRFFGEFEFWLSSFKVITILSLIMMSFILVLGGGPDHDRKGFRYWDDPGAFATYKDIPGNTGRFVAFWSTMINAVFAYLGTELVGVTVGEAQNPRRTIPRAIRLTFWRIVVFYILSVLLIGCLVPYNSPELAFANKSSSSAAASPFVVAIKLAGIDVLPDIVNASILVFVFSASNSDLYIASRTLYALASDGNAPAIFKRTDKSGVPIYALGLSAFISCLAFMNVSDDSKKIFNYLVNLVTIFGLLTWISILITHIYFVKGRIAQGLTNDQMPYVAPFGLWGSYIALFLCIIVAITKNFTAFIGGFDKINFITGYIGIPIYIIGFFGHRWYTKSKFIPSDQIDFYTGKDIIDKEEEEFLAQQEADEAANPPTGMAKFYAKYVSWVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ98</accession>
    <name>A0ABR3ZJ98_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein ccc1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CCC1</name>
        <name evidence="7" type="ORF">Cpir12675_000797</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CCC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02435">
        <property type="entry name" value="CCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008217">
        <property type="entry name" value="Ccc1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31851">
        <property type="entry name" value="FE(2+)/MN(2+) TRANSPORTER PCL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01988">
        <property type="entry name" value="VIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1900783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="295" mass="31649" checksum="D982F454F8645D48" modified="2025-10-08" version="1">MPSEHTPLLGSSIAIPTHGDVESGAYVAPPVLARTSSSVISSSETSTLNPSSSSSSFSGNNYVLRDIIIGFSDGLTVPFSLTAGLSSLGSTKLVIMGGLAELFSGMISMGLGAYLAASTEHDHYVSEERREYWEVQHKPGEEREEIFDILGSYGVSREAATSVVEALCKDHHAWVRFMMDYELKMERPNTSRAWISGLTMGLSYFIGGLIPMLPYFFMAVAHHALWVSVGITMVVLLMFGYVKNVMTLGSARAGAYGAVQTLAIGMAAAGASYVIVRLLDYSGDGKTGTPNMSMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJB5</accession>
    <name>A0ABR3ZJB5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_000676</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1900803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="138" mass="14823" checksum="44585DD3A2BC8CA6" modified="2025-10-08" version="1">MCGPDNSTRPRVGALAALRPAPGIMDCTECDLIFYTPGSPCSLMATHLRMESKNLLSEKDIRVIIHETGELHKTVDQCGLLVDYSLGKQHTLTQDDASEFVLPQPCSLAIGGQGIIGRRVSLMLNDCPVAEGIIGVNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJJ3</accession>
    <name>A0ABR3ZJJ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Spindle pole body component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_001103</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
            <location evidence="1 6">Cytoskeleton</location>
            <location evidence="1 6">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the TUBGCP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1899998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF27">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4 6" id="KW-0493">Microtubule</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="9">
        <location>
            <begin position="2"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="8">
        <location>
            <begin position="453"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="13"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="570"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="13"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="570"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="601"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1899998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="828" mass="91345" checksum="779B5D930EEF4CB5" modified="2025-10-08" version="1">MLHEILLSLAGNPSPLLTPSSSDPGSASSTTNGNTMERIANAASISAPERQLIANCAELSELNTKLQSYSGQVRSTHPSMICRAAATAIEVEHLREFQRCILKVEQSILSGDSSLVGACRAVPLTAIIGEFSAWTRRLQWLWEIVQFILRVDEGKPCAGARLVDWLRKEMQTGYEDIETAAIGLVKAAEMAWLKQAAAWILYGRLPGFGVTDFFIQRTPAEEFALAPDLLPRFVTPSAASSMLFVGRALNHPKVRTTIESGPVGRQLLSIQLTELSKLSYPINKEHFSRTINCVRLALSKGVLQKLLPLEQVCSTVMLFREFFLLGRGEFAMILTHEADEKNRSRWRRADNLAYEKRDTLGNVIVKQGEVTRVLGRVWATLGSMQGLHADEDEELELARELIRLELTKSKPQTPLKLAARASSKSTSTTIADTPFRNLLFAVPTMLTIPEILSPLDMFLAPSDVQIYSAINSYLLSIKRAHLRLTDLWKATALRRHHPAPPGPPGGSSGFGSVQVKLLRQRQQTRSLAMRSAWVTCSAAVFFLSETEAYLQSEIVAGLWENFHSWLVSSSPNHPSGLSNDKPQKTRNPRHSGAASDSDGVGLDEEQEDPHDDVEGDGDIWLHEMPTIPESRNDMDSRHSGSWPASKRGGHRYATSTLDPQSISVAHRVYLRALAKSLFLTQSSFTDSLYNLLVNVDQLVALIHSLQEIWASIDLEEDAGVVDAFVDLGKEEKDTRRNLRAVEEVVKRSTQDVVAALRALEADSSFMADIEGDTAAATTMDGEGDVVEETEYVPLRVGGISHLLMKLDFGTWFGGGSNDDGLQEQAMMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJM5</accession>
    <name>A0ABR3ZJM5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Bifunctional cytochrome P450/NADPH--P450 reductase</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="14">Cytochrome P450</fullName>
                <ecNumber evidence="14">1.14.14.1</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="14">NADPH--cytochrome P450 reductase</fullName>
                <ecNumber evidence="14">1.6.2.4</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Cpir12675_001133</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>2 oxidized [cytochrome P450] + NADPH = 2 reduced [cytochrome P450] + NADP(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24040"/>
            <dbReference type="Rhea" id="RHEA-COMP:14627"/>
            <dbReference type="Rhea" id="RHEA-COMP:14628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:55376"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="1.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>an organic molecule + reduced [NADPH--hemoprotein reductase] + O2 = an alcohol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17149"/>
            <dbReference type="Rhea" id="RHEA-COMP:11964"/>
            <dbReference type="Rhea" id="RHEA-COMP:11965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:142491"/>
            <dbReference type="EC" id="1.14.14.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <cofactor evidence="14">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">In the N-terminal section; belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.14.1" evidence="14"/>
    <dbReference type="EC" id="1.6.2.4" evidence="14"/>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06206">
        <property type="entry name" value="bifunctional_CYPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11068">
        <property type="entry name" value="CYP120A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023206">
        <property type="entry name" value="Bifunctional_P450_P450_red"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF127">
        <property type="entry name" value="BIFUNCTIONAL CYTOCHROME P450_NADPH--P450 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000209">
        <property type="entry name" value="Bifunctional_P450_P450R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 14" id="KW-0274">FAD</keyword>
    <keyword evidence="5 14" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 14" id="KW-0288">FMN</keyword>
    <keyword evidence="4 14" id="KW-0349">Heme</keyword>
    <keyword evidence="12 14" id="KW-0408">Iron</keyword>
    <keyword evidence="7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 14" id="KW-0521">NADP</keyword>
    <keyword evidence="11 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="16">
        <location>
            <begin position="528"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="17">
        <location>
            <begin position="710"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="492"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="496"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR000209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1900028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1101" mass="121344" checksum="69139507E9AE7CA1" modified="2025-10-08" version="1">MESFASLISAAISSYGAPDEDKSNSMELPIPGPTGLPLVGNASEFSQGPPLENVLRMADIYGPIFRFKIGSSSRVVVSSRELVHDCCDQSRFQKSVKGALSQVRNGVHDGLFTAKAYEPRWGVAHRILIPAFGPVSMQGMFDDMHDIASQLVLKWARNGPQVSIPVTDDFTRLTLDTLALCSMDFRFNSYYSDALHPFVNAMGDFLVECGQRHSRLGVVQMLQRSAEKKYREDINLMQKTAHDVLKYRRENPSDRKDLLTAMLDGVDPKTGLKMDDDSIVDNLITFLIAGHETTSGLLSFAFYEILKNPETYQKAQAEVDAVIGREPISLHHITKLPYIAAILRETLRLDSPIPGFPLECIEETLIAEKYRVYPNEVITCILNGVHCDPVVYGPDPLAFRPERMLDAEFEQRLKDYPDCWKPFGNGMRACIGRPFAWQEVLLCTAMILQNFNLVMNDPSYMLQLQHSLTVKPKDFHMRAILRHGLTATELEKSLHGKTTASQGAKPTGNMGSTSASNEANSGARGRPMSIFYGSNSGTCEAMANRLAADAASHGFRATTVDVLDAAKEKLPQDHPIVIITASYEGQPTDNAAAFVAWLEAVKGQEAQGVEYAVYACGHRDWVQTFHRIPKLIDEVLEARGGTRLVAMGSTDASDRDMFSDFESWEDSTLWPALVQKYKNAGDDQIDMASSALPPGLDVKISHPRTENLYQEVKESIVIDAQELATGKFPKKHIEIKLPSGVTYRAGDYLAVLPHNPAETVSRAVRAFSLNADAYITISGKIQTHLPVGKELPIGSVLSAYIELAQPATKRNITSLAKAATDPAEAVILTSLASEEKYATEITQKRMSILDLLEAYPSIDLPFASFLEMMPPVRVRLYSISSSPLWNPHHVTLTYSLLDEPSLSGHGRHIGTATNYLSSLRVGDRLHVAVRPSPSAFHLPEGPESVPIICIAAGSGIAPFRGFMQERATQVAAGRALAPALLYFGCRSPTSDDLYAEELAEWEAAGVVTVKRAYSRETDKSNGLKYVQHLLYADRAKALALWRDGAKVFVCGSGRMGKAVEETAIQIMLESAKEKGKNLLEEEAREKFAAMRNVRYATDVFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKA4</accession>
    <name>A0ABR3ZKA4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein mL46</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_000695</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL46 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04661">
        <property type="entry name" value="NUDIX_MRP_L46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040008">
        <property type="entry name" value="Ribosomal_mL46"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021757">
        <property type="entry name" value="Ribosomal_mL46_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033650">
        <property type="entry name" value="Ribosomal_mL46_NUDIX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13124">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L46, MITOCHONDRIAL PRECURSOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13124:SF12">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11788">
        <property type="entry name" value="MRP-L46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Large ribosomal subunit protein mL46 N-terminal" evidence="9">
        <location>
            <begin position="59"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="171"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF11788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1900819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="321" mass="35981" checksum="8912A06AAF24EE35" modified="2025-10-08" version="1">MACNRSLAISATLRRTQCLPQMPRGISIRTYAATTTATTTADSTPLPSTTAPTATPSHAIKAGIILTRAPLLTAEPTAFESAFWFYQKRLNERLSLPFSQRFYFKPDTPAQLDWAIKLRERDGLVAREVGKYNGKSANSWNDELLVGDTLSAPETLTQTLLKDAELRVSEDAEEITEEDRQPVESPQPRLSEADHKGDVRRLDRKMDRTLYLTVQQKDGTWEFPAVELEKEENLHLAAKRAMDSSAGLNMNTWIVGRVPVAHIVQPATKTFFLKGRIMAGQANLSGNPLGLKDFKWLTREELETTLAPEYFKGVRNMMADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKE2</accession>
    <name>A0ABR3ZKE2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Eukaryotic translation initiation factor eIF-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SUI1</name>
        <name evidence="5" type="ORF">Cpir12675_000569</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SUI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11566">
        <property type="entry name" value="eIF1_SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.780.10">
        <property type="entry name" value="SUI1-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001950">
        <property type="entry name" value="SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036877">
        <property type="entry name" value="SUI1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005874">
        <property type="entry name" value="SUI1_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01160">
        <property type="entry name" value="SUI1_MOF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10388">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01253">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004499">
        <property type="entry name" value="SUI1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55159">
        <property type="entry name" value="eIF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50296">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SUI1" evidence="4">
        <location>
            <begin position="29"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1901203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="114" mass="12989" checksum="6FF83AD7E88C0C8C" modified="2025-10-08" version="1">MSIENLKTYDPFAEADEDTGETKATQNYIHIRIQQRNGRKTLTTVQGLPSQFDRKKILKVIKKKFACNGTIVHDVEMGDVIQLQGDQRNDVRSFLIDKTDGLELNPNSIKIHGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKG1</accession>
    <name>A0ABR3ZKG1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CHCH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_000584</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010625">
        <property type="entry name" value="CHCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055304">
        <property type="entry name" value="CHCHD2/10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009069">
        <property type="entry name" value="Cys_alpha_HP_mot_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13523:SF2">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13523">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2/NUR77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06747">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47072">
        <property type="entry name" value="Cysteine alpha-hairpin motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHCH" evidence="3">
        <location>
            <begin position="122"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="29"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="160" mass="15732" checksum="47A5142FF993DACF" modified="2025-10-08" version="1">MPRQRSSVGRAPARPTLSKPAATPSAQQSRPAATYAPAAPPARTAAPSAAAAPTSSGPGLFSQMASTAAGVAVGSSIGHVIGGMFTGGGNSTESSALDASPQAAAATSAPAAYNAQTQAGNCGPAAQQFTKCLDEHGGNMQICNWYLDQLKACQAAAAPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKU1</accession>
    <name>A0ABR3ZKU1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Dephospho-CoA kinase cab5</fullName>
            <ecNumber evidence="5">2.7.1.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CAB5</name>
        <name evidence="5" type="ORF">Cpir12675_000533</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.24" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004140">
        <property type="term" value="F:dephospho-CoA kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02022">
        <property type="entry name" value="DPCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00376">
        <property type="entry name" value="Dephospho_CoA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001977">
        <property type="entry name" value="Depp_CoAkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00152">
        <property type="entry name" value="dephospho-CoA kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10695:SF46">
        <property type="entry name" value="BIFUNCTIONAL COENZYME A SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10695">
        <property type="entry name" value="DEPHOSPHO-COA KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01121">
        <property type="entry name" value="CoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51219">
        <property type="entry name" value="DPCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1901300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="274" mass="30358" checksum="E95C47F6D06F4973" modified="2025-10-08" version="1">MLLIGLTGSIATGKSTVSSILSKPPYCIPVVDADILARKVVEPGSKGYAAIVKYFGPTTPDLLVPIADGMPENGPEGEGRPLNRPALGRRVFGDSEERKRDRGVLNKIVHPAVRTEVYRAMFWYYLTGHWAVILDVPLLFESGLDQLCGTVVVVVVSDPEVQMNRLMERDSHLTRKDAENRVRSQVDVRVKAKRCTERGKGRGVVLCNDGTREELEKNIGEAISSLKASSPYWWSYSLLACPPLGLIVGVYGFLQNVRLNRKWAKLEKEVIAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLU4</accession>
    <name>A0ABR3ZLU4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">NADH-ubiquinone oxidoreductase 29.9 kDa subunit mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_000326</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I NDUFA5 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006806">
        <property type="entry name" value="NDUFA5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12653:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12653">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-B SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04716">
        <property type="entry name" value="ETC_C1_NDUFA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="236" mass="26612" checksum="63547E5D08D09CF4" modified="2025-10-08" version="1">MRPTTRLLARYLEPGTQTGLTGLWTHPTPRSTLLFLYHRTLERLSALPASSLYRQSVEAVTKHRLALVEKQVPLGYAEWAERARKTMTERPGQYRLPSGSNDGGFAHTVKYSDKTFVLGKVVSEPDVRVQEWDGEADEGPTLEGIRTPEERADQALIATRKVIDKATTSVELEPEPLLTADQIAELENQIGAGLIEEVIQVAEGELKALDIMEQAKVWESLEEQPAEDQWKYFERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLU5</accession>
    <name>A0ABR3ZLU5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">inorganic diphosphatase</fullName>
            <ecNumber evidence="3">3.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">IPP1</name>
        <name evidence="7" type="ORF">Cpir12675_000365</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00412">
        <property type="entry name" value="pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.80.10">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008162">
        <property type="entry name" value="Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036649">
        <property type="entry name" value="Pyrophosphatase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10286">
        <property type="entry name" value="INORGANIC PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00719">
        <property type="entry name" value="Pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50324">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00387">
        <property type="entry name" value="PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="290" mass="32553" checksum="1394C654BF91A4F4" modified="2025-10-08" version="1">MASPYSVHKVGAANTLEHRVYIKKETQIVSPFHDIPLYANAEKTILNMVVEIPRWTNAKQEISKDEPLNPIKQDIKKGKLRFVRNCFPHKGYLWNYGAFPQTWEDPTVAHPETKAKGDNDPLDVCEIGELVGYTGQVKQVKVLGVMALLDEDETDWKVIVIDINDPLASKLNDVEDVERHLPGLLRATNEWFRIYKIPDGKPENSFAFTGECKNKAYAMDVVRECNEAWERLIQGKVQQPSVLTTNLSVSGTPGNITSAEMPAIPAHQELTPAKIDPSIDKWFFISGASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMB9</accession>
    <name>A0ABR3ZMB9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">D-lactate dehydratase</fullName>
            <ecNumber evidence="1">4.2.1.130</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_000304</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>methylglyoxal + H2O = (R)-lactate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27754"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:17158"/>
            <dbReference type="EC" id="4.2.1.130"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase C56 family. HSP31-like subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.130" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03141">
        <property type="entry name" value="GATase1_Hsp31_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050325">
        <property type="entry name" value="Prot/Nucl_acid_deglycase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094:SF11">
        <property type="entry name" value="GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094">
        <property type="entry name" value="PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="DJ-1/PfpI" evidence="6">
        <location>
            <begin position="92"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="229" mass="24500" checksum="7B38E5BB8111713B" modified="2025-10-08" version="1">MAPKVLVVLTSYSKIEAMDRETGWFLPELAHPYDELKGKAEMVFASPKGGVAPLDPGSIKAFESDASSQDFLKNHKDLWENTQKLSTFVGRSSEFDAIFYPGGHGPMFDLATDPDSIALIAEFHNAGKLIAAVCHAPGVLVNVKGANGEYIVKGKTVTGFSNSEEDTAGYTPYMPFMLETDIQAVSGAEYVKAEKDWDAKVVVSGNIITGQNPASAKPLGEALVKALGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMX8</accession>
    <name>A0ABR3ZMX8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chitin biosynthesis protein CHS5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_000284</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17742">
        <property type="entry name" value="BRCT_CHS5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13945">
        <property type="entry name" value="Chs5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.120.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031673">
        <property type="entry name" value="Chs5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052827">
        <property type="entry name" value="CHS_Export/Cell_Fusion_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031669">
        <property type="entry name" value="Fn3_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47351">
        <property type="entry name" value="CHITIN BIOSYNTHESIS PROTEIN CHS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47351:SF1">
        <property type="entry name" value="CHITIN BIOSYNTHESIS PROTEIN CHS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16892">
        <property type="entry name" value="CHS5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16893">
        <property type="entry name" value="fn3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12738">
        <property type="entry name" value="PTCB-BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="75"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="163"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="313"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="393" mass="41823" checksum="3E4FAC74BD753F51" modified="2025-10-08" version="1">MLVSLTVGKVDAGVTVLLTPDKRLIEFPSILLPPGISSGSIVDITVSRNTGSESASDKAFQSLQDRIYSCFGASEPTTPVLRCRNATQTSVVLEWDPIYLATAELVSLSLFRNGQKAGNIPRPLQMHSTKISGLAVDTAYTFHLVLRTTAGTYSSQQVTVRTHKMTDLSGITITAGAMPPNFREALTAAVERIGAKLVDSVRIDTTHFVTTEGRGVAWEKAVENNIPVVRPEWVEACERSGRILGVTKFYLDAVRTGPPMGSTPSAATQQHTQSNRSSMGPASTSGVSTSASPAPSSSHKPLPQEPSSENKDTTTAANAATPAEANSDSGRDEERDEVRKSRSESSAPSDDDGSKRSSSSSRQNLAVRPAPTIEDTDEDKTGSGRTSFQNIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN37</accession>
    <name>A0ABR3ZN37_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_000213</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052234">
        <property type="entry name" value="U5_snRNP_Component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44006">
        <property type="entry name" value="U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44006:SF1">
        <property type="entry name" value="U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="61"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="104"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="146"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="188"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="230"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="292"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="322"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1902103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="357" mass="38456" checksum="E01A1B8339714159" modified="2025-10-08" version="1">MASEKRPASDDPASFQLVKRPNLGDSSTTGAIARFNASVGGDAMVQTTLRTSGLQAPVMQLSGHTGEIFAASFDPNGNYIASAGMDRNILLWRTYGDCENYGILNGHKGAILDLCWSRDSRALFSASADMFIASWDLESGSRIRRYVGHEEVINAMDISKRGDEVLVSGSDDGTIGIWDPRVKSAVDYIGTDFPVTAVAISEAGNEIYSGGIDNDILVWDVRKKAPLYSLLGHTDTITSLRISPDSQTMLSNSMDSTARTWDIRPFAPTERHIRTFDGASAGIEKNLIRAGWDSDGKRIAAGSGDGSVLVWSTDTGKMLYKLPGHKGIVNVAEFSPGKEAILLSASTDRTILLGELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNG2</accession>
    <name>A0ABR3ZNG2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Translational repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SSD1</name>
        <name evidence="4" type="ORF">Cpir12675_000475</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041505">
        <property type="entry name" value="Dis3_CSD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041093">
        <property type="entry name" value="Dis3l2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050180">
        <property type="entry name" value="RNR_Ribonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355:SF9">
        <property type="entry name" value="DIS3-LIKE EXONUCLEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355">
        <property type="entry name" value="RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17877">
        <property type="entry name" value="Dis3l2_C_term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17849">
        <property type="entry name" value="OB_Dis3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNB" evidence="3">
        <location>
            <begin position="723"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="101"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="489"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="578"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1170"/>
            <end position="1286"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="45"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="137"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="147"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="200"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="272"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="489"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="523"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="589"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1195"/>
            <end position="1214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1222"/>
            <end position="1236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1252"/>
            <end position="1286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1342" mass="147804" checksum="7D2017C15DE1C979" modified="2025-10-08" version="1">MDPNQSQRPNGVPPPTSRRLHIAHRRSPSEMTPLVSVLTSPGVDQLAIQQQIELLQQQQQQLQATQQQFVMLQQGALPMTQMGHQMGAAGAFQFPIQVPQNMGLAPPQQQQQHGNSHRRTPSAVQNMNLGGPPPAPSSGASNSIGGDNNGHTGGHSGRGGRGGHQRRHSLALADARKAAEAAQQKRTTSGFQFPAAPAGGSSTNDETMSNASSEATHQSYNSNRPARGGHGRSQSMAIGSRGGAASGRTPSEGGRSGHGRTPSRNFEGNWRQNQGQPQNNSSSNNNSNNNNQDSSAQQQQPQQAGNPQGAYQPGHRSRASVNQSISSIGSFQYPPQPMMAMGNQMLLPGMNMGGMGLNAVQLGQLQALQAQAQVQGQMVNPLMGLQASQHAPMMQQGQQQNQGNSVQRKTLFTPYLAQATLPVLTSNGQLVAGILRVNKKNRSDAYVTTQDGLLDADIFICGSKDRNRALEGDLVAVELLDVDEVWSQKREKEEKKKRKDHTESRNGNRDDGPSEGGIRRRGSLRERPTQKKNDDVEVEGQSLLLVEEEEITDEQKPLYAGHVVAVIDRTSGQMFSGTLGLLRPSSQATKDKQEAERAARDGGNSRPHAIERPKIVWFKPTDKRVPLIAIPTEQAPQDFVENHQAYADRIFVASIKRWPITSLHPFGTLVEQLGKMGDVKVETDALLRDNNFASDEFSDAVIRSVGLTNWSLEAEPAEEIALRRDFRDEKIFTVDFGGTMELGNAIHVKTRDDGKLEIGFHVPDVTHFVKPGSLADREARKRGTAVHLLNRACPLLPHKLWADVCALKPNEDRLSFSVVFTVNPVTGVIEENETWAGKAIMKSTSSIDLNVLDGILAGKDEYSGPIPPWDIRTLNAVVEKFKEKRLGGGSDPIAPLRLLSQLDDENMPVRTNLFEVSGATELLEELTHTVNIWVAQKILGIHPEKALLRRHMPPSPRRLQTFVDRMTALGFDIDASSSGKLQNSLFKVDDDDVRKGMETLLFKTMQRARYFVAGKTSQELWPHYALNVPVYTHFTRPTHRFADIIVHRQLYAALNPEEGKAPVYNEDIDALSKTVDLYNVKEESAQNAQEQSVHIESCRAMDKERLAIDGDMVVEGIVVCVYESAFDVLIPQWGFEKRVHCDQLPLKKAEFRKDKRVLELYWEKGVPSSAYVPEDERPKNNMSQRVSNATAAARQAEEAERVKKEREEATRKQTETGTMSTDDVDALFDDEEDDNNSELADSMAGVSLTAGRPTQSVPGSPSRQTGNSANLHRTSSDSKVASGEGSQQSLKDKYLTFFKLREEDGEFIQDVTEMTRIPVILKTDLSKSPPCLTIRSLNPYAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNW1</accession>
    <name>A0ABR3ZNW1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000263</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19077">
        <property type="entry name" value="AKR_AKR8A1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050791">
        <property type="entry name" value="Aldo-Keto_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625">
        <property type="entry name" value="AFLATOXIN B1 ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625:SF78">
        <property type="entry name" value="PYRIDOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="12"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="329" mass="35125" checksum="C380DF4E1CFC9D2E" modified="2025-10-08" version="1">MPSITGKEVGRVGYGLMGLSWRANPCPLPQAFDAMNAALANGATFWNGGEFYGTPAYNSMTVLSAFFVTHPDAATKVVLSMKGGVDTKMLTPDGSPEGVRRSLDNILAGLGRRKFLDIFECARRDPTVPLELTLGTIQKEYVDTGKLGGISLSEVSADTIHAAAKIVNIVAVEVELSLWALEPLTNGVAAACAQYGIPLVAYSPLGRGMLAGTFRKWEDIPADSSLHHFPRFSKEAFPLNVKLCDLLAEFAAKKGCTSAQLALGWVLAQSKRADMPEIIVIPGATTAERVKENCAPVELDEAEVGQIDKILAEFEVVGGRYPEGAPINT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP12</accession>
    <name>A0ABR3ZP12_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding RNA annealing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">YRA1</name>
        <name evidence="5" type="ORF">Cpir12675_000050</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051229">
        <property type="entry name" value="ALYREF_mRNA_export"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19965">
        <property type="entry name" value="RNA AND EXPORT FACTOR BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19965:SF35">
        <property type="entry name" value="RNA ANNEALING PROTEIN YRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="76"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="175"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="189"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="204"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="248"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1902150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="275" mass="29227" checksum="720D895F0540D172" modified="2025-10-08" version="1">MSALLDKSLDEIVSSNKKNNTNKNSRRGARRSTGARPAAVAPAGGVQKNSKPARQPAGKNQAKPTQAKPAPVNSDSKVIVSNLNMQPKDVSEQQIKEYFAQTVGPIKRVEISYSPNSQSRGIANVTFSKSDGASKAFKNLNGLLVDGRAIKIEIVVGAAQASKVIPPVKSLAERATLPKNNKTQPKSAAADKNKKQEKPKVNDKNTTSANANTGKGRSQRRRSRNPNVRPKKTEAELDSEMADYYNNAPAAGAEAAPAAAPVATANDTSMDDNIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPJ8</accession>
    <name>A0ABR3ZPJ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoenolpyruvate carboxykinase (ATP)</fullName>
            <ecNumber evidence="3">4.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PCK1</name>
        <name evidence="11" type="ORF">Cpir12675_000126</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>oxaloacetate + ATP = phosphoenolpyruvate + ADP + CO2</text>
            <dbReference type="Rhea" id="RHEA:18617"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.49" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004612">
        <property type="term" value="F:phosphoenolpyruvate carboxykinase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00484">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.449.10">
        <property type="entry name" value="Phosphoenolpyruvate Carboxykinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.8.10">
        <property type="entry name" value="Phosphoenolpyruvate Carboxykinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00453">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001272">
        <property type="entry name" value="PEP_carboxykinase_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
        <property type="entry name" value="PEP_carboxykinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015994">
        <property type="entry name" value="PEPCK_ATP_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00224">
        <property type="entry name" value="pckA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006820">
        <property type="entry name" value="PRK09344.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006821">
        <property type="entry name" value="PRK09344.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031:SF0">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYKINASE ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01293">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006294">
        <property type="entry name" value="PEP_crbxkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68923">
        <property type="entry name" value="PEP carboxykinase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53795">
        <property type="entry name" value="PEP carboxykinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00532">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="9 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1902021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="573" mass="63541" checksum="5C7AD60D3AC78546" modified="2025-10-08" version="1">MFYRKYPNPSFANPRLQVIASNVNKTGLHPAGVEPHPVHTEIEEELHEKAHIDYNRVAIVANASVASLYEDALVYETGTAIISSGALTAYSGAKTGRSPLDKRIVKEPSSENDIWWGPVNKAMSPETWKINRERAVDYLNTRSRIYVVDGYAGWDEKYRIRVRVVCARAYHALFMRNMLIRPPLEELEHFHPDYTIYNAGSFPANRYTEGMTSGTSVAINFADKEMVILGTEYAGEMKKGVFTVLFYEMPIKHNVLTLHSSANEGKKGDVTLFFGLSGTGKTTLSADPNRALIGDDEHCWSDNGVFNIEGGCYAKCIGLSAEKEPDIYGAIRYGSVLENVVFDPVTRIVDYDDSTLTENTRCAYPIEYISNAKIPCLSESHPSNIILLTCDARGVLPPISKLDRSQTMFHFISGYTSKMAGTEDGVTEPQATFSSCFAQPFLALHPMRYASMLADKIETHKANAWLLNTGWCGAGYTQGGKRCPLKYTRAILDAIHSGELANVEYETYEIFNLKVPKSCPGVPAEILNPKTAWTAGVESFETEVVKLATLFNENFKNYASEATEDVIKAGPTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPU8</accession>
    <name>A0ABR3ZPU8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein byr4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000077</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034586">
        <property type="entry name" value="Bfa1/Byr4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35140">
        <property type="entry name" value="MITOTIC CHECK POINT PROTEIN BFA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35140:SF1">
        <property type="entry name" value="MITOTIC CHECK POINT PROTEIN BFA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="422"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="560"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="651"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="737"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="801"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="931"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="322"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="505"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="570"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="751"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="816"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="931"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="954"/>
            <end position="964"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1053" mass="115271" checksum="5AB56D0B35FDCF14" modified="2025-10-08" version="1">MESLRLKQREPVVADADIENWDDDDFLLDDDISFHTTQSGRQSAGPAMPRSPSSTSNRRDSHSSHISFRSERESLNGEERHIFLPEDERSTLDAIKAAANLGIPLPQNIPPSALMGGSINRLGGRKGKKVSQDGWEVDLEFPESSQALSLKQQDSSKFPETLRQVSGSSLNSMVSDANSTPLKMPPDLDTSRSPRRSPVPSTRAEPAPINLDRFRDDDDDGFFGGDTIKVTKRQQRKPLSLITPATSFQNISSLAPAAAPPPTTADDDFEADLQLPSDCKLSLRKGRDIPGLAPHNDDLDWGDGSGSLGTRYGGTKREQRSARSSSASALSPSVASSMTVESEDDTFDGLVLPPGLLNLDDRLKGLGDRRKSNSPDPKLEEPTPYPWDSVQTPSTDHEDLLDGLEFGDGAIDARKITAHKNIKRKTSRDKIPPRIKTTASITFSNSKNLGHQQPQSQSRLPRLSHGHGGSHLSLEPVSESGGPIQQRANRLPASRVGHSAQSSVSSLATPTTPMSSTSSISSNTPRRRELINKNSNSNLREAYTTNAQLLRLKRSLPVMRGPQSAKPAGLNSSFNRPSSRSDLVTPNSSRPSSLIRPKTPAVAEISSSTGLRKPAPFIPPGVSSHSQSQNVAPKGPRVIRRHTSEVYLDSRPTSRNISRTGTRSPSPRRYRAHEKATLDSSWRQFNKPKTRHFGDGHELDAFDDLPTSATIEAKFVKAPVTSGPKAALRGKLYGNIQPEQRTTTPSPAPFTPTSSTSGSYTPRFARDTASSRIAREASLAQRAPSHGAPTMQYPTPRVAQLSNRSNFSPGLPSPVRSRKTSKKTQQKPHLITNMGNSREPKNQDGMCYNPDTYRWEGNDTALAAFEPPPAAPSPLAVTIPQMVVRDKETSTPRPALITNISATKGIQVVGGMVFDPQNMCWLKISQRQNQRGARSRHSNSNLHSAAGSQSDALDSIDGDQDSDEDPFKDIPDLMDNSADSGELTPGGGRVSDVKDEWMVGEEFDVGPEFVRRQREEEERWRKKCERWLAASSGRRDKESWRWTLRDLVVGDYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRU4</accession>
    <name>A0ABR3ZRU4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase</fullName>
            <ecNumber evidence="5">2.7.8.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">GlcNAc-1-P transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">N-acetylglucosamine-1-phosphate transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="primary">ALG7</name>
        <name evidence="20" type="ORF">Cpir12675_000109</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis, transfering GlcNAc-1-P from cytosolic UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol embedded in the cytoplasmic leaflet of the endoplasmic reticulum membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a di-trans,poly-cis-dolichyl phosphate + UDP-N-acetyl-alpha-D-glucosamine = an N-acetyl-alpha-D-glucosaminyl-diphospho-di-trans,poly-cis-dolichol + UMP</text>
            <dbReference type="Rhea" id="RHEA:13289"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19507"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58427"/>
            <dbReference type="EC" id="2.7.8.15"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="18">
            <dbReference type="Rhea" id="RHEA:13290"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.15" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003975">
        <property type="term" value="F:UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06855">
        <property type="entry name" value="GT_GPT_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033895">
        <property type="entry name" value="GPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10571">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10571:SF0">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00029567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00033238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00045078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAL1902209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="478" mass="52665" checksum="5CF9401FE7D44EEE" modified="2025-10-08" version="1">MESSVAPQVVSTSHSASEKLSLISISFASIAVLTHALSQEASEPLLASLALSGLAFVLCYAMIRWLGPTFMKAGFRGRDLCKSQQPEIPECMGAICAVVYILVVIAFIPFPFFKDIVAATSGGGNKDVVFTMSGSGPEHVQQGRLLHKFPHNKLASYLSAIISLQCIALLGVGDDLFDIRWRYKWWIPGLASIPILTVYFVDFGVTSIIIPTPLQPYLGELFDLGALYYVYMACVAMFCPQSINMLAGINGIEVSQCIVIALLLALNDSLYLLTSYPHPAVESHLFSLYLLLPWLGVSFALLCHNWFPARVFVGDTYCYFSGMVFAVVGILGHFSKTLGLLLVPQLFNFLFSTPQIFGLIPCPRHRLPCFNPKTGLLEPSVTPWTPGKQPIMPMAYVLRLLGTLHCVSVTEDKDGNFTETSNLTLLNLWLVLRGPLREDRLAMEITMLQLVVGLCGLFVRHRLALLVFQADNWSMLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YBI0</accession>
    <name>A0ABR3YBI0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Overproduction-induced pheromone-resistant</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">OPY2</name>
        <name evidence="3" type="ORF">Cpir12675_006981</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000481">
        <property type="protein sequence ID" value="KAL1885350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="412"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1885350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="448" mass="47543" checksum="C69641A799E05B6E" modified="2025-10-08" version="1">MSTLNDGEIVIETTSDVVFREALKARELYPRNDSESGCAVCQSGVTLRCEDSCYTTPGYQCVQVVSVSNCRECPMTKCQPTTGNSSASSSASSSSDGGHNGPNVGVIAGATIGGVILISTVAFMVWFFFIKKKRAEQRTSASYKEMSSEKSPAEQTTARNNRSSMHTVHSIASTVLTRASNIIQIAYIPGVTNRANPTSPTVLVPPVPPIPIQVTGTVNNTPRNFEDQHFFMPGDLRASTYSDMSGFSDRTSFARQSYAMRSSVASTVYGKNAIIVAAPQTGMRVKPAMVSVRPSHNGPGGAVPPVPTVDVDKYARPKSRAESTFSVGSTFVNSASAATVTPVKGQAIRVVSGKKNSSPLTTFEVPDTASTDSASTIGNNIPQTSPFLDPEEKPSVSARMSAVMEEETACASPMATIMESKSEEGSNKRNNMVKRGSSPFSDAFATKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YCL8</accession>
    <name>A0ABR3YCL8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 6">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="1 6">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_006883</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="1 6"/>
    <dbReference type="EMBL" id="JAWDJO010000403">
        <property type="protein sequence ID" value="KAL1886058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00275">
        <property type="entry name" value="C2_PLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08598">
        <property type="entry name" value="PI-PLC1c_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF36">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00387">
        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="PI-PLC Y-box" evidence="9">
        <location>
            <begin position="765"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="885"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="678"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1068"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="19"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="101"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="154"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="170"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="191"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="678"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1076"/>
            <end position="1087"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1886058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1096" mass="122873" checksum="8B8044ACC7434AA3" modified="2025-10-08" version="1">MLPDSIPPSLPHLGLVLVPSSASSSRPSTQADSTFASSFTTNTSCDCSPSTSPETKPAVCTEEKDVPSILLLSEAPHLNGHSPVSSPKPSPPSMASLTPVASTTSSAASSSSSAARIQAPPPYSSYQTCPPYSSGVSTANTSAWNQPPPEQNKLMRRFSSRTKTFRHRNSSVPASSRETSLGPALARNASGRASSPHLNRSVTDKDSSYPSDTEDSISDPEAIYENSGEPSKFSSVYPRHIVAGVSAFKVSKKRRKQVSFSADPQSGTIIYVGDDGLKRRVIPIDNINQVRYGSDTDQYRTELGATPADADVWLTLICSMEKSRTKIIHMVLQDAKVLKQWALTLASIMRHREQDMVLLMSFNERAVADIWIKEAASLGVTDKKELDAFALPFDNIEKLCRVLHIHLPRRQLFVYFELCDTEKAASITYHQFRELLDLIRTQNPVSYIYREVIKDQEKQKLGMTRPEFFDFLRNCQRERVDGPFEKYWNGVFKTYATTRQNSLRFTEISMYNFLRSKHNVTLKKSEPTKMDQPMNRYFISSSHNTYLLGRQIAGSSSVEGYISALIGGCRCVEIDCWDGPNGTPQVLHGRTLTSAVSFESCITSINKWAFYASPYSLWISLEVHTNPAQQARMVQIMKDVFGTLLVTEPLDPASHTLPSPEELMGRIIIKVKKPVVKDDHRQGIDNKTRRRGNSLTSSSPSHPHGEITMTPSHSMPPSPVLQPVGRSKTMPMSGRGLDTGSYYNLSHESDSSSETSTENKTVKVLGDLGVYCTGVKFRGFESPEAKAFNHIFSFKEDSFEKCSRTKDLKRAMETHNRNYLMRVYPSQFRVTSNNFDPIVYWRRGVQMAALNWQTFDLGMQLNRAMFSGGNDGTGYVLKPPSLLLQRETASLTKPNQHERKEISITLNVISVQQLICPPGVRVMNPYVEIEVFHASDPRYKTNADYLVKEDMVATQKHRTRIISDNGYDPRFQTPFHIELTTRHEELVFIRFSVKLSPDTNSYPTKETAPIAVYMVKMINLNNGYRLLPLWDRKGAQFLFSNIICHIRLNYIRPITVISESPQIESRSSLRKVFGRSGNNSTATSPRSTTEKETIAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YD45</accession>
    <name>A0ABR3YD45_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histone chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">NAP1</name>
        <name evidence="4" type="ORF">Cpir12675_006910</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the nucleosome assembly protein (NAP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000419">
        <property type="protein sequence ID" value="KAL1886034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.90">
        <property type="entry name" value="Nucleosome assembly protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037231">
        <property type="entry name" value="NAP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002164">
        <property type="entry name" value="NAP_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11875">
        <property type="entry name" value="TESTIS-SPECIFIC Y-ENCODED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00956">
        <property type="entry name" value="NAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143113">
        <property type="entry name" value="NAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="76"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="294"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="97"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="250"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="294"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="331"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1886034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="345" mass="39685" checksum="46418FC930661752" modified="2025-10-08" version="1">MNMIQGRLGSLVGRPSGYIESLPASVRRRVAGLKGIQQEHSKLEAQFQEEVLELEKKYFAKFSPLYQKRATIVNGAQEPTDEEVKAGEEEDEDNEMADVKDDDKKSETTGEDIKGIPEFWLSAMKNNISLADMITERDEAALKHLIDVRMEYLEKPGFRLIFEFAENEFFTNKIITKTYYYQAESGYGGDFIYDYAEGDKIDWKADKDLTVRVESKKQRNKNTNQTRIVKRTVPTDSFFNFFTPPVPPTGEEDDEEQDEEIEARLELDYQLGEDVKEKLIPRAIDWFTGEALAYEEMDEDDLEGEFEDEDDDEDDLSEDHDDEDDSDDDDGTGKPKQEAAECKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFB7</accession>
    <name>A0ABR3YFB7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006774</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000373">
        <property type="protein sequence ID" value="KAL1886990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="2">
        <location>
            <begin position="213"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1886990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="569" mass="60637" checksum="5168B48E07C9392F" modified="2025-10-08" version="1">MAWPNVSMQNQCIVAEGALQSPKPSPSYSPPPKIDAFVSDSVSPTSAYAMPSPDSFSGLLAGNSDSDDLAIQEFGPKFSGALGNTSDGVSAGGEQGLIPFPLLVPAAVNGPAARETQLLLPSAASYSNRASALTSAQASSASGSVVMSRSSTRPSSQGSYKGYNDSSDSLLPCAQVSPAPDAAESQMKVSASAAPPHASCDAFVPTTATQKDEKRPLTPRQRNRHAAARSRHKKKMERMMREEEYARTTELNSRLHQEVRDLCAEVERLHAVVQGHVHCNDPEIDQYLYGKAAAQAQTSATGLNHRTIAISGQGDFQLGSLRREHVSDAQTWDMTPMVPPAQPLPQNLTAETYQTSQFAHVQNDYLQHVRKQVPPAQPSLPYAKSLSQQDVHQGVPPNEQHLCRLGTPPHQMASGLPPPCPKNLVGSNRASRSRSLTVAAQALAQAVAQAPELVLSLAAERCPSQNIAPLSPLGTNTSSQSLPISTPIAQVPLMSTGSVDMDFHFPNALTSRDPQVYIPGFPEGLNAQAVARFGDGGEPVLGANSDRSGQYQPYYDEMMNMNVCELMGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGG8</accession>
    <name>A0ABR3YGG8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006551</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000320">
        <property type="protein sequence ID" value="KAL1887423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="167" mass="18387" checksum="E1BBB4F32EAA0408" modified="2025-10-08" version="1">MSAMNFSSRPLATVPESGAHLEHTTPLNHSRSRATDMSTDSTLHEKGMDVDEMQALPSPIYDHPVNSFETDVEAMIPNSQTTRGSRKTMNLSTNSDCQVWPGHDHWKRRARAAKKERTCTCLANLSKRNRIIVKVAIGLLIISVAIAVGFGVSKPLGAPIWGDKHDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH80</accession>
    <name>A0ABR3YH80_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006598</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000331">
        <property type="protein sequence ID" value="KAL1887310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="446"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="127"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="472"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="595" mass="61836" checksum="4129E50847095A95" modified="2025-10-08" version="1">MADPQLHPRHQPKQQQQQQQPPQPQQRSGSSRRRPFSTWVRKLANFNKNLSLSSSPSPASANSNNNSSASCNDPQQTDAINASSSLGSARYRLSTSHQDRLRQRNRSDSESAAPTTTNQSAKHARNSSITAAAAPTSTSKSRPKLTYHMKMKKPSKNNNPYPQSARLVELMRHRPRNTGPHSSLPSFFSAAPSTARSNTSLESSFIEVYSSNGGILLPAQSHGVSTISGDRNGSGSGSVDTASVNASIISSNGSLRHPPTISGSRSIAATVMTDHETARSALTATTNLTIGAATDRSSAMRGSGGNSTFSSPAPSVRSLATTLTTIQSLAISAANPAPNSHHHGMHHMNAGATSHTTITFNQPFPTAPPASALPPYLAPSTPGHPTTYATATANNLLTDNASILTLASSSKHRRRRSFDTDASVRALAPSSLWGGSRESLPLSILSANLESGPPGGGPGGSGSGSGAGSFGAMGPSVSVPPTTSHSNALSLSDRNSIYTSINPSTVTSNVTGARGDGSSLRSMRSGGLHLQNIADSVGSSGPTVSSPLASPMEDASLETQSLREATFGTKDTDEDTKKALAKGKEPIALSHIVYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHL0</accession>
    <name>A0ABR3YHL0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006577</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000327">
        <property type="protein sequence ID" value="KAL1887352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="257" mass="28878" checksum="39803714B4BD976C" modified="2025-10-08" version="1" fragment="single">MLFSKQFPGKQPEMSTEHIAAPNIIRDDGTIRYGLPADEIAVEAHPASDPGPYCANSHGQSPSSSAASIDSGAAYDHEDYYPQPRSNEEQYALDTPYEDEISWTIAQNPGPFFFELGPEDDDAWPLNMSMEQALALFKGSWPLSADDWAISLQPVFRYHVVNSPKWLIPETIVTWYDEDGRQVWMGDAILSALDMRDHGTKTYFLRKVVYDAKSPQNIIEGVFRMTSRHPGNVGYVLTHDGTNRILVAPHMRQLSVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIF9</accession>
    <name>A0ABR3YIF9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_006298</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000278">
        <property type="protein sequence ID" value="KAL1888115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1888115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="127" mass="13879" checksum="E07446119E013E99" modified="2025-10-08" version="1">MVLAEVSVLATRTRPSPAPVTAPPPPVPPTILHIRDRSVVAPKLTWCQRDITSTLPDVFYEKLSHKPRRQFLVTASAFPRIAKGHGLPTTWDWAPYVGIHMMSFEVAVFGARCQDSDGCASTAPSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIQ2</accession>
    <name>A0ABR3YIQ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein csh3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">CSH3</name>
        <name evidence="2" type="ORF">Cpir12675_006253</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000272">
        <property type="protein sequence ID" value="KAL1888204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013248">
        <property type="entry name" value="Psh3/Shr3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28228">
        <property type="entry name" value="SECRETORY COMPONENT PROTEIN SHR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28228:SF1">
        <property type="entry name" value="SECRETORY COMPONENT PROTEIN SHR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08229">
        <property type="entry name" value="SHR3_chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029187">
        <property type="entry name" value="Shr3_AAP_chap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00786">
        <property type="entry name" value="SHR3_chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="212" mass="23814" checksum="64BB1B593206A514" modified="2025-10-08" version="1">MTKWIDWSKSSASSSYRGTGSFATFMIIGPTCFFLGILFASFPYDYPLLWTSDPVPAEYYDQLAIHLKWMHSSPPLIGRILNIVVTVGFAGFFLKLFRPSEANFLFDGASLILYFIGVAVYIANIVKTLRAVSADIWSDPEYIEEARVAAETGEIYIGREDSMRVLSASNTILALVLVGVLVLQAGQWYAEHKEFDDIRKQQAEDEKAKKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJZ1</accession>
    <name>A0ABR3YJZ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein N-terminal and lysine N-methyltransferase EFM7</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Elongation factor methyltransferase 7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">EFM7</name>
        <name evidence="7" type="ORF">Cpir12675_006205</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000265">
        <property type="protein sequence ID" value="KAL1888350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008112">
        <property type="term" value="F:nicotinamide N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03223">
        <property type="entry name" value="Methyltr_EFM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025784">
        <property type="entry name" value="EFM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF10">
        <property type="entry name" value="PROTEIN N-TERMINAL AND LYSINE N-METHYLTRANSFERASE EFM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51560">
        <property type="entry name" value="SAM_MT_NNT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="79"/>
            <end position="81"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="288" mass="31746" checksum="F9D39262E6B00DA0" modified="2025-10-08" version="1">MTEPEEVGDLFQDPEDFYPPTPPPTMQTYELDSGKTINLHLVGHSPLEAHHLWNGSRVVSKLFERDPALVRNKTVFELGAGAGLPSLVCSVLGARRVVVTDFPDVDLVKNMQKNIDECDAMLAGGSGCISNTVVARGFVWGADVGPIMAAAAGTDVSEEERTDANPSAESPGHRLPSPTERFDVLILADLLFRHAEHGMMVKTIRDALKKTRSAQALVVFTSYRPWLRAKDLMFFDLCRADGFVVQQILEQKLDKPLFENDPGDVEVQKTVTGWTVTWPEEAWTADGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKR4</accession>
    <name>A0ABR3YKR4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_005998</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000240">
        <property type="protein sequence ID" value="KAL1888909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12339">
        <property type="entry name" value="RRM2_SRSF1_4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF51">
        <property type="entry name" value="SERINE-ARGININE PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="72"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="140"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="210"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="277"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="299"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1888909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="308" mass="35744" checksum="290045DAB3B5931D" modified="2025-10-08" version="1">MAGEITDIKLMNGFGFIEYKDPMDARDVVPAFHGTNFMGERLTVQFARGSRFRDNGSGSGDRSGPRPRRTPHRMQITGLSEGTSWQDLKDFARHSGLDVIYSEVDQDGPGQGFVEFETDADLRNAVEKLSSKEFRGKQVTCVADPQPDIPTTSRDFRGRSRSPIPRGARYTRQDMGPGSMSNYGPYSYYGPDPIDNFDRRGPPPPRGYSPRRDRYRDHFRDRSPPRRDYYDDRRAGYRSPHRRPPMDDYDRRPYDDSYRRDYAPPPDSYGRPPIYDRPPRDYPPRESGYHLARNAYPPRDYDRGGRYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL46</accession>
    <name>A0ABR3YL46_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_005981</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000239">
        <property type="protein sequence ID" value="KAL1888918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF149">
        <property type="entry name" value="UBID FAMILY DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="49"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="298"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1888918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="436" mass="48517" checksum="7AC66528864AD0AC" modified="2025-10-08" version="1">MALISSLMRREDDVAAGIDSSFNAKLKVEGWTLFSIALLLTILRLYATAVRAGGPKNWLLDEYLIILAFLFYIFLVGSLNVIASNGGANLFPPQQLATFTQEQIEKRILNSKIVVVSEQAMLNTIYVLKACLLVMYTRLTVGLRTQKAVRALSIYALIGWLATEISYFTMCMPFNQYWAIPPDNEQCATLEYYGVVQGVFNISSDMMMLSIPISIVVNLQVPWRKKLVLGLVLTMGIFVILAAIMCKIHNLSNVYSHNYMLWYIREASVALYVANMPMVWPILREWFPVLNRFGPSHSGRGGNGDSGIKHDTGLAGMPGSSSAGKTNAGMHGSRFGTVTTSVYHHKRRHSLHSISDTTDEMALQDMQKKKHRSMKGDNMGGAFDEERAIDLPKNGITVQQTVVIEKSSVKSMSMVDGLDFDFDGRPASKPRDHLNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLB5</accession>
    <name>A0ABR3YLB5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_006097</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000251">
        <property type="protein sequence ID" value="KAL1888667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025016">
        <property type="entry name" value="DUF3955"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23051:SF0">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23051">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35, MEMBER F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13127">
        <property type="entry name" value="DUF3955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="318"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3955" evidence="8">
        <location>
            <begin position="49"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="7">
        <location>
            <begin position="197"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="128"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1888667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="347" mass="38458" checksum="E2746C2CE5CD7529" modified="2025-10-08" version="1" fragment="single">MTDADFHRTGRLSDYDQTLRTRSPSVLSGRSEISALAEAVGLGGLGRRTLGISLLMVTVILWTCSNFMASSIFSDATYDKPFFVVYVNTSIFALYLVPSFVKFVYKHGLSGLRIEAHHIWAEYQLSKKSPSSSSTSRFLRLDNESSPNHGLLSSIDDNDGRDSLDRLPNEEDSIKGSKEQDTTRLSMLETLRLAAEFALLWFFANYFSSACLQYTSVGSATILSSTSSVWTLAFCALFRVEGFTRRKLFGVLTSLAGVILVSTVDLSGSRDEDRGSFPHKSQSQIAIGDAMAFTSAIVYGMYVTVMKGRVGNEERVNMPLFFGFVGVLNLVFLWPGFFILHWTGMET</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLJ0</accession>
    <name>A0ABR3YLJ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005867</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000225">
        <property type="protein sequence ID" value="KAL1889221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053083">
        <property type="entry name" value="TF_kinase-domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44305">
        <property type="entry name" value="SI:DKEY-192D15.2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44305:SF24">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE C03B1.5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="102"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="525"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="327"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="535"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="605" mass="68574" checksum="2B948CD245EBBE90" modified="2025-10-08" version="1">MVNIWWDNDRIESTVTHAFVCQHLLPQEIDRLGRQVGFGDGLTNDTYWDWIETKVKRIFLILVDLGVPDQIFGLIDDSWSDTDLPLDLENISRLALATAKDERLERRFYQRQFLYMVRPLKKSANTIYGDNEMVPIDHVDKKTPIVPNAVDRVTIGNDHDVVYWRQRMPLDVQGGLLSSQFQETVDNMRSIENDHIVSYWGSYVYQGVGYVLYTPASEFSLKSFFTSRPVSYKNLSKPLRKELVMNWIMCLADTICFLHSHQRAHSYIKPSSIHFTKNNKIFLSDTSNMGPNSMNKGADRSASFDREWYDYAAPEQWFKPSGPNAGPSRQPSFLSSSPESFSISTPRTECHNTAPSLHTHNNLQLSPQAADIFSFGCIILELLSFLLKKQHKFASHRAAKHKTAGRGGAVLDSSFHKNLNQVESWMTDLAKEANKKPLYKDGNHIYRGFIPLLRIVACMLATNPQDRPSAQEVQQRIYEIVTEQCNIAEPHCVHRYDFDFGFGQAHAHSDTMSVCTRQISAPGYVTRSSGRHNRTSSSGGMSTYSGSTGSASLLDKDRELIVNIDTMRSLRSRDHGSSVPNSPVIWEGLQVTPSPVEPSYRGGMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLJ5</accession>
    <name>A0ABR3YLJ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Endocytosis and vacuole integrity protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MON2</name>
        <name evidence="9" type="ORF">Cpir12675_006046</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MON2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000245">
        <property type="protein sequence ID" value="KAL1888762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032629">
        <property type="entry name" value="DCB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032691">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HUS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032817">
        <property type="entry name" value="Mon2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF333">
        <property type="entry name" value="PROTEIN MON2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16213">
        <property type="entry name" value="DCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16206">
        <property type="entry name" value="Mon2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12783">
        <property type="entry name" value="Sec7-like_HUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Mon2/Sec7/BIG1-like dimerisation and cyclophilin-binding" evidence="8">
        <location>
            <begin position="4"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="Mon2/Sec7/BIG1-like HUS" evidence="6">
        <location>
            <begin position="199"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="Mon2 C-terminal" evidence="7">
        <location>
            <begin position="1000"/>
            <end position="1222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="474"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="764"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1600"/>
            <end position="1620"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="7"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="477"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1888762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1751" mass="190907" checksum="3F902DDA6010F1C2" modified="2025-10-08" version="1">MTTQLLATELANLVQESKRKHNDLRQAAEKSLEELKSLKGVNETQATAELAQKATFVNPFIIACGTRNAKFTSIAIVCLQRLVVAKALPHSKLGPVLEALSQASSAGLDVQLKILQALPPLLTNYADDVQNELLVTALNICFVLQTSKNAIVNNTSAATLQQLIVAVFDKVVAEDKSGHDPFVGEAPAEDGPVKLRPAAMDAFRIFNDLCLMTENQRPEYLRFTALPQTFGLELIESVLTNHAPVFIAHAELAHILRQHVMPFLISALRGKPNFATSVRLTRILYTLIRRHLSLLPSESGQALDILTHMLDQDTAVWKRALCMEVFRGIFSEPALIRRIFMLYDSQEGEKDVLKTLTATFVRLSTEKPSVIGLGYCSTIPVLNPYANAASGSDQVVLEASGVAGILGSTVEGSTTGISSQWSTVRVPFIDQLDKTEAPPIPESYVYSLVLTCISSLSEGLAKFILPLTVPNRKKQAAKQEKDKESTEEAMDRSFKKTPIPVNPLEMKDHPLHEDIKACAKIIDECWPAILATCSTFLNAALDSEYYHSLVRAFQRIAHVAGLLHLHTPRDAFLTTLGKAAVPPNVFTACLNSGSTKALPAAESLSSGASSLLSNARGLLTRESAHSTGSATAERGKQPSFDSAAVSLNTRNLLCLRALLNLGIALGSTMGDSWRIILGTLQQADFVLFSSGKVSGRTPIVNKIQDATAENEASTLLSNFGSEIKAVETAASRLIESTVDFPNDPFIQVVEAICALLEFSEPEAIDTETSTSDQLRSLEPPKAPHVRKGSTSSISGKHRRVLSVSNVASVAPNQEDMFALAKLGDIATINIERLLAYDPETSGWEMLTKKLIGVLGSQNTSPSVRTRAADILVQLVLEAAKTVGQLEEGQRGPIQMNLFQALRNSLAPMKREQVADLGLGSVASNATDVDIQRILLDGLKNILEICGETLVSGWEVAFEIIDSIFVYLGDKSSIAVANGLSTRSAKLVRPSFNSLQLICSDFLASLPNTCFLLLVDTLYKFSSQDDDLNIALTTVTFFWTLSDFLSSKNQALSITSKIMGGQDVAELAKMAADSENEASDAALWMLLLLRLAAVTADDRLELRNSAIQTLLRIFDAYGDKLSSEAWAVCVQSVIFKLLTSITSELALANDDDTDEQEREDWNVTASVVLEGISGLLANYLNALKADESFERLWKELLRHFAQFLDFKALSINTAVYKALSQIIVEPADGSLSTETISVIWELWARGTPQSKDETKDNFDNQECLQAYVSTLCDLYRFLHPDLAIERVKTMLVLLRQAVCQESVTGFGTDVEFCTRLQDRVLASIKMIRTDLPGVPSEVISQVSEFACIAFEDYLTSKGHESSSRKIKKKRTFVALSKASMAILQDLILAHSTDSDIYKSGAFTTALRAFSRPITLKYQFPVLTRGVPAWKVATTAALEVLQNALNQPTMELEKASTAGIWAAIVDISDGIISADPSSVPESIDVMADQDFDISSFETLRDLIIPTLGNANISSETRDRFAQSLFTTSIMHELSEAESQALALPGTQALTELFKSRPGRTLNPQPLVRYKMSYVCLDQMFSLIAGEADHTPSIMVVPPTPNLQASFGPGSGGRKSGGTSSDNAKNAKELRIAIASSIATFVSIRCALTMRMYIDDTPLRGRMPQPLFQRKELLHILARLLELHSEKAALPPMKNMMTQTRKHLVILFPLLVQTAQVAGSSGDEPVLKVVMEAMAVMGVEMNAMPTATHTLRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM27</accession>
    <name>A0ABR3YM27_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000217">
        <property type="protein sequence ID" value="KAL1889405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35587:SF4">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35587">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="231" mass="25077" checksum="F78ADF370A42BB8D" modified="2025-10-08" version="1">MITAALPKRKSKNHQASDPTANTTADNPNKPPYREVLYDNTGSPILAPDAGDIIDGLDLPNDSPIHQHLQGTVGPRPNSTWTCSGTTAATTASAPDSVVGEGSKKRRGRRNRKKRSRKGAETQENSAIESEPDLNTSRPSCSCSSNHANYQQHTPGPLSYQANKPSVHPFYDPTSKSPHANKVKAKKNKSVQSKEAQDSEKQPVKLRLGLNLKLNLELKAEIEGDITISLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNJ3</accession>
    <name>A0ABR3YNJ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Kinetochore protein NDC80</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">NDC80</name>
        <name evidence="15" type="ORF">Cpir12675_005788</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the NDC80 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Chromosome</location>
            <location evidence="10">Centromere</location>
            <location evidence="10">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the NDC80/HEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000216">
        <property type="protein sequence ID" value="KAL1889453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.30">
        <property type="entry name" value="Ncd80 complex, Ncd80 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005550">
        <property type="entry name" value="Kinetochore_Ndc80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055260">
        <property type="entry name" value="Ndc80_CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057091">
        <property type="entry name" value="NDC80_loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038273">
        <property type="entry name" value="Ndc80_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10643">
        <property type="entry name" value="KINETOCHORE PROTEIN NDC80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10643:SF2">
        <property type="entry name" value="KINETOCHORE PROTEIN NDC80 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03801">
        <property type="entry name" value="Ndc80_HEC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24487">
        <property type="entry name" value="NDC80_loop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="9 10" id="KW-0137">Centromere</keyword>
    <keyword evidence="2 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 10" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="4 10" id="KW-0498">Mitosis</keyword>
    <keyword evidence="7 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinetochore protein Ndc80 CH" evidence="13">
        <location>
            <begin position="122"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="Kinetochore protein NDC80 loop region" evidence="14">
        <location>
            <begin position="454"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="332"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="398"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="457"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="594"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="73"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF24487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1889453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="734" mass="83545" checksum="BAFCFCB279A85CB9" modified="2025-10-08" version="1">MSQDSGKWSVRRPRETLAGFGLNSNLPQPSASGLKRSSMAAGMTLSNHNHGRSLSGSRQSLAMSRPNQPGMFSRTSMGPSHTDSGFSSVKRTSTFQSKPFATPSMGTALGSTPSGAMTEADRRSSIYRSRTSAPNHAPHQSFFQAAPQVAGVPRDPRPLKDRSYQARIGQELVDYMVQYNFEQEMKHVLSQNIMKSPTQKDFNYMFQWLYRRIDPSHKFQKNIDQEVPPILKQLRYPYEKSITKSQIAAVGGQNWSTFLGLLHWMMQLAQMLDGYSNHRYDEACLESGLDVSGDHVIFNFLSQAYRDWLAMDEDVADEDAERLLAPHVENMALAFKASNSQYTSELEALEAENSRLQTEIEELEKKMPDPAILDNNFKIMEEDKAKFEEYNSIAVQRTEKYEARIAILQEELDKMMLELKEAEDERRGLQRIVDDQGISMQDIDRMTAERERLQKGIEVSSVRLEEVKKKVAEKEADASRRLDELERMVDKYNTLAYQIGLIPSSAINAEGHNYELQVVVNDSDFTSTNLLMKGSASSASDRLLADATTGYQPAHILNLDLRGKVKSNFTQLRKNISDRRSSAMDAMMKDHELLDGIKEAIEDKRNEVEALEHRVRAAEEEYEKTREVTTAQKMGSDAQIEKMEKELAKMRAGLSESVQLMEQRDMNTNIEYEQLVVRANALREELHTEIDRMLNDVIKFKIHVQKNLDDYEGFVADELEKELGSEEMLEDEGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPA4</accession>
    <name>A0ABR3YPA4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000226">
        <property type="protein sequence ID" value="KAL1889219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="376" mass="38712" checksum="2EACC5B758567B4B" modified="2025-10-08" version="1">MAITGVRDRTILGPLTTTFAPPATCSNLFGDCATCLQGWRAQVCLETKQIENTDCWPPTSAGAQSATQPLQGWGFYSPGIACPAGHYSACSATAGSTSGWEVQFSMLPGETAVGCCPEGYSCTADLANGVAQTCIQYNTMGTLSTLSCDGASTITGSTVLSNYDYFTGYAPLIQINFRDVDIGKTSSATQTVSSSSLGSARASAKATGTGAATNTDSPIIIAEGATTGYRNNGLSTSAVIGIAVTVSLGVLLTALISVCLLLRRRRRQPGGAMGPQELDGSAMNVGGIGYNDSSPVSAVSSHAMGGAKMLEMSMPPSAYHMKTADAGYSNYRGAYEPSAKMVSAPAMEPVEMEGSLPPYVHNGNMAELAVEPRSTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPS1</accession>
    <name>A0ABR3YPS1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Geranylgeranyl transferase type-2 subunit beta</fullName>
            <ecNumber evidence="8">2.5.1.60</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">BET2</name>
        <name evidence="10" type="ORF">Cpir12675_005602</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21240"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11537"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57533"/>
            <dbReference type="ChEBI" id="CHEBI:86021"/>
            <dbReference type="EC" id="2.5.1.60"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the protein prenyltransferase subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.60" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000200">
        <property type="protein sequence ID" value="KAL1889934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004663">
        <property type="term" value="F:Rab geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02894">
        <property type="entry name" value="GGTase-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045089">
        <property type="entry name" value="PGGT1B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001330">
        <property type="entry name" value="Prenyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026873">
        <property type="entry name" value="Ptb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774:SF11">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00432">
        <property type="entry name" value="Prenyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 8" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Prenyltransferase alpha-alpha toroid" evidence="9">
        <location>
            <begin position="9"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1889934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="326" mass="35827" checksum="B12AF48446D2F17B" modified="2025-10-08" version="1">MASREQQALAIDAHVKYIQSLDTKKDEYDYWLTEHLRLNGVYWGLTALHLMKRPDALPRKDTINFVLSCQHENGGFGAAPGHDAHMLSTVSAVQILAMIDALDELDTSGHGKDKVARFISNLQNRESGTFAGDEWGEEDTRFLYGAFNALSLLGLLDTIDVDKAVIHIASCANFDGGYGVSPGAESHSGQVFTCLAALSIAGRLDLVDGDKLGQWLSERQLANGGLNGRPEKKEDVCYSWWVLSSLAMIGKTHWIDRDKLAAFILSCQDSENGGLSDRPGDMVDVWHTLFGITGLSLLGSPELEMVDPVYCLPKSTTDRILKRNTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR06</accession>
    <name>A0ABR3YR06_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000187">
        <property type="protein sequence ID" value="KAL1890280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09535">
        <property type="entry name" value="SAM_BOI-like_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAM" evidence="2">
        <location>
            <begin position="248"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="538"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="581"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="804"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="836"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1035"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="545"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="587"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="626"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="836"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1035"/>
            <end position="1048"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1094" mass="118318" checksum="07BFEC380F8B6A6B" modified="2025-10-08" version="1">MDFQHHGYRHSHSPPRNEILERTGVNRHDPYLSVNKDAYVSRRPESVVTEFVDVDWIEDYDDMPLDLDDEDASSEYENSARNSLDSGSKSMTTVSSYDEASTPRSSASHETFAAVHNGHMTDTEIVSFYSRPKISISAPKALEDFAAHNQPVEGPRGPHLFHLNTYSFQTEDYVLSLSPLTPLAETRLATDGLTEWGRTASWPDIELEKPSVNTFEEPIHRQQPRMQRQITRNYFTNAELDPLRLALWSPEMVAQSMLNAGVEMSVTHKFIEHDIDGSIMGTLKFQDLKELGIPSFGMRTVIWNQIKVLCSLKPTSPIPLTPIEAPVTAIPQGVFGGRHQAVAASPISAASPTLTMKQSVPSRRPSRRPRTARNANPGANDIISPLDSVSIVGIEQVIPKPHRCEKGEKCRKFRRQKNLVEQFRREHPGAIEVDSQHLLIAGDPGNPNTAPRLDLCSPITPTVASPTVDFCPSSVDKASSVAARPTSDTVPSVVASSDVLGPGATPLTQPYLQADLLINVKKRDPQDNVKQFLDFQRAQTHAPSEVPPTPPFELFPMPSPKQLQPNHLLRTLPRLSIPGKSAALPTQQQQQQQQQQQQQQPLGCQRHASIGKSGLSQVTNVEDSPAKQQQASAKDSSQPSTNSNAAFVPYSMEKASPLAQELASPTSAVADPFRFGTPFSEMDVPMTHISSGPVARSVSQSVPPEMKLNHSYSHALPVRSQSRASHRRPSFSIMPAVDEDREIPPFMKSGPKAPVPARGPMGIATPPPSGATLKAPPRFNYPWSPVERKIPFETAIPPVVKPATVPTAVTPSTTPATVTSDTTTATTVTAPAVTAPKVDASSSSVHSASSHESMTTATASSLTSVSSTSSSSSTPAPPAGSGITHQGPMKKRRTHFLRYEWQDGFFTLKGTRLAMHKDSANTQRTLEYVDIDDYAIACSSLASQSKLAAKFKVASIRRGSKPKDNVANFSFQLVPAEKQSSGHGSNNGLGNATMSSGPFGAASGSRFKKRLSNGISFSQAAPATLATASASTQATGAAASEPAPAGATNGTGKTHHFAVKNRHQQIGWMRELMLAKAIKQKGEGFEVRVNGNAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR46</accession>
    <name>A0ABR3YR46_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Type I HSP40 co-chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">YDJ1</name>
        <name evidence="9" type="ORF">Cpir12675_005240</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000171">
        <property type="protein sequence ID" value="KAL1890815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.230.10">
        <property type="entry name" value="Heat shock protein DnaJ, cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044713">
        <property type="entry name" value="DNJA1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43888">
        <property type="entry name" value="DNAJ-LIKE-2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="DnaJ/Hsp40 cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="7">
        <location>
            <begin position="6"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="8">
        <location>
            <begin position="137"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="5">
        <location>
            <begin position="137"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="383"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1890815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="417" mass="45327" checksum="15EFBDE6AB45F25E" modified="2025-10-08" version="1">MVKETKLYDTLGVSPTCTEAELKKAYKVNALKYHPDKNQSNPKAEEKFKEISAAYEILSNSQKRSAYDQFGESGLEGGGGHGTMGPDDLFAHLFGGGGSGFGGMFGGGGGGMPSRGTPKARTIHHTHMVSLEDVYRGKVSRLALQRSIICPKCTGIGGKAGSVKRCAGCEGRGMKIMMRQMGPMVQRFQAVCTDCNGEGEIVLDKDRCKQCSGKKTVVDRKVLHVHIDRGVRNGTKIEFRGEGDQAPGIEVGDVIFEIEQKPHARFTRKDDDLLYQCEIPLVTALAGGTIHIEHLDDRWLTVEILPGEAIGQGAVKMIRGQGMPSPRHHDFGNIYVSFSVKFPEKNWTQDPAAFEALRSVLPAQINMPAPPSQDVTEIVDLEDVDNAGRKGFGGNTMDEDEDEDGHSNAEHVQCAPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR58</accession>
    <name>A0ABR3YR58_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7514 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005226</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000170">
        <property type="protein sequence ID" value="KAL1890830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055936">
        <property type="entry name" value="DUF7514"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39611:SF2">
        <property type="entry name" value="HYDROXYPROLINE-RICH GLYCOPROTEIN DZ-HRGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39611">
        <property type="entry name" value="HYDROXYPROLINE-RICH GLYCOPROTEIN DZ-HRGP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24355">
        <property type="entry name" value="DUF7514"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7514" evidence="2">
        <location>
            <begin position="51"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="561"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="466"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="561"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="666"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="693"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="703"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="716"/>
            <end position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="757" mass="86131" checksum="C823F538A8A2F886" modified="2025-10-08" version="1">MAPGSAPTSSAPAPPVAEFPPTHDSASTQAPNMPIIYNEMFVKQPGEHPVATRQFCDLAIALADYISSSIGDLNNKTLTPSKMADFYRLVSTGDSWDSFWLDTNATALSQILRTIGAFHSLEPTSNPYEPPSIPALTREGFVRWLSLQILLSPEDNIAYLQYAVQNFCLRHPATGQRFPPNLPSVVFRRTPDPEVTNWHNRCGDKLKKRLEHQQKREKREKHERREKRQKEHESETKPAPASDFKQADSSKLHPTAAASSSAKHAEPVAKTSKSKSFKSPEAEAAGAKRSFLRSHIRSTSASLLPEKTTISHDFGDGHRHRGQTRMRSFEHTSKYDKDRSMYYECPEIVANYYDISKTPLPKYQGSPTTNPMHNYPRDGGVDGRRHTPTFQPHSYSYQAHTWTPPQILRHSSVTTPIHQTSFTPSPHGSMGSNGSFPPDMENRHINTPETLSPRRRSHRHRAEHGQTASGAIPMSSTPRIRVSMDKAASRAVPLIVSSSPRNHYFGRTAKQLDDENDEYIYSSSANVSPTTYPKSAKSKHRNGAHMLESFWNAFTSAAAEKEASRESSREAEKERVRSREREYEREHRSDRDRDRDRDRNRDRDRARTRERGRDRDHDEWRSRDRDRNRDRLGADVKSGVRPSKTRTRLPPSSSAARRHDIFQFEMSEDGDIYDSNDTEDTEDSEDDDESTVKGKRYHHTTRSRRDTGTADRFERQTGSLHTPTSAGTGRGDMGQVRRSKSHVETERVRQRMTGVYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRC8</accession>
    <name>A0ABR3YRC8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Post-SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_005184</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000167">
        <property type="protein sequence ID" value="KAL1890918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053201">
        <property type="entry name" value="Flavunoidine_N-MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12350">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12350:SF19">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Post-SET" evidence="4">
        <location>
            <begin position="122"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="192"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1890918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="220" mass="23999" checksum="3AEE73C38D77BD1F" modified="2025-10-08" version="1">MSSPLKPHWDQPSHSDIQEVIISTDGFLSRSLSRVELPPFAVFAKMSWPPCTEASEPTYATVQFSKDRHLNLNSDLLYINHSCDPSVIFNTSTFEILVGPKGLKPGDELTFFYPSTEWHMAQAFDCFCQTANCRGRIAGAKDMTAEQLSGLYLNGHIHALIEERDAALAGKKLPANHPPAVSCYDTGLETEAKVNGTAPKTRNGPTSRELGGEMGGDTVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRL1</accession>
    <name>A0ABR3YRL1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000182">
        <property type="protein sequence ID" value="KAL1890490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="182" mass="19715" checksum="B930311F5DA466CE" modified="2025-10-08" version="1" fragment="single">MAREDAIGDATEARPEQNPKTPLEDVEMGAAETETGPEDDATLQTMNVNSAASPDNIAQYIDSNKAQKESVALPKSNTNNATDTDKAPTHENTKPGGPKTEKERNLATVQNHLEREMKQAMRRGEALMWLDEKIPEVCNEAVMMAKGDASVKKLAGHVSAEFRAMLLKLQGINVPQSPPPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSG9</accession>
    <name>A0ABR3YSG9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">pH-response regulator protein palC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_005230</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the palC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000171">
        <property type="protein sequence ID" value="KAL1890805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.280">
        <property type="entry name" value="alix/aip1 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004328">
        <property type="entry name" value="BRO1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038499">
        <property type="entry name" value="BRO1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037505">
        <property type="entry name" value="pH-resp_palC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40463">
        <property type="entry name" value="PH-RESPONSE REGULATOR PROTEIN PALC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40463:SF1">
        <property type="entry name" value="PH-RESPONSE REGULATOR PROTEIN PALC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01041">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51180">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRO1" evidence="4">
        <location>
            <begin position="1"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="447"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="470"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1890805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="479" mass="51752" checksum="FA07CD6CF96B8D10" modified="2025-10-08" version="1">MPFQFTLPTTSAVSLTSSINCLSHPSLSITATTYRGVVRDVLKTHKRLPASERAHHVGVVVAAITNYLPYLLALDSGLNAHRGPMPTVNVVMATIPLFSWRPSLSDSPVPGREISRVQVSGLDDEIAFVMTTLASCYTLQARSALYPLYTTTGLVPTSEVRTGAIQTATRHLLDAASACMYLAGRTDGGSPTSATPASACLDVTPATARALDALGLAEATLLAVMKDDPYPAAVAQDRHMDDREWMYKAPDIPKVRAHLFARLCLAAADHASRASALLQTAATISGSKPNSDLVRYISGLRQSSRAKACRFFGIDADLGGQAGNSIGWLNAGLQELGVDARSIMKKSNGGSSSGFGKLRREWAEKREDRRVEKEAWWGVDGGCIEETRVIQMLHEKWTKVNDTMLTQAIPTPGSLLAQMPSGREIHVVKPYVVPQLEPAVLENMRAPPDHTETFASQDNDASSEDDMIDEREGSGRAYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSL1</accession>
    <name>A0ABR3YSL1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">t-SNARE VTI1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">vti1</name>
        <name evidence="12" type="ORF">Cpir12675_005188</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VTI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000167">
        <property type="protein sequence ID" value="KAL1890922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15862">
        <property type="entry name" value="SNARE_Vti1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.400">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038407">
        <property type="entry name" value="v-SNARE_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007705">
        <property type="entry name" value="Vesicle_trsprt_v-SNARE_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230:SF26">
        <property type="entry name" value="VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230">
        <property type="entry name" value="VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05008">
        <property type="entry name" value="V-SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12352">
        <property type="entry name" value="V-SNARE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="11">
        <location>
            <begin position="130"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="43"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1890922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="228" mass="25699" checksum="29A2EC6815DC7CB1" modified="2025-10-08" version="1">MANPLDTDIGSELFGSYEAEFKLVQTDLNQKLEQIPELSGEPRKAAISQAERALEEADELMGQMRLEKQNIPATAKTKVNQRLRNYESEIDRQRRKLRTLADDRAALFGSRYTDSPGGSASDVQLEQRQQLLAGTDRLDRSTQRLKASQALAVETEALGASTLADLHRQRETIQHTHDTLLQSEGYVDRSVKTLRGMARRMATNRIITISIITILVLLIFAVIFSKFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTB7</accession>
    <name>A0ABR3YTB7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Succinate-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="6">1.2.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">UGA2</name>
        <name evidence="8" type="ORF">Cpir12675_005055</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>succinate semialdehyde + NAD(+) + H2O = succinate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13217"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57706"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>succinate semialdehyde + NADP(+) + H2O = succinate + NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13213"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57706"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Amino-acid degradation; 4-aminobutanoate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.16" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000160">
        <property type="protein sequence ID" value="KAL1891209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07103">
        <property type="entry name" value="ALDH_F5_SSADH_GabD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050740">
        <property type="entry name" value="Aldehyde_DH_Superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010102">
        <property type="entry name" value="Succ_semiAld_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01780">
        <property type="entry name" value="SSADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353:SF5">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="7">
        <location>
            <begin position="21"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1891209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="487" mass="52161" checksum="604B0085C88821BE" modified="2025-10-08" version="1">MKFELKDASLLKTKCYVNGEWVGAASGLEFDIENPSTAKIVAQCPDFDEADTTLAIKAAAAAFPTFKKTSARSRARLLRKWYDLMIENHEDLAQLITLENGKTLADSRIEVTYAANFLEWFSEEAPRIYGDTMEASNPSARMITTREPIGVCGLIAPWNFPAAMITRKAGPALAAGCTLVIKTPGEAPLTALALSELAHRAGFPAGVINFVTTLKHTPAVGKILCTHPTIKKVSFTGSTPVGKLLMGQSASTLKKLSFELGGNAPFIVFEDADLDKAVAALVGCKFRVSGQTCVCANRIFVHKDVHDVFVRKLANAIEPFVVGDGFNPASTHGPVIHGRAIAKVREHIEDAVRQGATIAAGGKALPELGPYFHQPTILTGMKAGMKVCSEETFGPLASIFQFETEDEVLALANEVDVGLAGYFFSRDASRCWRVAEALEVGMVGVNSGSVSDVAGPFGGVKESGFGREGSKYGIDEYLTTKMMMIGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUB1</accession>
    <name>A0ABR3YUB1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Subunit common to RNA polymerases I, II, and III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RPO26</name>
        <name evidence="7" type="ORF">Cpir12675_004863</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000148">
        <property type="protein sequence ID" value="KAL1891677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00192">
        <property type="entry name" value="RNApol_arch_Rpo6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020708">
        <property type="entry name" value="DNA-dir_RNA_polK_14-18kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006110">
        <property type="entry name" value="Pol_omega/Rpo6/RPB6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028363">
        <property type="entry name" value="RPB6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036161">
        <property type="entry name" value="RPB6/omega-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006111">
        <property type="entry name" value="Rpo6/Rpb6"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002208">
        <property type="entry name" value="PRK01099.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47227">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE SUBUNIT K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47227:SF5">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01192">
        <property type="entry name" value="RNA_pol_Rpb6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500154">
        <property type="entry name" value="RPB6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000778">
        <property type="entry name" value="RpoK/RPB6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01409">
        <property type="entry name" value="RNA_pol_Rpb6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63562">
        <property type="entry name" value="RPB6/omega subunit-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01111">
        <property type="entry name" value="RNA_POL_K_14KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="15"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1891677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="148" mass="16969" checksum="198398D8D1C19954" modified="2025-10-08" version="1">MSDNEDHGGYHAEEPYYDEDEIDVLEDLEDEDGERIPNADDDADNIVLSGDPAALTNRANEMSHKDKKIPDSERTTTPYMTKYERARILGTRALQISLNAPVLVDLEGESDPLQIAIKELREKKIPLIVRRYLPDGYYEDWTCEELLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUC6</accession>
    <name>A0ABR3YUC6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribosome biogenesis protein tsr1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">TSR1</name>
        <name evidence="7" type="ORF">Cpir12675_004763</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. TSR1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000142">
        <property type="protein sequence ID" value="KAL1891931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012948">
        <property type="entry name" value="AARP2CN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039761">
        <property type="entry name" value="Bms1/Tsr1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007034">
        <property type="entry name" value="BMS1_TSR1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030387">
        <property type="entry name" value="G_Bms1/Tsr1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858:SF1">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN TSR1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08142">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04950">
        <property type="entry name" value="RIBIOP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22298">
        <property type="entry name" value="Tsr1_G-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00785">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01362">
        <property type="entry name" value="DUF663"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51714">
        <property type="entry name" value="G_BMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Bms1-type G" evidence="6">
        <location>
            <begin position="82"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="393"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="393"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1891931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="813" mass="90861" checksum="E7F3F19F7BE73110" modified="2025-10-08" version="1">MNHSHRPTTKANPKSFKSRKATKGSLREAAKGRMGGSEFARRTPHQHVMSKLDRKNQARQRLQAKRKEHLQETHIFNGQNGAPRIVAVVPLCVDTDSRLAVQKLNESLDIASDFTNGPIYTPIDRFKQKLQYLAVPRNLDACLNATRVADFVVVLLSASEEVDQLGELMLRGIESQGLSTLFTAVDGLEGIEPAKQRTNVLASLKSFITHFHPEQEKIFSLDNRVDSSNLMRVLCNSTPKGIKWREERSWMLIEDIQLPEDFDGQTVVTGVVRGKGLKADRLVQIGDWGTFQVDQIVAAPRPTNRKGVDAATSPQAILDIPSADKDTIEGLAPEEIIMEDDDMQTEPTQQKGVLLDDYHYFSEEELEEYTIKKRVPKGTSKYQSAWFLEDNAVDDDSASDMEDMDMDNAEDSSDESVAAPEDGIEGRAEPAMTEGAPSEYPASEMIIEPDEEQDAADLASYRKLKRTEMEDDKEFPDEIELSPNVLARERLSRYRGLKSLRTSEWVVDEDRAHEPEDWRRLLRVSDYQGTRSRVTREALVGGVAPGTRVSVYISGAIPEHVKTLPSAALHPVTLFSLLRHEHKQTVSNVLINLSSEYPTSIKSKEELIMQCGARRFIIKPLFSQPGNTPNNVHKYARYLHPGQSAVATFTGPVTWGPVPALFFKRTADVENVAESSAVPSSSGLTLVATGTCLPPSTTRVIAKRIILTGHPYHIHKRVVTIRYMFFNKEDVEWFKALPLWTKRGRTGFIKETLGTHGYFKATFDSKINPQDAVGVSLYKRVFPRKAIPLTGSLSGAVASEKSDDDEGDDQMEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUM1</accession>
    <name>A0ABR3YUM1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cyclin-dependent kinase</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">PHO85</name>
        <name evidence="14" type="ORF">Cpir12675_004955</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000153">
        <property type="protein sequence ID" value="KAL1891478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07836">
        <property type="entry name" value="STKc_Pho85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF46">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="10"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="303"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1891478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="414" mass="46311" checksum="BEFEA4D2328EA66D" modified="2025-10-08" version="1">MDNKRHASSFAQLEKLGEGTYATVFKGRNRQTGELVALKEIHLDSEEGTPSTAIREISLMKELKHENILALHDVIHTENKLMLVFDFMDGDLKKYMDTHGDRGALKPPTIKSFMYQLLKGIDFCHQNRVLHRDLKPQNLLINNKGSLKLGDFGLARAFGIPVNTFSNEVVTLWYRAPDVLLGSRTYNTSIDIWSAGCIMAEMYTGRPLFPGTTNEDQLHKIFRIMGTPNERTWPNVTKFTEYKTTFPNHAPQDLRTFLPQIDPQGIDLLQSMLQPRPELRVSASDALRHPWFNDIIIQQQQHQQAQQAQMQHKHQQAAMHAQAQAQAQAQAQAQAQAHAHAQAQAHAHAHAQAQAQAHAHAQAQAQAHAQAQAQAQAHAQAQAQAQAHAHAQAYAQAQAQARAYSDAAHAYGYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUX0</accession>
    <name>A0ABR3YUX0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">U3 small nucleolar RNA-associated protein 15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">utp15</name>
        <name evidence="8" type="ORF">Cpir12675_004646</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000136">
        <property type="protein sequence ID" value="KAL1892178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018983">
        <property type="entry name" value="U3_snoRNA-assocProt_15_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19924:SF26">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19924">
        <property type="entry name" value="UTP15 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09384">
        <property type="entry name" value="UTP15_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="129"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="172"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="258"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 15 C-terminal" evidence="7">
        <location>
            <begin position="386"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1892178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="538" mass="59097" checksum="C7E0BA5BB9AE6E98" modified="2025-10-08" version="1">MATSVVPLQQVKLTQGPSPFTAEQRYWKSFKNQLLFSLPSNKAVTHISSPANASALLASATNDLFAVTSGTRIQLYSIRTRKLVKSISRFGDIARSGEIRRDGRILVAGEDTGRIQVFDVSSRSILRTWNHHKQPVWATKFSPSELTTLMSASDDRTVRLWDLTANDPTTTFHGHTDYVRSTTFLPGSMANLLASGSYDSTVRIWDPRTGTGAAAMTFKHTDPVETVLALPSGTTLLAAASNTISVLDLVAGRPLHLISNHQKTVTSLSLASGGRRVLSGALDGHVKVFETTGWNVVNTTKYPAPILSLEVVGAGHGADAVDRHLAVGMASGALSIRTRLTGAEAAKSKEREKEMEALLAGNIAAHDAKTNKKKRTLSLRKRLDLVGESADVVIAEERTTTKKERQWQRDLRHGLYATVLDAVLDRRSLDYKPITVLTVLVTLRHRNALQAALEGRDEHTVQPVLKWVCKHIMDPRYVNICAEVGILLLDLYAQYVDESAELWEGFRALRRKVRYEVERAQQASQTNGMAESLMMGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWH0</accession>
    <name>A0ABR3YWH0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Adenosine deaminase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_004885</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>N(6)-methyl-AMP + H2O + H(+) = IMP + methylamine</text>
            <dbReference type="Rhea" id="RHEA:16001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:59338"/>
            <dbReference type="ChEBI" id="CHEBI:144842"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:16002"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000149">
        <property type="protein sequence ID" value="KAL1891664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409">
        <property type="entry name" value="ADENOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409:SF42">
        <property type="entry name" value="ADENOSINE DEAMINASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Adenosine deaminase" evidence="9">
        <location>
            <begin position="15"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Adenosine deaminase" evidence="9">
        <location>
            <begin position="275"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="390" mass="43280" checksum="704FF934C9189168" modified="2025-10-08" version="1">MVVHIDPIMDFRALPKIELHAHLSGSISRRCLHGIWASKKAAKLTTLPDPVEAMPEGKHDYCLQTFFPLFTSYIYGLLDDLISVRISTGDVLQQFAADGVRYLELRTTPRRSAKFGRAEHVATVVDTVRNFNAGVGIAGVNVVGNMHVRLLLSLDRRDSAADARETLELAKKYSDVVVGIDLCGTPTVRKGAAIRFFDEYMREAHEAGLQLAVHFGEVRYDTTCNAKEALEKPGGGGVSAENAEEKENVDGVEGVLSQEDKEDEELRIMLGWNPKRLGHVVHVSERVKHMILQQGIGLTLEMCLSCNVHAKMVESYGGHHFLEWWKAGANLTLGTDDVGVFGSCLSQEYRLAAQYFGLSRDDVVRLARMGIDGIFGGEQEKARLRNIMWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWK9</accession>
    <name>A0ABR3YWK9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Protein transport protein bet1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">BET1</name>
        <name evidence="11" type="ORF">Cpir12675_004425</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endomembrane system</location>
            <topology evidence="8">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000124">
        <property type="protein sequence ID" value="KAL1892726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15853">
        <property type="entry name" value="SNARE_Bet1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039899">
        <property type="entry name" value="BET1_SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12791">
        <property type="entry name" value="GOLGI SNARE BET1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="10">
        <location>
            <begin position="78"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1892726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="152" mass="16453" checksum="7854B758FC0011B5" modified="2025-10-08" version="1">MASRFGASTLHQRDSRSSLFEGYNPPSANAPPPRAGGYGYGYSPSATPMNGPGLVPSPSGYRPATPNRRGQYNDATLNELESQNDGQVQGILGKVRILKDMSLAIGDEIRDSSALAEKMNDSFDSTRLRLRGTMNRMLVMAERTGVGWKAML</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWR5</accession>
    <name>A0ABR3YWR5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Extracellular serine-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004553</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000131">
        <property type="protein sequence ID" value="KAL1892439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052953">
        <property type="entry name" value="Ser-rich/MCO-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883:SF8">
        <property type="entry name" value="EXTRACELLULAR SERINE-RICH PROTEIN (AFU_ORTHOLOGUE AFUA_6G00670)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883">
        <property type="entry name" value="SERINE-RICH PROTEIN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="158"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="440" mass="46985" checksum="C2FEE0000AB75524" modified="2025-10-08" version="1" fragment="single">AGDYVKWVFAPQVHSVIRGAETQACIPYELANAGATGFYSGSQYVTDTSNPPVYQIRINDTTEPIFYYCGAANSCSHQQMVGVINPNSSDGWNFEHYYQLAKTAPYELLPGDDWPSESTSTATSSSPSETSSSSSSAPSSSFDDSPASSSSNSSSSKISAGAIAGISIGSVAVVIGAILLYLCGRRQGSGNLQGWPRSWVMAASTHRESTAIGSDLNDLKSMSPLGAHKISPAMESSYMDPQRAAGETIYYNNNNNADPYSQPHDRIWAGSQHQHASSHHRYSPIHMSSHGYPYPQNTYPMQHQMQHQHQQSISSQVSPLHQAHAMMPSELPISTVATPELPGSSRPTRPEELGACNPSNTVPVIPTITVAAAVDDSPTAGLGAARDPSAFDLGRADAEPSTARSMLPECSDSGQSSCSDANRSFSFGVGEEIEYRPLKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWT7</accession>
    <name>A0ABR3YWT7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">rRNA-processing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PWP1</name>
        <name evidence="6" type="ORF">Cpir12675_004825</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000146">
        <property type="protein sequence ID" value="KAL1891784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044285">
        <property type="entry name" value="PWP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14091">
        <property type="entry name" value="PERIODIC TRYPTOPHAN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14091:SF0">
        <property type="entry name" value="PERIODIC TRYPTOPHAN PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="272"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="408"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="43"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="503"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="54"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="78"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="519"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="541" mass="60038" checksum="37346DF6C4266BF0" modified="2025-10-08" version="1">MSMITATRWVPRGYAAQFPTKYAMEDEEMDRIGELAKLKLEDAQNDLAAAENGSGEEEEDNEEQEERGSKVSTAANSDEIDEDDKPMNYNDDDLKEYDLEHYDDEDNTGEGEAMAMFGNTKSLAYYKSNKDDPYITLKDEHANDEDDDEDREELQILKTDNLILAASVEDDLAQLEVYVYEDAADNMYVHHDIMLPAIPLCLEWLDYPVNKADVDVSQPANFVAVGTMDPDIEIWDLDAVDSTYPNAILGQGSDPTLAKEKKKKKKAKRANDEYHTDAVLSLSHNRQHRNLLASASADKTIKLWDLNTAKCAKSYSYHTDKVCSLAWHPTEATVLLSGSYDHTVVASDMRAPDAKAPRWGVESDVENVRWDPHDPNYFYVSTENGILHYHDVRNAPATPAATKPVWTLQAHDESLSSFDINPVIPGFIATGSSDKTVKLWNIQASGPSMVVSRNLDVGKVFSTAFAPDSEVAFRLAVAGSAGSLQVWDTSTNAAVRKAFAGRVPEGSAEKEDRMVGIADESDSESDDDGEDEEKDDSMDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX66</accession>
    <name>A0ABR3YX66_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004346</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000120">
        <property type="protein sequence ID" value="KAL1892936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42044:SF2">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42044">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="286" mass="32079" checksum="42D03304D67083E8" modified="2025-10-08" version="1">MVCFGYATRDVRSCYAIVKQILINPDIEKVVLISHSQGGIITSMVIDWALQELPQDLVRKIEVYTFGNAANHFNSPARSTTPDSYSSISQSFDSSSGNAPSSGSIDPPGNLHMPASRTHNDEPLENIEDRAIYYIEHYAHTTDYVSLISVLHFKTLKHPQGHIPNYIGRVFARTSEETSGHQFVQHYLDGMFPIEKTESGQYTAIEESEFMNSDLYIVEGLEVPKGSLGPINDVDPYEGKLDAPWIAESCQDARLTTYNSSEQGRVVKVKDMSRLWRYLNGRTPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXX1</accession>
    <name>A0ABR3YXX1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">glutamate synthase (NADH)</fullName>
            <ecNumber evidence="19">1.4.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="primary">GLT1</name>
        <name evidence="22" type="ORF">Cpir12675_004427</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>2 L-glutamate + NAD(+) = L-glutamine + 2-oxoglutarate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="1.4.1.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-glutamate biosynthesis via GLT pathway; L-glutamate from 2-oxoglutarate and L-glutamine (NAD(+) route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Energy metabolism; nitrogen metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Nitrogen metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the glutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.14" evidence="19"/>
    <dbReference type="EMBL" id="JAWDJO010000125">
        <property type="protein sequence ID" value="KAL1892695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000286">
        <property type="term" value="F:alanine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00982">
        <property type="entry name" value="gltB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00713">
        <property type="entry name" value="GltS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="entry name" value="Alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.60">
        <property type="entry name" value="Glutamate synthase, alpha subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028261">
        <property type="entry name" value="DPD_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002489">
        <property type="entry name" value="Glu_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036485">
        <property type="entry name" value="Glu_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006982">
        <property type="entry name" value="Glu_synth_centr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012220">
        <property type="entry name" value="Glu_synth_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006005">
        <property type="entry name" value="Glut_synth_ssu1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051394">
        <property type="entry name" value="Glutamate_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01317">
        <property type="entry name" value="GOGAT_sm_gam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008730">
        <property type="entry name" value="PRK11750.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43100">
        <property type="entry name" value="GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43100:SF1">
        <property type="entry name" value="GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14691">
        <property type="entry name" value="Fer4_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00310">
        <property type="entry name" value="GATase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04898">
        <property type="entry name" value="Glu_syn_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01493">
        <property type="entry name" value="GXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000187">
        <property type="entry name" value="GOGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69336">
        <property type="entry name" value="Alpha subunit of glutamate synthase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46548">
        <property type="entry name" value="alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="18" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0274">FAD</keyword>
    <keyword evidence="9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0288">FMN</keyword>
    <keyword evidence="17" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="13" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="15" id="KW-0408">Iron</keyword>
    <keyword evidence="16" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14 22" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="21">
        <location>
            <begin position="54"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00024383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAL1892695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="2110" mass="232981" checksum="F47F24C42A87AFEC" modified="2025-10-08" version="1">MVVIDEFDDRSIHEESLKQEYVPYEYQTANNGSWAGALPVKQGLYDPDLEKDACGVGFACNIKGKASHKIVSDARNLLCNMTHRGAVGSDARDGDGAGVMTSIPHKFFVKNFERDQGIKLPSPGQYAVGNLFFKPDEETLQESTRQLEELAETLGLRVLGWRRPPVDSTLLGPAAKSREPIIMQPFVVLTSAYGATGNAPTVPEPEKFDSRLFERQLYVLRKRASHTIGLQNWFYLCSLSSKNIVYKGQLAPVQVYQYYHDLVNADYEAHFALVHSRFSTNTFPSWDRAQPLRWAAHNGEINTLRGNKNWMRAREGIMQSKVFKEELELMYPVVEDGGSDSAAFDNVLELLTINGVMSLPEAVMLMVPEAWQGNELMDPKKAAFYEWAACQMEPWDGPALFTFADGRFCGANLDRNGLRPCRFYVMDDDRIICASEVGAIVVEPESVLQKGRLQPGRMLLVDTEAGRIIDDKELKDAVSSRHDFRAWLDKELITLNKVVDSIGLKVDLTPKLDEFTIQTDPSLLAFGYTHEQVSLLLAPMASDEKEALGSMGNDGPLACLADAPRLLYDYFRQLFAQVTNPPIDPIRESIVMSLECYVGPQGNLLEMNPKQCNRLLLPSPILSIPEFNAIKNINQQFPEWTVKTIDLTFPKTQGTAGYIKHLDYICKEATAAIENQDRIIVLSDRNISADRVAVSTLLASGMVHHHLVSNKWRSMAALIVETAEAREVHHMCVLLGYGVDGINPYLAMECILKLNREGLIKKKLSNDALIHNYKHSCDGGILKVMSKMGISTLASYKGAQIFEALGLDDTVIERCFRGTASRIKGSTFELIAEDAFRFHERGFPSRQTIEVPGLPESGEYHWRRGGESHINSPSAIANIQDAVRTKNDKSYEAYSRAEYEQIKNCTLRGMLDFKFDERTPVPIDQVEPWTEIVRRFCTGAMSYGSISMEAHSTLAVAMNRLGGKSNTGEGGEDPERSEVMENGDTMRSAIKQVASGRFGVTSAYLADSDEIQIKMAQGAKPGEGGELPGHKVSKSIARTRHSTPGVGLISPPPHHDIYSIEDLKQLIYDLKCASPRSRVSVKLVSEVGVGIVASGVAKAKADHILISGHDGGTGASRWTGIKYAGLPWELGLAETHQTLVLNDLRSRVVVQTDGQLRTGRDVALACLLGAEEWGFATTPLIAMGCIFMRKCHLNTCPVGIATQDPELRSKFKGTPEHVINFFYYVANEMRAIMAKLGFRTVNEMVGHVECLKVNEDLRTRKTKNIDLSLLLTPAHQLRPGVATFNVRKQDHKLYVRLDNKLISEAELTLDKGLPSRMECDIINTDRAMGTSLSYQISKRFGEAGLHSDTVHVNIKGSAGQSFGAFLAPGVTLELEGDANDYVGKGLSGGRLVIYPPRNAVFKAEENVLIGNTCLYGATTGTCFFRGVAAERFAVRNSGATAVVEGVGDHGCEYMTGGRVVILGSTGRNFAAGMSGGIAYILDINGDFMTKLNPEMVEASSIVDHAEIGYVRGLIEDHHHYTGSELAARILVDFNRALSRFIKVLPVDYKRVLAEEAAKAAEARRAQYTLPVHKKEAAKKASTALQDIEETITDGAAEKKRALVLDKTRGFMKYARRTEKYRAPKTRTKDWAEISNRLDSNELKYQSARCMDCGVPFCQSETGCPISNIIPKWNELVFQGQWKEALDRLLMTNNFPEFTGRVCPAPCEGSCVLGINEQPVGIKSIECAIIDRGFEKGWMVPRIPPVRTGRNIAIIGSGPAGLACADQLNRSGHSVTIYERSDRPGGLLMYGIPNMKLDKRIVKRRTDLMAAEGIVFKTGVTIGEDLTLDDLKASNDAVVIATGATVPRDLPAKGRNLEGVHFAMEFLHKNTKSLLDSELADEAYISAKDKHVVVIGGGDTGNDCIGTSVRHGAKSVINFELLPQPPNERARDNPWPQWPRIYRVDYGHSEVKQHMGKDPREYCIMSEEFVDDGEGRVRGINTVRVEWTKTANGGWDMKKTEGSREFFPADLVLLSMGFLGPEQRVLGDDIEKDARKNVKTPAGKYCTNVAGVFAAGDCRRGQSLIVWGINEGRQCAREIDLWLEGFTNLPVTGGVVKRSGEEVMKAVAAHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY04</accession>
    <name>A0ABR3YY04_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">MSH2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">msh2</name>
        <name evidence="11" type="ORF">Cpir12675_004390</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the post-replicative DNA mismatch repair system (MMR).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000122">
        <property type="protein sequence ID" value="KAL1892807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03285">
        <property type="entry name" value="ABC_MSH2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="entry name" value="MutS, connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011184">
        <property type="entry name" value="DNA_mismatch_repair_Msh2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007861">
        <property type="entry name" value="DNA_mismatch_repair_MutS_clamp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032642">
        <property type="entry name" value="Msh2_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003810">
        <property type="entry name" value="PRK05399.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF35">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05190">
        <property type="entry name" value="MutS_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005813">
        <property type="entry name" value="MSH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="10">
        <location>
            <begin position="731"/>
            <end position="747"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1892807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="920" mass="103231" checksum="588B79E41916D0DC" modified="2025-10-08" version="1">MSSRPELKVDDEHGFIRFFKSLPECDAETIRIFDGGDFYTAHGSNATFIAKTVYKSTSVIRQLGRSDDSGLPSVTLSQTVFRQFLREALFKLGKRIEIWASPNGRMSWKMVKQASPGNLQDVEDEIQGQFEAAPMLMAVKITIKADQRSVGVCFADATVRELGVSEFLDNDLYSNLESLIIQLGIKECLVQAEKGEDKDPELKKVRQIINNCGAAISERPNSEFGVKDIEQDLSRLLKDERAVSTLPQSDLKLAMGSAAALIKYIGALQDPANFGQFHLYQHDLAHYVKLDAAALKALNLMPGVRDGAKTMSVFGLLNHCKTTAGSRLLCQWLKQPLMDKVKIEKRQQLVDAFFSDTELRQTMQEEHLRSVPDISRLAKRFQKGKANLEDVVRAYQVVIRLPGFIGTLDGVMDDAHREPLEVAYTNEMRELSNGLSKLQDLVETTIDLDALDNHEFIIKAQFDEKLKAIRQKLEHTRREMDAEFYSSARDLGQERDKKIFMENHKVHGWCMRLTRQEAGCIRNNRDYQECSTQKNGVYFTTKTLQNLRREHDQFTDQYNRQQNGLAAEVIKVAASYCPVLSRLAGVLSHLDVIVSLAHCAVHAPIAYTRPIIHERGQGSTILRESRHPCLEMQDDVQFITNDIELTRDKSAFLIITGPNMGGKSTYIRQVGVIALMAQIGSFVPCSEAEVSIFDSILARVGASDSQLKGVSTFMAEMLETANILKSATADSLIIIDELGRGTSTYDGFGLAWAISEHIVKEIGCFALFATHFHELTALAENHTQVRNLHVTAHISGIGKDKDEKREVTLLYKVEEGVCDQSFGIHVAELVRFPDKVVRMAKRKADELEDFSAKHEDLGIQYSNDDVAQGSEMLKKLLLEWKKEVASGGLSQAEMVAKMKDLVMRDKQLLENPFFKAVKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY39</accession>
    <name>A0ABR3YY39_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1774-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000119">
        <property type="protein sequence ID" value="KAL1892952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013920">
        <property type="entry name" value="DUF1774_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37992:SF1">
        <property type="entry name" value="DUF1774-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37992">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08611">
        <property type="entry name" value="DUF1774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="291" mass="33000" checksum="01FB9128D03C72D5" modified="2025-10-08" version="1">MSSTVNDWNPFSRRDSYTDSAISKYRIWTSVSFLLSAISTCLYVLHPPGSAHSIWWWNHHYRTAFSLNSVIVNIYWAVMFINQATYMSGLWTDRTSSTSTNAAALGSHFIINNILNFFFVILFANGHFLTALLVQIINLFNLSALYHRHNSYARWMHWPVVSGPLAWTTFAILWTGAIVVPWGNSTVLRILGNITIWALLPIGLYFLAIFGDYTMGFSLAVLTWALAMGQFLEKLVSLQWIFAFIIMGLLFIASFMVAVPAWTGRRVAWLGSDANADNEGERRPLIPDQQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY90</accession>
    <name>A0ABR3YY90_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Carrier protein ymc1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">YMC1</name>
        <name evidence="12" type="ORF">Cpir12675_004344</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000120">
        <property type="protein sequence ID" value="KAL1892934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF12">
        <property type="entry name" value="MITOCHONDRIAL ORNITHINE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="11"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="116"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="218"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1892934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="307" mass="33166" checksum="F332A28C530A115D" modified="2025-10-08" version="1">MADLEETNSSLETAKDLFSGAVGGVAQVLIGQPFDIVKVRLQTSSQYGSALSAASSIWKTEGPLAFYKGTLTPLLGIGACVSVQFGGFHQARRWFEQRNAAAAGEGLNSTAASPALTYPQYYAAGAFAGIANSVISAPIEHVRIRLQTQPHGANRLYAGPWDCVRKLCIQGGGIGGLYRGGAVTVLREAQAYGMWFLSFEMMMNWDAKRLGIERKDIPTYKVALYGGLAGEALWASSYPLDVIKSKMQVDGFGKDQTYKTMRDCFAKTWKAEGMMGFWKGLGPTLLRAMPVSAGTFVVVEMTRRAIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYU7</accession>
    <name>A0ABR3YYU7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Xenotropic and polytropic retrovirus receptor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SYG1_1</name>
        <name evidence="9" type="ORF">Cpir12675_004301</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SYG1 (TC 2.A.94) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000118">
        <property type="protein sequence ID" value="KAL1893067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14475">
        <property type="entry name" value="SPX_SYG1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004342">
        <property type="entry name" value="EXS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783:SF103">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 53 MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783">
        <property type="entry name" value="XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03124">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="494"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="533"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="584"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="609"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="8">
        <location>
            <begin position="1"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="79"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="286"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="88"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="115"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="148"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="286"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="305"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="653" mass="74435" checksum="164C86CED11788F7" modified="2025-10-08" version="1">MKFAKELEQSLVPEWRVKYLDYRTGKKLVKGITRSLNRVNNTPATARSFQHAPWQAPAWRNSCPSPIVRSNTFTSTTAFDSTASQSQLANPSQKAGSSSARNSKDSFHGFLADAPDNSGSSSRPSSTEPVPGRPLDRHAAFRLPEPAIAEDEEEEEEEYPPIRKPQNVARSNSRSILRHASKSHDSPPKRMGLKIAIPTAPTRSATWTPATPSTNPLRRLFTNASMVSAREPGQLDGLLLAQERERAFFRFLDDELAKVEAFYKEKEEQAGKRLDLLRAQLHEMRSRRLSEMTEQRSRREKLTGEGSTVSFDDASTTAPTTANSIVSSYQPSFKWMEPLKSMVPYPRPGPNSRALVNMANSPQVGSMSEDSRRDYIRRPQSHQVPYRTAKRKLKRALQEYYRSLELLKAYALLNRMAFRKLNKKYDKVMHMRPSLRYVNEKVNNAWFVQSEVLEGYLSAVEDLYARYFEKGQHKIAAGKLRRFAKSNKDVSGTVFRNGLLIGLATVFAIQGLANGVELLSSSDPVIRTNTNYLLQIYGGCFLILLLFSLFCVNCWIWTTNKVNYQFIFELDPRHQLDWRQMSEFPSFMSLLFGFFMWLNFSHYGSSSMFLYYPIILISVSLLIICFPAPIFRPSARKWFVYSHVSGQVPNLDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZQ6</accession>
    <name>A0ABR3YZQ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ATP-binding cassette transporter yor1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">YOR1</name>
        <name evidence="12" type="ORF">Cpir12675_004150</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000111">
        <property type="protein sequence ID" value="KAL1893412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18597">
        <property type="entry name" value="ABC_6TM_YOR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18606">
        <property type="entry name" value="ABC_6TM_YOR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF464">
        <property type="entry name" value="ABC-TYPE TRANSPORTER CICA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="265"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="382"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="411"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="492"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="525"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="908"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="943"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1020"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1045"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1130"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="219"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="612"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="908"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1219"/>
            <end position="1477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="318"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="835"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1334"/>
            <end position="1362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="16"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="344"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="838"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1335"/>
            <end position="1350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1893412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1492" mass="164828" checksum="45BA664594BA1BCC" modified="2025-10-08" version="1">MENHESVPNPGPIALESQTLHNAALPRSQSSGFSTEHNASVSSDLQHRDGASDVAGNIGDVAASKTKCAGNSSNDTVNDPDIELSRSITTHKTASSAVAPAVLVPEADSQTKKSWFKNLNPLKMGAAPPVPESRSPSPESSASWLSLLMFHWMTPLMTASAQMQHCLYPFQNDMWTVNPNRAVEPMSLKMKNSLKNRIDGGSKHPLTFAIYDTYRFEFILAGVLQLTSSVMQVVSPFLLRYLIKFASDAWVAKKTGEPAPHISTGMGYVLGVTLMQVVMSMATNHFIFRGMMVGGQSRAALISLIFEKSMSLSGRARAGGMVDGAEKPESPQGKPAGRSKKPKNTSPSSPAANPNVDSDGVGWPNGRVVNLMSVDTFRIDQCFALFHALWTTPVQMIITLALLLVNLTYSALAGFALIFVMMPLLSRAIKSLFARRKAINKITDQRVSLTQEILQSVRFVKFFGWENAFINRLQGIRSIEIRHIQTLMAIRSGINAVSMSVPAFASMLAFITYTLTNHNMQAAQIFSSLALFNSLRMPLNLFPMVLGNVIDAWSSVQRIQEYLLAEEMEEDVRVDKMSKHAMELNHASFTWEQTQAQAPDTSTEEMAKNTAMKTDTHLEDHSADRQAFKLDNLNISFGRNELVAVIGSVGSGKTSLLAALAGDMRKTGGEVMIGADRAFCPQYAWVQNATLQKNILFGKPMNKAWYEEVIHACALQPDLEMLPSGDQTEIGERGITISGGQKQRLNIARAIYFDADIVLMDDPLSAVDAHVGRHIFENAIRGLLKHKCRILATHQLWVLSRCDRVVWMEGGKIQAIGTYEELLSNNDGFRTLVETTAQDEKRNEDSTSKEDSNEDGDISEQDSQAVKKKKPVAAPALMQQEERAVSSVSWSVYATYIRASGTLMNAPVLLALLCLVQGANITMGLWLSYWTSDRFHMTTGQYIGVYIGLALVQCLLAFLFSGLLAVLETRASKHMLSQAMFRVLRAPMSFFDTTPLGRITNRFSRDVDVMDNALGDAMRMYLFTVSMILGVFGLIIAYFHWFAVALAPLAALFFFSAGYYRSSAREVKRFESVLRSDVFARFSEGLSGVASIRAYGLKAQFLQELRESVDEMNAAYFLTFSNQRWLAVRLDFVGCLLVFTCGTLVVTSRFSVSPSIGGLVLSYILSIVQMIQFTVRQLAEVENGMNAVERLNHYGTSLEEEAPLHTIEVPPKWPEKGEIVFENVEMRYRADLPLVLRGLSMHVQGGERIGIIGRTGAGKSSIMSTLFRLVEISSGKITIDGLNISTLGLHELRSRMAIIPQDPTLFHGTVRSNLDPFHEHTDLELWSALHQAGLSTGSGSPESSPTSASALDFEKAEPTNNDASSGIHLDTFVEEEGLNFSLGQRQLMALARALVRNSQIIVCDEATSSVDVETDDRIQHTIATAFKGRTLLCIAHRLRTIVGYDRICVMDRGQIAQLDTPLNLWKDEDGIFRSMCERSGIRLEDIRRDSRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0B2</accession>
    <name>A0ABR3Z0B2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000097">
        <property type="protein sequence ID" value="KAL1894085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021842">
        <property type="entry name" value="DUF3435"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37535:SF2">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G09300)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37535">
        <property type="entry name" value="FLUG DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11917">
        <property type="entry name" value="DUF3435"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="490" mass="56497" checksum="2839385C737D3D9E" modified="2025-10-08" version="1">MVGNQSTISTTYKSSKLRELRIPTVLFLLLASVGTRPTSILHLRFGDIRVALERDPEGGPHKLLIRFTLAFIKTYLRVKDANTFLIPETFFDPSLLLSPHVFLMDIRPGERELWLPLKQDFDNILIFRRTVKTLTGYELSPNESISYQMMTTWIRRINELLSLEYPTIPYNLRYNAANEFDQSGEVNEAPRNLALDHASSGPFRNHYLAWEVGADTWVIIRGQKPHVGHSLNKRRPTDLTSEQAAPVNTDPHIKRLGRELRRLRLGSKKYKEARLKLRSEKMRLKRILKQKIRDEWTADQVVDDMEPQLKGNWRPDEAKDRRCRPQRPAQRRLVQALTAPSDNTSEGQYQRRRNAIDAIVAYCIVEEGQTVRHTNTSSSNPSRDVTTRGPQVESALQIATKSVFVKTESERPRRCFVCVGKALSLAPDDGGVEDFIREFYTAGDLSKHFRRRHLSNLRNNNEICCKVCETLLDNKMHFQNQAMRVHGLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z147</accession>
    <name>A0ABR3Z147_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cu/Pi carrier</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PIC2</name>
        <name evidence="12" type="ORF">Cpir12675_003698</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000092">
        <property type="protein sequence ID" value="KAL1894316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044677">
        <property type="entry name" value="SLC25A3/Pic2/Mir1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45671">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25 (MITOCHONDRIAL CARRIER PHOSPHATE CARRIER), MEMBER 3, LIKE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45671:SF10">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25 MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="85"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="182"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="283"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1894316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="381" mass="41344" checksum="AB788CA9F25562B4" modified="2025-10-08" version="1">MSNGSSPSGDRPWAVFSSVVSPASKAAPSKHTPYEARTELFGSYSIVESTKNATHKLSEEAAVKFEKASLKAQDATGHVQLYTGKYYAACTFGGLLACGATHTAVTPLDVVKTRRQVDPHVYKSNIQGWKTIYAGQGMRGIYQGWSPTLFGYCFQGAFKYGWYEYFKKTYADMAGDEAAHKHKTGLYLAASASAEFLADIALCPLEAIKVRMQASPVSPYNGTADGLRKIVASEGVAGLYKGIVPLWGRQIPYTMMKFASFETIVAAMYKRLPGSKDDYSKAQQTGVSFVGGYLAGILCAIVSHPSDVMVSKLNSNKEKSESTGAALGRIYRQIGFAGLWNGLPVRIVMIGTLTGLQWMIYDYFKIFMGLPTTGGDDEGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1G8</accession>
    <name>A0ABR3Z1G8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SRR1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003651</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000090">
        <property type="protein sequence ID" value="KAL1894474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012942">
        <property type="entry name" value="SRR1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42080">
        <property type="entry name" value="SRR1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42080:SF1">
        <property type="entry name" value="SRR1-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07985">
        <property type="entry name" value="SRR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRR1-like" evidence="2">
        <location>
            <begin position="84"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="303" mass="33834" checksum="871334D8F33CA987" modified="2025-10-08" version="1">MSAAEPAQEWTYVRRGKKSRRTVPATSQLHSERQPLEESSSLPQPATVMLDEIHKTHESLAHKWDVSACRKDLVKLLDDWKGPATIKVARAVCLGVGSFGAVEIGWLARKRAHMQVLAFLDIVKSLNQNSDPGAATIKCFFQEPAFTSEDCRFIKSLGHEVVISPAGFECVDENTFVFGIHLYAEIYSKILSRNLPAIFIGTSWDEWENVSLSGTNKKPHRIADMDAAYNKANFPQDDNYTFSSTVVYWKTMREHDGSSKSETDEKKTMCQNTDAIDGKADTNPSPSYVPRKTSEVIEATGIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z295</accession>
    <name>A0ABR3Z295_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000086">
        <property type="protein sequence ID" value="KAL1894663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019240">
        <property type="entry name" value="DUF2196"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03833">
        <property type="entry name" value="YwbE family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40069">
        <property type="entry name" value="YWBE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40069:SF1">
        <property type="entry name" value="YWBE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09962">
        <property type="entry name" value="DUF2196"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="193" mass="20086" checksum="E455180666BF20AD" modified="2025-10-08" version="1">MPSIPGINQVVRGALVNIVLKADQPTGRTVAGVIQDVLTRGNHPRGIKVRLVDGRVGRVKSLASETQARGDEPSTPAEPGDFGIAARQVVRGRDVRHGSGLDLAGDTGAPATEIGLDAYIRPAKGRGKGRGGAGQFGQSQRGYATDALQSTDRGEEAPVSGAAEKINLSVCPVCHVFEGDEQAVSHHVGTHFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3D3</accession>
    <name>A0ABR3Z3D3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">NADH:ubiquinone oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NDE1_2</name>
        <name evidence="10" type="ORF">Cpir12675_003362</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nudE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000078">
        <property type="protein sequence ID" value="KAL1895133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033494">
        <property type="entry name" value="NUDE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006964">
        <property type="entry name" value="NUDE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10921:SF1">
        <property type="entry name" value="NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10921">
        <property type="entry name" value="NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04880">
        <property type="entry name" value="NUDE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NUDE" evidence="9">
        <location>
            <begin position="127"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="207"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="356"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="571"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="22"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="295"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="307"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="318"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="394"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="449"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="488"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1895133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="595" mass="64951" checksum="0ED9AEF1F000BD65" modified="2025-10-08" version="1">MDVPSSPPPGGADSLVWYKLQYEQLEGELAEFRESSRELEAELEKDIELAEKRERALKERAETLGFQVEEWKRKYKESKAEASSSQQTLEKEITSLRDTNRKIQLRLREIEVANDDYERQARNTTSSLEDMESKYNQVIERSVMLEEEMKFSEQEREQSRIETQRLKAELNDLKIEAELLHDKVKKYESRQFAVISPDISVMSSPMFDKSVHGSPGSTASSPLISTPDSAIPPIDPPSPPMSDASGAQIHRPKLPLRTPTMATKRSRLPSLSASDSTTPKPRSKIFSTSVNGGRPPTSATPASATANTRKVSSANLKTPSTTTRTLTRTSGKAPASNSLSHIRSLTAQMQRLEARVHSARSKLPAPANTPPRGTSPREIHLPSTITVRSRKRTLTSATSSVVSDDSTTPSIPRMPEASTRPGVKHVSRFSSSGVGRLSFGPLPNRSPNTDTDTSISRPSSRTSISSGIGRPSSRTEIARPASRTSTVSSRAPYARPRSSMSGSVQGYGHSHSRSRGTVDFDIADEGEMRTPSRRGAYTTKVDFSASVGSAHGIPAHSAIPLPAVRRQSVGRRTSSGVPSTGFVPSGTLAELEETY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3N3</accession>
    <name>A0ABR3Z3N3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003484</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000083">
        <property type="protein sequence ID" value="KAL1894839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052254">
        <property type="entry name" value="CUL4-DDB1_E3_ligase_receptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44472:SF1">
        <property type="entry name" value="DDB1 AND CUL4 ASSOCIATED FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44472">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="291" mass="31208" checksum="E2A8409A5957BFFE" modified="2025-10-08" version="1">MLVVQDFSLVEAPRQYHSHDIWTTYSLKVGPRNSEIAASIGGSRGVLQLTNSGQLIELYGPHPRSCSPEEAGKYPRNVFAHDFLHESPSVTVAGGGTGNLWTLDTRVKDIVNVFSHGAGVTNLSVIGNHQVLVAGLKSRMCIYDLRYTRDSAAPASTTLQNNVSSPRGNSVAATPHTVFPGYINNARLGMGFAVCTELGVACTATDGGKVVLHSLGSGRQLKVPILDGVDGGGAPIVSMRFAELPDGTRHPSLYMGVGSSIYKFSSLGEEDVEMLTEREIELEGRRRIEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z479</accession>
    <name>A0ABR3Z479_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_003585</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DIF1/spd1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000088">
        <property type="protein sequence ID" value="KAL1894598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013900">
        <property type="entry name" value="RNR_inhibitor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28081:SF1">
        <property type="entry name" value="DAMAGE-REGULATED IMPORT FACILITATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28081">
        <property type="entry name" value="DAMAGE-REGULATED IMPORT FACILITATOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08591">
        <property type="entry name" value="RNR_inhib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="152"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="17"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1894598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="283" mass="30548" checksum="D32E08FCD11CF446" modified="2025-10-08" version="1">MSQPKTKRQFAGAARDPSQQEITSFFSTTGRVQSPSADTANTPAVSSHQARGRGSGIGPKLPESVQASLLSVGMRIRKSVPEGYKTTDSRYKPWALPQMNNQGSKADGSFAGKCADVNDEYKNGTNLCTTQPPHTGLIPYCGVNKIGNLSTQPVSSQGRKPDKSDDIPSLSCSQETIDPYDSDEDKQVQAHAQFQTRLGENAKKRCFELDDIMDGSDAASYDSFPLQAGGNDSVTDGASCFRGPAINLVYTDRVIAVARKPRQKPVIVQDFSEATFLDLDAMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4J4</accession>
    <name>A0ABR3Z4J4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">MOZ protein represents a chromatin-associated acetyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_003193</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000071">
        <property type="protein sequence ID" value="KAL1895554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024461">
        <property type="entry name" value="CCDC90-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14360:SF12">
        <property type="entry name" value="MOZ PROTEIN REPRESENTS A CHROMATIN-ASSOCIATED ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14360">
        <property type="entry name" value="PROTEIN FMP32, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07798">
        <property type="entry name" value="CCDC90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1895554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="373" mass="41323" checksum="361113B73D79D2F1" modified="2025-10-08" version="1">MLRFHASFPRHGKAVEPPQQQLLTDKSIPEENLDDEAEVETVDRASESTPTLISEILGPPPVGSSANGAAEPPIDGSRISPGAGTPIEQSFIPISSPPPAPSLKSHTNFSSNMQDPRGPTSSSSPILDDQMQLIVHPNDNIKKHSQHRHVHHFDSYSCVKKLQAGNYTEAQAITLMKAIRSQLSTRLAEAQDALLSKSDVENEIYLFRAACSELSNEVKNNRRVADEQMRRERTHLQHELDILSQSLGQEISAMNDAVKGMVDDRSMLRREEHKARDSVIQQLNYKISIMLTSDVKSDIETIRWILIRRAIIGIFFIGAITLSLLRYSSLARKQRELEVAEAERQKRALEATALPPDLMQGHVPPSTGTAAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4S9</accession>
    <name>A0ABR3Z4S9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAR-17a/AIG1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003144</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000070">
        <property type="protein sequence ID" value="KAL1895563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12242:SF1">
        <property type="entry name" value="MYND-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12242">
        <property type="entry name" value="OS02G0130600 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="301" mass="34945" checksum="EEE690C20F0A1EA3" modified="2025-10-08" version="1">MSKPKMPSILTIKTRILRAFELDTKQFDPSHRFETSWILSPWALFACRFVSFLYIFTTRIVLVVLYCIQDSCAASRDELSYFTVLTFYGLCFYFLFSSLHTLTYCLQGKPLLARWPHLLQAMHRLYYTTICIMPVIVTIVFWSIIYDGMWFPNVRDAWANVSQHAMNLVFALFEIIIPRTPAPPSTHTFWISIIMILYLILAYFTNATRHFYPYSFLDPGSDGAGSMGMVIAYIIGIWAGFFVAFFAFKYLVTLRIWLTENKWNMTGKFSKRDGMVIRNFPEDKPENVEAAAVTIARKSDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z583</accession>
    <name>A0ABR3Z583_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WD repeat-containing protein C17D11.08</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_003112</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000068">
        <property type="protein sequence ID" value="KAL1895779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045159">
        <property type="entry name" value="DCAF7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19919">
        <property type="entry name" value="WD REPEAT CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="253"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="296"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="409"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="13"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="502" mass="55067" checksum="0D147C9D5EEC3C7E" modified="2025-10-08" version="1">MATKSSNTARVYQQRSPHPQQPLLHHQAQLPSQSHEHQNRTSPTTATSAPYDSLANYQVYGSPTNTSPYLTSDSYDTYTSTQRTVMANTPLGLADIRPRADSTPSDAVYETAATQNGPNNYMAPWAMYAFDWCKWKPQGNSAGKIATGSYLEDGHNYIQILDTQIGNRGPSRISIEFNRVAEATHSYPVTRLLWEPPSSQKQSTDLLATSGDHLRLWSLPADSQAPQPSSTIGRQGAPPTKLTPLALLSNSKTPEHTAPLTSLDWNTLSPSLIITSSIDTTCTIWDIPSLTAKTQLIAHDKEVYDVRFCANSVDVFVSCGQDGSVRMFDLRSLEHSTIIYEPTIKDERAANGSRPLSPTLAQQTMSHPPPLLRLATSPHDTNLLATFAQDSNIVRILDVRQPGQALLELRGHSGSINCVEWSPTRRGILTTGGDDCQVLVWDLINSAPTYNNGQPSNIRNPVSAWECPYEIGNLSWVPHLASHDGSDWLGVSAGRGIWGVRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z596</accession>
    <name>A0ABR3Z596_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Elongation of fatty acids protein</fullName>
            <ecNumber evidence="12">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ELO2</name>
        <name evidence="14" type="ORF">Cpir12675_003084</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a very-long-chain acyl-CoA + malonyl-CoA + H(+) = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:32727"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:90725"/>
            <dbReference type="ChEBI" id="CHEBI:90736"/>
            <dbReference type="EC" id="2.3.1.199"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>an acyl-CoA + malonyl-CoA + H(+) = a 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:50252"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:50253"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the ELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="12"/>
    <dbReference type="EMBL" id="JAWDJO010000067">
        <property type="protein sequence ID" value="KAL1895806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF134">
        <property type="entry name" value="ELONGATION OF FATTY ACIDS PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10 12" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6 12" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="261"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="292"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="314"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1895806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="333" mass="38328" checksum="9B6E7689DB94FA9B" modified="2025-10-08" version="1">MDSFPVPTIDRPFGIQLWPIFDKLWELTMGYPREAFRFVPSVTPMSTLKETGIFVVIYYIVIFGGRELMRGRDAFKLKTLFLIHNFILTAVSAILLALYIEELMPTVVRHGIFYAICDHNGGWTQKLVVLYYLTYLTKYLELLDTVFLFLKKKPLTNFLAFLHCYHHGATAVLCYTQLIGSTAVSWVPISLNLGVHVVMYWYYFQSARGIRIWWKEWVTRFQIIQFIIDLGFVYFASYTYFTSTYFPSMPTAGKCAGEEFAAFSGMIILSSYLVLFISFYFATYKKDRTSTTRKSLRRMSQAPLPDPHHLVAKATTTGAKSSSGPTTRSRKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5E6</accession>
    <name>A0ABR3Z5E6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000071">
        <property type="protein sequence ID" value="KAL1895550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540">
        <property type="entry name" value="TRANSCRIPTION FACTOR (ACR-2), PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540:SF5">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="772" mass="84960" checksum="AEED69E9AC7320BE" modified="2025-10-08" version="1">MDYFVQDGELVSTKRGMQVSKTRHRGTRFVNAVMSTPAHQGSQSKTSFPAAFANASAPQFSSSVPAISGQSLSASVNTAPIGKGSFSVFSISKSPAPTRSVAPHALENALARTTSGRTNSITSPRSSVSSPSGGHAETASPSSNCTASSIVTPEQSETATVPLALISSCRDIAAQYCKPRDETVPVAKKGKAAKKKSDPTPRPARKNATAASKMQIKQYGGFSSFSVSVPLPKKQSSSVQTGRSTTNTFELDQKALSCLLGARKLDNVHGIIPISVFVNPFSYSAESLPVLPMVNSATDNTRFLYQLFEASMPETIFPMEHILTHNPIRSWEFFESVMKDMAKLHMVIVSSVFMEMHCRGLRPSQLLASVSFYLSRMCALVGDGLKEGNKAPTKPRPYVLECIGSMALISLFMNRHDDWHIHMKGLKRLLTSYDDINGKNADWYLIHKLRRSDTMGAFVTGCLPYLEYPRTYPDVSTVIPQHARDELRLSTHECLSAAGILPCVDTSMQNLVVFHKAVMLTKKGPPRSILFDPHSFVDEWFYVVYKLTRYPMSLRDHCSLTQTRAAGVTTPNGQSPSSNSYSLDADTCDLMSPVARVASVLFVYEFIQQIPASPTGHMVALSLLRDQIQMIVNHIKTYALGRAYSASPPKYPPSTPALAPLYMIRPVLIWACIIGYIYLFRFPVTGCDPSFKPNPKRAVFCECIYLLFPDPLDMPTETDSRMSELLDWTTISHSRLPTTLDAFVALMRAEYEAWLAQYMEGENVHDVVLATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5P0</accession>
    <name>A0ABR3Z5P0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cell survival pathways protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SVF1</name>
        <name evidence="6" type="ORF">Cpir12675_003241</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SVF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000073">
        <property type="protein sequence ID" value="KAL1895380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.370.10">
        <property type="entry name" value="AttH-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023374">
        <property type="entry name" value="AttH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051385">
        <property type="entry name" value="Ceramide-binding_SVF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033394">
        <property type="entry name" value="Svf1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013931">
        <property type="entry name" value="Svf1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47107:SF1">
        <property type="entry name" value="CERAMIDE-BINDING PROTEIN SVF1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47107">
        <property type="entry name" value="SVF1-LIKE PROTEIN YDR222W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08622">
        <property type="entry name" value="Svf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17187">
        <property type="entry name" value="Svf1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159245">
        <property type="entry name" value="AttH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Svf1-like N-terminal" evidence="4">
        <location>
            <begin position="57"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Svf1-like C-terminal" evidence="5">
        <location>
            <begin position="218"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1895380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="382" mass="42396" checksum="5A2DABF81B2C878B" modified="2025-10-08" version="1">MFNWAKQQLANVAGTQEPIHGAEAFHSIAEKAKEIETPYTEISREDIEWKVMDSTCVETQTFYFMTDSGLIGMCQVIYSNVGGLRTTCQFTSKIFSTDPSKPTLWCSNQLENPEFSEDSCSFYADGCAVELSDDGNSWSIKSMTDDRCLVNLTVTRETPGYQIAKDGLSTYGTDSENPWGSMRHAFWPRCKTEGTLTTADGAIDFKGKAFYVYALQGMKPHHAAARWNFISFQGETYSANVMEFITPAAYENSKVSVGAIVKDGEIITAGPITTCEHTKTNHDEETGWDVPENFKFTWEGQTKDGKPVSASIEGQFDPLDRIDVMAEVPGFVKKIVANAAGTKPYIYQYSTHKSKLPLKLKIGDQEITEQGVPFAEASFVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5W2</accession>
    <name>A0ABR3Z5W2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA(Ile)-lysidine synthetase</fullName>
            <ecNumber evidence="1">6.3.4.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_002995</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(34) in tRNA(Ile2) + L-lysine + ATP = lysidine(34) in tRNA(Ile2) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:43744"/>
            <dbReference type="Rhea" id="RHEA-COMP:10625"/>
            <dbReference type="Rhea" id="RHEA-COMP:10670"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:83665"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.19"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.19" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000064">
        <property type="protein sequence ID" value="KAL1896018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01992">
        <property type="entry name" value="TilS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01161">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012094">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012795">
        <property type="entry name" value="tRNA_Ile_lys_synt_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033">
        <property type="entry name" value="TRNA(ILE)-LYSIDINE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033:SF1">
        <property type="entry name" value="TRNA(ILE)-LYSIDINE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal" evidence="7">
        <location>
            <begin position="47"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal" evidence="7">
        <location>
            <begin position="318"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1896018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="716" mass="79578" checksum="4811B436D9F19E17" modified="2025-10-08" version="1">MAASPLPLLHKYAAPVSIAEFADVLRQLCKPRFPNLRPHSGHKIGGGGLDSMALAVLFSQFLKRYPHVYIGDAHISGINAFIINHSLRQGSLQEATDVAAQVQNIPGVHPVVASIDWTQYGHTNPKSQSVSMPESQDFSKISSAAFASNIETLARRARYQLLGKLCLKHNSDSLFFAHHRSDVYETILLRLLSGASRRGLSGIRPRGDIPECYGMFGVHRSGLIKALSNGQSYLGVDTSQLDVSSVGNELRSGIYDDIKSLRGKQAKQDNHTSTYGSWYLKTVSRAQQQGETPFGPCILPARKETTQNSASPADVVLEDGGVHIYRPLLPFDKDRLRATCIEYGIHWVEDKTNADPTVTKRNAIRYMATHYKLPRALQKDTILHLADRCTELNQQDASTANWLLSRTELKLDPQVGTLKVSFPNVAVSLRDRLQRRRQIMVNPKARNSQWLRRKLKIKRLRLPAAILVQKLIHTISPRKHFPDLVDIDPFISRLFPDLSPTQSFPPAKSFCLGGVLFTPLPGPPHAHWLVSRQPYVSLQPPPRVSFPTANIPTAHPDSPYIKTQPMSSWHPTHLWDGRYWICLRHRLPGHIVVAPLTPAHLSTLRNRLSRKLRQALDAVLRACAPGKVRFTLPALYYSEAVCGPAGTFSCNSNHGAVGGGDTDDHVKHLPGMQILALPTLGYVLPEAGGLVEWQVSYKMVDNDVKSQAISLSKNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6J1</accession>
    <name>A0ABR3Z6J1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Histone H1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_002892</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the histone H1/H5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000061">
        <property type="protein sequence ID" value="KAL1896245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00073">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005819">
        <property type="entry name" value="H1/H5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005818">
        <property type="entry name" value="Histone_H1/H5_H15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00538">
        <property type="entry name" value="Linker_histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00624">
        <property type="entry name" value="HISTONEH5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00526">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51504">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="H15" evidence="5">
        <location>
            <begin position="29"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="87"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="10"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="108"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="135"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="195"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="221"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="260"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00020833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1896245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="282" mass="28917" checksum="F9E4677DFF633121" modified="2025-10-08" version="1">MAPSKKSDAVADSVAAASAAAPAKKSGSGHATYQTMIIDAITNLKDRNGSSRQSLKKFVRANNTINVTDNMFDSLFNKALKAGVDKGVFEQPKGPSGGTKLAKKAPAPKKAAAPKKAAPKKTAAPKKAAPAVAAPKKETKAVAEKKEPKEKADKKEPKEKAAPASDKKEPKEKAAKATAAAVDKKKAAPKKAAAAKKETPAKKETAAEKKASAATTTPKKAAVEKKDKVASGRVSKVSTKKDTTVAVAASPADKKKATPKKAAATTKKVASSKKTKEAAASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7T0</accession>
    <name>A0ABR3Z7T0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002664</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000054">
        <property type="protein sequence ID" value="KAL1896716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024526">
        <property type="entry name" value="DUF3807"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40642">
        <property type="entry name" value="YALI0F31295P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40642:SF1">
        <property type="entry name" value="YALI0F31295P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12720">
        <property type="entry name" value="DUF3807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="198" mass="22233" checksum="940C0AEDC9264F4B" modified="2025-10-08" version="1">MESSSIPSAFSTPEISSTDLKRFHDDFFSPASFAAFGANFFPAKLQTGDVSAQTSNTNTQNEDECANHGDDYEDLGYYPDGNERTLTDEQVYMFRQSELKEMLKNWQKRKAIAEKNSVEAVFSVSDPRQDKHESKASIKTGDLPNADEEISDASTPSWGKKRKKTKNGASGLRKEPKPDLRKRTWDVVDTGLDSLEYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8H0</accession>
    <name>A0ABR3Z8H0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dolichol-phosphate mannosyltransferase subunit 1</fullName>
            <ecNumber evidence="4">2.4.1.83</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">DPM1</name>
        <name evidence="6" type="ORF">Cpir12675_002542</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a di-trans,poly-cis-dolichyl phosphate + GDP-alpha-D-mannose = a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + GDP</text>
            <dbReference type="Rhea" id="RHEA:21184"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the dolichol-phosphate mannose (DPM) synthase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.83" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000051">
        <property type="protein sequence ID" value="KAL1896963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004582">
        <property type="term" value="F:dolichyl-phosphate beta-D-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06442">
        <property type="entry name" value="DPM1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039528">
        <property type="entry name" value="DPM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43398">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43398:SF1">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="2 4 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="5">
        <location>
            <begin position="8"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU365083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1896963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="239" mass="26719" checksum="C9C848483765A8FA" modified="2025-10-08" version="1">MTSTDKYSIILPTYNERKNLPIITWLLNRTFTENNLDWQLIIVDDGSPDGTQVVAEQLVKAYAPHVILKTRTGKLGLGTAYVHGLQFVTGNFVIIMDADFSHHPKFIPRMVALQKTRDYDIVTGTRYAGDGGVYGWDLRRKLVSRGANLFADTVLSPGVSDLTGSFRLYKRSVLQKVIESTESKGYTFQMEMMVRAKAMGCTVAEIPISFVDRVYGESKLGGDEIVEYAKGVFSLFVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8P3</accession>
    <name>A0ABR3Z8P3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_002668</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000054">
        <property type="protein sequence ID" value="KAL1896720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028000">
        <property type="entry name" value="Pma1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14610">
        <property type="entry name" value="Psg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045636236" evidence="3">
        <location>
            <begin position="19"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="432" mass="47157" checksum="73CB4ED9562A35F7" modified="2025-10-08" version="1">MRASGVTALLLGACLASASPPKTAVAPSPTPALAARHEPHTTAVGIAPPMAVWVEVNADDQPVKTHTPSQTVIDGTTSLLDAPPYEITGTVFTEYHPDRTVYATRLPQPKSDGSGAFPLCTATAGADGSPFCWPREGDTLFVDTQYYIIWDPKLFDEKKIIYSITSTTTTTASSSTSLAARATETTPPLEQQISEILHRTVRIRGERVNRTNQDDELLFISDEMRGTKGVYTLKISSKYMDFKHPTNLSLTLVTTLDGDSKEYAGPTVTMKYRPVHGHSSTTTESREMYIVLPVICGLVVLMGIGMILYNRNIRHIGFGNIMGRKRGRSNHSRPNRRKGGYKQVSGQDPDQDGIQLMNGYGDSSSDEDGYADSSTTATAKGKAKGKRKLRNAMPSPFDDYPPHIPTNMATYMPDSGGSRSRYSTDPRQAKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8S5</accession>
    <name>A0ABR3Z8S5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MEP1</name>
        <name evidence="11" type="ORF">Cpir12675_002926</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000062">
        <property type="protein sequence ID" value="KAL1896218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029:SF4">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111352">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="197"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="285"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="392"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="10">
        <location>
            <begin position="38"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="483"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="489"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="536"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1896218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="579" mass="62245" checksum="22A8FE5242156ECB" modified="2025-10-08" version="1">MSYSHFGAPTTYNGTGENGGDPSFVNLNQWYTTGDTSFIILASCLVMFMVPGIALLYSGLARRKSALSLLWVVMMSFSVLTFQWYFWGYSLAYSSTASNSFIGNLHHFGLQHVLGAPSQGSPLVSSLLYSWFQLMFCAVTGALVVGAVCERGRAFPAMVFIFAWATVVYCPIAYWVWNANGWAFKWGVFDYAGGGPVEIGSGMSALAYSMVLGRRNAFLMGNYRPHNISLVMIGTIMLFFGWMGFNGGSAFGANLRAVISCWNTTLTAGFAGMAWVVLDFRLSHKLSMVGWCSGTISGLVAATPASGFISMWASIILGIVAGILCNFATKIKYILKIDDSLDVFAEHAVGGIIGLIFNGLFAEENVIALDGINVGISGGWVDHVWSRLYKQLAYICAVSAYSFGVSYVLARVIDLIPGLHLRVTHDGELFGTDDDQHGEYAYDYVEVRRDYLAWTPATDYPQTGELDGVYANPQLGIPQHATLAAASQAEKERQRGGPSEPEKISRLTRILGPTSPANRSPPRTKTDRPGSKGSGPESSNISTSPPGANGTAGVSAGASARAIPEPVSGSDVDAITKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9G2</accession>
    <name>A0ABR3Z9G2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Coatomer subunit beta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Beta-coat protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">SEC26</name>
        <name evidence="15" type="ORF">Cpir12675_002556</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Golgi apparatus membrane</location>
            <topology evidence="1 10">Peripheral membrane protein</topology>
            <orientation evidence="1 10">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Cytoplasmic vesicle</location>
            <location evidence="10">COPI-coated vesicle membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000051">
        <property type="protein sequence ID" value="KAL1896975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011710">
        <property type="entry name" value="Coatomer_bsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016460">
        <property type="entry name" value="COPB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029446">
        <property type="entry name" value="COPB1_appendage_platform_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10635">
        <property type="entry name" value="COATOMER SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10635:SF0">
        <property type="entry name" value="COATOMER SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07718">
        <property type="entry name" value="Coatamer_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14806">
        <property type="entry name" value="Coatomer_b_Cpla"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005727">
        <property type="entry name" value="Coatomer_beta_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="5 10" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="7 10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="12">
        <location>
            <begin position="24"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer beta subunit C-terminal" evidence="13">
        <location>
            <begin position="680"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer beta subunit appendage platform" evidence="14">
        <location>
            <begin position="821"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="494"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="500"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR005727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF14806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1896975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="959" mass="106529" checksum="4AED3FB4BE2D99D5" modified="2025-10-08" version="1">MATFLENAYSLVHQDNAADVPTLSDLRTQLEKGTDESKVETMKHILTIMLNGDSMPSLLMHIIRFVMPSKSKPLKKLLYFYYEICPKLDASGKLKQEMILVCNGIRNDLQHPNEYIRGNTLRFLCKLREAELIEPLLSSARSCLEHRHAYVRKNAVFAIASIYQHSQFLIPDAPELIANFLEAETDSTCKRNAFAALSSISHDAALQYLSAVFEGVVNAEELLQLVELEFIRKDAVQNTQNKAKYLRLIFDLLEAGASTVIYEAASSLTALTNNPVAVKAAASKFIELSIKEPDNNVKLIVLDKVDQLRRKNEGILDDLTMEILRALSSPDIDVRRKALTIAMEMVSSKNVEEVVLLLKKELAKTVDQEFEKNSEYRQLLIHSIHQCAIKFSEVAASVVDLLMDFIADFNNASAVDVINFAKEVVEKFPELRPSIVQRLTSTLGEVRAGKVYRGILWIVGEYALEEKDIRDAWKRIRASLGEIPIVASEQRLLDAQDDGEEKKEADESSREKPATSSGSRRVLADGTYATETALTSQSSVSAKLEAVKAASKPPLRQLILDGDYYLATVLASTLVKLVMRHSELSSDEARTNALRAEAMLIMISIVRVGQSHFAKQPIDEDSVDRIMTCIRSLAEFPKRKELETVFLDDTRKAFRAMVVAEESKRAAKEAVEKAKTAVQVDDVVNIRQLAKKNAGDGTDEMHKDLERATGGDAAAEDLSSKLSRVVQLTGFSDPVYAEAYVKVHQFDIVLDVLLVNQTTETLQNLSVEFATLGDLKVVERPTTQNLGPHDFHNVQCTIKVSSTDTGVIFGNVVYDGAHSTDTNVVILNDVHVDIMDYIQPATCTETQFRTMWTEFEWENKVNINSKATSLREFLSQLMACTNMNCLTPEASLKGDCQFLSANLYARSVFGEDALANLSIEQKGENGPITGFVRIRSRSQGLALSLGSLKGLNKIGSVGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA04</accession>
    <name>A0ABR3ZA04_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PRP4</name>
        <name evidence="11" type="ORF">Cpir12675_002546</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000051">
        <property type="protein sequence ID" value="KAL1896967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd14135">
        <property type="entry name" value="STKc_PRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050494">
        <property type="entry name" value="Ser_Thr_dual-spec_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044092">
        <property type="entry name" value="STKc_PRP4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058:SF103">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE PRP4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="401"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="136"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="246"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="332"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="43"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="66"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="90"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="172"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="430"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1896967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="728" mass="81713" checksum="37A838E1D4B9D10C" modified="2025-10-08" version="1">MPGSEDGDVSDRYSKGAFRKASSTLSASTTRTYVDRSYRHGNSYGNGSVSLDRNSNSPFADHAANSRYSRSPTRSNNRNGRPRDNYNNGRRFEDPRRLRNYDDLDEPNSRRNDRRDGYENRDRDWGREDRYDRHYNSSNARVTKRPRNCSRNRSLPSPNDKSRGPSLRSNGHIRDSVDHSRKTDSVSVLDKSDDSSKKDRQVAFALHGDIVMPTDEALEVPEPVQIDEEAEIERRKRRRIELLSKAQAAAASPTPESTSPSVASLATPENSQPLFQPPTSLVSELGSPSTSMFSEEASIMNKFTSPLVDDGRSAADYDPIVDKQKDELREELRHTHQEPKPLATSQDQDDDEDDMFADDFDVSAGKAKTVADTEGAGGLLEEVDKDGYYKIRIGDILAGRYQLQSTLGKGMFSGVARAIDLTTKELVAIKIIRNNDALRKGGLTEVSILQKLNEADPDNRKHIIRFGRSFEHKGHLCMVFENLSLNLREVLKKFGNNVGINLNATRAYAYQIFVALAHMRACTIIHADLKPDNILVNENRKVLKICDLGTAVDRSDAATSHDEVAPYLVSRFYRAPEIILGIPYDYAVDMWSIGCTLYELYAGKILFTGDNNNQMLKAIQEVRGRITPKMFKRGQLSGAHFDDKGNFISVETDAVLGNATVKVLPVVKPTRDLRQRLMKTATEMGEAETHDLALFVDLLEHCLALNPDRRLQPAEALRHPFFKSRLAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAD3</accession>
    <name>A0ABR3ZAD3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002768</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000057">
        <property type="protein sequence ID" value="KAL1896479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185:SF1">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="330" mass="36708" checksum="70659EA62F3266C6" modified="2025-10-08" version="1">MEGIQKSEGLKILPKPCGRVDLISGTTSLRTLPTLFKTYAKTTGLSECKIREVARATSAASIFFEPMKLGRDKIKYIDAGFGHNNPCESLIVEAEKLSQDRQMLILSIGTGLDDVVKIGETRKSIIEALKKMSTTSKAAELRLMVKYGDTGRYHRFNVENGLRDVILSDWELASEVSAHTNNYLQEHEVAIQKFISAMCNISRVLTQPTNLENGSHTTTKPEAYEDCEPVHYIPFDESLDFVRREGFLAALKEQLFAATSFQKVALVGLGGAGKPQIALNLAYWVKEAKPEYSIFWLTGANTSGFDEACKKRVKEFGVKVSNDEDPKELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBP2</accession>
    <name>A0ABR3ZBP2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AA1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002038</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000036">
        <property type="protein sequence ID" value="KAL1898090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047404616" description="AA1-like domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="158" mass="17206" checksum="C621E3FDC242FD5F" modified="2025-10-08" version="1">MVSFTTVLVAALAAFEGVAAGPIDYRQWPRFTVPQVHFEILSLRHSTSLNRKALVEATCIDRNAHIVFHDENAAEMAICDNFQNGDRCDGTIALTKGEKLSARFNIKAETPGATITITRLGWEQCVRAAREVCPTGSLTATCYGGASKGDISFRLDNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBR4</accession>
    <name>A0ABR3ZBR4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Actin-related protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ARP2</name>
        <name evidence="2" type="ORF">Cpir12675_002372</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000046">
        <property type="protein sequence ID" value="KAL1897268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10220">
        <property type="entry name" value="ASKHA_NBD_Arp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="388" mass="44052" checksum="52F3B73A6E8FB703" modified="2025-10-08" version="1">MTAPIVLDGGTGFLKVGYAAQNFPEFQYPSIVGRPILRTEEKGDDDIVIKDIMCGDEAAAARTMLQISYPMENGIVKKWDDMQHLWDYTFFEKMKVDPRGRKILLTEPPMNPLRNREQMCEVMFERYGFGGVYVAIQAVLALYAQGLSSGVVVDSGDGVTHIVPVYESVVLNHLTRRLDVAGRDVTRNLINLLTRRGYALNRTADFETVRQIKEKFCYVSYDLELDKRLSEDTTTLVQSYTLPDGRVIRVGSERFEAPECLFQPHLVDCEQPGMAEFLFNTIQSADVDVRSSLYKAIVLSGGSSMYPGLPSRLEKEIKQLWLTRVLGGNPERLSKFKVRIEDPPRRRHMVFLGGAVLANIMADKENMWVTKQEWEEQGVRVLEKLGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC99</accession>
    <name>A0ABR3ZC99_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA-binding ribosome biosynthesis protein mak21</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MAK21</name>
        <name evidence="4" type="ORF">Cpir12675_002021</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CBF/MAK21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000035">
        <property type="protein sequence ID" value="KAL1898313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005612">
        <property type="entry name" value="CCAAT-binding_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040155">
        <property type="entry name" value="CEBPZ/Mak21-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12048">
        <property type="entry name" value="CCAAT-BINDING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12048:SF0">
        <property type="entry name" value="CCAAT_ENHANCER-BINDING PROTEIN ZETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03914">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCAAT-binding factor" evidence="3">
        <location>
            <begin position="619"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="114"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="542"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="719"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="896"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="121"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="147"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="544"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="721"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="732"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="901"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="956"/>
            <end position="980"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1022" mass="114518" checksum="F752A117FD8C759B" modified="2025-10-08" version="1">MGKLHSAQSPKSRNAQHQRPNKRKGDYNDNKSPKRRREPRDEAQVETADSTRPLTKGSSTSRETLLSEIKALGGDDADLDLVMGVESESENEFGGDNVNGHLLNDLRKFAANLGIDAPADKEDEPEAADEEHEGEADEEDEQDEEQEKSKSKADLKKEQKEMEYKEKKQQKREEKERKKEEKKKAAEEKKAAEEKKIEVAKANEAATAEKKNFDSKKSKMTFEPRADWHATELAVLPEPSDDDITKYITVIQVIRDHAHNLLEADASLYSTTILSSSSHKFLSTIMASGTMSDKVSALTLAIQESPLHTVRPFDALISLASKKSRSQAIIALNAVVDLLGPGFVLPANRRLRTFRMQPALIGALQASKTTKWSPDRPLPGGLTPQHLIYWSYEEWLKEAYFRVIQLLETWVTDEVDYSRSRAIDFIYNLLKEKPEQEANLLKLLVNKLGDRDRKVASRTSHLMLQIQTSHPGMKPIIVKTVEQEVLLRPGQSIRARYYGVNTLNQTILSTKEAEVAEALLKVYFDQFSILLKSGDLGLPMGNEAAKEDDANPKEKGKRRRGPKAKPTSVQTGDSSEKLVAAILTGINRAVPFTNANSTILDDHLDTLFHVAHSSNFNTSIQALTLIQTLSSKRSLMMDRFYRTLYESLLDPRLTTSSKQAMYLNLLLRALKTDVDVRRVKAFTKRMVQITGIHQPPFVIGLLYVLLQLRKTMPDLSTLLNEPEDTLDDGEENKDAYDGRKRNPEFSNAHRTCLWEIVPLTLHYHPSVSVYAAGLLAGKDLPQKPDLESHSLIRFLDKFVYKNPKEKDGSHGQSIMQPLQVKNDFKDMWLRSKSQASSSSTVNNASFWNKKQENVSAEDVFFHEYFSQIGKAGQAAKKEVAADLEDDDNDEVFKALISGTDVLEEDEEDESDLGMEGYSDSDDDEEGGAAVGEDTELGDDGEGGWENGEGVALNLDSGDDGDDLMFDDESDDAMEDDEAEPELQSTSAKTRMSRKDFKALPMFASVDDYATLMENEEDEDLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCQ5</accession>
    <name>A0ABR3ZCQ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycerol-3-phosphate dehydrogenase [NAD(+)]</fullName>
            <ecNumber evidence="6">1.1.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GPD1</name>
        <name evidence="10" type="ORF">Cpir12675_002170</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>sn-glycerol 3-phosphate + NAD(+) = dihydroxyacetone phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.8" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000039">
        <property type="protein sequence ID" value="KAL1897825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141152">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006168">
        <property type="entry name" value="G3P_DH_NAD-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006109">
        <property type="entry name" value="G3P_DH_NAD-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011128">
        <property type="entry name" value="G3P_DH_NAD-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11728">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11728:SF8">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(+)]-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07479">
        <property type="entry name" value="NAD_Gly3P_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01210">
        <property type="entry name" value="NAD_Gly3P_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000114">
        <property type="entry name" value="Glycerol-3-P_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00077">
        <property type="entry name" value="GPDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00957">
        <property type="entry name" value="NAD_G3PDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0520">NAD</keyword>
    <keyword evidence="2 5 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal" evidence="8">
        <location>
            <begin position="12"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal" evidence="9">
        <location>
            <begin position="257"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="192"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1897825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="409" mass="44278" checksum="F61B2D789FF88E27" modified="2025-10-08" version="1">MTTASLVQRKHKVTVVGSGNWGCTIAKIVAENCAEQPDLFEKEVQMWVYEENVSIPSTSPYYNKEVGETPQKLTSIINTHHENVKYLPGIKLPANLIANPSVQDAVKDSTILIFNLPHQFIDKACRDLTGHILPFARGISCIKGVNVTDDGIHLFSESIGKGLNIYCGALSGANLASEIAQEKWSETTIAYAPPPLDSLSSAESSESEDDDLSHRDASGKKSTVTLTPIPAEYAPIDQTTFKKLFHRSYFHVRTVSDVAGVSLSGALKNVVALAAGFVEGRGWGDNAKAAIMRVGLLEMVKFGETFFSTAERATFTDESAGVADLITSCCGGRNYRCAKMAVQEGLTVKEVEARELNGQMLQGTSTAMEVHSFLKTRGLEAEYPLFTAIAGILEGKHSVDEIPDLISDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD70</accession>
    <name>A0ABR3ZD70_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LPXTG-motif cell wall anchor domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002018</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000035">
        <property type="protein sequence ID" value="KAL1898310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="531"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="603"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="845"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1068"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1205"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="459"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="493"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="611"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="659"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="713"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="755"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="774"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="798"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="871"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1080"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1221"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1240"/>
            <end position="1265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1291" mass="137733" checksum="E0A758D6BF8A6476" modified="2025-10-08" version="1">MLTGPHFSPANANSSRQNFKLQGSSNSSTGESSSQQTSLHSPFATNTLVATALVLSQTEQPKASTNSPIAPTNVAQTTISSPKSVATANTATTNTTQSSAVFTSSFFSASTSHLDDDLCSQVATATSSSTRLPFLRPQQQDLQSSQTFNALDLDSSHSRNLHLHRQNNNSSKLPTFRFADLVSPPGLLQPLPTSSPQSVEGPLPPSTSATRTLPVAKSHRRGKSENIPPKPSLLFKSATAPVGSLSVELKAAPTVVTTVSASASGLNRVLSPTSTGNSAPQRLQSVLKKPRENPSPKTTRLPPQARSPNQQNHQQETELHEDKTSLTKHQTQSQPSSKKTRARLSTSVVEGNKKPIPILSTASKRPASFPTSPRVTQVTFLEPPAAETPPLVAAKGASNRRSFVSSGTTSSGSRAPPISLRVHRVQAAVEAAGVISPTAGGFPNTAASPKAEVIPPSAKTDRDSLREHAIGHNKSSSDEKRSSVSRPPITIKPTPASPSTSNSAGSTPVVRVPPIRAFRASGTRRSLTLDTTTSLVLPEDNDDSLENANNTKKHTRQAALRALEGHNSDSIPQIMTPPGSGYDFNGDNDDTGDLFLKIAREDNGRNSISSPHEDAGFFSDDQRPRNTANRVSRASHRRPLSTVVPAHATPQSPSRLSRRLSDQQETSRSRGRSNDDTNSMAGPPPPPRTLTYRSIARELSSGASVVGDETGNKRPSNIRSLTSGSRSLVHQDTSPTEGAQHYSRRKPSISEGISLVTSSRSGTSKNGIPYHGRTYNSSPLAQKNTADQLSPHQKQHILEQQQQQQQQQQQDSQGQEGTDSTTSTGGPSTVWDELDDLKSRIHRLELTGKLPNSSSSAMSRVSDDRPATAHTAATTNSGSSPKRVAQNSGTNIAPHTNIVNNDNSSTASSQKETPSLLQAALAQAKPGVSNEVYRALELAATDALGLTTLMGTVGQPGPISSGASTIGFGGASTVTDRQLRRKAEGVVRSLTELCIALSTDSAQRPFSNTILQSIETAHDVPLSPTTIRGFNPIMTHNRASIAEQSPASIPTSPRSISKLEERRNKLLNSPVLPAPRFSAMSPSGPSLSMPGLGPENIQTPTQGRKSALLTSRRRAGTEEPEEQSGRKTSMLLRTRRAGTEEPEDINGRRTSMFIRGRRGAAGSDDEEPRMRPPSRAITEMTQIRPATRSGGDYSANAPAQSIECGANNSNSSAPRRRMASAISSRLGSVPPQSGVPTPRRFLERQMTDREAPSTVEKMHSDERLHRPMSLGHASMLGRTSSISRRATTRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDE8</accession>
    <name>A0ABR3ZDE8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001969</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000034">
        <property type="protein sequence ID" value="KAL1898344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="155"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="397" mass="44137" checksum="0D7FCCEE1BC7F0C7" modified="2025-10-08" version="1">MQGDSEARVRREVFEALKNTRFAVSELSPVSGGHANFTMRGELKVLIEDTRYVLIKHAEPYMRIQPSFKLDLVRFIEKKIEVEALKIVEHMPCDPRLATESNMPVVSSPRVLYSNPVSNTMVQSYFPSGIDLRSYGFSHLSQPGLGKIEREKVMEFGRALGHWLVNLHSWTNSPTNTAAKALAASNVCGPALKQELNYGGLLAMKEKSPAALELLSDETINGVVNQTRRELDSNTHVVHGDFWTGNIVVPDIPISQITQLTGFVVDWELFSLGHLAVDVGQMIAEMCQLYLFRNILGGLDLAVAFIDAYMSDTGLQSQVNKTRPWATLEERDDFAFRALLHVGAHLICVSPMPGVWGSGEELARVATIGAQLIEAAWAKDRAFFEENEAFGGFFKRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDH7</accession>
    <name>A0ABR3ZDH7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pentatricopeptide repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001897</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000032">
        <property type="protein sequence ID" value="KAL1898430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF15">
        <property type="entry name" value="OS02G0120000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="25"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="871"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="53"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="874"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="888"/>
            <end position="897"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="897" mass="100637" checksum="4B802B05FBC7EA3F" modified="2025-10-08" version="1">MTLATKWRPLPRVLLNSPVASTAPVASASSTDSFHASKPLPASTPGLAAQRWSFSTSSSQPASISQQPGPAPAKTNSALQRTRRRRREVSRTGEVSAAPEMLQMQEDMVALASLSAGQSVVVKPLLKYPRPEMTWYARGQHNKSLGTQKYLEKERIKYGSSDDADAMNPDWRGIVATMLATTPKTTMWKGDVVRAVVGATLLDELLSGVDRNIWEIYSRTGCTMDVYPHSKEEQDKTNGQEAGYVVLSGDSNAVRQAMTEIRTLAQGAALTDTTATLRPLGPEEALKIRLTAEGRFTTAYGEKPSHIPALQGRCDAKGLFEEHVPIPAEWTQRSLLNYTAKLAFAHLSHNKTFNLYGTPQARDESRLELMHKAFAAPDACHAVSLAAFKRAIYSALMSGPHKRPHMRILFSKMVDLQLIPDTDVFNMFLEDATKHKDLRKFRSVLWMMANYGCVPNLQSWMQLLRLVEHEEAKRHILRSMHSIGLLYDSRALRSVAREMVFFDAHRAMQGYEPYDDRITNEFINEKKPPDDLLTSMDSSSPYQQQQYTPKIPTQKTICPNKSNVGNLSIPEFISQLEKHYGPNWASVAAIRHVVNVFCMFGRFSAVSTFLARMGWNYKRDPVVYNIILSRARTLGLWKPMLQTLHTMAQAGVPVDEIGYTQLFAFARKVKWPNTQAIVWAYACIADRTTMHMRAAVSCQLRYPGCSMAKDFHIFGLQSEYVVPALVPRELASRFAEASNITAIRTHSHSPNPYWFSSAFNTDLPPSSEAPSTNPIAMRKLGATLVEIFRQETQIEDNKRLVPCISLIDMLTKAYTWDQKLLVKSNNEAATVRLVTNQNWPTLKIPLRTKGTGPVVRTLTIPVVRSKIVRSKSTKNQDKLLQGERGEGEIEEEHEQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE88</accession>
    <name>A0ABR3ZE88_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">3-hydroxyacyl-CoA dehydrogenase type-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001910</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000033">
        <property type="protein sequence ID" value="KAL1898365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43658:SF8">
        <property type="entry name" value="17-BETA-HYDROXYSTEROID DEHYDROGENASE 14-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43658">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="263" mass="27697" checksum="F4AC75B5CE6FD64F" modified="2025-10-08" version="1">MKIDGRTFVISGGASGLGHACAQDLIAHGANVAVLDFNEKLGEQVVKELGDDKARFFPCNVRETESIAGAVKGTLDWVSKTGKPLGGIIPAAGVGFPGLIIDRDGSPLDMSNLEVVIGVNLLGTIDLIRQFLPALSKTTPEGADKERGVIVMIASVAAYEGQRGQVAYAASKGGVAAMTLPMARDLSQWGIRVVSVAPGIFTTAMTAGMTDRVRMSIEKSMEFPRRAGVPKELAALVRHIVENVMLNGEVVRLDGGSRMPSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFH8</accession>
    <name>A0ABR3ZFH8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pre-mRNA-splicing factor cwc26</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CWC26</name>
        <name evidence="3" type="ORF">Cpir12675_001657</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CWC26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000027">
        <property type="protein sequence ID" value="KAL1898997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018609">
        <property type="entry name" value="Bud13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051112">
        <property type="entry name" value="CWC26_splicing_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31809">
        <property type="entry name" value="BUD13 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31809:SF0">
        <property type="entry name" value="BUD13 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09736">
        <property type="entry name" value="Bud13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="256"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="144"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="320" mass="36059" checksum="4AA699530D24056B" modified="2025-10-08" version="1">MSDLSNYLVTHYLVADPAPSKKSKKKKSKGQTGLLITEDDDSSWSQAHITKNGGDEAIAAVAGTSAEFRKKKESSWKVLSSETRDSNSVDAILASVAAETRAAQQGNDEMPAVDNADNVVKMSDGTHSGLQSAAAISAQLKKRQREEREEFERSKQGVEEAETVYRDATGRRIDVSMRRAAARKVAEEAEEKERQEKKALKGDVQLEEARKKKTDLEDAALMKFARHADDDGLNKELKEQQRWNDPMMQFMEPRKEMGKKNLRKGRPSYQGAAPPNRYGIKPGYRWDGVDRGNGFEAERFKALNRRERDKGLEYSWQMDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFR1</accession>
    <name>A0ABR3ZFR1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">U3 snoRNP protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PWP2</name>
        <name evidence="9" type="ORF">Cpir12675_001929</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat PWP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000033">
        <property type="protein sequence ID" value="KAL1898384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027145">
        <property type="entry name" value="PWP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007148">
        <property type="entry name" value="SSU_processome_Utp12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19858:SF0">
        <property type="entry name" value="PERIODIC TRYPTOPHAN PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19858">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04003">
        <property type="entry name" value="Utp12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="197"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="241"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="386"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="428"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="514"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="domain" description="Small-subunit processome Utp12" evidence="8">
        <location>
            <begin position="793"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="598"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="691"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="923"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="599"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="692"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="923"/>
            <end position="933"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1898384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="944" mass="104526" checksum="9C3AC1C5713F527F" modified="2025-10-08" version="1">MFYTNTFDNKRLKWENKSNDHKEITIQKEVYNLTPDTFNSSLATFGLALVIGLCRLFTNLLGQVYCQGNLVFDPEGTHLFSPVGNRVSVFNLVDNKTYTLPFAHRKNISRISLSPRGNLLLSVDDDGVAILTNVPRRIPIYQFSLRSPVTALAFSPCGRYFAAGLRRRIEVWHVPSTPDANVDGQVEFAPFVRHHSHSQHFDEVCHIEWSSDSRFFLSASKDLTARIWSLNAEEGFVPTVLSGHKQAVVGAWFSNDQETIYSVSRDGAVFEWKYVAPLGTSDEDEPSPEDFRWRVVKRNYFMQGSAHVKCAAFHPKSNLLVTGFSDGVFGLYEMPDFNPIHKLSISQNDIDFVTINQSGEWLAFGASKLGQLLVWEWQSESYILKQQGHFDSINALTYSPDGKRVVTTADDGKIKVWDVESGFCIVTFAEHTSGVTACEFTKKGNVLFTASLDGSIRAWDLIRYRNFRTFTAPTRLSFSCMAVDPSGEVVAAGSLDSFDVHIWSVQTGQLLDRMSGHEGPVSAVAFTPDGSHLVSGSWDRTARIWSIFGRSQTSEPLQLQADVIAVAVRPDSNQLAISTLDGQLSFWSIHDGQQIAGLDGRRDVSGGRKDTDRRTAANSSNAKSFGTIRYSTDGSCLLAGGDSKYICLYSVSTMVLLKKYSVSVNLSLQGTQEFLNSKKLTEAGAVGLIDDQGNNSDAEATNASHNALPGSKRGDPSARKIHPDVRVTSIGFAPDGASFCAASTEGLLIYSVDSTLTFDPFDLSIEVTPASTLAVLENNQDYLQALVMAFRLNDDALIKLVFQAVPHRNISLVVEGLPTLYLQRLLRFVATQTEDSPHIEFCLLWIRAVIDKHGPWLMANRAKADIELRVVSRAISRIRDDIRKLADNNIYMVNYLVGQAKAKSSPLTLRAPVVDEVQKVVTEGEDFEMDDSDGSNGDEWQGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG69</accession>
    <name>A0ABR3ZG69_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_001495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000024">
        <property type="protein sequence ID" value="KAL1899302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1899302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="227" mass="25361" checksum="9BC011C8F8D81565" modified="2025-10-08" version="1">MASPKSPSAISKSGYVPMNLARSFLTAKNADVEFVSSEHSSFPAHSIVVENASKTLMSTPKKMGLFPKPSLPVKIQTPYRHDVIELFLEFLYLGKVNDFSPSEDVQMLVSSKIDHTAYDLGAWVEATFAAKTFDVPDFGAAVHKYLLRHICKLIRFSVDEAVDALKLVYGKCKEGQQVEIIPVLLKGIVQEFSLVQENQAFRRFAEENGNFSWDLSQAMNCYLATEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGB7</accession>
    <name>A0ABR3ZGB7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">ATP-binding cassette glutathione S-conjugate transporter ycf1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">YCF1</name>
        <name evidence="13" type="ORF">Cpir12675_001255</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000018">
        <property type="protein sequence ID" value="KAL1899753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18595">
        <property type="entry name" value="ABC_6TM_MRP1_2_3_6_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18603">
        <property type="entry name" value="ABC_6TM_MRP1_2_3_6_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056227">
        <property type="entry name" value="TMD0_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24357">
        <property type="entry name" value="TMD0_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="313"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="450"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="472"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="555"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="588"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="988"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1032"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1119"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1216"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1249"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="327"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="651"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="995"/>
            <end position="1276"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1313"/>
            <end position="1548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="877"/>
            <end position="970"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1899753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1566" mass="173330" checksum="09C6F4A748976B05" modified="2025-10-08" version="1">MGGFSDSLLAWALRSASSQRVLHSGSISGFHPLAPVSHGYMTSTTSSAGGLLRRPFCGNAEGWGPLSPVRYDFTPCFIDVSVMSVALFGVFIGALAVAWLSKRPQTPGVVKDWHFWMKQTILVGIIGVSISQVVLQALSYGKSWYLDFRTWTSAVNIVALCVVFYIQWLEHPRMRSPNGVVLFYWLFLLIVLAIKLRSLVSQHVYSDAPAFFILYCVGMGLCVIEFFFEWLWPRKHSSYEVLIDEEECPLEYADVFSVLTFGWMTPLMRYGYKEYLTEDDLWALARDDNTNTTGALFMKAWNHELKTKSRPNLWLVLLRAYGGPYMLGAIFKIGNDVAQYMQPQLLRILIGFVASYSRKNDGEPEPVIKGAAVALGMFAVAVFQTAMVHQYFQRAFVCGMRIKGGLTSAIYKKSMKLSNEGRSSKTTGDIVNYMAVDAQRMQDLTQFGQMLWSAPFQIIICMWSLYDLVGWSMLAGIAVMIVMLPINGVISKIMRNLQKEQMKVKDSRSRLITEIINNMKSIKLYAWGTAFMNKLNHVRNDQELKNLRKIGATQALANFTWNTAPFFVSCSTFAVFVFTHDRPLSTDIVFPALALFNLLNFPLAILPMVITAIVEASVAVGRITDFLVADELQSDAVIVGPAPTAMGEETVIISDGVFSWDRHQDKDVLTDIDYTAYKGELSCIVGRVGAGKSSFLQATLGDLYKSRGKVEVRGTIAYVAQQAWILNATVKDNIIFGYRYDADFYDRTIRACALLDDFAQLPDGDETYVGERGISLSGGQKARVALARAVYARADIYLLDDVLSAVDSHVGKHIIDNVLGPRGLLETKTRILATNSIPVLREATHITLLRDGCITEAGTFKQLMAMKGAVSDLIKTTGHESSKTSSETSTIAFTDNGKSRAGSDVDEANEDVPEMKPINSKSKAKDKVRSDSITTLRRASAASFRGPRGKIMDEEGSPAKKTSQSKESSEKGNVKLKVYMEYARSNNLVAVAMYMVALVLAQIANIGGSVWLKKWSESNAENGYNAAIGRFLGIYFVFGVGSSALTMVQTLVLWIFCSIEASRKLHEKMATAIFRAPMSFFDVTPTGRILNRFSSDIYKIDELLARTFNMLFVNGARSVFTLVIISISTPAFMLLILPLTFMYMYIQKYYLRTSRELKRLNSVSRSPVYAHFQETLGGTATIRAYGKQSRFEQDNEWRVDANLRAFFPSISSNRWLAIRLEFIGALVILAAAGFSIISVTSGSELSAGMVGLAMAYALQIVTSLNWIVRQSVEVETNIVSVERVLEYAAIKSEAPEIIPDHRPPAAWPTKGAVEFNNYSTRYRDGLDLVLKDITLDIKSHEKIGVVGRTGAGKSSLTLALFRIIEAASGNISLDNINTSSIGLLDLRRRLAIIPQDAALFEGTVRDNLDPGHVHDDSELWSVLEHARLKDHVMSMTGQLDARIQEAGANLSQGQRQLISLARAMLTPSNILVLDEATASVDVETDALLQETLRSPIFSHRTIITVAHRINTIIDSDRVVVLDKGRVAEFGTPADLLKDTQGVFYGLVKQAGLLEGEQGGSSSTEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGZ6</accession>
    <name>A0ABR3ZGZ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_001202</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000017">
        <property type="protein sequence ID" value="KAL1899978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16448">
        <property type="entry name" value="RING-H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052788">
        <property type="entry name" value="RING-type_E3_ligase_ATL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45798:SF97">
        <property type="entry name" value="ALCOHOL-SENSITIVE RING FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45798">
        <property type="entry name" value="RING-H2 FINGER PROTEIN ATL61-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="314"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="267"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="443"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="269"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="443"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1899978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="648" mass="71993" checksum="3FB771CF301EB444" modified="2025-10-08" version="1">MSYQSSYNTNLTTLSTSNAATTHGTLQGLLYVPEISSDHPCYQSQFEDPVLLPRNVTKKTDLPPANYKLIAIAPWYNDTCTHAYLDAARFDPIQGFIFYRPFNDILYEPSESEGTSLWAMEDGEEGWPDNYRFPIYAIPSQYGNDMVSALSQYSGSLNTIPNSDNITAIFNPSQRDYVRIWAQLHVNDHHHSLRLWVYFVIVIASLILVVAGVSAIMHIIQQSRRKQLERRIKSGQVDLEAMGIARVRVPIDHIKEAFPLFTYCQAPGPKSQSTSPRSRSSTISSYSIGKASTVKPEPNVSEYAVVGTNDQPQCEICSVAFENRVSVIRQLPCFHIFHAECIEEFLSHISCLCPLCRQQMLPKGYCPPITNGIVHRELQIHRLRGHVVLDDEEVVAESESLSYNGRTRKHSVSSRTENASLELRDTHIAPKEYGVLKSSNTDVSNTALNSMPTKARPTRRLSGSTNNDNFSTATTINCGSTMSPTLSPTLEIVKCRDFAKTPENPRSFRTHTTISFASNSRAVASSPSTPSIQKTPAILTTPETAFPNTTTDTSTQALVPSPRLAQAPKPPATAKVTKAKRSWQLRKGPAVVLPPRLSSIASSAVAAISPIVEGHKSPGTIRRQRVRQYAQMLREQETEPEGQRRLCM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH00</accession>
    <name>A0ABR3ZH00_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_001204</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000017">
        <property type="protein sequence ID" value="KAL1899980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112:SF5">
        <property type="entry name" value="BOX PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G04550)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="4">
        <location>
            <begin position="134"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="2">
        <location>
            <begin position="134"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="114"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="276"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="279"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="293"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="308"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="328"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="360"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1899980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="378" mass="40323" checksum="1F39058C24409417" modified="2025-10-08" version="1">MARPSKASKEKAAAVIGVSTSNALTMPPNVIPTSAGGPRPPVIDVDNFIRVRDSVYGRLTTIQQLIKSFSDDYLRQTNLLLGLSTPEDGSEDALANLEASMSALSGVSTLILPPPPVVEEKKERKKRTHDPNAPKRPLTPYFLYMQTARPIIANDLGPEAPKRAVQEEGQRRWASMVPSEKGMWNQAYQYNLRLYNARVHSYKHGNPDAKDMDDDEANKYANNNNIQIPNAEAAEQNAMAEQLQAAAAASSGMDAQGEDDGDLAAAAAMGGVIAPGHAHAAHGHPHVHGHPGHPGMPSAAAGVVTPAKTKKPVATGRKRKSATDGDEMAAAMSLAMADSPVLVAGAPTPDKKRRRTSGKPNEDKEEPKKAGRKKNVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH07</accession>
    <name>A0ABR3ZH07_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GPI anchored protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_001259</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000019">
        <property type="protein sequence ID" value="KAL1899679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39599:SF2">
        <property type="entry name" value="ANCHORED PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G09650)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39599">
        <property type="entry name" value="GPI-ANCHORED PROTEIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047248199" description="GPI anchored protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="367"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1899679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="390" mass="40629" checksum="0F3E7179D54E55C0" modified="2025-10-08" version="1">MQFHSIGALAAVLLASSAECWDDLFLPTAVRRMPADAGERFYPDYQVFVAAAPTFMPLAAREDAASVIIDRLYPEFVPSAAVEDTNDGKAWPRQPIFRRHESSTDSQLPWVKFRRAAEVLNLLQGRSGCPSGFNSCSGIGYSDKCCVSTETCVEVDDQTTGNVACCPAGSTCSGAVASCPSSAVSCMKSGQDTTSESGSSTSTDSSSTSQTPITTSSQTTAAAPFRPVSTDETTSDTTSEPTSTTEVLDNCPTGYYPCLARYGGGCCQTGRDCQETSCAPTSMTNIVTRSDLTIAIPVTDMPTATVDASDSCAQGWFLCDAMDNVAAGCCPDNYECGTASCTLSMADETTAVGKQGISSGTPAGPKAGLWSAGTWVCMAMGVGASLLFMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHY9</accession>
    <name>A0ABR3ZHY9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="9">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">KGD2</name>
        <name evidence="12" type="ORF">Cpir12675_001348</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000020">
        <property type="protein sequence ID" value="KAL1899670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004149">
        <property type="term" value="F:dihydrolipoyllysine-residue succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050537">
        <property type="entry name" value="2-oxoacid_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43416:SF5">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43416">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6 9" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="11">
        <location>
            <begin position="38"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="114"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="115"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="137"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1899670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="416" mass="45179" checksum="7EAD71A5EC1F68C4" modified="2025-10-08" version="1">MFASKFSRAAKMVQLHQLRPSRQLPLSLMMQRVQSYATITVKVPQMAESISEGTLRQFSKQIGDYVEADEEIATIETDKIDVAVNAPQSGTITELLVGEEDTVTVDQDIIRIDTDGTAPAGGAAPAKEPAHIEKETTSGAPATAPAPTAPAASTLTDHAPKKAEPSKGPAPAPTSASVGDRSERRVKMNRMLLRMSERLKQSQNTTASLTTFNEVDMSSLIEFRKSMKDEVLKKTGTKFGFMGSFAYACALAMKEFPVVNSSIEGEGTGDTIVFHDYVDISVAVATEQGLVTPVIRNVEKMSILEIERGIAEVGKKARDRKLTIEDLAGGTFAISNGGVFGSKLSTPIINHPQSAILGLHAIKERAHVVNGEIKIRPIMELALSYDHRVTTGREAVLFLETVRKYIEDPRRMLLEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHZ9</accession>
    <name>A0ABR3ZHZ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">rRNA methyltransferase 1, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_001261</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000019">
        <property type="protein sequence ID" value="KAL1899681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18105">
        <property type="entry name" value="SpoU-like_MRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047182">
        <property type="entry name" value="MRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047261">
        <property type="entry name" value="MRM1_MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013123">
        <property type="entry name" value="SpoU_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46103">
        <property type="entry name" value="RRNA METHYLTRANSFERASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46103:SF1">
        <property type="entry name" value="RRNA METHYLTRANSFERASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08032">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00967">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="RNA 2-O ribose methyltransferase substrate binding" evidence="11">
        <location>
            <begin position="337"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="40"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="158"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="655"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="54"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="165"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="208"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="251"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="291"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="666"/>
            <end position="675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1899681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="675" mass="74307" checksum="F387F2DAD96B1BF2" modified="2025-10-08" version="1">MSSMILLQLARRLPYSHAAAPLISGFSQERAASSFSAIHRSVRASSKATGRSFTRHDRTDRMGSRGSGRDSDKRRKQDGPKIKGNDRMSDADFRNAMAKHGSTEEESSRRTRRSRFHDAEEGHGKRSLVYMMKYGPLKETADRILAQKAAEATAASRKALGLPLDEPKTEKHKAERPLRGAPSLGRPAARDINHKGTSFGDKSWQSPFEKRSDSSDRPQRPLYEQKPDKSPFDRRSRDSSLGDRAFSGRSFGHDQERDSRPSTSFSARPQRDRSVYGSSRRPYDDPKVPNFQDSRGSRQFRQSDKARNFDSPTSRQDRGPAIIGSPVVPYTTAASQFIFGKSAVKAALHANRRKMYKLYVYNGDNRQDSPDDALFIALAKQHGIAWELVPTNGQPMMDRMSQGRPHNGYILEASPLPQPPVMSLGKCSNEGSYKSFEVKLGYQTREEQAVNGTGERIVYTGLAKPKPLVLLLHELLDPGNLGGIIRTAHFMGIAAIAITKHSTTTLTPVVIKAAVGAAEHMPVLVVENPTLFVEESQRAGWRTFAAVAPDSRNQSQSATIEVIAEMNPLNEYPSILVLGSEGSGIPRHLRKRIDVDVTIPRLVATSQVDSLNVSVATGLLCHAFMQKRPGDIVQADPVAEAMGMSETTMSAEAVTSALASASEPLDNEKDADQLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI16</accession>
    <name>A0ABR3ZI16_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001039</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000014">
        <property type="protein sequence ID" value="KAL1900355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052973">
        <property type="entry name" value="Fungal_sec-metab_reg_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392:SF2">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="433"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="198"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="858" mass="94316" checksum="F3A1C7D2E242C2DD" modified="2025-10-08" version="1">MGRKPNPLILEYFQRGPKLADNSNRYPHTCRLCGEDFPKGRIDSLTGHITKSGKCPAISETERINACLTLHGIPSVPPVAERLSAGITAHNAVDVASATDTILAQQWSALEALAEASRQVDMSEKHDRPGSALVHVQLSNGDSSGMGNMSGNGLQGADRFDLPDQFTLDNAPSSYDATTAAMAQQSLNSLLSPEFHPDPTSDSPSHSLLTTNTHDTGSTTYAVANGISKPHSPITESLATKDQRDELNNDDQQRQSQELKGNQNNEQHEHHYSHDDLVLSSTDVARLEAASAATDLSVAEAATVRLTNSLLDPQLVASQTAHALPTVHDDHEAQAAHGAQMAQVSHESHVTHSTQQAVQQAVEQAQAQAQADVDAQVQAQAQAHADAVAAVAAAAVAKSNASESHAFQVGDNADWGGMTYVTNKSQPAVARDLSRTPVPGHRGGVRMGATDLSPNGRPKHARARFSAARRKEVQEVRKLGACIRCRILRKTCGKGDPCETCCKVLSPRVWRAGCVRTRLHEQLELYSAGVQVVLAQNRYNMIKNTVQLATGESYIEGSLFPTAESKIILRTFEINTHKEGTPPEQGPEMETRAIMIDCDSEDMPAKIEEYMRQVLPLLIEHEPSPVVRVILTTAIEALNETEDELLRHALELWGLVDIIDRERQWHILEKKPSENLERWIRDPNERLGIDIYSVMLIQLNAAAERKGNTTSRSLLNKMQRYLQDSKVKIGFRMFLTALVFLNCIEKSTWGFRAWEQQNLRGGWPLERQPETFIGQGANLASLLKLLLSCRRVLPQVNRDEETGLLFPNESAGPEFAAFYKNIGVTDETLRTRQEKAEFNPVDSRCLELTLCSQLLLGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJP1</accession>
    <name>A0ABR3ZJP1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinase</fullName>
            <ecNumber evidence="4">2.7.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_001149</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the inositol phosphokinase (IPK) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.-.-" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.160">
        <property type="entry name" value="Inositol polyphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005522">
        <property type="entry name" value="IPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038286">
        <property type="entry name" value="IPK_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12400">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12400:SF103">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE MULTIKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03770">
        <property type="entry name" value="IPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="102"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="180"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="431"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="498"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="373"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="434"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="508"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1900043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="534" mass="58514" checksum="4E2CF6E92A4C418B" modified="2025-10-08" version="1">MPPAPSVGDLKHSDLQAYKAVAGHDGTMCDSSGKLFIKPCTATEIKFYEKLQAPEYEDLRYFTPCFFGTLSLDSKASEAVKQLVDSGVLNKEATEALVLAQAAESEGSQTEEKTGGKAGIQVAAETEPGDKVVELGAELEPEETNAAQPQSSLSPSFVHQDLEPVATVKGHCSSKLLYQSPAHAQSQSQPSPSEILSGASSKSDSASVSDKWVPNGAKRIKTDTALVLENASYGFRHPNILDCKLGTRLWADDAPMEKRRRFEKIAATTTHQNFGFRISGMRAWHGSNDPADLDPDGYMAYDRNYGRDHVTDDTLAATIRRFVFNPSAGITHELARAICAVFAHELEMVYEELNKHCFRIYSSSLLFIFEGDGKELERRIEAHNNDVDRYEEHMDNGNQDLIQALERQKGTAAALLNGDLGSMATLQVGRISDNNEDNSGEEDGDSDGSDDHGQADRTHSLRLIDFAHASFVSSDQGPDQGLLLGVKSLIKLFRDMAKEAETEDENGNEGRDKDRDNANSTDEHVPQNKRARTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKD4</accession>
    <name>A0ABR3ZKD4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pirin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_000831</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the pirin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02910">
        <property type="entry name" value="cupin_Yhhw_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43212">
        <property type="entry name" value="QUERCETIN 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43212:SF3">
        <property type="entry name" value="QUERCETIN 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin N-terminal" evidence="3">
        <location>
            <begin position="105"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="374" mass="40675" checksum="64A43E81657A09AA" modified="2025-10-08" version="1">MRLLSPWSAVLAIFLAIIISTTNYGHTLLDKVTESVASCKSFETTATTTTSTISAFSAFGGSSITPTSTLTSATSLNMSTVSKASNTMSKALRHAKITPHRSSARGHSDHGWLNSYHSFSFADWYSPKFSHFGSLRVLNEDRVKANSGFPTHPHRDFEIFSYILSGELTHRDSMLSKGNEGGESEKFKQMKRGDVQFTTGGTGIAHSEFNEHPSETVHFLQIWAIPWKKGLPPAYHTQTFSEEAKRQAFLPILSPLKAGEDATLADEKEAVPAIPGTIPIHADFVMGAGIIEPGKIFDWRVGAKVAKGTKRKVYIHVTMTKGGKSKIRLDGREDDDAILGEGDGVFIDNLASDDILNVESIGTAEAEIVILDTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKM1</accession>
    <name>A0ABR3ZKM1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mediator complex subunit 15 KIX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000511</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="134"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="737"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="841"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="921"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1165"/>
            <end position="1301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1333"/>
            <end position="1352"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="320"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="142"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="741"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="841"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="864"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="890"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="935"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="987"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1167"/>
            <end position="1190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1198"/>
            <end position="1207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1219"/>
            <end position="1238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1239"/>
            <end position="1261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1282"/>
            <end position="1300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1583" mass="172403" checksum="FFD6C2322CE118FE" modified="2025-10-08" version="1">MAANMHPHMMAQQMQRPQGRAAASSGTQAYILQEISSHQRPTQGWQTAVTNPERTINVFKLFTTMALANEYKDPPALIETCLRYEREIFYHSPDKATYDARVQSKYDDAFARRQNIDPKIQTPVNIQSQMQAQQAQRMAAMNSPQVQAMMQQSMGRGMPATTQQQQQQIQRMQQIQAAQRQQQQQQQQQQQQQQQQQNVGQINFNLGMSNNLNAQPMVPQNSQMIGINPAQSRPAAQPNPADLSQAERAQALEIAMNRFKSMSEAQKDQYRQAMRRTGNPNITTLELQGKDIALMAIQRETISHFTRERNRLRGGMGNNANMFQQQQQQQQQQQQQHQQQQQQQQQQQQHQQQQQQQQAQQQQQVQQQQVQRLQQQQQQQAAMNQQALNIAASMKQMNGINGADFQIDPLTGQPKAGILGQDGGLNQIGLSGPNGVIQTPQQMSAMSNHSGPMANQGPRPNPQVNPMMQNGMSQAQQQQTSTAALLQQRQNQISQQNGPGLGNQSTISPAALAQARLQGQNPQLNLGMAPGSGPQQQPSVMANNGAPFTNNLNPMFNQQQASPGQQRPGLAANTIFAQLLSTMTPEQKARLQNMPQEKLMELVQHRAMQNQRMAMQAANGQPGAGAMGTNNPMNMPQQQNPQRIGNMANGVPTGIQQQRLREQQQQQMDVMELPSIFRNINIPAEVKNWAQLRMWIAKNQTSLPPQLMAIQGKLAEIQNKQWTTFRSMFQRRQMGGGNLTGQGQQQMHQNPMQPGQTPANQSPMGIASGAPSMNLQQGINSNFANRPDLAAQFKSITVSASDLIELRKRYPNTPDDRLRSMYLAIKQKQFLLQQQAGQMTQQSMVQQGQPQQPGLQPGPAMTPLSHSISTPINGQMSFPGPQQSVPMQAQGSQMSQMPRMSPQQPVAQAIAQPIASPALQNGSMAIKPTGGQVPGGKKAAAGGDQASASNRVQRSASSQQRQQRVPDMSPAQGNRNLKRSTPDDALQAPPVQPSQSQQSGAAINNPPDGDAGSSQQGGGQQIKLPPNTNLHISPELKAFRISNLKSIGGETIKSVSGQPVAEIKMEPQHKQKVIGALHILKDQLNRTGKIVPHWYVFSGDEEAIIQYFRGRYRLSAQFVDETSMSFKETLTIDIPEINGYLQSLERMWKGTAAIQVALVAAKNKPQGATPSSAAGTPAALPATVGPSQSTPIPPPPALASTTTGAPSISAHSTSVPGMGASNATTTAPPAAPANGGTAVSMSKNSSNTEFQVPSTSPSGAPSYSKDLKNVNLHLPPRKKSKTASGQVTGGLSQAQPTATAATLRANSSANVGANSSPGQVKLSSPEAVKLTPVATPGPVATPVEMTKTTTPKVATPKPTFPCAESGCDFARIGFATEDMRDQHVDMEHRKHEENPMGYLQESLLEYSERYVASAEQGRNANMSSQAATGKETGTKDVMLSEVDNSTGAPNLFQPLISPTDLFNTLHAAPAEIFNLPDENDFGTPDVLTAESLNEPQELDVDDPLRPIDLALPEDLDTELLQKAHQAEGVLLNCWESHNFAFDMPPDDEDLIGRDMFYGRAEYEDLDLKSLDTLLGSFLPAAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKW8</accession>
    <name>A0ABR3ZKW8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000539</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035213">
        <property type="entry name" value="DUF5321"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17254">
        <property type="entry name" value="DUF5321"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="203" mass="22769" checksum="CEC034CC108B8AC8" modified="2025-10-08" version="1">MPKFLPARLSPLALAVFPRASIGFVPMVELQHIRMSSGSSRLPSIAQPSLWFSMLPKSLRQRRGLKKRNQKSIMERMSANPATFFMAMFILIGSMSINLLGMKNEFATFTRRTDTRICLLKEVIERLQAGEKFDVDRALGAGDEDQEREWEDVVGQFVGGLSSAEKSDTEEKHKNEAAPISTNQPESVTETPSRKNKGLSSFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLL7</accession>
    <name>A0ABR3ZLL7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Uracil catabolism protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000313</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012469">
        <property type="entry name" value="DUF1688"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31687">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31687:SF3">
        <property type="entry name" value="PROTEIN URG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07958">
        <property type="entry name" value="DUF1688"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="536" mass="58813" checksum="7A61FBDB74E2B2DB" modified="2025-10-08" version="1">MGLFSRKKSTGGMAPPVKPSIQTSNSNASFNSGSSSIKSPATSFKPSFNRSSAGSGSPSSPMTSISPTKIDIPRAPDPNIDPAGYLRSLQAVRERAKIMTDKATRNNLTHFDVDISKFGDVVRFVANIIKRDYDAPFHSIPPHCRYQHFCVGGRDRPAHMLATFSDVDNSEKCRRLMDLCVVSIVMDGGAGSEWSYKSLENNKIYRRSDGIAVAAFEMFKSGLFSSNPSNRCQVDKQGMKRLTVETLANGLQSRPGNEIVGLEGRAELLSKLGAALEHDNVFGPHGRPGNMLDYLLSHPSTQASSKLIVPVPLLWNVLMEHIEPIWPQSRSNIHGVTLGDAWPCSSMPKPAVSPNGSPTTFSPFPTGANSPAAWESILPFHKLAQWLCYSMMQPMQSLLKVHFTGAELLTGLPEYRNGGLFIDLGVISLKPKDEARGLENFKKHYDSGSHRAVEVAPLFLTSDDVVVEWRGVTIGFLDRLWHEVNKYLAKELAGNEISLSQLMEAGSFKAGREMAEVSRPNTREPPILIDRNGTIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLN5</accession>
    <name>A0ABR3ZLN5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Oxidoreductase YfjR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_000328</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HIBADH-related family. NP60 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="HIBADH-like_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051265">
        <property type="entry name" value="HIBADH-related_NP60_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580:SF3">
        <property type="entry name" value="6-PHOSPHOGLUCONATE DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G11600)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580">
        <property type="entry name" value="OXIDOREDUCTASE GLYR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase NADP-binding" evidence="4">
        <location>
            <begin position="6"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyisobutyrate dehydrogenase-like NAD-binding" evidence="5">
        <location>
            <begin position="176"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1901638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="308" mass="32378" checksum="9BEFF3F787CE7CBE" modified="2025-10-08" version="1">MAPRLFWIGLGNMGRGITKNIVAKAKLDAPLLIFNRSPQRCADLAATLPSGSIEIANSVTEGVAAADIIFTCLANDAAMTETIDQALSGPTPVTGKTFVDCSTIHPDTTEAIAAKVLAAGAQFVTSPVFGAPAMADAGQLIAVLAGPKEAIARVKPYYTGVMARAEIDLSDRPYSAATTLKIIGNTFILNMIEQLAEGLVVAEKSGLGTAPLQELVNQMFPGPYAAYAQRMVGGDYHQREEPLFAVDLARKDAGHALNIAKKAGVRLANVETADAHLVQVKEKAGEKGDIAAIYGAVRQESGLKYENI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLR7</accession>
    <name>A0ABR3ZLR7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Palmitoyltransferase</fullName>
            <ecNumber evidence="11">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">pfa5</name>
        <name evidence="14" type="ORF">Cpir12675_000807</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DHHC palmitoyltransferase family. PFA5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="11"/>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883:SF23">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11 14" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="39"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="258"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="13">
        <location>
            <begin position="177"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="426"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="451"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="461"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1900793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="481" mass="53988" checksum="3759C479ACAED31C" modified="2025-10-08" version="1">MIVTQNYKLLQNADYLTMKPESDNSLSRTRCQAKWMTRLVPFVIAGLVGFGIYAAVFHNCINYILRKRHKNAPAIVLLVLLFLFLFLAVCCYLRTFDIVKTNPAIVPLLAARDDENDPSPVQTEKKPRVLCRSNGRLNPPNAAVEVEHREDENERRFAEPEWFYTKSVFVCESDGLPRWCSECRQRKPDRAHHSSDLGRCVYKMDHFCPWVGGVVSETSFKFFTQFNIYCAAFCASVLSCNAYGVALRIDRNEGSDAVSIACIVVSSFFGIFCFLMACTSLRYVLMNQTNIDMMKRGMSFHLAVLMDPSKLPTTGPGDSPELSPKYRTKTYPLDAACDLFPMAPQSAKLPNAPNIGTRTFAILRAEPKENPWDLGWKRNWQQVMGYSILDWVLPVKMSPCALHNNPDSEYPVGPLVEELRRRYQLPSAEMDSTETRPSNDGAEGTTPIYISGSTSASQPVSLSGGLSSHSSAIRPDNRLAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM16</accession>
    <name>A0ABR3ZM16_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_000243</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PA-phosphatase related phosphoesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03390">
        <property type="entry name" value="PAP2_containing_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043216">
        <property type="entry name" value="PAP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165">
        <property type="entry name" value="LIPID PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165:SF154">
        <property type="entry name" value="PAP2 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G09730)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="303"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="8">
        <location>
            <begin position="80"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="8">
        <location>
            <begin position="268"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="213"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="371" mass="40909" checksum="24A88664980B7489" modified="2025-10-08" version="1">MNGLTPNKRPFALDNPEISYPYTENETVPPVALFLCNSLIPSFVIFIVCLVFVPGRTVPKGTPKNLIWRRKLWEMHIGFLGMALSLFLGWFVTNGLKNLEGRPRPDLLARCQPDIKNVAKYYVGGYRLPNTSNSTYLPGHLVSADICTNKDHEVLDDGFRSFPSGHASSAAAGLIYLSLFLASKFSVTIPYLSPSDLKDPLVSYHAFPSRTVSAAPRASDPSGSKAEGTRHDPNDDGIELIAPYPTGGANKRDIAHDRMVTAVRQQAAAPPLYLLLLTLLPTFTAIFVAASRWFDFRHHSTDIVTGFLIGVVSAFFAFRYYHMPISYGGGWAWAPRSKDKAMWAGIGSCSYATEREPLAYRQPGDAESGMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM23</accession>
    <name>A0ABR3ZM23_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_000545</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053157">
        <property type="entry name" value="Sterol_Uptake_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784">
        <property type="entry name" value="STEROL UPTAKE CONTROL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784:SF5">
        <property type="entry name" value="STEROL UPTAKE CONTROL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00755">
        <property type="entry name" value="AFLATOXINBRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="117"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="42"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="58"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="466" mass="51972" checksum="303D7B8CBD222E99" modified="2025-10-08" version="1">MPRDIVREAQLAELRQTWVKLENAVSQPLETNHFLLMADHHLHQQQQQQSSPPPTSTPKPAASSTPLPATVASATGLSRASASTPPPASGSGNTTASGSGSAVLGVSRRTHPKSRTGCRTCKIRKIKCDEERPSCRNCIKHGVTCPYITPSSSATTPSGTISAAASPIPASLLLPHGLSGLHGDHDLNLVDLELLHNFTTSTYATLSSDPSVRNVWRITVARFGVQCEYVMRSILAVSALHIAHHKPQKRDFYFSRALAYHQLASRAATPLMTSLATSNEGWDEAFPPWIFLLSGSKSLICLSSMRIEEYDGPLSPLFIHGKRRWDMYYDRKCSPTLQREISELEQRITSTVMDPVARTIYVSIIHDLARNIKAFKSTDVPYMPDITDPFVWVYSDLGPFLVHLRAQTQESIVIMAHFAVMIRSLENHWWLEGWSFLLLAKAWDMLDEEHKLWIQWPLEQVGWIPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMI0</accession>
    <name>A0ABR3ZMI0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3',5'-cyclic-nucleotide phosphodiesterase pde1</fullName>
            <ecNumber evidence="2">3.1.4.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PDE1</name>
        <name evidence="2" type="ORF">Cpir12675_000493</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.17" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07735">
        <property type="entry name" value="class_II_PDE_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000396">
        <property type="entry name" value="Pdiesterase2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28283">
        <property type="entry name" value="3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28283:SF1">
        <property type="entry name" value="3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02112">
        <property type="entry name" value="PDEase_II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00388">
        <property type="entry name" value="PDIESTERASE2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="543" mass="58271" checksum="E487AA15DDB6964D" modified="2025-10-08" version="1">MLAPNEAPALQVIVLGSGGGPLESNTTAFLVRSVASGWSKGSIVAVDAGVHLSAISRILEETQPNSLGADVMLPHTLEKGPFAGLELQNKSALANGARITHDLVDTYLITHPHLDHISGFVVNTAALSGARPKKLAGLPTTISAFKKHIFNNVIWPNLSDENNGVGLVTYMRLVEGGNPALGEGDGKGYVEVNDGLAVKMWSVSHGHCMERHSHRGSTSSQGGFGSGGSVDAGRGSLLHSTTVNGTSHIKNSISNGSSHTSHHNGLVRPSGLINQATALAAQSCECRERICVYDSSAYFIRDVATAREILLFGDVEPDSLSLSPRNHQVWLEAGPKIAQGNLAAIFIECSYDNSQADERLFGHLKPVYIMEELQALAEQVRAARVDNSVQRESRKRKREHNSILTTVKQRKPPPPPFEDQDPVSPKSMRPVSHVAIATPEGSRTSHISSPVSELSLLDDVEALPGSLSPLPPAIQNGDTQTHIDSKSDFPLRGVKVVIIHMKEKFTDEGDVSVTIKKELDELEAAFKLGCEFIISYSGQSLYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMR0</accession>
    <name>A0ABR3ZMR0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ECM16</name>
        <name evidence="10" type="ORF">Cpir12675_000391</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DEAD box helicase family. DEAH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17982">
        <property type="entry name" value="DEXHc_DHX37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF99">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX37-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="407"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="608"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="138"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="692"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="147"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="218"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="229"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="255"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1901700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1231" mass="136396" checksum="6C42A13D019C60B5" modified="2025-10-08" version="1">MPKFVPRQRKHKVLAREKAAANAVHIYNPNAEELTPLDAAKKRELAEAKAALLVKGTKVSSKKAKRLEKYIEKKLRKDESRVLIQKLGESKIDTSLFAKTSAIGQAKETKRQTLQRALQEEKAGILNGDSKTILYQEREEVDVSEAPEVKKVLESDEPKMKRKKSKGRGGKPNTKEEEEDKEMVDAKPESGPEATSEVIPEVPETAPAVLSVGSGLKRPLETDDDGRPVLKKRQKRRGVATKHSLIYLKPQVVGENEDDDEFEGFDDEDGESDSSEEGSEIEEDDEEDEEEGEEEESSDEEDEDSNDGDSEIGPEENKQRSSSFRAWALQQRNEALGFKPSTEASYLEFPTVQGFVPRAPESDPLPRELQPTTNLERKVYSVTVRRPEAIQEARMKLPVVAEEQRIMEAIHNNDIVVVCGATGSGKTTQIPQFLFESGYGSPESPTPGMIGITQPRRVAAVSMAKRVGEELAEYGARVGYQIRFDGTVDSKTAVKFMTDGVLLREVAQDITLAKYSAIVVDEAHERSVNTDILVGMLSRVAKLRRELADEDKTGATKPLKLVIMSATLRVDDLIKNPVLFPTPPPVLEVEGRQHPVTLHFSRRTHADYVEEAFKKVSRAHRKLPPGGILVFLTGQNEIAQLSKKLKAQFDSGASSGSAPKVKVLASEAVLEAEDIDLGDVDMSEMVDDMVYDSEDEEEEDGDEDEFKIEDDNEDAPPKIKVLPLYSLLPTREQLRVFEPVPEGTRLVILATNVAETSLTIPGIRYVFDTGRAKERRFDRLSGVQSFDIGWISKASALQRAGRAGRTGPGHCYRLYSSAVFERDFDAFSQPEILRMPIEGLVLQLKAMKLHNVVNFPFPTAPSRSMLAQAERLLEYLSALTAEGSKITSLGTTMSMFPLSPRFARILLVGHLHDCMPYTISMIAALSVGDIFIPESHVVPQEPEANADGVVFNDGRDDERTALRKKFNATHHRFCHLDERSDAIKLLQVLGEFAHVPTEAWARDHFVRYKALAEATQLRKQIVSLLQKYIPAFANLRVVDKLPPPSEKQVTALKQMVAVGFVDQIAIRADLSPTPPEIRRKPRRAIDVPYVPLVPLNDGPSGANNADPLDSMVYLHPSSPMAHLSVAECPEYVVYGHLQRGAAVAIGSDKTPKTRMHPLTDITGAQLATIAKGTPLLSWGKPVKEVGAPTATEREVWVVPYLRAEGTGGQGWPLPIRKVKQKKVAGKEWVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMX1</accession>
    <name>A0ABR3ZMX1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">ER membrane protein complex subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_000152</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the EMC3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008568">
        <property type="entry name" value="EMC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002809">
        <property type="entry name" value="EMC3/TMCO1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13116">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13116:SF5">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01956">
        <property type="entry name" value="EMC3_TMCO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010045">
        <property type="entry name" value="DUF850_TM_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01415">
        <property type="entry name" value="DUF106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR010045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="257" mass="28662" checksum="DE674ABAEADA01F1" modified="2025-10-08" version="1">MAYPVPQTIHRDPQLFYWILVPITIVMVLTGILRHYATVFLATPPKKLEPLAIREQRGLQQGIATRTNFYVLSKKSFDTRRDALISAFEAGAFLKDPEKNGQPPANPLTDPSAMDGMMGMMKNNMAMIIPNTLIMSWINAFFSGYVIMKLPFPITIKFKSMLQAGVATKDMDPRWMSSISWYILCIFGLQPVFNFILGSNNAANQMAQQMGGAPPPMFGPGQDPDKQFKAEAENLAVVDHYSVLDGVEERLLASILV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN35</accession>
    <name>A0ABR3ZN35_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Proteasome activator BLM10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">BLM3</name>
        <name evidence="14" type="ORF">Cpir12675_000003</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the BLM10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032430">
        <property type="entry name" value="Blm10_mid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032372">
        <property type="entry name" value="Blm10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055455">
        <property type="entry name" value="HEAT_PSME4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035309">
        <property type="entry name" value="PSME4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021843">
        <property type="entry name" value="PSME4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32170">
        <property type="entry name" value="PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32170:SF3">
        <property type="entry name" value="PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16547">
        <property type="entry name" value="BLM10_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23096">
        <property type="entry name" value="HEAT_PSME4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16507">
        <property type="entry name" value="HEAT_PSME4_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11919">
        <property type="entry name" value="PSME4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-0647">Proteasome</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Proteasome activator Blm10 N-terminal" evidence="12">
        <location>
            <begin position="58"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="Proteasome activator Blm10 middle HEAT repeats region" evidence="11">
        <location>
            <begin position="391"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="domain" description="Proteasome activator complex subunit 4-like HEAT repeat-like" evidence="13">
        <location>
            <begin position="1385"/>
            <end position="1583"/>
        </location>
    </feature>
    <feature type="domain" description="Proteasome activator complex subunit 4 C-terminal" evidence="10">
        <location>
            <begin position="1878"/>
            <end position="1966"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="942"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1855"/>
            <end position="1875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="949"/>
            <end position="964"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF11919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF23096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1902106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1966" mass="223452" checksum="4208B70F711B753D" modified="2025-10-08" version="1">MSDHTDAIDPQRGLPIHTSSAMKSPAASTATLATMDDSRLSPGNNPSSSAASIVFDNRRYRPRTFPYDKHLPYLVEDEAKRDAALRHICNKLWLSLKAGDIVPGAVRWTRELQAWLNLKFEMPREQRAQLVRLYYELSLSPGLENNVADRFTRMIVGLTRQMHYLKPAEDLVLPWRPIWRDIKALVLSNELPPHQSSRRRSAKLIWRLISSCRPFFDPGERLAMLNEMLPFFSNSDMPNAYITAGCLAAMIPSRHKDQPISGMEPEDIFPTFFHIWGLVPRSKVFDIFFIDLLSYFARDYLTCNHIEFGSHGIFTSDQSNWIFTALLRLTEIPVGQSMSAYSGIDFHAGIGAYMERDQKKWPPSYLVARLIVNSLSPKALDSDGPSLLSSLEGFIQSIDTFFHPSNLGSWSGFLSQLTAYLADAFVLRWNREQSGELEVPEDRRITTELKNRFVLCLRDVTFMGIYSKGARLSNYYFSALQSLAYLCPDLILPGSLQRFYPSLQGLVEVHRTSSSLSGLLVLANTMSKQKGYRCHITALLALALPGIDANDLNKTSHTLSLIQSIGYSIPIQPLAGVGIDSPIHDTELAMQWVQSQMEIMEAEGTNVQLNYDQMSDEEEMNILRSSTAGFGEFVLALLGKVFTLLENLPDASTVRSGTPEESIINLLPSALSPIFSSLSPELFDQALHKISNFVSSHVVHQARDSMAWILSSLCRVNTEKTLKQIIPMCIASIRNEIDVNNAASDRNSGSEILPRDRALVWYITLLGQVTVYVGDEILKYQDELLELVEYMQTNCKGLPTLHISNLIHHLLFNVTTIYPKEFGLYEPSVMKRGLDVTDWGTLTTPSDLVVDWHVPSDAEIEFAIKIFETQANTATKKISSLMGPDSPIPRTGKNKEWSDEVDRLLSQTLMVISGISTLFDPKRATEANVDSDAAAAADMDAHDHASEIDVGEDEDDPLAEMDGDDGEPRLHFQYNFGYLLKRDSEAYSKIHKIRDDLGRLLSRIHRFLTDNMEDDVSCFQTLYALYRVWITDVGFERSARPLERHNRLYKTEVGSFRIPGLRKQYPRPLLIKRAEGYMLHRLRYGASVRRAGPIDKKLLLDLTESCLSVYADVRRTAQSSQESALKVLTNAKQVVIPKIVDRWREAIRSEDHARIKGGMYTLFFSPLLSSIFKDWRYAPEVVRLYIDTATIDTSSIQELGAACIYEFADFGKQVRRICNIDNKFLEPFKPEEDQSQAIQDLQGFIALRREKIEEAKAGLGLELCKRAENAHWRIASRCTLFAANLCIRFDSLAPKAFIDLTVNGSNDLHPTLRSHYSLALCTVFQMIDMRAAYDHCFINYLNEKAVNTGRVELEVDADDPDWTDNYLKQFSNPDSQYRIDSDYPGWLVWGKKVLVHEAKPPPFDNYDELERSVRDQIGTLITPEWLKTCFNYMKQEPRDQNSDRFRLSNTYLLMHVFDLMYYGRTVVKMDDVIKLIAEVYEDGSDRNQHRATSEILAALLSGSADDPEEFRKKVWTFAAPMLLKILDEDLTPENLSYWTSCVHLIIDSKDPRRAHEIFKALTSFRLDLSSNAAFKEASKIRLLEILVASAGWHFRKDAAITEDFVAHLDHPYKTVREAMGRVLAAISKTRYHESYKDVVSLLKANKATSSLGVRPYDPSEKFNSMITSVFSRLEKWRKERAPGQQTQSSYTSGSKTVLTWMEGILSSQSCTMLIPYFSQLFLDQFLHMLDVKEDPELMKTSSYVYRQLPNVPFRDGQDVEFIEALIRISTGATSWHQRLRAILNIQVFYFRRIFLIHSEQRNRIFDAISNMLEDPQLEVRQCASSTLAGMIRCSPQRIRDPLVVILKKRYQDNLRKNPMPKKKAPGTETPANSSQQIIRRHASVLGLGALVEAFPYASPPPVWMPEVLAHLATRAANDAGVVGKTTKSILSDFKKTRQDSWTVDQKSFTSEQLEDLEGVLWKTYFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZND8</accession>
    <name>A0ABR3ZND8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Vacuolar protein sorting-associated protein 62</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">VPS62</name>
        <name evidence="3" type="ORF">Cpir12675_000115</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009291">
        <property type="entry name" value="Vps62"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48172">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48172:SF2">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING PROTEIN 62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06101">
        <property type="entry name" value="Vps62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="592" mass="67502" checksum="78BA0E2345822D4C" modified="2025-10-08" version="1">MGRSLSLSRLRYLIFFGLLFFSASLGTWLIPRVLNPVPPTGEKRRADRQWIGSSHYWLDRQACRWLSLCGIQHIRVDPPGGKHSILPTDHSNRLSLELRSLVEDQNQTYLAPENMDEYDDPSAFYDADEPIQLDDLEGDEGSPSALYHSWQMAHKPSLPRPKLNSSQDPTSGTILRSVPQYVFDHAPLVHLYSNEHFWPSDIEEHVRHMHVTVDTHGNGMNPVAPAEPLSLDTLSQLNNLSETNKVFLASVDDVEGRPTWLFNSAGRPGEWDDSDDESDPSHDDPGHGHPDPKMHAKIPHDEQWLQEGTTWFDVKPTEPLNRITDPRRLPGSMKKHYRRQSSSGQQRLEADEEKDGERGKPNSNGYSSAPATLIVVDKGSGIVDAFWFFFYSYNLGQTVLNVRFGNHVGDWEHAMVRFENGVPRGVFFSEHEGGQAYAWGAVEKRGSRPVIYSAVGSHAMYAMPGLQPYILPFKLLKDVTDKGPLWDPAQNSRMYFYEYDRPEPENSMANPNCLTPAMQNPDAPVDWFFYTGAWGDRLYPLADKRQWRLFSQYHYVNGPTGPIWKNLNRERMCQTKRCVIAHSLMPGRTWYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNW0</accession>
    <name>A0ABR3ZNW0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">COP9/signalosome complex subunit Csn2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CSN2</name>
        <name evidence="3" type="ORF">Cpir12675_000290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050871">
        <property type="entry name" value="26S_Proteasome/COP9_Components"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10678">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="2">
        <location>
            <begin position="260"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="482" mass="55508" checksum="4BFAB89682C0EB85" modified="2025-10-08" version="1">MSDDDFMQESDEEQYDFEYEDDDEDEEEGGDIDIENRYYNAKLLKQTEPSDAITEFLEIRNHEPEKGEWGFKALKQAIKTEWPLDKYKEASEHYAELLIYVKSAVPRNYSEKSINNLLDYIEKRAGNSEALSEIGNFYALTLDTFQSTNNERLWLKTKIKHVNFLLRMKEYTKAQSILKELHRACRKPDGTDDPSKGTYAMEVYSLDIQLNSELKNTKQLKHLYERALQVQSAVPHPKVMGIIRECGGKMYMGEEQWVLSRQDFFESFRNYDEAGSLQRIQVLKYLLLTTMLTQSDINPFDSQETKPYKNDPRILPMTELVDAYQRDDIHAYQAVLDKNKDILEDPFIAENIDEVTRSMRIKGVHKVIAPYTCMRMSSIAATLRISVVDTMDIIGFLITSGDIKGHIDEQAGTLHIDTQDNADRLADVMELSEKLESLVQVTISELELGRGGLELLGEATMTTESSRRLNRVMQSGGRNGYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP11</accession>
    <name>A0ABR3ZP11_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LCCL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_000442</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.20">
        <property type="entry name" value="LCCL-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051957">
        <property type="entry name" value="CRISP-LCCL_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004043">
        <property type="entry name" value="LCCL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036609">
        <property type="entry name" value="LCCL_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31331:SF8">
        <property type="entry name" value="LCCL DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G02970)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31331">
        <property type="entry name" value="LCCL DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G08630)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03815">
        <property type="entry name" value="LCCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00603">
        <property type="entry name" value="LCCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69848">
        <property type="entry name" value="LCCL domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50820">
        <property type="entry name" value="LCCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="430"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="461"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="LCCL" evidence="3">
        <location>
            <begin position="194"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="669" mass="73961" checksum="159A9CDBCA3B7F22" modified="2025-10-08" version="1">MTTSEADRSASTDDRSVPAFTDEVGFESDAPLSQASVAGLHNPHNYAANLDLGPQIDSDVVPVWRQAQKKPAWVPYSVFRLWMAWLRWAEGPAVPRDYKITPYFPAVQEFPLFLVDRLLPRPRQRASALGLLLLGWVLVFTMIKRNELFSTDIAGWGDPQPISCGVSYWARGNMCGLNGADCRPFNGSGFPFRCPANCLDYHLLNPRAVGDQEIVYRPLVVGGPSRDEESPVYRGDSFVCGAALHAGTISNEKGGCGVVKLVGARQSYTSSKHNGIKSVGFDAEFPLSFTFLDVECSSRDMRWSLLVASLAFSITISLFTSDPAAFFFSIFVGLYWHIGLASDPPPHYSIADLVSKQIAKFVPAMFIAWVFYDQMGVKHTLTGLRAQVEKTALWLGGCWIGALENHTLEWIPINRLEAHDLAQQPGAKTALALIILFLIVVSAGQIHCLRVEGRLIKYLRLYGLFIAGILALLLMPGLNLRIHHYILAMLLLPGTSLQTRPSLLYQGILVGLFLNGVARWGFDAVLQTPTALQGDAQHNSLLPTILAPEIVSLATFGLNMSKLTFRWQSPPSDIYEGLSVLVNDVERFRTFFDGGIDSQSEFTWNRDAGAEIDEYFRFAYIEGNHVLDYTRAGVWTKAGTWRHMDPGPSSIGASKVAGSSEEELYVQML</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPM3</accession>
    <name>A0ABR3ZPM3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Niemann-Pick type C-related protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">NCR1</name>
        <name evidence="13" type="ORF">Cpir12675_000011</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the patched family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1640.10">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053958">
        <property type="entry name" value="HMGCR/SNAP/NPC1-like_SSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053956">
        <property type="entry name" value="NPC1_MLD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032190">
        <property type="entry name" value="NPC1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45727">
        <property type="entry name" value="NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45727:SF2">
        <property type="entry name" value="NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22314">
        <property type="entry name" value="NPC1_MLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16414">
        <property type="entry name" value="NPC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12349">
        <property type="entry name" value="Sterol-sensing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82866">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="592"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="631"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="661"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="713"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="738"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="826"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1079"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1124"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1194"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1224"/>
            <end position="1247"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="12">
        <location>
            <begin position="589"/>
            <end position="763"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1902114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1287" mass="140575" checksum="FC1AAFEC0CAAA78D" modified="2025-10-08" version="1">MASLMSSSLAVTPSQPAGFSPVSTFLTPIHESGRCSMRGQCGSKSWFGKQLPCVDNGLAEDPDAETRKILVDLCGPKWSTGPVAALKSEMSTPNQIIGSCPACKDNFFNLFCTFTCSPDQSLFINITQSMSKAGKNMVTELDQLISHEYGSGFYDSCKDVKFGPSNSNAMDFIGGGAKNYSQLLKFLGDEKAVGSPFQINFPRPETYSEPNMAPLEDMKNPKKCNDEDPSFRCACVDCPEVCPALAPVKEADSCHVGKLPCLSFASIITYSILLFSFFGIVFGRVAWKKHATRRIERHRLLQDTRTSDDEDDEDPFLRNSGFLDRPQRYHKINTWCDSAFSRLGHFAARFPAITIVTSVVVVAILSCGWVRFDLEREPARLWVSPTSEAAAEKAFFDQSFGPFYRAEQVFLVNDTLPSGPGPVLSYSTLVWWMGVENSIAELKGATYGTTLNDVCFKPLGDSCVVQSISGYWQGDTNLVGESSWQSYLEGCTKSPVECRPDSGQPIEPDMVLGGHGNKSVVEANALIATWVVTNAEQGSPQVQKAIDFEIALRDRLLEAQKEASERGLRLSFNTEASLEQELNKSSNTDARIILISYLVMFLYASIALGSTTMSMHDLMRNPSIALVQSKFTLGVMGIVIVLMSITASIGLFSWFGLKATLIIAEVIPFIVLAVGVDNIFLIVHEFERVNISHVDDMVEARVSKALGRMGPSILFSALTETVSFALGAFAGMPAVRNFAIYAAGAVFINAVLQVTLFVSILALNQLRVEDHRADCMPCIQIKAARIHSSSANHIATRYYEVPEESLLQQIIRKHYAPALLVRKTKTVVIGVFLAMFAAGIALLPEIELGLDQRVAIPDGSYLIPYFNDLYDYFEAGPPVYFVTKEANLSQRAQQQHVCARFTTCDSMSLGNILEGERKRSDVSYIAAPANSWIDDFFLWLNPALGDSCCVSSETGDACFAGHNPPWNVTMEGLPEGQEFVDYLQRFLAAPTTEDCPLGGRASYGSAVVIDSKTEVVKASHFRTMHTPLRSQQDFISAYAAARRVAKDISRETGLDVFPYSVFYIFFDQYASIVTLTAKLLGAAVGLVFVIASVLLGSVVTAAVVSLTVVMSVVDIMGAMALMGVSLNAVSLVNLVICVGISVEFCAHIARAFMFPSRTLMQLAQPRFGSSNAANGNSDGDARAWTALVNVGSSVFSGITVTKLLGVSVLAFTRSKIFDIYYFRVWLALVVFAALHALVFLPVALSIAGGEGYVDPESEGGIEDDLAARRFRALERDDDSDYDSEDDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQI2</accession>
    <name>A0ABR3ZQI2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000283</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="472"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="656"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="806"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="944"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="389"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="472"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="527"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="556"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="583"/>
            <end position="595"/>
        </location>
    </feature>
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        <location>
            <begin position="661"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="674"/>
            <end position="683"/>
        </location>
    </feature>
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        <location>
            <begin position="684"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="708"/>
            <end position="723"/>
        </location>
    </feature>
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    </feature>
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        <location>
            <begin position="767"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="812"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="824"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="945"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="962"/>
            <end position="971"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="971" mass="103693" checksum="D34098798DBF6D52" modified="2025-10-08" version="1">MTMHHDTHDLPRVAKVAVTRRTTIVSSDSPYRPTYSTTPNTSGSKGSYFPTVTATVTAGASASPTASVTAPPHSHSLPSITATSPSRPSRPSSPPPVSMISQFGSPLPKHRARTRPSTSSAASSASVIAAIRPRSSSAKGKTTYAPLQADSPFPQRTIRPSSSASLLLEKTANSGINSSSASNATNSNSTTDSATTNTNTTPASGLPRIPALPTGPTSKEEKRLGRIIPVAPGPVPPDERPDYGWNQPAGVIAHFNAKADTVAARGGDKSKSASWTQGFVEKGAKGSAIASAESEKKRWSSSTLARLKKWSKPLTMTHSKYTMQVEAYLKQQRDYEAQRIADENQPPIKLPDTAVAGTTIAGHRYIAISIPLEADPFSPCLSQNQSNGQPAQLLSSSSSQQRQQHHHQPQQTPQKPCKPSPHRGPLSQHPLSLSPPPSRPRVSSLSAITTQSTAAAAASGASTATVADTNAAQPAGSMQSHLPQPDTQVSTGRRNAIHTPSQSIGNESSVSRPATESGSDSGSNTYADSVTTANTSATSTPTISESGQRPGMVPRRSTSMLAQIKQQQAMSMSMAKDANKDITVTSTATSTTTTVQIPRRRNGTVSGGFARTTESIDQVILDGQSISLQSAYPRPVRPVPDIPPIAAQKAKLAQMQAARLVAERDEPERDVPSRNKTTGGSMHSASSSKTSLQLPSSRSRQHDNVAKATSNSAAPSVTSSSANSRRENKTLSSTESTRAKASTEWRKNRQERVRERKMRDIERARSVRSQGSRNSVESPLESGLAPSISSVMVIVDLTPHQVPSISKSAPALEDKAHGKELSRSKRRFKKMRKLSGSSDSDSDSERPDSRGSVAETVMSTASAPLARHSHNCASRRTVQSYDLHDMERRLRKLELSSGGNAVVKALEPALANLDRTLMTLYEGRVVEWMTEAAEKRRSRIVMETLESQSNPRTPESSVYGERTFRLSRGPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YAK8</accession>
    <name>A0ABR3YAK8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000507">
        <property type="protein sequence ID" value="KAL1885340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047483444" evidence="1">
        <location>
            <begin position="19"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1885340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="55" mass="5861" checksum="D8628671763B7B1E" modified="2025-10-08" version="1" fragment="single">MQYWAVTLLLAFAASAMASRVGGAGPAPKYDYGPGLVYSDCWLSGELCRCKNNEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YCK5</accession>
    <name>A0ABR3YCK5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Golgi to ER traffic-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">GET3</name>
        <name evidence="11" type="ORF">Cpir12675_006895</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the arsA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000409">
        <property type="protein sequence ID" value="KAL1886045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02035">
        <property type="entry name" value="ArsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03112">
        <property type="entry name" value="Asna1_Get3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025723">
        <property type="entry name" value="ArsA/GET3_ATPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016300">
        <property type="entry name" value="ATPase_ArsA/GET3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027542">
        <property type="entry name" value="ATPase_ArsA/GET3_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00345">
        <property type="entry name" value="GET3_arsA_TRC40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10803">
        <property type="entry name" value="ARSENICAL PUMP-DRIVING ATPASE ARSENITE-TRANSLOCATING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10803:SF3">
        <property type="entry name" value="ATPASE GET3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02374">
        <property type="entry name" value="ArsA_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <keyword evidence="7 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ArsA/GET3 Anion-transporting ATPase-like" evidence="10">
        <location>
            <begin position="26"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="33"/>
            <end position="40"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1886045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="338" mass="37360" checksum="9835FCB2B0FF74F2" modified="2025-10-08" version="1">MSSALIDADDVMEPTLQSIMDQRSLRWIFVGGKGGVGKTTTSCSLAIQLAKVRRSVLLISTDPAHNLSDAFNQKFGKEARLINGFTNLSAMEIDPNGSMQELLAGQGEEGDASGMGGMVQDLAYAIPGIDEAMSFAEVLKQVKSLSYETIVFDTAPTGHTLRFLQFPSVLEKALAKISQLSSQYGPLLNGFLGAGGQLPNGQTLTEMTEKLESLRTTISEVNSQFKDENLTTFVCVCIAEFLSLYETERMIQELTGYNIDTHCIVVNQLLFPKKGSDCDQCTARRRMQKKYIGEIKELYEDFNVVKMPLLVEEVRGKERLEKFSEMLVHPFVPPEGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YCM1</accession>
    <name>A0ABR3YCM1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Dihydrofolate synthetase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_006941</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the folylpolyglutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000441">
        <property type="protein sequence ID" value="KAL1886007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="entry name" value="Mur ligase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="entry name" value="Mur-like, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136:SF0">
        <property type="entry name" value="DIHYDROFOLATE SYNTHETASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="FOLYLPOLYGLUTAMATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="MurD-like peptide ligases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="MurD-like peptide ligases, peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01012">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1886007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="424" mass="47033" checksum="212EA392C03907D0" modified="2025-10-08" version="1">MAGRAQTIRLGLSRMERLYDANKQSWKAFHVAGTNGKGSICAYLSALCSSSNISNGRFTSPFVHHPSDSIHINGKPISAQEYLEHENFIRLLPGFNDDPPSPFEMMTLIAFRAFAENKVSYGVVETGMGGRLDSTNVMRQKSVNIFSRIDMDHNQFLGSNILAIAAEKSGIITTPGTPCIVDDTSDYHVLDVIAHKAQEMQAPLHLISDDTTLTSLLRRECPKHKFAPHEVTNLTCALLAFSKVFPKAFAMDDIPELLPKLARTRMPGRLQRLDISHRLSKRKAPILLDGAHNMAGVEALSTYVAHGLRNDEPVTWVVSLSSPRDEEALDLIRALVQDRDSIVFTEYGSRSTELERESRPPAISAKALETRCERRILPEDRIHSEPDVTKALQLAANISQNGPLVVTGSLYLGSEILNWHKESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YD69</accession>
    <name>A0ABR3YD69_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Seryl-tRNA(Ser) synthetase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SES1_2</name>
        <name evidence="3" type="ORF">Cpir12675_006871</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000400">
        <property type="protein sequence ID" value="KAL1886064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11778">
        <property type="entry name" value="SERYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class II (G/ P/ S/T)" evidence="2">
        <location>
            <begin position="2"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00034892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1886064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="103" mass="11674" checksum="4AF272292DE0CC6B" modified="2025-10-08" version="1" fragment="single">HQGEYRELVSCSNCLDYQSRELDIRFGAKTQTDVRIKYVHCLNSTLTATTRTLSCIIENNQTPEGINIPEPLRKYIPGAPAFIPYEKELAPEPVAKALPNRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFI6</accession>
    <name>A0ABR3YFI6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Hexadecenal dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">HFD1</name>
        <name evidence="6" type="ORF">Cpir12675_006727</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000360">
        <property type="protein sequence ID" value="KAL1887046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012394">
        <property type="entry name" value="Aldehyde_DH_NAD(P)"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570:SF11">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036492">
        <property type="entry name" value="ALDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="5">
        <location>
            <begin position="25"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="528" mass="57932" checksum="7764C7BC45132CAC" modified="2025-10-08" version="1" fragment="single">MAPKLPPSPPVPTGLLTYTPTAIDEIPSTVASVRQAYNTLKTHNVDFRITQLRKLYWAIEDYSDLLTKALCQDLRMSSYEADLLEINIVKGLILDTLSQIHSHVADEKVPNLPFTTLPTRVRIRKEPLGVALIISPYNFPIQLSLSPAISAIAAGCAFVLKPSESCSATSAVLTHMITSRLDPDVYSVVNGEVAETTALLDKKWDKIFYTGGNAVAKIICKKAAETLTPVGLELGGLNPAFITPSANVAMAARRLMWPKLMNCGQVCVSQNYALVDRKLVPEFIAALKKEYDIMFPQGAKQSPDLSRIINAHQFARIKGYLDQTRGKVVMGGDTDETELFIEPTVVLVEDEEDILIQNETFGPVWSILPVDSTDEAIAIANRVCPTALAIYPFGDSKETDKILSRVTSGGATVNDGFLHGTIEPLPFGGVGQSGMGALHGRAGFDEFTHRRTVMINPMWTDALFRVRYMPYELKYLKQFRSISPKPDFGRDNQDLRGILYWIKLVLGLGRGSSTSGFLVRLTLAAAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFK7</accession>
    <name>A0ABR3YFK7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1279 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006858</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000396">
        <property type="protein sequence ID" value="KAL1886919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018811">
        <property type="entry name" value="MRX11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28002">
        <property type="entry name" value="MIOREX COMPLEX COMPONENT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28002:SF1">
        <property type="entry name" value="MIOREX COMPLEX COMPONENT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10306">
        <property type="entry name" value="FLILHELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1886919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="220" mass="23724" checksum="3CB62D1D5573028C" modified="2025-10-08" version="1">MPLTSSPALRLARFRINGGGLRYSSSTPRSPSTSTSSTPTAASTTTASTASTSTPVPRWKRIPFVASMSSQPVTSTISFLVLHELTAVVPLVGITACLQYTDPVPLDSLNKYLLDAFSQGLDKFGQYFAKKRWFGFELDAEGKVVGGLTWEEGDRAADGLSEEAKARYKLLSNVALAYALTKLLLPVRIYVSALATPWFANIMKKVGSLCKLGKKNSPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFY5</accession>
    <name>A0ABR3YFY5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cys-Gly metallodipeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">DUG1</name>
        <name evidence="7" type="ORF">Cpir12675_006637</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000339">
        <property type="protein sequence ID" value="KAL1887221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05676">
        <property type="entry name" value="M20_dipept_like_CNDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017153">
        <property type="entry name" value="CNDP/DUG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051458">
        <property type="entry name" value="Cyt/Met_Dipeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43270">
        <property type="entry name" value="BETA-ALA-HIS DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43270:SF4">
        <property type="entry name" value="CARNOSINE DIPEPTIDASE 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037242">
        <property type="entry name" value="CNDP_dipeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="6">
        <location>
            <begin position="214"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1887221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="476" mass="52431" checksum="E40E2674600886B8" modified="2025-10-08" version="1">MAPQLDGFFKQVDDSTDHFIERLRKAVAIPSISAEEARRPDVVRMGQFLADELKALGVTVELRELGEQPGKPGLQLPPCVLGRYGNDKNKRTILVYGHYDVQPAEMSDGWATEPFDLTVDEKGRMFGRGSTDDKGPVLGWLNAIEAHQKAGIEFPVNLLMCFEGMEEYGSEGLDDLINAEAKKWFADADAICISDNYWLGTKKPCLTYGLRGCNYYSIEVSGPGADLHSGVFGGTAQEPMTDLTKIMGELASNDGKIKIPGIMEQVAPVTPEEESLYDGISFTMDNIYESLGSKTTVHDDKKSTLMARWRYPSVSLHGIEGAFSAPGAKTVIPAKVIGKFSIRTVPNMEIDKTNELVCKFVEEHFAALKSKNTLKVYPQHCGNWWVASPKHWNFSAAAKAVERVWGVEPDFTREGGSIPVTLTFEQATGKNVLLLPMGSSTDGAHSINEKLDKRNYIEGIKLLGAYLHYVAEEPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG23</accession>
    <name>A0ABR3YG23_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Alternative oxidase</fullName>
            <ecNumber evidence="13">1.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">AOX1</name>
        <name evidence="16" type="ORF">Cpir12675_006853</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes cyanide-resistant oxygen consumption. May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="13">Binds 2 iron ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the alternative oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="13"/>
    <dbReference type="EMBL" id="JAWDJO010000394">
        <property type="protein sequence ID" value="KAL1886920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01053">
        <property type="entry name" value="AOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.140">
        <property type="entry name" value="Alternative oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002680">
        <property type="entry name" value="AOX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038659">
        <property type="entry name" value="AOX_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31803">
        <property type="entry name" value="ALTERNATIVE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31803:SF3">
        <property type="entry name" value="ALTERNATIVE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01786">
        <property type="entry name" value="AOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005229">
        <property type="entry name" value="AOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10 13" id="KW-0408">Iron</keyword>
    <keyword evidence="11 13 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5 13 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="309"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="309"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1886920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="347" mass="39755" checksum="9361CFC3A448237B" modified="2025-10-08" version="1">MSYSKLGGRFCSVHVKQSLPRRLTANSYYTKLASPYACQGGLRRGFACTAASHMRDFFPAQETKAIRTTPPAWPHHGYTYDEMHKVVPGHRKPRTAGDWAAWKFVRFCRWGMDAVTGMSKAQKAQANVPAGQVVTVKPLTEAQWLIRFIFLESIAGVPGMVAGMLRHLGSIRRLRRDNGWIETLLEESYNERMHLLTFLKMCEPGRFMKLMIIAAQGIFFNGMFLLYLMSPRICHRFVGYLEEEAVHTYSWCIQEIEAGHLPKWTDENFHIPDIAVSYWNIPEGHRTMKDLIYYIRADEATHRGVNHTLGNLEQSTDPNPFASVYKSDHNKPNPTLKPTGYERNDVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHA3</accession>
    <name>A0ABR3YHA3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">UFD2</name>
        <name evidence="14" type="ORF">Cpir12675_006681</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ubiquitin conjugation factor E4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000349">
        <property type="protein sequence ID" value="KAL1887141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019474">
        <property type="entry name" value="Ub_conjug_fac_E4_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045132">
        <property type="entry name" value="UBE4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13931:SF2">
        <property type="entry name" value="UBIQUITIN CONJUGATION FACTOR E4 B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13931">
        <property type="entry name" value="UBIQUITINATION FACTOR E4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10408">
        <property type="entry name" value="Ufd2P_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0697">Rotamase</keyword>
    <keyword evidence="7 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="U-box" evidence="13">
        <location>
            <begin position="1013"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="547"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="72"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1887141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1114" mass="125639" checksum="544ED9A967F3AA35" modified="2025-10-08" version="1">MDPNSNPFEGSSDPGTSQPNQTLDAPDRETMEKIRLRRLAKLGTTTKATDPSESNSGSNPPSTSAKPTKPSRSQLVSPSASSSILKAAAENKTAKPATGRLGIKRHREDHGIDSSSSEKPIAPPARRAMPVQLESLQDYTDRILQTILQVTVDPENHTLKSNKNVQLAFLPNLSAELASENQPLKLNTSILDSAILEATSIFPQNKPLLHYLLPAWSRAQTLRRTPTRDMTPEKTEVLDEAQRMCISNCMFALAMPMLFGRDSDEDDKLPAQYLAHSLILNPTDSCGIDDEFIKEAIARFDEVEGLSDVFAEALRVLSLQVAGMTMESDYRGHFNALLLYSKFPDLLRIVAEHPAFLGAENAPDIQTNTILGPFFNLSPLRTASVKIFFPSPRTMDKAAIARSQDSMRMTLQALQIDLLGIINAFVRVDSKTRGKTLDWFALVVNKNHKRRAMQYKPEEVSSDSLMVNATRILDFLCEPFMDTSFNKMDKINADYFRQNPRVAISDETKINADEATSNEYYAQTIPGSSHFISEVFFLALAAHHYGIESVSSKLKNMDREIKYFEKNLAKMEAERPKFANNPAQRAHFESVIARHRDFIDIMTGKKHSIEGIMMDQKMQETSLRFMRYVAVWLLRVGSQSDYIPGRTITLPLPQTENSAFSCLPEYALQNVVDNFKFVYRYVPQILSFSTGPELMVLCITFLQCSELIKNPYLKSSLVTLLFSGTWPISQYQGGVMTDLLASSDFANKHLLHALIKFYIECENTGVSSQFYDKFNIRYEIFQVIKTVWSRNEVYSKQLKHESKVNREFFVQFVNLLLNDTTYVLDEAMGKFPRIRALEKELASDVPNTLSQEDRQKKDDELQQLASSATSYMQLANETLEMMKLFTSALKDAFIMPEIVYRLASMMNYNLETLAGPKGGQLKVTNPEKYHFRPIQLLSDFIDIYINLGSSPDFIEAVAADGRSYKPLIFDRAYTILSNKSMKDPAELKLFAQIKDRFFEAKAEADQAELDLGDIPPEFEDPILGDLMKDPVLLPSQNIVDRSTIVQHLLSDAKDPFTRQPMTIDDVIPDSDLKYRIAKWKEEKLAAAKQRLKDMAALEVADELAPGPDAMDTTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHL6</accession>
    <name>A0ABR3YHL6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Crh-like protein</fullName>
            <ecNumber evidence="14">3.2.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">UTR2</name>
        <name evidence="18" type="ORF">Cpir12675_006399</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the glycosyl hydrolase 16 family. CRH1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.-.-" evidence="14"/>
    <dbReference type="EMBL" id="JAWDJO010000294">
        <property type="protein sequence ID" value="KAL1887826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017168">
        <property type="entry name" value="CHR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF22">
        <property type="entry name" value="GLYCOSIDASE CRH2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037299">
        <property type="entry name" value="Glycosidase_CRH1_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11 18" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="7 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 16" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046774208" description="Crh-like protein" evidence="16">
        <location>
            <begin position="23"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="17">
        <location>
            <begin position="13"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="347"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="380"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR037299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1887826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="460" mass="48728" checksum="57558E07729D1DFD" modified="2025-10-08" version="1">MYRSTLLGVAAALLWQSSPSSAADQVECSLETKCPESAPCCSQYGACGTGAFCLGGCDPRMSFSLDSCVPGPVCESKTYKWDDPDRIVSTSKYLGDPSKADWVYQGNPMEHNGNILLTMPKNSVGTVMATSAYMWYGNVKAKFKTSRGAGVVTAFILMSDVKDEIDYEFIGVDLSTAQTNYYFQGIPDYNNGGNMSDISNTFDEFHEYEIRWTPDQIDWLVDGRVGRSKKRADTWNATAQQWDFPQTPARVQLSLWPGGLATNGKGTIDWAGGEIDWNGEDIQKHGYYYATFSEVTVECYDAPTAPGSNKKTSYYYSDISATNNTVVDSDKKTILSSFIATGTNMTAGAKKETDSDDESNDSNQVPGGSNVPVTVPGEDSSSSDPGSSSSLGSSSGSSSSSGSLGGTGCGKSGFSQDCDSSNAATISSSATTSAAAASSVALLRGSLGLCILWVGALCAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI98</accession>
    <name>A0ABR3YI98_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006335</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000284">
        <property type="protein sequence ID" value="KAL1888001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019384">
        <property type="entry name" value="FHIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21705:SF11">
        <property type="entry name" value="FHIP FAMILY PROTEIN CG3558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21705">
        <property type="entry name" value="RAI16 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10257">
        <property type="entry name" value="RAI16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="209"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="706"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="865"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="958"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="50"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="209"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="874"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="917"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1002"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1022"/>
            <end position="1045"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1092" mass="120659" checksum="BC42FA85FFD44FA9" modified="2025-10-08" version="1">MDFWSRLLASAGVPAGKSRKDAAKDPAKRLHRFEKEYGQLLHLWRVSGNLSIDEDAIENVELRLQQLTETLSDETRRPLPHPCIQFAALKKIYVPISKIASSSGHEWIVNETVLFFATLIESEEENFVENLDFSNSLTALLTRITKERNNGSRLSPETEERVVELAFNITTKLRLSPEILPAWFRGGMCEDQQQSTSQQLLQVNAQITPSPTGHTRNISSSHTSTGQGVNAETGSGSGGSLGRFTGRTQKQDFPLFYILIDYIHHEGKIGDFARTGLLYIIEASANATTLEQWIVESDLSTLMATGLGAQYSQLSRKLVVDYVPDNLPPVLAFSDYQHPPRTYEIESSCSAQFQAHLDAFLSHLLFWQDVLNHCKSNEIKSTLLEHFQVIFLQQLLYPSLLESSDIDGGSSVAVLTYLRRILESLDHPDMINLILHYLLDLPGPSSPGDALEADKYGERYDGEIENDSNDIEDGEDNMISAARKRKSMDLATMLARTKPDISSGPLLFNLVDLILACLRSHSQQTILVTLQLISTIIKRHHRYGVITLLRTESTPGESSRRTMGAHSQEVEYLMSLASVIGGEDNFEQIYESVVKDTTTKVEGHLCSLKLVSPNATTSNHGLPTIADSLPGAPREVRSHTLRPDDPLLNAALDHLETFLLNPVDMNLSLTETLTDLATCGFMNLEGWLLRHPHKYMFDENLETPLGANTGEDYEDEDSTAESLASCLPPAPDSPSFAEYQRKQQLIACRRRPRWESLPRMLVILDHLCKQVSAYREIIPRFNELLQQRREAFQMADSGMAFPPRRMREPPTPNYEMLQAPSLFTRSASQSRAASPVRGLESLANTSPVRGLENFANKIFAELGVPELGSPPRRQSTSQAQPVVQSQPQSQMRLPIRDRKEALSPSLFPIDTRTVNLSPSGPSASGSAMGESRHDSPVASQVAVFAAMDQSILARKVGAQGGLRESMRPTGLTSKADAKEERSNLGDGPVGSKEVDGDEGQEEQQRDTRAEEPLAGDKEAEPEAGAAAGSQDGSGASQTISSQSSVRDSEPAPEIEVTVSHILTNVVILQAFLFELSALVQVRAGLFNEVRFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIF6</accession>
    <name>A0ABR3YIF6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">EXPERA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_006496</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000310">
        <property type="protein sequence ID" value="KAL1887561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007905">
        <property type="entry name" value="EBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033118">
        <property type="entry name" value="EXPERA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14207:SF1">
        <property type="entry name" value="EMOPAMIL-BINDING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14207">
        <property type="entry name" value="STEROL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05241">
        <property type="entry name" value="EBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51751">
        <property type="entry name" value="EXPERA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="EXPERA" evidence="8">
        <location>
            <begin position="41"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1887561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="253" mass="28145" checksum="BD80BB6D31D39A74" modified="2025-10-08" version="1">MALPPDLFDTTTIYSLASTLAIVFVGIGLGKALLPATASGTTRSLFVWHAVDVLIHLILEGSFLYQAFFSWMPEAEFLAQRGVESLDQLGGNDVTGRNWIYSPMPENYLGTTGRIYGAQAGGNNPFALLWMVYSRADRRWAGADLDVISLELLTVGFDTLMGILVCVALMRGDHKANVWMVILATAELYGGWMTFCPEWLTGSLNLDTSNFMYFWVYLVLFNTIWVWIPLYTLYYSIGNISAAFKALDAKKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIH4</accession>
    <name>A0ABR3YIH4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006277</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000276">
        <property type="protein sequence ID" value="KAL1888126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="151" mass="16610" checksum="DEAA00B3F755FB86" modified="2025-10-08" version="1" fragment="single">MEDFDMADQTRQPRKAAQPHPPEPHNQPPTTRPPTTNAPDHPRKETHPLAPSLNTQSQTRLSAAETAGTPHGTTTIEPAPTAKQTSKTKGSFSKLLDTVWEEACREREAKKRGVAALMLALDQFEANPGLSKEEKTARLEADSLLKEVKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIL7</accession>
    <name>A0ABR3YIL7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_006265</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000274">
        <property type="protein sequence ID" value="KAL1888171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14008">
        <property type="entry name" value="STKc_LKB1_CaMKK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895">
        <property type="entry name" value="CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895:SF150">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE STK11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="120"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="70"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="520"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="540"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1888171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="648" mass="73009" checksum="F93DC64BA7FA9A14" modified="2025-10-08" version="1">MYISTTPESTSHDAVPGQDVVEKLKTSPGLLPAFVPQPWVLRSETSQSLCASIDPQRANASYHKRTLSEYSMLSPGPGTPSGYHSPMRHHRRTPSMRTTVKETLNARSENCLLYHRVNQYRLGREIGHGSYGEVRVGTDSEGHQYAVKEFSKSRMRRRVQSQLLRARGPCRLAGPGTRPGSRLNRPPLSPRVSVMDLDVPDAGDPLSLIRQEVAVMKKLHHENLVQLIEVLDDPEEDSLYMVLEMCQRGVVQSFDEDKRAKPLDEEKARHYFRDLILGIEYLHSQCIIHRDIKPENLLLSEDDVLKISDFGVSQMFADVRNEDMKISQDAGSPAFMAPELCRPKHGDVAGKAVDIWAMGVTLYCFRYGKIPFEEGDDPFEMYDNIRTKRHVLPKDESPEFVGLMDRILDKDPLTRIKMPELREHPWVTMSGIDPLLPEEENCAEFIDIPNELELSQALTRRTTNIFTVMKVLSKLKSRVAKRKALKSKSLQEPLSPVTQANLSESNAQLAAELARRRQHYKANKKRPSFLNLPVEDNLASPGSSSPHSDGPGPPVPFTRYLGIGTGSQYHVPKNNEDNDYVAESPTSINFSFSDLEGTHQYKSQVISESPNHTNTSSDWEDRGLCEHTMALRVDSGYGEISEALKKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ70</accession>
    <name>A0ABR3YJ70_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000316">
        <property type="protein sequence ID" value="KAL1887479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="76" mass="7748" checksum="87B2511B2CF093E6" modified="2025-10-08" version="1">MPGSAASSGATSPIESSSINALTNQVEKGKVKFLIQTGGKKYHCVLKDRVAHERQKAALSTASSSAASVNSGESSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ80</accession>
    <name>A0ABR3YJ80_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Cysteine proteinase 1, mitochondrial</fullName>
            <ecNumber evidence="2 9">3.4.22.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">LAP3</name>
        <name evidence="11" type="ORF">Cpir12675_006250</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin. Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity.</text>
    </comment>
    <comment type="function">
        <text evidence="7">The normal physiological role of the enzyme is unknown, but it is not essential for the viability of yeast cells. Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin. Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity. Acts as a repressor in the GAL4 regulatory system, but this does not require either the peptidase or nucleic acid-binding activities.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a carboxyamide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred.</text>
            <dbReference type="EC" id="3.4.22.40"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homohexamer. Binds to nucleic acids. Binds single-stranded DNA and RNA with higher affinity than double-stranded DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peptidase C1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.22.40" evidence="2 9"/>
    <dbReference type="EMBL" id="JAWDJO010000271">
        <property type="protein sequence ID" value="KAL1888243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00585">
        <property type="entry name" value="Peptidase_C1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004134">
        <property type="entry name" value="Peptidase_C1B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10363">
        <property type="entry name" value="BLEOMYCIN HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10363:SF2">
        <property type="entry name" value="BLEOMYCIN HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03051">
        <property type="entry name" value="Peptidase_C1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005700">
        <property type="entry name" value="PepC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 9" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0788">Thiol protease</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR005700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1888243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="518" mass="57514" checksum="A3E1E4DE734963E7" modified="2025-10-08" version="1">MGNQQSILERVADEKRASAGSGSSASEDDDYVHVDTVNEKQPRDLADLRTRTPEGLWVHRLVDEQSKILAQPKNRLALAALSSANPRSVLKSATTKVNDQHIFNTAIPFEGAPITNQRSSGRCWLFASTNTFRVALMQRHRLAEFELSQSYLFFWDKLEKSNWFLEQIIDTAVEPLDGRLVQHLLGDIVSDGGQWDMVYNLVDKYGLVPQVLYPDSFNAKATGVLNSILKTKLREYAVQLRALCSSAETGARGSAIGKADLARLRSAKTAMMHEVQTILTLTLGAPPDPQEPFTWQFRDRDGKAQQLTTTPAAFARDIYSADFRVSATGIASMLSLVHDPRHEPLTKLTVPRLGNVVGGRAIGYINVDMTILKNACVAMLRAGMPVFFGSDVGKFSDSGAGIMDLNLYDYELGFNVGLLDGTDKATRLRTGESQMTHAMVLTAVHIDHEKGAYVRWRVQNSWGADVGDKGWFVMSDAWMDEFVYQAVVDPRFVPKEVRDVMSKKQIELPIWDPMGSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKE9</accession>
    <name>A0ABR3YKE9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006213</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000265">
        <property type="protein sequence ID" value="KAL1888357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039467">
        <property type="entry name" value="TFIIIB_B''_Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22929">
        <property type="entry name" value="RNA POLYMERASE III TRANSCRIPTION INITIATION FACTOR B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22929:SF0">
        <property type="entry name" value="TRANSCRIPTION FACTOR TFIIIB COMPONENT B'' HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15963">
        <property type="entry name" value="Myb_DNA-bind_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="585"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="467"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="683"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="169"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="273"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="498"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="683"/>
            <end position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="740" mass="78600" checksum="47DDD66CB8AFACD9" modified="2025-10-08" version="1">MSSMFKKRTGGPAFKPKIGPRGPRAPAGAAAPSTTASAAAVVSPPATQPSTRPDPSSGSGPSVSPTPPPSSDRHATPSALALAEKLQALSTPSESSIPHTESREPLGDRQAERQSSQTPSQSQPQSSPGSESQPQPSPAPRPRIRPRLLAKAGASTTTNNPISGITRSAANNTANTTATTTPLAVTPHLPSSPSQTSDAPLKSQDIPAQASPHTHTRTSTSTLPLNNSPPTAAPIAPYAPIALTSASADSISHNNPILLPTPEPSQQQPPPSSTSAPSRAFSPEPSSSSSPLFHGQPVPSIDSLPELQTTVSTPTATDDSQLTPADSTNVSIAGSDAGGAVASTAPAITRKRKISTPDQTSHDVAGPSSKRSRKPRATIEVDDDVTTTSPATPLPPDAVANGDPPAATAHLRRRRTAASAIGSGRRRRARSQTPPNSENQMVDLQKLTMADLTRDLRIGKKFSRHEELKLRERHARSKSMREPTPDGNSNDKDDSENPAPGAGPSTTSSSSAATSKDKSSSGDTDPTGPKFFIVDGQIVLDQGSLVVDRHAHAAVERKGMKVVEEHDFSRLVTSNSFRTGSKLRGPNHWTMEDTEKFYHALKMFGTDFQMISNMFPGRTRRHVKMKFNREERLAPTRINAALVGEKHVKMDIAEYKASTGIEYESVEAIQAEQQALAAEHEAEERRMVEDQESEMRRRREELFRDDEKPPVDENGITTIVDSGEGPVYFGAGPSTKGSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKQ6</accession>
    <name>A0ABR3YKQ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA-directed RNA polymerase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_006177</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000262">
        <property type="protein sequence ID" value="KAL1888418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.120">
        <property type="entry name" value="RNA polymerase Rpb7-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036898">
        <property type="entry name" value="RNA_pol_Rpb7-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041178">
        <property type="entry name" value="RPA43_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045113">
        <property type="entry name" value="Rpb7-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709:SF5">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II, III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17875">
        <property type="entry name" value="RPA43_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RPA43 OB" evidence="7">
        <location>
            <begin position="274"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="45"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="108"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU369086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="458" mass="50099" checksum="ECAE20CBBD3D21FC" modified="2025-10-08" version="1">MSKSSEKKRPRDEEADAAAAASKKQKVKSHDSSKKKSKKGEKIEAAAQAEPVAAAAVAEPTDKAEKKYRKSKKAANVQTQAETPSDTSSSEEEEDFKEATTKSGADDSSSDEDSSETDDSSSDSGDDKKPAITATTTSTPSTTTSTASTSTADRPLQSIETKPPGNGYFKPEFAPKQLEFPLYTQTFSIKTSLFPVGFDKPAAAAGTQLLAPMLNRYSSLYHGVLLAYRNVIVSQWPSRIGASETNAQPVKLQSRDEFAVGFAWVTADMDLFVPSVGAWMEGEVVLQTEGHIGVVCWGRFNASIEASRLPRTWRWVAAEEAEFEDDSMELENGASEDAAALTPQTTGYWADEKGTPVDGKAVFRIKRFDVGVRDDHSFISIEGSMLDDKTEAQARTGELQREENRRAKSSGYLMGSRKRVIDFSVTDCGVQEEEIRDIRSQIDWRRARPPTPTSYSMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM60</accession>
    <name>A0ABR3YM60_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000239">
        <property type="protein sequence ID" value="KAL1888922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="176" mass="18755" checksum="7A4782867A091C69" modified="2025-10-08" version="1">MCTHIRRDLACGHCKFLIHMFCANNRKNGRRCRRFVIHREYWGNTICRECQSQTAPTRYDAAGFKMPYPVKKRPSAAISTVRKGRSVAAATAAAAGPTATTVSKSTSPTPSLVLALAGSSGPPSGSSSEFASNATRPSSGNNPSPDLYDTYDVSGSKTVVKSAGMTMQQPLPQIGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMB8</accession>
    <name>A0ABR3YMB8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Vacuolar morphogenesis protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">VAM6</name>
        <name evidence="6" type="ORF">Cpir12675_005963</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the VAM6/VPS39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000235">
        <property type="protein sequence ID" value="KAL1888990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001180">
        <property type="entry name" value="CNH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032914">
        <property type="entry name" value="Vam6/VPS39/TRAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019452">
        <property type="entry name" value="VPS39/TGF_beta_rcpt-assoc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019453">
        <property type="entry name" value="VPS39/TGFA1_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894">
        <property type="entry name" value="CNH DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894:SF49">
        <property type="entry name" value="VAM6_VPS39-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00780">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10366">
        <property type="entry name" value="Vps39_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10367">
        <property type="entry name" value="zf-Vps39_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50219">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CNH" evidence="5">
        <location>
            <begin position="18"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="460"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="907"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="465"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="486"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="534"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1888990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1101" mass="121196" checksum="C3DEA2F574F18987" modified="2025-10-08" version="1">MLSAFTARPIIELRQKDKSKIESVLAFGDRVLVGLNTGVLRIYRVNELPSEQKPQPLALTDDVINNGANAVSDVSEPSLPKYKATDLLREVEKFSTKPIEKLAIIKEANTLVSLSNYQVSLHDLQTYKLVQSLQGTKNATCFATTSNIVKDADTGIPEIISRLAVGVKRRLLLWTWHESELNSNVNEIILPESIRTITWANASTLVVGMNSSYSIVDVISQSIEEVSNPGTANGSNGGPSRFGAMGTASISYMGLGSYMPKPLSAKLGEGEIFLAKDVHTLFINDKGQPLRKRQITWQAAPESVGYSYPYLLALQPPAKGSLEIRNPDTLSLLQIMSLPGAAQLHFPPPTVSLAHAGKGFHISSERCVWTMDATDYDSQIAELIALKEYDEAVSILNMLEDALLQDKDGSLREAKMRKAEVLFREKKYRDALDLFNEDDVHAPPERVLKLFPPSIVGRYSGWPDLQEDESEQEDGQAEEVEKRPTESSNGANGVNQPLASGLTSSTAPVLTGDSRPSTPQNNSAGGFVRKIMGQNKSSDTASIAPSLATSEGSDNVNGNTKPNKPAKVQKGGDYQLDTKDLTNAVLELNSYLAGTRARLQRVIDPGTGKLKPREKGTAAEQTMKRLLTSIQGDSDLELEKQLCETFALVDTTLFRAYMFSRPSLAGSLFRIPNFCDPEVVNEKLLEHSRYNELVDFFYGKKLHAQALALLEKFGRSQEPNPAAPSLHGPSRTIRYISGLSPAHIDLILEYSEWVLKAALKEGMEIFVGDTENAETLPRHRVVQFLGRIEPILEIQYLEHIITELNDLTPDFHNRLSELFIEHLKGTPRDNEWEAVMGRFVKFLKDSRQYSLSRAFSMIPRDEPAFYEAQASVLSLMGNHKQALEIYAFKMEDYSKAEEYCNQVHVAQNSTPPVSRPASSDGTTGDSKPSIYHTLLSLYVNPPNPYQRKLPPALDLLSRHGSRLPAESTLSLIPNSLAVCDLEAYFRGRIRASISQVNESRIISGLRAAEYIGSQSRLLLGDDLPASAGVAGRNRRIVVTDEKLCGVCHKRLGGSVVSVLPDNSVVHYGCLGRSHSNTGNGLVGISKPDSVRASEWGRRSIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMG0</accession>
    <name>A0ABR3YMG0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="21">Actin cytoskeleton-regulatory complex protein PAN1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Cpir12675_005765</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the PAN1 actin cytoskeleton-regulatory complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Actin patch</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PAN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000214">
        <property type="protein sequence ID" value="KAL1889524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00052">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216:SF173">
        <property type="entry name" value="ACTIN CYTOSKELETON-REGULATORY COMPLEX PROTEIN PAN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216">
        <property type="entry name" value="EH DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12763">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00027">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50031">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="10" id="KW-0967">Endosome</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EH" evidence="17">
        <location>
            <begin position="230"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="18">
        <location>
            <begin position="263"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="17">
        <location>
            <begin position="491"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="18">
        <location>
            <begin position="524"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="616"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="723"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="920"/>
            <end position="1387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="9"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="85"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="124"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="162"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="632"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="723"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="920"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="937"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="957"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1010"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1092"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1127"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="1159"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="1184"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1200"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1234"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="1245"/>
            <end position="1257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1258"/>
            <end position="1271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="1275"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="1367"/>
            <end position="1387"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="19">
        <location>
            <position position="1405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00025194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1889524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="21">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1405" mass="152224" checksum="FA413DCD25DEE216" modified="2025-10-08" version="1" fragment="single">MYSNPTGFGQQQQQQQQQQPQYGAAYGQQQPPMMGQQQQQPQPFAPQPTGFGQPAPLQNQYTGFPMAGQQQQQPQPLMGQATGLQSQQSAFQPQQTGFQPQNTGFQPQQQLFQQSAMPLMPSIPAQYQQQYQQQQPQQSQFQQPPQQQQQPAPSLQLPQATGFPSVTPPQQTSSAPSLIPPPPAPPQKSQATGFAQMAASFQTSKPQTPAAPSKPNSVPNIRLSFITASDQARFENLFSKSVGDGNTTMTGEKARDLLLRSRLDGDSLSQIWTLADTTRSGQLHFPEFALAMYLCNLKLTGKALPPVLPDTIKNEVSSMVDIINFSIAEQVAASGRATPLPAPQPQPSNSQLLQTQMTGFPGTQQIPQIQQSQPTGFQPQPTGFQSQQTGIQTQATGYNTQGAGYNGPRPPMPPMPSSFSSGLAPIAAPLNAQPTGRPGQWGLVNTPATGLPNIDALAARMMPQNDRASGSFTTSGLQGNAVIPWAITKDEKIRYDSLFNIWDGLNKGFIGGSQAREIFEQSGLEKPDLERIWTLADSANKGRLDMDEFAIAMHLIYRKLNGYPVPSTLPPELVPPSTRNLTKSIGAMKNMLHEESEHRKNSGAALLPQKTGVSYAKNHSFKSGSGVGGNGGRKDATVFKNNDDDVGYRSSARRRANNRSPQPGTTPSNDEELSLDQLRKKVREKQVLLDAMDFKDEKNSEEDDILDRRDRRDADDLYRRIRRIQEDTDSHPDAALSSGDSDAERRALKRQLQKLTDKIPELASAVRRSEKEISEARLELFRIRDAKQYPGSATSIIGTGPGGAITESDRLKARAKAMMQQRTAALTGRKIEGASDDLDAPKRLEEESMKIRYEKENNERMVQDVEDSVREFSRSIEDSLKSEMKDSSSEHERRRWEDALGVEDEVRDFIFDLQRDSRSARLRAQEKRSLRAEPPSRTDSPASRLSNSSPAGLAKTSSPAPSAGGSYSSYETPEQRAAFIKQQAEQRMAERLAALGIKAPTKPGESAAQRIERERAEREAKLRQAEEEDSRREAQRQARLAEEQGVPVPVEPVEEPKQEPKKAPPPPATRKAPVAKPEPASAAAPQDDYDNEREAAESRLRALEEQVRHNKLRKEEEKKKKKAALVETKERESKAAARRAEIEAVRKREEELQRQLASMDDDSDSSDDSEDPGYTGSQGLDAPTPAPAPAPVSVSPPPSSSSSVPSAAAATSPPAAATSETESKNPFFRMMSQSSSSTPTTAPAVPAPAPPAPPAAPAAPAAATSAADASTNPFFRPPPVSSTPVPAAPAAPIMPTLSISRDNQDDSDDDGWGSNNENSDDESDDGRPGGNSAAHLASLLFSTMAPPRPLSAADEKPTSSSPVSSSPFPPPIASSAPPAPIAAPPVEAPEIAETPVAPVLISVPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNP2</accession>
    <name>A0ABR3YNP2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005582</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000199">
        <property type="protein sequence ID" value="KAL1889936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="190" mass="19784" checksum="C2DB8E6934910448" modified="2025-10-08" version="1">MGSSDNVNVPAAAGSYSAATIDTDLRTSINMTLLRDGHVNKIQEHLLQSLNSNSADWPTLVQNHALTLLRNGEASSFPDLLRRVLDDVRAANSPASLAALATADPGSPSATTNGSSSTRDKDKEKEKDTDSIHGSSESTNGDGLARNGGSNSAAPANGNFEAGLALPRAVVQSALRVTRDCLEDVVTVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP66</accession>
    <name>A0ABR3YP66_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphatidylinositol-specific phospholipase C X domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_005554</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000196">
        <property type="protein sequence ID" value="KAL1890028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051057">
        <property type="entry name" value="PI-PLC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593:SF113">
        <property type="entry name" value="SI:DKEY-266F7.9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047485115" description="Phosphatidylinositol-specific phospholipase C X domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidylinositol-specific phospholipase C X" evidence="3">
        <location>
            <begin position="45"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="347"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="416" mass="44771" checksum="7EA309417C716201" modified="2025-10-08" version="1">MRFSLLASLASLALSRAASYGAFNDPWSFDLAYGPYNNWMQYIADGTSLASLTIPGTHNSMNTHIGDELLQSQNTPLAYQLTGGVRYIDISCTTIDGNLMVTHGGAQTGFTFDHVLTTIYDFLDANSREAVILRIQKGNSLESTSLFASQIRKSLSPGTALGNRAAQRVFSRGSSSIAAIPTLGEVRGKVFILQDFDTKSGQFGLPWSSRLVSYYHFKFGLRPLLAAKWIAVQTYLTVSLNSPEKLYVTDVTVSVGSKPITFAAGPHDNPGINARLGGYLQTAKSSSLGNFFLGNNRGYFGIIVMDFPGKSVVEQILKFNKRYEVIPPGVSVPNYGFPPAPNHGFPTNNGFPPNNGFPPNNGFPPAPNNGFPPAPNNGFPPAPNNGFPPVPNYGAAYAHGAYPAAGNYRDPTNPQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ18</accession>
    <name>A0ABR3YQ18_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_005394</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000183">
        <property type="protein sequence ID" value="KAL1890469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1890469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="699" mass="78138" checksum="5C294343550578F2" modified="2025-10-08" version="1">MLSSLYFAIPIHLTPRGVEAILSKIHELEYSCTPIGNAISGLLARFLKRAGQIRDSELGSDDEDEGLFDNCEFGSLTGLCHQRNGAGDLVPLTETEKQDMHRFALPNDIASMPFTAIWDRLEEASTGVWQWSLRDMLRQYGTVGETLKMLAQETKTTMVPNVQAQVVYIGADSQAAIKEALRKLNILEKDKYPSQSPINIIQPPNAKRYELAFESLDSLGLANSMFFNPGKESIEDVSAQVSTSYRISVIYGGVNDNSLVLRRPVSSEARLDIESIPLRTFSCNEYGTELEDCLGRLAWDDNTSQVKPKKKSLKSMPKKSTIDNVIFEPAAFSAGRLSLDGPESYGTPGLLTPIDALACVQSQELFCTSLLKNAYVTLDRARLWRGEVSLKINFGRFMVRSDSEIFNGIEPLEVEKPVGFRPDDFAMFLNSPDSPSRPIVAFSPIMTTVGQEIQVFEKDIAAFGFKFKSSITCLDFSCVSCDEEFLVSFRADLDFRSSMRFAPSRAELGRINIHCPESLNDMCLTVSVSDPDILRAKYSDFLKFLKSRTLVRVDRSQPSRIAVLYPNLDGASVQISGLAICTTHTYEDSAKSHRVEVRSYQAFSNELVKDNTMVLAKIYHDKTKTATNNGLPKKWHEISLSTNATNEAFKKNRKLALGEYSAWTAEKLDVDEAIDRFIKLGLKMVPVTDHMNHIKWSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQT8</accession>
    <name>A0ABR3YQT8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_005386</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="protein sequence ID" value="KAL1890462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="BAR_DNMBP"/>
        <property type="match status" value="1"/>
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    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AH/BAR_dom_sf"/>
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        <property type="entry name" value="BAR_dom"/>
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        <property type="entry name" value="DBL_dom_sf"/>
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    <dbReference type="InterPro" id="IPR051492">
        <property type="entry name" value="Dynamin-Rho_GEF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22834">
        <property type="entry name" value="NUCLEAR FUSION PROTEIN FUS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22834:SF20">
        <property type="entry name" value="SH3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </evidence>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQX5</accession>
    <name>A0ABR3YQX5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046185395" evidence="2">
        <location>
            <begin position="17"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
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            <begin position="201"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="135"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="265" mass="28183" checksum="C419C316C6100AFF" modified="2025-10-08" version="1">MKASLIILTGASTVSAMWFPNFCCGGFPSADEPQTTTTAATTAATSIPAPTSTELGLDRIYLASSIDREPTTLSTSIIPTKSSDAGSIPIDEDLTFEVNPTANAEITAYTTEVSESINPESVHFSDGEEADDLLGFDSGSDSNSNPVVDPDRELKWIAEETNSKLDATNNRLDSLIQGFKENSARMQALIDKAQKLHAAEGVSGNSEVEDEVHNEEGISFPILPQTTDPNAATPRLGNGYSASSQNFGEDFDDADGSKNTEYQSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRD2</accession>
    <name>A0ABR3YRD2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Thioredoxin reductase</fullName>
            <ecNumber evidence="7">1.8.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TRR1</name>
        <name evidence="10" type="ORF">Cpir12675_005383</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="8">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.9" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000182">
        <property type="protein sequence ID" value="KAL1890489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050097">
        <property type="entry name" value="Ferredoxin-NADP_redctase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008255">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005982">
        <property type="entry name" value="Thioredox_Rdtase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01292">
        <property type="entry name" value="TRX_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48105">
        <property type="entry name" value="THIOREDOXIN REDUCTASE 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00469">
        <property type="entry name" value="PNDRDTASEII"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00573">
        <property type="entry name" value="PYRIDINE_REDOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 7" id="KW-0274">FAD</keyword>
    <keyword evidence="2 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 7" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="9">
        <location>
            <begin position="4"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="317" mass="33827" checksum="B5380763DD29062C" modified="2025-10-08" version="1">MHSKVVIIGSGPAAHTAAIYLARAELKPVLYEGFMANGIAAGGQLTTTTEVENFPGFPEGIDGQSLMDNLRKQSEKFGTEIITDTVTKLDLSSRPFKYSTEFNPTETSTADSIILATGASARRLDLPGEEEYWQNGVSACAVCDGAVPIFRNKPLVVIGGGDSAAEEALFLTKYGSHVTVLVRKDHLRASKTMANRLLSHEKVTVRFNAAGDKILGSNGLMTQLVVKNTTTGETDTMDANGLFYAVGHDPATALVKNQLKLDEDGYIVTQPGTPLTSVEGVFAAGDVQDKRYRQAITSAGSGCQAALDCEKFLSELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRI3</accession>
    <name>A0ABR3YRI3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transcriptional regulatory protein DEP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_005398</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000183">
        <property type="protein sequence ID" value="KAL1890473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013907">
        <property type="entry name" value="Sds3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21964">
        <property type="entry name" value="BREAST CANCER METASTASIS-SUPPRESSOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08598">
        <property type="entry name" value="Sds3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01401">
        <property type="entry name" value="Sds3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="579"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="156"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="174"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="200"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="251"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="593"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="611"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1890473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="648" mass="70612" checksum="4F2D950DDBDA1C9D" modified="2025-10-08" version="1">MATATQPAPGLHLIEPNLDAEASTTTSPLSEVEDKDGLPDGLDNNILASGKPLIADDDSDSNLSDAGNDTEAETERLYDTPMIQRHKSVVIDQFNQDHIIEKTPTRLGRTVKSPPIGSDDLDGSYASDGLPQSPLPNVASKLANQKRKRSPDTEASENGQPNLKRSVSGALSGRESTQVSTLQTLIADPLDNSCQQPSIIDERNSQELKGTDSGIAGLSRDSKPPNGIKSGGASTNSNSHDDMDVGSDDDAQARSDHDHDHDADIDEEAEAAARNEEECKANPHFYDGYRVSVDTNISSVVEKKRIALEEWAAIEARFVTFRDRLFKDRLDKLEKEEQSLLADEPYHPEYLAMKQCIDERYETKIRHIDKEYEYVLKAHEQVAIATRAQIWSQFYQGMREKREEFLELLNKDWYDTQNIRRKAHSVPDVALLYPSTPAQQTRNAIAYNTEVSILSGIAKHVGFPAVPMMLGASELEVEDDLNAIKHVMYQPHNRLSPVTVSTPAPTSVSGQAINAPQAMHDIALHPATIHARDRSQAPIAMPAVSIPTSISDPLETSTDMITAAATATGDSTHVAPTTAIATMPPNRTKASGHRSSNASSRRTGQAKAKDVSTSASHSTVANRSRLSSHVPSNVLPPPLRPSMDATRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRP5</accession>
    <name>A0ABR3YRP5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Calcium/calmodulin-dependent protein kinase type I</fullName>
            <ecNumber evidence="6">2.7.11.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">cmk1</name>
        <name evidence="6" type="ORF">Cpir12675_005328</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.17" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000179">
        <property type="protein sequence ID" value="KAL1890576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004683">
        <property type="term" value="F:calcium/calmodulin-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="20"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1890576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="399" mass="44999" checksum="AC36D6C6D47FB56C" modified="2025-10-08" version="1">MSTEKDEEPAQHPHIQPCRYQVGKTLGAGSYSVVKECFHIETGRNYAVKVINKRLMAGREHMVRNEIEILSRVSMGHQNILTLVDYFESMNNLYLVTDLALGGELFDRICRKGNYDESDASELIRSTLSAVSYLHDHGIVHRDLKPENLLFRTPEDNSDLLIADFGLSRVMDERKFHVLTTTCGTPGYMAPEIFRKSGHGKPVDIWAIGVITYFLLCGYTPFDRDTDFEEMQAILNAEYKFEPAEYWNGVSEGAKDFIQQCLTIDPSKRPTAHEAMQHPFVTGESQQGMQIDDRLHIIRRNFNARRKLHTAIDTIRAINKLREGQSLVMDARKNEAKTRQISDSQPVPEDVEMGGNLDTALTMGSIDVPDILKPGKSANRVVETSKGLWGGAPVNSGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRT0</accession>
    <name>A0ABR3YRT0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sds3-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005142</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000164">
        <property type="protein sequence ID" value="KAL1891016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="520"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="583"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="709"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="933"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="393"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="587"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="960"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1027"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1110"/>
            <end position="1119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1119" mass="121351" checksum="4845C828120A584E" modified="2025-10-08" version="1">MSASDLLVADPQPSPLSNALGPVIVDSLPQASAPLSSSSSSSLSPPATVPASSSILPSMPSTAPVSSTEPFEEAPLTSTAISTPTPTSAPAANANSNSRKAPVVSRSTRAARGRARGGRSRGRGGRQNAASNRTNAGVGQGRKGRGRIKQFGDALVQACYERSREVKDHYNLLVAALRPALGDLAQRNVDKLMAEPHAHELTPEYQKVIEGVNARFAQTINEINVRFHAEQHALYQAMDHQRYVIQEQTKNAIEDVECQFIDAQMNRLRILEKLYDLGLPVDIEDLDHIFKPVTDVEYKNFGPFVDYDEDEHVVPYPSRVPGTEMYKLLQQFTQQYKIEKAAATAAAQEARLQARALAQQEEAESSTKRRGDRTSTMASRRNPRSNARGGRQNATASSNTNNSAPAATATNGYEPAENDEDEPATAKHPMGILGGVGDEAVALESSTAVQEPEAEEEEEIADTTNSELPVRERSPPPATGMQPPDEYGAAIVISRGKGHNRIMLRPPPFEVDDIEIGFRDSSNDPTRGANVAANRGKYTGTPHTGSVHVDPMLWNYDARANKEGDLDEKLVEKHQLHPSFGFFLRTSRNDDPVPEDRPEDVHRGRPVVYLPPGDVIVSACRSTVAMISEKVDDARKGQEIGTAISVYCEAVGIEKEDIVPDSDELIPPEFQGQSLRYPSLRGDRTAMRRLFAEETARAARLAACVKNEQSVSVSDTSGDDARAHQEQPEQPGADMDTQGIESLVQASILASVRDLAEDSSEQRSSYDAIRDVFRPSAPEPPRREIASIAMLTLAAACDTAPRIHEFGTYASLSTGPLASLPLMHQNYASSDAPLLMNGYEMGISKASPDDYPGHNNGMHPQVRYEQPPLMGQQQLPLENYQQQDAVNQYAHMANSDYPQSQQMVGSGSQRSPLPPLRPAVQEHIAIRHDAEQPAVGGFYPPPPPGLASGSHHGYQYPVEHMGSQQQPSHQQQMSMGSASASGNGFYQSQPSPASFSSPSLYESHLGQQKLAPASSRDRSSSVAALPPSSNLAPGSAASSVGKYRKLEPAPVPKHRLGWANDTQPQLRTVGYDPSSDIKDYAANEPLPGRAPTYIRAWSHNGANAPRRNSKKDGERRDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSH3</accession>
    <name>A0ABR3YSH3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Enoyl-CoA delta isomerase 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_005197</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000168">
        <property type="protein sequence ID" value="KAL1890909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF75">
        <property type="entry name" value="ENOYL-COA HYDRATASE_ISOMERASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1890909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="268" mass="29644" checksum="69A6D3FC1EF839EC" modified="2025-10-08" version="1">MAQLFNIKIPALGQYPGGALLVSEPAPTVYLLTISYAPDNRLVAPVCGAMLEALDILEARYPMGVVITTSGIPKFYSNGLDLQHAISTGRDYWVNYLYKLWARIATYPMPTIALLPGHAFAGGLMLAMYHDYRIMNPSRGFTCLNELDFGVPLKPQMSHIFREKLSFSAYRSLALEAKRVPGPEALALGIVDVLGGLNEALELVATRKLTEKGKTGVYGLMKREMNRNLLDMLTPAGYDKEEAREAKLNAEMEKEYNARGLQAPKSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSZ4</accession>
    <name>A0ABR3YSZ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000161">
        <property type="protein sequence ID" value="KAL1891140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="107" mass="11071" checksum="6188427F639E4A59" modified="2025-10-08" version="1">MTLSQLSEKPTADTAVPLPSQTSSMSSIPKEDAIGTMPSTPSSTAHHGATTQTYNVIDPESQSPPPKDKPMFCGIQRRSMIITVGAGLLILIAAIAFGVGAGIAFKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTD1</accession>
    <name>A0ABR3YTD1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004903</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000150">
        <property type="protein sequence ID" value="KAL1891594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF39">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="2">
        <location>
            <begin position="25"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="392" mass="43562" checksum="9DDD3373938CC5A1" modified="2025-10-08" version="1">MAYKTDRHLSLCQAMVHQSSCPDQAYIYIGSAARIAYTLGLHIKKETHARPMFQRQLELRIFCTIYLLDMDIALAHGYPPALSEADAVKDLHLTTEQILCPGSNIPPGYQVVASQLSQLSRRISALLYITPDSGGRTRFLADVMGCVSTLHTWMDDLPLPLRNCKDATQCHGRSIAILHLRYYSTMILATRPFLLHTALGSGESGMEAKRKTFQDLAMLCIDAASQSLDILQHMQANGLISSLASLDATFLMEDIQVFLLVMSANTRRESGLDVSHKAYACLEILQSMEQVQGVKSTLDKALAQLREYSIIDASNGLVRREPTRDQLFLGMESTQTLPLYVNLFDGNPKDTDNSISNPFGVFFCSFPNRYPNAAATMGPGLSDFQLIFEELH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTY2</accession>
    <name>A0ABR3YTY2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycosyltransferase family 28 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004839</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000147">
        <property type="protein sequence ID" value="KAL1891766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF13">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyltransferase family 28 N-terminal" evidence="2">
        <location>
            <begin position="135"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="294" mass="32172" checksum="82A4B20DC549094F" modified="2025-10-08" version="1">MGSKKEIEAMGYNQPSADPRTNDSDDDTATVSSESAAPFQSYRPYSTLSMAPNDESPPAYAEININNDAFSGAANITDDGRINVNINRASNFFAHFMSPAPNVNPQNDPSDQPPAYIPEGLGFTSHNLPPPRLNIVIQIVGSRGDVQPFVALGKVLKNTFNHRVRIATHGTFQNFVEENGLEFFCIGGDPTELMAFMVKNPGLIPKRDTLRSGEISRRRKGIQEMVEGCWRSCFEPGNGTGEALRPHKKGESLEEGFELSGQPFVADVIIANPPSFAHIHIAEKLGIPLHMMFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU47</accession>
    <name>A0ABR3YU47_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Increased rDNA silencing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">IRS4</name>
        <name evidence="3" type="ORF">Cpir12675_004768</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000143">
        <property type="protein sequence ID" value="KAL1891909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00052">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12763">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00027">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50031">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EH" evidence="2">
        <location>
            <begin position="585"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="471"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="574"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="167"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="364"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="476"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="697" mass="74960" checksum="4029A8F7CFFC6A65" modified="2025-10-08" version="1">MSNNGAAALKGASLAFSSSAAESRVQSPLPSTKPKPKPKPKPKPKTTTVSGRGAKSASRSSDTSLGNQGKPGSLAALQAANISTGTPTLLPSKTSSAGRSPAYPGLSPPRCSSPSASVMTVASTAGSAAGSAVLPGVRYLYPPGATAQPDPKSPSYIAASLAAHRAVSPGPSPSVVVRQGMATKRGESVGSNSCSSAGRRRPSSMVMQRENASSRVSLSESLSSKEKLLDTSSIGPTTSLIGMFEENKQPETAEWNRTQVKRTPTRHSLMVLPTSPCSSLDGFKYADLQPTRDSKLPAIVAARHVSTSPSPSRPHTPQSTKELLFQAAPAAALKAAVTHRQRASRPPTPPLSRNLSRPRPPSPSGSSRQSSSPEMASLPRTFNHRQTLSVSSIHSSPGPQTRRNYTGSNTHNLNQHGSAMSLNSLTDAMLASALAAKRLTPSSTGTSSAITQHHPATLGGQAASRQKSPHLLPTLRNDHGQHESDENNAERRRKKHTLTKIGAKGKHRHHEGSRKRWREEVTERERKRYEALWASNRGMYLVDSVYPVLEPAAIAASIAGSMLPIPPTGIKVTAPPKGAKGAVDESTPTDSTTEIASDDERDLVANVVVRELWRRSRLPYDELAEVWDLVDRQMRGALNKQEFVVGMWLIDQRLRGRKIPHRVQKSVWDTAKAVWIKPAHRKHHEYRHGNEHRKRRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU98</accession>
    <name>A0ABR3YU98_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_004883</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000149">
        <property type="protein sequence ID" value="KAL1891662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF13">
        <property type="entry name" value="RESPIRATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="80"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="108"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="129"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="502"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="504"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="519"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="530"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="561" mass="59732" checksum="51D3E535F2C96CC8" modified="2025-10-08" version="1">MASQTRDDVFVVAAASGNDPQSVDAPASKTLSVASKSAALATTTTPVSSTSLSATPASAITGLVTKPQFPPPKTDKPRPHVCQTCQRSFARLEHLKRHERSHTKEKPFECPQCRRCFARRDLLLRHQQKLHQTSTPNPRPRNRRDSAATATTTPASGRVRKNSVAGPVTTAAVAAAAIAATAVAESSGNGTRAPRAQPTSRPRANTISHIDNGLQMQQVQNMLQQQMQPPRMPTSHVRHPSLIGLASLHGGHGLDLSFGGITSSLAGHRNIGANLSRIDTNALHDPFDTSSFRTAPPTTFDFEMDDLFFASNNTTNTINPNALHYNDSPQSMPMDPTLSPPLLNNETAEWLENMEPSQEWNNDSSLFTAASSPSVISNGSHGLNDSLPMIPNNDQFLLDNSLHGHIGISTIQSSFNEMAILDTGDQAFSAATAATMWPPTLMNGHMGSLGLDTNFSEFLVGNPMSPAFQPMNFSTTSPNIASPSAPVPYAPPSVFSSAPEAVYNTGSESPSSAATTLHSAVSASSPASSITDTTRDTAASGMTQPQNQQNLDRMYLVLTPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV69</accession>
    <name>A0ABR3YV69_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-binding transcription factor cat8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CAT8</name>
        <name evidence="5" type="ORF">Cpir12675_004641</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000136">
        <property type="protein sequence ID" value="KAL1892173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15485">
        <property type="entry name" value="ZIP_Cat8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF12">
        <property type="entry name" value="REGULATORY PROTEIN CAT8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="23"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="98"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="750"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="816"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="878"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="119"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="753"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="878"/>
            <end position="891"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1892173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="937" mass="101356" checksum="7FE669D1E3BC76EA" modified="2025-10-08" version="1">MPGIIPMKVIQVGKGSQSRIAQACDRCRSKKIRCDGLRPTCSQCSSVGFNCKTSDKLSRRAFPRGYTESLEERIRGLESENRGLKDALDEQDKRLEFLSKSRTPANQITTAIPSPPPSSSAASSTNGSTVAPASSQSPTRSSTHSAGTPPTSASSPEDTFKTPVPSLQLGVENSDSFFMGPSSGKNFIESFKRLMQEKAIHCPSFNSQVFLHMQGCSPLTSEVASNPPNLNSIPPRLFTDKCVNVFFQEWAPLFPVLHKPDFLRTYDEFMTDHSKVKSPHKLAQLYLVFAIAALSSGQTDTDQIAFCERHWQSFLDPLVLDSSISTLQCVILAMMYCTIRGNYKRLQYYRSIAVSACLRLGLHHKQKYFSFSALTVECRKRAFWTLYTVDCFAAALLGSPRLISDGWVETEYPIDADDEYISDAGIQPTLPGEVTRISSALALFRISRIMAKVLDTAYVSGAADLSVQTMNAFDQQLANWENSLPPHLKLVFEQDKPSTNMTGSRSPILALALNYIRVLTHRPALEAKPLSGNGANILTIGKTSKRIVQIIELLEERRMSFALCLNKADLLAISGLSLLYEGIKLGSHRNISMQGNVPLVNFVVKGLFRLKAPGCLEFKKAAAAFVRLEDGSVLRLQDEPKVMALHRPRSESGSISTARTKVANESSVSRIATGNGHSLQARLDIASASEPDLVAQAERIRRMTMPTMPSRPNLRTPTMGSFDLGKNSIIPAAPGDAGFDLFYPYGASSNTEVSKHGSRADLEASSLTPNRLSIDGDSSTEEALKTMMSSAMADSAVAEGTNHLFDMIYGNQHDIIMGQESSPSGSSGGHQQLPDGWNYNMHVSVGGGPPSLAISDTTAGSDEQAAAAVAAGGESSAAAGAEAAAGDLEASQMSPPEASPQQKAEFTPLVMNGLGNEDGYSMSFIGDNILDTFNSFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVN7</accession>
    <name>A0ABR3YVN7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RasGAP protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gap1</name>
        <name evidence="3" type="ORF">Cpir12675_004531</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000130">
        <property type="protein sequence ID" value="KAL1892448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05132">
        <property type="entry name" value="RasGAP_GAPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000593">
        <property type="entry name" value="RasGAP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023152">
        <property type="entry name" value="RasGAP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149:SF17">
        <property type="entry name" value="GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03836">
        <property type="entry name" value="RasGAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00323">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143885">
        <property type="entry name" value="RGC domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00509">
        <property type="entry name" value="RAS_GTPASE_ACTIV_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GAP" evidence="2">
        <location>
            <begin position="186"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="59"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="780" mass="89214" checksum="8D8A866514188864" modified="2025-10-08" version="1">MSVMLQPSRASTASTSSFPAISRFNTMSSYDGSATRSARQSKRFSMSALYMSMSANETELEIEDDLAKAQKVLRDLKAKISSQSKKNFVLEKDVRYLDSRIALLIQNRMALEEQNEVASHLEDATDIQEGFFPNDDKTQKYGNLLFLLQSEPRHIAHLCRLVSMSEIDSLLQTVMFTIYGNQYESREEHLLLTMFQSVLTYQFDNTPDYSSLLRANTPVSRMMTTYTRRGPGQSFLKSVLADKINSLIELKDLDLEINPLKVYERMIEQIEEDTGSLPPDMPRGVTAEQAAENETVRRAIEPRLQMLTDLANGFLTTIIDGLEEAPYGIRWICKQIRSLTKRKYPDANDQAICTMIGGFFFLRFINPAIVTPKSYMLIDGTPSEKPRRVLTLIAKMLQNLANKPSYAKEPYMAKLQPFIEANKDRVNNFMLDLCEVQDFYESLEMDNYVALSKKDLELSITLNEIYAMHNLIQKHQNELCKDGNSHLATIMGELGASPAQVPRKENRIINLPLFSRWETAIDDLTAALDITQEEVFFMEAKSIFVQIMRSIPSNSPIAKTPLRLERIADAAAKSKNDAVMVRKGIRAMELLSQLQELGVIDKSDQFAMLRDEVEQELQHLGSLKEGVIVETNKLSEVYKTIRDHNQYLVSQLETYKSYLHNVRSQSEGTRRKPQKQQVLGPYKFTHQQLEKEGVIQKSNVPDNRRANIFFNFTSPLPGTFVISLHYKGRSRGLLELDLKLDDLLEMQKDNQDELDLEYVQFSVPKVLALLNKRFARKKGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVX0</accession>
    <name>A0ABR3YVX0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Membrane protein ptm1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PTM1</name>
        <name evidence="12" type="ORF">Cpir12675_004946</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LU7TM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000153">
        <property type="protein sequence ID" value="KAL1891469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053937">
        <property type="entry name" value="GOST_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009637">
        <property type="entry name" value="GPR107/GPR108-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053938">
        <property type="entry name" value="PTM1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21229:SF1">
        <property type="entry name" value="GH17801P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21229">
        <property type="entry name" value="LUNG SEVEN TRANSMEMBRANE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06814">
        <property type="entry name" value="GOST_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21902">
        <property type="entry name" value="PTM1-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045440032" evidence="9">
        <location>
            <begin position="21"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="251"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="323"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="368"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="412"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="PTM1-like N-terminal" evidence="11">
        <location>
            <begin position="31"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="GOST seven transmembrane" evidence="10">
        <location>
            <begin position="184"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="455"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="486"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="523"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF06814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF21902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1891469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="558" mass="63209" checksum="890812F0FC34518B" modified="2025-10-08" version="1">MRSWLWSMAIMAMSFWVSHAMEVLMDQTEENKRQCTGMYSKSSWDGPVDPFINVIFHNNSIPDDRDPIVSLLVFEWRDMDLIGVKESDFPGERILVLCDDAQVSASACEESNKGQFVLAPNALNSSKLPIYNEAVHLKDPHVNMYPITKTGYYCVFTEPFTNDDYNAAAVFRNAYGELPATQVPKLPFYGGITILYALVAVYWGFLYYMHRHDILAVQNYITAILVFLVVEMLLTWAFYDYLNRNGRNMGVNIFMVIVGILNAGRNSFSFFLLLIVCMGYGVVKPTLGKAMIYARWLAVAHFAFGLIYAVTGLYITPESAGPFLLFVVLPLAATLTSFYVWTLNSLNDTLKNLRERKQNAKEAMYRKLWWCILLSIFITFGFFFINSLSFASVSDPDYVPFHWKTRWFVLDGWLNLVYFADVAWIAYVWRPTANNRRFAMSDEIAQDDDGTFEIADLGQPDGLSDSEDEEANIGNNHSRQEEGIIPSSSSMPVASITRNQPQAKPVQAHSKRMSEEIFAVGDGSDEDSDNELNDSGQSDDDSDEENAKLVRGQGKKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWB7</accession>
    <name>A0ABR3YWB7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peroxin/Ferlin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_004520</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000129">
        <property type="protein sequence ID" value="KAL1892548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006614">
        <property type="entry name" value="Peroxin/Ferlin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052646">
        <property type="entry name" value="Peroxisomal_PEX28-32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010482">
        <property type="entry name" value="TECPR1-like_DysF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31679">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX30-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31679:SF2">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX30-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06398">
        <property type="entry name" value="Pex24p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00693">
        <property type="entry name" value="DysFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Peroxin/Ferlin" evidence="6">
        <location>
            <begin position="377"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="146"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="330"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="509"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="605"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="177"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="330"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="528"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="556"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="621"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="640"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="666"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1892548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="713" mass="79635" checksum="0640181215E5CF01" modified="2025-10-08" version="1">MSNAKVRPDSLEALTTAGNELSTGIAPPTFAAFSPASLSTSASKAAPSRSTAKRSTILVHQKSPLLLATPPQITRALAYSHPFLLPLNKLAGLLTWTTGDPWESFLLLAAFWAIVLYGDVILRYAGPITVVLGLMVGMYSRRFSPLSSSGWSEPGRSDVKKEVGSSIGSKNGHRANSKSTGSSGDLSSHVRNPPAAENTNTRHQKTLDEIVETLKEFTARCDMLLEPMLTLTDFLSTQRTPTSATVRPALTTLFTRILFCTPFWFALTLPPLCIITTRRIVMVFGSLVLSWHSQPMRVCRTILWRSSTVRRTASIVTGLELHAPLKPTTPAQTLASRSSESDSAGQKPALESELTKQLKNQSLNHKLTGVKNTRDAGVKFTFMIFENQRRWVGLGWTLNLFGYERSGWTDENNNQVPSREEFELPDVEEGSQMRWRWVKGSQWRVDGVPLPEAGAADIDYDTEAGKMGWVYYDSKWQNGRRGADGWGRWTRRRKWYRDAELVEIDELSDSEATPVRSAEQLLEEEEDMTQKLRESREYERGRERKPRHLRDGGNKQQQEQQYQQSSSSGFDRKQRSGPLRASTGGFKPSTLGYSTAEEKIISPMRTEVARSYSPSISSLVHSEREQERDRDSYLDRDADSVSTMSTSSRSFFKSSTLKRRAEQRQSHGLTGLENSSNSDKASLLGVATELEIHGHGKESRAWGIGDEAHMCLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWS4</accession>
    <name>A0ABR3YWS4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004842</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000147">
        <property type="protein sequence ID" value="KAL1891769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046591">
        <property type="entry name" value="DUF6649"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20354">
        <property type="entry name" value="DUF6649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="384" mass="42024" checksum="B4323753E01C6D6F" modified="2025-10-08" version="1">MASMSAYSQPQPPTSASPVQDSRCQRQLLQLQHMQMQMQMPVSAQMYSNSKQPSPTQGQNQSFPAQAQAQAQAQAQQKYLDCHSSQYNAQETPISPVSPLSTYPLVSASALAPSPSPNAPTPSFSQQKRKRKAESQDAPGNERLSKRLSLLNLERNGPKLYVPVEAPSSSTPCVTTLDAEVNAAAGAANNRRCRPAPQDSGHMMQLDDSRHKVYIYNLDDELSSSESEPEDGRLIMLPDIKKHLLENRILPSVKASPEGQLAGMQLVLYREPKALTVPEADDSVRKVVVEARQRIRDRIKQEEEAAAAAAATSSNSGPMLTSSSSVASPQPPSSFATPFYNIPSFPQRQQQPSHVDPEPSAWQQLQQPALYSDAMDMDVDMDID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXG8</accession>
    <name>A0ABR3YXG8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Proteasome regulatory particle subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPN5</name>
        <name evidence="4" type="ORF">Cpir12675_004270</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit p55 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000117">
        <property type="protein sequence ID" value="KAL1893079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054559">
        <property type="entry name" value="PSMD12-CSN4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040134">
        <property type="entry name" value="PSMD12/CSN4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040896">
        <property type="entry name" value="RPN5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855:SF1">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22241">
        <property type="entry name" value="PSMD12-CSN4_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18098">
        <property type="entry name" value="RPN5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="3">
        <location>
            <begin position="258"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="492" mass="56530" checksum="716B49E1ECFCF9AB" modified="2025-10-08" version="1">MADAAFKPEKDYSKQVDDALPEAKKLAETDLLGAIEKLSILEKQTRQASDLASISRILIAIVTLCKDAKDWGLMNEQTLILSKKHGQLKLAITKMVQKVMEFIPETPNLDTKLTVIETLRTVTDGKIFVEVERARVTKELSDIKKSQGDVKKATEILCELQVETFGSMERREKTEFILAQVALCIEIGDWIQAGILSRKISTKYLARPAKPLPEQIKRDEEENRLKKAKGEKVVVKKIDDVTDLKLKYYEQQIILAKHDSKYLEVCKHFRQVLDTGVVEENANKLKPVLQRIIYFIILAPHDNEQHDLLQRIFRDTRNTQIPVEAQLLKLFTVQELLCWPQVVRQFGSHLCETDVFDAKEGDSEDEKSHQRWLDLKKRVIEHNVRVVAKYYTRIRTTRLTQLLDLTETETEKYISELVTSKTVYAKIDRPAGIVDFSKPRDANDVLNEWSYNMKSLLGHLERIDHLITKEEMMARISKPKAGKVATKGKPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXU1</accession>
    <name>A0ABR3YXU1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cysteine-S-conjugate beta-lyase</fullName>
            <ecNumber evidence="3">4.4.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cysteine-S-conjugate beta-lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">STR3</name>
        <name evidence="10" type="ORF">Cpir12675_004234</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.13" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000115">
        <property type="protein sequence ID" value="KAL1893215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047804">
        <property type="term" value="F:cysteine-S-conjugate beta-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006238">
        <property type="entry name" value="Cys_b_lyase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054542">
        <property type="entry name" value="Cys_met_metab_PP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01329">
        <property type="entry name" value="cysta_beta_ly_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808:SF50">
        <property type="entry name" value="CYSTATHIONINE BETA-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="TRANS-SULFURATION ENZYME FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="5 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1893215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="435" mass="47058" checksum="E522ED6B6C20CA3B" modified="2025-10-08" version="1">MSCSVVEDSKALKLDAGDVLPPSPAPSSPLNGRLRYNIETELVYTDSRDQYGASSVPIYQTATFKQITATGGQQEYDYTRSGNPTRSHLERHLAKIMNASRVLAVGSGMGALDVITRMLRPGDEVITGDDLYGGTHRLLTYMKNNQGIIVHHVDTTAVESVGKLVTEKTAMVLLETPTNPLIKIVDIPSIARLVHEANQKALVVVDNTMLSPMLSNPLDLGADIVYESGTKYLSGHHDIMAGVIAVNDTAIGDKMFFTINSTGCGLSPNDSFLLMRGVKTLAIRMERQQANAQKIAEFLENHGFRVRYPGLKSHPQYDLHWSMARGAGAVLAFETGDAAVSERIVEAARLWGISVSFGCVNSLISMPCQMSHASIDAKTRAERQMPEDIIRLCVGIENAQDLIEDLSRALVQAGAVTVKPSGFTASTPITTTTAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXV8</accession>
    <name>A0ABR3YXV8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidylinositol transfer protein (PITP)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PDR16</name>
        <name evidence="3" type="ORF">Cpir12675_004307</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000118">
        <property type="protein sequence ID" value="KAL1893073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052578">
        <property type="entry name" value="PI_Transfer_CRAL-TRIO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45824">
        <property type="entry name" value="GH16843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45824:SF29">
        <property type="entry name" value="GH16843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="105"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="344" mass="38753" checksum="27CD32A3AD153E1C" modified="2025-10-08" version="1">MDQVVKTPLAQPAPGCTPSPRTPLTAEEETKYTSLLARSRSWTEVPSTKGKAGPLTDDERMWLTRECLERYLRATKWNEREAEKRVLGTLTWRREFGLDGLTPEHISPENETGKQMIYGFDKECRPCLYLSPGRQNTQASHRQVEHLAFMVERVLDILPPGQETLALLINFKPAKGQKSSGPSLSLAKECLNMLQMHYPERLGRALIINVPWVIWGFFKLITPFIDPRTVVKLKFNEVMSQYVPEEQLWNEFEGGKLNFEYDHSVFWPALWKMTQDSKAARKERWVAGGKHIGEHESYLFGGDDKGLAASLAAGSAVASKSEASNPKVDADTTAVKAEKETSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXW2</accession>
    <name>A0ABR3YXW2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004382</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0235 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000122">
        <property type="protein sequence ID" value="KAL1892799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1200.10">
        <property type="entry name" value="YggU-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003746">
        <property type="entry name" value="DUF167"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036591">
        <property type="entry name" value="YggU-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00251">
        <property type="entry name" value="DUF167 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13420">
        <property type="entry name" value="UPF0235 PROTEIN C15ORF40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13420:SF7">
        <property type="entry name" value="UPF0235 PROTEIN C15ORF40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02594">
        <property type="entry name" value="DUF167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01152">
        <property type="entry name" value="DUF167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69786">
        <property type="entry name" value="YggU-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="77" mass="8690" checksum="2463341AAF2E32C2" modified="2025-10-08" version="1">MDENVIELCVSAQAREGEANKAVIQTFSEVLDMPKSDIRISHGHKSRDKTIVVTRVSADEHKALQWIRTRLADSIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYE4</accession>
    <name>A0ABR3YYE4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Translocase of outer mitochondrial membrane</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TOM40</name>
        <name evidence="10" type="ORF">Cpir12675_004144</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tom40 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000111">
        <property type="protein sequence ID" value="KAL1893406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07305">
        <property type="entry name" value="Porin3_Tom40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="entry name" value="Porin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027246">
        <property type="entry name" value="Porin_Euk/Tom40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037930">
        <property type="entry name" value="Tom40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10802">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01459">
        <property type="entry name" value="Porin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1893406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="351" mass="38098" checksum="FDFF385894AD963B" modified="2025-10-08" version="1">MAAFMDSVNAFLASNPLAKSVADALDSYSERRQKLGLPNPGTSELLTKEVQREVLPSGYMFSGIKADITKIVGTSPFFQVSHQFAMGERQSPYAFATLYGTDDVFMQSQLDNEGTCSARMNYRWSPSLMTKAQVQMSPNGNMAQFDHDYTGSDFTASLKMINPSALSGGLTGIFLGSYLQSITPKLALGFESVYQRPAMTQGPETALSLMGRYKTEDWAATAQLQAQGAFIATYWKRLSDKVQAGVDMQLSLTPSPAMMGGGISKEGLTTIGLKYDFRMATFRAQVDSSGKIGCLIEKRTQAPVSLTFAAEFDHWTQTPKIGLGLSVESQSEELQAAAELGTPPPMPNVPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYL5</accession>
    <name>A0ABR3YYL5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_004567</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000132">
        <property type="protein sequence ID" value="KAL1892414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1892414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="114" mass="13246" checksum="56A86DC12292EA4C" modified="2025-10-08" version="1">MRSVEVQRRGNSYNHDVAFNIIFAEYTTPKPQLRTMVEGIMGFLDDESFQIEGDNQLANLWTQLGLREAYGNYDHMLPSYLVSHATGIDYKAFCKVYVLEDEDVLVPYTTYYKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZC0</accession>
    <name>A0ABR3YZC0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Methionine aminopeptidase 2</fullName>
            <shortName evidence="9">MAP 2</shortName>
            <shortName evidence="9">MetAP 2</shortName>
            <ecNumber evidence="9">3.4.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Peptidase M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">MAP2</name>
        <name evidence="13" type="ORF">Cpir12675_004194</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9 10">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="9">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000113">
        <property type="protein sequence ID" value="KAL1893261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004239">
        <property type="term" value="F:initiator methionyl aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01088">
        <property type="entry name" value="MetAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03175">
        <property type="entry name" value="MetAP_2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050247">
        <property type="entry name" value="Met_Aminopeptidase_Type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002468">
        <property type="entry name" value="Pept_M24A_MAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018349">
        <property type="entry name" value="Pept_M24A_MAP2_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00501">
        <property type="entry name" value="met_pdase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45777">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45777:SF2">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01202">
        <property type="entry name" value="MAP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 9 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M24" evidence="12">
        <location>
            <begin position="129"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="58"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="425"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="425"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1893261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="444" mass="48222" checksum="97D92FC4F19F6E8E" modified="2025-10-08" version="1">MAAQAPTEALEKLSVTDASAPAVAAEKADPAANGNAADSDGDDSENEGVTDPAATGAAKKKKKRKPKKKKKATPKEQTSPPTVPVSVLFPGRNYPKGEEVEYLNENNFRTTNEEKRHLDNIKADFLSDYRAAAEVHRQVRQHAQKTIKPGQTLTDIANNIEDSVRALTGHSGLEEGDALIAGMGFPTGLSINHCAAHYTPNAGNKMVLQQGDVMKVDFGVHVNGCIVDSAFTMAFEDKFNPLLEAVKDATNTGIREAGIDVRVGDIGGYIQEVMESYEVEIDGTTYPVKSIRNLNGHSILPYSIHGTKSVPIVKSKDMTKMEEGDVFAIETFGSTGNGYVHEDMETSHYAKTGDASNVPLRLSSAKHLLNVITKNFGTLPFCRRYLDRLGQEKYLLGLNNLVSAGIVEAYPPLVDKKGSYTAQYEHTILLRPTVKEVISRGDDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZP9</accession>
    <name>A0ABR3YZP9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Small subunit (SSU) processome component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">UTP5</name>
        <name evidence="6" type="ORF">Cpir12675_003955</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UTP5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000102">
        <property type="protein sequence ID" value="KAL1893836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007148">
        <property type="entry name" value="SSU_processome_Utp12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052414">
        <property type="entry name" value="U3_snoRNA-assoc_WDR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44267">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44267:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04003">
        <property type="entry name" value="Utp12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small-subunit processome Utp12" evidence="5">
        <location>
            <begin position="164"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="44"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="274"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="80"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="276"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="329"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1893836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="392" mass="41989" checksum="048C440CF4BCCD17" modified="2025-10-08" version="1">MVSQAKRKAPSKITAPRLQTSAKPVTKAAINEIKAAVSMADIVKLPKKQRDADTIEISSDSDSNDDDSDPDEEMAEGDESTAAVASISASTTAGVDAEDSDVDGTSPTFGELVHTQETVDVSAALATRSSTAQALASTTQQRTVAAPSLSSLSTVLTQALRTDDAELLESCLATANLATVRNTIERLDSALAGSLLSKLAARIYRRPGRAGTLLQWVQWVLVAHGGALASQPEVMAKLATLQKVLVERSRGLNSLLVLKGKLDLLESQMQLRKKMQSKESRRDNAEEIEDENVIWVEGAASDEATRRGAAGDDEDDYDEVPTANGIMGDSDEEDDDEEDDDDDDEDDDEDDEDEDDVDHSDVDESGEDDESEPETAPPTKMRKTGGGFTKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1L8</accession>
    <name>A0ABR3Z1L8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">NET1-associated nuclear protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NAN1</name>
        <name evidence="10" type="ORF">Cpir12675_003832</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000097">
        <property type="protein sequence ID" value="KAL1894097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23952">
        <property type="entry name" value="Utp17_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053826">
        <property type="entry name" value="WDR75"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44215">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44215:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23869">
        <property type="entry name" value="Beta-prop_WDR75_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="344"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="604"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="867"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="881"/>
            <end position="890"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1894097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="962" mass="104185" checksum="F89047D15A08E60E" modified="2025-10-08" version="1">MAGSAISATTLKRKHLSESKSQKKRQRPVTTEAIVDRTLVTSKPQDEVTARDSSASPQVQSEWTVSKASGGRIVDIDPILTEDQRFLIVPYTTSIQIYSTADSLLVRRIPMPSPNRNLGIVGLRQCLTDPSMVWVACANGIISKVNWTGESETPIVVSIPTASGTASSLATLLVSVGDSDAKKTSAEVVLVAEIPSDHSPTRVIAYDGELRLIKVLLKLADGMSKLHNMETLVGAGLVYASAGKQFYLGTPQSLELASLDELAYEFYTFACEDLITATDARAVPLSRSKKESSKQQQMSIDVAIGCARGPIYCYSDILTRLQAMDAATATASKGPREALQPKKMHWHRRAVHSLKWSRDGNYLVSGGSEHTLVLWQLDTNKQSFLPHLSGIIENIVVSASGSAYVIHLDDNSVMVLSSAQLEPTAYISGVQSAVYVNSALKDHLVPRTGEKYSMSNIEVVMALNPAAPERMYLCVGDGLQASRNGSKPYLQSVDLSSMRSIGKQAIARTSLTANNTTPSGATIIDPEIKHMAFSCDGKWLATIDEWIPPSNSQANLGASEGDSELRKERREVFLKIWDAETAVESESQENAPLSLVSRINTPHETSHPESVLDLAADPQNARFATLGRDGIARIWKPRPRQRDGLAIKDDRGKELHTWICDIAVTVNHRQSIVAMSGADYSRIEGRLSFADDGSCLVAAFGAGDEGSIHVIDAHTGHVRYSWDDLWRGSLHGLQLLGPYVIVLSHDLRVFDMVADSLVYGLPLAKPSNLDISSGAANLAIDRMSRHFAVSLRHTEGSELLIFSPNSMEPLLSHHFESRIAALSASAEPHTSGFLVLDNEAQVFTVSQASNDNGLVVARSLDEMQLDAAEEKPSTNGVELLDGSDDEDEGEPGQNGKPEAMDIDTPDAMEIDAHEDSSSHPAIINKHQLSDIFDAAPTYAMVPLEDLFLKVAALLANKPVGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1P1</accession>
    <name>A0ABR3Z1P1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pre-mRNA splicing factor CLF1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003776</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000095">
        <property type="protein sequence ID" value="KAL1894134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12841">
        <property type="entry name" value="TM_EphA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="414"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="502"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="549"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="502"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="768" mass="79839" checksum="E838948BD0712CB8" modified="2025-10-08" version="1">MSYKSSPISLAGACTAIHDNVLYAYSASGFVKLPLKNGTEWTKLASGEAVSDATCVGAEATDASKSALYIMGGTSTNGAYNGIQRYVYSTGVWETLSTTDPVLKNRKGMSAAYIPATDSFITYGGRTDGTYGVDSQTFSIKASAPYTVISAVNPFSYTLQTPIMLGWVDGEVLLAGGSTTNLDLIIYNAGTNTWRRSGGSLADPVAKVTNKGYLQKGDDGSRSLYTFDLAQSPVRVTRSVIVDATGGFVTKSNTIVAARQLSSANWPAYNSTFAPAPASGEVYSAAANSDGHVFFLTSDASNPVSAFDATQNSWVDVDSELASQSVLIADVSSSTTLRSSTTTSATSTASSSGSTSATTFASKTTSSFSITSSVSSTTSGASTTNSSLSATASSTELGAASSEPSKGGLSSNDVLGIVLGSILGSILLLVGILFFIKKARRRKGYTGENNRPHNEFSNAEKNVGMGMASEQFVDSIGGGPRARNNTDSVASLAIFGGVGASAAGRSASPAFSTGGGNSKNLRRKPSDPQSTNIAKNLKSTISKPIMANDSSLMAGGKDRISINTPGRSPPLPPGSQPALAPERHLMDDATRRSSGWNKYWSQGSGALNALSYSNGHNDDDGATSHYPSTYSAVDNINRRTQDSATVPPLIMPHEGRPELNRVASGSPTVSHYAKYATAQAQVAAIERPVSDAQSAYSSGVAPSVQEAWGPISQQKAWGADSVYGAHGQNVSGGIAYEGSQNQDPRLAMTTQSSDMSWLNLGEYKRANH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1V7</accession>
    <name>A0ABR3Z1V7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003598</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000088">
        <property type="protein sequence ID" value="KAL1894609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF8">
        <property type="entry name" value="BENZIL REDUCTASE ((S)-BENZOIN FORMING) IRC24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="249" mass="26276" checksum="8AC9CC6CB86A0C89" modified="2025-10-08" version="1">MSAKTILVTGASRGIGLNIAKALVAADHQVVVTARSTEELEKLKLIAPERVAYLAGDMADFSLPSRLVDLAVSTFGGLDGVVVNHGVLAPINKLADAPLDEWKSLYDVNLFSGIALAKAAIPALRTSRGMVVWISSGAATNNYTSWSAYGSSKAAINSISAHLAAEEPEITSFALAPGVVATDMQTQIRSSKNMDPTQLARFVDLHQSDKLLKPEWVGAVVAKIVTKQDGTLSGKFLRITDPTLAAYAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1Z1</accession>
    <name>A0ABR3Z1Z1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ATP synthase mitochondrial F1 complex assembly factor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">atp12</name>
        <name evidence="7" type="ORF">Cpir12675_003605</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATP12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000088">
        <property type="protein sequence ID" value="KAL1894616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3580.10">
        <property type="entry name" value="ATP12 ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2180.10">
        <property type="entry name" value="ATP12-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011419">
        <property type="entry name" value="ATP12_ATP_synth-F1-assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042272">
        <property type="entry name" value="ATP12_ATP_synth-F1-assembly_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023335">
        <property type="entry name" value="ATP12_ortho_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21013:SF10">
        <property type="entry name" value="ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21013">
        <property type="entry name" value="ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2/ATP12 PROTEIN, MITOCHONDRIAL PRECURSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07542">
        <property type="entry name" value="ATP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160909">
        <property type="entry name" value="ATP12-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="16"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="23"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1894616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="366" mass="40146" checksum="231EBDEFB4B4A57E" modified="2025-10-08" version="1">MSALFVPSLARSALSRTLGRPRTAASSATALLHTTSTPSANVSPLIGTGPPPEPPVPSPEAVSAQSRVARRRRQAEMMRAARTFRDGSDKIKTVRKRFWEHTSVKEVDGLLQVFLDARPLRHPTTKEIVCLPRTKHALATALAIEWDQLSSAQDTTKSHLLPLTSLVCRALDIAADDACATPTIRPTALPLLLRYLDTDSVLCWAPEPEAALREPGASLREIQREAAKPLVSWLSQRVWPGARIEPVLDSDSIVPRRQDTATRALVQQWAQGLDAWDFAGLERAIISGKSFLVAARLVSEWSSSAGVLPDGEVQSFTADEAARVANIEVDWQTQRWGEVEDTHDVEKQDIRRHYGSVVLLVSGSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z242</accession>
    <name>A0ABR3Z242_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Acyl-protein thioesterase 1</fullName>
            <ecNumber evidence="2">3.1.2.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Palmitoyl-protein hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_003607</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Hydrolyzes fatty acids from S-acylated cysteine residues in proteins with a strong preference for palmitoylated G-alpha proteins over other acyl substrates. Mediates the deacylation of G-alpha proteins such as GPA1 in vivo, but has weak or no activity toward palmitoylated Ras proteins. Has weak lysophospholipase activity in vitro; however such activity may not exist in vivo.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19233"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:7896"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="3.1.2.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.22" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000088">
        <property type="protein sequence ID" value="KAL1894618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050565">
        <property type="entry name" value="LYPA1-2/EST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655:SF17">
        <property type="entry name" value="LYSOPHOSPHOLIPASE-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655">
        <property type="entry name" value="LYSOPHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
        <property type="entry name" value="Abhydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0719">Serine esterase</keyword>
    <feature type="domain" description="Phospholipase/carboxylesterase/thioesterase" evidence="10">
        <location>
            <begin position="7"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1894618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="218" mass="23879" checksum="CE913E2E7BB46400" modified="2025-10-08" version="1">MAYPAPLIVPAVSKHTATVIFAHGLGDTCAGWIDVVRNWRLRSKLNQVKFVLPNAPTIPVTCESLNGTIESLLKNEDEKGILETRNYLSGLIKAEIDAGIAPERIILGGFSQGGAVALLTGLTGEHKLGGIVALSCWLLLSGKFKELLKDELADTPIFMAHGNEDPLVIPQFNDMSRQKLQELGVKLDYHSYPMGHTACVEEIEEVSQFMEKQLPMLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2P3</accession>
    <name>A0ABR3Z2P3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">U1 snRNP protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PRP40</name>
        <name evidence="4" type="ORF">Cpir12675_003713</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000092">
        <property type="protein sequence ID" value="KAL1894330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.440">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002713">
        <property type="entry name" value="FF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036517">
        <property type="entry name" value="FF_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039726">
        <property type="entry name" value="Prp40-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11864">
        <property type="entry name" value="PRE-MRNA-PROCESSING PROTEIN PRP40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11864:SF0">
        <property type="entry name" value="PRP40 PRE-MRNA PROCESSING FACTOR 40 HOMOLOG A (YEAST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01846">
        <property type="entry name" value="FF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25432">
        <property type="entry name" value="FF_PRPF40A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00441">
        <property type="entry name" value="FF"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81698">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51676">
        <property type="entry name" value="FF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="2"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="48"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="FF" evidence="3">
        <location>
            <begin position="244"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="FF" evidence="3">
        <location>
            <begin position="390"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="FF" evidence="3">
        <location>
            <begin position="527"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="579"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="607"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="627"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="637"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="650"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="682"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="798"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="824"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="851"/>
            <end position="866"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="902" mass="105780" checksum="54A191A51368039F" modified="2025-10-08" version="1">MSTSAGAWQAHTSGEGRTYYHNTVTGATQWEKPEDMMTPAERALANQPWKEYTADGGRKYWYNTETQQSSWEIPEVYKLALGVPASSTPSIPHRVGFASAAPDRHDSRDYRDRDRDRDRDHRDYRDRDRDRDRDRDRDRDYHRDNRGERDSYRPGAHNLESMGPVFVPTIPDPEFASAEEGEAAFFKLLKRSGVQYDWTWKQAIRASAKDPHFRAIRDPRDRKLAFDKYCQNVVEQDREKAKERMTKLRSDFETMLKSHDEIKHYTRWKTARAIIEGETIFRSTNNEDERRQLFIEYVVGLKKAHTENQSSQRKAAMDGLIEILGSLNLEPYTRWADAQTQIFNAPLFKSEEKYQSLSDFDVLNSFQSHVKALERTFNDSKQQNKIKKYRSERKNRDTFLDLLTELRKAGKINAASKWSKVFPLIENEERYIAMAGQSGSTAQELFWDVVEDEEKSLRNLRNDILDILDDKRFEVTSKTTFDEFQAVIKDNPRVADTDPDILTLLFERLQEKKLKRSDEERYPERLQRKAAENFKTYLKRLEPPIGSSDTYEKLKPRISRSDEFQYLYSDETRRSIFEKVQRRNKERDEEERDRQQRRRGTAVVDRASSDRDLYRERDGSRGERSHRSGAGRRRSRSPATPASAEADPYEADRRKAIAERERNNSRRNAESLLDPSATTTARSDRERPRSRDRERDRDRERDRDRDHDRDKDRGNRDRERDRPRERDREYDRHRSRRDEGSYYERDRHPRDDDRIYRRRTERGGSFDELNYDDERPSAARRRRNDEEDDRRDSKRQRTIRERTPREKTPFRDQRPSKKSPAPEPSTTSSNNGVAATDSSANGSSGKRQKSPADLSASKSSNSLAAPTKEANKTTGKSGKAAVATTDDDVAMNSGSEEGEIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2T1</accession>
    <name>A0ABR3Z2T1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">UBP9-binding protein bun107</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_003943</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat WDR48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000102">
        <property type="protein sequence ID" value="KAL1893824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17041">
        <property type="entry name" value="Ubl_WDR48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051246">
        <property type="entry name" value="WDR48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021772">
        <property type="entry name" value="WDR48/Bun107"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19862">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19862:SF14">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11816">
        <property type="entry name" value="DUF3337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="23"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="99"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="144"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="232"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="67"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="675"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="730"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="912"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1006"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="689"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="949"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1011"/>
            <end position="1024"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1893824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1034" mass="112707" checksum="FE6FA7538CB9FC2D" modified="2025-10-08" version="1">MASKKARQRISYVLDLPQSSNGEGGHRLGVSGLAIDRESSILYSGGRDGMLCAWDLNLNLMSKPSISDTASNHTDSSINADSLNQTPNSRTKSTMRMQTQAHTHWINDIALVQNSRTVVSASSDLTVKVWRPHSEIDQYMTHKIGEHADFVKVVAAPPHSPWVASGALDRKIRLWDLNGGGMTLEIDVSGEEKPEKGSVYALAVSRGLMACGGPESVVRLMDPRTGQKVSKFVGHTDMIRDILLSESGDTVLTASSDNTIKLWSVTAGRCMYTYSMHSESVWALASEASDLSLFYSADRSGLIVKTDVRSVAEDLDRGLSLALAKENNGVLRIAPAGDFFWTSTASSSINRWHTVNTDSVRLRSAESSHLEGGVGAHQRALSSTTVVTTPTVVLPSHIPASSVLRISNTAGFPAFVRRDGENPAPNDNFAIEDPETSAVEPIHHLAEETIEGQNGLVKHVLLNDRRRVLTLDTAGEVLLWDLIQGIPIVNYAKRDLLSILPVVNTIEAVAPWCSVDISSGSLTVILEPYNCFDAEMYADELTMKVDPEIEFREDQRINLGKWVLRYLFSGLVDEEIRRDEIYRQNLNDAIDLRLGKPKSVSMQNNFGSTSQGLALTDQGPAPPTHGMANLSAGTPLVPVSSQLSQLSRVSQDDDVSSVIPADGAFKNGLSTGLVASGDTSTSPIVDPLIAKEKEEDKDDSAKEKETKDKDGKGMGFKKLYMGMSFGKQKNRTVSAPTAEKTPAALDEKAEESETASILEKEVNDSFYGAIQKIHMEYDKQLLELPDQPVETRLIPSLPSETPTLVFPPKTKVIIQEETSSGGSANIYMGTVSSVGNDADVIEKRGPMWLGDVLLQGLMPYKEPVKVSFVLHPWQDSLPRIAPADGNNRLNANRMLRVRKILGYVADKIDPIPQPKIKPARMRQEGMEQAPGSGGTAQDGMGSQNQQGEDALDEEEEEEEGEARPNPEEYLELYCNDQLLPVSMSLATLRAHVWKSGSDVTLYYKSNGRRTIPPPPPPPMIPPEEPATAQISAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z398</accession>
    <name>A0ABR3Z398_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proteinase inhibitor I78</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_003388</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000079">
        <property type="protein sequence ID" value="KAL1895116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.10.10">
        <property type="entry name" value="Trypsin Inhibitor V, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39600">
        <property type="entry name" value="PEPTIDASE INHIBITOR I78 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39600:SF1">
        <property type="entry name" value="PEPTIDASE INHIBITOR I78 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1895116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="87" mass="9598" checksum="FD567EA92BC202D3" modified="2025-10-08" version="1">MPLIVPGLQNVDAQSSDANSQSAWEKQLMGKTLNTDGKTDELTFAVKDLPEVHRIIQPGQNVTRDTDENRLNVLLDGDGTVRNVYFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3D1</accession>
    <name>A0ABR3Z3D1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8004 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003375</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000078">
        <property type="protein sequence ID" value="KAL1895146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058317">
        <property type="entry name" value="DUF8004"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39601">
        <property type="entry name" value="CHORIOGENIN HMINOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39601:SF1">
        <property type="entry name" value="CHORIOGENIN HMINOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26013">
        <property type="entry name" value="DUF8004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8004" evidence="2">
        <location>
            <begin position="184"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="558"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="603"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="780"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="607"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="658"/>
            <end position="693"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="837" mass="94133" checksum="98AF69CD6E273CA1" modified="2025-10-08" version="1">MSSYESARARRFGDFMEGRLPQTAQLKRWDGAARVSQDWDKLKKDPELWDRNGTCLVYLFAQGTSRRGPSFRVPLSSLLAARCHPLIERYAARGVPDSIISESSSYAGYDMWYRANPTRCVELYMTAPPNADKRQASRFHLATRNFFAWICRRSLVGDHLGGAIVTLMRTMQQFRLPGTNNIYDLLDFLEEEGYLNMQNLPNHALAILYVSEYFQFREMYIDAFVHCVGMNSQLFLSSEYRYTSSVSQKLIRRAREDYDLRLNKTSLMLQCFLRDEFSEQHLGLTAGARHHMERFRNFLIKFYHEEFGNYPPKSVESRTLVFSKEVYDRMRCDFECLYELLVDDSFTSCQNTPLLAQGGLCTVQSVNSFDLQWRFKPLLHPLPKLPQVVVPNNARGMSLTSWLSRTEKPKPDNQLVQLSALAAASNSTKSSTSMNSMVQAFCEFERRCVVEPSKLEKKEKLSLVDARKVRWILVYGIYQTLRSVTEPPMEVREIESTRYLVAVSTANLPPWKEAIRRTQSVRRNTDPYIAANMTMPTGTDIFMSEIQPDIDYLAPKHRNNSAPHALSSHGHPNNSNVGRAMSLGRSFAQGEMFRRLSIFKNPKWHNDSQQNPTPTNAFEDQGSPVHGHQNVVYDLPEPSPSTHVDMSARMANLQHRPSTASGVMSSSASTASRSHSTASNSSAGTSSTVDSYSTANTSAPAISPKAPGRTLSWEGKRVTNMPMRRRSAACIPVSTQRIGSSPPSPITQGFTAQEQDVSCRRPRTSANTRAPLAQPSFNAAPKLAIPNPRTRPSYGNGSRSRTLPLRIHGSPSAAVMAADEGGTEWEMYSNIGGHTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3J8</accession>
    <name>A0ABR3Z3J8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ras-related protein RABB1b</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003472</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000083">
        <property type="protein sequence ID" value="KAL1894827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00154">
        <property type="entry name" value="Rab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="56"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="75"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="87"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="284" mass="30444" checksum="56E463E410A30C49" modified="2025-10-08" version="1">MASAPTWDYIAKLVCIGDSGCGKSSLTIRLCEGRFSAHHDVTIGVEFGSRIVPVGPPHSDTYAPPSLAQGSQDNTTSSSPLSSSATTPPPASTATGLPPPPRKPKTNSKDARDLPLPQKHMKLSLWDTAGQETYKSVTRSYFRGASGALLVFDLTRKQTFDHVTDWLADLRQIAEPDIVVVLVGNKADLTVEEGGNGNGKREVTRAEAEAWARANDILEYVETSAKSGENVESAFMHVAEQIHMNIQAGKYDLNDRRSGVKGHASATGQRLAITADKAVKRGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4X4</accession>
    <name>A0ABR3Z4X4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">NADH-ubiquinone oxidoreductase 14.8 kDa subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_003306</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I LYR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000076">
        <property type="protein sequence ID" value="KAL1895289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20266">
        <property type="entry name" value="Complex1_LYR_NDUFA6_LYRM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045299">
        <property type="entry name" value="Complex1_LYR_NDUFA6_LYRM6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016488">
        <property type="entry name" value="NADH_Ub_cplx-1_asu_su-6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12964:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12964">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE B14 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13233">
        <property type="entry name" value="Complex1_LYR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006643">
        <property type="entry name" value="NDUA6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1895289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="124" mass="14717" checksum="8BE7ACC6A45C2C32" modified="2025-10-08" version="1">MAVLPTELAVRVRQSANWSDAKLRVIHAYRDWMRAAPTIQTMYNVSKPVPAIRTRIREEFEKNRFINKINHVDVLVTKNNAEYQETMNFWKQTPHVMSYFRDENWRAGDRLPSNFMSGFLEGRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5P6</accession>
    <name>A0ABR3Z5P6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">WW domain-containing protein wwm1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">WWM1</name>
        <name evidence="3" type="ORF">Cpir12675_003474</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000083">
        <property type="protein sequence ID" value="KAL1894829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="16"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="195"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="308" mass="31965" checksum="DB5FA2AE13813202" modified="2025-10-08" version="1">MADFAPPSGPPPPQEPQVPPGWTARWNDQYKQWFYVNLYTKQSQWEVPREPVYPPNEATPPGAPPGYVPDHNQPAPSDTKKNPYDTAPSNQEEEDAALARRLQEEENTRFHNTGNASGNPNYNDVGASTSYHNASSSNTPTPYDATSTANSTPVNGGEEKRGLMGKLFNKASGKHSGAGGTAAAGGLGGLLGSLAGRHSSHSKPSYGGGGGYPQPGYNNGYPSQAYGQPGYGGYPPQGGYYGQAPPKKSGGMGKMGGAALGLGAGVLGGALIAGAIDHEENEAYADGYMDGQNDDFGGGDFGGGDFDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z667</accession>
    <name>A0ABR3Z667_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_003320</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000076">
        <property type="protein sequence ID" value="KAL1895303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1895303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="237" mass="27158" checksum="3E90FCE564371D13" modified="2025-10-08" version="1">MPMLRWAPSIETVHLIGRNTDVSWRELPHESMTQPVDFVSINQGVFRLMNNVKCLHLENLVRIKNFLGPLWPDEKNPQPFLETNPLKDTSPFYTLMVLDIQYSSLHFPITWEDDVNDLNDHPETQDWRQRVSLGCARLALLIPNLRLMKVWQRPLMYAGKHSLMYKVSGLGDPAIPTTTSLEWNSTFGFAPWKVTLQAWAAVAAKNAGVDNLQVKISMEKNWRTDGQPPKFPALVPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6D4</accession>
    <name>A0ABR3Z6D4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTP:AMP phosphotransferase, mitochondrial</fullName>
            <ecNumber evidence="5">2.7.4.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Adenylate kinase 3</fullName>
            <shortName evidence="5">AK 3</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">ADK2</name>
        <name evidence="8" type="ORF">Cpir12675_003110</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a ribonucleoside 5'-triphosphate + AMP = a ribonucleoside 5'-diphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:13749"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.10"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="5">Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the adenylate kinase family. AK3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.10" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000068">
        <property type="protein sequence ID" value="KAL1895777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03169">
        <property type="entry name" value="Adenylate_kinase_AK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007862">
        <property type="entry name" value="Adenylate_kinase_lid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028586">
        <property type="entry name" value="AK3/Ak4_mitochondrial"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05191">
        <property type="entry name" value="ADK_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Adenylate kinase active site lid" evidence="7">
        <location>
            <begin position="185"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="NMPbind" evidence="5">
        <location>
            <begin position="37"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="LID" evidence="5">
        <location>
            <begin position="184"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="16"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="64"/>
            <end position="66"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="148"/>
            <end position="151"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="194"/>
            <end position="195"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="274" mass="29969" checksum="1F455D6A3A577839" modified="2025-10-08" version="1">MQLRKAARVILVGAPGVGKGTQSERLLKRFPQLQTISSGDLLRSNVKRRTPLGIKVENTMKAGGLVSDDLILRVIGNEFYQRGWISLPAGHSAMTLASSGEASAVALEPESEPPLAASNSFVGTPSVLESVPRPIFSDDPACSFLLDGFPRTQGQAASLDRVVPINLVISIITPFDVLLRRITSRWVHEPSGRVYNTAFNAPRVAGRDDVTGEPLKQRSDDTEDVYRARYVKFQETAGPLLEHYARRGLVMEVEGMSSDEISPKLFEAFGRMYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7Z9</accession>
    <name>A0ABR3Z7Z9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Diphthamide biosynthesis protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">DPH4</name>
        <name evidence="14" type="ORF">Cpir12675_002908</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DPH4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000062">
        <property type="protein sequence ID" value="KAL1896201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.660.10">
        <property type="entry name" value="DPH Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044248">
        <property type="entry name" value="DPH3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007872">
        <property type="entry name" value="DPH_MB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036671">
        <property type="entry name" value="DPH_MB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21454:SF46">
        <property type="entry name" value="DIPHTHAMIDE BIOSYNTHESIS PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21454">
        <property type="entry name" value="DPH3 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05207">
        <property type="entry name" value="Zn_ribbon_CSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144217">
        <property type="entry name" value="CSL zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51074">
        <property type="entry name" value="DPH_MB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="J" evidence="12">
        <location>
            <begin position="5"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="DPH-type MB" evidence="13">
        <location>
            <begin position="103"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1896201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="170" mass="18612" checksum="343FBBDF1B89CCC0" modified="2025-10-08" version="1">MGEPTYYEILGISQSLLSSQEDISCILKRAYHRALLQNHPDKVTSSASASASPSTSTPVKLFTIDEISTAYKQLSTSSLKVAYDKALLTAPTSRPQRRDSFQTAETVDLDDLAFDTATETWSLSCRCGNDRGFSFGEKDLEDAGDSGELLVGCLDCSLWLKVHFVVVEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8G8</accession>
    <name>A0ABR3Z8G8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Serine aminopeptidase S33 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000053">
        <property type="protein sequence ID" value="KAL1896904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050228">
        <property type="entry name" value="Carboxylesterase_BioH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194">
        <property type="entry name" value="HYDROLASE ALPHA/BETA FOLD FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194:SF2">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN LPX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="1">
        <location>
            <begin position="91"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="398" mass="43550" checksum="2810D4BB41F47E75" modified="2025-10-08" version="1">MSSRILDGADGRSGTVLVIATIALATVAHRILTPKKPQILPSPLKTVLPYLSPEELAKLDYKPDTLPGARDVDTPHGSIRVYEWGPEDGPRVMFIHGISTPCIILSKVAQKFVDRGYRVMLFDLFGRGYSDGVGDFPHDAALYITQAMYALTSSPVSWTGAQKLRVVGYSLGGGIAVNFAAVFPELVKSLVLFAPAGMIRPASFGVQRHIFTSGFIPETLLAYLTSLRLQTPISAKKKNNQAIAAEENAKGKADADETESSRVTDSFVDIAAAEIQPVAGEEDTPLEVRMRRYVPWMVKNHVGFVPAFMSCVRSAPLTDQAEVYAKIAKRPKNSTLVLLAKDDEIILEDEFRADTVHIMGGEDHVKIKQLPGGHDFVITQESLVVQTVLDEWEEGNFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9D5</accession>
    <name>A0ABR3Z9D5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_002718</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000055">
        <property type="protein sequence ID" value="KAL1896696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051788">
        <property type="entry name" value="MFS_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514:SF3">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="391"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="422"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="64"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1896696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="507" mass="55733" checksum="73EDABD689DD2914" modified="2025-10-08" version="1">MSVSDVNIAPRVQLSSPSQDTDIFDEKSKDHIDLEAPAATVASGEDSDQLDLQHWNAPRINIFRTGSVIFSFFLAGMSDGSIGALLPYIEQHYNISYTVVSILFLSPCLGYLLAGLVNNAVHYYMGQFGIAFLGPLLHAIGFLIIIFHPPYPVLPVAVFLVGLGSGLLDSAWNAWVGNMYYSTELLGIIHAAYGLGGTIGPLIATAMVAKAHLQWWCYFYMMLAFSIAEVAVSSWAFWGQNGLIHRVSLQAFNDGRRTTTREILRQPYTWLLSIFLLGYVGVEISLGGWVTTFMIEVRHAEPFLAGITTTLYWLGITLGRLILGFVTSRIGEKLAITIYLSLCISLEVMYWLVPSIPASIAFVILMGFFLGPLFPAAVVATTKLLTKDYHVGTIGIASAAGGCGGALLPFAVGALAQSRGVTVLQVTVLIILVLITCIWVCIPGGFHKGGLEEARDNQLVPGRELVKLYRWAEGKICRKKESELVIARRGEGIVKKRWWKTRKYFWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9Y1</accession>
    <name>A0ABR3Z9Y1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA damage-binding protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_002612</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DDB1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000053">
        <property type="protein sequence ID" value="KAL1896891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058543">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23726">
        <property type="entry name" value="Beta-prop_RSE1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="6">
        <location>
            <begin position="12"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="7">
        <location>
            <begin position="439"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="5">
        <location>
            <begin position="804"/>
            <end position="1129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1896891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1161" mass="128539" checksum="1D8D68E7DDD99A13" modified="2025-10-08" version="1">MAYFAPIHRPTSVRHSLTARFTSETEDDLIIAITNRLEVWRVTYDGAVFLHSRAINGTISTLSKLRPKDARRDMLFIGTDMNSYITVWWDDATKQIETPEVTQENFPDFVRASESTDRALVDQDGKFIAMLLWEGVISISRMEDRPKARKGPKSLRFLGQSRISELYVKSACFLPSITGPRIAFLHQKQHDWEEAQISIYPITSDDKHSEPSDFSPKVREHMFTPKDHLTSILIPIPSEFDENNRYHVRRATAAASRAYLGGLVAVGETTVIYMDGLNFEQVQAFLPEATLFTTWVQVDNRTYILGDDYGYLHVLRLVTEGTWVTRIEVAKFNQQISRASTLSYLGNGLLYLGSHYADSQLLRLDFNKLELEVLTAPNSFANNAPILDFALMDMGIRGRENAHRPDFSTGQARIVAGSGIWSDGSLRSIRSGVGADIVGVLDDFKDVSKMFALRFEGAEKVNMVAVSSLTDTRVFEFGIDGSIEELDFLPFLDFSQSSLVIRDVRGNQTLQVTASSATLRHKSSGKITKSWGPGGGSLISNASANDSYALIVVDGTKLISLDLNNQLAVAAKEAEPSSDGIEDEVTCVSTSHSFPSIGVVALWKSGTISLVNLTTMRISATFTIPKSEDSIAVPRDAALVQIHKENEGNPSLIVAMDDGMAVVFSILLADYSVSSMITVVLGSREGQLYVLPREEDGTNRVLVASDLPSLIYSETPSKYIFSATTFEDVTSIVSFDSDAFPGSLIIAANGQLLIGTIDDQRRTHVKTLPLKKTVRRLAYLPSQQAFILACLSKRLVNNEEVVESSLQLVDEIMFRPLGDPLLLEHKSHSQIPESLDILEFYDSIDGKVERLVVGTSYIESGSIETEASGTLTVFGIDEKKNVFPLVTWQTPSAISSVKVKDNLIFVGVVSGIRVFKYTETSPATGHLEKVASKSSILSPTSLDVCGDIVGVSDLTKSAFFFRFNTEKSEAFELIGQHRLNLWPTALACVAPHTWLQADSQGNVIVFNIEKQEKQKNIAERLALPTVEYISAVNIGEQVNTLRPLDITPEAGKLLGSQAIMTTAEGGVYLFGILAPEYRESLIHLQERITQHIKTLGDLSFAEYRAFRDAIYAEKEPQSFVVGEQLERFLEMSETMQEVVCEGLPISVANARNVIRRLKYMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA06</accession>
    <name>A0ABR3ZA06_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein BCP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">BCP1</name>
        <name evidence="5" type="ORF">Cpir12675_002690</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 3">Involved in nuclear export, actin cytoskeleton organization and vesicular transport.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the BCP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000055">
        <property type="protein sequence ID" value="KAL1896668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025602">
        <property type="entry name" value="BCP1_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13261">
        <property type="entry name" value="BRCA2 AND CDKN1A INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13261:SF0">
        <property type="entry name" value="BRCA2 AND CDKN1A-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13862">
        <property type="entry name" value="BCCIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028983">
        <property type="entry name" value="BCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR028983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1896668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="291" mass="32077" checksum="D43C7740E3C3CBD8" modified="2025-10-08" version="1">MGKKRSHEASSKDEPIASHDTKMKENDESSDDEDFDIVNVDFEWFNFDSEIDYHGTKSLLRQLFDVDAVLQDISGLAEMILTQNTIGSTVKVDGKSTDPYAMMTALNAHEHAAKVPMASLVAYLSEKASGNAALAPVVSLLGPTSGAQVAIVFSERLVNMPAEIAPPMYSMLIDEVEAAVEDGEPYKFTHYLVVSKVYSEVESTLVEVERKKKKAKEDAGAFFFFHPEDEVLQKHALAHGSFNFTKEEDSVADSKRAFQEMGIKMRGHMILIEAAKFPGAVQAAEAYVKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAA9</accession>
    <name>A0ABR3ZAA9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002550</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000051">
        <property type="protein sequence ID" value="KAL1896970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045831498" evidence="2">
        <location>
            <begin position="20"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="156" mass="16837" checksum="B9F31FAC0E8161BC" modified="2025-10-08" version="1">MRFYSFLPLGLLLLPFGSCRPDLTEDLQPTHTAGIEIAQAVDEDTIYNTITPSSFITSTLMTAPAPTGSGVPIDYQATNVGYNLTIAALSTGTSVILTTDPTSTESISVTVRPKHPEAEVNGLDYYVDWSDSDSDLEDDYYEDGDEEDGDEAAPCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAY2</accession>
    <name>A0ABR3ZAY2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">STAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_002696</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000055">
        <property type="protein sequence ID" value="KAL1896674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="325"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="412"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="451"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="491"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="547"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="7">
        <location>
            <begin position="604"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="92"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="42"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1896674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="748" mass="81775" checksum="63610C78A4674B54" modified="2025-10-08" version="1">MAGASRNEAEMAPSSSSYTAPLGLDRRPRDAPSETTHLLDKTNISNAAQNGPLQSSAHGTFSSQRSGSPFSLMSERQSLFYHDRDNNAVDPNGSVLNYVVDGDNPDADPARGKGPNGNSGEPQPPKEKLMMYLQYYVPCTSWLRQYKVSYISGDLTAALTMATIYIPMALSLASNLAHLPPINGLYSLFFAPMIYALLGSSPHMVVGPEAAGSLLVGTVVKASIDGSPGNEDNDMLHAQIAGVVVGMAATTVLIAGLARIGFLDSVLSRPFLRGFISAVGFVIAVDQLIPELGLAARAKQTGASHGSSWDKIVFVMENLHRMHRMTAIVALSSFVAIMFFRTLKHHLQPRQPWAAYFPDRLLVVVLFSVLCARLDWDQHGVEILGPVEAVSGHLFTFNWPFQSSMIKHIRNGMSTSFLIALLGFFESSVAARGLGGSPEFPTIELSANRELVALGMANLVASCFMCLPAFGGYGRSKVNKSTGGRSPMSSVFLSLLTLGSIKWMLPYFYYIPKPVLSSMISVVAWSLIEEAPHDISFFLRIQGWTELALMATIFFSTIFFSLTFGIAIGIGLSLLQVIRHSTRPRIQILGRVPETNRFDNAELHPERLEFFEGCLIVKIPEPLTFANTGQLRSRLRRLERYGAMVHPARPATRARDSNRNIIFDIHGVTSLDGSGTQVLEEIVRNYCDQGVRVFFSRCPGIGHPVRDMMERSGIVNMVGEQRLTADVYEAVRRTERAESEAAVASSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB53</accession>
    <name>A0ABR3ZB53_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Bifunctional purine biosynthesis protein PurH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">HGT20</name>
        <name evidence="10" type="ORF">Cpir12675_002374</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000046">
        <property type="protein sequence ID" value="KAL1897270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045263">
        <property type="entry name" value="GLUT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503:SF8">
        <property type="entry name" value="FACILITATED GLUCOSE TRANSPORTER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="319"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="348"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="448"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="480"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="18"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1897270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="520" mass="54901" checksum="FDA9117931D00888" modified="2025-10-08" version="1">MATSPSRLGGASVYLIIIVFLAALGPLQFGFHIPSANLHQAELNAPQDVITCKSKPVAALVSKVNRWFSRSSDSTANNSNVLLPDCVPMSEAAFATISSILTIGGLTGALAAGPLTSKFGRRLAMRITGICFLIGAVFETFASGVGMLVIGRFIVGLGAGASTVIVPLYVSEVAPPASRGLFGTSTQVMINVGILVTQIEGYFFSYGNAWRWILGSGVILGFVHIFGLSVVPESPAWLASQGRFDAARRNLQRIRGGPLADISDEVAAWKDYDAAADINAEQEGLLSIPMASSNSGSNTDAAHLGFLEVLQDPDAFRGIVACVGIATGQQLCGINSIIMYSVSLLNDMLPMSSALLSIIISLVNLGTTVACSPLPDKLGRRKCLLLSIAGQGTSSILLAFSIQMGMKYLSAFAVLGFVGFFAVGLGPVPFIMAPELVNQEAVGAAQSWALGSNYISTFLIAQFFPIANSFLNDLLGGAGWIYYVFGGLSVLVFLFVLSYVPETKGKRNADEVWGRTRRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB54</accession>
    <name>A0ABR3ZB54_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Cysteine dioxygenase</fullName>
            <ecNumber evidence="2 7">1.13.11.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_002305</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-cysteine + O2 = 3-sulfino-L-alanine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20441"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:61085"/>
            <dbReference type="EC" id="1.13.11.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="7">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the cysteine dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.20" evidence="2 7"/>
    <dbReference type="EMBL" id="JAWDJO010000044">
        <property type="protein sequence ID" value="KAL1897517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10548">
        <property type="entry name" value="cupin_CDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010300">
        <property type="entry name" value="CDO_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12918">
        <property type="entry name" value="CYSTEINE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12918:SF1">
        <property type="entry name" value="CYSTEINE DIOXYGENASE TYPE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05995">
        <property type="entry name" value="CDO_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="216" mass="23710" checksum="FCB436E2CED348C5" modified="2025-10-08" version="1">MGINVVSPNIEHVSVTPCGEHSDNKFQKLVQEIKAVLGPSSGLTCDDIDLEGLTNLMRSYDSKVEEWQEYFIGDEKMGYTRNLVDEGNGKSNLLVLVWSPGKGSAIHDHGNAHCLMKILSGDLTETRFAFPENNNGGPMKVLSEKVYSENAVAYMADELGVHCIRNNGTKFAVSLHLYTPPNVAKSGCNIFDKETGESSHISKCGYHSVFGRILKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBH5</accession>
    <name>A0ABR3ZBH5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histone deacetylase</fullName>
            <ecNumber evidence="2">3.5.1.98</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RPD3</name>
        <name evidence="7" type="ORF">Cpir12675_002108</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histone deacetylase family. HD type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000038">
        <property type="protein sequence ID" value="KAL1898021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141221">
        <property type="term" value="F:histone deacetylase activity, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd10004">
        <property type="entry name" value="RPD3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003084">
        <property type="entry name" value="HDAC_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF10">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01271">
        <property type="entry name" value="HISDACETLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="6">
        <location>
            <begin position="47"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="392"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="424"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="445"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="494"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="510"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="540"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="607"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="662"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="745"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="762"/>
            <end position="772"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="780" mass="85956" checksum="842455065CF6E32A" modified="2025-10-08" version="1">MSGSGASGSISETLGGQLTSIALNQTPKKVAYFYDSDIGNYAYVTGHPMKPHRIRLAHSLIMHYELYKYMEIYRAKPATRGEMTQFHTDEYIDFLQKVTPDNMDAFQKEQGKYNVGDDCPVFDGLFEFCGISAGGSMEGAARLNRQKCDVAVNWAGGLHHAKKSEASGFCYVNDIVLGILELLRFKKRVLYIDIDVHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGELRDIGIGQGKHYAVNFPLRDGINDVTYKSVFEPVISHVMEFFQPEAVVLQCGGDSLSGDRLGCFNLSMRGHANCVNFVKSFNKPTMMLGGGGYTMRNVARTWAFETGVMVGKEMNNTMPYNEYYEYYGPDYELDVRPSNMDNANSPEYLDKIKAAVIDNLRHTAPAPSVQMQDVPRQPLGGMTDEEEAELDDLNEDLHKDSRMTQREWEKKVANEAELEPDSEDEEMAHSIGGPRPTAPKRTFNDYRNDEMEVDSGNATPANGLDGDKSPKKASLETTEISNEDVDMDREVPEEPSTNEKGSKVSSPTKEPAGKEESPKESRKQEERLPEPEKSHIPEKSTEVSNEKLVVDADGDIGMADTEAPEVKKEEIEPAVITETETNKPNSGDVTAAKTSTAETVVVKSATEDASTEVAAKEPANPVPEVAKEPGSVAEEKASAEQVTKEPESETKKPWVSEETTKEKDGVEKESRKENEEKKEEAKLSTVEKKEATPQPEATPKASETAAELVTGTESAAESKEALSASAEDKEKPATSQETTNASTAADKDQEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBQ2</accession>
    <name>A0ABR3ZBQ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetylglucosamine-induced protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000036">
        <property type="protein sequence ID" value="KAL1898103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022036">
        <property type="entry name" value="DUF3605"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35020">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-INDUCED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35020:SF4">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-INDUCED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12239">
        <property type="entry name" value="DUF3605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1898103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="225" mass="25625" checksum="7D1B88D745C6CFCC" modified="2025-10-08" version="1">MPSTKPDPTAWWNINIPTTEHTVAVPIDLAGCSERDTALIGVDESSYTPLSWEQCRAIVATNDLEAFSRSPLELRRYRRAMYALAVTHGSVASFLANERIGWGEGEIKPHGTIPFETPEDYKIVYNDWPYGLDPRIVHLVVWTKFQLVENPATGRLTALSAQQIDGFVERTFCSRVPAENVIWFKNWSAIKSVQALEHFHVLMFEPDADFIWEITNGDRPLCERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBT6</accession>
    <name>A0ABR3ZBT6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ADIPOR-like receptor IZH2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_002555</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ADIPOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000051">
        <property type="protein sequence ID" value="KAL1896974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004254">
        <property type="entry name" value="AdipoR/HlyIII-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855:SF52">
        <property type="entry name" value="ADIPONECTIN RECEPTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855">
        <property type="entry name" value="ADIPOR/PROGESTIN RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03006">
        <property type="entry name" value="HlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="308" mass="34395" checksum="CD6DFFA65798379A" modified="2025-10-08" version="1">MLRDRYKKPPASAVHAKLQTGSVSSLASSLLIHWDDLPAWRRDNAFIHTGYRATSNSFYASFCSLAYLHNESVNIWSHLLGSVGFVLTALYLYAVIAPRYESASPADIAVFAAFLGGAVLCLGMSATYHALSNHSNSVAKWGNKLDYTGIVFLIVGSYVPALYYGFYCDIILRELYTTLICMLGFGCVLVSWIERFRTPEWRPYRALMFVALGTSGIVPILQGLEKYGWTHLEQRMSLSLVILHGAMYVIGAVIYAARWPERLWPGAFDHFGSSHQIFHGFVLVAALTHMYAMALAFDYHHTVVGRVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCG8</accession>
    <name>A0ABR3ZCG8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tryptophan--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Tryptophanyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">WRS1</name>
        <name evidence="11" type="ORF">Cpir12675_002471</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000048">
        <property type="protein sequence ID" value="KAL1897214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00806">
        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.240.10">
        <property type="entry name" value="Tyrosyl-Transfer RNA Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10055:SF1">
        <property type="entry name" value="TRYPTOPHAN--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10055">
        <property type="entry name" value="TRYPTOPHANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="443"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="470"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1897214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="494" mass="55503" checksum="77B1D9AC8AB08856" modified="2025-10-08" version="1">MASPTILEPTPVTEGIATSDAPPSAAKQNVNPWSVSGEIGEDGKVKAIDYRKLTEEFGTTLIDDALLARFEHVTGHKPHRFMRRQIVFSHRDMSLILDRFEKNEPFFLYTGRGPSSDSMHVGHVQVFQFVKWLQDVLDVPLIIMMTDDEKFLFSEKRTVEEVMGYTRKNVRDIISVGFDINKTFIFSDYDYMGGAFYRNITRFAKLVSLNTACKVFGFDESSNIGKIHFGSIQGATSFASSFPHIFGDDESKSNSIPCLIPCAIDQDPYFRVTRDVAARLHYSKPALIHMRFLDALQGPGSKMSASDDTSAIFLTDTTKQIKNKINKYAFSGGQVSVEEHRQKGGNADIDVSYQYLLFFLEDDEELKRIKEEYESGRMLTGELKAICIKFLQDYVQEFQTRRAQVTEEVVSTFMAPRPLQWGGNPKVPRADLVVPVVASSISTTPTAGENTEGGDGKMTKNQLKKLQKLKQQEEKKAAKAKEKAEKTANVVSEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD39</accession>
    <name>A0ABR3ZD39_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phospholipid/glycerol acyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_002232</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000041">
        <property type="protein sequence ID" value="KAL1897733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07990">
        <property type="entry name" value="LPLAT_LCLAT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032098">
        <property type="entry name" value="Acyltransf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10983">
        <property type="entry name" value="1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10983:SF16">
        <property type="entry name" value="LYSOCARDIOLIPIN ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16076">
        <property type="entry name" value="Acyltransf_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="5">
        <location>
            <begin position="116"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1897733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="390" mass="45507" checksum="117DBC213405B479" modified="2025-10-08" version="1">MNALLKGAAMDVHPGGKVKHGPLMQVARGVVLALYFLVGCLAILATQVLGSPLYWINRPLYYSYIALTKQSFALLAITVTQWWGPTTIRISGDDSVANQMRRTQDGRVEFDFPERLVLIANHQIYTDWLYLWWVGYANKLQMHGHIYIILKESLKMVPILGQGMQLYRFIFMSRKMSIDQPRLAYRLDKLKERHVAPNGTEYMNPMWLLLFPEGTNISPNSRPRSQKWADKMDIKNPEHMLLPRSTGTYFCLKQLDDSVEYLYDCTVAYEGIPRGGYGEDYFTLQSTYFQGRPPKSVNFHWRRFRIADVPLDTCEEFDRWLRERWYEKDALMETYLATGRFPTSELAKKDYIETAVRTKYPFEFLEVYNVLGGILGVTHFARRMVRTLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDA4</accession>
    <name>A0ABR3ZDA4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_001773</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome b5 family. MAPR subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000030">
        <property type="protein sequence ID" value="KAL1898666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050577">
        <property type="entry name" value="MAPR/NEUFC/NENF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281:SF76">
        <property type="entry name" value="CALCUTTA CUP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281">
        <property type="entry name" value="MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="3">
        <location>
            <begin position="101"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="262" mass="29587" checksum="4E3C6AFD50AD5E68" modified="2025-10-08" version="1">MADQEIRQRKPAVSEKEPLLQENSIPAKPKSSHQRIRDEDEASASSLVLDIFRVLTFLLLASCGLSYVTSGGKSMFWSTQARPNYLTLNYWKAHMSGPIYLTPEELTAYNGVDESKPLYIAINGTIYDVTPGRRVYGPGGSYKYFAGVDAARAYVTGCFAEDRTADMRGVDEMFIPLDDPEIDSLYSPEELTALRAKEREDALEQVNKALLHWVNFYAKSDKYSKVGYVRRAENWLEKEEPRALCASAQKKRPKRKAPGKQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDJ5</accession>
    <name>A0ABR3ZDJ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000030">
        <property type="protein sequence ID" value="KAL1898713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045439146" evidence="1">
        <location>
            <begin position="16"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="210" mass="22913" checksum="8DDE5410CB53F1FD" modified="2025-10-08" version="1">MKFLSLLAAAALASAQTSDYFMRLIGGNAVTNNAFLHRNWTANISPIAVPAPLNLNDHYYRVRPSPALDSANQLGAPLLTNGKLTVIPTQPHPGPLASYLSLSRNENIADMLRMTTSVYPASNNMVFDGWTAVRDAQGRALLRYSDPASQSRWVAVKTNTTQGYEGWAPWWVAPNAENMAVLEEWDWVLVDIELVPATGLVNSSAPFGTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE22</accession>
    <name>A0ABR3ZE22_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein-lysine N-methyltransferase efm5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">EFM5_1</name>
        <name evidence="2" type="ORF">Cpir12675_001859</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000031">
        <property type="protein sequence ID" value="KAL1898655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05271">
        <property type="entry name" value="NDUFA9_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051207">
        <property type="entry name" value="ComplexI_NDUFA9_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126:SF11">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="1">
        <location>
            <begin position="50"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="375" mass="42832" checksum="028E476D2EA7BE32" modified="2025-10-08" version="1">MSGLRATMQSSRDATFKMLGRRSISDIAITRTGKPILRTPGGRSSLGGNTATVFGATGRLGRYIVNRLARQGCTVIVPFREEMAKRHLKVAGDLGRVIFMEYDLRNTRSIEESVRHSDIVFNLIGRDYPTKNFSLEDVHVEGTERISEAVAKYDVDRFVHVSSYNADPKSDCEFFETKGRSEKVAREIYPETTLVRPAPTFGFEDNLLVKLATITNLLTCNNMKERYWPVHVIDVGRALELMAFDDSTAGQTYELYGPKNYSTAEIAAMVDREIFKKRRHINVPPKILKPLADILHKLVYWQTVSAQQFEREMYDQVINPAAKTFEDLGMTPSDISEFTYHYLQGFRSSAYYDLPPATEKEKREERKYLHVIDNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZED2</accession>
    <name>A0ABR3ZED2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GDP/GTP exchange factor for ARF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">GEA2</name>
        <name evidence="3" type="ORF">Cpir12675_001673</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000027">
        <property type="protein sequence ID" value="KAL1899013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00171">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056604">
        <property type="entry name" value="GBF1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032691">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HUS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF388">
        <property type="entry name" value="GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12783">
        <property type="entry name" value="Sec7-like_HUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23325">
        <property type="entry name" value="TPR_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEC7" evidence="2">
        <location>
            <begin position="625"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="500"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1297"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1496"/>
            <end position="1520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="517"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1297"/>
            <end position="1311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1496"/>
            <end position="1510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1511"/>
            <end position="1520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1520" mass="169305" checksum="34084EDD2972774C" modified="2025-10-08" version="1">MQYRNHPVSVAVDPVSLVISECISITSEIRKRAPLHNFSVSAILGGSPNPVHLVPPSPRGAAFNSTSTSRVDDDVASGNRWGLRATNAKSTQDHPLMSSFGRLRHELSGTKDICSFDALSLLKPFLQIMQTKGTAAPITILALGALRKFLAYGFIGTHSPRFPLAMQSLSSALTHCQFNDSGQMEVVLLMILNLMEDMMSGPGGHILSDDSVCKMMQRGLVICSSPRFSPVLRQTAEATLIRMCQIIFQDLKFLESESQLQSVSLDDDPNLDITLMRPPLPIASEKPQDDPLNGQKEDLVVNEDLVDDNTIKTSTPDTPLLSEAQEDDDTSHKTVRNSTSSSRQDEDEEMEMEPLDLRPYSLASVKEVLRVLVSFLDPNDLQYTATMRIMALRIIHVALEVAGSSLARHPSLAAIVSDSLCCHLFQLVRSDNMDLLQESLAVAGTLLETCRDILKLQQEFFISFLITSLFTPADVPRELNIDPSLYDGIPKTLKLVKPAPAAPTTKAASGRSTPVSGKDRSKSSFELAARKPDARQAMVECVGVLSRMPTFMIELFVNYDCDEDRADLCEDLVGLLSRNALPDSATWSTTSVPPLCLDALLRFVQFLAERLDDEHKTDGLPDAESLKRRRQRKLVISKGAAIFNDKPKDGLAYLEAQGIIEDASNPVSVASFLQSTTKINKAVLGDFISKRGNESILDAFLNAFDFSGKTLDEALRMMLETFRLPGEAPLIERIVSLFSEKYFESYTDNDIAHKDSVFILTYAVIILNTDQHNPNLKHQKRMTYEDFSRNLRGQNNGQEFLPEFLQRIFDSIRSNEIILPDEHDNQHAFNYAWRELLSKAGSESELLVCDTNIYDSELFATTWKPIVSTLAYVFMSATDDAVFARVVTGFHECARIAAKYGNTEALDQIVYCLCQMSTLAEKLPHNTALNTEVQVGDSSVMVSELAVKLGRDFRAQLASLVLFRVMNGHEALVQRGWSYIIQIWLNLFINSLIPSFATLSNVEKPTFPEIPLQTPSQVIDRATKVNDSGFFSAFTSYISSYAADDPPEPSDEELESTLCTIDCVKQCNMQDIFTNILNMDPNALAKFIDMLLRHLPEGSPAVINVMADQPPASPVNGQNSTSFEPVYDPSIPYILELCTIFVLKDDETVRILGRPVADSLFSILRDAKSYHSIVVSRCALHLFEVLRASYQNGFINVPVLLHTIANFPKDVMAKCSNLLLKGLRECIQEPSPLRSEIMTSPDFWAILRLLSGRPDCSSIVFEILDAGTTGDPPSIISDNYEAAIKLLNDFATASRLSTSPRQDIKQRPSSQRSKKTCETDEVVSRGMRAVTLIYNMTGRIPHLMKQSHLESNEDTNHKEWTAIFSEVLFPLIHRLLKPEVFSSDREGMGEMRVQTASLLCKVFLQYLVILSSWDGMFDLWIKIIDIMDRLLNSGQGDVLEEAVRENLKNVVLFMSSIDYLVPPSKDNSKAELWHETWKRIDRFLPDLKIDLALEADDKGSASSEKQKQDAIEDVVTEGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEP5</accession>
    <name>A0ABR3ZEP5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin-conjugating enzyme E2 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">E2 ubiquitin-conjugating enzyme 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Ubiquitin carrier protein UBC2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Ubiquitin-protein ligase UBC2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">UBC12</name>
        <name evidence="11" type="ORF">Cpir12675_001769</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000030">
        <property type="protein sequence ID" value="KAL1898662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23794">
        <property type="entry name" value="UBCc_UBE2F_UBE2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="10">
        <location>
            <begin position="29"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="7">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00039884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00041569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1898662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="183" mass="20846" checksum="700D2D180F09118C" modified="2025-10-08" version="1">MLKIWSMKKQQQDAENADTAAGKKKKVTAAQLRVQKDLSELDLGGTMSTEFSDPDNILNFILTIEPDEGMYRGGRFTFTFDINQNFPHEPPKVRCRETIYHPNIDLEGKVCLNILREDWKPVLNLNAVIVGLQFLFLEPNASDPLNKEAANDLRASRETFKRNVWLSMTGTSIRGTLYDKVLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF75</accession>
    <name>A0ABR3ZF75_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SHSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_001586</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000026">
        <property type="protein sequence ID" value="KAL1899030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06464">
        <property type="entry name" value="ACD_sHsps-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00298">
        <property type="entry name" value="ACD_sHsps_p23-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031107">
        <property type="entry name" value="Small_HSP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11527">
        <property type="entry name" value="HEAT-SHOCK PROTEIN 20 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="5">
        <location>
            <begin position="66"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="120"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="287" mass="31852" checksum="A4A25CDA1528C74F" modified="2025-10-08" version="1">MAFFAPHFATSDGFSPFFSIINDFDGPTFQSKPVNASPATHPLAAYMTPSCPKRTSEPNSQRTSRRSLPTFKPNFDVRETADAYELHGELAGLKKKDVSIEFTDAQTLVVHGRVERVYTKFPPSKTRAQHEPKQAESAPSTERDGADMDVDSTPKDGAEKPKSYNAEPTAPQSPKPQKATVEDTVDEDDRFSVTSMSSTHSANPSYAEASVADIKKSIVQAPTEVTRKPESDEATYWVQERTVGEFSRTFSFPRLIRQDEVHASLEDGILTVVIPKAHNENRRIVIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGQ1</accession>
    <name>A0ABR3ZGQ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">S-methyl-5'-thioadenosine phosphorylase</fullName>
            <ecNumber evidence="4">2.4.2.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">5'-methylthioadenosine phosphorylase</fullName>
            <shortName evidence="4">MTA phosphorylase</shortName>
            <shortName evidence="4">MTAP</shortName>
            <shortName evidence="4">MTAPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MEU1</name>
        <name evidence="6" type="ORF">Cpir12675_001483</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>S-methyl-5'-thioadenosine + phosphate = 5-(methylsulfanyl)-alpha-D-ribose 1-phosphate + adenine</text>
            <dbReference type="Rhea" id="RHEA:11852"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58533"/>
            <dbReference type="EC" id="2.4.2.28"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; S-methyl-5-thio-alpha-D-ribose 1-phosphate from S-methyl-5'-thioadenosine (phosphorylase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.28" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000023">
        <property type="protein sequence ID" value="KAL1899367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017061">
        <property type="term" value="F:S-methyl-5-thioadenosine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd09010">
        <property type="entry name" value="MTAP_SsMTAPII_like_MTIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01963">
        <property type="entry name" value="MTAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010044">
        <property type="entry name" value="MTAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018099">
        <property type="entry name" value="Purine_phosphorylase-2_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01694">
        <property type="entry name" value="MTAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42679">
        <property type="entry name" value="S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42679:SF2">
        <property type="entry name" value="S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01240">
        <property type="entry name" value="PNP_MTAP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 4 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3 4" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleoside phosphorylase" evidence="5">
        <location>
            <begin position="12"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="61"/>
            <end position="62"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="94"/>
            <end position="95"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="220"/>
            <end position="222"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="4">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="4">
        <location>
            <position position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="307" mass="33251" checksum="3F3590C58544AD54" modified="2025-10-08" version="1">MSLPTTFDRPVRIAVIGGTGLSKIEGFEAVASVTPQTPWGTPSSAIQICLHNNVPVAFLARHGEHHQYAPHEVPARANIAALRHLGVRSIIAFSAVGSLQEEIKPMDFCVPDQIIDRTKGIRPFTFFEGGVVGHVGFADPFDHQLAEVVKECASAMDGDGVMMHSSGTIVCMEGPAFSTRAESNMYRAWGGSVINMSALPEAKLAREAEIAYQMICMATDYDCWHSTEDVNVEMVIKCMTHNGVNARNLIGAVLNKLTAQADGDVVMAKKWEGSVVGAIQFMTKPAGRNPTAMKNIEFLFPNIFESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGW6</accession>
    <name>A0ABR3ZGW6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Extracellular serine-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001594</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000026">
        <property type="protein sequence ID" value="KAL1899038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052953">
        <property type="entry name" value="Ser-rich/MCO-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883:SF15">
        <property type="entry name" value="EXTRACELLULAR SERINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883">
        <property type="entry name" value="SERINE-RICH PROTEIN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046894630" description="Extracellular serine-rich protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="164" mass="17501" checksum="6A4221254358ED49" modified="2025-10-08" version="1">MRFAVTALLAATVVMAAPTSESSSENDSSQTRTVWIGGRSKVSPATLRANVGDKIEFHFLSGLHSVVEANYFDPCQHNGGFASGYFSTIERDHQNSQTFVITIEDNSPIWYFDGAGTECMSGAVGVINPPNDGSRTLSGFKRAAKVESSSNSPSQFQGGSVIKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIC9</accession>
    <name>A0ABR3ZIC9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000993</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000013">
        <property type="protein sequence ID" value="KAL1900411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="155" mass="16552" checksum="2F5C38F1DB3B6965" modified="2025-10-08" version="1">MMHPAEPASSNSVSTTAGVTCPSQYGMGGSFQASDNNSVEFPALTFTSCQALGENISISGPVVAEPQPQSSRQKDESSNSGEPVSAVVDQLAAQFPKVETVDIDGSVNRPFKKLYRELDAGKSPGEAKRSMNALLLYRKAYQELSRAINGQKDHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIG6</accession>
    <name>A0ABR3ZIG6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">CAP-Gly domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Cpir12675_001160</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cell cortex</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
            <location evidence="1">Centriole</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the dynactin 150 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000017">
        <property type="protein sequence ID" value="KAL1899939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022157">
        <property type="entry name" value="Dynactin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916">
        <property type="entry name" value="DYNACTIN 1-RELATED MICROTUBULE-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916:SF6">
        <property type="entry name" value="DYNACTIN SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12455">
        <property type="entry name" value="Dynactin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00845">
        <property type="entry name" value="CAP_GLY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0132">Cell division</keyword>
    <keyword evidence="10 13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-0243">Dynein</keyword>
    <keyword evidence="7" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8" id="KW-0498">Mitosis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CAP-Gly" evidence="15">
        <location>
            <begin position="23"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="75"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="298"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="743"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="323"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="1085"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="121"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="147"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="199"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="275"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="743"/>
            <end position="752"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1899939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1387" mass="153377" checksum="3321FE5F12C8B229" modified="2025-10-08" version="1">MEVVPGQIVRLVDGRIAEVKFAGETSFAAGVWVGVELEDATGKNDGSVQGERYFECAMGKGMFLRPTALTIIRQAPAPPKPSAPAPGRRASSRPNSLLGGPRTALSDGPAPGKRMSLSAPSPSPGPKPSRPPSRPSSIVPGTRPKESLQSPTKSPTKQLSVSSVSTRTNTPANSRTVSGAATKRPPGSRTSMGPPPAPTSKTRQSSVSSNSARPGIPSRNSSGNRLSISNPSKILTPKPSEGLRRRSIEVHNDLQHEARQSPISPLKSADGILSPQPQSPVLSRTNVLEKLTVVSTDGSSGAVSPKFVPINRPDGPRGTSGAATATAREIDDLKAKIRVLDRKRSEDREKIKALEMVQQERDKFEGIIQKLQTKYHPQQQELTELRKQLKEAEAHFESIEALQEDRDLALESATLDREMAEEQYENCRAELAEVKMRLEELELEVEILREENGELSKDISAEDRTSAGWVQLEKNNERLREALIRLRDLTQQNEDDLKAQVQGMEEDLKDYTIIREQHIMDKEKLEKANNAIEDLRQQLDNALGAEDMIEELSERNMTQAEEINELKAVIEDLESLKEISDELELNHVHNEREMQVELDFKDAVIAEQGRRANQREETITDMEYTLSKFRSLVTTLQSDLEDIRASHAVTETESEELSTKSRAMIDLNMKLQLSAAKTQAKTIDLELRRLDAQEASDHLEIVKLFLPDSFREDQNSVLSLLRFRRVSFKATLLRGFIKDRINNTNNTNAAPNDGSDESNKSVGHEDDTFAGCDVVDKLSWVAAMCDRFASSMAHCSIDDFGRFGGAVHELEPVERALNQWTDGLRRDELKEKNCATELQRTIALLTHLAEVHLPQDDLPSYADKAHMQTTVVVSQLESSATALQAIKTLVQHVVPSTTQITTPATEEGGESTVIVENDAMAEHFARRIDSAISHTRSAKVVAGKAVRALEELHSRSLTLPPNTHELFDQCQTASAELGRLSRCMGEEIHAVLSTEDDRTRPFNYDDVVQAVSKAALQVSSAAESDIFSTYLSKLRTLGSQIFELSSLCSDLTQALEFEITPEPWKLRAQELKARKVVPVDAEESLRRLREEYNEARRTVAQREDALSTAVLKIETLEARMKDAQAKVEAMAELEMQIEDENLMNASLKEDIDRQDRELKALEAERDKWKKIAGDSRAAIDGADVTGNRAGKERAVATAREMDALKTDISSLQSAVRHLRDENRRARGIDQAALSWLSEPLLPPKPAVVERTALVTAEGRDVLSELVRLAATSTVYNLQQLPRDKLAWRPAKSTPQFHAAKQAEDFAAWDSWQKAVSRKASAMATAAMAGKRNVRRRPLAALQVRLPDENGKTIPGSTANVQIVGSAEWEGLQGRVEGLLNGGRVLCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJF0</accession>
    <name>A0ABR3ZJF0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cation efflux protein cytoplasmic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_001001</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000014">
        <property type="protein sequence ID" value="KAL1900317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45820:SF5">
        <property type="entry name" value="DIFFUSION FACILITATOR FAMILY METAL ION TRANSPORTER, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45820">
        <property type="entry name" value="FI23527P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="4">
        <location>
            <begin position="12"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="156"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1900317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="165" mass="17938" checksum="58743DBF7710737D" modified="2025-10-08" version="1">MKSGRILMETAPEGMDLQDIKHDLEMIPGIKSAPELNVWRLDEEVVVASIHLVVSDLTIADFASKAKIVGECLSAYGIHSYTLQPELQSSYDDKLEISTSTAVVIPAPAVSVPPRISSTNAIIGAMHSPASSILESPKMLKVQLEDTQPTPALSRTKLEEQQKME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK76</accession>
    <name>A0ABR3ZK76_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_000931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF131">
        <property type="entry name" value="GTPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G07630)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1900461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="183" mass="19972" checksum="18137310A97D9914" modified="2025-10-08" version="1">MASDAHDISDEDMFTHTSFANMGKRLKPYNDTLALLHELGIQHELELPELVLVGDQSTGKSSLMSGLAGMSLPRSGGLEEVEEVLRWAQIAILNPDKNHEQYIPGLGHTTMNMSLNQAAECTTAKFSPNVVALELKGTDYANLSYYDLPGVFVTSTDENDMHLVKVVENLTAGYITHPGAIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLG3</accession>
    <name>A0ABR3ZLG3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001033</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000014">
        <property type="protein sequence ID" value="KAL1900349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="394" mass="42935" checksum="1BF82258EA9CCA16" modified="2025-10-08" version="1">MPTYLCHGFRWYRNNIRVFTQFQDIENAAPDWVISPGSSHAMIYRLYELFDFLPFAEDLVPATSAATAMASATSPTSPTPMAAAASSDSQPRLHKKRSRARFLNKLSILKGGGSGSSSGGGSSNSTTAAVAAPTPNDSTPSTPVAPPNVYKTGELLSKSVSANRGLLSDDEEPLPPPSQLEQPPIVPKIVLPPGSETIFLPPGVKPPAMPPPPSPLEEAKACVVHTDPDDPVLRNNDWAAICLLEEWDARADLVPTETLCSRPWAFVADYAVRIDLSGRVTDEIARYQRWCNKLAPENRPMGGGDGLASGFEDDPAADRAAIETGFTPKPAPPRNPGWFQKLRDNMEFEGAIQWYVVVCEDEMRDFPAIDEEELVERIKFDKPERPAATHQKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLV7</accession>
    <name>A0ABR3ZLV7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000603</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046774740" evidence="1">
        <location>
            <begin position="21"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="276" mass="31432" checksum="51F9542E97F129AC" modified="2025-10-08" version="1">MRFFSISLPLALSLVSLSQATILENKGYRKVSAGGVDGVLFRDPYGSYQLADAISFHPWMKMATIYIANNDMEPEHQNKLSLTEIYTALAEEHKRKPEDVDWIVTEVVGDPEMEDFILGIRKGRNVGPKDEVIITPSQHEWKKILDTKHYMYAALVNRKAIDKIIITTHQRTQPGVTFDVSSFHFYFPSWQLRNPYSNDIGSGVATQSDDNLKWAEVWKKEWKAMWKVDMTGGWKAQWSNQAEEAAMYKAIYDAEKQQEASSLAGLATQITQVMSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZML8</accession>
    <name>A0ABR3ZML8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Deacetylase sirtuin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_000538</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47651:SF17">
        <property type="entry name" value="DEACETYLASE SIRTUIN-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47651">
        <property type="entry name" value="NAD-DEPENDENT HISTONE DEACETYLASE HST4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="5">
        <location>
            <begin position="24"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1901305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="407" mass="44364" checksum="06AFCDEDF4D05CE1" modified="2025-10-08" version="1">MRPASIRIPYRDKFPSPVTLPPTATSIPGAIDALLEFLTARSPHGLPQSTVVLSGAGLSVASGLTDYRGENGTYRVNKTYRPIYYSEFVANHAARKRYWARSFLGWTTLHNAKPNAGHFAVRDLGQMGLVNAVVTQNVDSFHPLAHPQLRTMELHGYLRAVKCIACKSEFPRDSFQDDLARLNPVWAKFLREAIAEGAFSSTDILKQSEKLGAPAIRSNPDGDVEVPGAQYQTFRYPACPRCLVSPTEDAMGRKHKVEVDGDGAWIPTSTGGVLKPAVVQFGENIADHVKDTAQEYIDQAGKLLVLGTSLATYSAWRLAKSAKERGMPIAIVNIGGVRGEETFHGDLEPGQLGARGVRVELPTHVLLPQLVEKIWEEVSPGARGVASTPALNRLRTKGVGVFKEMMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN53</accession>
    <name>A0ABR3ZN53_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Serine/threonine-protein phosphatase 2A activator</fullName>
            <ecNumber evidence="10">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Phosphotyrosyl phosphatase activator</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">RRD1</name>
        <name evidence="12" type="ORF">Cpir12675_000021</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the PTPA-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="10"/>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04087">
        <property type="entry name" value="PTPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004327">
        <property type="entry name" value="Phstyr_phstse_ac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043170">
        <property type="entry name" value="PTPA_C_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037218">
        <property type="entry name" value="PTPA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10012">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10012:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 2A ACTIVATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03095">
        <property type="entry name" value="PTPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140984">
        <property type="entry name" value="PTPA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0697">Rotamase</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="255"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="527"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="591"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="606"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="636"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1902123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="649" mass="68460" checksum="D787C964B5483392" modified="2025-10-08" version="1">MYPYPTINLGPSFNQQKAIPSSTYSSLSSINSSQASSSNIDLSANFLQTLIPLSTITLSMATPPQSTALATSGLFPKLALLDLTAPPRFQHTVKRINDGADVNTFLTSLAYRDIGVWVMQLNRALCPRREAAVQPSVPSASAFAPPAVYSSSTSSTSPSSSLGPTTIPALSLKLPSAARERARTFSLQDVRNEAMLPASVQRVRKLLQRSEALLAQAPSEPGPAGAAHRFGNPAFRKWVALVKDAARDMMQQELGIGGGDAAEGGSDTGTETETESEKCTGNQLENQVVADSQPMTALDELASYFIGGWGSAERLDYGTGHELSFLAFLGGLWKLGFFADGEQDGPIERAIVFGIFEPYLVLVRKIILLYRLEPAGSHGVWGLDDHFFLPYIFGSAQLTRPIMASEPMPLEGSVRSAPRPSSITDSTAVATHAPHNMYYAAIAFIHAVKRGHFAEHSPVLYDVSGISAGWGKINKGMLKMFNAEVLAKFPVVQHFRFGTLFAWAPDPHAAPSISSVHLRNQPHHLFQKPSVKSGPAGIAVSSTTMSPPGGAGTMGPWAVGNSIGRGGANANAAASARAQSSGTAAWAEATRMPMPSGTSGGIPYSRISSGTAIPNTSPGTKIPSDGDGTGNGVGGSQPTQVSTRAPWSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN57</accession>
    <name>A0ABR3ZN57_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000019</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033481">
        <property type="entry name" value="Dni1/Fig1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12351">
        <property type="entry name" value="Fig1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="252" mass="27431" checksum="6C8307EE6EE9491B" modified="2025-10-08" version="1">MIDANPIIERFNSRVFGYILLVLVVVFHSLVIAGCMSKSSGIPGLYIVKLQISNSSSVQVRVGYFAMCVNGPLNSPYECYSTTGLGQDKLRSFFITENMDATTSSQISQLLVPARAMQTRVFPPLIAGAFGCFMASVMLAAVRQNMLAQPSPRAFWTSRHTSAIIACLGVLAFGLAAASAVMTTQVAKALAWWLNDMDPQENGIYISEGTGMQVLQWLIVSMIILYHLCFAHLFTDKTQGVEEKAEAPDAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN80</accession>
    <name>A0ABR3ZN80_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Trafficking protein particle complex subunit 2-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_000410</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006722">
        <property type="entry name" value="Sedlin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12403">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04628">
        <property type="entry name" value="Sedlin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1901541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="153" mass="16730" checksum="5BC2ACEB9E0A9CCB" modified="2025-10-08" version="1">MPIRTPLQFSLLLSSSLDIFELRAKSNTAAAVGLSGELGLLHAIDDRLAAYGFETNTGVKFVVIIDMRGRSIDSTMVSDRARSAVTVGLRDVELKPVFKAIQAAYISLLQNPFFQPDEHSPLTGQGGKRITSKKFSDTMKHIGEAWTPDVTHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN83</accession>
    <name>A0ABR3ZN83_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SP-RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000399</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782:SF4">
        <property type="entry name" value="TONALLI, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782">
        <property type="entry name" value="ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="868"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="968"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1022"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1436"/>
            <end position="1477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="319"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="868"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="887"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="975"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1022"/>
            <end position="1048"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1485" mass="163599" checksum="4FB806391D3500EB" modified="2025-10-08" version="1">MPPSSDRRKKSGAKSTNEPLKLKDRDIAESNKTVAFFLGVPRRAQPWASQSLRPASNAGSIRRRRSRGVDTQNQIDISALNTGIGNGVVVPTSESPTHAKAQTQAPMVVLDPKPYASRSPTMAGPIHSVGFRSNCSRDPTPPPEQNQQGHHAPYATRQTFTSSNAPEATATSSPTSSPVPRLTRTCSQPYTSRHTTFTITENSTDTCLAQHRHLAFNRNGNVGDKLEVLTPIHHAAENGKNNHGLESNHPSQLISHHVRNISAGDYALPRFPSGAQNTFDRDDRGSNNSSNLSQHHDSSLNPFSLSTQSTYQPHNSTTPNPGAASNPGGPVLPRNVPSSKPNEPRSQNLTATITSPTASPHARIQLASPNEATPTEPSHANIDAVEITLRSPQILAEARNKDPQPNAISDAMPSNPADTIIQPQILTAAPTHDDAGKTNADNGRTSLDRKRMYVALESAAKRLCSRPEWQQESVICTPVPTEARAIAPATTMSTVAATPSVFAPTTTAPLSAQTLALSSIPTTSPPTASSETTSSFFSLDWDDIAWRERACEQNNRYNSSIIVAGRLSLLRNAIVGRDVFYLVLHQIFSLTFVNMDFASNLLGIPKHEMTLIIRVMSSIICSSSDVGQNFHLFAISFPFPWFKMSPGDLPKEVGKTIRAIPHFLRRISTLYPKMLSHSKARGYPLLPRELSRGLLLPSATMLRAIYCSNCRTLGITDGHHPNMPQILVTLRAQMTARFLLCLQIENNSQFTSAELKHAEIKAIGHMKLCVKTYAEFLRNNNIPQSTVVSKPPTLVPTVAGTSQTQALAQIQTQAWAQAQISPRAQTRTQTLDQTRRQRRTMYPNEQAHTPQQQYYLNQGRQLIQGRPLQQTERQQQQRQLQRTETQCPSLQSNPGLLPNQLGSTPLSLPASLQNQAAISAINTFAAGIPSNTPSRGNQQARCNIDAWSQPQLQPQQQARLEIPSLHSQAYQAQNHHTRAQQHHPTRPVPNLPAQALLSEFQLLQTVQNRPQRLYSQLLQHPNASPSIASTSNAPSSNMAVAASNSIAPPQTPDKLQRLLLPTSNARIHPNLYPVNEYLAIQAACHNAIAMPPIMQLGYEPTMTHTTHLQYASGFAHPPTLIEKICIIDNALFSVSSNDLRMLARHQPAPGFHQLKIRKYQAGSLTLRMRMCYFPSSHKGEIRLEDWLVAKHVWPTLITIKLNGNIQTNVGRKEVFHHDLPLDITNLVVGGMNELSVGYFQKKAGFELYYAIEFVEIETPHTLHDRILNHQTLPAAITIETIVSRLTATQDDDILASEEMVISLRDPFSTRILKHPVRGMKCSHLECFDLHTWLTTRPIIRKCSLVTGQPCTSENICGLCQRRPKSVLESPPSNPDRWSCPVYGCSEDASPNNLRLDMFLLSVCIEIPASDDVQAVIVDKLGNTKLKFVTMDDATNQTQSLRKGRPLPSTGLDVAKSQDTTHTGGREESQGETTAQEPVVIDLDLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZND4</accession>
    <name>A0ABR3ZND4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phospholipase/carboxylesterase/thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000444</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050565">
        <property type="entry name" value="LYPA1-2/EST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655">
        <property type="entry name" value="LYSOPHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655:SF67">
        <property type="entry name" value="PHOSPHOLIPASE_CARBOXYLESTERASE SUPERFAMILY (AFU_ORTHOLOGUE AFUA_5G09340)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
        <property type="entry name" value="Abhydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phospholipase/carboxylesterase/thioesterase" evidence="2">
        <location>
            <begin position="30"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="251" mass="26977" checksum="E53857722CA56761" modified="2025-10-08" version="1">MPPTRVPSEADFAHLCNRLPHTLHFSARPSTSAILLLFHGFGDTHESFARFAAAMNLPNVLAISVRGPTPLPAMFGPDTPAGCFHWGDDIVLDSRSGAIDPDPGFARAVAVVWDELIAGVLLAKCGWNTRDILLFGLGQGGSFALALAQHAAKIATTGGAVGTGAQQQVDRFKGVVSLGGPMPLSAVARSVKASSSILLVQLDPNTEETAKKHFTNVQAIRWKRPQVDMPRSREEMLPIMQYFAESLRQGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNX5</accession>
    <name>A0ABR3ZNX5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA replication licensing factor MCM2</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">MCM2</name>
        <name evidence="18" type="ORF">Cpir12675_000412</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008045">
        <property type="entry name" value="MCM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF44">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12619">
        <property type="entry name" value="MCM2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01658">
        <property type="entry name" value="MCMPROTEIN2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 18" id="KW-0347">Helicase</keyword>
    <keyword evidence="9 18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="17">
        <location>
            <begin position="488"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1901543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="900" mass="100196" checksum="A5EC8C488C5F6965" modified="2025-10-08" version="1">MSSPPVPRDSPDLGPGPSRSSRKRSRSRDDHMSIGSSPALPSSPPMRGDVMRHGADDDDVIEDDQILDVDDIDDLDELAEGEVDLFNDNFMDDYRGQHSDDGYEGVGLDDTDYGAMNLGSRRALESEMNRRDRQVARNRNLPSAFLGSDFDNDDIDLTAQPRRHRNLYDEAPDDMGMDIMEEQLSSQALSDMKTNELADWIATPSAQRTIKHEFKRFMTESIDSSGNSHHATMMLELASRNAETITVSYELLSEHNASLAYMLCNAPSQVLKLFDEVAMDMFIDNFPDYANIQPEVHVRFKDLPINYTLRQLRQSHLNCLVSVTGVVTRRTGVFPQLKYVKFDCTKCGITLGPYQQESNVEVKVSFCMNCQSRGPFTLNTDQTIYRNYQKITLQESPGKVEAGRLPRHREVILLWDLIDTCKPGDEVEIVGIYRNSYDAQLNNRNGFPVFATVLEANNVIKENDDLQGFNITPEEEKIITALGKEPDIIDRIIDSIGPSIYGHRDIKTAVALSLFGGVAKTTKGSHHIRGDINVLLLGDPGTAKSQMLKFAEKTAQRAVFATGQGASAVGLTASVRRDPVTNEWTLEGGALVLADKGTCLIDEFDKMNDQDRTSIHEAMEQQTISISKAGIVTTLQARCGIIAGANPIGGRYNSTIPFSANVELTEPILSRFDILCVVRDVVDPEEDKRLASFITDSHEVSHPTWKDSANLLRNAIEVEREKCRAATLAYQQLVASGAATAHDAPPPGRSAELIAAEEELKAWGSRGKKKGGPIDQELLRKYITYARKKVRPVLYQLEVDKVSRLFADMRRESMITGAYPITVRHLEAILRITEAFCRMRLSDFCLQKDIDRAIEVTIESFIGSQKASCKRALSRTLSKYLVKRNNGSNKRGGAAPEANM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPZ6</accession>
    <name>A0ABR3ZPZ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sir2 histone deacetylase Hst2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">HST2</name>
        <name evidence="10" type="ORF">Cpir12675_000028</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01408">
        <property type="entry name" value="SIRT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF6">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="9">
        <location>
            <begin position="16"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="327"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="349"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="381"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="406"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="420"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="442"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1902130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="463" mass="50654" checksum="32EA17F8A2A608B9" modified="2025-10-08" version="1">MGQNESASLGPDITPYKLSPRTLDAVAEFILQGKAKKIVVLTGAGISTAAGIPDFRSPGTGLYNNLKRLNLPYPEAVFDIDFFRKHPEPFYVLAKELYPGKFYPTISHAFITLLARKQLLSKLFTQNIDCLERRAGVSPDMIVEAHGSFATQRCIECRSDFDGDIMREHVQAGRVARCTARGCHGLIKPDIVFFGEGLPMEFTNSAYLARETDLLLVLGTSLTVYPFAGAADMPSRGTPRVLFNREQVGSLGQRLDDVLELGPCDRGVRRLARLLGWEDELEVLWRDTVGEKEALRQMGVQDTWEEEIGEFDDEIVDKMAQGLGNLELSEEEDGPVESDRPGSLSYKKLSQDDGGKKSKEKMEDPAKPLGAEISPEAVPSKTESAPASPPETLNTVDNQGKETLGSPESSESSESLVDVVKTEKTEKTKKVEVSQSTEIKDTTSTARADSTDSPSTENTATAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRE5</accession>
    <name>A0ABR3ZRE5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 13">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="11 13">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">ubp14</name>
        <name evidence="18" type="ORF">Cpir12675_000165</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11 13">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 11 13">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="11 13"/>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02658">
        <property type="entry name" value="Peptidase_C19B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14385">
        <property type="entry name" value="UBA1_spUBP14_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14386">
        <property type="entry name" value="UBA2_UBP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016652">
        <property type="entry name" value="Ubiquitinyl_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041432">
        <property type="entry name" value="UBP13_Znf-UBP_var"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF664">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17807">
        <property type="entry name" value="zf-UBP_var"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016308">
        <property type="entry name" value="UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 11 13" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="9 11 13" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="7 11 13" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBP-type" evidence="17">
        <location>
            <begin position="149"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="16">
        <location>
            <begin position="300"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="15">
        <location>
            <begin position="591"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="15">
        <location>
            <begin position="658"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="363"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="697"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="368"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="708"/>
            <end position="717"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR016308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1902059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="795" mass="87733" checksum="93A61A91895BE2CD" modified="2025-10-08" version="1">MPPPPAKIALEPPRLSQSVYREDCTQCFDSIDDKTGLDVCLQCFNGGCTKDRSHAALHASLRSHPLVANIRRVRKVVEREEPPLKMSKLAIAAETDADRYDTIVVARCLECNLDIDKTSEKLEPVISGLMKANTFSRQEEVKAWELELNECEHVICLEQDMAKEIKSGDLGHCTSCDLHENLWLCLQCGNLGCGRKQLGGVDGNSHGLAHATESGHGVAVKLGSITPEGNADVYCYKCDEERIDRNLAAHLANWGIKLADRQKTEKSLTELQIEQNLRWDFSMTTSDGLQLLPIFGAGLTGLKNLGNSCYLASILQCLFALPAFKERYYKPDDVPPNVFEPAADLETQLQKIADGLLSGRYSKPDESAMSQSPSPLNNPEQQAEPVHQRGIAPSMLKHLVGRGHGEFSTMRQQDAFELLQHLFTLITRASKADGTPDPTLKFRFALEQRLQCISCKKVRYSTIEQDSIFVDVPKDKIEASEDNEDKKDVYRPVALKECLDRFTGEEMVDLTCAACSSKDGYIKRQLFKTFPEVLVINASKMTVVNWVPVKVDVPVIMPLEPFLMDEYMSKGLQADEEELPEEKEPEASVFIPDATAMAMLEGMGFPPNRCHRGLHATGNNDANAAMEWIFAHMDDADIDSPLVLSSGSGAGPGAAASMADPEKIQMLTDMGFAVPQAKKALRETGADMEGAVTWLFSHPDDPGDDGSETVQQQSSANEAKDPCIAGSPGVPAKFQLQSLVCHKGTSIHTGHYVAFIRKQIEGQDTWVLFNDEKIVKAVDADEMAKFAYVYFLSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YB52</accession>
    <name>A0ABR3YB52_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006983</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000485">
        <property type="protein sequence ID" value="KAL1885348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="147"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1885348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="215" mass="21846" checksum="39AA3B41FB3D391A" modified="2025-10-08" version="1" fragment="single">MDSSPAIATQHPSPPAAVASPSSSSSHSPIAKPASALTTTATSAASVFSALFSSSNSPIQAPPAAALSNAKLVSRRQSLNLPLSSSRNRSISYTASQTKNLLAFAFNALGTFTDSSAASHSNNPRSITAQSNSSFTNLLAPPTQADQSLSPQSSRSSLRRGSAATVGSASGFVVSLPNADTTTTETPLSGSSHHKRHQQSVHLGGPVTFAFASQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YC09</accession>
    <name>A0ABR3YC09_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">GH18 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Cpir12675_006988</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the glycosyl hydrolase 18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000497">
        <property type="protein sequence ID" value="KAL1885342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00598">
        <property type="entry name" value="GH18_chitinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF337">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="7 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046540141" description="GH18 domain-containing protein" evidence="11">
        <location>
            <begin position="21"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="12">
        <location>
            <begin position="64"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1885342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="215" mass="23077" checksum="7778E165ABAF9485" modified="2025-10-08" version="1" fragment="single">MVRLSGLASALAMWATTAAAAVASGTAPGIGTYNAMSTGAYKAAHTGSSSPSKPPPITDSSEPARYIMYFDQWHTSVLPNKTITAGITHVVMAFAEPLVFTTDPIGEYRPHMELDKVREMFDENVKISMAIGGWGYLVGFREGARSPESRALYAKNIAATVDSFGYDGVDIDWEYPGGNGEDYKQVPSDLSEIEAYPLLLAEIKNAIGDKELSIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YCG1</accession>
    <name>A0ABR3YCG1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ribulose bisphosphate carboxylase large chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">HGT3</name>
        <name evidence="10" type="ORF">Cpir12675_006948</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000447">
        <property type="protein sequence ID" value="KAL1885999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF73">
        <property type="entry name" value="METABOLITE TRANSPORT PROTEIN YDL199C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="297"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="383"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="417"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="448"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="474"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="544"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="137"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="588"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="665"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="64"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="588"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1885999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="687" mass="75526" checksum="142881A897D2AA9F" modified="2025-10-08" version="1" fragment="single">LRYPITASQYSENAPPLSLTEDYSDFSSESWTDTGDIAEQLDDEDPLRDCIADDPHDEILHGVKRPLKKKRRRNHTNTRSWSPTHDNIRRESIDKESIVVPSFIGHRTPGSLERLFVSIMGSNPIHGLTGKPLIYFTSIFVSLGVFLFGYDQGVMSGIITGPYFKDYFNEPSKAKVGTMVAILEIGALISSLVVGRVGDIIGRRKTIFYGSCIFFIGGALQSCATNMEIMMLGRIIAGLGVGALSTIVPVYQSEISPPHNRGKLACIEFSGNIIGYTTSVWVDYFCGFIESNLSWRIPLAMQCVMGALLGLGSLIIVESPRWLLDNDHDEEGIVVIANLYGGGDIQNSKAVEEFRQIKKDVLIQRQEGERSYSEMFRRYSRRVLIAMSAQALAQLNGINVISYYAPYVFESAGWVGHAAILMTGINGITYFLSTIPPWYIVDKWGRRVILLSGAIAMALSLTAISYFIHLDTSWTPSMVVVFVMIYNAAFGYSWGPIPWLYPPEILPLSIRSKGASLSTATNWAFNWLVGELTPILQEWIKWRLYLIHAFFCLVSFVVVYFLYPETCGVRLEDMDRLFGDASTAIGTPSMHPNETASLIPGSSSGASPRARPGQFTAENFAVPGFSLDPPDHLSGGAAVAAATSARKNGSNAAVDGARGWLSRVTGIGGQSRDSDAEYAPINQSDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFI8</accession>
    <name>A0ABR3YFI8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">34-kDa subunit of RNA polymerase III (C)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RPC34</name>
        <name evidence="7" type="ORF">Cpir12675_006850</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000393">
        <property type="protein sequence ID" value="KAL1886923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007832">
        <property type="entry name" value="RNA_pol_Rpc34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016049">
        <property type="entry name" value="RNA_pol_Rpc34-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12780">
        <property type="entry name" value="RNA POLYMERASE III DNA DIRECTED , 39KD SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05158">
        <property type="entry name" value="RNA_pol_Rpc34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028763">
        <property type="entry name" value="RNA_pol_Rpc34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="211"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="212"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1886923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="413" mass="45976" checksum="042FAB62E0EED9C4" modified="2025-10-08" version="1">MSRKRAQAVVPAADVKAEDEATSKVNIYKELLYDSMQANGTAERLYTQVDLQELKAIPDPNITTLLQVVQELVNDKLLVPCTGREGGLAWKWRDAREAEKYKQCTTPEQKMVYQMIDDSGSDGVWSQTAQKRLGMHENVFKLAIKQLLGKGLIAQFKSVENPNKKMLIKASIRPSEKATGGPWYTDQYLDEAFIEDLERVIYDFVKQRSAYRSRGGPSTSSRTLQPKKGIIKGGEKVARKRTANEISTEDNSDMPAKPAAIDLADNVQTPTAVTTIAAPRKDVLLPLPAGYMGYPTVRDIARILSQSGITTNTILSEEDVQKLVNVLEFDGLIERIKVGTRIGYRTVRAVKQSLDQWAVPTEPGKQEKGIPDQYGTPFNEVPCGRCPVFDLCEEGGPVAPSNCEYYKKWLGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFT8</accession>
    <name>A0ABR3YFT8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter ATP-binding protein arb1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ARB1</name>
        <name evidence="6" type="ORF">Cpir12675_006694</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000354">
        <property type="protein sequence ID" value="KAL1887102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF15">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="80"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="391"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="612" mass="68088" checksum="6DCE408448B60AA0" modified="2025-10-08" version="1">MAPSASKEKRLAKKAEKEGKTSKLAAKRAAKAGANGEDVPATSAESMDEVQRLAAQMDKHGLSDRVTTGVLSSSKLSRDVKITSTSLVFHGRVLINDGTLELTYGRRYGLLGENGCGKSTLLKAIAAREYPIPDHVDIYLLNEGAPPSDLGALDWVVTEAQNELARLEGVAEKLLEDEGPESPVLLELYDHIDKMDPTTFSTRASLILTGLGFNKQTIQKKTKDMSGGWRMRVALAKALFVKPTLMLLDDPTAHLDLEACVWLEEYLKKWERTLILVSHSMDFLNGVCNNMIDMRIRTLLYYGGNYDSYIKTRTEQETNQMKAYTKQQDEITHIKKFIASAGTYANLVRQAKSRQKILDKMEADGFIEPVVPDKVFTFRFADVEKLPPPVLSFDDVSFAYSGNAEDDLYKHIDLGFDMDSRAALVGPNGVGKSTLLRLMTGKLSPREGRITRHTHLKLGIYSQHSAEQLDLTKSALDFVREKYKDVSQDYQYWRQQLGRYGLTGEAQTALMGTLSEGQKSRIVFALLAIDGPNMLLLDEPTNGLDIPTIDSLADAIKAFSGGVVVVSHDFRLLDKIANQILVCDNRTIKLWDGTISDYKNHLRKRMIDKGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGN4</accession>
    <name>A0ABR3YGN4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">FIT family protein scs3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_006526</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000315">
        <property type="protein sequence ID" value="KAL1887500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019388">
        <property type="entry name" value="FIT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23129">
        <property type="entry name" value="ACYL-COENZYME A DIPHOSPHATASE FITM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23129:SF0">
        <property type="entry name" value="ACYL-COENZYME A DIPHOSPHATASE FITM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10261">
        <property type="entry name" value="FIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="334"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1887500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="367" mass="39667" checksum="EBCF8BA28A2E1C83" modified="2025-10-08" version="1">MDTTNSSDAHARSRGHTSSPSSLAQNRAFGTATATKPTVPYPVLYGPTSMMLYIPTQCELAAYAIFPALLLFGGAYSLLSPTVRASTYDPVTQGHVQDPELLPSYFASKHNVFNRYFVKVGWAWVTAAISSFALLNPVLGPITGGTSLMAAKDSTAKLAVYRRARVLVRYAAVTLAWAATTQWFFGPPIFDRWFRWSGGMCYPVEAFGPTGTLLAAEAPQKAGADAEALNILAYTATTCKRVGGRWYGGHDISGHVFLLVLGSGMLLQEISWVMWPRGNRALILGDGSVLTYGPGPGLVRGIGFTGVFILGVVALKLWMLLMTAIYFHTWFEKLTGLLAATASLYLVYIVPRFMPTVRAVLGAPGLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH93</accession>
    <name>A0ABR3YH93_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Rho GTPase activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">BEM3</name>
        <name evidence="6" type="ORF">Cpir12675_006462</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000304">
        <property type="protein sequence ID" value="KAL1887656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13277">
        <property type="entry name" value="PH_Bem3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050729">
        <property type="entry name" value="Rho-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176:SF129">
        <property type="entry name" value="RHO GTPASE ACTIVATING PROTEIN AT 16F, ISOFORM E-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176">
        <property type="entry name" value="RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="4">
        <location>
            <begin position="1035"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="5">
        <location>
            <begin position="1332"/>
            <end position="1525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="163"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="464"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="572"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="642"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="702"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="781"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1017"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1154"/>
            <end position="1246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1524"/>
            <end position="1703"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="432"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="7"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="69"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="121"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="213"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="229"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="249"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="307"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="331"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="589"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="645"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="675"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="709"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="795"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="812"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="833"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1019"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1154"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1176"/>
            <end position="1185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1195"/>
            <end position="1207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1550"/>
            <end position="1560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1613"/>
            <end position="1637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1703" mass="184984" checksum="FB9005BD6F4CAEF0" modified="2025-10-08" version="1">MPEYPKQESSTHQNHNHNQSQTLPSNTSSAQPQQDSQKFAFPPRSHSFHGAKSRPHANIATVPSPAPESPTSSPSLPTALTISPTRRYFSLNYGHSSSSSASAVLERQGMPQQQQQEQQQSYPTLSNPPTKSQSPQFPPRHSSQVAVPPESWTINRAYKPIGTSARSSSFSHSRLHRPIPSRLHTSISAASITYDPKNNPIRHDNGPATAPLRLPPAISPTPPLGAGDSTTASSSSSSSSTLQRLAATAPNSATHPTAISTTDALDIETQSPQSYSSRFPDPTCESVYYSDSSSDEESLDQPHKPKSTSVEPSNDRSAPFPGILNSLIPRTSSPSSSMPVSTMAGPPVPRELAMSGSPRQASMDSVISALSIKGKPGSAELSASTVASDIDNLVKTAGSPEAVIQYLLKDKASQSQQNAQLWRLVDKQRAMILGLNKDLERALKDKEKYRKKLKEVLSVHDGQNSDVLKESDAASDVTSRPGQIPDSPNLESDTNLKVSQASMAPYPITPPADYKNTPESVDSGVGELLDPQKTMPRAEEYAYGKFDSEKQEVASQLKRRQENDGYDLHINMRIPPSRSLPSPTATGPLVPPPSKPPPAPPSIAMTSNIVPQADQDLAQFPSPPNKKASMPSWARQDLLRHHTVEDEETETDYEDILDVEKQKYVNSSTTADTAGDNRGRRQTREEDDAVRVKIAQILEVDGQSKKSTAESTTPKTVIDTNIDRTPAPPTVIAPSPTSLSQRRDHVPASLNGLMKKTVQAMSSQDQGYNQSQGQTLSTADISAPLRSPGLPASPSPQSAFAAAQNAAASPSPRLPRQPIPMPLGLALKGRTESAPTLTPLSAQSDLSSVAPTPAMIPRRGTESSTERRKIFKGFQVDEFPDLLLPPNALPSISVRVASSRMKPSRASLVSLTQLEEDPVFTLAVVSRSDQGELWRVEKDSMSLLKLDQRLKQFSQFTARTPDRSLFNGHSPAKLDARRVALDQYWEDAVNVHFDVTTALELCKYLSTNTLPPNFDENWDSSVASGQGSKNAPGDGAFRSGYLTKKGKNFGGWKARYFVLSGPTLKYYETPGGAHLGTIKLFNAQIGKQAPQTESQASGANDDFDNQYRHAFLIMEPKKKDSSTFFKHVLCAENDDERDQWVKSLVQWVDYRDLDADKGSKNGDRPATSAGEHTTKSKNNSSSSDAKALKKKHQAKGSSTQHHQTGSETLIGVRYDSLKPASSNNSGREGFRNTLIGLPQNPRDQDPTVKENVPLISAPQKINVMSDVSTFVSRMSHVPVSANGMLSSDEKKQRKRSFFGFGVKTRSSSEGQDSLFDSSATNYNGPIRPIFGAQLGDAVRYNKPVDVNVPLPCVVYRCIQYLDDQGALSEEGIFRLSGSNIVIKALKERFNTEGDINLVTDDTYYDIHAVASLLKLYLRELPTAILTRDLHIEFLSVLEMPVVAEKCAALGDLVKWLPQANATLLKYLIAFLIKIINNSAVNKMTARNVGIVFSPTLNIPAPVFAMFLQHYETIFGIDPEHYELPSPISEEDSSSVNSFHPSFDPIPTRPATASGASASASPHRQRLMDQSRNSPTPPLLQDRHNLRGTPTPPPGGGTPSTGTNFSMPQAWDPSAQQAKGSGSNGYNHNQHVYSNSQASSTHGLGHGYGSGSASSSSEMMLGVPSHEPMSMSSNSRRRESAIYGSFGAIQQQQGGSRLREETRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHD2</accession>
    <name>A0ABR3YHD2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_006437</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000300">
        <property type="protein sequence ID" value="KAL1887723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185:SF1">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="206"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="222"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="273" mass="30562" checksum="08E9A8A608986CB6" modified="2025-10-08" version="1">METLPTLLTTYGISRSFAQCTVSEVAKAASAANNLSGSIKTGEDEEVFIDAQYGYNNPCEVLISETKRQFPDRELIILSIGTGVNDVVEIKDAGESLNLAFSRIATTSKQSDLRLKNIYGGSGVYHRFDVENGLRDSKSQSCQRVGSIAAHTRNYVQENETSIMEFVKAFTGARSSLLVQPRKEYGEHYMEKSRYCHCANNSIERSPSSVDYGENPRPRSPNHGQPQQKPPRTNWVNSCMGEKESRLKSWWSNTAGSKAQVKRMMNFLSPRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHG8</accession>
    <name>A0ABR3YHG8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Uridylate kinase</fullName>
            <shortName evidence="9">UK</shortName>
            <ecNumber evidence="9">2.7.4.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP:UMP phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Deoxycytidylate kinase</fullName>
            <shortName evidence="9">CK</shortName>
            <shortName evidence="9">dCMP kinase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Uridine monophosphate kinase</fullName>
            <shortName evidence="9">UMP kinase</shortName>
            <shortName evidence="9">UMPK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">URA6</name>
        <name evidence="12" type="ORF">Cpir12675_006652</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>UMP + ATP = UDP + ADP</text>
            <dbReference type="Rhea" id="RHEA:24400"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="9">Binds 1 Mg(2+) ion per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
        <text evidence="9">Predominantly cytoplasmic.</text>
    </comment>
    <comment type="domain">
        <text evidence="9">Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.14" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000342">
        <property type="protein sequence ID" value="KAL1887201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03172">
        <property type="entry name" value="Adenylate_kinase_UMP_CMP_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006266">
        <property type="entry name" value="UMP_CMP_kinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01359">
        <property type="entry name" value="UMP_CMP_kin_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6 9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="NMPbind" evidence="9">
        <location>
            <begin position="164"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="LID" evidence="9">
        <location>
            <begin position="260"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="144"/>
            <end position="149"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="192"/>
            <end position="194"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="223"/>
            <end position="226"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1887201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="326" mass="34979" checksum="E6B36C5B0210FB50" modified="2025-10-08" version="1">MLSLRTAIATATRSSGSVAAKPALRNRMVAAGRRAYSAAAPSPPPAPKKKDGMSVLPFLGVVVVGTGAYVMLVNSRKDLAEQKRAQMAAERAAAAAASTAAAAPPEDVPAPEPTTTIESNAAAIDTPAFNPDDVTVFFVLGGPGAGKGTQCARLVSEYGFTHLSAGDLLRAEQDRPGSQFGDLIRDYIKNGQIVPMEVTIKLLENAMTETMGAEKKGRFLIDGFPRKMDQAVKFEESVCPAKLVLFFECPEKELERRLLERGKTSGRADDNIESIRKRFRTFVETSMPVVDSFADSGRVVRIDSSPSPVEVYNTTIEELTKKVGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHJ2</accession>
    <name>A0ABR3YHJ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Copper transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CTR2</name>
        <name evidence="5" type="ORF">Cpir12675_006416</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000297">
        <property type="protein sequence ID" value="KAL1887784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483:SF115">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="4" id="KW-0187">Copper transport</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="156" mass="17395" checksum="03D8CFC6283561C9" modified="2025-10-08" version="1">MDHSHMDHSHMDHGDAPGDNMPMCSMNMLFTWDTNNLCIVFRQWHITSPLSLAISLLSIVAIAAGYEAFRSALRGYEAAVAKRIETAPRQTQEQVAKRAHLIKAVMYGVQSFYAFMLMLVFMTYNGWVMLAVSVGAFVGYLMFAESAPLANEGVCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI21</accession>
    <name>A0ABR3YI21_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000297">
        <property type="protein sequence ID" value="KAL1887789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="378" mass="41988" checksum="8E18AD44BB22E704" modified="2025-10-08" version="1" fragment="single">QKYQGSLYKNKNKKQRLNNSQDIATPSRNTKNTEMAAVQSHPVPEHLRQYQAPESLKCTPLAPAPRTVSINAPVNVFDFFVGQATPTASTVSRDNELVPFQGPDEDDDNDTLLAERTDAAAPLKVPPPVPAPPVESFETPAPKSYKPSKHREPSSKTDKKRKRPHVDSIDTGIANTPTLHTGLSVNMGRLMRSAMPPSPEYSGGDTNGHSPSSPLKKSKQHTGILEALWGTSKSKSKSKSASSSPKPKKTRSSSKSKSKESSSKKTSSSHRHRHHQKTAAKLIEYNKDLEKKSDKGTGGEGQMVLYNNSRAKSFLGIVEDSENERGYSIHKALKRYHREFNKEKSSSNRVLEDKELFKMLRLRRNDRGEIVVFVPDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI97</accession>
    <name>A0ABR3YI97_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_006325</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000282">
        <property type="protein sequence ID" value="KAL1888055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1888055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="206" mass="23587" checksum="376266C2BB20B20B" modified="2025-10-08" version="1">MDRQRCLQTRTERYGRNSLDPVVHLYIDMEHEAVTIYEDNLRSESPSRRALDIQNIYTALCLRAGIAPTRMQWIGMDVDDRATAIMLREHRVDNELGLDDFYITPGQAGWEAFSNNRYFQAAAKVIPQVEIDRIAVRRQQRGIQVPGYPPVDVQSITFSFKQPDSEDHDASIDRIDENLLEIKINNNLDSIVKSAQHAILVSSTTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ39</accession>
    <name>A0ABR3YJ39_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongator complex protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006379</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ELP6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000290">
        <property type="protein sequence ID" value="KAL1887892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19495">
        <property type="entry name" value="Elp6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018627">
        <property type="entry name" value="ELP6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16184">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16184:SF6">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09807">
        <property type="entry name" value="ELP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="278" mass="29823" checksum="61AD6173C5011B63" modified="2025-10-08" version="1">MASRAIPYLLTPYLSLSDESSLTLLTNVLSATSNWLVVRYLQSLLPVRGKANDDADANDGCVTVVLVSFMRDFAFWSECSGKLGVDLSRHCREGNFVFVDGLTSLFASSTNPNSPPTVPATKGRVTLTSSKLTVIQGEIQAAVASLAGPGKNVVLIIDQIDFLLAATEGSATELQNAVLSLRENVHSTILAVAADSALIAEQNTALERNHAGLALDLAHQADTVISLRMLDTGVARDVSGVMRITRGGQDHDERNTEEHEYLYYVSGDGGVRVFERGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJM3</accession>
    <name>A0ABR3YJM3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">PHO85 cyclin-5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">PCL5</name>
        <name evidence="1" type="ORF">Cpir12675_006271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000275">
        <property type="protein sequence ID" value="KAL1888165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF36">
        <property type="entry name" value="PHO85 CYCLIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1888165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="666" mass="71985" checksum="02D4C7780C318D39" modified="2025-10-08" version="1">MNHSSIQNLSSPSEFVYGGSPHRMASSFTSEIFDVCSISSSQTSLSPACDFEECASSNRCGGSVNTSTVNSASATNAALFTALPPILPLDVSLPREPTVAPMAPAAPLIPAAPLIPAAPLIPAAPAVSIAPAAPIASAPYYGRRTTNLGNTRTIPNLVRQPERKVNFVDTLVESATLIVEAIWPLSDAMHCQVSQSAKSPLKLRTFIEETLRRSRTSYSTLQVAMYYLILIKPHILSQSNSASQEHRDSSPSRALQCGRRMFLISLILASKYLQDRNYSAKAWSKISGLPISEINQNELAFLQAINWKLYIHESLFSRWTTFNLNFPPPPPGPGREKDAAALRWRDMILDLDVEITNVDLTVKPSPPAGVSMPSLLSMPRSNTLPATVEMPTTCSTAPLRRFSYGHMSLPTMRMAAPAASPTPSAFSVASSAPCQRSMAMAMECANASFAVRNIDRYHMNSSPAPQLSAFMGPMRCSPLAAQSSISSSPESMISDDSRSTVSSVSYTPIHESGTYPVSLPCSLGPSRGPIRPVRMQTTSFSRSNSSSLPKIYENKAPGVFPLSDFGVPTVQSPVSFVEQEAARILQDFKSQTAAPSLGPKRSFSIMSYESYGSAGPANDSSLLGSSRDIWMTPESALESSKRMRYNQDMTPYALNYLMSQYPTASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKL2</accession>
    <name>A0ABR3YKL2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ATP synthase subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">ATP1</name>
        <name evidence="16" type="ORF">Cpir12675_006024</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000242">
        <property type="protein sequence ID" value="KAL1888849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18113">
        <property type="entry name" value="ATP-synt_F1_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18116">
        <property type="entry name" value="ATP-synt_F1_alpha_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01132">
        <property type="entry name" value="F1-ATPase_alpha_CD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.150.20">
        <property type="entry name" value="ATP synthase alpha/beta chain, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01346">
        <property type="entry name" value="ATP_synth_alpha_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000793">
        <property type="entry name" value="ATP_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038376">
        <property type="entry name" value="ATP_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033732">
        <property type="entry name" value="ATP_synth_F1_a_nt-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005294">
        <property type="entry name" value="ATP_synth_F1_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00962">
        <property type="entry name" value="atpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009884">
        <property type="entry name" value="PRK13343.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48082">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48082:SF2">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00306">
        <property type="entry name" value="ATP-synt_ab_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039088">
        <property type="entry name" value="F_ATPase_subunit_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47917">
        <property type="entry name" value="C-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="N-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="6 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 12" id="KW-0139">CF(1)</keyword>
    <keyword evidence="5 11" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit N-terminal" evidence="15">
        <location>
            <begin position="67"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding" evidence="13">
        <location>
            <begin position="190"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="ATP synthase alpha subunit C-terminal" evidence="14">
        <location>
            <begin position="420"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1888849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="551" mass="59412" checksum="12A88AE584842517" modified="2025-10-08" version="1">MFRTALRQSSRVLSAAGRVAAARSAAPAVFNASSIQARTYADKASPTEVSSILEQRIRGVQEEAGLAETGRVLSVGDGIARVHGMANVQAEELVEFASGVKGMCMNLEAGQVGVVLFGSDRLVKEGEVVKRTGQIVDVPVGAEMLGRVVDALGNPIDGKGPIKTTERRRAQLKAPGILPRESVREPVQTGLKSVDAMVPIGRGQRELIIGDRQTGKTAVALDAMLNQKRWNSGSDETKKLYCIYVAVGQKRSTVAQLVKTLEEADAMKYSIVVAATASEAAPLQYLAPFTGASIGEWFRDNGKHSLVIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNRKLGGGSMTALPIIETQGGDVSAYIPTNVISITDGQIFLEAELFYKGIRPAINVGLSVSRVGSAAQVKAMKQVAGSLKLFLAQYREVAAFAQFGSDLDAATKQTLARGERLTELLKQKQYSPMAVNEMVPLIYAGVNGFLDTVPVNKVLQWEADFLAHLKSNEAELLATIEKEGALSKDLEAKLKANVQSFTKSFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKW6</accession>
    <name>A0ABR3YKW6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WD repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_006312</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000280">
        <property type="protein sequence ID" value="KAL1888079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051858">
        <property type="entry name" value="WD_repeat_GAD-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16017">
        <property type="entry name" value="GASTRULATION DEFECTIVE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16017:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="119"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="231"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="344"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="492"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="576"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="95"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1888079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="609" mass="66833" checksum="C6E2B92D79E4F412" modified="2025-10-08" version="1">MSDDNFEIETPDLAPDDPMRAFLPKSFGKQSKQANISAQIDRSKRTKVAAEPKKPQTQDLVGYGDSNSGGSSDDDGDGYGPQPQPQKPVTKSDDSADDSDDDDDDDDDDEFPVSHELVVKTHERAATTVSLDPAGGRMITASMDCTIRLHDFASMTPTTIRAFRTVDPWESKAKNSTADSHPIYHVEFNPLSGGMFLVTSAHPQAKLLSRDGDIVTEFVKGDMYLRDMNNTTGHISEITTGTWHPTDRNLFVTAGTDSTLRIWDVNHRRKQKDIIVWKSKSAVQSGRIKMTAVTWAAPPSGGNSVLVTAALDGSLAVYNGNGPFWRPSAEIRNAYAAGTWTSGIDVSSDGRMVVTRGGDNTIKLWDLRKFTKPLVETAHESATDAYPMSNIKYAPNSSAIITGSPSGNLHILNPANLKPELVTPVTPGSAVITVDWHPKINQIVTTSANAEVHVLYSPYMSTRGAVEVMSRAPKKRHIDDDPSRTVDQAIGLSGDSIVNPNGILPGTRIPTGGGNKNSKHKDPRRPQMQTKTPFMKNQPDEKHISENIPLAKMLHEDPREALLKYAEVAKKDPMFTKAWNETQPETQYAELSDQEDNGKEKPQRKRLKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL00</accession>
    <name>A0ABR3YL00_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA-directed RNA polymerase III subunit RPC4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_005948</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000234">
        <property type="protein sequence ID" value="KAL1889030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007811">
        <property type="entry name" value="RPC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13408">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13408:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05132">
        <property type="entry name" value="RNA_pol_Rpc4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="261"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="382"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="467"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="79"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="141"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1889030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="523" mass="56983" checksum="53ABDAFF87BA607C" modified="2025-10-08" version="1">MNRGTAPTGRRGRAGYGRGASLIARSATPSAEGGSSADGATLPSGSSVPIIKTEPGVSSTTTPVSRGAWGGRYKPKNVRRSEAERAAIAEQEAQKQRERAAEEAKARPRGRFRGGRSRGNAMGQRGRPGNPAGMFGQRGGFDARGRGRGGAEYKISRENTVRIENRESRINADRLGVPAGADNSDMEDEYDFYDEEDKFPGLAPMGIYRTKPKKETVTVTTAAEMEAQENKNAESSDEEIDFKAAISNVKAAIPPEVQVKDVGSNGINFDSGRKKVDDGDTEVDTDVDPTAKNTNKAKTKSKLPVSPEEQQLEADLQLMRNEFSYIKIHDEYENENESDEETNEEKIVEKGIAREGRVYLFQFPPVMPPLRPVKKVRIKPESDGMFVESPTSEPIEVSSASPEGEDDDTSDAEATKATIDNQSGFVGQMVVRKSGRVEMNWGGITYEMRPALKRDFVTSAVLVEYSDEKRHGSGPGRAPDEASQNDGTAVGLGKVMGQFILAPKYEDKSEWMISEEDLLAPTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL67</accession>
    <name>A0ABR3YL67_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Jacalin-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005938</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000233">
        <property type="protein sequence ID" value="KAL1889036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.100.10.30">
        <property type="entry name" value="Jacalin-like lectin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001229">
        <property type="entry name" value="Jacalin-like_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036404">
        <property type="entry name" value="Jacalin-like_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01419">
        <property type="entry name" value="Jacalin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00915">
        <property type="entry name" value="Jacalin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51101">
        <property type="entry name" value="Mannose-binding lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045241657" description="Jacalin-type lectin domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="Jacalin-type lectin" evidence="2">
        <location>
            <begin position="298"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="430" mass="46478" checksum="6E1714095429EDEC" modified="2025-10-08" version="1">MKYNTIATIAALSAPSLVQAASGTLNVLTMNVAGNVPGDKVANAKSIGTYFDELNYDVINIQSDFDNHDSIYETDKHSYRTTTSGGVGQGDGLNTLSNLSFIDFRRIKWDKCSNAEGDDCDTPKGFTFMRARVAEGVYIDMYNLQTDAGMKGDDVAARSKNLAQVSEYIKTWSGGNAVMVFGDTNSIFSRTADNINVFSDQNGMTDAWYTLVRNGDAAADVTCQNPSDTLMCELGDKVISRSSELLTLDATTVEYVGKKFLQSNGNVLSDRDPVHVALTWTQSETLRQSDFHGAPHGNVWFNDAPVVASKANRPKVAAIGFAGGNRVDGVSVALNDNTSLTHGGNGGDWKDFNLEVDEFWVTADLCQGVRDGKTRIFYIKATTTSNRSLEAGKSTDVCVTYNAPSGFQIIGFAGQAGDEIDQLSFIYGLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM74</accession>
    <name>A0ABR3YM74_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein HOS4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_005971</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000237">
        <property type="protein sequence ID" value="KAL1888937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053210">
        <property type="entry name" value="ANKRD12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056485">
        <property type="entry name" value="ARM_KRIT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056015">
        <property type="entry name" value="DUF7593"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24149:SF14">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24149">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24521">
        <property type="entry name" value="Ank_KRIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24513">
        <property type="entry name" value="DUF7593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="549"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="582"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="domain" description="KRIT1 ARM-repeats" evidence="4">
        <location>
            <begin position="699"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7593" evidence="3">
        <location>
            <begin position="1565"/>
            <end position="1725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="50"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="644"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="852"/>
            <end position="1430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1464"/>
            <end position="1529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1852"/>
            <end position="1872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="67"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="89"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="186"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="212"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="269"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="322"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="340"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="366"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="377"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="476"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="644"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="676"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="872"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="908"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="936"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="984"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="999"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1065"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1081"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1152"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1201"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1212"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1260"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1301"/>
            <end position="1332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1341"/>
            <end position="1377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1390"/>
            <end position="1430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1856"/>
            <end position="1866"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1888937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1872" mass="210921" checksum="5E217E4180348FF8" modified="2025-10-08" version="1" fragment="single">NLNLRKPATNPYSRTDFQLDYLSNPLRIVLSEDGLSRSLFSLLDGTMDTYSASKSKRDSPNSPSRSDLGRRTSDDLRYIKSLRPSPGRDSNRHFDHRDRDLGDRERERGREKERGRERDRSTTSATTVKDRDRDRDQDREKDRDDDTATSDVSNAETIVLPGKDGYSPSKARKVKHEREIDDAAGSSQSPVSVSTPSLKLFKSASSINQPPNSSASVSANALSSINGSGNSGATVSSNTVSTSAPDPPSRGILSGVLAHKKVKRADKQSSFVRNNGSSSSHLTAGNPSSGSPPPLKRRRQSNAPPLTGMINLGGHVASDSEPDQHSKSHGPPKDRDKPTNHSTSITTTDKLLKRKVPKVESDEEGEIKPRRSKLSDPTHSSTQPLRNSKDAGNNRPLKSDTQISKSSSKSPAATPRSVSPHSKPTPAHRRSLSTNGVANTKKKKAPAPTSTLASTPSGPVPGLLSTQLHAYDSDDSSSSGSPRPGKGSTFMSRGINERIDSPAGKGPSKKHLDAHGQTLLARACAKGEYEIAKQRLAERPEDLNVADYAGNTPLQIAALHGSEDIVDLLLQAGCNRHCINYDKETPLLDAVDNGHVGVVRLLLEAGVNPRKPNCRGEEPLARVTPDLENGAEIRSLLEKAKATFRHPSEGLREPDDTTADVTEDASGIDIDHSRSSRAPDSPNATTIFGPSTSSHRRAGTARATKTSNHLLYMNVDDKTLRAACGKGDHETVTHLLQVGAEFNYPEAMTAAARGGHEVVMELLLALGNASPDPLAIKTGSPDTATPILAAIGQENIKVMKLLLDQANFNPTRCYKGMTYAELARERKGVNWKEEEELLKKAYDDYCRKHPEKAKPVDRERAHRHLLVDQDQEASRQPRDREYRDKEKGKQRESAPLSAERERDVAATSKLSVKRATSPTPRDPELVKKKTVVKTTLTKDQDSRDRDRESKEEERESRELKKIGELKEKKRAPSADQSDDLPTAKRSLLSTSSVLKSKKKDKDRDGDSKPNLLSDREMSPAIQKKKVKRSVETDAAASSEGEAAKPRRKLMSKGDLTAEQEKNRRASMASNASSMNLQPSSPRDRDDHTLARPIKTEVPSEKYHDRTKALKRDETPGDLASTGKRHRSSTSPPRRSGADKDESETPNIKRRRLVDGELTKEQRQEQRRKKLEKLEREKAEAGNASGDDDHGPRPIKNGILSRESSMNTKTSKPTKEGRERDSSIIRDPARATLKDALKAKKLAVSAKSSDRPIAKASSAAHESDVEMKDAPSSEGARARKDKESKADDQERKRRLTAAAEPDESKAIKREAIEEKKRQDERRAKAEEKRRIEEEAAAAAEAEAAKKRAVEQKEREREREKEREREREKEREREREREKERRRREKEEAEEQERLAAEAREKKEREEAERKREEAERKREEAEKKRQEEEARIRRERELELERIAEEQRKKAEEEKRLAEEARLKEEKRKRDEERKLKEEEERREKERIRRLEEERRLREEAEAKRKAEEERRKAEEERLQREEEDRLRKEQLEREAAEARRRREEERRAAKEAEQRRIHEEQEQARIAGLPALLRWFEMCPNPRQTAVADKFHQMQGVRWDTLDTSLDGTPEGREQWVLNTQAALLLGEKDLTLSRYTGWQRIAATRIAKTMIWRVENDRYALTSPRYYEIGVQLADYYGHPNDPNFMDHNTLERLRNEAMARFFEMDMFFVKLSDLLFVIPSMPHIRNVRLVVEYRELPETEDQLQVLWSGQKWRKDPDIEKYLGFAPRRKYFVNGEFVKENLPGLSAVSRTPFPDANRVPRRFGLTQVFPYEPDYVKLCKEQGLDHLIHLADAPTNAELPVLNGLASGPLEGTGSAVSEPSSEVAQVNGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMJ2</accession>
    <name>A0ABR3YMJ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_005949</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000234">
        <property type="protein sequence ID" value="KAL1889031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF96">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="188"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="46"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="343"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="409"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="409"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="447"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1889031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="479" mass="53088" checksum="A9BDC0965AA981F2" modified="2025-10-08" version="1">MPAALEAKLAAFSPQELAAFMDEYNGGPLFSVTVAFLAISWISILLRTYVRVFLTRSFLLDDCFMLAAQVVYTMSSIFIILGIKYGIGKHNVALEVEDMTHALMFQVLTTETYVLNMMLLKFSIGIFLLRLSMRKVYTYTIWISLIVVTIWSVVILFFNILQCNPIQSQWDITIEHRKCIDSNQVVNAAYSVSAMTIVTDWLYAILPVPMLWDVKMNTQTKVTVILVLGLGVFASVATIIRFQYLVTINDQADVLYAATNALIWTMVEPAVATTASCLSTIRPLLRKLRVRGFETTEGANSMTGGRGPRSGQSRTNHYNEIRTGDMELGSKKTATTTIVVGATETRSSSSSETQVFPPRTTTPLPSAYIPDKHSTSSRTPPPRKFSDPNFFAGSQILHTTRIEIQSQSIGVSANAESRPSPSEPHSQLSDLSTTVSNNSMRPSQHTSRVDRGDNQSLHELDIGPQQNRGPLGSHPHAMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN39</accession>
    <name>A0ABR3YN39_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Asl1-like glycosyl hydrolase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_005662</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000205">
        <property type="protein sequence ID" value="KAL1889776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053183">
        <property type="entry name" value="ASL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024655">
        <property type="entry name" value="Asl1_glyco_hydro_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154">
        <property type="entry name" value="ALKALI-SENSITIVE LINKAGE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154:SF10">
        <property type="entry name" value="ASL1-LIKE GLYCOSYL HYDROLASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11790">
        <property type="entry name" value="Glyco_hydro_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047522834" description="Asl1-like glycosyl hydrolase catalytic domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="Asl1-like glycosyl hydrolase catalytic" evidence="3">
        <location>
            <begin position="208"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="113"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="436" mass="46609" checksum="FC7C2046112A3E69" modified="2025-10-08" version="1">MFVKSPVASLLAATCMASSAIAANSFRHARLHRRAEANKLDARGGGTVVHWVTHTQFVYAGGTPDAQEPSAVEALNYIAEPTTTTSDVVPTVKPTSPTRNIPVVRPFTYNEVPSSSTTSDAPATTPEPDYNYVAPAAVTPKPDYNYVAPEALAVVSESSTTTSIDYQAEAVTSSSSTAATASSQADASSGSASYSGSTSSSSSSSKRGLAYNDLVLDAFFEKRSFSWAYNWGAFATGLPEGTEFVPMLWGNSDYFTKPWSAAADAAIASGSAHLLSFNEPDIAGQSDMDVDTAINAHIKHMAPYKSKAKIGSPATSNSNLANQGNIWLREFITACDANSECHVDFCVTHWYDEASAVERLYSHLEEVHEICGDREIWLTEFAPSGTDEEVVSFITTNLPKLDELSYLGRYSYFYAAVPKMLTSSKALNSVGAAYVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNG1</accession>
    <name>A0ABR3YNG1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endoplasmic reticulum junction formation protein lunapark</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_005978</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a role in determining ER morphology.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the lunapark family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000238">
        <property type="protein sequence ID" value="KAL1888934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040115">
        <property type="entry name" value="Lnp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019273">
        <property type="entry name" value="Lunapark_Znf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22166">
        <property type="entry name" value="ENDOPLASMIC RETICULUM JUNCTION FORMATION PROTEIN LUNAPARK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22166:SF12">
        <property type="entry name" value="ENDOPLASMIC RETICULUM JUNCTION FORMATION PROTEIN LUNAPARK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10058">
        <property type="entry name" value="Zn_ribbon_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Lunapark zinc ribbon" evidence="4">
        <location>
            <begin position="162"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="54"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="239"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="19"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="73"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="239"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU367073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1888934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="264" mass="28682" checksum="B130579C67B5A080" modified="2025-10-08" version="1">MDRIYLARYTVATYYDFRVDTLETRLKELQAQREKTIQKLKDATKYDSTMELLEKYGGGSKPNKSPEKSITSAADPKAKFGGAAAAPKRTNQPPPPTANINRVTSSGVSIIRNTETSTPSAQIAVSEEFAPNAFGDPASTQLTIPNPVQRTSSLQISGESHWYDRILDLLLGEDEKDPKNRIVLMCQKCRLINGQAPPGVKSLEEIGIWKCMSCGASNGKLDEGVEILDVVLKAQETVQAGSNIPSPRVNSDRTSSSSSSSSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNG6</accession>
    <name>A0ABR3YNG6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005813</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000218">
        <property type="protein sequence ID" value="KAL1889391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046932967" evidence="2">
        <location>
            <begin position="22"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="239" mass="26962" checksum="E67458905792599F" modified="2025-10-08" version="1">MEWDWGLIIKTLLCLARTARASGISPEDFFRYQAEKRYAAVQQKIERALDSGIKATRSSCPLGQESRDTTNDGDDENNDKDRNRNNSQNASEQSNGDFGGDNYEGSDEDSDVSLGSENEDSAMSSRDDPEFVICIDEAHNIVVDKIEGSELSFCTLRNGFRFLYEDEYEGTFFAVFPDTASTIPDLAPLLLQILARKSLHIIGRVERSFLLIFRFLPITSMLSQARISLWHQVHPLQCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNN8</accession>
    <name>A0ABR3YNN8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_005735</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RENT3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000212">
        <property type="protein sequence ID" value="KAL1889542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039722">
        <property type="entry name" value="Upf3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005120">
        <property type="entry name" value="UPF3_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13112:SF0">
        <property type="entry name" value="FI21285P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13112">
        <property type="entry name" value="UPF3 REGULATOR OF NONSENSE TRANSCRIPTS-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03467">
        <property type="entry name" value="Smg4_UPF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="507"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="180"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="577"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="208"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="229"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="345"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="369"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="433"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="452"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="592"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="606"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="642"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="653"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="677"/>
            <end position="695"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="695" mass="73254" checksum="0ADD999DEF94036A" modified="2025-10-08" version="1">MTAAQTKAVRPGSLTAGTTGTNANLQSSKSSGRNGRSRNQALGVMVKIRLLPPAMQEAECLRLLPEEWHVAKGKVDSFRYTPGKVSNRPGRPSHASVAYFQLSREDDVVSFGETVKLIVWEDAADTFHDPCLKAKPYLERCVYRKNPMEKDRGDSLQGTIDQDPEFIHFLENLTRVAANEKEEDKTAAQTPEVEKSTEKPTSTPLVEYMREKREKDKDAGGTGRGSRSAKQEARLAAKSSKSGDKKKARDKDRDSGKDKEKSERMTDKIKILKKAAMADAPCTSKNAAAASNGSQAPRNQSSSKTKRATIAAAARVLQRDHGLSPGAAHRRARAEIAKVEMQNKTAAAAAATTSGASTSLPSKKDSPKGSLQTPTETSKPAEPATGSSKREPGRTRGRGRGKGGGDTNAAKAQQQEPVKPIILLKKKPEIDASPTSIQSPFLKTNEAPRIAETSTKGASEPATQPTASSSKGKLAEKSNNSSKARKADRQDAKSGASAPLTVTPGATKAFIKNVNPSCGINASSLRTALSCFGAINAIDIELRKGFAYVEFSQHESLVAAVKAGSISIGQGHIRVAERKAKKPTPGPAASIAQGSSCSPSGNGSLEKTDEKNAEKTKTGDSKATGEKAEKAEKPEKPEKGSSRRNRGHRGGSGKKEKDGSRGVKDVSTGGDKGIKGSGSSAAALALGPASALAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNV0</accession>
    <name>A0ABR3YNV0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mitochondrial import inner membrane translocase subunit TIM50</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TIM50</name>
        <name evidence="4" type="ORF">Cpir12675_005743</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the TIM23 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TIM50 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000213">
        <property type="protein sequence ID" value="KAL1889526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="1" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="1" id="KW-0811">Translocation</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FCP1 homology" evidence="3">
        <location>
            <begin position="207"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="98"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="98"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="112"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU365079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="492" mass="55462" checksum="E4F6AD26B107AB06" modified="2025-10-08" version="1">MLSRISRLAPRAASNVRPSTFRPSTLAYTTRLSSSSSKDPKGSTPSYDASQQKPSAAEPEPEFHELPDLTQGIPSTFEFEQAARKKGSQNIGDELSKALSVSAAQSSQGGSGDDKSSRDSSYKSSAERKQEAVAKYSLGLVLFSIVAGAAYMGRDWDSEGEAAQHPKVPNGWGIGLWWNRVRARMTETVMYYQEPAFDKLLPILDPSLQKPYTLCISLEDMLIHSSWDRQRGWTTAKRPGVDYFLRYLSQYYELVLFTTVPSMNALPTVQKLDPFQFIMFPLFREATKYEDGEVVKDLSYLNRDLSKVIMIDTNGRRLRKQPENAIILPKWKGNPRDTDLVDLVPFLEYLATMQTSDVRKVIKSFDGKKIPEEFARREAISRAKFEKQLEARKPKSSASNFVGGLLGLKAGVNPTNPDDINPAEAFAQGKMLHDIARERGQRYYQMLESDLKANGEKYLKEQREAMEKQQQEAMNSMMGSFSTMFVPSQEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP04</accession>
    <name>A0ABR3YP04_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphatidylinositol-specific phospholipase C X domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005552</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000196">
        <property type="protein sequence ID" value="KAL1890026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051057">
        <property type="entry name" value="PI-PLC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593:SF113">
        <property type="entry name" value="SI:DKEY-266F7.9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047286648" description="Phosphatidylinositol-specific phospholipase C X domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidylinositol-specific phospholipase C X" evidence="2">
        <location>
            <begin position="43"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="364" mass="40273" checksum="1EBC7934109C73A5" modified="2025-10-08" version="1">MRFPHFIILAFVGFSYAGNFKGIEDKWSFDLGNIDHSDWMSDIDDNVLLSKLSIPGTHNSMTAAVQSSLTRTQNEHLSDQLTGGIRYIDISCRYVNNEMMVYNGVSETGFSLGDVLHIMFEFLDAHPRETLILRIQKGGILGDSKKLAQFIEQSFAPDSEIGDRAAQHIYFRNVDDISIPTLGEVRGKVFILQDFKNSQPALYGIPWNKDTVSSYSHRLASGSLFLGLKWDGVRSHLSQSHPKDINKLRITHTTASAGVKPISIAAKNLPGYGMNGLLGRYLMSDEGDCFGIIVMDFPGCYLVQHILELNNQYQAPGLHSFSLSPSAPPLPEWFDNEGFENVAPSLDASYDGDGDDTATAGLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPJ5</accession>
    <name>A0ABR3YPJ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GTPase activating factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">BUD2</name>
        <name evidence="5" type="ORF">Cpir12675_005458</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000187">
        <property type="protein sequence ID" value="KAL1890288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05137">
        <property type="entry name" value="RasGAP_CLA2_BUD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039360">
        <property type="entry name" value="Ras_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023152">
        <property type="entry name" value="RasGAP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10194:SF60">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN RASKOL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10194">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00323">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00509">
        <property type="entry name" value="RAS_GTPASE_ACTIV_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="3">
        <location>
            <begin position="695"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GAP" evidence="4">
        <location>
            <begin position="900"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="128"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="272"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="318"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="509"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1262"/>
            <end position="1303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1318"/>
            <end position="1339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1376"/>
            <end position="1449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="31"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="274"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="318"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="355"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="509"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="534"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1264"/>
            <end position="1274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1289"/>
            <end position="1303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1429"/>
            <end position="1449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1890288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1449" mass="157483" checksum="95CE9D6C07912C74" modified="2025-10-08" version="1">MDGKLPTANFKASILHAKKPDRESPVPIRASTFGTTTTITSNSGSITSSSPSRTTIINAANTSDITSSSSKELTSAASTVSTTSTAATTASPSSKRSRLSAQPHPPSSSIPIAPITRKAKIPLVIPSAISDSPAPQDASNFLVDGDESPEGGRRQGIVFHESFQATPLPDTNVKPKYPSTYGDAALLVTVPPTAAIATASISASPAPSPSSSSPSIVPLIPHLSTVVSSSASLPPIPSRCKLLRQRTSTLDGSFMRQTSALGGLSTMADHRSRVGSFSATSSSSLSMQDDPQHPPGSGAESLGYPSIHTGPFPFPLSLPLSKSTSSSKSSSQLQPQLAQPSTSTTSPSSRDKKSSSAKRRIKRSSSRPTSPVVTTPPCIDSLSIPIATTNANKILLLMKTLCGRMRGDIEYQTEAGGPWYRGVSWIEEDQGCLMFDSGHTKGIVLTLCADLRGSRIVPVLDPENGRTCLDLITGFPLMDILIRPCVDEEVDLWIAALLCWQQVSLAPSKHSGGSSAGSNNHNSSRPELRRRGSSLAQNHNVSAQGKSPSIIKVAKVHVWDKGFPKSPREIFKSPSPLDSRATKDNKDHSWARVSCLLQDNGELQLLSENDVSVLTLIDLHQLSRSAIQRMDCTLFDDMEFCLAIYPMYAPGSSHLSIFRPIYMSFESHVIVDVWYVLLRAFAQPRLFRYNSQSLGPPELVTDIESSTHGEIFRIERTLKVRIVEAKLKDHASASEKSGHGHSRHNTGVESVVGNYFVEVLLDGEIRTRTAIKHSTKNPFWREDCVLADIPPSPPLLSIVLKRIDGLEVEKKIHFSKPCSPSERWCGTVDIPIDQMEMADEHEHWLPILNANNQSIGTMLVKIHHEEMAVLLTSEYESLRELLQRFPSGLTSQIARQIPGGLRRLAEVTLDIFQVSGKVHEWLMSLVEEEIDGITNQAPVKNYRFSSRLRSNESIDFGIDREQLVRDMSKSLAGEANLLFRGNSLLTQALECYMRRLGKGYLEEVLRDKIVEINEMNPNCEIDPSKLESGDDIQRHWALLIKLTTEVWACISQSANQLPTEMRHILKYVRAVAEDRYGDFMRAVSYTSVTGFLFLRFICPAILSPKLFSMLRDLPEPRAQRTFTLIAKALQAMANLSTFGQKESWMEPMNKFLNSRRASLKLYVDEVCSIPADQAIPLLPPSYSTPLAIMNRLSATAREGIPVLPHLVDPTRSLATLVSLWSNANSSSNSDQPGGDIALFNSTCQVLQHRAAACLKNAELLREPTATSSSQSTEDIPSADGEDELSGVVSSNIPSNRSTSSLGSLSGMWTLTRTERSVEHLRAPSSAGSDVLETASSRRRLNSTRDAAADLASGTGFGALGRLDIQSLAQLQLQTQAQRGSGWPSSAPPMSPIGTLRGSRNGRTTRNILSGIIRMGRGGETGSQAQAEAGEEKDTGKAKAEKESGKNKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPM8</accession>
    <name>A0ABR3YPM8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA-directed DNA polymerase</fullName>
            <ecNumber evidence="4">2.7.7.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Mitochondrial DNA polymerase catalytic subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">MIP1</name>
        <name evidence="15" type="ORF">Cpir12675_005816</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA polymerase type-A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000219">
        <property type="protein sequence ID" value="KAL1889354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08641">
        <property type="entry name" value="DNA_pol_gammaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.390">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019760">
        <property type="entry name" value="DNA-dir_DNA_pol_A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002297">
        <property type="entry name" value="DNA-dir_DNA_pol_A_mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001098">
        <property type="entry name" value="DNA-dir_DNA_pol_A_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041336">
        <property type="entry name" value="DNApol_Exo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047580">
        <property type="entry name" value="POLG_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10267">
        <property type="entry name" value="DNA POLYMERASE SUBUNIT GAMMA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10267:SF0">
        <property type="entry name" value="DNA POLYMERASE SUBUNIT GAMMA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00476">
        <property type="entry name" value="DNA_pol_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18136">
        <property type="entry name" value="DNApol_Exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00867">
        <property type="entry name" value="DNAPOLG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00482">
        <property type="entry name" value="POLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00447">
        <property type="entry name" value="DNA_POLYMERASE_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 15" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 15" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase family A palm" evidence="14">
        <location>
            <begin position="697"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1075"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1075"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1099"/>
            <end position="1115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1889354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1196" mass="134424" checksum="F1BE7A1D9D85B6ED" modified="2025-10-08" version="1">MSIFSRNLIAHRAPLRISPPSNLRIVSRRLPAFTAILRCASTKAATEKEIKTLALPATTRTNEIGIQHISHEMHKQIFPNGPATKVPQELVELAKLHLTKHNLLGKNTDENGPIAFEVPELVGKSKTLDEHFTRLGIDCAEPYLTKAKEFSICGYPRKPSKWVQVSGWVKYTRDEDGREVHQVVDAPDDDCLCFDTEVLWKESPYAIIACAMSPTHWYSWLSPWLLGESDSPKHLVPLGDPSKKRIIVGHNVGYDRARILEEYDKKQTNNAFIDTMSLHVAVNGMCTQQRPTWMRHRKNRELRERMLENPEDVELAELIKSRTQEEEEELWVERSSVNSLRDVAQFHLKLTMDKSVRDDFGTLNRQGVVEKLQELMDYCAADVQITHKIYRIIFPNFLEVCPHPVSFAALRHLSSVILPVDQSWQNYIQTAENTYQAMNEGVQKRLIELAHKALEAKDNSEVWSKDPWLCQLDWSGQEIRMAKGKKKNDPPRPAANQKMPGMPKWFKDLYLKASGPINLTVRTRISPILLHLCWDGHPLIWSDKYGWTFRVTKKEANTYLAKQMVLCDFSEGEKVQALIDDKTGCYFKLPHKDGPNSRCTNPMAKSYLPYFEKGILSSEYPYAKEALNMNASCSYWISARDRIMSQMVVYEKDFKGEKADGEQGYIIPQIIPMGTITRRAVENTWLTASNAKKNRVGSELKAMVKAPQGYSFVGADVDSEELWIASLVGDATFKLHGGNAIGFMTLEGTKASGTDMHSRTASILGITRNDAKVFNYGRIYGAGLKFAATLLRQFNPNISEQETMDTASRLYANTKGTKTNRKVLHKRPFWRGGTESFVFNKLEEFAEQERPRTFVLGAGITEALMGRFISKGGYLTSRINWAIQSSGVDYLHLLIVAMDYLIRRYSINARLSITVHDEIRYLVKNEDRYRAAMALQVANLWTRAMFSEQVGIPDLPQSVAFFSAVDIDHVLRKEVDIDCITPSHKTPIPHGESVDIETLLAKGKLAYLDPNITPDPLVAPKPENTAFSPRSSVMAGMKGAGSYDEHVTFLKAQIIDSDKELEDLVKQRVKKRSVASALAKSATSTSGGSGSKSRDAATVPSNASDSTGIRTQDGSKGSAYATTGIKPGPGRPVSLKNVIPYHATPKMMPTKNPIVFYNSVNSFNYRSNKFANKPGSSPSARSDTPKFIPFYDGFRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPV9</accession>
    <name>A0ABR3YPV9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PAK6</name>
        <name evidence="13" type="ORF">Cpir12675_005595</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000200">
        <property type="protein sequence ID" value="KAL1889927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06609">
        <property type="entry name" value="STKc_MST3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050629">
        <property type="entry name" value="STE20/SPS1-PAK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012:SF10">
        <property type="entry name" value="FI20177P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012">
        <property type="entry name" value="STERILE20-LIKE KINASE, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="19"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="338"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="501"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="717"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="423"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="439"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="501"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="553"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="578"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1889927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="737" mass="82107" checksum="67303E3B31AA53CB" modified="2025-10-08" version="1">MADRSHDERNEALDPELLYSKEYCIGGGSFGKVYKGVDKRTGQPVAIKVIDIESAEDEVEDIIQEIAILSELQSPYVTKYYGSYAKGAELWIVMEFCSGGSCADLMKPGLIGEEYIAIIMRELLLGLDYLHSDKKLHRDVKAANVLLSSNGQVKLADFGVSGQLSATMTKKNTFVGTPFWMAPEVIKQSGYDHRADVWSLGITALELANGEPPYADIHPMKVLFLIPKNPPPRLEGSFTKTFKDFIEVCLQRDPKERPTARELLRHPFIKKAKKTSYLTELIERYSRYAATHKTDDDDIMNSHEDNVVASSMRVDEDMWDFGTVRLVSDRGNIVHRPDLDAIAGPTANSRPSRPLEPENRLGNRAASPSKKRDYDLGSSDTVKVDGTMKQSSPQRKPLQPVLNLVSSSPTKPYYPPPLPSPTRVTVQPPTRIETPTHSNRHDPVSIHQSPDYDRVLQEELQRDLDSMNLASAIQPSNHHNHNQNQPPPVPVHSNRILAEAQNSQSQTRQQVNHSPSQPTNSHALPQPSSRAPKLAPLSLAEIPPFRGPPTPQHVPQQLKQAQPQFSHHQKSRDITPVTLPNKTSAPTHGLQSKAQLPSEPLTPSSFPPPASPSSNGELDALNDVIFPALEEALKRRQIRLQQAFRPNGQVTPRQQRSEAAHEKVRKLVYKLAHVCKEIDHYDKAEPVGMGRDVGTFLEGLLEEILVRVEPLDEEEVAAVAHQQQQQPHHQQAGLHGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQG8</accession>
    <name>A0ABR3YQG8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Target of rapamycin complex 2 subunit AVO2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005327</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000179">
        <property type="protein sequence ID" value="KAL1890575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24183">
        <property type="entry name" value="FIBRONECTIN TYPE 3 AND ANKYRIN REPEAT DOMAINS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24183:SF1">
        <property type="entry name" value="FIBRONECTIN TYPE 3 AND ANKYRIN REPEAT DOMAINS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="164"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="249" mass="26731" checksum="90B08F479578FCA0" modified="2025-10-08" version="1">MLQAPPPKMLPRQAPTILTPSIRLRRAIHLNDACLVSRILRSHPHLLHNPDPSTEGRSNTNLHLAASLGYLAICEVLLAAGHETPSPALNEDHQTALMLAASKGHTDVVHLLAEYAPSSIIRRDKHGRDAVMEASLAGFDTDLQILLTYAPGGPTSIVQNEDADGNTALHFASSSGNLLVLRTLLAAGADVNKQNLQCWTALSYSATVQTEVYLKTLVTDVEKKKKQQAINEGEGVKKGMAMRLMGGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQR6</accession>
    <name>A0ABR3YQR6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha tubulin suppressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ATS1</name>
        <name evidence="5" type="ORF">Cpir12675_005271</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000175">
        <property type="protein sequence ID" value="KAL1890691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051553">
        <property type="entry name" value="Ran_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982:SF5">
        <property type="entry name" value="RCC DOMAIN-CONTAINING PROTEIN ATS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="RCC1-like" evidence="4">
        <location>
            <begin position="3"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="134"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="192"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="286"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1890691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="386" mass="40254" checksum="EDEA260DA41FBEC1" modified="2025-10-08" version="1">MAIFALGSNGNGQLGIGHFEDVSVPQLSLFASSPDGGLEILSAAFGGNHSLLLLKSPIPSYIEHSSPPGACVYCSGLATTGACGLNSPADKVANFRPLMAFASTTSVDSRELDSATPTHIAATWEASVLVFDRVRVYTLGSGSKGELALGSLPAEIVRSASATRVPDFPPSGTEIVDLVASMAHVLAVLDDGRVFGWGNGRKGQLGEPADAILKSPRQVLVAGDTDFKAIRAVAGKEFSVLLDARGRVAVLGGEKWGIKSSAPTVLLDCIDIRAGWGNVYALHADGKLTAWGRNDHGQLPPADLPAISRIAVGSEHVVCLTKEDKDVISWGWGEHGNCGPGVDDKGDFKNRYNIIASHKNVTAEAEIGCIAAGCATSWINITSVKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQZ3</accession>
    <name>A0ABR3YQZ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Vacuolar protein 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">VAC8</name>
        <name evidence="11" type="ORF">Cpir12675_005471</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 10">Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Vacuole membrane</location>
            <topology evidence="1 10">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the beta-catenin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000188">
        <property type="protein sequence ID" value="KAL1890278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045156">
        <property type="entry name" value="Vac8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47249">
        <property type="entry name" value="VACUOLAR PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47249:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00514">
        <property type="entry name" value="Arm"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0926">Vacuole</keyword>
    <feature type="repeat" description="ARM" evidence="9">
        <location>
            <begin position="99"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="9">
        <location>
            <begin position="140"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="9">
        <location>
            <begin position="181"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="9">
        <location>
            <begin position="222"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="9">
        <location>
            <begin position="265"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="9">
        <location>
            <begin position="306"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="9">
        <location>
            <begin position="347"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU369097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1890278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="570" mass="62150" checksum="5B3D9F00527C761E" modified="2025-10-08" version="1">MLSRSDVLRFASTNPGSLFLLSGRSGDSLYDPILAENEREAVAELLQYLENRGDTDFFSGEALGALSTLVYSENLDLQRSASLTFAEITERDVRRVNQATLKPIIYLLGNVDIEVQRASSAALGNLAVDPDNKVLIVQMDGLPPLIRQMLSPNVEVQCNAVGCITNLATHEDNKATIARSGALAPLTRLAKSRDMRVQRNATGALLNMTHSDENRQQLVNAGAIPVLVQLLSSPDVDVQYYCTTALSNIAVDSNNRKKLAQNESKLVQSLVNLMDSGSPKVQCQAALALRNLASDEKYQLEIVRSHGLQRLLRLLQSSYLPLILSAVACIRNISIHPHNESPIIEAGFLKPLVDMLGSTDNEEIQCHAISTLRNLAASSDRNKTLVLDAGAVQKCQQLVLDVPLSVQSEMTAAIAVLALSDDLKPDLLNLGVFDVLIPLTYSDSIEVQGNSAAALGNLSSKVGDYTIFVQNWFEPNGGLHGYLDRFLQSGDPTFQHIAIWTLLQLIESEDKNLISLIGNSEDILNEIKAIANRIPDSECEDDDDEAEVITLAQRCLELLGHSLPKTHIEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR34</accession>
    <name>A0ABR3YR34_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphatidylinositol 3,5-bisphosphate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">HSV2</name>
        <name evidence="6" type="ORF">Cpir12675_005631</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat PROPPIN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000203">
        <property type="protein sequence ID" value="KAL1889834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048720">
        <property type="entry name" value="PROPPIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11227">
        <property type="entry name" value="WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21032">
        <property type="entry name" value="PROPPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="289"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="293"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1889834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="421" mass="45464" checksum="E6C2E38296DC2140" modified="2025-10-08" version="1">MDVRPQIEPAVATQVLSASFNNDRSCFAVGLNTGICMVADQSFFSLPYKVVLDESIPRYAIYSVSLWFEHTANDVAIILDFNAGIGLVQMMNSSNYLALVGGGRQPKFSNNKVIIWDDMRGSIALEISSLTPVRGVKLSRTHIVVVLQNRVSIYAFKKNNPILSENETVDNPLGVCALSDHHVAFPGRQAGHINLVDLKELNVSIIPAHSSSLRDLQFSPDGEMIATASETGTLIRVFSTSTGARVAELRRGIDPARIFSIAFSPSGTLLACTSDKATLHVFDIPHPTRSMASKSPSPSGLPLSSPTSLLPNAGDGSGRGKWGILSRLPLMPRAFSDVYSFAQAPFETGDESLVGGLPVSETTTLGTTRPAKGLIGWISDESIVVIGAGHDARWEKFSLSVGQDGRRQLLRDNWKKYLGHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR54</accession>
    <name>A0ABR3YR54_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cochaperone prefoldin complex subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">GIM4</name>
        <name evidence="4" type="ORF">Cpir12675_005438</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000186">
        <property type="protein sequence ID" value="KAL1890362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23163">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027235">
        <property type="entry name" value="PFD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002777">
        <property type="entry name" value="PFD_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13303">
        <property type="entry name" value="PREFOLDIN SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01920">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="9"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="80"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="115" mass="13225" checksum="E1CA83486F1FE558" modified="2025-10-08" version="1">MSVQTSKKQSDLQAQYSNYKNTLQQLASKIGEIEQDTEEHKLVLDTLEPLPGDRKCFRLINGVLVERTVEDVKPLLKTNAEGLAKVLEDLVKQYKLKEDELQKWKKKNNVQVVQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR83</accession>
    <name>A0ABR3YR83_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005233</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000171">
        <property type="protein sequence ID" value="KAL1890808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216:SF65">
        <property type="entry name" value="PAXILLIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216">
        <property type="entry name" value="PAXILLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="466"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="569"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="607"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="714"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="851"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="964"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1059"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1183"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1253"/>
            <end position="1376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="626"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="714"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="735"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="754"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="772"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="803"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="898"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="983"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1061"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1072"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1202"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1219"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1257"/>
            <end position="1280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1287"/>
            <end position="1302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1312"/>
            <end position="1321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1338"/>
            <end position="1350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1363"/>
            <end position="1376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1376" mass="149497" checksum="C21C7740EAEDE1D9" modified="2025-10-08" version="1">MSASDSQSMSRPSSAMASPRVMRSRTQSFSSDRPSAYSASSLSMMFPPLKISPEAAFIAESAASQIITNDHDTHADTWYDQNGVEPSSEPAIVTPGALKLVNTFLDQLLFNFLHRARGTSLSALRPAVAEVLKPKLAKDAINLADEELREYLGGGSEEGLSGEESFNTNSDWDQELVWKRTRLRCMVYSSLGDLEEEDEDFFLEQDGLDICDEGNEVVSPAVAIFLTSILEFMGEQALVIAGQASYQRVCAKFEKNLRDGTRKHSDTADRISVEELDMERVALDRTLGRLWRAWKKRIRTPAHESPREPRDAFKGNHTRHASNSLSEPAVVKEVNPRPEIEVVPPEVAILSPESVPLPINDNDVNEIEVPGLVSYSEDEKSVSDDLLTTSAAILRPKSFMMLPSSKRLSFFTPVLFADDVSMEPRKRSYSLPSPEPAPFAFVGTDNVEFVGPDQVQIREPVVNSVKEEAPEAAETQLTSEPAVSREEPPSSIEKGSLDSQADRPQASLPASPVSSKRRSRVLQSPLVIQTSIPVTHRTRIDHKDITLEDDELDELEEEPEILTSARVSISTGSASPNLSDTTRGFNSQGVQRTNSVHSARIIEVTGPKSPVASRASSIDTLERVRTSSVSHTSSVSASPIMEEQEPSMACASPGPPPRNPERVTRNAPINKLAIYNNDSEQPRIKHTEILAPHIAAAMAQSPTIPQEYFRAPAQASSPLANSNSHHSPRVPQFMDASSSATPGPSKSPVLGQAKIDDASLDRSYRPSAPALRSQTKITPIQEHPSPTSTSSFEDKIPPRPIHTSGSAGSATGSRLKLVRTSEESNLGKAEDMAKNFEELIQSDQTIQYTLTPEGMRDIDSPRSGSPAMPRTPRRANTAGELTFSRSESNSPEPPRKASVSSAHTAQPNPLLSHPIQPQTSAPPIIPVKATAAPLVAKPRVMNTMARDARAKRDSTMDFADFIRSTGPPGGDNPPMRPNAAVGRSSSMRTTNSASTRLYTSGSIDTSKRHRLMARDAAVDSRENNSDLIDFIRRGPPSAMGGGTIAVTPRPGVSAIVTPRTKLMDSDSELRKSQGSARGTDVSVNSSVTSQSALLKRSAGYSNGTFFDSGDMPIPQRKTRRVRDPYAIDFSDEDDFMDEVESSAPEPRAKPVPAREESLADFLRNYEPPPAQPVVPLSVNATRTQVAPPKKKSSMPGLIGRFSRNNSNQNNSTPNINVNESRSLNSRSGSVVTSYSGRGYIPIQVNMPPGYDKYGLVDTSSNASTARQSRPSQSSAHSFTSAGRRPSAASTGYSMTADNNSSGIAPPRRTPMKRYEPREPLHISRATGTSELAAFLRSSEPSPGMMNSRTFSPVPPPEPEASSHRRIFSRRKKSVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRW1</accession>
    <name>A0ABR3YRW1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">coproporphyrinogen oxidase</fullName>
            <ecNumber evidence="4">1.3.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">HEM13</name>
        <name evidence="8" type="ORF">Cpir12675_005108</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aerobic coproporphyrinogen-III oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.3" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000163">
        <property type="protein sequence ID" value="KAL1891100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1500.10">
        <property type="entry name" value="Coproporphyrinogen III oxidase, aerobic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001260">
        <property type="entry name" value="Coprogen_oxidase_aer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036406">
        <property type="entry name" value="Coprogen_oxidase_aer_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003727">
        <property type="entry name" value="PRK05330.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755">
        <property type="entry name" value="COPROPORPHYRINOGEN III OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755:SF0">
        <property type="entry name" value="OXYGEN-DEPENDENT COPROPORPHYRINOGEN-III OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01218">
        <property type="entry name" value="Coprogen_oxidas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000166">
        <property type="entry name" value="Coproporphyri_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00073">
        <property type="entry name" value="COPRGNOXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102886">
        <property type="entry name" value="Coproporphyrinogen III oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1891100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="338" mass="38386" checksum="4267C9D2CEB89956" modified="2025-10-08" version="1">MASQETLAQQDDRIRSSGVNSESPLRLRMEQFIRGQQAEIVAAIEAVDGGSVKFRRDDWQRPEGGGGTTCVLQDGKVFEKAGVGVSVVYGMLPKAGIQRMRVNHKSLVADDVESLRFFAAGLSLVFHPKNPMAPTVHLNYRYFETCNDDGSGGAWWFGGGCDLTPSYLFDEDAEHFHRVIKKACDKTNASYYPRFKKWCDEYFCNKHRNEARGVGGIFFDDMDAAEGDPEILFGFVQDCLKAFLPQYLPIINRRKDMPFTEAEQEWQQIRRGRYVEFNLVHDRGTSFGLNTPGPRVESILMSLPLTASWHYMHEPEEGSREAQLVEVLKNPREWLANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS82</accession>
    <name>A0ABR3YS82_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_005065</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Endomembrane system</location>
            <topology evidence="5">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000160">
        <property type="protein sequence ID" value="KAL1891219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052606">
        <property type="entry name" value="DnaJ_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44653">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44653:SF2">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0732">Signal</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045871047" description="J domain-containing protein" evidence="8">
        <location>
            <begin position="20"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="9">
        <location>
            <begin position="44"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="214"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="350"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="239"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="419" mass="46488" checksum="66234B12A0785998" modified="2025-10-08" version="1">MKFSSVCVGLLALLSPVTAMWSKEDREIFRVRAEIQSAEGAHVTFYSYMGIEPNATPDEIKKGYRKMTRMLHPDKVRQRLFAEKKAAAAQNKKDGKSAKPEQPARSEISKAVKIASQKQGRLTVVNDILRGPGRDRYDHYLANGFPLWKGTDYYYTRYRPGLGTVLTGFFIVVGGGFHYLALYMSWKRQCEFVEGYVKFARDTAWGDVANRPIEPVAPAQPEEPEADAAPIPRNRRERRFMEKQEKNEGKKPTPKRRSAKPAAVTVGGDEEEEVEAGPVGARRRVVAENGRILVVDSLGDVYLEEQDEEGNVNMFLLDPEELLPPTWRSTAVVRVPAWFLSIITSRIGLGSSKSNPSASSKASSENAGNGLLSDEPQNTPDSGSDFEMVDKSVDDIGNTKSSGVQSEGGAKKRKANKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSB9</accession>
    <name>A0ABR3YSB9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prenylated Rab acceptor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">YIP3_2</name>
        <name evidence="2" type="ORF">Cpir12675_005057</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000160">
        <property type="protein sequence ID" value="KAL1891211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="285" mass="31259" checksum="9CCA9DD48E682747" modified="2025-10-08" version="1">MSTRPGSGDDEATRSRQGLASGSVAGTRATSRGRVVEEIESGDEEGSQGTLARRSDVLGLAYGDDSGLYDSYDEDYSEDDLDPNMPQEERDEILVESAMRRIQDAQERGSSDVHLSSKELAALERHKKRMEEERVRKRARRREREQQRVAVPISQLSFDFASRSSASSPEPSEYSSRSGSSTYPPNSASMKKRSGTQRQSSVGARDREAYEQSRSTASSRSKAATAGSFKDMRPVTPGSIAANATPPASARNSPNSADNDERSTRRKTRSSTAANSTHESSRRHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSX3</accession>
    <name>A0ABR3YSX3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CHCH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005149</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000165">
        <property type="protein sequence ID" value="KAL1890992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039870">
        <property type="entry name" value="Coa4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13639">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 4 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13639:SF2">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 4 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="82" mass="9643" checksum="443F12022E3A02BE" modified="2025-10-08" version="1">MASKPDKEIVTQQNVMDTVETEDEPDPWDVRINNTGCAVENSRLTDCFYETKDWRKCTTEMMNFQNCWKKNNNDVRTSMKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTC8</accession>
    <name>A0ABR3YTC8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Serine/threonine-protein kinase</fullName>
            <ecNumber evidence="11">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SCH9</name>
        <name evidence="11" type="ORF">Cpir12675_004997</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="11"/>
    <dbReference type="EMBL" id="JAWDJO010000156">
        <property type="protein sequence ID" value="KAL1891347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="443"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="10">
        <location>
            <begin position="705"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="209"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="303"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="787"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="63"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="219"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="333"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="804"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="472"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1891347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="856" mass="93749" checksum="55BF7B896363F7E7" modified="2025-10-08" version="1">MSIDDGSVGVHPLPLPSPDTPNPSNAPNTPVIPTLPLLPSKSSAQLPPSPAPTERPIEKPLKRSQSPDPSWPSNNTKTRSSPHRNNCSLGRELRAPSNRLASFAKSKSSSQVKSALVEAVVSTKMVEVEPILHFKDISSQASQGNMSKLASIVSTAKMAAEASTQTTLALAGDKSVSPKIQRPTLQSQESCGSGWTIAENIKRLTNFLKSGPPTPRALSVSTPLEQTLKIPNNNRGSDSSNAISRSATPKPASSTGAPAVAKGKLKVRIVEARSLGRCREPHVVAVFQRSQLISGAAHSCEPGMAAGPPLNRPIPMQRTGSSQGRFPHGVPMQSRQSSNSSATEAKVGGSRKSLTNIKWDAQAIFDVVNSDTKLDISVYERDDQGNDIFYGHVTFDTRADKQESIKGWFALEGHADTPAPTGEIYVEANYQRAERKHLGPSDFEILRLIGKGTFGQVYQVRKKDTQRIYAMKVLSKKVIVQKKEVAHTVGERNILVRTAMSDSPFIVGLKFSFQTPSDLYLVTDYMSGGELFWHLQKENKFGEARAKFYIAELILAIQHLHENDIVYRDLKPENILLDANGHIALCDFGLSKANLTKNDTTTTFCGTTEYLAPEVLLDESGYTKMVDFWSLGVLVFEMCCGWSPFYADDTQQMYKNIAFGKVRFPRDVLSAEGRSFVKGLLNRNPKHRLGAHGDAEELKAHPFFGDINWDQLARKLITPPFKPTLKSDTDVSYFDPEFTTALDNNGSLNARAAALARGIATSTPLSPSVQANFQGFTYVDESALEENMGDGGRGHGLYNRYDNDESDEDDAHSDMDDGWDNLSDLNLQRNRNRMSGVEHGSNDDDMLDGQPFDPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUI3</accession>
    <name>A0ABR3YUI3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_005179</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000166">
        <property type="protein sequence ID" value="KAL1890989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="255"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="323"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="371"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="100"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="149"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="183"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="212"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="236"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="325"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="337"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="372"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="437"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="455"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="477"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="528" mass="56447" checksum="1637894CC44D43EA" modified="2025-10-08" version="1">MSYADAMIGGRDSFDRRSYPHHQPSPSAAPTSEEKYRVSTRLPELSSLLNTTNNGPLPSGADANAHNSPVHSPPVPLHRHHDHNPRSSWNMSQYQQRPPHGSEAEGREMTRPYDQNPYGPRPAPGPGLPGPAPPVEQPGYAAVNQHRPPGYPRQPYPHGPLPMHQPPQHEQERNPNYGYPEPSCTPPPPSNTAPPSYPSGPYTMPAPHHMAQQDQQPHQGSPSVMPVGHYPPQPSMPQAAPQPQGQPPRQRTSIACRYCRKRKIRCSGYANSPGGRCMNCTRMNQECVFQPVSSTGTNAAFVHISALQGTVPVGTPVFGAYGQLVHQSPPQNSSRPDGPPNTTGPPPPSQQPPQQHPSYYSSNEAAYRMRHTQNGPSSTGSLSPSRNNKRSTSPNIPEGHDRRMPPPPADPRAGPLRSGIQPRPPGGIESGFYAPRGSPSMSSASMSHHGSPSMGPLPPTTAPSAFPPMGPPALGYAAGSHSNSSGSPAPSPPPAPSSSVMKVSSLLDDNNKSVDRGMLNRLGRGGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUL6</accession>
    <name>A0ABR3YUL6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004802</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000145">
        <property type="protein sequence ID" value="KAL1891797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="174" mass="18426" checksum="11F43CBC50374CA3" modified="2025-10-08" version="1">MADHPDRVPPPGTTRTRAVGTSGIRRNLFTGSVARRPTSSSTESSASAASANDENARLAPALGSVSNGNGNSVNMTRYSNAVASTPTSGPATVGISQFGNVLEPVQSGQLVVRDKNGEVHIPDTTVDDEADLALQERADKENELLAEVKASLRNRVAALEDDEWMFVSTKNIHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUX6</accession>
    <name>A0ABR3YUX6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Metalloendopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">OMA1</name>
        <name evidence="9" type="ORF">Cpir12675_004647</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000136">
        <property type="protein sequence ID" value="KAL1892179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07331">
        <property type="entry name" value="M48C_Oma1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.10">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051156">
        <property type="entry name" value="Mito/Outer_Membr_Metalloprot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22726">
        <property type="entry name" value="METALLOENDOPEPTIDASE OMA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22726:SF1">
        <property type="entry name" value="METALLOENDOPEPTIDASE OMA1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M48" evidence="8">
        <location>
            <begin position="117"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1892179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="340" mass="38838" checksum="790E595A1EFA4571" modified="2025-10-08" version="1">MNPNQLPEDPPEEESVSPQQRLEMLHRYRLSQARPLFTYERAKSTARSPVTWSFVACCVGAAVIFYALNTQIVPVSGRRRFNYYGDGGGSVVEQQVKRIEYEVEHQGGSFLPDWDPRTKMVKKVMRRLIPVSGMPQETEWEVRVIHDPNTLNAFVLPGGKVFVFDGIFRVTRNEDGLAAVLGHEIAHNLAQHFGERQSSVMGTNLLMYSLLAMSYVVPPLFFAAAWFLPGMLDVVFQMPMSRVQESEADYIGLMIMAEACYDPREAVEFWRRMDYVSKRNSERDLPEWASTHPSNENRIKSILDWLPKAMDKRQQSDCKGQTSTFANMFMDALNRGVLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW55</accession>
    <name>A0ABR3YW55_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Endo-beta-1,6-galactanase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004581</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000133">
        <property type="protein sequence ID" value="KAL1892295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039514">
        <property type="entry name" value="6GAL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039743">
        <property type="entry name" value="6GAL/EXGAL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42767">
        <property type="entry name" value="ENDO-BETA-1,6-GALACTANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42767:SF1">
        <property type="entry name" value="ENDO-BETA-1,6-GALACTANASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14587">
        <property type="entry name" value="Glyco_hydr_30_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046342760" description="Endo-beta-1,6-galactanase-like domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="Endo-beta-1,6-galactanase-like" evidence="2">
        <location>
            <begin position="22"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="484" mass="52964" checksum="B56A96BDB14D1718" modified="2025-10-08" version="1">MSAAMLLSTLLAASTLQLAAAEVKIKVDPAITYPGWEGWGTSLAWWAAVFGDRDDLADAFFSLKETKLNDQTIPGLGFTIARYNAGACTKNQVNNVGINITTNMIPSRAMEGFWLNDESADINSASWDWEVDKNQRLMLSKAVERGVTHTELFSNAPMWWMLENLNPAGGNDGGNNLLPEYFAKHADYMAAVAEKAARDWGVTFTTIEPFNEPMANWWKGPTGTQEGCHIDRDSQAKIIGHLAEAMKKRSITKSTIAASDENHFQETVDTWKAIGPTAQGQITRINAHGYQAAQNDARKELWKIASEAKKDLWTSEHGENDATGSRMVNSIMLDLRLMHPNGWVYWQVLDGGGWGLIDADNEAKTIKGATTKYYALAHFSRHIRPGMTLLETGSDSVVAAYDASTKKLAIVAANFGETDTFSFDISSFKNVPAAGTVVPAWETILADTGARYASNTKNTISGTQFGASLEKNSVQTFEIEGLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXU9</accession>
    <name>A0ABR3YXU9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Membrane protein tms1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TMS1</name>
        <name evidence="8" type="ORF">Cpir12675_004233</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TDE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000115">
        <property type="protein sequence ID" value="KAL1893214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005016">
        <property type="entry name" value="TDE1/TMS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10383">
        <property type="entry name" value="SERINE INCORPORATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10383:SF9">
        <property type="entry name" value="SERINE INCORPORATOR, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03348">
        <property type="entry name" value="Serinc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="305"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="414"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="458"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="382"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="393"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="487" mass="53031" checksum="9E99E903CF252C89" modified="2025-10-08" version="1">MGAVASVPFMALPAAGTLMSFMGSCCGAATCSMVCSAFGKCGNSIATRIAYAIILLINSILAWIMLTPWAIEKLEHVTFDYVTITCPNGQCHGWLAAHRVSFSLGIFHLILCGLLFGVTSSKQPRAVLQNAFWGPKIVLWLLFIVVSFLIPDTFFIFWGNYVAMVGGMLFLILGLVLLIDLAHNWAEYCVEQVEQTGSRLWRTVLIGSTLGMYVASLVMTIVQYIFFARGDCSMNQAAITINLLLWLIVSFVSVHPVVQGYNPRAGLAQSAMVAVYCTYLTMSAVSMEPDDKHCNPLVRAQGTRTTSVVIGAIVTMLTVAYTTTRAATQSLGFGSSGSGGAIRLSDDEHDMVVTSQPSVRREMRANALRLAVEQGSLPASALLSDDDDDDLSDTSVDGSGSSGVRDDERTSTKYNYAGFHIIFFLATCWVATLLTMNWQDDTKNGDFATVGRTYAASWVKIVSAWVCYGMYAWSLVAPAVWPERFDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXY9</accession>
    <name>A0ABR3YXY9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000120">
        <property type="protein sequence ID" value="KAL1892940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="81"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="257" mass="28294" checksum="363833C06F8CFABC" modified="2025-10-08" version="1">MATDSQITISYLPPTDLTAYQREIPAAKQPLIPAIFHDSMVVRTDVFITEQNVPPESEFDADDPRSCHLVAYDTVKDADGITARKVPVGTVRIVPFPHAPHPTPEESYWSGVLKTDDPAQTGPAATPSTHHKIKVDRNGMALVDRATNMHDGREPYFKLGRLAVQKEYRGKGIADALVRTALKWISENATSFGSALVLTSEGSGESLKFKGLVCAHAQVKAIRSWARWGFIVDEEMGTWNEEGISHVGMFQRVPVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0I7</accession>
    <name>A0ABR3Z0I7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">LSM complex subunit LSM5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 11" type="primary">LSM5</name>
        <name evidence="11" type="ORF">Cpir12675_003786</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">LSm subunits form a heteromer with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000095">
        <property type="protein sequence ID" value="KAL1894144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01732">
        <property type="entry name" value="LSm5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033871">
        <property type="entry name" value="LSm5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20971">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20971:SF0">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="6"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1894144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="84" mass="9130" checksum="E6D1ECB114BB65F2" modified="2025-10-08" version="1">MASQLLPLELIDKCVGSRIWVIMKGDKEFTGTLMGFDDYVNMVLEDVIEFDYSGNHTKLPKLLLNGNNVCMLIPGGEGPVAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1H1</accession>
    <name>A0ABR3Z1H1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ras guanine nucleotide exchange factor A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_003896</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000100">
        <property type="protein sequence ID" value="KAL1893878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00882">
        <property type="entry name" value="Ras_like_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06224">
        <property type="entry name" value="REM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF348">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR RASGEF, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G04700)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="5">
        <location>
            <begin position="636"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="4">
        <location>
            <begin position="867"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="246"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="484"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="589"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="10"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="272"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="555"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1893878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1127" mass="125294" checksum="1F6D4C6C73929109" modified="2025-10-08" version="1">MDSRAHRRSVLSQKSSSESSGSHTTASRSTHRSLVFDHESSLFISPALSPASIADDSCADSIWFLDLDSPSLPPDLPAVPHHTDYRKPSFRHSALHHNNSPSYNAKTAHSRAQSDAHACDRTKLSVHPPALHSNRESFVSIVNDPFFQSLQLGSSPDAPSLDSIAQTIAIEEAHRARDKQLDIAYTTSFIDTEPDPDFDSEGQLDELPYVEEEVALSPRYSGPAKVFHAAGQQDWARFQRRQSLMIDPMHPGQSRYSHSRKYEPTRSHAKSRSTPTTQGTSKAAARKPQAMDGLNIAVVGASGVGKSAFIQQVVGLSRPPLSDATTLSFAINNTTYPVTLFELNLEAFDFGPAQPFQWPKQINGHITPQVDGALILYDVTNIESTRDLHKTLNALTNSSLPAVLVACKCDRPPNCREVNAEVMANHERFKACAGSVASSSNNPEQARIGLSTILRAALHMRREAIEPPYRRRAASTANLEVTPFDANHHSSRPLSQQSSKHSRASSDMSVIRGFSSATHNPDQYRARSPRGAFPSSSEIFGADIEEHSPEPPSPIIATPTTTSTSCSSFHGKKATNISLNSVTSSDCFLDMDESDGEPSSSRRGSDDVPILQRDGDALYDMELDRSSAKGDHLSNTRNQAAGVTLDDLINRLLALRMAKAEHNFANVFLCMYRKFAAPGDLFARILTRLDHVRDDKTQHYLTKTATQLRIVDVVVRWVSLYPGDFARPATRRNLREFVRNLATEPIFAIAAQQIQTCLASSVVDDDDTGWEMSDDPTENDADRAAAGQSVSDMFSGIIALRLEDDDRMPLTHGLDLEIHGHSSLSATSGIQCHYNSVEDYERAASKLVPVEMFPMNKARFHQFMEISNEEVVSEMTRIDWIMFSSIRVRDLIRYVSLSAQQKAKAKSLKNVNRMIMHFNHIARWVANMILLRDKPKHRAQIFEKFIDIAHRLRGYNNYNGLAAVLAGLNSTSIHRLAQTKALLPADAQKQLAMLTLLMATQKSYFAYRLAWENSPLPRIPFIPLHLRDLVSAEEGNSTLVSSDKNTTLINWAKFDVLGEVLLPIMRSQGMEYSNLRRNESVRELLLECRMPTDEDEIYARSTELESTLANSSLPPDSLKKKFPWFAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1Z4</accession>
    <name>A0ABR3Z1Z4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003542</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000086">
        <property type="protein sequence ID" value="KAL1894651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040052">
        <property type="entry name" value="RBM17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13288:SF8">
        <property type="entry name" value="SPLICING FACTOR 45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13288">
        <property type="entry name" value="SPLICING FACTOR 45 SPF45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="2">
        <location>
            <begin position="335"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="185"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="503" mass="54026" checksum="7E06F5743660F977" modified="2025-10-08" version="1">MSSQSPAKPAGLSLYADLLEPEPGASNATDSNAAAKKKAADSALRFQPIRRTAPTKQKPKSVFSASVPAPNAPNSAIPAQSVAAATTAGSTPASTTQAPPVRSRLSDWVPSKADEWAYGTGEKRQRGGRKNKNKQRNHEQRETDWEDVYDPSRPTNVDEYLKSDERIGEIREWKDILYGHRKSYSRSGSPSSGSRSELSSDEGRDQRPGLGAKIAPPPGLNFAPPPEPQEIPMDISGDDVYARRLAMSQGQKPGPSVPTPTLVPASASVGVVASSAPVRYAHVQRDNDGNDPEESGDWDDDPRPALGLGHSSTANDDDNYNDANIGAPRANRPGQSGFAGRMMAKYGWTKGSGLGAESDGITSALSVAVEKRRKRPDAEGGGWADPGGSRNKILGGQRNNEDGGQFGKMSDVVVLSGMLDGMEDLAREIELGLGQEIGEECGEKYGRVERLYIDQASRRVFIKFTNQISALRAVSELDGRMFSGNTIKPAYYDSEKFEACIYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z248</accession>
    <name>A0ABR3Z248_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Interferon-induced GTP-binding protein Mx</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_003762</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000094">
        <property type="protein sequence ID" value="KAL1894281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF66">
        <property type="entry name" value="INTERFERON-INDUCED GTP-BINDING PROTEIN MX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="5">
        <location>
            <begin position="35"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="4">
        <location>
            <begin position="579"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="426"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="675"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="743"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="426"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="676"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="695"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="743"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="812"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="824"/>
            <end position="839"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1894281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="845" mass="95688" checksum="E3F72F322DC9F1E5" modified="2025-10-08" version="1">MTRIIDSTLNTHGLADDQRGLLELIDKLQFAQLDNVKLPQIVVVGDQSAGKSSVLEALTGTPFPRDSGACTRFATEIRMRRAKESTLKVTIIPDRSRPQSEQLRLLQYGGHVNENTSFESLMRDAGDLIAPKGIPGRFAARDILVVEKRGPDMPLLTLVDLPGLVRVANRDQSESDIRTIEALSDRYMKSSRTIILAVIGGNNDYVQAPILRKARQFDPSGSRSIGVLTKPDLTEGIGLEDKFIELVMNEDTENYFKLGWYVLLNPGPPLHGEAWPSPAERQKREDEFFSRGKWSTLPASMRGVGALRQKLSTQLQKHIGRHIPSLRKQIQDALSRCDHELKQLGEGKDTVEEMKLEMGELFSTSNNLVTPAINGNYKNPPGEKFFPRQAISKGTPPQRLRARVREESERFARRFRDSARKVKFSDTTGASGVSSTLNGLGSQSKKDFARNHVEPLLAQVRGTELPMDSNPRAPYILFQDYAQNWPTISTEFKDNIVVICNEFLSEIIDYVWPQRMHSPLREHYLEPMMADLIKQAEKELVRLTEDMELEIQPFDPEYEERLKKWRHQATQEGQTYTEAEEVLEKMLIYYDCTARIFIRNVITQIAERYLILGLLRLFNPVKILQMSNAVVEAIAAENKQTRDRRITLKNQKHAIEEAKTLCANLAMRSDLRSAYEDDYGEDSEDETVIRRRPTAATQNNGTSLREQETIVKSQHELRQLEAAKQAALQYQQQQILASEQAAALKAQQQGSPQRSSHSHSHRNSTHYYKENDGDPSVSSSRSKSRTDPPVSGDWEHYKRTSSGSEGPDVPSTAPPPPPPPRPPYHLEDQASAMPRREPRPYVARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z287</accession>
    <name>A0ABR3Z287_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_003694</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000092">
        <property type="protein sequence ID" value="KAL1894312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053037">
        <property type="entry name" value="Pericyclase_pydY-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38115">
        <property type="entry name" value="LIPOCALIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38115:SF1">
        <property type="entry name" value="LIPOCALIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1894312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="205" mass="23214" checksum="A3260E083C54E35F" modified="2025-10-08" version="1">MAAPKEKNIGDLNGVWVINSELSDSTDEIFKLQEMPYTTRTVIGYSTVTLTLTQSLGKPPAPAPEDAPDVTRVVIEQHLAPVRFMPSIKGTCENRCLDGLTRSHEDHIFGKVEGYSKFLERSEIKDVDLEKNWAPEDEERAGPENKAHILSFVRNLDEGKGWEATQIWGFQIVDGQRRYCRNIRVTKPGAQTLYARLVYDYKATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z317</accession>
    <name>A0ABR3Z317_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Serine/threonine protein kinase</fullName>
            <ecNumber evidence="7">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">IME2</name>
        <name evidence="7" type="ORF">Cpir12675_003422</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000080">
        <property type="protein sequence ID" value="KAL1895006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07830">
        <property type="entry name" value="STKc_MAK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="27"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="366"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="589"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="699"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="373"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="392"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="704"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="780" mass="85330" checksum="9F5DE18B75D1F723" modified="2025-10-08" version="1">MTTTAELTHRGLSNSHAPNTLPLEDRFEILKDIGDGSFGTVVLARIRTAGANIARRGSVVAIKTMKKTFDSFAPCLELREVVFLKTLPVHSHLVPALDIFLDPFTKKLHICMEYMEGNLYQLMKSRDHKCLDNATVKSILYQIMLGLEHIHAHNFFHRDIKPENILVSTSTSDMSSLRRYSSLVATPSSHPIYAVKIADFGLARETHSKLPYTTYVSTRWYRAPEVLLRAGEYSAPVDIWAVGAMAVEIATLKPLFPGGNEVDQVWRVCEIMGSPGNWYNKTGARVGGGEWKEGIRLANKLGFSFPKMAPHAMETILQAPQWPASLSHFVTWCLMWDPKTRPTSTQAIAHDYFIDAVDPLRPRSSASRILGRKQSDISHRGSKDVGSMLAGHTSNPALTSKPSWFRKSLIGRSESNPDHSAVSHSSPGKDAPRPSPVSVVVGGPAVSEVPAAAAKKAANAAKRATWANGSTAPINILPSIKPISPISDAVNAQANKDERNKKIARQLSVNSSTNNYIDKNSVTSPVSGQKESFFSHLRKRARRLSGRHMTPASPSYDDIEAQAGCSPWAVNNNRNSMIIDSTIAPKPENYDGASKLSHPAHAHPIPYHAAPPPPAHQNTSNLKRHHSLPKAQQPKSVDNLLGAARNTGSLGSRTTRRSKIVAPGGRQYDTPDEEDELLDEVLSSTQNVMQQMDKDYNAHASSKPLRQSASTMAISNPYPTPSPSANGNIALFADQTSLAPKPLDIKKPLDTQLKWPTPPYEESEWAASASASIWAASNRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3I1</accession>
    <name>A0ABR3Z3I1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Riboflavin synthase alpha chain</fullName>
            <ecNumber evidence="4">2.5.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RIB5</name>
        <name evidence="4" type="ORF">Cpir12675_003532</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.9" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000085">
        <property type="protein sequence ID" value="KAL1894791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004746">
        <property type="term" value="F:riboflavin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00402">
        <property type="entry name" value="Riboflavin_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001783">
        <property type="entry name" value="Lumazine-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026017">
        <property type="entry name" value="Lumazine-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006767">
        <property type="entry name" value="PRK09289.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00187">
        <property type="entry name" value="ribE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098:SF0">
        <property type="entry name" value="RIBOFLAVIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098">
        <property type="entry name" value="RIBOFLAVIN SYNTHASE ALPHA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00677">
        <property type="entry name" value="Lum_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000498">
        <property type="entry name" value="Riboflavin_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51177">
        <property type="entry name" value="LUMAZINE_BIND"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="105"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="105"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="209" mass="22821" checksum="40A43B019D06598F" modified="2025-10-08" version="1">MFTGIVETVGSIAKANHQDETGGTSYTIAVPSDSDLLSDCRLGDSIAVNGVCLTVTSFALMPSPEFVVGVAPETLRVTNLGTLVEGSYVNLERAVRADTRMGGHFVQGHVDCTAEIVDKRPDGNAITFRFRPAGKDLLRYIVYKGYITIDGTSLTVTTVNDEECYWEVMLIAYTQERVVVAKKNVGDLVNIEVDILAKYAERSMAPYRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3P8</accession>
    <name>A0ABR3Z3P8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_003341</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000077">
        <property type="protein sequence ID" value="KAL1895158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF8">
        <property type="entry name" value="BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="734"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="135"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="814"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="814"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="849"/>
            <end position="864"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="871" mass="95509" checksum="78C0C5C535D15C15" modified="2025-10-08" version="1">MPLPKSAPAGVSSSTHLTIPDSTSFDPALSPSPSPSTPSGRPPKWTVLSMWTLIMAYMNTHLSLFAVLKVVEAFARDPSDVPKEESAHKKISSTAGKELRWARANDVADALSRLKSLVLSPLFLSRVREAGHSLPLKAKNKDNKSHTTSAQEVNDDDNEDKRTTRDIQGGVSRNCKPLLNTQFECEFGLSQRSNTELSIMTTESVENGISQISESLPDQVHKDPLGRVFMKYLYILITHITFTLSANVHHRPKLESPLEADSRYRDSWAHDPDSPEDLDAPPPVPWDLLRPMDPNSLELSASKLQCQGAKTPGHKRNQCPCHLLPALQTSVWVQAIDSAQGLTPFASLVQSSDVGRFSGLIDCFGNTALHMLALGDAQHHMLLQAVISHQELVGHMNSMGQSFLHLLSPTWLNDAAALEVLLEPLAGDTRLFYACDHYGRTFIHLLAEYARQSAEMGRTLSRIMLRFNVELSPDAFGLHPKTGNKRTSLMPQVMDMFPKLDMAFNSESKPVASCSVNGIGRGVNGDGTDIDSSLKTLSDEDFFAHAHRRSEDYVATHTRLLSVVSKAFIDPKAQDERGRNALHCLGAAITSVQTMRSEQAEIAAGSMPRKRKHSRSNVSINTVPIAAGSPPQPAVWISPNSAAAAPPIVKPKSPVEEELELEDTSKERMKQRIETTRNLLSLGVDVNAYDHRGNTPLMAFVANSLESSADRSSPRTLIKLLVDGGASIHARNRKGETALHVAVRRGNKLAMRALVEAGANVHVRDGFGRSVLDVLDEKFYSAQREGRQVHVREIARFHVCRAILAGSAMGAKQNPTALEEWSSSTLGSAREAKSRRKLAGALKKSPKVALEDHSEDIGGDEDHVRQKRRIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3Z2</accession>
    <name>A0ABR3Z3Z2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">T-complex protein 1 subunit gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">CCT3</name>
        <name evidence="12" type="ORF">Cpir12675_003263</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000074">
        <property type="protein sequence ID" value="KAL1895356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03337">
        <property type="entry name" value="TCP1_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012719">
        <property type="entry name" value="Chap_CCT_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02344">
        <property type="entry name" value="chap_CCT_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1895356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="541" mass="59081" checksum="4877A0F5E43D86EC" modified="2025-10-08" version="1">MQAPVVVMNTGGPQQRQTGRKAQMSNITAAKIVSDIIRSCLGPKAMLKMLLDPMGGIVLTNDGHAILREIEVSHPAAKSMIELSRTQDEEVGDGTTTVIILAGEILAMALPELERNIHPVVIISAFKRALEDAIKIIDEISMPIDTSSDSAMIGLISSSIGTKFVSRWSDLMCKLALDAVRTVTWEVSNGKTEVDIKRYARIEKVPGGEIQDSRVLDGVMLNKDITHPKMRRRIENPRIILLDCPLEYKKGESQTQIEVSKEEDWNRILQIEEEQVKAMCDAIIALKPDLVITEKGVSDLAQHYLVKANVTALRRVRKTDNNRISRATGATIVNRVDDLQESDVGTQCGLFEIEKIGDEYFSFLTKCQNPKACTILLRGPSKDILNEIERNLHDAMGVARNVVFHPRLAPGGGATEMAVSVRLNQLAKSVEGVAQWPYKAVADAMEVIPRTLVQNAGSSPVRVLTDLRAKHAEGKHTWGIDGDNGTIADMKDYGVWEPEAIKLQSIKTAIESACLLLRVDDICSAKKAVQGGGGGGGGAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z418</accession>
    <name>A0ABR3Z418_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutathione hydrolase</fullName>
            <ecNumber evidence="1">2.3.2.2</ecNumber>
            <ecNumber evidence="1">3.4.19.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Gamma-glutamyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Gamma-glutamyltranspeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003416</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an N-terminal (5-L-glutamyl)-[peptide] + an alpha-amino acid = 5-L-glutamyl amino acid + an N-terminal L-alpha-aminoacyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:23904"/>
            <dbReference type="Rhea" id="RHEA-COMP:9780"/>
            <dbReference type="Rhea" id="RHEA-COMP:9795"/>
            <dbReference type="ChEBI" id="CHEBI:77644"/>
            <dbReference type="ChEBI" id="CHEBI:78597"/>
            <dbReference type="ChEBI" id="CHEBI:78599"/>
            <dbReference type="ChEBI" id="CHEBI:78608"/>
            <dbReference type="EC" id="2.3.2.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:59468"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="ChEBI" id="CHEBI:143103"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>glutathione + H2O = L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:28807"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:61694"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Sulfur metabolism; glutathione metabolism.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.2" evidence="1"/>
    <dbReference type="EC" id="3.4.19.13" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000080">
        <property type="protein sequence ID" value="KAL1895001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043138">
        <property type="entry name" value="GGT_lsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000101">
        <property type="entry name" value="GGT_peptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043137">
        <property type="entry name" value="GGT_ssub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00066">
        <property type="entry name" value="g_glut_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11686">
        <property type="entry name" value="GAMMA GLUTAMYL TRANSPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11686:SF62">
        <property type="entry name" value="GLUTATHIONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01019">
        <property type="entry name" value="G_glu_transpept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01210">
        <property type="entry name" value="GGTRANSPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046974044" description="Glutathione hydrolase" evidence="2">
        <location>
            <begin position="19"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU368068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="566" mass="61264" checksum="6E3CBEC45D901BEA" modified="2025-10-08" version="1">MKLTNSLLLAVALASVAAFQPQIVVDSKANRGKTGAVASESIECSEIGRSILKRGGTAVDSLIGTVLCVGVVGMYHSGIGGGGFLLVRDSRGKYEAIDFRETAPAAASEDMYHDNIVDSITGGLSVGVPGEIRGLQYAHKKYGVLPWKDLVMPAVEVARNGFRVTSDTIKYIDKALAEAPYNFLAENPVWAEDFAPNGTLLGRGDIMTRKRYADTLEKIATQGPDAFYTGEIAESLVNTVHSSNGILTMQDLEDYKIQTREPLSVQYRNYTLHSIGAPASGAICLGNLKVMEQYDLLDWKNTNLSVHRLDEAMRFAYGARMKLGDPAFVKGVSSLEASLLQDSTAEDIRNKIDDDYTQPVERYIPQGIFVTEGQGTSHIVTADKSGMATSLTTTINLLFGAQLMDPVTGIILNNEMNDFSIPGHHNEFGFAPSPSNFIRPGKRPLSSVSPVIIDTPSGSLYLTIGAAGGSRIISATTQTIWHVIEHGMILDEALARPRQHDQLIPNQVTFEYSFDNATVDAMQNRGHHVTWVMEGLSAVQAIRVGEDGVFEPASEPRQKNSAGVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4D7</accession>
    <name>A0ABR3Z4D7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein uL3m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_003549</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000086">
        <property type="protein sequence ID" value="KAL1894658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_uL3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019927">
        <property type="entry name" value="Ribosomal_uL3_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_uL3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03625">
        <property type="entry name" value="L3_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229:SF8">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL3M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="234"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1894658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="348" mass="37432" checksum="4D4861128E07DF61" modified="2025-10-08" version="1">MAPRLPCRVGSCLTLPLRLLEHSIPDSFVTSPVTRRLFSQTARHSVKYGWSTHPPRSNPHEFRPADSGLSPLTTSPDAALARKAYTTPVRTGVLAIKKGMSAMFVGKVRMPCTILQLDQVEVVATKNHDTHGYWAVQVGMGTRKAANVPAPQLGYYEAKGLAPKKHLAEFRVRNNDGLLPVGVQLQPSWFKLGQHVDVRATSKGKGFAGGMKRHGFDGQPASHGNSKTHRAIGSVGPSQGGGSRVHPGKKMPGRMGGESTTTQNLEVLQVDDKMGIVVVKGAVGGPKGSLVKIADAIKKKVPPELHRSKALSNLLEAHPDAEAKLEAARKLHLQLKTARQEMALPESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z562</accession>
    <name>A0ABR3Z562_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">DNA repair protein rad50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">RAD50</name>
        <name evidence="17" type="ORF">Cpir12675_003104</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SMC family. RAD50 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000068">
        <property type="protein sequence ID" value="KAL1895771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004584">
        <property type="entry name" value="Rad50_eukaryotes"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00606">
        <property type="entry name" value="rad50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18867:SF12">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18867">
        <property type="entry name" value="RAD50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13558">
        <property type="entry name" value="SbcC_Walker_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10 14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Rad50/SbcC-type AAA" evidence="16">
        <location>
            <begin position="6"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="337"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="812"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="232"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="405"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="719"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="846"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="1031"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="812"/>
            <end position="829"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1895771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1310" mass="149704" checksum="187CF3E8CDC3696E" modified="2025-10-08" version="1">MSKIDKLSIQGIRSFSPASRETIQFNTPLTLIVGYNGSGKTTIIECLKYATTGELPPNSKGGAFIHDPDLAQSKEILAQVKLSFKSANGAKYVVNRNLQLTVKKATRSMKTLEGSLLVLNNGERSVVSTRVAQLDEAIPSYLGVSPAVLDSVIFCHQDESLWPLSEPSALKKRFDEIFEAQKYTKAIDNLKALRKKKGEDLRILKQREENDKVNKERGEKAEKESRAIQALIEEDRAKCKRITAEMQETKNRIRELREQSSSFLTLIYDLRDKRNQLKFREATTIELKDTLDELPDDDATLEADLANYEERMRRFEQEANANRAQYSKLQADLAAARRDHSAKLAEQGKHQSDKEKYERQLQARSQLIQIAAQEHGFVGYDDGHISESQVLSFTERIQRLLADKKKDLERVKNHVSQEVEKARSAIGDLERKQSNLDHDKHTAKQRIDNIDRQSLNLNNRARNLDYEESSLVMLEGQSHDAQERLEKARAHLAETDYDARIKHEKNVQSDLSFESMKLNRELVECSRLAQDRAQLTFHKDQMAKRKLTLDSLKTTWKDKLDNFLQAEWTPENLDSLYQTAVAKQEARVRDAKAKRDQVLGNQTKLDVRLKAARSSLASTVEEAGKCEKRVASYLKSINEESLGASDFDGELSHYEEKVEDCKAEIGLWDALAKYYTQCHKYLNTKNSCKLCERPFDTNQSAFRARMEKKIREKLNPKEKEESEGELAETVRILEELKSLRTDYETFKRLQNETPSLKSQASTLEAEYEQLETAVMDVETSLVGDDEHLSSIKTLGKTATTFAQTLKEIAESESSINRIESQQSASSDASKTAEEINTLLSECDAKMRAAKSKEDDLLSEKQRYRDQLNTCEMELKDIQGKLSHAKMQLEMKLDLQKQIKSLKDDHTQQREAISKADQELEVVGAQLLEARTFLEEILRDGKSKEKAITDERDVVMASINELKPIENDIQSYLDARGPANLQMNQKLIASLEQHISTLDEEIAQLAAKGNALTTEIDNGDRQKKNISDNLHYRKNLRLLEVLKEEIRDLEERDATEDHRQLEDEANALESHNSKLLAERGSVMGMMKSRDDQLRKLIEVWDMEYKDAAHKYREAHIKVETTKAAIEDMGRYSDALDKAIMQYHAMKMRQVNETAIDLWKSTYKGDDIDYIMIRSDAESATGRRNYNYRVVMSKQGTEMDMRGRCSAGQKVLASIIIRLALAESFGVNCGIIALDEPTTNLDTDNIKALAHSLHDLIQQRQAQSNFQLIIITHDEEFLRGMRCGDFCDVFYRVKRDDRSNSVIMRESITNVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z563</accession>
    <name>A0ABR3Z563_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7721 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003098</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000068">
        <property type="protein sequence ID" value="KAL1895765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056138">
        <property type="entry name" value="DUF7721"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39477:SF1">
        <property type="entry name" value="BETA-FLANKING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39477">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24845">
        <property type="entry name" value="DUF7721"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7721" evidence="2">
        <location>
            <begin position="63"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="228" mass="23874" checksum="21605E26725AD0BF" modified="2025-10-08" version="1">MDFLKTVASEYGKSQQGSGSNDAQHQQTNQSNVNSSNMPGNLSGLHGMLLNNNIFDVLDSDADKKKTAEAAAQASGSHDNSDMFHSVLNKLNQNKHSVAQEKDNVDEDFAVKMFKKFVEKKDTSADEKASSNNLGAAAAMQAIKMFNSGSGSSSSGSGGQAALLGLAMSEGSKLFDNAQSEGKVAKGTTKESVIEQAVQFALKFFLKSQTSGSSGGNSGLMGLAAKFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6E0</accession>
    <name>A0ABR3Z6E0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_002903</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ARS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000062">
        <property type="protein sequence ID" value="KAL1896196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025239">
        <property type="entry name" value="DUF4187"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039727">
        <property type="entry name" value="SE/Ars2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007042">
        <property type="entry name" value="SERRATE/Ars2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021933">
        <property type="entry name" value="SERRATE/Ars2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13165">
        <property type="entry name" value="ARSENITE-RESISTANCE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13165:SF0">
        <property type="entry name" value="SERRATE RNA EFFECTOR MOLECULE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04959">
        <property type="entry name" value="ARS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13821">
        <property type="entry name" value="DUF4187"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12066">
        <property type="entry name" value="SERRATE_Ars2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01173">
        <property type="entry name" value="DUF4187"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="682"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="152"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="594"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="729"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="66"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="734"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="800"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="821"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="838"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="868"/>
            <end position="878"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1896196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="878" mass="99744" checksum="4673E07919AB0C0A" modified="2025-10-08" version="1">MDSYYRDSGRSPHDRMRSRDPIRSKEERGSPGYYRDRMRSPIHERGHRRRSRSPGSGGSTGASGLDRYEPRGGSRRDEYAPRDRSDRVDDRSSRRMVSPPANIDRYVPGQEPAGSAGITVNPVPDPSKLPYQVGFSYYGEWWRFNEKIKEEKERIRTGRRREPDRNKSPRDIAEEREREKTRIQMAYDSYKEELQAKMARHFVTEHKKEQWFKERYDPPTRDEFRAALGEFRRGAYAQWEQDMDAGVFDRFSLEGINKGEQGNAVAQEKEEGEATSSNEVLGVSDLVPVLGADIRDENLYQPTLLIKTIAPHVSRSNLESFCKEHLGDGEGGFKWLSLSDPNPSKRYHRIGWVMLHPAPEVLTTIDRADPRDDDEDMDGIKTSAPVQSTAEKALEAINDKTVKDEARGDFVCHVGVHNPPSNPRKKALWDLFSSPDRIRKDLSLVHRLANKFEEDFGVEFSGIARVQEKVQDLQNAGLLRPMISGRRARKERVVDLDVEDDGELHDDDGEIDEEGMYDEDNESEDFIAQKKELDLLIEYLRRVFNFCFFCVFESDSVHELARKCPGGHLRRPASTLTQASREVAIATVTGEPFPVKKKAEPMEEGEAEQSESDKKFRSASSKTEQQLLRAYNWVKTFEDKIMQILEPDSVDMKKLGGRPLEEAMDEEMAKFVKQEDEHKWRCKIPDCNKLFKEEHFWKKHVEKRHTEWYESLQHEFTLINSYAIDPSHIAPSRTDANSNGHFPPSNGQSTAGTPRGFSLHSMSIGGPGSHPASFAMGQGMIPMGMPAGWDGRDGSTGPVRRNGNNRNNYRAGPYDRRQNGGRWDSNNRNNKNSSGSRWGDGGSGGSTTGPREAVQGRSLKSYEDLDQVGGGAGSELNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6J5</accession>
    <name>A0ABR3Z6J5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_002849</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000060">
        <property type="protein sequence ID" value="KAL1896256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046982">
        <property type="entry name" value="BIN3/RVS161-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174:SF2">
        <property type="entry name" value="SH3 DOMAIN SIGNALLING PROTEIN (AFU_ORTHOLOGUE AFUA_5G07670)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="400"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="282"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="352"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="354"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="372"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1896256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="459" mass="50797" checksum="BB61A1BDC029D497" modified="2025-10-08" version="1">MQATRRQLGKLINRDLVESSHASVVIREYEDIDRLLARLVDDSRSLRDSWVHLGISSLNTSTELLAMYRPYIDDYPSPEPTNRPPERIPELQMSQASALEVVYHELKADIVNEVTMFDAGVINPASKARELIAGFRKTIKKREAKRVDFEKSQEKVTKIQKKTSALTPKEEVLLTRAQQDLDHAKEELSIMDEYLETTLSKVVGATMQLVIPLVSSLASTQIRLLGMTYTALHNYCQENDFPSPAPDMDEILADWTTAFKPVQRQFEAISFISTGRGRLAALDLGDDTPPRPTLGPRASTTALARKDTTPPPPSGLREGLHTLAPTDFTAAARLGSAAIRTPVTRAVSVEHFGHQSTSQTHSTQAHRPGMPQPSSAPVSSALTTKKKPPPPPPKKPTLKKSEEYVIAQFDFAGQGAGDLPFRQGDRIKIIKKTNTDQDWWEGEIGNARGSFPANYCKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6U4</accession>
    <name>A0ABR3Z6U4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_002970</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000064">
        <property type="protein sequence ID" value="KAL1895994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03233">
        <property type="entry name" value="ABCG_PDR_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029481">
        <property type="entry name" value="ABC_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034001">
        <property type="entry name" value="ABCG_PDR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010929">
        <property type="entry name" value="PDR_CDR_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14510">
        <property type="entry name" value="ABC_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06422">
        <property type="entry name" value="PDR_CDR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="517"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="541"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="588"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="623"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="653"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="760"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1182"/>
            <end position="1202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1214"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1253"/>
            <end position="1283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1295"/>
            <end position="1319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1325"/>
            <end position="1343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1355"/>
            <end position="1374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1449"/>
            <end position="1468"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="133"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="844"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="811"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1895994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1489" mass="166186" checksum="4339F5FE113B7201" modified="2025-10-08" version="1">MEPYEEEAKFEPVNSGHRRDLSGETQNNLRKTPSRYADDEQVAAADYDESTRRELQRIATALSRRQTGGTASEADIVVPDFSSDPELDPASPSFNLSKWMQSFVQTLKNENIQRTSSGVSYSNLSVTGTGDAIQMQDTVASFLAGPVMAVNRLLRGTPTPPKRILRKFDGLLNPGELLVVLGRPGSGCSTLLKTICGEMHGLQQGAESVISFNGVPQARMVKEFKGEAIYNQEVDKHFPHLTVGQTLEFAAAVRTPAVRPHGLSRDEFCKYAAKVVMAACGLSHTYNTKVGNDFIRGVSGGERKRVSIAEMMLAGSPVSAWDNSTRGLDSATALKFVQSLRFAADFSGGTHLVAIYQASQAIYDLFDKAVVLYEGRQIYFGPANAAKDYFERMGWYCPPRQTVGDFLTSVTNPGERQTRQGFENRVPRTADDFERYWHESPEYKNLMGEIDVYTQANPIDADGAGFKDMKEGKALRQMKHVRPGSPYIISMGMQIKLNTKRAYQRMWNDSTSTITDMAIQLLMGLIVGSLFYDTPAATAGFFARGSALFQAILLAALSAISEITKLYDQRPIVEKHHSYAFYHPSTEAMAGIVADIPIKFLASVIFNIILYFMTNLHRSAGQFFMFFLVTFLMKFVMSAIFRTMAAVTKTVSQAMALAGILVLILVVYTGFVIPQPAMKDWFAWLRWINPIYYGFEILIANEFHGHEYTCSSIIPSYSPPQGDSWICSIVGSRPGRRTVNGDDFIWTNYRYKWDHTWRNVGIICAFMVFFMAIYFIASEVNSSTTSSAEVLIFPHGKVPSHMANGHNRAAQNEELAHSGSNSEKSGKGGRAGDTTAIEPQRDIFTWRDVVYDIEIKGEPRRLLDHVAGWVKPGTLTALMGVSGAGKTTLLDVLAQRTTMGVITGDMLVNGRPLDPSFQRQTGYVQQQDLHLDTATVRESLRFSADLRQPSSVSKKEKYDYVEEVIGMLNMGDFADAVVGVPGQGLNVEQRKLLTIGVELAAKPKLLLFLDEPTSGLDSQSSWAICAFLRKLADANQAVLCTVHQPSAILFQQFDRLLFLAKGGRTVYFGDIGENSRTMLDYFESHGARKCDDDENPAEFMLEIVNNGENNQGVDWHDVWKGSNESYEVSAEIDRIHAEKMSEPVAESDHSAVAHSEFAMPFRNQLVCCTTRVFQQYWRMPTYIFAKFFLASAAGLLIGFSFWKTDTSMAGMQNVMFSVFMMTVIFTTIVQQIQPQFVTQRSLYEVRERPSKAYSWKVFIISNVIVEIPFQIFTGILGWCTFYYPVVGIQSSIRQVLVLLFLIQLMVYASSFAQMTIAAIPNAETASGLVTLLTIMMLSFCGVLQTPDAMPGFWIFMYRVSPLTYWIGGIVSTMLHGRKVVCSEAEVSKFNPPSGMTCGTYLADYLVDAIGVLQNPNDTSDCRYCAYTLADQYLAPSKIKWSEKWRNYGIMWAFVLFNIFIAVVTYWMFRVRKSGGKSPKTKKKPSAKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z748</accession>
    <name>A0ABR3Z748_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002759</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000057">
        <property type="protein sequence ID" value="KAL1896470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="759"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="761"/>
            <end position="800"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1021" mass="114121" checksum="8EFDC90ECFD211BD" modified="2025-10-08" version="1">MSADRVTELEILLAETRHRADSEAQARKDVEAFAAHIQDELSDIQDKYKDMKRKVEEHFPQDHKNVFSSLQAQLGDTGVFPSQMKVQVNEEEMEAAIPTDFSRANWVYNCARTYTFLDRAVEKPSSNILAQYFAAIGDKKGFFFDNGTSKINTAAGTSANAPRRRRKSESVRLVKMDSAETVSRTALPTKPQPDCLVLVRDGWADHTQPSPEPYCLVIGEHKPCHSLRASDLRNSPVLPEDCLIQMASEREVEVVEKEKEKNGKANPLQPIRTLITPSGPPIPSSRISKKLSFFAFALAQAYHYMMMSGLEFGYIATGETMTFLRIPLAEPTTLLYHTSFFPATDPNYLPRSDGVLQYPSGATTSSALRHVAQPDDGSLAELAVSQLCSLCIMAASSSVRPLAWVNEALNHLAKFPKLPTSHNLMSVSPLDLRQCDNNSGSVNENETHSSVQKLYQHSHPVDIHSSNHRALSPLRQTPQPLNGNTHRQHQRALASASIKAVKENKMLPYCTQACLLGLTRRLPLDPGCPNYPLHRDAQPAATSSASLPREQQMHAITKADIRALIREQISIHPENNCTLLYNEGLYGAIGCLFKLSLNGYGYTFVAKGVESDNACRLRRETQIYKRLYRQQGVLIPVHLGLIKLLSPYPFMAKFTTLSHLMLMSYVGKALHYGPSLDELGQELGRDLNCEISDTYQQLLYWGLDDRDEDVCNATWCEETQSVMKIDFDHCILDVDIYAARVKALEDVTGDDYFTVKRNVMAEEDEEDDDDDESGSSKDDDNDEYCEDDDGNSYSDEDDNGDNYAHESDDGDNYADKCHADNDCAGGNYIVSDNDVYRCNGESRLVDDDDEGAYEEVGYEVIKHGGGSSTKKRSIADDDEIRDGYAFKDLGYGLCTVTSQHSSEGRELLDKFEVNKADKAITVENFNVVETNDSNQLSTSAIMASICRTYDLEPDNLNEVVMGVPKDYCLQRALDAYRSIHSDMKENEKIVTTLTLGGTYPDLDRDVWFDLCQCMPYKVVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z776</accession>
    <name>A0ABR3Z776_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000063">
        <property type="protein sequence ID" value="KAL1896022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="486"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="491"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="534"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="565"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="643" mass="73274" checksum="DEACD6A38AB0F7B3" modified="2025-10-08" version="1">MALPSYLREFPVAIIHYRWSGKTTRISALSVPMFWPHPMSDISFAYARLVKYLKPPGGKYRRRDFYVYGTKLGAGLAMSLALISCRPHVPVGIRGVAAWDGIYDWTRFLPDHWDNRFSDHDDVNNSNRKIKWKYMTAVARLKKRMPALFSDPGNLFDAYASPVLFFSTSGLIVPETFHKTVYQQYEDKYMPLPASHEEEAMERLRREHDELYGFLDVSYEEERHALHPDPAHQSHMLRRLTAGSQPVDPVNLNFPPQESLLEIPETLMLYTSPPEELDLEPIEVSSLDHTGRLTPCDVDPLEVVFGPKPAPKKTPPRYRAPIVMPNTFKSHAIILGNFMVRSINEFEVKPREKWREPPEDFEEYLERAQYRVIAADAGPAESNDLVIPEQGQGLLLNWLRPRLLGMEMQNNTELLERSGLEKVGPHAEEWEDEIANLIDGGFSEQPDFSEVKGQLEKVNDQVQDYLDNSDDRIELPAETIDEIQEVVSSEGLEEDFFSEEGSEGSERSEEIHENLSETRAKQEGSPIGSAIADEQAHVGQDHRPVETQASLDLGKKDATRVQAEQALSSDAQASLDTDMSLDDNSQDYNVPLEVEFDILQSLYEQERQEGDLVSDDTEVPINALVSEFERLYVDKEQQHQSVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7B2</accession>
    <name>A0ABR3Z7B2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pentatricopeptide repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000065">
        <property type="protein sequence ID" value="KAL1895980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050667">
        <property type="entry name" value="PPR-containing_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47939">
        <property type="entry name" value="MEMBRANE-ASSOCIATED SALT-INDUCIBLE PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47939:SF1">
        <property type="entry name" value="OS04G0684500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="530"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1191"/>
            <end position="1213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1213" mass="139393" checksum="7A3AC86B5D24E51B" modified="2025-10-08" version="1">MRADTRTFGCLLNSALTPTSCRSSTQIQIRPRPTVTYKKLKPMFWQHGGSAIELSSAWLSLAREKLKDVSLVSPPLASFLYPKDMADKAVLSQSLRTGLASVSIRTKSCSAPPSGTRKITVSARNTIPAPMMPLQRALGMSSLLAPDYLRYSKMRDVDTEPGEYYDAEIIQPLYVPAGPGQQPHYFQPQMSTSTKINEIIRNEDYQYSDLLWKLYQQLPPHEVPAIRLPMLLFLAQCSSAAELDRMQHLISTTPNIEFTNELTTVAVRLYIRLRDISKAFQYFYYGLSKTSLPQPLEDLLIYSFWLRDWQLLSNVWQAWINVRDDTPRLLEVAKIPNFHHHLLRFLKYTGFYDRHELPEDFSLIPDVPAQEPKDPSAGYIFRYQFHQRLANSRFRDLVQQLSKNVLAGDCPLWEAEPFLSLVALSEQYEAYIMKAAESKNHVCFDRVFKLYRNAKSYSPSQDFLQAVFLVAKQTKNDQMAIMAYEDWVRFHSYLSQGFMFKLMNYFAYRGDPKAVHTIWKRHRRDPIKAMKPKDSSMPLDKTRPKRAVPLHPVGNTENDAINDVQEPFDLRMTYRRYRLVAFAMQGSVKRARAQLDEIVRMEGGADLMLWNSLLVGFRRSKDYRGAVKLFMELTAVAQPDNKVFANMMSTAATQGDLQYALELFGQAKELKMENTVDIVEKVVFAFCCARQFTQGKAVLEWALESGLASTRMFNHLMRGQAAENKLLGVEAMVELMEKHSFSWDSYTFVAYMHGFVNTRMPEAGWKVYNMALKSRRLIPEAEHFAVLMYGWNISGQPWRTFEMDELMRKLDVPHSLDTVRLMVVAKRQSDEMYAKNPQMTQVPCEGGDPESLVNYYRRQLELNKTNMSNPREWHIHSVVHSQMVARSLATLTTIHHWDLAEELLEMYQGDTNFIKLPNSVLSPAMWIYYNKRDYAKVKSIWNKMFSSAVDSGRASASMVQSQVAEAGSEAAAPEPVADQLPHRTSDNSAVLSGVRWVLDGPFTTMRFVLTQEGDARGLLALANRLVANGFCLSRRNWNHVVQVLAQRGLHIDAFDICEKRLIQAWAGWATRRRRMGGGRALKPETRWLGRHKNTVFATSYTLIILLNEHQKLKEMEPWSSDAAATLEHLRENCKNVLDALNTWKYCGSEIEKDLFGENEMVRELKAHQERDLRYEREEFERLVRGEPLQPLNLRNEEDKDGPIGGVIVGTDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8E7</accession>
    <name>A0ABR3Z8E7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Spo12-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000056">
        <property type="protein sequence ID" value="KAL1896630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007727">
        <property type="entry name" value="Spo12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05032">
        <property type="entry name" value="Spo12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="104" mass="11344" checksum="5F51E607D4D7EBB6" modified="2025-10-08" version="1">MSAILSDQPLVDATVASAGATAKSDIKSMDYHRQMLQNKMKSEESQKFVSPSDNVMSPCTQKLNALRTKQASRMKPRSLFATATSARKLVEGDDMFAPKKSTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8F3</accession>
    <name>A0ABR3Z8F3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003082</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000067">
        <property type="protein sequence ID" value="KAL1895804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038609">
        <property type="entry name" value="HDA1_su2/3_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="114"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="351"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="438"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="977"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1292"/>
            <end position="1370"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1106"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="360"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="443"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="977"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1329"/>
            <end position="1338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1350"/>
            <end position="1362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1895804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1370" mass="151802" checksum="AEC782EBA0F0E4D9" modified="2025-10-08" version="1">MPPLESSAHPASDSFSAPKSSQGSYFTSPPKPGSPLLPQSPSVSPFQSQSQSQSQSESQEEWWEIRCILGERIRNGRVEYKVDWAPHSVTGQTYDPDWIPGSQVTHAARQEWILNKHQRPDRARNQNKHRRQGQGRNQGRNQDQRPSSSHSEDSSSTSRRVAQSITASGELASAHLSRLSKEIPDSLTELNNTPSRPPSPVVQSAIFISSGSPQAPQFVGDAQAPIHLSSSTSGIHPAQNPSPVAATTTVATPSYQANLGILSITALEASNSSRYRRFTESELCPSPSPQVVSCRQQRQLQVEIPDSQNSSVFSTISPFRLSQPVDLTRLQPISSKAVETESQPCIQRCDSHSAREPQLAPTSNQSPSCVSQEYRTLNSQPANSTTPLELLLEHPQKSPSQENFTFLSQVPPQFPSEGEDLTSLLATFRSSTKSLGLDHITETPINPSSRSRPSGEISINPKSTPAIDLMKQPLPRTAHSLTSPEHGHKRTLSSPGSQPLVKRTRVIKGKATSIMDLDDSIPLSSMDELLNMQTPYDPTRPIIVATDDMESDIPLPEDAQKGENSMEMTFSLLQGSNNLLPSEISPSIVSEAPSHPMVSACDAPMISGAVNPSALEFGSAVNVNPDLMLPQQNPSLLTIAPSDISRSVDMPFEDHLRESPHLNTSPVQHPIKEDTVESLQSLDGDIIYDGEREFLVTLPFASSQRPLYIDVIEKFKAYNKSFANIFFDEEYQEPRASLVHQIDEEFVTLLDLCDYPHELASKSLSELSEKEVQHYAVESNAKFNFLWEFLHELEETENKILIVVRSEKLLRLLKAVISAEKIPVSTSTLDETDYSRSTSSLTVVLALHNSEIIDPISSFNAVIGFDYMFRFSTAARQINAFPVSKQPFVLTLMMLHSIEHLDISMVKAQDAMEHKNAVVYGLVQGRDLIRNPRLTDYEKPHEIAFHFAEQVKDPNPHFAWDSQPFPKEILDGIYMSPQSSQANDSETGLDSQLAAGRKRKHINDPMKSSKRLKTSESAPPPSNLLVDADRHAAISPFVKIIGLHVLDVANAWNSREASIPERLLAAMCQKVTEDQLTISKEREIASDLRKVVQSMSKHITEYSTTLEREAKRLRESLEERAKFEIERNTLANENESLKAEVQNLKDQIQASQTEEKRRSEAATFTASIASATSLSTSNNSLSEATERIQEAEAKATSFEKRYASQSTEMEYFRQAYQDASNAASTLRKENTSLASQLQESQRSASDNILRIHDLNTKAQVEQLTRMINEAHAIQREREVDLERLRDELRVYKNGRRETRQSSAPRSPRVGMMSPRTTAAGFRTGGGSCSGPAPSSSRGTSPATLDVAGASNMQYFNTQQSGNGRWGHLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8Q3</accession>
    <name>A0ABR3Z8Q3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tryptophan--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Tryptophanyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">MSW1</name>
        <name evidence="14" type="ORF">Cpir12675_002797</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000058">
        <property type="protein sequence ID" value="KAL1896460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="entry name" value="Ribosomal protein S10 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.240.10">
        <property type="entry name" value="Tyrosyl-Transfer RNA Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_uS10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_uS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_uS10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_uS10_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050203">
        <property type="entry name" value="Trp-tRNA_synthetase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43766">
        <property type="entry name" value="TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43766:SF1">
        <property type="entry name" value="TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="Ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 12 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS10" evidence="13">
        <location>
            <begin position="120"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1896460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="538" mass="60762" checksum="2E69339B1550091C" modified="2025-10-08" version="1">MKGSTLMPRAIGPLWLSQMPTINGRRFLSRSAICSAEPVAPKPPFPTPDKLDAASETFDLSSIKKSIKYNKVNNSATKSSENTTSINEAEEKLRRLPMSVQAIYMKPLKRAAKYGIPSCDLQLRSYSLRPLEFFADFALRAAYYLNLPAYGPVPLPQITERWTVPRSHFIFKKSQENFERVTKRRLIQIRDGDPQAVQIWLAFLRKHAFYGVGTKANVWEFSELGVGKTMDVEVPESEEMNTAWGHFAQDRPYKFKDLEQLEKLVEQPKFRRPYRDAVTEVPAHSELMWILSCTSSVGYLSRMTQWKSKLSMSSTTNIQDEKARASLKLGLFSYPVLQAADILVYRATHVPVGDDQRQHLEFTRECVTNFNSVYKKKILIAPQTIIPLERRIMSLQSPSQKMSKSHADPKSRILITDSPEVIHKKIMSSLTDSQADITYDPQGRPGVSNLIDILCAFDPSERSPVELVEDLSGGTLKDLKMQVSEAVISALSGIGPQYTKILSEDNGKYIDFVEQQSAKKARQRAAETMELVRSAVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9S4</accession>
    <name>A0ABR3Z9S4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002532</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000050">
        <property type="protein sequence ID" value="KAL1897007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="301" mass="33780" checksum="5DFEA30A7CB082A1" modified="2025-10-08" version="1">MEIDRRDIWLDYPKARLSELCDKVSAVLPAFETFRPYIRAALAFTRPPNKTVNDGFLGLDRLLEILPLRKEEREAREMYCKIARAAAVEGSLRLTGRLEKAASQHRNLKSSQPIVLKQTASKRLALRYLRDDFYAKMQAIEEESKKNAAKEPHIGGPARSNHFINRIALSMVVEDPLTAIDNAATATAAAAKPKSVLSRGPCRVAGAPKSVQFGPRAFRTIPTREEEGNTEITYSVACPGYDFPEYLEEIFEFEQIQVDRPYRQQPAANRSGDNQSQEPQAESVQLNSSENQVNHATMSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA83</accession>
    <name>A0ABR3ZA83_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peroxisome chaperone and import receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PEX19</name>
        <name evidence="2" type="ORF">Cpir12675_002360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000045">
        <property type="protein sequence ID" value="KAL1897504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.900">
        <property type="entry name" value="Pex19, mPTS binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006708">
        <property type="entry name" value="Pex19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038322">
        <property type="entry name" value="Pex19_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12774">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12774:SF2">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04614">
        <property type="entry name" value="Pex19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="333" mass="35820" checksum="0DB67A53C722519F" modified="2025-10-08" version="1">MSAHPPPNPTFEDDDDIPDPDEDDLDDLDDMLDEFSAPKLSNAPGSIPSILSVVPPKSTANAGTLTPPKPEGSQFSPDDDISEEEFAKQLQESMANLLGGMGADSEEMQTQFEDIFKQISTEASATAAAATDTASPATAPAPKIPSRPSTARNDNAKDFQETIRKTIERMQTSGDQATAAAAANSSDDFVTEMLKQMGGGSGGAGIPGLDGGGEEDFSKMLMGMMEQLTNKDILYEPMKELNDRFPAWMAENQDKISAEDTQRYQTQQKLVKEIVAKFDDPKFSDENAADRQYIVERMQKMQDAGSPPPDLVGDMPSAQDALGAPDDEACNPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAP5</accession>
    <name>A0ABR3ZAP5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002229</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000041">
        <property type="protein sequence ID" value="KAL1897730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052061">
        <property type="entry name" value="PTE-AB_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260:SF3">
        <property type="entry name" value="THIOESTERASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_7G03960)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260">
        <property type="entry name" value="UPF0644 PROTEIN PB2B4.06"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1897730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="218" mass="23856" checksum="44721A3D1685EE54" modified="2025-10-08" version="1">MDQKVQDAIAHFSKTPWCAALISRPGATHFVPHEPRAGSVAVNLTQDRLFRKTLRTSSTVPYQLGFFQDPFGPYPETSKPASSSGLTMLNPIVTVLHDLQPGVNGFNGTTHGGFISCIIDEAMGSLIYTNYDELMGAKMKHKPPDNVPDLSDARVFTAGISVQLKKPILTPNIVAVVAELDRIETRKLLFKITVKNNEVVFAEAQGLWIVVPNAKSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAZ3</accession>
    <name>A0ABR3ZAZ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_002243</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000041">
        <property type="protein sequence ID" value="KAL1897744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="209"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="30"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="138"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="280"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="358"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="840"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="253"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="36"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="67"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="89"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="138"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="153"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="849"/>
            <end position="863"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="974" mass="107153" checksum="9D32F016E9283C5D" modified="2025-10-08" version="1">MEHLETQVSDLRYLAQAPTRALGVAIGGGLSMGIASPSPSSDPSRDQQQQQQQQQQQQQQQQQQPQHHSHLLSHSHGHMHGHPVQTQHHSPHPHPHPHQQHQRQLHGLSPTNSNPPPGTALTYQPTTQVIRPDAIAASSTTSHDVTGLSATPASSLQPSSISASGAPMTYSQSNDSAPGAKRKIEDAIDDQATPQKQQRSKRNRYISIACNECKRRKIKCNGETPCHRCGNLNLACLYAPNCCANNFKDSDEFKSMSSHLNQLQDQLDSLSQTVDSLKSDTAKLSSTGPAQAGVLSHAQSSALPPPTTASAISLPPLPPSALPSTIVSSPAQSSASLQRIDPALTIISGGSSLKALGLRGPSAYVDHNPPPPPSHHSGTENTYSQSGRGPYRSIIDNGSSGVPEPYGGHVSVHAYRHQSSSSVEDPLWDLSIDEITRICRLYDEECGVLSPMLVVNNVIVHARSLFSVMENTAKDRGAISLNDDKTLLLKIVVCCGMAVEDRGYSERAAALYDSMEAKLNKKLMADSVDVADITILALLAGYRYLINDDVLAWRIMGQVARLCIEIGLNTRHGIISIPNEEERKTAVLAFWAVFILDRRWSLCAGLPYVLTEDVVEVSLPIPEDQKSMVAMINYSRLASRVWRFVTNINAALIYDLRMEEVYSYDREIRQWYDSVPDEVKVRNWDTDKHMMSTPSYNLQRLRVWTYLRFNQLRIWLYMHVLKSPASIMHSLSHANAVVDLSKDTVRYLTHLNNTTPVYRRVQVYYQNFLSSVIAVLFLACTHAPGHFLSSSRDDFYHALDLSRDIHQKSWVSKRLWCAIDRTREMAPRLGVRLHDSSNPLASVASSATQGQSASPMSMGGPSSTHEDSHGSTSGRQNFVLAPLMRNSSSTSMLNSAPIGSALRDNIQGVAPLISNESLSNGAKLRVEFTRLFEAYVSSRYANAANEYAMGKAADSHGATSGQSSELFSYLRELY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB83</accession>
    <name>A0ABR3ZB83_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PRELI/MSF1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002179</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000039">
        <property type="protein sequence ID" value="KAL1897834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006797">
        <property type="entry name" value="PRELI/MSF1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037365">
        <property type="entry name" value="Slowmo/Ups"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11158">
        <property type="entry name" value="MSF1/PX19 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04707">
        <property type="entry name" value="PRELI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50904">
        <property type="entry name" value="PRELI_MSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRELI/MSF1" evidence="1">
        <location>
            <begin position="1"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="241" mass="27009" checksum="A5A2C24FF6A809E8" modified="2025-10-08" version="1">MVLTHSTTHKYSHPFPAVALAYFLRYSSPKLNPFSKHVMGTDTIDCYVDPTTGRLHTTRIHLKKSRIPAAVFKLLPASVTGGASDNKSSYVLEKSVVDIHEGWMETESRNLNYIGVLSIVEKQHYKVPTDFTGPPSISNETNVTTTVIFRSRLGEKLRGMKDSFQTNNENRWASVTGFVGSWGAKGVQRSIESIASTKTLDQLGKSREGMHVVLERLRNTSPMSVLEMVRRERRERQLAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCH6</accession>
    <name>A0ABR3ZCH6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cupin type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002138</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000038">
        <property type="protein sequence ID" value="KAL1898049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-2" evidence="2">
        <location>
            <begin position="182"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="283" mass="30691" checksum="5525C3B3C53ADBB3" modified="2025-10-08" version="1">MSTLMPLLKDLLPMIMPSSVHIQKAPALSSPSSPPPSPHSHPNSKSSSHSRPHAKGREPGSPSGIPPTSPTDSDRDSAAPPRDVLTYSTDAQASVPVNVVLRAASAATESSHLRSVSPAYLADSRIKSSEDESDLDGLDYTDRHTEREAERARMARASQRQSPLRVTNKLVNRSDYMCASAVELDAHANTSIRHHSEQETIIYVISGALILSTKPDLEGDVITNVISRGDFVSIPPWTEHQLRNDSDEKATWLAMRNASSPVTVDLVDWGEEEVDSSLDSDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDA8</accession>
    <name>A0ABR3ZDA8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acetoacetyl-CoA synthetase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_002006</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000035">
        <property type="protein sequence ID" value="KAL1898299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42921">
        <property type="entry name" value="ACETOACETYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42921:SF1">
        <property type="entry name" value="ACETOACETYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyl-coenzyme A synthetase N-terminal" evidence="3">
        <location>
            <begin position="34"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="2">
        <location>
            <begin position="125"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="569" mass="62228" checksum="5E0D37E563A06D73" modified="2025-10-08" version="1">MTDILWTPPHPKDTPMWRFITKVNTKHGQNISNYEGLFEWSINNLDIFWSLVWDFVGIQSSKAPTTVLPSTSMFPRPNFFTGSRLNYAENLLFPANIEIDSTSPAVFSLNELEASALNPDNIPAISLTWAELRQAVKQVSTHLRKSRVNASDVVAGYVGNHSQGLIAMLAAASIGAVWTSLSPDTGVTAVTDRLIQIRPKVLFADDASVYNGKQWPANDKVCTIAKELQPKGLELLVVIDALAKNTADIGTFKIHNIKTVSYSSLLTNNIHEENPMSFEQLPPDHPLFILFSSGTTGLPKAIVHSVLVMLSSITGGTDIISLFGAPCPLLPVKEGSIQCAGLGMDIRAVDSITGLEVPANEPGDLVCVRPFPAQPLTFFSPTSRLEGDKKYYEAYFSHWPQDTIVAGQPGPVWHHGDFVSISDAGSRSLVMLGRSDGVLKPSGVRFGSAEIYNILVRFFAVDVADSVCVGRRREQDYDETVCIFVKMNSGRPFTEKLAADIKRVIRTELSPRHVPGIVEEAECGIPVTGNGKKIEVAVKHIISGQPVTSNASVANPEALNWFRKWALEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDC8</accession>
    <name>A0ABR3ZDC8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000039">
        <property type="protein sequence ID" value="KAL1897808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="71" mass="7518" checksum="0DDAE5ED2CD8ABDC" modified="2025-10-08" version="1">MTGIFTLMKKLSGFCQKKGNRSSRAHSVANDSGIGTPVQDCTTDDGSLIQNGRLGRLQTRSMTLPTTSTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDI3</accession>
    <name>A0ABR3ZDI3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycoside hydrolase 131 catalytic N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_001744</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000029">
        <property type="protein sequence ID" value="KAL1898741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041524">
        <property type="entry name" value="GH131_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34612">
        <property type="entry name" value="GH131_N DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34612:SF6">
        <property type="entry name" value="GLYCOSIDE HYDROLASE 131 CATALYTIC N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18271">
        <property type="entry name" value="GH131_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046934164" description="Glycoside hydrolase 131 catalytic N-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase 131 catalytic N-terminal" evidence="3">
        <location>
            <begin position="18"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="266"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="342"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="396" mass="41802" checksum="804D6A642890AD65" modified="2025-10-08" version="1">MKSFASLLLLGAPALASILWDGRFNDMTSSSDLSKWSWSTPVGSYQYYIHGSGEVTEYVNLSADYKNPADTGSNQGAKITLTNTAYWNGQNMRRTELIPQTTAAINKGKVTYHFSMMRSETNAPSIFREHQIAFFESHFCEMKYGWLSGESGESNPNLQFFAASKSQWAAEWAAGVWHNIAYEIDFDANTVAFWHSTGSDPLTKVVDAVSVTATSDGKDWHMGVLELQRTGYEDADEDFYFSSVYIEDGEVTTGFPASGSTGGSPGSSASSSAASSASATAPTADTPPVANTPAVATPAVATPAVANTPAVANTPAVANTPAGTTPAANPEYAAPTTLSTVTNSAAPANTPAAPEKVNTPATGPSTTGSSYPSSSKTPSTCARRRSLRNKRASKWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDZ5</accession>
    <name>A0ABR3ZDZ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peptide transporter ptr2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_002238</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000041">
        <property type="protein sequence ID" value="KAL1897739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="444"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="483"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="519"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="547"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1897739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="612" mass="67894" checksum="58587E34C451DCF8" modified="2025-10-08" version="1">MSAATPAEDATKAIEAQAAPRYYEQEEVDEKCADKVIPATKLTTSTTDVDYDGQEPTEEELATLPRVSGPIDWAIYTISFAELCERFSYYGSAVLYTNFVNRPLPEGSTTGASHGTTSSTPGALGMGTKAAQAISLTNQFWAYLVPLFGAWLADSKLGRYKVIHIAIAVCTVAHVILTVAATPKVIVHSDRAFACFFIGMFVLCCGTGLFKANISPLLAEQNRDTRMRVEVRDGKRVIVDPAITNSRIFLYFYFAINIGAVSGQISMVWVEKYVGFWLAFLLPTALFLTCPVVLWSQKKNYILAPPTGSVFSKFVKMMVYVMRKSESMLKPSWDLVRPSKVDIASRPTWMTYDDAWVDEVRRGLIACKVFLFLPVFQLAYDQMTGNLTTQAGTMELHGVPNDIIQNLNPISIVVMIPIFDHLLYPGLRKLGIQFTPIKRMATGFIFASASMVGAAVMQHYIYLKSPCGKYANNDHCDPAPINVWAQSLPYILIGISEIFTSVTSFEYAYSKAPENMRSLVMSVNLFMRAISAAMGQAFTPLSGDPLLVWNYIVISIIAFVGGVTFWICFRKLDGDEDKWNLIERSKYMGETEPKASTLQQADVLAEETAKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEF7</accession>
    <name>A0ABR3ZEF7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Inclusion body clearance protein IML2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Inclusion body clearance protein iml2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">IML2</name>
        <name evidence="6" type="ORF">Cpir12675_001606</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Inclusion body (IB) resident protein that interacts strongly with lipid droplet (LD) proteins. Involved in LD-mediated IB clearing after protein folding stress, probably by enabling access to the IBs of an LD-stored soluble sterol derivative that acts as a chaperone in inclusion clearing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Interacts with lipid droplet proteins.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000026">
        <property type="protein sequence ID" value="KAL1899050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019412">
        <property type="entry name" value="IML2/TPR_39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31859">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31859:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 39C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10300">
        <property type="entry name" value="Iml2-TPR_39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="587"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="587"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="610"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00043897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="697" mass="76874" checksum="A6CD1BA89CF3B55D" modified="2025-10-08" version="1">MNRLSVWFRSAESSSSGEPKMSPEDLMRQEMADIEAAFKATELIMDDDMDGAEALLQKTADSCYHALSLAVISFMRAILGFEKEIMTSASAQLNTCETRANADQKRAEKEFTVEMCGFYPPGTEYQLVLAEAQLMGAVVGVLHESITEALRSFYKLRKAYFTLEALMKIETSALNPEKNGNLGPDQDSLFNNPRDVFIHSGTNMCFGILLFMFSMIPPSFSRLLSMIGLKGDRERGIRLLWESTEYSNVHGAVAALILLNYYHGLLGFSDILPTLEHWNDSADAIGYPRAKCEALLVQIQKRYPSSGLWRLEESRLCSTSRNLEGAIAALRRSDAPAPKMKQVSALINFELGLNALFIQDWPLAVEVFSQGLDLNDWSHAAYYFFMASAEVELYRNALAAGDTEKAKEKKKAASEFLAKVSETSGRKKFMAKQLPFEQYTTHKIAKWEERAKTFDIDLIDAIGTSPASEVILLSNGHRRMNAAETKKALDLLSWDRLTAPAKAVESIKQVIDENASKLVCEAALLRTLGRVSEACQILERDVLCHDKSAFKGPNRDDWILPTAHYETAVCYWNEACPQAADMSETALSASPSSLASPSRSTSASPPAQDAPSTAASSNTGISGTNSPGVSIATPKTNSTAPNNLNSNSSCREKAKLCQSHLDKVANWEAFVLDARIGLRVQTGLETMKWFQAKMGWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF60</accession>
    <name>A0ABR3ZF60_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">DNA repair protein rad2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">RAD2</name>
        <name evidence="16" type="ORF">Cpir12675_001449</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000023">
        <property type="protein sequence ID" value="KAL1899333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09904">
        <property type="entry name" value="H3TH_XPG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09868">
        <property type="entry name" value="PIN_XPG_RAD2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001044">
        <property type="entry name" value="XPG/Rad2_eukaryotes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019974">
        <property type="entry name" value="XPG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16171">
        <property type="entry name" value="DNA REPAIR PROTEIN COMPLEMENTING XP-G CELLS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16171:SF7">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00066">
        <property type="entry name" value="XRODRMPGMNTG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00485">
        <property type="entry name" value="XPGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00842">
        <property type="entry name" value="XPG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG N-terminal" evidence="15">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="XPG-I" evidence="14">
        <location>
            <begin position="863"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="120"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="392"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="517"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="573"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="700"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="770"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1124"/>
            <end position="1193"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="826"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="132"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="517"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="706"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1130"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1148"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="1178"/>
            <end position="1193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1899333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1193" mass="135197" checksum="323AAF7EB83C394C" modified="2025-10-08" version="1">MGVTGLWQVVQPCARPTNIATLNRKRLAVDASIWIYQFLKAVRDKEGNALNSSHVVGFFRRICKLLWFGILPVFVFDGGAPVLKRQTIQNRRQRREGRREDASRTAGKLLTVKMQRLAHEEAERQKKRRRSQNKDQVAEKQVDQEEPEIDFQNAVYVDEIGLSPQERLRKRKFVKQDPYHLPYLEGGVGARANPEDPRIMSVEELEEYARQFNAGEDVDLYDFSNIDFDGDFFQSLPAADRYYILNAARLRSRLRMGLDKEQLEIMFPDRMAFSRFQVERVQERNNLTQRLMKELGMTGLDLTVDGGRRIAGDKNREYILVKNDSAEGGWALGIVNRDKDIGKAHKPIDVDALQFEFQGKDGYSDEGEVEDFEDVPIEGLNRLPKTRALAARALQQSQTAPLQDSAKKKKDEEGDGDEDEGLFVSNAPLQIERGFPENQYTAADKYEQDDIDIAIALALETQHKAMISTKVPAYEEIEPNDNLTDVPVWKQKAVEMPQSLSRPITKSTLNTLNQRANIEVSNPSTREVAQPKPANDSDSDSDMDFHAALAMSRKAHQHKPATAPLPMISMKVNKPSSRSLPFPKLDWTAKKKIQSPKKTPGPPDEGSSLELGGGFVPDSHNNDKPNNELPPWMLDDTDIIESLKKQEEAQRQMDTKDRDHALSEQQFYGDLRSRQADFIEVLSDSDSEIELVDAISQRIVNDKESIPSTTLNLQPQPANKPPLELDVEHSKQDSPEPEFEDVVAIDTATNKASTPESPRESSVHEFEIDDEELFGKGAQNSDNEDSNLDDFSDLEDEQLLIQMAEEAEEHARFANQVQNRPEGTNHASIEAELRQLRDEQRRERRDADEVTETMGLQCQDLLRLFGIPFITAPMEAEAQCAELVRLGLVDGIITDDSDTFLFGGTRVYKNMFNTNKFVECYITSDLETEMSLDRDSLISLALLLGSDYTEGLPGVGPVTAVEILSEFPGKDGLEKFKEWWEDVQLHNRPHDADKSAFRRKFRKSHLTKLFLPASFPSKTVYDAYIRPEVDDSDERFQWGVPDLDGLRKFLMTTTGWSQDRTDEVLVPVIRDMNRREREGTQSNITKYFQGGVGAGARDAFAPRQRVQGSKRMAKAVDRLKQAVTGEITDESSAPGNATTTSTKRKRPEKTVQRIDDESEGYKEGEGEDPAHNDDYQAVRRRRKASRKASQRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF72</accession>
    <name>A0ABR3ZF72_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Inner centromere protein ARK-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_001728</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the INCENP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000029">
        <property type="protein sequence ID" value="KAL1898725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005635">
        <property type="entry name" value="Inner_centromere_prot_ARK-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13142">
        <property type="entry name" value="INNER CENTROMERE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13142:SF1">
        <property type="entry name" value="INNER CENTROMERE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03941">
        <property type="entry name" value="INCENP_ARK-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inner centromere protein ARK-binding" evidence="9">
        <location>
            <begin position="1348"/>
            <end position="1404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="69"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="583"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="694"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1024"/>
            <end position="1370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="203"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="287"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="336"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="390"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="419"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="481"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="601"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="616"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="732"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="961"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1054"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1071"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1150"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1250"/>
            <end position="1265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1291"/>
            <end position="1306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1318"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1343"/>
            <end position="1360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1898725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1459" mass="163020" checksum="0C66E2B4DDBD5DD7" modified="2025-10-08" version="1">MAMRGARLPLGSAKWLTEERNSAVKMADQEVEEFSFSARNDFDWLNEHMAGIFDENEINVAGIFKTPGKMLGKTPRTTRRRNPAPTLDNTAAVAPGAENRLPLSDIFTSTTPTSAPNRFTQQLSHRTQSPPVDMDNPDPDSSIDERAVSPSPIRPAMSPAVGVPKSKSRPPTIDNNASYPDIPAQQKHNEQNVPDSPSLRPLKNSQMQRSMESPISRCQKDPYPSTERPVSTVRELIKRANSPQPSPSAVSPRLARSDSPFRRAASPTVRNPAPVLISPSRSPAAMTLSTRLSPVKSSPTKAFSAHAGSIAKQPHTAAMPTSHDEDGDVHMPQAQDGEEDHDDKEDDDDANARSPSPSPARPIMRKSSLNFASLPAREPLAHKSTGARVSRTSNLDTLRNSYYPRTTPGKSFGGTFYREEDEDDQDAMNVDDESQDKGSSNDPPSHNLTYTQRLQDQINRLVESQPKAARHSKSIHGLATAHSQQQPASQPIVTKPTTAPVSPQRKTGPSPVSTTPGAFPGAEADDDDWVENPPTENTTFSPPAASIEMKSVADDFLVAKSGHIDSPFGSPICSSMPDRAMSVTPAHTKSASVSMMPESNPALSQIKAQGHNKTASVSGSSLSSLQDTAASGSPLKSPARSLRESPLKQVKNKLSSILKGSKGLLASSAVASAEGKSLMSPSRVMVNTLQSTDSIDAIPPSTSPEGLYPDISCRANETHAVSSPRPVRRTRASAERERLEKQQQRDVKLMAEQMNKLERVREQEREKARLHSQEQEREKERERERRREQERERERERERQREKEKEKEREKERAREREREKEKERERERVLEAERREQELERQRELELERERQLDLERERELERERELERERELERERELERERELELEREHERELEREREKEKLTRQERPLPPRPTTASNGESERPKSRSALPSPRKLMRPRQAPLQHHTDDEVDVAQTPARSTASTARPPTSHSVRTKEIKRPTKPMAGKMRPEPPKHFVVKPTSLYHPSTAVLSATLQDTLDAPSIPRPQISLKSSQGSLKEKDSTQSLKSSVASSASTTRSRTVDMTMKKREQEEQRRKESKAELARRRIAQQEEARRLEQQREEERKALEAKKKAQRQAALERAKQTRAPPPAVRNHPNGPPEYSQPQQSSRPASRVATAPPPEIARPKSSMKVTLSSAKRQLEEEKNTYSGRNGPSYQAKDSKRRRTGEDFDEDEFDVQPAMKGPPVRPSSAFKRDLPSTKSVYGSAAASSYGQGTQAAPGPARDLFKSNTTKPGPHDMSQFSKGAIPFAPNNNGAPNGPTNVFKTPGRTALPSNSKSVAKSASRPSPRFQNGENIELPEIETDEDEDEDDDEENARNMAVAPWADSPDLRRALIRQETMDPSLIFGPPAPLNMEEVFSKNKDRWNKFRARTSSANWTGADRLTEEDIRKDMAARDRIRRDGGWSYDLSRDLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFH3</accession>
    <name>A0ABR3ZFH3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Metal tolerance protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_001422</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000022">
        <property type="protein sequence ID" value="KAL1899386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1350">
        <property type="entry name" value="Cation efflux protein, cytoplasmic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050291">
        <property type="entry name" value="CDF_Transporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840:SF4">
        <property type="entry name" value="CDF DIVALENT METAL CATION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840">
        <property type="entry name" value="MITOCHONDRIAL METAL TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="358"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="395"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="8">
        <location>
            <begin position="291"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="9">
        <location>
            <begin position="507"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="200"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="233"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1899386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="581" mass="64608" checksum="49B9FBAB0EDB2058" modified="2025-10-08" version="1">MSSLKRTRSTSSVHSRTVFWHPSDDEDLAGSPSSPLAQLAAGRIVMRTPDPDEDPRRIALDGRRLSQIIAGSGMRSMRMIGGNQNPRYNWEQYWTKQEKLQQYSPPIREYYERINDLIQQYLFIDKLLDSTIPYEMLDEYSTEMHASAFHSVDIPDTIHENQSDEQSPTSDSYGSIGQKAAMKMPVANERNDATETTGLLAPAADVAPSPTAPRKRTPKDIFRAPEDPPITPNGPTTGPISIGQRSSNAGGTSTCNDIEAIAGNIDAPIASIPWVEDAEIDSDDPIVEVAIWVNFVANAILLAGKLMVVLSVPSMSVLASLVDALLDFLSTFIVWTTTRLVARSQSDNEQYPAGRRKLEPLGVLVFAIIMVMSFFQVGFESVNRLLAPDHSILELGLPAILIMLCTIVIKGAVWLWYRMVKNSSVQALADDAITDVVFNTGSILFPIVGFYARLWWLDALGGLFLSIYVVYNWSDTAMHHARNLTGFSADPDERNLLLYLTMRFATTIKQIQNLRAYHTGDKLAVEVDIVLPSHTPLKDSHDLSEVLTYFLESVPIVDRAYVHVDYLPYHQPTHISGSRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFT3</accession>
    <name>A0ABR3ZFT3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein YOP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">YOP1</name>
        <name evidence="7" type="ORF">Cpir12675_001580</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000026">
        <property type="protein sequence ID" value="KAL1899024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004345">
        <property type="entry name" value="TB2_DP1_HVA22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300">
        <property type="entry name" value="HVA22-LIKE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300:SF161">
        <property type="entry name" value="RECEPTOR EXPRESSION-ENHANCING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03134">
        <property type="entry name" value="TB2_DP1_HVA22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="170" mass="19132" checksum="7307B651731D3593" modified="2025-10-08" version="1">MSAPQDRVNAIVASIDKDLSKYPAIRNLEKATGVPKAYGAIGFISLYLFLILFNLGGQLLTNLAGFVIPTYYSLDALFSAGTDDDRQWLTYWVVFSFFTVLESFIQVVYWFPFYFTFKFVFLLWLSLPAFRGAELVFNSFMAPMLAPHFRQVSTASNLRSQAAAGLSKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFX1</accession>
    <name>A0ABR3ZFX1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Mitochondrial fission 1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">FIS1</name>
        <name evidence="13" type="ORF">Cpir12675_001382</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Has a role in mitochondrial fission. Has a role in outer membrane fission but not matrix separation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the FIS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000021">
        <property type="protein sequence ID" value="KAL1899613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12212">
        <property type="entry name" value="Fis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016543">
        <property type="entry name" value="Fis1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033745">
        <property type="entry name" value="Fis1_cytosol"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028061">
        <property type="entry name" value="Fis1_TPR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028058">
        <property type="entry name" value="Fis1_TPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13247:SF0">
        <property type="entry name" value="MITOCHONDRIAL FISSION 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13247">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 11 TPR REPEAT PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14853">
        <property type="entry name" value="Fis1_TPR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14852">
        <property type="entry name" value="Fis1_TPR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008835">
        <property type="entry name" value="TPR_repeat_11_Fis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 11" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR008835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1899613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="153" mass="17455" checksum="C8DEA55C07573C21" modified="2025-10-08" version="1">MGDELPYALDVETPLKPDELQVLRDQYEKEGDLVGIQTKFNYAWGLVKSNSRADQQHGVRLLADIFRQSQERRRECLYYLALGNFKLGNYEDARRYNERLLENEPTNLQAINLRTLIDERVAKEGLVGMAIVSGIALAAGVVGGFILRNSRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG64</accession>
    <name>A0ABR3ZG64_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">prh1</name>
        <name evidence="10" type="ORF">Cpir12675_001303</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000019">
        <property type="protein sequence ID" value="KAL1899718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF118">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="121"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="356"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1899718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="800" mass="89793" checksum="5E5F22AD8D672D85" modified="2025-10-08" version="1">MSSEPPRKRKKKSHDPNVVMLGGKPLNLAALLDEPPKRKNPEPDPKQTPTPATAPSNGNEPHASTSPELSHHRNSLGSFKNRPGRGTYGKGTLRDSRWKENPVLLKTRQKLPIWAYRDTIRGALTRNDTLVVVGETGSGKSTQIPQFLYQEPWCQRRKAKVPNLPEPINVGGIIAVTQPRRVAATTLAHRVAQEAGSPLGRPEGLVGYSVRFDHNVPKGTKIKFLTEGMLLQELLQDPYLRQYSAVIVDEIHERSVDVDLLSGFLKKIRIEGMENRGGVPLKVVIMSATADVDEMKDFFSESTPSEEPCNQNKECKKNPSKIDFMPAEEQRQVEVLHVKGRQFPVDLEHTTRPVNDLQDQLLKTVFRVHTEEPFPGDILAFMTGQEDIEAAVKLIEEYGETLAPNVPRIKAFPLFGQMSMEAQHAAFQPLKEKYTRKVVLATNIAETSVTVPGVRYVIDCGKAKVKQFRTRLGMESLLAKPISMSSAIQRAGRAGREGPGKCFRLYTQETFDSLEERDLPEILRTDLVTAILTMKAYGIDDIQAFPLIDMPEVEALEHALMQLCLIGAIDKVGHITEEGRKISKLPVSPTFGVVLLNAAKPEFDCLLEVIDIISCITSGEDIFQHIQTEEVREEVEEMRKQLFRREGDLITLLTTMQLYASENTDRTTWCQQRRINMRNMRQAMKIRKQLRGLAIKMKLLKEAPPADPQPFVPPSPEGADSILKCFLKGFVFRTAMLHPDASYQTVVGKQNIAIHPASVLHGRKVEAIMFLENVFTQKNYAKKVSAVRADWMMGEWKTGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH13</accession>
    <name>A0ABR3ZH13_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mitochondrial outer membrane transport complex Sam37/metaxin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_001471</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000023">
        <property type="protein sequence ID" value="KAL1899355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050931">
        <property type="entry name" value="Mito_Protein_Transport_Metaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019564">
        <property type="entry name" value="Sam37/metaxin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12289:SF41">
        <property type="entry name" value="FAILED AXON CONNECTIONS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12289">
        <property type="entry name" value="METAXIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10568">
        <property type="entry name" value="Tom37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="341"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Mitochondrial outer membrane transport complex Sam37/metaxin N-terminal" evidence="8">
        <location>
            <begin position="24"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1899355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="420" mass="46421" checksum="268CF8232BBEB6A1" modified="2025-10-08" version="1">MPDGEFVLHIWGPAFGLASIDAECLAAVTLVMQTVSREGWKKWQIVASSDPSVCSTNMLPALHHNGSWICGYRAISRYLKSTALTQSGHLIPQDPDAVAFSAWLSSKVAVLLDLSLYVSASNWSSVTRPAYSDILPWPLTWSIPPMLRRDAIQRAERQGFDNLDIDIESQKTAGGKVAAFPTSFDWRLPSMEKKSVLREMTPEQQASIKLYDFSREALDVISRESKSFLVDGHVSPEGCLAYAYIALLIKPDVPQPWIRNIVMSEYPKLVEFTNNVDALNKSTASRVQISTRPRTKLAIAASLCHQLVQEIPGLGDLYLQEWRKNMLKSTASGRPKWPKRLIVSSAVAIGTLGSLYFYLRPFYPLGRPMYLWNSPSISRLGQFGELGAMLGIAMGGVQAAGGYSSLNQRPGVLEDVAIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH71</accession>
    <name>A0ABR3ZH71_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001256</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000018">
        <property type="protein sequence ID" value="KAL1899754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046265497" evidence="1">
        <location>
            <begin position="18"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="188" mass="20974" checksum="F9C8F0ECA3C83067" modified="2025-10-08" version="1">MIPATTLILALASAAFASPVSRATEDYMPLEISEMEMSCAKTAPADLLFACTLNYNLRDPNAEAANPSVNPKVTCTHRWNWDGQTAEKGPLNTYTHSTLECYSDGNGRNVKSSLYKFTGPENIQLSFLSSYYKNYETKSFRNLFFEHVNIEALTPAEDSELLKTWSLMQTQTFQDPSVTAYDPPTNSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHU2</accession>
    <name>A0ABR3ZHU2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_001391</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000021">
        <property type="protein sequence ID" value="KAL1899621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00747">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="9" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046073571" description="CFEM domain-containing protein" evidence="10">
        <location>
            <begin position="17"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="11">
        <location>
            <begin position="2"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="45"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1899621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="152" mass="14799" checksum="A3FCDBC259F0CDFE" modified="2025-10-08" version="1">MKFTLALLPLAAIATATTTSLDVTDYFPSCSLDCLSQAVSNSSSCSLSDSVCMCTNAIDENLAVKTNSCMIKDCGSTVAFTDVLSAADNFCRAALSGSTASAGVASLLGTSTATGTAAASATGTSNSTATAGSAANIAPAIMAIVAAGMAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIG0</accession>
    <name>A0ABR3ZIG0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_001377</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000021">
        <property type="protein sequence ID" value="KAL1899608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF81">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="174"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="87"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="115"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="158"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="716" mass="79029" checksum="940B859E35BD234D" modified="2025-10-08" version="1">MNRQCSQVPDLSPASAASNPLAPTSSSPETSPNTDRSALYASFQQFSPAAYPPETLYSTKPVIPGHVYFPPASIPSIPPPIVQPSLAFTSAPTGQPAMPTNSLSSLVTMRPTPPAASTSKQEQAGQNGSHDDLRDTSSSAGSPYGDGPGMVNCSASRHDRKKNTKQRRNKPTLSCFECVERKTKCDRGRPTCFACIRRGSFCAYDRVAQILEESHRTSANGPRMTRPSSKRLSQSKYSIIPNMADHSLIGSKSSTSQGAVALSTGLMSNMPFSVSSGSNVFGIGAQHPFANYWTCKGGLPEVISVIPTKAQTDALMARYFECVDPVYPMIHRQTFYADYEHFWGMADVDRSHVDASFVALLFVMIAMGAQFVEDYPCAEKKNMAEFYASASHQSLRVYSYLSTASVTSIQAMVLITYFLINDNHVTDGWAFAGILTRQSYAMGLHRDPNIVTPNASLLEKQQRRKLWQAVLLQDTFLTILLSLPPTATHTDVTVDSLIEDGSSIANSDPTDTLYIKCSWTLANLVQESICSPRSLDLPICTTARHKTKLINEFKSVYRSFPDLFRCCDKATLTARTATEGRAVRQILWLTSNFFHNLMLVNASMSDEVSVNVRGTLEAAHDAIMSFFLLFELFESEARMWWAFNHRAFLEALCIGAVLKMHAGDRENIDETIYDRGKNDLLRMVEIMHRMGERGSELARTRAAVLNEYLADLKGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJR9</accession>
    <name>A0ABR3ZJR9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fatty acid synthase subunit alpha</fullName>
            <ecNumber evidence="3">1.1.1.100</ecNumber>
            <ecNumber evidence="4">2.3.1.41</ecNumber>
            <ecNumber evidence="2">2.3.1.86</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="primary">FAS1_1</name>
        <name evidence="24" type="ORF">Cpir12675_001073</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24 25">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>a fatty acyl-[ACP] + malonyl-[ACP] + H(+) = a 3-oxoacyl-[ACP] + holo-[ACP] + CO2</text>
            <dbReference type="Rhea" id="RHEA:22836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
            <dbReference type="EC" id="2.3.1.41"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>acetyl-CoA + n malonyl-CoA + 2n NADPH + 4n H(+) = a long-chain-acyl-CoA + n CoA + n CO2 + 2n NADP(+).</text>
            <dbReference type="EC" id="2.3.1.86"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 21">Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="3"/>
    <dbReference type="EC" id="2.3.1.41" evidence="4"/>
    <dbReference type="EC" id="2.3.1.86" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000015">
        <property type="protein sequence ID" value="KAL1900073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004321">
        <property type="term" value="F:fatty-acyl-CoA synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00828">
        <property type="entry name" value="elong_cond_enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08950">
        <property type="entry name" value="KR_fFAS_SDR_c_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="entry name" value="4'-phosphopantetheinyl transferase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00101">
        <property type="entry name" value="AcpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002582">
        <property type="entry name" value="ACPS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040899">
        <property type="entry name" value="Fas_alpha_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047224">
        <property type="entry name" value="FAS_alpha_su_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026025">
        <property type="entry name" value="FAS_alpha_yeast"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041550">
        <property type="entry name" value="FASI_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050830">
        <property type="entry name" value="Fungal_FAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004568">
        <property type="entry name" value="Ppantetheine-prot_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00556">
        <property type="entry name" value="pantethn_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10982:SF21">
        <property type="entry name" value="FATTY ACID SYNTHASE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10982">
        <property type="entry name" value="MALONYL COA-ACYL CARRIER PROTEIN TRANSACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18325">
        <property type="entry name" value="Fas_alpha_ACP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18314">
        <property type="entry name" value="FAS_I_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000454">
        <property type="entry name" value="FAS_yeast_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="4'-phosphopantetheinyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="24" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="16" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="15" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="13" id="KW-0521">NADP</keyword>
    <keyword evidence="14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 21" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 21 24" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="23">
        <location>
            <begin position="1113"/>
            <end position="1649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="96"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="22">
        <location>
            <begin position="101"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00048237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00048508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00049541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="PIRNR" id="PIRNR000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAL1900073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1880" mass="206730" checksum="191AC61D4C2585CC" modified="2025-10-08" version="1">MRPEVEQELAHTLLIELLAYQFASPVRWIETQDVFLAEKTAERIVEVGPADTLGVMAKRTLASKYEAFDAAKSVQRQILCYNKDAKEIYYDVDPVEEEPEAPTASSSDTPAAAPAPTAAAAAAPAPSTGPAAAVADAPVQAIEIVRALIAQKLKKPLLDVPLGKAIKDLVGGELHNLLIFNTLDTSIVLDSNVSLLLGKSTLQNEILGDLGKEFGSTPEKPEDTPLDELGAAMQATFDGQLGKQSQSLIARLISSKMPGGFNITATRKYLESRWGLGSGRQDGALLLALTMEPPSRLGSEGDAKAFLDNVTQSYAKNSGISLSTASADGPAGGGAGGMMMDPAAIDALTKDQRALFKQQLELLARYLKMDLRAGDKAFINAQQTEKVLQSQIDLWNAEHGDFYASGITPSFSPLKARVYDSSWNWARQDCLTMYYDIIFGRLQVVDREIVSQCIRIMNRSSPTILDFMQYHIDNVPTERGETYKLAKELGAQLIENCRDVLNAAPHYKDVAIPTGPRTTIDAKGNLNYEEVPRASCRKLEHYVQQMSEGGKISEYGNRTKVQNDLQRIYKLIKQQHKMSKTSQLEIKTLYSEVLRSLAMNESQIIPKDKDKHIKKAMSNNKGKVETIPFLHLKRKAHHGGWDYSKKLTGQYLNCLAQAARDGVTYKDRYALMTGAGAGSIGSEVLQGLISGGAKVIVTTSRYSRQVTEYYQSMYTRYGARGSQLIVVPFNQGSKQDVEALVDYIYDPKNGLGWDLDYIVPFAAISENGRQIDDLDSKSELAHRIMLTNLLRLLGAVKRQKHERGFETRPAQVVLPLSPNHGTFGNDGLYSESKLGLETLFNRWHSESWANYLTICGAVIGWTRGTGLMNGNNIVAEGVEAFGVRTFSQQEMAFNLLGLMSPAIVDLCQNEPVFADLNGGLQFIPNLNEIMTKLRSDIMQTSEVRKAVSKETAIENTVVNGADSEALFKRKVVQPRANIKFDFPQKLDWDSEIAPLNAKLKGMVDLEKVVVVTGFAEVGPWGNSRTRWEMEAYGEFSLEGCVEMAWIMGLIKNHNGPIKGKPYSGWVDAKSGEPVDDKDIKSKYEKFILEHSGIRLIEPELFDGYDPNKKQLLHEVVIEEDLEPFESSKETAEEFKREHGEKVEIFEIPESGEYTVRVKKGASLWIPKALRFDRLVAGQIPTGWDAKRYGIPDDIISQVDPVSLFVLVGVVEALLSAGVTDPYEFYKYVHVSDVGNCIGSGMGGSTALRGMHKARFQDQPLQNDILQESFINTMSAWVNMLLLSSSGPIKTPVGACATAVESVDIGYETIVEGKARICLVGGFDDFGEEGSYEFANMKATSNAVDEFAHGRTPKEMSRPTTTTRNGFMESQGSGIQIIMTAKLALEMGVPIYGVIALTTTASDKIGRSVPAPGQGVLTTAREHAGKFPSPMLDINYRRRQIDLRKKQIKQWQESELEYVYDEVQAIKAQGADIDEKEYTSERIAHINKEAARQESEVLTSLGNHFWKKDPSIAPLRGALATWGLTIDDLDVASFHGTSTKANDKNESSVICQQLEHLGRKKGNAVMGIFQKYLTGHPKGAAGAWMLNGCLQVLNTGLVPGNRNADNVDEVMEKFDMIVYPSRSIQTDGIKAFSVTSFGFGQKGAQAIGIHPRYLFAVLDKATYEDYTNRLESRQKKTYRYFHNGLINNSIFVAKSHSPYTDEQLTSVLLNPDARVTEDKKTSELNFPSNFMKLSEKTPTTAQNRETNEMIEVLAQGVQSENNKVGVDVEDISAINIDNDTFLERNFTDEEIAYCRSASSPQSSFAGRWSAKEAVFKSLGVESQGGGAAMKEIEIVRSETGAPSVKLSGGAAAAASKAGVKSVSVSISHSETQAVAVAVSTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJU5</accession>
    <name>A0ABR3ZJU5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Kelch repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_001014</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000014">
        <property type="protein sequence ID" value="KAL1900330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46228">
        <property type="entry name" value="KELCH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46228:SF2">
        <property type="entry name" value="KELCH REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_4G14350)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="454"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="561"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="668"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="594"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="690"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="737"/>
            <end position="764"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1900330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="764" mass="82577" checksum="6F5F2DD2F6C0EB41" modified="2025-10-08" version="1">MGYMFTLPLNTFVNFTTANFSDIIKTTSKARGGSGNAAVGGAPNYYSGALLGNSAEFFLYGGLLARTDAYTLPEEDDVLGYQKFEYGADRDFATNLNSYKTDPGTNRYVTHGAGATVNSEWKAFYFSGLRSIAGPIYRLVSVSQSATSWTSPADFLITLETDESNQLTHKWTNSSLPDDVKGRAAGEFVFVPVGENGIMVAVGGVTYPEFTNATGESPNPDLSTSEGRSFHETIDIYDIGSQKWYRQNSTLIDTPPTLAYGCAVMGAASDGSSYNIYYYGGYTALSKTDQFSDDVWVLSLPSFTWTKIYSGNSLHGRIGHQCFQPYPGQMMIIGGKPATTSSTSSTDLNRCLEGNIIQLFNMSSLEWVDAYDPAKQTNYTIPDEVSNVIGGNAFGGATRTAPDSGWSDDELERLFDTAYPTSKITNYYPYSAAIKTVEPTSRDSGSSSGISNGAIAAVVVCSVLALSFMLGLFIWWRRRRLAQMSETGTSATYTSNRIWAWILGTPPLTTTTTAAKAITETTEASGILDEGSLSPVSAMSVPVVVPVFHHEMDASVLPELEDTSRPELGETGMTPVKTTERKFPKTANIPRSPLSMSPTGLSENDRNSFISQSEISSARNSAMSPQTPSPPQSPTIPDTAAPLHPAAVPRTVSDVSNISDREAKHLRHISDVSSAGDFPETPIISPIKAAFKEPVIEEQPEKEKTLPESSEAAAKDFSEENVAAAKAPYTSSARRSVFHESRDDLGEIEPPKKSFSEEKTEGNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLD4</accession>
    <name>A0ABR3ZLD4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RDRP core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000590</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007855">
        <property type="entry name" value="RDRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057596">
        <property type="entry name" value="RDRP_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079">
        <property type="entry name" value="RNA-DEPENDENT RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079:SF55">
        <property type="entry name" value="RNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05183">
        <property type="entry name" value="RdRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RDRP core" evidence="2">
        <location>
            <begin position="555"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1419"/>
            <end position="1441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1526"/>
            <end position="1568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1613"/>
            <end position="1668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1419"/>
            <end position="1436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1613"/>
            <end position="1625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1626"/>
            <end position="1635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1681" mass="185265" checksum="98FD6CFBDE6FC252" modified="2025-10-08" version="1">MTHSGRGKNHVSHDISSGNNRISKSHNGDSHDKAKTTSSNSKKSKKTDPATTSSTARSGPASKSNYANIPRPIPIPQPRPLYVSTLSISPRPTAGWKSWVGALITLIGLPGSANPRQVFTNLSKHGGEISRIDFFASPARSPSPTSGAAPLNQARVIFEKLPNTAFWSSGRLTFRGSCGCPNWIVVVMAQEFKMGVSRIKSPVRPEVTYPAIITLRPQSTTFGMMTKHNVLMSMKTVMTDQVDLDCRQAIEIDLPRKQIRVFFGLPRAKIGQTSRAYKALISFDNLDAIYYAYENSGLDFGDQPESSPLFLRLTLQCPPLYFWKRFDTDAISPKRGISFDTRDSWIRLVNISMGGGDQETVPLNFHTSSSLPSFIDLGKWRTLRFSLSHMPNRTETLNALQDFRLPLLPEPKPLAIVPRVNNPIWSILDSPANTLLSASKNNNTAILSVMNSSPHKLPWAVRYQLEVCVTRGIFQEHSINQDFINQLAAKGEHEARSLLEQAADLYDRSATSKTLTLIENPYDILAQDNSLLRGSRVSIRPRIPHYCALVRKAVVTPTTVYFMTPTTESTNRVLREFRHVHDHFLRVQFSDELLNGKLNSGNTSHKNNNVYVRIFHIMDQGIRIGDRVFKFLACGNSQIREGGAYFFADTPEITRNDIRAWMGNFSSIRSIAKRTARLGQCFSTTRAIRGVSMPVISRIADIERNGFCFTDGVGKISSFLASIIMEEMELFTVPGEPIPAAYQFRMGGCKGVLVVSDDVSGMQVHVRKSQEKFHSVFNGLEVIRVSQFSIATLNRQLIVLLSSLGVPDEAFEKLLEEQLTAYETAMVDLPTAMTLLTQYVDENAITLQIADMARAGFLNKANREPFVLSLMVLWRTWSLKLLKEKARIVVPKGAFLLGCVDERGLLRGHSIASEGSKSHDISQLPQVFVRIPEPDPRRRSQYVTIEGICIVGRNPSLHPGDIRVVQAVNVPELNHLTNVVVFPSTGDRDVPSMLSGGDLDGDDFFVIWDETLIPPEWNHKPMAMSPVQSVESNKDIRVCDMQAFFVKYLRDDILPLIAHAHLALADFQGAKSKKCLQLAALHSRAVDFAKSGVPAELPPKLYPERWPHFMEKKRGSTYHSLRPLGIIYDRVQTIEFTPFYTNDMFKSILSQPALPEHLELARQIKINYDIEMRRLMGQFEISTEFEAWSTFVLSKPRVGNAYKMQERIGSEVSVLKRTFRELCVEQVGGALSFTAVKPLLIAMYHVTHEDLQASLAKLRSKAEAEARPGPDSDVNAKLSADGNLNFDLRDVPLISFPWLFPEYMCQLTSSKDKADDAFTFTQTGAAELRLLVKQRRAVVGPTKRESTEAISMEAKSQNIIPTGQLVRAHDTTVAAPTEDIAAFSDSRKPSFPQSFPPVLDSGTASSVGMATPISMSPCTSASIGSTNAATASTNTSVSDPSGFFDRPLSKIALQTAETLNTGPPAPAKPTLLQEPVPDNPPLTTLCFNSSNPMSPLAPTTVASPNHAIANARADSVAISKAATGDVTKTTGRKTPNGGDMIDTSDTKSTQNLPRPPLTNPQTPAPIYDLLSDYDLDTSTSASKLDFGPVLEPLSSNQAAQTPAHLLDTSENTSVPLLDMNNNTPKPLSGSSPGLSDVDQSDDTDGGVKLDPQSSSSSSTEERIAATTKPAWKKWLELEGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLI1</accession>
    <name>A0ABR3ZLI1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cargo-transport protein ypp1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_000517</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in endocytosis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YPP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051722">
        <property type="entry name" value="Endocytosis_PI4K-reg_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23083:SF464">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT DOMAIN 7, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23083">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN, TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="698"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="754"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1041"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="785"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="817"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1057"/>
            <end position="1077"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1209" mass="132306" checksum="8919FE8C855CEF72" modified="2025-10-08" version="1">MSTAKAQNYLALLEIARCEGNWSAVPELVRKVRKHAPERACLTLAALTEAQIAEATQSSTENSTPTSDTLQVAQQLPKLVEAIENESTYPQDRFQATICAGWLHWVVGEYSLAALRLPNQIDEDYPLLQNPSEWTTVCALKAAYLKGNCAARTSQPLDALSVFETGLAAMDGVWGANKQPRRQLRYWAELFLSEYSMLSSQVLNRQEKALQDPNSLSGFRSWSRYWESLVGPVIGGQGFRGSVPRRRIWYEYYGALSNILELDLPLPTDHVKPINETSARTQLRIELKKTESAYEALLLDETQFPKADEEREEVEAFVQLAMKNWSILCGRGWKETDLGQGGRASISRGVLDILYRAATKTYHSTAILRHLVTVHLAVAEFDIAFKAFDSYMEVVKKAKARVEKTGVAEPSLDDDNTVLKTMSQAIVALCRYGGASAIEKAHDLGRELEDTMAHLPQLQPASEVATPIDPTHEIGIHTKVAGDTLAFAWQAIGLAHASWSRVTPDAPSRTEIQAKAIRSLRKSLSPAFGRSRDVQSLYSLGLLLAERRDIGAAIEVVKAALVSTKSEEPNAALVYGSYWQERAFIPVWHLLALLLSARQDFMMAARACEGAFEQFKDPSVLFGSQQVFNSEHLKAQAAPQASFGLVDDLDDAEREAILEVKMTQLALIELLEGPEIAVNASYELITLYSRLFGSTATTPKTSLQPPPAQIPPKSSSGTVRSFRGSIFGPRAGKSPSPAVGATALPVDVVSAESRPLSALPGTPGLASNGMNPSTGAPTPAIQITAEKNGSTQRSTSAKPTGGRSSRRSSIRNRDRSASGGKRASSSGPNYRNVPDGEVFFSPEGNLSSDAFALTSRPQASIASAFVRRQNVGSLDTFISTKAKGLDHLVDHAIDGVFSLPPPLPPIVFSKDEEKRQRSVILIRLWLMVAGFYRRADMVEDAKGAVAEAQKLVQTLETELTNDVTGSLILKVPKWAEKRSVDELWADVWAEFGNISLTNDAPLDARRNFESALTYFPNHAAGIVGLSNILLDIYTEDLVPVSHEPSSHDSYSHSHNSVTTNSELRSNSSKNKGTSPLTNEPLGLGPNRPIRLPASFSNAESETNLASESYPDLKHATTLPHKYFSPEPRPSSLPLIDRLAARDRAYGLLSALTKRGSGWNNSEAWFALSRAYEESGQPEKAKDVLWWCVGLEEGRAIREWSVLGDDGYIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLZ0</accession>
    <name>A0ABR3ZLZ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Acyltransferase MbtK/IucB-like conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000744</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the lysine N-acyltransferase MbtK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019432">
        <property type="entry name" value="Acyltransferase_MbtK/IucB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31438:SF7">
        <property type="entry name" value="ACYLTRANSFERASE MBTK_IUCB-LIKE CONSERVED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31438">
        <property type="entry name" value="LYSINE N-ACYLTRANSFERASE C17G9.06C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13523">
        <property type="entry name" value="Acetyltransf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01006">
        <property type="entry name" value="AlcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyltransferase MbtK/IucB-like conserved" evidence="2">
        <location>
            <begin position="261"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="450" mass="50561" checksum="E8C9B2AD1AB1D124" modified="2025-10-08" version="1">MVPSTQQLSLSTAATGSPILALPHPYLSAYTLRETSDVQYAIDETGAPKSVLPAPVVRSDIRLRDFTELKSSETPVGSNNSAWARARRSPLSTVSWSASSPPSMAQLWLAIYVLFTIRPSVEHFRLGLQGNGASVLCAQVKAVALAVDHPQQIGGSESDSTNTGHTTLLVLRSMFWQGAGSPFGPRSVWTPSESLAREGLALDTFPITPLQHTMTVTSAGDPFNPQCYQKTWHPLRPSKPVPGTVVYSRYIPHLNENFSMIAIDYHNAEHLKLFHEWQNDPRVSQGWNETGTLDEHREYLRRIDEDPHQFSVLARFDDTCFAYFEIYWGKEDRLGAYYTADDYDRGRHSLVGDVRFRGPHRVSAWWSSLMHFLFLDDCRTRFVVGEPKETNNTVVAYDLMHGFGVEKFVDLPHKRSAFVKCSRERFFQICPLGENEKVVGGMRIGLVAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM97</accession>
    <name>A0ABR3ZM97_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_000660</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000008">
        <property type="protein sequence ID" value="KAL1901170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057454">
        <property type="entry name" value="Bud3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051092">
        <property type="entry name" value="FYVE_RhoGEF_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673:SF261">
        <property type="entry name" value="BUD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673">
        <property type="entry name" value="FACIOGENITAL DYSPLASIA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25351">
        <property type="entry name" value="PH_BUD3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="3">
        <location>
            <begin position="249"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="815"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1134"/>
            <end position="1267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1325"/>
            <end position="1344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1378"/>
            <end position="1400"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1544"/>
            <end position="1578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1143"/>
            <end position="1152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1221"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1250"/>
            <end position="1267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1589" mass="176316" checksum="4DD44D7F6E169BC5" modified="2025-10-08" version="1">MVRVTDDIALPSESVTLYHSCDPLLGEHPVLVFHGPSTTANYTHNSSRVQVHVFSAAGFQSFHRLTISPNSPFYTVVDYLPREFQGDEVYRGLAFGLFKYFSELPESVKLYLRNRYANTRLKLPGPPPVLFGEQHAADLAKELVQSNNTVDVVKSLQTALQTQHISNVDLDFVLPPGSIIPLQAEDYEDYTDDEDDILDPSLRQYGGYTPLVRLLGESVFLPTSRLRRAPSKPTSLNRGKAFSKDQKFDLRMKLCELVDTEQRYVKKVNELVNSIAADFRKAAQAKTPESQSPTVEEVDKLFPESLDTILNLNTAFMHELRKVMDDSEEEAQKDMEHTSATMIGSKLGASTRSKDPSGALAVARLFLEWFPKFTESYQNYIRASQNFPQMINSFMEKQSTFKNRVGQAGEQTIRSSLIEPVQRLPRYSLLIDQIVACLPITHPALQPMLRARDIITNICSMDDPLPDKPYVANRLRNMVEAWPESLVPQGRIIMAADFIEIPAPVTTARIGLSDMSGMFLVFADCVVLVKKQTHNITGRDFLRELDKPSAAGLMVSMTNAAGGTAEYDLLFMGWHDLADVRFTESDDGQLVWMTSVKDMKRTHVNELSLDLTPTSRCFRLQETFEGKANRWTEDIAKARVEGRFAEAEREDPRWTLRSIRMPDSNLGLFAAVFQEGADYLVEGRKEPAPIRVVIDHERGTKGAPIGHYGVDIVVNVGAGDLRRLSINAVGLGGKAFHDEVALEDFLPTLSRRIIQLMSSQLNVWNPNLVPALVSYYTKTVKGLNLTGTREKSRSFLATSPVKLLSNIWNGTLSSAPDQVQQSSKHSRTPVSAVFPSQGAPSLQPRELQRSGSQHSIFGSIRGRDRVPLDDTKPENPLVRLEGTFTGYVAALQQRKGNILGRAVMNRGSVDELAVNDLYNRLIEAPFDFEYSSDLGADVILVAFEKFLRIAWTEQMGPIMTMNALDKLQARLNRRVPGDFADFVNYLFGDMAPQNRRAFTSLIKLLADLLDGCGNDSDRGALTLAFAEILVPQDDAANYMNLLDRLVEDCDRIFDESGNIGAGGAQNALLALANANGYLDTINGSGTMRGIKSHSGSLTSNTSSLRRKFGFDTLLRQNSKDSTHSDKSIWRSFSKHGKSATDISQSNSTSSRGSRTRSVDLSNMGQTRARRPLSRDRPPVTGAFEEYSYVSSRPPSSHRMEPPPQLETIGEPVGVYGTAGGTKKKRTKRRSSLSDLRSLMATTSLDDDSETSVVSPPQPIPQITTSQTTSAIKHTMVTIPPERFATIRAHSPSRIPVSPASGVAIHQSIIRPPRMKENIATSDIFQPPSAGGSSKGTTPITASSSPIISDFNVMKEPREREESSKLPQRIQTKGLSNIPTLKPRENLRPNSPTRGAGQRLRLQSPQRLRERLQSEKQAAAEVDASLKSELSKITEDMARVGNSAVGGGRHNTPEFRRLAAAVRNLEEQIPTTIHEVSDRHESLQQDMEMTMKAHEAKVVEIDTLYQKTALENKALYDRFNTELVKIVKAVKGKGREDKEELLGLMTQQGEEVAKLRKDNLKLKRELASLRAAVKGLDIQVPNPNQGQPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN00</accession>
    <name>A0ABR3ZN00_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha</fullName>
            <ecNumber evidence="4">2.5.1.58</ecNumber>
            <ecNumber evidence="3">2.5.1.59</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">CAAX farnesyltransferase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">FTase-alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Ras proteins prenyltransferase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Type I protein geranyl-geranyltransferase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">RAM2</name>
        <name evidence="15" type="ORF">Cpir12675_000457</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein prenyltransferase subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.58" evidence="4"/>
    <dbReference type="EC" id="2.5.1.59" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033844">
        <property type="term" value="F:galactose-6-sulfurylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.120">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002088">
        <property type="entry name" value="Prenyl_trans_a"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129:SF1">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE_GERANYLGERANYLTRANSFERASE TYPE-1 SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01239">
        <property type="entry name" value="PPTA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48439">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51147">
        <property type="entry name" value="PFTA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00040965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1901587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="497" mass="56990" checksum="E1E2ED5440E4D1E3" modified="2025-10-08" version="1">MPPKPKAGAKPSKGPDSTSLVDHQPPATVGERSFHRYHQTNLASKKFDELGITGLDSADLTAWANAKVLREVASGEIFRNARSERDYWKRVQKDGVPFRSVQKGYDWGTDDQGRLISDYSLSEFEDRLKTLEESLRLRRQRTTDQACYAAVYHINATMAGLNESLYGQQKMAFSDDPIWEDVPPIPAEEPEGSLAAIAFPPKYAEATAYLRIVMASNELSERAFRLTAHIISMNPAHYTVWLYRFRILEALKLPFDGEIKWLNEVSLEHLKNYQIWHHRQLLMDKHYPTIADDKAQVNILARSETKFITQMLEADAKNYHVWSYRQWLVRRIGVWNIQELCATQNYIEQDLRNNSAWSHRFFLVFSDPMASSGAAVHATEADPKVLHTIIERELAYAREKIHLAPQNQSPWNYLKGVLVKGGRSIETEKAFVEKFVRNIGEGDEEAVLSTHALDFLAEILVARGEKERAAVCLSRLSEKWDPVRAGYWKLRQQQLAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN92</accession>
    <name>A0ABR3ZN92_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PUM-HD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_000068</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07920">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033712">
        <property type="entry name" value="Pumilio_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537:SF48">
        <property type="entry name" value="MEIOTIC COILED-COIL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537">
        <property type="entry name" value="RNA BINDING PROTEIN PUMILIO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00806">
        <property type="entry name" value="PUF"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PUM-HD" evidence="5">
        <location>
            <begin position="407"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="469"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="505"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="122"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="337"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="757"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="8"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="123"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="342"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="363"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="776"/>
            <end position="787"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="787" mass="85835" checksum="86C4295A34950988" modified="2025-10-08" version="1">MFAYNAQGRNSSSGSRTLSGSSPRGPSGSRSPVSRHMNCISRLQSLSLNDSRGTAVKQTPSIPVALPHPHRIDTRVNDGLRKQADKHMNSNESSEKGVDLLLARLSEQEDFIMKQHEQFNNINSENSGGLTNTSGNTTSDVSPSNSGKGILTEGHHNQALAPITNTKPTSQDEVAQLRIQLAEAQAAISSMHHQQNYQPVPVTMPPISIDQISASVNNGIGNGMVGNMGVNFAAKPPTSSVSYIWNPLNSGTNGSPELIHGYPTRNDPGDIWAPHPLYDSSIDSGPQPLDGNMGWPTARAFHEYIRGNSAATFSAPVDQVPPSSSNERLTPELDMYPRLGRRNGGSGTGSGGSGGVNGRFESRQSPAPLNNGSMSTTYDQFVSGSSNAYGDGPNAAFNPETGAQSSFPSYIPPGATDLNPFIGGSTPQSRGDKFIVDKIIQQNDQQASIFLQQKLKVGTTSQKYDIVEAIIEQAYSLMVNRFGNFLVQRCFEHGTPEQVVKIAQAIRGRTLSLSMDPFGCHVVQKAFDCVPEEYKAMMVRELLCRIPETVIHRYACHVWQKLFELRWTEAPPQIMSYVNDALHGMWHEVALGETGSLVVQNIFENCLEEDKRPCIEEVLGNIDIVAHGQFGNWCIQHICEHGSESDKARAIDHVIRCAAEYSTDQFASKVVEKCLKIGGPDFISRYLERVCEGRPDRPRIPLIDIAGDQYGNYLIQYILLNTTQQFRDAVAIHIRKHMVSLRGSKFGSRVGMICTNPASATRPGPPMGPSIHSNRMGGGRYSGAGYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNE5</accession>
    <name>A0ABR3ZNE5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA repair protein XRCC4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000076</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42067:SF1">
        <property type="entry name" value="MITOTIC APPARATUS PROTEIN P62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42067">
        <property type="entry name" value="YALI0C15378P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58022">
        <property type="entry name" value="XRCC4, C-terminal oligomerization domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="207"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="209"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="231"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="262"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="331"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="356"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="403" mass="44108" checksum="3EB49BA4C96F7BDB" modified="2025-10-08" version="1">MAPLEYILRFAVADDEDSSFVLVQAIQTGDSLLDLKLVGTEVQSAHISGLKSKKASVLDTEWEDILKDVFTQEPVKDVQVFAQVNSESSIHLIIRRSIQGYSSRLGTIVLAHSPDEELELMEWCSKASQASASTKEALASRRQQIAELEKTIGHLKNQLSELMDARTRDEGVLLRKFRDLLNEKKLKIRQQQLIIAESAAAATYIATKTPEKTEKPKDVADASGDEETTRRPTRSMRGRGRARGRGARALQQSRPQKRKAPGSRGSQSSSDSESDSGFERMDVGRAAVAKPEHSSEQDTIEGEAGDVTASNTEDEDDNIIGNSEPPRQRATRSNIAQTGKDNAITASQAAKGAACDSDEEDEEEVAEPPPARVLPFSTRRKKPLTETLPPVAGEETTADEDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNV5</accession>
    <name>A0ABR3ZNV5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amine oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000038</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43734:SF4">
        <property type="entry name" value="AMINE OXIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43734">
        <property type="entry name" value="PHYTOENE DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="1">
        <location>
            <begin position="16"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="513" mass="57257" checksum="0DF802BC0AD60A8B" modified="2025-10-08" version="1">MADTKVDVLIIGAGPTGLGAAKRLNQIDGPSWLIIDSADKAGGLAGTDATPEGFLFDVGGHVIFSHYKYFDDCLDEALPKEEDWYNHQRISYVRYKGQWVPYPFQNNISMLPVEDQAICIDGLIEAALEHRVSNTKPKDFDEWIVRLMGTGIADIFMRPYNYKVWAVPTTKMQCAWLGERVAAPDLKKVVRNVIEGKVAGNWGPNATFRFPARDGTGGIWTAVANTIPEDKKRFGQKNEVIKVDPAAHKVTLKDGSTITYGKLISTMSADHLIKQIGDSELEEASKNLFYSSTHVIGVGIRGARPDRIGDKCWLYFPEDNCPFYRATIFSNYSPYNQPQKDDKLPTLRLADGSKPASTDAQTGPYWSIMLEVSESSMKPVDHKTILEECIRGLINTEMIETSDEIVSTYHRCFDHGYPTPSLEREDGLKVILPKLQDMDIYSRGRFGSWRYEVGNQDHSFMLGVEAADHITSGAVELTLNYPDFINSRQNSERRLGPLGVSSSSTLAVNSHKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPH9</accession>
    <name>A0ABR3ZPH9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_000163</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1902057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="259" mass="28643" checksum="529A9A2185A37C73" modified="2025-10-08" version="1">MIDLDLLGDTGSQVLLEVVETSLDEVILALRETVLVQDEATVPSSYLPKKTGVPGLDSLAMKNFRETQTSPISVSGRSLPFIHALLDHLVSPPQSKTVALIDLECGFDPTRLASSRSNLSHIHVFRMPPATADSTASSIAEMVREAVARVQQWMVYGSHQSAGREWWGTIILGAPGGQVWTCWRGWLCVDTEDIPGFATGMSIREAMAERERREQAVDSMNWVASCPWGRFDFRGRLVQENEELQRHHKLEDDAASGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YBH4</accession>
    <name>A0ABR3YBH4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RAS2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ras2</name>
        <name evidence="4" type="ORF">Cpir12675_006986</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000490">
        <property type="protein sequence ID" value="KAL1885345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="190"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="191"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1885345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="235" mass="26581" checksum="81FA771858D7EA6D" modified="2025-10-08" version="1">MAGRMVLYKLVVLGDGGVGKTALTIQLCLQHFVETYDPTIEDSYRKQVVIDNQPCMLEVLDTAGQEEYTALRDQWIRDGEGFVLVYSISSRSSFTRIRKFHHQIMRVKESFSTSPSYPASPVAATSTQMPVSVMLVGNKSDRVTEREVSTQEGHALARELRCDFVEASAKNCVNVEKAFYDVVRKLRDQRQQISRPPQLVTGRQNTAKSSRQQSNGSAPDGNNRYYRQKHRCVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFM4</accession>
    <name>A0ABR3YFM4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Retrotransposon gag domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006696</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000355">
        <property type="protein sequence ID" value="KAL1887091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005162">
        <property type="entry name" value="Retrotrans_gag_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03732">
        <property type="entry name" value="Retrotrans_gag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Retrotransposon gag" evidence="1">
        <location>
            <begin position="74"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="165" mass="18629" checksum="25621337F13607D3" modified="2025-10-08" version="1">MDIDVTPVYTPAPPRSQGFSQFDGDKGIYRIWKRQMSAMLLLHGYADMTRVVVAIAAGELGRLAEKVGSTVAEVWKVLDGHFEDPIFRARASERLENLEQGNKTQDRYIFEYRDQLQQAGGDSYPKDVKIRGLMRGLNDALYERMVTIPMSLTLTSQIESLRGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFT5</accession>
    <name>A0ABR3YFT5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Exosome catalytic subunit dis3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">DIS3</name>
        <name evidence="12" type="ORF">Cpir12675_006663</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the RNR ribonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000345">
        <property type="protein sequence ID" value="KAL1887166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09862">
        <property type="entry name" value="PIN_Rrp44-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041505">
        <property type="entry name" value="Dis3_CSD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022966">
        <property type="entry name" value="RNase_II/R_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050180">
        <property type="entry name" value="RNR_Ribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033771">
        <property type="entry name" value="Rrp44_CSD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033770">
        <property type="entry name" value="RRP44_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355:SF35">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RRP44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355">
        <property type="entry name" value="RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17849">
        <property type="entry name" value="OB_Dis3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13638">
        <property type="entry name" value="PIN_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17216">
        <property type="entry name" value="Rrp44_CSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17215">
        <property type="entry name" value="Rrp44_S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01175">
        <property type="entry name" value="RIBONUCLEASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6" id="KW-0271">Exosome</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="887"/>
            <end position="981"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1887166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="983" mass="110391" checksum="66594289403D1FD2" modified="2025-10-08" version="1">MTSLKRAGDVDPLAANISSKIYVRSTRSGKVQKIVREVYLRQDIPCSSKLCTQCFDAAPRDARNHVQPFILAGKPLGSRDFPNGRYILPDTNILLNAMDVFEQSNAFCDVIILQTVLEELKNRSLPLYNRLIGLVNSEDKRFYVFFNDFRLETYIVRGNDESINDRNDRAVRKAAKWYNEHLAKCRGTIPTTILLTNDKDCLAKSKAEKIPCMALSEYLSGVEDGERLMDLIAESQAQSGGFSKVVKMLYPEYFTMSKMMTGVKGGVIHQGIFNVSQYNYLEGSIKVPAFPKPLIILGRESINRAIDGDVVVVEVLPKEQWKTPTTTIVEEDSITKDENADVEEDVNIVSAKEKKALQDEARKSQAKGAESHAQPTARVVGVVKRNWRQYVGHVDPTSASRDSGQGRKQNSVFLLPMDKRIPKIKLRTRQVSELLGKRLLVTIDGWSRDSRHPTGHLVRNLGEMETKAAETEALLLEWDVQYRPFPKTVLDCLPTEGHDWRVPADTGDPGWRDRKDLRDLLICSIDPVGCQDIDDALHARPLPNGNFEVGVHIADVSHFVKPGNAMDSEASIRGTTVYLVDKRIDMLPPLLGTDLCSLKPYVERYAFSTLWEMTPDAEIVNAHFTKSVIKSREAFSYEQAQLRIDDVSMQDELTAGMRTLLAMSKKLKQKRYDAGALSLSSPEVKVQMESETSDPIDVKTKQLLDTNSLVEEFMLLANISVAARIYDAFPQTAMLRRHGAPPRTNFDDLSTQLRVKKGMELRVDSSKALAESLDSCVDPANPFFNTLVRILATRCMMSAEYFCAGTQAYPEFRHYGLASEIYTHFTSPIRRYADLVAHRQLAAAIEYEPVHPSLRSRGKLEAVCKNINVRHRNAQMAGRASIAYYVGQALKGRAVDEDGYIMRIFSNGFVVFVPRFGIEGLVRLRDLAEPEPEADFDADNYTLTVKGSQQLKVELFQVVKVRVSDSKDEATGKRGVKLELLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGE8</accession>
    <name>A0ABR3YGE8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006566</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000325">
        <property type="protein sequence ID" value="KAL1887386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF103">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="370" mass="38692" checksum="A126573380B11547" modified="2025-10-08" version="1">MASRIASSNLARFATRMVRPAQNNSASLGARAFSTGKINSLKVTGAKNEIVREKEVPVSVYATDGKGSNSASSDHFTIPVKATGAPTGTPAPPVADENVAPLTQAQYDSLPKTMKSMSLMGKVVIVTGGARGLGNSMARACAEAGARSIILFDANQELGDQAAEELHSKTGLPVTFFKVDVRDGAAINAAVDSVVQNFGAPDVLINSAGIADSNIKAETYDPAMFRRLIDINLNGSFLMSQSVGRAMMAAGKPGSIVLVASMSGSIVNYPQEQCCYNASKAGVVQLGRSLAAEWAKHDIRVNCISPGYMDTALNNVPALDAQKKIWKSLTPQARLGAVDDLNGLCVFLASDSSAFMTGSNVLIDGGYTCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGK0</accession>
    <name>A0ABR3YGK0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Jacalin-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006793</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000377">
        <property type="protein sequence ID" value="KAL1886972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.100.10.30">
        <property type="entry name" value="Jacalin-like lectin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001229">
        <property type="entry name" value="Jacalin-like_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036404">
        <property type="entry name" value="Jacalin-like_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038772">
        <property type="entry name" value="Sph/SMPD2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320:SF1">
        <property type="entry name" value="SPHINGOMYELINASE DDB_G0288017"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320">
        <property type="entry name" value="SPHINGOMYELINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01419">
        <property type="entry name" value="Jacalin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00915">
        <property type="entry name" value="Jacalin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51101">
        <property type="entry name" value="Mannose-binding lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51752">
        <property type="entry name" value="JACALIN_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045280801" description="Jacalin-type lectin domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="Jacalin-type lectin" evidence="2">
        <location>
            <begin position="294"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1886972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="438" mass="48054" checksum="9DB859A02EB29012" modified="2025-10-08" version="1">MKYNTIATIAALSTPSLVHAAAGTINVLTMNVAGLDNTLQGGNVPGDKSSNSKRIGSYFAEYGYDVINIQSDFDHHNSIYETDNHNHRTNTLGSFGKGDGLNTLSKLPFIDFRRIKWDKCSNNEGRDCDTRKGFTFMRMRVSEGVYIDMYNLQTDAGMTGKDIDARAANLAQVSEYINKWSIGNAVVVFGDTNSIYSRTSDSIGIFQEQNGMKDAWYTLVRKEDGSSDTTCHNPSDTLLCELGDKVISRGSELLTLDATTFEYVGKKFLQPNGNVLSDRDPVQVGLAWCQSETLRQSDLFGAPHGQVWFNDATTIASKGNRPKAAVIGFSGGRRLDKVAVTLSDETLFEHGGKGGKWKKITLAVDEFWTKVDLCQGMKEGKTRIFYIKATTSKNQILEVGKSSDTCTTYVAPSGFQILGFVGQSGDEIDQLGVIYGLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGS7</accession>
    <name>A0ABR3YGS7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcription factor TFIIIC triple barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006641</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000339">
        <property type="protein sequence ID" value="KAL1887225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.4370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019481">
        <property type="entry name" value="TFIIIC_triple_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10419">
        <property type="entry name" value="TFIIIC_sub6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription factor TFIIIC triple barrel" evidence="2">
        <location>
            <begin position="42"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="143"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="471"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="526" mass="57332" checksum="DF0B79B0644ADD93" modified="2025-10-08" version="1">MQPIKTHEMLAGGFTRPSPKPYKTEIPTYDDEDEWEYEYSTTETETYYLTLDLSIPEFTTRDSRNIVQAGRGGYLSSWIGDPEKENGNSSENKARYRFAADDIDEEDDQELPEREDQDPDDIDTSSIDPTLKAVDATAASINAATTDPTTGPADASSHSQTDRSNAINTASFEAPRRNDTDADAGEVQILELHSKTPIIAYRGRIFEGEWAENSGTEMIFAAQGGSECDDTGGSESLPRIDTLPGGIDLLAASSARILTTERKIQPRLDTNLDEVKSQFGIRVVAGRDLNGDRRKQAAFLENLMAVKRIKGEADSVPVFARPPINKNFRDDRDPDWKPRRRKLRPVEAIPRMGRTVVMGSAVGDSKGKGKAVEPQIGEDITGQEAGAEDITEMEAEAQAAEPAQSVVFQPPWQPRGNSGPVPFFSTPQFRPRRKKQQLPNADEPKKQPLSKTSLPVSRSARTALLSEDHGVSVSGVVALGTGAGTGTKQTKGLASGSKDSETAKEDEDGDREAEQNLDVDQDMAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH01</accession>
    <name>A0ABR3YH01_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EKC/KEOPS complex subunit CGI121</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">EKC/KEOPS complex subunit cgi121</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_006603</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. CGI121 acts as an allosteric effector that regulates the t(6)A activity of the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators. CGI121 is not required for tRNA modification.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the CGI121/TPRKB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000332">
        <property type="protein sequence ID" value="KAL1887300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2380.10">
        <property type="entry name" value="CGI121/TPRKB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013926">
        <property type="entry name" value="CGI121/TPRKB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036504">
        <property type="entry name" value="CGI121/TPRKB_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15840">
        <property type="entry name" value="CGI-121 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15840:SF10">
        <property type="entry name" value="EKC_KEOPS COMPLEX SUBUNIT TPRKB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08617">
        <property type="entry name" value="CGI-121"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143870">
        <property type="entry name" value="PF0523-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1887300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="191" mass="20962" checksum="4E691CCA2A840AA1" modified="2025-10-08" version="1">MTLPLETIALEHLPATHTLHMVLFQDVKNAEFLHKQLLARNAEFEYALVDAGIATSRHQIMAAVYKAVSSDLNGTLRTPNVHSEIVNSLSPNNNISESYSRFGISAKSSNVVVCKLAPADEAVAIWSHLSTNVEGTPLKITDENLATVTDWQKVNKYYKLNGLQWLAKLAEDQRKVQAKALVIGSIAVKGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH21</accession>
    <name>A0ABR3YH21_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DRAP deaminase</fullName>
            <ecNumber evidence="4">5.4.99.28</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RIB2_2</name>
        <name evidence="4" type="ORF">Cpir12675_006712</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.28" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000358">
        <property type="protein sequence ID" value="KAL1887066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160151">
        <property type="term" value="F:tRNA pseudouridine(32) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02557">
        <property type="entry name" value="PseudoU_synth_ScRIB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluA-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050188">
        <property type="entry name" value="RluA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600">
        <property type="entry name" value="MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600:SF40">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE RPUSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="3">
        <location>
            <begin position="217"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="32"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="546" mass="60541" checksum="2FD435AA73A79F1F" modified="2025-10-08" version="1">MASPSILPETPLEIAPNPVFALSEDGESLAKAGLQSNQGAKTEATESATSASGRENTASIDLTVSNGSTNIEARVIDTGNERVIVKAPRGKQKGHKHMENEKAKNPNITGTDDIWPRPYFCEDGLRRVKPYFFTYNTYCKQRWRKRELLDIFVSEFRDRPPAYYKSAIEKGLVQVNGSQVPTTYLVQNGDLISHTIHRHEPPVAAESIKVVHEDDAMIVIVKPAGVPVHPAGRYLYNSVVEILKSDRNDPNFFPRPCHRLDRLTSGIMFFAKTQKAAEALGVQISARTVRKEYIARVIGKFPDGEIVCDQPILQISPKLGLNRVRATGKVARTVFKRLAYYGPGECNSDSPSVKKPVAGDAGIDPDVQNLPWMRKQGYSIVRCLPVTGRTHQIRVHLQFQGHPIENDPIYANQKVWGLDLGSGDADGSKQTDDDIMERLQRMGREDAADAVAYHDEMMENYEKRRAEKLSGDVCDQCGTELFTDPGDQELSVWLHSLRYEDAGGAWGYTTPLPKWALPPAGFTGPTEVGSLQVLLDAMKGMDPIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHW5</accession>
    <name>A0ABR3YHW5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DJ-1/PfpI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_006366</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000289">
        <property type="protein sequence ID" value="KAL1887920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052158">
        <property type="entry name" value="INH-QAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130">
        <property type="entry name" value="ARAC-FAMILY TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130:SF3">
        <property type="entry name" value="HTH-TYPE TRANSCRIPTIONAL REGULATOR RV1931C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="DJ-1/PfpI" evidence="3">
        <location>
            <begin position="16"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="291" mass="31587" checksum="E1D457511F5CFA92" modified="2025-10-08" version="1">MSAHKSSAVADEPIEILFALQSGFDLLDFSGAYEVFTEALHDQDDPNSKAFDCTIVSAEPQAVSKQGAHVSAQINYKEAYQRLADFDVLVVVGGEVDNVLIAKAEPMPLLRAYAELQKQDTSRERTVLAICTGAMFLAAQGLLSGLAATMHPDHMTKFEHLCSYAAVCNNVERTEVMDDERYVVNNLRFDIGDEDENPYIRLKSDAGRRGSHGRKGSMSFKGSNSRRESIVRRAAMRLGGLRVITTGGMSAGVDASLYLVSALVDDSAAETTASAISWNWQKGVVVDGLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI57</accession>
    <name>A0ABR3YI57_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_006513</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000312">
        <property type="protein sequence ID" value="KAL1887527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF7">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE_REDUCTASE (AFU_ORTHOLOGUE AFUA_2G00830)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="266"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="286" mass="30578" checksum="043A9BC46563FED2" modified="2025-10-08" version="1">MPAAAVFRAGSTGLITGAASGIGLALARFCAAQGMSLVLADKNIAPLSSFAAEYPASTIHAVTCDVSLPASWTELCESTKTVFGSDRGIELLALNAATCGSRENLWADSGAFRHTFNTNVFGVVHGIETFLPLVRKAASTGHRPTAIVITGSKQGITNPPGNPAYNASKAAVKSIAEQLSFDLQNEPTGVHLLVPGWTFTGMTGANVSTEKPPGAWLPEQVIEYLDRKMAESKFYIICPDNEVDETTDKKRMTWAMGDIINDRQPLSRWREDTKAEAAKSNEKMTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI60</accession>
    <name>A0ABR3YI60_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatidate cytidylyltransferase, mitochondrial</fullName>
            <ecNumber evidence="6">2.7.7.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">CDP-diacylglycerol synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="primary">TAM41</name>
        <name evidence="20" type="ORF">Cpir12675_006515</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TAM41 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.41" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000313">
        <property type="protein sequence ID" value="KAL1887518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015222">
        <property type="entry name" value="Tam41"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13619">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13619:SF0">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09139">
        <property type="entry name" value="Tam41_Mmp37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="17" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="498"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="504"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="516"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00029893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAL1887518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="527" mass="59335" checksum="C0F8444EE85D2B9A" modified="2025-10-08" version="1">MALSRRASSYHYARLPNPASMRICIARPRIQSWAVSREIRCTRSYGSDPTSRPTPSNGVDLEKSLQYAVSGAGATKMKAVDWEDYKYSDVRKFDDLPARGFGWNQHMVINAELREALTMMLRQFKAPIMYCFAYGSGVFAQSSSVSNISDDEFRAVHPKAPEALKQTQKSNPKMIDFIFGVTHPQHWHSLNMKQHPEHYSGLAKFGSGLVTSVQENLGAGVYFNPYVVVNGMLIKYGITSISNLCKDLSTWENMYLAGRLHKPVKILRDNASVRIANQQNLMAAVRASLLLLPENFTEQELFNTIAGLSYLGDPRMVLPTENKGKVKNIVSNNLVNFRRLYLPLIHNLPNIDYKAGSSSTSGLEVSDWAWLESTENRSLSQDMDPVRRANMVRRLPSSFRGRLYFQYQKQFGMTRAEFNQLMEDSSDNTPAGIKRPQGSDFDMRIAQDNPANLNRTVRDTIVQTIKWPSTTQSAKGLLTAGFARTIRYMSEKMARYREGKAQKNGATATIATDSRSLGERSSSNEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJH0</accession>
    <name>A0ABR3YJH0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_006341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000284">
        <property type="protein sequence ID" value="KAL1888007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1888007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="92" mass="10327" checksum="F040C69116DD216D" modified="2025-10-08" version="1">MASDRSARPGAPSEGPLFPPTFLCCQATSLFRPLSSDHINWTVWCFHNSLFGRVDLDVHQSLSNYAARDPRFPSYSINACNRPKFQAPEINV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJX4</accession>
    <name>A0ABR3YJX4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Wax synthase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_006308</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the wax synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000279">
        <property type="protein sequence ID" value="KAL1888086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044851">
        <property type="entry name" value="Wax_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032805">
        <property type="entry name" value="Wax_synthase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595">
        <property type="entry name" value="LONG-CHAIN-ALCOHOL O-FATTY-ACYLTRANSFERASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595:SF57">
        <property type="entry name" value="OS04G0481900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13813">
        <property type="entry name" value="MBOAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="86"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Wax synthase" evidence="9">
        <location>
            <begin position="125"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1888086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="311" mass="35077" checksum="AC8C5A8EEEB51555" modified="2025-10-08" version="1">MEIIDISTIPLVSRSGHTRCKTRADFFRRTLYAAIPGYLMLDLLTILVEMDPFFIAGPRGMYPPFEYPPAHLSWIPAMLLPAYRALFFLTCILAALHVVFHHLEVVQFFVFSYLFPMRAEPWMYSSIFGPVSSVWETGLSGLWGVFWHQTFRAPFMAPVRYIWGHGKGRFPGKKAALLASAFIGSGLMHAGASFTSTPSTDYFRPLLFFLAQGVGIGLQKTLCKALRPLGLPRSLRRIGNLLFVMAWLYGSSPLLGDDFATGGVWLLEPSPYSVLRAMGYGYPGESPWRWDRDHMGSLYVGKHWWEIGYGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKU7</accession>
    <name>A0ABR3YKU7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">tRNA methyltransferase ppm2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PPM2_2</name>
        <name evidence="2" type="ORF">Cpir12675_006158</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000260">
        <property type="protein sequence ID" value="KAL1888463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46529">
        <property type="entry name" value="TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46529:SF1">
        <property type="entry name" value="TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="108" mass="12406" checksum="32788D7396E95318" modified="2025-10-08" version="1" fragment="single">MPPKNAKDSGTKASLTASSAAEKKKAFLDELIMGTNSSSITSKRSVEKLYYHEEKHFFRFFVPRFQRRSPLVNRGYWFRLRAIDVSVREFLRRDCGGKRMVVVNLGCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL62</accession>
    <name>A0ABR3YL62_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006113</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000255">
        <property type="protein sequence ID" value="KAL1888568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="106" mass="11935" checksum="258B369DD33287A0" modified="2025-10-08" version="1" fragment="single">MASTKTYEKYEEYKRDLLVLDSSLGYSSREDEPTQTSKAPSQKGRPYTPTRNGNSSGDRRRARWVSAAEQEKRRKEGRCFRCGMSSHSIHNCPHAGPIPPGSTSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLK9</accession>
    <name>A0ABR3YLK9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005864</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000224">
        <property type="protein sequence ID" value="KAL1889236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="247" mass="27799" checksum="04CB47AF445AC2C6" modified="2025-10-08" version="1">MENETPCVLKETYPSKDAVEKSLKRDLKDHRKGDNQAEKLMNLCQHLFNWTWTCAMQFQFPPILLLVYYAVTAVCFALLWASLVILNDEMCIGLSPIFIYEVLMACTPVDLKSVEMLIQLAVKLANMQLSEGGLEVSLDGMLQKLFRISGTNPENAIANGSIPNHFADLGIYFAGQVHRVLCDNPQQMPLIIRYLEGIAAVQNSNDIPSQTYNPQDESHASMPSEVLPLDFQDMSYDELMLELFDTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM03</accession>
    <name>A0ABR3YM03_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">COP9 signalosome complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_005883</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CSN4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000226">
        <property type="protein sequence ID" value="KAL1889217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054559">
        <property type="entry name" value="PSMD12-CSN4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040134">
        <property type="entry name" value="PSMD12/CSN4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855:SF2">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22241">
        <property type="entry name" value="PSMD12-CSN4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="PCI" evidence="8">
        <location>
            <begin position="201"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1889217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="433" mass="47733" checksum="65B83441D19D615B" modified="2025-10-08" version="1">MSVTPQVAKSIANIESLTSDKASLYQNLIQTLPSISSPENLLVDYNAITDSFSHAQMGGIVATRSVIQTFIDKLRSTNQPDLSISVGQHLLDALDTLAAASSVIEQVAEIRELIACAHEANEDFALAAKTLTEIPVDTPQRKLAPGPLAAVWVRIVRNYLEVDDTVAADIYLGKLIHIMHAVDDPELLLHYSLSSARVLDATRRFPDAAARYMEVSVSPIIAEEERLHTLSMAIKCGILAPAGPERTSLLGRLYRDERSKMLPEHAMLEKMYLQRFISPSEIESFAKTLQPHQLALTADGSTVLARAVVEHNLLGASRLYANISFPALGELLHLTPERAETTTARMIEQGRLVGSINQLDSLVVFEKAESATFKKENENAVLSHKDKGRATVRNKKHIKQWDSNIQGLSEEIENITDSLQQKFPEFVASNLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM86</accession>
    <name>A0ABR3YM86_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein saf4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">saf4</name>
        <name evidence="3" type="ORF">Cpir12675_005784</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CWC16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000216">
        <property type="protein sequence ID" value="KAL1889449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007590">
        <property type="entry name" value="Saf4/Yju2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111">
        <property type="entry name" value="SPLICING FACTOR YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111:SF2">
        <property type="entry name" value="SPLICING FACTOR YJU2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04502">
        <property type="entry name" value="Saf4_Yju2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="317"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="379" mass="41330" checksum="D6906D9A4446BE5E" modified="2025-10-08" version="1">MQGFNMGRYVPPDAEGVSSGNQIHRKHPLGARGRNAASTGAIVVRFEMPFNVWCANCPRETLIGQGVRFNAEKRKVGAYYSSSIWAFRMRHTDCGGTLEIRTDPQNTAYVVVEGGRRQDRGDLNGPAPDALNLVHESDDVAAAEATSQTREELRQTAFGRLEKTIVDRGEVARATERLDELQDAAERAWDDPYMRNQQLRSVFRAGRKEREREAMEAQDLKDRLSLGAGIELLAGSREDELYASLVDFGYDDADAARIVEREAMAKPMFGGGKAEAETEAGRRKGRGVLKAEALATARKSAFVSQVVGNTRLSQDPFLAKRTDDPQRSSGIAGIKRKRVGENGEPSKPGGEQAGAGDAAESRIKAPKAALVNYDSSGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMA8</accession>
    <name>A0ABR3YMA8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_005961</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000235">
        <property type="protein sequence ID" value="KAL1888988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15859">
        <property type="entry name" value="SNARE_SYN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="4">
        <location>
            <begin position="171"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="97"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="209"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="106"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1888988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="261" mass="28572" checksum="3B4767A8CB7877A1" modified="2025-10-08" version="1">MSTTGHLFILADHIKLALLERQRASSALAAGTSLDAEADSQDGHIARSLEQLNEGIAALRAEEDRLRIAGSEDAANDIDDSLITLSKQLDSLTSQFHRFTAPDPPSASSSPSAPDSQGVRFRDSDVTAGDGAADVEAQQLFGTHYTDATDSAGYRDEADDMLNEQIHTFHGRIMDEQDAHLDRLGESISRQRELSMRIGDELDAHVGMLEDTEAVVDRHQSRLDRARRSLNRIAEDESDSRGMMTIVVLIIILILLIAILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMH6</accession>
    <name>A0ABR3YMH6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_005915</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000230">
        <property type="protein sequence ID" value="KAL1889107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF18">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="208"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="399"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="425"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="470"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="506"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="7">
        <location>
            <begin position="71"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="568" mass="61784" checksum="1270DC160236C104" modified="2025-10-08" version="1">MALPVPSDYGAAKDHHLKDNPSYAADVESGSESKSPAKGIALGLDSTEDHTGDMVMSIENRRLKRGLDQRHLSMLGIAGAIGTGLFLGLGGAIQTAGPLGSLLGYITVGLVVCAVQFAMGEVTAFLPITGSFVRHAEFLVDPSLGFAVGWILVYGNILSIPSEITAICVLFQFWTDISPAIFIVVFIVLTVVVGISFIRIFGEIEFGFALLKIVLVIFLIILGLIIDLGGVPGTSRIGFRYWKDPGPFVEYIASGSWGNFLGYWSVMTGAVFSFAGVESLAVAAAETNNPRRAIPRACKNVFIRIVLFYVLAVVVVGMLVASNDDRLNNESGTAAQSPFVIAASAAGLPAIPSIVNAVVITSAFSASNQALLTGTRVLFSLALKGQAPKVFLHTNRWGVPWVCVLVYAAFMSLSFMSLSNSAMTVFWWFVNLTAAGVLVSWSTILLNHIRLRQALKVQNISLSRLPWYNRWSYVTSIVGLIMCQVILWTSGFVVFTKGNWNTSNFVSSYLVIPILFVLYFGWKFWNKTSLVDLKTVPLQRILEHIAETPEEPDIPKSGPIRLISWLWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMI0</accession>
    <name>A0ABR3YMI0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Leptomycin B resistance protein pmd1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_006119</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000255">
        <property type="protein sequence ID" value="KAL1888574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF27">
        <property type="entry name" value="ATP-DEPENDENT TRANSLOCASE ABCB1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="151"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="252"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="365"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="759"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="808"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="879"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="911"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="993"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1025"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="97"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="429"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="763"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1089"/>
            <end position="1327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1888574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1334" mass="144973" checksum="7764790E828CC974" modified="2025-10-08" version="1">MEKQDPEKLGAAASGPDAGSDHGSSVTPRAAEAATSLAKADTVANVPASVTPDVDPYAHLEPGEASILRRQIDTVNVSATIKTLYRYASRNDLIIVAAAMLASMASGAALPLMTVLFGSLQGTFSDYFAGLDSPSPDAMTYDEFIDEMSKFVLYFVYLGVGEFICSYISTVGFIYTGEHISAKIREKYLESCMRQNIGYFDKLGSGEVTTRITADTNLIQEGISEKVGLTLTALATFFSAFIIGFIKYWKLTLILTSTVVALVINMAIGSRFIVRFSKISLTSYAQGGTVADEVLSSIRNAIAFSTQDRLAKKYDRHLTHAERFGWMVKATMAVMIAGMMLVLYLNYALSFWQGSKFIVDGTVPLSDVLTIMMAVMIGAFNIGNVTPNIQSFTTAIAAASKIFSTIDRVSPLDSASDEGIRLDKVEGTITLENVKHIYPSRPEVTVMDGISLTIPAGKTTALVGASGSGKSTIVGLVERFYDPVHGRVFLDGHDISTLNLRWLRQQMALVQQEPTLFGTTIFENIRYGLVGTQWENAEADKQRELVEAAAKRANAHDFIMSLPEKYETSVGDRGFLMSGGQKQRIAISRAIVSDPKILLLDEATSALDTKSEGVVQAALEAASSGRTTITIAHRLSTIRDAHNIVVMAAGRIVEQGTHDDLLELRGAYYKLVSAQEISRSGAQNSEEEEKELAEIDEQVTRELSRKETSAAAPESLKMAKSATGMSFAGSFTGSQKGVEHNYSLWTLIKLIASFNRDEWPLMVGGLIFSMICGGGNPTMAVLFSKQITTLSRTITPETKDDIKDKSDFFSGMFVMLAGVMWISFSGQGILFAKCSERLVHRVRNKAFRAMLRQDVAFFDRDENTSGALTSFLSTETTHVAGLSGATLGTLLMVTTTLVSALTLALAIGWKLSLVCSATIPLLIACGFLRFHMLAHFQRRSKAAYTVSASYASEAIGAIRTVAALTREGDVLRQYHESLAEQQRVSLRSVLRSSLLFASSQSLVFLCFALGFWYGGTLIAKQEYDMFQFFVCFMAIIFGAQSAGSVFSFAPDMGKAHQAAGELKTLFDRVPKIDSLSTDGESLPHVEGTIEFRDVHFRYPTRLEQPVLRGLNMTVAPGQYVALVGASGCGKSTTIALLERFYDPLSGGVFIDGHDISKLNVTQYRSHIALVSQEPTLYQGTIRDNIALGSEGPDLTDEDIASACKKANIYDFIMSLPEGFSTNVGNKGTLLSGGQKQRVAIARALVRNPKILLLDEATSALDSESEHIVQAALDKAAKGRTTIAVAHRLSTIQKADVIFVFDQGRVIERGTHDELMKLGGRYAELVNLQSLEKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YML1</accession>
    <name>A0ABR3YML1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome c oxidase assembly protein cox19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">COX19</name>
        <name evidence="7" type="ORF">Cpir12675_005931</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Required for the assembly of mitochondrial cytochrome c oxidase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the COX19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000232">
        <property type="protein sequence ID" value="KAL1889046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051383">
        <property type="entry name" value="COX19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21107">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21107:SF2">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00037279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="86" mass="9057" checksum="C36B9E7A256F404D" modified="2025-10-08" version="1">MTKYLGCLKNVRGVNDEACRELAKGYLTCRMDNNLMARDDFKNLGFKGGESKTMSCPIPVATAAAEATTATPSNHANVAGGQGSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMV3</accession>
    <name>A0ABR3YMV3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005758</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000214">
        <property type="protein sequence ID" value="KAL1889518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="390" mass="40948" checksum="49B11FE3A5E8C15F" modified="2025-10-08" version="1">MSPMQKIHEDSLYGQPTLYNSGHRAVPEVSRQRVKHSRRMFWIRLTALLAAVVVAVAAAIAIMAVTINWDNKVTNSEGARSVRRADPAPLGLKIGSLALVVTPFLTSSIIAFFASPGVSAIPVPEPSAFTSAPFSNITMNTIALPGTSATTLSSSFLTAWNPPIATGTAYSRIPLSSGTRPHYSYFTAPSVPPYGNSSDYHYYPTGSTETGTGSSSWSLTSTDYETASDVECTESVTVTVTVTASDDSYDSVPSYTDFATPTAFTSDDDFTEIETTTVTPTFTTFQTTTVDSVQVITVLDTVSGTLTPVTTLTVVDGQPPFTADNSTATGQGTAISTGFPTASGAKPISTDDGPNGEFSGRNQLNVAGRLGRSTATMLASAAIAAFVAMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMY0</accession>
    <name>A0ABR3YMY0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_005741</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000212">
        <property type="protein sequence ID" value="KAL1889548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF22">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G11480)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="16"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="46"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="76"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="106"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="127"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="196"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="315"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="140"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="151"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="339"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="350"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="425" mass="47666" checksum="AC8CBEFCDF456019" modified="2025-10-08" version="1">MELMELVENEPTARPFQCDWTNCNKFFNRKSDLQRHYRIHTNERPYSCMTSGCGKSFIQRSALTVHIRTHTGEKPHQCQHVGCGKRFSDSSSLARHRRIHTGKRPYKCSHEGCLKSFCRKTTMVKHQRRSHQRGLLPNEMLDDCTSESDSGESPSTPKNSAIQWPATGLMPNAMSSQMIHRAQPYGSFGSQMPTYNITSAYTPPGAPQQPREYDGTPSQPGAAMHMVHRSTSMPYYVTEQANPGVATMNATMPQYQIPRGHPVDRLDIPAYPQASVMSSPTGYMSAPVRSAGPHDPGFYGHPAQATYTLHGASPVDHQAHHQPAYHTQTMPSPQPVPSHGSQPHSPVASQEQQQFHQKQQQQQQTPTPQPEADHWYHFQQPVSVEVTPIDQIPSYSSSVYDSWAPKIEFATDPSLQMPSERIANM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMZ7</accession>
    <name>A0ABR3YMZ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_006051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000246">
        <property type="protein sequence ID" value="KAL1888754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2040">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1888754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="158" mass="18002" checksum="316F8D7FAD051596" modified="2025-10-08" version="1" fragment="single">TPILTVYRLRAVRKTLTPFLTSPYRPTLRDLIAKSIFMTNTSAMSRRLGRSLASIRLARRLASRPPPEVLVERSLIPRECVPGLTPVPLSPAIVAKKRVIERELVKDVLRHWVGTVWTGKARVKAEDIRAWEEQAGIGRVWRLTRFWERVSKNSGLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN09</accession>
    <name>A0ABR3YN09_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Wbp11/ELF5/Saf1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005853</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000223">
        <property type="protein sequence ID" value="KAL1889287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019007">
        <property type="entry name" value="Wbp11/ELF5/Saf1_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09429">
        <property type="entry name" value="Wbp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Wbp11/ELF5/Saf1 N-terminal" evidence="2">
        <location>
            <begin position="4"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="282" mass="31451" checksum="FE99033FA78902AB" modified="2025-10-08" version="1">MVKEKNFNPVQAQRKADKAKAIKKGKAENQALRDEKLSRRNPARIQKQLDDLKVIVTNGGKLSQHEEQVLAGLEKELSAVKKARATLGDKAPVFANHCNDALGKRQRGDGGQRLRRWDQDSTDEDVPAEVRRIPMPRDTPPPIAKQELDKWYAKRRERRAREEELRQIERGGDASKSIPESSSGTMHDGAGQKAKAREPVAVKKVYEAQPVVRDLVKEAVKAFTPLSVLRKLEKSKGRNGLLEPEEADRLEAQGYLQLKNGISVGGTADELKATVEDTDEDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNA8</accession>
    <name>A0ABR3YNA8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit J</fullName>
            <shortName evidence="4">eIF3j</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 30 kDa subunit homolog</fullName>
            <shortName evidence="4">eIF-3 30 kDa subunit homolog</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">HCR1</name>
        <name evidence="6" type="ORF">Cpir12675_005807</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit J family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000217">
        <property type="protein sequence ID" value="KAL1889407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.60">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03009">
        <property type="entry name" value="eIF3j"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023194">
        <property type="entry name" value="eIF3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013906">
        <property type="entry name" value="eIF3j"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21681">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21681:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08597">
        <property type="entry name" value="eIF3_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="223"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="224"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1889407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="267" mass="29508" checksum="9A06DFFB1E5F0297" modified="2025-10-08" version="1">MAPKWDDEEEGVTSAPHSPPPVAPLRREAKFDDEESGDSDVADAWDEDSEDEEEKAKKTAEAEDKKATETAKPKLSKAQRIAQLKTQRAAGLAGDDFDDYEDEAERRARLRRSEIEADLSHAEDLFGSIGVNPNRKGATIGTAVITDANNPTSTVDMTKMPLFNPMTKTQFETLRNTLTPLLSQSSKKPHYNLFLQEFTKQLARDLASDQIKKIASTLTALSNEKMREEKAAEKGGKKSKAAKNKTSLNASRPGITDTNTYEDEFGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNK0</accession>
    <name>A0ABR3YNK0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GH16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005967</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000236">
        <property type="protein sequence ID" value="KAL1888979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF60">
        <property type="entry name" value="GRAM-NEGATIVE BACTERIA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26113">
        <property type="entry name" value="GH16_XgeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH16" evidence="1">
        <location>
            <begin position="5"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="334" mass="35366" checksum="8050A661A381162E" modified="2025-10-08" version="1">MSLFTSVLAVPVPVDESDVSSFGARNWTVVFYDNFANSATSPSTKNWVISTGTRYPGGPANWGNGEVQEYTSSATNLYISSHSDGSPTMESTDPESAQANLLNIVPQRSGSSGYESASTNSVLNSTWTSGRIETSPSFNFVCPEGGQLRMEARFKLGSASPSAQQGIWPAFWALGTSFRGNYNNWPAVGEIDIFETVNGDATSLHTVHCGTNPGGPCNEPNGLSKRIDGGAPSGQWITASVTIDRSNDGRDWRAESLKWRMNGKVVNTLLGSDVGDKDAWAALAHDDHFLLLNVAVGGALPNAMASSSTPMTSTEGGVGSAMQVSHVTVLSRKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP16</accession>
    <name>A0ABR3YP16_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Regulator of Ty1 Transposition</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ESC4</name>
        <name evidence="3" type="ORF">Cpir12675_005715</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000210">
        <property type="protein sequence ID" value="KAL1889612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18437">
        <property type="entry name" value="BRCT_BRC1_like_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18438">
        <property type="entry name" value="BRCT_BRC1_like_rpt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17743">
        <property type="entry name" value="BRCT_BRC1_like_rpt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053036">
        <property type="entry name" value="CellCycle_DNARepair_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47667">
        <property type="entry name" value="REGULATOR OF TY1 TRANSPOSITION PROTEIN 107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47667:SF1">
        <property type="entry name" value="REGULATOR OF TY1 TRANSPOSITION PROTEIN 107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12738">
        <property type="entry name" value="PTCB-BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16770">
        <property type="entry name" value="RTT107_BRCT_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="3"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="101"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="331"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="487"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="596"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="522"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="861" mass="95945" checksum="9E8F2BE1CB9DCC99" modified="2025-10-08" version="1">MEGSKAVFDQCVFVFVPSDLLSTKLIGELSEIVIKNGGSVCAPLDDNDLRTFEATHIISTTIDFPQYVDAQAFMIPVVSHHWIQQALTRGKLPQLRPYSPDPRLIFSNVVVTCSGLSETDTDTIVGATMALGGTENRTITRLTTHICTPYLTEELLAQAKAKGFRGVFVIPHWFNDCFKLGKRIDETPYKLPNMEVFTTDPKDNLKIPSSKGIVGAIDPNPAALPRPVVKGSRAPLRVFQKKAVMLGNDLVLADDLRTTIADLIKESGGSVVGNTDDCDMYIGRYRYGKDYVRASHLCKDVGNLSWLYHLIVNDQWTSPLRRLLHYPIPKEPLKGFEGLKITVSNYGGEARTYLENLITAAGASFTKTMKNNNTHLVTARRAGEKCEAAVDWGIEIVSHLWVEESYAKCAVQPCSNTRYSHFPPRTNLSEVLGQTFFDEAVLRDLYYPGGEDLPKVAQLKRRIRDVANDNVFQRGPAKGTLNYMEEEPPAAAAPKSVKRQRKTYTTDSGGAEFSTPTRQMRAKSSTSTTAGTTSFASITSEMDIDTPVTAGRSAKSKAAKSIQNLVADIKLYERENKRTNSGGVWGGRRAADELEKAMRESTKGRRTEQVDSKEPDGDGQEAHTAKKRKALPDIKYRIMTTGFRRWSNNPKLEEREKARLREFGIKLIEDGNPCQYLAAPKVLRTLKFLKTLARGPILINTSFIDSVLDQDTLLDPVDFLLQDEEYEKANNVNLQEAVARARINKGHLLAGVPIFCSDHVANGKDTYRAIAEANGATWRELTARNVIKPEKPTVDGAPLEPVYLLSSNSAKEQRLYTRFVDMAVNGNMEPRIVLTEWLLAIAIKQEMIWDEKYLVENEKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP64</accession>
    <name>A0ABR3YP64_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000194">
        <property type="protein sequence ID" value="KAL1890101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047404604" evidence="1">
        <location>
            <begin position="18"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="69" mass="7672" checksum="3723ED93D83F2058" modified="2025-10-08" version="1" fragment="single">MKLSTLASLTIAGLVAANDVLYSQRLAKRDPDAPEPFKAKFYHVNDIHAHLDMFSKAGLDCKNPEYGCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPA1</accession>
    <name>A0ABR3YPA1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cation-transporting ATPase</fullName>
            <ecNumber evidence="13">7.2.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Cpir12675_005522</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Membrane</location>
            <topology evidence="1 13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.-" evidence="13"/>
    <dbReference type="EMBL" id="JAWDJO010000192">
        <property type="protein sequence ID" value="KAL1890183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07542">
        <property type="entry name" value="P-type_ATPase_cation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006544">
        <property type="entry name" value="P-type_TPase_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047819">
        <property type="entry name" value="P5A-ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047821">
        <property type="entry name" value="P5B-type_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01657">
        <property type="entry name" value="P-ATPase-V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630:SF8">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12409">
        <property type="entry name" value="P5-ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="422"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="606"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1135"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1165"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1202"/>
            <end position="1224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1248"/>
            <end position="1267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1279"/>
            <end position="1297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1318"/>
            <end position="1343"/>
        </location>
    </feature>
    <feature type="domain" description="P5B-type ATPase N-terminal" evidence="17">
        <location>
            <begin position="221"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="15">
        <location>
            <begin position="460"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase C-terminal" evidence="16">
        <location>
            <begin position="1162"/>
            <end position="1332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="81"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="83"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="100"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF12409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1890183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1372" mass="155125" checksum="081BB5B7CF71758B" modified="2025-10-08" version="1">MADSNNLYHARRQSRSHSQSQARTSRDFYNLGNNPSHASIFEDVEMAHEEVFAGPIAESLPSSVSAFSHRISRVPSNTSFTYFHDDQNDFSDDSDRQDYGDDYPASEENEEGHVDDDIYQNHLRHTSEQAMLNRQDSRLHEDHFVPNDDQTDRSVSFDVDHRPSIDYSASRRRSSTISRNSVHARLLRRDSTTTNGSVFGRQGGSGSSCGRRGQKIHMTNEDLTIFIAGFRSTRLRTAMYILLCIATGGLAFLLMRWLPTYKVKIIGTPALLRECDWVVIENQWGEISIVEVNKRHYGRQLSSIFGSPIRKHRSLLYDDDLDIDPIIGELRAVSYRYVNFFFHPLRDKFVLFSGWKDPEWTDLQIARIGISSEERSTREQVFGQNLILIKVKPTMQLLVDEVLHPFYVFQIASLVLWSMDEYYYYAFAILLMSVVSIGQTLRETKETMMRLRAVSIFDCDVRVLRNGFWRYVNSSDLVPGDVYEVCDPRLSLIPCDSLLLSGDCMVNESMLTGESIPITKTPATNAALRNLDLSAASVSSDVTRHFLYNGTKIIRARRPNDSKDSSDGCLALVVRTGFSTTKGALVRSMMFPKPSGFKFYRDSFRYISVMAAVAAVGFCVSLVNFIRLRMDVSVIIIRAMDLITIVVPPALPATLSIGTNFAISRLKKQSIFCISPQRVNVGGKLDIMCFDKTGTLTEDGLDVLGVRPVSRLNNSFCDLQTTAEDLNFRKLDAEQFRINQSLLFSMATCHTLRDVDGEMLGDPLDLKMFEFTRWTFEEGEQRVGEDGDELAGLTPSVARPPPGFFTQKPGRAELGVVRSFEFISRLRRCSVVVKHFGERSGDVYVKGAPECMRDICRADSFPSNYDELLSHYTHMGYRVIGCATKHMKKMPWLKTQKLKRNEVESDLEFLGFIIFENRLKPSTKDVLVELHKANINTVMVTGDNILTAISVARECTLLDENAHCFVPRFVEGDKGDRDAVLQWESINRPELRLDAKTLLPDAASQSVDVSLPNEISNLQNYSIAVSGDAFRWMIDFGSPQVLERMLVRGKVFARMSPDEKHELVEKLQSIDYMCGFCGDGANDCGALKAADVGISLSEAEASVAAPFTSRVFEISCVPTVIREGRAALVTSFSCFKYMSLYSAIQFCTVSFLYAKASNLGDFQFLYIDLAMILPIAIFMGWGGPSDKLCRKKPTANLVSRKVLVPLLGQMIIIIAFQALVYILVRQQSWYIPPVVHHKRPHIKNSENTALFLMSCFEYIFIGVVLNAGPPFRVKVYKNWPFLATIAVTTLFSAYMLVCPDRMVRKIMELTKMDMGFRLLILCLGPLFLAVSYVFETYVFLWAARQLGVLRTLVTGKEKQRKKYKVILEKTKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPA7</accession>
    <name>A0ABR3YPA7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_005680</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000207">
        <property type="protein sequence ID" value="KAL1889702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="35"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="75"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="370"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="514" mass="56461" checksum="ECBDF3B6532D622B" modified="2025-10-08" version="1">MGPYPPPPLSARSSSSSLQPSASADKHSHYGHLDSCDVCFDDNFKCDRRKPQCSRCVSLNFACHYNQRPLSLHRPQGANVQQRSRQPQQSQPQPDPLGSPLEEAAMLAEINNDLYSSLAHVGLMSHESMLTTTASGERRSQVDEVSRLLGDALHARNDDSSSIRWPALLQSAEAVVEEAKRHPPQTDVLKQYACPPEIIESWNHLERVCSPNDPCEDKIQKVMPRLSHMYSGIDGDARDNDTIYHESRETKAWFLQEMKVIMMCSCSNRAKVACRIIIACLSLLTVYHVNIMGLNGRHLSSATPAHSAGGPTSVPTVPAPGAGFVPNQRRALAFSTIVLPPLPTQGTSRVNALSTYAALNQHLDTLPDVALPPATRPISPEADSSARFAPHSNSPVDSPPRSHDRPATALARKLSDGFNYPNSHNQNNIFPSYEGSRRHVVGDVRLLAELFGSIRFINQVITRYEGASSHIEIPGHRTGYDKAGLEAATRGMSVELKDKLIQVLQDVACLRYPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPB0</accession>
    <name>A0ABR3YPB0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">AAA ATPase cdc48</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CDC48</name>
        <name evidence="8" type="ORF">Cpir12675_005583</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000199">
        <property type="protein sequence ID" value="KAL1889937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19519">
        <property type="entry name" value="RecA-like_CDC48_r1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19528">
        <property type="entry name" value="RecA-like_CDC48_r2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.20.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005938">
        <property type="entry name" value="AAA_ATPase_CDC48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004201">
        <property type="entry name" value="Cdc48_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029067">
        <property type="entry name" value="CDC48_domain_2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003338">
        <property type="entry name" value="CDC4_N-term_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01243">
        <property type="entry name" value="CDC48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF171">
        <property type="entry name" value="NUCLEAR VALOSIN-CONTAINING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02933">
        <property type="entry name" value="CDC48_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02359">
        <property type="entry name" value="CDC48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01072">
        <property type="entry name" value="CDC48_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01073">
        <property type="entry name" value="CDC48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="ADC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54585">
        <property type="entry name" value="Cdc48 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CDC48 N-terminal subdomain" evidence="7">
        <location>
            <begin position="40"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="CDC48" evidence="6">
        <location>
            <begin position="140"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="252"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="526"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="799"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="799"/>
            <end position="812"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="820" mass="89984" checksum="1D231170F48CAA3A" modified="2025-10-08" version="1">MAPSEEHKKKVNLNDPSGAEIKDENDVATAILKKKKKDNQLIVTDGGTDDNSVIALPEKTMELLQLFRGDTVLVRGKKRKDTVLIVLADEELEEGNARINRVVRHNLRVKNGDMITISPCPDIKYAKRISVLPIADTIEGITGSLFDVFLAPYFREAYRPVRQGDIFTVRGGMRQVEFKIDQVDPPEFGIVAQDTIIHCDGEPIQREDEESNLNEVGYDDIGGCRKQMAQIREMVELPLRHPQLFKSIGIKPPRGVLLYGPPGTGKTLMARAVANETGAFFFLINGPEIMSKMAGESESNLRKAFEEAEKNSPAIIFIDEIDSIAPKRDKTNGEVERRVVSQLLTLMDGMKARANVVVMAATNRPNSIDPALRRFGRFDREVDIGIPDPTGRLEILSIHTKNMKLADDVDLEQIASETHGYVGADMAALCSEAAMQQIREKMDLIDLDEDTIDAEVLDSLGVTMENFRFALGVSNPSALREVAVVEVPNVRWDDIGGLVNVKQELKESVQYPVDHPEKFLKFGMSPSRGVLFYGPPGTGKTLLAKAVANECAANFISVKGPELLSMWFGESESNIRDIFDKARAAAPCVVFLDELDSIAKARGGSVGDAGGASDRVVNQLLTEMDGMTSKKNVFVIGATNRPEQLDPALCRPGRLDSLIYVPLPDESGRKSILAAQLRKTPVADDVDLDFIASKTHGFSGADLGFITQRAVKTAIKESIMADIKRTKELEEAGMEIDEESGDDPVPQLTRHHFEEAMQMARRSVSDVEIRRYEAFSQQMKVAGPGAFFKFPDAEAAASAAAGNASGDNFGDAGNDDDLYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ74</accession>
    <name>A0ABR3YQ74_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioredoxin-like fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005359</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000181">
        <property type="protein sequence ID" value="KAL1890496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050931">
        <property type="entry name" value="Mito_Protein_Transport_Metaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12289">
        <property type="entry name" value="METAXIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12289:SF44">
        <property type="entry name" value="OUTER MEMBRANE PROTEIN (SAM35), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G13180)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17172">
        <property type="entry name" value="GST_N_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin-like fold" evidence="1">
        <location>
            <begin position="112"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="343" mass="37231" checksum="93D9DAF1B85E7210" modified="2025-10-08" version="1">MASNATPTSTTTAATAATASCADQTLSEPSALQARPELRSTTAEAATISSISKPGYGPSWMTAPQFIIRLFTKFPLATFEANALPCNTVDVSDDVATLFVFAEDRDRLSYNPTCLRWQAYLRFAHLSYTSIPSTNHASPTGSLPFLLPAASRVAIPCTDPRSLALPMPHAVPVASSRSTMYMALLDTSLRPAWLHALYIAPENTALLTRLYITPTSASRVVQAASLRTLRRAAETEVHMSVRVAASHSAVLRPDTLYADARVALAALEAELALSESGWFLSAVEPTVFDAAVFSYVHLLLDESLVWGDDTLPCAVASFMGLVAHRDRVLNEYWPREERRALKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSU5</accession>
    <name>A0ABR3YSU5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">ATP-dependent RNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">NAM7</name>
        <name evidence="15" type="ORF">Cpir12675_004970</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000154">
        <property type="protein sequence ID" value="KAL1891458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21407">
        <property type="entry name" value="1B_UPF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18039">
        <property type="entry name" value="DEXXQc_UPF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21400">
        <property type="entry name" value="ZBD_UPF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040812">
        <property type="entry name" value="UPF1_1B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018999">
        <property type="entry name" value="UPF1_CH/ZBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF364">
        <property type="entry name" value="REGULATOR OF NONSENSE TRANSCRIPTS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18141">
        <property type="entry name" value="UPF1_1B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09416">
        <property type="entry name" value="UPF1_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51997">
        <property type="entry name" value="UPF1_CH_RICH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Upf1" evidence="14">
        <location>
            <begin position="86"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="C3H" evidence="12">
        <location>
            <begin position="94"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="CC/SHH/C" evidence="12">
        <location>
            <begin position="108"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="C4" evidence="12">
        <location>
            <begin position="154"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="896"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1009"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="896"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="909"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1026"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1048"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="1146"/>
            <end position="1156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1891458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1156" mass="127431" checksum="02E468F84A0F3662" modified="2025-10-08" version="1">MDDKADASVTHQNFDSQSVADPDNEETLLFSGLAGRRRTNDEDNLIDDDSASEDNNHDHDHDNDNDSSVSAAIDDLDRLSITAPEEPVLPAHACSYCEIHNPSCVVKCLVCNKWFCNGRTRGRSAHIINHLVRSRHKEVSLHPDSTLGGTTLECYVCGIKNVFLLGFIPAKADSVVVLLCRSPCASDPSRKEATWDITKWQPLIEDRTFLPWLVHLPSEEEKMRSRHITNDQMSSLETLWKTNPERGIDFLNCTDDIEDEPLPVLLNYNDPYHYHSVFGPLVTMESDYDKELKEAQTEDDLTITWDQALNTRTTARFKLRKIELGDVKLAVGDEMRLHYSSGNRLIWEGVGYVIKIPNNESATVTLELRKTGNDKPVPQHLETGFSADYVWKATSYERMLWALNTFQRDEKSIHGYIFHKLLGHDVTPKPKDRGRHQNLSRKIHAPGLPALNDSQSNAVRTVLQQPLSLIQGPPGTGKTVTSATIIYNMAKQSGGEPVLVCAPSNVAVDQLCERISLTGLKVVRLTAKSREDVESSVNHLSLHEQVRQGQTNSELARLLQLQTEIGELTSEDEKRYRKLLRKAEKDFLNNADVICCTCVGAGDPRLLKKSFRHVLIDESTQSAEPECLIPIVHGATQVVLVGDHKQLGPVIMNKKAARAGLNQSLFERLVHLGMNPIRLNVQYRMHPCLSDFPSNMFYDGDLQNGIGYESRIRNDIDFPWPVKESPMMFWANMGNEEISASGTSYLNRTEASNVEKVVTRFLKEGVQPTDIGVITPYEGQRSFLVTTMQTTGTCNKDLYKRVEVASVDAFQGREKDWIVLSCVRSNDNQGIGFLSDPRRLNVALTRAKYGLVIIGNPKALSKNELWHSLLSHYKDKNCFVEGPLSNLQKSLMQFSRPRPSFRPRNNNPGQNAGLNANHQPHGIYGPTSSASTVGGSGGPGNGSSSRFGSGSGRDFDTGSMMSYIPDDASSLHGSIYNGASLNLKFNNGFLAGLAPEMWPGLPGVPALPRGSRRHARPAESIAGESDATSEFTDATSVVGGNGVGQGGVSLNLGSNGASGGLHSHQQTHHHHALSGSSSAQKDRFNRYIQNGGRMGVNRPLDDDEKSVSTAFQSQIGDPRRGGPGSTVGRPGSLRKGTPAQTESKSRRANGKKTAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT75</accession>
    <name>A0ABR3YT75_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_004920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000151">
        <property type="protein sequence ID" value="KAL1891578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1891578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="343" mass="38205" checksum="82CA8461B3E1041E" modified="2025-10-08" version="1">MSLQTHIFYPDSSISQTRVPYTTWSANSGVWNSDVFQPHDSSSPWPDSSNNSSYCASSYTSSNPSSPAHHNYSTFSPQMSGHAQCIDPALTESGMGNMASSIMFNEPSVMDNGPHYDGDFSSIALPIDAMHPMDIAWNEGTLSAADFRSHPRTQPEVSNPVVGFIVAPSPNPAHTPALSPRGLPDLAPRSPGFTCHEPECKQRMFKRKADLQRHIHHIHLPADQKKTFLCDYRRCNRAKMESPFHRRDHLRDHYRDYHKDEVVKQGTLPAAARRRKAAAGSSSCSVPVSALDALDLEDIHRDWWRCAKCLHRLNNKLTDCQNCKAPKSKGKRSGVTGKVISKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTF3</accession>
    <name>A0ABR3YTF3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein disulfide-isomerase</fullName>
            <ecNumber evidence="2">5.3.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_004991</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Catalyzes the rearrangement of -S-S- bonds in proteins.</text>
            <dbReference type="EC" id="5.3.4.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000155">
        <property type="protein sequence ID" value="KAL1891377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00238">
        <property type="entry name" value="ERp29c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1150.12">
        <property type="entry name" value="Endoplasmic reticulum resident protein 29, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011679">
        <property type="entry name" value="ERp29_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036356">
        <property type="entry name" value="ERp29_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051063">
        <property type="entry name" value="PDI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45672:SF11">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE C17H9.14C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45672">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07749">
        <property type="entry name" value="ERp29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47933">
        <property type="entry name" value="ERP29 C domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="7">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum resident protein 29 C-terminal" evidence="8">
        <location>
            <begin position="86"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="193"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="225" mass="24292" checksum="4A510F011871EEA3" modified="2025-10-08" version="1" fragment="single">WEKAADDYKHDESVLIAKVDCEAPNSKVLAKKQGISSYPTIKWFPAGSTVGEPYDGPRNEEGILAFVNEKAGLHRTSGGSLDHVAGTLASLDSLVVKLTGGSTFSDVLTQAKAESSKLSADVQKKSAEYYVRVLTKLGENHEYAKKELARLQGMLAKGELASEKRDELTIKANILKKFEEVKIAAGETVKNIIDKASEAKDATAEKAQAAKEAAEKKAAEIKEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTI9</accession>
    <name>A0ABR3YTI9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_004852</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000148">
        <property type="protein sequence ID" value="KAL1891666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1891666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="216" mass="23594" checksum="978FAADE40219E00" modified="2025-10-08" version="1">MAIDDVLYDVSFQHVDAQQKLKHAVVLAANARNLTSSLDSAQALRLSTMAMSPASTIVDADECNLRLPLPRKTTITSVTDTPAVFFHGYLSSPVNSDPYYLKRFRSRQVGVHSSNAPLQSPTMTSAALELASSQNTRLEATVKSTGPTAETAMSAVVQAARARAIYNHAAAHVPLRYRVGKTERKMFVSSPLRKMLATRFVTEKIQQGIQLSCRMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU76</accession>
    <name>A0ABR3YU76_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Autophagy-related protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_004818</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000145">
        <property type="protein sequence ID" value="KAL1891813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007135">
        <property type="entry name" value="Atg3/Atg10"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03987">
        <property type="entry name" value="Autophagy_act_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0072">Autophagy</keyword>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="206" mass="22495" checksum="0D6DE7155F78BFB9" modified="2025-10-08" version="1">MDFKAYPWLSADEFTECCHHLEARYCRATLGPLRRRWKLSAISSLDLCGASIGMGSSGGYVTYLQIVRPLDVALDSNGLAAEIEKLGVGLESWGQSSCSSSEIDAAGEGLLDSSMETDELRDEAVLRVSGTEGDGDGDVLHNVGRVIYEIHLHPTYRIPCLWFSLEGLPVDEPAFDIETVFRRLVPDQFKGGLRALGHMGGISMDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUM2</accession>
    <name>A0ABR3YUM2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Endonuclease</fullName>
            <ecNumber evidence="8">3.1.30.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">NUC1</name>
        <name evidence="11" type="ORF">Cpir12675_004860</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the DNA/RNA non-specific endonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.30.-" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000148">
        <property type="protein sequence ID" value="KAL1891674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00091">
        <property type="entry name" value="NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.570.10">
        <property type="entry name" value="Extracellular Endonuclease, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018524">
        <property type="entry name" value="DNA/RNA_endonuclease_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044929">
        <property type="entry name" value="DNA/RNA_non-sp_Endonuclease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001604">
        <property type="entry name" value="Endo_G_ENPP1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020821">
        <property type="entry name" value="ENPP1-3/EXOG-like_nuc-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040255">
        <property type="entry name" value="Non-specific_endonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13966:SF5">
        <property type="entry name" value="ENDONUCLEASE G, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13966">
        <property type="entry name" value="ENDONUCLEASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01223">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00892">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00477">
        <property type="entry name" value="NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="His-Me finger endonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01070">
        <property type="entry name" value="NUCLEASE_NON_SPEC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase" evidence="10">
        <location>
            <begin position="110"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="ENPP1-3/EXOG-like endonuclease/phosphodiesterase" evidence="9">
        <location>
            <begin position="111"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1891674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="351" mass="37851" checksum="A247B298044F956E" modified="2025-10-08" version="1">MSKSSFALMAALGAGGGAAATAALLLMRFDAHEAAPFKSVPVPGPVTASPSMIVSPGGAHGSAVMPPLAGAGAGSAVVAGSDSAVGGLSPVNPAGIFDYGFTGCVSDVAIRSALVSGFDRQRRNPAWVAEHITRESLAQRGGDRKHSAFVEDTNIPSKFRALLRDYYRSGFDRGHQVPAADCKWGQTAMDDTFFLSNMCPQVGDGFNRDYWAHFEDLCRRLTHKYPSVRVVTGPLYLPKREADGKWYVKYEVIGSPPNVAVPTHFYKVIYAEDGREGGNVAIGAFVLPNAVIPNHKPLRDFEVPLEVVERASGLEFANKLPVQRRRRLCTDVDCSLVIKEYAKQQQVLTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUT8</accession>
    <name>A0ABR3YUT8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histone acetyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_004805</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21992"/>
            <dbReference type="Rhea" id="RHEA-COMP:9845"/>
            <dbReference type="Rhea" id="RHEA-COMP:11338"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:21993"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000145">
        <property type="protein sequence ID" value="KAL1891800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051236">
        <property type="entry name" value="HAT_RTT109-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013178">
        <property type="entry name" value="Histone_AcTrfase_Rtt109/CBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016849">
        <property type="entry name" value="Rtt109"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31571">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31571:SF2">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE RTT109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08214">
        <property type="entry name" value="HAT_KAT11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01250">
        <property type="entry name" value="KAT11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51728">
        <property type="entry name" value="RTT109_HAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="505" mass="56576" checksum="A5D9CBEFC16BCF4A" modified="2025-10-08" version="1">MDATPKTAERKVASLLVDKLASVLPKGFKFGVYHVSTPPTLRDPLYSPLPNQKPDRTYCESHFLAVSIDVTSSDGSVKPVLVLALEAFLYTTKYTTTLFVSKADSTGYLHLLGLPAGSTSPIRSISTAFIEYLIEERRRKNVQFVVSLFARAQDQYLFPGSVENKKKHVLDDKGLVKWWCRVINPIIEAPPLAANREAWKSIKAYLVVPGLDAYETRALVPRTAAAAYNWSFTHPLGILSQIRTKPGTELPPRCLIPMYPDDPKSRFRVELDEEAAKGAQYKNKGLWKSVHTIDQFWEMMAFRQECSSGRMTGFLWVVFDTLESRTDEADSEKVSPPLVLGLKPKTQKQKAKKKKKLTGIIPLREPHIKTHRKNNLLKKHALTAYYTWPLASRGDVIVDDADYKQIYELLLRLDFAKIDIAVSSSHRWIREVGGGKTWGTLVEGTAETPAAMAQTAEPNGLMVNKMVVNNLSGLVKRKRQVSGCETTPPVANVPSAELLRKKQKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUX7</accession>
    <name>A0ABR3YUX7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_004892</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the REXO1/REXO3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000150">
        <property type="protein sequence ID" value="KAL1891583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06145">
        <property type="entry name" value="REX1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034922">
        <property type="entry name" value="REX1-like_exo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047021">
        <property type="entry name" value="REXO1/3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801:SF115">
        <property type="entry name" value="FI18136P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801">
        <property type="entry name" value="RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="8">
        <location>
            <begin position="330"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="30"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="227"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="44"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="244"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="714" mass="78218" checksum="7F8185064B95E532" modified="2025-10-08" version="1">MGKKQRKQANASMSLALQQAAISRDVVVAAPKSGAPASSVSSIESERSSLKRSAPHDNEDSDNEAELRDKPANSNNDSWAMASNKRKKLKVPSTKSSNYPSIQLLKNSRLQSKVSLDAWRDLILYVFADGVAPQWVSISNRSHIRKFVTVMVPGLEEAMFRANVDYRVFDEALAGEKEALASGAKVSNPDDYMPQRMNKDTLHPTLAPLADMFDLLWPVRAPGDDRYSKLHSPTGTFLSAPKPKGKDDKSNNGKKDVWRNERTRITDFIATEEELAENDYVVHPVLLSDPAEAAAFKLKDGWVMTPITSLDESEVPEGEIENGSITAGREILAIDCEMVMTGPTEMALARISVVSWGGDVVLDELVKPSKPITDYVTQYSGMTPAKLDAVTTTLADIQAKLLDLLTPRTILIGHSLDSDFRALRLCHPFIVDTSLIFPHPRGPPIKQSLRYVTQKYLNREIQKGGASGHNSIEDAKACLDLARLKCEKGKSWGLPEGGGENLFSRLARTGTTYKAQGGAAALGGKTTGKTSAMIDWGNNTKGPGSRATHHIGCRSDDEVVAGIQRAVEGDTDGAIIPGGGVDFVWARMRELEAFRGWWNNARDAAAGLIPEFGPLPETSPYDSPLQAQLAALVERLQKIYATLPPCTGLMVYSGSGDPRELSKLQAMHTKWKKEYNMPGSKWDQLSVKWTDTEEQAMRREVRIARAGMGFITIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX28</accession>
    <name>A0ABR3YX28_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sporulation-specific protein 22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SPO22</name>
        <name evidence="10" type="ORF">Cpir12675_004351</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000120">
        <property type="protein sequence ID" value="KAL1892941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056751">
        <property type="entry name" value="PAS_13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039057">
        <property type="entry name" value="Spo22/ZIP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013940">
        <property type="entry name" value="Spo22/ZIP4/TEX11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40375">
        <property type="entry name" value="SPORULATION-SPECIFIC PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40375:SF2">
        <property type="entry name" value="SPORULATION-SPECIFIC PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24990">
        <property type="entry name" value="PAS_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08631">
        <property type="entry name" value="SPO22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0469">Meiosis</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="ERT1/acuK family PAS" evidence="9">
        <location>
            <begin position="671"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="215"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="153"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="225"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1892941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1694" mass="186148" checksum="FE6B95E298434662" modified="2025-10-08" version="1">MNKPSDGELVPTCFGPPSTAAHTIPHVTGAPPYSSLTSTPIATDKPAGPSNGTGANADLAAPSDVSTQAHAPLAASNPVDQMDVSEQGTAPITTTMTATPVVTAAPAPKAILPASAPAIAPAPVARSAPACVSTSVPVSTPLAAPVLAPYAPSSTATPATTHTPIKPHPQSQQAAASVATIPNPNLVHTYAAGGNDAGTTTAGSTTSAASAVTTVAVSAQASHGRQKEKDRKEHAPPQGVEPAPKKRRKVNHACIYCRRSERPCTRCIKRNIGHLCHDEKREPDSKKVKNAAASTVAASSAASALTNTQKQRQVQQQQQQQQQQQLLQQRQAQVSALDVSASVTAAAVAAAAAASNFGLGQEDMLHLVPPVTVAELQAQAGGLNSGSINPFTSISELFMGHNHFHDIPNIHSSYMAASEVNNEFQLLNDFLHTSMLDDGLGLSNDESTADPAATYSNNSRPEILNGFASLNGSNPLAGNANPHNSAAGGPPVRVDGLSVAAIGSMLPPPDPKIPTSIAPDTLNASPTTAPATVVTTIAPSSTIAAPGTLPVLNVPPRDRDKARRDYYLQAADPTGNDNPEERMQLVLKAKYEAGLLKPFNYIKGYQKLSTYLDSHIALTSKQKILKCLNRFRPKFREIAQALTDMELVVVEMWFEKQLLEYDRVFASMAVPACLWRRTGEIFRGNKEMAELLHVPVEELRDGSIALHQIITEESMVRYWEEFETIAFDPDHDTLLTACSLKSPDDSTNVTVNCAFSFMIHRDDYKIRDKGFCDTICKTITTSVDNPSIKSLSSDISSHARTADKLCQKRLLVYARELNELDRSATSLWNLTCRLLRKKDESLGVEQANYIYPRRQLFVKATTFAFQLLDLTRWQGGTEALKSVVTETQLGIYRISLSAARACLDESELDSCLVVLKRSVEFSEGLARKEELTDEQKLILSKYDAEYFVLRTSLGRLDVANHMYDKSKTLFQSLDSVYSENLAEVILDIGKGLMRKKDYKLGVTWLKRAYEIITLHHIDKLSRLGIEQRLTIMQALVRGHLLEETPEGREHANELICQLESEIGQLPAVLLLRIHALKAAPQEEFDSEAFASTLERFSRTPGLSESQFKTVLHEAKMLKERSPFKALSVARTLLCDVAIGSGNHDWISKSLIIVVWMYAALDEPDTDHSLSITINNVHQAIQAPVDSMTAGAIQSVLWKRIEASVTKARLSDAETWCQAALHPLFENGGVANQGKLGRKLIFCALEKSDFEKAKEVFHDLPESTQKEQATAFLMFKVATRSKDSDFAAACLRNITHATKASKDILYACVIDSQYAGNLDTAIIAMKNLMEVTEAVPDSNMHVPSLMRCTIRLLYQKLDRGVMNELEDIATDLCNVFEAALRAIEKLPKNAKGGKLFPTQELDWFNQNSYNTALKHVDTWPPMLVCRLMKVCLAITEFYPEDISISASHDLSLKRLCGNFVISAALAALARSEENVKERHQAYLELRKHVTAYDEEFEARKDTYEPYIQKDLMAKLSVLYVFDFEAAAAQKEWDDMRTIVGKSVATCPSAEMLKGMGDYMLSLIDIPPRAELYRILQLIINEIWKLEQFDSAKLAKYMRCLFQVVLPYSEDLALQTLNNVLTIAKEGPAKSTIFPPDELEWITIMAFNHATDLWSSGNDEAAKTWFEKALSLGHYREDDGVFEAHLQERFMKLQWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXF3</accession>
    <name>A0ABR3YXF3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GH18 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004298</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000118">
        <property type="protein sequence ID" value="KAL1893064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050542">
        <property type="entry name" value="Glycosyl_Hydrlase18_Chitinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45708">
        <property type="entry name" value="ENDOCHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45708:SF60">
        <property type="entry name" value="III CHITINASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G03850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH18" evidence="2">
        <location>
            <begin position="11"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="316"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="359" mass="39288" checksum="BFC559BEAC7A6AE4" modified="2025-10-08" version="1">MSAFPLATGTPRVVVYHQTQYHQKRYVSLQPLVSTPGVFVTHLIVAAIHVNENPGHLTLNDHPPTDPRYDVLWQECALLQASGTKVMGMLGGAAKGTYARLCGDVVETPSPGGIDGNTSGSATFEAFYRPLAAFIRAKRLDGLDLDVEESTSLPGIIRLIDRLRADFGTAFILTLAPVAPALIDPRANLSGFSYAQLEAARGHEIAWYNAQFYCGWGMLADPMQYANIIGRGWRPERIVAGTVTSPNNGAGFVEMEDLAASVIQLSEVYPTFGGVMGWEYFNSRPGGLEAPWEWAQWMTSLLGTEEGRVAAITEAQTRKAQWQKGSTSEERKKKGKKRIAASVPNEFEYFTDGEKNEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYA8</accession>
    <name>A0ABR3YYA8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pho80p cyclin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PHO80</name>
        <name evidence="2" type="ORF">Cpir12675_004422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000124">
        <property type="protein sequence ID" value="KAL1892723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20558">
        <property type="entry name" value="CYCLIN_ScPCL7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF117">
        <property type="entry name" value="PHO85 CYCLIN PHO80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="416" mass="45179" checksum="BAEAA743A207A124" modified="2025-10-08" version="1">MNASSVPIFAQSTLSTLASETLTHTIPPSDPHGHSYQPRQCTMQHPGSSTSHTATIAELTSISPLSVSIATTPSATMSPGVVEDRTTAQSTASPSGVGPGTPSTITRPTFSPQKQPQPGRTKNSTLSPQKRRGSSSIEGPPDNKSTSLISQTQPIDEPRASPKNIPAKRVRHNSTPVKVLPIHYEMCQVDDLVVLIAHMLSELIETNDSLALRGSGSLTRFHSRTSPGISVRDYLNRLAKHATLTPPLLLSMVYYIDRLCTLYPDFTINTLTVHRFLITAATVAAKGLSDSFWNNTTYARVGGVRVAELKMLELEFLYRVDWKIVPNPEVLVAYYTGLVDRCPGFDLEQEKYQGHEEDVQDEELVVAEAESEISDDATGSIPKVAATAKESEDSRLMEEPAQSSIPEEQGFNPAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYM1</accession>
    <name>A0ABR3YYM1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mannan endo-1,6-alpha-mannosidase</fullName>
            <ecNumber evidence="3 8">3.2.1.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_004288</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Random hydrolysis of (1-&gt;6)-alpha-D-mannosidic linkages in unbranched (1-&gt;6)-mannans.</text>
            <dbReference type="EC" id="3.2.1.101"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyl hydrolase 76 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.101" evidence="3 8"/>
    <dbReference type="EMBL" id="JAWDJO010000118">
        <property type="protein sequence ID" value="KAL1893054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014480">
        <property type="entry name" value="Mannan-1_6-alpha_mannosidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145:SF36">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016302">
        <property type="entry name" value="Man_a_manosd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="423"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR016302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1893054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="448" mass="48952" checksum="E7772D54D519C116" modified="2025-10-08" version="1">MAGLMLQPTAAIDVNFDDTQSVLDAASTISYGLLKFYTGNNTGDVDGNLPSPYYWWEAGAMFGTLIDYWWLTNDTSNNDAIKRALMHQVGADNNYMPENQTRSLGNDDQGFWALAAMSAAESGFENPPADKPQWLALVQAVFNDYASRWDETTCSGGLRWQIYTFNAGYNYKNTISNGCFFNIAARLARYTGNSSYSDWAAKIWNWEKDLLFINTDWEVEDGAHTDDECKDMTKVLWSYNFGIHMHAAANMYNVTGDQTWLDATNGILKKTTELFFKENIVYEPACEPFGTCNNDQRSFKTYLLRWMAQTAQLVSSTASTIQPFILASGKAAAATCTGTADGFKGIANTACGQKWYSGSFDGINGVGEQMASLAAVMYNLYPSSHLPLSATSGGTSTGNVDAGGSSTNADGKTLSKITTGDKVGAAFLTMLVISGLLGGMFFVFYESM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYS0</accession>
    <name>A0ABR3YYS0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HpcH/HpaI aldolase/citrate lyase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_004203</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000114">
        <property type="protein sequence ID" value="KAL1893225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011206">
        <property type="entry name" value="Citrate_lyase_beta/mcl1/mcl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32308:SF0">
        <property type="entry name" value="HPCH_HPAI ALDOLASE_CITRATE LYASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32308">
        <property type="entry name" value="LYASE BETA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G13030)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015582">
        <property type="entry name" value="Cit_lyase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH/HpaI aldolase/citrate lyase" evidence="4">
        <location>
            <begin position="11"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="326" mass="35326" checksum="5D43DF75D8579E5E" modified="2025-10-08" version="1">MAAQSANIIRRSLLYVPASSEKMLAKSLHIKSDNITYDLEDSVALHKKFDARSLLTTHLASIHPVAGRPAAWKTNTELCVRINAVSTPFALADLTSLASSPSLDAVLIPKVNSAADLSFVTDVLRHIAPERHTQNSPNPIKIIALIESARAIMNLSEICSASPFLSGLVFAAEDFALDLSITRTHSLAEFLYARSAIVTAARAFNLPSAIDLVCTSYRGEEGLHRLEEECINGRNMGFNGKQCIHPTQVGPVQQLFAPSQADLTWAARISIANEKAEAQGRGAWTLDGKMIDAPVVNKARSVLEKGVKCELDVASIMNSWKDQSPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYT8</accession>
    <name>A0ABR3YYT8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">1-phosphatidylinositol-3-phosphate 5-kinase</fullName>
            <ecNumber evidence="1">2.7.1.150</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">MDM12_1</name>
        <name evidence="15" type="ORF">Cpir12675_004260</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.150" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000116">
        <property type="protein sequence ID" value="KAL1893114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000285">
        <property type="term" value="F:1-phosphatidylinositol-3-phosphate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03334">
        <property type="entry name" value="Fab1_TCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17300">
        <property type="entry name" value="PIPKc_PIKfyve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.810.10">
        <property type="entry name" value="2-Layer Sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.800.10">
        <property type="entry name" value="Phosphatidylinositol Phosphate Kinase II Beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044769">
        <property type="entry name" value="PIKfyve_PIPKc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027483">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002498">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027484">
        <property type="entry name" value="PInositol-4-P-5-kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45748">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45748:SF7">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01504">
        <property type="entry name" value="PIP5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00330">
        <property type="entry name" value="PIPKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51455">
        <property type="entry name" value="PIPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="13">
        <location>
            <begin position="409"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="PIPK" evidence="14">
        <location>
            <begin position="2310"/>
            <end position="2640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="66"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="204"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="272"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="589"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="643"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1123"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1772"/>
            <end position="2024"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="2040"/>
            <end position="2238"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="1242"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="204"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="224"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="238"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="589"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="646"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1142"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1167"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1801"/>
            <end position="1811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1821"/>
            <end position="1836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1852"/>
            <end position="1865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1884"/>
            <end position="1893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1926"/>
            <end position="1938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1939"/>
            <end position="1954"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1987"/>
            <end position="2014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="2041"/>
            <end position="2051"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="2187"/>
            <end position="2198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="2217"/>
            <end position="2230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1893114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="2666" mass="293500" checksum="D27922F26598F064" modified="2025-10-08" version="1">MSNLNNTANAQPTASTTPAATSTTATITNTATTATTATTATPATPATTATAATTTAATVATAIASSQIPPPSSDNTSFHQVPSNAPSITSSQQQADREHIAQTLDKIHTTASQSAYLTTFTEIGSPRQSTLPPKEKISESVPAGLSGLYNRFKDAVSGASSSKAVPQNYRLQLELDDAEIVAAAAAMAQSPGLAPPALTAALSMEQQPPGSGQSTMAQAVALTPGPRSSIGSRQSISGLNNTAGTSSAGTAEDSILNDLDAEATSDLSRRASGIDGASATPSVQGDLPAAKADPGIPHAVKSPVSPLTGDSQPVASVIVNPIPTALASSSKAPKSNIPAVISKANEPNMAQASPIHTSAHGSVYTNYDIQPRPARAPESHASEPVVESAYPKLASMEKRVMSKEFWMADETCKECYSCSSVFTAFRRKHHCRLCGLIFDSKCMTTLPGEHFGVNGVLRVCKTCREFFQSRLEDSSDSEAETYLARFVGYRGDTAPNVPVQVTPEADNSTSIRAADEEDYRPSSTPMMAIPGTRHGPDGAPVLEIEPPQLNRAGSSKSLRALANPRLHTSGHKRHHSKHNLHAFATVHGHHSPHLHTHSAHATSQAQKKDEKVPFRKPLPHKHKAKLSAFHDDNIIDPELQDYMSDGASSGDDQTNIASSNQEFGSTSFENDKSTFGSFLTASRRHRMRAGDKSVSGLSFTSKALEETISPSLHGTVSRPTRRRNLSIVSSVGHFMRSPRPKSSIFKFSNIVNEPVFIDSSAESHGPDPERLYASDPGYDHSIPKVNLSPLAENHFRRLLCQLLQDNGIENIPQWEKALVPIIQVCTDEVAPDTDEADYMDIRHYVKIKKIPGARPSDSVYNAGIVFSKNVALKSMPRKIIRPKILLLSFPLEYQRHSEHQLIRIDPVIAQEREYLRIVVSKIVQAGPHLILSSKSVSGIALQSLSDANIAVVYNVKQSVMEAVARCAEGIVIESLDMLALPDVPLAQCGKFEVRTFVDSAFPGGKKSYIFLSDCMRDLGGTITLRGSNISMMAKLKQIVEFLIYVLYNLKLESSMLRDSFIHVPEYLPPSIKATTGSVPEALLSRSTESSDQKVDFPSTQAMAVVPAKTASDTDLLAQGTEEQKSLGRTYGHQSAPAIATQDNKKSREGNFEAHEETPGVVDPSKVTAISGATPTTTSSTTDIETTRDSTTSASKPLTASANKDDSLDMPSYYGDIVDRFESKILSSTPFVKFTQPYLLQKARLLERRLNELRRLKEQYSVELGKEKTEDGDGGEQRFQLVQPEMLHAIGQNVPRQVLRIIHAAHEVEYNNFLHSYHAQTRLWEGVIKSNIDLCDPNEHQTLVMLQSTICTSTKIPCSEPSLVTMRFYIDRSTDFGMENDSTLGQFLEQLYHDQNSKCPSNCTKTMMDHHRTYVHDQRIVTVFTEPNPAPMQTEVIMMWSYCKRCKKDTPMVPMSELTYRYSFCKYLELLFWGNGLTLDQSLGCPHDYHQEHIRYFTIADVRVRLHLDPIDLLEIVVPLKRFTWKVEHDIKIKNDVYIKYRDVWLRFMASVMSRLKSIRIDSVLPEKAESCREEIDRLLKKSQEDQRDLIRTLQDIYMNTMYYELIPFNAVSRKMMDLSEDWNFAFKEFEAHFLPDKDMRQVTMLQLRKMFSEDYTAARDALPNQETAIDGEGPQLAVDGDGGGSFGQADDAMQDVSSGEKIRLDDRQLTMLGDINTSDGKTVATASGGISAAVPVTQDSNDASDLGAATLGAMAVETDVSPAVLKNEANIATQKPPEIFPNSHALEPESILDSGPSQDQSPEHLTPESRRASSPREGGLSQSQSSRAASQARTRSPTPASVDVAGGGDLSLSERIEIIRKEHNLQDASDAMESEPSRPRPGPRRSVSSSIPSAGAFLPRASNSQTHRTPPKALPGGRVIGKEGRSASSRGTSTNGITSSGDQDSSSLDVSQSKKLSERLGLKRNKGGSAIPRPLPKRTPKVSALARHFEQLSREFEIERDRDRKKREEKEQLRQPRSMLPRTSATNIVVYDNVSAAVAEVEQETEPELPELPEPKPELKPRRKVKRPPMFPKLIKDRGSQSGPSASLQRLPLNQRLAVGPESTTKAFGKEDTGKSSVNAGIIRPGLKPQNEQKTEGTETPKAQQTEQSEARSEISSEPQALADSQAISSEETQVGAETHPLEENQDQAQSAPQEPSGQEQEQDQDQDQEAVSNIDPHAKKAEGSGKASDDEAGSDNEASVYDAQDVEVLPVYQKNSLLKMLTNFWAERSSSGWAPLDFPITPMEHIFTDSEIVIREDEPSSLIAFALSSSDYRTKLAESRYNVHKHWHPGATSPDDYEEDTPAAMGSEAEAAYQKDLERELVSPTGSHVKFQFQAGSSKMHCKIFYAGHFDAMRRKCGLAERFIESLSRCIAWDSRGGKSKSVFLKTMDDRLVLKSLSTIETSAFLNFAPSYFGVMAEALFRDLPSVIAKMVGFFQIYIKNSVTGVDLKLDLLVMENLFYDRAPTKKFDLKGSMRNRKVDPTGAQDEVLLDENMVDYIYESPLFTREHSKRLLQSSVYNDTLFLARQNVMDYSLMVAIDEPRQELVVGIVDCIRTYTLDKKLETWIKDRGLVGGGRSRPTVTSPREYKSRFRAAMDRYILQAPDCWRFFNPHEPRLRPRFEADEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZI8</accession>
    <name>A0ABR3YZI8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sulfhydryl oxidase</fullName>
            <ecNumber evidence="6">1.8.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_004005</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2</text>
            <dbReference type="Rhea" id="RHEA:17357"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:16520"/>
            <dbReference type="ChEBI" id="CHEBI:17412"/>
            <dbReference type="EC" id="1.8.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.3.2" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000105">
        <property type="protein sequence ID" value="KAL1893658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.310">
        <property type="entry name" value="ERV/ALR sulfhydryl oxidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039799">
        <property type="entry name" value="ALR/ERV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036774">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017905">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12645">
        <property type="entry name" value="ALR/ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12645:SF1">
        <property type="entry name" value="FAD-LINKED SULFHYDRYL OXIDASE ERV2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04777">
        <property type="entry name" value="Evr1_Alr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69000">
        <property type="entry name" value="FAD-dependent thiol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51324">
        <property type="entry name" value="ERV_ALR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 6" id="KW-0274">FAD</keyword>
    <keyword evidence="2 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047208309" description="Sulfhydryl oxidase" evidence="7">
        <location>
            <begin position="28"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="ERV/ALR sulfhydryl oxidase" evidence="8">
        <location>
            <begin position="59"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU371123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="181" mass="19720" checksum="C4F0CAFC3155B967" modified="2025-10-08" version="1">MARKTPILLAVAALLSIMYFFSGPGSGLSAADYAMPKFDLSQIGDNILKGGSIAPKLGNATAKAELGRASWKVIHTMMARFPEKPTEDESTALLTYITLFSRLYPCGECAAHFRKLLAKYPPQVTSRNAAVGWACFAHNIVNKRLKKPIFDCANIGDAYDCGCADSDKAMREGHDTRLELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZR3</accession>
    <name>A0ABR3YZR3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">40S ribosomal protein S3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">RPS3</name>
        <name evidence="10" type="ORF">Cpir12675_004237</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000115">
        <property type="protein sequence ID" value="KAL1893218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02413">
        <property type="entry name" value="KH-II_40S_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="entry name" value="Ribosomal protein S3, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057258">
        <property type="entry name" value="Ribosomal_uS3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_uS3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018280">
        <property type="entry name" value="Ribosomal_uS3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005703">
        <property type="entry name" value="Ribosomal_uS3_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003219">
        <property type="entry name" value="PRK04191.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01008">
        <property type="entry name" value="uS3_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11760">
        <property type="entry name" value="30S/40S RIBOSOMAL PROTEIN S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11760:SF32">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="Prokaryotic type KH domain (KH-domain type II)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="Ribosomal protein S3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00548">
        <property type="entry name" value="RIBOSOMAL_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="KH type-2" evidence="9">
        <location>
            <begin position="25"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="251"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1893218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="264" mass="28803" checksum="B96CDAF81B78C7F4" modified="2025-10-08" version="1">MASVTSAQISKRRKFVADGVFYAELNEFFQRELAEEGYSGVEVRVTPTVTDIIIRATHTQEVLGEQGRRIRELTSLIQKRFKFPENSVSLYAAKVQNRGLSAVAQCESLRYKLLNGLAVRRACYGVLRFIMESGAKGCEVVVSGKLRAARAKSMKFTDGFMIHSGQPARDFIDTATRHVLLRQGVLGIKVKIMRGADPDSKAGLQKALPDAVTIIEPKEEQPVVQPMSQDYGAKAAAAAAAAAESQRVEEEGAAVEEEVAAAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZZ7</accession>
    <name>A0ABR3YZZ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Clr5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004058</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000107">
        <property type="protein sequence ID" value="KAL1893627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025676">
        <property type="entry name" value="Clr5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788:SF3">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14420">
        <property type="entry name" value="Clr5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clr5" evidence="2">
        <location>
            <begin position="414"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="511"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="111"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="319"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="921" mass="103766" checksum="DFDF479F451EE6C6" modified="2025-10-08" version="1">MNGVHLNNQQYNPSTMRYASDRPDGPDLNLEVFDADSWDTTDYGLAASSSVHGGLMSNTTMPPDRTIPITLPILSNMIDPLTFTQQSPDQISPNTHYQTSGSVVLPDPYSMQSQPQPQPQSQSQLQHQANQQQPLPQALPQTMAQPMPQSLSQSLPQSLPQTQQQQKQQPLYSVQLPTTIPQPQSTVTIPIETQLPMPAYTNQQQQMTPTSEINEGSRMWSSISVSEIDDLPKPWAAALEMANTDKTWTNISDMNNMNNHPKMWPSDNDIMHSQQQQPTHLPVWVPIHPATGTISPFVRISEVIDDEVPLSSGNGTRISHSPLSAPSSSIQGSPHQYQPQSQQNFPSQSPPLWSQARLPAVPLSSYSKAQPVSESNDRPLSQQYDERPSSGVSSNHQPELSPVAAGGTKSWATPADWIQYRDCITRLYIEEDKPLKEVMDIMARDYAFCATEKMYKIKIKKWNLKKNLRENEVQAIIQQVTRRDAEGKPSAVMIHGKQFELTQIFRHAKKKGILKSQRRSRKRRAQEKEPAVEQDVPQYVRIYTPTPARESPQFTLRAPDALHVPEQILCNLGVWMNGKVQSGAWNYWMKSYALFNETTETKGDPTGASVTLISDFYNHFLQGLQTLRTTRDIPKATRSFNIAFATLKNVMVLDDPRLMAMLLLTGLRTEKEGHGRDLGEMLWRYVRELSPCCVGAHSPLNRVWGTIATAFIYNDVGQSMVLMRFLADQIKTWADNSSAMYVDFFMFQSEIERLSFGSSPATRATLRQILQEARHSPMQDYDNIVLQKNVCHQIARSLIKDNHPEEARTVLLQTPTAPLHNSRSARVVYLDLLANIELECGMVDTAAEIMEKAVTQSTALWGELSSSTMYMVDTLIKIYSQMGALDRADALQLDFSRRERFLESYHGEQMPQHIPAVQIGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z043</accession>
    <name>A0ABR3Z043_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_004022</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000105">
        <property type="protein sequence ID" value="KAL1893675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1893675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="80" mass="9000" checksum="9277E614548D5EB5" modified="2025-10-08" version="1">MTGSGLASKCYILPVPQNVPGDEVEIETVISHRGWIDWYHYNLPWETPEDETITLAVSNNSIAFQPMATWAVLPKRETPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0G5</accession>
    <name>A0ABR3Z0G5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Endoplasmic reticulum-Golgi intermediate compartment protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_003801</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Plays a role in transport between endoplasmic reticulum and Golgi.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Endoplasmic reticulum membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Endoplasmic reticulum-Golgi intermediate compartment membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Golgi apparatus membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ERGIC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000096">
        <property type="protein sequence ID" value="KAL1894113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045888">
        <property type="entry name" value="Erv"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012936">
        <property type="entry name" value="Erv_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039542">
        <property type="entry name" value="Erv_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984:SF81">
        <property type="entry name" value="ER-DERIVED VESICLES PROTEIN ERV41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07970">
        <property type="entry name" value="COPIIcoated_ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13850">
        <property type="entry name" value="ERGIC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter N-terminal" evidence="8">
        <location>
            <begin position="29"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter C-terminal" evidence="7">
        <location>
            <begin position="188"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU369013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="382" mass="43177" checksum="F5C4CF73C5832380" modified="2025-10-08" version="1">MMDSYNEKPRSRSLMDDDAFGPQGGSIVSAFDAFPKAKPQYVTQTSGGGKWTVFMSIVSVLLMFSETARWWRGAETHTFSVEKGIGHALQINLDTVVHMQCADIHINVQDSAGDWIHAAQALRSEPTLWSQWVDERGVHKLGYDAHGRIITGHGYEADEEGFGEEHVHDIVRHSRKKAKWARTPRLRGSTGDSCRIFGSMLLNKVQGDFHITARGHGYQSMGEHVDHRSFNFSHIISELSFGPFHPSLANPLDRTINMADDRFHKFQYFLSVVPTEYRIGDSHSQSLSTNQYAVTEQSREVNEMFAIPGIFVKYDIAPLLLQVVENRDSFLTFLVKIINVVSGVLVAGHWGFRITDWTREVIGRRRRSSMSYGVLGNKEMTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0G8</accession>
    <name>A0ABR3Z0G8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">26S proteasome regulatory subunit RPN2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RPN2</name>
        <name evidence="8" type="ORF">Cpir12675_003980</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the proteasome subunit S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000104">
        <property type="protein sequence ID" value="KAL1893682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016642">
        <property type="entry name" value="26S_Psome_Rpn2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002015">
        <property type="entry name" value="Proteasome/cyclosome_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048570">
        <property type="entry name" value="PSMD1_RPN2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040623">
        <property type="entry name" value="RPN2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10943">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10943:SF2">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13646">
        <property type="entry name" value="HEAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01851">
        <property type="entry name" value="PC_rep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18004">
        <property type="entry name" value="RPN2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21505">
        <property type="entry name" value="RPN2_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015947">
        <property type="entry name" value="26S_Psome_Rpn2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 8" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="26S proteasome non-ATPase regulatory subunit 1/RPN2 N-terminal" evidence="7">
        <location>
            <begin position="10"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="26S proteasome non-ATPase regulatory subunit 1/RPN2 N-terminal" evidence="7">
        <location>
            <begin position="199"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="26S proteasome regulatory subunit RPN2 C-terminal" evidence="6">
        <location>
            <begin position="865"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="917"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1121"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="958"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="989"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1136"/>
            <end position="1149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR015947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF21505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1149" mass="125691" checksum="F8F72B6BB9302222" modified="2025-10-08" version="1">MLATMSASSAAKGILGFLHDEEPDLRVFALQTLNDDINTVWTEVASAVDQIETLYEDETFPERELAALVLAKAYYHLQAYNQSMNFALVAGDLFKLNSPGEFEETIISKCIDLWIAVSAHEHSVNKGPKSSKTSASFAFNEAGLTSPTTPFSHSNLPSKSLLSRASTENALLDPSFKLADVGPNGSVSMVQMPDPSTRRALQAVIERLFEVCLRQGKYRQVVGIAMEAKRLDVLGSVIRRAGKDQNQTRGKTISDNTHPAEDLIEYALGICLDVVQERSLRTELLRLILDLLNEIPSPDFFAIAKCVVYLDADEEATMMLRHLVEKGDREAVASAYQIAFDLYDNSTQEFLGKVLKCLPSGEPKKAKNDQEDDQESDALLQKEVHDDEENIPEDQAKIYCNIRSILDGSKTIKLNLEFLYRNNKSDSNILNKVRDSLESRNSIFHTALTFCNAFMNHGTTNDKFFRDNLDWLGKAVNWSKFTATAALGVIHRGNLSQSRKLLEPYLPRAVPNGSIYSQGGALYAYGLIHANHGADALEYLTTQFVDAEEEVIQHGGALGLGIAGMATGSDNILEKLKSVLYADSALNGEAVGLAMGLIMLGTGNERVIEDMIAYSHETSHEKTVRGLAIGIALIMYGRQEGADMVIEGLLADPNATLRYGGILAVAMAYCGTGSNKAVRKLLHTAVSDVNDDVRRVAVMSLGFILFRKPSSVPRMVELLSESYNPHVRYGSAMALGISCAGTGLDEAIDLLEPMLKDPSDFVRQGALIALSMIMVQQNETMNPKAATIRKAFKKVVSDRHEDAMTKFGAALALGIIDAGGRNCTIGLQTQTGNLNMAGIVGMAVFTQYWYWFPFTHFLSLSFSPTSIIGLDHDLEIPAFKFHCSARPSLFDYPPEQEVKAEEGPALVATAILSTTAQAKRRAQKKEKAQRSESMDLDSVPAAKTPGGDADDKMDIDDEKEKKLAEDETNSEDKGDKKEGDSSATASATDAKKRNEKEKAGFDMENMSRILPGQLKYISFPAGRYQPVKKPTGGPMLLVDTTPDEPKTLLEEKLKKAATEKAPLAPGRTDGDASILITRGGIIHEQEDSTFQEIQDLLRSAGGGNGTTSEPHRVQLVMLADGNDQEEAPLPEPFDYFTDDEGDEAEEESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0H2</accession>
    <name>A0ABR3Z0H2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_003814</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000096">
        <property type="protein sequence ID" value="KAL1894126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038753">
        <property type="entry name" value="NFKBIL1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15263">
        <property type="entry name" value="I-KAPPA-B-LIKE PROTEIN IKBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15263:SF1">
        <property type="entry name" value="NF-KAPPA-B INHIBITOR-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="227"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="45"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="89"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="119"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="227"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1894126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="310" mass="36808" checksum="7A022EF6D51A307B" modified="2025-10-08" version="1">MDQSLSPKRRHILSSFNQEVDPARRLPADHKHYKPKHNSTSTQDHSTDRQRLRRRYSSEQDKHRCSSGPQEDRQPPDDGTKPHTKKLRLKGEGSRRRQRRRHEDEEKDIKHRDHDQHRQYRNSHRHRRRRHSRSPTPENPHQEPSLDPDAAFRESLFDALADDEGAAYWEYVYGQPLHVYGDPRQHNSSNIPEGTGSGLESMTDEEYAAWVREQMWAKTHQGLLEERTRRDAAHAEQAARRQDDAKRRREDRKLQREVERSLQAGEERRRRRTRREAWQRYLGAWSRWDGSVDTIPWPGGAQPLAGEEAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0T4</accession>
    <name>A0ABR3Z0T4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Translin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">tsn1</name>
        <name evidence="8" type="ORF">Cpir12675_003811</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the translin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000096">
        <property type="protein sequence ID" value="KAL1894123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14819">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.190">
        <property type="entry name" value="Translin, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.200">
        <property type="entry name" value="Translin, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033956">
        <property type="entry name" value="Translin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016069">
        <property type="entry name" value="Translin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002848">
        <property type="entry name" value="Translin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016068">
        <property type="entry name" value="Translin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036081">
        <property type="entry name" value="Translin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10741">
        <property type="entry name" value="TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01997">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74784">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1894123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="252" mass="27753" checksum="C9CA0387FAA452FB" modified="2025-10-08" version="1">MSSQTGLLASTIFDDLKARVETDSQTRDDIAQAVQKINASNAFSTGLLTRVHSTPRAKYPELLTQVEAGIKKDIVNIKELAALASEHPYYKFNFLWNRAIENVIFSILMAGFLGGVATETSAGELGRILTPEQVSEVLQVPYNVKNRDTFHITIEEYLLAVTRLTEELSRLVTNSVTLGDTALAVQAGQVVKDLFAGFQMLNLKNDIIRKRSDAVKYHVKKVEDVIYDLSLRGLLPRAGSGADAVVLDADQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1T9</accession>
    <name>A0ABR3Z1T9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutaredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003624</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000089">
        <property type="protein sequence ID" value="KAL1894498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03419">
        <property type="entry name" value="GRX_GRXh_1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011899">
        <property type="entry name" value="Glutaredoxin_euk/vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014025">
        <property type="entry name" value="Glutaredoxin_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02180">
        <property type="entry name" value="GRX_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694">
        <property type="entry name" value="GLUTAREDOXIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694:SF5">
        <property type="entry name" value="GLUTAREDOXIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00160">
        <property type="entry name" value="GLUTAREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="1">
        <location>
            <begin position="17"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="106" mass="11586" checksum="F43CB4AF035D1B01" modified="2025-10-08" version="1">MADAKETVQKLIEGEPVVMFSKSYCPYCSASKNLLNKLGYEFKVYELDKMANGSDIQDALEVVTGQRSVPNNFINGESIGGNSDLQSLHSSNKLEGLLIKAKAVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z367</accession>
    <name>A0ABR3Z367_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase I-specific transcription initiation factor RRN6-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003547</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000086">
        <property type="protein sequence ID" value="KAL1894656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019350">
        <property type="entry name" value="RNA_pol_I-sp_TIF_RRN6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048535">
        <property type="entry name" value="RRN6_beta-prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048536">
        <property type="entry name" value="Rrn6_K-rich"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28221">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28221:SF2">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10214">
        <property type="entry name" value="Rrn6_beta-prop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20639">
        <property type="entry name" value="Rrn6_K-rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRN6 beta-propeller" evidence="2">
        <location>
            <begin position="131"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="RRN6 K-rich C-terminal" evidence="3">
        <location>
            <begin position="943"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="870"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1001"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1068"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="876"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1002"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1075"/>
            <end position="1087"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1087" mass="121006" checksum="F6C742EF1924F614" modified="2025-10-08" version="1">MADTRDMGSLKYGYTGNIIYIPKKKSSSFATSAASETSVGELHASRRIDNSAPSFRIKSRWELCYTSSSSSIQPPDLPDEPPSTFSAKRVQKRWLQTAHPQTFAGISALSEILDEETRPSTPDQICVSDNTCFEIGEIADVTTRSRSRGAVPVVAKTSGSGGEILHIIRLQDMWFQWKDSKDISIRLRNMSLLDKQEEVFWSQDAVPITAIKFAVDRGLKRHRRWIMVQKRTGTTILQPEHHSVPVPVVNTGGGIAGMASRIDPRPLFTVASTQTGGHAHSDMAFTPTRGDQKARLAIIDEMGYWSVWSIHGSANIARNTVNVSMQVCGHIGRGILTNLLDPIPFPAQKHGIILCRIDRQDAFFDTSSAVRNGTHGLPATQTPIIFIWNSKQIAAFDIDTAEPVEPIPSIPPLRQSSETIIDAQIDPVSENRIVVLTSRHIFWVEFFCNAKTGTQRARILTSASHCTYLNDNDVQMTTSSFVESKDMETTLVMLHSLQTKTVKSFWLRNVEEIGLVQLYQSVSMVDSKDDQDRSAESIASAGILRLVNCPWGERDDVPFLDQAGKTSYLKASQDRELDLTASGFMFREKNTQFRQLFSLSRTGQIGYWICAIAPRADVAAITAPDVNVYAQANHWSKIIKKRKQAYVDFITPAFVIPDGLGNFEELAMRPLKQRSQENNPNDSLDNISNSKRLKRKFFLGWLQAQKYLRAAGAGPESRDKNLSIVSERIFAVVRDGVRYNRLPYRTLIECINAEELLETHAVENDQSWSSEIIQSCDFGHESPIITAIATRPTSGHVDLSAQLDGLRSEIAQKWPMPKSIASRADISLFRQRLIASIARDVVLATNAIFIRDLAPPGRLFQEELSSSQSNFVDSSQAQGSSPPRFMSHTQVPSENNTSQKYSQKESTTSINERKARGREAIHRLSQYAISIEIKGDLQETAPHQILGSWPKELGVSTDKYISSQAMVHVQREEEIRKKHQAIQAKRRRQALKYGIISEDSLRSSQTVGSPSSQAQTQNHIQSPAAPRINTPVVAPSTQVKVPAFTQPSSQPYGKSQIVMSQPVAGVFGGRDALKLQKRKKKKKGGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3N5</accession>
    <name>A0ABR3Z3N5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">chitinase</fullName>
            <ecNumber evidence="3">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Cpir12675_003497</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the glycosyl hydrolase 16 family. CRH1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000084">
        <property type="protein sequence ID" value="KAL1894802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02183">
        <property type="entry name" value="GH16_fungal_CRH1_transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF27">
        <property type="entry name" value="GLYCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045595485" description="chitinase" evidence="15">
        <location>
            <begin position="17"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="16">
        <location>
            <begin position="39"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="334"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="427"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="479"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="514"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="594"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="523"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1894802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="644" mass="67528" checksum="448C68B27BF8B111" modified="2025-10-08" version="1">MASRYLVALLASIAAAQVTTDCNPMQKSCPNDLALGTTHEWNFTTQPDTSIWKSKVNGVTFDPKLGAKFTVAKQGDAPTLMSNFYFFWGRTEMMLRCAAGTGIISSMMWLSDNLDEVDFEFLGTKPNQAASNFFGKGIENFANGGTHDVAFDNQADFHNYTVDWTADYLKWYIDGALIRTLSPNEANSSYSFPQTPMRFYIGIWAGGDPRLPQGTRDWAGGDTDYNAGPYDMYVKSVKITDYSNNSKEYQWSDRSGASSSIKIIDGTSSVAAALNKAPEKSLSEKFNDLSSGAKAGIFGGASFIGVAVVAAGLLYFFRQRKRGAAEAAAAEKAAEESRRENESMAARGINPDSFNGSTGAELNQLTQQDSNYVTNSMPNTPVNPHGPLDSYGAPTMSGMPGSTMAVGAGAAAGAGMAAGGAYAARSISRKPPPGGDPFNERYASPAPSGMSTNNHMYQNSGMGSPSPYNNAGYGANPHSPIGGISHHNGAPLSNSGMASPSPYDNVGYGANPHSPIGGISHHNGAQLSNSGMASPSPYDNVGYGANPHSPTGGIPQHSGAPISNAGFGGPGGYERVASPASNVGYGHQNYGNYAPDPSSPYSEGYLSSVPPAYSGGYGQTADGSIPLQNRKPTLPHMGNGGGFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4E1</accession>
    <name>A0ABR3Z4E1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003379</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000079">
        <property type="protein sequence ID" value="KAL1895107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="102" mass="11566" checksum="BE68FD46C2F07A82" modified="2025-10-08" version="1">MDDYDEETSDNGSHGPAASGSTTGHEDEEQDAVSDDEDCNSSDNQQLLSSARLKAARWQEEYLKANSQKLHLPEHERGLSYWGRLFRQNADQARRRNEGRAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z568</accession>
    <name>A0ABR3Z568_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PRKR-interacting protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003264</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000074">
        <property type="protein sequence ID" value="KAL1895357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009548">
        <property type="entry name" value="Prkrip1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13507">
        <property type="entry name" value="PRKR-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13507:SF0">
        <property type="entry name" value="PRKR-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06658">
        <property type="entry name" value="DUF1168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="232" mass="25333" checksum="1B24BC58581B6CBB" modified="2025-10-08" version="1">MSAGGPDSIPTSADRRSKRPTKRRLLSPTSDQAVSVEALFAKPEQPLHIPIAATPQARALPPPPEIVTNVQGSSAGAGSGEFHVYKAARRREYERLRRMDEEVRNEDADREFEQQKTERQKIDDEKTRKNREKREKMKVRKAKAKSGGGPQPKQSAKSTLPSQKDNKSSFSKRADIVDDTHEADNAPNDTPTTAESSGSARAEARDTKGASPAGTSTPDKAPITGLIIHDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5F2</accession>
    <name>A0ABR3Z5F2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003307</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000076">
        <property type="protein sequence ID" value="KAL1895290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039258">
        <property type="entry name" value="ZNF511"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21354">
        <property type="entry name" value="ZINC FINGER PROTEIN 511"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21354:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN 511"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="272" mass="30431" checksum="719E68F5D7575ACF" modified="2025-10-08" version="1">MKRSRDLEEDSSHCSDQEVIAALYPVSKAVQLDSELLDPKGGSCPVSNMICCLPPHKDPVSFRSFHDYEAHYARDHSYRCYECHRNLPSEHLLDVHIEECHDAFTAVKRERGEKTVKSCERKCSTPQKRRMHLIDKHLYPKNFFFAVTRDGIDGRNSLLHEGSYYRRRSSPGPAIATATTSSANHIHIAETPTLNQPAISSSSRNKPQDRLQAAASSSTKSNDGSTSDTIYQSAPTTPDTEMEDLADAMSGLKFVPRNIRFGRGCRAGFSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5G6</accession>
    <name>A0ABR3Z5G6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Ornithine aminotransferase</fullName>
            <ecNumber evidence="4 9">2.6.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CAR2</name>
        <name evidence="10" type="ORF">Cpir12675_003322</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 2-oxocarboxylate + L-ornithine = L-glutamate 5-semialdehyde + an L-alpha-amino acid</text>
            <dbReference type="Rhea" id="RHEA:13877"/>
            <dbReference type="ChEBI" id="CHEBI:35179"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:59869"/>
            <dbReference type="EC" id="2.6.1.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-ornithine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.13" evidence="4 9"/>
    <dbReference type="EMBL" id="JAWDJO010000076">
        <property type="protein sequence ID" value="KAL1895305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004587">
        <property type="term" value="F:ornithine aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050103">
        <property type="entry name" value="Class-III_PLP-dep_AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010164">
        <property type="entry name" value="Orn_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01885">
        <property type="entry name" value="Orn_aminotrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986">
        <property type="entry name" value="AMINOTRANSFERASE CLASS III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986:SF18">
        <property type="entry name" value="ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 10" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9 10" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1895305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="432" mass="46676" checksum="42DA371C7C30A4F2" modified="2025-10-08" version="1">MSSASRFHYASTEAAIAAENEYAAHNYSPLPVVFARAQGVDVYDPEGRHYLDFLSAYSAVNQGHCHPELVKTMIQQAGTATLSSRAFHNDVFPRWAEYVKNLFGFEMVLPMNTGAEAVETAIKLARKWAYKVKGVEQGKALVFGIDGNFHGRTMAAITLSMDPESRDNYGPFVPGIGASNPKTGAPLRYNNVEDVENLLADFGNETAAIIVEPIQGEAGVVVPDSDYLSRLHATCRKHNVLLICDEIQTGIGRTGRMLCHEWSGVKPDIVTLGKAISGGMYPVSCVLSSKAVMSVIEPGTHGSTYGGNPLGCAISIRALELVTEENMVSRAESLGKVFRDGIMAFKNPAVKLVRGMGLLNAVVIDEDKTNGRSAWDLCMLLKEKGLLAKPTHGNIIRFAPPLVITDEQLNTALAKIGEALTELPNAKQYGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z643</accession>
    <name>A0ABR3Z643_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">intramembrane prenyl-peptidase Rce1</fullName>
            <ecNumber evidence="10">3.4.26.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">RCE1</name>
        <name evidence="13" type="ORF">Cpir12675_003142</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>Hydrolyzes the peptide bond -P2-(S-farnesyl or geranylgeranyl)C-P1'-P2'-P3'-COOH where P1' and P2' are amino acids with aliphatic sidechains and P3' is any C-terminal residue.</text>
            <dbReference type="EC" id="3.4.26.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase U48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.26.1" evidence="10"/>
    <dbReference type="EMBL" id="JAWDJO010000069">
        <property type="protein sequence ID" value="KAL1895751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039731">
        <property type="entry name" value="Rce1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1/LyrA-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13046:SF0">
        <property type="entry name" value="CAAX PRENYL PROTEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13046">
        <property type="entry name" value="PROTEASE U48 CAAX PRENYL PROTEASE RCE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 13" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="154"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="CAAX prenyl protease 2/Lysostaphin resistance protein A-like" evidence="12">
        <location>
            <begin position="137"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1895751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="299" mass="33217" checksum="B836482BAC4F8887" modified="2025-10-08" version="1">MLPMGMTPELASGLLILYTIAYVAPLYASKTTRPSQTLNRDHPQVIRGRIAAVTISTIACNISSYIIISKASPNGHSDALALMGYWPLGITETIRTLLLNSILFAGPIFETLIIDGEWRALIDGSVVSSVWTNLHNWRNLVVGPITEEALFRSAAVPLFIIAGVSPGRTIFVTPVLFGLAHVHHFYEFRITHPKVPVSMALIRSFVQFAYTSVFGALATFFFLRTQSLLAVALLHAQCNALGLPRFWGSVSPYWVSYDVPSTSPVIRFWTMVYYMILLAGAITWYTYLWPLSFSPHGIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z674</accession>
    <name>A0ABR3Z674_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">BUB3-interacting and GLEBS motif-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_002959</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000063">
        <property type="protein sequence ID" value="KAL1896043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20908">
        <property type="entry name" value="SUF4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003656">
        <property type="entry name" value="Znf_BED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23215:SF0">
        <property type="entry name" value="BUB3-INTERACTING AND GLEBS MOTIF-CONTAINING PROTEIN ZNF207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23215">
        <property type="entry name" value="ZINC FINGER PROTEIN 207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50808">
        <property type="entry name" value="ZF_BED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="BED-type" evidence="8">
        <location>
            <begin position="13"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1896043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="309" mass="34287" checksum="38E577660F21B675" modified="2025-10-08" version="1">MGKKKRSFPDVEEILARPWCYYCERDFEDLKLLISHQKAKHFKCERCGRRLNTAGGLAVHLSQVHKETLTEVDHALPNRQGLEVEIFGMEGIPQDILEQHKTRIVQNFYQAQEDRRIATGNPLPGDGKHPPRKKIKMETPEELMARLHQYVAQRKADKAAGITHTDQPKQLPQTLPPQIVPGQYPLQYPPPIPGQAPGFSGYSGVATGLPTRPSQPNFWSPPPGVHVAPGAVGYPAAPHANDDIDDLIRSAETNAQSVQAAMAATPTEPAAVEKKKKDKGVRMIYSDTEVSPEEKMALLQRYAFVSAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6U1</accession>
    <name>A0ABR3Z6U1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Anaphase-promoting complex subunit cdc27</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CDC27</name>
        <name evidence="5" type="ORF">Cpir12675_003181</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the APC3/CDC27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000071">
        <property type="protein sequence ID" value="KAL1895543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558">
        <property type="entry name" value="CELL DIVISION CYCLE 16,23,27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558:SF13">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 27 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12895">
        <property type="entry name" value="ANAPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="127"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="594"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="628"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="662"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="764"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="192"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="265"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="353"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="397"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="200"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="397"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="819" mass="91415" checksum="D33260122D79B6D3" modified="2025-10-08" version="1">MAPSNTAISGCLRQVVYYHLDNFSYENALFFAEKLSAQDPRSPDSSYLLALAHYHNADFRSAYEVSRSHAARGTNICSAWIFAQSCLQLERWRDGINALEKIRNVVVQRNSIGQHSASIRAPHPDTSSVLCLLGKLYRGYDDKKKAVYCFEESLKVNPMQWDAFTALCDMGVNVRVQNIFRMSDTLIQSFDPNVDDSKPSDNVLTRKNTKSLVSDSHDPFETGIRPPDSSFGVYQSENGTSDFLSKIAAARSKLGVSSSNTIAVSNSEGLETPPNSNGSSNNSRAPYLDAPSVAGRRLRERNADLGGTEAPSKMMYRLGATKRTTRSQDKAEQPIEVFEAPLAPVSSRYATTVAERKRTVSGHPVRPPSAAANHSDDPPAAPQRRSARLNMFRPTASKANSSLTSGANATRELKKPRPTISRLIRPDGTGASVGRVVSGNRKPIEENMMDVEMTEGSRGAKDKESAPTVAPKATTEVDTLKIEESLKWLLELLRKIATGYSELAQFRPPEAVHAFQTVPKVQQETPWVLSHLGKAQLEQSAFIEAEKCFRKLRSIAPTRLKDMELYSTILWQLKRETDLSFLAHELIDVAWHSPEAWCSLGNAWSLSQDHEQALRCFKRATQLNPKFAYAFTLQGHEHMDNEEYEKALTAYRQAIAADRRHYKAYFGIGQVYRKLGNFERAFMHYQIAANINPSNPVLLCAIGTALEKQKNAAEALIYYSKATELFPKATDTRYKKARALMTLGEMDAARRELLILKDQVPDEAPVHFLLGKLYRNINQKQLAVRHFTNALALDPKASLQIKEAIEAFEEDIQMDDSIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7W0</accession>
    <name>A0ABR3Z7W0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002716</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000055">
        <property type="protein sequence ID" value="KAL1896694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="485"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="730"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="489"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="512"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="777" mass="86358" checksum="C5DC4415ACBD8A19" modified="2025-10-08" version="1">MELHVNLTAAQLEQIANAVNKLRMTEENKKSNGFVRGNSRSRFPLCGNGEGELKTPPRRAAYESTSSSLSPLSNLNRLLDNTNKTKSHNQKNQSAHVAASDKSSHARSSTRPPPIKLGDLDLGKYHPVSDYNEGQSHEKSESDYEDWTGYEDMSKYEAETGYEDISRYKDGYDSDSSDFEQSSRVPLEITQPSITISPRCLYTIPEAVGQESDAGHAGTSENRPSSRQAMSSPVTLAERRLRTPLSHLDLASGETVRQSSSHKVISTVPRSPILSLAADVSIINDESQELAKQALVDTPSSRYSQEIMSAKEYDVENHQETNILQGYTAWKASQDEQADQEDWVGQNAKRSEAETHPDNRSYYDISPDKPSSNQQHALQGGRGFTGLLSPRGGDKPLPYTPLTPFFNAEFKKDAALLGDNGWIEKIDEVDTQPPNISDIETFGANTDQALSRPMQQTTNQASFKPTIQSVSQPTVQPVPQADVPAASVAGNQNGGHSNIKASVTGMFSSPKSTEKTKTADTNQREFQKEDTGDKNEGKKKGFFGGLRKIARSMHDLTATKRPERTAHYSSMNISLDPREQSLLYCELEYHLTSAVHGYITTQFNHGRLDANKLKRVSDTWVTKGRPRVVGFRYDLETQLELVAMHDAEFRFYGRRQKNLLEIGALLYAMRTNARAMQVRTFCQPDSVVAKQLVDSQSLFNMMGVPQMQQIALQQIGQFFRAIVERESRKRKEAERAGMQTPMVGPGPASKFPVGGEIRSDMPSVYSTPEMESDLSKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8P4</accession>
    <name>A0ABR3Z8P4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Reticulon-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_002592</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Endoplasmic reticulum membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000052">
        <property type="protein sequence ID" value="KAL1896943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003388">
        <property type="entry name" value="Reticulon"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02453">
        <property type="entry name" value="Reticulon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50845">
        <property type="entry name" value="RETICULON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Reticulon" evidence="8">
        <location>
            <begin position="19"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="238"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1896943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="258" mass="28649" checksum="6403A0F56A7B19A5" modified="2025-10-08" version="1">MADAKIAPKPAGENFSSYFQYLLSWNNPRDSGIAYGSIVAGIILIRCIDVLRYAFKLTYLTLAVTVAAEVLGKLVIGNGLTSQMRPRKYWTISRDATEAMASDLHELANFISTEFQKIVYVENTYVSGAALIGAFLSYHLVKIIPYWALAIMTVSAVFFGPLVYRENQEVIDAQIDKLYELLAEKNIELRKTAVDLTGQAGDMAKQHFGNFSTKAQSMLRGRVEKIKIDDFPAAPTGELKKEAEKEEVKVPEAEPLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z991</accession>
    <name>A0ABR3Z991_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">mitochondrial processing peptidase</fullName>
            <ecNumber evidence="5">3.4.24.64</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Beta-MPP</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">MAS1</name>
        <name evidence="17" type="ORF">Cpir12675_002408</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins. Preferentially, cleaves after an arginine at position P2.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of N-terminal transit peptides from precursor proteins imported into the mitochondrion, typically with Arg in position P2.</text>
            <dbReference type="EC" id="3.4.24.64"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the peptidase M16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.64" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000047">
        <property type="protein sequence ID" value="KAL1897226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050361">
        <property type="entry name" value="MPP/UQCRC_Complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001431">
        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851:SF149">
        <property type="entry name" value="GH01077P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851">
        <property type="entry name" value="METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00143">
        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="15">
        <location>
            <begin position="54"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="16">
        <location>
            <begin position="206"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1897226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="476" mass="52602" checksum="F788189BDA96F703" modified="2025-10-08" version="1">MASRRLALNLTSGLRSRASPSLSQSLRRGLASPAATGSVFGKTQTTTLKNGLTVATEHMPWLQTSTVGVWIDAGSRAETPETNGTAHFLEHLAFKGTAHRTQHQLELEIENMGGHLNAYTSRENTVYFAKAQNSDVPQCVDILADILQNSKLEEAAIERERDVILRESEEVEKQVEEVVFDHLHATAFQHQSLGQTILGPRQNIRDITRTELTNYIKKNYTADRMVLVGAGGIPHEKLVELAEKNFSGLPVSTPLTYAVEKPKADFIGSDVRIRDDTMPTANIALAVEGVSWSSPDYFTALVTQAIVGNYDKALGNAPHQGSKLSGFLHKNELANSFMSFSTSYSDTGLWGIYLVSDNTDNVDDLVHFTIREWMRLCTNVSQAEVERAKAQLKASILLSLDGTTAVAEDIGRQIITTGRRMSPAEMEKSIDSITDKDVMDFASRHLWDQDIAISAVGSIEALFDYQRLRNCMKPKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z999</accession>
    <name>A0ABR3Z999_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PRE8</name>
        <name evidence="5" type="ORF">Cpir12675_002636</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000053">
        <property type="protein sequence ID" value="KAL1896915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03750">
        <property type="entry name" value="proteasome_alpha_type_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="1 2 3" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="4">
        <location>
            <begin position="3"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1896915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="280" mass="30258" checksum="26A8741184C659C4" modified="2025-10-08" version="1">MAYNFSLTTFSPSGKLIQIEYALNAVNQGVTAVGIKATNGIVLASEKKSSSPLADPQSLAKITDITPNIGMVYAGMGPDYRVLVDRARKVSHTNYKRIYNEYPPTRILVQDVARVMQEATQSGGVRPYGVSLLVAGWDEGILPDEEVEAMAAGKATTSERKKPTGKTGGILKGGPMLYQVDPSGSYFPWKATAIGKSAPQAKTFLEKRYSEDLELEDAIHIALLTLKETIEGEMSGETIELAIVGPPADHLLGIEGVEGARGPRFRKLSPQEIDDYLTNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9N1</accession>
    <name>A0ABR3Z9N1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Calcium permeable stress-gated cation channel 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_002541</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CSC1 (TC 1.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000051">
        <property type="protein sequence ID" value="KAL1896962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032880">
        <property type="entry name" value="CSC1/OSCA1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF149">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11660)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13967">
        <property type="entry name" value="RSN1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="408"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="450"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="495"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="620"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="670"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like N-terminal transmembrane" evidence="10">
        <location>
            <begin position="49"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="11">
        <location>
            <begin position="221"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="9">
        <location>
            <begin position="402"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="957"/>
            <end position="1022"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1896962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1022" mass="114138" checksum="E12EB3B0369EDF60" modified="2025-10-08" version="1">MSISARTVSTVLRYLVARDDDDADQNLDAGQELLDLLKDPFSGDISSTSLWTAIAVSFGFTAFIAICFSLLRPYNQSVYAPKLKHADEKHAPPPLGKEPWSWFIPLWHTSEADVIAHVGLDAAIFIRFTKMLRNMFVFLGVCVCAIIIPMNLKNGTETQQRSWLSNIGPSAVWGKSNWADVAAAWVITFTIMFFLWFNYRKVTQLRRDYFNSHEYQHSLHARTLMLTDLPRDRCSDEGIARIIDNVAPSSSFARTAIGRNVRDLPTLIAEHERIVRKLEKVLAIYLKNPAQIPPSRPTCKPSKKDPSYSTYPKGQKVDAIEYLTQRIKNLEFQIREVRTTVDRRNTMTYGFASYSDIAEAHSIAYTTRGKKPSGSTIELAPRPEDLIWPNMPLSPSVRSWKGIIINMWIVFLTVVWVVPNAMIAIFLVNLSNLGRVWPAFKSELKAHPTFWGMFQGVANPALTSLIYLVLPIVFRRFAVMAGDRTKTGRERHVTSKLYAFFVFNNLIVFSLFSTIWAVIAGVVDDTSKGMDAWKAIIKNNPTSALLESLCGNSPFWVNWLLQRQLGAAIDLAQLWPLVYGFFMRKFSSPTPRELIELTAPPIFDYASYYSYFLFYSTVALFYAGIQPLVLPAAAIYFIIDGWLKKYLLLYVFITKNESGGLIWRVLYNRMIYSILLAQIIFLLIVWARGDTSREILAYCLAPLPVIVITFKIYCTKVFDSQMYYFSCENINKTQVIDPSKDSRLRSEKLASRFGHPSLYKPLITPMVHAKAQDMLHIVYSGRLSNGRDSVGVGGGGDFMSVSGYSDTFAMDAMKQGQPGKTTGVSGFELVSESQLDFQYYKNRPEFADGHGGGGVLYGNPSDIMRPDTPNSTFSDNSRPGTPTQIYGGMTGGTRPTLPTVNGPYSYAPYRSHTPVSNFTAPDHAFLGQPSLYAQNNDSSAGLISSAADMAVVAPARSVQGYDPRDHNREPSLPTVHVPGPSTGALGGGPQGYSGVPQAEAPEPIQYDYFRGGGQTRRPGDGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA35</accession>
    <name>A0ABR3ZA35_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SEC4</name>
        <name evidence="7" type="ORF">Cpir12675_002299</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000044">
        <property type="protein sequence ID" value="KAL1897511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01867">
        <property type="entry name" value="Rab8_Rab10_Rab13_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050305">
        <property type="entry name" value="Small_GTPase_Rab"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47980">
        <property type="entry name" value="LD44762P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1897511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="202" mass="22538" checksum="A9639BB679CEBE9B" modified="2025-10-08" version="1">MASNRNYDFLIKLLLIGDSGVGKSCCLLRFSEDSFTPSFITTIGIDFKIRTIELDGKRVKLQIWDTAGQERFRTITTAYYRGAMGILLIYDVTDERSFNNIRTWFNNVEQHATEGVNKILIGNKCDWEEKRVVSTERGQALADELGIPFLEVSAKSNINIDNAFYSLAADIKKRLVDNSKNEKESSGGVNVSESNAKGGGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAF1</accession>
    <name>A0ABR3ZAF1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Histidine biosynthesis trifunctional protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="19">Phosphoribosyl-AMP cyclohydrolase</fullName>
                <ecNumber evidence="19">3.5.4.19</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="19">Phosphoribosyl-ATP pyrophosphohydrolase</fullName>
                <ecNumber evidence="19">3.6.1.31</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="19">Histidinol dehydrogenase</fullName>
                <shortName evidence="19">HDH</shortName>
                <ecNumber evidence="19">1.1.1.23</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="22" type="primary">HIS4</name>
        <name evidence="22" type="ORF">Cpir12675_002409</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 19">
            <text>1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O = 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:20049"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="EC" id="3.5.4.19"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 19">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + H2O = 1-(5-phospho-beta-D-ribosyl)-5'-AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22828"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="3.6.1.31"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18 24">
            <text>L-histidinol + 2 NAD(+) + H2O = L-histidine + 2 NADH + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:20641"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 9/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 19">In the C-terminal section; belongs to the histidinol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.19" evidence="19"/>
    <dbReference type="EC" id="3.6.1.31" evidence="19"/>
    <dbReference type="EC" id="1.1.1.23" evidence="19"/>
    <dbReference type="EMBL" id="JAWDJO010000047">
        <property type="protein sequence ID" value="KAL1897227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06572">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11546">
        <property type="entry name" value="NTP-PPase_His4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1080">
        <property type="entry name" value="MazG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1980">
        <property type="entry name" value="Nitrogenase molybdenum iron protein domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.810">
        <property type="entry name" value="Phosphoribosyl-AMP cyclohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01024">
        <property type="entry name" value="HisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008179">
        <property type="entry name" value="HisE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016298">
        <property type="entry name" value="Histidine_synth_trifunct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001692">
        <property type="entry name" value="Histidinol_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012131">
        <property type="entry name" value="Hstdl_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021130">
        <property type="entry name" value="PRib-ATP_PPHydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002496">
        <property type="entry name" value="PRib_AMP_CycHydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038019">
        <property type="entry name" value="PRib_AMP_CycHydrolase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00069">
        <property type="entry name" value="hisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03188">
        <property type="entry name" value="histidine_hisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256:SF2">
        <property type="entry name" value="HISTIDINE BIOSYNTHESIS TRIFUNCTIONAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256">
        <property type="entry name" value="HISTIDINOL DEHYDROGENASE HDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00815">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01502">
        <property type="entry name" value="PRA-CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01503">
        <property type="entry name" value="PRA-PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001257">
        <property type="entry name" value="His_trifunctional"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00083">
        <property type="entry name" value="HOLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101386">
        <property type="entry name" value="all-alpha NTP pyrophosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141734">
        <property type="entry name" value="HisI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00611">
        <property type="entry name" value="HISOL_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 19" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="16 19" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="11 19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="15 19" id="KW-0520">NAD</keyword>
    <keyword evidence="10 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14 19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Phosphoribosyl-AMP cyclohydrolase" evidence="21">
        <location>
            <begin position="208"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="374"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="376"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00008260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRNR" id="PIRNR001257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF01502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAL1897227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="850" mass="90170" checksum="E7A0B7A12F393241" modified="2025-10-08" version="1">METVLPLPFVVGIPASASGQGLTESELSILGSVLYESASNIPKKALISKAFVNGIGLAYDDVATLLDQGIGAVFVPAANIAEFVEFGSRVLPIVESTGDITTSSLVSNFDAATVNAEALKAQIKAVKGPVFVRVSGSNAAELTAAIEVAKTTGAIAVLPSSSLTTAAGAEAGHKLPLERAFSLFWKSDRADGLLPTVVVDEHEVSLGLVYSSAASVNEAVKTAAGVYQSRKRGLWVKGLTSGDTQELVSISLDCDMDALKFVIRQKGRFCHLEQFGCFGELRGLSRLEATLKARKESAPSGSYTARLFSDEKLLRAKIMEEAEELCGATNSEEVSWEAADLFYFALTKAVASGVSLSDIERNLDSKSLKVKRRKGDAKGKWAEKEGITTSTPAAPAPTPVSAPAADERIVMKCIDASKVSATELTEALKRPAQRSPDAIVNIINPIIQDVKNNGDAAVLKYTRTFEKATSLESSYMKAPFAPELMGLPAETKAAIDLSFENIRKFHVAQKEEKPLQVETMPGVVCTRFVRPIETVGLYIPGGTAVLPSTALMLAVPAMVAGCERLVFATPPRPDGKPTPEVVYVAHKTNAEGIVLAGGAQAVAALAYGTESIPKVDKIVGPGNQFVTTAKMVISNDTNACVSIDMPAGPSEVLVIADNNAVPAFVASDLLSQAEHGKDSQVILIGVGLSPQRLQEIEDELHNQALALPRIDAVRGSISHSVTILVKDTEEAMRISNEYAPEHLILQVDDAEKLVDQVKNAGSVFIGQWTPESVGDYSAGVNHCLPTYGYARQYSGLNLASFVKHITSSNLSAEGLKNVGGAVMELAGVEELDAHKRAVGIRLDYINKNKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAP4</accession>
    <name>A0ABR3ZAP4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002513</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000049">
        <property type="protein sequence ID" value="KAL1897192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="119" mass="12955" checksum="0BF206B7366E3D0C" modified="2025-10-08" version="1">MDRSSTNTPTPSEASSTAGHRSETPSLFHPQVNSAGNPLPPLCREYPLPKEPVDVAEALARPPLRWTIKGTMAAGEHRQIRVKTDEEKTQEFAQAKADLVKASASLNNLPNIDRRSPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAT6</accession>
    <name>A0ABR3ZAT6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transmembrane 9 superfamily member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TMN2</name>
        <name evidence="8" type="ORF">Cpir12675_002602</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000052">
        <property type="protein sequence ID" value="KAL1896953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004240">
        <property type="entry name" value="EMP70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766:SF111">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02990">
        <property type="entry name" value="EMP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044970588" description="Transmembrane 9 superfamily member" evidence="7">
        <location>
            <begin position="26"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="344"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="377"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="410"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="444"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="504"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="534"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="573"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="612"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1896953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="643" mass="71534" checksum="CE0590389E2334DE" modified="2025-10-08" version="1">MRSPTLGSAAAAVASLLALTQSASAFYLPGVAPNSYKPGDAVPLYVNSITPSAAETDNLIHAVISYDYYSPMFGFCQPKDGVKDVPESLGSILMGDRIKNSPFELFIGKDEQCKQLCTSKYSTEHLKFLAHRIRQGYSLNWLVDSLPAAQELKDTASQTTFYSPGFYLGSVSKDGQIFMNNHYDIEVEYHEVANNPDQLRVVGVIIRPSSKKYSDGADCGSHHEPIVVAGGVHEVDVTFSYSVTWKKSATAWATRWDKYLHVFDPKIHWFWLIDIAIVVFILVMTVVSILVRTLRKDIARYNRLDQISLDDFGDPISMEDGVQEDSGWKLVHGDVFRPPSHPMLLSILVGSGVQIFGMTGLTIIFALLGFLSPSNRGSLGTVMILLYTVLGFVGGYVSARTYKAWNGEKWKVNIVLAPIVVPGVVFSAFFLMDLFLWASSSSGAVPFSTMLVLITIWFIISIPLSVTGSYMGFRAGQYQAPVKTNQIPRQIPSSTLYLQPIPSMLFVGLLPFGAIFVELFFIMSSIWFSRIYYMFGFLFLCYMLMIIICATATILMVYFVLCAENYNWQWRSFLAAGSMGCYIFVYCLLYLVSKVHVSSVAGAVLYLGYSSLLSLMFTVLAGSIGYLSSWWFVNKIYASLKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAX6</accession>
    <name>A0ABR3ZAX6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002178</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000039">
        <property type="protein sequence ID" value="KAL1897833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1897833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="414" mass="46640" checksum="6A8F4EE0678414D6" modified="2025-10-08" version="1">MDSQLWTRVDDRFEHSWKLRQTWKSLINAPTTELGTQSWIRNVMACWNEACKIQAPFVNPSSPIREFKESVGRMLDVYSTHTGGTSRLKELGEPTLEVIETCFQHSLRAEYKQACLELEVRKDNARCAHVKNSTSNTAIPFNGPEPEGDHSHACICGVSHAGGIPGCFYLVPELRPPTFIVREKVEQRIERVLAGDRRLNFYVDKARAKARNGNVTPLQTSFSAETSEVDLSPPHVEVVAGWTHGHYDNSTTIGSETSTQTDIVPSSTFTPVPARTYPAKPPAQLHPLHKSWVISASSTICVCNDISRLTNFEPAEPDEKIFAHGQEVGVLGVGKAELRIESYEDGYQYVTFPEVWLVPEYYTNVIALNALEGFDITWVHRDDVLVMKNEPWCKVKRINGMHVLDYTPLQKEIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC71</accession>
    <name>A0ABR3ZC71_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">NPR1</name>
        <name evidence="12" type="ORF">Cpir12675_001989</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000035">
        <property type="protein sequence ID" value="KAL1898283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343">
        <property type="entry name" value="SERINE/THREONINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343:SF137">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE HRK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="444"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="85"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="174"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="663"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="833"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="240"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="297"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="360"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="400"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="677"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="697"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="749"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="838"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="473"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1898283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="853" mass="93348" checksum="8DB91849CC8E4B25" modified="2025-10-08" version="1">MTLEHEVAHIEIESTSTNASRQTTLIAHDDPSSQYYSSAQNQQHHHNHSYSPDLAVPLVPPVPTVPSVRIASHDLETIPTTVVSPAVDDTAPDSAAETDTTIATPPTVSAANTKNTIMPPVATNSFQATITPPPPMPSSNRTLAEVDPNIQQLSKSLKEANLQKHHRMAFEPIASLPASRVPSHESIPMSPSQRTLDSYGPGTRTSMASINSPPLTPSGTDADSGSLGMTKRHAAGSRDSIITPQPSSSQDASPRNHQHETSGTPKSSADNLPLNTAEDNLRQNNHRRGMFSLGNGASASSSRESSPSRAASYYSRPFTPGGDSKNPYAASKRAPQPPVTSNPKNIEPRFQFSRKKKLGSPCTSSTSLLSPDKRHHHKDDHGHGDVSSTPKSSMVDLKRFFKKAHHHHKRDKSPAPKQKAQSPLKTGHSAVPFGEDHGLVTKYGKFGKILGSGAGGSVRVMKRSDDNTVFAVKEFRARHTYESEKEYAKKLTGEFCIGSTLRHGNVIETLDIIQERGRWFVVMEYAPFDLFAIVMTGKMTRPEVSCCFLQILNGVTYLHSMGLAHRDLKLDNVVVSANGIMKIIDFGSAHVFSYPFEEGIIKAKGIVGSDPYLAPEVYDDKLYDPRTVDIWSLGIIYCCMTLRRFPWKVPRLSDNSYKLYASEPTPGHDPNKLLLPTSPTASTAGNESGDYFSSNHGKQHHHNHHNHHNHHHHHHHHHSEDASVPGTPRSTPASPGPRDSRHGAKSPSAVESTSQNPVTPAAQPAEKKEVIKGPWRILRLLPKESRMVIHGMLTIDPAKRMTMDQIIADDWVANTVICQQLPNAEVIRANDHTHTLEPPLPPAQPQPKPPQAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCA3</accession>
    <name>A0ABR3ZCA3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">SEH-associated protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_002014</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat mio family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000035">
        <property type="protein sequence ID" value="KAL1898306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037593">
        <property type="entry name" value="MIOS/Sea4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049092">
        <property type="entry name" value="MIOS_a-sol"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031488">
        <property type="entry name" value="Zn_ribbon_mio"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16453:SF9">
        <property type="entry name" value="GATOR COMPLEX PROTEIN MIOS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16453">
        <property type="entry name" value="WD40 DOMAIN-CONTAINING PROTEIN MIO FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21719">
        <property type="entry name" value="MIOS_a-sol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17034">
        <property type="entry name" value="zinc_ribbon_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="MIOS-like alpha-solenoid" evidence="6">
        <location>
            <begin position="557"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="domain" description="GATOR2 complex protein MIO zinc-ribbon like" evidence="5">
        <location>
            <begin position="1022"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="927"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="986"/>
            <end position="996"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF21719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1109" mass="122380" checksum="4216975F6BE03227" modified="2025-10-08" version="1">MMDRMDSGLVKWCPHPAHESFMHINLQHRVVQVYKPTGRAKQGSFDYQPISKYEDIPPLTTYDWSHTSPGLLAVGTAAGVVNLLRVDDNSNDYVELGLKMVRVCQAVAFNLQCKLAVGLERVRMDQCLHIWDLGHLTRLDARISGFQKDHSAFAESAIKLEPSVSVSSIRFFDDHPDTLVVGIKGQGLRIHDLRGPTSVATFHTKCNNNLAIDHSDQNYFASSALDQPGIMIWDRRAANKPVQSATYARAVEDESVPYGAALKLDRIVDVDNEVSISDSMHSDIRSLRFCRDRRGMLGILSRTGQLKVLQTNKERISDQVDSGGSQSAELLEVYKSHDMDVSRFGSGRKNDRIVSFDWVSLQNPVLRPRMLVLRANGKFDILEQPSNASNHLFNLVPWKPPHRSLAEKEPYHDIMHFEPAQVSTMLGPLLVDQALSEIPIFGAQRANLVAIMAGAVQPKNASGAAITDVDAADRPLPSTFAEATTVAGKLKVLRDFAKEIATPSPKSLPTEKEKNKPRNSGLISCREIHEELLTILMRTKGLPREAHETIDHVMLLRAKEMYLFNAKRNAEVVTDDPWLRNLWEWIADAEVAAGDTDMGVHPLDLSYLGVYSIWKNDLGLKPSARITIGGSSDIDRGVWERHIGSLCKKRRLPRYDGIDTQWPNHRQICLSICTWGEGAPEGSDSFHDVLPEFPTTVHTRAAARALFRGNTQQAVDLLKHASSKHPELLFVSLALQLMGREERSMAKAQLDFDERVASKTDPYLRAISSLIATGDWRTIANQKSLPLADRTYVAVRNLKDAELTQWLESEVASAAETGDIEGVVLTGLSAKMIEILAKYVAKFGDYQTATLVCAIFAPRYVDDFRAHAWRTAYRAYLQRYKAFLQRTKYDVESTKLSKRDASSRPGLKPSGRQIALRCAFCDAQPGRREELRSPTIPSQHQHQHHHHGSGSGLGHRGVSSPAPSPALVHQTSASPPGLGGGGNGSGVMTPGPNKGPSVGGSGSSGGAPISNPLTAAAVAAGISCPQCGRNLPRCVVCLEIVGMPRSDRPETSADPAVRAAARFPSFCLRCEHVLHLDHARQWFARMSECPVPECKCQCNFRANAELMYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCI7</accession>
    <name>A0ABR3ZCI7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcription factor TFIIE beta subunit, TFIIEB, Tfa2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">tfa2</name>
        <name evidence="9" type="ORF">Cpir12675_002201</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000040">
        <property type="protein sequence ID" value="KAL1897776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054600">
        <property type="entry name" value="TFA2_E-tether"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040501">
        <property type="entry name" value="TFA2_Winged_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016656">
        <property type="entry name" value="TFIIE-bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003166">
        <property type="entry name" value="TFIIE_bsu_DNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12716:SF8">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12716">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIE, BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22254">
        <property type="entry name" value="TFA2_E-tether"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18121">
        <property type="entry name" value="TFA2_Winged_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02186">
        <property type="entry name" value="TFIIE_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51351">
        <property type="entry name" value="TFIIE_BETA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TFIIE beta" evidence="8">
        <location>
            <begin position="78"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="26"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="26"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1897776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="343" mass="37986" checksum="EEDF2C2D8EAC7A01" modified="2025-10-08" version="1">MPATYTPRLSKSGLGASAIEAASKMSKSSSLKNLNAASNTSTRAVSPAPSAAGSRSDLTSTPTKRKRDAPGTVYSQPDITGFGNDLMTQMTFAVEFLKGKDNRMPVQDILAYLSLTRFSEDHQKELVQTMRRHPRIEFFPDPNLTEQTWKSGTYAHRPLIPGVRDKISLLQYLQKRTDAQGVQVRELKDGWPDCEPALTELEKERKILVCRTKKDNVPRQVFLDDTSLFHHIDSDFQKMWLTTIIPKVDELPRKLMAVGQRPTSDDSLAIKTVAPKGKAQKKRAVRKVGKATNEHMEALLRENGHFLPGMATTTPATGTTGSNGHGHGHGYGHGHGHGYGYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDB2</accession>
    <name>A0ABR3ZDB2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">TM7S3/TM198-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_002340</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000045">
        <property type="protein sequence ID" value="KAL1897484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025256">
        <property type="entry name" value="TM7S3/TM198-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39469">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39469:SF1">
        <property type="entry name" value="DUF4203 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13886">
        <property type="entry name" value="TM7S3_TM198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046303050" description="TM7S3/TM198-like domain-containing protein" evidence="7">
        <location>
            <begin position="25"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="233"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="312"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="TM7S3/TM198-like" evidence="8">
        <location>
            <begin position="127"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="377"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="444"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="547"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="704"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="796"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="377"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="444"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="478"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="552"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="603"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="796"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="837"/>
            <end position="861"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1897484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="936" mass="101945" checksum="92B0A4B64F270477" modified="2025-10-08" version="1">MLPRSVSILISLLSVLLLSHDVAAHLLRRQQVDLVDPISTHSVIQTTSTSKLNFSETPTVTASDFSFLPTTTPHATITSAPFNLTNSTVGRNSTATHNSTATSTATTAPYPALPIKVRLTPAFAIAGALLIISGGVLAFWNNKSIQAFIGGAMLAALATIVLIVYVMNPPISKGLQCAYLVAGLVTGLALGGMSLLFREIIESLTCLLCGFCIGMWFLCLGDDGLIHVTAGRVALIAGCSFVAWSIYWIPFTRDWTLMALTSFAGATVVILGVDCYSRAGLKELWVYLWDIHADLFEYNMTFNITKGIRAELAAIIVLWGAGIVAQAHLWRKIYSRKNAKRAEKKAARADVEALNEAAGRAMQTQLAHEKANWERTYADSNSIHEVDGDDKSKSRRSSEDSGVHGIAAVDYSQSGRYSNHRHGGFSASEYGAAKNGIPQRHISTITNAPRNSNPYPGSQPLSTPRRSSTKRVSSYSSTHTKSVPISPVASQPQISPGRSSFHTSVNSPTKSHHEILIEEPEYLAQDGASQEFGSNRDESLSLVATVDDAQSRRSLATNHGSSSSNKTESHQHSQNDANHIESLVSGHNSCKSTSNREDEKECASSQTSTVSSVEKVALPGKISQAALKSRTNDWVRQSIGADHPDLENIKTNGDSDVCVSEEAARPVNVQDLQLAAGDVSIPTTGVSQTLADFYGPSIAVVNAHHEKHRTSRKSAGQESNKQRSSGRRASAGNSQTLLDRRDGYLRTKHQLAQVPQSALSLRASDSRIISRRQSARNAMDESTGQLQRQNLTMSNLIIPSNNQNPNSHRRPVLSPKRRESQLASFRESMQADPGVRSSLSPTNMGPTSSPTLSPGLKPSSSLAHMGSHLCYRPEDEQILERQRSLLLDKMEADRTTRENELRNRELADQRLEQMMNFGGMQSTHREMLRRMQDKAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDB4</accession>
    <name>A0ABR3ZDB4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">leucine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Leucyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">CDC60</name>
        <name evidence="13" type="ORF">Cpir12675_001778</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Leu) + L-leucine + ATP = L-leucyl-tRNA(Leu) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11688"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000030">
        <property type="protein sequence ID" value="KAL1898671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="entry name" value="Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004493">
        <property type="entry name" value="Leu-tRNA-synth_Ia_arc/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055416">
        <property type="entry name" value="RBD_LARS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00395">
        <property type="entry name" value="leuS_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45794:SF1">
        <property type="entry name" value="LEUCINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45794">
        <property type="entry name" value="LEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24810">
        <property type="entry name" value="RBD_LARS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="10">
        <location>
            <begin position="64"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="10">
        <location>
            <begin position="206"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="11">
        <location>
            <begin position="834"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="domain" description="Leucine--tRNA ligase RagD-binding" evidence="12">
        <location>
            <begin position="985"/>
            <end position="1049"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF24810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1898671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1118" mass="126029" checksum="5E74624D9587A733" modified="2025-10-08" version="1">MAAPTAAIDGLAISKTKELKGTEKRDKLVSWEKQCQAKWAEEKVFESNPPSIDEIPLDAMSSEELREKHPKFFGCMAYPYMNGNLHAGHAFSISKVEFTGMVASMQGKRALTPLGFHVSGMPIKACADKLVNEIRMFGKDFSGYNPEAESETAPAPAAAPRVREDITKFSTKKSKSVAKTAKMKYQFQIMAASGVPLQEVHKFADVNHWLEFFPPIARRDLTAFGSRADWRRSFVTTTANPYYDSMVRWQMTRLKELGKIKFGNRYTIYSIKDGQPCLDHDRQSGEGINSQEYTGLKMRVVEWAPKAQEALKDKLPTDAKVFLVAATLRPETMYGQTNCFVGPEITYGVFKASPTDYYVVTSRAAKNMAYQGLFEKNGEVVKVADLPGPAIIGTLIDAPLSQYGQVYVLPMATVKEGKGTGVVTSVPSDSPDDYINVMDLKKKPEFYGIKAEWIDKDIIPVIETPAYGKACAETLCKQMKISSPKDTVQLEKAKELAYKAGFYNGTMIVGEFAGDKVEEAKPKVREQMIRAGDAFVYAEPEGKVMSRSGDECIVALMDQWFLDYGEETWRDQALEWVENKDGNGINTYSSEAKNQFQAVLGWLNAWAVSRSFGLGSRLPWDESQLVESLSDSTIYMAYYTLVPFLHKDIFGKETTEYNIKPEQMTMNVWDYVFCRTEWSDEVEKTSGIPRKTLESMRRSFQYYYPLDMRTSGKDLIGNHLTFFIYNHIALFPQEYWPKGIRTNGHLMVNSEKMSKSTGNFMTLHDLVGKYGADASRIALADAGDGIGDANFEEDVADNNILRLYNCREWCEEIAKTKQENKDEFRSGKLNDFQDKLFNNDINAIGREILHFYDQTNYKLALKCIYEFFNARDFYREACTAAGIPLHQDLVECWIRNLALLINPLAPHFAEFLWIEILKESGSIQTQRFPDLPEADVSLTAAREYIKNISSAVNSAESTQLKKKAKGKEVSFDPSKPKKLTIFINTKFPEWQQKYVDLLSEMWDPATRSLDEKALMGRVSKMGEMKKAMPFTQTIKKRLQAGEDALNRTLLFDEADILVKTIPSLKRSAGLKEVDIVRVLEGGKKGKRVMDGAEVDIGVPSAENAVPGNPSYNFENVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDD5</accession>
    <name>A0ABR3ZDD5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002084</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000037">
        <property type="protein sequence ID" value="KAL1898065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="405" mass="43740" checksum="CB3D9254912EB4DC" modified="2025-10-08" version="1">MQRSAPLTIRATVGLARPLAASLASIPVSQWACRGISQAFVARRQWTVGSVSQSCYISSAATEAPVSASSSSNLSKLLSIIERTEAMFLARKDVPCEPVIMTALRACHTAAKAITSANAETGKQPGNSLLQVDDKLAKAPSHKSTFAELRKNTMLKISQAAFNIISAPNVVVTMPLLKQYIQIHAELGLANTVAEALAMYGSKPVPVESANGVISFKKRYPKLPSAAIDEDVAAAALQVALQAKNLDAAVNIVDVCYCSQAFYLRKIMASATMPALAAGLIPTTSYGIASAFANYNSSIDPGMATSFAFMGIMAYIGFTGSMGFVARMSMMDHMNRVTWMPGTPMRKRWLREDERAAMDKIATAWGFLESWKHGEESGPEWASLREYLGLKDMILDRVEFMEGMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFK2</accession>
    <name>A0ABR3ZFK2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Substrate-specific activator of APC-dependent proteolysis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CDH1</name>
        <name evidence="8" type="ORF">Cpir12675_001702</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat CDC20/Fizzy family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000028">
        <property type="protein sequence ID" value="KAL1898949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033010">
        <property type="entry name" value="Cdc20/Fizzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056150">
        <property type="entry name" value="WD40_CDC20-Fz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918">
        <property type="entry name" value="CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918:SF1">
        <property type="entry name" value="FIZZY-RELATED PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24807">
        <property type="entry name" value="WD40_CDC20-Fz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CDC20/Fizzy WD40" evidence="7">
        <location>
            <begin position="233"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="277"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="360"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="490"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="8"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1898949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="547" mass="60077" checksum="B1773455D8A37227" modified="2025-10-08" version="1">MTMGESAESLNSTAKASTGSSRGQASLELDAVDHALLREAQRKARENGTALGTSPHRKRQRINGDRFIPTRSGQDLQASFSLLHEEGSPATPPRPKKRTPHGELDFQKTEEANRVFSKLLRAELFESSVPHDFTTRGSGMRSHTPPAPVGNGAVSNISPSTPSKNLFTYVSPAHHSVEGHPTPSKTPQGRHGPNLDTRAEIYSLSPVRLGSQQMLTSPRRQPRAVSKIPYKVLDAPELADDFYLNLVDWGSANVLGVGLGSSVYLWNAQTSRVNKLCTLEDDTVTSVSWIQKGTHLAIGTGKGLVQIWDAERTRRLRTMTGHTARVGSLAWNTHILSSGSRDRLIYHRDVRAPDQWLKKLVGHKQEVCGLKWNCEDGQLASGGNDNKLMVWDKLSDTPLFKFADHTAAVKAISWSPHQRGLLASGGGTADRRIIFHDTINGTITNQVDTGSQVCNIAWSKNSNEIVSTHGYSQNQIVVWKYPSMTQVASLTGHTYRVLYLAMSPDGRVVVTGAGDETLRFWSIFGRRPGAKEEDESSGRISDWAVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFL3</accession>
    <name>A0ABR3ZFL3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vacuolar protein sorting-associated protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">VPS8</name>
        <name evidence="4" type="ORF">Cpir12675_001637</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000027">
        <property type="protein sequence ID" value="KAL1898977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059070">
        <property type="entry name" value="TPR_VPS8_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045111">
        <property type="entry name" value="Vps41/Vps8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025941">
        <property type="entry name" value="Vps8_central_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING VPS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616:SF8">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 8 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23410">
        <property type="entry name" value="Beta-prop_VPS8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12816">
        <property type="entry name" value="TPR_Vps8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25066">
        <property type="entry name" value="TPR_VPS8_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 8 central" evidence="2">
        <location>
            <begin position="653"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="domain" description="VPS8-like TPR-like repeats" evidence="3">
        <location>
            <begin position="1199"/>
            <end position="1390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1447"/>
            <end position="1502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1475"/>
            <end position="1485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1543" mass="171071" checksum="5BF4D08C47EF381F" modified="2025-10-08" version="1">MDISTAGTHSDSPHSGSPHLEQHNDSAQTSSAADEPHIEQSFEDDNRDDGAASLLHTENAYSQSQIDINHSGLAQDVPSWASVALPGSSSSSINASEIVVQGDNIANVAQPPQSPQQSIKSDLDDAASIQGSFLSSPRSSILPSAALHRSDTGSPARGTSKGFILMFDYSQNLKGVIGSGTKAIECGAVTSIAISADHSTVAGGHMNGSIFTWETSKPTRTFLSIPPIAVTDKAERTSDGHMPDFAVIHLGFLGTRRTALVSADNRGMAFSHLATRGTGALGRMVKTNRILGRYPDALLTSTERPVKPSTVLAFAPLPLGNAERATDSMGLTAMLTPYLLVIVSTTPVAQTQHKVARPKNAGSQSSLSGCLSWFPAGKLKVADAESGSDISKAKLVYCWSNILSVMDVDEILPENPNKPSTLEFRTRNRWKCDEAIVAVQWLSRSVITVLTATQRLVVIEDRSMRVTDAFDLLHKSIYNVDFFSQQLRPLIGQVDAQDDGNNASTHSVVCDAFYMSLKVFKGRFFLLGIEDLSIGALSNWYDRLVALMNNGDYVASMQLAISYYTGDSDKLTVGLPEDATIRQSIVSSKAFDLMAESLAHIATRRKKDSTCISESTLKDLADVFFLACKTLENIDFLFDVVYDWYEENSYQGLFLETLEKYIVAEAITVVPPVVMKALVSHYVEKGMETRLEEMICHVEPSTLDLDQITALCKQHGLYDALIYVWNTGLGDYITPLIDLLDLLVHSVSLQESALMQTKTQGCNEVHIENAAKIFPYLAYTLTGRVYPMGDMLMEKDATKAKSEIYWFLFSGNSVEWPRGSKQKFITCPDRPQEPSFPYLRLILRFDAPSFLSAMNEAFEDSFLNDSPDKQIGANIGGDVPEEQVFGLTVDRQYIVSILLELMGPSVEFSPSDTIYLDMFIARNLSKFQQYLIFPGSTLTKVLTELCRYSEQDLVEDAQLSAEYLLSVYHPPDMDVLMPLLREASFYRILKRIYLSNREYESLVEVYLEDPYNQISLFDCLADCLRTAKSLTLRQRDSLYDAISKHASALIQLDPQTAAITFATQNLSLHRRILDSTMDFPHAQYMYLKTLLEPDASLETVDESVTNDQDLVELYVRLMCTHDASHVCDYITLHHVPNLRLHKLLETLEDTGVVDAVVILMASQGLIKDAMARLVKHLETLEVAFRYTFTGSNHSTNIKSTADDLLQSVQKFIHVGIWLCNKQQVLGTPFESAKSKAAITPAPKRSSMIRGEPLSETESLWLTLIRASVQMTKSLSLDIDDFVTSIDLDRERLEIQVRSLVQHVFTALLTATANLNLGVKTSHSVDSNVTFLRILQAFLTDEAVSSPSLADLRSVLSSIFAAYAYEESILQLSHRLLNQSLFLSMTQSIQLKQRGWRPRSSTCEACGRRLWGPGVSGNIYKAWELKQVRKAEEQRNVTNSARGLVDSRGKSKVAVTESNKLASGHHDEWPAPSSIQLQQQQQEQQLTTDYHPGNANPTLDTTGQDIGVDRGQDLDDIVLFACRHIYHRKCLETESSTMKCPRLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGE3</accession>
    <name>A0ABR3ZGE3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Coronin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CRN1</name>
        <name evidence="8" type="ORF">Cpir12675_001245</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the WD repeat coronin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000018">
        <property type="protein sequence ID" value="KAL1899746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015505">
        <property type="entry name" value="Coronin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015048">
        <property type="entry name" value="DUF1899"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10856">
        <property type="entry name" value="CORONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10856:SF0">
        <property type="entry name" value="CORONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08953">
        <property type="entry name" value="DUF1899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16300">
        <property type="entry name" value="WD40_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM01166">
        <property type="entry name" value="DUF1899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01167">
        <property type="entry name" value="DUF1900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4 5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="DUF1899" evidence="7">
        <location>
            <begin position="4"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="77"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="133"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="175"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="427"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="464"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="481"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="500"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU280818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1899746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="620" mass="67196" checksum="6469D22AE33FDF59" modified="2025-10-08" version="1">MSGRFVRASKYRHVFGKPTRKEFCYDNLHISRNAWDSNLVKANPEYLSVNWESSGGGAFAVIPVEERGKLPDQIPLFRGHTGPVLDTDWNPFNDHVIASASDDGKVCLWNVPQNFTLYTDAEDMPNVAPSSTLSGHTRKVGYVLWNPAAENILASASGDFSAKVWDASTGSPALSLVHNDLVQSMSWNASGTLLVTTSRDKKITLWDVRQEKPASQHAGHAGAKNSRVVWMGEHNRFATTGFSKMSERQIALWEPGNSDPIGGFTMLDSISGVCMPFWDEGSNCLYLAGKGDGNIRYFEYEADKFEFLTEYKSADPQRGIGFVPRRGINVRDNEVMRGYKTVNDTYIEPISFTVPRRAEVFQADLYPPATGLKPAESAQEWLNGKSDIPPKISLESIYNNQAPVEVAAAAPAAAPVAAAAEPQPIAAPAKKEEPAPVSRSVPASVKDQKESISNMANKYKDNEEASSSETEEASSFDEVPARSSSSSRPTPRSSVVFSSGTTPQPLKSSTVAKTSSGTGTPVRSPITPRPIPLPIVPTPTAMAAAAAAGYGSGTPSRSSSPVSNDVLIEIKKLIEVQTTKIEALTREVELLKRKVEGPAGAQDQSERIRHLELELEAARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHA6</accession>
    <name>A0ABR3ZHA6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Endo-1,5-alpha-L-arabinanase A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_001101</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Glycan metabolism; L-arabinan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000015">
        <property type="protein sequence ID" value="KAL1900098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08983">
        <property type="entry name" value="GH43_Bt3655-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046780">
        <property type="entry name" value="aBig_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050727">
        <property type="entry name" value="GH43_arabinanases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43301">
        <property type="entry name" value="ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43301:SF3">
        <property type="entry name" value="ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20578">
        <property type="entry name" value="aBig_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045128499" description="Endo-1,5-alpha-L-arabinanase A" evidence="7">
        <location>
            <begin position="19"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="Atrophied bacterial Ig" evidence="8">
        <location>
            <begin position="28"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="434" mass="47626" checksum="2A3DD9BE01AF2CF2" modified="2025-10-08" version="1">MHMYKSFFTLALASVALGLDKDTLSAVTITNVGSVRGNIFLPATAIDGSKITWSSSNPDVISADGIVKRQPQDTDLTLTATAADGTQSFTREFAAKVIKSYTVGEMAGYGFAFFTGNSIEGENIYFASSVGNNALQWQELNDNKPVLRSNFGTKGLRDPFIIRSQEGDVFYLIATDLSIGSGTSWGDSVRTGSRYLEIWESTDLKTWSEQRHVLVSPETAGNTWAPEAFYDENQGAYIVYWASSLYPVDDKEHTSSTYHRMMYATTRDFVNFSEAKVWQDSKASLIDSTVIKNGVNFHRFTKDESSTSGCTDIIQTRSNDLLATVDRWTVIDTCIGQKAGAKAVEGPTVFKSNPGDANGDKYYLFIDEYGGRGYIPLETADIEKPEWKVSSGYTLPKSPRHGTVIPLTASELTNLNAVKSVSARSNEAGKLWIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHJ4</accession>
    <name>A0ABR3ZHJ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NdufS4</name>
        <name evidence="10" type="ORF">Cpir12675_001644</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion inner membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the complex I NDUFS4 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000027">
        <property type="protein sequence ID" value="KAL1898984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.190">
        <property type="entry name" value="atu1810 like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006885">
        <property type="entry name" value="NADH_UbQ_FeS_4_mit-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038532">
        <property type="entry name" value="NDUFS4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12219:SF8">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 4, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12219">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04800">
        <property type="entry name" value="NDUS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5 9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1898984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="201" mass="22753" checksum="BE3A8F22E5018B00" modified="2025-10-08" version="1">MSSMRTSSVRVLRSAVAPTARSFSHVSRLQQQKSVTTTNESVTVAVPVSNQPDYTIEPDKATSTFTPVPKRIQVGNENIPVSAAISSGAPIELQGRQVRIYQETKPATQSGDWKGHHWRMDWDVLGKGHRWENPLMGWQSSADAMQGTRINFETKEAAIRFAEKQGYEYFVQEPQRRRTVPKSYADNFLYSAKELKHVRTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI52</accession>
    <name>A0ABR3ZI52_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquinone biosynthesis protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">COQ9</name>
        <name evidence="10" type="ORF">Cpir12675_000975</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Membrane-associated protein that warps the membrane surface to access and bind aromatic isoprenes with high specificity, including ubiquinone (CoQ) isoprene intermediates and presents them directly to Coq7, therefore facilitating the Coq7-mediated hydroxylase step. Participates in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the COQ9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000013">
        <property type="protein sequence ID" value="KAL1900393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.10">
        <property type="entry name" value="Tetracycline Repressor, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013718">
        <property type="entry name" value="COQ9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012762">
        <property type="entry name" value="Ubiq_biosynth_COQ9"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02396">
        <property type="entry name" value="diverge_rpsU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21427">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21427:SF19">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08511">
        <property type="entry name" value="COQ9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="7 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="10" id="KW-0830">Ubiquinone</keyword>
    <keyword evidence="4 8" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="domain" description="COQ9 C-terminal" evidence="9">
        <location>
            <begin position="160"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1900393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="258" mass="28389" checksum="369D842F8CA6898F" modified="2025-10-08" version="1">MSLLMRRQATQIAASNTKCLVRSGILSRTRLYHSYDHPSPPSKQFTPTEKQILGAAYNHVPELGFTTAALTVGAREAGFPEVTAAAVADGAFALVRWHLVNKRQALANQSKALLGEEPLKSSRIVERVEALTWERLKGNGEVIHKWQDALALMAQPSYLPESVKELGALTDEIYFLAGDVSVDPSWYTKRGSLSMIYASSELFMTNDRSQDFADTQEFLSRRLRETSALGNVMGAIGQWTGFTASAALNVLRSKGIRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIC7</accession>
    <name>A0ABR3ZIC7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8004 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000887</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058317">
        <property type="entry name" value="DUF8004"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39601">
        <property type="entry name" value="CHORIOGENIN HMINOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39601:SF2">
        <property type="entry name" value="CHORIOGENIN HMINOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26013">
        <property type="entry name" value="DUF8004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8004" evidence="2">
        <location>
            <begin position="471"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="730"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="951"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="995"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="750"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1010"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1050"/>
            <end position="1059"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1125" mass="122715" checksum="9F647768AF866167" modified="2025-10-08" version="1">MSGRSAHVRKKITHTNGTSDKASIISGSAHEYGVRSPTALSLEANDAIFSDFPIPHGGNADAGTSTGVATTSANFLKFSDGSQGSLASIDHSRYADTSRFLPSTASVNSSSTGSDDNRRPEILYGYGRTGRPAFKTEQVSGIEKSGLRSIIDRKSEGVRRGLAKKFAFRGKNSQSSDNPLKIPDLPISIPTMSHGQGSHTHMPQHKQQSHLHPPLPPLPPLNTKQQPGFAGSQYPYSPDSATGASQKLGQHQFGVQHPLAGSTEAWTPPSAGAPPMGKLPPVPQTLQPLPPIKRWVGFSRPVQRWSKLRKDPELWDPNGDVFVYFGQRSQTNRSPPSFRLSSHVIEATESRYLLTMLRDGTIDDDYDRLPPSPPSASREGFREIGKENQPASTMSETASIADAEGQISYEMFFPTPPNISKVEQLRYQITTRNLFALLYHTSLVGLSLCQALTDLVSRLDVCMSADSDSVSTVINYIQTRGIDDVRNDPETAVSLLAWTESARVRWDDGWKESFIHCAGMYGRQVEEAPDYKNVSQISRALLDRASLEMLVRVQQAEERLAEFQYADMWPGPELEVNPMARQAFSRLQRFFLAHYSQIYGCWPPRPEDWTKAPTTAPRVSGTTLGDDKDRYGEGEIWLSRTIAQALQRDFGALYDYLVNRDIVWDESEMRSTRKWMLASQCGKTDFDVDEDRVPMTDILVDFDNKHRYPHIPHPYPLVPESIMTITPAGAAGASGKEAGSRFKPTWRSNAQPPTTGGAGAPRAGPMERRVRLAYTESTNISVLGSSFVQSDLVDAFIRFERQDMLCEIDPAVARRGRWVLIYGILQTLASVSVDSPWARHHAGVAYHLSPRLKGARLPPWSVGNGAPVYSTAVDSVAKHDGFDDACHELSYCWAISQTWNGGSGDSRNVFESLPTSGRISPNAEMRSRIAARRSIRSTTSSLPMGMSASVFGESDSGHHHGNATARGANHVTMNRMRSRENMRNGLSAATLARGQSIMSNGGSGSGSGSRNGLRTDTSMIESSSSSEYSGSSASQFSSPRRNLWSDTGSVQGGSGGGSGNYARSSVSSASGLGSGFMPDGGLPPVSKALFHAKSMDREIGQASSLGPKGSFRDFDVLDVIDDYEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIW6</accession>
    <name>A0ABR3ZIW6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Lysophospholipase NTE1</fullName>
            <ecNumber evidence="3 14">3.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Intracellular phospholipase B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">NTE1</name>
        <name evidence="18" type="ORF">Cpir12675_001049</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis. Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 14">
            <text>a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15177"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16870"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:58168"/>
            <dbReference type="EC" id="3.1.1.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the NTE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.5" evidence="3 14"/>
    <dbReference type="EMBL" id="JAWDJO010000014">
        <property type="protein sequence ID" value="KAL1900365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056556">
        <property type="entry name" value="NTE1_P-loop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF29">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE SWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24179">
        <property type="entry name" value="NTE_Ploop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 13 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 13 14" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="9 13 14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="16">
        <location>
            <begin position="643"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="16">
        <location>
            <begin position="784"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="17">
        <location>
            <begin position="1162"/>
            <end position="1326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="256"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="483"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="576"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="696"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="13">
        <location>
            <begin position="1166"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="13">
        <location>
            <begin position="1193"/>
            <end position="1197"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="13">
        <location>
            <begin position="1313"/>
            <end position="1315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="322"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="623"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="13">
        <location>
            <position position="1195"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="1313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU362043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1900365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1466" mass="161781" checksum="782AF9713CDE15F0" modified="2025-10-08" version="1">MDSVLSSSEALSSSANAIARSLETAAAGVAELTEAQGPSTWLGLLGRIILFILHLVSSVLFWSLRLTTMSLPTFIFTAFSSTWTVTMNATTFAVAWVVRYRFLNMYARLPPEPQRKEPNVDLPPDNHDEGHKNGISNYLDEFLSAIKIFGYLERPVFHELTRSMQTKRLVAGEAFNLEEEKGFCIVVDGLVEIFVKSGSRTPHEKPDTYDSDSTDYDSPGYAPHQYQLLTEVRNGTPMSSLFSIMSLFTEDINVYSSDDEPTRKQPDAFPPEHPFRDHNPPEMASAPGTPPLVATEPTQTDASGPFPRIPAIDLQSTSKPGNGHRHSRPPLKHRGTSVSAHPDIIARATVDTTLAIIPASSFRRLIKVYPKATAHIVHVILSRFQRVTLANAYNYLGLTDDVVRTESSLIRYTLCQLPNELRGEALNRLKEKFRDERDNLRENGEDPKVIALHNLVLGRRRRSSTGLRKDAVLSSLSKQIVEGSTGSTIAPPRNPLPRASKPTELVGHARPPKRVGTYGTSPRVSLEHSSRRVIDPFAKQGTRKPIDIRDSVAEDNVFRASVLECILQSLGLGQSALPSRESESAEGSPGLGSFDRRARHTPTNAFGIMGPFESGSGEGDTESMASGSTSAFHSPSAHALADDMRDDLEILFFPKGSVLVEEGEHTAGLYYVIDGFLDMGTTNMETSTGILEVDPASYHTSSTSSPDEDGHEGIRSHRAKRRPRKSIALIKPGCLAGYIGGVTSYRSFIDIRAKTDVYVGFLPRASVERIVDKFPIILLTMAKRLTNILPRLILHIDFALEWVQVNAGQVLFHQGEESEAIYIVLNGRLRLVEEKKDSQINVLAEYGQGESVGEIEVMTESTRPGTLHAIRDTELVKFPRTLFNSLAQEHPNIMMKVSKIIASRMRKLIEDPSTLNLGDSRSSAAFQKGFSTNNLRTVAVLPVTTGIPVMDFATRLMAAFAQVGPPNGAVCLNQDVILNHMGKHAFNRMGKLKLAQYLADLEEKHNLVLYVADTSVNSPWTQTCITQADSILLLALADGSSEIGEYERFMLGMKSTARKTLILLHAERFSQPGLTRSWLRNRMWVNGGHYHMQMPLSPSSIPVTQPRRLGSALKERVQIIQAEIQKYTSRKIRPGQYYTPELPSKGDFNRLARRLCGKSVGLVLGGGGARGIAQIGIIRALEEAGIPVDLIGGTSIGSFVGALYARHADVVPMFGLAKKFAGRMASIWRFAFDLTYPTASYTTGHEFNRGIFKIFGNTQIEDFWLEYYCNTTNISKSRQEIHTSGYAWRYIRASMSLAGLLPPLCDEGSMLLDGGYIDNLTVAHMKSLGAAIIFAVDVGALDDNTPQTYGDSLSGLWAFLNRWNPLSGHPNPPTLSEIQARLAYVSSVDALERAKTMPGCIYMRPPIDDYGTLDFGKFTEIYDVGHKFGTNFLAQLRKEGKLPLQEETEAASKALRRTMAPRRASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJJ1</accession>
    <name>A0ABR3ZJJ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">V-type proton ATPase subunit c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">vma16</name>
        <name evidence="12" type="ORF">Cpir12675_001046</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="function">
        <text evidence="8">Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9 10">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the V-ATPase proteolipid subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000014">
        <property type="protein sequence ID" value="KAL1900362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18177">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6F_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18178">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6F_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.610">
        <property type="entry name" value="lithium bound rotor ring of v- atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000245">
        <property type="entry name" value="ATPase_proteolipid_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10263">
        <property type="entry name" value="V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00122">
        <property type="entry name" value="VACATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="129"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="166"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="11">
        <location>
            <begin position="48"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="11">
        <location>
            <begin position="132"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00045519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00046480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1900362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="201" mass="20562" checksum="2D6EE1F63A8AE32D" modified="2025-10-08" version="1">MSLLTYGLGAFTSIVTIAGALMLFTGSGEHFNVGEFLESVSPIAWASMGIGLCIGLSVVGAAWGIFLTGSTILGAGVKAPRIRTKNLISIIFCEVVAIYGVIMAIVFSSKINKVDGADAFSGNSYFTGYALFWSGLTVGFCNLVCGVSVGINGSGAALADAADPTLFVKILVIEIFSSVLGLFGLIIGLLVSGKAPNFGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK70</accession>
    <name>A0ABR3ZK70_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Hsp90 chaperone protein kinase-targeting subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CDC37</name>
        <name evidence="10" type="ORF">Cpir12675_000690</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDC37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.610">
        <property type="entry name" value="Cdc37, Hsp90 binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004918">
        <property type="entry name" value="Cdc37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013873">
        <property type="entry name" value="Cdc37_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013874">
        <property type="entry name" value="Cdc37_Hsp90-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038189">
        <property type="entry name" value="Cdc37_Hsp90-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013855">
        <property type="entry name" value="Cdc37_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12800">
        <property type="entry name" value="CDC37-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12800:SF4">
        <property type="entry name" value="HSP90 CO-CHAPERONE CDC37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08564">
        <property type="entry name" value="CDC37_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08565">
        <property type="entry name" value="CDC37_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03234">
        <property type="entry name" value="CDC37_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01069">
        <property type="entry name" value="CDC37_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01070">
        <property type="entry name" value="CDC37_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01071">
        <property type="entry name" value="CDC37_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101391">
        <property type="entry name" value="Hsp90 co-chaperone CDC37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cdc37 N-terminal" evidence="9">
        <location>
            <begin position="2"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc37 Hsp90 binding" evidence="8">
        <location>
            <begin position="202"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc37 C-terminal" evidence="7">
        <location>
            <begin position="389"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="191"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="462"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="191"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="203"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="463"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="489"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1900815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="503" mass="55733" checksum="B3EF027AA3E69EF4" modified="2025-10-08" version="1">MPLNYSKWDTLELSDDSDVEVHPNVDKKSFIRAKQNQIHMERAQRKAQIEAYHYEKIIDTGLLSRIEALIAYLKSNSAAIASGEKNAGQVAFAAVMETAPKDKSADNPPPRPQVMQEADKKPPTYTEMLMGLLDQVNKSLEEKKVATEGRFNAIIEELGVHVAKIKQLSAENAKKCEELEKLEGKKITSESYHTGFDSSHVNKNKEPAGESSKAKEAQSQVELINPNFDMNTGREKGAPPSALENDEEEISASPLAKQFACIPPNDHAAALSFLRANPQVLSEREQDGLMVDAFDAALEGRDDLCRQNVHQALLIQYCRALGKDGVAMFFRRITTRGHQAQDVFFKDVQDTYMRIRTRAREIVRERAAKPEGVEQIQLEAVEPGTEISIEIPPKDSADPEVQASRIIFESFSEDMQKVLESGSLEKVNKVLGEMKVDEAEALVGQLGDAGILGVNELIDATTEEGKQRQAQIKEEGKQAKEAREKAAAEEEATLEPEAVPDPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL85</accession>
    <name>A0ABR3ZL85_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000712</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051783">
        <property type="entry name" value="NAD(P)-dependent_oxidoreduct"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079:SF5">
        <property type="entry name" value="DEPENDENT EPIMERASE_DEHYDRATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G00180)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079">
        <property type="entry name" value="PROTEIN YEEZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="314" mass="33351" checksum="CAF9CD2C96C83F0D" modified="2025-10-08" version="1">MSTKNAFITGGSGYIGSEVVKKAIAHGWTVRGLSRSESSDAKLAALGATPVRGELTSLDILASEATKADYFISMAYDLNLDKPSIDMKDASDTDRALIDAVIGAMRPGSVFVQTADVLVAMQPTDGSEADETAPYADTAFGIRGHNETYALNKGVEHGVVVNVVRSAAFMYGEQASSVAMMMASAAEKRSAMYIDEGSALVSSVHVRDCAEVYVLAAEKRTSGIYHAVSDNNVSFKQISEAISEVLKVPAVGIPKATLESMTTPMMVTFLTSSSRASSRKAREQLGWKPEEKPVLEDITKGSYAKLADSLQAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLF7</accession>
    <name>A0ABR3ZLF7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sidoreflexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">fsf1</name>
        <name evidence="10" type="ORF">Cpir12675_000498</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the sideroflexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004686">
        <property type="entry name" value="Mtc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00798">
        <property type="entry name" value="mtc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11153">
        <property type="entry name" value="SIDEROFLEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11153:SF6">
        <property type="entry name" value="SIDEROFLEXIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03820">
        <property type="entry name" value="SFXNs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1901265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="340" mass="36659" checksum="1275E02A9F546DA7" modified="2025-10-08" version="1">MSASILGPRELPESQYDLQTYWGRVQHAVGLTDPRTLLVGSTGLEKAKQQLAEYKQGRISHMTPELWMAKKIVDSTLHPDTGEKVFLPFRMSSFVLSNLVVTAGMLQPGLGTIGTIGWQWGNQSLNVAINNANANKSSPLSWGQVAQSYFLAVGASCTVAVGLNKLVPRLRGISSSTRMVLGRLVPFAAVASAGALNVFLMRGEEIRRGIDVFPVLDDAGKEKLKAEGKAESDIQSLGRSKKAATLAVGETALSRVLNSSPIMVIPPLVLVKLQQTEWLKQRPRYTTPINLGLILATSFAVLPLALAAFPQRQSIAADSLEPEFHGRGGHNGLVVFNRGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLF9</accession>
    <name>A0ABR3ZLF9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase type 12 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase type 12" evidence="1">
        <location>
            <begin position="82"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="305" mass="33219" checksum="9FB494520EDAE36E" modified="2025-10-08" version="1">MSSPELRNLRLRKPNDSVCAISSATSSPAAHLSNLYFGIYDTSFLTRYDFWVLNITCSYIWRVSTRSVLLPFFASHFSASHLDIGVGTGYFPATSLSLGIAPACSSPAPRIALWDLSSQALATARACILSAAPGAQVTAIQADATRPLPAAERALLTEPRLSECNDSGFDSISAFFVLHCMPGDTYTKMQALARNAASHLNPNGTFFGSTIVWSTHRVTSRPATQGLRIGTGSEYTIEGDSREDHGWFLPTLLMWAYNQTGIFHNKGDNPDAVIRALEDNFESVESWIVGTALLFRAKSKTSRPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLX6</accession>
    <name>A0ABR3ZLX6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF3074 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024500">
        <property type="entry name" value="DUF3074"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40370:SF1">
        <property type="entry name" value="DUF3074 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40370">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11274">
        <property type="entry name" value="DUF3074"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3074" evidence="1">
        <location>
            <begin position="124"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="320" mass="35938" checksum="1FB80DA97645EA38" modified="2025-10-08" version="1">MVSSVTLGPLIRLWGLKVTELPQPSSPPDELQPFVISVLEEAINFLDSVPTSRSSAPTIAKNGQSTLCSSSRTLWKFKDSYPYSGGNTPLISFQRTVTPKQLRGVADKHNVVQEGSRDFRTEFWVCRQSEHEDAARKGTASWDEFARCFRDENAEAEKALTPKVVDREIGVQWNCEGIVTNIEEKTWGNITLKLKESRHRFGFLFKDRAFAVLQMTATMVGAQEFIIVSIAVNETRDSPLCRISKSPSVVNGAYSSVERIRKLPQGTIEWTVATASDARGILPRWAQRRLVPPKIRQNVPLFLTWLATQRTRDIQGTTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLY1</accession>
    <name>A0ABR3ZLY1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sugar phosphate transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_000729</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TPT transporter family. SLC35D subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="160"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="10">
        <location>
            <begin position="86"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="27"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="456"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="456"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1900853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="497" mass="54603" checksum="5AB5E10E2275C892" modified="2025-10-08" version="1">MSHHEKIDRFPDFVDTTSHDTAIVSAQRWTPRRDHSRSSSSREKLDGSPLPGRRTSLSNALRRVRNSSISQADIAGALRAPISPMLVVLCIIWWTTSLLTNTSSKSILNAFPKPATLTLVQFVFVSSYCLLWSWLASIFPRLKRIIPTLKYPIRKPSLDIARTTLPMALFQIGGHLLSSNATSMIPVSLVHTIKGLSPLFTVLAYRLLYNIPYPVATYVSLVPLTLGVCLACSGNITFGGQFLGVIYALLAAIIFVTQNIYSKQLFNDRAKAEADGMGTQSKTLDKLNLICYSSSIAFFLTLPIWFFSEGWSLLADFFSDGAVDLSGRPGAMDHGRLTLEFFLNGSFHFGQNLIAFVLLGMVSPVTYSVASLLKRVYIIVASLIWFRNPTTRIQALGISLTFLGLWLYDRSNEGNKADRKVRTMAAAPNASPLLPMNTSSTPYVSGPTASSSYGIVSGKDSTMRQTQAPTWLPPGTKQEDTWRLGDQQAGIVNSVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMK9</accession>
    <name>A0ABR3ZMK9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNase P and RNase MRP subunit</fullName>
            <ecNumber evidence="2">3.1.26.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">POP3</name>
        <name evidence="2" type="ORF">Cpir12675_000523</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.5" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013241">
        <property type="entry name" value="RNase_P_Pop3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28272">
        <property type="entry name" value="RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28272:SF1">
        <property type="entry name" value="RIBONUCLEASES P_MRP PROTEIN SUBUNIT POP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08228">
        <property type="entry name" value="RNase_P_pop3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="266" mass="29267" checksum="709E134BBC745877" modified="2025-10-08" version="1">MASKIQSQARKKTVYQLGTPFATTEWPKVSPEHQDVILELLCSFLEPLGQYRMRHCELSKGKSSRKRKREAIKKAKAKGLDTPTKSLEKPPPPVIIEYVDVGLSGITRNLQILSFPKLQNAKEIQADATPQQDQPYAAIFIARSGQPSMFHSHMPELVAAASRHPSAVKPIRLIAISQPCSERLTKALGLPRVSAIAIRTGAPHANALLDYVEKHIEGISSAWIDSATKYFKFQALNVVAVQTTIGQRKAHLVDGTTAKQTSATRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMP1</accession>
    <name>A0ABR3ZMP1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">NADH-ubiquinone oxidoreductase 12 kDa subunit mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_000360</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039993">
        <property type="entry name" value="NDUFB10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13094:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13094">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE PDSW SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="104" mass="12058" checksum="826CFFA42C7B129E" modified="2025-10-08" version="1">MPTPESEMFLAQKPKVPPTFDGVDYDDHNAFKAAQDAIIREQWVGAMMVRLVGEELGKCYMREGVNHLENCGQLRERYLTLLKEKKVTGPLFQQLNYIKKQEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNB9</accession>
    <name>A0ABR3ZNB9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="113"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="177"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="444" mass="48177" checksum="548E658ED555E4D8" modified="2025-10-08" version="1">MNKTWTDRADRDLFLSILMVKSVGIVSGAEWSQIGALMRGQGHGFTNEGCRQHFQGMRRKSAKKDTIAKPIDVGSQDPTHDPIMRRPGPGRRKIRKSASADSQAPDNLEHTATSQLPQDQQQVQDHQTNHHQQQQQPMMVNQSMVASRSLSQSLPQSMSESMSQLHHTQHHHHAHQQHAAMLAHVQQQQEQEEEQEQHQQQEHQQSLFQHYQIHDPSLVNITESLPVDLDPAAPDAGIDTTATDHDIDALDVAVSMAPSPPTDPALVVAVGVSVDESPSLQSLPTTHQHSNNNPSSISHAATEPISDIRSQVHSHAHLDTDAAVLQHALGNEDTNNGPPAKRQRIDLDANVGISANGDNHGLDSVDSTEDLMSSHLQDNVVDVVSVVDVDVGVDMGVGVGIESQDPTQHSGLSDDDAAAAAVLALQEASGPETGVEPYESTFEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YF68</accession>
    <name>A0ABR3YF68_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006825</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000386">
        <property type="protein sequence ID" value="KAL1886943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1886943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="392" mass="41253" checksum="CCD0E3E0F49C9D9F" modified="2025-10-08" version="1">MSSYINTTTSGYAIIGVLTVLTLFLMSKKQQPVATPMVARVASTVPTAGASKAKKQRSKAYSTKAAAVPAEPSLKPAATSKDSTGTTKDEITNNEFALQMAGLKEGTSLAAKATAPKSKKKSKAKKSKATQETDVDDEVTAPSTSTGRDADDDQSPATSPDVKPTDSTGVADMLEKSGAAPSVLRLTDTATAPAKPVKAAKAEAPVETKKQRQNRKKAEAAKALRAETEKERQVQLEAQRRTARIAEDRPAKDGSQFAAQQKAWTEASPAVTAAPSTMLDTFNAPVAAPAVKAEKSAPIALSEEELIEMAKEDSSEWNTVNKKAKKVKKAAPVEEAQPDLIETKTSSPAANVSTPISKPVANVSKPAVLKSFGSFTALSADEKLPEESEWDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YF76</accession>
    <name>A0ABR3YF76_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Potassium transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">KCH1</name>
        <name evidence="3" type="ORF">Cpir12675_006810</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000382">
        <property type="protein sequence ID" value="KAL1886960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031606">
        <property type="entry name" value="Kch1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36424:SF1">
        <property type="entry name" value="LOW AFFINITY K(+) TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36424">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16944">
        <property type="entry name" value="KCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="221"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="316"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="572"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="450"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="528"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="602"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="698"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="732"/>
            <end position="751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1886960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="799" mass="87884" checksum="2E660712216936C5" modified="2025-10-08" version="1">MGCCGHSRKAKQYHAEQKWEYINLNDFKAKGCLTVFAYGYLWFSLLISVAVYTVDTFTAVNLLVLNNWTSQIKPDINLDIAKWVFSICIILSFINLGFEHIRAWRVMHRGNIAECYLDNLAARLDSTRLGKGQGYRRFLVFAELTKSKKGAEYVALFSYFSLQAWVRVLICSGPRQVINVFTIKALYVADLNPGADDVEGSLVGFFENLSTLATEDYQKALVLAGMCFTLVVWIFSLLFMILAIFAYVFFLWHWIPRADGGLAGYCERKVNKTLVKIVSKKVNKALRQEEEKRIKDAFRAGPSNLQMIDRKATLPTLPNVGSGKADALPQMPTLPNLEAKPSMPSLERKDTMGTVSTLPAYTSRPSNTDIELNPLENHRQTPRSQGTPAPQSGYSANASLLGNAQDMAYSNSPPGPSSLGPSAQMNRPQSPFIAPHRRLAGPSATMDYGRSQSPAPTMTSSQYPQRQQTQSPYYANSTRPSNGSASVRQPGPPQYGDINMARTQSPAPYGQPPNRQPTIPNMGPGNIPRSQSPATFGQQLRQPTLPNILPEPTLPTILPEPTLPELDFGNMARTASPSPHNDMARAASPNPFNQEPRKFNPFNPNGQTAQNTTMAIAELGSNSPPRPTRPRPAMKRNDSTPITELATGSPPRPSRAATDVQPVELGANSPPRAMRSQTSPFDVFAAGDGRQSPDRSAIPNTDVSGHLQNPKPKTNVISATSSTLTGFRPFTPSMTESNLSQAGAPQSQGIQRPTGLPMSHGYTGSGYGSDYFQDYRESTQSSAFDLEYYDLERQDDQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFS3</accession>
    <name>A0ABR3YFS3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glycine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Diadenosine tetraphosphate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GRS1</name>
        <name evidence="10" type="ORF">Cpir12675_006790</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000376">
        <property type="protein sequence ID" value="KAL1886979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00774">
        <property type="entry name" value="GlyRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00858">
        <property type="entry name" value="GlyRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027031">
        <property type="entry name" value="Gly-tRNA_synthase/POLG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033731">
        <property type="entry name" value="GlyRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002315">
        <property type="entry name" value="tRNA-synt_gly"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00389">
        <property type="entry name" value="glyS_dimeric"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003211">
        <property type="entry name" value="PRK04173.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745:SF0">
        <property type="entry name" value="GLYCINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745">
        <property type="entry name" value="GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01043">
        <property type="entry name" value="TRNASYNTHGLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="9">
        <location>
            <begin position="215"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1886979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="657" mass="73355" checksum="4805D324DF59CE7A" modified="2025-10-08" version="1">MAANTTTLKGQSLDRPALDALLRRRMFYTPGFEIYGGSAGLFDMGPPGVTLQDNIISLWKKHFINEEAMLEVDTTVLTPYEVLKASGHCDKFTDWMCKDPKNGELLRADHWVKDTLKARLNANKLARGETVTEEEDPKKKKKAGKVAVQKLTDEAVKEYEEILARLDNYTGAELGELIVKHDMKNSATGVIPGEPKQFNLMFQTQIGPNSANVGFLRPETAQGQFLNFSKLLEFNNNSMPFASACVGRSYRNEISPRGGLLRVREFLMAEIEHFVDPESGKKHARFAEVADTELVLLDRHTQQDGKTDVRTVKIGEAVSSGLVNNETLGYYLVRINKFMEKIGVDMSKLRFRQHMANEMAHYAADCWDCELLTSSGWVECVGCADRAAYDLEAHAKRTGSPLTVRERLETPIEEEKWEVEPNRKVFGPLFKKDAKAVENHLISLSQEELAALSKQLAEEKNITITVPGLAGASTIGAEALKIELKKNTIHTREYFPHVIEPSFGIGRIMYSLIEHSYWTRAADDGGDEARGVLSFPPIVAPTKVLVVPLSNNPDFKPLTDKICRKLTSQGIWVRTDISGATIGKRYSRNDELGTPLGITIDFQSTSDNTVTLRDRDSMTQVRGDEDAIIEAVRSLVTGQKTWADIEKELPKFDGQKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGQ6</accession>
    <name>A0ABR3YGQ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">AMP-activated serine/threonine-protein kinase regulatory subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SNF4</name>
        <name evidence="7" type="ORF">Cpir12675_006777</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-AMP-activated protein kinase gamma subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000373">
        <property type="protein sequence ID" value="KAL1886993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04618">
        <property type="entry name" value="CBS_euAMPK_gamma-like_repeat1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04641">
        <property type="entry name" value="CBS_euAMPK_gamma-like_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050511">
        <property type="entry name" value="AMPK_gamma/SDS23_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780">
        <property type="entry name" value="AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780:SF35">
        <property type="entry name" value="LD22662P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0129">CBS domain</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="442"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="520"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="592"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="30"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="88"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="234"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="94"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="106"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="126"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="234"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1886993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="678" mass="73197" checksum="55EEDDDAEA5F6ED7" modified="2025-10-08" version="1">MSGSEAPVSHPSPPPPLLMSTELATEATEANAANSAASLGMEQKPHEAAGKEEEEEALIAVNDSNQQSAAATVIDTTAAKTAADIAVTGDHHNSGTPTLPQPQSKTDNDIVIDNHHNHTSTNNDNQPLNPTPTIAQSDAVDPIAPTTAVITTTSSGPILHSSDKPEQLAAAILAATSSEINAATDTPPPEPALELEGEITSEILAPAPETDEDPALQQATDVGTGASCIANPASLHSSTASSSPQSIVTPSPFIQNTPANSSSVSGLPPPAVAATLGSIAPPLLQYPTEPLGRPTSPGHLITLNDLTEPITPFSTKFSPSNIMVQSQAEESLPEAEYLQLLGLRTIRRFLKVRTSYDVLPMSFRLIVLDNNLLIKKSLNILIQNAIVSAPLWDAATSTFAGLLTATDYINVIQYYCLFPEEMGALEHFKLANLRSIENAIGVSQIEDVSVKPTKPLYQALRKMLQTRARRIPLVDVDEETGRETVISVITQYRILKFIAVNNEMNTVLLRKSIKEIGLGTYTDLVTLSMDNTVLDAVHFMVQHNISSIPIVDENNRVLNVYEAVDIIPCIQGGIYEELSEDIGTALCKRADESPGIYTCSEEDRLDSIFDTIRKSRVHRLVVVDDDTKLRGIISLSDILKYVLLHGEETDNLYGEEEDEQEINRQNQIAARYTQPQQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH48</accession>
    <name>A0ABR3YH48_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006466</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SAP18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000305">
        <property type="protein sequence ID" value="KAL1887649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.550">
        <property type="entry name" value="ASAP complex, SAP18 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010516">
        <property type="entry name" value="SAP18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042534">
        <property type="entry name" value="SAP18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13082:SF0">
        <property type="entry name" value="HISTONE DEACETYLASE COMPLEX SUBUNIT SAP18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13082">
        <property type="entry name" value="SAP18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06487">
        <property type="entry name" value="SAP18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="116"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="187"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="187"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="227"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="252" mass="27677" checksum="3812AC08B4A3164A" modified="2025-10-08" version="1">MTNWHCDDDPTPFHLRVYTRNNTFIHPDDLASHRPPKHLDIYTLSSCTLGNLALLIAAERPETFPVPALGTRVAFQHIYPDPSAHDSSSSASLRLRYIARDLGNVVLGGSGIGALAAPEDTDDDEDSSMARLDSHGRKLPPLPVDEALKFETRTLKSLRFVPGDAISVAVLPPMDDGHVAPMTTLRRDRGAVDRDRSGWGMGRERGDGSGAGREGRRSGGGGGFDIPRGDWRRGDRLPEEPSTRAQRGRRRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHD7</accession>
    <name>A0ABR3YHD7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ferric-chelate reductase (NADPH)</fullName>
            <ecNumber evidence="3">1.16.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Cpir12675_006630</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2 a Fe(II)-siderophore + NADP(+) + H(+) = 2 a Fe(III)-siderophore + NADPH</text>
            <dbReference type="Rhea" id="RHEA:28795"/>
            <dbReference type="Rhea" id="RHEA-COMP:11342"/>
            <dbReference type="Rhea" id="RHEA-COMP:11344"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.16.1.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.16.1.9" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000337">
        <property type="protein sequence ID" value="KAL1887257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF3">
        <property type="entry name" value="REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G13750)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="250"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="285"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="15">
        <location>
            <begin position="316"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="536"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="551"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1887257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="635" mass="71337" checksum="F75293B29B27B007" modified="2025-10-08" version="1">MGKGHIQDFDSATQLESHWGYADRVIPCVNDAGSCEYLDLVYGSHDRGMVYTGVFWLTVAFVLMCFAINRYISLSRALPLDSPAEAQLPMSGFLRVKTAVQSYLRRYLLPNNPLRFVFGYVTRYQVAVFGLFLVYMTIWSFVGLIYKKWKTPVKGEVDMYNTRSTLGPWANRVGVLAYALTPLSILLASRESFLSYATGIPYTSFLFLHRWVGYLIVLQSMLHTMGWIMVEAWLYKPQPEVWDTFVPQLYVKWGFVGLGLLTLIWFLSLPWAIRNITGYEFFRKAHYVMAMVYIGALIGHWKNLQCFLTPGICLWAIDRALRVVRPFQLHDRGNTWGIIPAQASVKLWKDDVNGDIYRLDFDIKQKSWKVGQHFFLCFPQSGWWQSHPFTPISAPPTTADAKSSPQGMTQSYVIRAKGGETKKIAALAESRLASDPKSTLSVIITGAYGENITESFTPQSNILCVAGGTGIAYVLPPLIQLARASNISSDRKIELIWVVRRKLDIEWIQPELETLLAPVSAKIVVKMFVTTETASDHGDAKVSANPEKQVSSDSNSSLNSETPYAIGWGRPELVATVREFVDTTIKGETTVVASGPLGMVSDLRRAVAVCNDGSKVWKGEERFSVRLVCDERLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIQ8</accession>
    <name>A0ABR3YIQ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription initiation factor TFIID subunit 13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_006263</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TAF13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000273">
        <property type="protein sequence ID" value="KAL1888201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003195">
        <property type="entry name" value="TFIID_TAF13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11380:SF5">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11380">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID/SUPT3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02269">
        <property type="entry name" value="TFIID-18kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="113"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="131"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="146"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00040136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="167" mass="18863" checksum="538BCC08E76BC2FE" modified="2025-10-08" version="1">MEPRARAIKNIGKMTFSNTELTQLLYAHGDVQAPLPETMRVLDEIATDFIQSLAFDATRAANYAGRQKVKFEDFEFVFRKNPMFLGKVQEVFEKKGEIDNARKIIDDSEHAIMKNAGNESKEKDTKKGGSTAKTAASPDNTKTKDDVDEEELGEADDYEMEDFVRTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIQ9</accession>
    <name>A0ABR3YIQ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ATP-dependent 3'-5' DNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">HRQ1</name>
        <name evidence="6" type="ORF">Cpir12675_006441</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000301">
        <property type="protein sequence ID" value="KAL1887713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17923">
        <property type="entry name" value="DEXHc_Hrq1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18797">
        <property type="entry name" value="SF2_C_Hrq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014939">
        <property type="entry name" value="CDT1_Gemini-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055227">
        <property type="entry name" value="HRQ1_WHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47957">
        <property type="entry name" value="ATP-DEPENDENT HELICASE HRQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47957:SF3">
        <property type="entry name" value="ATP-DEPENDENT HELICASE HRQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08839">
        <property type="entry name" value="CDT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22982">
        <property type="entry name" value="WHD_HRQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="356"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="5">
        <location>
            <begin position="576"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="182"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="182"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="891" mass="100083" checksum="79B0B5A732C4A103" modified="2025-10-08" version="1">MDETSTTCDKKRKSSDTKPYKRPTKKQAQCSKEPKTPGSSCGQGDVEWPELFKELEKLHRALNTIFTFCSARKHMPTAFDIIKSTVEANLRRPITIAEVAQVVAIQPERFQFEYVNEAMLQPLDLDPFVARLGAVENASRGRWIRADGADKDYLDRKPILAPGEATYVLYFEFVDMPARTKKSEMTRDHEAVSGSSSSSVARPQRRLKDDGKPGAMNHKHLAKLISRRNELFTKAVNSFIDKHTHLGEDPAEALQRESRNYIPRTPEPATLVSKSEYQDTIPAKIPTDRNSFAEIIRELKASSWYLDQVMPDGHFTTMPKEPEYGDLEFLLSQTLVDAIYNARGITQFYSHQAQALNALHSGHNVVVSTSTSSGKSLIYQLPVLYDLEKDSETRAFYIFPTKALAQDQRKSLAQTLSFMAGLEHTVVETFDGDTARHVRDDIRENASVIFTNPDMLHVSILPQHQSWGHVLKHLRYVVVDELHYYDGQMGAHMAFIMRRLRRICALHGNTSVKFISCSATVSNPVQHFQRIFGLCDVTLVSQDGSPEPLRHHLLWNTASPALAAAGAEDPSYVLGEVARVFCALLLRGVRLLVFCKMRSQCEQLLNAIKNELTNLGRAESTALVMGYRGGYMVQDRRRIEADMFSGQLRGIIATSALELGVDMGSLDCVISWGFPHSLANLRQQFGRAGRRAHSGMDALAILVGDRTAEDQYYMENAAELQMPVTAELWSDLGNREIFEGHLNCAAFEEPVDIAGDIDYFGKDLPVVLASSPVDGNWDRNGNKDWEDKEDKACGCPRPLAEDGKVPGKFHPRQVFWPYPAKRVSIRAIEEDMVSVVDLTNGSFVVLEEMELSRATFALFAGAVYLHQGQAYTVKEYNAKERIAKVEYMKTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIT6</accession>
    <name>A0ABR3YIT6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_006390</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000292">
        <property type="protein sequence ID" value="KAL1887865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF30">
        <property type="entry name" value="MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="356"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="281"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="73"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="149"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="283"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="693" mass="76073" checksum="FFAD9776AC2D0D35" modified="2025-10-08" version="1">MDSHPATTRPQKFDTTASLCPSSPGSDSVSKMSSCVASNEHDDHDKNFIPIRPQPVQFRSNTIAPSPTLPQAEFTTIPTSPVLSTSAPRSPSQLRLVTDTHGVTHQSPPRSTDNIHSNPGSLRINTKKSTTTLRSIARTPSLKASIARPFSGPSGSSPASSFAASPVIAAMGDVTPLPSPLLYHDSSGPWSGISGRPPSRDVLPIPQSDAVLVSAEGESIDTALANSERRKSYAALGLRRDSLNVAQNPANVKEYHTRNRSLSEFTPDPVAIPKRMVTVSGPHGREVKDASKRHMRRETNFAESRGLTPTCEQPPTPPSSETSKSSIDGAIDGKAKGPAAEYFEAYGRIDGKKRRWRAVKTLGQGTFSRVVLGTSQIDIDDATLLLMDSNTVEVRLDRKTLVAIKVCEHGPRGGASEDRIEMSLKRELEIMKIIRHPSLVNLKAFNLEMTRAILVLTHCPGGDLFDVATTNHNALKPALLRRIFSEIVGAVQYLHQNCVVHRDIKLENVLVNLRPSELANPGINWKTYPYSVITVTDLGLSRQIADDEKLETRCGSEDYAAPEVIMGQPYDGRATDAWSLGVLLYALIEARLPFDPHPGVSDFHRMRSRTSHRIARVEWRWVKYEGEDGDHEASIAKFTEVDMLGAMEITEGLLKRARSRWTLQQVADNPWVEDALQIPGGLQYREELEGQEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIV3</accession>
    <name>A0ABR3YIV3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="3">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MSC7</name>
        <name evidence="8" type="ORF">Cpir12675_006244</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000270">
        <property type="protein sequence ID" value="KAL1888248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="7">
        <location>
            <begin position="89"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="614" mass="65925" checksum="19D7EA7191DA0AFF" modified="2025-10-08" version="1">MDAVPGPVLANPARDFILALGEAVQNWLETNFPGIRFELFSAIIGTLFALVCMYLLVSGEEDPIRYRVPPPKMPSQDRTVDETTIVAPGSTAIQCYAPATAHFLGFINPSTSASIDRAIESATSAQKVWAKTTFRQRRAVMRTLLQHVLDNQEQICRIACLDSGKTMLDAQLGEIMVTAEKLSWTLKHGEAALTSSRRPTNLLLMYKRNEVRYEPLGVVSALVSWNYPFHNFIGPVISALFAGNSIVVKVSEQTAWSSMYFTNIVRGALVAHGHDPALVQTVACWPAAAGHLTSHPGIAHLTFIGSKPVCHQVAAAAAKSLTPLVAELGGKDPFIVTASAKRDLDRIVEIALRGTFQSAGQNCIGIERIIVVPELMEAFVSKVTPRVQALRLGPEADIGAMISDVSFTRLEGLVADAVLKGATLVTGGKRHVHPDYPKGHYFQPTLLVNVTPGMKIANEECFGPIMTVMSTHDSSAESILAIANAPAFGLGASVFGKESDPVVQAVVDGVRSGNVAVNDFATFYAVQLPFGGVGGSGYGRFAGEEGLRGLCNAKSVCIDRMAWMGVRTSIPPKVQYPVANQDKSWAFVKGIVEMGYSLTVGRMMGGLATIIKNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJC3</accession>
    <name>A0ABR3YJC3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">B(0,+)-type amino acid transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_006317</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000281">
        <property type="protein sequence ID" value="KAL1888060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050598">
        <property type="entry name" value="AminoAcid_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785:SF402">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="431"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="455"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="490"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="517"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="409"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="409"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="419"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="543" mass="57795" checksum="53A7403BE4763CCC" modified="2025-10-08" version="1">MPDLDSEAQQPLLAEPQLAQQTYDAPPYGTTTRITRPDSDRDISGPQPTLGAIEAFGILISIVIGSGIFTSPGSIDTNVPSPGASLVVWLVGGLLAWTGASTVAELGTAIPGEGGVQPYLQYIYGDVFGFLAAWTWTVAVMPATLAILSIVFVDSIFSALNAAPAVFTLTADSMWFIRKSLSVAILMLVSLANCISTKASTRLNNFFVVAKFASIAFVVLAGLAVVVVQVAHGTEPIEAGGHDWFQKPWFAARTSMNPDGSETDWTRLSQWELLGHYSAALYGALWAYSGWDKAVYVSAELRDPVRQLPLAINTAIPTIIFAFIAAISSYYVLLPWNEVSTTDSVAVTAIARLFGPGIGLVASVMICLVVAGSLLGNSFVAGRMAMSAAHKGWFPHCFGTVGRLSLPSSGTSTLQANSGHDRSNRENTGDAPINAIGLATLLAAFYIVFGNFRALITFNGLGEFTFFFLTVVGAVILRLREPSLNRPYKLPLAVPVIFSLVSGFVVARGAIFAPAQAAMLLVLWALGVAYYLVCQWRAASVHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJN2</accession>
    <name>A0ABR3YJN2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA(Phe) 7-[(3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4)]-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.282</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_006137</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = 7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36635"/>
            <dbReference type="Rhea" id="RHEA-COMP:10378"/>
            <dbReference type="Rhea" id="RHEA-COMP:10379"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73543"/>
            <dbReference type="ChEBI" id="CHEBI:73550"/>
            <dbReference type="EC" id="2.1.1.282"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TYW3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.282" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000257">
        <property type="protein sequence ID" value="KAL1888516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1960.10">
        <property type="entry name" value="tRNA wybutosine-synthesizing-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003827">
        <property type="entry name" value="tRNA_yW-synthesising"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036602">
        <property type="entry name" value="tRNA_yW-synthesising-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48418">
        <property type="entry name" value="TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48418:SF1">
        <property type="entry name" value="TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02676">
        <property type="entry name" value="TYW3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111278">
        <property type="entry name" value="SSo0622-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA wybutosine-synthesizing protein" evidence="9">
        <location>
            <begin position="14"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1888516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="297" mass="32190" checksum="F0488983BA75DE2D" modified="2025-10-08" version="1">MNPLPPPPVSFAAKKAKLLEGLQVPDEEYTDLSPKGSVDIGIRPLIRDINCIDGLVTTSSCAGRVSVFVEGRKKSSAPATREADIVTELWRGEETDTEVVRPDAKTLAAVGGKGGGGTWLFVSHDPVHKGNSDWRSILGLQGPQTDKARPASGDERLVHFKFEPMILHILTASPAHAQLVLRCALQAGFRESGSLNIMPDAASGAVTPMVAVRSMGLSFESLLGHWRDGGSAEAGEITLYVPEDYLDIIMNLANERFVENARRIERFRNAFLNTFNDVGAAKKKKKGQEGAEWEDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJQ9</accession>
    <name>A0ABR3YJQ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000263">
        <property type="protein sequence ID" value="KAL1888404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="115"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="327"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="473" mass="51729" checksum="C6727A2D9186883B" modified="2025-10-08" version="1">MAPHHIVAGQENLSGAYGSAQHTPYSSQYPHHAPPSFHFSSYGPQMPLPSHPPPMAMPQGHSIVPYHVSQVQPHKHGSPASSRSHINKSSKPLPPAPSSLPAKPPGLPAKPPPAASSSIHHSSPSPSGFKPPMAAILNHKGAWNGNGHNNGSNDRPWKKHGCRKKKDSFQKQPKPEINVEAALIPAVTATPITDANTSDIEEGEISMESSPVTSNLTMSKTAVNDCDKSEGEIDEEDVSQIKNIAHGLPWGKSTTTGLDGRRGSDSHERSQDNSSTTPSSILSDRRQQNLPSRIPGDRGRGRSRSPVSQSRLHKQSFGQRTSNDMRQPTSTTVSSTQQTYHSHQSPRDSRDSCRESSQVSTQSRNARHRDSFSDSNSRHTEESRYRSRSPITPRGDYKRHNLDNDAASDEDEELSEFESAILGRERSPKAKPHGRSTSATKSGFKIPKRCRATVESRRREDNVYGYVNSNLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJU2</accession>
    <name>A0ABR3YJU2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000254">
        <property type="protein sequence ID" value="KAL1888576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="386" mass="43165" checksum="366C070AE671AF36" modified="2025-10-08" version="1">MSMVPQSWRSPAQDHGSLMRGGRGSIGSANVSWENEIESHPQSAIINVPHFQSRICPFAHYNPIKYNRSEWAHCHNPQEKNGDIVVHLQRHHRLIRSQRKPDKTGRKNGNGQSYIAICSGENFNDRGDSQCHECESFEGIVDSSSRRDDWNSRLHRISAICQKCWCILRNRTELATHLQTNCGGRSPKHLEKWQLELEAFCINPDWIEPPPHGATQSPLMTSPPPDLHSSIPSHAPINVPVRGNVGALTSGDSVNNTHGDALTQSHQTRIKPISNEMAYSDTAMIESYKAEIEKLRLHLYFLVNHPRTAVSQSIQQLYHDGNCYSVDITPPRKLDPRIEPPGIQWTPPYALITGPGMASSAYMPMGPGPNNESSEYMGPPSTHPGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK47</accession>
    <name>A0ABR3YK47_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000266">
        <property type="protein sequence ID" value="KAL1888330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="165" mass="18800" checksum="5E34AC84F4301A6E" modified="2025-10-08" version="1" fragment="single">MAGSRKSGSVKTGATTRTAASRTARRYISHHHQYRWPGFLLNIWILIMLLSSSACLGILANFVVIQNRLKLGIPWYLPYFITVSCLTLVFIFILVWLTWKRRLLPAIVMIGAFVLFLMWMVGLVRISMALWGSGSVNSQCSIQVFSQDPKGENMRTLAWMMQRSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKP8</accession>
    <name>A0ABR3YKP8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12 13">Homoserine dehydrogenase</fullName>
            <shortName evidence="12">HDH</shortName>
            <ecNumber evidence="5 12 13">1.1.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">HOM6</name>
        <name evidence="17" type="ORF">Cpir12675_005995</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-homoserine + NADP(+) = L-aspartate 4-semialdehyde + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15761"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.1.1.3"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:15763"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:25213"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 3/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 12 14">Belongs to the homoserine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.3" evidence="5 12 13"/>
    <dbReference type="EMBL" id="JAWDJO010000240">
        <property type="protein sequence ID" value="KAL1888906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004412">
        <property type="term" value="F:homoserine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005106">
        <property type="entry name" value="Asp/hSer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011147">
        <property type="entry name" value="Bifunc_Aspkin/hSer_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001342">
        <property type="entry name" value="HDH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019811">
        <property type="entry name" value="HDH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022697">
        <property type="entry name" value="HDH_short"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43070:SF5">
        <property type="entry name" value="HOMOSERINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00742">
        <property type="entry name" value="Homoserine_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03447">
        <property type="entry name" value="NAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036497">
        <property type="entry name" value="HDH_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01042">
        <property type="entry name" value="HOMOSER_DHGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12 13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 12 13" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="8 12 13" id="KW-0521">NADP</keyword>
    <keyword evidence="9 12 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12 13" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Aspartate/homoserine dehydrogenase NAD-binding" evidence="16">
        <location>
            <begin position="11"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Homoserine dehydrogenase catalytic" evidence="15">
        <location>
            <begin position="153"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR036497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF03447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1888906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="362" mass="37715" checksum="366A0F9991A9F348" modified="2025-10-08" version="1">MVNNVLIAVIGAGGVGKCFLGQLATLAARRPSPKLDLCYICSSKKAVFSTDYASIDINGATETLAASSVAPKSLTALADYLAAAPSKVVLVDNTSSQDVADSYPLFLGKGVSIVTPNKKAFSGSYDLWKAIFSASEASGAKVYHESSVGAGLPVISTLKGLVDTGDKVTKIEGVFSGTMSFLFNSFAPTEGKGGQWSAEVKNAKALGYTEPDPRDDLNGLDVARKLTILARLAGLPVASPTAFPVQSLIPTELESCTSGDEFLEKLPAFDSKMEATKSEAEAEGKVVRFVGSIDVATQNVKVGLEKFDRSHPIAALKGSDNIISFYTERYGSNPLIIQGAGAGGEVTAMGVTADLINVIAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLU4</accession>
    <name>A0ABR3YLU4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Importin subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cut15_2</name>
        <name evidence="8" type="ORF">Cpir12675_006037</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the importin alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000243">
        <property type="protein sequence ID" value="KAL1888810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032413">
        <property type="entry name" value="Arm_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024931">
        <property type="entry name" value="Importin_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23316">
        <property type="entry name" value="IMPORTIN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00514">
        <property type="entry name" value="Arm"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16186">
        <property type="entry name" value="Arm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005673">
        <property type="entry name" value="Importin_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="ARM" evidence="6">
        <location>
            <begin position="39"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="6">
        <location>
            <begin position="81"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="6">
        <location>
            <begin position="250"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="427"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="436"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="449"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="466" mass="50358" checksum="94C9D213FF051A2E" modified="2025-10-08" version="1">MVAGVFSEQIDQQIQATTKFRKLLSKERNPPIEEVIKTGVVSRFVEFLRSPHTLVQFEAAWALTNIASGSATQTQVVIEAGAVPIFVELLASLEPDVREQAVWALGNIAGDSPKCRDYVLSCGALRPLLALLGDSRKLSMLRNATWTLSNFCRGKSPQPEWPAISPALPVLAKLVYSLDDEVLIDACWAISYLSDGSNDKIQAVLEAGIPRRLVELLTHASTSVQTPALRSVGNIVTGDDVQTQIIINCGALPSLLSLLSSTKDGIRKEACWTISNITAGNSTQIQSVIDANIIPPLVHLLQNGDLKTRKEACWAISNATSGGLQKPEQIRYLVSQGCIRPLCDLLACPDNKIIQVALDGLENILKVGDLDKQAAGTGPESINRYALFIEECGGMEKIHDCQNNANEEIYMKAYNIIEKYFSDEDENADEAGAPQATGANGTFGFGTTDQQSGGFNFASTGDSMDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMP7</accession>
    <name>A0ABR3YMP7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_005707</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000209">
        <property type="protein sequence ID" value="KAL1889626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46283">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE MARCH5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="26"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="266"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="555" mass="59140" checksum="AADD17CD5FC3FE81" modified="2025-10-08" version="1">MASERPLLPATDPSATADAGDSTPRCFICLMDDDDDVPRPPDSASDWVYPSPCSLAAHQDCIMAWVQDCEREGRALQCPVCKEAISVDQPWDPVLSIAAACTSRARTLAPSILAGMVGSGTLASMGIYGAAAMTVFAGRGAPFRFVHVVDGGQAHLSLTRLAVLPLIGPALVMGYSFGLVTVPISLPMFGVYGSYLLGNDPGAFSWPPSPQAAMVFFPYLQALYRAIYRELCHDWEKQLDERISGLPEALIDDPPAVAVVAEPPVPQAHEGQPQEPGQNAEDAHDQAQDGNRGGVFAFFREAMEIFNANYDLEVVVEEGIIDDNAPLVDAEINVNGVGVGWQIPGLGANERPMPLPAMVGNPARLVAPLEDPWADAGQALAVVHNEAPAAAPVPAMAPVPDMVPAVPIVEPIADLVPAPAPALAPAPAPAPDPPALPQRGIRASLSDICLNVVTALLMPGISFTAGEILRLLLPRRFTMMPRVPSWTGPRYEQTGFLQTKWGRSLVGGCLYIVLRDAVRLYVKYRQSLLQGHRRVRNVKRGLPGAPVVVPVHQGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMU2</accession>
    <name>A0ABR3YMU2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Hydroxymethylglutaryl-CoA synthase</fullName>
            <shortName evidence="3">HMG-CoA synthase</shortName>
            <ecNumber evidence="3">2.3.3.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">3-hydroxy-3-methylglutaryl coenzyme A synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ERG13</name>
        <name evidence="6" type="ORF">Cpir12675_005792</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>acetoacetyl-CoA + acetyl-CoA + H2O = (3S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10188"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43074"/>
            <dbReference type="ChEBI" id="CHEBI:57286"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.10"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the thiolase-like superfamily. HMG-CoA synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.10" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000216">
        <property type="protein sequence ID" value="KAL1889457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004421">
        <property type="term" value="F:hydroxymethylglutaryl-CoA synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00827">
        <property type="entry name" value="init_cond_enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000590">
        <property type="entry name" value="HMG_CoA_synt_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013746">
        <property type="entry name" value="HMG_CoA_synt_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013528">
        <property type="entry name" value="HMG_CoA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010122">
        <property type="entry name" value="HMG_CoA_synthase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01833">
        <property type="entry name" value="HMG-CoA-S_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43323">
        <property type="entry name" value="3-HYDROXY-3-METHYLGLUTARYL COENZYME A SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43323:SF2">
        <property type="entry name" value="HYDROXYMETHYLGLUTARYL-COA SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08540">
        <property type="entry name" value="HMG_CoA_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01154">
        <property type="entry name" value="HMG_CoA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01226">
        <property type="entry name" value="HMG_COA_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hydroxymethylglutaryl-coenzyme A synthase N-terminal" evidence="4">
        <location>
            <begin position="11"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Hydroxymethylglutaryl-coenzyme A synthase C-terminal" evidence="5">
        <location>
            <begin position="133"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1889457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="405" mass="44273" checksum="F5B7E63027FDB6CA" modified="2025-10-08" version="1">MPGLTDEPQFADIYSMALTVVSNLIKKNNIDVNNIGRLEVGTETLLDKSKSVKTVLMQLFGENTDIEGVDTVNACYGGTNAFFNAVNWVESSAWDGRDAIVVAGDIALYAKGNARPTGGAGIVAMVVGPNAPIVAEPGLRGTYMEHAYDFYKPDLASEYPYVDGHYSLTCYTKALDAAYRAYCKREAKQAAADASKPTLDRFDYMCFHAPTCKLVQKSYARLLYHEYLANPESASFAEVAPELRDMDYTKSLTDKAVEKTFMGLTKKAFQEKVSPAIQVATLCGNMYCGSVWGGLASLLSHVEPASFAGKRIGLFSYGSGLAASFMSFRVVGDVSPVAKALDLKNRLAQRRAVAPETFDAMCELRHKAHLQKNFTPVGDESTVAPGTYYLEHVDDMFKRSYKVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNU1</accession>
    <name>A0ABR3YNU1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005738</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000212">
        <property type="protein sequence ID" value="KAL1889545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007175">
        <property type="entry name" value="Rpr2/Snm1/Rpp21"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04032">
        <property type="entry name" value="Rpr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="254" mass="27616" checksum="621FA2B7C32D19C2" modified="2025-10-08" version="1">MAAKPVPGLQERLNLLIDSSYMLATSSPEISAYFMRQRNQLLSDYGITIPEVDKHRICGACSSVLALEAVADVRIETGVRHVKAQRRTEALERKRALARDKTKGGNRTVRSEAGDKECRKTTSNTSQKRTEVARVGVSKITKCHRCSSFTKSQIALPPVSLRFKPAKWRKKKGKGKSKASNDNTAGGIAPKKTLLADETQTVTGTIPSAENKNAVSSTAPGKKRKKTKNGGLQALLAQQKKPAGGLSLADFMKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQJ5</accession>
    <name>A0ABR3YQJ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_005495</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000190">
        <property type="protein sequence ID" value="KAL1890202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046579241" description="Cytochrome P450" evidence="7">
        <location>
            <begin position="28"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="273" mass="30547" checksum="8D04689A4DA342F9" modified="2025-10-08" version="1">MMVAGHETTANALHFMLLYLAAHPAAQRSLVRDLDDIIGSKSPENWDYDTMLLPLLNSHAGACMNEVLRMMPSVTMIPKIVTPDAPQSLTLDGTTHVVPAGTQILISAFSAACNPKFWPTQPSRVTGQPHDMDDFLPEEEQGIEEVKDDIIDNKALGMYRPVPGSYFPFGEGARSCLGRRIAQVKMMATLAVIFQHCSIELAVDEWATDIQIDMMDQEARRSVYKQAQDKFEDTMTQCISIITLKLHGAYVPIRFVERGNERFVNFLADEEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQK7</accession>
    <name>A0ABR3YQK7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Multicopper oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_005510</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000192">
        <property type="protein sequence ID" value="KAL1890171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13857">
        <property type="entry name" value="CuRO_1_Diphenol_Ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13910">
        <property type="entry name" value="CuRO_3_MCO_like_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF414">
        <property type="entry name" value="ADR239WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Plastocyanin-like" evidence="10">
        <location>
            <begin position="69"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="8">
        <location>
            <begin position="195"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="9">
        <location>
            <begin position="469"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1890171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="625" mass="70420" checksum="76AFE0DE3B63B21E" modified="2025-10-08" version="1">MHTPTSTSISLPGHGSSSGDSDSKVEYQYHETTPPTAQLRNMEEYIIDPAWDYSLSPAVREYFWVINDAELNPDGVFRPMVLINNQFPGPLIEVNSGDNIVVHVDNRGINATSIHFHGIFQNGTNAMDGTVGITQCPIAPGTTYTYNFTVSGQSGTYWYHAHYGSQASDGVFGPMVVHAANEKTELQKLDYVSDRVVMVHDHYHDTTAQILMDYLAPGRENDEPVPESAMINGRGVRNCTEFPDRKCDDSSVGFPDIQLQKEARHRLRIINTGAFGTFQLQIDEHPFYVTEVDGMDVFPEDFHRLEIMPAQRYSLIVEANSTVSDEFWLRARFVTHCFSYDNPYMKPNIEGIVRYVDASPSSRPPSPLSSTLTALPTPTTSDWADMEVFCKDLESLMLHPVTKPTIPQSDNYIQLKASFRIGDWTLSRGFINTTTWHTNISHPSLHRLLDALPAKQELLPGGSPLNGVNDRLFDLDREFVFQTRGAQTLDIAINNFDDGAHPFHLHGHKFWVLTESTTGYPPDKHALDEFLQSTNALDNPVMRDTVTVQAYQWALIRVTLDNPGIWAFHCHNMWHAEAGMVMQFLVMPEELMLNSGVGQKERELCQRPGIEKGMRPDDSIWEGII</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQL8</accession>
    <name>A0ABR3YQL8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">General negative regulator of transcription subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">NOT5</name>
        <name evidence="15" type="ORF">Cpir12675_005455</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes. Preferentially affects TC-type TATA element-dependent transcription. Could directly or indirectly inhibit component(s) of the general transcription machinery.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the CNOT2/3/5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000187">
        <property type="protein sequence ID" value="KAL1890285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1020">
        <property type="entry name" value="CCR4-NOT complex subunit 2/3/5, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038635">
        <property type="entry name" value="CCR4-NOT_su2/3/5_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012270">
        <property type="entry name" value="CCR4-NOT_su3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040168">
        <property type="entry name" value="Not2/3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007282">
        <property type="entry name" value="NOT2/3/5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007207">
        <property type="entry name" value="Not_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23326">
        <property type="entry name" value="CCR4 NOT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04153">
        <property type="entry name" value="NOT2_3_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04065">
        <property type="entry name" value="Not3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005290">
        <property type="entry name" value="NOT_su_3_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0010">Activator</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0678">Repressor</keyword>
    <keyword evidence="8 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 10" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="CCR4-Not complex component Not N-terminal" evidence="13">
        <location>
            <begin position="3"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="NOT2/NOT3/NOT5 C-terminal" evidence="14">
        <location>
            <begin position="540"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="236"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="349"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="456"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="131"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="243"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="275"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="359"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="388"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="409"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="456"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="469"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1890285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="668" mass="73685" checksum="968F58F4249EB734" modified="2025-10-08" version="1">MAARKLQQEVDKCFKKVAEGVAEFEAIYEKIEQSTNPAQKEKLEDNLKREIKKLQRMRDQIKTWAASNDIKDKTPLLDHRKLIETQMEKFKAVEKAMKTKAYSKEGLSAAAKLDPKEKAKEESGAFLREMVGSLELQVEALEVESESLSATIKRGKNNASKAERISEIEDIIERHKWHQGKLELIRRSLENGGIETEQVTDLEESIRYYVQDNSSPDFIEDEELYDDLHLDADEDNFGMNLADNDKGSSQDTQSIHDDGPTPGEAIIESLKAGSKNRSAETSNKRQVSAQLKSPLPTLATLHPPQPSSSASSTAIMKPASVPTRLAGEGLKYASAAAAAAANDKNNVGIAPLPPPPGSVPLKSSATSSPAVSVSHPVTEPTKSHSEASSKGINSAKSTPKTVASRLAKSVTSVSNSVSDAVEPSIATSSTASPPPAAVTGSLEKVPIQLLAPATTASASAPTSTQTPAVQSAQVTNGVSTKSSNKATGSTTASRVEEESIYHLPASLQDLLETYEATKARPMAANSPATQRLLEASHREAPKAMDSEMAKHYTPEIPMSSPSTNYPMQPLDILDNPRLYSRLETDTLFYLFYYRQGTMHQYMAARALKDQSWRFHKQYQTWFQRHEEPKNITEEYEQGTYRFFDYESTWMNRRKADFKFTYKFLEDDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR76</accession>
    <name>A0ABR3YR76_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Serine hydroxymethyltransferase</fullName>
            <ecNumber evidence="8">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SHM2</name>
        <name evidence="10" type="ORF">Cpir12675_005335</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Interconversion of serine and glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the SHMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000179">
        <property type="protein sequence ID" value="KAL1890582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049943">
        <property type="entry name" value="Ser_HO-MeTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000586">
        <property type="entry name" value="PRK00011.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680:SF28">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Serine hydroxymethyltransferase-like" evidence="9">
        <location>
            <begin position="20"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="479" mass="52522" checksum="C53DFB9253196FC0" modified="2025-10-08" version="1">MSAYALSNDHKDMLEKSLLDSDPEVATIMKDEIQRQRESIILIASENVTSRAVFDALGSPMSNKYSEGYPGARYYGGNQHIDQIELLCQKRALAAFGLNGEKWGVNVQCLSGSPANLQVYQAIMPVHGRLMGLDLPHGGHLSHGYQTPQRKISAVSTYFETMPYRVDLETGIIDYETLAKDAILFRPKVLVAGTSAYCRLIDYKRMREIADSVGAYLMVDMAHISGLISAGVIPSPFEYADIVTTTTHKSLRGPRGAMIFFRKGVRSVDAKGKETLYDLENPINFSVFPGHQGGPHNHTITALAVALKQASSPQFKEYQQQVVSNAKALENKFKSLGHKLVSDGTDSHMVLIDLRQHSLDGARVEAVLEQINIACNKNSIPGDKSALTPCGIRIGTPAMTSRGFGTADFERVGQYIDDAIKICKETQAALPKEANKLKDFKAKVASGEVSRINELKAEIAAWTSDFPLPVEGWRMDAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRI2</accession>
    <name>A0ABR3YRI2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">protoporphyrinogen oxidase</fullName>
            <ecNumber evidence="5">1.3.3.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">HEM14</name>
        <name evidence="14" type="ORF">Cpir12675_005288</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>protoporphyrinogen IX + 3 O2 = protoporphyrin IX + 3 H2O2</text>
            <dbReference type="Rhea" id="RHEA:25576"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
            <dbReference type="EC" id="1.3.3.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrin-IX from protoporphyrinogen-IX: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.4" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000176">
        <property type="protein sequence ID" value="KAL1890687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004572">
        <property type="entry name" value="Protoporphyrinogen_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050464">
        <property type="entry name" value="Zeta_carotene_desat/Oxidored"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00562">
        <property type="entry name" value="proto_IX_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923:SF3">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="13">
        <location>
            <begin position="127"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="61"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="66"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1890687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="710" mass="79169" checksum="8E921468CAADDEC7" modified="2025-10-08" version="1">MRAAQLARAPLRRLVSHPGLRPIPGTCYRLALPHLPGTSLASIARSSPSFSTVRSSFPALALSKASEAEHRRQEERKLEEEEEEEEEIEDDEYDEDEDHHSYMDRHYGQLSELSETPKTIGILGGGITGLSTAYYLARENPDMKITIFEASDRLGGWMNTHTAVDPDTEMPVYIENGPKTLRSLTSTPTRADDYVLADMLISLGVHPCVTYPGAKFVLDARPNESQEDDEYQISHLLRIPPPLLMKQLLHPAWKGWAKSVLAFWILMLKVRFGLVKPPTTSEDMTVAEWLRSLGIGKEHNAPMLESMLSAMAHGIYGGDIEKLSVQSFLSTRFFQLYRQNQPNESRMIPVQDLQIMQELGDDQAVVDYIKYMGLGESLVFPGGMQTLIGALENALKTQPNITILKNEKATLLEFDKENDNMKVKSASQTTGTTMERTFDKVVSTIFSSQLASIVPCDEKSGISCLPTLQGQKAVSVLNVCFYFDRKLDLPHDYTGVLPLPSVKGPVLGVFVDSNLQGPNTETHIRAHEAPGTKLSVLVGGHHWQRFSRQELDTMQTMGEDKARQFLRNFLSISETPTITHSFVAHECIPQHYKGHRATMADAHWDLMENFKGRLAVAGGSYTSIGVLPSIRAGYCIAQQITNFSEADAPEYDYTGLTGLAQFIREEQFADVEDEALAKFGKKTQYTVQDPDALERFKHLVSKISSSPVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRI9</accession>
    <name>A0ABR3YRI9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Sexual differentiation process protein isp4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_005169</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000166">
        <property type="protein sequence ID" value="KAL1890979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="299"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="371"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="448"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="501"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="527"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="553"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="611"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="682"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="706"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="728"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="756"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="74"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1890979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="821" mass="92410" checksum="5FC3BB22D50BD7A6" modified="2025-10-08" version="1">MPSFFRRRHEPEDITPHLGPVDHAEASGLEHLTDVTAYDQAEKKDSTLKVDHFNSLDPNLPLEKLTELDSALASGTAEKGDVKDKCGNVKTGPAGLHDSQDSSPYPEVRAVVRDYDEDLPANTIRAWVIGLLLCTLGSGVNMLFSLRNPSVTITTYVVQLVAYPIGRGWDLIFPDRVWSIFGVKFNLKPGPFNYKEHVIIVVMSNAAYGGGALYATDVLIAQELFYGQHFGWAFQLLFGITTLCTGYGLAGLARRFLVWPASMIWPSNLVNCALFYTLHDHAPADPARTSGWKIPRFKLFLIVFTCAFVWYWFPGWIFQGLSYLTWICWIAPDSVIVNKLFGGYSGYGLFPISLDWTVISGFIGSPLIPPFHAIANVVGGIVIFFVFLSMGLHFSGTWYSDYFPVQSSLSFDNLGLEYNVSRILNSKFEFDETAYHAYSPIFLPTQFALSYGLSFAAVTAVIVHVWLYHGTEIWKQFRLARHQEDDVHMRLMKKYRDAEDWWYVALFLVMFGLSLGVVAGWPTGFPVWAFFVCLLIPILWLLPIGIVQAISNIQLGLNVLTEFIIGYMVPGKPLTMMMFKNYGYVCMGQALFFAQDLKLGHYMKVPPRVMFSSQLVASVWSAIIQIIVMNWAFDHIPNLCDAKQENHYTCPGGRVYYTASVVWGAIGPARIFSSGAMYSGLQWFWLVGALAPIVTWLLARRWPHSVWRYVSAPLIFGGSGWLPPASVYIYLCWGIVGTVFNFYIKRRYTGWWLQYNYIVSAALDCGLVVATLVIFFTLYLTSAAHPQWWGNLGAMETRDYLETAVSSKVAEGQIIGLAQWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS01</accession>
    <name>A0ABR3YS01_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">5-formyltetrahydrofolate cyclo-ligase</fullName>
            <ecNumber evidence="5">6.3.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_005095</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(6S)-5-formyl-5,6,7,8-tetrahydrofolate + ATP = (6R)-5,10-methenyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10488"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.2" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000162">
        <property type="protein sequence ID" value="KAL1891126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002698">
        <property type="entry name" value="FTHF_cligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23407:SF1">
        <property type="entry name" value="5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23407">
        <property type="entry name" value="ATPASE INHIBITOR/5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01812">
        <property type="entry name" value="5-FTHF_cyc-lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006806">
        <property type="entry name" value="FTHF_cligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00036539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="233" mass="25802" checksum="B598A9D73997A7D6" modified="2025-10-08" version="1">MSSPTLVLAKQKLRALVRESLQKIPHESVISQSNAIFETLRGLSPYINATSISIFLSMPTGEVQTREIVKDALQSGKTVYIPYLHNTPPHLECTPKRVMDMVRIRDLEDYESLQPDKWGIPSVDPVSISTRNRILGETTEKINPVTLDMVLVPGLAFDTNSGGGIKRMGQGRGFYDLFFERYAAELSKTPVTLCGLGLEEQFLPNMLQASELPVGPQDKLLNMLILGDGSITQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSD3</accession>
    <name>A0ABR3YSD3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase</fullName>
            <ecNumber evidence="9">2.7.4.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">VIP1</name>
        <name evidence="13" type="ORF">Cpir12675_005043</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>1D-myo-inositol hexakisphosphate + ATP = 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:37459"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="ChEBI" id="CHEBI:74946"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:37460"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ATP + H(+) = 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:10276"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58628"/>
            <dbReference type="ChEBI" id="CHEBI:77983"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:10277"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
            <location evidence="9">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the histidine acid phosphatase family. VIP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.24" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000159">
        <property type="protein sequence ID" value="KAL1891226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013651">
        <property type="entry name" value="ATP-grasp_RimK-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037446">
        <property type="entry name" value="His_Pase_VIP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040557">
        <property type="entry name" value="VIP1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12750">
        <property type="entry name" value="DIPHOSPHOINOSITOL PENTAKISPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12750:SF9">
        <property type="entry name" value="INOSITOL HEXAKISPHOSPHATE AND DIPHOSPHOINOSITOL-PENTAKISPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18086">
        <property type="entry name" value="PPIP5K2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08443">
        <property type="entry name" value="RimK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="VIP1 N-terminal" evidence="12">
        <location>
            <begin position="335"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp fold RimK-type" evidence="11">
        <location>
            <begin position="559"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="179"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="276"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="693"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="759"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1072"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1119"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1266"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1469"/>
            <end position="1522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1620"/>
            <end position="1657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="9"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="305"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="318"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="713"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="760"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1121"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1268"/>
            <end position="1301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1472"/>
            <end position="1490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1491"/>
            <end position="1512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1637"/>
            <end position="1652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF18086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1891226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1778" mass="192956" checksum="0BBD6E28E3A5DE4C" modified="2025-10-08" version="1">MEHQKETTEPEIEPEMESETETENELDHFEDAKESLPDTNNQSLLPDITAAITTATTTTVAAPEPAVFLDEAGIKKTEGEDFSSAPHFNTDSFAAASSPVCPIATVDSAIFDPATSGAVASGTSASAAIGSSYLANSVSVDQQQSPLSLPLSSGILTSIDKTTVSPLLAPEAIDPAPLGTITATSDNTSLQPLPLTPPLVSAMPEPSDAPPASRASLSEFSTKRASISSIYSLASARGIPSSAASANGSESGIKTAPPGTSAAVITAQNHIVGHDAVGKRASNQRLEINIRQPGSGRERSRANRRFSASTSASSHSPSSDRPHQKEELKPAAWGTIGVCALDVKARSKPSRNILNRLISNREFDIIVFGDKTILDEDVENWPLCDYLICFYSDGFPLDKAIAYVKLRKPFCVNDVSMQKLLWDRRLCLQLLNKIGVPTPSRVEVTRDGGGTILTPELRKQIKETSGIVIEPMESEPTPPPTSVELIDNGDAISVDGAVLYKPFVEKPTSGEDHNIIIYYHSSVGGGARKLFRKIGNKSSEYIPGLNTPRAITEPYSSYIYERFTKVDNAEDVKAYTVGPTYCHAETRKSPVVDGIVRRNTHGKEIRYVTSLTSEEKEMASKISRIFGQKVCGFDLLRASGKSFVIDVNGWSFVKDNDDYYDHCSTIMKELFIKERIRRAGSISAISSDPSARSRAYSISGRDRDSAVASSDHAGSIASGEKSSSQSESIHRSGSMSATVADSSASIKSVKGVSIDETRTSSACHSAISSHAEGECVDGEATEDTTPPPAAPVKSPWKLKGMVSVIRHADRTPKQKYKFTFHTEPFIDLLKGHQEEVLLIGEAALSSVRHAVDRAMAQGIEDQAKLKLLQTVLIKKGPWPGTKVQIKPMFRKKKTDSTPTSPLPEPPSIIKEGVANDFGPIPALAASPSKSSPTLVPTTVGRGHECRTHRQDSLSGVTMSRITAAEDGLVLDKLQLIVKWGGEPTHSARYQAQELGSNMHNDLALLNREVLDEVHIYSSSERRVTTSAQIWAGAFLGQQKLPEGLITIRKDLLDDSNAAKDEMDKVKKKLKGLLREGNERPPQFAWPPKFPEPSDVQKRVVSLMKFHRKVMHNNYERLKSLNSSNTSGGNGSNTTANNHLANSAASSSGAKDTEGSTSTHGSQSSTPSSTHGYSTPTSQGIPAPASSTTKNDQKGVNFRWCCGEDADLFKERWEKLFIEFCDNEKVDPSKISELYDTMKFDALHNRTFLEWVFKPSQEMLEEEYNMASLDKEKETQEQERVRQEKEKEKVKEKEKEEEEKRNKAQQGVRRIFKRNIFNNLRHFGEAVPPRQPPPEQYFYIEEGNTQNKAKVGAEFEPLRELYHLAKVLFDFICPQEYGISNAEKLEIGLLTSLPLLKEIVQDLEEMQASDDAKSFFYFTKESHIYTLLNCILEGGIETKINRSSIPELDYLSQISFELYESEIVRKQPKHAPSHTSLVSTNAAESTASQQGAPSTTIPAPTPAPTDVVATPPSSTQADDVAAATSAMHEPAVVDEAPQFAYSIRISISPGCHVLDPLDVQLDSKHCISCAPRRSLTPHADWQEVIKTLRAKFNQVKLPKSFIAINLSEAFSLGQHHASGIKAEAEPSYGEADNHRVASNEQEVNAEGATTHSPTLKVKNSDSVTADKGELVFQDVPTNTAIGGSVTSASAAPAAAFASAFTPTPTATGTLTSSMTKPPKALESLALSVPQTSPNQQSFIDAAITAINASGEELGAGDIIAGEVDIHCHQSRPSSPSPQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSM1</accession>
    <name>A0ABR3YSM1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nuclear architecture-related protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">NAR1</name>
        <name evidence="7" type="ORF">Cpir12675_005001</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the cytosolic Fe/S protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NARF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000156">
        <property type="protein sequence ID" value="KAL1891351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.950.10">
        <property type="entry name" value="Fe-only Hydrogenase (Larger Subunit), Chain L, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050340">
        <property type="entry name" value="Cytosolic_Fe-S_CAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009016">
        <property type="entry name" value="Fe_hydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004108">
        <property type="entry name" value="Fe_hydrogenase_lsu_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11615">
        <property type="entry name" value="NITRATE, FORMATE, IRON DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02906">
        <property type="entry name" value="Fe_hyd_lg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53920">
        <property type="entry name" value="Fe-only hydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iron hydrogenase large subunit C-terminal" evidence="6">
        <location>
            <begin position="120"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1891351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="585" mass="62380" checksum="279CEEBCD15DD571" modified="2025-10-08" version="1">MSAILSVDDLNDFITPGVACIKPVETLPAVQASLEHEVVLDGTAAAASAAGPAQISLTDCLACSGCVTSAEAVLVSLQSHAEVLNVLDAAPALHIKPSNPATSSTKWIVEGLENSDAKLFVASVAPQARASLAAAMGPNFSEAQAGRVVERFLRQSLTDGGRYGNAFTWVLDTSVAREACLVLEADDVLHSGDNPLSPDIMARKTPALASACPGWVCYAEKTHPYVLPHISRTKSPQALIGTLVKTTLTRALGIPASRIYHITVMPCFDKKLEASREELTDSVWDQDSSSSSDKPVRDIDCVITTAEILTLASARGLDIFALPHSPLPPQPNFPDARISAFLLRTHTALCSPRTAGPSGGSLYFILSMAATKHSGARIIAERGRNADVVEYTLLSATGEPLLRAARYYGFRNIQNLVRRLKPAKPSMMPGGKPFGSARRRAAKPASAQLEYTYVEVMACPGGCTNGGGQIKADDTHVVQMNTANGVVDHKAWLAAVDEAYFSADETQTKAEEAAVSTNPVDGRFVQGLDTQYIREIMAYWADVTLVPLEKLAYTTYREVVSDVGKKDMSQTERAAQIAGRIGGGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTP4</accession>
    <name>A0ABR3YTP4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_004994</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TPT transporter family. SLC35D subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000156">
        <property type="protein sequence ID" value="KAL1891344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="536"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="568"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="640"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="671"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="696"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="733"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="770"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="800"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="828"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="255"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="337"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="451"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="873"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="875"/>
            <end position="884"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1891344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="907" mass="97836" checksum="024802B39DE7FABE" modified="2025-10-08" version="1">MSYPPPPGTAGSFPTVGTTNTNTNTTAGRVSHPSLPSRPPQSRASGFKTSFSKPTASAAPTSYGAPPSTYGAAPASYSRPTAQPTYGAPPSTYNAPAAPYNNAASGNYVAVSQGVRTGGSQAQGQSYGYYSQQTKNQSQSASAPASYGPVMPAGYNAAVPASDNVSAAAAAAAAEYNSAGMAAQIAQWQSAYGPKDPNAPMHPQQIGPMVPGTDAAVVGAAHGAEHQEKKKTVYREGGGKKWQDNTLIEWDPAHLRLFVGNLAGETTDDSLLKAFSRWKSVQKARVIRDKRSTKSKGYGFVSFSDSDDFFQAAKEMNGKYIQSHPVVVRKANTEIKATTVKDNRNNKWKKKNGGSKKEGTSGSGAGTKTGSTIRSIGDVPIEMNAFSRRRNSKPQTFMPSKTTTTTAAAAKSSMNTPARISPVMSTKHKPLNGSGKPHQVMSELWPDDEVDSDVGHGHGRGHSAYDAGDDLHSDEETGLTGRERSRKRALRQSNMRLDHRITGNTGGGGDDDFRGRTLSLSEEEKREADHDVLRRLAINGTLILLWYLFSLSISLYNKWMFGQGNLNFAFPLFTTSLHMLVQFCLSASVLWLVPSLRGPKGHNSDLGPVTMSRFFYVTRIGPCGAATGLDIGLGNMSLQFITLTFYTMCKSSSLAFVLMFAFIFRLEKPTWRLVAIIAIMTLGVVMMVAGEVEFSFLGFCLVILAAFFSGFRWGLTQILLLRNPATSNPFLSIFFLAPIMFTTLIIIAIPVEGFGALFNGIGELFREHGILAPLFLLFPGSIAFCMTAAEFSLLQRTSVVTLSIAGIFKEVVTICAASLIFHDTLTRVNFFGLITTMIAIAAYNYIKITSLRQEVQHKVHQDHLAAERNMHLEDEAGTETDGGPDENQFGLGSDDEEDAALLTEGHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTR6</accession>
    <name>A0ABR3YTR6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription elongation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">tfs1</name>
        <name evidence="13" type="ORF">Cpir12675_004846</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TFS-II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000147">
        <property type="protein sequence ID" value="KAL1891773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13749">
        <property type="entry name" value="Zn-ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.10">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.30">
        <property type="entry name" value="Transcription elongation factor S-II, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035100">
        <property type="entry name" value="TF_IIS-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003617">
        <property type="entry name" value="TFIIS/CRSP70_N_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035441">
        <property type="entry name" value="TFIIS/LEDGF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003618">
        <property type="entry name" value="TFIIS_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036575">
        <property type="entry name" value="TFIIS_cen_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017923">
        <property type="entry name" value="TFIIS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006289">
        <property type="entry name" value="TFSII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01385">
        <property type="entry name" value="TFSII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11477:SF0">
        <property type="entry name" value="IP08861P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11477">
        <property type="entry name" value="TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08711">
        <property type="entry name" value="Med26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07500">
        <property type="entry name" value="TFIIS_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006704">
        <property type="entry name" value="TF_IIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00510">
        <property type="entry name" value="TFS2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00509">
        <property type="entry name" value="TFS2N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47676">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46942">
        <property type="entry name" value="Elongation factor TFIIS domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51321">
        <property type="entry name" value="TFIIS_CENTRAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51319">
        <property type="entry name" value="TFIIS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00466">
        <property type="entry name" value="ZF_TFIIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="13" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 8" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS N-terminal" evidence="11">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIS central" evidence="12">
        <location>
            <begin position="152"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIS-type" evidence="10">
        <location>
            <begin position="269"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="97"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="112"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1891773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="311" mass="34163" checksum="D59BA9F6590E2A1A" modified="2025-10-08" version="1">MELRDLEQQMKSLQKALQDKEPPSVTITILEKLAKERPTEDMLRTTRAGVFIAKLRGNPNREIATAASETVNKWKSLVSSSKSKKSDIRSKAAAASAAGSSASSATGTPHNATSASAAKPAVASIHQPFKGDTEKRRFDADGAVINLTQSEVRNRCIGLLYNGLAYRSKESVARVTEIAGQVEKAIFDSHGGESASYKNRVRSLFQNLKNKSNIELGRNVMSGVISTKDFATMSHEDMKSASQREIERKLEEENMKRAQAPMAEKSVSDAWKCSKCGERKTSYSQAQTRAADEPMTTFCECMACGHRWKFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUK6</accession>
    <name>A0ABR3YUK6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cystathionine beta-lyase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_004823</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000146">
        <property type="protein sequence ID" value="KAL1891782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054542">
        <property type="entry name" value="Cys_met_metab_PP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808:SF35">
        <property type="entry name" value="CYSTATHIONINE GAMMA-SYNTHASE (AFU_ORTHOLOGUE AFUA_7G01590)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="TRANS-SULFURATION ENZYME FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="412" mass="44317" checksum="16BF614EFC261157" modified="2025-10-08" version="1">MSPQASSASKDALKAAASISTLAVHSDDGISAHRAVAPAIHVSTTFRYGLDPKDSTQWTNIDPSAPHDSHVYSRDSHPNTTRLEAVLSSILNGPAVTYASGLAAFHAMMILLNPKRIAITDGYHGCYGVIELLGRLTGLKTVPLDCDDAELQPGDVIHVETPLNPLGEARSLAYYAAKAKRTGAFFTVDATFAPPPLQDPFRYDADLVMHSGTKYIGGHSDLLCGVVAVNPKHANSSIPAAENLEARLRADRMVTGSVLGSLEGWLGLRSVRTLELRVLRQSSTATQLVQWLATAADDATSPVSKVVQRVYHASLQTGPENSWLLEQMPNGFGPVFAVICKDEKLARTLPSKLAFFQHATSLGGVESLVEWRSMSDEHAPPTLLRFSIGVEAFEDLKADLLQGFEAMIAELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVF4</accession>
    <name>A0ABR3YVF4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000145">
        <property type="protein sequence ID" value="KAL1891810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="459" mass="51103" checksum="3BBC406BA440B9B1" modified="2025-10-08" version="1">MPIQHPDDDAQPFFRALDWESAEPPVLASAPAPAPAPVPINQSEPLSPLTSPDQSGQFNPIGSINANIDVTMSSESKKSTNTANDPPSRLHATRINSIRWLLASPNAVRRMSAAYITQDQYGIPVLHLQHQISPASSVTEHSTDDPHTSRSAAGLGQENLDNDQDCGRPRNRLSVGKKEHHQSREQEVVSTYTNTYTEMSMNLPQKLAVPPPTVSSMDLITQIHDICVRATRSYLLDRLVSACARDPRTCMPYLQRQRRRSLSPGRFPGSSQLQSINARDRYRQREAPEFADRAFISAAHSGIFGASSPTRWHRRTSSESRPGAVSYNLATNISSICTLAWSQAARARLHEPQAERLAVDNMAALLEWSDHIVLAERDIWRGRSELDSQTEANLRDPERMIVGNHIGCSQVSCNNRRDYEIALREMEWRIVLSVAAAAANICMYMDDWQARGAIEALLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW39</accession>
    <name>A0ABR3YW39_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000139">
        <property type="protein sequence ID" value="KAL1892050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="182" mass="20270" checksum="B033FB3BD61ABE4B" modified="2025-10-08" version="1">MSIQIHGAEPVVTSAIPELESTAESRASDTASSSATLLTEPENPAFEDAHYEQKYRLFAFKMKKYETQQKALQSIAEFIDQTVSGNLRTFVLADKYTVKDQIAALHDRFKLSTAENNKQACEAWKKAFQTPKKQGLETWFNNLLAAHKNLTKLGLSAQSKHCYLLSALSNQLAGSNKWLVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX14</accession>
    <name>A0ABR3YX14_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UDENN FLCN/SMCR8-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004339</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000120">
        <property type="protein sequence ID" value="KAL1892930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037521">
        <property type="entry name" value="FLCN/SMCR8_DENN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021713">
        <property type="entry name" value="Folliculin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037520">
        <property type="entry name" value="Folliculin/SMCR8_longin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31441:SF2">
        <property type="entry name" value="FOLLICULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31441">
        <property type="entry name" value="FOLLICULIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11704">
        <property type="entry name" value="Folliculin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51834">
        <property type="entry name" value="DENN_FLCN_SMCR8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDENN FLCN/SMCR8-type" evidence="2">
        <location>
            <begin position="211"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="178"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="375"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="455" mass="49139" checksum="C9223F7BA79AD355" modified="2025-10-08" version="1">MLTPNIQLCLAHYCDTHGPTPLIVTEGAKVSCSTCYEGNTPLLMTGDVAPVDSPVLEQSLRRLSTTSHKPWSSQSSDEHHTRDTLIRSSTTTPSSRGSISPTETTPPDSPRRNEPQRRDSGFRKTYDENVTRRAGPCDNCALSVPPNIHQAAGNDDGRAPVLRSTLPYSKMPSGWQNSPPSSTESAASDSEADEALSSSTRQRTSTSRASMSSSRSPVGGHVHYMKYISTKEPLQPSSFSIVREACIRTLSFETLPRGPVSRLGSIPGFVTTHSAGYAASGGPIFFGDPVAGYTTAYIFRISDVHARGHKRIYAFMAISTHGERQVMQKFEYLARRFRQMAASIQQMAENEAEKATDPSPSPVLAPGPFVPPTLTSQFDTSSSTGSSTVAERDRGGSSFLSSGGGGLTRRMGAGGPGVSLKARGLAELVGQPDFFYQMHSSFAKLLYEMEHNKYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXJ3</accession>
    <name>A0ABR3YXJ3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Eukaryotic translation initiation factor 4E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TIF45</name>
        <name evidence="8" type="ORF">Cpir12675_004256</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the eukaryotic initiation factor 4E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000116">
        <property type="protein sequence ID" value="KAL1893110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.760.10">
        <property type="entry name" value="RNA Cap, Translation Initiation Factor Eif4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023398">
        <property type="entry name" value="TIF_eIF4e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001040">
        <property type="entry name" value="TIF_eIF_4E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019770">
        <property type="entry name" value="TIF_eIF_4E_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960:SF8">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01652">
        <property type="entry name" value="IF4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55418">
        <property type="entry name" value="eIF4e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00813">
        <property type="entry name" value="IF4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0810">Translation regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="257" mass="28885" checksum="868F9687989AA799" modified="2025-10-08" version="1">MASDMDKQVDLTTIPISPTDGLHEEKAPASTTAAMDNTKDITVFHDKDNFNVKHPLQNKWTLWFTKPPSGKGEHWNDLLKEVVTFDSVEEFWGIYNNIAPVSELAHKSDYHLFKTGVRPEWEDLRNKHGGKWSYQYKEKRNIDIDTLWMHVMMAVIGETLEDEDDGEIQGVVVNVRKGFYRISVWTGSIGRPIPGRGNGDVSGGKGRSDAKSEAILKNIGSRFKQVLKLNPSESVEFSGHIDAAQVGSTRVRSKFVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXK9</accession>
    <name>A0ABR3YXK9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Alpha-aminoadipate reductase</fullName>
            <ecNumber evidence="6">1.2.1.31</ecNumber>
            <ecNumber evidence="5">1.2.1.95</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">L-aminoadipate-semialdehyde dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="primary">LYS2</name>
        <name evidence="20" type="ORF">Cpir12675_004269</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the activation of alpha-aminoadipate by ATP-dependent adenylation and the reduction of activated alpha-aminoadipate by NADPH. The activated alpha-aminoadipate is bound to the phosphopantheinyl group of the enzyme itself before it is reduced to (S)-2-amino-6-oxohexanoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>(S)-2-amino-6-oxohexanoate + AMP + diphosphate + NADP(+) = L-2-aminoadipate + ATP + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46936"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58321"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58672"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="1.2.1.95"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>(S)-2-amino-6-oxohexanoate + NAD(+) + H2O = L-2-aminoadipate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:12308"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58321"/>
            <dbReference type="ChEBI" id="CHEBI:58672"/>
            <dbReference type="EC" id="1.2.1.31"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>(S)-2-amino-6-oxohexanoate + NADP(+) + H2O = L-2-aminoadipate + NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:12304"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58321"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58672"/>
            <dbReference type="EC" id="1.2.1.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-lysine from L-alpha-aminoadipate (fungal route): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.31" evidence="6"/>
    <dbReference type="EC" id="1.2.1.95" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000117">
        <property type="protein sequence ID" value="KAL1893078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05235">
        <property type="entry name" value="SDR_e1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014397">
        <property type="entry name" value="Lys2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010080">
        <property type="entry name" value="Thioester_reductase-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03443">
        <property type="entry name" value="alpha_am_amid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01746">
        <property type="entry name" value="Thioester-redct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44845">
        <property type="entry name" value="CARRIER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44845:SF1">
        <property type="entry name" value="L-2-AMINOADIPATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001617">
        <property type="entry name" value="Alpha-AR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0436">Ligase</keyword>
    <keyword evidence="13" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0521">NADP</keyword>
    <keyword evidence="12 20" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="19">
        <location>
            <begin position="635"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00031335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAL1893078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1177" mass="128841" checksum="02FD7E7BE7D29B37" modified="2025-10-08" version="1">MASPIPDPTIDLHWDDFKGAIHDIFESNALKHPERPCVTETKTATTPERTFTYKQINEAANVLAHYFVANGSQVEDVVMVYAHRCVDLVVAYMGALRAGLTVTVLDPLYPADRQIIYLEVAQPKFLVQIARATEDAGQLSEKVREYIDKSLSLKAEVPGLALLNGGSIAGGMVDGSDCLDAFQASKSKNPGVQVGPDNVPTLSFTSGTEGRPKGVRSRHFNLTYYFPWMAQRFGLNETSKFTMLSGIAHDPIQRDIFTPLFLGAQLLVPSRDDIAHELLAEWMKTYGATVTHLTPAMGQILVGGATSQFPMLKNAFFVGDILIKRDCRRLQELAENVRIINMYGTTETSRAVSYYEVPSRAQQPGFLDTLGDIIPAGSGMVDVQLIVVDRDNHSRMCGIGEQGELFVRAGGLSECYLGDDEKIKELNKTKFLNNWFVEPGRWEKEYTAKIASGNYNESWRPLFKGPRDRLYRTGDLARYMPDGNAEVTGRIDNQVKIRGFRIELGEIDTHLSRHPLIRENVTLVRRNKDEEATLVSYIVPEMKRWHGWLQDKGLPNDPTTDESMMTMLTKFRPLSDDCRELLKTKVPSYAIPSVFVPLARMPLNPNGKIDKPALPFPEASELRAATGMSRTVDQSQMPEIQQKVAQIWGELLEAVNAESLGPSSNFFEVGGHSILAQQMRLKVKKTWNGIDLPMSVIFQHQTVAAFAAEISRALDPTGLTLGTTDSVPTLDEAYSIDARELAEKLPASFQTANLDLSTTKTVLLTGATGFLGSYLLKDLMERNMKVFAHVRAKDAASGLARVESTAKAYGIWNDAWKEQISIVTGDLAKPSIGISEGEWEKLANEVDIIVHNGAMVNWMQPYSSMRPANVLSTLALIELAAVGRPKMFGFVSSTSALDSDYFVKLSKESVAAGGTGVLESDDMEGSSKGLGTGYGQSKWTSEYILRAAGKRGLAGSIIRSGYVTGDPISGATITDDFLVRMLKGCLQLQSRPYIPNTVNQVPVTHVARLVTASTLHPAVSPMAVTQVTAHPRLRFDQYLGSLETYGYEVPEIPYDEWRTKMEDYVASSTGGAKEEHALLPLFHFVTGDLPGNTIAPELDDRNAAASLKADAAITGQDLSAGGAVTEEIMGTYLAYLIATGFLPAPTKAGAKKLPVCELSEQQRVSLAAIGGRGGGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXW9</accession>
    <name>A0ABR3YXW9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_004476</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000127">
        <property type="protein sequence ID" value="KAL1892588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF10">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="18"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="90"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="628"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="635"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1892588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="721" mass="79215" checksum="818499EC210057CC" modified="2025-10-08" version="1">MAPSSNRRAESPPRRLRACLPCTKAKAKCNFKSENQSRHLCDRCHHLGIECTAKTTKGIRKPRQLKPLASRVASLEQIIDNLTTRLASAEDSSHDYAPLNSAGPTRHPSVNTPESVSGSSDGGNDGRITPGAASASIISTTTTRPPSSKGSIASNPSSGLSAGNSVEAGGSNSNIGTSVMGSVICTSNDNTSPPFRLNWDQVNLAVMEFKARYTPAFPFVVVDEKPIEQLLADSPFLVRAIIFITVPFTPAMLKAIRKDLMTYLAMRSLVEASVSLDVLQGMLILIAWGPIRLAPTQIHQMMNLSVAHARSLGIVMPRVSQNNWHTTSKGPEDPRQASIAQNTTTLTMAQQRAYLGTFYLSEISSCRGGYQPLLNGSPLDVHAATRLLTSDTQSDFMVEKIVSIAEVTNKTAAIFGIPYARDRKPTYAAVVECRSQPLRAQLDKIAQGVAPDHPNFSHFRMHYTYALVRLYEPATFITDAVQRTTPSLYHLQALGDCLVALKDFFAAFVSIEPHAATGGFQTYATLATLEQVSLAACVAVRILLLELEGWDLALARLQLDFSRIMESLLQLLRRADMARLHLEARFAGVRREDGSVPAEDFGSLERYVKNLHLLRVWYERRSAATEVPAVPPVPQAQATQRQQRQQTYQNQQHHQMQHPTQAHVQASQQVQQAQAQAQSQQQQEQQQHSTSENALGGFELDLSGDWPVIMMGEWALDTSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXZ6</accession>
    <name>A0ABR3YXZ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_004403</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000123">
        <property type="protein sequence ID" value="KAL1892792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1892792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="261" mass="28947" checksum="16BD4E070C25B1EE" modified="2025-10-08" version="1">MTDWMGSIDDSVLLSKLSIPGTRHSTTDNDALDSMQTQNVVHGVCKTGYYVADVVATIYNFLSEHSRETVILRIKKGSTLDSLEEFTTLIHRYLRPDAPIDYNPASHVHYKGLAVRGKMLVLQDFESQPPGLYGLPWNSPLDSSEHLPPLRYTLVNRIKPSATESHIVSLSKRILNELHVAETFNGGNSKPDKYYTGTSIDAKINNWLGASLSKAKKNDHSEYLVEGEIADVGILAMDHPGKNLVEQIVKLNNVYRGSPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYE2</accession>
    <name>A0ABR3YYE2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Release factor glutamine methyltransferase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_004148</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000111">
        <property type="protein sequence ID" value="KAL1893410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004556">
        <property type="entry name" value="HemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050320">
        <property type="entry name" value="N5-glutamine_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040758">
        <property type="entry name" value="PrmC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00536">
        <property type="entry name" value="hemK_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18895">
        <property type="entry name" value="HEMK METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18895:SF74">
        <property type="entry name" value="MTRF1L RELEASE FACTOR GLUTAMINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17827">
        <property type="entry name" value="PrmC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Release factor glutamine methyltransferase N-terminal" evidence="4">
        <location>
            <begin position="29"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="355" mass="40136" checksum="8FF3FABE2F98E7A3" modified="2025-10-08" version="1">MPRIPPWLLTQAASIDPNLARLLPVCRGLASARNELRWLTEHVSGDVPPSARLTARQRAKLKQLCTRRRTGEPLQYILGTQPFGKLDIRCRAGVLVPRSETEAYTLHLADILRHRQGEEGMRIIDFCTGTGCIPLLLYSKLQNCRGQPVTEVRGVDISPEAVDLSHENLRYSISTGKIQPPSAQCRMSFVQADVFDDTAIAEVSRGGPWDVLVSNPPYVSREAWTEGNRGLSMSARKFEPKLALVPQDEVPRSEHCQHEDAFYERLLTVARALRSRVILLELGDAEQARRVLTLIHRSGLLRDASRVEVWRDWPDMQRQEDEDDMLNAQKSNGENWRVKVRGSGNIRCIFMITSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYG4</accession>
    <name>A0ABR3YYG4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinetochore protein mis13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000119">
        <property type="protein sequence ID" value="KAL1892957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013218">
        <property type="entry name" value="Dsn1/Mis13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14778">
        <property type="entry name" value="KINETOCHORE-ASSOCIATED PROTEIN DSN1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14778:SF2">
        <property type="entry name" value="KINETOCHORE-ASSOCIATED PROTEIN DSN1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08202">
        <property type="entry name" value="MIS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="496" mass="55626" checksum="41CF19B0F4356FD9" modified="2025-10-08" version="1">MSSQPQRRYSKRLAATSYDEQDGDFVFTRASKRTKTNNEETPIAPPKKTSRGRPPKEKPTTIPEYEHEALAHSSVQPAPTRKTSRRKPAIFDGQEQDEFAQLILPKRTRRSTRVSTAVPDEQPQEHQRQDDVPQPPAPRQQKASRKKQNGTSQARQPRLPAQDPVAEERTTLVLTTPTLNGEESIHDISPVVPAGAKIALPLSDTPIINRNKEMRKKGGGRRRSSLGMRGRRASSLTSMGHSALPHKEVKEAEFYKHIEAEGLPEPHRMKQLLTWCGERALSAKPPLGSSHSNAILGARAIQDQLLKDFQSKSEFSDWFSREEVPLPPVVLKPNPRNIEHEEKIAILEAKVSRLRELKKTWQALRKSPQEITSPMNEPSTQDSQDDAELLEASDKRILDAVRSPGAVSALAIRQKTLDRLRNIQSTLEIKVDLLADGAHKLEQRVTTAGREADRVLSLSSNRLKDREKREKALTGTKDMPVMEVLRSLGQILPQNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYI2</accession>
    <name>A0ABR3YYI2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">NADH-ubiquinone oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">NdufA8</name>
        <name evidence="12" type="ORF">Cpir12675_004278</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the complex I NDUFA8 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000117">
        <property type="protein sequence ID" value="KAL1893087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010625">
        <property type="entry name" value="CHCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016680">
        <property type="entry name" value="NDUFA8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13344:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13344">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06747">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017016">
        <property type="entry name" value="NDUA8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="CHCH" evidence="11">
        <location>
            <begin position="91"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR017016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1893087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="173" mass="19601" checksum="8737028E4A4B27B6" modified="2025-10-08" version="1">MSTRTPKFDQSFLYDLAPMPDHIPKVEELGASSAPLLSAAFFIGARCRPYNDDFMQCKSEANGRGEFDCMKEGRRVTRCASSVIKDINTHCLAEFRKHWQCLDNGNHQLWQCRGEEWKLNKCVYENLKLEKQIPDQPKISTPVHLRQSQIFADHPVSPGSKPFIAAASSKESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZJ6</accession>
    <name>A0ABR3YZJ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GrpE protein homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">mge1</name>
        <name evidence="6" type="ORF">Cpir12675_004088</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the GrpE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000108">
        <property type="protein sequence ID" value="KAL1893480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00446">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.22.10">
        <property type="entry name" value="Head domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01151">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000740">
        <property type="entry name" value="GrpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013805">
        <property type="entry name" value="GrpE_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009012">
        <property type="entry name" value="GrpE_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237">
        <property type="entry name" value="GRPE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237:SF23">
        <property type="entry name" value="GRPE PROTEIN HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01025">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00773">
        <property type="entry name" value="GRPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58014">
        <property type="entry name" value="Coiled-coil domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51064">
        <property type="entry name" value="Head domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01071">
        <property type="entry name" value="GRPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1893480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="249" mass="27655" checksum="E95285D593DDDE63" modified="2025-10-08" version="1">MLKQSIIRSSRVALRSQSLIRVPFVSSISATRSPATTVSQSAFRWYSSEAPPKESEAAPKEGEAAPKEADDELSILKKKLETKEKEALEFKDRYLRSVADFRNLQDRMTRDMKSARDFAIQKFAKDLTDSVDNLDRALIMVPEAKRIAPADDATATLTAADAAQYAQDLANLYEGLKMTETIFVSTLAKHGLERFDPEGSKFNPNEHDATFMAPQADKEDGTVFHVQQKGFKLNGRVLRAAKVGVVKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0A7</accession>
    <name>A0ABR3Z0A7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein bL27m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_003854</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000098">
        <property type="protein sequence ID" value="KAL1894070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001684">
        <property type="entry name" value="Ribosomal_bL27"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL27M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893">
        <property type="entry name" value="RIBOSOMAL PROTEIN L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01016">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00063">
        <property type="entry name" value="RIBOSOMALL27"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110324">
        <property type="entry name" value="Ribosomal L27 protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="268"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="62"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="276"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1894070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="298" mass="33823" checksum="73CAB02B0B1CD63E" modified="2025-10-08" version="1">MSLSQLQRPFAAVVSGFARPLLSSSLLLARERPTISFQCKINAMNLTAEGRRNASVKAQGAYKHRPKRTHPKKMGAKRTGDQYVVPGNIIYKQYGTLWWPGENTIMGRDHTIHAAVSGYVKYYRDPVRHPDRKYIGVVFNKEDTLPYPIHAERKRRLGMAPVAKEVIEAKPEMSSSGIPNTVIRAHPHKPEQSQVLNLQDDYTYRESSWAIGRLVKTTDLQLKRFKSRRAFFRHRRWSRERYLKGMKKAAERQAEDGAEDEWVAAARAKTQTAGKSKGKKAKKVKGGAKGSAKIRAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1L2</accession>
    <name>A0ABR3Z1L2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_003822</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000097">
        <property type="protein sequence ID" value="KAL1894087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16473">
        <property type="entry name" value="RING-H2_RNF103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051826">
        <property type="entry name" value="E3_ubiquitin-ligase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765:SF434">
        <property type="entry name" value="GB|AAD18119.1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765">
        <property type="entry name" value="RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="54"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="268"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="145"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="182"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="252"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1894087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="462" mass="50834" checksum="B50A5D02718F08B2" modified="2025-10-08" version="1">MPLVARIVHEATKVVASSHDHYLLIRQDTTSTSASPAATSDPADGDGKGRTNSLLFFVALGFGVVFTNLWIMVGVKYCFRYNSRNHQLRVAAEGGEMVLLEQPTRPRRRRVKKLMTMEEVNHKFPMIKYKSWVLQKATSIRTAVPAAAANDSDPKELSPISNSSDELVSDPMNLASDVTPVVSASNVQTSNKSPGSITERDDNEETQHVEKVASMLSVPPPVARRDGENAPPSSTNQSDTEADEDSEDDHSNTTPPNLNETNPDADTCAICIDTLEDDDDVRGLTCGHAFHAACVDPWLTVRRACCPLCKADYYVPKPRPEPPANPEATEPLQVSRVDSARGAWLNFRGVRQIPPNMTPEQAQAYARREQQRARRVRRRQAELVAAQRDEQELRALQRRQHRHQEAGGVVGSLRNAFSGFRLGRIRNTQSNSNATSNVLSTSASDFAQPGTGNTTAPPHQQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1Y2</accession>
    <name>A0ABR3Z1Y2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mitotic exit network component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">MOB1</name>
        <name evidence="2" type="ORF">Cpir12675_003733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000093">
        <property type="protein sequence ID" value="KAL1894305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.30">
        <property type="entry name" value="MOB kinase activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005301">
        <property type="entry name" value="MOB_kinase_act_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036703">
        <property type="entry name" value="MOB_kinase_act_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22599">
        <property type="entry name" value="MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03637">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01388">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101152">
        <property type="entry name" value="Mob1/phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="218" mass="25245" checksum="73E3DD08BDC63D81" modified="2025-10-08" version="1">MASFLTTVNQRTRQQFRPRAGKGGGTSHQLRQYAEATLGGGSLRKIVKLPEGEDENEWLAVNMVDFYNQINLLYGAITEFCSPQSCPEMKATDEFEYLWQDNENYKRPTKMSAPAYIEQMMGWVQGNIDNEQILPSRIGVPFPKSFPSLVRQIFKRMYRVYAHIYCHHYPVIRELGLEPHLNTSFKQYVLFIDEHHLASGRDYWGPLGDLVESMLRSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z245</accession>
    <name>A0ABR3Z245_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein SLG1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">wsc1</name>
        <name evidence="5" type="ORF">Cpir12675_003838</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000097">
        <property type="protein sequence ID" value="KAL1894103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047129255" evidence="3">
        <location>
            <begin position="18"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="4">
        <location>
            <begin position="43"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="159"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1894103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="290" mass="29666" checksum="FD10324FBC9F8407" modified="2025-10-08" version="1">MRLSYIVAAGLLQFASAQSSAGGSSGQTTKGYQAPSQIPTPGSQTTVGCFSSSGNLTDPGGYADTSVSSGFCGVSLCVEKGFTVFAIRGPKCYCGNTYPPEDDIVEDSRCNYPCPAYPAEACGGISSGGAWSVFNSGIEVDVEYDTSSSSTTSAAATSTAAATPAGGNAATSATAPATTTSSDGKGNDNDKKSSNVGPIVGGLVGGIFGLAAVAGGVFLYMRRRRNREIEEEHRRNAAVNAFINGKSSPGGSMSISDSRLDPVMAQRRMSDGSIADNEDYSRRILRVTNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2T4</accession>
    <name>A0ABR3Z2T4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ATP-dependent Clp protease proteolytic subunit</fullName>
            <ecNumber evidence="7">3.4.21.92</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_003632</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase S14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.92" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000089">
        <property type="protein sequence ID" value="KAL1894506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033135">
        <property type="entry name" value="ClpP_His_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018215">
        <property type="entry name" value="ClpP_Ser_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001368">
        <property type="entry name" value="PRK00277.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381:SF11">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00382">
        <property type="entry name" value="CLP_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00381">
        <property type="entry name" value="CLP_PROTEASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0720">Serine protease</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="254"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="254"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1894506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="276" mass="29500" checksum="581C0943CD6DFF48" modified="2025-10-08" version="1">MACTSKLVRVTRHAFRAGVGASASPSTTARGFSTTAHRALTGTGRAGLHMPPTSNIPMPYITEVTTGGWRTYDIFSRLLQERIICLNGSIDDTTSASIVSQLLWLESDSPDKTITMYINSPGGMVSAGLAIYDTMSYISSPVSTVCVGAASSMASLLLVGGARGKRYALPHSAIMVHQPLGGTQGQTSDILIYANQIQRIRDQVNEIYRTHVNAALPQDKHLSKETVEALMERDNYMTAQEALANGVIDEVLVRRTEDSKGDNTKGPAPASAPAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2X6</accession>
    <name>A0ABR3Z2X6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003442</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000081">
        <property type="protein sequence ID" value="KAL1894983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047364980" evidence="2">
        <location>
            <begin position="18"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="205" mass="20324" checksum="85FCB3E211C9BF62" modified="2025-10-08" version="1">MQFNLATLAMMAAGASASLQGGEVYGAPEVTTTSYTTVGTTTLHYGDIDTTVTQTSTMFKTITLTSCAPDVTDCPGHTSTSTTSTGTSTTTSFTTTTTSTSTGASSYFPLVNSTAVYHPTVASTGFHTVPLVTASSYLPIKTGSTPTAGVTYSSPSEAPAPPAEAPITPAAPASTTPAIITAGASGFAVKGGILAGSLALAMLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z350</accession>
    <name>A0ABR3Z350_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">SMP-LTD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_003657</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000090">
        <property type="protein sequence ID" value="KAL1894480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21675">
        <property type="entry name" value="SMP_TEX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13466:SF19">
        <property type="entry name" value="NUCLEUS-VACUOLE JUNCTION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13466">
        <property type="entry name" value="TEX2 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15413">
        <property type="entry name" value="PH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="7" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SMP-LTD" evidence="10">
        <location>
            <begin position="296"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="551"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="609"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="727"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="786"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="984"/>
            <end position="1172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="626"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="652"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="675"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="742"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="786"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="797"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="840"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="863"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="880"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="984"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1015"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1091"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1135"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1158"/>
            <end position="1172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1894480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1172" mass="126715" checksum="0D596487A4257303" modified="2025-10-08" version="1">MPWASFLFAYVLGGLTLIPLVLLAGLLHAHLTFPYYKTGRPDGGNSDVVTDDDLIQPGDDVSLLQTEKRAHEAAAAATSGSASSARRTNEDDMASGYFAVCREYTPMGINAKPIERTTPVGSTTVAAPSQSVYQTMYKSLFERKTTLKESDSGTSSSWSRKTGNIFFIVLRHGHLMLFDDEGQLEVRHVISLAHHEISIYSGGGVTPEGELYIKKNAICLSRRKDSADLVAADAQPTKPFYLFSENCSAKEDFYFSLLRNQEHTFRDASKDMPPPPQQFEVKDVISLVQKLHSSEDHLQTRWLNAFLGRIFLGIYKTEDIQDYIRGLLMKKISRVKVPSFLTNIAIRKIDTGQGPPYIINPKLREMTVDGEFLAETDIKYTGNFRMEVAATARLDLGARFKAREVDLMLSVTVKRIEGHMLLRVKPPPSNRLWFSFAQLPKMEMVVEPIVSSRQITYTVILRQIENRIKEVVAESLVQPFWDDVPFFRTEDKKWRGGVFEGNEFVASGGTETQETDIKTDAKVDVKADIEDDTPLPDIALKTEVIPTMEKSHSFANSENTTIHKRKTWTEPGADGNGLETAASSSVDFKQTASSLSISPQASNENLAAALKTPPKPSTPHKTLSTQTPSSYKSPTNRTQHLESQQNTPSRPSQAVDFSQSSSSQSPAQPKKSLSTLAKNDNSEALSDTEVDQASPTRFNLSANSALATKAAVSSKMMPPVFPEEIELETEPTPYGGRRGTVSSMDSDGNSSTSGLKLGRANTVNSVKSQAGSFLSKTAAFLANSSGSSIGSANGNNVRISRSNSAHDNYSRNNNSSVSLESTPAGASNDGNDNENSGVDSNNSNSAAPVSAVPFRASRPDSRYSYNGKTGSISELPEASLPSTSFLDRENSPTPNITKRNTLAAMSSAAAYARNWGINALARRKESNSSATATAAFDSPAIDLSQPMGRGQPLPPIGTPLPPPEKGNRLTSLPVMKRHSLATPLSTPAISQSTPSAGTITAQSSLPASTTINTQSPISRIPSPLPLRRSPSTASVSSISVAASLSRASSRQSLRQASPIQRKAIEQGSFLPTGDPSLLVVAAPDDFSEPGTPREDEASRDDEWSGTGTGGGFSPVVRSMSRRSYRRSSYGVFQPPGSASSSSSALGLKRSPSRLSNGQRDDDYAASWLDDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3J5</accession>
    <name>A0ABR3Z3J5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_003535</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000086">
        <property type="protein sequence ID" value="KAL1894645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01767">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46340">
        <property type="entry name" value="UBX DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46340:SF1">
        <property type="entry name" value="UBX DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22562">
        <property type="entry name" value="UBA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="44"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="96"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="140"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="219"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1894645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="313" mass="34370" checksum="0D32F9E0BFE79A9C" modified="2025-10-08" version="1">MVQSDLDVLLDMGFEKERAEIAAKKSGGLQGALQWLEDNQDKSLEDIKKEAATQTESTKAESQSDDTNDSANSLVCNECGKLFKNADLATFHATKSGHTDFSESTEAIKPLTEENKQAKLQELREKLNAKRAAQSVNDQETQRQNEKIRMKATKETQDAKEKLQREEQLRQVAKKRQEKEADKQALARARAQIEANKEARRQKEAAAKAAREGRVGEESVTAPVPTPAASSSAPKPAHSEARLRLQTPSGNIMKTLPAETTLAELAQVVASENGFQVTSFSTTFPRKTFEGAVDFSKTLKEVGFVPNAAVVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3P9</accession>
    <name>A0ABR3Z3P9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003512</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000084">
        <property type="protein sequence ID" value="KAL1894817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045169220" evidence="2">
        <location>
            <begin position="21"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="292" mass="32876" checksum="DBEF82F66294CE77" modified="2025-10-08" version="1">MRFFSVSMPLALSILGLAQASSLKDYGYEVTSAGTVDTVVSFDQDGQLQLIDVFGFNTLTKMVTIYVDNNDLEPESEKKLGLGQIYVSLLEERDQKPEDINWIITDIGGETEITKLISDIREGRNVDPTSEIIIHPDHKEWKSILDTKYYKKAAALNTKPLEAIIIKTAERSIYEGSAEVDSFYFHFPTKKTENTEGEVPASVDDNQKDEAAGWFDELNEDLKEDLEDEWEGEKDEGAIMRELFAEQEEQNIASLETVYDRLSELIPAFEESEEALTKSDEAPAENEEAPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z410</accession>
    <name>A0ABR3Z410_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Multifunctional tryptophan biosynthesis protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="16">Anthranilate synthase component 2</fullName>
                <shortName evidence="16">AS</shortName>
                <ecNumber evidence="16">4.1.3.27</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="16">Anthranilate synthase, glutamine amidotransferase component</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="16">Indole-3-glycerol phosphate synthase</fullName>
                <shortName evidence="16">IGPS</shortName>
                <ecNumber evidence="16">4.1.1.48</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="16">N-(5'-phosphoribosyl)anthranilate isomerase</fullName>
                <shortName evidence="16">PRAI</shortName>
                <ecNumber evidence="16">5.3.1.24</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="21" type="primary">TRP3_1</name>
        <name evidence="21" type="ORF">Cpir12675_003433</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 16">Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 16">
            <text>1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:23476"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="EC" id="4.1.1.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:21540"/>
            <dbReference type="ChEBI" id="CHEBI:18277"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="EC" id="5.3.1.24"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 16">
            <text>chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21732"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="4.1.3.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6 16">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 1/5.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 16">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 16">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.27" evidence="16"/>
    <dbReference type="EC" id="4.1.1.48" evidence="16"/>
    <dbReference type="EC" id="5.3.1.24" evidence="16"/>
    <dbReference type="EMBL" id="JAWDJO010000081">
        <property type="protein sequence ID" value="KAL1894974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00331">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00405">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00135">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050472">
        <property type="entry name" value="Anth_synth/Amidotransfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016302">
        <property type="entry name" value="Anthranilate_synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013798">
        <property type="entry name" value="Indole-3-glycerol_P_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001468">
        <property type="entry name" value="Indole-3-GlycerolPSynthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001240">
        <property type="entry name" value="PRAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00566">
        <property type="entry name" value="trpG_papA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43418:SF4">
        <property type="entry name" value="MULTIFUNCTIONAL TRYPTOPHAN BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43418">
        <property type="entry name" value="MULTIFUNCTIONAL TRYPTOPHAN BIOSYNTHESIS PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00218">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00697">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001382">
        <property type="entry name" value="TrpG-trpC-trpF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00097">
        <property type="entry name" value="ANTSNTHASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00096">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00614">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 16" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11 16" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8 16" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="10" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="12 16" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="14" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 16" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="18">
        <location>
            <begin position="27"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Indole-3-glycerol phosphate synthase" evidence="19">
        <location>
            <begin position="256"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="N-(5'phosphoribosyl) anthranilate isomerase (PRAI)" evidence="20">
        <location>
            <begin position="578"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="231"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR001382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAL1894974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="764" mass="81972" checksum="BDEE2CC6F13EFC72" modified="2025-10-08" version="1">MASLDIIDHSPQHPEPSPPVATASNLVMIDNYDSFTWNIYQYLVLEGATVTVLRNDQVTLDELIAKNPTQLIISPGPGHPKTDSGISRDALKHFAGKIPIFGVCMGQQCIIDVYGGEVSSAGEWLHGKTSPLSHDSKGVYQTMAQSLPVTRYHSLAGTHATLPECLEVTSWIARPDGSQGVIQGVRHKTSTVEGVQFHPESILTAQGRTMIRNFLKMQGGTWEENARLQKEASSSSTLPSSKNDTVPHVKPSGNILARIYAARKIAVDDQKLIPGLRPSDLQSAYDLNAAPPVVPLLRRLRQSPFEISLMAEVKRASPSKGIFDLDISAPEQAHKYALAGASVISVLTEPEWFKGSIDDVRAVRQVLSSMPNRPAILRKEFIFDEYQILEARLAGADTVLLIVKMLEEALLKKLYDYSLSLGMEPLVEVQNADEMEIAVRLGAKAIGVNNRNLESFEVDIGTAGRLRSMIGKETILCALSGITSHDDVKQCKADGIDAILVGEALMRAPDASRFIEKLCAGTETVKPVAAPSPLLTKICGTRSVEAALEAVNSGADFIGICLVPGAKRCITEETALAISHAVHEKAASTATTASPSSRAQDFFSAFETRLPASKPRLVGIFQNQPLEEVISLASKFGLDMVQLHGEEPLEWASQIPVPVIRCFKPGQVGIGSRGLHTISLLDSGSGSGKLLDAVGVKSILSKDPNLRVMLAGGLNPDNVAEAVKAVGEYAGRVIGVDVSSGVEEDGNQSLAKISAFVKAAKSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4H6</accession>
    <name>A0ABR3Z4H6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Factor arrest protein 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">FAR11</name>
        <name evidence="4" type="ORF">Cpir12675_003220</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000072">
        <property type="protein sequence ID" value="KAL1895531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040185">
        <property type="entry name" value="Far11/STRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021819">
        <property type="entry name" value="Far11/STRP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012486">
        <property type="entry name" value="Far11/STRP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13239:SF4">
        <property type="entry name" value="AT25231P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13239">
        <property type="entry name" value="PROTEIN REQUIRED FOR HYPHAL ANASTOMOSIS HAM-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11882">
        <property type="entry name" value="DUF3402"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07923">
        <property type="entry name" value="N1221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01293">
        <property type="entry name" value="DUF3402"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01292">
        <property type="entry name" value="N1221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Far11/STRP N-terminal" evidence="2">
        <location>
            <begin position="118"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="Far11/STRP C-terminal" evidence="3">
        <location>
            <begin position="544"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="808"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="827"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="839"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="866"/>
            <end position="878"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1895531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1070" mass="118876" checksum="CC81905C476B6947" modified="2025-10-08" version="1">MSAIWQYSSGQNNERSSDDVTGVAPEMITGPPPPPPNSQQQQRPDFQTRISRNRPQGQRPPNPPPNTTVSPWPPAPTPGRKSSIDGRMGPIPTEGPQDSLSLGQLKRIVAGFQRPEKMSCYDYTYNDFGSFAEEISEWFVDGAWSWNSLDNARRSYYWQWEDATQYISSLIAENDPAVHDIDIAHLATWEDATTRLKDGVVRGALDVIKDGDISQRSPAIGSLTYIALGRWEDTAHKPAKSGSITPATEMQLEEMVAGISIMTKLGGLPIIWDTILKMLHSVWDVANNVATMSEGELSDLSSDMMHLMTILYVAMQVSLSYPADVAAPIATQIIELKPPIVETLLIETTKRRFDDGDHLPQTQMLLLLWKSILVVFGGSKELLETKKAARESSLEDKAQNLILASPLDYHVFRDEIASKYPAYIPPHSNLPHDNIGKSLLSALSNQPQRNAMNGGIIPPAPGTQVEGSTSILNQPVHIATPAPSPPPSPAAGGKAIKKQNYQTNQDFPFLYPPLDATSNSAGGKGFAGEQWESVGRRWEGSELPTSIIEAGNLFSDRVRMSRAMRQMWEEREAFLKENKGWDPVLKLSSEPDATANVDDNDDIESLDLSELTLEEKQELTRVRKLMREEEDGGRVTRDELGLPEVPIDLGPNPEMMMPETKQRLIAIDSFYRQGLPYFQSLVIVLLKTIMANVSSLPVPVPQSAHPVGLKMANSVQETHRTPEEMDGAKGHEVTAKAVTGILILLLKWFKVSHVLKFEYLTQMLLDSNYLPLVLKFFIHQEIANIVESKTDRPENSFFHVCNVQAKAGASESESDSESDSEARDNPETSLEDSSQNPENEAEAGSSEDDAIPPPIKRRRSPPLAPLNTSAPLNPNNSRPEVDELGFPVNAEVPLAPVTDFSRRNFFSLINYLRVLQKICKGKAHRNLLMVTYKSSTILRKSLRVPQDDLRLYTLKLIKSQVSFCGRKWRQSHMRVITAIYLHCRPEFRDEWLSGSDVDGDIESALPLEQALRSLTHWSNVRRYPDKVAAASGVRAALKAERDFFAREVEKLGAIDLSGSLEDGQGGYNGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4T4</accession>
    <name>A0ABR3Z4T4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UBC core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_003625</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000089">
        <property type="protein sequence ID" value="KAL1894499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1894499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="686" mass="77335" checksum="5CB0CF69AA5A93F7" modified="2025-10-08" version="1">MVLGLNWEEFKVLRYLPVQFSLTIRACLTTACRTCTQSSSTSKLSCICGQECAVPDGREAQHGEGNNKAPPPPTNACVTGLSMLLWGLCMCDYPSEFMHESDGPFVSKNKAVQNLLHLDKIKQKFARFREAQRNVQRNVQKRLSRFSEPADGDVPAKASATTKQKLRPEPEVSNLNIAQRLEVMVKIMQFFKRSEYHVMPLVSHMILRSNILHCVAAIIETIDPASSTVSLLQIAALDWAMALYCDEKLRDLVLLQYVTLNDKHRVKAIHDCNKPPILSSQDMLEYIPYLRKSIAGRIISKAKPVATYNGKSLSRAGELCKAQELPPTHQYHTDLGLLAKDMLEEFGDKLQHDLGLIGLKRILYMRKVTRSESWSSWIFQGNNQVNKVPDVDFIKGFYFPEGFKREFEATKEATQRLLKDITQTWPRQFIIRYNEEKPDLIRVLVAGRKCSDHEGGLFEFHFMVPKCYPLYPLKAMLGIPNGVIEKPFGADVCNEINMITYGQTGSIRDDIIKMAEGIFRPVEEMPDVTTGDTAAILNSLALRYQENSALYKCVVHGMNIWFDAPETGDLGGFRIAKTHPVWGEAVNMWFLLNSRQLAQKASMIHTRLLRPWKEYDSNAKLPSSLTPVRKGVINTQITARAAERLFRLSVVWEAYLKNTQTHTTGAKGEVDGVGVGSLFVGDAAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5I1</accession>
    <name>A0ABR3Z5I1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">[4Fe-4S] proteins maturation</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ISA2</name>
        <name evidence="3" type="ORF">Cpir12675_003277</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HesB/IscA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000075">
        <property type="protein sequence ID" value="KAL1895320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="ATAP_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43011">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43011:SF1">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core" evidence="2">
        <location>
            <begin position="101"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="235" mass="25686" checksum="8EEE84DEB4895980" modified="2025-10-08" version="1">MPHIACSASGPAFRLPILLARSTIASIPGLDFLYPAFSRRTFSTVPRSILNPSTVSYRAGSFRYLSRAIKSHAHRGFGTTTPQQKTLCIHNPTVDEDGKDMHMEITTRAAKRLTKIMKRDNKPGLALKVQVESGGCHGFQYTMSLVEIPDQGTKEWGETVGEDNTIFQYIADDAVNLDNALQGSPKIILDEPSLSLLKDSKVDFTSELIGSQFKIVDNPRATSSCGCGTSFDVAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5S2</accession>
    <name>A0ABR3Z5S2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003006</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000065">
        <property type="protein sequence ID" value="KAL1895966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42336:SF1">
        <property type="entry name" value="ALKYL HYDROPEROXIDE REDUCTASE SUBUNIT C_ THIOL SPECIFIC ANTIOXIDANT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42336">
        <property type="entry name" value="THIOREDOXIN DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="302" mass="32211" checksum="F981EC95F1D462E4" modified="2025-10-08" version="1">MFSSLATKIALKKSGLPAALPNLDPNPKPRRSKTALASSRENDDGGDGPAASWPAWMSIKALPLAVQPWFTPAPPPVPIAALPEIGHLAPQDRDHKLLLGDGRNVLVVFLRCVGCAFAQQTFLQLRDISQRAGRDLNCIAISHSSSAATAKWLSILGGARSVQVIIDEERLVYAAWGLGLASVWHMFNPTTQAEGWRQKDGWLGQKVASSITRPGLGGKGKSLFEAEEEEKVNTRNRDASGRTENTGLPADDEGGPSSAMGNKWQTAGAWAVNGRGVVIWGGQAKSADDTLNLYDGCRSLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z625</accession>
    <name>A0ABR3Z625_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">40S ribosomal protein S29</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS29</name>
        <name evidence="6" type="ORF">Cpir12675_003219</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uS14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000072">
        <property type="protein sequence ID" value="KAL1895530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.10">
        <property type="entry name" value="30s Ribosomal Protein S14, Chain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_uS14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018271">
        <property type="entry name" value="Ribosomal_uS14_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039744">
        <property type="entry name" value="RIbosomal_uS14_euk_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043140">
        <property type="entry name" value="Ribosomal_uS14_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004424">
        <property type="entry name" value="PRK05766.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12010">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12010:SF2">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00527">
        <property type="entry name" value="RIBOSOMAL_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1895530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="56" mass="6635" checksum="5881BFC5C94E865C" modified="2025-10-08" version="1">MSHESVWNSRPRTYGKGSRSCRVCKHRAGLIRKYGLDLCRQCFREKAKDIGFNKFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z665</accession>
    <name>A0ABR3Z665_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chromatin binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SWD1</name>
        <name evidence="8" type="ORF">Cpir12675_003159</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000070">
        <property type="protein sequence ID" value="KAL1895575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056432">
        <property type="entry name" value="Beta-prop_GEMI5_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037850">
        <property type="entry name" value="RBBP5/Swd1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44040">
        <property type="entry name" value="RETINOBLASTOMA-BINDING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44040:SF1">
        <property type="entry name" value="RETINOBLASTOMA-BINDING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23770">
        <property type="entry name" value="Beta-prop_RIG_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="28"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="Gem-associated protein 5 first beta-propeller" evidence="7">
        <location>
            <begin position="34"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="62"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="430"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="453"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF23770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="464" mass="52961" checksum="34A9D1C43FAF872D" modified="2025-10-08" version="1">MNLLLSDDYLPQDYPEHITNTIRSGHATCLRFNYKGDYLASGRVEGTVVVWDLDTMGTARKLRGHNKTISSLSWSRCGRYLLSACRGWKAILWDLHDGKRLREVRFRAPVYTAEIHPTNHLLFNVSLYEEQPFLVDVSNPVDKRDILPSIKKRDTTDLDPETIEKHAKEDAKQMTTAMIFTSNGDHIIAGTNKGRLNLVDTKTREIIYSEKVCSGAITTMKITGSGKDLLVNSQDRIIRTFKVPNLSSEHLDIDTIQLPLEHKFQDVVNKLSWNHVTFSATGEYVAASTYNNHELYIWERGHGSLVRMLEGPKEEQGTIEWHPHRAVLAACGLETGRIYIWSVTSPQKWSALAPDFAEVEENVEYIEREDEFDIWAQEEIHQRRLDAEDSDVDVLTKPPSKLYDDYDGQFRMPILFNLGESDSEEEFVAVSTGTMRRRSPGEGEAADDERPVVPKKKVGRPKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z670</accession>
    <name>A0ABR3Z670_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Palmitoyltransferase</fullName>
            <ecNumber evidence="10">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PFA3</name>
        <name evidence="13" type="ORF">Cpir12675_003059</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="10"/>
    <dbReference type="EMBL" id="JAWDJO010000067">
        <property type="protein sequence ID" value="KAL1895781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12246">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10 13" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="194"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="12">
        <location>
            <begin position="105"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="273"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="396"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="451"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="492"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="509"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="527"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="539"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="608"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="633"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1895781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="651" mass="71510" checksum="A58B6CF097BC8E42" modified="2025-10-08" version="1">MAPRRWARRLERTCCRFVTSIPLALVYGLTTWALWVILSIGSNPPPDSWIGSCSSIFGVFLYLMLNWSYTTAVFTDPGSTTRSNGDYSAIEAPPHSTSFTVKSNGEIRYCKKCQMRKPDRAHHCSSCRRCVLKMDHHCPWLATCIGLRNHKAFLLFLIYTTVFSIYACAVSSTWTYVEIMGDMDTLDSLVPVNYITLAVMAGIIGIVIGAFTSWHIALAARGQTTIECLEKTRYSSLRDQIYNYHSERRPGGRFSQPSYGQQIIDMHANAIPGVTRPEEGEDERASTPPVTGLDGQRPAYLSYSEMEQRQSQKRYQEYLDEEDSRKLPNVFDLGWKRNLRHLFGPVPLMWFFPICNTIGNGWSWDPNPNWINERERLRVERENQLRREVEAGWGSEDPSFMHSSGGLNISTPPSSSATRNYLSGPVNHHDNVAKGNGMTLGHANKSRRPMSKADRILGRDPDQYSDDNPNSISMKRLTPKGMAIGDDLLNSDLDDDGDEDDLLGEVSPKPQPVLKPQPANPRAAAPALPPQSPAPPSQPAIAPLSTQPSLPTPTESTITVSSTSPTATSSKAASPTLSTTAKKPLASGILGSRRWESSAASGLLRKTSPVSSTTGSASLARAGSVSPFHATLQGPQSGATSQAESSDDDID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6E7</accession>
    <name>A0ABR3Z6E7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GTPase activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">GYP7</name>
        <name evidence="3" type="ORF">Cpir12675_003070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000067">
        <property type="protein sequence ID" value="KAL1895792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF502">
        <property type="entry name" value="SMALL G PROTEIN SIGNALING MODULATOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="431"/>
            <end position="659"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="780" mass="89396" checksum="A2A6B22FE00CC78E" modified="2025-10-08" version="1">MASSSTKTAPDSPTASFYAMSDEEEGYSTIMHTKSATGVKLLFCKSKVYIHPTPVARDNIPGYITVLQQKGSATTTSESALADGDSVAKPLSSDLFLAWFPETFLGDDAGLYSKVDMAEGEGPWNKPSLVPPPPTVTENHNLQGHHAFAIPLSSIYSLTVRPPSLGWWYGSIIINSRSGDSFPALFFHDNECQSTIQQKKRRTKESFEVFGANGQVFWGGDEVLRWLKMYVRVERSGPEPNIYLIDASDEDIRNFGKAMEAKRSEREAAKSGNHSSNAQDPFVKFVKEASWNIMERFSRVTTYTRRAAQDVLDNPRMPLQMRRLVQNPDVQTLQEEYDSARIYLARWAMGVAEQSERDRSRRIWTAKDVQELEKTDLGDFEILSGTGSLSLQDRRQPVSIEEWDAFFDPITGSLAKTIDEVKERIFHGGLEAGDGVRKEAWPFLLGVFSWYSTTEERKAQLASLRDEYYKLKQAWWERLDGLGGEGTEGESWREERHRIEKDVHRTDRNIAIFSGDDTPHPDPNSPFSEIGTNVHLEQLKELLLTYNEYNTELGYVQGMSDILAPIYAVVQDDALAFWCFQHFMDRMERNFLKDQSGMRSQLLTLDHLVHFMDPKLYDHLKSVDSTNFFFFFRMLLVWFKREFEWQDVLHLWEVLWTDFLSSSFHLFFALAILEKHRDVILNHLKAFDEVLKYVNELSGTMDLESTLIRAESLFCKFQRMVEAVDKKDNFPIPMASSSSSKATNNNSMEEQIVTPELRKLLSRNVDVFYVSQTKKNTLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6E9</accession>
    <name>A0ABR3Z6E9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_002874</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000061">
        <property type="protein sequence ID" value="KAL1896228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF26">
        <property type="entry name" value="AXIAL BUDDING PATTERN PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="233"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="301"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="415"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="240"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="358"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="455" mass="46245" checksum="C42B1642470743F3" modified="2025-10-08" version="1">MASISMAGPFSKRQLSSGDVVSVISSLLSDVPTADSGSTSTAAQESTSQAVVSTSSAVEEDVTVTVTSGSGATSTVTSDTTQTITVTVVATVTYVSTVFATSTVTADNVATATLTVYTTVTSASNAKRAPMPVYNDLLLPRETGALSKEAPRAVAVPRDAVLVKRATVTVTVIASDNVVTVVPTSTVTSRRTSTISSTSESTITTTTFINAQTTVTVTSTITQIVASITNSDDDETIAPTATDSTSSSGTSSSSSSSSDSSGLSSGAKAGIGIGAGIGGAILLLLGIWYIMKRRRDRPVVSRDEINGGMSEVPMGQSSHGPDTFVHNFPNPHSASAAAALGINRPDSSSPPLHKNHYAPSPASSPSNAGNMGKSPTAGSPPGTAFNHTMPGSPHAATPPAAGYAEMGADERVEIGEGAPRVHHPNAAEIDSRPLNMTHQSGPVPEVYEMPAVTYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6U7</accession>
    <name>A0ABR3Z6U7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BolA-like protein C8C9.11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003037</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BolA/IbaG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000066">
        <property type="protein sequence ID" value="KAL1895815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.90">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045115">
        <property type="entry name" value="BOL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002634">
        <property type="entry name" value="BolA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036065">
        <property type="entry name" value="BolA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12735:SF27">
        <property type="entry name" value="BOLA-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12735">
        <property type="entry name" value="BOLA-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01722">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82657">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="110"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="135" mass="14398" checksum="221A538C536D5799" modified="2025-10-08" version="1">MSVTITEDALKAALIERVAAIHVTITDISGVFIMQQQLRPPVLPNKTNQASPRIVADVPPGGCGQSFTALIVSPNFTGLNSLKRHRLVNSALKAEIASIHAWTAKCQTPEEYERDTGISLQTGPASEDQPPAVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6V2</accession>
    <name>A0ABR3Z6V2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003052</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000066">
        <property type="protein sequence ID" value="KAL1895830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="493"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="604"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="640"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="714" mass="78558" checksum="AF59FDA72EEC9D95" modified="2025-10-08" version="1">MVERQRPTIEQKNKGKKDLYDTSTAGDGAAAATSSPSLNTQKSSDSQQLITNKNTPDMPPPVVQPSQTTLENDNGDDNDDNLSSPPSHSMSPPSSLHATTPRDPAPTEAIEHTSPSRTTPDNEPSEDARHITTDDTRFSSSRRKRNSMFDEAYGATSVGVANTTEDSPHHALRRVGQINPAKLILVGHWRFSTVPDDSHKHSVVCFIDTRDRLRTRVQTMTRSGHPINAQYPMPHGGSWVPFEQIVFEDHLVGLDQAQVKEYVKIRTEALDNSGGEEDVIAAEREAVGLATQRVKYGPQPESGLPIAYGKEISDQRLGLHSSSKRRRTDSSFVQVSQHTADSSAVGPIPFTSVGLAQNLPPLDPLPGTRPTRILIGYWHGSNEPQERDRHAIYGILGQNDMFRVKVVRETRDGRFVDGNFPSGAGALWIHYEEVVLEPHLRSLSRHEVKEYCRVRQWQIDHDETDESREANEAFAVQEAQARVAHGFRTGQITMVSKPPDDKANLVPRISSGPHHYHQLRPAPSSGIRDDDRRSAGARRSLPDSRAPVFRAANEPPNIPRPIAEPSRQLPPPNPSLRASYGAPPPISIQTSAANAASIASQVISASSVGPPPPVRTTTTPTTRMPPLPSASSSNGTRINFGDREESHHASGEWTSPDRQRSSLSTDDAIMYGGIKYEKKKAGPFKDRHVSQGNIISINGEDYVEYRVLTKPTFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7P2</accession>
    <name>A0ABR3Z7P2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1304-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002698</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000055">
        <property type="protein sequence ID" value="KAL1896676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009732">
        <property type="entry name" value="DUF1304"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38446">
        <property type="entry name" value="BLL0914 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38446:SF1">
        <property type="entry name" value="BLL0914 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06993">
        <property type="entry name" value="DUF1304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="119" mass="12295" checksum="F57B6EC168F52C3B" modified="2025-10-08" version="1">MLATAATAALSALHGYIAVLEIFLWTKPAGRRAFGLKAEFAENTKVLAANQGLYNLFLAAGLAWGLVHPDTAFASQLKVFFAGCVSVAGIFGAATSNKKILFVQGVPGLATLGLSILGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7U8</accession>
    <name>A0ABR3Z7U8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glucosamine 6-phosphate N-acetyltransferase</fullName>
            <ecNumber evidence="1">2.3.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">GNA1</name>
        <name evidence="3" type="ORF">Cpir12675_002855</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-glucosamine 6-phosphate + acetyl-CoA = N-acetyl-D-glucosamine 6-phosphate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10292"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57513"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="EC" id="2.3.1.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route I): step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the acetyltransferase family. GNA1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.4" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000060">
        <property type="protein sequence ID" value="KAL1896262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004343">
        <property type="term" value="F:glucosamine 6-phosphate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039143">
        <property type="entry name" value="GNPNAT1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355">
        <property type="entry name" value="GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355:SF11">
        <property type="entry name" value="GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="24"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU365086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="173" mass="19137" checksum="7E61AD1F4EDDECF2" modified="2025-10-08" version="1">MSATELFSTDLISPEVAAQLPEGYIARSLRSSDYATGFLDCLRVLTTVGDVTETAFHERFEWMAKQDGYYVLAIEDTATGKIVGTGALIVERKFIHNLGLVGHIEDIAVAKDQQGKKLGLRIIQALDLIAAKVGCYKSILDCSETNEGFYIKCGFRRAGLEMAHYYEDKTKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8C5</accession>
    <name>A0ABR3Z8C5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000053">
        <property type="protein sequence ID" value="KAL1896918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1896918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="263" mass="30292" checksum="20175AF41ED6A488" modified="2025-10-08" version="1">MSHYSVKSPRTSASNSSLQRHILSSQLDTKRTGKLQIHCKTDSDTYIVQTPGGFREAKKDVLQSSFAGEILLLSFDFWDNIVPFVSRRKGKAASCTCSQNIGKMDNSSTERIVTHTYRCQEQKDPSIRVVAEGPRNDYFCWEEDKVRYFLVSIGDTTFQSSHHNMLKTWPGRFLLYEWPAYNETVLDHMWRDVKMPLRKLEKDVRHKIRSYKTHRGSFGDSETVDDRRSLSFDLFRKPSWSSSFLKRPSISSLGSEGVQVTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8F7</accession>
    <name>A0ABR3Z8F7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Imidazoleglycerol-phosphate dehydratase</fullName>
            <ecNumber evidence="3">4.2.1.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">HIS3_1</name>
        <name evidence="3" type="ORF">Cpir12675_002741</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.19" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000056">
        <property type="protein sequence ID" value="KAL1896645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004424">
        <property type="term" value="F:imidazoleglycerol-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038882">
        <property type="entry name" value="Rcf3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39153">
        <property type="entry name" value="AGR244WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39153:SF1">
        <property type="entry name" value="AGR244WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="71"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="109" mass="12203" checksum="60EEBF9A25234E31" modified="2025-10-08" version="1">MSWASRSTEREAEATEAAWESAYGAFSGGLKWGLGAGILAAVGMKMSPVYRGLTLQFKVYIQMSAMVLGGMIEADARLRMYEARMRQMRRQEAEAQKWNRLMAELGDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8H4</accession>
    <name>A0ABR3Z8H4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Translation machinery-associated protein 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002544</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000051">
        <property type="protein sequence ID" value="KAL1896965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015157">
        <property type="entry name" value="TMA7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28632">
        <property type="entry name" value="TRANSLATION MACHINERY-ASSOCIATED PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09072">
        <property type="entry name" value="TMA7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="68" mass="7159" checksum="5E667EDD2C7CEE58" modified="2025-10-08" version="1">MGGANRQGGKAKPLKAPKKGPKDLDNDDLAFLEKKRAEEKAKKDMAAKAGGRGPLNTGQQGIKKSGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAN5</accession>
    <name>A0ABR3ZAN5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Lipin Ned1</fullName>
            <ecNumber evidence="4">3.1.3.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ned1</name>
        <name evidence="4" type="ORF">Cpir12675_002629</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the lipin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.4" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000053">
        <property type="protein sequence ID" value="KAL1896908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026058">
        <property type="entry name" value="LIPIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007651">
        <property type="entry name" value="Lipin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013209">
        <property type="entry name" value="LNS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031315">
        <property type="entry name" value="LNS2/PITP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057124">
        <property type="entry name" value="Ned1-like_M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12181">
        <property type="entry name" value="LIPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12181:SF12">
        <property type="entry name" value="PHOSPHATIDATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04571">
        <property type="entry name" value="Lipin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08235">
        <property type="entry name" value="LNS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24565">
        <property type="entry name" value="Ned1_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00775">
        <property type="entry name" value="LNS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LNS2/PITP" evidence="3">
        <location>
            <begin position="433"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="94"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="189"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="328"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="643"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="99"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="141"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="347"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="361"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="646"/>
            <end position="701"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="753" mass="83510" checksum="18A4E7AD775D6135" modified="2025-10-08" version="1">MQYVRNLSDSVSTAWNSINPATLSGAIDVIVVEHEDGSLSCSPFHVRFGKFSLLRPFEKKVEFNVNGVKQDYSMKLGEGGEAFFVFETTDNIPQDLQTSPLASPAASPQMSPAKVDELENEPDSFSLDDNSTTNTRRSPKALAASSADLNDDGSLTSLSTSPPDFHIMRAKSDDWQTLKAKPLRSNENLRHSAHPDAHTTQPFSQGNGSPITARSQASSPIASREVIDRALTLSRELSAANIPSQITETGDLMLDMTGFKSNEEDVLKAEILARRILSEELDGNYDIGALFGLDEQGNLWIYHSEEAKEAAMKRTLDAAMCNDNNVSADAVSDPGYQSDSSDISVPPHHHLSHNHRRSESDTGPMQLQSRSSTSASDIAPAGDPNRNYAKTLRLTSEQLKALNLKNGENVMSFTVNRATCQAYMFLWKYDSPVVISDIDGTITKSDALGHVLNMIGRDWTHSGIAKLYSDISANGYNIMYLTSRSVGQSDTTRAYLNGIVQDGYRLPRGPTILSPDRTFHALRREIYLRKPHIFKMATLRDIRNLYGPESRPFYAGFGNRLTDQISYRTVDVPRNRIFTINSNSEVSMDLLSLNTLKMTYMNINEVVDHYFPAVSTMVKGGGEEFTDFTYWREKPRDLDEFSFTASEDEGDDEEEEEDLDEEDGDEYMDDEGLEYEDEDMGSDASIEEEDEYDDDDVDDELEHSVHDLVESAADAAKKAMQSSSAPIPLNSVPDVSAQLITGVKNLSVSREQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBC6</accession>
    <name>A0ABR3ZBC6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Infection structure specific protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000044">
        <property type="protein sequence ID" value="KAL1897542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045085624" description="Infection structure specific protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="217" mass="22486" checksum="F792129AAB1538D1" modified="2025-10-08" version="1">MLSNLLILAAISGLVPAALALHNADFDALAGQVVHNQIVPTPHARVEDRDTQLSDILAMALWIPSSCHDELSFITEAPAPEGALEVYEDTGADPCLTEIPTSLSRDYASYSSKVLSWIFAHNEDVMSLYSCLGTMTETIESTTYCDAIVLTTAEIIASENARETGTQGGSTNSGSAAATATSSGVSATSSTESAAGRVFSGFHAVAVAGIFAVAIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBJ8</accession>
    <name>A0ABR3ZBJ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zinc finger CHCC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002465</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000048">
        <property type="protein sequence ID" value="KAL1897208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.40">
        <property type="entry name" value="q5lls5 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019401">
        <property type="entry name" value="Znf_CHCC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13156:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13156">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-A SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10276">
        <property type="entry name" value="zf-CHCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zinc finger CHCC-type" evidence="2">
        <location>
            <begin position="110"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="167" mass="18152" checksum="512328CF4A2ECC11" modified="2025-10-08" version="1">MSASYKIREVAARSARLAGAARRAFATTACTADAHRSTLVDSSAKSETESTSGGIQQAPNRTSVWANSQIPRNQAMSGPRFEQTDFPAQPAPYSAMALIHEQPVQWTHDKIVVCDGGVNSASTGHPRIFINTDKPKICVCNYCGTPYANDHHRKHIEAQPKTAYPLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBZ1</accession>
    <name>A0ABR3ZBZ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_002161</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000039">
        <property type="protein sequence ID" value="KAL1897817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="23"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="281"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="469"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="282"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="487"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="674" mass="74504" checksum="599C2F853CFB5C19" modified="2025-10-08" version="1">MSDTVDDRDPPPTAPHPNQRRSACERCRRQKLKCSRQNAANQPRCQRCARLGFECVEGRQRKIGRPSRSDVAAAAAAASSSSASSSTNVAATTPSATSGILNAAKSSMEDSPSLSSAHLWQNASSTHISDSGFNSTSISNAPSSKNATPEPYTVELTTRPACSFKVSHSSAMSGPARSSGASFTKAEQPSICLDSFNATSGNINSRFQSFDKQNNCFPGTSANQLPENVATLLDISHADNQQSTTNISNDFNLVAEMLAFDESIDTAWPLDTNAYQNAQAFQRQQPEQQPKQQPQQEQQEQQQEQQQQQELDEGYQTHQTHYQYLYTQQHYQSLSKAHPRTRSPNSGPQSFFFPFPTPFHQSFNNSNSRDYPPNPLMAGPIAMAPIPKSIFPKKNSPLDFLDNLSAINTSFQQCVYLIRQHSEALNIDLLISIESPLAINGISMIKRGMLNIQELLRLLINLRNSISSITEDDQSSDPQPQSARMKPPVPPPPSIKMPVPSPVLESVQRVIQEASSSSSETATTMPKVLDTPTSLAIISCYSQGLFFLETIVIHINYTLENAGVRPLYTLPTERCGIISFQDHLMQGVIFAQLVTNVVQRLDDLMGIPLKDPSIFSLNSSRGLLNEHQIKMLWLELRSERLDWSPRSSKLRKDLTHMKGTLVHLLSKNMTQGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDP0</accession>
    <name>A0ABR3ZDP0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF3824 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000029">
        <property type="protein sequence ID" value="KAL1898758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35487">
        <property type="entry name" value="DUF3824 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35487:SF1">
        <property type="entry name" value="DUF3824 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="496"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="665"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="739"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="392"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="444"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="457"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="496"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="519"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="534"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="739"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="811"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="842"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="876"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="955"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="975"/>
            <end position="992"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1150" mass="129894" checksum="87DA59346B6868F5" modified="2025-10-08" version="1">MDRRYSRQHVSSDDEGRTTTTVVRRYKVTAPGIVTHHDTSHRRSKSSHRATADQPQTQLVSLSSSGGGPQPDIIAAAASSNMAMVYKKDWSRERHEREYIPSEKNKVVVHGYDRSMARRRGRDYDEACRDEYNGAIRHYHRHHYQDYDQEAAEEAQRLEDYERANRWHQHNRCHTTIRRQRGSSVGSTLSRNSDDDHHQKRYMAEGALAGAGVTALLQRRDEFGDLPEHRGRKVLVGAALGAIGAEALRRAKSAHESSRGSSDERHGTLKKALGAGAAALAIAGTAQLIRNYREENDSESRSRSRSRSLCTGRRRSKSCLYRRQRDYRASGSSAQSDVEYNYTEDRCKSCHRRDCSGHHQNISGRRGRSRTRSRSRSADSSDRKYRRRRNATKVAAGTIATAALAQRVRHRHHSRSHSRSESSFYARSDDEEERRRHENHRVAKVAAGTAATAAAARHLRNRSLSRSRSRSRIRTGAEVAGAGLIGAGAAKLYNKIRRRARSRSKSRYRSRSRSRSRSRSISSPRSTSGSYQPRRSRNWNRRRRYNSDEDAPCYLDFDYDDPHHQPTSHKARQKVYNHIRGALFHPEPTFSEVSGPVMELDMVPQAITAGPRMSGALASSDDGFVPDAPVGRPKALTDYEANPIPMPEPIRFGYDKGDRAVPARSIKPHKEMEEKLPFSMPQNDRPRRRNRSITRDPVAHRQFSQDSALEADVESDDEWYIPPQGIYNLHGLKTEAAELERPNERQDSERQNEQRAFERTKAEQRQHYLDADLHHERGQVGDFTQEGGYIHPQDYSPGRNFDRTQPRSRSRSLSSSWSDIQSSNIPPPQDRRGGAPEFKAPTISSCNSSPKSSWFPLQQVSPKGTSNASALALGQEPTTEESLGPSTTSRQSLPQTYKPYREPQSFFSKGQMDYFSPKSEASHERYSSSNATLGAKDDEGRGGNSISVPPYPVTPVTNDTSAPKNVTSSLSTSPSKERSEMHQNERPKKSDTFPRPLLKIPQIETSPRPSSAMSDKTVTFGPMSPQSLRTLQELHAARPSDEASHAESEIEELPPRFDRFGQLLAFYGQNHQGEYRYRGDNTASEKVDYISVPDSHVESMWSMMSSDPEVVDAIADNMESNENSRHVGVTSSMFSWMLGRSSQRQVRSFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDY1</accession>
    <name>A0ABR3ZDY1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RWD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_001922</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IMPACT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000033">
        <property type="protein sequence ID" value="KAL1898377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.30">
        <property type="entry name" value="Impact, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023582">
        <property type="entry name" value="Impact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001498">
        <property type="entry name" value="Impact_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036956">
        <property type="entry name" value="Impact_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020569">
        <property type="entry name" value="UPF0029_Impact_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301">
        <property type="entry name" value="IMPACT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301:SF25">
        <property type="entry name" value="PROTEIN IMPACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01205">
        <property type="entry name" value="Impact_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00910">
        <property type="entry name" value="UPF0029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <keyword evidence="5" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="RWD" evidence="7">
        <location>
            <begin position="7"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1898377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="295" mass="32097" checksum="5D237F1CF9E29067" modified="2025-10-08" version="1">MSEDFIDEIEAINSIYGDKTITPISGSSPASYILTLPTTKSSLRMTFHETYPETEPPIINGLHSAGDLTKRGSGARDVRLFQEALGTSYVPGAVCLFDALEELSRLLEYEAAAEKAAELEAAEGLYEEVRGEGEGQSKRHTQTEDIAVDLAGPAPPWTLSMPFMENKSTFLARAARVDSPTLAAQYIAHLLASDKKVRSATHNITAWRVRGPTDGSGKPGAVYQDCDDDGETAAGGRLLHLMQIADVWNVVVVVTRWYGGLKLGPRRFALINNAGRDALVRGGFIEEKETSKKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE69</accession>
    <name>A0ABR3ZE69_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Meiotic expression up-regulated protein 6 PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001635</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000027">
        <property type="protein sequence ID" value="KAL1898975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039712">
        <property type="entry name" value="Meu6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039483">
        <property type="entry name" value="Meu6_PH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42073">
        <property type="entry name" value="MEIOTIC EXPRESSION UP-REGULATED PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42073:SF1">
        <property type="entry name" value="MEIOTIC EXPRESSION UP-REGULATED PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15406">
        <property type="entry name" value="PH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Meiotic expression up-regulated protein 6 PH" evidence="2">
        <location>
            <begin position="79"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="298"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="363"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="493"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="510" mass="53487" checksum="0883A048E79B28BC" modified="2025-10-08" version="1">MSAEQKPTETVEAVAPVAPVSAETPAVEATETTAEAAADPVSTEDTADAPVEEAEAHKQEVKPIEEGILEHKGASFPKNFLYKKDNFWFGTDAVEASVLAAYRKHEKNSELSFEISAWAAATGKGLLFFGDRASPSVISLVDVAEPTTEGVSKFTVVAKGTKYLFKAANAADRDNWVSQIKEKTAEANELAKTVPETEEYKAAYEALKPAPKVEEAAATENAPAEEAKSEEEAPKEEATEEPKAEEATKEEGSKRRSASRKRVSILGLGFLGGKKEKASVSEEAKPEAAAEESKAEESPAAETAPAEEPAATEEAAPAAEDAPAEEEKKEEVATTKASKRSSVFGFLKKAPKAEAPKEEAPVEEAAPTLDAPAVETPVAEAPAATEEASEAAPAAAEDSAPEQVKTERRKSSLFVFGKKEKTSSDDETEKTEKSGFSLGKLRATIRGRKPAKAEAAAPAAEVKEEEEAAPEAAKEEAAAAPATEEAKVEESAPAKIEGAAPAAPVVAATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEB1</accession>
    <name>A0ABR3ZEB1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Vacuolar inheritance and morphology protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">VAC7</name>
        <name evidence="3" type="ORF">Cpir12675_001903</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000032">
        <property type="protein sequence ID" value="KAL1898436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024260">
        <property type="entry name" value="Vac7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28258">
        <property type="entry name" value="VACUOLAR SEGREGATION PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28258:SF1">
        <property type="entry name" value="VACUOLAR SEGREGATION PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12751">
        <property type="entry name" value="Vac7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="451"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="654"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="319"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="654"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="680" mass="74282" checksum="27180A5EF1119F31" modified="2025-10-08" version="1">MQRAQNNAPGRYISSSANSSASEMSESDTDDHESAGLRTPTMNNPNPLATVQEASQPNSPGHATQDTAMTEIHTHLVTDDSQNQNQELQTPQTPSSQDSDNMSAASVRTIRARNVAPYNDSDHTTSQNDARKPSTSVPQPPMMSRQSSAYSTFNKTKPTTDGSSMIVESETVTSVPQIALATIPQGPSGTLRAMPSTETIRPKKDRKRQTRKQPMNPASSKAEVFEYKVASAVDEADDSDSDETFVYDSNPHDGPRRYHHSRTPSTTSMASQVDRPMRSIHSVMDVPGPSTSSKKNMKFANTYNNASDTLTGDEDGRGSSRSNIGSSRNSTRHQHHLNKYGRNQNSHASLFDNESPFVNPARAKMQANSRQNSGPPSPRFLTSRSQASRQTGSYNLSNAYDMDETGPDDERTPLISYSRSNRPGRQSRRGPTPRHIESQTYRSRPSALNRLAACLVVTMMVLVVITGAIGFMFATSQPLTDIKLVAIENVIASEPELMFDLTIRAHNPNIVVVTIDNANLEIFAKSVHAGTDADWYNSPSGGPGDKFKFETLDEKEVHAEDDPPDDMPDESAPNMRLGTIQEFDSPLSFEGLFFHKGLSVSTGGVRLPLPGNSTTGGSERWGKVIQDDFDLIVKGIIKYYLPLSQRMRSVSISGRTRVKPNSASNPSLKPNITMAGSLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF12</accession>
    <name>A0ABR3ZF12_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">WD repeat-containing protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">WDR6</name>
        <name evidence="8" type="ORF">Cpir12675_001629</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat WDR6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000027">
        <property type="protein sequence ID" value="KAL1898970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051973">
        <property type="entry name" value="tRNA_Anticodon_Mtase-Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14344">
        <property type="entry name" value="WD REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14344:SF3">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101908">
        <property type="entry name" value="Putative isomerase YbhE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="265"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="808"/>
            <end position="826"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1898970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1172" mass="125309" checksum="BA4AB1F8500AE7B8" modified="2025-10-08" version="1">MASQTPPLSSATATATAPQPRLRRHLALLPVTALAFYTAQHNGRIYVLAAEDNVLNVYESRPRDAASAPCCALKVFDAQAIHGIHIGTATTSETNPESVLAPILIWGGQSVTLIPSLMLEDAIANGRMLLDTCLLVETKSPDWIYDGLISPFDPSQGLLVLAHNEVLPVTLAANHSIVLGSIFSISRPILYSANLCWTAPTTVLVAAGTVFGEILVWNYHIADAHSTKPATAELLHVCTGHEGSIFGVQISSEFTGTDPTSRPLRLLASCSDDRTIRVWDISERASSPARTSTASAAEPLSSSNTISALHQPRETGFGDAPGALANEGESPLAMAMGHLSRIWHVKFPSTPLVSSADKFVLPVYSFGEDTTVQLWHFESTWAALLNETSASKPPSTLKHIASYANHDGKHLWSAALLGDSPLPQIATGGADGKISIIEQGNSREADCSGNHMDVMVLQDASPNSGSKDSDGLRQYTFVTDDCLVATTKSGKLTTGTFSQGELDTAAVWVDVATDQDTSDNLRSCTTMTSLGTGHAVLGTSGGHIYVYSLGKGLQKLATLSGKIMQLICLNTGARNSAIQVLVTVFNSPETKILTIDVDAGSIASELILQGIDERFIVTAASFVGDFLVVGSRSGFLSVLCTTNNNNYQYKLVSEIPPRAFDAVACITALPGHKAAESPCFLTTGRDGKYRIYRISAVTGMASLFHEVSLPFGPVVETAWFSSESLDLIICGFRSTRLVVWNESKREQIASVECGGAHRVFAHTASADPNRLRVAFTKASKVYVHSQLKPAFRSLKKGVHGREIRSVAPCGRYLASGSEDTTIRIWEYIGDKTVGRGSMSCVAQLSMHVSGLQSLRWLANEWLFSSSGNEEFFVWRIRKLDAKISGLAAMFQGQLPDKSRDGDLRITDIDVRVISMADVDNPEFRIHMAFSNSELKTYAYSPSSGFRLLASGNFTGACLLQIRGLEKAGAGVGDDVLPPVLTASTDGHLALWEVSRRCDSDVSSGVEKYEMTLATTTHQNSPKAFDINYFETPDGAHGYLVVTGGDDNAIGIVRYVSSTLGSSTAPTPSAAYKVTGKFAIRGAHAAAINGLAIGSRGARPTDDTCSFVSASNDQRVKLWRVRGTQSGEISVEMLQNAYSGVADAGCIQELDEGRGFVVAGVGMEVWTVGDEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFF2</accession>
    <name>A0ABR3ZFF2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_001684</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000028">
        <property type="protein sequence ID" value="KAL1898932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045018">
        <property type="entry name" value="Azg-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43337:SF3">
        <property type="entry name" value="PURINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43337">
        <property type="entry name" value="XANTHINE/URACIL PERMEASE C887.17-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="202"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="337"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="337"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1898932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="376" mass="41826" checksum="8A72459B3548938B" modified="2025-10-08" version="1">MGLNAYFAFQVVGPNGSGSIPYSLALTAVFVEGLIFVVLALTGMRQWLVRLIPATIKTATGVGIGLFLTEIGLSYAAGIGAITGGWKSTPLALGGCAPELIDSQTQMCSSGLMSNPKMWVGIVAGGILTAFLMSFRVKYALIIGIAFVSLLSWPRNTAITYFPHTDEGNSRYEFFKNVVSFRPIKHTLAQLDWDFGTNGSQFALALFTFLYVDIIDATATLYSMVGCMMIRQITQINWKYIGDILPSFVVMTFIPFSYSVAYGLIAGVFVYTALNSMIAVAVWASGGRLEPREYDMKEYWTWKGMGRQPWFVRAVRNRGRFWYDQDDPTKQGYNLEEDHDHGRRSFFETPPPAQPGERDKDGIAVQMPERAFTTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFY4</accession>
    <name>A0ABR3ZFY4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000021">
        <property type="protein sequence ID" value="KAL1899620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="600"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="200"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="313"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="788" mass="87082" checksum="121E6A95F9E97DE1" modified="2025-10-08" version="1">MAIWHFRKKSTDGRKRPRSGNSLSDLEGSSPSPSPPQTDVVLAQDTEPSATHTQQPRTPKRRSTLKKKRRTEPPSQPRTHGDVSTGHARAFSFTEDQPESISPQVLPEVIVQDNIVWEIPTLSPHRPERSSRLPKKHYRRDPARETEIQAISTVLNTRPNSTCSRQISRKTSSKHKHSSSLQHRYTSDDRDDMEFPSAESLRSSMSSDGSDSAAYLVTVLGSLAPRPTLKCTSRPNWSPNVDRTSVSRAHRSIDLSPTPSNIKSRARINGLADAFDSTDLRAIMERDQRRRERKIIRDQERAAERIARKKAEQAALAEQAAASKSTPPRNMERGVLGRELMDPVEIHPGPSTPQSMEIDELVLKESSLLNNSRPATPESLVSCEGADASSVLSVVENQDYGMDNVSMEADVGAVISSPTYPSSELLPEGLASNETVDQPKIDRNRLEPEVFVESEPQPILQTRPHASSVSFTPTLSPSAIIASDVDQSSTSTRRRSLRTMLRWGSRKRKKTQPVFINTSRDAISIETARSREFVSSSIYDSSDYELPIPNNPTRIVPRRTRSRFREDLPELPISPPASPLRQERDLSTIMSVSEHMSVLYSSTSSPTSTRHGRHRSIDALNCSSPTPPERQVQNELEGDEQLTDTPSPEPRSISVASVGSESEWLAGRLSSRNLPISRSTSRRYADSPELDCDNEAANKVSTEFGFVRGSSSQAHYTDENVRETVGQERGGLAYAMGDAKAPANTDTVAGVSTLADTRKNTTALEANVLQQPLDAEDHQPNTGSGNMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFZ4</accession>
    <name>A0ABR3ZFZ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peroxin-7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PEX7</name>
        <name evidence="12" type="ORF">Cpir12675_001726</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Peroxisome matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the WD repeat peroxin-7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000029">
        <property type="protein sequence ID" value="KAL1898723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044536">
        <property type="entry name" value="PEX7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46027">
        <property type="entry name" value="PEROXISOMAL TARGETING SIGNAL 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46027:SF1">
        <property type="entry name" value="PEROXISOMAL TARGETING SIGNAL 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="5 11" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="103"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="247"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1898723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="349" mass="37973" checksum="4DA62901FF0EF319" modified="2025-10-08" version="1">MATPMLEFGTPGFNPYAVRYSPYIDSRVAVASSANFGIVGNGKLFILGLGPRGIALERAFDTNDAQYDLAFSEINENQLIVACGDGSIKLFDTTAGDFPIMSFNEHNREALSVAWNPVTRDNFASSSWDGTVKLWSPTRNFALRTLPIGSCTYGVSFCPSNPSIISAVSSDSNLRIFDLRTPVSAKYHLTAMIPIMSKPPGEPQAPSEVLCHDWNKYDHNVIATGNSDSYVRTQDIRNPSGGALSLMKGHGYAVRRLTWSPHVSDVLISASYDMTVRLWNDASKIGGMPVPGRMGRQLGLMNRHSEFVTGVDWCLFGVGGWVASAGWDERVLLWDANALMAGAGRAPTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG88</accession>
    <name>A0ABR3ZG88_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_001222</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000018">
        <property type="protein sequence ID" value="KAL1899723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02883">
        <property type="entry name" value="NUDIX_Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047168826" description="Nudix hydrolase domain-containing protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="72"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1899723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="205" mass="23067" checksum="751654BBD6E6D5F1" modified="2025-10-08" version="1">MKFSILQLLSITFLGSFGPTAVHADSGLLSGDWGSLQYFSDVGIGAWKLPEGVTYVQDDDDNEKDGTVYLGNVRIRCGVVPYDEDDNVWMIASRGNFANVGYIFPRGGYDHNNDADMEDCVVRESKEEGGFMINRDSISPLGISSDRGTYWFKAKIDSFVDATDSQSRPANPTWFDKEEARTEMKRPQDRPSKKREMRVALYFAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGE8</accession>
    <name>A0ABR3ZGE8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein transport protein SFT2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SFT2</name>
        <name evidence="9" type="ORF">Cpir12675_001413</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Nonessential protein required for the fusion of transport vesicles derived from the endocytic pathway with the Golgi complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Golgi apparatus membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the SFT2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000022">
        <property type="protein sequence ID" value="KAL1899377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007305">
        <property type="entry name" value="Vesicle_transpt_Got1/SFT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011691">
        <property type="entry name" value="Vesicle_transpt_SFT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23137:SF36">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN SFT2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23137">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04178">
        <property type="entry name" value="Got1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1899377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="210" mass="23067" checksum="B445437725AA5024" modified="2025-10-08" version="1">MASASFRDSMNSLGWSRREPAPIVTAAPAQSGFMSSLQSINPFGNSGYIQLPSDQGLPPPVQSSRQEEGFLNLSTWDRTLIFAVCNIAALVCFSLSFLVITLRPRKFVILWTFGSILFMASFAAMMGPMTYLRHLMSGPRLPFTAAYFGSISLTLYFSVGLHSTILTLFSAFIQIGALLWYLFSYFPMGSAGLRMVSTFGARQATSWMSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI39</accession>
    <name>A0ABR3ZI39_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7704 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001201</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000017">
        <property type="protein sequence ID" value="KAL1899977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056121">
        <property type="entry name" value="DUF7704"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37019">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37019:SF1">
        <property type="entry name" value="EXPERA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24803">
        <property type="entry name" value="DUF7704"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7704" evidence="2">
        <location>
            <begin position="642"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="791" mass="86839" checksum="8AF633C9D2CE37F7" modified="2025-10-08" version="1">MSTAIPTSPRSPAPNMTSIMGAPPQTPKSKSRGPSMYGPVTPTTVAESWRLVDGDFESFDAHFLPETTSPHKLGGGTPSFRSSASFPASDEGLDMSQRTVEFTEDERAFRDLREPMEPTLTPGRRRLLRAEEVTRGYDDQLTTPRRGDDGLRENQIRYRQKQQQRHQCAMSEYENAELDHNHDCDEDYTHAPPPPRRRSQNTQATKAVLQDVLPGFIFETLTWTLGLIGHALRFVQKPLAALLAVYLFASGLLFLQSILTNSLVSTLSPLCRVPGISSLDVCSSPLINKNGILAQVEFESLMSVQGKFEHVLEKSSSGVSLPLEMKQSEMAVRDLRALVHYSDLPARDEIVTHFDGYIDIARKTARHLQLFNTHVGTAVDAVISINRWTLRFLDSARSVEGSNGFDSGFGGVDGGQARNSVVKALMMPIEIVVGGVPAHRFSEAVLLEKYIEHTAYVSDHIARLIVEAQYVLGLLTSAEDHLLLIYAVASREERAVASQRDAVKWSLRTLIGANNKALHGFDEQLALLRRVDNQRSQAVAQVLELIVELESMQASLETLRDRVAAPELAQQTMGGAKIPLQVHIDTIERGIERLNMARGRIRSADNEKLQQVLEHGGTVGRMSEADSHIAVVMSSTLVTATSTFPAFVRLALTIFEPLTALNGAYLALWDAPALIQVLPRTLDGTVPEPPADSAYIFSRIAAGWLLHAALGRAVLRIADDAQLWHAVGAAMLLSDAVFVHATLQGVGGLERWARLHEWSVKEMAANVVTFGMLAIRLWVVGSGGMGKVKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIJ7</accession>
    <name>A0ABR3ZIJ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Polynucleotide 5'-hydroxyl-kinase GRC3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Polynucleotide 5'-hydroxyl-kinase grc3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 13" type="primary">CLP1</name>
        <name evidence="13" type="ORF">Cpir12675_001148</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Polynucleotide 5'-kinase involved in rRNA processing.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of a pre-mRNA cleavage factor complex. Interacts directly with PCF11.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the Clp1 family. Clp1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051734">
        <property type="term" value="F:ATP-dependent polynucleotide 5'-hydroxyl-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1030">
        <property type="entry name" value="Clp1, DNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.330">
        <property type="entry name" value="Pre-mRNA cleavage complex subunit Clp1, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03035">
        <property type="entry name" value="Clp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028606">
        <property type="entry name" value="Clp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045116">
        <property type="entry name" value="Clp1/Grc3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010655">
        <property type="entry name" value="Clp1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038238">
        <property type="entry name" value="Clp1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032324">
        <property type="entry name" value="Clp1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038239">
        <property type="entry name" value="Clp1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032319">
        <property type="entry name" value="CLP1_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12755">
        <property type="entry name" value="CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12755:SF6">
        <property type="entry name" value="POLYRIBONUCLEOTIDE 5'-HYDROXYL-KINASE CLP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06807">
        <property type="entry name" value="Clp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16573">
        <property type="entry name" value="CLP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16575">
        <property type="entry name" value="CLP1_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Clp1 N-terminal" evidence="11">
        <location>
            <begin position="22"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Clp1 P-loop" evidence="12">
        <location>
            <begin position="131"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Clp1 C-terminal" evidence="10">
        <location>
            <begin position="342"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="134"/>
            <end position="139"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF06807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1900042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="477" mass="52111" checksum="DF667229D0AB98F4" modified="2025-10-08" version="1">MSIPGLGHIPDDTPVTTNRIIKLSPFWEWRFEIGFTSQVTVKLVNGTAEKDGTELAQKQPYRFTGLKSKIFTWTGCELEIDGACLDEFVEEYATAVDTPMNAYMNLHYKLTSLRANARHEGTKGPRIMIAGPPNSGKTTLVRTLTAYATRCEEQPLVVNLDPKDSMLSVPGTLSCSVFAGVMDIESPDGWGSSPSSGSSVVPVKAPAVFYYGHSQPDQDPITYRNLVSNVAGMVTTRLSEDSDVRGAGLLIDTPGVNGQDRAGIDCLAHVAEEFSVVLDSSQRLYSELSKRFKNTTTSLGDSITTILLDKSSGVAERNESWVSQSHQAAIKHYFFGDSNQTLSPFTQQVDVSGLTLFQIPERKSQAPSPKPQILDDCLDRTRSNQRLLDSYVTTGHSPLVPTQLTPALEQWTLTIMNASSRDLPEAIRVSTVKGFVYVAQVDSDRGKAKILAPVAGQLGDHPMIWGKWPEPNVNLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ53</accession>
    <name>A0ABR3ZJ53_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Velvet domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_000758</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the velvet family. VelB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021740">
        <property type="entry name" value="Velvet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572:SF3">
        <property type="entry name" value="VELVET COMPLEX SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51821">
        <property type="entry name" value="VELVET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0749">Sporulation</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Velvet" evidence="8">
        <location>
            <begin position="223"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="60"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="118"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="196"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="548" mass="60458" checksum="189D6D6ADB49A06A" modified="2025-10-08" version="1">MNHTGEPPADVHSAGPYESHSGHPLPHYPQQPHAIHSTSQQSQSQQHHQQHQSQPQQHQHQQHQQHQHQHQHQHQHQQQQQQQQQNIHNIPPPPHSMHRLPSIPSAHSQHAPPPPPQQQHSQYQPQQQSSLLSPSSQQQQQQHAPPHGSSGSVAPTADYSQPAASLHHGQMAPPHSQMPPQQTYVPQPHGGPLSHQGQQQLIQTHTQQQQQATMHPLADLVKVYQGRKYKLVVVQQPKRARMCGFGDKDRRPITPPPCVRLIVTNEEDGRPTNDNDIPYLCFVCHVSLWSEDGTNELDIVRHSSGNPSISSTTTASYASIQESTAPPYNQMVSNSRQNSYMPQTGNYGNVPAYAMNYGQQPAAAPASYMTNGYAPANTYYPNNDYRGSMVPNVMGGNNMPYGSSYGAAPPQDQPTVVTRSSGPHGMFTRNLVGQSVVSAQRLTDTDDKVGVWFILHDLSVRTEGNFRLKFTVVNIAADNNSSAVTINQGSVPVLASCFSDAFTVYSAKKFPGVCESTALSKCFASQGIKIPIRKEGGADKNNNDEDYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJD1</accession>
    <name>A0ABR3ZJD1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mtf2-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043837">
        <property type="entry name" value="Mtf2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040009">
        <property type="entry name" value="Mtf2/C5D6.12-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39468">
        <property type="entry name" value="CHROMOSOME 7, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39468:SF1">
        <property type="entry name" value="MTF2-LIKE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19189">
        <property type="entry name" value="Mtf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mtf2-like C-terminal" evidence="2">
        <location>
            <begin position="207"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="410" mass="45266" checksum="AB63838477C01090" modified="2025-10-08" version="1">MSRALRLPFWAAVGGYIFPQTSYSTLSRSFSSSAARRDDLIDKLSQHQTESSFSKSSSSSSATPNSALAETPSNVLAEVPAEAPADSPIESPAETFSALDSVLPERTVSTITPTEKRVFGEIFDSLATTKQTKVSSLFKKSPQRRHRNPWSREEILQMYPPSLRLAVESSFLEENRARDDDLPEAELTDAEKERLAALDTQRVAEVQRVKALFEACRSDKQVWTVLEKEVFLLVQKLGIAPDLPDKTSPTPDTAALEVHGPIFPQHILTAAQRLVYDFTRPSPLALAILPRLKQLGLAAYVLGASTPLYDELLRVSWALNGSIPDIIDLLSRMRDDGLAYSADTLRAVDEVASQIADVKDAVNNFAEPALGMPAFDVQARKALMKEYSLIESAVKAAREETDQEVGRRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKT7</accession>
    <name>A0ABR3ZKT7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000544</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032922">
        <property type="entry name" value="SON"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46528">
        <property type="entry name" value="PROTEIN SON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46528:SF1">
        <property type="entry name" value="PROTEIN SON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="418"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="555"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="338"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="439"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="626"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="641"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="671"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="696"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="728"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="778"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="854"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="889"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="904"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="935"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="963"/>
            <end position="973"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="973" mass="108016" checksum="4CCA55E7E196035B" modified="2025-10-08" version="1">MATLSDAQKELAGLLAPDDIPFKLRCANCSKLAINAFRLPCCEQPICEMCQASLPSTCPICEHSPLSADDCKPHRSLRTTIKVFIRTEEKKRESMKPKEPESDADANLEPTIVPESNPKVETVLDDAETAPAADSQLALGVQSSTGSPGASAETAVPDEAEGQSEGPDETAQTEKPGDGENNGALDNLVVNEEVKKDSADGTHKNNEIAIAVQPEQPSDEANDAKLGSGTTVNMGFGPDGFNQMQMMMAMQNNMATGFGGFPMMGMNMDPMMMQNMYMNGGFNSGIGMNSMNMGVGGYGMGSNDNWNDQQQSWSFGQDNYNHANNQSMAPGDFGNGNGNTPNSSNNNNNSNIDTENGVATVDDNNGSAAATVGINGTANGVMAGPGGNMNGNFGPGFQPGFAGNRFNDWRGNYGGNYRGRGRGRGFQQNGFGRGGRFGFQGNPYWGGQQQYPGQPQAFSQQHQQHQQQQQQQQQQQQHGNRPGSAGVSSHSNTGSVTGGDGIDQPMQAGEKAENGIGNGDVNGQGLCDNANGKAEDAISQQAANANGSAQWNWRTRHANGAPPLNAPTGPKSMRQSGRGGRGFDDREQVEQDAATGNVEDSRSSSPKRSHIPASHRDRNDGDDDDQGRSESRDQDADGQRSSRRRRRHRAHSVSSQTTAHDGNSSSRHHRHEGDATVDTHDDDRDERRRRRHRSRRRDEKSDDKMQADRARSSSPTESRRSGHRSRRDKRERSKDRDRDRDRDRDRDRDRDRDRDRDRARSDKHRDDESRKKHRSSHKDRPRDRDRERERSRDGGDKEKEREKDRDSERDRDRPRDRDRDRGRERDRDRDRDRDRERERERDKKKDKDRRREKRREGRHASKPDATTDSKRASSKADGAASRTATELVASTVPAAATAATTMDAHAREREERNRERLLKETQRRAGLASLVGSKRGREDGDDGRRGRRKGRKSDTINYDDEERPSRRLDTDQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKW1</accession>
    <name>A0ABR3ZKW1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">endo-polygalacturonase</fullName>
            <ecNumber evidence="3">3.2.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">PG1</name>
        <name evidence="15" type="ORF">Cpir12675_000851</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(1,4-alpha-D-galacturonosyl)n+m + H2O = (1,4-alpha-D-galacturonosyl)n + (1,4-alpha-D-galacturonosyl)m.</text>
            <dbReference type="EC" id="3.2.1.15"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.15" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050434">
        <property type="entry name" value="Glycosyl_hydrlase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31884">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31884:SF1">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00502">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9 13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045084327" description="endo-polygalacturonase" evidence="14">
        <location>
            <begin position="19"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1900716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="360" mass="36583" checksum="3249A2BA375F59C2" modified="2025-10-08" version="1">MVSPTLFVLAAAASIASAKPVLVERAGCTFTTAAAAISGASKCSTVTLNNIAVPAGTTLDLTKLAANTKVIFAGTTTFGYKEWEGPLISVAGTGIEVSSAAGAKIDCQGQRWWDTKGSNGGKTKPKFFAAHKMINSKITGLKVINTPVQAFSINEAKNLGVYDINIDNSAGDSGGGHNTDAFDVGSSTGVYISGAYIRNQDDCLAINSGTNITFTNGYCSGGHGLSIGSVGGRSDNVVSGVTITNSQICDSDNGVRIKTVYGATGSVSGVTYSGITLSNIARYGIVIEQDYQNGSPTGTPTAGVPITDVTIKNIKGTVASSGTDVYILCASCSKWSWSGVSVTGGKTSTKCKGIPTGASC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL25</accession>
    <name>A0ABR3ZL25_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000634</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000008">
        <property type="protein sequence ID" value="KAL1901145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="237"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="742" mass="81692" checksum="4450D0B18366C88F" modified="2025-10-08" version="1">MTPFTPIQKLSKWAYIQQWVNDGKTPNGQSPTATTNDKDIGEATVNILATAAPPPSLSRPYSRSSASFSSSNGLALPFEHSPIARVSKEEGGILSTLSLSQYDAERYIEDHFAGVTFSPRPQKAVWDAYPTSFTPTAHEKHLSSQIETDIIISRVDMQCVVPKVVSKHQYALQLAFKVTSPQALKLLRINDIVYMRLLDNSNKALLKPRTTESGTRNYSKKVQHSVPKPSTYDKILSSSPSSSCLVSDSQPAQHSATSGTASPVFSENSPSISKPGDRNASDLVSSSGSHSALSQHMASETFCQFREREFNARVKLIDHETGIITVEVSGISFLDPRGAFKVTVLPGSERFADCRLSLALCQQAMKQELDIEALQRNVITQIRNSWMHNMLYPTTEYGVSFRNTELITNYISRGLLPEQKYAVSRAVANNYGTIPFIIKGFPGVPYTPALVECALQILQKRDHRHSVLICTKDHESADAIVAQMAPFLGPGQMLRLMPSDILASSKSPISTYYHIKDNRFALPPPGIMMQYQVVVARCLDAITLTNHRLTNADLFVSAVSGARNLKGGITRVSDPFSIGGRPDYSLHWDALIIDSACQIPEHETAIPLAIMAPPTQEMVLVCNVNIKSQPQVILGGEDSSKPIKCSPVAGSALNESWFKRLWRRPVYSMNDYALGMSLEKAFHGDSIEDSSQPAFFEMKSLHAPQDQDTWSKSGAGNHRLDVRKALSEFHAQIPRIPGTGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLP5</accession>
    <name>A0ABR3ZLP5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Dihydroorotate dehydrogenase (Quinone), mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">URA9_1</name>
        <name evidence="8" type="ORF">Cpir12675_000890</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF113">
        <property type="entry name" value="MEMBRANE PROTEIN, MPV17_PMP22 FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G13840)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="68"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="136"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="90"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="405" mass="45028" checksum="5E0D0E3CB8F7B669" modified="2025-10-08" version="1">MATLLFRHGLRPLRLAVRPLHQQQPHQPHTYPPPSQLHLSLHNQLQAHLQAHLQTWALQVRCQSTSTASSASVRGQAQDVAGQKTARSTQQQQQLQQQQQQKHQQCEAEPDADLNALSLTSAKTVQAQVVNASAAKSDVSLAPSSSKPSETAPETAQVQATPPITPSADVIRFPILQRLGPLTEMVKAYGRQQRKRPWTTQLWTALVIYFCADVLAQSIGGQQYDPARTGRNLIIGFCVAIPSYEWLIFLGNHFNYRSRLVSLAVKVFIAQFFFTPFFNTYFFSMQALLSGASWSDIVAHVKATVPTSCLNSCKVWPTVTAFSFAFLAPEYRNVFNGLVAIFWQAYLSFLNRSAQEDVEKAEAGLRDMTLRVANVDPLVINNGPTQADLVDKLTEELTEEDVETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLQ1</accession>
    <name>A0ABR3ZLQ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">GPI ethanolamine phosphate transferase 1</fullName>
            <ecNumber evidence="13">2.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">MCD4</name>
        <name evidence="16" type="ORF">Cpir12675_000333</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Endoplasmic reticulum membrane</location>
            <topology evidence="1 13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.-.-.-" evidence="13"/>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16020">
        <property type="entry name" value="GPI_EPT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007070">
        <property type="entry name" value="GPI_EtnP_transferase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017852">
        <property type="entry name" value="GPI_EtnP_transferase_1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037671">
        <property type="entry name" value="PIGN_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12250:SF0">
        <property type="entry name" value="GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12250">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL GLYCAN, CLASS N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04987">
        <property type="entry name" value="PigN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 13" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="462"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="499"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="553"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="589"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="616"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="640"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="681"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="718"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="766"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="838"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="880"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="912"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="943"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="domain" description="GPI ethanolamine phosphate transferase 1 C-terminal" evidence="15">
        <location>
            <begin position="451"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="986"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1033"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1122"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="989"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="1122"/>
            <end position="1132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU367138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1901643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1145" mass="126588" checksum="B9CFE2849F960537" modified="2025-10-08" version="1">MAGFPRFGFLAIAVVFHLVYIYSIFDIYFVSPIVSGMRLYGINRSSSTPAPADRLFLFVGDGLRADKAFQSHPEPYPESPEDLVPRPLAPFLRSRILDHGTFGVSHTRVPTESRPGHVALIAGLYEDVSAVTTGWKLNPVNFDSVFNRSRHTWSWGSPDILPMFQHGAVSGRVDADHYEPEFEDFAGDATKLDLWVFDHVQDLFKAAATNHTLDRALREDKVVFFLHLLGLDTTGHSYRPYSKEYLNNIKVVDKGVSEIVHMVQDFYGDDRTAFIFTADHGMSDWGSHGDGHPDNTRTPLIAWGSGVARPMTTTDGSVASGHDEYSADWNLDHIQRHDVAQADVAALMTYLIGTEFPANSVGELPLSFLSANLKEKATAALVNTKGILEMYRVKEEQKNATEMRYRPFSGLDADAQLAPEQRVTAIQILIDAGKYEEAIEETAVLLKAGLDGLRYLQTYDWLFLRALITVGYLGWMAFALTIVLDLFVLHGATPPSRSLASSVFFSSILTTLYASFIMSKSPFTYYLYAFFPVMFWEEVVARRQSIVKSGEVLFSHISSGSSMIMFAIDTLLYVAVVESLAVGYIHREVLTVLFLVASLWPLSLGWNFIRAHLSLLLTWAFSCIVMSTFTLLPAMKTENVSLILAGGALMAFIGLLYLALEDYILADFSKPCHPQRQNMGSRVITGVQIGLVLLAMIVTHGSTLSLQAKQGLPRGNQIVGWITLVVSLLMPITYRLYPNSHYMHRLLSMFLTCAPTFIILTISYEGLFYVAFSLILVTWVRLEHRIDVEMTPIAINGVSGTKQNSSIEEDAKDTNHSLDTALVSVPVYRPLRLSDARVALFFFVLLQSAFFSTGNVASISSFSLDSVYRLIPIFDPFSQGALLVLKLMIPFALMSANLGVLNKQLRVAPSALFMLTMAVSDILTLYFFWVVKDEGSWLEIGSTISHFVIASLLCAFVAMLEGVSAMFISGMEVNEEEMTVMEKKKEVEEIPEQGMDTEDEKTESKKNISLLQEGTVEGEKVLKSKKSKGRMRTKIDKKKAINSSRGTDAEATAPEESQLKARPSISDALDSLPVASEPLLAEADVPIESLSDASLDALVKIIDEKEDKNMVGIEAGDVAETARTNAEPQLNSIGGGEEGPVAVVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLS6</accession>
    <name>A0ABR3ZLS6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000008">
        <property type="protein sequence ID" value="KAL1901152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018852">
        <property type="entry name" value="DUF2456"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28297">
        <property type="entry name" value="FUNGAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28297:SF1">
        <property type="entry name" value="FUNGAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10445">
        <property type="entry name" value="DUF2456"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="183" mass="20702" checksum="0C9999DF42E2A901" modified="2025-10-08" version="1">MYKHDYDNDAEKFVRLFAFPRTLAGDATLSVFIQTGTTWIIEAFLVQLDIHSGRVTPVAFFSEPKATLRRWFFALDSTKTENPSMRMSIWFHVSRILAIALPAWALLWGPSIGIMSTFGIKEPGTIDVYYESRWAGPLFKLVYASVLAVFTTPIMTSFWILRAAWAKQKGSVTLKLTPGISLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM09</accession>
    <name>A0ABR3ZM09_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Triacylglycerol lipase</fullName>
            <ecNumber evidence="8">3.1.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TGL3</name>
        <name evidence="8" type="ORF">Cpir12675_000256</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Probable lipid hydrolase.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.3" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021771">
        <property type="entry name" value="Triacylglycerol_lipase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF44">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11815">
        <property type="entry name" value="DUF3336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="7">
        <location>
            <begin position="198"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="555" mass="63249" checksum="C8715C24DE28EDE9" modified="2025-10-08" version="1">MGELKEASGYYFKWIREFVARIVGYDLFYLLYSSYTWVIYRLFWPSPLTQWRSLFTSAETYYNWQEAADNLNHLLDLDAWRFDARSRHYNRELIMGHIDAMDQTFVQPDGFIMSELFRSSLHRNLGNITTPALYKHCFGRTKFVIETFSGKMVTLLHLILQLPNQPPTGRQSAGRFMPSDMKMDFVVASRRALGCSSLLLEGGAMFGLCHLGVARALYQQNLLPRIITGVATGSLLAALIAVTSPQDLPALLNGHGIDLSALSGTDKWHHTWITRLFKLVSQMIRYCRKGYFWDVDALEKCALLNLGEITFAEAHDKSNIILNIIVPVPGDKGVPVLLNYLTAPNVLIWTAAVASNSASQSFTGGRRTIILCKDHNGQVMPWDHNEMDEHPHDRMRPLDIIARSFNVNHFVISQARPYVLPFIQSETDGPDLRGSNSKLVKLIKYLASIVGAEVHLRMEQLNTLGLLPTFARQLFLHVDVHHKPHMTIVPDVGVRDYIFLLDPPSKESVNYWIRKGEMAVWPLVCALRVRLQLEAELEKAYMMVRNELPENDTFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMA6</accession>
    <name>A0ABR3ZMA6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ADP-ribosylation factor GTPase-activating protein gcs1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">GCS1</name>
        <name evidence="8" type="ORF">Cpir12675_000419</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08830">
        <property type="entry name" value="ArfGap_ArfGap1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46395">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46395:SF1">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="7">
        <location>
            <begin position="14"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="139"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="190"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="304"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="350"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="380" mass="40445" checksum="644C292B6C6CB388" modified="2025-10-08" version="1">MASKAMWEVDPETRSKLATMQREPKNSVCCDCNAPSPQWASPKFGIFICLVCAGVHRGLGVHISFVRSISMDAFKAGELERMRLGGNAAWQDFFAAHPDTVAAGLTWDSATIAQRYSGDVGDEWKERLAAQVEGREYVPVPKKKKPAASPVSSASTSNAPLSGSRDPIATAGPGGKARVDDAYFARLGDANASRPDHLPPSQGGKYSGFGNTNTMPSSSSSNDPLPSINDLQADPVAALGKGFGWFTSTVTKTAKTVNDGYIQPTARQITESDQWKQAQVAAQTAAHQVARSATMGAKTAQDGFNRFVEGGNGSSTSRGAGGYRQAPIDDSKKDFWDSFSSIAEDRNAHTSIGTAAMGGASKKTHNSNISTKKKDDDWDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMG6</accession>
    <name>A0ABR3ZMG6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_000349</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1901659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="221" mass="24405" checksum="976CF31D8C6CC7CF" modified="2025-10-08" version="1">MTSSLVFEYFLFEFLEPAGSSLGYAPPESITTILHTIAAQPEIDNGAVYLGQYLESPSTWILILPWVSQNAYVEFKKSSRYAPIAGPLASKVQVLKFYMTSLSPDAYPALESKCTELLTTYGVDADYVDNGREFLDRMEAYGMDGYHGGAIGKTLDRIAQAEEETAQAACFVLGWESKEAHLDNKAKTGNPIIANLSLITRGAKALVMYHVNFTKYTKQTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMY6</accession>
    <name>A0ABR3ZMY6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mitotic spindle checkpoint component mad2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MAD2</name>
        <name evidence="9" type="ORF">Cpir12675_000164</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MAD2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.900.10">
        <property type="entry name" value="HORMA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003511">
        <property type="entry name" value="HORMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036570">
        <property type="entry name" value="HORMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045091">
        <property type="entry name" value="Mad2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11842">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11842:SF11">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02301">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56019">
        <property type="entry name" value="The spindle assembly checkpoint protein mad2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50815">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0498">Mitosis</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HORMA" evidence="8">
        <location>
            <begin position="38"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="134"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="147"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="248" mass="27588" checksum="C63DDC3EB2D33E5D" modified="2025-10-08" version="1">MEKTEKPEKPIKTKKSKSSSKDKDKDADGKKTHKLALKGSARMVTEFFQYSIHSILFQRGVYPAEDFTAVKKYGLNMLVSSDDQVKAYIKKIMSQLDKWMLGGKISKLVIVITDKDTGEHVERWQFDVQISNAKPSKSKSKGADENASASSATASAPSALELEKTEKEIQDEISALFRQITASVTFLPQLQGDCTFNVLVYADADSDVPVEWGDSDAKEIENAESVQLRGFSTSNHRVDTIVSYRYTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN05</accession>
    <name>A0ABR3ZN05_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Flavoprotein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000416</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HFCD (homooligomeric flavin containing Cys decarboxylase) superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="entry name" value="Flavin prenyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14359:SF21">
        <property type="entry name" value="FLAVOPROTEIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14359">
        <property type="entry name" value="HOMO-OLIGOMERIC FLAVIN CONTAINING CYS DECARBOXYLASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="Homo-oligomeric flavin-containing Cys decarboxylases, HFCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140860">
        <property type="entry name" value="Pseudo ankyrin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavoprotein" evidence="2">
        <location>
            <begin position="30"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="605" mass="69270" checksum="0F36E0B1986354DE" modified="2025-10-08" version="1">MADIPRRLMTASPATSSLSILEPTRPRNLHVLVASTGSRDTSWAQYLVLNLATSQNMAIRAVVDDPVLRLEQACTTWHNRSLAIPPPDLLKQLPTDPVQQGPNELEMCRKQACDLVDWADILVLAPLDADGISKMLAGFADTMLLRILRGWDTTKRILLVPGMSKQCISNHMTQRQLNEIHLNWPWVRTLPPIQWHYDPTSDCKRIVHWTGFNEVIHIIRNQAELFSLGCEVDLSLPSRLPDGGQRKSFIHLPPELWSMIMDFTGDWELAQALDIYTTIPEPDAWKCRPINISTPAGQMFGYELENTALRSTQAMVCHRLSQAPPDFTELTPLTIKLIIRFSMVTVLEYLEANRPDLFKAFDNLSFTMMASAYYGRTDVLDFWKRSPTFKGRHHLLYNSDVVDGASKNGFTRVLDWWWRHSGLPLLYTEAALEQASARGDIRVLTWWREVSMQDESIPPRPGKSLLTATQNNRLDVIRWWAESNIAVAHGDSIPRMASRWGKVEVLELWRQLQGDDKLIYDAEILTAPTTHQHIAVLEWWLRYARGELPGMEGRTHKVPYRTCTIEEALEDSIGDQNAVRNWWTKNGLNLGVRNFEWMTIKYLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNC8</accession>
    <name>A0ABR3ZNC8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH-ubiquinone reductase complex 1 MLRQ subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010530">
        <property type="entry name" value="B12D"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06522">
        <property type="entry name" value="B12D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="89" mass="9826" checksum="BE37D36051ACF9B6" modified="2025-10-08" version="1">MYATLGLRMMRQTPRLMRAAPVEDQAAHGVSARLRKLKNIPPELFPLGVVVAFAVGAAGYSLTRHLLTDKTLRLGRSSGDNKPHDNEHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ00</accession>
    <name>A0ABR3ZQ00_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UV-damaged DNA-binding protein rad7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RAD7</name>
        <name evidence="3" type="ORF">Cpir12675_000464</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056451">
        <property type="entry name" value="Znf_Tbcl_Rhp7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318:SF234">
        <property type="entry name" value="RNI-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23550">
        <property type="entry name" value="zf_Tbcl_Rhp7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA repair protein rhp7 treble clef" evidence="2">
        <location>
            <begin position="145"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="115"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="617" mass="68022" checksum="85736CB08621AF4D" modified="2025-10-08" version="1">MARRNGRRGITGPTSALSDFLAAHNISASEIRRTAEDRRRLIAQQCQQDDATVGPSDGAIVVPSDDEKDGDFVETSPQLGPRATRSATRRSARDSGKGKGKGKQAPKRKHSGFGSSDTSSESSDASESSDIIDALADLPRNRISQKEDCDVCSKQFTVTPYSKPGPNGGLLCMACSRKSKAATTSSARPRKIPATARKKQKDIMDRILVLGTKTLSLQCIELLVKNLHLAESVENLPESVVDRILRLVAKRRLLNSSTLSLFARPRSEFLYLYDAANLTMDDFIMCFNTCEILKKLAIHNGIQFKDPVMDHLIQTGAPIESFALHGGNLLSSASWMRFFKARGAHLKGIVVNYTDAAFNDEVVEYMVTHCPSLKHISIRHNPAVTSESLLSIRRLTQLTSLSVQTTKRIHVSDYVALISSIGSNLECLSLRSMTEMDDELLDAIHAKCRQLRKLRITECPSFTDAKMAEFFRSWDNLPLYHLDLDRCRAITNASEENGEIINPAIGPLAFKALVEHSASELRYLNVVSARHITTEAFETAFSVNGGFPWLTYIELSFCTQLTNELVEKLIAVSPCLQQVIVFGCLKLSARLKVPSHVKVIGLSNVQGMILGAQTIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YCJ0</accession>
    <name>A0ABR3YCJ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">U3 snoRNP protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">UTP18_2</name>
        <name evidence="9" type="ORF">Cpir12675_006916</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat UTP18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000422">
        <property type="protein sequence ID" value="KAL1886028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045161">
        <property type="entry name" value="Utp18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="WD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18359:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 18 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18359">
        <property type="entry name" value="WD-REPEAT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="556"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="183"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1886028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="584" mass="64423" checksum="0C0645AA228F9243" modified="2025-10-08" version="1">MSSKKYQEPDSGSESYFSDSAESDFGGFDQHSDDDSMNKDPSMFTKDAVEEELERLVLGNSSGFRRQLFDDLEASATAEAGMQLTTTSKNDDDIEELDDLDLFDLDFATTGEKKLGGAAAEGALDPAWEDSDDERMTVSLTSAARLRKFRVAGEDDTVNGSVYANRLRQSYLQLNPMPKWAQFGQAQAAKRRRRQSSDAEGSSDSEVDDEYGALPIDTFLRNAGQLGSANSTKRRKLRPEVLDIQRSRDIPDTHRGAVTSLSFHPHFPILLSSSPSSILFLHHIDPQAHPTPNPRLTSVQARQVDVRHSEFRYPAGDKVVFAGRRKYFHSWDLESGVVQKTTRVYGHREEHKSMELFKLSPCGRYMGIVASTRKGGGVINVVDTNTSNWLAAARLDSQHGIADFAWWSTGDGMTILGRDGQVGEFSMVDKRFLGLWRDEGCVGGIVLGLGGHQGPTELGEDGWVAIGSSSGITNIYNRGNLFTLNEEGDIVMTTRPTPTKVFEQLITPVTTISFSPDGQLIAFASREKRDALRLAHLPSCTVYRNWPTADTPLGRITAVSFSSDSKTLAVGNDSGKIRTWDIRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YDG7</accession>
    <name>A0ABR3YDG7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_006939</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000441">
        <property type="protein sequence ID" value="KAL1886005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47381">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47381:SF3">
        <property type="entry name" value="ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1886005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="343" mass="37907" checksum="2EE464E9B0916E00" modified="2025-10-08" version="1">MTSELPPVASASMRTITMAGLAVDVYGLEEISPSATRYSLLWLHHARTRDKSHMTDFANRMIAAWTALPESQGRAVICSAFDQRNHGTRLIDKRANKAWKDGNETHAQDMVGGIVGMVTDTISLIDVIEGYLFPEDMAKSGSRIDQHMILGKSLGGHTTWQALFKDPRITVGVAIVGCPDFMRLMKDRAQRTKLPTYDPSNDGVTFLGSKHFPPDLVAECRKYDPRGVLFGTTEIPDDIGSISDDEKKRITQTLVDKMGGKKVFVTFGGQDKLVPYSMSKPFLDFLSKATASWGGCEAVTLKQKVYEEAGHVFTEPMVLDSLEFLCDVMKEGPYKETEVESGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFI9</accession>
    <name>A0ABR3YFI9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_006710</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000358">
        <property type="protein sequence ID" value="KAL1887064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07216">
        <property type="entry name" value="Pat17_PNPLA8_PNPLA9_like3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185:SF4">
        <property type="entry name" value="SERINE HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G07870)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="4">
        <location>
            <begin position="19"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="137"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="467"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="612"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="2">
        <location>
            <begin position="23"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="150"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="548"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="617"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="667"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="676" mass="74267" checksum="823023F7CC88D680" modified="2025-10-08" version="1">MASSVRRRDTTKGPPLRILSLDGGGVRGYSMLIIIQDLMHRTFVESHGRAPRRHEIPKPADHFDLIVGTGTGGLIALMLGRLRLDLETCKELYASLTRMVFETDKTIAGIPFRSTIFKASKLEEAIRAAVKAHTVKISEGNDGSEPAPPSSSSDSTMGSIPPSRHASNASVVSFSARSQNVQPQIPYRSAMQRYGNASARLYDSRENRTKTAVTAVYKGASRGNSAAMLRSYDSRGGPAPEFDCKIWEAGRATCAIGIAFKPIQIGQSYFHDDGSGIFNPSAEALNEALVNEWPGRDVGIFVSVGTGKRPRSSIPKHQWYDGFLGEFAEVQRKMAAQIENCERIHERMIREHLPRCGVNIENYYRFNVEVGVGEFGMNEWNRLADISTSTRRYLSNETERKMLINTASKLAAIFRAVKRYRQNIDAAASNTRPVSKIGNDLLSPNLSPITPFDEAPPNVMELPAEVPDSWGALDSSPAPSQTSFESGADSGANFRINSRRSSADRTYTPAYSPSPPHSLAVPQSPVSSPHFSACHKDDPDRLVPLPLTPQNYRTNNGSDMIAIMSPDEEPMKKPSSGYNNQGPGPGHIPAYNQIRTTTISSDFENEGLIPLSTITSVPPPRPPKTPVPGYQLPPAFRPQSTLLGSRPHYTTLPYPDDSDDMSPPVVRMDRKPQYQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGZ4</accession>
    <name>A0ABR3YGZ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Calcium-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Cpir12675_006691</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the PAN1 actin cytoskeleton-regulatory complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Actin patch</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000353">
        <property type="protein sequence ID" value="KAL1887112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00052">
        <property type="entry name" value="EH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216:SF170">
        <property type="entry name" value="DYNAMIN ASSOCIATED PROTEIN 160, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216">
        <property type="entry name" value="EH DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12763">
        <property type="entry name" value="EH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00027">
        <property type="entry name" value="EH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50031">
        <property type="entry name" value="EH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="7 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EH" evidence="14">
        <location>
            <begin position="18"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="14">
        <location>
            <begin position="155"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="14">
        <location>
            <begin position="306"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="15">
        <location>
            <begin position="339"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="13">
        <location>
            <begin position="1256"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="258"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="376"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="554"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="722"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="810"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="902"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1004"/>
            <end position="1261"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="691"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="279"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="445"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="456"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="506"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="722"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="817"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="902"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="1012"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="1106"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1143"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="1174"/>
            <end position="1186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1212"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1238"/>
            <end position="1259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1887112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1297" mass="134309" checksum="9195F8AF64AAF540" modified="2025-10-08" version="1">MAAEADPSAPVLNLTPEEKRVFGQLFRKADHDNVGVVTGDVAVSFFEKTRLDSHILGEIWQLADKENRGFLTPPGFGVVLRLIGHAQAGREPSLELALKPGPLPRFDAIPTPAGLGSGSMPSPMIAPPPPVAAPLQAQHTATGGPVRIPPLTPDKVAQFGALFEAQPLQAGFLSGDQARQIFEKSGLPNEILGRIWQLADTEQRGSLNSTEFVIAMHLLSALKTGAMRGLPTVLPSGLFEAASGRQSPAPTGSGIGIPPLPTQMGANPPALRPAATGARPSTATIQSQSTGFGASMSNDWLVTPLEKQRFDQFYDDLDKTRRGYITGEEAVPFFSQSDLGEEALAQIWDLSDITATGTLTRDEFSVAMYLIRSQRSGRSGPLPSVLPPKLIPPSMRGPARPSTSASPFDAPMGSPVGMSSFAPPPVPTAPAASKSALDDLFVLDSSPASPKPAASTDVSSSSNDPFASTPTGIAKPSSPPPLFKPFIPSSSFGRGLTQNVTGESRGSGSPAPAPAPASASAANDLLGDNDPEMSSKLNNNSTELANLSNQISSLSTQMQNTQAQRSATQNELTQTNSQKQNFEQRLTQLRSVYEKEAQNLRGLEEQLRTARSETTKLQAECMSLDGTYQDLQNQKAQVTAGLQTDQQENAALKEKVRMLNSEIAQLKPQIEKLRLEARQQKGLVAINKKQLITNEGERDKLKAEAEELSKSIDDSRAALAERSTSSASVSVSASAARPQSPASSSAGNNPFFKRSASTDIKGVFSPASASPPSQAFGDSSFDDIFGVASSSAPLPGTAVSTPSPAIATAQQRENMGSSSASPSVSNSAFPPPAVVALSAPEKTTSPAPPGAFPFGEPASIAVAMTPRQTSPALSRAGGDAHIATSQATSAVVHNLATATSLSKSNSPAASSSPFAAPSFSSSPAPASVFLPPDSDVAATSTAAATVANAPTAETDNDPFSSMRANDDPDKAKADFDSAFASFKKSHSSGGDASSTETTKAFTTFKFNSEFPPVEEFDDDSDSSSDAGFDDDFAPSPPQPKPAADVTEPKASQEQPEKTASPFDMSTTPASKTDIFGASPFAAPSAPPTSLVPSQPPAAPSNKASFDDLDDDFEGLEDAKEGSADDDFASLSRSGIDDFGHAFDNTSSSAPSQTKSDSVALGGSGGSFDFVSRGSPPPASAVPPSGPVPLVGNGATTTTGHDWESIFSGPEGGAATAASADSGALGAIGVATFTPPPATVQSESQASGAPPASTQPSTGDQALDNLLMMGYPKEASLRALERYDYNLERAANFLATNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH39</accession>
    <name>A0ABR3YH39_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006613</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000334">
        <property type="protein sequence ID" value="KAL1887280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="489"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="498"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="525"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="605"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="672" mass="68944" checksum="0DF608264039881F" modified="2025-10-08" version="1">MRFSSIINVAVQISVAAAQITESMLAKSVDSMSLKSSFNPIKEAYWTGLPHHRRTPFAVSPDGKTGYIAYLDASETDVHVQALDPTTFKETGTAVTVTGAKEAGGLVAHNDGFALLTNEALPSGTSGAPPDNTPVAVLYRYDASGTQTWKTFLGGPNVDSDNNLASPDINGDLVFSEAAGYYAAYIVVTAYSGSATGHFGDAIRYITPDGKLENIPGASSSWGCSHNTGIALEAADAPPFASLCAEDQGALWLNTKSQGMMNDNVKVGNEHVINGASNEAMGGTSGSYSGMARFGGAKADSNSYVFTWVSRGAIDLTANTWMGDGYTKSKNRTVARNVAIATFSDKNTLVGEEATSVVGSADGDSQVNWMTDGSADCQNAHAATFDASNALVTWEQIDSPQCNFDAMGCQGAFSGTYYQQIGSDGKKVGEPLMSMDSFVAGDMVTMPDGRICWPYVAMDWKLDGPANAMQASASKMSFACIGLSGGGGSGGSGGGSATGSSTAPASSAAPSTASSAAPNGATPTEYTAPTENNAPIENNAPIENSIPTEAAAPTNYEPSGPEAPTAPPSTFETVVMPSAAPTDAPEGIPVNPGPGEDYPVDDTPAETATSNSAANTTPAPYPDFSGFPDLPSLTSMPGGYGGYGGYGGYGGFGKGKECNIKGRTVTVTTTVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH41</accession>
    <name>A0ABR3YH41_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nuclear GTP-binding protein nug1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">NUG1</name>
        <name evidence="7" type="ORF">Cpir12675_006664</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000345">
        <property type="protein sequence ID" value="KAL1887167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04178">
        <property type="entry name" value="Nucleostemin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014813">
        <property type="entry name" value="Gnl3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050755">
        <property type="entry name" value="TRAFAC_YlqF/YawG_RiboMat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089">
        <property type="entry name" value="GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089:SF30">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08701">
        <property type="entry name" value="GN3L_Grn1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CP-type G" evidence="6">
        <location>
            <begin position="185"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="88"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="91"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="104"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1887167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="548" mass="59332" checksum="86AB66D2EB1A8654" modified="2025-10-08" version="1">MAGNINKPKKPSSKRSTTRLRANIKKASNSKQRKDRKLAKKNPQWKSKLKKDPGIPNLFPYKERILQEIEETRIQKANELQRRKKAAKAAKAGEIKGTKTGDSETQEGNDEIGDMAMDEDDEDDEDFNDEEVDSSNPMAALLASARRAAEDYERQLAASDDGMSDEEASDIEIGSDQAASRRAYDKVFKDVVDQADVVLYVLDARDPEGTRSRDVEHSVMAAANGGKRLILILNKVDLVPPKALRDWLAHLRRFFPTLPLRASIPAPNAQTFTHKDMTVQSTSAALFRALKSYAASHKLKRAVSVGVIGYPNVGKSSVINALLARMGGKAGLKTRACPAGAEAGVTTAIRQVKIDSKLTLLDSPGIIFPSTGRSTSNAGSLVSMAAATQAHAQLVLLNAVPPKQIDDPVPAVTLLLQRLSEQSALLEKLLDVYDIPPLVGSGGDLTTDFLVQVARKRGRLSRGGVPNLKSAAMTVITDWRDGRIQGWAEAPVLAVEGVTEASASVSKKADEPAADQKHIVTEWAAEFKIDGLWGDDSAAAETDDVMQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJE1</accession>
    <name>A0ABR3YJE1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006198</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000264">
        <property type="protein sequence ID" value="KAL1888361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019431">
        <property type="entry name" value="DUF2417"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10329">
        <property type="entry name" value="DUF2417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="551" mass="60363" checksum="C410C823B79BC987" modified="2025-10-08" version="1">MPAGSYHRPTGSTDSGLGIEAGDGVHNINEQTRLLSPVPAEEIHSRWLSPDDPAVTPYNLWSVRVLRLLTMAVAGITSVWFFVLLVSMFATPPGISTRGSVFYSLFYTILSLTMLTTVLLFFDAPAKSSRILSVVIAALLVVNVVLVLAVEKTRIEEGWVGVASALWALLVSLWILLVDITVKWGKAEEEERLTGRAENRRTALEWLQVVLSNLTLTFALVVLISTTLNLTLRSFDAALGPPGRQVWVDGGKYRIHVYCADATTGDFNYATPGSSSMWMPPAPVVGPRKNVNKDKPTLLIFGGETSAENGMWQVAQNALHNGSIDRYCLVDRPGYAWSDAAPSPLSASMAVASMSEALSLMGEHGPWVVTGAGTGSFYARIFAQQQGREAVAGILLIDAVHEQQLYQLGSAGRGFGLFLRGLVSPLGLVRLPGAVLRGRSRADRVWGRTAAQSGKTAFAMLQENLVAGSLTQREVLATRTLLREWDIRLGVVSSGDMVRHDARWETWQRDLAMLTRNLVGWDTVKGAPHQIWKTEKGRWALEDMMRRMVHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK44</accession>
    <name>A0ABR3YK44_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Calcium channel YVC1-like C-terminal transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_006234</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000269">
        <property type="protein sequence ID" value="KAL1888252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052971">
        <property type="entry name" value="TRP_calcium_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056336">
        <property type="entry name" value="YVC1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35859:SF5">
        <property type="entry name" value="ION TRANSPORT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35859">
        <property type="entry name" value="NONSELECTIVE CATION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23317">
        <property type="entry name" value="YVC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="314"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="376"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="449"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="507"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium channel YVC1-like C-terminal transmembrane" evidence="4">
        <location>
            <begin position="320"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="142"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="635"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="673"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="152"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="191"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1888252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="710" mass="79431" checksum="56604BEBB5844DF8" modified="2025-10-08" version="1">MPIKVKMRRPRELSPTPPPIASSPGQLPDIDDDDTFHVVIKKLSRYLNETIHVPSSFEQLRTTVAGDCVQSLVEHLSVVCHNRCIVNALLALKWHYDAQDEDRGVSLSRGYVCEIVAWRFLARLSVKETVDFCLHEIDEEDQDHYDNSDTQSDSDNDDASEETQVQHLALGHHDEEANEVSPLLSQSQHYGSVSSRRGGAVSTRPGSSSKRYELVGALSRLTMSSTHMGDDHGGPFQDPTGPFRGLNALEIAAISNSKRFLSHSVVQKLINGIWNGDIIFWDSLDVNATKMPRFYNPSQNDPFSRLRVPKYAKAWEVFFFLTFLCLYYAVMMERNPTSISGKEALLYVWIASFFYDEISAWIDAGSIFYTSDVWNMFDMVMIFIALVFIAVRSLGLYYHDAKIIEFSFDILAIEALFMVPRICSILSLSPYWGSLIPCIREMARDFCKFMVLVVIVYLGFLTTFSLIAREVYTLPHMTMMLTKIFFGNTGVGFDAMDKIDPVFGPPLMFTFIILSNFLLMGSLTGMLSNSFSRIITHANEEYLYVYSIYVLEASTSNRLTHFLPPFNLIALVIFRPIRLFLKSDSRFRAARIVLLKATHWPVVCIIKVYEALFGDGTSVSFSGLKGPVPTRGLSIKNKPSAHLGPPTSSGLQAPPPTTAVTQSSTHALAAQSNAALEAKVIDLAAKIDQLMDLVQAMQEQQLSSSPSGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK77</accession>
    <name>A0ABR3YK77_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006197</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000264">
        <property type="protein sequence ID" value="KAL1888360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="179" mass="20572" checksum="FCB3D7C57E34F441" modified="2025-10-08" version="1">MRSSSYRPDDVSTSLRSLWEEAMTLPQRTLSVKQPSGVLPRRSYRQHQKTHSSFSMPRRHATDATKYQQHTRSTSTMSRSITMEYLPRHAPPPTPLSLNPMPCQVRDKTGQFHVVPDTMSHFEILAQPHAQVLPQLDGRNSPLLADDKSSAETAHSRSERFSLRLRKWLSLRGRSPMRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKB9</accession>
    <name>A0ABR3YKB9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000251">
        <property type="protein sequence ID" value="KAL1888662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046486">
        <property type="entry name" value="DUF6579"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20219">
        <property type="entry name" value="DUF6579"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="340"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="386" mass="43477" checksum="A5D5F685C088D16A" modified="2025-10-08" version="1">MASAALWQIIADKRVRRQAWETAVRLSDSPLVKCIQAGDTVGTVRETIREINRFVPSMQVVGKSMCDSAHLFGYFNAAAMAAQVGSNMVLTYQGMQALQLIAEKLEGISTTLAAQTALMAQKDFPQYVHAMLRERIGQTSADPHTSHWFFVFHPDNDWYPPFYQLLEKEPLGPSFCGYTNQIDTCFLFMLAARRLAEKRDRHARRRRHTPVPVRIHLLIPAYQPILVAEPLHIPDEIGDFVMEGRIHNNKNFVWFNLPDEQRHYCDGIGMWQPPSPGFFMWAFGRLGLVSTGPELGERRVIGTSQDGVKKARVDEKEIGDEEPEEDISSVAATAGDLIETGSSTSSNGRGNNRKRIEGAKKTAMPLHQRQSQKEPSRRSSRRTGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLW4</accession>
    <name>A0ABR3YLW4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mitosis inhibitor protein kinase swe1</fullName>
            <ecNumber evidence="8">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SWE1</name>
        <name evidence="8" type="ORF">Cpir12675_005847</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000222">
        <property type="protein sequence ID" value="KAL1889298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF196">
        <property type="entry name" value="MITOSIS INHIBITOR PROTEIN KINASE SWE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="778"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="327"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="391"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="469"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="524"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="601"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="707"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1035"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="136"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="483"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="559"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="605"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="616"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="639"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="720"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="741"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1035"/>
            <end position="1054"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1155" mass="124905" checksum="577CF20375F88CD4" modified="2025-10-08" version="1">MSFTNGGGTLTLPSPTHPAHVDMSSAVRSLRRSLSRSPSKFNSPTSQATIDSSGNSVSASPQSPCRRYTPALSTPETPSLDSAPVTDPSTNTTRFNPHSSTTPADSPTRKINRSPTRLFPLSSSVNFQPDAFDSTPLRNSLKISLRSTRSNRGLKASPSRVISKPRGSPKSAFPPRRALGLSESSQSGNLVLPTFAGFDASGQENAPATAPGSPLNATHNANKITRHSLHLDVTGNSSNLLKTLHPGVDLIPGLSIGQKRSDQMDIDSGNAGSPVAKRRSLHGIATSSPINSITATDNVFGGSSTPTKTSSFDIHEEAGKANYELSSLAMPPPREPITSSPNPTARQRSSLRRTTLRERTSWGRRAGAQQLSQMGGEFATPISRTRPRLSMDQFVPPQDSQFSPNVMLPPSTISDRPQRHPLSRSLKPSESGGHLLDGSPTTFPEPFVPPKAKIPGLSFSKSVPYGLPNPMAPPPNPISMTPGSQSQSRQTPIMATPNQNPLRAKPRSFMSTSLISKVNRNPEDDRKIVVPDTPCKKQNHGFATYPPPPGSALKKSGRLSFSTEPGTPLSTDSLFGESASINFGTPNPRGLGLFQRLSRHSRRGSVLDRDIEDKQSSTPYKTGTSTPENDVAGLDIELPPTPSRQPTSPPTNPSPQDSPSANRYSNPFSATRRFTRQVSSEVSGDVVGSPLTRRKNRLTALKLSSPSAGFLDVPRTPRESSLGPDGGRLSLSRSSANLNSETPATPTTGMRSHRVVTPVNPGQRLNRMELDDDLAKRFGRVDPIGTGEFSTVYRVAYPKEASTTPVGTPDFRSSLFRSTPRPPPPGSAFAVKKTRHPYHGTRDREIKLREARILAQLTHTSHIVRYIDSWEVEGHLYIQSEYCDNGTLDKFLASIGRQGRLDDFRIWKVLHDLTLGLQEIHTAGFIHLDLKPANIFITHDGVIKIGDFGLAAAWPVEKSINSEGDREYIGPEILEGKFDKPADVFSLGIIMIEMACNVVLPENGPTWVALRSGDLSDVPSLTFGSVNDLSQTSSAADLNSLDPSPSRHSVTSSDGEPIATGLPDFGATVFPALEEPPSFMANEEDVFSLDYLVTAMINPNPASRPTVEQILSWEAMRWVVARRRMPATIYEGRWGPSLDTPAKLCQAEDTEMMDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNB3</accession>
    <name>A0ABR3YNB3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PRE6</name>
        <name evidence="6" type="ORF">Cpir12675_005619</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000202">
        <property type="protein sequence ID" value="KAL1889851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03755">
        <property type="entry name" value="proteasome_alpha_type_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="1 2 3" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="5">
        <location>
            <begin position="5"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="240"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1889851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="267" mass="29186" checksum="E80970CA73621DBA" modified="2025-10-08" version="1">MASSYDRALSVFSPDGHVFQVEYASEAVKRGTCAVGVKGKDVVVLGCEKRSAMKLQDTRITPSKLGLLDNHVCLAFAGLNADARILVDKARIEAQSHRLTVEDPVTIEYITKYVAGVQQRYTQSGGVRPFGISTLIVGFDKGSEIPRLYQTEPSGIYSAWKANAIGRSSKTVREFLERNYKDDMDRDATVRLAIKSLLEVVQTGAKNIEIALMAPGKGIEMMPLEEIEAFVKSIEEEKQEEAAKKKTGRTPGTGTATILTRGPDDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNI5</accession>
    <name>A0ABR3YNI5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pre-rRNA processing</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">LDB17</name>
        <name evidence="3" type="ORF">Cpir12675_005594</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000200">
        <property type="protein sequence ID" value="KAL1889926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030125">
        <property type="entry name" value="SPIN90/Ldb17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018556">
        <property type="entry name" value="SPIN90/Ldb17_LRD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13357:SF1">
        <property type="entry name" value="NCK-INTERACTING PROTEIN WITH SH3 DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13357">
        <property type="entry name" value="SH3 ADAPTER PROTEIN SPIN90 NCK INTERACTING PROTEIN WITH SH3 DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09431">
        <property type="entry name" value="SPIN90_LRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SPIN90/Ldb17 leucine-rich" evidence="2">
        <location>
            <begin position="182"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="506"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="590"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="508"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="534"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="605"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="619"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="653" mass="71806" checksum="044A9D5832AFE390" modified="2025-10-08" version="1">MATFDRLESEDQFWQALDDCLTKRCRTNELIDHTLRTWLYLVAAVRDALLHSEDDVANCAHKLMGSLVFDENKDYVRQQLISNLLQEDECAPLHVVAWFMLLDGRLNPDLFRLMIQNASFPRLTELISRHGRGHGDVRLHRLLLELMFEMSRIERLRREDLVRIDDAFVAHLLQAIDSVSDDAHDNPTIKVLLVLNEQYMLASTSVANVSSTQETPPEAPLTNRVIKLLSLEGSSYRNFGENIIMLLNREAETSYQLLILKVLYLLFTNRTTYEYFYTNDLKVLVDIILRNLMDLPEDKASLRHTYLRVLYPLLAHTQLNQPHSHYKRKDILAILSLVAGQAGSINAHFAPTDETTLRLVERVRNVEWLRDAVPASGGESRWELGQYEKANSLLEPETDGSQENLALNKASDARKMDKGLAQRLLGMSLSPSETSSMVSVSDVAAVQEKPGVTTPSRIAVLGGELPNVDIDGVVAGELPTGVISNSGTPSRANSLTPAEAPVIAIQNASPSPTPSGAASITSRTSSLGSIVPGRLKKPRPQVPKHRHGVLIGHHTKHGGGHHSTTTASATTIPSKTATAEEAAAVSANQIPTSHELGIPNDAGEVSSVTSSASTTGKAMPKRIPPKAPPPRRQRLSKPSIDSLALAAQQSFKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPR2</accession>
    <name>A0ABR3YPR2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MutS protein homolog 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">MSH3</name>
        <name evidence="10" type="ORF">Cpir12675_005600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutS family. MSH3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000200">
        <property type="protein sequence ID" value="KAL1889932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="entry name" value="MutS, connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003810">
        <property type="entry name" value="PRK05399.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF122">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55271">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="9">
        <location>
            <begin position="1008"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="196"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="14"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="208"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1889932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1169" mass="128403" checksum="B90C6B2A2E1D6570" modified="2025-10-08" version="1">MAPTPSKSSKQRASKQQSLTSFFSPKSSSNANAQSAPSSQDAPTTSNIPSSPCLPVRKRHRSDISHNGNGSPDKPVKKPKKTGGSSATARTITDDDDDDKKNENKDAQTIRPDPLPEAENALLPTPAGTCSGAEAPPSLGPRPEYFASDSNHDVYLNSMTPKECEERIARHEKYVKKLGNPNSTVALGRGRGWGWRSLETPENNGGIEGEDEEEAEEEDEHPGKKGAAKKGPASKKLTPMLQQYLDIKRKHMDAILLVEVGYRFQFFGEDARTASKTLGLMCISGRLRYDDDPSEAHIDRNKFAKASIPVFRVNVHLKRLINAGYKVGLVRQVETAALKKSGDNRNAPFERKLTNLYTKGTCVEDIDEDDVRSSSTTNFGGTAGGYLLCLFETPVKGSLGADEKANVGMIAVQPSTGDIIYDAFEDSFMRSEIETRLLHISPCEFLLVGHMTKATEKLLQHLSGTDSNVFGDQTRIERVSTDSKPETLVSTASSHVTQFYADKAQANSTDGTLQNLLNAVLRLPPPIKVCLSAMITHLTEYGLEHVFDLTKNFTPFSQRTHMLLNGTTLESLEIYRNATDNKEQGSLMWALDKTMTRFGRRLLRKWIGRPLLDYEALIERTDAVEELFKSRGLPHLVQLESLLFATRIDLERSLIRLYYGKCKPKELLTLLQTLQRISMEYESIASPEQTGYTSPLLRKAVLSFSEIRDSVTMFLDKINLKAALEDDMLNFLREEEHTNRMQEHQCGIVSVEAGLAEQKDSIAGALRSKSPINFVTVSGIEYLVEVANSEVSRVPASWIKISGTKKVARFHTPQVIRLISERDRHKEALAAACNDAYKDLLVEIATFYQIYRDVVTSLASLDCLLSLSKVAAQSGYVRATLLPPSDSPSVHIQNGCHPIAHHTLPTGYIPFNTALGAISPPSSAEPVLTHLITGPNMGGKSSFVRAVALLIILAQIGSFVPATSATLTLLDSIYTRMGARDNLFAGESTFMVEMSETASILRAAGPRSLVILDELGRGTSTHDGAALAQAVLHHVATTTRCLTLFITHYQNLARVADALSPAVKNVHMRFAAHTNADGEEEITFLYEVAEGMAHRSYGLNVARLARVPQRVLAVAQTKSTELETDIRKRHLAAAARALVALVNSPGGDEYANSEEDNALNYLVRSIEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ45</accession>
    <name>A0ABR3YQ45_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000194">
        <property type="protein sequence ID" value="KAL1890105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="802"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="208"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="268"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="315"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="496"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="594"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="642"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="669"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="739"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="804"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="831"/>
            <end position="842"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="842" mass="90740" checksum="D66335BAC2B32EE0" modified="2025-10-08" version="1">MASFPIPSQDGAYPRMPGQQHKPVSMSQVQGFGFETDLEKQQREQRERREQWKLRNLREEQQHQQERQEKPQAHPQVHPSHAHQLQQKQLPRPPQQLSQQQQQKPLSHSHSQQQLGQQPQQKPLLQKQLPHQPQQQQQQKQQTPLPHSHSQQQLAKQPQQKQVHLPQKQLPQQPQQLPPPHPNSHSHPHPPPRQATLNRKPSMNPLISPSAHQQSQSQPQQTQSQPQYPSKPAQPPYLPASPSVPSALQSSRSQPKFYPGHYGQQNLPGQPTSFPQQQQQIHPPLSPVYGQPAISNPTSYHQPPTVPHSYSAYGSAPVSPSFASPSSHQFREPTLPHLLPPKKPVASQRTTRPDIPELQSGDVPSANPSIQKLRSDVPLNTAPSAFVAELDSGMAMADFIAEMPGNEPHRLNEGPDGSGSGKESPSVGQEQGQDAAPLMQANPWGFFLEDNPVIDPQRRPSQDGSKPVDDGVFEADSTPVKHDSDPGPVELADSTLPVSTNPGSATTTTTQGLPPKSSTQSRPEPRKDTGPAYESIETPHALASSSAKSPGKFIPFRPGVSPTLSAGLPSASPGLPQPSPPHSAQNAPIPPRRPSLASPPASAVSTHPPPPPERIAPINQQHQGLKYRPSMPNMHIGTPSSPGLPPPLPSPARIPSPTYANTFPSSQNPSPPPLPPPPPYTPMESPPSTNQPATPALPPRPSTSHNNSAPAFGFGHPNMAQYPPPPHHPSLANKPQHLSSSSTASSSSAPSPASSCPFTAGRQPRTAIGEASMKLLNSKAVKMLASKASNIIETRMSPILGTSADGQARSTQPPQQTGVLHGVGAGLRTGRSASHSYSQSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR49</accession>
    <name>A0ABR3YR49_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">D-lactate ferricytochrome c oxidoreductase</fullName>
            <ecNumber evidence="7">1.1.99.40</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">DLD2</name>
        <name evidence="7" type="ORF">Cpir12675_005617</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-binding oxidoreductase/transferase type 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.99.40" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000202">
        <property type="protein sequence ID" value="KAL1889849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="entry name" value="Vanillyl-alcohol Oxidase, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-bd_oxidored_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051264">
        <property type="entry name" value="FAD-oxidored/transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43716">
        <property type="entry name" value="D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43716:SF1">
        <property type="entry name" value="D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="121"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="552" mass="60179" checksum="4EE5B065CE0F4669" modified="2025-10-08" version="1">MASRSKISPLLRACICRSSAPSSTTPILTHAVASHLRIGGIATATVSQRLLSTSARLRAPEISLTADKYTDITRGDFGTLTAEHVAHFKSLLGNESAVIDGVTTDASGDIAPFNEDWMRKYRGQSRLVLRPKTTEELSQALCYCNEHKLAVVPQGGNTGLVGGSVPVFDEIVISMSRMNQVISFDDVSGVLVVEAGAILEVTDQYLAERGYLFPLDLGAKGSCQIGGNVSTNAGGLRLLRYGSLHGSVLGVEAVLPDGRIMDDLCTLRKNNTGYDLKQLFIGAEGTIGAITKIAIQCPQRPKAVNVAFFGLESFEQVQRAFREAKGQLGEILSAFELMDSESQRMVSVAKGANRPMEDYPFYCLIETSGSNSEHDYEKLEKFLEDVMEKEIVVDGVVAQDQTQITSLWGWREGIAEALGHWGAVYKYDVSIPLGEMYQLVEDVRVRMAEAGLVGTGDGDLVVGIVGYGHMGDSNLHLNIAAHKYDEKIEQVLEPFVYEWISKRGGSISAEHGLGVAKKKFIGYSRNETVLGMMKDIKKLYDPNGIMNPYKYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS30</accession>
    <name>A0ABR3YS30_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_005300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000177">
        <property type="protein sequence ID" value="KAL1890668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1890668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="406" mass="45309" checksum="F96219B0816A2846" modified="2025-10-08" version="1">MVQPPSKSSCLYFSHGVRFQPKNTGRPYENLDGSRRVIIDNLPSDTHLSRIMERIWGGRVVSAVLLDMPVIVSKTTKRFDRTEAVRKCAVIEFARPECAITFARQASSTHPIGAYTVPVVFGNCSLPTAISSTSMSSTRCQQRESTFSADIVRTKSYPMSVATRSYIKQGFSRYIQATNFNPAFIMPFLLDAGMHHPEAAEQLLHISLDGQQTLHLYFSTLKRAVLVYGVLTTAPKYGYGRPDDPNTNAYTSLYVATLPSHAALRDGDGTPKKPTLIWGRDPCDRVAIVEKGRRFSPVTQDPSYFHFMQRFHETISRIEHLPLPFSLSALEPGWVNSPSPVLAPIKVATPNVALIQCPPTKAQAMRQSLDQASPLGTSFRKIIRRQGLRGWEVTEADHWKELESLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS46</accession>
    <name>A0ABR3YS46_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">SNF1-interacting protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SIP3_1</name>
        <name evidence="9" type="ORF">Cpir12675_005071</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000161">
        <property type="protein sequence ID" value="KAL1891136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07609">
        <property type="entry name" value="BAR_SIP3_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13280">
        <property type="entry name" value="PH_SIP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039463">
        <property type="entry name" value="Sip3/Lam1_BAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042067">
        <property type="entry name" value="Sip3_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031968">
        <property type="entry name" value="VASt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14248">
        <property type="entry name" value="CYCLIN Y, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16746">
        <property type="entry name" value="BAR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16016">
        <property type="entry name" value="VASt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51778">
        <property type="entry name" value="VAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="PH" evidence="7">
        <location>
            <begin position="332"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="VASt" evidence="8">
        <location>
            <begin position="1006"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="976"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1223"/>
            <end position="1257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1483"/>
            <end position="1508"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="68"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="980"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1236"/>
            <end position="1247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1498"/>
            <end position="1508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1548" mass="169938" checksum="FBB314879CDEC106" modified="2025-10-08" version="1">MSTPLPPPAFNAPPTPGMPLTPSTCTHDSMARGRPIPVTLTEAGLDSPTFRACAAYYADQIEAVERWLESATKSASKLTQEILSLEDTINLYLNKLTPPMAIADNMLDQDYTLLALKRVSDASREWWMQVLSMMRKMNATMVDPVRQYINGDLRAFKEARRTLDTTQRTFDQALARYASQNKTKEPSFLREEAFAVHETRKAYLKACMDFCVLGPQARASLDKLMVRQCFELAREVKLSRDIAHNSLPWTEDLDRIRGWSKEMEAAEPSFRRELASIRREISDAAILAYQPSRELEAYSASTVPFLGSRGPVSSLQTAVKPPAGSPGGLSSVLERQGWLFLKSVSGKPARTQWVRRWFYCRNGVFGSLQHNSQGVFQDDEVGVLLCSAKPAISEERRFCFEVKTKISALVLQAETQQQLSEWLHVFEAAKKQALETSTSKEFIPMRTGSDPAFSIKPPSAPEFSTRNIDAAMATALALDDSALAVPSLEPALSSRASIDVYGNQAPRRSFTAAIGRDSDDNHSHSSNRIMSRRDLHRKATLYNMDPPQSAGHGPVGGIAGLTSVSTPSSSKGFVAAVAAAAMGQIDMPPGSLAPLTPPRPPLGTNMTRAAIQAATDRSVDMGTPYQLPAFLLANFWGSNAWSSFYANGQLDYKKEEERTLALAASEGKNVTAAYPPPGASHRKTMSADMIQPTLMSEKLDLQTAIPKRPQYPIVPKSHSQEAFPPKYPPELKVQHASFRLLFPSVPMSEKLVLVFRGAWSSTRGSGPDSDAGDTKLTATGRVFVTPDSLHFYGTRMGLLVAFSLSLDWVSEITAAPGKDCDYLFLHLTGAGNCQSQSNDVANDGRQKTKSPSDIGLSRITIKTFLENLPLLQARLNVLMDNLQAEEPMDIQDITTTFIDMERGHDSRIPDSPGGSVSVGSWEEIEQPPFAPITLSLPPAAAARTENQIMELQSQKAHAPPPVSPGLPRIAMGARRSTGLSTGGRTRGNTGGRLLPRGPSGYEPDDMKTKVCERHFEIGAKACFHVVFGDRSYIFARFYNERQASNIEQRPWALSEEGGRMRREFRYRADTADMLGRTRPENITDYQIIDMFADHATYVVSHVNTAWHLPFSSHFRVVTKMVITHEAKSRCKMAFYTRVDWGSTAPPLGKRMVDKQAMNDATAVIDALADAITDQVHKLGAQSRTKKAIQVYGHIGGTTQTVVYAGDGGADNVTVTLAKGGMGADNGGESATGTQLSSGSKSKDSNGSANGGGGIRINGISSSRATTLRRHTLTQMAFDTLFSFAESIATSVLMSVFAVIRSLFRLISAHRVLLGLLVASAMFNVLMTSKDASTWWTERRAARFMQRVGVGPNVVMSRAVRWEDLGAAVGSSEPLWNTGSECYAAFQAITNSTDPDVHLDSPASIASSSSFLTTPHSYETARRMHRTRQRLGSYRHDLLVAMRVINKIEREMEVAEWESWVTDENQRCAQLRYALDVSVPAVQKSNEGGLETETDTETQEGRGDTHGADKLAERRKALFHWYKDYCGSCTADALKLAHSQEQQQQPNEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT14</accession>
    <name>A0ABR3YT14_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005155</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000165">
        <property type="protein sequence ID" value="KAL1890998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39610:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39610">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="62"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="180"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="318"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="290"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="29"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="62"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="201"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="318"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="332"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="368"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="425" mass="44754" checksum="7F504A15BA3124CC" modified="2025-10-08" version="1">MPDLNSLPPSPRYPQESQVAAQAHAHLPASTTASGSPATMTSPSAQHVVPSALNILPSNQAAVISPPTSAPSQQVSGPPPGRQSLSSRTSWQSLHGGNTDLNTSGLIPIRHPRPMTAAQLHNELEQENEAVVNRLTRELSLLRAAQNASVISNTSSTSAHGDCIVDQHAHPLTSPVYPIPISPAASRRHHRAASNASMRSQTAGSISTSYEARRSSAIPLSRQGSSASRRSRTDSPGPHSIALADSTLAYLQQQRNPLPTSVPPMMGATGSLPDQVSPALLPVTPRYEETALYRAELEAAKRENDALKRRIRELERMVRNRRPSDASRQRSESVSTTASINPTIGSGIGVAPPREPIHIHTHPSHHGQPPSTSTSATPASALSQPLPSSPRPAPVRQTSASGSIAVGVPEEEVKVGESATNAGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUW1</accession>
    <name>A0ABR3YUW1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_004632</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000136">
        <property type="protein sequence ID" value="KAL1892164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018908">
        <property type="entry name" value="TMEM234"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28668">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28668:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10639">
        <property type="entry name" value="TMEM234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1892164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="153" mass="17150" checksum="A81DA02665F0A9AC" modified="2025-10-08" version="1">MSESSAETRPPVVNYVLSFILVGIAWGFTTPFIRRAAKTHNPPVHPILTSHAVRSSWIKSKVYGAFFAAIDLLRNPRYAAPLVMNLTGSVWFFLLIGQAELSLTVPIVNTFAFLFTILGEWWVENKVISTRESLALACFEEDKVSTIRVIGMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV66</accession>
    <name>A0ABR3YV66_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_004850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000147">
        <property type="protein sequence ID" value="KAL1891777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1891777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="75" mass="8440" checksum="A7730767CFC4640F" modified="2025-10-08" version="1">MKRSSQNPSYTVSPIDRSEVKFVLPGSRQAAHNMTIVTHMNLIQTAQPFLEPAILEDKWREAQEAKNKNAKSASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWA9</accession>
    <name>A0ABR3YWA9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adenosine deaminase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_004650</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000136">
        <property type="protein sequence ID" value="KAL1892182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409">
        <property type="entry name" value="ADENOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409:SF39">
        <property type="entry name" value="ADENOSINE DEAMINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Adenosine deaminase" evidence="4">
        <location>
            <begin position="232"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1892182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="578" mass="66154" checksum="002C597B9F80AB20" modified="2025-10-08" version="1">MVTPYTDDEWSEIKDELPRTEDPFMVQYLKGREALIQQEQKQRSDAAFRAALSPIGLKACAIVDRIRAAEQTTIWTPTKEDALAQSERLPYYPGMMFTHAKARMEETKLWNIIRRLPKGALLHAHLDATVDFDYLFEALLGLPGMHMATDHPGLNSASSRENAALHFRWRKTSDLSGSEIWGSEYTPNQFVPLVQAADSYPHGGRDGFTRWLKTRCTISTTDSEEQFRGVDHIWTKFANCFMVAGQILHYEPMTRIFMQKLLSQLHEDGVSWAEFRYVWPRQYYRDKSETPETDHTCFLQTIDEEVAKFKVANPSFWGIRLISTTVRSFDSRSITHAMEQCIIQKLAFPHLIAGFDLVGPEDRGRTLKDLLPELFWFRKQCALEGLEIPFFFHAGETLGDGNDTDKNIFDAILLGTRRIGHGFSLYKHPLLTQMVRDKRILIESCPISNEVLRLCGSIMSHPLPALLAQGIACSLCNDDPAMLGQEHAGMSHDFWQAVQGWDNLGLAGLGSLAENSVRWSVFEDQNNEEWIADIKEASFGKGEKSRRLKEWRVKWEEFCLWVVTKYGDEENEESGKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWM9</accession>
    <name>A0ABR3YWM9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000123">
        <property type="protein sequence ID" value="KAL1892794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="266"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="292" mass="32861" checksum="EB35561568C1E616" modified="2025-10-08" version="1">MSPSPAVTRQGVRDSKSDTHNEDPTVNGMSLYKQEALRQSVTYSSESHDFFPILMSIWSENFLPPITTTSIKSCINSLRSQAQLTNTTFAFAESLTVPEHLLTSVTFAWKMAVQSSAPKFYSDGASPCSITASIAKATSDDALSIARNVSLMFRSFRYQPKTSLKPLIGQVEKIRFIQRDIVGKFHERPFTWAVDKLILEYHSCITLIPNLEDTTEWEAFSSLLHTKQTFKESQINLRFCRTYQTTQKYGEHTNKRDSKLHGAMATTSCTSPSPSTQAHKYPSSPPKTILFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWP3</accession>
    <name>A0ABR3YWP3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">UBP2</name>
        <name evidence="8" type="ORF">Cpir12675_004392</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000122">
        <property type="protein sequence ID" value="KAL1892809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044635">
        <property type="entry name" value="UBP14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025305">
        <property type="entry name" value="UCH_repeat_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982:SF6">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13446">
        <property type="entry name" value="RPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="7">
        <location>
            <begin position="557"/>
            <end position="1151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1892809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1184" mass="133802" checksum="53E0EA257937007F" modified="2025-10-08" version="1">MSLNLDGLPGQVQETTNGDLPLPYARSAPLLIHDLLDQNLGPEWPEFMNLDTDNTIWAKTYGSHDLSEHLVAPGGRKRLQTKHTLLQSGVQNGQLDGETFFNSSCCLHCCHHFLVRITKPSGEQSPCKCPGKTLSEGFHHLTFWSTYTNEEIREITTERRRLVTGARYRCTADNCGVVVEIEISQPRISAEWIQKLTDKDRIMTNLRNAITEDPGRFADAQESWVDAGLAQLFTYAKDLITKPEVKRLTKRNKRFVVVMGPEMYDLFRSIGYTDIIEEKDGVTEECFMPKVPEPQGPVTLPGTYRAYMEDIQTELECMMRHLRMQKGDFMQLSNRLAIRNIEDIFDCDGYTFIEGRAKLSWPFRFLGAMPNFSTRLLEDTYNRQCLFDPENKDCYTDALFSIARDSTNGHGSEFDRKVKAMVRVEMDYLLATWDVPDIATDDEIISAFKKALRDNPSQVETCFELLQTFVNQGRRSSRLQKILEHRMPASLAADVLGIQPQDDANLVIKQARDRMSAIKKEIVARAILAIARERKDVQLLRESKRIQQGAPPPLWPVGLENIGNTCYLNSILQYLYTLTPIQALVKSYGVMELSENDVSDRRIGASKSKVSLLDLLVSQEFVKELNKLFLELQTVPVGPTQPTQVLANTVLLTDTQLQTVPETGSSNMIFSAANQPSVSTDIEPFDDIFMSDAPLISPTPHGTVSLSEINPIAGGSLTPPPEIKPVDLISNVSSETLMGDDDTPMTMVPSIQPSEHIAKANVEETEVLPSKVPTAQITKNTLDRGAVQQSLQSKHEFSMQQQDVEEIFGRIIDRIQAGISSTGFVYDGIQNDFVMQTFFFRMVTYTIKKNATGQELPAKREAPEFYRYITAFPAQSDACTLYEALDRTFDRDEIEGVESISRYTAILDDPPPVLHILVQRTQDNGQKNYNPVIIDDFLDLDRYMDAPEDSDLMKRRKKGWALRKRLRSLDAVAYGNIREPSPSSLPSLVLRDEGISDMGDSVDSALVGDKEQLCRYACEQDGLPKTVFSSAQKDHEAFAIPEPAGGLADGDGRMYGRAEAEAVYKLFESEKAALNSQCQTLFDDMKKLRYRLHAVFCHSGRQSGGHYWVWIHDFKAGVWRKYNDTWIEERAEILPELNKGSDPYYLCYVLDKDVDFFVDVPQRKPRDEDDVNEGLDFNMLDNEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX38</accession>
    <name>A0ABR3YX38_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000121">
        <property type="protein sequence ID" value="KAL1892818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="363" mass="38934" checksum="2478F75AECC883B1" modified="2025-10-08" version="1">MQPHSSYTPTGDVADRHEYGVAKSRKMASTGGGRAWSEEEEVYLLQTRLQKMPYKHIAAHLKKTELACRLHYHQLSHGSSRRKRANSESSGSSGQSPTLASAATASPMYAAESAHIPRSITPPGSSGGHYTPASPHSLQLPSIHANTPPSFARSHSRPSLESPRLPSILPKPYGMTLPLPGYPTPLPEPHSAPIMASFPRIPSPNPLLIRSTTPAPVSTGPMHSSAMPSPLPPVSYSNAAIDMNRLSAAYATHKAQFWAAVSAEYGSGVSPAALEGAWERKTPSPSSCYALSAPRFSHQGPISPAASPDQHSQREAEYRAHGQSQDRTRISAILGAEANPRPSHEHEFVRRADKERAGPLMAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX75</accession>
    <name>A0ABR3YX75_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004453</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000126">
        <property type="protein sequence ID" value="KAL1892685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="173" mass="17164" checksum="D8F3A6FA1B162735" modified="2025-10-08" version="1">MSNPATLSAAKTGDGSMMATTSSGPQVTRTSSATSTSSAAPSMNAESVAASLSSIATTIAGSSPTLNSGPGLGSSSVSGFFLGKKSLSSYSSASSVGSDATVTASTNDSNIRSAAAPTAVPIDDSRSRRLKNSIKKTVSAMGSPPTTEYDQERGQSSKRLGVSPMGCSIQSHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX98</accession>
    <name>A0ABR3YX98_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Oxidoreductase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004514</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000129">
        <property type="protein sequence ID" value="KAL1892542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019180">
        <property type="entry name" value="Oxidoreductase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039251">
        <property type="entry name" value="OXLD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21193">
        <property type="entry name" value="OXIDOREDUCTASE-LIKE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21193:SF3">
        <property type="entry name" value="OXIDOREDUCTASE-LIKE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09791">
        <property type="entry name" value="Oxidored-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidoreductase-like" evidence="2">
        <location>
            <begin position="110"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="242" mass="26597" checksum="E100BFA493EB5D3C" modified="2025-10-08" version="1">MSIVRPSRASLPELWKATSLAGVSVCRKFSTTQCSAQVHLRGSYYDAVMRSPRPPSHPMPPPIFKSTTATEEISITDKELGPEARAKLLFGSPLTGPERLANLQSQGTVVNGIRIPKKPEEPENCCMSGCVHCVWDMYQEEIYQWQAAMKEAEAAAPAESQPETLNPGNPSSSAIEQAKDLTKQPPEAIVKAKKETRELTDAEKKQEYDSLFGDVPVGIRQFMLTEKKIRSHQKGSNATKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXA5</accession>
    <name>A0ABR3YXA5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hypoxanthine-guanine phosphoribosyltransferase</fullName>
            <ecNumber evidence="4">2.4.2.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">HPT1</name>
        <name evidence="4" type="ORF">Cpir12675_004512</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.8" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000129">
        <property type="protein sequence ID" value="KAL1892541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43363">
        <property type="entry name" value="HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43363:SF1">
        <property type="entry name" value="HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="118"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="219" mass="24005" checksum="765E26E0794027BE" modified="2025-10-08" version="1">MVEIEKLYVTYNDVHKLCQEAAPKILADFQPQLMIAIGGGGYVPARILRSFLKQPGSPNIPIQAIGLSLYESLPESSGGNATPNVVEAPGTKVTRTQWLDLTSLGEMDGLVGKNILIVDEVDDTRTTLEYAIKELEKDVEIARQRLGATAPKTQFGIFVLHNKDKTKKGFLPPSITDSNRYFAARTVGDEWICYPWEAADIDEHDQCAAAALAKKTASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYI4</accession>
    <name>A0ABR3YYI4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peptide transporter ptr2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_004154</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000111">
        <property type="protein sequence ID" value="KAL1893416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018456">
        <property type="entry name" value="PTR2_symporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01023">
        <property type="entry name" value="PTR2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="364"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="410"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="440"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="483"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="520"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="547"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="602" mass="67110" checksum="3440D0619302C2D4" modified="2025-10-08" version="1">MATDDVPGHIMALTGPSAVEKDVTAALFNEKKDLQVVSVKSCVFGDSPTEAELATLRRVSDKVSLSLFTIAIVEACERFSYYGTVIVFTNFIQQPLPPGSNTGASGKHGQPGALGMSQRASTGITTFNQFWQYTMPLFGSWIADKYWGRFKTICVALGIDLIGHLILIVSALPPVITKPNSSLAAMIIAIITIGFGTGGFKPNISPLIVEQLPNQHIRVETTKTGERVIVDPSLTIEHVYNWFYLFINVGALLGQISMSFAEKYVGFWLAFLLPTIMLSLCPLVMLWGRKRYVRREPEGSVLGPAVKTFMLAQKGRWSLNPMATWRNMHDGTFWDKVKPSSFAPGTKPQWMTYDDVWVDELRRGFSACSVFCWYPIYWLTYNQLNNNLVSQAATLQLGGLPNEIVSNLDPLALIIFIPICDFFFYPSLRRWKIRFTPIRKIFAGFMAGSLAMVYSCVLQYYIYRQSDCGRYPSTCDTKPNISVWVQSGAYVLIALSEIFASITSLEYAYSKAPANMRSMVQAVALFMSAISAAIGQAWVSLSEDPLLVWNYASVGIVSFIAGILFWIQFRHLDDQEDELNRLAEGNMKADNPVEPPREKASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ84</accession>
    <name>A0ABR3YZ84_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glycerate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_004018</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000105">
        <property type="protein sequence ID" value="KAL1893671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050418">
        <property type="entry name" value="D-iso_2-hydroxyacid_DH_PdxB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43761:SF1">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43761">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G13630)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="5">
        <location>
            <begin position="30"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="6">
        <location>
            <begin position="112"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1893671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="347" mass="37508" checksum="490C397FE17F4470" modified="2025-10-08" version="1">MPMSPPQKKHHIVVLELVNSPSLSFDFPHTIEYYEVSTNDQIGDRIKDATIVIASTTPITAAHLAQAPKLECIAITATGIEFVDRSLFAKAGITVTNCPQSNVDAVGEHFLALYFACRRKVVRVHDEVTGENKTWVKKGLLMSLWEQGPPLSCAQETLGIIGYGALGKKIETLARGVGFNKILIAERKDASTARSGRTLFHDVIASATTIVVCCPKSPDTIGLVSSHEFSEMRPEALILNLARGGIVCEKALANALTSGRIFGAGVDVLEKEPAGRGTSPLIPDPEKGEEPITNLTVSGHVAWYSAQTLVNLRRMVEVGVQAHVKGDMLENPESKATAVVYRGEIFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z075</accession>
    <name>A0ABR3Z075_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_004166</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000112">
        <property type="protein sequence ID" value="KAL1893383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008253">
        <property type="entry name" value="Marvel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052649">
        <property type="entry name" value="NCE102-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28165">
        <property type="entry name" value="NON-CLASSICAL EXPORT PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28165:SF1">
        <property type="entry name" value="NON-CLASSICAL EXPORT PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01284">
        <property type="entry name" value="MARVEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="MARVEL" evidence="6">
        <location>
            <begin position="9"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1893383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="177" mass="19526" checksum="6A3103456558F934" modified="2025-10-08" version="1">MTTTYGWLNFGARCWQFVWTLITTALIGNVIASNINGSSSATTTLNYTMWTLSLCWVSMFYGLAASFFSSIAVPVILVGLDGLTTVFLFVDAIVVSARIRAVDCSRLVPSKLPHNYIAWGSNHDEKRCREIQASAVFLWFLFFSFVLTLTFALIDMRRRGLKGAGGAGGPSMTQVRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0C9</accession>
    <name>A0ABR3Z0C9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004016</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000105">
        <property type="protein sequence ID" value="KAL1893669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40616">
        <property type="entry name" value="LINALOOL DEHYDRATASE_ISOMERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40616:SF1">
        <property type="entry name" value="LINALOOL DEHYDRATASE_ISOMERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046306836" evidence="1">
        <location>
            <begin position="23"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="545" mass="61302" checksum="12B9843FE42F5A60" modified="2025-10-08" version="1">MVLLRKFSLLNAAVLAITGAVAHSSKRPQLGKNAQQLLDQSMNWMDDFYDEKAGYLYDFSAAVALRHETRSSAWYAFGLLARNHGSDVKNAEKIITNIIDGQFKDPKDQWYGDYQKAPEEPELGSPAYPPTMYGSWDPNWRGFIGTTFIIMMEEFPNLLSNGTQDLILESLNNATKGDEYRVGGVDDDNLYPSYSNPSIMRAFASGWTGRRLGEANMTTGGEQYAKDIIDLFNRNNTLSEFNSGTYTGVSLYGLLLWSKYLPNDSIMRQNGPRMLLETWKAVSQLWHPGMKNMAGPWDRSYGFDMNRYVSLMSLWFWIFLGKENSSLIEKPYVMSHMADYAYAPLFAVLGAYHQSLLPAELIKGLSTFSGEHTFTASTYYPPYDYYPRNITTWLSENITIGAEAFNENVVGGPARSQTSFNPAVVQWKNGEEIMFISLYSTEKSMLVDVAPNKLKLTYPNGTADSIFSFIVASSPDKVTYSSWEDVPGITVTAQGNVNLTHSLDFAGTYGGANKPIRDFEFWNFTYSMPQSFVGTPYIELSLIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0I5</accession>
    <name>A0ABR3Z0I5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Quinate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_003996</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000104">
        <property type="protein sequence ID" value="KAL1893696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17356">
        <property type="entry name" value="MFS_HXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF34">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0672">Quinate metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="21"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="323"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="352"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="455"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="24"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00043213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1893696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="538" mass="59845" checksum="0A7B41D52328860E" modified="2025-10-08" version="1">MGLLTLVEDRPTPKAVYNWRVYMCASIASFASCTIGYDSAFIGGTIALQSFIDEFGFASMTSGHRANIQSNIVSIYQAGAFFGSLGAYCSSYYLGRRKSLLLFSLIFILGAGLMCGTTGERGLGLLYAGRVLAGIGIGGCSNMTPIYISELSPPAVRGRLVGIYELGWQIGGLVGFWINYGVDRTLASSHKQWLIPIAVQLIPAGLLLIGALFIPESPRWLFSKGQRELATKNLCWMRNLDASDKYIIEEISYIDKDIKTYNRNVGVGLWKPFLALKDSRVQWRFFLGGMLFLWQNSSGINAINYYSPTVFSSLGLKGTGTKLFTTGLFGVVKTVMTIIWLLWMIDHIGRRKLLMIGAFGGSMCMWFIGSYIKIDDPVSKNRDSVSSGGIAAIFFFYLWTVFYTPSWNGTPWVINSEMYDPSSRSLGQASAAANNWLWNFLISRFTPQMFEAWGYGVYFFFASLMLISIVFVYFLVPETKSVPLEKMDRLFDIKPVRHANRMVMEELQAGDLNRSDIEAASSDKVGSVNYTDAKDGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0W0</accession>
    <name>A0ABR3Z0W0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Chloride channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">GEF2</name>
        <name evidence="12" type="ORF">Cpir12675_003917</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the chloride channel (TC 2.A.49) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000101">
        <property type="protein sequence ID" value="KAL1893849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04591">
        <property type="entry name" value="CBS_pair_voltage-gated_CLC_euk_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03684">
        <property type="entry name" value="ClC_3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3080.10">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="ClC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45711">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45711:SF6">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7 9" id="KW-0868">Chloride</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="112"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="299"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="472"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="498"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="528"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="560"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="11">
        <location>
            <begin position="635"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="11">
        <location>
            <begin position="720"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="771"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="773"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="786"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="811"/>
            <end position="820"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1893849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="837" mass="89140" checksum="A06D6BF0D29FED32" modified="2025-10-08" version="1">MMSAAGASSLHHSGPSSRGRSSSSDNSPLEEAFGARGYGLPDSARNWAFPASAPASDAARPDRAAYEDMTAIDWILEKTKERQRLRMLGGMPGAERVGLRGYIAQLADASQVWLVLIGTGLVVGALAACMDVATAWLGDLKTGFCTGTDGGSFFLNRDFCCFGYDVDVGNKCAGWLSWSEALHVGTSRSAIGWLVEYSFFIALSVLFAYMAACLIRRYAFFAKHSGIPELKTVLGGFVMNDFLGGWTLAAKSFGLCLAVASGMWLGKEGPLVHVSCCVANQFIRLFRAIDANEARRREVLAAAAAAGISVAFGSPIGGVLFSIETLSYFPDKTMWHAFVCAMTAAVMLQAIDPFRSGNLVLYQSSYTVDWHDFELVPYMLLGIFGGLYGGLFVRLNMAVQQWKIRLSHSSLLPSPVKQVVLVALVTAIVNYPNFYMKVPTSRLVLNLFTECAQLLDDDVGLCKTGAASGATVVLLLFAAVLAFALTAVTFGLHIPAGILLPSIAIGALVGRAFGIGIELFVRAVPDSLFFASCAPDVPCVTPGTYAVVGAAAALAGVTRMTVSIVVIMFELTGALTFVLPIMMAVMLSKWVGDALSEHSIYEAWIRFNGYPLIASEGSASSAAAHVPPGRAVDHMTALVDLHVLPATGHSIASLQQMLATSSVQGFPVVADTHSAVLLGYISRTELASALTSTSLRPETPAFFVAPGSNVNSALDLRPWMDQTPLTLSAHAPMQLVVMYFQKLGVRYVLFVDHGILQGLLTRKDAWHVLNGDGRQEKQRGRREGDSGDEGDDGDDGGQSVGLLRGQAGSPDASSRGESTQQFQRAYLIVSESGGPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0X2</accession>
    <name>A0ABR3Z0X2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">LSM2-LSM8 complex subunit LSM8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">LSM8</name>
        <name evidence="11" type="ORF">Cpir12675_004041</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">LSm subunits form a heteromer with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000106">
        <property type="protein sequence ID" value="KAL1893653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01727">
        <property type="entry name" value="LSm8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034103">
        <property type="entry name" value="Lsm8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044642">
        <property type="entry name" value="PTHR15588"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588">
        <property type="entry name" value="LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588:SF9">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1893653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="99" mass="10685" checksum="FDD755196C8F5598" modified="2025-10-08" version="1">MATLGSYLDKKVLLVTADSRIIVGTLVAADNNTNLVLKEAEERSIRTPDDEEPSSSVPLGLYLVRGDNVCTIGLVDEELDSNIDWTKVKGSEIGGIKHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z106</accession>
    <name>A0ABR3Z106_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">U6 snRNA-associated Sm-like protein LSm1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">LSM1</name>
        <name evidence="9" type="ORF">Cpir12675_003895</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the heptameric LSM1-LSM7 complex that forms a seven-membered ring structure with a donut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
            <location evidence="6">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000100">
        <property type="protein sequence ID" value="KAL1893877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01728">
        <property type="entry name" value="LSm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034104">
        <property type="entry name" value="Lsm1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044642">
        <property type="entry name" value="PTHR15588"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588">
        <property type="entry name" value="LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588:SF8">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Sm" evidence="8">
        <location>
            <begin position="54"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="197" mass="21190" checksum="4211929F99ACC328" modified="2025-10-08" version="1">MDVPEGASPGMMMLGMAAPGGPNGHEGGGSLDNGGNGASNGPPAVPQLPPQMFTTAAQLLDLTDKKLVVVLRDGRKLFGMLRSFDQFANLVLQSTTERLFVPPSSPTTPGLFTDIDRGVFLVRGENVLLLGEINMDLVEEGPDGLELPPRGYERAPLDVIQKEVRRLRELEKTRETRKNKKLAEVGFEGELGAEAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z121</accession>
    <name>A0ABR3Z121_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_003907</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000100">
        <property type="protein sequence ID" value="KAL1893887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046303044" description="Peptidase A1 domain-containing protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="449"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="4">
        <location>
            <begin position="41"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="640"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="664"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="685"/>
            <end position="716"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="845" mass="92341" checksum="2BC29118A229310E" modified="2025-10-08" version="1">MRYILPLILASAVSTASADESDLNLAPRSLSGSSWLGIDGNWSATSFRAADQEVSLFVSTTLSEHWLVDKGGCITNDPLCIKDRGGTVNYTSSQDWKTLGHWSLGLSYLGVAANAEYGTGIFGATDDLTGDNLDMKDALVGTYNTTEFYVGLFGVGVVRGKFGTESVDAPFYEMVEDEGWFPSYSYGYTAGAYYKNTPSSLTLGGYDASRLPTQPSNIDFTLSRDTMIPRVLVRGIQVSTNNSAMPSNWDSKPQILSNFTNSFHAIIDSSTPYLWLPEPVIEDFASAMNLTYNRTLEAYVITNEQMAALKQDDGFEFTFTLSSYDNNNSFGTPLSVDGVVNVTLSGAAFAHVLQYPYKDQAINFGDHDVPYFPIKKASDDNFILGRTFLQEVYLLTRYDSASFQLHQAAFPSDPIKDRNIQPITQPLNSLYPDPDSDQSEEKKGGLSKAALSGIIAGGGSAVAFIGMGIWWLLQRRKGNKAQVREIEAARSLAYNDYKLPNTPNSTFSSTGDHSVHGAGTYRQSQMLGVPAVEVAEVPTSPAFAEVGAEQGHQVFELPCNQITGPVELDSESQIFTPQESEFGDFSGRSVTPYEFARRKIDLQLQGPVPPYSPGDYKPNSSEKVAMLQVEYLPDSPGFIPRPFPSPLTPGLSSDWDAQSDDPVSSMASSPTSSRFAPSIRRCPNGTISSAGSRESVSHTSISRASSLRIVQTSSSENSRHHGVNLENSQLSGQESAPGVSHPAPAFFSRPATLSILAKRERSRHMSASTLGSNFTDTEDEMAQVSQRLALSIRPTPHNWDALERAMDSPHSQRSQNSQNRIDATNDLVHVPQVAERRYSWEENRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1E5</accession>
    <name>A0ABR3Z1E5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ndufs2, NADH ubiquinone oxidoreductase 49 kd subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">NdufS2</name>
        <name evidence="7" type="ORF">Cpir12675_003673</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the complex I 49 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000091">
        <property type="protein sequence ID" value="KAL1894444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.645.10">
        <property type="entry name" value="Cytochrome-c3 Hydrogenase, chain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01358">
        <property type="entry name" value="NDH1_NuoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001135">
        <property type="entry name" value="NADH_Q_OxRdtase_suD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014029">
        <property type="entry name" value="NADH_UbQ_OxRdtase_49kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022885">
        <property type="entry name" value="NDH1_su_D/H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029014">
        <property type="entry name" value="NiFe-Hase_large"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01962">
        <property type="entry name" value="NuoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004739">
        <property type="entry name" value="PRK06075.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11993:SF10">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11993">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 49 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00346">
        <property type="entry name" value="Complex1_49kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56762">
        <property type="entry name" value="HydB/Nqo4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00535">
        <property type="entry name" value="COMPLEX1_49K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <keyword evidence="7" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="NADH-quinone oxidoreductase subunit D" evidence="6">
        <location>
            <begin position="204"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1894444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="474" mass="53611" checksum="2F1A463161635537" modified="2025-10-08" version="1">MASLYRLATRGAFFGTRLARFPVKPSAFAAPRLFSTTIRRRADVYQGTRLLPTDADFVSSGDPYEGPTPPGEQVKRAHERSDISHRKIRHYTVNFGPQHPAAHGVLRLILELEGETIVRADPHVGLLHRGTEKLIEYKSYMQALPYFDRLDYCSMMTNEQCFSLAVEKILNIEVPERAQYIRTLFGEITRVLNHLMSVLSHAMDVGALTPFLWGFEEREKLMEFYERVSGARMHAAYVRPGGVHEDIPLGLLDDIYGWATQFGDRIDETEEMLTDNRIWIDRLQGVGVVPATEALNLSFTGVMLRGSGVPFDIRKNQPYDAYDKVEFDVPVGANGDCYDRYLCRMEEFRQSLRIIHQCLNQMPEGPVRVEDYKISPPPRTAMKENMEALIHHFLLYTKGYSVPPGETYSAIEAPKGEMGVYLVSDGTERPYRCSIRAPGFAHLGGFDHVCRGHLLADAVAVIGTMDLVFGEVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1H0</accession>
    <name>A0ABR3Z1H0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Clr5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003648</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000090">
        <property type="protein sequence ID" value="KAL1894471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025676">
        <property type="entry name" value="Clr5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788:SF3">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14420">
        <property type="entry name" value="Clr5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clr5" evidence="2">
        <location>
            <begin position="28"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="705" mass="77691" checksum="0AC376ACFA8D2E71" modified="2025-10-08" version="1">MDSSRCKISSPTEALRDKDLEYTVLPTERDWDARREEIIYLYRDREYTLNDVLKAIQQKYRWKVTPRMFKTRFDKWGIRKYQKHIPRRERPSKARRRPALTSVTLAIRNSSDAPDSGRGPTDFGFCSLPPPLSVSPSTAGSGYSASAAAAGVTIAHYPYSYTPKDTLPTPPLQSSPKTGYSYVPQNSLAAYSQYALSSQAPTAPRSSTTSPAIYAPQHHHATSMPMLPVSAGSIPMQVVPQHVMSPPNTYLPRSSTFDPTPESYSLDYADSLSASSPLLPLTVESKPSAATSATASSFNFGSSISRHSSSKCLGGLSCSGTTLRCNAELLRLVPADIASNGIKSQVDMYQNLSNSVAFLTRLRGHIRKCCQDEEFVVRAEPEMQNHVRHLVTNIYPALCSGIVGLVKVTTSNVVLGSFLSTLETEAIAIQGLEHPVSQLAMCLQNLFLIHPQNGFSSLIEDMSQQMGQQLFETFGRGSPVGLYHVLEGRCSYLVDDGVLVNMDGLLDLACRSLQSQSQNNETEMFRSMVIFDPVTSSTGSTTANGAASQEGHWVEARAVIELIYKVARIKLDIKETDPSISGLTENALHRCSEFQQAAAGDPHSKRAQTELAIVNALVPRIYLIMAQNLYYRGIKSADEALRNQALQCLEDSLERSSKYQRRSKLFSLSLDISRRMFNACNDSQALVELQQMEGRFRPPPALGIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1X2</accession>
    <name>A0ABR3Z1X2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">isocitrate dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="6">1.1.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Isocitric dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">NAD(+)-specific ICDH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">IDH2</name>
        <name evidence="15" type="ORF">Cpir12675_003613</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-threo-isocitrate + NAD(+) = 2-oxoglutarate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:23632"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.41"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Octamer of two non-identical subunits IDH1 and IDH2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.41" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000088">
        <property type="protein sequence ID" value="KAL1894624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004449">
        <property type="term" value="F:isocitrate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004434">
        <property type="entry name" value="Isocitrate_DH_NAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00175">
        <property type="entry name" value="mito_nad_idh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835">
        <property type="entry name" value="DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835:SF34">
        <property type="entry name" value="ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0520">NAD</keyword>
    <keyword evidence="10 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="14">
        <location>
            <begin position="54"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1894624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="383" mass="41196" checksum="9CA1BD8277A2339B" modified="2025-10-08" version="1">MLALRSISGAGRQCMRTAVPRATPSFAIRAQRFYSDKAEVAKYHGVKDAQGRYLVSLIEGDGIGPEISEAVKEIFAAAKTPIAWEPIDVTPILKDGKTAIPDSAIRSINKNKVALKGPLATPVGKGHVSLNLTLRRTFNLFANLRPCRSVAGYKTPYDGVDTVLIRENTEGEYSGIEHVVVDGVVQSIKLITREASERVLRYAFQQAEAIGRKKVRVVHKATIMKLSDGLFLNVAKEVAKDYPNIEFDAELLDNTCLKMVTDPLPYNDKVLVMPNLYGDILSDMCAGLIGGLGLTPSGNIGDECSIFEAVHGSAPDIAGKGLANPTALLLSSMMMLRHMGLNEYATRIEKAAFDTLAEGKALTGDLGGKASTSDYASAIIAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z232</accession>
    <name>A0ABR3Z232_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ubiquitin-conjugating enzyme E2 6</fullName>
            <ecNumber evidence="5">2.3.2.23</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">UBC6</name>
        <name evidence="5" type="ORF">Cpir12675_003747</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000094">
        <property type="protein sequence ID" value="KAL1894269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23799">
        <property type="entry name" value="UBCc_UBE2J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="259"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="UBC core" evidence="4">
        <location>
            <begin position="6"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="188"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="196"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1894269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="279" mass="30169" checksum="7A5EC2408ED87EC7" modified="2025-10-08" version="1">MATTKAARTRLTREYKSIQTNPPPYIDAHPSESNILEWHYVITGPEDTPYHNGQYWGTLVFPPNYPFAPPAIRMHTPSGRFQTSTRLCLSISDFHPKSFNPAWEVSTILIGLLSFMTGDESTTGSITSTHAQKKQYAARTRWWNSTGGGSQNSAATKGNVKAGDGGAKFREQWPELHEQNLKWMEENDIDPATGNSRTSGAVAGSSGSSTSCVPPLGITGAAGSSNGSGSGRANQAQAVVDAVVQQRDVGSGWASHNRILIFGSFVFFYVLLARLLNST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2F1</accession>
    <name>A0ABR3Z2F1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAS1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003522</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000085">
        <property type="protein sequence ID" value="KAL1894781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040200">
        <property type="entry name" value="Mug57-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28156">
        <property type="entry name" value="FAS1 DOMAIN-CONTAINING PROTEIN YDR262W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28156:SF1">
        <property type="entry name" value="FAS1 DOMAIN-CONTAINING PROTEIN YDR262W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="13"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="163" mass="17915" checksum="46BA5BE5B5ACDA2A" modified="2025-10-08" version="1">MTSRSPSPPVSGPVILSDVMGSNRTISLFTSSAREVDPVDKRLNDPKISTTVLAPLNNAISDLPHKPWENPGDYTALGANAYEGPDGRAKAKENLRRFVEAHLVPVAPWVEGDRVKTLEGTEVWWEEKDGKKTIQPDGIEVSTISNKVANGEVWIIRGVRRFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z314</accession>
    <name>A0ABR3Z314_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycosyl hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003679</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000091">
        <property type="protein sequence ID" value="KAL1894450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011613">
        <property type="entry name" value="GH15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045582">
        <property type="entry name" value="Trehalase-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31616:SF0">
        <property type="entry name" value="GLUCAN 1,4-ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31616">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00723">
        <property type="entry name" value="Glyco_hydro_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19291">
        <property type="entry name" value="TREH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trehalase-like N-terminal" evidence="2">
        <location>
            <begin position="20"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="GH15-like" evidence="1">
        <location>
            <begin position="290"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="679" mass="77400" checksum="011E6B7F2AC62693" modified="2025-10-08" version="1">MVDGQVFQGAARSRRGGYLPIENYGMIGNMHTCALIGMDGGLDFMCWPDFDSPSVFCRLLDKDKGGYFSIAPPPHISCTTKQQYLPSSCILQTRYIHEDGVVDLIDFFPRPKSTILPTRRSHTAYREATQVQEELKKWLVRRVECVRGAMVIDVEIFPAFGYAKVPHETVLEQGPHSQTGDNSKVATFHTKDVRLQLDVTVDKGEHEGPHEGECPIIMFQKVEKEGMLGPGVVAHITLKEGQAISFVLRNDLEQHVTTNITSQVLDAQQHDTQEFWYKWISKSKYKGRWREVIHRSLMILKMLTYEPTGAIIAAPTFSIPEDIGGTRNWDYRYSWVRDASFTIYILLRLGFVAEADSYMEFMMERIQYSLGPDGALPIMFTIHGETDIPETELTHLDGYRGSKPVRIGNGAAFHQQFDIYGELMDAIYLYNKYGKPVTWDNWVLIRNMLDYVLTLVNESDMSIWEVRNNKQNFTYSKIMLWVAFDRGIRLAEKRCLPCPNRSRWLEARDGLMEEIMKKGYNKSLKCFVQSYENNTLLDSSILIAPLVFFISPNDPRFLSTIEKILMPPEKGGLTSTGLVYRYDTEKSTDGVGGREGAFSMCTFWLVEALTRASVYEPKYGPYAVSIFENMLSFSNHLCMFSEEISRSGEQLGNTPQAFSHLALISAAFNLDRVADSMKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3F3</accession>
    <name>A0ABR3Z3F3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Methylcrotonoyl-CoA carboxylase subunit alpha mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_003510</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000084">
        <property type="protein sequence ID" value="KAL1894815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06850">
        <property type="entry name" value="biotinyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050856">
        <property type="entry name" value="Biotin_carboxylase_complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18866">
        <property type="entry name" value="CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18866:SF33">
        <property type="entry name" value="METHYLCROTONOYL-COA CARBOXYLASE SUBUNIT ALPHA, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0092">Biotin</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="9">
        <location>
            <begin position="1"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="8">
        <location>
            <begin position="112"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="7">
        <location>
            <begin position="620"/>
            <end position="695"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1894815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="697" mass="75791" checksum="57F453549DDEB1BC" modified="2025-10-08" version="1">MIANRGEIALRIHKTAHRLGIQTATVYTDPDASSQHAAVGNYSFNLGPARGYLDSEKIIGLAKAHGIQALHPGYGFLSENSAFAARCEQEGIVFVGPPAQAMADMGHKARSKEIMESSGVPCVPGYHGPQQGEDQLLGHATKIGFPVLLKSVRGGGGKGMRIVKAESDFLAQLRSARAEANASFGDGGEAMLVERYIERPRHVEVQIFADKYGNCVALGERDCSIQRRHQKILEESPAPHLDALTRADLWSKARTAALAVGYVGAGTVEFILDKDSGQFFFMEMNTRLQVEHPVSEMVTGTDLVEWQVRIASGEKLPLTQSDIEKNISARGAAIEARIYAEKPEEGFMPDSGKLIYLRTPATNENVRIDAGFGEGDVVTEAYDGMIAKLIVRADDRTTAIQRLDRALAEYEIVGLGTNIEFLKRLCQSPAFVQGDVETGFIEKHHDELFAAPLYQDEVFVQGALALLLSAADEAQTQSFQPPPGGASLGFVGIANPGEADSIGTRSFSFKVLDVRNESDVTAVVVLYPTGNRMYDVNVTTKAGNNSDTRSYKSLTTSCALSAESCTKADVTTYFPQQRITSKVVTQTQTAGSDQTTVVVFQHGKKHELELLSPTWYDTALGIKKVSRAVVAPMPCKILKVEVGHGQEVKRGDPLIVIESMKMETVIKAPHNGRVKRVMYQPGDICKARSILVEFEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3K9</accession>
    <name>A0ABR3Z3K9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000086">
        <property type="protein sequence ID" value="KAL1894660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="233" mass="24615" checksum="322689B94C49ADCB" modified="2025-10-08" version="1">MSGVSRTAGARLRKTFKYPDDSDSDLDAHSRAELDEQEQEALIRNLAAQNAVRNAQFHHALRFLPLLASAAYVLPLFYSSSSGGARRALVPSLLSLTSLVATCFLAHQLPVQVTGFAFLDDLCARDSTSSASKIAGNRRAVRTGFLRRGEPGGLAGESPLERYLPYLNVALGVLAAVGGTLGPARGGGVWWLDGVLAGLPLGVLAVVVGAKMMMAGVDPETELSALKYDYKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3P6</accession>
    <name>A0ABR3Z3P6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Component of a membrane-bound complex containing the Tor2p kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">AVO1</name>
        <name evidence="5" type="ORF">Cpir12675_003812</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000096">
        <property type="protein sequence ID" value="KAL1894124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031567">
        <property type="entry name" value="CRIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008828">
        <property type="entry name" value="Sin1/Avo1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031313">
        <property type="entry name" value="Sin1_PH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13335">
        <property type="entry name" value="TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13335:SF1">
        <property type="entry name" value="TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16978">
        <property type="entry name" value="CRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16979">
        <property type="entry name" value="SIN1_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CRIM" evidence="3">
        <location>
            <begin position="364"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="SIN1-type PH" evidence="4">
        <location>
            <begin position="752"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="82"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="248"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="533"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="119"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="161"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="252"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="268"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="545"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="564"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1894124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="855" mass="92913" checksum="7643A3C1F6B6A4B5" modified="2025-10-08" version="1">MSVMQTEDLVAYQLRTSYLDEIADGVGERLITLNDGFLNTGPFKATGWKANPTHVKRTYSPPIPTAIASEYFQAPRAVGHTLEDEPDVFGPQGGMESSAVTPIAGPKRRRGRGHRPPDQEEDSSDLSDDSEDEADPTAQSGQHKEHRREPSQIKFTKMPVRSRAGSSPSQSSSLRPPMMPVAASPRASLSSPLSAARRGSQSALETVVERARRDTVTSSEVSSENELDTMQRQRAVAAVAAVVVARAKAMKPQSQTQKKQLQISSLHEDEDEDDDDDDDDSDASSARFPDTLDSVSILDTVDNPMQVNPPASPTTQLVGTPPRKFMRRSTIRRSPAPVISRVLTALPPARPISAIRPLSMIQPKSLLSEALKKKTSGVPFARFANLSGQGERKPPFCVRIFAPFSNQSSTPFDVQIRRDVSDDTGSSKPVTVAQLIGLSLLRYIEEKREPPLPENKMGVNWWTLRMMEDGEVDDDFPPLERTKPLASFVTANNGPGSGGAGVGGAGGGGGVRGRGRANSAHYDDFALVMASDSERRDNLQQTAEYADEEADIDDALGVGSPTSNKPPEPAAPPPPPPAYMPPAYINPLLTTTFRNQNIIPADAPQAPASSNRMRGQHKLLRIYILTSDIAASQLVTVDVTTDMYLAEVLDIVCQKRQLDQANHILKIPGSGAVARLDRPVASLGNVSDLELYRRRFATDGPLTSSGSPTSASPKVLPLVESSQHSRRAKKQFMGIHPLTREALKQDELGSANYKKYTVWRKQTMRLVGTSERSLVIDGEYIHIIPAAGASGKTTTVHFSNAVGCKVLRKHPTNLKLMVYKGTESKRYDFEAKSAEEASEIVIELKKGIAPYLEGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z458</accession>
    <name>A0ABR3Z458_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003470</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000083">
        <property type="protein sequence ID" value="KAL1894825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16464">
        <property type="entry name" value="RING-H2_Pirh2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039512">
        <property type="entry name" value="RCHY1_zinc-ribbon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21319:SF0">
        <property type="entry name" value="AND RING FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G08900)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21319">
        <property type="entry name" value="RING FINGER AND CHY ZINC FINGER DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14599">
        <property type="entry name" value="zinc_ribbon_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="306"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="31"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="665"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="680"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="690"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="725" mass="79302" checksum="C89DD6528DD09EAF" modified="2025-10-08" version="1">MASLVSEFIINPVLRQARRFSEISRPSVVDLSGGENEFPQKDVGSSLDPSAKGFPESAIDSATPSDDFPTSAFMSTSNVSPSLPSHVDPQTNRQTMSLLSVHKDDLNQGQEAWALEDASQSSSRSASPQLFVPLDAQGVCELEERELPDDDGMTEMRASIRSIQNMDVCTREKGRLLHHTLMKSHLAFKAFHSRQFASDIPDSPQTWQIQKNLAVGSPLSVGPLSTSLASLKFWNHEDEAETFTLTEQDITPTFHTPPHSNEPYIGCKHYRRNVKLQCSTCSKCACISTSIQYSHKCIERATDCNCPICEDYLFTSRKAVVFMECGHSIHRSCHDKYLATGSYKCPLCSKAIINTEALFRSIDLAIQNQPMPEEYSNTRALVFCHQCTTRTTVPFHWLALKCGLCDSFNTTHLETVSPPTGAQVSTEQIAAAPLASIDGVGRAVETMLESASASRTGQQAEMMSQIAADDNSGILAQPQIPNIQVALVQQAMTARTAAMRSMEDPVSPSQCEEILLTNQTGPEQPEQTILIAGPSLEAPIRELDADSVERFLQQFDQDLDQDILHLWDNDNNEITGSNEGSAIGVGAITRNALNNLQQAIHSNLLDNNDVASVASMTRNALNTFQQALQSRLDNNLYHDLESAGNDESLRRNTLALLHHALHGNVVDSDDDADGEALVSDPKEPGKGDSDCDESAEDNEDGASSTADSLFAYEGPEDDFILPGHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4U2</accession>
    <name>A0ABR3Z4U2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">SAT4</name>
        <name evidence="13" type="ORF">Cpir12675_003303</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000076">
        <property type="protein sequence ID" value="KAL1895286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13994">
        <property type="entry name" value="STKc_HAL4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343:SF558">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343">
        <property type="entry name" value="SERINE/THREONINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="206"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="56"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1895286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="489" mass="54780" checksum="C1216C127388E84B" modified="2025-10-08" version="1">MSPKDSPLSSRASSIKSIDRPKKSPHAASPDSVPEEQQPKPVSGGIKLLSRMFYGRDSTPRTPTESTRPRGSSFTSSPNTQPTSNPSNIARTTTTPVGAGSIAPPARKGTLDPNKTKMPRFYLDPDPEGPGHCHHSHHLKSSVRQEKLSSMWKSWLGKHYNDSNNETNNEDLSLMSGFADMKLEKKSSNERKAILNGTATFEEKYGKCHEVIGKGAFGIVRISHKRVQNGSERLFAVKEFCKREDESERKYSKRLTSEFCISSSLHHSNVIDTLDLIKDERGVYCEVMEFCAGGDLYTLILAAGKLETKEADCFFKQLMRGVNYLHEMGVAHRDLKPENLLLTTNGALKITDFGNGECFRMAWEADAHMVSGLCGSAPYIAPEEYVEKEFDARAVDVWACGVIYMAMRTGRHLWHIAKKDEDEFYARYLEGRREEAGYAPIESLNRARCRNVVYSILDPNPKRRLTASQVMKSEWGREIKVCKAGEEGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z541</accession>
    <name>A0ABR3Z541_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">General transcription repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">TUP1</name>
        <name evidence="9" type="ORF">Cpir12675_003125</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000069">
        <property type="protein sequence ID" value="KAL1895734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013890">
        <property type="entry name" value="Tscrpt_rep_Tup1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08581">
        <property type="entry name" value="Tup_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Transcriptional repressor Tup1 N-terminal" evidence="8">
        <location>
            <begin position="19"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="343"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="378"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="419"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="464"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="517"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="559"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="87"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="111"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1895734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="595" mass="64538" checksum="489A5E0E31ADC77C" modified="2025-10-08" version="1">MSMYPQHPPRMGGGPPNNRFNELLEQIRSEYESQIRSGENYEHQIQSQVSELQLIREKVYAMEQTHMTLKQKFEEEIAHLRRQLEAARGGPQGSMGGPPPHPVQQPPAISGGSGLFNGIMSGAGQGGLAPPPQQQPPQGDQMPPHGQMPPGPTGLPVPPPPPGPSQQPPFQQNAYGQAPISNGMGPQPPQSTASPGPRGRGMGRPPPTAGPATPQISNPMPFPGPAQSPQVSHPTPDHGRMGPRPSQGPSSMEVDPDRLPPQLKKTGSDWLCVFNDAVPRTLDVDLVHTLTHESVVCCVRFSHDGKYVATGCNRSAQIYDVQTGEKICVLQDETADVTGDLYIRSVCFSPDGRYLATGAEDKLIRVWDIQNRTIRNTFSGHEQDIYSLDFARDGRTIASGSGDRTVRLWDIESGSNTFILTIEDGVTTVAISPDTKYVAAGSLDKSVRVWDIHQGYLLERLEGPDGHKDSVYSVAFSPNGKDLVSGSLDKTIKMWELNTPRGSANPGPKGGRCIKTFEGHRDFVLSVAFTPDGLWVMSGSKDRGVQFWDPRTGSTQLMLQGHKNSVISVAPSPTGGYFATGSGDMRARIWSYRNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5Q7</accession>
    <name>A0ABR3Z5Q7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_003367</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000078">
        <property type="protein sequence ID" value="KAL1895138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF32">
        <property type="entry name" value="MISCELLANEOUS ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="207"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="213"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="227"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="280"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="862" mass="95027" checksum="ED92747E622D755F" modified="2025-10-08" version="1">MAAPRPVQHPLQPEPTKSSTNMSPNPVPVPGLAPAGPEAYLPAPYGKACAECVKTKRKCMLPASSGECQRCHRLHKVCHRPPTTGVRKRATGSRALSRAALEEKLDNLVNLLQQKSGGQSAAPQPATSSAAVSAAVAIVDVSSTPGSSVSALSPGRIGVGADDTGSASNDAACLTAPSSNRATLQDLAEVSASASSTVLLARQPDLTQSSLKPAQQARQQQQRNQKPPLPPLPQPYPLQQQQQQQPHQQPQQQQHPKPSSNAPQPLHHTRNTHLVPLQPPAQQTSTQPPLQHDSTQPQQSSMYPYSILSVSSLGSQMPSTASKPPPTTKRAVMPNIFNPAREFINNYIQGDILHHKSSATETPSWVPQEFTPQEEEAMFNRFRTENMKYFPFVYIPSNTSASCVKNERPFLWLAIVNVTSKITSVQTRMSKLIREVISQLIMTDQSATLDVLQGLVVFLGWGNHQMSNDLKPFMCMYINITMGILSVININKTQNEYLASQDPNPPPSFSDREMDEKRAALGCYFISSSLSYFLHIGSSIPSMPWMPYMEDYLLEIALKQDSPYDNILVIMTRCQLVTMEATKLFREINDRNDSKIGSTIITQTMQCKMLQSRISEIKEMISPEIRDNYIVQSVVNTAEIAIHDVSCWDIPPSEPWVNTERVNILGHCFHLLRDWFDSFFGVPVKTYMSLPFNVWFQIFRNCCILCKLTTIDQKGWDRAYVRQTLDVIAVIERISNNFTSAASESGIVVDTSPGDDVFSRSRRPLFHMRSAWESHLIKITGTAFTGTFGAGIGAITPADSTLDNNGQVAGAPSMVMSSFTANTQATTTTTNGSVPQPLGEAISLDFGIDFDWFSDIYSYGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5Z3</accession>
    <name>A0ABR3Z5Z3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Folylpolyglutamate synthase</fullName>
            <ecNumber evidence="17">6.3.2.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Folylpoly-gamma-glutamate synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Tetrahydrofolylpolyglutamate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">MET7</name>
        <name evidence="18" type="ORF">Cpir12675_002950</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16 17">
            <text>(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + L-glutamate + ATP = (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n+1) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10580"/>
            <dbReference type="Rhea" id="RHEA-COMP:14738"/>
            <dbReference type="Rhea" id="RHEA-COMP:14740"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:141005"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>a monovalent cation</name>
            <dbReference type="ChEBI" id="CHEBI:60242"/>
        </cofactor>
        <text evidence="17">A monovalent cation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 17">Cofactor biosynthesis; tetrahydrofolylpolyglutamate biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 17">Belongs to the folylpolyglutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.17" evidence="17"/>
    <dbReference type="EMBL" id="JAWDJO010000063">
        <property type="protein sequence ID" value="KAL1896035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="entry name" value="Mur ligase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="entry name" value="Mur-like, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023600">
        <property type="entry name" value="Folylpolyglutamate_synth_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136:SF5">
        <property type="entry name" value="FOLYLPOLYGLUTAMATE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="FOLYLPOLYGLUTAMATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038895">
        <property type="entry name" value="FPGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="MurD-like peptide ligases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="MurD-like peptide ligases, peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01011">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 17 18" id="KW-0436">Ligase</keyword>
    <keyword evidence="13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 17" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRNR" id="PIRNR038895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1896035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="542" mass="59693" checksum="B4E79621FD6A60F4" modified="2025-10-08" version="1">MVPTSRLSRNGALALLAARSHTASTRCSIRTLTHTLVSDNRGRSYNVSQGSSYKCPNNKLTRLSQDAIETLNSLQSSNAVVEARKKAGIKPNQASIKDMHAYLARLGHSLADLDRLNIVHVAGTKGKGSTCAYVNSILASWQRVHGTPRRTGLLISPHLISVRERIQLNSQPISETLFTHYFFDVWEKLRQAETETIQMGSSATTERPSYARYLTLMAYHIFLEEGVDVAVIETGIGGEFDSTNLASKPAATGISMLGIDHVFVLGDTVEKIAWHKAGIMKTGTPAFSVPQVPAAEKVLQDRAREKTVGLQFVDLDSRLEGIKIKPDADFQKSNASLAIRLAETALQKLDPEFAVKTASTTALPSEFIDGLQSMVWKGRCQIKTEGKVTWHLDGAHTIDSIKVCSHWFAQECRKNTKVLIFNQQDRKEAVDFLDTMYKIIRDNKVHFSHVVFCTNVTKNPKTKDLVNHQADTENIQALTVQNNLASKWRQIDPTVSISVAPTVNDALDIARELASGLRDVKGVEVLVTGSLHLVGAVLSTME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5Z4</accession>
    <name>A0ABR3Z5Z4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NADH-ubiquinone oxidoreductase 30.4 kDa subunit, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ALI1</name>
        <name evidence="6" type="ORF">Cpir12675_002939</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the complex I 30 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000063">
        <property type="protein sequence ID" value="KAL1896026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.80">
        <property type="entry name" value="NADH:ubiquinone oxidoreductase, 30kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01357">
        <property type="entry name" value="NDH1_NuoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010218">
        <property type="entry name" value="NADH_DH_suC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037232">
        <property type="entry name" value="NADH_quin_OxRdtase_su_C/D-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001268">
        <property type="entry name" value="NADH_UbQ_OxRdtase_30kDa_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020396">
        <property type="entry name" value="NADH_UbQ_OxRdtase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01961">
        <property type="entry name" value="NuoC_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004733">
        <property type="entry name" value="PRK06074.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10884:SF14">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10884">
        <property type="entry name" value="NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00329">
        <property type="entry name" value="Complex1_30kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143243">
        <property type="entry name" value="Nqo5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00542">
        <property type="entry name" value="COMPLEX1_30K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NADH:ubiquinone oxidoreductase 30kDa subunit" evidence="5">
        <location>
            <begin position="112"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="263"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="286"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1896026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="296" mass="33820" checksum="B4A60D774907DED7" modified="2025-10-08" version="1">MASRLSRGRTVATALQSAKAQRQLPHTQQHSMAALRCLSATSTQFVAMPSDTPNMRHAKRAPASTTLHAPIVNPADKYTTKADNLHKYGAWIMGCLPKYVQQFSVWKDELTIYIAPTGVIPVFTFLKYNTSAEFTQLSTLTANDFPTRDQRFEVVYNLLSVRYNSRIRVKTYCDEVTPVPSVTPIYDGANWYERETYDMFGIIFSGHPDLRRILTDYGFEGHPLRKDFPLTGYTEVRYDEEKKRIVYEPLELTQAFRNFEGGTTAWEPVGPGVDHRPDTFKLPTPKPEEKKEEPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z657</accession>
    <name>A0ABR3Z657_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003099</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000068">
        <property type="protein sequence ID" value="KAL1895766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895:SF67">
        <property type="entry name" value="AMIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="160"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="598"/>
            <end position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="622" mass="67398" checksum="D104607FF2423E3F" modified="2025-10-08" version="1">MSFVDYPKAHQAEQWSKGPEVDDKNPVLRGPLLAVAGTIVSKLPALQKFLWSNAGFGSLRDYVALAGVIPRFVPLVIPVENNDRAVIPNATNLDGVLYESAPADLIGRYHTAADYHNAYKSGNVTPLQIAEALHSLILRGQDPRCKYDNAWVDSHGADNIALEAARQSTERWKQGRPLGLLDGVPFGVKDDLDVKDYVSHMGLKYQSNLSFQKPAEETIHPVRKLQEAGAIMIGKNAMHELGCDTTGCNPAWGTPTNWHNTSYYPGGSSSGAGSSIGAGIIPFALGTDAGGSARIPPCFNGVYGLKTTHNRIMSLTHTMCVVCPMASTVADLTAAYRVTAQPNLEDGITSCFVPSPLRDSSAKKCIGIEKTWVSKSDPQVLEQFNNGLDYLKTLGYEVVDITIPNLKECQLAHGAACLTEMAEQHRSRIGKDSNWMKTVNNATKIMLGVGSSTPGLDLIKYHQVRTVLMEHLAYIFKTYPGIIILSPTSPQIGWPRNPNDEAYGVNDANISLRNMMYIFLANMVGCPALTAPIGFVNPEQGEGQLPIGMMAMNEWGAEESLLAWAADTERYLNEKYPGGRVRPAGWVDVLKLTQDRANGASKASVPDSKGAATDVQNKSLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6P1</accession>
    <name>A0ABR3Z6P1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Multidrug transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">QDR1</name>
        <name evidence="7" type="ORF">Cpir12675_002885</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000061">
        <property type="protein sequence ID" value="KAL1896238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF51">
        <property type="entry name" value="QUINIDINE RESISTANCE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="314" mass="33755" checksum="F4CCB2E07401AC22" modified="2025-10-08" version="1">MATIFQKSIGEISLTVTTYLALQGCAPMFWGPLSDRYGRRPIFLSCLSVLVGACIGLALCPTNVFWLLFLLRCMQADGCASTVALSAGVIGDIVTPEERDGFYGIGNIGPMIAPAMAPAIGGVLFYPETARNIAGNGSPSVSLVYRAFIPIIGRGRLGTAPSLPKAMRIPYTNPFTIFLCPDEIYDLSEAEIGSWYIPVVSGITVSSVITGKIQDWDYRRVKARTPPGTLLPKELARLCFTPIYVCGFVAAICSWGFRLEYKAPKVVLGVVSFFSGYGMISVLSSTFTLMIDIMHTRSSAATACCYVSTALDLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7L0</accession>
    <name>A0ABR3Z7L0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Copper acquisition factor BIM1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_002920</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000062">
        <property type="protein sequence ID" value="KAL1896212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21176">
        <property type="entry name" value="LPMO_auxiliary-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046936">
        <property type="entry name" value="BIM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046530">
        <property type="entry name" value="BIM1-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992:SF10">
        <property type="entry name" value="COPPER ACQUISITION FACTOR BIM1-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992">
        <property type="entry name" value="HYPHAL ANASTAMOSIS-7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20238">
        <property type="entry name" value="BIM1-like_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047168822" description="Copper acquisition factor BIM1-like domain-containing protein" evidence="8">
        <location>
            <begin position="18"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="Copper acquisition factor BIM1-like" evidence="9">
        <location>
            <begin position="16"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF20238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1896212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="237" mass="25340" checksum="3D6541E0DFE5C672" modified="2025-10-08" version="1">MWPSLVTSLLTASVASAHILLTYPGSRGNSFITNDTFPFGMQWTYPCGGIPLSRNRTYWSVNGGSIAFQPGWFSGHASAMMYVNIGLDSDGPDGGPMNFTNQLVMPFELQGPSNGPFPGTMCLPNVQVPASLGVTAGMNASLQIVELATHGASLFACSDITFVEPDDSRIPASNESVCFNSTDFGFGEIYTAVVHEASPVRNSSAKSAAVSSQHLQNPYWPFSWPVLFFIVGLLVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7R0</accession>
    <name>A0ABR3Z7R0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ATP-dependent RNA helicase DHH1</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">ATP-dependent RNA helicase dhh1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="primary">DHH1</name>
        <name evidence="21" type="ORF">Cpir12675_002883</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="23">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000061">
        <property type="protein sequence ID" value="KAL1896237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17940">
        <property type="entry name" value="DEADc_DDX6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47960">
        <property type="entry name" value="DEAD-BOX ATP-DEPENDENT RNA HELICASE 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 16 21" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 16 21" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="4 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="9" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="20">
        <location>
            <begin position="44"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="18">
        <location>
            <begin position="75"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="19">
        <location>
            <begin position="255"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="434"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="15">
        <location>
            <begin position="44"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="434"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="455"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="474"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="17">
        <location>
            <begin position="553"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00040210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00040448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAL1896237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="579" mass="64139" checksum="832E0CFEBBBDFF2F" modified="2025-10-08" version="1">MADAIIDKLKATSISEGDEWKKSLNIPAKDSRTQTEDVTNTKGLEFEDFQLKRDLLMGIFEAGFEKPSPIQEEAIPVALTGRDVLARAKNGTGKTAAFVIPALEKINPKVSKIQCLILVPTRELAMQTSQVCKTLGKHLGINVMVTTGGTGLRDDIVRLQDPVHVVVGTPGRILDLAGKNVANLSECPMFIMDEADKLLSAEFTPVIEQLLQYHPKDRQVMLFSATFPVEVKGFSDKNMNNPHEINLMDELTLRGITQYYAYVDEKDKVHCLNTLFSRLKINQSIIFCNSTNRVELLAKKITELGYSCFYSHAKMAQTARNRVFHDFRKGVCRNLVCSDLLTRGIDIQAVNVVINFDFPKNAETYLHRIGRSGRYGHLGLAINLINWEDRFNLYNIERELGTEIAAIPSVIDKSLYVYDNPENIPRPINTAQITPARAAQQQAQAQPAGPSQNATWQGQSGFAQNAPNQGQYAGQHPGQHQSQNQSQHPGQHQSQHPSQHQGQQQHQGQYQGQYPGQHQGQGQRINGNGNGNASANGNGNTNNNHHWRQQNGRGRGGYGRGQGRSGPNGNGNRGGRQQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7X5</accession>
    <name>A0ABR3Z7X5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Acireductone dioxygenase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Acireductone dioxygenase (Fe(2+)-requiring)</fullName>
            <shortName evidence="11">ARD'</shortName>
            <shortName evidence="11">Fe-ARD</shortName>
            <ecNumber evidence="11">1.13.11.54</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Acireductone dioxygenase (Ni(2+)-requiring)</fullName>
            <shortName evidence="11">ARD</shortName>
            <shortName evidence="11">Ni-ARD</shortName>
            <ecNumber evidence="11">1.13.11.53</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ADI1_2</name>
        <name evidence="11" type="synonym">ADI1</name>
        <name evidence="12" type="ORF">Cpir12675_002802</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 3-(methylsulfanyl)propanoate + CO + formate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:14161"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:17245"/>
            <dbReference type="ChEBI" id="CHEBI:49016"/>
            <dbReference type="ChEBI" id="CHEBI:49252"/>
            <dbReference type="EC" id="1.13.11.53"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 4-methylsulfanyl-2-oxobutanoate + formate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:24504"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:16723"/>
            <dbReference type="ChEBI" id="CHEBI:49252"/>
            <dbReference type="EC" id="1.13.11.54"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
        <text evidence="11">Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="11">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 5/6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the acireductone dioxygenase (ARD) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.54" evidence="11"/>
    <dbReference type="EC" id="1.13.11.53" evidence="11"/>
    <dbReference type="EMBL" id="JAWDJO010000058">
        <property type="protein sequence ID" value="KAL1896465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004411">
        <property type="term" value="F:homogentisate 1,2-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02232">
        <property type="entry name" value="cupin_ARD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03154">
        <property type="entry name" value="Salvage_MtnD_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004313">
        <property type="entry name" value="ARD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027496">
        <property type="entry name" value="ARD_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23418">
        <property type="entry name" value="ACIREDUCTONE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23418:SF0">
        <property type="entry name" value="ACIREDUCTONE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03079">
        <property type="entry name" value="ARD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11 12" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="8 11" id="KW-0408">Iron</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 11" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="3 11" id="KW-0533">Nickel</keyword>
    <keyword evidence="10 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7 11 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="11">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <note>for iron-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <note>for nickel-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <note>for iron-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <note>for nickel-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <note>for iron-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <note>for nickel-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <note>for iron-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <note>for nickel-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1896465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="175" mass="20541" checksum="3B2EB317943A1C05" modified="2025-10-08" version="1">MKAYIYDDVEGDQRLPHDSGKAVSVEDLAALGVLYYHYDSIDKVNSLALERNYKNRDEVFVSPEKMGSVYEEKVKTFFLEHLHEDEEIRYIRGGQGYFDVRNCGNEWVRILLEKDDLIILPAGIYHRFTTDESNYVHAMRLFKDEPKWTALNRDATLENNSFRQGYVKEFLVTTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z869</accession>
    <name>A0ABR3Z869_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphopantothenate--cysteine ligase cab2</fullName>
            <ecNumber evidence="4">6.3.2.51</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CAB2</name>
        <name evidence="4" type="ORF">Cpir12675_002763</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPC synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.51" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000057">
        <property type="protein sequence ID" value="KAL1896474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10300">
        <property type="entry name" value="CoaB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035929">
        <property type="entry name" value="CoaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007085">
        <property type="entry name" value="DNA/pantothenate-metab_flavo_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12290">
        <property type="entry name" value="CORNICHON-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04127">
        <property type="entry name" value="DFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102645">
        <property type="entry name" value="CoaB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA/pantothenate metabolism flavoprotein C-terminal" evidence="3">
        <location>
            <begin position="46"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="208"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="220"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="404" mass="44861" checksum="C22A274897F27D29" modified="2025-10-08" version="1">MSATTSEAVAQEEDQYFSQNPPPRNLDAITAQAAAFIHEHANASRRVVLVTSGGTTVPLEKQTVRFIDNFSAGTRGATSAEYFLEAGYAVIFLHRQFSLQPFSRHYSHATDCFLDFMEDVDDGVHGHHVMAKQAHQAKMLKVLRQYNTAKKQNLLLMLPFVTITDYVFELRAIARLLRPLGKNALLYLAAAVSDFFVPANRMAEHKIQSTDAVGQDGKPARASKATATGAAPTPATAMVDMPETFDNFDSSPKVPRSKSLVIDLDPVPKFLKNLVDGWSPEAMIVSFKLETDPAILVHKAKYSLERYQHHLVIGNLLSTRKWEVVFVAPGKADRWIRLPIHNRKNPTVTNEGENIGGKEEKQAIVTIGDDQPLDPKILPEGDPEIEIERLIIPAVKELHDEHTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8J9</accession>
    <name>A0ABR3Z8J9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002516</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000050">
        <property type="protein sequence ID" value="KAL1896991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="73"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="179"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="319"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="562"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="193"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="203"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="319"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="350"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="363"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="933" mass="103643" checksum="DBEC1DFFA481EFF2" modified="2025-10-08" version="1">MSQSYPPGRDLVDSPTPLNANVIPDPTVPSVPAHPWMPATARAGQPTQFETFVSARKPHKYFYRMASQGDENWLSATPENSPYPPIADSNPGPSLVPPPSDGLGVSPPTEQNIWTPNSEPDDTSPPLFPPSFDAVDLIEQDYHYPSPQLLLASDSDLGMASHSPCEVPKRLSSGTINLRTAISPAPPLPSTGPNSKKSISSPISPPSPQPSSLPLPTIEAVVLHPPPSSLSPSCECDRDGSTPTPRPLNRLAPAFPPPQSALPPLLLGEIPLPTVSPFPLPPPPLFELNQDYLSLLATVPFYSINKNCTPPSSNAPVLPSPLMPIPSPTPSSPSVMPQSPITPSPRPSSLLKSHQHSVASNYRPPPPPTDGLFVTPPPITVPVPMIGPEASAKIATCSKTIPSAFSGFNSRSRLEAACSGNKLRATIYDDDEMEEIRKGEDYSFPPRKGPTQASPLTESDKSRFMSHLMSFAKHVNQKEFSSPSASITESIDMDKIQLLWKTLKTKQTQVYDLRGRMAKHRSRLSSIRSDEADISYRLIIQIRRQMKIEFPESLQETQLSTVERLFAEAQAMRAEYQRAQDEYDGLDLRLDSEEEEIASLEVCFFSALQGKLEAEDSRKEKFPKNTNLPKVPIEIFGISTDLVQTPLPTQYIKLENAVADFNLCFEELHDLVSCNSQLRDEMEYKSRFNPNFKLDIYDQELIDTFPEDRKRLSKSHMDAREAVINQLRLCISQGHMPDPAFIPLDIMFVLSDMFYSEFMPWLRKQPCDSSRVKLDPDMTLEESKSQVGPDPPDCYPLIVPSHRKIEGSLADGVKENLSKAGTIENDGVPSPFSLGYLIDKRAPPIRHELEDRRKERPVGNWLLVNTWLEHQVRSSTFCAFQLERAFEQANPHMNMPCEVWERMAMQSWYNDETLLLADDDGFIVAPMTPPVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8W6</accession>
    <name>A0ABR3Z8W6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha/beta-hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002856</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000060">
        <property type="protein sequence ID" value="KAL1896263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050261">
        <property type="entry name" value="FrsA_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22946:SF12">
        <property type="entry name" value="CONIDIAL PIGMENT BIOSYNTHESIS PROTEIN AYG1 (AFU_ORTHOLOGUE AFUA_2G17550)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22946">
        <property type="entry name" value="DIENELACTONE HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1896263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="305" mass="34541" checksum="8A92906E2264D2B5" modified="2025-10-08" version="1">MRNWIMGKEAFEETAPHHEGIKALWETKWKLACQRSVYPFQEGKYEDFEPIFQHLIENNINDGYSAEYSLAFVPTAKHLDREAEALLETDPAAANELWLRASAVLRIARLPYFAAYPEPSCPIKLKIYEMQKSIFLKAGSRWECPVQDLMVPHVYAAGNDWKEIPAYVRTPTNAATQPAPTIILMTSLDGYRCDNSVRCNRFLDRGWASVVVEVPGTGDCPADSADPNSPDRLWTSLLAWMKADGRFNMSKVMVWGGSAGGYYAIRIAHTHKDQLIGAVAQGAGCHYFYDPEWLKKADNHEYPFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9C1</accession>
    <name>A0ABR3Z9C1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA replication initiation factor cdc45</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CDC45</name>
        <name evidence="7" type="ORF">Cpir12675_002692</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDC45 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000055">
        <property type="protein sequence ID" value="KAL1896670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003874">
        <property type="entry name" value="CDC45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10507">
        <property type="entry name" value="CDC45-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10507:SF0">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 45 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02724">
        <property type="entry name" value="CDC45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="196"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="727"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="139"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="727"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="777"/>
            <end position="811"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="868" mass="95874" checksum="F7285A753E82F8CD" modified="2025-10-08" version="1">MYLPRSLLSKLYVHLQRSRHPLSPPVLILVALEPDALCACRILTRMLKHDYIQHKIQPIAGYADLEKAGQDLVAPMMQSRGGSGGVVVCLGVGGMADMGSVLGLEPEDNTASYSGVEVWLLDSHRPWNLSNIFGGYPSEVSSSDPGQAMQQAPPGVDAGKISHSYRPGTGGIIAFDDGDIDDLLSSEQEAYTALVNMPEIDDQDLGNSDDDDSEDEVMESAYAGQKRKSSDVHFDDDDSDDDDRPRQRRRSNSSTPIPILEKPTGRGLMVARSSQSLTIPGSDPFKMPSGAQPQKGPSARALKRRLVRMRDEKEVVIRKYYNMGSSFSDPITSTMYALASEMGREDNDLLWFCIVGVSSMEMYGRSSAGLAAPVRGKDSVVSGWLGVRGARIRQVLRDEVRRLNPPDVLGVASPEEKGIIPTTARSPEDNGIRLSPEPKFLLIRHWSLYDSMLHSPYLFSRLRTWSESGIKRLHKLLAKMGVSLVQCKQSYVHMDMTLKRDLRQKLLKYAALYNLEEMVPSLETDGKDRAGAKDGWGFVRSWGWKATLSAQDVVVILGALLEIGKDRERQDKQPYYGSSHADEDVDGQARTDEWITRFWQAYDALEDVDALKAGLSTAQYLHRAIYRTGTSLINKRQIKHLRAFRLCVVKDGADVELFTHPAALTKLALWIGEALTEQERDQLGKLSHSGRGTPLVAASLDEKRGVYTVVGTGGGGGPDTAFLNREAARKRAEQRERKAATREVKRLAKAKACEEKRAARREAAAKKKAEKAKEEGGQEDNGDGDEELDTESEGSESESESEDEDEDDMEASQERGYGLNKFGAAFQEVIAETNARVRVDSFEHSVVEVKKEDLGSFLETLSMKAVIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9N4</accession>
    <name>A0ABR3Z9N4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNA helicase</fullName>
            <ecNumber evidence="4">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">SUV3</name>
        <name evidence="14" type="ORF">Cpir12675_002575</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000052">
        <property type="protein sequence ID" value="KAL1896927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17913">
        <property type="entry name" value="DEXQc_Suv3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18805">
        <property type="entry name" value="SF2_C_suv3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055206">
        <property type="entry name" value="DEXQc_SUV3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022192">
        <property type="entry name" value="SUV3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041082">
        <property type="entry name" value="Suv3_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044774">
        <property type="entry name" value="Suv3_DEXQc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22527">
        <property type="entry name" value="DEXQc_Suv3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12513">
        <property type="entry name" value="SUV3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18147">
        <property type="entry name" value="Suv3_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="162"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="325"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1896927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="700" mass="79479" checksum="D0D8799F80875057" modified="2025-10-08" version="1">MQKFKLHGTYKVPEEEVQFAIKNGEVPAIRPKPKSKHQLFHDVVLVMFARLAPGNESLEVVRSKYESFGIKTLAQYINERGLFRRAIDQSLSSSASGHRSKGDNPLYFSLRQKFIKEGYKGLQIALSYAFQMFLSRHHFSESVTAHQSKLADLRFPWEWFPATRAMQRTVHLHVGPTNSGKTYHALKALENAKSGIYCGPLRLLAHEIYSRLEAKGKPCALMTGEEQRIPQNVDNYYISCTVEMAPLGKPVDVAVIDEIQMISDTDRGSGWTTAFMGLQAKELHLCGEERTVDIIKSLCESIGDKYVVHRYNRLTPLEAASMPLDKQNNFSDLQKGDCIVAFSRMDLHNLKNTIEEATGKRCAIIYGSLPPEVRAQQAAQFNDPDNDYDFLVASDAIGMGLNLEIKRVIFHTTTKNDGYSWRQLSVSELRQIGGRAGRFKTARQGMINDDSAENKVGIVTALEEDDLKVVQANLWKDAPPIKEVSVFPPVSVIEQFSQYFPVNTPLDFVLLRLNELASLSSRFRIYIKDELFKVASIIQPFPMSIHDRCVLLTAPAYLRDPQMHKVLQGVARCISEMKNGHLLQMPEILISTLDINSDEVPESSQADYLRALESLHGSVVLYLWVSYRFPTVFTSQKLAFELRRRVQAQINKALEIMKPKDQEFLERRRMNQRTLARIREQETSSLVDKVELEEIESVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAX2</accession>
    <name>A0ABR3ZAX2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD dependent epimerase/dehydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000039">
        <property type="protein sequence ID" value="KAL1897811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040632">
        <property type="entry name" value="Sulfotransfer_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978:SF4">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17784">
        <property type="entry name" value="Sulfotransfer_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="299" mass="33911" checksum="F9A482D150D0F89F" modified="2025-10-08" version="1">MSTRPTNGGAAEKDASPRVVPMRVIVCSLMRTGTLSMRAALRELGIHDVYHMQTLGKSAEEDIPLWTRAIEAKYHGKGKFTRQDWDELLGGHQAVTDIPASFFAVELAAAYPEAKIVILTRDADKWYESCLSSIHSAFSSISLLDKLLIITLDPTLRTFAMFMNKVNTVCQGFTWPEKEKALAFYDRYYTDFRTKISNDNGRVLEFSVKDGWGPLCKHLGLSVPRHVVDGKEVQKPFPRLNDSSSYGKAAVIKMRAMRKRVFWRVFGFFQTALLVGLLGYHFRDFILPRTGMLTNMWKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAY0</accession>
    <name>A0ABR3ZAY0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">mitogen-activated protein kinase kinase kinase</fullName>
            <ecNumber evidence="2">2.7.11.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">STE11</name>
        <name evidence="15" type="ORF">Cpir12675_002478</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.25"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.25" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000048">
        <property type="protein sequence ID" value="KAL1897221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004709">
        <property type="term" value="F:MAP kinase kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd09534">
        <property type="entry name" value="SAM_Ste11_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029458">
        <property type="entry name" value="Ras-bd_By2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11584:SF369">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 19-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11584">
        <property type="entry name" value="SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14847">
        <property type="entry name" value="Ras_bdg_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01304">
        <property type="entry name" value="Ras_bdg_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50200">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM" evidence="13">
        <location>
            <begin position="67"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-associating" evidence="14">
        <location>
            <begin position="263"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="635"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="166"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="412"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="188"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="214"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="664"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1897221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="908" mass="100435" checksum="642509C197D5E89F" modified="2025-10-08" version="1">MAMLTQKAFGSSLGPSGASMVPQMTTAPISATRHQVTMKQPSSHAFVISPTNSEFSDCEGPDSVKNWDENRVCEYLHSVKCGDYERLFRHNHINGENLLEMDKDVLKEIGVEKVGDRVRLFLSIKKLRLKTYANQKKRTRDSLGYIDSPQLLQSVGSKLVNNARSQAISSNGNNSSSGPGRRYSRSYQDSLAPSDAANSISRSESPSQTDLRPSMSRRYGGGNSSYSGARSPPEPNKSARLANTHIRNKSSFDGSLMAGLPQGQDVIRVISNGGVTKVVKISDCNTCEDVMRVTLRKFSLREDYERNYCFWVLNGLEPDPSQCRRLGDTELWRIIRDQTRPERNRLILRRVSASEPGEAELDRAAAIAFQETQQTHMRALETHDNKRSQLKVQKLLGENWNEGLQRPLAHTRYASSSPKGPDAGFDTDSSVPSSMRRKSSESQLRPFGGLRPPSELITSDLTSYFPDHAREDIDRTARLSVRRSTRLSRVNHRLSVASTMSFASSIQDAPPIPTIADSWLSMNGGKPRIASRLGNFRDSVASSVLEPLVEEAGAGDRKSFLEYPPGTVEPTVINVTDPDGHTMMRRSYYSDETATIGSGSGSIQELQEALNEDGEEMDEELQSFLSGESWDDNKWMKGALVGKGSFGSVYLALHAITGELLAVKQVQAPSGTQSQTDQRKKSMIDALKREISLLRDLKHPNIVQYLGCGTSAEYLNIFLEYVPGGSVQTMLNSYGALPEPLVRSFVRQILTGLEYLHERDIIHRDIKGANILVDNKGTIKISDFGISKKLEASNILNGTNNAKNRPSLQGSVFWMAPEVVRQTSYTRKADIWSLGCLVVEMMTGTHPFPDCTQLQAIFKIGGAKATPTIPEAASVEAKEFLGKTFEIDHNLRPNADELMLSKFLVPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBI8</accession>
    <name>A0ABR3ZBI8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HOG (High osmolarity glycerol) pathway protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">NBP2</name>
        <name evidence="5" type="ORF">Cpir12675_002132</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000038">
        <property type="protein sequence ID" value="KAL1898043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="313"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="71"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="131"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="181"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="390"/>
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</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
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            <dbReference type="PubMed" id="38831329"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
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                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
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                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
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                <person name="Duong T.A."/>
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                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
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            <dbReference type="PubMed" id="38831329"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 6">CMW 12675</strain>
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        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        </source>
    </evidence>
    <sequence length="2177" mass="240598" checksum="2A2F92C3D9F8DB68" modified="2025-10-08" version="1">MELPHSLHRQLAQSQTNHLSISNRVRFVTMESSTPNPSTEKSHDPATPKKVPAKTNVTPKSAPAAAGGTRGRPPVRRIDTLPPSLLTDFFLGRPSPARRAALKARRESMDAIKAELRQEMRAEAVRKVQPPGGVRDRVRKWQRSNAAAMAAGDPQVPPSEPGDVAFESDDHSVTEEDRIRIRSQPQKRTSTSRRPSAQKSPITPKRAITPKAKRGSQPPDLNHGSRSLPSKINQPPKKRVVSDDHWMKIKLKKKPSHRRKSPNTTQRIPKDFAHKTMNPPAVSKVRDWVNRVEIPDASPTSPPMSPKSRSVYRNHNHSQSMPNAINKNAASHDGTESESGSESESESTSSDNQDDHHNNDARLTPSRPLMFDDESVHVKPLRMNLKKTPAPSAVSVPDDDGIRVRGSEIHNDVTSTRHSESNDGIRVIPSEPFGDDGIRVTPSEPIGGDGIRVAASEPGGSVRVRPWTIDDDGIRVRGSELDDDGIRVCPVLDPLDNDDQITSLQEAEDALSSMLGTSIIDRNHNDQSRNNARNISKSKPPNSKSLASGTAKLPVRENPHKTNRTNGKVAGKSTKSRSGRRRTRSLGPPATRSVRTCSFSTGSSVSESEDGLSEIPVGNSAFSVLELPLSEEAHKPRNRQSQPLPARPPMFRDVPNVFKKMMSEGKKILQEVHEPAKTIPAKQSALVRIENWLSGTFEPKIENETAKAPIKKAIEKEWAQESQIRKSSVEYHPGKHEHDDAENPTADFKAEAFMAIKKEDDDKEKDKRREMETARKEKEREQEKTPKKPTPLNDTVATPTSPDAAPKVSKITPADSRPPDEKEKKPAGGLQRKPTGLGRPKSASKSPTSKKPLKDAFRDAFRGESIGHNLPPATYQSQEDRAYEVEVTAHDESLDDEWQSQLRPHTSPTESDFSYDSRIPYETRYADSIITDSDMTPAPLRRRAPPTNDNPSLIVTSDEAVHHDPDSSHTTDLSNATPAQTNLTQATSVGNEQSKSQREAGARRQPSYISSIDTVNRKPSVLSVARPSNRNPSNISGTCSFDENSSFLSDRNTLNRSPSFVSGPDTIDRNHSFASGTGSQKRRASRASSARRSSHKHGSHYSHRTNSSSGLKRKLTKHSDLVSVLSMPDEEDMVSTVTDTQSRTSRRTGSQSTIREKRTSGSVQGPIAALLRDFADEETSYARELKSLVDGVVPVLLKEVLHWDGKAPLFGDPSVKGGIFSKSVVDMGICLEKMRNSHKKAPLMDIYQLFAWLERVHPVYDSYLDAWRLGFHDIVVNLAPLIDTLDDTDSLLDAMPRNDEGDLVDDDGTRLDVAHFLKRPLQRIKRMVKFLKGVTKALPSATTTALLESFNQLQDKARRRYNEEIARITDKDAIETDTSQCLNLQTMEKMESVTIDSLRQVNAKDVFSLTLWHSNGQRLECQAELVHRDRPQVYSDPGDLLIRKTDGEKETWLLFAPITMDYVSARQDEFGIMVMIRGPIAHPLPGEGQEWYELLHLRTEDELQIEDWISIFNPSPIPAFNRRRVVPGSISVAPPIASPQLSTIMEASTEISSVSEISTPGKDIIVKVKSRQGRSPHTSEVGKHETSQSDEQKPRNSSSSPEPEAHSSGSDVTVKNESSDDKPPAPPVHRTLSKSSTPVLAAPEPLRRGVERRGSSPLKHEYLPSDVSSEASGSVDDQSEKTYSDPEDDESIHSGSESRTGSEDESYTESESSSDEIDIIDMPETELGISIRDEDQQREFRAATASVMTYDTITPSHSASQVGSRDEYHKGEEEEAEQVAEIQDHKFISKVSQWSDKKAIWKDLEAENCWVVVHAGCLEVHHMGVEDIKVAEPLVALDLTPLILLRQSTFIDLEIRAETLDTGSIFARHGANLRFRCQNTAECYDLYAAVHNARLQNERYTRKQDELRIKSFGQSAYPMSAGAGDGANNRHEAANKGWFGRRNSYRASTRAPTQSQALSQSQDGASTTPSSNASAASSFLRRLTGGNLSFNLAKSSVNHHANGGPASLYSADSSRGGPGLRAPSLSMASQSTSKKMTLDSDAIRIRLHLLITQSKWEDWGNCMLTISRPPPGKHMSLRRYHGLEKRVTVSTIPKKNSGEKPAIIIDAVLGSGCFSPMGNRGVVCGIWEEVKDEKGVVGNIPQNGNAAGNITKWCFQCKNGVEAQWVLRNLHQEVELF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCD8</accession>
    <name>A0ABR3ZCD8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Tubulin beta chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">TUB2</name>
        <name evidence="16" type="ORF">Cpir12675_001971</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 12">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000034">
        <property type="protein sequence ID" value="KAL1898345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02187">
        <property type="entry name" value="beta_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013838">
        <property type="entry name" value="Beta-tubulin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002453">
        <property type="entry name" value="Beta_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01163">
        <property type="entry name" value="BETATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00228">
        <property type="entry name" value="TUBULIN_B_AUTOREG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9 12" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 12" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="14">
        <location>
            <begin position="47"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="15">
        <location>
            <begin position="246"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="427"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1898345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="447" mass="49917" checksum="4D4C44941513B2B2" modified="2025-10-08" version="1">MREIVHLQTGQCGNQIGAAFWQTISGEHGLDSNGVYNGTSELQLERMNVYFNEASGNKYVPRAVLVDLEPGTMDAVRAGPFGQLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDQVLDVVRREAEGCDSLQGFQITHSLGGGTGAGMGTLLISKIREEFPDRMMATFSVVPSPKVSDTVVEPYNATLSIHQLVENSDETFCIDNEALYDICMRTLKLSNPSYGDLNHLVSAVMSGVTTCLRFPGQLNSDLRKLAVNMVPFPRLHFFMVGFAPLTSRGAHSFRAVSVPELTQQMFDPKNMMAASDFRNGRYLTCSAIFRGKVAMKEVEDQMRNVQNKNSSYFVEWIPNNVQTALCSIPPRGLKMSSTFVGNSTAIQELFKRIGEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDAGIDEEEEEYEEEAPLEEDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDI9</accession>
    <name>A0ABR3ZDI9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Splicing factor YJU2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">cwf16</name>
        <name evidence="10" type="ORF">Cpir12675_001934</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CWC16 family. YJU2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000033">
        <property type="protein sequence ID" value="KAL1898389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03226">
        <property type="entry name" value="YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007590">
        <property type="entry name" value="Saf4/Yju2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043701">
        <property type="entry name" value="Yju2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111">
        <property type="entry name" value="SPLICING FACTOR YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111:SF1">
        <property type="entry name" value="SPLICING FACTOR YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04502">
        <property type="entry name" value="Saf4_Yju2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="113"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="235"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="134"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="248"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1898389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="316" mass="35737" checksum="264B21B758463E57" modified="2025-10-08" version="1">MSERKVLTKYYPWDFDPSDISKRRGPKATGPKVQTVRLMAPFAMRCTSCGEFIYRGRKFNSRKVTPPEERYLGIQIYLFHIKCTRCSSEIIFRTDPKNNNYAMVSGAVRNQEPWWNKGEEEETEDQRLDRLEREEAEAEGDEERDAMADLEAKNVDAQREMAAADALDAIRHRNARIQIAAKDGVDFSAAIMQTVDEEKERQDREDEEAARMAFAVAKEKQLLQDLGMEEMDEIVEEDEHPTMSVSKPEAAIPSLPSSSSSATPTPVSATQSAKSADNSLANRIPLVDPAPAFKRTIKKKKDYSAMLGIKKKKPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDL7</accession>
    <name>A0ABR3ZDL7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mitotic spindle checkpoint protein Bub3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">BUB3</name>
        <name evidence="4" type="ORF">Cpir12675_001721</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000029">
        <property type="protein sequence ID" value="KAL1898718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10971">
        <property type="entry name" value="MRNA EXPORT FACTOR AND BUB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="101"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="264"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="357" mass="38499" checksum="7175E7D860C95521" modified="2025-10-08" version="1">MAPSAQYDLTTPPTDAISALAFAPSNPARLLASSWDRNVYVYDIHGENEAGQKCGTLLRKFEHRAPVLWVCFGKDDNEAFSAGLDWRVLRLDLATGEQSVVSTHSAPVRSVAYSHEFSILVSASWDQTLHFHDVKSSSSNPISVSLPGKPHALSVSPTKVVVAMTSRLVSIYDLSTVAETFSANDSSPITIVPWQQRESSLKFLTRAVACMPNDAGYATSSIEGRVSVEWFDDSAESQARKYAFKCHRQSAPDAEGGGDIVYPVNALAFHPVYGTFASAGGDGNVALWDAEAKRRMRQYPKFSNNVAAVAFSNDGKHMAVGVCPGFQDGQEDYVAAGQVSIVIKELGETEAKGKGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFJ0</accession>
    <name>A0ABR3ZFJ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000028">
        <property type="protein sequence ID" value="KAL1898962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="298" mass="33855" checksum="AF1D36DCE27AB646" modified="2025-10-08" version="1">MVSEPRQVLGTLQPFSGNYEEYEDWRLDAENKLRTEVVRRLMDSENCKPSDVLNHFDHLYIPANTSVWAHQKLHLPQGKVPIRRFLPKFEARLTDARGHDWPDESKILTLTGVLDKRLFALMSLRCNGKETFAEFCQLDLSCEGNDGASRYISGLLNDPVASGPSTRAGDPMDLSHTYESQQGDEIDRRRRRQANQSASGIPTHDAQGRPYPTDSELRGRRAKWVTREELSRRKALQACLRCARPRCRTSRCPLSPPVNPAKQPARSNAAQQEKLIPALAMDDIVDDWLDFPDQCSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFK9</accession>
    <name>A0ABR3ZFK9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">F-box protein: endocytic membrane traffic, recycling ReCYcling 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RCY1</name>
        <name evidence="3" type="ORF">Cpir12675_001583</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000026">
        <property type="protein sequence ID" value="KAL1899027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009976">
        <property type="entry name" value="Sec10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048627">
        <property type="entry name" value="Sec10_HB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12100:SF1">
        <property type="entry name" value="RECYCLIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12100">
        <property type="entry name" value="SEC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07393">
        <property type="entry name" value="Sec10_HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="27"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="428"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="549"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="555"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="573"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="975" mass="107880" checksum="14EEAED6A134C47C" modified="2025-10-08" version="1">MYGRKSLAAPPLGPPSFVNAMKNIDMTDSRPLLPAEITVKILNYLDIPDLMHCACASRRMWEMVYDDSRWVARLKSMGCWDEAAARRRFDQHVQRRREAAAAAARQRQAAAVRPDGSTTLFDQAVEENNLRVAQAAAAARPLGDLDGFKTLSIASGQLQPSTQAVSTEDPAQPAGNPASDPMSILNVIKNAQSIRGHAREEFGKIYGALSPFYNDLVRSKSHTDPIIFKVFRDPERQAQMLANLRAFARCDWSAGAVEREERVLAMIGIFESAVLREFEQGYEFWDVDGRMKRYATVLHLLNGGSAGRTLFVEKHPIFSDPELLAKDWLECLSKAHDDIMLLGPVHQFFQTLLSKINIQAGVIERIFPEPQSVFWMLVDRCCDELVNDYITPLFDDAHGRNIEVYLKAVSAIFEQCIVFFQSLRVPGSVSSDAPVSIKDSSGDSPDPNEKEIAEKAAALTLKKAQEMTWRLFEPHLFTYLQEELDFFTGYADAKVAAWEKNLSEQNANVESFFMSSFSNRQAAKKDFLSSFKTVVMMPVTALPSFNFSSSLKTAEPSESRSTDRTTKSDSSTGPNLTEPTSSSDAINASTMPSLPAQAPTDELAAKAALMASRLEGIKSLFSMELAIDLIHHAKVSIGRAAVFIPLGDQAGGEAREQCEAIFAALLRSLGTQHMNAGFQQAIEHLASYNPREAAASSRSRGTRPVPTSGPSATGVAPLAMFIELVNVGDLISQMIDVFYEQQLTSTNIVDKRDFLDPAAKAKKKFEQMLDENVAAILNKGIDVLMNEVEYLQATTQLPTDYNPPSESTVPAKRGTLSGVELDIGPTPTAQRIVDLVSSHTNMLVGTTDKAMLDVFNGEVGLRLFTSICKHLKRQRISTAGAIKLIADMNAYWAYIRSLKNPDLQAYFGALRELSQIYLIDGKHAKEMAMVIADTDRFGGVFRAEEVYEYAQRRADWFVVKKSVEHAMYGLDCLLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG53</accession>
    <name>A0ABR3ZG53_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Nitrogen permease regulator 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4 5">Required for meiotic nuclear division protein 11</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">npr3</name>
        <name evidence="8" type="ORF">Cpir12675_001411</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">Mediates inactivation of the TORC1 complex in response to amino acid starvation. Required for meiotic nuclear division.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Vacuole membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the NPR3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000022">
        <property type="protein sequence ID" value="KAL1899375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056603">
        <property type="entry name" value="HTH_NPRL3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005365">
        <property type="entry name" value="Npr3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13153">
        <property type="entry name" value="CGTHBA PROTEIN -14 GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13153:SF5">
        <property type="entry name" value="GATOR COMPLEX PROTEIN NPRL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24064">
        <property type="entry name" value="HTH_NPRL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03666">
        <property type="entry name" value="NPR3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0469">Meiosis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="GATOR1 complex protein NPRL3 C-terminal HTH" evidence="7">
        <location>
            <begin position="785"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="145"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="620"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="739"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="155"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="165"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="178"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="207"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="238"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="620"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU368069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1899375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="851" mass="95152" checksum="4CA719E2E3C0A6EB" modified="2025-10-08" version="1">MSFPVLPNTSTLIAVALVMNRSHDDGPSFVFHYPPKVSPFDDNEEKATPDDLIIERLSQPEEEALGIAGYQKSTSLQWSRDDVLQPGNADSMPWETFVGLPTRDLASILTPKRSFHKKLFHLSLDPIHCIACPMHVPEGGIWRRTRKKKNKGKSVASTNATNMTNKKEREKEKEESVSPKTTVENAQSVPVARLDEAVSKLRGTIVTDDDDEEDSQAELGETGGGHDEEAGENQAEQTARDSEHHEPVKKKDKEKDAEKEKEKEKDRPQRKPSPMTMFNLVFFLNPKKHETNELVENIYRHVLKKTTRIFKYSQQQSDFVWKESKRILATKDKGREMKASMNDLWLEIMRTSSLAAAIRELYTAVSNNRIATLQLETAGGTLSPSVQIPFPNSISQLPAEGAIQQQGIWLTTAHMTISDDNNSDEPEMVDRTFGLLLLGSDKKIIAELESDPDPTTVAMVEFVRLASQPNNTFQQMADTHKLTLSQVRKFASHFIFWRRGIAIPPLFARDVYIASPNLCPSRLPRASQEWQRQFPMALPLPVFLSEISTAPRQWKYWSPAKAQRPEYMKMLAWLMRGGWVTQLCTFAYVVVWPEIIYEVRYAHEAAKLRTARELYERSEAAANASSPSTSASSSPLSSSPDQSRGSGFHHYSHSHHPPGSGGLGDISPGPVSPTIERRPQIGRPIKGAAAAVVAASISRAASHHSAASSATALARSNHSTMADQIAEHARLARQAAAAKRKAAEKQTAHARKTPPMATPHPSTNNAPHLACIEPHIILDPRRATGNEAEYLDAIKARFASETTADSWQRFAKYFNGQYALERISLQEGMRRKDVFNRIGEMGEYLLCVRHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG98</accession>
    <name>A0ABR3ZG98_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleoporin Nup159/Nup146 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_001284</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000019">
        <property type="protein sequence ID" value="KAL1899701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026054">
        <property type="entry name" value="Nucleoporin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039462">
        <property type="entry name" value="Nup159/Nup146_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23193">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23193:SF23">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16755">
        <property type="entry name" value="Beta-prop_NUP159_NUP214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117289">
        <property type="entry name" value="Nucleoporin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin Nup159/Nup146 N-terminal" evidence="5">
        <location>
            <begin position="41"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="622"/>
            <end position="1332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="625"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="646"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="704"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="742"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="775"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="808"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="836"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="898"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="984"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1004"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1021"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1048"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1096"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1115"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1148"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1180"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1229"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1271"/>
            <end position="1283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1293"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1321"/>
            <end position="1331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1792" mass="187819" checksum="E997257C5F9372FE" modified="2025-10-08" version="1">MASSTVAMGDELEIIQTELLGFKSLAGDAKVQLTSAWFDLPPNTASLLTIAHRKCLVAGAGPDAIIIVRTDTVRKAFESPSNDDSEARPVEPLAKIPVSAPISHLAFTSDEQYLLVASQHSSSVAVYETASLLGGGQSSAFELSINDVAVRILCPNIASEKAELCAVVTENGALHMLNLKSRSISSALVSEVSCIAWSTKGKQLVAGKVNGTVQQMTPDGDIKAEIPCPDGFHGVHVSSIQWLENHLFVAIYMTMNENPPTSTYYVITRQPPSSYNFRKLSDPVDPFGSEKAPHHSILRLKDFPPNLQNVLVVSSTESPDIGILTRSKTPLSTDFASDSITGVFTMTEMLDDTRRAGLPMDANCNNSIPIGMALDLSARDTVYKPIPSEEIDESPGPVPAVWVLTNEGVLVGWWLIYNESIKEGTTYPNMAALLPDLEEPASLQSATPATPATSAPPALAAPAALSSTPSAFGAPSAFGNASTTSAFGSASALGSKASPWGASDTASASPSKFGTSGFGNAPVPSASPAFGQPSSIGAGQSVISAKPLPWGSSSNVASSAPEFGQSGFASYGGTKSAFGAPSASTSSPLGSSAKSGGFSSFASTGGGFSSFGGAGGSSGESIFGNTSGTAPSPFNSTSNTDTAFKSTGSSGFGSSRPFKLQSSFQPQKTDGDEDATPDTKQSQGGSLFGTGFGAALDTSNSQSKDQDMDAAETTRAKTPSKSIFSAAAAITTPEAKGHFGTASGSFGSTRIPSQSIFGQPSSVNTQTPPKVEPPATSQSVFGSSSTPNATPRTAQESTTPATATKPIFGQSSSGFGQSSTTPSQTKSIFGTPKPAQESTTPATTGKSIFGQPSIGFGQPSATPNQKKCIFGDPKSAQEPSTPTAPASIFGQPSRGFGQPSSTPSQTKSIFGNPTPSQESTTPMKSGSVFGQPSKIPIPGATRTSIFGTPSSSSPPAQPATNVFAKSIDKSKTIFGSSTALGDNGKADEEAWKKDSPDSDKNGEEEFEEEEDQEEEHHQDGESQEEPFDEEDSNSEESTTPASKEKSSKPTLSSFKASESSQKGASSIFDSTTPAKTTMFFGKATTPPTKSKIFGQTGESSTPVGKSMSTTLAKNPFAASTTPTTTPAPSRFSFMSSTSAPVPPESTSKKSYTAGDSSSSSASKKGVSDDDSTFLKPSLPKSTAKSTEKSTSVLEDAPLPPDPRLLTKKPTGRVGGIGKKSNFRKPPPPESEDESEEQECDDEEVSGPHDGNDLESDLEFDGSVVHVSKEISPSSSGRTHSSFSGLNGPFTLVSKPSTSDKTSLFSESLGKPSAIFPPPTQTSPRSPSPMRTAVPPRIMRAEGTRSVSAPGLPSNIAGCGTVGKAFGSSILGSKDSQIEENSFLSQQRKAKAKKDADEAQPLVDDEDDEVQKLLASELQPTLEIDQLMAHTDVAPPAHDSIPAQVEAVYRDINSMVDTIGLNARSVMQFVLGHSQNNGVQRQKEDLEIPDDWVLCNLMDLTDIIEIDLANDLKQSCVSNPEQKKTVCNDLMRSMSRLRSKQQDLQVILARLDPNQAEMYQNLPLSPEQAAQQNELRREFAKFTQKLADVEEALTLLKTRIATTSQASGKGKGASAQVPTVEAVMRTIGKMTTMAEKRSGDVDVLETQMRQLRIASASATPIRDLVLAANAGPSTPRTPQSYSKRASLFSPDRSMAGSASTVIFSPATPRAGYSSLLANSNGPFRASVSMTPVRDLALTPGAMASPVRRKLSSFSKEEKVQLMSKRARKKAVLGKLKAQVQEKGVTVWEMETVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH14</accession>
    <name>A0ABR3ZH14_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription factor 25</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000017">
        <property type="protein sequence ID" value="KAL1899995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006994">
        <property type="entry name" value="TCF25/Rqc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22684">
        <property type="entry name" value="NULP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22684:SF0">
        <property type="entry name" value="RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT TCF25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04910">
        <property type="entry name" value="Tcf25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="704"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="704"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="724" mass="81035" checksum="655A2307011034B7" modified="2025-10-08" version="1">MSSRQLRKLREKQDLAALAQREAEGILNKDDEESDSGAEDYVVKPQKSLFAALGDLDDDDNDDSDDDDGNEPETGDDARIKINAALSPQTCPDVAPKKKKNRGKTKRKGKKGGISNDKATKNTTLGVPVNNKDRDGDEIDRILRELNMKDSAFAAPGSRNARTPTEIHKELFSVNSKNLKERTEMIAVFGRDVINATESVNTQPPQVRSNGTMTLEDVLRQYAKGKLPDITLKRNIFIDGKESWPKASAEGLMMERVGKQETEACTEYKFVGNSAFNKIKKIFYRTARLGDLGSIIGGIHPFRKFPSTISYHVMYLLQCYLIAKDHDKNHAIAADLTQRALFTFGRVSLSSFRKDVETGAARLDFAHPENRWFFLAGYRNIRALVQKGAYRTAFEWAKLLLALQPNQDVYGMNHVIHMLAVRTHQVGWLEAFLGWYKDNETVAYAPEHAYYRHSLVPGLLQQGKTAEAREVLRGNVENMPWLYCRLFQALEIDPAPAIWGVQPPTDVDDLFTEIYVAYGKDLWASPEVKSLLRSTALEAKRLDVLETTRVTADLRTTRFIYLENNAELMSRLPNGSLAVEPNYDFDPLPPPQAENIFTDPEDSWPWDEVMASHGDNMATLGLEGASLQNLGGVGDIARQLLGGVFGMGGTAGRPRTDEEAIAALLEADELETRGHDEFYDEFGEEDMHARDAELPTRPYQVTIEEVEEEEEADEPVGSGAGRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH63</accession>
    <name>A0ABR3ZH63_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type I protein arginine N-methyltransferase Rmt1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RMT1</name>
        <name evidence="2" type="ORF">Cpir12675_001436</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRM112 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000022">
        <property type="protein sequence ID" value="KAL1899400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039127">
        <property type="entry name" value="Trm112"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005651">
        <property type="entry name" value="Trm112-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12773:SF0">
        <property type="entry name" value="MULTIFUNCTIONAL METHYLTRANSFERASE SUBUNIT TRM112-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12773">
        <property type="entry name" value="UPF0315 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03966">
        <property type="entry name" value="Trm112p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="127" mass="14016" checksum="78FC2D909CBEFADC" modified="2025-10-08" version="1">MKVLSLNFLCCAAKACKSSNKGFPLHPKDAELVQDDIEVNATLLLNLLPRIGWEALRTTSTELGFPDLPAEVPTPEQLQSDSKMMEDLHNLLVNTQMVAGKLVCENCNHEYAVREGIATFLLPSHLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH67</accession>
    <name>A0ABR3ZH67_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001251</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000018">
        <property type="protein sequence ID" value="KAL1899750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF10">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="148"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="726"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="763"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="771"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="815"/>
            <end position="827"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1051" mass="116501" checksum="A20D6629FC19BA68" modified="2025-10-08" version="1">MRLLNTETLLLRDFKTSNLPPYAVLSHIWTKSEITYNDMKSSRKDDDITTPEDTDYSDSDADSDVGGAPSAVPSFRPSLGRRMSRQSTNQRRSISRARSLHRSGAYSDTEPDSEQEAPDISTPHTGASSEARSEFSGTDGSPSPELYKIRRALQAAAREKIKWLWVDSCCVNEKSQSDKYEAVTNAWNLFANSAVCFVYLMDFTMPDDLDDMDQAITSDEEDDDSEDGGAGLRRDRRSVPNPPTNWRKAFRCSQWFRRAWTLPELLAPRRIIFMDRNWDNISAAVPHPDVLNMLISQSTGIPQAVLQRRVSLDSVNVATKMTWMADRRSSRPEDISYALAGLFNVHIDVRYGEGAKRAFQRLQHAILETSVDESILLWDSWRTYKNERTGLLADRPEQFLQSDDLAPAPAPLMPHRATWSITNRGLKASLFMTPHASPSTVGNFRRVWLNMFRRDSKEFMCFFVQQVGDADEYARVGPIVPVATNFIAFAKEREQHTIVVAHTVDDEAGSVGSPSAGLSFRSNGSSSIGGAGAPITGTRPHVRFMLDSGVRRVVPHTPHHKPSWTVKSTVAECLSPIPHEDYHVAIVQFELKTPSHAAKLEGKFLVVACLRLLPEVGRWQCALRIDEAEDYTNEMPGMGSTRALRDAPSASPRTMAQLDVGIEGTREIRAEVIEWIEWHESAFEVTITCPAPLPTAHPSVAADRDRIFRGTTPLNLNTGVGMGINSIPGSARSRQRFAGPPPVSGYPPLSAASQRIRMGRSMSVDHGTSPYIPPTGPLPPPGSSLLRRDREMSPPPSLRGGIAARKRDSWGGPPIAAPPTPLSPPRRPTTTRPSIRRPPSRYGHAREEYSPEYGPGPGVGAGSYEKTPLFPGSRGRRDSSNYIESMFGSEGPRTRTDPGRQSWSDRFWDRPVIDESITNDDHPIAPPSRRGTWTPAPGHSNFGLMHNHGRGHSYSHSQSFQGCYDRDRDLPVRHHDAPPAAPMLSPGQAPMGGMSSGVPSIPPPHQSAMSGRVGRLGSFDEGPWGENLRSPTIVEGAMEQPFRNDYQYYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHR2</accession>
    <name>A0ABR3ZHR2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diacylglycerol kinase</fullName>
            <ecNumber evidence="3">2.7.1.174</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">DGK1</name>
        <name evidence="3" type="ORF">Cpir12675_001170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.174" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000017">
        <property type="protein sequence ID" value="KAL1899949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141035">
        <property type="term" value="F:CTP-dependent diacylglycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037997">
        <property type="entry name" value="Dgk1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31303">
        <property type="entry name" value="CTP-DEPENDENT DIACYLGLYCEROL KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31303:SF1">
        <property type="entry name" value="CTP-DEPENDENT DIACYLGLYCEROL KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="543"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="585"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="610"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="643"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="388"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="449"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="754" mass="81017" checksum="92A32A5C996145AD" modified="2025-10-08" version="1">MPVASVPQGALPAAKPVVAEVASRQRSSPSQSQAQGLNQDADSKSSDSDGQQRANQKRARGSQAHASQDKSQTSWSPAISASATGAEYLLSSDKPRARSPAGSTPAEIPVDTNSLVASQSLKLHPQCRDSPPLAPPIPQVIVQPAEVADTSTSRVSTGLPPPSSSLALSISPLASPNALPTSLSFASEAALSLSVETPPPPPLETPESLEFSLSPLFLPLPPPSPQSSSFWSLFFSLPDITIHHRPCCLGVFSLSPTAQGPALPLFSSRLLAFCWSSPSPPPQSSPHHHHHRRRRFRRTMAASTRSQQRASKSSDYDSPSTPTKQTFSLVDMDASSVNYSGPVTRSVARRRTTSRPASSVAPATPSTRNSASTRCHQPQPSASIPEQSPSSTDSSIDSIDDFDHNDNNNLGRDNIHDTDDLDTASSNDSPLGSKTNSSLPLKNLSTVDSSSSSAATFQNQQQNNSQANMRHPKKSLPTLLAPSSPSAWNWDLNRCPSPLGLIPIHRQWRAFIHKHEVPRKALHVSIGFFSLWLYVSGTQTTSVTPWLMGALIPITVVDVLRHNVPSFNAFYVRILGALMRESEYSGYNGVIFYLLGAWTALYFFPKDVGLLGVMLLSWCDTAASTFGRLYGRYTPKVRRGKSLAGSLAAMLTGIATALYFWGYLAPRVSFMPGDEHFPFMFTGELHLPTPVASLLSLTPEQATVSGSAALSIVSVFTGFIASMSEVVDLFGWDDNLTIPVLSSLGVWGFLKIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI00</accession>
    <name>A0ABR3ZI00_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lysophospholipase</fullName>
            <ecNumber evidence="6">3.1.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_001129</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15177"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16870"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:58168"/>
            <dbReference type="EC" id="3.1.1.5"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the lysophospholipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.5" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00147">
        <property type="entry name" value="cPLA2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002642">
        <property type="entry name" value="LysoPLipase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10728">
        <property type="entry name" value="CYTOSOLIC PHOSPHOLIPASE A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10728:SF40">
        <property type="entry name" value="PATATIN FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01735">
        <property type="entry name" value="PLA2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00022">
        <property type="entry name" value="PLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51210">
        <property type="entry name" value="PLA2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5 6" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4 5 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLA2c" evidence="7">
        <location>
            <begin position="206"/>
            <end position="821"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="830" mass="91498" checksum="ED20A8639098722A" modified="2025-10-08" version="1">MPRVSPLVRRALRTRRLQPLVAHPYAPVSLRLYSGRGCAGSAPGRIRSQKTLSGSFYRELFTSSKALGSPQSSQTHRSTPASTTAVVTSALLFIWMLYPTDEFDQLKPSVGSSATTESASEGPGLPLPSLPLDTAWANFASNFEAFSDSMDIEWTLLTDKIVDLILPEWSRLVPAYFRKLQRELSMAPGSLADEIWTDAHDASISPEIRYAAKVRVSNELCEEEREFVSRRRKMAAVALARYLDLEETDVNPDDVPTIAMCGSGGGLRALVAGAGSLLAAEKDGLLDCVMYTAGVSGSCWLQAIFNSSLSSGKANKVLDHLKARLGVHIAYPPVALDAISSAPTSKYLLEGLVEKLKGDPNAQFGLVDIYGILLSSRLLVPKSHLGINQENFKMSNQQKYIRYGQAPMPIYTAVRHEIPKLDDDNGNRASTEHEKAVAKKEAWFQWFEITPYEFFCEEFSAGIPTWALGRRFNKGLDVPQEDGFHLPEIRMPLLMGVFGSAFCATLNHYYREIQPIMRSISGFTALDQIVTGRSDDLSKVHPIEPATLPNFAYGMHGQLAKTTPESILNSEYIQLMDAGMSNNLPIYPLLRPGRDVEVIIAFDNSADIKNDNWLAVTDGYARQRKIRGWPAGIGWPKHVAPEEAGEQIEKAGDRSPAEARSAIDKAQEQDMARGSNMKSSNIAKEHGLGYCTVWVGQTSETNTESNGDVPPPKAIADFTESGVSWNTAGIAVIYLPLLANGKVPGVDPRMSDYLSTWNFVYTPEQVDSVAALAQANYSEGKQQLRACIRAVYERKKKVREDKVKAMKIEKLRRQLRKGIVNKLGEGDHFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI48</accession>
    <name>A0ABR3ZI48_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uroporphyrinogen-III synthase</fullName>
            <ecNumber evidence="2">4.2.1.75</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HEM4</name>
        <name evidence="2" type="ORF">Cpir12675_000967</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.75" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000013">
        <property type="protein sequence ID" value="KAL1900385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004852">
        <property type="term" value="F:uroporphyrinogen-III synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06578">
        <property type="entry name" value="HemD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10090">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036108">
        <property type="entry name" value="4pyrrol_syn_uPrphyn_synt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003754">
        <property type="entry name" value="4pyrrol_synth_uPrphyn_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039793">
        <property type="entry name" value="UROS/Hem4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12390">
        <property type="entry name" value="UROPORPHYRINOGEN III SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12390:SF0">
        <property type="entry name" value="UROPORPHYRINOGEN-III SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02602">
        <property type="entry name" value="HEM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69618">
        <property type="entry name" value="HemD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tetrapyrrole biosynthesis uroporphyrinogen III synthase" evidence="1">
        <location>
            <begin position="60"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="337" mass="36505" checksum="17DDC01C284CE90F" modified="2025-10-08" version="1">MEPLSQASLERRRIPVLLLKTPSAPTDAYRDLFNSSQSQAQSGHRSDSLGPAVVSSNCSFEPRFVPVLDHHFDEVGIQQLANILSDGGVGPHESCKYGGLVFTSQRAVEAFAHVLVEGRKKHGNSWPKELSEVPFYSVGPATTRSLAAAAQPGPTFQIFGEETGNGDALSKYILEHYRAWYPEREALPGLLFCVGEQRRDIIPKTLMDPELPASRRIMVDELVVYGTDQMTSFESDLENLLQEYAAQTPPAETLWAVVFSPIGCDGLLRKIGALGPTGRAVLGQGDPRVLVATIGPTTRAHLVDSFGYEPHVCAAKPSPTGVLNGIATYMAQHAPCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI59</accession>
    <name>A0ABR3ZI59_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GPI anchored serine-threonine rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001085</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000015">
        <property type="protein sequence ID" value="KAL1900084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045245570" description="GPI anchored serine-threonine rich protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="157" mass="15230" checksum="37FF3B8B8F392946" modified="2025-10-08" version="1">MKFSTAAIFIAASAASVAAVDESCNAADIVKACIDMTQPRVDACTGNDWSCLCSAHTSLVTCYNNCPNDPEGFSAQQQVDSYCAAASQFPASTAASGAATGTGSVATATTTGSSRSSSTASGSGASASETASLETTGAGAKMAISGAAIVAAFAALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIF2</accession>
    <name>A0ABR3ZIF2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_000919</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.130.10">
        <property type="entry name" value="Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain (AZUL)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032353">
        <property type="entry name" value="AZUL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042556">
        <property type="entry name" value="AZUL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044611">
        <property type="entry name" value="E3A/B/C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700:SF8">
        <property type="entry name" value="HECT-TYPE E3 UBIQUITIN TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16558">
        <property type="entry name" value="AZUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="7">
        <location>
            <begin position="968"/>
            <end position="1325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="163"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="289"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="481"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="291"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="308"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="343"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="5">
        <location>
            <position position="1293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1325" mass="148691" checksum="1E31C4D09A496A64" modified="2025-10-08" version="1">MTRESSRRSVFGATANATAAQADMTAYNDLLGLLWEHTTFPRLPHDAPQELRDYLVSLDDPRQVYKVHHASRRYGFMTLVEKFVHQLQHGCGSPSCSTSTCLTCRQHVFGSAPIRRYNPNSARTLAVYFASQDSPERLLCPFLLPPSTPSDTVNSLSFSQSPWYQNRASPTPSGSKAALAQKRIGPSKHRRVPLAPVSPQDSKGTSTDSSHGQHSSSSSIGASGPHLVISEKPVSKDHRSVSANVFGTVAFRMLEWLTPNSLAAISYKASAAEQDDIALQEAAAIPLPSSAVGSPRSQSPVCGSSTDFTKHGPKDNDVPDSFVPYFQDHDTSSSEESYCYPATSESSKSSGTNRNQASGSLARQSSNAHVKSALIPPTTTTSPKTSRRLSQDLHPQPVDDHLSQSLVSPKLALPEKQLKHARPPQSAPNRSLSEIVPHVDFFEAHNKANRKTSSLDAESPLKMKPWPPSMQDIAVTPPIFSEDVDASSSNSSRDTELKSTSDNGLAEKPTATSPDDMTLLPQSLDHLSLEIIEFVYRAMKEDGTAEKHYFRPARMSRETPEEFGSKLFRIGRPKSFSQYSAAMRSEWQSFFIQSIFHSLSCPQALIKSFSRDGSLLSSRAMWWGLAKLIDSQPTLVFHSLWMASSSLFSVPKPLQVLRSPTTQVFRKSDVSLTNKEAGEIMTICLHALVALIPEVSSRNTLYDISRLRSMGLSVASKSKATTETYLQCDDAYTDEVALRLARRLFLALVARRHYADMGAVTWLSDGEDAEWDVLQPLWNQLDQLNVDDKDASHLERVVVILLDWARTVIIRDWDGEGEFNCNSAFAGAFMLFEHMYSKRRELFISDINLRIDYFSERLDCTALPISWINFTSSSKRKHILDYPFIFSPATRVSQFRAINFSRMNRGYEDSTSAWETTRNPINSTPISNMFLSDFLHERMKKYTSKYLILHVSRENIVKDTFDQLWKRHEHELLRPLKVHLGEDDGEEGFDSGGVQQEFFRHVISKCLDPEYGAFTIDSRTHMAWFVPGSIVESWKFELIGLLMSLALFNGLTLPVTFPKALYRRLLGCPVSDLQHIEDGWPDLANGLTTLLEWDEANGLIEDVFARTYEFSVDMFGEPVSRQMDSENPEWPQLGAVALGQQTLVADNPEDAPMVTRSNRSTYVNDYIHYLTDVSIRTQFQAFQRGFNTCIHSKSLQLLTPPLLQSLVEGIQEIDISELRRYARYVGWDASHRTIRDFWSVVKRFDSSMKRKLLEFVTASDRVPVGGIKNLQFVVQKNGEETGDHPRLPTAYTCYGTLLLPSYRDKEQLKERLCMALENAQGFGFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJF2</accession>
    <name>A0ABR3ZJF2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001174</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000017">
        <property type="protein sequence ID" value="KAL1899953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021840">
        <property type="entry name" value="DUF3433"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37544">
        <property type="entry name" value="SPRAY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11915">
        <property type="entry name" value="DUF3433"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="686"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="752"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="804"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="945"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="986"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1048"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1086"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="553"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="553"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1194" mass="128628" checksum="EA89C40459E783B0" modified="2025-10-08" version="1">MFTSLISHTARTPRSSIQNFPPYKSNRSPASLAGLTAYDSSPSHSSHSEPPQPTFTRLTSYTAKKPGKRRHMRAVRRHHKPLSLRAHIVAIYIGIVTVLLVFFVVAQQVSVHDDATDGKPAYQVRSLDLAERSRRRNSLKSSEEKHQNFLALGRQMPNITSSVDISKEDTLMAALEETTSPKIAETPASSVSLETNYIDAFSAPMTSETRILSAKTSEVLPAASIMSMTVTPEESVIILTATASGSSLFHSAQNIASQISVSSEEAPALTETKTQTAIIDKLTSIYTLASTTEAPTAPSQTQDSGLELSIKVLPVPSQHLVLSDTLSPTRLPESENSATLSAAIPVTSSYKANLQNEASLPITTPSLTVPNVMVAVALTVSNTQIPKPSSIPVASVPSANALSDIQSSWTTNSYTLLAAQNAPTDLPTIVEGALSTGHRTEIQPQESIQSVGANMIVYETTLQAASPYLNSASAQVPSSDLGSTRASNPAVAFTTPSEITQQDSLTLVLTSQTLAPAASDRSQFLEQANPTQSAASLGISTLITLQMPASAEKSQSLLPVPKTTSQESSAHRTLPATKTPEPAIKEILTQPESLVTSIMVLTSPGYMTIFTSTGSPITSTFTGADNTLHTTTTTPEVLVTSSVSPTVVTRTAVFTLFPESTSSTNLHSGPIPADMPEFTITKMHNFLGHFLAPLLATGLLVCAMTLDQNAKMYQPFALLARREGACAEDSLTLKFYGLHSVLTPFRLLRKGLPLTALTTLLMWISWVLIAVSAEAVHLISEAPCKSGDTLCAVKLSFRPVPSHAVIALMAIMLLLLIGLVVVLWKWDSGVCANPWSIAGIAALLSHYITREPLIGLPRVTHQKEIDAVYKGKEYQLNLFQGRGGLLEYGIAPGESTAALRPTNNDTDGPHALVAKSTKKPNFIDMVKDAVAKDKRQPFFALSIRARLLFIMYLVLLVAWIGYYTQLEDAKDRMVIFMNSGEFGPKFLLAMFGVVVAVAWTHVYQSIAILGPFLVIKAAPHHAETSVLVTRASNAYLGLWVSIKRKQPLTMVAATLSIVADFLPLIMCNIPQRSGSPIMRTTHNTCSALALAILVFMIAMLLLSLIVKLPYMPGDPRTIAGVGVYIADSRLISEIKQFQTSMVDSRQREAEIKELGIRFVMGDMVGVSKARRYGVEVSTAVHQSKHQERGMESPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJM2</accession>
    <name>A0ABR3ZJM2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Chloride channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">GEF1</name>
        <name evidence="11" type="ORF">Cpir12675_001043</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the chloride channel (TC 2.A.49) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000014">
        <property type="protein sequence ID" value="KAL1900359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04591">
        <property type="entry name" value="CBS_pair_voltage-gated_CLC_euk_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03684">
        <property type="entry name" value="ClC_3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3080.10">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="ClC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45711:SF9">
        <property type="entry name" value="ANION_PROTON EXCHANGE TRANSPORTER GEF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45711">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7 9" id="KW-0868">Chloride</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="147"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="183"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="249"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="326"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="360"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="414"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="441"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="490"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="522"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="575"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="675"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1900359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="803" mass="89039" checksum="A83998DEF0D8E642" modified="2025-10-08" version="1">MGVDYNVEYGLRNEAGEQQIEEEIAEIKRYEDFTTIDWVQDAVREHARRQLRKQQLSGWRNNNGKVGWKYRLYESYEAGQAWMVVTLIGMAIGMIAAIINIASEWLSDIKIGHCKTAFYLNEEFCCWGEDNGCDAWENWSGFALINYLIYTFMAVSFALASSSLVQAYAPYAAGSGISEIKCIIAGFVMKGFLGFWTLFIKSVALPITIASGLSVGKEGPSVHYAVCTSNVISRMFGKYKQNASKTREVLCAGAAAGVAVAFGSPIGGVLFSLEEMSTYFPLRTLWRSYFCALVAVATLSAMNPFRTGQLVLFQVQYDRSWHFFEILFYILLGILGGLYGECMIYLNLKYQAFRKKRLSSYPILEAVVLAAITAVLCYPNAFLRIEMAKSMEILFLECEGAEDYHGLCEKEKRFWNITSLLLATALRFGLVAISYGCKVPAGIFVPSMAIGASFGRAVGIIVQALHESSPESMFFSSCKPEEPCITPGTYALLGAAAALSGIMHLTVSVVVIMFELTGAVDYILPTMIVVGMSKLVTTLLGGKGGIADRVIPFSGFPFLDSKEEHNFGVPVSRVMRTAVVTIPMTGLELKDVENLLSSDKYQGFPVVESQKNRILYGYIDHIELRYAVDRVRRNRPVASSTPCNFIPPHAAARFLREDNPDTSPADALIDFGRYVDSAPITANPNLPLETAIDLFCKIGPRVILTEFQGKLVGLVTVKDCLKFQHKVEGTEIGVRDAFEDAHEKLWLLIQRVSGWVADRVLSVSGGRIHLRAMNDHMAFSQRDTMMPSTLQEEGEDEIELSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJQ4</accession>
    <name>A0ABR3ZJQ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000888</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="220" mass="25116" checksum="D3D2ECEBC92BFE92" modified="2025-10-08" version="1">MFFAITFTFWRLCQIITLICNVGMMAWFVDIFNSQNMLTPNFILVMFIVSVIALAWTIFTLFSYRRSSANGLMIAWTDILFMGAFIAAVYYQRHIGPIKCSSVSSSSGWRSHFAALYQVRGVHSLNPDSAKPCAMIKTSFAFGIMNVIFFFITAVAAWIHGDSVHDSHFRGNVTHVHRSSVSHSRPHSHSQRSHSRDSRRRSSSRHGDHRRSHSQSRVHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKD5</accession>
    <name>A0ABR3ZKD5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribosomal RNA-processing protein 43</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Cpir12675_000821</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050590">
        <property type="entry name" value="Exosome_comp_Rrp42_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097:SF9">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0271">Exosome</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="11">
        <location>
            <begin position="45"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="12">
        <location>
            <begin position="245"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1900687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="333" mass="36132" checksum="1E02905DE09C0148" modified="2025-10-08" version="1">MASEVGLPRATFAKLAPHPYLLANLDSQTPGGPLRSNGRAPDTGRSPYINQSSLTHAHGSALVRLGNTTVICGVRGETIPVSKIPGFRESNTETELLDYDLLVPNIELATGCSPQFLPGVPPTTLAQTLSTRAFSLLHSSKLVKPEDLRIRYSLPNVAAESDDNNGDKTVDEEQEQNGEAVTIAYWVLYIDLYFISFDGNPFDASWAAIIAALKDTKLPKAHWDADREMVLCSRSESLPLTITSLPVACTATVFNDKDLGTAGKGKYWLLLDPDSLEEKLCSESITMVVDKTSCKTKILGITKAGGTTISPELLSAYVEVSEKRWDEFKAVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKE4</accession>
    <name>A0ABR3ZKE4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA polymerase II holoenzyme cyclin-like subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CTK2</name>
        <name evidence="6" type="ORF">Cpir12675_001124</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family. Cyclin C subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20546">
        <property type="entry name" value="CYCLIN_SpCG1C_ScCTK2-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0195">Cyclin</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cyclin-like" evidence="5">
        <location>
            <begin position="140"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="453"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="25"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="61"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="457"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="487"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1900019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="529" mass="57962" checksum="D8535412D0250C7D" modified="2025-10-08" version="1">MPPHGPRTSTKPVPTGPNAVNYNGTGSGGRNNRSFGGGNHAPSSRPSLSNPRSQNKSHGPNSNSNGSRSQSQLQHQNSHMHTPEPDVRMVIGDVESFKGPIPDRNVVPTQYLLQQHVQNQARAVADRAHNEETLKIQGIQVIDKVRLALQLPVRTFDTAACYFHRSRLTSPEHNYHDVALAALFVACKVEDTMKKSRDILCAAHNLKSPDHPITPDDKSLERPSMNIISLERTILETVGFNFRVRHPQKHLVKVCHSLGLGDPSQEFYVTAYHMLMDMYKTLVPIKQGTYVMVLATLELTTLVTGQYITNIKEADLSRFQIRRADVVETMLDMLDLYTQHHKMTLLGAEFGLDQFLAIKIQINEEVDANPELDRYASRCSVCDKDTNLATAAIFAATTPPLSGPRNSAGNTGEGTIRFLFSAENSKLEEAEVDKYTRDEYDEYEEEVEEPIAEFNDGGSGSGSGGGGGGGGGGGGSRAPGGGGGGGRRNRDRQRHGQGHGHGPPSGPPGQDPYWHPYPKDRGRRGRKMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKG7</accession>
    <name>A0ABR3ZKG7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Splicing factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">LUC7</name>
        <name evidence="4" type="ORF">Cpir12675_000645</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Luc7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000008">
        <property type="protein sequence ID" value="KAL1901156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004882">
        <property type="entry name" value="Luc7-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12375">
        <property type="entry name" value="RNA-BINDING PROTEIN LUC7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03194">
        <property type="entry name" value="LUC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="230"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="85"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="230"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="250"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="267" mass="30263" checksum="DA909DD5CCF646DA" modified="2025-10-08" version="1">MAAEQRKLLEQLMGASASSRSAQLSLRDPKVCGSYIVGNCPHDLFTNTKQDLGPCTRVHSENLKTEYEGLSDREKQSYGFEHDYMRDLQKYIESCNMRIEQAQRRLEKTPDEIRQTNNLLKSIVDMSTNVSNGLLEVEILGEMGEVHRAIDEFYRVRQYAQSKADREKDLKDLSDTSGPSGHQKLQVCDVCGAYLSRLDNDRRLADHFYGKMHLGYAQMRKAYETFPKEMRSRARGGGDRGGDDDHGPRGSRGGGGGYRGGRNRGRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKK5</accession>
    <name>A0ABR3ZKK5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosomal protein s17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000859</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053216">
        <property type="entry name" value="Appressorial_penetr-assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34587:SF2">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34587">
        <property type="entry name" value="VWFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045241682" description="Ribosomal protein s17" evidence="2">
        <location>
            <begin position="20"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="451" mass="42516" checksum="4310BE401893B7BC" modified="2025-10-08" version="1">MQPKSFLVAILGITTAIEASVVHFPSLNVPGLTSRQFPGAGGRGGGRGGAGRGGAGGGGGAAGGGGRGAGGAGAGGAGGAGAGGAGAGGAGGGTNAGTNTGNNGNNGNNGANAAADVTCLAAGAVQAGSQSPGAQDDPAQADSATDPANFINFCNGQTLTDGKQVQEGSCNGVVMGKIPSTNNMISSILINPKHDDTIAANTNFNVDVKVSGLQAGLFTDPDTTYYSAPQDLNGQGQIKGHTHITIQDMNKDLNPANPLDPTVFTFFKGINDAGQNGVLTAAVTEGLLPGVYRVCTMTSASNHQPVLMPIAQRGAQDDCNKFTVVAGGGNGGNGGNGGNGGNGGNGAAGGGAGGAAGGGAGGAAGGGAGGAAGGGAGGAAGGAGGAAGGNNRGAGGGGNRGGGRARNQRDISGRKTAVKARAFGSPPSSSQVEPSAVVRKRGWWFQGPIFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKP0</accession>
    <name>A0ABR3ZKP0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sterigmatocystin biosynthesis P450 monooxygenase STCB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_000531</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11059">
        <property type="entry name" value="CYP_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF164">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1901298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="485" mass="54886" checksum="1B33A45EC9AE0C23" modified="2025-10-08" version="1">MAIFSPAILFGLGVVFLVARLLRRAFSPLKSIPGPFYTRLSRMPLRYHEMHANRTLWIHGLHQKYGPVVRIAPNEVAFTSPAAMKEIYNNGGSGYDKTEFYDLFKAYGRRTMFTSLVKNEHSKRRRIIADRYANSNVMRSASMSGINDRAQDFMSKCWDSASGGSIDIFRNLHAYACDCVTQHLFHPFGTRALKDKHDEEMMHQVAVDDSLRNRLIEHYSPTIHSVMSKFLGYFGVRPRDTPLADAFVLDASGQTSTAQFTLMTRMREKIGDLEQLDLAAEALDHMAAGIDTTGDVLCFLMWELSQPHSIHVQKLLQKELRDKPKASFEELPYLDAVINEGLRCFPAIPMSLPRYVPSGGRTIDGYSLPERTIVSCQAYSVHRLNPRIFPDGDCFAPERWLAAEGDADRKRLQFAFSVGGRGCIGKHLAMAEMKTLIRNVYSTFNTLPDPSMKPESMAMSDQLISSRPLGQRCLLRFEPIEKEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKZ3</accession>
    <name>A0ABR3ZKZ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Vacuolar amino acid transporter YPQ3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_000856</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051415">
        <property type="entry name" value="LAAT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201:SF44">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1900720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="319" mass="34231" checksum="0ECA819396A76763" modified="2025-10-08" version="1">MASLVARAVAVAAGQDAGTAMSGIFGSISLTAWICLLTPQLIANYKAQSADGLSMAFLIIWLCGDITNLSGSLLTGLAPTAMALATYFCFADVILISQCVYYNRLNAQKKAALAAIAAQISEEAPLLRHRSSSIGLPGSHVQHSTHEESAIDPIRKVVAGEDETLDSKPWLHNFLGLAAVYIVGFLGWYMSSKLGAWSETPSDSTGSQTIQGFPAVAGQILGYISALCYLCARIPQILKNYHEKSCEGLALLFFLLSLTGNLTYAISLLAFSQDRDYLIKALPWFLGSAGTIVEDSIIFIQFRMYGDAPRSPLVETTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLI0</accession>
    <name>A0ABR3ZLI0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphatidylglycerophosphatase GEP4 mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_000447</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027706">
        <property type="entry name" value="PGP_Pase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010021">
        <property type="entry name" value="PGPP1/Gep4"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01668">
        <property type="entry name" value="YqeG_hyp_ppase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09419">
        <property type="entry name" value="PGP_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1901578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="214" mass="23416" checksum="9F479958D8009515" modified="2025-10-08" version="1">MNLNLSATLNSWKLITRPSLCLPHYTMPTFADLPIPLDAPLKEQGKKADIRAVVLDKDDCFAYPETNEVYPLYQSHFERLKAAYPGRKLVIVSNTAGAASYDKQGRLAASVESATGVTVLSHSTKKPGCGNEIMAYFAAYPETGVTSPAHIAVVGDRLSTDMMLSNMLGSWGFWIRGGVVDSTKKSMFSRAERPLHDFLHGCGVSAPEPKYPFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLN6</accession>
    <name>A0ABR3ZLN6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein phosphatase regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SHP1</name>
        <name evidence="4" type="ORF">Cpir12675_000318</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14273">
        <property type="entry name" value="UBA_TAP-C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.210">
        <property type="entry name" value="SEP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036241">
        <property type="entry name" value="NSFL1C_SEP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012989">
        <property type="entry name" value="SEP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23333:SF20">
        <property type="entry name" value="NSFL1 COFACTOR P47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23333">
        <property type="entry name" value="UBX DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08059">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14555">
        <property type="entry name" value="UBA_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00553">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102848">
        <property type="entry name" value="NSFL1 (p97 ATPase) cofactor p47, SEP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51399">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEP" evidence="3">
        <location>
            <begin position="235"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="UBX" evidence="2">
        <location>
            <begin position="358"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="439" mass="46272" checksum="718309EAB651A041" modified="2025-10-08" version="1">MADIDEDQQIKLARVMESTGAPADVALQMLEASNWDPETAAGQYFADVASDSETPAGSSAAAAAASSSPPAPSSSYTGPRTLGGIPVPASQSRATTNSSKPPRRTGVATLSSLARDDNDDDDDSEGEDERRKRRNLFAGGEKSGLAVQDPDRGGGDHRDETNRLLDGIRRQAMAQGRRMNEEAARAPPPPRFIGNSYTLGGDGVESRMHVDPNTQAASTAASAAATAASAGHQEIVKREIHLWLDGFSIGAGPLYSFADPNNQAILRMINNGQAPLEVVNISAGQPVDVAIISHNENWRQLPRPHVAFEGEGQRLGAPVPAASSTAATEHTSTIDFTPPSSTPAIAVASSQLPTPHDESQPSVAVRVQLPNGSRLPARFNLSQTVGDIYRFASQADPTLTTRAFVISTTFPNKDHTDKAAVLGDMVEFKKGGVAIVKWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMG3</accession>
    <name>A0ABR3ZMG3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">DNA repair protein rad16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">RAD16</name>
        <name evidence="15" type="ORF">Cpir12675_000465</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF12">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="364"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="704"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="785"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="145"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="269"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="280"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="298"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1901595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="953" mass="107079" checksum="CDB696FC12DC4FB0" modified="2025-10-08" version="1">MRRATRSQTQALSTQVAGDQPQASGAADSQTLSQFRRYNTRSASQSATPASALPRQTPPPMAQTGVELKRPTFAISPTLSPLPRSFASDCGIVASTVPLRTPGDIQFLESGELAPVNSNNTNIQVCIPSCSPRQIAICRAEAKNMNSSDDEDPFDVDNWGSEETTRLEPGVVVLGDEPAASRPHKRPNPSAQQSSEDPRKRSRFGPNIDFTTAAEVLVEESGFASLAPSRRVSILCNADVDSSFSLPASTMSAFTLNTHVPLTPEANAEAELESNPPLEESLDDSESENSYASDDDSPNTSNRYFSQSASNHESAMLKKHPFLKTMWKDLEAMPPIEKIEAPQPPLISRQLKPFQREGLYWMTEMEKRQWKGGLLGDEMGLGKTIQAVSLIMSDFPTNKPSLVLIPPVALMQWMNEINSYTNGRLKTFVYHNSRAASRKVTVEELLQYHVILISYNSLESLHRRQTKGLARGKRGEPKVLIQTDSPIHQIEFHRVILDEAHEIKAAKACFALKATYRWCLSGTPLQNRIGEFFSLLRFINIRPFASYICRACTCESLEWSAEGGMCKHCTCPSIGHYSIFNREILNPIQKQGNYGGGREAFKKLRILTDRIMLRRQKKDHMDVMELPVKELRISREFFGDVEKDFANSIMNNSQRQFDTYVARRVLLNNYANIFGLIMQMRQVADHPDLILRKDLFGAEGVVECSICESPAEDAIRSRCKHDFCRVCAREFVAGSGQPDCPRCHIPLGIDLKQPELEQDVSNMKNTSIINRIRMDNWASSTKIELLLHELYMLRSDKETLKVIIFSQFTSMLQLIEWRLRHAGFSTVMLDGTMTPAQRAATIDYFVTNVDVECFLVSLRAGGVALNLTEASRVFLIEPWWNPAVEWQSADRCHRIGQSRPCTITNLVIEDSVESRMVMLQEKKAHMIRSTINNDSKAMESLSTQDLMFLFRGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN60</accession>
    <name>A0ABR3ZN60_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_000193</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SOS response-associated peptidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1680.10">
        <property type="entry name" value="SOS response associated peptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003738">
        <property type="entry name" value="SRAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036590">
        <property type="entry name" value="SRAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13604:SF0">
        <property type="entry name" value="ABASIC SITE PROCESSING PROTEIN HMCES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13604">
        <property type="entry name" value="DC12-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02586">
        <property type="entry name" value="SRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143081">
        <property type="entry name" value="BB1717-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0190">Covalent protein-DNA linkage</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="198"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="207"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="246"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="292" mass="32494" checksum="B7EE42A0C557FB97" modified="2025-10-08" version="1">MRTINCRSDSLAKSSGMWTSIKTHKRCIVIAQGFFEWLNTGTDKVPHHVKRKDGKLLCMAGLWDCTRYEAAGSPLPHSRKELYTYTVVTTNSNPQLRFLHDRMPVILDPGSDALRMWLDLSKTVWEDDLQNILCPFNGKLEVYPVTREVGKVGKDSPTFVVPVNSWENKINIANFFQASSMKEGSPATTSKLYTEESSLKAAKAEPSQDSGSLMDSTKTANTVSHKRFAPNEPSRSPLPPSKKYKTSIQHSSSNRQTVSATKSTKHREKQIGLSKAGANKGHAKITSFFGKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNR4</accession>
    <name>A0ABR3ZNR4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Plasma membrane low glucose sensor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SNF3</name>
        <name evidence="10" type="ORF">Cpir12675_000166</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17356">
        <property type="entry name" value="MFS_HXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF17">
        <property type="entry name" value="HEXOSE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="277"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="383"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="416"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="20"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1902060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="532" mass="58498" checksum="303C54AE1B35F22F" modified="2025-10-08" version="1">MGFLVDHPPTAGATWPSIAVGMFAAFGGVLYGYDTGTISGILAMKYWLKTFSTGYTNQDGSPGITSGQESLIVSILSVGTFIGSLISPLLSDRIGRRLALVIVTWVFNLGVAMQTAATSQDLFIAGRFFAGLGVGLISAIIPLYQSETAPKWIRGLIVGSYQLAITIGLLLANVVNNATHKNDDTSSYRVPIGVQFAWSLILFAGMLFLPETPRFLIKQGRHEDASKSLCRLRRLDPDHEEIQSELAEIRANHEYEMSLISESSMLHAFKPPMLKRLITGVGVQCFQQLSGINFIFYYGTKFFENSGIKNPFVISMITTSINVVSTLPGIWATDKYGRRNLLLIGAAGMAASQLIVALTGTLSTDQTDTGIIIVKNLAAQRTAIAFICIYIFFFASTWGPLAWVVCSEIYPLRIRAVSVATTTASNWAVNWALSYSTPYLVNWGPGNANLQSKIFFIWFGCCFLAAAFVYFFVYETKNLTLEEVDELYSQVPHAWKSAGWKPTLRFADTKIPDHDKPQQMGEHVETATKVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNU8</accession>
    <name>A0ABR3ZNU8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_000248</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14653">
        <property type="entry name" value="ZIP_Gal4p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF10">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="78"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="136"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="703"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="767"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="163"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="198"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="709"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="722"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="740"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="767"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="806"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="841"/>
            <end position="883"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="951" mass="104049" checksum="DF2024E07EF5D887" modified="2025-10-08" version="1">MSEPGLSTVANTAVAATAVTTTATTGPMPTTEADLVPTTTITTPTAQDLTTEAASTTTAPSAAPRPDNLFVPKPKRLACMICRRRKLKCDGVKPSCSTCARLGHTCAYDEVRRKSGPKRGYVKALEERLKQVETLLKTQEPPAVAAATRESPSVPRNVPEPVSTAQKSTATPPSAFRPNSAFVSSENDSDWRFKHSSPHASSATRQQTPRAQSQPGSTPDDTGRSAYNHTIPPPMAENHRQDLVDLGLEEPLPFQDAIDELHKIFFEKVHASVPMIHRHRYLAAMTLPPAQQPPVALRYSIWTLASCVSEKYYATKDIFYQRARKYVELDYLKGFGEHIISIAYAQAHVLIASYEFKMMHFPRAWMSTGSAVRLCQMIGLNRLDSSGLDVKQCLPPPRDWTEHEERRRTFWLAFCEDRYASIGTGWPMTIDERDISTNLPSSEEAFDMSKPEQTGTLKDALTPAGASKLSAFASVVLSSAMFGRNLIHLHRPDPEDRDHDLNGEFWKRHHQLDGIILNTLMSLPANLKLPEGLMMPNVVFVHMSMHTSTICLHQAAIFKADSYHLPANVSMESKIRCITAANEITYIMRMVAHLDLSSMNSFVAFCLYVAARVFVQYLKSQPEDTQVADSLRFLLGSMTALTRLNPLTESFLVQLDVDLDTLMARNPRLHNAFPRASELPTSHPVSALAGGTYSKMPISAQLRPGFETHGSENRFMHPLDDNSVNSQTSAANKLSPPPDSTSTRHTHPPTSNSMLASQWLKVSGQSNANIPMAPTMTTSPHSGTSVIGSVGGGDSSAEPIDVAMSNHGTPSASNRPTPNSICSDQHQSDQHKQHSLHASRSIPSQSTPLNNPATSGSGHTSFNTTSVSQDHSVPPNGSSYTSGGNLFGMSPSVAHGCFNAETTNDPNFVNSWPEVGQAQSMTPMAEGVLRTFMNLVPMDAMDMSTWDQHIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPF0</accession>
    <name>A0ABR3ZPF0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">YTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_000020</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21134">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.590.10">
        <property type="entry name" value="ph1033 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007275">
        <property type="entry name" value="YTH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045168">
        <property type="entry name" value="YTH_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12357:SF3">
        <property type="entry name" value="YTH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12357">
        <property type="entry name" value="YTH YT521-B HOMOLOGY DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04146">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50882">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YTH" evidence="3">
        <location>
            <begin position="254"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="249"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="63"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="268"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="425" mass="48130" checksum="6585C96CB198685E" modified="2025-10-08" version="1">MSTPIPPAVISDAVPAIPPVTLENTTTSPELAEALAKDPELHLWLTNTGYFDLAKRTKVLKTYHKLAQADQSARRRLAELKEETAKHQAAIEQERAQILQELNSHDPSSISVVPESRVAHQTAIQDYLAEYATDTGPDAANLQTWTTSEKTLDPASKHLCKSQVVKPEYFGSFSPANLRRNTDYHTRKSSASGIQLGSHKDNTIELLRYKNSKPFLSAISRPIRTAYSLDEWMQDSARRARSPVNLYTPRVSHRRTPSPRANNSDRLNSYRERDMHSNGRSLRDMNIDDEENTRFFIIKSFSYENVDQCMANAVMKKPPSLGVPPPTWAKRIRWHASHPFVVQWLNTTEIRFSHIPHLKNPLNESKPIFHAKDGQEIPFDIGRKLVAIMNDESKAINSPIQGVSIKTERGGWAVEQKITRDSAKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPQ8</accession>
    <name>A0ABR3ZPQ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA-directed RNA polymerase subunit beta</fullName>
            <ecNumber evidence="9">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">rpc2</name>
        <name evidence="18" type="ORF">Cpir12675_000057</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1100.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007646">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007647">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04566">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04567">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9 18" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9 18" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 9 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase beta subunit protrusion" evidence="14">
        <location>
            <begin position="43"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="13">
        <location>
            <begin position="193"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="15">
        <location>
            <begin position="455"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="16">
        <location>
            <begin position="557"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="17">
        <location>
            <begin position="639"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="11">
        <location>
            <begin position="686"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="12">
        <location>
            <begin position="1064"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="804"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="857"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1044"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="817"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1044"/>
            <end position="1056"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1902157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1158" mass="130252" checksum="3F182A593465EA40" modified="2025-10-08" version="1">MVVLDDGFEALLEPFYNGKKLTDPISTREDKFQLLPAFLKVKGLVKQHIDSYNFFVEHEIKEIVAANRTIKSDADSTFWLEFLDIRVQRPNRQDESDFPPNSEVTPMECRLRDMTYSAPIFVDIAFIREKQRVVRKNIRLGRMPVMLRSSKCWLSGANNSQMEAMNECPLDPGGYFIVGGTEKVILIQEQLSKNRVIVEADEKNNIISASVTSSTHERKSKTYVQFKKDRIVLSHNILVEAVPIVIVLKAMGGLSDLEIMALVCGSDGRYQDSFAVNFEEATKAGVFTQQQALEYVGARVKMGGRRMPGGPQMRRNHVEEGLDALANLIIAHVPIEGLDFYPKAIYIALMTRRVLFAMHNSTLVDDRDFVGNKRLELAGQLLSLLFEDLFKRFMSEVKMSIDKYLKKNNRAIALDPVNIISNHANSIGQGLNRAIQTGNWNVKRFNMNRAGVTHVLSRLSYIAALGMMTRISSQFEKTRKVSGPRALQPSQWGMLCTSDTPEGEACGLVKNLALMTHITTNVDEEPVKRWVFTIDPTAESIRNFTGQEMHQPGNYIIHINGTPLALTRYPKQFTAKFRALRRKGWISPFVSVHMNSHFSAVHIATDEGRICRPYIIVKSGKSNLKAEHLRLLQLGKATFDDFLKHGVVEYLDVNEENDTLVALNEDHLTNSSTHMEIEPFTLLGAVAGLIPFPHHNQSPRNTYQCAMGKQAIGAIAYNQFNRIDTLLYTLVYPQRPMVISKTIELVRYDRLPAGQNATVVVMSYSGYDIEDALVLNKASIDRGFGRCQVFKKYTTELQKYANGRQEQLGRPVNEGEGESRRRVPRDEALDDDGLATVGYRVRAGEVMIKKETPIDQASTGIGADRGPSEYRDSSTTYRTPDPSYIDKVMLSSTEKDTVVVKVQTRQTRRPELGDKFSSRHGQKGVVGIIVDQEDLPFSDAGLVPDIIMNPHGFPSRMTVGKLIECLTGKASVLDGRKDYGFGDAFRSHPVEDMGRVLIEHGFSWEGKDYFTSGITGEPFEAYLYNGPIYYQRLKHMVQDKMHSRSTGPRASLTRQPTEGRSREGGLRLGEMERDCLIAYGASQLLLERLMLSSDAVQIDICQRCGLFGYKGYCTTCDSTGEVTKMTMPYAAKLLVQELISMNVGVRLQLDDEFPHPNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQG9</accession>
    <name>A0ABR3ZQG9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">U6 snRNA-associated Sm-like protein LSm6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">LSM6</name>
        <name evidence="17" type="ORF">Cpir12675_000267</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6.U5 tri-snRNP, and free U6 snRNP). It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 15">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01726">
        <property type="entry name" value="LSm6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016487">
        <property type="entry name" value="Lsm6/sSmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021:SF1">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006609">
        <property type="entry name" value="snRNP_SmF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 15" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="11 15" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="12 15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 15" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="10 15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="9 15" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="8" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Sm" evidence="16">
        <location>
            <begin position="13"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00025365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR006609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1901759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="82" mass="8881" checksum="2550A21FFE2D5FE1" modified="2025-10-08" version="1">MENTAAARADGKDPSGFLSDIIGNMVTVKLNSGVVYKGELQSVDGYMNIALEKTEEFVNGVKRRAYGDAFVRGNNVMYISAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG09</accession>
    <name>A0ABR3YG09_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinetochore protein fta4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000358">
        <property type="protein sequence ID" value="KAL1887069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025207">
        <property type="entry name" value="Sim4_Fta4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42040">
        <property type="entry name" value="INNER KINETOCHORE SUBUNIT FTA4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42040:SF1">
        <property type="entry name" value="INNER KINETOCHORE SUBUNIT FTA4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13093">
        <property type="entry name" value="FTA4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="277" mass="30469" checksum="8FBA80679A96085D" modified="2025-10-08" version="1">MAPPTILALKQAFITTQTGLLASDLVPSPAWFEAQATVDDPLPARAVDDALFRLSHALTQHSRRVHAPQATRHVAEQLDRLYWQATERGADVNTVDGDMSNGVGRHVDISMTKPISNLPPTWPSETQSHAFPAESQRYTHLVASLTNLDAQRAAVLARVQRLRRIRASLAPLQPIPSKRARSHSEDPDTDAGSDANADGHVVAQGSREDSNEAVRNVIQENLVARNGAIEKELERMRILLARVGGRVSRLKAESDEELVIDIREAEKKKVDAFLDTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH17</accession>
    <name>A0ABR3YH17_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">E3 ubiquitin-protein ligase PEP5</fullName>
            <ecNumber evidence="9">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">VPS11_2</name>
        <name evidence="13" type="ORF">Cpir12675_006682</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex. Component of the class C core vacuole/endosome tethering (CORVET) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endomembrane system</location>
            <topology evidence="8">Peripheral membrane protein</topology>
            <orientation evidence="8">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Vacuole membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the VPS11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000349">
        <property type="protein sequence ID" value="KAL1887142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16688">
        <property type="entry name" value="RING-H2_Vps11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057308">
        <property type="entry name" value="CHCR_PEP5_VPS11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057307">
        <property type="entry name" value="PEP5_VPS11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016528">
        <property type="entry name" value="VPS11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024763">
        <property type="entry name" value="VPS11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323:SF24">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23341">
        <property type="entry name" value="PEP5_VPS11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23356">
        <property type="entry name" value="TPR_PEP5_VPS11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12451">
        <property type="entry name" value="VPS11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17122">
        <property type="entry name" value="zf-C3H2C3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007860">
        <property type="entry name" value="VPS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0926">Vacuole</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="CHCR" evidence="11">
        <location>
            <begin position="403"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="879"/>
            <end position="918"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR007860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1887142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="972" mass="108994" checksum="A76302D9E5B95B0A" modified="2025-10-08" version="1">MALSWKSFDFFDIASVKLLDEETRIFFQSNEISCLCTGSDNLFLGSFDGYVRIVNSKWKIVRSFLAHDVGTITHMRQIDGTSLLVTISEDLSNAPVLKVWALDKPVKKTNIPTCLTTLSINNNKKQFPISAFAAHEGLRQIAVGFANGSVIVIRGDLINDLGAKQRIVHESDEPITGVELSADAPDTNLFISTTSRILRISISKKGQNLPAKTVEDVGCGVGCMSRDKKTGDVIVAREDALYYYTIDGRGPPCAYESAKSMISSYRDYVALICPPTTETSQAQSEPMKRFGGASDMLNVSTFYLLEPSLRVIAHTESVVSPVKHIFELWDDLYTLAQDGKITRYHEKNLQSKLDMLYQRNLYPLAIELAQKSGLEPEQQNQIFRKFGDFLYQKADYDGAMMQYIRAIGTTEPSQVIRKFLDTQRIHNLISYLEQLHEHRKATADHTTLLLNCYAKLKDIDKLEKFIKSPGDLKFDLDTAISMCRQGGYFEQAAYLAEQHGETEMVVDILVEDSKKYKDALDFICHQHPDTAFPCLMKYARVLIENCPKETTKVFVDYYTGRYRPKIDTAPMESEIRAGSGIAATAVQNLTNFIALPYLNNSAIASPGTPGRNEVKNTVILADEDDIPAPKYMAPPPRTAFSSFIDHPDEFIQFLESCLEEPDAKESDKTDLYTTLFEMYLRKSVESKGERQEEWESKAKKLIERDSTPMESSNVLLLSDLSDFKDGTTLVKEQSGLLFDIFRSYTSAKDTRGAMKALRKYGNKEPQLYPAALTYLTSHPSVLEEAGVSELANVLNKIDKDRLMAPLQVIQTLVGQAQKSGGVATMGMIKPYLSETIERERREIGVNRRRITAFRAETEQKRAELVEISTRPTVFQATRCSDCGGGLELPVVHFLCKHSFHQRCLRGGGAEPDAECPLCAGENATIRALRRAQEDNASKHELFKTELERSEDRFGTIADWYGRGVMSHAADGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI58</accession>
    <name>A0ABR3YI58_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000304">
        <property type="protein sequence ID" value="KAL1887655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="477"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="172"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="490"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="517" mass="57221" checksum="461030B22151627B" modified="2025-10-08" version="1">MPPALTPQIYSHDPSSLSMALAPTRPVSVVPDFRNPFAGQHVPVQPQLQPQIQIHQPSFVQPRRPPSMRQLAPQAEMPYHADPLTYPRPHAFSRPVPLSHSQAQAQAQAQAETQFLDPSLDPNISPDDISPHHPLYHSSGPDDDQLLTRRHSSMRLRRASGAPSLAGGYIMPGPRRSSSSTSQPHSLPPPALHLDGVEDGRDVVELGLDHEAIDGNENVDNLEIDIDGIGVHDARPSSRVSRASSHQMPSISPRRASVQPSVWNALARRPSRAAYMDKSDEDVADEYGDLRNGDTLSNRRASVGERLAVPSSPYDSRLGGGFGVSGLGVRRPSECEPVCSPRTVPLAAYADRETRNRRRYSTADISAQVYTQSHARTYPHAHSHSRIPRHHPHAPGRRTPPYVEHSPLRQSVRYVGGSLHRRPHFHASHHSRSRAAPFWIHETGGDGQAARWTTGAHAPECRCRACREEARESTYGFEPYDSFDGSDGSETWDGDDNDGDDEYLLDEGGRVREYVRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI96</accession>
    <name>A0ABR3YI96_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">WD40 repeat-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AIP1</name>
        <name evidence="4" type="ORF">Cpir12675_006456</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000303">
        <property type="protein sequence ID" value="KAL1887685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19856:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19856">
        <property type="entry name" value="WD-REPEATCONTAINING PROTEIN WDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="54"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="185"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="229"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="531"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="574"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="609" mass="63714" checksum="1564443BF2015D4F" modified="2025-10-08" version="1">MSITLDRILAAAPTTARGQPTPISVDKKGERIAYASGKSIFVRSIDNPADCKQYTGHTAQTTVARFAPSGFYVASGDVSGSVRVWDAIGAENTKGEYSIISGRINDIAWDGDSQRIIAVGDGRERFGHCFTADSGNSVGELVGHSKTVNAVAIRQQRPLRAATVSDDGSMCFMHGVPFKFNSKADNLHRGFVFATAFSPDGSKLVTVGADKRIQLYDGKTGEPTTVIGEGAHTGSIFAVSWSEDGTKLVTSSADQTVRLWDADTGAQIQSWRMGPEGSVSVSDQQVGVVFPHGRTDGLIIALSLSGDLTYLKAGTAEPVKVVQGHNKGVTAVTAGSASDKAAWTGSFEGRVCKWDLTTGAGRMVDGSGHSNRVAAFSSRLGQTHTIAWDDTLRCMDEATGTFIGEAIKLNGQPQGLSADSANGAVYVALASEALAIYQDGKLIGEAPLGYIPTAVTAAGNTLAVSGDGSKVNVYEVEGAKLTKVIELTHSTAAVSVLAFSYDGTLLATGNSAGKVIVYKAGGDWDVATDRWSAHTARVTSIAWNAESSHAVSGSLDSSVFLWSLEKPGNRISAANAHKDGVHGVAWVEGDSEIISSGADAALKLWNFEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIW0</accession>
    <name>A0ABR3YIW0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000277">
        <property type="protein sequence ID" value="KAL1888123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="340"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="488"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1004"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="117"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="137"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="165"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="199"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="217"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="287"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="306"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="345"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="492"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1075" mass="118336" checksum="9C170F341E2EE490" modified="2025-10-08" version="1">MSMSFEPSTANTSATRIPLSRLGSTDGAQSFPPPPGAETRRPSRERRFGLPSLSRRRDQDQAQTRNQLSVGGPMGSIGNNFRGLSVHVPSNHTLGLDQPSDPPSARRAASTSAIGTPGSTDWTARQGQGLQWGAGVPIPPPPPGPPPPQARSQSVQSFDRDRPIVSPPTRRPPPSGVSALGPVPPTPANWIDDAVITASPPPPPPPLLPQQQQTLLSASCSQQQPMPAGSSPTGSDVTVDMQTQSGSQSSSVNIDKTIAQRRSESRIRSDCSSLDHAGTPSEISIPPATTLSRSGATRITPRSAKFNETPTSRTSEPPKSAGSLRVDTSVGVAQPLPQAAEKAIAQTPPARSSSRAPSTERRADTLGDMSQFALLEIKQKAVTQTADQFSNETIERYQTFAVKEAAAASDTERVRLFAEFIVAESRIRRERYSNAISIMGSEIFDLTRDLFRPVASRRSSSVSRSDWTPQSSASLLQTASTTNTNYRDSMELSSSAPTSAAMTSSLPPSPSSMNNGSQRQNHGFMPSLSPILSLSIVDDCDSRGRPVSRWWEAGSEGRVEESLLRSKRESKYMGVPKEAREALQWEDEPQASDWHQPGSSRAHGDLLHEKRDDNLTPHDNQFPALTPIKSTQQSTPIPVPVDVSRLVTMPPPYPRHHPAVNNNHPDLADIRSEIRVLSNMSDISSKGEEFEAKSSKLRATLSHEQEATRQKLLRNLRTMIDSGELSYADAGAIEKDHKEQERLKLKELDKKYFDGFQREVVVPLNEMLTTRIAKATELLNSLATGLLNQSDNAADLPQEEGDDQPELLEKLALLKWIFETRESLYKAIFDLLSARNGKYRNLILTPYRLSGNEEKVRSTEAYFRDDEIKRNSAFAVEIRDRTLEFLNVIEHSVMRGCQAQLNAFWDIAPPLGRVLEKVPSSLERFCIQIPASEYEENPAYYDHPLQYLFSLLLHGEKSTFQFIESQTNMLCLLHQVKEASAHAQAKVIETEILGEGIGESISAEDRARRAQEMLKREIEALSLDLKEKVRTVEDQWKSGFGEVVESVKERIGEYLLQTGGWDEQLEEGGPTVGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJG9</accession>
    <name>A0ABR3YJG9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Multidrug resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">CDR1</name>
        <name evidence="12" type="ORF">Cpir12675_006199</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000264">
        <property type="protein sequence ID" value="KAL1888362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03233">
        <property type="entry name" value="ABCG_PDR_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029481">
        <property type="entry name" value="ABC_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034001">
        <property type="entry name" value="ABCG_PDR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010929">
        <property type="entry name" value="PDR_CDR_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14510">
        <property type="entry name" value="ABC_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06422">
        <property type="entry name" value="PDR_CDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="514"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="546"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="622"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="654"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="766"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1183"/>
            <end position="1202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1214"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1257"/>
            <end position="1284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1304"/>
            <end position="1326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1338"/>
            <end position="1363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1454"/>
            <end position="1475"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="147"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="846"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1888362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1494" mass="166978" checksum="940E3CD1422DEFCD" modified="2025-10-08" version="1">MRIMSDPTASGAPLSGDQAPGLSPPNQTARPASATSEKHMSLPGSDTAGDYDSEMERRHSIVQDLARAYTSQSHADVSGTPFTAGENSPLNPASKNFSARAWAKSVVKAVQDAGSQFRTSGVAFQDLNVFGYGEATDYQKSVGNIWLALPNMVRTLSGNKGRRIEILRDFNGTLSTGEMLIVLGPPGAGCTTFLKTIAGEHNGINIDENSKFNYQGIDSKEMHSAHRGEVIYTAEIDAHFPNLTVGETLSFAAHARQAREIPNGISRDAFAQHMRDVTMAMFGISHTVNTCVGNEYIRGVSGGERKRVTIAEACLSQAPLQCWDNSTRGLDSANAVEFCKTLRLQAELFGSAAAVSIYQAPQDAYDLFDKATVLYEGRQIYFGPATEAKGYFESLGFECPDRQTVPDFLTSMTSPRERIVRKGWEGRAPRTPDEFATAWKNSDQYQRLKGELVEYSQAHPINGHDADAFRISKRAQQAKNQRNKSPYTLSYVQQVNLTLWRAWRRLIGDPSVTIGQLIANSVMGLIIASVFYDLQPVTSSFFQRGALIFFACLMNAFSSALEIFTLYAQRPIVEKHARYALYHPSAEAVASMLMDMPYKILNTLVFNTVLYFMTNLRREAGAFFFFIFMSFMTVMVMSMIFRTIASASRTLSQAMVPAAILILALIIFTGFVIPIDYMLGWCRWINYIDPLAYAFESFMVNEFAGRQFLCDSFVPNDSSLSEYSNIASTNRICTTVGSVTGESFVDGDRYMGTSFQYENGHKWRNVGILVAFILFFFFTYIVCAEVVSERRSKGEVLVFRRGHKPAAFDEKAKDDLENLAVGPMATHDRASTKQGEPKSEMDSSVFHWENVCYDVQIKDETRRILDHVNGWVKPGTMTALMGVSGAGKTTLLDCLADRINVGVITGDMLVNGHSRGSSFQRKTGYVQQQDLHLETSTVREALNFSAILRQPAHVSRQEKLAYVDQVIAMLDMEEYADAIVGVTGSGLNVEQRKRLSIGVELAAKPPVLLFVDEPTSGLDSQTSWAILDLLEKLTKAGQAILCTIHQPSAMLFQRFDRLLFLRRGGQTIYFGEIGKESKTLTSYFERNGADPCPREANPAEWILEVIGAAPGSQTDIDWHETWKASQEAEAVRSELQNLHSKASGQTVSNDETEYDEFSAPFSVQFEQVLTRVMAQYWRTPSYIYSKFTLCLSISLFIGFVFYDAPNTIQGLQNQMFSIFQLFTIFGQLMQQTLPYFVIQRDLYEVRERPSKVYSWWVFMLSQIFVELPWNSLMAVVMFFCWYYPIGLYRNAEPMDQVTERGGLMFLYLLMFLLFTSTFCAMVIAGFQTAQAGANMGNLLFMMSLIFCGILASPDDFPGFWIFMYRVSPFTYLSSGMLSVGLANTNVICADNEYLSFEPLADQTCGEYMAAWINKEGGYLLNSNATTDCQYCSISDTNIYLDSVSASYGDRWRNIGLLTVYIVFNAVAALAIYWLVRVPKKQSPLAMLFGKKKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK52</accession>
    <name>A0ABR3YK52_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_006191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000263">
        <property type="protein sequence ID" value="KAL1888410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1888410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="250" mass="27983" checksum="32B2E9667413F7CA" modified="2025-10-08" version="1">MADPSPPMANALRQDAGPQVLEPVVLPPASPAQLLDYIVSNHAYPLTLIVGSTREEFLQALVDDVVASKSQQPVDTQARHTHPLLAASLFQIAVTKHIRLLFTPTVSHLRAYLSVFSPLDSAVPPPPGYETSAKSDNRWLVVYGMLNIHRNTSEWNAQGMMNSLSMFIDAASHTEFKPVIIEPLPIKNEENTETSMQSEYGVENQYDWQRIRAEQVPLLGYKQSSDVRLSNRTVELGKIVERWFRHLSEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKQ0</accession>
    <name>A0ABR3YKQ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peroxisomal membrane protein PMP27</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PEX11</name>
        <name evidence="5" type="ORF">Cpir12675_005999</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000240">
        <property type="protein sequence ID" value="KAL1888910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008733">
        <property type="entry name" value="PEX11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652:SF50">
        <property type="entry name" value="PEROXIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05648">
        <property type="entry name" value="PEX11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="1" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1888910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="237" mass="26970" checksum="EDAB027C5478A388" modified="2025-10-08" version="1">MTLTDAVVVPTTSVAQYLFFVLNTLGRDKIIRCLQYFGRFYTWYLLRTNGTKAQIAPWESVKKQLGLVRKIMRVGKSADHFRSLMGLIQNKTQEPVLRYMNMMHALCFTIYLSFDSATLLDATGIRKMEKAKLYQREANRFWAMGLIASMLAQSYRLFLLNERLSTIDKKEADGVVEFRKAIQERSQARTQIVCDLCDVTAPTAALGWTKFDEGLIGLTGIFSSIVSVSSKLTKFSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL88</accession>
    <name>A0ABR3YL88_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000230">
        <property type="protein sequence ID" value="KAL1889116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="491"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="641"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="768"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="491"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="666"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="697"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="768"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="810"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="842"/>
            <end position="852"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="948" mass="104459" checksum="ADE6779A440C7640" modified="2025-10-08" version="1">MWQPRNSIPDYHHGWKPPVRSSASTRDLNWEPLVEIGSLSLGSECKDSAANAEFRAVTRSFEATMDDLSWAHNSHSPILPKSNQASPIYKNTSAGDEYQRLECASSPVAFFVRKSEDSSRSRELNRGSKPASLPSRDGILIVDYDTLEACGVESGERAVCVDIDRFLPNLIESSSASQSSTAQNLKESRLSSQQGSHFLGLLETQQHGRFNPVAPETSIMHKNESILNESSVRSNLVPSPTYMFALDAARELGEANDGPTHKRLIQGYTSPSPTPAKRHYFQDQTQQTPDKRVKMQQRPFQSPLSNGSFDTTFRPSFGNGQLRIDSDTLPFGASSLRAIPTGLTFGQHMEMVGEEEEDKVLPKPQAQLPPIVSLPRNMTMDLERALEEALDREEQEYQSEHSTWRSHEFGDGEARERLASLKDTWGRECDKATGSDWMEISKAQRSHFGCSHLSTDSGILRRAINTALPQDNPHQLGDEMKGLPSVPKNIFQPSEPTFVVNNTPSQTVSSRKRDRSVHSSGQRHSLVMRQAKSKPEMRSTSMPLTQLTIQVPDRSLFNRSPIMTPLHTGISSAFDVSPPQKSWKEIAQGWGSKLKQRLGRKKTTAATPAVTRMQSVPILGVPRDVADEEVPDKVREEVKKAEVKKVQGRPTQPGLLEDIEEKGGMASSAEASQRASSNTTNGDISPCLSGSMPVFKPTTSMPTHQSETMGFSTPLVPAPVPAIVSRDIVTQEKARDKDEPPRQATPVCDHLTWGLPPIMLIPGEIETLSMTPPVGSSNSGPEANEDMVEEVKVETDASVDSKVSAEAGAETNSEAQIQAQPQVQTTEFSTTTMTKQGCTEEQGQKEDQDQGHEPPQPRLQSSGSCREKAGTPTTFWAGTGGSRLRLPFLRHRTTGIFGADHDCRHGHDDEEVGDGDKKEPMIAKMSGEPVNDTNWLKKMRDVGWLHRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLY6</accession>
    <name>A0ABR3YLY6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Flavin reductase like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006009</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000241">
        <property type="protein sequence ID" value="KAL1888855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050268">
        <property type="entry name" value="NADH-dep_flavin_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30466">
        <property type="entry name" value="FLAVIN REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30466:SF1">
        <property type="entry name" value="FMN REDUCTASE (NADH) RUTF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin reductase like" evidence="2">
        <location>
            <begin position="1"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="184" mass="20260" checksum="56ECDDCF6A3268FA" modified="2025-10-08" version="1">MRRVSHSVVVCTASQPTPNGNIPRAMTMSSFTSLALTPRPLITFNVKAPSSTLDAVIASRSFNIHVLEGDAHGARIAEWFTRGNFQSTLFRAPQSEWQCILRDGEPPVLEGQGILSRVRCSLLSDGESYEKGVVRISDHVVILGEVQEVVTGNLSEDFALTYADSKYRTKGDVIQKHTEVDNKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMX9</accession>
    <name>A0ABR3YMX9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">polynucleotide adenylyltransferase</fullName>
            <ecNumber evidence="2">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_005679</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA polymerase type-B-like family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000207">
        <property type="protein sequence ID" value="KAL1889701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054708">
        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002058">
        <property type="entry name" value="PAP_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045862">
        <property type="entry name" value="Trf4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23092:SF15">
        <property type="entry name" value="INACTIVE NON-CANONICAL POLY(A) RNA POLYMERASE PROTEIN TRF4-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23092">
        <property type="entry name" value="POLY(A) RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03828">
        <property type="entry name" value="PAP_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="7">
        <location>
            <begin position="410"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="PAP-associated" evidence="6">
        <location>
            <begin position="613"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="321"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="739"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="15"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="111"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="129"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="163"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="333"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="741"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="762"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="789"/>
            <end position="802"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="802" mass="88802" checksum="0C07CA8DA3327C57" modified="2025-10-08" version="1">MPSRKNRSSGGGSGSRRQNSDKASSNSSGSSHPTLPARPPSGPRNSDRGNDRDRRNSHKNSSKGDNRQDSFRPPQSDFTFSMPAPGGGHKSFHDRASEFATSNALPRHRNRDGPRNGGRDNWRPRGRGSFVGGRGGRPGWQRFNALERPMLTLDSSAPPISLRDSKDGVRYKTLDEISDDSELEMEMSDSDSDPGAEQSASKKKKEDSDANADAASDDPEEPATKRTRPNEPPSDASTEANKNCVDGANVNSAKAKDAPPLPRWSNPNPYTAIPQPDNNHAKPKDLVKLIRKGRIEEDKSAQANELDELIFFEDSDAENNNTQAVPSSPADGTWTNVSAPTTPTNDLGSRKRTANDIIKPAPRSSKARDTARGMAILNSLYGEWALAPGQKLFTPWIKPAEGDVDITERLSQEVRDFHSYIEPRQSEEAVRQDLIDRLKAGIKRNYALADCEVCCFGSFMSGLYLPTSDMDLVLVSRRHFQGGPAQPRSKSFMYKFRAFLVNNQLSIPDSIQMILSAKVPIVKYVDRQTNLRVDVSFENLSGIDAIATFKQWRDRFPIMPKLVTLIKNFVAIRALNEPVNGGIGGFSVCCLVVSMLQLDPVIRNLNMATDEHIGELLMEFFNLYGNNFDYTKVAIQLNPPAYVPKTHVQSLVYKSTDRLSVIDPNNVSNDISGGSSRFSEIASCFAAAYLTMQERLEAAEKKTKNIKSLLEPILGGNYAHFDDQRQILEETYRNMTTRVMRNNGNGNGYSNSSRSGSSLPARPHPPPPPHKPPPPPPSQSQSRSWQGGRRGERKGDRRRDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN01</accession>
    <name>A0ABR3YN01_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ER lumen protein-retaining receptor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ERD2</name>
        <name evidence="12" type="ORF">Cpir12675_005876</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ERD2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000225">
        <property type="protein sequence ID" value="KAL1889230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000133">
        <property type="entry name" value="ER_ret_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10585">
        <property type="entry name" value="ER LUMEN PROTEIN RETAINING RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00810">
        <property type="entry name" value="ER_lumen_recept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00660">
        <property type="entry name" value="ERLUMENR"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00951">
        <property type="entry name" value="ER_LUMEN_RECEPTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00952">
        <property type="entry name" value="ER_LUMEN_RECEPTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10 11" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1889230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="217" mass="25731" checksum="7E7F2DA4220FCAE3" modified="2025-10-08" version="1">MSLNLFRIVADLSHFMSILIMLHKMRALKSCAGISFKSQVLYLLVYITRYLDLFWTHSPYNFIFKVLFIGCQSYIIYLMTSSYRPTNDPNLDTFRVQYLLGGSLILAILFPHFYSFFEVMWTFSIWLESVAILPQLFMLQRTGEAETITTHYLFALGIYRALYIPNWIWRYMSENPSTYHTDWIAIIAGIVQTVLYSDFFWVYYTRVLQGKKFKLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN02</accession>
    <name>A0ABR3YN02_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_005800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000217">
        <property type="protein sequence ID" value="KAL1889400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1889400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="95" mass="11123" checksum="046719F4C173ECB4" modified="2025-10-08" version="1">MRAKHIRHKFNIKELQYFQLSQVQCAVWTEVYLHGYLAFFGQFADVANICCEDFPPVTTPEELEDQIYIREPLTFIFDDPGRQQIGLLNPLTAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP20</accession>
    <name>A0ABR3YP20_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005683</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000208">
        <property type="protein sequence ID" value="KAL1889679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050910">
        <property type="entry name" value="JMJD6_ArgDemeth/LysHydrox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480">
        <property type="entry name" value="ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480:SF21">
        <property type="entry name" value="JMJC DOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="1">
        <location>
            <begin position="86"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="327" mass="37538" checksum="5F47F38EF3EBC916" modified="2025-10-08" version="1">METLPYTEFAEQWGEKPFVLTNYTRHWPAMKEWTIDSLLAKYGDVVFRAECVDWDFKSYVRYMRNTQDESPLYLFDKRFAEKMNVTIGTDPSNMYSKPEVFGPDLFEVLGDKRPAHRWLIIGPARSGSTFHKDPNATSAWNSVVQGSKYWIMFPPNVQVPGVYVSEDSSEVTSPLSIAEWLLEFHAEARQMPECVEGICHAGEILHVPSGWWHLVVNLEDGIALTQNFVPRTKNLHHLVEALFFLKDKADQVSGFKDDVVNPYDLLVERLGTSFPEVLQEGMQFYEKKLAGKKRKWDEAIAAKTEEEKASGFSFKFGVDESSEEEDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP97</accession>
    <name>A0ABR3YP97_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Deacetylase sirtuin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_005500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000191">
        <property type="protein sequence ID" value="KAL1890184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF15">
        <property type="entry name" value="NAD-DEPENDENT HISTONE DEACETYLASE HST4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="6">
        <location>
            <begin position="234"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="772"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="824"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1044"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1112"/>
            <end position="1234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="60"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="72"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="198"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="772"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="785"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="824"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="837"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="865"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="882"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="932"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="943"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="982"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="994"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1006"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1054"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1156"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1187"/>
            <end position="1207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1209"/>
            <end position="1222"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="378"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="386"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="389"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="408"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="411"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1890184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1234" mass="130272" checksum="E83716F5B05F3176" modified="2025-10-08" version="1">MNYIGESPSPPPPSTSGVLQRHPPSPTLKDTIDNKNSTQAKRATIIKLKITSVPSKTLSQDTRTQAQTQTTISKSPPQSLVHTKSENTWKILLKAPPSPTTSLKSTKRPRTALPDSRPQTSTAKRRKLNITSESDDMRRNAPRSAKDASATAAKNVPTRSKSIRASTAIKAAEPKRPVATTGTDKVAATKTPESISSTKPATAKTTTTKGLKLRTTEYLDLDEVCKTAAEDGVPNPGAEHLETLMNALRKKKKIVVIAGAGISVSAGIPDFRSGHGLFKTLKSEHKLKVSGKQLFDASVYKDNNMTESFHAMVRKLSDMVKEAKPTPFHHMLASLAEEGRLLRLYTQNIDCIDTGLEPLASNVPLNQKGPWPRTIQLHGSVRHMACSKCGFLGELQSELFDGPIPPECAQCLEEELVRMNFARKRSQGVGKLRPRIVLYNEGNPDEEAIGAVSLADIRARPDAVIVVGTTMKIPGLKRLVRELCAVTRDRRDGFTAWINLEPEPQTAEFRDCWDLVVKAKCDDVATLLSLPRWDEYRAWAANGSSAIIPTAADQEALRCSRLEVALNGTAQKKGKGKAKASNEGKAQIKTECTLDSKLGCVAPASNAKKTAAALKGAIDIEAAEVKSSGQSGFSSTALTPVAAIAVESDLAAQESRLLQQQAVKKEEPEGHDHNRDGAADASEEGLIVHRLRGVKLSSGGDDGIEAVLTAKASATTAVTVIPIPIPTTATVTNTGACLDGDGVPGGQSFADDTTNTDYNQVINGKISIYSSSNSSSSGISISASHTPRPSKTTSSASDNKTVTCYAAATATTASATAVAAGTRSMTSAGSFQPQPRAKPKATRKKKSSFVASSQRNVISEEPAAESSQLDSAVSSPSEFALTSAPSSTSISTSTFNANSNSTSTSTSTSTPTSTSITSASTSAAPATTIRKQSTRSTHKQSKLGFSSTKASLVATVSSSTKKSDPDVDSILPCDSTSSSAPSRRRSIKHRAAKTKAAAVASTSSKPKPDVVTRSKDSTITTFVTTVTKSSALSRKAVSEFKLPRPIKITPPSPQTQLQTQSRSPLSAIALPKTYEPTYTPESPTSLCDIVSSPASNFGSALSPDKSSVACDAYDSESEAPSDLDCHTPEASMTMSSKDESSKKRAKKYGPTFKVQPMPPPEIPVIPDPPFKMSENGSNKPYKCLTPSTAAAAAAASASAGSSATMGSDFSKQVSTPGDTISPSKVPRGMESLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP99</accession>
    <name>A0ABR3YP99_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005654</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000205">
        <property type="protein sequence ID" value="KAL1889769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42088">
        <property type="entry name" value="YALI0F10131P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42088:SF1">
        <property type="entry name" value="YALI0F10131P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="522"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="664"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="730" mass="79281" checksum="3AFE0DD5FFBA81EE" modified="2025-10-08" version="1">MVHPNFGGEAYRLGPRVPSFDKDGIPISSHVLFESAPQINARDSSDSDSICQGNNKSSYCEKPYQTKNLRLPIALGIAVPLVCAAIACVWFWNKNRLRERREDQDAAALNFDYGMENGPKNSKNGATPSAGGTGEKGGLHRGQISMDMNLSSPYLLPPKIHESRESLNSLTRTIDTKADPYRPITQYTNSDVGSLRSYRRDPNDAASVYAPSTRRNTRTSNMPATPSAAVTKDPFDIPPTPHSAKFNHRSSQNTTATPPENPFASPHDENHAGQKRASSTLYPDDNGKDTGLDFGLPKDIQEPPAAMLHGDHGNSSNGSWELAAANGPSNYDMPEHSHHLAVELPNQPAYSDGGNQASAQLSITIPPASVGTVSHDIPQVAVPYPEDDNTTQPTYPDDMYDDEPRGRIVRRSIDLGAGGNDGGLLSAPANEKKRISIGFRPLPPDEIMDNEDPEYRANRIRSFYKEYFEDYTRGGDAPDVPSLPRQYQNGGGNYYEDYDPSYLGDTYLDTKTNAFVMPYAQPVTRRAMTPPPTRGPQMRGPPRFRTDSALGPRSGSSASQMRPGSSASARPRKRGPPPAALSTLPNPAKLGTDTLTLLSTTDFAPPSSMADRVAGRSQSPTLEKIQYAPKIPVSTPIVGVFDELASVPSPHMLKSTVTMSNLDFAPPRRFKDQDDMSDAGSIRSNRSGLSAIQTQAIRSGAGRISKLPEDMVFTPTDLSSALKPSWGMRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ24</accession>
    <name>A0ABR3YQ24_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7707 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_005392</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000183">
        <property type="protein sequence ID" value="KAL1890468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056124">
        <property type="entry name" value="DUF7707"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38118:SF4">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38118">
        <property type="entry name" value="ANCHORED CELL WALL PROTEIN 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24808">
        <property type="entry name" value="DUF7707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046854067" description="DUF7707 domain-containing protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7707" evidence="3">
        <location>
            <begin position="26"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="194" mass="19061" checksum="A52FADF109C09542" modified="2025-10-08" version="1">MRACTVLAAFAAGAHAAVNLTYGNTTVNIGSIDASQKSAYCRGQRNTCEQLCSDGTDANTCDTNTLDYTCTCSDGEAPANLSSFSASMDAYLCEAAYSQCISASTGDATGQKACKTNIEDKCGKKDVSEAASSSSTTAATTLSTATATGTDSGSTGTGSITTVAPTTTTTVASGASAAVVGAGAFAAAILAAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQX4</accession>
    <name>A0ABR3YQX4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="3">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_005457</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cyclophilin-type PPIase family. PPIase D subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000187">
        <property type="protein sequence ID" value="KAL1890287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01926">
        <property type="entry name" value="cyclophilin_ABH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="7">
        <location>
            <begin position="10"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="177"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="373" mass="40159" checksum="0AB91D92A01BD083" modified="2025-10-08" version="1">MTEDSRPRVFFDISVDGEAVGRIVIRLYSDIVPKTTENFRALCTGEKGVDSESGKPLCYKGSIFHRVIKDFMIQGGDFTKGNGTGGKSIYGETFDDESFAKTHDRPFLLSMANAGPGTNGSQFFITTKKEGCSHLDNKHVVFGEVIAGKSIVRSIEGSHTDGSDRPTKPVEIVDCGELSADEPTTGSGNVADPYGDKYSDYPEDNDGEELKAGEGFNVASECKGFGGAAFKAGDIAAGISKYQKGLRYLAEDPTDLDNASEDVRASFDLLRVQLNNNLALLLSKKEKWNEAKKASSAALGVAGIKDADKAKALFRRALAHKALKDSESALEDLVAANKLAPTDAAIINELNATRAKIAAYNEKRKAAYRKLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRF7</accession>
    <name>A0ABR3YRF7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005380</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000182">
        <property type="protein sequence ID" value="KAL1890486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013952">
        <property type="entry name" value="DUF1776_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43313:SF1">
        <property type="entry name" value="3BETA-HYDROXYSTEROID DEHYDROGENASE DHS-16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43313">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08643">
        <property type="entry name" value="DUF1776"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="39"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="542"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="698" mass="76623" checksum="58CC57D9730E89C5" modified="2025-10-08" version="1">MAHRKDIWTAEEYQSSASFVPKLATKVVQWLDVQTDDVVLDLGCGDGILDEQFIRVLRQGSGRLIGLDSSVAMIEAARKLVPDKNASFEVADCSKLDALPHITTGIFTKVFSNAAMHWILSPTSTRTSFFRGVREATAPGGLFVFEMGGLGNISEMRTAILMAAARHIGLQAAISIDPWFFPDEAYVTHMLQSEVGGFLVLDVEREWRPTPADAAGVDGWVQNLPGQLQHYTNNVAEFVDKQIDFAAGTVRNSLSSVDWLPSSIRPALPTPPPEPVIPQSMLESAQTWVVRNRVLIGITVIFTGTIAYKTYRSTASARKIRRARRAKNNGRVEVVVVAGSPTLPLTRALSLDLERKGFIVYVVCNGPDDELLLQRMARPDIRPLGIDITDPPRAGVAIERFANYLQSRHSPGPTVTPNYLALKSVILIPSVSYQTSPIATIPPSSFADLFNTHLLHPILTIQAFLPLLTARLTPAGEEWAPPKVMVFTPSIISSINPPFHAPEATVCSALSAFTEVLAAELRPLSIPVTHIQLGTFDFSSFSPSRSSQHPQGLLPSADSDATSWPENARHAYGRNYVTSSASAISGGRIRGLRGSSLRYLHNAVFDVIDGSVTSDVVRIGLGANVYGFVGRWVPRSLVTWMMGVRKVDELHHWQNTHELVTYQNDEEMMGDEDGDEMTESKDFIAVSHEADEPRNVWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRV0</accession>
    <name>A0ABR3YRV0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_005232</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000171">
        <property type="protein sequence ID" value="KAL1890807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1890807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="221" mass="24544" checksum="5808956D4EB8DE6F" modified="2025-10-08" version="1">MQPVLMSPCRFGIVRGPRSCHEQQTQGMQCPRGFLCSTCRQPPRPNGFEQIAKIVTEIRRHQLRPECRPRHSRFVTLDNQLTRFDNNHEKGLPTPSLQGLCATSATSDAPVFDMDITNKTASPPQWLTNYLHGLETGKISWSGKRSTSLSSITSTDNSPVEPDFKVDLQPILASKPESLMEPRAQTTATNPSINATGAKNCMTSTRIKGKFFLILEFISVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRV3</accession>
    <name>A0ABR3YRV3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">VanZ-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005333</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000179">
        <property type="protein sequence ID" value="KAL1890580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF037970">
        <property type="entry name" value="vanZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28008">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28008:SF1">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="203" mass="22758" checksum="2EBA996B71A5E660" modified="2025-10-08" version="1">MRIRPQFAAAFFVLGLIATYAGLTPLNFDSYVNNKFLHLTTFFVLTLTFYWIVDTHRRRALNLTLVVCTASLGVGAEFVQGVFSTSRNFDISYIVANVIGSGGAVALCSWYHGRMLDRRRQRRNYDVVPGEDDEDLELGEDHETGVIDNADADSPVVSNLEQQVDNWDENAEDNWDDEEEDDVGLGTVSGAKTEEPIVKKRTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS80</accession>
    <name>A0ABR3YS80_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Alpha-1,3-glucosyltransferase</fullName>
            <ecNumber evidence="10">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ALG6</name>
        <name evidence="12" type="ORF">Cpir12675_005229</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2 10">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the ALG6/ALG8 glucosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="10"/>
    <dbReference type="EMBL" id="JAWDJO010000171">
        <property type="protein sequence ID" value="KAL1890804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042281">
        <property type="term" value="F:dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004856">
        <property type="entry name" value="Glyco_trans_ALG6/ALG8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12413">
        <property type="entry name" value="DOLICHYL GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12413:SF1">
        <property type="entry name" value="DOLICHYL PYROPHOSPHATE MAN9GLCNAC2 ALPHA-1,3-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03155">
        <property type="entry name" value="Alg6_Alg8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 10 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="243"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="300"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="409"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="433"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="503"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="537"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="577"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="16"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1890804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="614" mass="67796" checksum="9908FB42851F3E89" modified="2025-10-08" version="1">MASSPASSKPRRRLKGSSPSPSPSSQRPALSSATSHSKFPSTNTSSSSSSSSDTYGKAPTFPLASFFWPARSGITSWEILPLTLMAAGLFRLAVGLWGYSGFQKPPMFGDYEAQRHWMELTLHLPISQWYFHDLKWWGLDYPPLTAYHSWLCGAIGNAIDPSWFALFSSRGLHDASLKVFMRATVLVSEYLVYVPALVVFINRYSHLSNVTVWSSSVALAAIMLQPATILIDHAHFQYNTVMLGFVLASMSSMLANRYLWAAVFFVAALGFKQMALYYALPVFSFLLGNCVFPAINPGRLFSIAAVTAVAFALLVLPIALGALHDAAAGLDARPDFDGPPVPLPIFTFLDDMLDREAAYYPVVQQLVQMIHRVFPFARGLFEDKVANFWCAANLVVKLKHLPPALLQKASLLATLASILPANIVLFLYPRKTLLPYAFAASAWGFFLFSYQVHEKSVLLPLMPMTLLLAGKHGLRADTRAWVGFANILGAWTLFPLLKRVDLGMPYAVMTLVWAYLVGVPVPAIFEHTLEHGQQSRGWLRLAVNTMHGLFYIFILLWHGVEMFVEPPPDKPDLWTVANVGVGAVGFGICYLWCMARLVVEAGLFGGKTAKTKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSC4</accession>
    <name>A0ABR3YSC4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005472</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000189">
        <property type="protein sequence ID" value="KAL1890254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF118">
        <property type="entry name" value="CYCLIN, HYPOTHETICAL (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="667"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="726"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="918"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="279"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="319"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="367"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="400"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="674"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="735"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="751"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="961"/>
            <end position="992"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1094" mass="114556" checksum="6C8195E3862C580E" modified="2025-10-08" version="1">MQTISTLIRTIATPRLSLQPLQTLGQPSLSLLLYSLPLAATSTASDSTASDAAATAIAATTAATAAALTAPAAIIASVVPAAAVSAVHGPRSTRLGPDPSVVRFPISAAHFVSSHTRSTLPTIAAPWLRVPQSPPPDMSIMGTVYHSGLPYGVGAYAATATAAPFPSYLNATAAANTPSNTTANTAANTAAASASSFSSSVSGSGSGSASDSKAASSALLDIASYPSSSSVSGSSSFASYTSSLGTAPSTSGSAFGSLDSYKVHSQSHPRSSYTHIPISSSSSSSTPPTTTTLSASSSSASLASALEAPPAAAEDEQPKPAVAPKASAAPTTAALAPPVLPSTAVDSASTMYAIGSGSLRTHEHQQQHQQLQQHQQQQAEQQRHQPLAPVSASTNDHLHQQSQQHSSDLASSRMHPSFQSAADPQPSSSSAIATVTVNTTAAAMSTASAAPVASSGAEPKKTGLELHSMALPACISPNGGSLSDFVAQMTCFMIQEPWKIVADACQYTSGSPLPRQRLVPEAIAKPELLKWTQNILATTQVTQNVVLLALLLIYRLKRSNQHLKGHYGSAYRLLTIALMLGNKFLDDNTYTNKTWADVSSISVHEIHHMEVEFLSNMRYSLFVREQQWSAWLKNMANMKAYYDEAARRISSPDPNVLMAAQTYLPPQPLHAHSSHSPSRLSTAYIPSSSGQSHVQLPHTITNASASVNAAESMVYHPELSPSLSAGALSRKRHYPEHDPQSDARKSRRMSSSRTLSISPSGQMCMSHTANVPLSLGSSVAPMDPISYASTFNPPASRDSRRLTLPHLTVNTDTNPIAAAPVPQPHSAFVATTVPGSNNNNNSQPVFGNLAARTVSSSLPPLASGSRSIAGNSVVNPHPGSSYGGVPPQNLVAMSISQPSVSSHLSQSAAQAYLPPSTTQLSSAGYVTPTKRHSPGTLGRYGFSPHGTNPDIFMNHQGRIPSHSQNSGLAHSHNMATSMPRSPLSPSVQSATLRSAVPHSHPHGVSVSTPLDQTPGAGHQRSPYPTLSPIAYLSDRSSPYRPVRTVKTLMYPPGSTSLSEYHLTPQAITPNSMHWHRVGRPNDIRSGIVPEYRHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSW8</accession>
    <name>A0ABR3YSW8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SAGA complex subunit Sgf73</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sgf73</name>
        <name evidence="3" type="ORF">Cpir12675_004952</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000153">
        <property type="protein sequence ID" value="KAL1891475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.670">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013243">
        <property type="entry name" value="SCA7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037804">
        <property type="entry name" value="SGF73"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47805">
        <property type="entry name" value="SAGA-ASSOCIATED FACTOR 73"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47805:SF1">
        <property type="entry name" value="SAGA-ASSOCIATED FACTOR 73"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08313">
        <property type="entry name" value="SCA7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51505">
        <property type="entry name" value="SCA7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCA7" evidence="2">
        <location>
            <begin position="190"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="384" mass="42387" checksum="A850FFB109C2EBB3" modified="2025-10-08" version="1">MKPMKRGVLKLRKSQPKPKTASWQEDEKKVKAFEAAMAALPRPETNQIDPMIRDSFSLARLVEEGPDLQLCKHCKKGIYRTNASHHINMCLKLKKEKAQRKKEAREARERAKEAAKEGGKRDDDDKENDSSDGEDDIPADKKGNAGKTTRKGAKKTDLDSSRASKKRKADGEAEKGPKSKKKKEEPKPKVAKPKGPVDVERQCGVLLPNGMPCARSLTCKSHSMGAKRAVAGRSLPYDMLLAAYQKKNQAKQQKAAMDANAPIEEDETGPVDPEEEFNSVMNGLSQWNPRPVVEQPVFEPIKREYSRSRLYEQLMIATNGMKKNIFKVVGFGAQKLPPDHNISQADGEDAVGEPDSGVSYTSQILPPSTGTAGTTARKLSTVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTH0</accession>
    <name>A0ABR3YTH0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mediator of RNA polymerase II transcription subunit 10</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Mediator complex subunit 10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">NUT2</name>
        <name evidence="6" type="synonym">MED10</name>
        <name evidence="7" type="ORF">Cpir12675_004869</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the Mediator complex subunit 10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000148">
        <property type="protein sequence ID" value="KAL1891683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019145">
        <property type="entry name" value="Mediator_Med10"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09748">
        <property type="entry name" value="Med10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0010">Activator</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 6" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1891683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="171" mass="18629" checksum="D98EF7D098431325" modified="2025-10-08" version="1">MTTSTNPLHDKLEDQIRNVVEDMFKIMVITANYDAGGRPSKEILATSIKTLDASLQQVYQTASHNANALPTVPPELVQYVEGGRNPEIYTREFVELVHRGNQVMRGKMHAFAQFRDVLADHICVSMPELRDDVLAVVEATGGRAPPFNPLLCPGTAGTQANGQTPGAENGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV93</accession>
    <name>A0ABR3YV93_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000145">
        <property type="protein sequence ID" value="KAL1891806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="437"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="329"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="487"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="518"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="592"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="625"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="637"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="985" mass="109333" checksum="0C08D60ED75B3B4D" modified="2025-10-08" version="1">MHSSSPSNHRPSSPPSHLDASNNHHSSAYSSVYSYSYSGSRQQSANSRSPSPHRRGRDEDRDRDYGSRRESSGPGNYSHSYSFAQGRSSRENEKFRLQERDPSPTPPPPPPRTSQPKTFPVSYNTTRKSAIPPPPPPSCEDEDVSLAREHDSPIVSQDPEIYGICRGELQQDALMVENEDHVPKFMPDVIVQQHESASLKTEAGRQHNPNIFESTKAFVLLSNPGSSPPQSEQKANLGAFRESHSKTPNREQQGYNSPSSRPAIIEKDGRNKEPDEGRAIHDDEDCDWGRNFERDRRRYSSSYSLHGKSSRLDLRSDLKNDCHETTTNTFSTSYSNSNSSHNLQPTASSSGVSSAASYKDSDYHYDRHKKHRSPSINANGSGSQDYREEYRLPSAKLANEYTTPSGPKLFGPKPEPGRSSDRTPEVLRYKTDYSLPPEIHTNVAGTNRGSYSYHSTKGSPVRNSVRDHECDFTPPAPPVSIPVRPKSASDRRRASVIIHEEMPRVSGPRNSEPHIRTGSRAGYGSSAGLASSPMSPPYSSRDHPLQIPTAHFARDHLGSVGSDSRATNAPYPEDEDLPDVMARSGSAHLGDGTRSGSRGTRSKYPSPSPSPYSVSGATGPAGPRSLQQSATPTSSLRRAEPALVHETDNAPARSLDMIPLNSSVGAWRRYLEEPARYGLPSIPVCHVSPSQLRDVAFMTLRDVPDFDICVPCYKVVFASGPYKNQFVESVKPVYAGSSRCCDFGAVPWFQLGWIMALKRREARIGDIYERIMKHVLEKTPSCSSPGNLLYMYTLRNQWANETNILPDFAICPRCMEGVFALLPNVFQSQLCVQVKPTDGQECALRHILGSISSRFTNIFNCVEVCSDRGTISSHGPDGRKLVEDLRQLVGFAECSGSNSPRYNEDWYVIAELADLTMCGDCYHTYIKPLKHSELGKRLAADKHHRAFGTCEINSSRMKSMLSVALQTRDFATLRRDIYASRRPEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVN9</accession>
    <name>A0ABR3YVN9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosome assembly factor mrt4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MRT4</name>
        <name evidence="8" type="ORF">Cpir12675_004789</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 6">Associates with the pre-60S ribosomal particle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000144">
        <property type="protein sequence ID" value="KAL1891900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05796">
        <property type="entry name" value="Ribosomal_P0_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.105.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033867">
        <property type="entry name" value="Mrt4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040637">
        <property type="entry name" value="Ribosomal_uL10-like_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043164">
        <property type="entry name" value="Ribosomal_uL10-like_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051742">
        <property type="entry name" value="Ribosome_Assembly_uL10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45841:SF1">
        <property type="entry name" value="MRNA TURNOVER PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45841">
        <property type="entry name" value="MRNA TURNOVER PROTEIN 4 MRTO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17777">
        <property type="entry name" value="RL10P_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL10-like insertion" evidence="7">
        <location>
            <begin position="125"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1891900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="250" mass="27443" checksum="6A4C5098A49D23FF" modified="2025-10-08" version="1">MPKSRRNKSISLTQVDKKGREHKDKLFANVREAVGEYQNCFVFSIDNSRNNYLKTVRQELSDSAIFFGKSKLMAKALGLTPEEAQAPGLELLTPHIHGQVGLLFTNRPAADVTSYLSSINEADFARAGTVASRTFVIPAGVVYSTAGEVPAEHDVILEHTLEPELRKLGVPTRMVRGKIVLGEEDGSTEDYVVCKEGQVLDSRQTRLLKMFSAPISQFRIRVIAYWSAATSNVTEVEPLTAGEAAASESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVW7</accession>
    <name>A0ABR3YVW7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein SABRE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">FMP27</name>
        <name evidence="6" type="ORF">Cpir12675_004772</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000143">
        <property type="protein sequence ID" value="KAL1891913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019441">
        <property type="entry name" value="FMP27/BLTP2/Hobbit_GFWDK_RBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019415">
        <property type="entry name" value="FMP27_SW_RBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019449">
        <property type="entry name" value="FMP27_WPPW_RBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045167">
        <property type="entry name" value="Hobbit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15678">
        <property type="entry name" value="ANTIGEN MLAA-22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15678:SF6">
        <property type="entry name" value="BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10344">
        <property type="entry name" value="Hobbit"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01214">
        <property type="entry name" value="Fmp27_GFWDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01215">
        <property type="entry name" value="Fmp27_SW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01216">
        <property type="entry name" value="Fmp27_WPPW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="FMP27 SW motif-containing RBG unit" evidence="4">
        <location>
            <begin position="1231"/>
            <end position="1333"/>
        </location>
    </feature>
    <feature type="domain" description="FMP27/BLTP2/Hobbit GFWDK motif-containing RBG unit" evidence="3">
        <location>
            <begin position="1351"/>
            <end position="1511"/>
        </location>
    </feature>
    <feature type="domain" description="FMP27 WPPW motif-containing RBG unit" evidence="5">
        <location>
            <begin position="1763"/>
            <end position="2421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="787"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1163"/>
            <end position="1223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1819"/>
            <end position="1865"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2021"/>
            <end position="2058"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2190"/>
            <end position="2278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2458"/>
            <end position="2539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2825"/>
            <end position="2896"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2910"/>
            <end position="3063"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3220"/>
            <end position="3274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3450"/>
            <end position="3469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1193"/>
            <end position="1205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2021"/>
            <end position="2031"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2205"/>
            <end position="2217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2226"/>
            <end position="2247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2248"/>
            <end position="2273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2470"/>
            <end position="2488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2495"/>
            <end position="2515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="2844"/>
            <end position="2868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2876"/>
            <end position="2896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="2922"/>
            <end position="2942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2948"/>
            <end position="2962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="3003"/>
            <end position="3022"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="3050"/>
            <end position="3059"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="3233"/>
            <end position="3250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="3258"/>
            <end position="3273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="3523" mass="390008" checksum="B20525073D08DEBB" modified="2025-10-08" version="1">MALFNPSFVFGVAVLLYLCSLVFFAILRILTGVSIQRLGFSSLRRISYTPRDGIRIDIRGLGLNLHRPTFAQPTWLSIVVDELAITINRTQLENSARRGDDCDSSTSDAEEDVASSLPADSLLAKTSPNYITIPSSTPTITRNGDTLNSPIENDDPFNPPIATPAESADAGNNPGSTTAPASPPSPKPSRTLEMLTKFKDRIKKLHRNIKWLRMVDFVATNSSISMVGVGSIQCGSFNMGVDTRSRLVDRTWFFNAGADQSAKKKKKDQAEWNIALRSVLFTAEGKESIDIVDNITLNIHGFLIDSQDGLRNASIALKLGRVYIPWDDISLSLANLKKMRKGEEVATPPPTFIGGNAGIKADSAVSSGLDEAFQPAPLLKPPQRIPTFNSNVDNDLLQRVSDSKELIMSILRGIKEVQFAVSYIAVSKQAEADYPGSPPLTMTASMKEVGIDLHRLNSKSPAHRMYFDGNDIAHEALAATLSISVGINDGSGKHQRLVYIPMATTTMKTTLPSKTVELVKRGSPEERNTNILFANSVITSPSLDLSPHQIPLLIRLLKPKPKRRVMQQLETPDPQKHHLISRLLPKANIKFSMHEPVMRISLSPLKKTEDSDDSDLIISSISSISLEIESFHSAVQELHYSLASTMRLQTHKLYYQTASGERLDLTQTESFDMRIQLSAAPDVFVVVNGSLKTSTIKMLRPEFIEGLRQIVHQLHQDVQGDKKKSKRPPTKQNFLRALPSWLLHVQIQMSDVSMEVAGTDVKVSDDTRGMSVQLDSLTTEYRAQRLDSLQRHNSRRRTRSRSMTPDADILKTPLSPTPRKKMCLVPGDGRKLGFHVKGLEVFIIESISHTEVEPFVRCPRAEVTLSSMSDTHGPVFHLQANMRSVLINWSLYRHYAMGVALMVLRKAFMPMPSFSSDEEPLLAESKAPTISSEVEYLSPPQSPSSLSLSRGQLQGASMTELFTADVNVSLVQIKATMPHEPRMLLQVFGLEIGSHRWSAPYLTSCLIRLCVNSPRISTVWSRVLSIKAARLDYRQSRKKVPSGGYVADKLIELYAESIRLAIPYEVLLNRITDNLVNTMKSVQQLHYRFKTDGEKQFPFDKGPVGPKVPPRISIRTRAFLFEIEDGAFEWKLGMIYRAGLVEQQQRLAREEAFRLKTKIVQEESRKTNRTKHKRGQASAGTLDMDKEALRNRSNSHHHHGGHSRNHGPSYDPENNMPCLSNSASPRLKLDEARAKLDTLHASSWKKRIDRACAIAEENVREFRSAAWGPSNTPDDIEEAESILEVPARAALASAYFTDLQITIDKPSFPLKDLPKFMHSVGKGIPQDTQYSLLVPLHINIDTSEARISLRDYPLPFIHVPPLEASQSTKKSAFSLSTDFVIAEEYRGPESLRPLRIDIIKPNVMDFEGAKTYGYHLEIRRTIGAVKTYSNMKVDVNTSLPTRITWGPCYQPAIQDMMTVIETFTKPQLDPSERVGFWDKIRLSFHSRIHIAWRGDGDVLLSLKGTRDPYCLMGTGAGFLMCWRNDVRLNLNAEDDPKRFMTVNSGEYVLAIPDYAQLVRAMMRRDRDGQDDNPQIDYDDNGPVVSQDFQKVVMKLGGKVQWMIGLVFEQAIVNGKRSFDFKPHYNVILREPSKAKPDRVMGLPYDAFRGFRSTHIHLSIAVRAPVDRDWMAATPQPSRSYNTVHMTPRFFTHFYQWLSLFGGGMSLPIRQGKLWPGRDKGSKKFGRHVATLKYNLLLAPLFLTHIYKHKDPDTDLEDGSMATGIKVRFDSFMLDLHQRREEFNTQDHGRKTQSRTSGIKIHAAQLDLVSTDIRAVSATMRSPGRNSGLNLSEMPAMGVDDDASSSMKQDVSDKEDDGPDNSRFTIPDNDMTWIDVDDFVELDWILPSERNLDTKILPLAFSPRLTYFRQTDIGGVIAGDPERTSPFGNEPTHFCIMSYDDDPRRVQQRLVNDRLSRLQGQMDNHALAMDEAEVGAIKRDHDVESMAQLEMLRRQSEIFLHKKAFLEHMLLGLTVRAASVSGTSFDSNSNSPRPKADDNCSSSSSFSSGNMPPGASIKLPTGAEFESDYNNRFVIHNLHFKWNNELRNIVLRYFDQVSLRRGLVYYLSRPAVKFILDIVEEQERAKFNTPKRSTTAKSYVAGNKPSNSHSGILVYGPQGNVSGGRDTDQSSIPPEADEAIRKLMEDGRRFIGDMPVDSSSNCSSSYNLGHNQGHNHNMSSSSIGSSRDMDLGRGASSERERDRDRDRGSSSATSTSINASINGSNSGLNPSLNPRVRARRDSSTNSFIFGSNDAENGAASCSSDLSSGISAGFMPKKSYHVRLIAPQIQLQSDQNQKNVVLLTSKGMELKVVEVMDKKRLSDNVSGLVQRRFQVNMDSTQFFVTHRKWFQNSQLVAMGAYGGSSYGAPLGSMWPPWVPMEVMFDFETDPFGFKRVVQKTSGMMRYDKFNTLRLKYNDKINTENSSGGQGSSSGNSNSNNANSNGNSVSNTVDIDYSNVTSNPNPSSHHNLNSHANPDSAAASTSDPRAAPPANQASKEPTDSRMDYLWVDFPQARALCNSSQYYAMYVIVLDLLMYNEPTEKIRNERLEKIMLASDFSDLSGIPETVSKMQHRIRQLEHIRQHFQTFPRGSTGGPRNDGVSANSLRKDRMTLSNELAACEEELFFMMKAITSSQRKYNTYGAAQTSTPLLRWSITARDIVWHLVRDTNDPLVELQLRDVEYHRTDSSDGSHFNLIQVGKILGLNLLPDALYPEIISPYYDAKHAPLFQGQKMIQVYWYMLEAIAGITVMEDFEVNLFPMRIQLERDVGKKLLEYIFPGMNDGESPKDVSPFILKRHGGDGSSVASDEDEDDEDDDHDHDDTDDDTGTDGETDHHDSSLPSATFSNGLSDMGSPSSTSLEMRLRPTLTSLPRAHASSAQATSDHHHRTHRGPHFSHQGHRRRQKSVSIRTGSEGTSSSTKTTKTLLRAHTLRIPTKKHSSESLRSTTPSLSRPGLTRPPPIRLTSSSSAVAVHGGGASSAASVVPGLVTSSNDVSGKAGRFGLRRRETSARPSRRRRRRRGSHSDDVTKMMARANKFMAFAHINVPSVLLCLSYKGKDARNFEDVHDLVFRMPQIEWHNKTWSNLDLVEALKKAVIRALISHTGAIIGNKLRHLPTAAASQVKGVAHVSSSVILSQAAVSAAKSPSIHSNSGQNLSLSAASVRYTESFSNISDDSASVFGANSTVDFSRSPPPSIRSSNKSIRPRSNSRSSSVHSGCTTQSQASNSNSSVAANSSFGPSLKPNANAHSSSINSSPIGAGFASLATSYNEIAPSRNLRSAHEIRPTSQGGLSLFTSRMPAAGDDAWQRPVTSASHLDTPTGNTVNPFAPMNTTIITAGTASSASSVSGIGASNNQSHGFGFGGEGKRKKFRDKLSSFSPFAKLGHHRDSTVHGPPTPSSSGVAGFIPEFEGSEAMARQESGSSSRTIGPANGASRLLSVPTAVPAAVAMGNIQVTAHDNGHEDMYIVEDEGLHENGAQLAKSQSHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVZ4</accession>
    <name>A0ABR3YVZ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_004542</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000131">
        <property type="protein sequence ID" value="KAL1892428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1892428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="471" mass="51505" checksum="E176A188A46FD2A3" modified="2025-10-08" version="1">MASLSPSRREALQLTDVIANSLVLDHILPYLSAYERLRLASTNKYNRWLLLDNTHFFRHLDMGTMKTINFKVKEEEINEFDPNAQIRDHLTEDEFMSGPIRGIFSSLRRADFLRNIQTLILDGLPVTADVCYEILTSPDFNVRILSIRGATSLNERKLCDALREACRPTRSKSTPRLKGLYVFGAPDSAVPSGTTADIWYHKRGQVIQRNVISDWGGVLQDCRDVLAFDSVLCKGPAHINSPVYGCYNMSVTFLSSSSSPSSSQWAVATYSLGGCAGCGSAPEGLTYCDRYTPTSDMPMISPPPLLTSSVRAASMLCAEAIANSGNPRSPCFVARCESCVRGRMCRCCNKWYCEDCYPVLQSRPHTELQTQTIGSPTIPPVLSPLSLSPDSISSVLSVGSAMSGLSISSSVSSTSLSDDAASALPKNPIARQCIECGFNCLDCFATTQKRCDGCGDSYCLKHHEGSSSHYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW26</accession>
    <name>A0ABR3YW26_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_004469</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000127">
        <property type="protein sequence ID" value="KAL1892581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF213">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045595479" description="Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="381"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="670" mass="72362" checksum="B537316E1CF27FFE" modified="2025-10-08" version="1">MSSSLSNILLFGFYAASALSAAVNTGHPNGQGGGRRSPFVTKDQLLPAYDYVVVGSGPGGGPLASRLARAGKKVLLIEAGDDRGDSSLYQVPGFQINVGEDPETRWSYFVDHYSDPAQQDLDSKQAYLVGEDEYVISKAECDRLGTNPPRAGILYPRASTLGGCASHNAMITTTPMRRDWNSIAQTTGDGSWDAVKMRNYFARLERNTYMPAGSEGHGFDGWLSTSLTNLDMVLPDQAIMNILTGAARTFGIETAYPPAVELFAPILAQDINNASATRDNAVGMFQVPMATKEGVRNGPRDFIMETATATKQGGGRLYHLDILVNTLATKIKFDTSKPKPRATGVDFISGKSLYSADPRFNGEAGVSGSVKASKEVIISAGAFNTPQLLKLSGVGPKQELASFGIKTLVDLPGVGENMQDRYEVTMNWKASEPFQIIQNCTFNREGDPCLATWKQGSTAADRGIYHSNGAPLGLILKSQQTAADEEPDLFLFGGAVNFRGYYPGYSVNTTADNQHWTWGVLKARSRNHAGTVKLRSANPRDMPSINFNSFSGSEGDADAKAVVEALDFVRSMYSNLEPGFGNFTEVWPGPQVTDLEEFVRNEAWGHHACCTAKIGADNDAMAVLDSEFRVRGTNGLRVVDASIFPDIPNYFITTSIYMASEKAADVILKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWK1</accession>
    <name>A0ABR3YWK1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nucleolar protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">NOP15</name>
        <name evidence="7" type="ORF">Cpir12675_004610</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000134">
        <property type="protein sequence ID" value="KAL1892287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12307">
        <property type="entry name" value="RRM_NIFK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46754">
        <property type="entry name" value="MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="152"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="110"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="317"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="363"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1892287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="380" mass="41922" checksum="474A657223170A7F" modified="2025-10-08" version="1">MAPELRKRNAASASPAVVKTTPIKNKRKAAEDSSPAVAKKPKASSKSKPKEKSTPNSKKIKASKPEPEPKPEPTADVMDIDEDETVTVADITIQDEDVEEEVDAELQALAAGLDSDNEGPSKSTFKSGEGVGKIPSIKGKKSVKSHEKEKPGVVYIGRIPHGFYETEMKQYFGQFGPILRLRMSRNKRTGASKHFAFIEFREESTASIVAKTMDNYLLFGHILKCKVVPTEKLHADVWKGANKRFKKIPYNKMEALSLKKPKTESNWTKRVERENQKRLENAKKLKAIGYSYKPIVAKNVPVPLAIENGDVPKAIEKKESVAIEETQPVAKQEPSEPAQEKEPKPTPKKGKASPNPKAKASPKTAQKPTRASTRNKKVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWS3</accession>
    <name>A0ABR3YWS3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004374</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000121">
        <property type="protein sequence ID" value="KAL1892840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="338" mass="37046" checksum="F7DB01295AE54DF6" modified="2025-10-08" version="1">MSDDHSVNFDTQGQATRPRSRRRRLSVASSANSYESLSRQEHGHIRLAYRPRQQGTTVHHSLASPSPLHSPATSSVSFSQAGSDDIPAGSESGTILAQAEALPRGVTVSRSMSRRTTRRRSSWAQSEGSNTDDGAPATEGMIEGSRWSQHWNTGTPQAPLSTRNNTRGRENVAPGESEYGYTAQRSPVAESMARVRRWGYSPSESGTGRWVAGYPMPNQTWPVNPPFEYRSRNHEPSFDIFQRQYDAAGAQFAAPPGAIGWNMGMWSQVNLDLPGNGVEVTLRHGYPGGGTYSTYSPYIGPIDATSRREHAVWMNSCVWCQICAGPICCRGIVCSRSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX89</accession>
    <name>A0ABR3YX89_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_004507</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000129">
        <property type="protein sequence ID" value="KAL1892537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1410.10">
        <property type="entry name" value="I/LWEQ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1892537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="380" mass="42725" checksum="62207FBE880ADC1A" modified="2025-10-08" version="1">MASSPSAEDDSLKKLARQRKVAVTKIQKSAAQLRCLTEDNSRLWASYPDELTPEDLQGHAKNVGLLADALKLISSRCVQLQFMAFADPITPSAVGTVINEIAINMEYLPKGVGLYCPNFYTDAFFRLLLVPSQKIANTVISIVQLVPDQGEPMSPQKKNDMLRHLSVLADLVDSLIKKLDKGPRQIIIDEHITDTHDLLVDVISELNEWKDDSLEGLEDEIASTGDQQHVLEGDLSLASDHDVQSMIDEMVNTRTKIPKNTAAHIVERVDTCTKRLRLLALFCKAIIKRRMSILPKFPANSEVIRRLQCVIEVMKALQPEADELVHSFYELEMNKVDDFMDSMIKQALLLSKTIYHDWDDKPDEFTDWLAKFQGGLQGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXX6</accession>
    <name>A0ABR3YXX6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Prefoldin subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PRF1</name>
        <name evidence="4" type="ORF">Cpir12675_004334</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the prefoldin subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000120">
        <property type="protein sequence ID" value="KAL1892925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23156">
        <property type="entry name" value="Prefoldin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016655">
        <property type="entry name" value="PFD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004127">
        <property type="entry name" value="Prefoldin_subunit_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12409">
        <property type="entry name" value="PREFOLDIN SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12409:SF0">
        <property type="entry name" value="PREFOLDIN SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02996">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016396">
        <property type="entry name" value="Prefoldin_subunit_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR016396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="198" mass="22471" checksum="9FAD317685B7C09B" modified="2025-10-08" version="1">MSSKKELAAGETNPRGIPKAPFVDRVEDYVISHDEVEGTLRNFQEMINKYQFMEMNLQKRLAGLREKIPDIQKTLETVQFLKLRGSDSEPIETTFELSETLYAKALVPATEEVYVWLGANVMLAYPVDEAETLLSGKLNAAKTSTSNFEEDLDFVREQITTMEVALARVYNWDVVQKRKIKAEKGETVEDKTKAIAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY14</accession>
    <name>A0ABR3YY14_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA mismatch repair protein S5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_004221</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000114">
        <property type="protein sequence ID" value="KAL1893243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="MutL/Mlh/PMS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00585">
        <property type="entry name" value="mutl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073:SF41">
        <property type="entry name" value="MISMATCH REPAIR PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01119">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair protein S5" evidence="4">
        <location>
            <begin position="218"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="517"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="620"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="517"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="527"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="544"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="622"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="670"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="694"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="909" mass="99709" checksum="C05E2E38A3BD76C1" modified="2025-10-08" version="1">MASIRALPQDTVRRFNSLLVITSPDILVKELIENSIDAGATVIEVLISPNTIDQIQVRDNGHGISLSNWDALGRQHYTNKLKTIDELVYKGGNTFGFRGEALASANTCGTVVVMTRTKEDDLANILLLAHGRGGVAETNSASGLVGTTVTVTQLFRNLPVRKQQFLKESPKTLVKIREIMLRLAIAKPFLKLILKVLGNNKAGWSFSPTKAPSTKDVVLQVLGKSLASSCIDIQVSDGTFAFDAFIPSREARPLGISGKGAYISVDGRPLDPLRGTAKKMDNLFKNRLCKTLGECQRPFIQANLKCPPGSYDVNVSIFKTEVIFSDEPKVLNLFQRLLDKVYGSSSYPQQKSSDSLIEKGMIPIFDKLGYVPDARYDGSLLTSHGVKQPPSQPIVIEIHDSSSSGPGSPSSDIEFLSIPDSTPPTSVIGQPPSSEIAIHSDARMVKTEKMSAQTHWEVNMVEVRDSEEVPRPLKIESIAVFVNGDTATCIQEEYRSSPSQSPRDSGLNPWTLSQQRAEIRQQKDTSNDCVSASGSDNQTQVSLDHSESRSDTLELDSHTIDLPRGNLERHGLSVGLSPPFTLTQESGLSSGGLQTCSFTPRKTNVERRFEHYTPAHFVPQKRQISSPDIARPNSNPPASFTPINQTFKPPMVGSAKIPSFNSGLGLESAHQGTGSKSKTGSTLRQSRLCFGRSDISRRTRRSEQLSQLSSQANSCGDNPPDNGLSSMSPSPPLLKPFEPHDIEISHVSDGIIVQNVSDSVMRAQGQQLARADQVGRQERDLPPDLHSIHEFSPLVHSRSTWSTPHAMDQGMQNLPLESVPINEQTQRVVLSMVMSMDRVRESYDQIGRWDMYIQRGENAFSVLDGVTTKLDLWDLEDRIRAVLELWGDVDMAGKFRGRLSLGNLKGKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYB8</accession>
    <name>A0ABR3YYB8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_004158</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000112">
        <property type="protein sequence ID" value="KAL1893376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045114">
        <property type="entry name" value="Csn12-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12732:SF8">
        <property type="entry name" value="NUCLEAR MRNA EXPORT PROTEIN THP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12732">
        <property type="entry name" value="UNCHARACTERIZED PROTEASOME COMPONENT REGION PCI-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1893376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="521" mass="57792" checksum="CE33CFF2C8473E42" modified="2025-10-08" version="1">MSLLLQFLSKILDSVHKQDGPSLGAWLKVEPTASDQYFKLAQELRSQFRDAAAVESTVAKCFPDEDPVEGRGAPWAGLVSFLREYVMYWRDVDFDDLAKTHERLCTLTNTCGVAFANPTYGGMLLETCMSLSEALSRLTLALNKRPDLMARQKGRGGGEEERKTIAEVCAEILQKIFTTCLTDRSSARNARPEGKKVGVYMFANLTLKLLFACRRKQLAQQIFTNIETNSPPLSLYPAAQRVTFLFYLGRFWLSNNSYSRASLALDEAYRQTPRVCVSQRALILSYLVPCNILIGRLPSPALLQRPEMQEIAPLYGGLSAALKVGNIPLYQALLALHRDYLMGKGVHAALAYEGRGILWRSLARRVFLLTYVPPPPGDKKPALLDLDYLEAAARFLQGRIESIPPHTLAASANTTLPNNTHLIPGLLFSANSTPGKLLPHEGVVNGSQEITTGGIELIVSSLIDMELMHGYISHSLRKFVLFRGKNMPIATAGWPTVAPAIRDRKYDEDFDMTAVPGWVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYV5</accession>
    <name>A0ABR3YYV5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NB-ARC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000113">
        <property type="protein sequence ID" value="KAL1893255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35205">
        <property type="entry name" value="NB-ARC AND TPR DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35205:SF1">
        <property type="entry name" value="ZU5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NB-ARC" evidence="1">
        <location>
            <begin position="259"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="603" mass="67338" checksum="C197FBAC2143758F" modified="2025-10-08" version="1">MTIDQCAQAYRKFSENVSTTGEHGLELYSSSGVYSARKLEDMIKQVIRESYTETKCQRQRDIGTSKNDFCSHEDVLFHDDTCTPTVVLAIAKSAEGAEPMLFKTYHLPADFSECKAWEINRATSAVAPAFTSIQLGEDEIECISSGYGRQETILRIGTGLSGAIRNPRYSIASALRGMAASSSAANIRLQKCYFHTGQYFRFDVDNGLQDFMPLDRDRTRRIPSHVKNCHDEKEYMIDEFVSTCINGTARPGHLHRRRQVLSALNDKLFAQPGFQQVVLVGFGGTGKTQVALELAHTVKNDRPEYSVFWLPGASMTVFDDAYKELVEELKIEGANDENQKTMDEGCEGEMIGNKDPKMLIKRYLESQNAGNWLLVLDDVDDFDVFGTPKEMKAPMHHFLPRSELRRILVTARTDDVAWKALDTRVDVVELDEMSPEELGAILGRSAEALHSQLSVNDLVKELNHLPLAVAQAADCISMSNMPVPDYLEVLGTTNQHKIAFLRDRHTGDTDHGRYQSAIAIAWPIAFDQIEKASQPAVRLLEFIAIIDSKAIPLSILTGLEASSSRKMQLTYCWDMASLTDGRLPTHSTCITLCTLLPDYGIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYV7</accession>
    <name>A0ABR3YYV7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">D-arabinitol 2-dehydrogenase [ribulose-forming]</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_004132</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000110">
        <property type="protein sequence ID" value="KAL1893433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF14">
        <property type="entry name" value="DEHYDROGENASE ARBD, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="270" mass="28674" checksum="F767C5FD52CBA967" modified="2025-10-08" version="1">MDSISEAPPTLSSFTLVNRAVIVTGGASGLGAVMARAIVASGGSLAIADLNITAAETVASSIRADFPTAKISIHNVDVSSKESISKCVTDVVAYHGKVDGLVTSAGFVENFPAEEYPVDRMRKLWDVNVDGTYLFATEVARWMIGAGVKGSMVFIGSMSGAIVNVPQPQTQVPYNVSKAAVRHMAASLAVEWSSKGIRVNCLSPGYMRTALTERIIQKSPELTKPWVEMTPMKRMGDPADLEGPVTFLLSNAARYITGSDLRVDGGYTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z037</accession>
    <name>A0ABR3Z037_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004098</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000109">
        <property type="protein sequence ID" value="KAL1893445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42089">
        <property type="entry name" value="YALI0F09427P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42089:SF1">
        <property type="entry name" value="YALI0F09427P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="168"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="119"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="176"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="224" mass="24479" checksum="F2CBC8BCBF1A33CF" modified="2025-10-08" version="1">MGQNYDNHINGLVLTMWPSRYLVEFNNVLSQVPLTVSPFVKLPSAPTLSYNYTKLPSVLPTSRYVAGMSAVQNSSGPNTPSYNAGNDPTSATAAGPSTIPYVGTRGGHFAHPQSIIRSCTLLREHLDRLQAEADRELEELNARIADAELAEKRRIAPGWLDSENHILVPESTTGKAADDAGKSEPMDLASEPTEEQRRKADAEADEVSAFVEMLSLKEKQKTKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z039</accession>
    <name>A0ABR3Z039_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_004019</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000105">
        <property type="protein sequence ID" value="KAL1893672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF46">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="73"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="770" mass="86537" checksum="AF87F5270357C522" modified="2025-10-08" version="1">MRSQKSLENEGPCPFATTSQSIAKASTASPGYKEKELALRPIVCKKNSDLPDSEPPRSTTKHSQSTRVRSFGGCFTCRTRKVKCDETHPICLQCERSKLICAGYEAKIRFILHHQGKSRLGTSQTEHNGGHGRRMLFTEDQRQLMSQQLTEMVHLGEIDAFLSNLESELLDNPETGVTPSLVHAGPFAIFRADGPRDSPPQGECTAQSSYIAPPALASSESSTTTSNAVISGLAADGEEDLEHIFMAESNTPPAAWLDSRQLVQQFSPSLNFCVNSISDASAVTDPASHLSPNNILELSTLSRLDTLITSNFTHTSDPSVMFQTQFLLNHYKSQMGKIFSPLRSQKPPWSILHFPRALSAFSELAVFNKINHSHAALFYAVLAVSAFNWDNLNRSYKSQSAYWRYVGGEFWLYAKRQLELSGEAEFFGDSKAKYKDILMSMLTMVTIAVITGQQDEARSFLLSAEMFISVRGISKAIKSRKIKLLHCIYLYLRIIEESTFMYPLDRQPLGNLSVPLDQMLFPSLRTNSLCVGRDVDQQCGTHFEHGLFEDPGVLGLKSGLSFFAEIYGIPGELLSYVSRITFLANEAHLVERTSPDFTVTFNRQDACQKLETEICEWEYSTEPQGAHQTGPVPTVVKLSIMPHLIIAFHSAVLIFFYRRIRKVHPLMLQHWVNQTIAKLELYEYEQHNFSIVSSGIVWPFFIAGAEAMGEPLQARFLKALYENAESTGMWNFGRAADILKALWEYRQSSNQPLFTWMDFMRERRLSLVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z140</accession>
    <name>A0ABR3Z140_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_003883</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000099">
        <property type="protein sequence ID" value="KAL1893907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013907">
        <property type="entry name" value="Sds3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21964">
        <property type="entry name" value="BREAST CANCER METASTASIS-SUPPRESSOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08598">
        <property type="entry name" value="Sds3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01401">
        <property type="entry name" value="Sds3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="201"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="314"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="478"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="337"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="499"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="528"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1893907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="558" mass="62304" checksum="99144B0C298F82EA" modified="2025-10-08" version="1">MSTNDIPMAQPLSGARRPDAAAQAKRDRKRKDLADRLDQLQKKFSQDKDLKYRDHLQRVQVDSALVTRMDPYSENALEILEEMRVEHAKTQTTNHPNESTRTLLEMAGPRFQEWAQSISDVHEYRDFQLTKQLHDYKTRIQSSKNTYNYRIETAKREQHCLAKTLRDRLINTLNAKKHRLLKEKEAFEIGDTSALMLHSNQYSFLRPSSPGGNTKRTRTRREQDDILASTNGSSHEKKRKRGADDDGSPAPVKRVLDTTDATPMWQSEKLRLSAKHTGPIYNLEKLFTEKELAMTYNTAATAAHRYMLRHRFGSGESNESVSDNDDDDAPTMERQVSHQTRSTRGANPNYSEDRYIGWEAISSFEIPANLDLAHGTEMPKMPPQQPAQYLKANLRSVDSNFPSSLGSEDINSDLQVMKLYKTFDKHHQQGASLLQTGGLRKLLEVAAQPSVQETYVAFAARPRNSNYDALRRELGITDNESAVRGSPSKNTASSNGSGNSNGSGSGSGGAAAKDAISGARRLKESLSAKGSVSMSRQSSANGVGMSRQGSSRGKGRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1G6</accession>
    <name>A0ABR3Z1G6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_003843</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000098">
        <property type="protein sequence ID" value="KAL1894059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16652">
        <property type="entry name" value="dRING_Rmd5p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013144">
        <property type="entry name" value="CRA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024964">
        <property type="entry name" value="CTLH/CRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045098">
        <property type="entry name" value="Fyv10_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037683">
        <property type="entry name" value="Rmd5_dRing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044063">
        <property type="entry name" value="ZF_RING_GID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12170:SF3">
        <property type="entry name" value="GH10162P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12170">
        <property type="entry name" value="MACROPHAGE ERYTHROBLAST ATTACHER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10607">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00757">
        <property type="entry name" value="CRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51867">
        <property type="entry name" value="ZF_RING_GID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CTLH" evidence="7">
        <location>
            <begin position="151"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="RING-Gid-type" evidence="8">
        <location>
            <begin position="341"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="RING-Gid-type" evidence="6">
        <location>
            <begin position="341"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="397" mass="44629" checksum="8548E62B2DE46663" modified="2025-10-08" version="1">MSSHNPLPTTLLLAETKKMRRAPLRSTVRDADELLALLKETREQVATSAQDGGALALTKLQNPLKNSFDSMTSSLKDVSKAQKNMGKAIDKAFPARPLPVDFPPLLHRPELVNRAIAMHLLREGQFPAASTFVQEARSFIAPMNPDQLQSYFQKMYHILTEMKKSNLEPAMEWARINHTNLEQRQSTLEFDLVRLQYMWLCKGPSVNGLPDDDNNGLIGALKYSNRIFPRFKNRNAASIEQLGAALAFSSNIEESPYHHLFDMKTAFDDVSIAFTRMFCSLLGLSAESPLYMAATAGSMSLPQVLKFSKIQSQKTEWSTTSELAFETPLPRSMIFHPIFVCPVLKEQTTAKNPPILLPCGHVICKEAFIRLKARISRLKCPYCPMEVSAEATHEIRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1K3</accession>
    <name>A0ABR3Z1K3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pre-mRNA-splicing factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_003615</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Belongs to the 40S cdc5-associated complex (or cwf complex), a spliceosome sub-complex reminiscent of a late-stage spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWF11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000089">
        <property type="protein sequence ID" value="KAL1894489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17935">
        <property type="entry name" value="EEXXQc_AQR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048966">
        <property type="entry name" value="Aquarius_b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048967">
        <property type="entry name" value="Aquarius_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032174">
        <property type="entry name" value="Aquarius_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026300">
        <property type="entry name" value="CWF11_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF5">
        <property type="entry name" value="RNA HELICASE AQUARIUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16399">
        <property type="entry name" value="Aquarius_N_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21143">
        <property type="entry name" value="Aquarius_N_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21144">
        <property type="entry name" value="Aquarius_N_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038901">
        <property type="entry name" value="AQR_cwf11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="2" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA helicase aquarius N-terminal" evidence="6">
        <location>
            <begin position="46"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="RNA helicase aquarius beta-barrel" evidence="7">
        <location>
            <begin position="508"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="domain" description="RNA helicase aquarius insertion" evidence="8">
        <location>
            <begin position="721"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="4">
        <location>
            <begin position="830"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="5">
        <location>
            <begin position="1151"/>
            <end position="1343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1421"/>
            <end position="1442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="10"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR038901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF21143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF21144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1442" mass="162400" checksum="923267613E48E0AD" modified="2025-10-08" version="1">MPKAKRLKSDTSQSLVSSEPSAGSETAMTDSVEATSSVATEANNEWLALAQNNWLGAKGSVKIKNDLLKEIWETLEKDGFRYHQLLSLEGVQTLENYLWPGFSDGSTNTHVLLIVLLLNVKRRENLDSWTLLESRLPEFSQLFRRIISMFLDNSLASDIRTHLLCFIIQAFQSLDYAPVRKECAPLVSISIWHNLSSDSFRESKLDQVPHLRKAWRASAKRFDAADDATKTRLRFERAWLYTITLDFLRRLYNESSKPEDVLYCERFIEFLCDLQSQLPTRRYVNTLIHDLQIVPVMRLSPMFCAENNSLLRDMHALLSHYTYFSIDDQTGLQHSRDYAYEKHCAVLSRLQRTALKHFESKLMVLALSNYGSIDKPRDLEPLLSELSDEELVELATLLDIRSSYPSSVGLVIDRKLIMEILLSFHERKKSFKDVAEDLALVPTEQALFESNLLRTESYDGTRPMALPKLNLQYLSVGDFLWRSLILYRCEAFYGIRSDIETALRRLMPEASKNGDVRFTSSTKMAVQISKPTILEVAPAAIGDNKPSIVKAEISFDLRRMDDRKRREWDSLRIDDVVFLLAVAPSSLSRPGAKKAEDASPADSVAAVRTAEILSVVDEKGRNLRDFNGKGRGQFGSQRKVTLKLDTHTYKADSERAEKGKGDVYAGINILLRRHSRENNFKSILETIQTLALSDVPLAPWLHEVFLGYGDPAAASYKHLPNRIHKVDFRDSFLDWSHLIESLPGKTVQPAASESSIFGPPYVLETEQPKPQIEPTAATGKSVAKKRRRDVEPAMKADIEALKVSTYQELSMGPYPSDVPKKNAIRFTPAQVEAITSGTQPGLTVIVGPPGTGKTDVITQIISNIYHNFPKQKTLLITHGNQALNQLFAKIAALNIDNRHLLRLGHGEDELEVDANFSKYGRVESFLQNRDGYLHEVSKLAACLGAPGAHGNSAETAGYFNMVYVQPVWAKFRAVCNNSETSAADIAADFPFHNFFADAPQPLFAPEAARDTVVETAEACYRHIERVFSELADILPFEILRRDKEKANYLLTNEARIVAMTSTHAAMRRQEIAALGFKYDNVVFEEAAQITEIETFIPFALQKPMTASNYGAATSTEATPQSSMLRRIVLCGDHLQNSPIIQNMAFRIYANLEQSLFSRLVRLDVPIITLDQQGRARPSIADLYRWRYQQLLDLPLVQTSREFLTANAGFRYDFQFIDVPDYKGKGEAEPTPHFVQNLGEAEYAVAIYQYMRLLGYPASKISILTTYAGQRALIRDVLQHRCARNRIFGMPRAVATVDKYQGEQNDYVIVSLTRTHRVGYLRDLRRLTVGLSRARLGLYVLGRRAVFESCVELRPAMSRFFAGGRPDKLTLVTGELWPSQRLVADEAVGVSVPGEFTSEGVEHLGLYVYEMTQTKMKELEGEDGMAAEARPEDATVLEAGNGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z238</accession>
    <name>A0ABR3Z238_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Phosphate system positive regulatory protein pho81</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PHO81</name>
        <name evidence="9" type="ORF">Cpir12675_003552</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000086">
        <property type="protein sequence ID" value="KAL1894661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14372">
        <property type="entry name" value="CUE_Cue5p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14483">
        <property type="entry name" value="SPX_PHO81_NUC-2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057506">
        <property type="entry name" value="C2_GPCPD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003892">
        <property type="entry name" value="CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041807">
        <property type="entry name" value="Cue5/Don1_CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001995">
        <property type="entry name" value="Peptidase_A2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16461">
        <property type="entry name" value="TOLL-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16461:SF5">
        <property type="entry name" value="TOLL-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25329">
        <property type="entry name" value="C2_GDE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02845">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00546">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50175">
        <property type="entry name" value="ASP_PROT_RETROV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51140">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CUE" evidence="6">
        <location>
            <begin position="97"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="7">
        <location>
            <begin position="436"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="750"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="849"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="884"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A2" evidence="5">
        <location>
            <begin position="901"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="domain" description="GP-PDE" evidence="8">
        <location>
            <begin position="1134"/>
            <end position="1434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="140"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="180"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="257"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="45"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="280"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="291"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="376"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="421"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1437" mass="158461" checksum="D736E0090705F55C" modified="2025-10-08" version="1">MSAPSEQVKSPVPESPTTVRPLDLDDDDVQDGAGDDGLKSPPPANTNSASATITTSTSNPTSSTTQKPSSPSPASTLATTPQDNTNTISKPAEQMTEAEKNENILREAFPSVEAPVIKAILTASSGNVDRAFHALLQMTDPDASKDEDESTPAPPQPPRPSGLRKYMTQLESDELYARQLAEQYENSGASYEARTHSRQAGDAHGQDLKPNELYDRDHSFIDDDLPIIKENLRKGFLETQTKVNSWITTMKKKIDEALEDENDDTSVAPSHQQKPGMGGFSRRPIGGPSRRSGDYERYDADPQVIPDDFAGMKLSADGTPLRDNGKKSPSSPNFFRPPPPQKSPVGRKVAFREEIDEIESYDSSVQRNSKDGFTGAPPATSTINTSSSAAKASKWQPLSPAVMTPVTDNDPFTLGDSDDERDTHSKKEIKMEDKEDDDAERLRKATMEAMSDSLVTESKKPKFGKQIQKRQLEVPEYATSFVNYKALKKERELEKVNAFYLQKEAELKVRLKTLLDKRKVLQSRPTSIARRSAKFTTLEEGFQQFASDLNKLQQFVEINGTAFSKILKKWDKTSKSKTKELYLSRAVEVQPFFNPTVISELSDQATTSLQELGAWRDGDQVTFEDREEHVVTTTVGTGEGDADVLLLDTVIAGNIEMLKDLVMRMKATLESGVTTEPAVVERITRAFLASIHDAPREALWVLLETGLVDIQSEDDINERNCLHQAAIYGRSEILKYGLEKGVSPARMDVYGRVPLHYASVHGRLDMLEVLLDVGPETIDLIDHDNFTPLIHAIIHDRYECVQRILQTNARLDPASDADHVPLNLACEHGLACIVELLLQHGAKIVPDAEGLYPQHLVARSAKTPKILVHLQNYGADLNQIDKLYGWTPLVHAASEGNVPCLQALLDFGADPNIVDEKDLPAVYYAAWEGHLECMKLLSTYKPHTRVSPLISQPSQLSPMSDLLGFSGSSSSIDPTPMALDLDAIPILELPPPIIPLRRYGHNFLDTKTVVQINFGESGDAPLAFFHGGKYPAARLTISSKATDLIPKNIILPFQEDTRLVSFQVDNVESFTLDFDVFPTYGAKIIGKTVALPSTFRNNSCNMNLPLFDPRLRAIGQISFTTQVIRPFGGKPLEITDFETYWKATSQLETHPSSVVTGSSLSGDYVRIYVQRTSDGVPVLWPRWTIFTGELNIPVCRLTLDQFISITSKSAARAEVSSITSLQIDSIAHIHTVLANSGIKLDEALALLPHWMHVNIQVLYPTPEEEQAFNLGPASDLNSFTDSVLNVVFDHARAQRGQSPDIVRSIVFSSYSSTLCTALNWKQPNFPVFLCNDLGRDETMAAPDVVQPSGRRAVSIKEAVRVAQSNNLMGLICSGKLLDLVPALIDAIKSNGLALVTDRSLDPINSSLRLEMIKKLPEGVDGVLRSHGVLHFNESIDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z258</accession>
    <name>A0ABR3Z258_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">25S rRNA (Uridine(2843)-N(3))-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003806</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000096">
        <property type="protein sequence ID" value="KAL1894118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021463">
        <property type="entry name" value="Methyltransf_34"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11312">
        <property type="entry name" value="Methyltransf_34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="420" mass="45389" checksum="F102543A54CA05AC" modified="2025-10-08" version="1">MAHSKGRSSRCAFQPRPKKKAPAARPPRLVKAPLPAAQLAHYQLLLRVFASTFAAELGSHNLHNAIQDVKKALFERDFAAAFTNADSLPSYAARWSPTRAACYSGLLAELEWEELMYGRPCAEKARKGDYDEDSDNSNGGSENGNGDLDPPNPTTASANPTHQQIEIVALGGGAAELAAVGSMLALNPGLTAQLTILDSGPWADVLDRLQAGLVTPPALSKYASASAHATNHELLDSPTRLAVRFEQVDVLGLAGTTRTPSVASSNDADSEETNAAPAVLRKAIYGSSTAPDRKVLVTLLFTLNELYASSRGKTTMLLLSLTELLPAGSLLLILDSPGSYSEAAVGKEMRRYPMKLLVEHTLLREERGAGNDKKWEMVESEDSAWFRLPDGLEYPIPLENMRYQKHLYRLVAPASNSLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2G1</accession>
    <name>A0ABR3Z2G1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Transcription initiation factor IIF subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_003681</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIF beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000091">
        <property type="protein sequence ID" value="KAL1894452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07980">
        <property type="entry name" value="TFIIF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003196">
        <property type="entry name" value="TFIIF_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040450">
        <property type="entry name" value="TFIIF_beta_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040504">
        <property type="entry name" value="TFIIF_beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011039">
        <property type="entry name" value="TFIIF_interaction"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10445">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10445:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02270">
        <property type="entry name" value="TFIIF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17683">
        <property type="entry name" value="TFIIF_beta_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50916">
        <property type="entry name" value="Rap30/74 interaction domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TFIIF beta subunit N-terminal" evidence="9">
        <location>
            <begin position="46"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIF beta subunit HTH" evidence="8">
        <location>
            <begin position="261"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="326"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1894452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="352" mass="40085" checksum="BD253413FFEAE54A" modified="2025-10-08" version="1">MAEVPIKNEPDAPMASGAEDDDIYEDAGDLEFYTDGNNPNANQFANMYLFRVGKALYDVWSKLDDDEEITIGHIRQWYEPLADGSPGPPRMKFRLAENIPGHQPIPKEYNLNISTGVQSTYLFSEKNLDGFKSKSSDRNPAATEGIPFSILKPKPEKVDKPKYDKRQKFVPFYRKAIPKKTKIIGQVSYDLSCAPSNPEEQKYLLAMHAHETGKTTKVEIINKRQGEVINIGTNRAANWETNLIKAPAKPAKAKGQDLKAARIPENELLDLLFRAFERYQYWSMKTLRHDTKQPEAYLRATLEKIAVLNKTGRFANLWSLRPENVRNSAKPEEMAPEFEGEEDDDMLMEDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2N8</accession>
    <name>A0ABR3Z2N8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Polarized growth protein rax2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_003692</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000091">
        <property type="protein sequence ID" value="KAL1894462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024982">
        <property type="entry name" value="Rax2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048266">
        <property type="entry name" value="Rax2-like_second"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048265">
        <property type="entry name" value="Rax2-like_third"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31778">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN RAX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31778:SF2">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN RAX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12768">
        <property type="entry name" value="Rax2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20842">
        <property type="entry name" value="Rax2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20843">
        <property type="entry name" value="Rax2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046854598" description="Polarized growth protein rax2" evidence="2">
        <location>
            <begin position="20"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1146"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="domain" description="Rax2-like C-terminal" evidence="3">
        <location>
            <begin position="80"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Rax2-like second" evidence="4">
        <location>
            <begin position="212"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="Rax2-like third" evidence="5">
        <location>
            <begin position="370"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="Rax2-like C-terminal" evidence="3">
        <location>
            <begin position="887"/>
            <end position="1140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF20843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1894462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1217" mass="128539" checksum="246D49DD9D171022" modified="2025-10-08" version="1">MTTSTSLLSLASIISLASALEFSAVTQPNIDFSLLGRVGITGDFSGISVYDYVGQNERPYSTNGSESIMAQLPNGVFTSLSTVDAVVRSMCQLSGSRSVLLGGDFTSLDGNKTHGLAIFDPSSKSITTLDGLDGRVNSLLCEDDGVVYIGGNFKTNESMNALTWSNSSGFKNLEFAGFNGPVNSIVRSSNNHIIFGGAFTGLGNASLPTELDGQAINLSTANISAESTTSNSEFSDPTSIVCRTNDSTSGGWLLEDNTAGFWKAELGYTFRPTKLRLWNANANGRGTKTWRFTALPLNGILNMTYVDSSTGLNVSCTSECPLSNNASQTYQDFHFVNTVVFNAFRIDISEWYGSGGGLNSVQLFQDDITAYAIDDFNEPTCLIPSNTVSRSSTSGTWTSVSSGQSDSEYLSTSLNGTISSSDASVTFYPDIRETGNYTVNIYTPGCIQDNTCSTRGQVNITGIMTSDGETSFSTSLYQTNNYDKYDQIYFGYVDGSRSDFRPSVTITPLDGQSVDTQTFVAQRVGFILINSTGGLNGLYDFNPNASAFDTSGFESSAINKLGSDFGIGSEVTSLDISGDTLFVSGNFSTSSVKNTVAIDVVSNNITNLNGGLDGNIAATHIEGSLLYTGGKFSSTTNSASNLSNIAVFDIESQTWSALGAGVNGPVSYVVPMDINVMNRTTERVIAFTGSFNQCIAFDNYHATEADGLAVWVPSARNWIQNLEGFPLYNGFISASVNNVSDVGSLVAGSVTSSSLGAPGAVTLTDGTLGTFAVHVLNNTGGNASNSSISKRANLENLKSSGVLAGTFFSSSNRNLSIFAGHFTAVSPNGSYVENLAMIDSENNDSMTGLGSGVDNSSVFSAVAVTDHLLLAGGRITGNVGGSDIGGLISYDLSIDEFTPNQPPPLTGTNMTLSSISVRPDSSQVFVGGSFSLAGSLPCPGVCIWDTEASQWNQPGITLKGEVSSMLWNSDNTMIVGGSLQVNETTSTSLAIYNAKSIAWDVFADSDTILPGPVSLMTAGSNDVSQIWVAGYSSSDGSIFLMKWTGEQWLSTAPTDMESGSVITSLQVFATTTKHESSETLEEKQVLVITGSINLRNFGPVSAVVFDGTGFDPYLLSLASGNNRGSISGIFVQNDSFFESNSGHMRLVFVVLIGMAISLGLILLIVAGGMLLDHIRKKREGYMPAPTAMFDRGSGLQRVPPQQLLEFLERGASTAPRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3X5</accession>
    <name>A0ABR3Z3X5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Lon protease homolog, mitochondrial</fullName>
            <ecNumber evidence="9">3.4.21.53</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 15" type="primary">PIM1</name>
        <name evidence="15" type="ORF">Cpir12675_003293</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>Hydrolysis of proteins in presence of ATP.</text>
            <dbReference type="EC" id="3.4.21.53"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homohexamer or homoheptamer. Organized in a ring with a central cavity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 10 11">Belongs to the peptidase S16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.53" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000075">
        <property type="protein sequence ID" value="KAL1895336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19500">
        <property type="entry name" value="RecA-like_Lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.5270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="entry name" value="LON domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03120">
        <property type="entry name" value="lonm_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004815">
        <property type="entry name" value="Lon_bac/euk-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054594">
        <property type="entry name" value="Lon_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027503">
        <property type="entry name" value="Lonm_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008268">
        <property type="entry name" value="Peptidase_S16_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00763">
        <property type="entry name" value="lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43718">
        <property type="entry name" value="LON PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43718:SF2">
        <property type="entry name" value="LON PROTEASE HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22667">
        <property type="entry name" value="Lon_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00830">
        <property type="entry name" value="ENDOLAPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01046">
        <property type="entry name" value="LON_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 9 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 9 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 9 10" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 10" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="14">
        <location>
            <begin position="194"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="Lon proteolytic" evidence="13">
        <location>
            <begin position="931"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="71"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="292"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="836"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1124"/>
            <end position="1147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="120"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="160"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="176"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="299"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="841"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="856"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1124"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="active site" evidence="9 10">
        <location>
            <position position="1023"/>
        </location>
    </feature>
    <feature type="active site" evidence="9 10">
        <location>
            <position position="1066"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="617"/>
            <end position="624"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1895336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1147" mass="125179" checksum="8EB0BFD3EFDC48D4" modified="2025-10-08" version="1">MLPRSTLPKQFGLARLSAPSSASASRAFSLATAHARTPHIRQALCKQSSLVRLYQRGPAFSTALSLAKEKNNKNKDADPKGFFDSSVDNVSADSEITPNPAAKKTEPTSGSASTNVSPAEAEKSSDDVADTKEAKQSSKSSSGPKDAKDARKSAASGSSSGDGSGSGSGGGKKGPRSGERSLQKPEVPEDYPQVLALPISRRPLFPGFYKAITVKDPHVAAAITESIKRGQPYIGTFMFKDEHNDEDVIRNIDDVHDVGVFAQITSAFPIHGQEGGLTAILYPHRRIKLSSLIPPGTIDPKKPSPSDKEPSPVEPEPILKSEPEEPKGDVVASFEESALSPTTATKADPKYEPTSFLRKYPVSLVNVENLTDDPYDPKSPFIRAVTNEIVNVFKEVASMNNLFRDQISTFSMSQTGNVTSDPAKLADFAAAVASGEASELQEILTSMNVEERMQKALTVLKKELMNAQLQSKISKDVENKISRRQREYWLMEQMKGIRRELGLESDGKEKLVEKFKEKADKLAMPEPVRKVFDDEIHKLAHLETAASEFNVTRNYLDWLTQIPWGIRSTENFGIDHAMSVLNEDHYGLKDVKDRILEFIAVGKLRGTVEGKILCFVGPPGVGKTSIGKSIARALNREYYRFSVGGLTDVAEIKGHRRTYVGALPGRIIQALKKCQTENPLILIDEIDKIGRGYQGDPSSALLELLDPEQNSSFLDHYMDVPVDLSKVLFVCTANMTDTIPRPLLDRMELIQLSGYVADEKMAIAQKYLAPVAKEMAGLQNVNVDLAPDAVEELIKSYCRESGVRNLKKHIEKLYRKSALKIVQEYGQDIVETPTTVTETEAEVKAKTDKKAEATDSSNVSSDSKGLNEATTASASKSTKEDESAASSTAKKPEEPRPKLIIPDSVKVVIDKNSLADYVGPPVFTSDRLYEVNPAGVSMGLAWTQMGGAAMYVESILQQPLRHSSRPHLDITGNLKNVMKESSTIAYSFSKSFMAREFPDNDFFDKANLHLHVPDGAVPKDGPSAGITMATSLLSLALDTPVAPTVAMTGELTLTGKVLRIGGLREKTVAARRAGCTTILFPRDCMHDWLELPENIKQGIDGNPVAWYQDVFDIIFPSLDREAANKSRLPPAKEGKSSKGENGEGVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z422</accession>
    <name>A0ABR3Z422_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003247</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000073">
        <property type="protein sequence ID" value="KAL1895386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40130">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40130:SF1">
        <property type="entry name" value="SPINDLE POLE BODY-ASSOCIATED PROTEIN CUT12 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140361">
        <property type="entry name" value="MIT domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="76"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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            <begin position="197"/>
            <end position="221"/>
        </location>
    </feature>
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        <location>
            <begin position="259"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="433"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="509"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="391"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="79"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="95"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="523"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="532" mass="57269" checksum="F1659569157D6EB3" modified="2025-10-08" version="1">METSPLVKAHNHARAAARATQAADTTVAINEHTLAAGEFALAANTTSSVEALRTLRLLEDHHKRLAKLLELPVRAHSAQRPTNTTIPGSTNPDGSKADGEKNGDCDGKEGVDASTKQTASANVKAAGQIPSLAQSRFPQRNIAESITNNLNSARGIRSKYSGSLVAPSISNDPASGNLETLPNKESSRSCMQTMLDTEKAASGQHQDHSAAPPAAPPAATSEDGYSRFYNAFGSIINRISSPLAFAGLPLVSEDTPTRTATPVIIEPANRRRGSSISSRSTAPAKPSRLSESSIADPDLGKIYSKATVRAMQGLPVNESFYVVPPSGHTVSYANILSYADKEKRRLTASASQYSCASVTAPSDETDADFVDAGEGLPGMPKKRTVRQGQNDNELRRAADELRRQNEGLQDVVNTLQKRLRVFEASAQSLTESRIMGPKSPNSMSNSGLRVPPPLVSPTSLLGDDALKRENKEIEQKLSEALQRLEVVERDNEKMQKKLRKYKEQWDALKESAKARRTPKIGTDNESMASRIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z584</accession>
    <name>A0ABR3Z584_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphate transporter (Pho88)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PHO88</name>
        <name evidence="2" type="ORF">Cpir12675_003232</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000073">
        <property type="protein sequence ID" value="KAL1895372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012098">
        <property type="entry name" value="SND3_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28112">
        <property type="entry name" value="SRP-INDEPENDENT TARGETING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28112:SF1">
        <property type="entry name" value="SRP-INDEPENDENT TARGETING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10032">
        <property type="entry name" value="Pho88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008756">
        <property type="entry name" value="P_tr_PHO88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="178" mass="19494" checksum="49EBBEDE4D4FDF85" modified="2025-10-08" version="1">MLGMMQVAKRVPFEDPNVLNMVRGGYILSNVIILGLYLVIQAKTQKKKDLTVLKYVEPAPMGSTEEPKLVATTIHEYDMSQLRTLMRGQVTAVAIMCVLHLYMKYTNPLLIQSILPLKTALEANLVKIHIFGQPAVGELKRPFKAAAGFAQSLQGAVQTDAKSVKAAERAGRGGAKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5N7</accession>
    <name>A0ABR3Z5N7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Bromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_003171</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000070">
        <property type="protein sequence ID" value="KAL1895586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04369">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037382">
        <property type="entry name" value="Rsc/polybromo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16062:SF19">
        <property type="entry name" value="PROTEIN POLYBROMO-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16062">
        <property type="entry name" value="SWI/SNF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="3" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Bromo" evidence="10">
        <location>
            <begin position="35"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="10">
        <location>
            <begin position="307"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="131"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="457"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="158"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="188"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="258"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="494"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1895586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="535" mass="59301" checksum="A40CE3BF4047C453" modified="2025-10-08" version="1" fragment="single">MEGLKAIADKGESPAITTEAGLKCLATIRKTADKSGRIICTIFESLPPRDSNNEDYYKKTRLPISLETIEAKLKALKYNTMTEVESDLKRMVQNVKETHYKKSQAFEDAERVRKAVSNYMVKHNPAYLDRTYSAFPTPFPPSEDEEMADASESVESTNGDEMDVDDDANEQAQTSGKSQSRKGKNEPENESDDESDAQENEDDKEDDDEEDEKRDPAPMPPITPAKRRGRPPRSASATAAGAAAATASVATGTRHSTRTPNKTSASSTPAPSNVKKSEEELLRLTSYKGLTFQEAQEKIVEELLHKEEDGYEGPYYEAFINLPPRELKDYYQVISEPLSLRKLKKHVQGFQTKKLITGVTQFRTWKAFEEKASLLWSNAYYYNEEGSEIYDIAKDLEVFFKKHLKEAKTHTIEPTPSTSATKVILKSRTPTAVPPSKIILHASRNRRDYTPESPAVIAKKAKDDHRVSSTTPVPTRERTKAKTVTSAPSSAADSDGESEDESGDDEEMEDADADADADGDADADADADANASDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6B9</accession>
    <name>A0ABR3Z6B9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP cyclohydrolase I type 2/NIF3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000066">
        <property type="protein sequence ID" value="KAL1895814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1390.30">
        <property type="entry name" value="NIF3 (NGG1p interacting factor 3)-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002678">
        <property type="entry name" value="DUF34/NIF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036069">
        <property type="entry name" value="DUF34/NIF3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13799">
        <property type="entry name" value="NGG1 INTERACTING FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13799:SF13">
        <property type="entry name" value="NIF3-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01784">
        <property type="entry name" value="DUF34_NIF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102705">
        <property type="entry name" value="NIF3 (NGG1p interacting factor 3)-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="307" mass="32352" checksum="AF74E2092161B0F2" modified="2025-10-08" version="1">MSSQWAQGPVQVTSPAFTQLVVEGMRDMFPETLADRAWDNVGLLLDNTKLASEAEHSTKPVVMLTNDLTYAAAEEAIKGDASVIISYHPIIFRGLKALTTADPQQATLLLLARHNIAVYSPHTALDAAQKGINTWLVECAVGSLISLSDIQPVKPIASLPAGITYGGYGATVTLPAPSSVASIIKSFAAGIGGPSHLNIAVPDGCDLSSAMVSGIAVCAGSGSEVLRGSKAQLWITGEMSHHDALAAVQKGHIVVTAFHSNTERQFLRQRLQPMLSNWLKTAGATDTNVLVSDADRDPYTVVDLGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6H1</accession>
    <name>A0ABR3Z6H1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PIG-P domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_003100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000068">
        <property type="protein sequence ID" value="KAL1895767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052263">
        <property type="entry name" value="GPI_Anchor_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013717">
        <property type="entry name" value="PIG-P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46346">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46346:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08510">
        <property type="entry name" value="PIG-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="PIG-P" evidence="7">
        <location>
            <begin position="169"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="97"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="125"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="137"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="324" mass="35700" checksum="30256B75E28E4F2D" modified="2025-10-08" version="1">MAMPTPSSGPATHTRNNATPNTNTPRLIRNGTRISSGSGRASMDGSTSTGGGDRSNNFTFELMAGDDESIDEDLNRSYGRQHRGFENSFDSSLSDGSDPDDDDDEDDESSHPWPHHQNDFAPPYYGRPPTPLPPSPSITSLLRPSRPTTPDASDDELEPVPRAAPRVPTYEYYGFILYLFSSLCFLTYLLWAFLPSPFLHALGITYYPDRWWALAMPTFLVVTLIYIYVALGSYNTEILTLPLTAVETVVDEAAQVALVDATGSLRDGSRMTPAKIDIMKGYGDLATIWSEGTDAVMDIPLGAVCEVLYARGPEVFDWEDEYNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6K2</accession>
    <name>A0ABR3Z6K2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">holo-[acyl-carrier-protein] synthase</fullName>
            <ecNumber evidence="1">2.7.8.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_002859</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.7" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000060">
        <property type="protein sequence ID" value="KAL1896266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="entry name" value="4'-phosphopantetheinyl transferase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055066">
        <property type="entry name" value="AASDHPPT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050559">
        <property type="entry name" value="P-Pant_transferase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12215:SF10">
        <property type="entry name" value="L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12215">
        <property type="entry name" value="PHOSPHOPANTETHEINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22624">
        <property type="entry name" value="AASDHPPT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="4'-phosphopantetheinyl transferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="4'-phosphopantetheinyl transferase N-terminal" evidence="4">
        <location>
            <begin position="42"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="4'-phosphopantetheinyl transferase" evidence="3">
        <location>
            <begin position="144"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1896266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="318" mass="34572" checksum="6621285297AA6ACA" modified="2025-10-08" version="1">MAVAANNLSSPKATVVQWAVDTRKLWPSAVQTSDLLHAAKLPLSLLTYAERQKALGFVFAKDAKLSLVSSLLKRLLISRYANVPWSEAHAQPDSHQKPVYRCTATNSEPVAFNVSHQDGLVVLAAVCGYPRATENDPLAGIVEVGVDIVSTSERRSRDLAGLAASDAWASHVDVYAEIFAPAELRYLKSLCTPPHIASASSQEADFRLRYFYALWCLREAYVKMDGQALTAPWITALEFRSFHPPVPGTGVVDGFNVCLHGVPVHDARIELRSLGEDYMVATAIRTPARPHAAAEFVLGPYLVIDLEAELRAVVGAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7P7</accession>
    <name>A0ABR3Z7P7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mitochondrial resolvase Ydc2 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002930</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000062">
        <property type="protein sequence ID" value="KAL1896222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039197">
        <property type="entry name" value="Mrs1/Cce1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015242">
        <property type="entry name" value="Ydc2_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28072">
        <property type="entry name" value="CRUCIFORM CUTTING ENDONUCLEASE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28072:SF1">
        <property type="entry name" value="CRUCIFORM CUTTING ENDONUCLEASE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09159">
        <property type="entry name" value="Ydc2-catalyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mitochondrial resolvase Ydc2 catalytic" evidence="2">
        <location>
            <begin position="239"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="513" mass="55631" checksum="AF40B9CA3C854A7F" modified="2025-10-08" version="1">MPSASSSAAVAAFQVSSALTIPRLRRLAFHVGSQMTARKAELKAGIETAVMLQAKHTASTALATSAAAGNATRGTVRTRLKPDATSKCSSLALLSPPHQYVVVSIDMGIRNFAICVLGTGVSTPQTPETAQHCKAQVTNISRPLWLSTPQVLAWRKYDLLELFKSSNKSAKALAAKSMQAVLTDSDAPLPPTAIKVTDFATADIPALAVRVVRDIILPLVTDAATCAGVVCPEGKPLASVRADRVLIEHQRHRSRGLMGVLHTTVLVNSLEVSLHTLLEGMREFAFDSEKGGVVAKKAPAPNSKHPPLLAPVPPTHLMDPRKVSEFWVRDIDTMLEEADARNPRSKRRRKRPAGADSQIHISGVVDEDHMATNEPDTELEASLPLRKAAPRARLTTQAIKRAKVNVLTNWLEAGALDLATPEAKNVAAMFLPAEPKSTKEKRKRKAKTKAKGQESELDPEPKQVKLEKVSSIAVRQRKIDDLADCLLQGLYALRIDENRRAMLTWGAEPFLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z895</accession>
    <name>A0ABR3Z895_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Signal peptidase complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_003135</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Dispensable for SPC enzymatic activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SPCS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000069">
        <property type="protein sequence ID" value="KAL1895744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009542">
        <property type="entry name" value="Spc1/SPCS1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13202">
        <property type="entry name" value="MICROSOMAL SIGNAL PEPTIDASE 12 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13202:SF0">
        <property type="entry name" value="SIGNAL PEPTIDASE COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06645">
        <property type="entry name" value="SPC12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00045204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1895744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="100" mass="11209" checksum="F18C429CCA96A6D1" modified="2025-10-08" version="1">MSEELLDDIRGALDGQIDFKGQTFAELIQNIVMSIFGIAAFIYGYINQDIRSALFIVLGGAIVTIILVVPQWPFYRRNPVTWLPAGTGIQTYQSLLEKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8F6</accession>
    <name>A0ABR3Z8F6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_002597</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000052">
        <property type="protein sequence ID" value="KAL1896948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="3">
        <location>
            <begin position="322"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="16"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="139"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="372"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="75"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="154"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="391" mass="43755" checksum="FD7E4CD750C2B824" modified="2025-10-08" version="1">MTSLFGLTSRCSLQPIQTSKPKAPRRSFFQRTDRSLNAGSGLSSDNDGLDPEEKSNLETPSQIKPLFSRSATASRSDKTPCSDIRRSARVSKTYLTKKLTPKPGELPESSLYKLTSILGPRDFEEEVATSPLAKIPSFMRQPLESSPGPVFKVSRQDRADSPESLHDIDMYDDMILHEEKIQTQPGACNDLPAGQGGSNENSAVVDDLHNDDAETAAQLFSEGAAQSSRRYNGSMIEDESENGYDSDVSFAFSTILSHRRLENDPNKFELKIVWSDNGSDAARTWVREEDIMMDAPSAYFEYWGSVGGRQTHVEDPDLWYMFNIKRERKSGRGKAYLIQWLGSREESWEPESSVKRVASELLQEYKANTQTLKRSKKGVAAKKGQESRKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8J2</accession>
    <name>A0ABR3Z8J2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000051">
        <property type="protein sequence ID" value="KAL1896980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013893">
        <property type="entry name" value="RNase_P_Rpp40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15396">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15396:SF1">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08584">
        <property type="entry name" value="Ribonuc_P_40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1896980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="357" mass="39666" checksum="0BE37FF0D798BB69" modified="2025-10-08" version="1">MFALPQSSVNQTQKCFITYGQMGHLDVAQPGLSKKPLRVFNEQSFVYQLDVLVPSNSVNALREKLEKIDLGPGAMKLIMTLENVLTGAFFVRSFKDGEVAMISQTTLDQDVVFECANGTNSRTLTIHLDKESYERSGLSGTPEPGKDNRSHKSRWVVKYDLTLPSMVPGKRGFERLLYACRNAFPKPQTWLFLKVSGQDVPIDHLASFNPVDIPVRHSLETIDCTMMDLQQVKTQLASASRTDLELVAAEVYEWASLIRLNSPRVSPGDSVDPYLSRYSVPTPLESPVQIAKFSWQGPVSSAMIIAVLMAAIEVTQRRDWVYSSISTLSKGVAGANTETAFLRIPDSGGQFLLWEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8S7</accession>
    <name>A0ABR3Z8S7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Calcium channel yvc1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">YVC1</name>
        <name evidence="5" type="ORF">Cpir12675_002706</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000055">
        <property type="protein sequence ID" value="KAL1896684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056337">
        <property type="entry name" value="LHD_YVC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052971">
        <property type="entry name" value="TRP_calcium_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056336">
        <property type="entry name" value="YVC1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35859">
        <property type="entry name" value="NONSELECTIVE CATION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35859:SF1">
        <property type="entry name" value="NONSELECTIVE CATION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23190">
        <property type="entry name" value="LHD_TRPY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23317">
        <property type="entry name" value="YVC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046501106" evidence="2">
        <location>
            <begin position="20"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="277"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="397"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="458"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="513"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="544"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="domain" description="YVC1 N-terminal linker helical" evidence="3">
        <location>
            <begin position="51"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium channel YVC1-like C-terminal transmembrane" evidence="4">
        <location>
            <begin position="270"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1896684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="636" mass="72460" checksum="B6AEDAAAB69C305C" modified="2025-10-08" version="1">MARWSLMSLLGLAQNPAEADSRQSWLRHERQTLLPRFHRADIPSAFPPLEVTKTALRLRFLIEQCIPCELKEEEVTRPHSTIITPKVIVAAKKAGGSSSEYAACVVFCLLVCKQWFSRQALLELWDADLHRLRAQACEVIAKAIIENEDDQEYLMHAVLLKRYAFLIDGEPTPAVNVIEKAVDLHALRVICSSGYQKCIGYLWKGWLVQDENDPSQFVDYALKADRRFSVHMDPDRMRAPIYQNAAQLLVSILYLVLYTMAINSINPGGDLDATEMVLYIFTVGYVVDEVVKVWKAGYQIFSFWNAFNSTLYGILIVSFVLRLIGLSHPMQPHSDHGRGDVAVDGIDNPREYYSRLSYNFLAASAPMFWTRLLLYLDSYRFFGAMLVVLKVMMKESLIFFALLTVVIIGFLQAFIGLDLADDLQADDVFFIIKAMANGVMGSPEYDGFDNFAPPFGLILYYLFTFVVMVILLNILIALYGSAYSDIYENANDEFLALFSQKTMQFVRAPDENVYIAPFNLVEIAVAAVTEWWMPKARFEQLNDIVMAIIYSPVLVVAAWYETQAAHAIRYNRLNGEEDDDIVHEWEQLRDQIDMEGEGWTKKVEEAKSNVEEEPAVQEIKKLRREVAELRALLTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8T9</accession>
    <name>A0ABR3Z8T9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002684</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000055">
        <property type="protein sequence ID" value="KAL1896662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1896662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="283" mass="30719" checksum="72943B0720718360" modified="2025-10-08" version="1">MSVPCFEAYRTRLIVHRKLSFLSSADRQRIDDMCLILDRVSAAADATGYLSDSDHDSECDYNDGETCPSDCGSLYSPMDEWCTGCSEAGALNTGPATGLSPAPPVGMQVRMNLSGPEQKLRRESRRLDKQTAGTGINDMKISANTGINELQDEPLLTVAHLMDIQRALDKAFMDCGSSIDRVALSVESWGEKMGGSQSNGPQTSLGGCGSEREPLILDDLVGGHATLPLFQKLLGRYKGVRNAAKRIGDTGEVEKVDGLMKWNLMKLQGLVARLGREEKSRES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9A4</accession>
    <name>A0ABR3Z9A4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Anaphase-promoting complex subunit 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">cut23</name>
        <name evidence="10" type="ORF">Cpir12675_002751</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000056">
        <property type="protein sequence ID" value="KAL1896655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007192">
        <property type="entry name" value="APC8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558">
        <property type="entry name" value="CELL DIVISION CYCLE 16,23,27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558:SF10">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04049">
        <property type="entry name" value="ANAPC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 7" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Cdc23" evidence="9">
        <location>
            <begin position="10"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="388"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="422"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="490"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="121"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="596"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="707"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="53"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="128"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="627"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="716"/>
            <end position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1896655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="736" mass="81464" checksum="EEFE99FE34860A78" modified="2025-10-08" version="1">MSLSYNDRVQLRAALQEAVIKCSERCLYQSAKWAAELLDSLPDPDDDPETFQADRTTFDPSPSVILSTGNKDPEEAALEAQETNKYLLAKSFFDCREYDRCAAVFLPDSLLGGIADNKKNLKSRRTKTSAASASAPASDPTNISPSNGSTSSSSQVPLPKISQRSLFLALYAKLIGGEKRKEEDTEMVMGAQDLGNVVNKNLIVIGRYLERWFSEPDAAQRSQGWLEYLYGMVLAKDSNDQKAMEYFINSVHLFPMNWGCWLELTNIVTRSELLNEITAQLPQNIMSFIFHVHTSLELYQHSSNLLNSLEQLIIIFPTSAFLLTCTALLAYHAKDFYGAEQTFSKLLALHPHRLDSLDHYSNILYVLGMRPKLAFLAHLCSNVDRFRPESCVVIGNYYSLLSMHEKAVQYFRRALTLDRSCLSAWTLMGHEYVELKNTHAAIESYRRAVDVNRRDYRAWYGLGQTYEMLEMHAYSLWYYKRACGLRPWDGKMWMAIGTCTQKMGHYQEAIKALKRALMADAYYEMGSSPGSGDNFRVRGVPRQMDPEVLLQIALMHEQLDDIPTSKAYMELCMAQEVGGAAAAQALSSDIQGLHAGAGNHSSTSMRESLSAADDTVMSDDDPTSHLPPTSTPAIPTAPPSSTDSGHVEGTGVTAATSKARMWLARHALQTGEYVTASRLANELCEDGVEVEEAKALARDARARLEAAPVQGSSHVNATNARGGNASAGGLLAGERD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAU9</accession>
    <name>A0ABR3ZAU9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Derlin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_002740</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the derlin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000056">
        <property type="protein sequence ID" value="KAL1896644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007599">
        <property type="entry name" value="DER1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11009">
        <property type="entry name" value="DER1-LIKE PROTEIN, DERLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04511">
        <property type="entry name" value="DER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="121"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="228"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1896644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="276" mass="30322" checksum="7BD6A8FC24451111" modified="2025-10-08" version="1">MAALEMFWELPPVARTITATAFGMSILVYTGILPYRWIMFTWFDMLQIPPQIWRLPTSFLLTGSGLGMLFDPFMLYRGLVELEVGNSRFPRREDVVWYLICVSLMTIAFNELGLYFGLSNVYASFLPGFLIALTYTTSQDKRGLKASLFLFTIPAQLMPYALMLMGFVQDPQSGMYMLPLQISGLLAAHMWDFITRIYPEFGGGRNLLATPGFVSLFTTSPRVLRGGFGRNAAGGGTSGEGGRTVGGSAGRSTGVSNGSGVLPDSWRTRGPGQRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAX1</accession>
    <name>A0ABR3ZAX1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Arabinogalactan endo-beta-1,4-galactanase</fullName>
            <ecNumber evidence="3 6">3.2.1.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_002163</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>The enzyme specifically hydrolyzes (1-&gt;4)-beta-D-galactosidic linkages in type I arabinogalactans.</text>
            <dbReference type="EC" id="3.2.1.89"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the glycosyl hydrolase 53 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.89" evidence="3 6"/>
    <dbReference type="EMBL" id="JAWDJO010000039">
        <property type="protein sequence ID" value="KAL1897818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011683">
        <property type="entry name" value="Glyco_hydro_53"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34983">
        <property type="entry name" value="ARABINOGALACTAN ENDO-BETA-1,4-GALACTANASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34983:SF1">
        <property type="entry name" value="ARABINOGALACTAN ENDO-BETA-1,4-GALACTANASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07745">
        <property type="entry name" value="Glyco_hydro_53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045011459" description="Arabinogalactan endo-beta-1,4-galactanase" evidence="6">
        <location>
            <begin position="20"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1897818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="352" mass="38631" checksum="5F8BB5A1ACFB63D1" modified="2025-10-08" version="1">MFFAKFVSALVCGLVPVQAALTYRGVDWSSVPVEEANGLKYKSANGAASRMEDILVDSGVNIVRQRLWVNPKDGNYNLDFNLKLAKRAQDAGMKLFLDFHYSDTWADPLNQGIPSGWPTAIDDLAWALYNYTLEVSNEFHANGIIPEIISIGNEITGGMLFPTGSMGSNPYNLARLLKSASSAIRSSNLGTAPKIAIHLDNGWKWETQKWWYNTVLKQGPLSLSDFDIIGVSYYPFYSSEATIANLKSSLNNLSSTYQKGLIIAETDWPTSCPNPKFKFPADTSSIPISVDGQTTWMKEVSAVVAGVSNGLGIFYWEPSWVNNANLGSSCEYNCMFARDGTALSSMAVFNSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB43</accession>
    <name>A0ABR3ZB43_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">acetyl-CoA C-acyltransferase</fullName>
            <ecNumber evidence="11">2.3.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">POT1</name>
        <name evidence="16" type="ORF">Cpir12675_002215</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA</text>
            <dbReference type="Rhea" id="RHEA:21564"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="2.3.1.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; fatty acid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.16" evidence="11"/>
    <dbReference type="EMBL" id="JAWDJO010000040">
        <property type="protein sequence ID" value="KAL1897789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003988">
        <property type="term" value="F:acetyl-CoA C-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050215">
        <property type="entry name" value="Thiolase-like_sf_Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853">
        <property type="entry name" value="3-KETOACYL-COA THIOLASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853:SF8">
        <property type="entry name" value="3-KETOACYL-COA THIOLASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13 16" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="14">
        <location>
            <begin position="34"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="15">
        <location>
            <begin position="298"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1897789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="419" mass="43535" checksum="F57CE439202718CF" modified="2025-10-08" version="1">MGAVERLTQISGQIVGKPTPGGVEKLLQKNPDDIVVTAACRTAITKAGKGTLKDTAAADLLAGVLDALIKRSGINPALVEDICVGTVLPPGGGATEMRAAALVAGFPDTTAVRTTNRQCSSGLQACVDVASQIKAGVIDIGVGAGVESMSSQYGPGAVTEFSELLENHKQACDCRVPMGKLSEDMAQQLGITRAKQDAFAAASYKKAQVAQETGLFKEEIAPLKVKFEEPKTDSVKEVVADRDDGIRPGVTSESLAKIRASFSKDGTIHAGNASQLSDGAAAVMLMKRSTAEKLGQPILGKYVTASIIGVAPLLMGQGPWKAIPKALGLAGISIDDVDIYEINEAFASQCLWCAEQLGIPEEKINPKGGAIAMGHPLGCTGARQVSTLLYELRRTNKRVGVTSMCVGTGMGMAAVWVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB58</accession>
    <name>A0ABR3ZB58_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_002147</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000039">
        <property type="protein sequence ID" value="KAL1897804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024882">
        <property type="entry name" value="NUP58/p45/49"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13437">
        <property type="entry name" value="NUCLEOPORIN P58/P45 NUCLEOPORIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13437:SF2">
        <property type="entry name" value="NUCLEOPORIN P58_P45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="6" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047364984" evidence="8">
        <location>
            <begin position="22"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1897804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="426" mass="44751" checksum="6BD293BC15E17F4F" modified="2025-10-08" version="1">MAVRDLLRLASYMFLRFLVRLDLVSITGNTGGLFGNATAASTTTFTPTTTAIATTTTAAAPPTTPAAATLGTTGGLFGAAATTTNKPTLNQFGSAATTTPAAQTIAPAKPMFGATPAAATTAPATSQPFSTTGNMSLATPAPAAALGGGLFGAVNNTATATPKIGAFGQTAQAQNASAQPQQQQQSVQAVRLDMNQVRGSTKFEDLSKDAQDGIIKIDNIISVIMGWKAEIDGFLPAHEEQIASLGHDVIYLERKYAMVQRAVLGDDVANIQELRSMSNQNIADAQLASKAVDNLKLPMSYHVPGLWTQPTNTSAGGPSAAAVVSEPDLISYFNRHIASLGERDRKLRGYIAEIQAHMPRVEHGLYEKLTQLQATPGMGHQVGALEQIKGVLLDLRDAIIKQAVEVAKTREALMTLEQKLLGRERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB81</accession>
    <name>A0ABR3ZB81_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">High copy suppressor of abf2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">YHM1</name>
        <name evidence="8" type="ORF">Cpir12675_002275</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000043">
        <property type="protein sequence ID" value="KAL1897547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053042">
        <property type="entry name" value="Mito_GTP/GDP_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46974">
        <property type="entry name" value="MITOCHONDRIAL GTP/GDP CARRIER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46974:SF1">
        <property type="entry name" value="MITOCHONDRIAL GTP_GDP CARRIER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="213"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="302" mass="32877" checksum="FA9349E7238A74B0" modified="2025-10-08" version="1">MSPPASGSHKESNVARLLGSGSAGIAELMMFHPVDTIAKRLMSNQSKIVSAAELNKVIFKQTADAGAGAKFISLFPGLGYAAGYKILQRIYKYGGQPIARDYLTQHYGKDFESTFGKKTGKAILHSTAGSLIGIGEIVLLPLDVLKIKRQTNPEAFRGRGVLAIVKDEGFNLYRGWGWTAARNAPGSFALFGGSAFTKEYVFALQDYNKATWFQNFIASIGGATASLIVSAPLDVIKTRIQNRNFENPESGFRILTNMARNEGFGSFFKGLFPKLLMTGPKLVFSFWLAQTLIPAFDRALAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCB4</accession>
    <name>A0ABR3ZCB4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Kinetochore-associated protein MTW1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_001951</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
            <location evidence="1">Centromere</location>
            <location evidence="1">Kinetochore</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mis12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000034">
        <property type="protein sequence ID" value="KAL1898326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008685">
        <property type="entry name" value="Centromere_Mis12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14527">
        <property type="entry name" value="PROTEIN MIS12 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14527:SF2">
        <property type="entry name" value="PROTEIN MIS12 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05859">
        <property type="entry name" value="Mis12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="9" id="KW-0137">Centromere</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="270"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="349"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="375"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1898326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="386" mass="41412" checksum="C38780F2B147C0EE" modified="2025-10-08" version="1">MADATANTEILTEHFGYPPVSLLDDIINAINILAESALMSIEQGLLRSPPAALGFRPPRKNKSKKNKAPPEDIATTSVEEAARFEIDNGTHQLETLLCSSIDRNFDIFELYVMRNILSLRPDDRAWMRLRHYDGLDFSRLDDPDAPSVVGVATLRRKVSASQRLTAKLQAEKAQNNALLTTLRGLVERAVIKPDPDAQVIANGDSTEIPTSAPTAQSVTGPLAFLQATEGLGTADATAPLQTTAAFALSQLPALRALSISLRSIAADLQPPADADADDGSGPAGGETPSRRSWRKSRVEYIEIATRKHMERARGLELGLQGEVRDGEWQGAGRKISMAEVEGLESVLALMGGPVGGSGEEEHAMQGQDKAQSEGQGEKNGEAMDIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCG5</accession>
    <name>A0ABR3ZCG5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_002364</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000045">
        <property type="protein sequence ID" value="KAL1897508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053025">
        <property type="entry name" value="Mito_ATP_Synthase-Asso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44873">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 30, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44873:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 30, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="54"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="288" mass="31634" checksum="B6F19995089878C6" modified="2025-10-08" version="1">MPLHTPSKHALPHLQAPCLPLAFPPGFASTSPLFSISHRSFFSNHKPSTSQTQTHYDVLAVPATASPTAIKKAFYALSKAYHPDLNPDNPSAKARFLRISEAYAVLSVPAKRSAYDLSIPAVHRQQQHRDRQQSRRGGSYSSSNPAGGRPPSGLSNRKSDFTGPPPSFYRAGGWSAYYDKRQAAQDASTSKPGSWQGPYWPGTGPGPGPLHLAGRMAHFDAEAHFQTHMRQQVMLDRRRAVNSAREKDFDEISSGTKIFLILVMMVGGVVMVPLLIPAVRERNEKKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCN0</accession>
    <name>A0ABR3ZCN0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Endoplasmic reticulum membrane protein C16E8.02</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002058</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000036">
        <property type="protein sequence ID" value="KAL1898109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009305">
        <property type="entry name" value="Mpo1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28026:SF9">
        <property type="entry name" value="2-HYDROXY-PALMITIC ACID DIOXYGENASE MPO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28026">
        <property type="entry name" value="DUF962 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G05310)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06127">
        <property type="entry name" value="Mpo1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="186" mass="20435" checksum="E4E4F9A02CC7D8FD" modified="2025-10-08" version="1">MPMSLEKHLVFYGTYHSHPVNLAIHMCTVPPIVFAVLCLASNSGVLIPLPSWLTPPHLDLNLGTMAALTLGTLYVLLEPVAGALLAILCIYGTSLVNAQRDAHPEVANRIALETLAVGWLLQLVGNTAFEKHIHEELSHVAQAVFVAPVFVWFKILFAVGYRRELQGRVNASVNKELVKIGKEKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD55</accession>
    <name>A0ABR3ZD55_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RutC family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_001995</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000035">
        <property type="protein sequence ID" value="KAL1898289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06154">
        <property type="entry name" value="YjgF_YER057c_UK114_like_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="entry name" value="RutC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43857">
        <property type="entry name" value="BLR7761 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43857:SF1">
        <property type="entry name" value="YJGH FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="YjgF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1898289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="136" mass="14837" checksum="C8EC613D1805CC52" modified="2025-10-08" version="1">MSRCNISKGSEFEALIGYSRAVAVGDFVFVSGTTGYDYSTGHISDNIVEQTEQTFKNIEDALASAGSSIKDVVRVRYILPDRTQFKKTWPVLQKWLGNVRPAATMIQANLMEDVMKIEIEVTAAKGTALASSSVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDH4</accession>
    <name>A0ABR3ZDH4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001962</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000034">
        <property type="protein sequence ID" value="KAL1898337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="463"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="496"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="655" mass="71062" checksum="9C2B2DE5FCA17DEB" modified="2025-10-08" version="1">MDVLVPKSSRTPSMSGALDLRDTDITDDIEYGSLFPNSFGTTTLNQRSTRFGKVVQVANENHRSLRAWGRKTFSRNKMPMLDRSESDDTEGSQMPTLSDVANVKLRPRLHRRKSFSGLFQAMATMMAKDTPGNGDTEAETSLTLDVTRTSTPVSEETMAFDKIPALISTPIEYLPKTREKSECSSTFRHCIDDAVKMITGEGLGICDKSADSTDDWSSNFLRASRAYKTPLNTPTASIFEISGQSTMGYQACDGTSSSNQLITLVLPPRDEDTQCDAYHLYFSELFAFLGACPPSFSVLGIYDASHRVYYLQPPTSFDSTLKEHAVHVNEEPLALKTLPAGLRRFLSEIPTERTSSEAGSDAQKKARTTGDTTSIPMASIGVETEPAMKKRLRSDITEILRLLVSHQEERINEINKKRNGPSEIEMLRDDVRNRLGKTVEAITELMGTLSPLPEKEALRSVEATTSTPPTSGPAASIDATLLDSSPPTPGKAGKLSETASPSSRAATTADIPPPKVSAIGASPAEEGQEVQSLAEASPCRIGMTKLSHEDGNMFIVPPSILERRCRVPCVDSEHGELDGAMQKNRGRSLSGTGPFFTGSWRHEAARADHVSPFRASRLVHGNADTDGSVVSGDSEGSLDMMAEAILIANGTLNID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDK7</accession>
    <name>A0ABR3ZDK7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_001731</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000029">
        <property type="protein sequence ID" value="KAL1898728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF10">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="138"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="36"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="262"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="262"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="281"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="758" mass="84881" checksum="DEBBA96B3A67581D" modified="2025-10-08" version="1">MDDKYLHFLTFMSGGQDVPLNFYSPDSNTDHDINLNFDAGGPASTRPPPAHSSGSSQQSSYVACSTGPVATASLASSSDGASAVVTPISSSAAFAPTPEIHTHYNGGETTVFSVVDGQNWRRRSSGADHVKHRRTRSGCYTCRTRRVKCDEGRPICERCRKGKRGCKYPDPDDKPRKGAKAAKPKGREDFRLPLIKATEYAHFLPSYHPLASQKNGYIADKGVTKLETIPDLDDPEESLITCAQPPAPSAQHELSADVAQNRTTNAGSSPDSSTETSRKFSASISPTDSTAASSAAEADGPPTRSLVSKTYSHLSSDMKDCLDWYHENISHYHYCILSDSHEFFSVTLPRLALLDETLLYALVGFSVYLRSLTNPNSGIKDFLVYFNRSISTLISHLKAREETSIVRLISVLQLATLEEYLGDWISVMGHQMAARHHILLLYNSGNFMETPIGRILLAWYSRFDCCVGIIGRFETALPNDWFINFAEVMATWIAASPPDTQLFIEEGASNLRLCSHEIAKLNYNATNNRITMEGYGAEHTRILSMITSSFNTLVGRFDDPEYLIDFSQISYDVSPYQIVDLTDPKFKLYKGPFFASNVLRAEFHSIFMMLNFQQAMLDKKGSAYLECQRHAYAICAIFEGIYRYPDAPKGALLPVQACLGLAALFFPQDSRHRSWLREMFALVETTGYIQSKSARKGMTKVFNDETIAQWWYPDEQGFTKILRRVRSYTDERNLHAQKWQEELRDMNHIFSKLTIDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE34</accession>
    <name>A0ABR3ZE34_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aspartate--tRNA ligase msd1</fullName>
            <ecNumber evidence="8">6.1.1.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MSD1</name>
        <name evidence="8" type="ORF">Cpir12675_002120</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.12" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000038">
        <property type="protein sequence ID" value="KAL1898033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.30">
        <property type="entry name" value="GAD-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00044">
        <property type="entry name" value="Asp_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004524">
        <property type="entry name" value="Asp-tRNA-ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004115">
        <property type="entry name" value="GAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00459">
        <property type="entry name" value="aspS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF5">
        <property type="entry name" value="ASPARTATE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594">
        <property type="entry name" value="ASPARTYL/LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="7">
        <location>
            <begin position="202"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1898033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="696" mass="77977" checksum="61321A63E06D7F10" modified="2025-10-08" version="1">MIPRRTALHIGSRSVALLSPKRLVLPAVTQLSVRYISATAACPEKTVGGESCQHLRTEYKSFFHLPKESDLHTLKPDTQRPVTISGFLGRRRDTPKVTFADLTIGHGMSVSLVSGKGTDCHVELKRIPAHSSVSVTGLLVSKAGANGKPGTRELQLQSIHCLNPFDKSIIVSKGVKFPPQSRHLQLRFQPEYGRRLQFRSWLKNELGRQADQLGYTDIETPILFKSTPEGAREFLVPTRTKGKAYALPQSPQQYKQVLMASGLRGYRQFARCFRDEDLRSDRQPEFTQFDMEKAFATGSDVMSDIEVMVRGVWKEMEQRFVRADMEGAMIPVFKNSDYTERTTEIQSMPDKAFPRLTYQECMHWYGVDKPDLRIPNKITRIEHLISRDFASMISDLENPAVEAWVVRFDNGEEEEVRKFVYEFLESLPAEYKNNKAGAPTAIVHSPRLPMCGFSSFGPGGLEAVETQASPESGLNSLEPGDVVLFQAREDEMFQGGSTAMGEIRSMLWNSAVEKGLIKKPDAFCFLWVTEFPLFTPSREDSAPGQGGTAGFSSTHHPFTAPLAEEDFVLLFTEPQRAKADHYDLVLNGTELGGGSRRIHVAEIQEFVMRDILKMKPEGIAEFSHLLNALKSGCPPHAGFAFGFDRLSALLTDTSSIRDVIPFPKNMKGEDMFAKSPSKITEAQLETYHLQRRRSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE68</accession>
    <name>A0ABR3ZE68_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Structural maintenance of chromosomes protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">SMC1</name>
        <name evidence="14" type="ORF">Cpir12675_001704</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SMC family. SMC1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000028">
        <property type="protein sequence ID" value="KAL1898951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03275">
        <property type="entry name" value="ABC_SMC1_euk"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028468">
        <property type="entry name" value="Smc1_ABC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937:SF12">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="Smc hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="13">
        <location>
            <begin position="541"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="192"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="336"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="443"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="688"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="849"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="1047"/>
            <end position="1081"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR005719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1898951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1251" mass="142956" checksum="FE3098993061808E" modified="2025-10-08" version="1">MGKLIRLELCNFKSYKGHHTLLFGDSYFTSIIGPNGSGKSNSMDAISFVLGIKSSHLRSAHLKDLVYRGRVLKTSKINDDGSATTEETHDAEDAESLDKSSLNDPRTAWVMAVYEDDAGEEVRWKRSITTQGSSEYRINERVVTAQQYNAALEAENILIKARNFLVFQGDVEAIAAQSPQDLTRLIEQISGSLDYKAEYERLEAEADVAAENANHQLQRRRGINSEIKQYQEQKKEAENFQRKTDERDDAIVTRTLWKLYHIQTTMDESTTKIRNHQEDLKEHRRNVESFERKLEEARKDQSSTSREIGKIERAIRLKERDMESSQTGLIPIEEKIQTINQEYANLTDRLETTRKDVKQYQDVVNRTKSDLATVEKAEELYEKEHSERMKKLGKEVTDGDRKEYQALRHQVNTKTSSIQSNLSNFVRQQKTDESTVSTFKGKIDLAKTALEKHKTELDSLNQRKFATDSVVKQLAKEIDSKKKQFNHMQSERVRTNQKRTELEEKIESLSAKFREADDGRRQNDREARMKEMVVSLKRIYPGVKGRIGSLCKPKQKKFDEAVIVALGRDFDSVVVDTEKTGISCVQYLKEHRFPPITFIPLDNIKVNAVNTAIKGINGARLTIDTIDFDYVYERAMAYACGNSVVCDSLEIARRVTLKTPVKSVTLEGYVIHKAGLMTGGRGPEKGKRRFEEHDVQNLERAILAAKEELDKLPRRERNAEEALQHELSSLQQRHALAKNELDALERNIANMTKLADNEQRKLADLEPEFADKSAALARIREKVAALQKEISVVEDRIFAKFCKRLGYSDIRDYDAQQGSMEQEIAEERSKFSAQKQRLNGNLDWENSRCDATKARVSNLEAQLQKRKKDLKGYNSEKTKIQKSLAVAEEELDALKETLEEYRSELDEKAEKVAEARQELQKRSREIDALQKEISALESVVQTQGNAKFNLLRRCKMEQINVPLASGSLDDLPNQDNILLVSDPDAMELDEEDEDEQMMDAAMQDHGIEIDFDNLDDDLKDSDDPSVEEGLEEKLTALTAELEKLNPNMRAIERLESVEGRLKSTERDFEDARIEHKQARDAFNEVKALRFELFSKAFTHIQEQISNVYRDLTRSEAYPLGGQAYLDIEEDTDTPYLSGIKYHAMPPLKRFRDMEHLSGGEKTMAALALLFAIHSYQPSPFFVLDEVDAALDNANVGKIKKYIREHAGPGMQFIVISLKAGLFQDSESLVGVYRDQDVNSSKTMTLDLRKYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEC7</accession>
    <name>A0ABR3ZEC7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">3'-5'-exoribonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">MTR3</name>
        <name evidence="10" type="ORF">Cpir12675_001671</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000027">
        <property type="protein sequence ID" value="KAL1899011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050080">
        <property type="entry name" value="RNase_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953:SF2">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT MTR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0271">Exosome</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="9">
        <location>
            <begin position="36"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1899011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="289" mass="30934" checksum="5C23926CE38388DF" modified="2025-10-08" version="1">MADRRRINGPAAATNPPVYLPAKVENSSRTRSNDGIRAAFLRTGVTPTASGSAYLEIEKQLSSLQTTKVTNGMKLICTVHGPRALPRSAPFSPHLVLATHVKYAPFATRQRRGYLRDTSERDLSVHLETALRGSIIAERWPKSGVDVIVTIIEGDDPRDSVESINNSDWDMMNILAGCITVASAAIADAGIDAVDTVSGGVAALVPGTSSQSPVIVLDPVPSEHTEILAMCCVAYMPSRDEITNLWLKGQIPPEVEGIHLQLISRAIQAAKGSRSVLSTSLMEAVKVDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEU7</accession>
    <name>A0ABR3ZEU7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002026</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000035">
        <property type="protein sequence ID" value="KAL1898318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052061">
        <property type="entry name" value="PTE-AB_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260">
        <property type="entry name" value="UPF0644 PROTEIN PB2B4.06"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260:SF1">
        <property type="entry name" value="UPF0644 PROTEIN PB2B4.06"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Thioesterase" evidence="2">
        <location>
            <begin position="182"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="283" mass="30860" checksum="C07422092CA36A88" modified="2025-10-08" version="1">MATRGIWGLRTALRPNIAGPMAKPRSIGIRWGSADASGPTKRNPKAVLLFRLLGVGFYTTFAVGFGALLTMATTVPASALGLSFYSAEEGLLRHKPADEVAREIERQMDEIELVKKLRADPDITESRPHLQMPDKVRAQNLTAKSLQGPALLATVPVTFGSKNGMEITTVMYLGRDLCGHPGIVHGGLLATILDEQSGFCCIPKMPQRMAVTAYLNINYRKPAKADGFFVVKTKIENLDGRKAFVNSTIESLPKDGSKGDVVADADSLFIQPKWANYMPRFIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEV8</accession>
    <name>A0ABR3ZEV8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidylinositol transfer protein csr1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CSR1_1</name>
        <name evidence="3" type="ORF">Cpir12675_001850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000031">
        <property type="protein sequence ID" value="KAL1898646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052432">
        <property type="entry name" value="PITP/CRAL-TRIO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46590:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL TRANSFER PROTEIN CSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46590">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL TRANSFER PROTEIN CSR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="214"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="450"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="471" mass="52787" checksum="287EA11B088794D5" modified="2025-10-08" version="1">MHIPPAADKTTSMTSTTIPPGHVGNLTPEQEEKLKKMWAALYRIFGVTSSGDDTSATTNGTLALPGSSSGTAKDGEKEKLKKKSLFSRKPKEPTDAAIAQADADDKYGQTKLFQETLQKETPDALRNSLWSMIKHDDPDSLTLRFLRARKWDVEKALIMFISAVSWRSSEMKLDTDIMVNGDAGALRDSISGTGDAKIDGMGLMDQIRMGKAFFHGCDKESRPLCFVRVRLHHQGEQSEASQERNTVLLIETARLMLQPPVETATIVFDMTGFSISNMDYAPVKFMIKCFEANYPECLGVVLVYKAPWVFQGFWKIIRGWLDPVVANKIKFVNSVKDLSAYIPEDRIPQELDGTENWSYKYVEPVDGENDLMKDTATRDKIQAERDQYYKDFEQSTIRWIKGDSDTTSQRNEVKAKLRQNYWTLDPYIRARSLYDRTGVLNPGGKVTYYPTNSDASSSATAVSETPATGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEY1</accession>
    <name>A0ABR3ZEY1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_001693</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000028">
        <property type="protein sequence ID" value="KAL1898940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039297">
        <property type="entry name" value="COX7a"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02238">
        <property type="entry name" value="COX7a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1898940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="67" mass="7578" checksum="0A1C8B5DB621AD3F" modified="2025-10-08" version="1">MAFVDAKNRVPTLQKTYQAAYKNHTRLWKISPRSGLLVAPYTAILFGTTAACMYGMSRKALGYNSWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFC4</accession>
    <name>A0ABR3ZFC4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HTH TFE/IIEalpha-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_001705</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000028">
        <property type="protein sequence ID" value="KAL1898952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039997">
        <property type="entry name" value="TFE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017919">
        <property type="entry name" value="TFIIE/TFIIEa_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002853">
        <property type="entry name" value="TFIIE_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024550">
        <property type="entry name" value="TFIIEa/SarR/Rpc3_HTH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13097:SF7">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13097">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIE, ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02002">
        <property type="entry name" value="TFIIE_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00531">
        <property type="entry name" value="TFIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51344">
        <property type="entry name" value="HTH_TFE_IIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH TFE/IIEalpha-type" evidence="4">
        <location>
            <begin position="4"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="258"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="332"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="375"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="263"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="280"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="336"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="381"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1898952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="396" mass="44365" checksum="371D5BFA86A9F800" modified="2025-10-08" version="1">MDLAQNLVRMVTRAFYETRHIIIVDAVITHSALRDNDLAYIMSMNIKDLHKLVGKLLEERLIHKFGRPELREGQTRPVTQTYYYIDYRQTLDAIKWRVYTITKDIQGNSITITEKKEYFCNTCGADYTNLEVFSSFDESSGFLCERCGSPLVHDLERNATGHEQSTRMNNQINFITERLQQIDGVFVPDNNFEHALANSRPVLRDTSNPGSTSMPVDIGISRPTAVKGLANTGPKSLEVSISASDGPTDAEIAAEKTRKEKIAQQNALPSWMSNSTVTGDSFSANANDDSSLPVIKPEEDDKTALAAQADANKDHAAIDDYFLRLKEEQERLKLQDEEEGSDEDEDDFEDVVAAVTIDAPSIAVPDLDDSRLAKKVKLEEPVSDESEDDDMEFEDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFD5</accession>
    <name>A0ABR3ZFD5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_001445</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000022">
        <property type="protein sequence ID" value="KAL1899408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1899408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="63" mass="7604" checksum="DEB20ED97F61341B" modified="2025-10-08" version="1" fragment="single">MCQYYAHQFVCKHKSLSFARYCERAGLIQTPCQDRSIWQTIGMDNACEECIMYFPDKFPRRRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFI8</accession>
    <name>A0ABR3ZFI8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">rRNA 2'-O-methyltransferase fibrillarin</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Histone-glutamine methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NOP1</name>
        <name evidence="10" type="ORF">Cpir12675_001687</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-glutaminyl-[histone H2A] + S-adenosyl-L-methionine = N(5)-methyl-L-glutaminyl-[histone H2A] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50904"/>
            <dbReference type="Rhea" id="RHEA-COMP:12837"/>
            <dbReference type="Rhea" id="RHEA-COMP:12839"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61891"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. Fibrillarin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000028">
        <property type="protein sequence ID" value="KAL1898934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00351">
        <property type="entry name" value="RNA_methyltransf_FlpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000692">
        <property type="entry name" value="Fibrillarin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020813">
        <property type="entry name" value="Fibrillarin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003276">
        <property type="entry name" value="PRK04266.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10335:SF17">
        <property type="entry name" value="FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10335">
        <property type="entry name" value="RRNA 2-O-METHYLTRANSFERASE FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01269">
        <property type="entry name" value="Fibrillarin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006540">
        <property type="entry name" value="Nop17p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00052">
        <property type="entry name" value="FIBRILLARIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01206">
        <property type="entry name" value="Fibrillarin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00566">
        <property type="entry name" value="FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="7"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1898934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="322" mass="33997" checksum="60F6A06F703E7E82" modified="2025-10-08" version="1">MAPPPGRGGGGFRGGRGGGGGFRGGRGGAGGGAGGGRGGGRGGFRGGRGGAPGGRGGGGGRGGARGGARGGAAGGGNKVVVERHRHEGVFISRGKQDDLVTRSYAPGIAVYGEKRIQTEESTKAEDGTTIVNKIEYRVWNPFRSKIAAGILAGVDNLYIAPGKKVLYLGAASGTSVSHVSDMVGAAGRVYAVEFSIRSGRELLQMSMKRNNINPLVFDARMPVKYRFYIDGMVDVIFCDVAQPNPAQIVYDNARIFLRKGGYVLLSIKASCVDSTRPQEEVYADVVARMRKFNFKPKEQVSLETYERGHALVVFQYNPDYAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFY1</accession>
    <name>A0ABR3ZFY1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001388</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000021">
        <property type="protein sequence ID" value="KAL1899618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="312" mass="34481" checksum="4A134F1313675946" modified="2025-10-08" version="1">MSSTPLIFLPAWTPRATVDLATCILENIIDGEPHWPAVSGRMTALGHCYSCAEIKDHFASTRSVLVNGYICVDDILRQAKAACRHSSRPGHTVSPSQSNLFSPSGSSAADIIWPSIERDDSEELERAVKREPLSSDCDSESDRHDKARPVSGSEYENGTDDCHHEDCDGDGDDANNDHHHGDDKELSSSLPPPKCRPIRSRFCLAYPPSSLSPPPGLSAVPSLVSSSQTRDTHDRSSVEVIYCPLRVSPVPVGPDDGRTDEQRYGVLARIMNPQRVRDSFLQVRLDARAYWARRHLALGYTPESFDQTLCMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH35</accession>
    <name>A0ABR3ZH35_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transmembrane nucleoporin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">POM33</name>
        <name evidence="7" type="ORF">Cpir12675_001123</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PER33/POM33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051645">
        <property type="entry name" value="PER33/POM33_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005344">
        <property type="entry name" value="TMEM33/Pom33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12703">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12703:SF4">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03661">
        <property type="entry name" value="TMEM33_Pom33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1900018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="288" mass="32701" checksum="F661183166736316" modified="2025-10-08" version="1">MAPPASAQKPLAERFQELAKTLQFAWFSGHVMLIFSTLLYMFQFIKFNTSGGFARFTYRVGFLSAILTYGIVVYKSFMARQKLGSRAPSGIMTIVGDENVQYMVMSVVWFLMPHFTLALLPYFVYSVFHVATYLRTNILPTIYPPTITTSPDSTPGSKVQHNPAAERYISMLRSFVNSHYDASMALVARFEIALWVELAFYALFFRRWSWVLITVYTAFVRVRYSQSMHLQTLFTSLSTQIDSKMAYQGTPPGVRQGWETAKSVTKQFYAATDINKYIGGAPAPKKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH42</accession>
    <name>A0ABR3ZH42_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000022">
        <property type="protein sequence ID" value="KAL1899385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42068">
        <property type="entry name" value="YALI0B18964P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42068:SF1">
        <property type="entry name" value="YALI0B18964P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="492"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="805"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="853"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="281"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="868"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="885"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="901"/>
            <end position="910"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="924" mass="98228" checksum="E9ADA79696BF140E" modified="2025-10-08" version="1">MPRFFTKRKQSAPEDTPAPSFRVLDRSQVNSGSSLNHPAKSATAPDSFRNLSGPGSRSSTTHSQLFNHDESDNLFAGMKIHSGSSNTTKTASTDSSSRHSGASTAPSSAAHNSDQDDAKNNRPSLSKSATSSFLGRAGRTFSFTSTKRNNEEDLTAPPVPQIPEGHLDSGRSRGLTVSTTSTALSNSTSSTATPPRVGDRNSQFDFGGDFGSMFNTFDNGNKRSSVATVTGRSLTAVRPNQPSPLNFDSISRVDAPPFSAAESRSSQDGLLASHSPRSHNVSPVASAKPKPSTPSPDREDEDTALLRDSIVASTPAEKRNVSIPRIVREHSFEAVREEADDDNMFDQTLVTSSQLAQKYVSGAPSSPRSRVMTPAQFEKYKNDRQNGNVDAPSHADNIGDDDDDVNYDDDDDDLEKAKQLAKQRKKQEAHMAVYRQQMMKVTGEAASGPRPGMMTSMSTPNLTKTGPPSPNIADDISDEDEEVPLAILAAHGFPNKSKPPARLNQMSSNPNLRQSLQPSYQRPGSSMGAGPEAPPATTGGRSGPLPAFARNLPQDPFVGAGLVRQAPRESIAMSGGAPHPAIPPVGATPGGLVGIIASEERSRALRRGGSPNIEANAARNPNFNPSGLLGHQYSNVSGGLQNSMGMNGGSMGMNGGMGMGMNGGMGMGMGMGMNSGNSLYSMGASPSVPQLNSMNQGNDQMAQMQQLMQMQMQFMHIQMQMNAQSSGMRPMSTIGSISGMPPMMNGANGMGMGMDNRASFIAHDAGGIGYMDNSMRTMSMVQPSSASWVQKGGFVPSIRMQGDYTPSIAPSERSNIGLPGRYRPVSNMPASKTTGNLRRISSMAGITNELDLQTGISTPDNMHRAASASPSKFLSPQTPTRSPQSDDDEDDDEGWEAMKAKRDKKRSLWKSKKETTPGLSALIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHK1</accession>
    <name>A0ABR3ZHK1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Splicing factor U2AF 23 kDa subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_001315</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000020">
        <property type="protein sequence ID" value="KAL1899639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12538">
        <property type="entry name" value="RRM_U2AF35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009145">
        <property type="entry name" value="U2AF_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12620">
        <property type="entry name" value="U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01848">
        <property type="entry name" value="U2AUXFACTOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="9">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="44"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="187"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1899639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="209" mass="24277" checksum="7C4E0A290B0BA065" modified="2025-10-08" version="1">MANFLASIFGTELDKVNCSFYFKIGACRHGDRCSRKHVKPTYSQTILMPNLYQNPAHDQRNRMNPSQLQNHFDAFYEDVWCELCKYGELEELVVCDNNNDHLIGNVYARFKYEDSAQKACDELNTRWYAARPIYCELSPVTDFREACCRLNSGEGCVRGGYCNFIHRKNPSPDLDRELYLATKKHLKDLGRGDRSPSRSPTPEPARRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIJ2</accession>
    <name>A0ABR3ZIJ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">60S ribosomal protein L27, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MRPL27</name>
        <name evidence="7" type="ORF">Cpir12675_001475</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL41 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000023">
        <property type="protein sequence ID" value="KAL1899359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019189">
        <property type="entry name" value="Ribosomal_mL41"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21338:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21338">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN L41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09809">
        <property type="entry name" value="MRP-L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="102" mass="11770" checksum="A355F189B6ACE793" modified="2025-10-08" version="1">MRPTSSLGIDFRKLRLTVKDINKGFYKGNRTGSMGRHTKYGGYIIEWEKVRTYAVPDLRGFKLTPFVPTAIQPELHKYAGIPDGPRSPVKYLERWKRENGVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJR8</accession>
    <name>A0ABR3ZJR8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 19">Autophagy-related protein 9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">ATG9</name>
        <name evidence="21" type="ORF">Cpir12675_000986</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)(in) = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)(out)</text>
            <dbReference type="Rhea" id="RHEA:67920"/>
            <dbReference type="ChEBI" id="CHEBI:58088"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) = a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out)</text>
            <dbReference type="Rhea" id="RHEA:38663"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine(in) = a 1,2-diacyl-sn-glycero-3-phosphocholine(out)</text>
            <dbReference type="Rhea" id="RHEA:38571"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out)</text>
            <dbReference type="Rhea" id="RHEA:38895"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Golgi apparatus membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3 19">Preautophagosomal structure membrane</location>
            <topology evidence="3 19">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 19">Belongs to the ATG9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000013">
        <property type="protein sequence ID" value="KAL1900404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007241">
        <property type="entry name" value="Autophagy-rel_prot_9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13038">
        <property type="entry name" value="APG9 AUTOPHAGY 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13038:SF10">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04109">
        <property type="entry name" value="ATG9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 19" id="KW-0072">Autophagy</keyword>
    <keyword evidence="14" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="12 19" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="13 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7 19" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="419"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="505"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="608"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="100"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="720"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="845"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="742"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="845"/>
            <end position="857"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00024479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00024615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00024621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00024631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU364027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAL1900404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="889" mass="100550" checksum="EDF7BCEB6D1BD161" modified="2025-10-08" version="1">MDSQHISFLPSDAARVNQSFYERLRNPEAEATGLQNLDNRSFVGALDEDATFDQLSLMEENRPLNRGRNMRSTERSEEYDDNNDVPESLLVEVQHVSPIKVGQSPPLNSKKGKQTVHDRPLGSIRSQTSNLPSRIAGTSSGFAPVPAIAAPRSIHHTPGSVMSNPREKALWKWANVTNLDSFMGEVYDYFDGNGIWCIMVDKALHIVETAFIAVFLTFLTQCVAYSKIPHSASLSEVIVPKCTQRWSGLWNLGIWLYTFYFIWKCVQFFTDTRRLLDIRNFYIHLLCIPEEDMQTISWQDVVARIMALRDANPSTALNLLPGPAKFIGGQSKERLDAHDIANRLMRRDNYFIAMINKDILDVSFTVPFLGRKQVLSRTLEWYLYYCIIDFVFDYRGQVHPDFLKAESRAILSEKLRQRFVFAAAINLILSPFMLAYAIIVHFFTYYNEYQRDPSKASARRYTPLAGWRLREFNELPHIFEDRLKMSYPFATRYLDQFPKKLSDRVFRTISFISGSLLAVLAIASLLDEKMFLGFEITHERTVLFYLGVLGVIWKGSRDSIQEETLVFDPEYAMTNVIEYTRYMPDSWETRLHSFEVKQEFADMYKMKLVVFLEELIGIITAPLVLWTSMPKCSNQIIDFFREFTIHVDGLGYVCSFAVFDFKKGVGQGTKTQAPADDVRGGYHTAKHGKMAASYYGFLDNYVINPKTGIPGHLPLSQRHQYHEDEGRESASGATDSMPPQRMGKDGKESTSRSRGPNPRHQAGRTPRFAFGMQDQLSPLGSLLLDPCHQPSASVFAGSRSMHRAGTRPARNAGFDCGIMEESSEGRCMEDGSSGGLGESVWQTSVGRANAQDKSTGNEPGGDDPGVLGLIRQLKQTRRNHKAGSNGTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKK4</accession>
    <name>A0ABR3ZKK4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_001063</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000015">
        <property type="protein sequence ID" value="KAL1900064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050832">
        <property type="entry name" value="Bact_Acetyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43877:SF2">
        <property type="entry name" value="AMINOALKYLPHOSPHONATE N-ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43877">
        <property type="entry name" value="AMINOALKYLPHOSPHONATE N-ACETYLTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="44"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="197" mass="21712" checksum="A026883294AB0642" modified="2025-10-08" version="1">MAPVVRLLNPDTDSSLVPYLAALHANCITSDHTIATFLPPLSHDKLLTWWKDSISAVVRNESVMFLLFDEAPLPMSGSADMSSRFPLEQFKGSNLMGVVILAMLRAETGPFRAQVDKLLVSPKFRRRGGATALMKALEQEAAKRGQTLLMLNAESGSSAETLYRQLGWTEIGQVPNHDISPDGGLRHAIFFYKQLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKK7</accession>
    <name>A0ABR3ZKK7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="125" mass="13791" checksum="AEA6B7853EE88B3B" modified="2025-10-08" version="1">MCAKKIKPGSGSKALPGAPAPTATPLSWPPFKPALPVAPLTPEPLTEFPRKVVLLRNFFPRSLCRDYVSFLRGLPLVTTPGRPKRGDAARVNDRFQVQDAAFAQRLWEETGLQEALREEGVKGLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKL7</accession>
    <name>A0ABR3ZKL7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA/RNA-binding protein Alba-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001079</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000015">
        <property type="protein sequence ID" value="KAL1900079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="267" mass="28682" checksum="33322969BC29B41B" modified="2025-10-08" version="1">MANASTCNKRKNVSSTSPCAKKPRLQPDAEENSAGAQVTKDRSSTVSAPQQPTALTNGLSTPLPMTAHEPLLSTLSAKYSVLTLSVISSSQLRTRITRALNHLSAANNGNVADQPALVFLHARPGDVGKMISITEKVKCLMVAEGKSWVQYNRLFESASKPKGKKLGKRAGLIKSNGGAEKIVAVSVGSDAQAAQEPDAQNIHDNSNDDDDDDDYFESTARRFDKAANPPEPTRLTMSLSIFLSTTPIPELRNIRHVSIQSSKDTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKY1</accession>
    <name>A0ABR3ZKY1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000839</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="246" mass="28203" checksum="0D5E7C5116C99A6C" modified="2025-10-08" version="1">MSQVSFFTRDRPPSSNVFSEYENEDTEAGEYARSRRQRQKRSTAKCFGRGDTTVSTTNRVYDHDGEGSSDDDDVTFLLQNWEKAEEELEQDAIDFTDVEEYFGQSRQLPRSNEPIAPLTYLNRIVWLEHVLTPGTTVEVSGFDSKRYVHISQIIQGHDGVVLRGVQYVHLVDMQGMLPWSAEQHRNEVCAVHHVDLDDTRDEEIQAAVEVPLKSVTDVLILKTCNALWPIHATANDELICRWKFVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLX9</accession>
    <name>A0ABR3ZLX9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021514">
        <property type="entry name" value="DUF3176"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394:SF5">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11374">
        <property type="entry name" value="DUF3176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="249"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="585"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="713"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="728"/>
            <end position="740"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="767" mass="82612" checksum="9E26FF3119C49FC9" modified="2025-10-08" version="1">MSHFQNPNHKQSSSNFRAVSHGISPIRRFELRDSIRRKPVPMSPTSSSKRRGRYRQSHDHQPSDVNNATYAEGTAGVSSTLPSTRRAKNPLEKQLITIIPDQLGQRAPKSADTMSYVPRTVIARPGRPTKRRTSIWRQIVDGWRSELLCCIVSVCCVIIILAILGTANGTPLLALPYEVPINAVIQFPITIAVFSLLLPLSSCISQWKWLWFLSAKKSNLSDFQKFDAGSRNIPGAVSLFLALKMASPAFFGALLVILAVAVAPITQFAVAYTDGLVVVATGSDIAAVKTLQVVGPGSGSLDVFTGAVNQGLKVWDQSGLDPNIPAISCPTGHCQFPQVSALSVCSSIQNITDHLVISEDTALLPSLQDDCSLEYDANRYSIVACKTPQSQTVSSAFSPRSAIIYSMPVIFSQPKIQAGANSTPPLFGALEAIFSLCANTYNVSVSNGSINAYLIESSTLQTTQDFAGVNVNCTVADGETASSPALCRIQPNLGAAVLEAETDGDGSRYVAAYSVLEELALAMNAAVSGRWSKLVTDDTEEEGINTDSDSTDAATQASLSNITTAPVATTQGTALSIQPVLTVSWAALSLLMFETAATILFLFFTMIVNAYRKSPVLKSSATAQLVALGESARQAVGGIDEAGMLDRKARVLDVVYEDRWLDDDITVDDDIFVIQEPEVIQRGRPRKTATFSEDEICVFPLSQAAYESQTITPSPAPVIQPIPDQGSRHTTASVRRQLSQWEYGDSLTAMDQQDMETIQGKGKTETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLY4</accession>
    <name>A0ABR3ZLY4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_000662</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000008">
        <property type="protein sequence ID" value="KAL1901172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20339">
        <property type="entry name" value="BRcat_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20353">
        <property type="entry name" value="Rcat_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16630">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047545">
        <property type="entry name" value="BRcat_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051628">
        <property type="entry name" value="LUBAC_E3_Ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047546">
        <property type="entry name" value="Rcat_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047544">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770:SF47">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770">
        <property type="entry name" value="UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26200">
        <property type="entry name" value="Rcat_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="273"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="588"/>
            <end position="640"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1901172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="811" mass="92837" checksum="19A1BE4972C5705A" modified="2025-10-08" version="1">MDLDQKPIERGAHGEIKDDVYMNEIPDYGDVDHDILALMAQSVSSSDPAADCAQRVTSIFPLIDTDFLEAMSVRHVYNTDAIVNSIISDMDQGKTYPRQKWLVAGAEHKPQNADGNVPLALEIPAEDASLEELELYLETLEKRVANNSEDLPYDDNYYPLARACLKERFRNLYTSFIDQKFKRNGYRLLPTYAAILDDLKINPARKKTKTPSNPKLGSLEDLKQYKVQLSQPGQILAVDEYTIVLHIESVEERIARIKEIQDAADLLDLKEGSSFECGCCFTRVALRKVVHCNSDEGQHPFCVGCVRSYAETQIGIRQCQLTCISMDGCEAIFGRTSWSKFLSPTTIVALEKIERQTALSGPGLENIFQCPHCEFMAEYPPIEEAPVFFCQNPGCSKESCRSCGRAGHGSNPCQTVAEDLKNPETARHLVEEAMSDALIRRCNKCQSPFLKEAGCNKMTCSVKTCRNTQCYVCGMDADYSHFYRAGEGKRAGPKCPLWDTEAETTKRYEKAIEEARKSTLESILDQNPFLKKDAHSLDPNAYLSAKRPGRSAVTKIYRSVRQPSLRGHPRPRPRLWAQIHRPEQVQPQEQNQQQKLEQQQQIEQQQNQQLEQQQKQQEEEEQQQLEQQLKQQQMQQLQQLMRLQLMPKQQHQQQQPPQYEPQPHLNFEFQMQPGLQEEFQYHHLHFQPEFQYQMELEPQYQLHQQANFFQPFFPQQMMPFFAPMDTQIPFDPYVPVFQPLVPSVQTFAAQNNNVLPAQLPLPHMDLGPMNYGALGLGRMVPGQQLQDHTAYNMAHKFAGSRTNPIEIEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMP5</accession>
    <name>A0ABR3ZMP5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aminotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_000406</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005685">
        <property type="entry name" value="PRK07483.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43094">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43094:SF1">
        <property type="entry name" value="AMINOTRANSFERASE CLASS-III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="462" mass="49713" checksum="025F114BEFEA3043" modified="2025-10-08" version="1">MTPVTPTISIEPALMHRSLHELPLLITSAAGSTLYPAGPGSHPILDFCGGAAVTMLGHSHPEIIAAIAAQLQNVSYIHTAAYTSASAEALAHAVLAHDDSGSMARVYFAGSGSEATDAALKLARQFWVEKGQPGRTRFVARRQGYHGNTLGAMSVSMNKARRAPYEDVLMPNVSFVSPAYAFQYMRETGCTTEEEYSQWLADELEAEFLRLGPENVVCFIAETMVGATSGCVTAPCGYWPKIRKVCTKYDVLLVLDEVMCGAGRTGSFFAFKEEGIVPDIVTIGKGLGAGYIPLSAVLANKRIVEALRAGSAAFNHGHTFQAHALACASALKVQEIVQRDELLQRCVQMGELLCQKVFEAMASCKYVGEIRGRGLFWGIEFVNDKDTRKPFESHVNFGPRVQVAALEKGVAIYPGHGTVDGVLGDHVLLAPAFTISEEEIATAVTVLKEAYHVVEAEVDTTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMQ5</accession>
    <name>A0ABR3ZMQ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase II subunit A C-terminal domain phosphatase</fullName>
            <ecNumber evidence="6">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">fcp1</name>
        <name evidence="10" type="ORF">Cpir12675_000798</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This promotes the activity of RNA polymerase II.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17729">
        <property type="entry name" value="BRCT_CTDP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039189">
        <property type="entry name" value="Fcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011947">
        <property type="entry name" value="FCP1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02250">
        <property type="entry name" value="FCP1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081">
        <property type="entry name" value="RNA POLYMERASE II CTD PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081:SF36">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="9">
        <location>
            <begin position="157"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="8">
        <location>
            <begin position="516"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="341"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="389"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="619"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="696"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="341"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="389"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="412"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="619"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="646"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="696"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="724"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="773"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="805"/>
            <end position="815"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1900784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="870" mass="95705" checksum="3F96FA0DD52B5EB2" modified="2025-10-08" version="1">MTKTVPLGHRLRYPITVRKLLRRAGDEIKKRQVLFQYTYTTTKESGDIVRDAVITKHTAYAEWESPVDGHLKHWRIREGAVLSRDQPAFEIDEQCGHEVQFGGLCAICGKDLTEMDFSQERADTERATISMIHDQNSLKVSADLAQQEEKRMQERLLQQRKLVLVVDLDQTIIHACIDPTVGEWYNDASNPNHESLRDIGCFQLDDATSSKNLSGCWYYIKKRPGLDGFLQRMSQLFEMHVYTMGTRPYAISVANVVDPDKKLFSNRVISRDEAGSVQKELQRLFPHSTDMVVIIDDRSDVWPNDRENLIRVVPFDFFKGIGDINSSFLPARTDILPGASRADASSSLASFPTASSSPTTATMPTAAAEQEKELTKQIQDRPLAHMQEDLEKEESKHDAIPDATQPNMDLDTTTNSTNTTTPETKVDLGAAAVAAVAAVAAAPTDSVDSMAAPHSEARQHVLRDDDTELVYIERHLTAVHEKFYKAYDGQVLRNSAFGDKSSLDSVPDVGQLLKTEKSQVLRGTSIVLSGLVHMNVNVHQTELGMQLQSFGALVHTKISDKVTHLVINPARTRTQKLRQACRIPRIQIVSPDWLTACFSRWEHVDEYPYLIDVNPADRASQNDVDVPAATSTEGDIAMVDPSAPEGDAEEENDVSAASSEDEAEGGEAGSAVEEEEKQALDDLKGFDWGAADDELEDFLNSDDDEDDENGEGNAQEDGEDHDNDDTRMNERTKTCDGNRTSESIAPPLSPLSLKRKVAEEDAENGSSSHGAWPDDAAPSDASQLPSTPAVEHPMFKRLRLGAPRKSSTLRNVTSSDGRHLGVTNEGDSPASGRSGSVDPAASITTQDLEDDLDAALAAELEAGLADEMGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMY1</accession>
    <name>A0ABR3ZMY1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mediator of RNA polymerase II transcription subunit 31</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">soh1_1</name>
        <name evidence="9" type="ORF">Cpir12675_000564</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the Mediator complex subunit 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1340">
        <property type="entry name" value="Mediator of RNA polymerase II, submodule Med31 (Soh1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038089">
        <property type="entry name" value="Med31_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008831">
        <property type="entry name" value="Mediator_Med31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13186">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05669">
        <property type="entry name" value="Med31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0010">Activator</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="120" mass="14086" checksum="E5693A652A4B50FA" modified="2025-10-08" version="1">MAEKLESPSQAPPEIEQTYGGYSRFEIELEFVQSLANPMYLNHLASQKFLQQPAFIEYLGYLQYWSKPPYLKYLTYPGPTLRNLELLQHERFRTEILGPELVQRMIDEGMSAAVEWHKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP57</accession>
    <name>A0ABR3ZP57_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Casein kinase II subunit beta</fullName>
            <shortName evidence="3">CK II beta</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CKB1</name>
        <name evidence="5" type="ORF">Cpir12675_000122</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 3">Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the casein kinase 2 subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1820.10">
        <property type="entry name" value="protein kinase ck2 holoenzyme, chain C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016149">
        <property type="entry name" value="Casein_kin_II_reg-sub_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035991">
        <property type="entry name" value="Casein_kinase_II_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000704">
        <property type="entry name" value="Casein_kinase_II_reg-sub"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11740">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11740:SF0">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01214">
        <property type="entry name" value="CK_II_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00472">
        <property type="entry name" value="CASNKINASEII"/>
    </dbReference>
    <dbReference type="SMART" id="SM01085">
        <property type="entry name" value="CK_II_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57798">
        <property type="entry name" value="Casein kinase II beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01101">
        <property type="entry name" value="CK2_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="59"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="288"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00045899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1902017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="321" mass="36116" checksum="059D5F590F636D5C" modified="2025-10-08" version="1">MSSSSGTPESWIASFCSLIGHEYYAEVSEDFIEDDFNLTGLQSQVDMYKEALEMILDVEPEDDEEEEEEEEDDEEPSLEAQEMRPTQKTERRLQKELTSDLSIIESSAELLYGLIHQRYICSRPGMQQMSEKYELGHFGTCPRTNCENARTLPVGLSDIPGKDTVKLFCPSCLDVYVPPNSRFQTVDGAFFGRTFGALFLLTFPEYDLTKRGAGVIAGVRAGGGEIPNVINGFYAKNIAPGLGSSHIYEPRIYGFRVSEYSKTGPRMRWLRERPTDMNELNETTLATVDKQKSGNPQPRRTVRARANNSSPMRVETADNDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPT3</accession>
    <name>A0ABR3ZPT3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">DASH complex subunit DAD3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Outer kinetochore protein DAD3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Cpir12675_000062</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DASH complex DAD3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013965">
        <property type="entry name" value="DASH_Dad3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28017">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DAD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28017:SF1">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DAD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08656">
        <property type="entry name" value="DASH_Dad3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="15" id="KW-0137">Centromere</keyword>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="8" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0498">Mitosis</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00044179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1902162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="97" mass="11115" checksum="8E068BCDB8D2FF02" modified="2025-10-08" version="1">MDAPTNPMGSVPELTPLEQELSTILEDLAANPSIAILDGLRDLERKTSLVFTALKSSVYNIVLQQEMQQQEMQQRQDEMEHNMEMDTEMEWDEGTMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQA0</accession>
    <name>A0ABR3ZQA0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="142" mass="15427" checksum="0F90846E2599F71C" modified="2025-10-08" version="1">MEVWQPPLQPKSQGMLEKRLEIPLSLPEAVAQTQPTPKSFYFKPPSRDTPTTSSKPRTPSKARSKAAAKAKTPSKASKEAKELKANYLPSKLATPKNRGSRSNGMQSAETSLGMSLDESKPSDALTTPPKGVKQIRLKKQVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQT4</accession>
    <name>A0ABR3ZQT4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Ndufs1 NADH-ubiquinone oxidoreductase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">NdufS1</name>
        <name evidence="15" type="ORF">Cpir12675_000073</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the complex I 75 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02773">
        <property type="entry name" value="MopB_Res-Cmplx1_Nad11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000283">
        <property type="entry name" value="NADH_UbQ_OxRdtase_75kDa_su_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054351">
        <property type="entry name" value="NADH_UbQ_OxRdtase_ferredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010228">
        <property type="entry name" value="NADH_UbQ_OxRdtase_Gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019574">
        <property type="entry name" value="NADH_UbQ_OxRdtase_Gsu_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015405">
        <property type="entry name" value="NDUFS1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050123">
        <property type="entry name" value="Prok_molybdopt-oxidoreductase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01973">
        <property type="entry name" value="NuoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43105:SF13">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43105">
        <property type="entry name" value="RESPIRATORY NITRATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13510">
        <property type="entry name" value="Fer2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22151">
        <property type="entry name" value="Fer4_NDSU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22117">
        <property type="entry name" value="Fer4_Nqo3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10588">
        <property type="entry name" value="NADH-G_4Fe-4S_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09326">
        <property type="entry name" value="NADH_dhqG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00929">
        <property type="entry name" value="NADH-G_4Fe-4S_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53706">
        <property type="entry name" value="Formate dehydrogenase/DMSO reductase, domains 1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51839">
        <property type="entry name" value="4FE4S_HC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00641">
        <property type="entry name" value="COMPLEX1_75K_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00642">
        <property type="entry name" value="COMPLEX1_75K_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00643">
        <property type="entry name" value="COMPLEX1_75K_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="12">
        <location>
            <begin position="34"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S His(Cys)3-ligated-type" evidence="14">
        <location>
            <begin position="112"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="13">
        <location>
            <begin position="251"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="725"/>
            <end position="744"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1902173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="744" mass="80746" checksum="BE8261A96C98B58A" modified="2025-10-08" version="1">MLRQTLARSALRTSGLTATRSASRAFSGTAQRPQEVELTIDGKKVSIEAGSSLIQACEKAGATVPRYCYHEKLAIAGNCRMCLVEVERAPKPIASCAWPVAPGMVVKTNSPLTHKAREGIMEFLLANHPLDCPICDQGGECDLQDQSMRYGGDRGRFHETAGKRAVEDKNIGPLIKTSMNRCIHCTRCVRFANDIAGAPEMGSFGRGNDIQIGTYLEKTLDSEMSGNVIDLCPVGALTSKPYAFKARPWELKHTESIDVHDGLGCNVRIDTRGLEVMRVLPRLNEDINEEWIDDKTRFACDGLRTQRLTMPLLRRGGKFEPADWAQALTEISVAYQQLAPKGNEFKAIAGALTEVESLVAMKDLANKLGSENLALDVEAGRKPVAHGVDVRSNYSFNSTIAGIDEADVILIVGSNPRHEAAVLNARIRKQWLRSDLEIGVVGESWNSTFGFDHLGADHAALKKALSGSFGKKLAQAKRPMIIVGSGVTDHADSKAFYETIGQFTEKHASVFNTPEWNGYNVLQREASRAGAYEVGFVPPSAEVAQTKPKFVWLLGADEFADTEIPKDAFVVYQGHHGDRGAQIADVVLPGAAYTEKSGTYVNTEGRVQMTRAAVSLPGGSRTDWKIIRAASEFLGSPLPYDDLAALRERMAEISPALVSYDVVEPTSVSDLGKVQLVDGNRGASASGEPLTKVIENFYFTDVISRSSPTMARCSAAKDTGNNKTNFMAPGMDEDKPDGQIAYGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YAM1</accession>
    <name>A0ABR3YAM1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000510">
        <property type="protein sequence ID" value="KAL1885339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046540131" evidence="1">
        <location>
            <begin position="25"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1885339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="77" mass="8711" checksum="9580E0651B9A4121" modified="2025-10-08" version="1" fragment="single">NKQLTKMHPWSIALIFAFTGNAIASAIRNDVESVKTDSNLVARFENCWWDDGTCWCEDFGMGPSIYDDEHCMGIAKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YDJ9</accession>
    <name>A0ABR3YDJ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein RTA1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_006870</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000399">
        <property type="protein sequence ID" value="KAL1886070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF35">
        <property type="entry name" value="RTA1 DOMAIN PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1886070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="289" mass="32295" checksum="28F9344F159C7A9E" modified="2025-10-08" version="1">MAGGDSNSLYKYDPSFAAAVFFTIGFLLSSIAHAFQIVKNKSWFFIPFLMGSIFEVIGYACRGIGSKETPDWSMGPFMIQSLLLLLGPTFYAATIYMILGRLIALLEAQQYSLVRPSWLTKFFLVGDIASILLQGIGGGKLANADTASQKSSGENLIVGGLVIQIMFFTLFMVVTCIFHMRIRKNPTSAIKRLDNTWHRLLIVLYVASLLILVRSLFRMIEYIQGSESVLQTEEIFIYVLDASLMLIVSVLLNIFHPSQCFSDRKIGGSGRESATQLKDYNTEYQRVNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG38</accession>
    <name>A0ABR3YG38_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Anaphase-promoting complex subunit 5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Cyclosome subunit 5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">apc5</name>
        <name evidence="11" type="ORF">Cpir12675_006837</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the APC5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000389">
        <property type="protein sequence ID" value="KAL1886935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037679">
        <property type="entry name" value="Apc5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026000">
        <property type="entry name" value="Apc5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12830">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12830:SF9">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12862">
        <property type="entry name" value="ANAPC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0498">Mitosis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Anaphase-promoting complex subunit 5" evidence="10">
        <location>
            <begin position="323"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="140"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="141"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00045696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1886935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="840" mass="94053" checksum="F3DFE9F2A3F4F2FF" modified="2025-10-08" version="1">MRYLTPAKIGLLVLIDMYVNDEVPNESHRTILDFLTLHIMGIDLHQLQHKVSPKRFYSEFGRIRFVDATVDLLASMSAFQTLLSPLPSKLEEHCLWNVFICKMWSIDSLNEINVFVLTCSRRLMTKFTDTLLSELTSDGEGVYEDEEQGEDEEEEEKEEKGEDGEDENKKVPRLDTPRKKFLITQCSPIGVFIRQCRSEILKYNFAKTARLWKSFICYRQPTLSYMRTLHPNIGKYSFDDILSSESETWSPEDISTLAGVAYGDMLATGEAADGIPISMYDLERLVARVRQAMVETRGKVSLEVRHQLEDLLGDAKVLPKGIHHLRYIEASQSRDYTSAFDQLHRFCDYSPSNKDRQAYQCSLMTLAQTNSDFGCFSEAATAMSEAISTARENGDTQTLIHCLNWMYNFSITHPALLREMEDETVLVDHRETLSYLKLKSAEVGLPPSMAGAYFLEANLGLQTGTSMASIAESATRASHLVGSNGLAFMLGLNAGTKARIWVRMGVASLALMEQEVFIKSGIVFADLVILADCMAYLAATYSVIGRCKDALSILADFQSHFGPNLVPIMTEKILKSRGVIRFRQDLNRGDFDGAQEILRQLLQNSDGIPYESSFNSLLQLEYLYHSNQLPQALELIEEMAKILDGSKYEASTHVRLLIMKARIFNKCQTPLRGFSIATRAAKLAMESLSVENICEAMEVLANLLNSLGNFGAALELLNATLPRALETASVAIMGETYLCLADTYMGMAGELGRNIQAGPFAQTPPSNLAVKQANARKVNMEKAAKSLDRAFEQFQAMDYHEGQCNVLAKKATIFRILGESDLAEKAAGQFLDIRNRQKIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG39</accession>
    <name>A0ABR3YG39_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Actin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ACT1</name>
        <name evidence="4" type="ORF">Cpir12675_006605</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000333">
        <property type="protein sequence ID" value="KAL1887289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10224">
        <property type="entry name" value="ASKHA_NBD_actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00406">
        <property type="entry name" value="ACTINS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="372" mass="41259" checksum="3F876A9430E2A8FC" modified="2025-10-08" version="1" fragment="single">EVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHHGIMIGMGQKDSYVGDEAQSKRGILTLRYPIEHGVVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPINPKSNREKMTQIVFETFNAPAFYVSIQAVLSLYASGRTTGIVLDSGDGVTHVVPIYEGFALPQAIARVDMAGRDLTDYLMKILAERGYSFSTTAEREIVRDIKEKLCYVALDFDQEIQTAAHSSTLEKSYELPDGQVITIGNERFRAPEALFQPSVLGLESGGIHVTTWQSIMKCDVDVRKDLYGNIVMSGGTTMYPGLSDRMQKEISSLAPSSMKVKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG51</accession>
    <name>A0ABR3YG51_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TauD/TfdA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_006599</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000332">
        <property type="protein sequence ID" value="KAL1887296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050411">
        <property type="entry name" value="AlphaKG_dependent_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696">
        <property type="entry name" value="GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696:SF56">
        <property type="entry name" value="TAUD_TFDA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0045">Antibiotic biosynthesis</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="3">
        <location>
            <begin position="107"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="345" mass="38809" checksum="82FCC4D3B20E3B78" modified="2025-10-08" version="1">MSPSAVAPTIPTVNVLPTKNSEAPRDIFSDGIRTSGQHNPIYEILRPYSDFPREISGPTIWTNQDYENNTERWIHRLTASEIEELGATSDEFIASGTPLTGISKASEPLGKVLAALRTDLLNGKGFILFKGFPSDAWGLHKSAVAYLGLGTYIGYFVSQNSRGHILGHVKDVGDDPTQIDKVRIYRTTARQFFHADDGDIVGLLCMQKAQEGGDSHIVSIHNVWNTLQREHPDVAELLTQPIWYFDRKGEVSHGQQEWTRQPVFYIENSGKERVYIKWDPYYVRSLARFSDRGIIPPLSSEQIRAMSILEETCQRLALHMVLDVGDIQFLSNTHLLHARTAYRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGG0</accession>
    <name>A0ABR3YGG0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Nonsense-mediated mRNA decay protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NMD5</name>
        <name evidence="10" type="ORF">Cpir12675_006557</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000322">
        <property type="protein sequence ID" value="KAL1887409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013713">
        <property type="entry name" value="XPO2_central"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997:SF18">
        <property type="entry name" value="D-IMPORTIN 7_RANBP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997">
        <property type="entry name" value="IMPORTIN-7, 8, 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08506">
        <property type="entry name" value="Cse1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="9">
        <location>
            <begin position="24"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1887409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1052" mass="119505" checksum="A0904E9E0571B68E" modified="2025-10-08" version="1">MDAGQIRSLLEAILAPNADTRKQAETQLQQFHEQPGFLNILLDILQAEQIDSVRLSTAIYIKNRVNHAWGAGVFESGGETEFLIPDAEKAVFRERILPIMATAQGLVRPQMISILQRVLHYDFPEKWPSFLDFAIQLLNTNDTRSVLTGLECLLAICRTYRYKTSDSESRHHLDKIIEGTFSRLLAICAELVDQESDEASEMLHLALKCYKHATWLELSDFLRSQAQSHGWCSVFLRTIGKTLPASAMEGEVYEREKHHWWKAKKWAYFNLNRLFIRHGNTSTVSKSSDPSQQQFAQDFTTNVAPEILKAYLAEIEKWVAKTSWLSRPCLSYTLVFLDESVRPKEMWAHLKPHLQNIITHFVFPVICLSEEDIEKFEDEPEEYLHRALNYFEETTAPDVAATNFLSSLTKHRRKQTFEILKFINNVVNEYEQAAPEVKNHVAKEGALRMIGTLAPILLGKKSPIANEVEYFIVRYVFPDFKSPQGYLRSRACDTVEKFEALDFKEERNLITVYHNILECMTDPALPVRVTAALALQPLIRHDVIRINMQQNIPTIMQQLLKLANEADVDALANVMEDFVEVFATELTPFAVALSEQLRDTYLRIIRELLEKNDKIVSDDEYLEFSDDKSITALGVLQTIGTLILTLESTPDVLLHIESILMPIIQITLENKLYDLYNEVFEIIDSCTFAAKAISPTMWKAFELMHTSFKGGAELYLEDMLPALDNYVQYGAVFLATKPEYIQALFSMVNDLFIDPKITGVDRICACKLAESMMLCLGGSIDECVSGFLAMAMGVLADNSNGNASRPRTYQVHLMEMVIGAIKYNPLLALHILEQGNWTNTFFTMWFTQMAWFTRVHDKKLCIAAIMALLSIGPQNVPASVSTGWPRLLQGVTELFRTLPQAEKNRAEALKDDLNFDSANYDYGDSEEWADNDTNWNLDEEAEEVEEEHDTTGAYFEYLAEEARKYSVDDYEDDDEDLGEESAILESPLDKIEPYQLFAVTINKLQTEQPEFYSGLVGQIPAEDQGEIQNIVNRAQHIAMEAAAIGCGAVAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGI4</accession>
    <name>A0ABR3YGI4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DNA replication licensing factor MCM7</fullName>
            <ecNumber evidence="11">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">mcm7</name>
        <name evidence="11" type="synonym">MCM7</name>
        <name evidence="13" type="ORF">Cpir12675_006544</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 16">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="11"/>
    <dbReference type="EMBL" id="JAWDJO010000319">
        <property type="protein sequence ID" value="KAL1887439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17758">
        <property type="entry name" value="MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008050">
        <property type="entry name" value="MCM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF26">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24901">
        <property type="entry name" value="WHD_MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01663">
        <property type="entry name" value="MCMPROTEIN7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 11" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 11 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="12">
        <location>
            <begin position="394"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1887439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="819" mass="91344" checksum="D43BDA7ADB5FA214" modified="2025-10-08" version="1">MLRTYRAPVDYESHQKIFQDFFQTFKSSPPPKDGVDEVSVQIDGITITENDLDDDIDDSPNAAARNAQNTAKQAESTSRYIYAEALQQLAKRKIQTVEIGLDDIYQWESSGNGDPHSSLVQSIENNTKHYVEIASRAIDSAMPELDLDVDDKDDVLDVLMARRVDRNRQLTNAGAENPDELNNMFPAELTRRYTLVFKPRSTQMKKKALAVREIRGEHLGRLITLRAIATRVSDVKPIVQVNAYACERCGCEVFQPVTDKNFSPLVTCPSEECKSTQSVGQLFWSVRASKFMAFQEVKVQELSDQVPIGQIPRSLTVLCYGSLVRQINPGDMIDLAGIFLPTPYTGFRAMRAGLLTDTYVEAHHVVQHKKAYSDMLIDYSLTARIEQYRMSGQAYELLARSIAPEIYGHVDVKKALLLLLIGGVTKETGDGMKIRGDINMCLMGDPGVAKSQLLKYISKVAPRGVYTSGRGTSGVGLTAAVMRDPVTDEMILEGGALVLADNGICCIDEFDKMDENDRTAIHEVMEQQTISISKAGISTSLNARTSILAAANPLYGRYNPRLSPVENINLPAALLSRFDIMFLLLDTPSRETDGDLAKHVTFVHMNNRHPDLDGNSIVFSPHEVRSYIAAARRYRPVLTQSASDYMVKTYVKMREGQRRAEKRGELFAHTTPRTLLGIVRLAQALARLRFSTQVTNDDVDEAIRLIEASKASLATTDHRGGRSLNASSKIYNIVKALSDSGACRPDFGPDEEEDEEEAGREMSLRKVKERVIAKGFTEDQWMRALAEYSELDVWQTTGNGSRLVFIHARDIDEDDTDME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHA9</accession>
    <name>A0ABR3YHA9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="2">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_006521</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000314">
        <property type="protein sequence ID" value="KAL1887504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00275">
        <property type="entry name" value="C2_PLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08598">
        <property type="entry name" value="PI-PLC1c_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056584">
        <property type="entry name" value="EF-hand_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF82">
        <property type="entry name" value="PHOSPHOINOSITIDE PHOSPHOLIPASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23617">
        <property type="entry name" value="EF-hand_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00387">
        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="PI-PLC Y-box" evidence="5">
        <location>
            <begin position="359"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="4">
        <location>
            <begin position="468"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="157"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="170"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="638" mass="71492" checksum="464EC1F4633663B3" modified="2025-10-08" version="1">MSTLHDPRLQAGGGHSEKERSVSYLNESNLAYLKNIFNYYGKEKDWDQEAIANFVQNVQHDGSRDQYQDSRFWEGKETLDLKSFMEYMTSSNSAATSTRKTDDYSWPLASYFISSSHNTYLTGNQLSSDSSADAYRNVLLRGCRCVEVDVWDGEDTDDLSSISSSDDDDERKHKLKVEEHRRATKKGKKGGFMSKLKRVTSMKETTSKLEETTLEDKIAAPIPDLPAPLPEPRVLHGYTLTKEIYFRDVCEAIAETAFVTSDLPVIVSLEVHCSALQQKAMVDIMKTTWGDMLLLPPGDEPTCLPTPVSLKRKLVVKVKYAPPVVEGVAEIPEELSPEELEASTASGKQIKPSKIIQELSQLGFNCRGISFKSLEQEEAVMPTHIFSLSEKAISEHYQKNGKALIEHNANFLMRTYPHGLRIRSGNLEPASCWRKGAQVVALNWQNLDEGMMLNEAMYAGTEGYVLKPPGYRSKGIDFPLESATRYTYGLAIEVYGAQNIPLPPGDKSDRGFKPYVKIELHAETPNERLNTGMAEAGDDQSYEAEYKARSKTKKGSNSDFEGESLEFSNISGVIEELTFVRFTIRDDEIGSDDLAAWACIRLDRLREGWRFVHLLDTDGMLTKGALLVKITKNKVLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHU1</accession>
    <name>A0ABR3YHU1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rho-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_006547</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000319">
        <property type="protein sequence ID" value="KAL1887442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00159">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050729">
        <property type="entry name" value="Rho-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176:SF125">
        <property type="entry name" value="GTPASE ACTIVATOR (BEM2), PUTATIVE (AFU_ORTHOLOGUE AFUA_7G04450)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176">
        <property type="entry name" value="RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="3">
        <location>
            <begin position="295"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="497"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="577"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="94"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="160"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="188"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="203"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="214"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="507"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="579"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="590"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="624"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="637"/>
            <end position="646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="670" mass="73370" checksum="B491C1519D624AD7" modified="2025-10-08" version="1">MHTTPSAPTATTTSKSPYPAKPPSSSTVTSPVIGPTLGTGFPPVVAAVAAVPSQSSLPSRKNSSTMPPPSHHNHHFQPSRSEVSLASSADIDASQQNSQNLSQNPHHSSKKPKSKPGFGRMGRSRKNDKEKEEAALPSRSATSTPVQDDRSVSSGIPALNKNNSYGQSSKDTASKMPSSSSGPSSRNRSRDRGFAKDDSHHDYGHHKPRHHGLGHKDKDKDKSQHHLKGENNGLFSSLKSSGTRAADIFSKGLFGKNARQNSTTEREVPVEDDHYVIKVINLPLVEQTRLTRISKRLEESRDKTEFWMPAFPWRAIDYLNYKGCDVEGLYRVPGSGPQIKKWQRRFDQEHDVDLFEQPDLYDINIVGSMLKAWLRELPDELLPKASQDRISRECAGAQEVPQLLIDELSKLSPFKYYLLFAITCHLSLLLAHADKNKMDYRNLCICFQPCMKIDAFCFKFLVCNWRECWKGCANEAQYIEQEYRLFDAPLPRGLTRTGAVIPASPQTTSTSTTTTNTGANMSTTTATSSNSRNGSSNHTATTTIQIVQLSPKGDSSFPLHPPADIKVASSVASTSVALSDHDTTEERAVSSSGSSKQSAQSLEPVKIRTKKGTVLAPIDASPGSIRSISTTLTSDNEQDKRGDRDNNVLGTPTCEIRPLSPIKPLSPLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI89</accession>
    <name>A0ABR3YI89_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">4-aminobutyrate aminotransferase</fullName>
            <ecNumber evidence="3">2.6.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">GABA aminotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Gamma-amino-N-butyrate transaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">UGA1_2</name>
        <name evidence="12" type="ORF">Cpir12675_006505</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23352"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57706"/>
            <dbReference type="ChEBI" id="CHEBI:59888"/>
            <dbReference type="EC" id="2.6.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.19" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000311">
        <property type="protein sequence ID" value="KAL1887557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004631">
        <property type="entry name" value="4NH2But_aminotransferase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00699">
        <property type="entry name" value="GABAtrns_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43206:SF1">
        <property type="entry name" value="4-AMINOBUTYRATE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43206">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1887557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="460" mass="50062" checksum="AA7FC1DAFD3AA4ED" modified="2025-10-08" version="1">MSVLEPSVSTAVPGPQTQAAIQALGEVFDARAVQIVADYDKSEGNYLVDVDGNRFLDVYSQIASIPVGYNNKRLIAAASSPTMVSALVNRPATGNFPSLAWNDALRNGLMKAAPPGLKYIFTAQSGSEANELAFKAAMMLYMRRKRGLGVEWTDEESSSCLNNAKPGSPELAIMSFENSFHGRGFGSLSTTRSKAVHKLDIPAFNWPKAPFPALKYPLEAHVEENKAEEQRCLDAVEELIKTWASPVTAVIVEPIQSEGGDNHASADFFQGLRDLTKKHGVALIVDEVQTGFGSTGKFWAHEHWNLTSPPDLVTFSKKAQTAGYFFGDELLIPDKAYRQFNTWIGDLARVLVSKAIIEEIQANDLVAQTAHVGDLLYAEIEKLALKYPGGKIANLRGKNCGTYIAFDTTDPAKLIASMRKLGVTIGSCGKSTIRLRPMLIFTEEHIPLLVGALDKALSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ51</accession>
    <name>A0ABR3YJ51_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8035 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006249</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000271">
        <property type="protein sequence ID" value="KAL1888242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058348">
        <property type="entry name" value="DUF8035"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42081:SF2">
        <property type="entry name" value="NIPPED-B-LIKE PROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42081">
        <property type="entry name" value="ZINC FINGER PROTEIN DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26118">
        <property type="entry name" value="DUF8035"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8035" evidence="2">
        <location>
            <begin position="795"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="849"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="419"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="625"/>
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        </location>
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            <end position="665"/>
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        </location>
    </feature>
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        <location>
            <begin position="681"/>
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        </location>
    </feature>
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        </location>
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        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="849"/>
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        </location>
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        <location>
            <begin position="859"/>
            <end position="911"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF26118"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAL1888242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="911" mass="103269" checksum="EDC75329D2C73C33" modified="2025-10-08" version="1">MDDRSHFYQPSPPQHQQSQQSQQQKHLQLPLQLQRSASSAFTNHEMSYATKADYPDYIDEAAFVIATPRTTHPHTHVGGGGSDSTMTSPHLSSQAPYVGSAPHRFPPGQKSSVPSSVNSTTSPPPERGYRSPSTHGTLPVRSRSKSPSSNGKISYVMSDSNRMYGVGSGSTKRSKSHVRGHSYVSPNRDYDRHHPDDFLDSPTSPRADYPHQMNTGASVGGRFNGGDRFDIGGRMRFGSGPTDASESDYQCSTNSVDAYDVSTRSERDPQHQRPVLMYDQGRANLNVTTTTTENARRVPLMGSTRPGPPTYETSPKANQLVMQTSPRASTSNTSSSVYQTMCYTYDMREAEKRKVEDEDLQRLAKRFALKNDANRDKRMLQLEYCDDTSSKRGFGLHPPDPEFDNDYHERPTLPQPPPRDTRDDADRDRRARGGISSNSGNRSEDDVRARKGGRDAMALKDKSQREWNHMAEDQRYKSSQNMTPDDSDFEDRQDDTLGGEDFALVNLTSPDRSAIRDEREVRDGGRKRTKNESPTKRSAQSRARERINWEQERDDGWARQEEGKEKRLRAERERELERERERERERKNREMEREAKAEKEKQRQRDASVAASSRLPPTPPKEPQIKSSIRSSSTSPTTRTKKFGAVGDESRDASEHADSRDKRPELPSASGITTPNSSITPASSSPQPAGSPPLAKSAAAFELASAVSEGDEEDTPRGRTKPTDVPEKKQVRVVSPKREKSQGPKKLKGILKQPSKFPENNDINELPNATGDSSDDRRDRNKELVETGNSIPEGARWTRLTRRIVNREALDMENEKYDIMDDQIIVMRVLSHTEIQAYADATAELRAKRAERRRKHMAHRDDGAESSRRTTRSRNDRNERRRDESAEHDRRREKRRERGERDTYRSERDRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJS6</accession>
    <name>A0ABR3YJS6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CUE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_006128</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000256">
        <property type="protein sequence ID" value="KAL1888564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
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    </dbReference>
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        <property type="entry name" value="CUE"/>
    </dbReference>
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        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="CUE" evidence="3">
        <location>
            <begin position="50"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="153"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="201" mass="22375" checksum="451FE30EB3296C8F" modified="2025-10-08" version="1">MSNEQISLPTIVTFMAVTALVIWKLFLSPTDAADSSPRNNIRDSAAQAQARETNAQRILQMFPQVDRRAVLWDLRRNGNRIQVTSERILSGRLETPPPTFQPVRPAGQGDATPSLEPSAAKAAHQTEEDLISRYKLQDKISVDLASSVPEDSAQAAAAAGKSSAKTWSSNKEDRQALLRKRREDMILQARRKMELKLAERQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKB1</accession>
    <name>A0ABR3YKB1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">E2 ubiquitin-conjugating protein mms2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">MMS2</name>
        <name evidence="2" type="ORF">Cpir12675_006044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000245">
        <property type="protein sequence ID" value="KAL1888760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23807">
        <property type="entry name" value="UEV_UBE2V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBC core" evidence="1">
        <location>
            <begin position="7"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="141" mass="15896" checksum="8FE18B98EFDFE9B7" modified="2025-10-08" version="1">MATAKVPRNFRLLEELEKGEKGMGSEACSYGLEDPEDLLMSNWTGTIIGPPHSVHENRIYSVKMHCGPQYPDEPPTIQFISRVSLPCVNPANGQVDPCQLPCLDEWKRSHTMETVLIELRRYMALPSNKKILQPPEGSTFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKV6</accession>
    <name>A0ABR3YKV6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nuclear transport factor 2</fullName>
            <shortName evidence="1">NTF-2</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">NTF2</name>
        <name evidence="3" type="ORF">Cpir12675_006005</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000240">
        <property type="protein sequence ID" value="KAL1888916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00780">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045875">
        <property type="entry name" value="NTF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002075">
        <property type="entry name" value="NTF2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12612">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02136">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="1" id="KW-0653">Protein transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NTF2" evidence="2">
        <location>
            <begin position="8"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU369002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="124" mass="14036" checksum="24A6CB3BA34029FD" modified="2025-10-08" version="1">MAAGYEEVAKQFVTYYYETFSTNRKGLVTLYRDNSMMTFESASTLGAVNIAQKLEALPFQEVKHAVSTIDSQPTIQDGVLVMVTGQLLVDKEQRPMNYSQTFQLMKDASGDYFVFNDIFKLVYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKX4</accession>
    <name>A0ABR3YKX4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006018</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000242">
        <property type="protein sequence ID" value="KAL1888843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046460585" evidence="2">
        <location>
            <begin position="19"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="106" mass="11132" checksum="AE987CCDA11F7D79" modified="2025-10-08" version="1" fragment="single">MKPLQLLPLLSLPILSTASQHAAGLQERANGEIGPRIVLHPNNDEVMKRAVPAAAAKREESTTTAVATVSDAPAKRQETTSPTIVATVSDAPVKRQEPTSSTVVVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLD5</accession>
    <name>A0ABR3YLD5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome c oxidase copper chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">COX17</name>
        <name evidence="8" type="ORF">Cpir12675_006020</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COX17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000242">
        <property type="protein sequence ID" value="KAL1888845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1130">
        <property type="entry name" value="CytochromE C oxidase copper chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009069">
        <property type="entry name" value="Cys_alpha_HP_mot_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007745">
        <property type="entry name" value="Cyt_c_oxidase_Cu-chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16719">
        <property type="entry name" value="CYTOCHROME C OXIDASE COPPER CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16719:SF0">
        <property type="entry name" value="CYTOCHROME C OXIDASE COPPER CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05051">
        <property type="entry name" value="COX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47072">
        <property type="entry name" value="Cysteine alpha-hairpin motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="74" mass="7544" checksum="2DBEA2549534CC04" modified="2025-10-08" version="1">MSADTSCPIPAASTAVLAAGTDAPSKPKPCCVCKEEKARRDECMLFSKAADPAADCAPAIAAYKACMAGFGFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLR6</accession>
    <name>A0ABR3YLR6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Microtubule-nucleating Tub4p (Gamma-tubulin) complex component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SPC98</name>
        <name evidence="9" type="ORF">Cpir12675_005845</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TUBGCP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000222">
        <property type="protein sequence ID" value="KAL1889296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF14">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="8">
        <location>
            <begin position="229"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="7">
        <location>
            <begin position="535"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="112"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="174"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="880"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="114"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="131"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="880"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="894"/>
            <end position="905"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1889296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="905" mass="101352" checksum="33A4E3D8E1ADAE1D" modified="2025-10-08" version="1">MADNKIESRITNAIDRLVSHLIPNDPDEDESIAQQRHDHCFNVTKTILSSPAASAPLGDVNHASDMIKRKLIQTNPSQALRFSNLYTRLLSLPVLNQKWAILYLLYQLSDSPDPNEPVPITPRPPPLNPRDVSRRQEKDRSPNASPLMRTDEEAQAQAQAAYVAAKEAQLAQAQDNAVKKQTQKEAAKKASEAQRTPVEPEPRRRDVALKSLLLADNYSEVTPNEVTILRDMPFTLQGVPSETQPITQDNVLKIPPTLPPPLVSLLNTLAEPSLLYRKLDTFVNTPAPGLLQQSIRAAISTELRSYLSLIATLEGQIRRALSSLDETVPRGGIGKAGVTLKRCVIWTREATMGLRLLSVIAEESTTKHGGELITLIHNFSSAHGDPTVAAFAERLLVNFTKPFYDILRHWIYGGELSDPYLEFFVKEQTQKLAAADRNKSGGTSIWETKYEMVEAMIPSIITRPFAEKMFLIGKSLNFIRHSCGDSQWVEAYSKAASRELRYGETAKLEAWIDEAYKTTMKQLIDLMDHKFKIFMHLQALKDYMLLGQGDFTALLMESLAPNLDRPANILYRHTVTAQLDHAIKGSNAQYDNPEVLRRLDAHMLQRFHGDIGWDCFTLDYKIDAPVDVVVTEWGLRQYLKVFNLLWRIKRVEFALATTWRKCMTGARGVLQSSDAIVNQTWKSTQGILAEMIHFVGQLQYYFLFEVIESSWDELQRKIHRDGATLDDLINAHTQYLNDITHKGLLGANRNKHAGEAAAAAAASDGGDRTTYTAQLNDILKGMLTFRDSVDGLYSWSVSNFSRHQELGVHGDDEAASLAGPASEFPVLQERLRHLGLYFKSRLQILLGDLAYQPDLDMRFLGVAMNFNDFYQPVKRRVKSVQQQQQGTSATSGGTKEGGGYVGGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLW7</accession>
    <name>A0ABR3YLW7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Kynureninase</fullName>
            <ecNumber evidence="4 5">3.7.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Biosynthesis of nicotinic acid protein 5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">L-kynurenine hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">BNA5</name>
        <name evidence="7" type="ORF">Cpir12675_005942</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>3-hydroxy-L-kynurenine + H2O = 3-hydroxyanthranilate + L-alanine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25143"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36559"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:58125"/>
            <dbReference type="EC" id="3.7.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>L-kynurenine + H2O = anthranilate + L-alanine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16813"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:57959"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="3.7.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 5">Amino-acid degradation; L-kynurenine degradation; L-alanine and anthranilate from L-kynurenine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 5">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the kynureninase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.7.1.3" evidence="4 5"/>
    <dbReference type="EMBL" id="JAWDJO010000233">
        <property type="protein sequence ID" value="KAL1889040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030429">
        <property type="term" value="F:kynureninase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01970">
        <property type="entry name" value="Kynureninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010111">
        <property type="entry name" value="Kynureninase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01814">
        <property type="entry name" value="kynureninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14084">
        <property type="entry name" value="KYNURENINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14084:SF0">
        <property type="entry name" value="KYNURENINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22580">
        <property type="entry name" value="KYNU_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038800">
        <property type="entry name" value="KYNU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4 5" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="3 4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="6">
        <location>
            <begin position="107"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="158"/>
            <end position="161"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="338"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR038800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="469" mass="51573" checksum="ECD4B9B7BB77DEED" modified="2025-10-08" version="1">MELFTRDKAQSLDDSDSLGFTRDEFIIPTRDEIASKKLPAAAFTDSAEYGSATKSVYLVGNSLGLQPRRTHERISQYLDTWRTQGVQGHFKPLEDSPLPTWLNVDDRAAEMIAPIVGAKVDEVAVMQTLTANLHFLLCAFYRPQKDGRHKILLESKAFPSDHFTVETQIRHHGLDTKTSMVCIEPATGGHVLTTEHILDTIAKHASNTAILLLPGVQFYTGEFLDIAAITAAARGQGIFVIWDLAHAVGNVPLQLHEWDVDAAAWCTYKYLNSGPGCIGGLFVHERNASVSTEAHSENAPSGYVNRLAGWWANHKPTRFGMVNNFHPAAGARGFQLSNPSVLDITSLCASLEVFKLAGGMGPLRQKSLLLTNYLETLLDNAVEEQLRELYTILSPRDPERRGAQLSILLSDGLLDAVMASLESEGVLVDDRKPNVIRVAPTPLYNRFTDCFDFVEAFKRALISASSSPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM23</accession>
    <name>A0ABR3YM23_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_005811</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000218">
        <property type="protein sequence ID" value="KAL1889389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF31">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="340"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="364"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="407"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="430"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="12"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="457" mass="49059" checksum="1070A2EF6AB5D08D" modified="2025-10-08" version="1">MAGVDPATRKKVLRVISISLLLDLISFTFILPLFPKLLEYYRDSEAPALAVSPENASQAQIHTQTLLQTILAYLNTYKQSFDRKIDSRHDIVLLGGALGSLFSILQAIASPIIGRISDRYGRRNALLASMTGNIFSVLLWIAAVDFRTFLASRVVGGLSEGNVQLATAMATDISDENNRGSTMAIIGACFSIAFSFGPMLGAYLSTIEMVARNPFATAASVSLALIVLETVYLWACLPETLPSKTTLFSDSSAAGKQKDKPAQRQPDTPVVQRTNSFALLSAIHFVFLLFFSGMESSLSFMTYDLFGFTSANNGRLLGFVGIVASIIQGGVTRRMSPLRCVRIGVVACLAAFMILSRVSTVSGLYAAATCLAITSATVVTGLNALTSFEAHATERGGKLGNMRSWGQLGRGLGPVLFTSVYWWAGRDVAYMMGTMGLLVVLSGVFVGLKSPMRTSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN33</accession>
    <name>A0ABR3YN33_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NB-ARC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000210">
        <property type="protein sequence ID" value="KAL1889608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NB-ARC" evidence="1">
        <location>
            <begin position="4"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="201" mass="22298" checksum="BAEF9EB91732B074" modified="2025-10-08" version="1">MSALFTQVGFQHVALVGLGGKGKAQVALKLAYTVKAKHAEYSVFWLTAASIDEFRNSCKELTLALGINTSDSDDPRMLVKNYLDANMCGIWLLILDNADDTGIFDAVDKESRISTFLPQSKEERIISTTRSKKVSWLAVERDSLELEELSPQDLPTILMRSVEGLNNESHLRDEPSIKNLLDELYHLPLAVAQAADYVAVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YND7</accession>
    <name>A0ABR3YND7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]</fullName>
            <ecNumber evidence="3">1.3.1.124</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SPS19</name>
        <name evidence="6" type="ORF">Cpir12675_005793</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a (2E,4E)-dienoyl-CoA + NADPH + H(+) = a 4,5-saturated-(3E)-enoyl-CoA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:45912"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:85101"/>
            <dbReference type="ChEBI" id="CHEBI:85493"/>
            <dbReference type="EC" id="1.3.1.124"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a (2E,4Z)-dienoyl-CoA + NADPH + H(+) = a 4,5-saturated-(3E)-enoyl-CoA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:61892"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:85099"/>
            <dbReference type="ChEBI" id="CHEBI:85493"/>
            <dbReference type="EC" id="1.3.1.124"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.124" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000217">
        <property type="protein sequence ID" value="KAL1889393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008670">
        <property type="term" value="F:2,4-dienoyl-CoA reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05369">
        <property type="entry name" value="TER_DECR_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045017">
        <property type="entry name" value="DECR2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43296">
        <property type="entry name" value="PEROXISOMAL 2,4-DIENOYL-COA REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43296:SF2">
        <property type="entry name" value="PEROXISOMAL 2,4-DIENOYL-COA REDUCTASE [(3E)-ENOYL-COA-PRODUCING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00026117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1889393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="320" mass="33066" checksum="9E31151B2BD96F86" modified="2025-10-08" version="1">MSAPAPSSTYVSNVWKDGIFDGRVAFVTGGAGTICSVQTRALVRLGANACIVGRNADKTEAMARDLETARAGSKVIGIGRCDVRKIEDLQAAAKRCIDELGAIDFVIAGAAGNFVVPISGMSSNAFKSVMDIDVLGTFNTIKATMPHLVESAKRNPNPSPTGTGTGGRFLAVSATFHYTGMPLQAHVAAAKAGVDSLVASVALEYGPLGITANAIAPGPIAGTEGMERLAGDVAVGEQGKGVPSGRWGTVRDIADATVYLFSDAGNYVNGQIIPVDGASWRRQGSDGAGVGVDSSMKYPDYILKGEISKQIKTGRKETKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNW7</accession>
    <name>A0ABR3YNW7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_005734</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000212">
        <property type="protein sequence ID" value="KAL1889541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39336">
        <property type="entry name" value="PYRIDOXAMINE PHOSPHATE OXIDASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G11440)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39336:SF1">
        <property type="entry name" value="PYRIDOXAMINE PHOSPHATE OXIDASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G11440)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1889541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="231" mass="25414" checksum="BDCF2F3B240A0775" modified="2025-10-08" version="1">MIEPRLNAHFRVISPNKVAYIDRTGSGCETIAHAYEPCNARLTLLFISFGRAPRILRLFCTSSVVEWDQPAFEGLVCQVADGKRSVFDGARAVVFCQVFKVQTSCGYGVPMIKPQLYNGSLLLQEATSDEGQAATQRLIDGLSVFADRPTPDNWVAKNVASNTALQYQVDNNLQSLDGLPGLPSAQQNYFSSCLQNLETDRLVLHLMPPDDLGEAMQSERGALSQPPYSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPD2</accession>
    <name>A0ABR3YPD2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_005618</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000202">
        <property type="protein sequence ID" value="KAL1889850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053178">
        <property type="entry name" value="Osmoadaptation_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38111:SF9">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38111">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="10"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="52"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="77"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="96"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="113"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1889850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="521" mass="58077" checksum="2D81302D6B05D7E0" modified="2025-10-08" version="1">MVGVPGKYKGCETCRRRRVKCDNMRPICRKCVSTGRSCEGYERQMIFITATPEDGGRCSSHPPRSTSKKALRGDSASVKSHGSRNSQEGNSPSPPASASSSHSISQQLSLPSASISNGSPISAPTLSPSEPLRPAWDDLIFLSNKHSYYTTQIVSLQTKLAHVNREVSSSIFSPPSYVLPDFRPASNSGAFSVSGQCIVNIDSASEPKSGLCVFLYEPNNCSSSPPETSQWKSPHDYMNNVQAAGPQAVTLFPAHHFFSRVYRPSNTAWSLLTRKATHLAQRDWVTTPWQYYPKSLIDRLFDILVQIPDLLERADATSHHVSTQDRQLKIQNLLTRCLYIDRQLNEWCAIATQDPEDSHRHSYWISRLPQTQASMPFSETFAFINAATAIGFLYYWMGSLLLNRCILNLHRLFFQPAVDYNMYPPVLPVELNIDVSNYQRDGIFAANICCSLDFALNASTQPDVLAGPLAVADMYFKGFQGTGQSQIETAWCDGFRQRMTAKGQGIVSVVASRHWDEYGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPF7</accession>
    <name>A0ABR3YPF7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_005507</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000191">
        <property type="protein sequence ID" value="KAL1890191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF24">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CHK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="195"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1890191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="400" mass="44695" checksum="26673791FA3C45C7" modified="2025-10-08" version="1">MDYKHGYAFRLVATTGQAAEAIERGKRGGGAFCECPEKAVRISNDRDTANTAQFSVPSYGFKTYRDNFIAFRFGINSFVQPVLSPRCSPCGKQLVVISYRMVTAQVFIEDYTDTLDAIVFTSETHQPLKQEGKLYLAPTMDHKFYVKDTECAFSLVWNDNWLEAVRRHLKRIPADLLIPPRESSIYKKKTFKFRYVELETIGTGATSQVIKALDVDSGQVVAIKQTETSRNSHLQKVLLEEALMLKQLCHPSIVEFIRVDELENGVDLTLACKPLSMQQAIELKLFKDNLNAHSNLFMHQMLEALAYLSSSFIVHLDIKPANILCAPARQRNVWNFFLADFGLAMPTGNPLCSAGTPGFAAPELSSSPACTSCHPSMDTYSLYLTLVVLRNPAFSMESSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPP9</accession>
    <name>A0ABR3YPP9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tryptophan synthase beta chain-like PALP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005624</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000202">
        <property type="protein sequence ID" value="KAL1889856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01561">
        <property type="entry name" value="CBS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050214">
        <property type="entry name" value="Cys_Synth/Cystath_Beta-Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007989">
        <property type="entry name" value="PRK10717.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10314">
        <property type="entry name" value="CYSTATHIONINE BETA-SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="2">
        <location>
            <begin position="42"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="375" mass="40580" checksum="A0865534D6E7862C" modified="2025-10-08" version="1">MFRCGVRGFATSVRRALPGFAFEQTVRSKGLSLAQGTVNGLTEAIGNTPLIRLTRLSEELGRNILGKAEFMNPGGSVKDRAALFVVQDAEKRGLLKPGGTVVEGTAGNTGIGLAHVCRSRGYKLVIYMPNTQSQGKIDLLRLLGAKVYPVPAVAFDNPMNYNHQAKRHAKSLDNAVWTDQFDNRANRQAHYETTGPEIWHQTNGKVDAFTCSSGTGGTFAGVMGYLKDQSKGKVKAYLADPPGSVLHSYVQSGGKLAERSGSSITEGIGQGRVTDNMAGEIESVDGSFQISDEKTIEMVYRCLDEEGLYLGASSALNVAAAVEAAKEVEQGQTVVTILCDGAYRYADRLFSRKWLESKDLIDAIPKHLHKYIVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPV5</accession>
    <name>A0ABR3YPV5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">E1 ubiquitin-activating protein</fullName>
            <ecNumber evidence="5">6.2.1.45</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">UBA1_1</name>
        <name evidence="5" type="ORF">Cpir12675_005604</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ubiquitin-activating E1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.45" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000201">
        <property type="protein sequence ID" value="KAL1889916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004839">
        <property type="term" value="F:ubiquitin activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01491">
        <property type="entry name" value="Ube1_repeat1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01490">
        <property type="entry name" value="Ube1_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.180">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, FCCH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.80">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12550">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2660">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, SCCH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.60">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, UFD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032420">
        <property type="entry name" value="E1_4HB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032418">
        <property type="entry name" value="E1_FCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042302">
        <property type="entry name" value="E1_FCCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018965">
        <property type="entry name" value="Ub-activating_enz_E1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042449">
        <property type="entry name" value="Ub-E1_IAD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038252">
        <property type="entry name" value="UBA_E1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019572">
        <property type="entry name" value="UBA_E1_SCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042063">
        <property type="entry name" value="Ubi_acti_E1_SCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018075">
        <property type="entry name" value="UBQ-activ_enz_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000011">
        <property type="entry name" value="UBQ/SUMO-activ_enz_E1-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01408">
        <property type="entry name" value="Ube1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF4">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16191">
        <property type="entry name" value="E1_4HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16190">
        <property type="entry name" value="E1_FCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09358">
        <property type="entry name" value="E1_UFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10585">
        <property type="entry name" value="UBA_E1_SCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01849">
        <property type="entry name" value="UBIQUITINACT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00985">
        <property type="entry name" value="UBA_e1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-activating enzyme E1 C-terminal" evidence="4">
        <location>
            <begin position="900"/>
            <end position="1028"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1889916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1036" mass="114957" checksum="10C258CFB9503455" modified="2025-10-08" version="1">MAEVDMKDQPTGADNGAAVSAPEIDESLYSRQLYVLGHEAMKRMGASNVLVVGLDGLGIEIAKNVALAGVKSLSVYDPKPVTLVDLSSQFFLRDADISKPRDEVSAPRLAELNAYVPIHVHKTASKTLDSDLTGLSKYQVVVLTDTPLKQKIAIADFCHKQNIYVITAETFGLFGSIFCDFGNNFTVTDPNGEAALSGIVVNIDETGLVSTLDEARHGLEDGDYVTFTEIEGMDVLNNSEPRKVTVKGPYNFSIGDVSTLGEYKKSGLWQQVKMPKVLDFKNLSSALKDPEFLIADWAKFNRPQQLHVGFQALHTFAEDKGRLPAPFSKDDAADVFKLSQQIATEAEIEVEFDTNLMTELAYQATGALTPMAAFIGGIAAQEVLKAVSGKFHPVKQWMYFDSLESLPVNTPRSEELCKPTGSRYDGQIAVFGREFQAKIANTKEFLVGAGAIGCEMLKNWAMIGLGTGPEGKIIVTDMDSIERSNLNRQFLFRSHDVGQMKSDSAAKAVQRMNPDMEGHIQSHKEPVGKNTEHIFNEQFWAGLDGVTNALDNVAARQYVDQRCVFFRKTLLESGTLGTKGNTQVVLPNVTESYASSHDPPEKEFPMCLVRSFPYRIEHTIAWAKEHIFEPHFVQRPQTVNMYLTQADYISKALQQGGNQSNVLKNIRDSLTIDRPRTFEDCIAWARLMFEKLFVNDVQQLLYTFPKDATTSSGTPFWSAPKRAPDALKFDATNPTHFSFIVAAANLHAFNYDIKSPGDDKQVYLRELENVIVPDFSPSSSIKIQADDSEPDPNASSSFGDESEIKYIVNSIPPPSELSGFQLVPVEFEKDDDSNYHIDFITACSNLRAENYKIETADRHKTKFIAGKIIPAIATTTALVTGLVVLELYKIIDGQSDIEKYKNGFVNLALPFFGFSEPIASPKVEYKGPNGKVTLDKIWDRYEVQDITLQELLDDFEKRGLAISMLSSGVSLLYASFQPPSKTKEKMGMKLTELLETVSKKEIPSHQKDIIFEIVADDADGEDVEVPFITVHRREEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YST9</accession>
    <name>A0ABR3YST9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin-like 1-activating enzyme E1A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">AOS1</name>
        <name evidence="9" type="ORF">Cpir12675_005140</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ubiquitin-activating E1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000164">
        <property type="protein sequence ID" value="KAL1891014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004839">
        <property type="term" value="F:ubiquitin activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01492">
        <property type="entry name" value="Aos1_SUMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000011">
        <property type="entry name" value="UBQ/SUMO-activ_enz_E1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF162">
        <property type="entry name" value="SUMO-ACTIVATING ENZYME SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01849">
        <property type="entry name" value="UBIQUITINACT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="8">
        <location>
            <begin position="116"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="58"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="482" mass="52089" checksum="4532A642B39F28FA" modified="2025-10-08" version="1">MNSQPVNQPLNHEPVSSAQQQKFLETPSGADASTKPDGPSIDQPALPRSAPIVPMANAKSTRPTADPSQPSVAALSGPFLPPTSDTLPPPHFVVVPNAIPKNKVDSGITDDEIALYDRQIRLWGMNAQKRIQSSRILLITMRALGNEIAKNLVLAGIGSLTILDDGLVNEADFGAQFFLHEEDLPLGLNRAQAALPQVQKLNPRVKVVADPEGVTRKDNHYFANFDVIIATDLTPATLNFINTAARVHGKAFYAAGVHGLYGYIFNDLIEHTFVIRRDAGNVAAKIGPESRTRSIIDVKVSREDGKPIEHVTKQELYSTWFLASDVAGLPEEIARNARRKRAVSPILSCLRGLWEFQTAMERLPSPVAADLKMFVKTVQEKHAALDLPAETIRSETINSFLQGLGTELPAVSAVLGGQLAQDVINVRGQTQQPIQNMVIFDAGSCESSVYSLHPEGSVGKAQLRASEPEVVAKVAAKNGVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT87</accession>
    <name>A0ABR3YT87_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000163">
        <property type="protein sequence ID" value="KAL1891112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="68"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="186"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="285"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="346" mass="37882" checksum="F956C04F05B9BC61" modified="2025-10-08" version="1">MLPPIDESVLEKNTNFKVLYTTLTTAVLNGDGTTTALWSATEHQKVVDELDHHRLKEARRHLLTNAIATAAPQEEPKEPQSKSIPSSSRREPASELSTSQALPDDVLDLLLLLPSLITSPEPLSSEATSLLLSSPPLANLDSLLPQCAPLVSANLQASALGLSRVTHPGTNPSYLHRNIANLPATVASLRASLEKQKSDLAKARLAAQAEVVNILKRRTQALTQLVRALEAKHGAVARSAEHSAAELALQAQIAEAEASLALHRVRKDIYSTEVCSALRNYGGHLQDARLRLEEALRARKMELAEYGVGVEGQEGKERFMREAAKTYREMSRQMEDIEGDLERLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTE7</accession>
    <name>A0ABR3YTE7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL3</name>
        <name evidence="5" type="ORF">Cpir12675_005029</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000158">
        <property type="protein sequence ID" value="KAL1891239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.960.10">
        <property type="entry name" value="Ribosomal protein L3, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045077">
        <property type="entry name" value="L3_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044892">
        <property type="entry name" value="Ribosomal_L3_dom_3_arc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_uL3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_uL3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11363">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11363:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1891239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="391" mass="43910" checksum="B1768DA73EE71E97" modified="2025-10-08" version="1">MSHRKYEAPRHGSLAYLPRKRAALHRGKVKSFPKDDPKKAVHLTAAMGYKAGMTTIVRDMDRPGAKSHKKEVVEAVSIIDTPPMVVVGLVGYIETPRGLRSLTTVWAEHLSDSLKRRFYKNWYKSKKKAFTKYAKIHSETTGASVTRELERIKKYCTVVRVLAHTQINMTPLKQKKAHLMEIQVNGGSIADKVEFGHGLFEKTFDISSVFEANEVVDVIAVTKGHGYSGVTSRWGTKKLPRKTHKGLRKVACIGAWHPAHVQWTVARSGQDGYHHRTSVNHKIYRIGKADDEASGSTAVDITRKKITPLGGFVRYGEVKNDFVMVKGSIPGTKKRVVTLRKSMWVHTSRRALEKIELKWIDTSSEFGHGAFQTPAEKKQYQGTLKKDLVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTG3</accession>
    <name>A0ABR3YTG3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_005027</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000158">
        <property type="protein sequence ID" value="KAL1891237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF12">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="332"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="356"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="381"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="421"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="458"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="492"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="54"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="13"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1891237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="536" mass="58177" checksum="EEA8DCCD7B8A051E" modified="2025-10-08" version="1">MSDDGAHEALIQRTPHDREDHDHVHYHSHHEPDALSGHKGGTSGDAPNAFVWMLTAAAGISGLLFGYDTGIISATLVSVNKDLSNRILTLLDKSLITSSTALFALLISPFSSVLADRFGRRRVILIADSLFITGAIVQAVSHSVLAMVLGRCIVGAAVGAASFVIPLYIAEIAPSAHRGRLVTANVLFVTLGQVIAYVTGWILAQYGNRETAWRWMVGLGALPAMLQLLLLILMPETPRWLVRNGNVSLAKKVVLRVNGFSVYAADAVIRDIEVEVRNEQEETAALHSRRERLASSFSAIPDSWYELFNVPKNRRALAIACLLQGLQQFSGFNSLMYFSATIFTMVGFPVPTLTSLTVAVTNMAFTVVALFIIDRIGRRRMLLWSIPLMIVGLVISAYGFSRINIMGTSSTPSSPSILPSSSAALILVSFMVYVSGYAIGIGNVPWMQSELFPLSVRSLGSGVATATNWGANFVVGLTFLPMMDSLTPTWTFALYAVICAAGQFLIWRIYPETAGLSLEEATSLLDHGWGVNREDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTI5</accession>
    <name>A0ABR3YTI5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">AP complex subunit sigma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">VAS2</name>
        <name evidence="11" type="ORF">Cpir12675_005020</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000157">
        <property type="protein sequence ID" value="KAL1891335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14831">
        <property type="entry name" value="AP1_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044733">
        <property type="entry name" value="AP1_sigma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016635">
        <property type="entry name" value="AP_complex_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11753">
        <property type="entry name" value="ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015588">
        <property type="entry name" value="AP_complex_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="10">
        <location>
            <begin position="3"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR015588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1891335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="155" mass="18244" checksum="3A34B24DC0E41FEF" modified="2025-10-08" version="1">MAIQYLILLSRQGKVRLAKWFTTLSPKEKAKIVKDVTQLVLARRTRMCNFLEYKDTKIVYRRYASLFFITGCASEDNELITLEIIHRYVEQMDKYYGNVCELDIIFSFTKAYYILDEILLAGELQESSKKNILKCISQQDSLEDMEVEDEVTRIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU87</accession>
    <name>A0ABR3YU87_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">M protein repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004969</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000154">
        <property type="protein sequence ID" value="KAL1891457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159">
        <property type="entry name" value="CENTROSOMAL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159:SF31">
        <property type="entry name" value="CENTROSOME-ASSOCIATED PROTEIN CEP250 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="400"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="459"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="215"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="474"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="582" mass="64218" checksum="7462EADB8084F34C" modified="2025-10-08" version="1">MDEKQRAEKLAAARKKAQQMKKAKKEKKDKVAEGTADKPVDQENPKKEDAVDAKPSKAGNNKAPEEPSEDIEPADDTAAATTITSDDSSDKPPADNNDASSNTASLAEQSKIRSSSFRKNSTTSMSPPPQSAGLAGVAEAEARAADIYRKQTARIEELETENKRLGKDAADADKRWKKAEEELEDLREQDGENNDDDEVTKLKEDNESLERQIKQLQSQLTRRQSSSAAPLPAGLSPTALQEQIDSKTTIIESMEAELSTLRGKLERTESGSSSEKEQITALKEKLLSAEKKAEEAQNELVGLKKNVDRTAEKAVRESSERTSIETKMHTLENELAEKQAALVEADKKVDALEKKVSALTTLHKEQETRSQGLRKEKEAADKQLLDLKLKLERADNENLRLKTRKSTDGGGGLDDDGVDELEDEGRRLLEQQVRDMEAEISELRRGIWRTRRKSLASGADGTNAAFHDVDLNSAPPTHSHSRKPTQTASGFGEFLTSGLNALAGTGGHDGDLEEDGSFLSDDDEAGLDFDEDAFRRAQAEEAKVRLERMKELKRGLKNWEGWRLDLVDTRKGVQGFGDVFEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV44</accession>
    <name>A0ABR3YV44_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Prion-inhibition and propagation HeLo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000142">
        <property type="protein sequence ID" value="KAL1891920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1020">
        <property type="entry name" value="Prion-inhibition and propagation, HeLo domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029498">
        <property type="entry name" value="HeLo_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038305">
        <property type="entry name" value="HeLo_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14479">
        <property type="entry name" value="HeLo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prion-inhibition and propagation HeLo" evidence="1">
        <location>
            <begin position="8"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="202" mass="23911" checksum="0090C37CB23B8F4F" modified="2025-10-08" version="1">MDPISFTAGIFPLFKSSMDNFKIIKDASNMRSNLRDDLLVLKGYETKLKDWSKDFNVKKPDFGAPDSNKTQRTTTFMILARINLHLSKCDNRAKLYDLRKNISLQAMEKAAKEDKHIAKYLEEYEHKTCFLRRFFRSMWWAVYHRENFQERIGELLGALWTVLPPPDKKKKIFVKLDENISKDILNWISPIIPRQIHNDKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV58</accession>
    <name>A0ABR3YV58_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000149">
        <property type="protein sequence ID" value="KAL1891658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02883">
        <property type="entry name" value="NUDIX_Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43736">
        <property type="entry name" value="ADP-RIBOSE PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43736:SF1">
        <property type="entry name" value="DIHYDRONEOPTERIN TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="37"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="244" mass="26902" checksum="7A1C20DB2E953852" modified="2025-10-08" version="1">MAPLMLRPDLPLNFPSSLEGFDKPASVFIKDHGLDRLAGIASASVVFDSSGRILLLQRAAHDSQPGTWESPGGGVEASDQSVLYASARELWEEAGLVGTRIVRVVPVHECGANAALPGLTSSLFPDGDADWEFQNVASYFANRSGSKIFCALAFQFADIEPGTQVTLDSNEHQDFKWVTEEEMLNERMEDGFEIPIAGRNMKDMLKQAFKIRRESEETQDRSWGKKTELECISKSLGHTYMISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVA5</accession>
    <name>A0ABR3YVA5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004812</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000145">
        <property type="protein sequence ID" value="KAL1891807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="200" mass="21902" checksum="DBFA7E9A30793243" modified="2025-10-08" version="1">MTPSPLAHSATTPRFRDSRDLERGSIDLSFVPQGKPISHLSPLPQRNWEEAPTVHFESASPMESTEDTAPLSHANKAVNETGPGLRPTPNVTTTVYASPQPGRRFNSSPKTVSWWRWRPRKHAVQTSCSQHGFSRQKRRICGLQWSSFLIVAAVVLLLSVSAITSIAVSMSGSKDGNAINYPKMDSTNSSISTPGYPPYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVM1</accession>
    <name>A0ABR3YVM1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial outer membrane protein OM14 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004569</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000132">
        <property type="protein sequence ID" value="KAL1892416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039454">
        <property type="entry name" value="OM14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38402">
        <property type="entry name" value="MITOCHONDRIAL OUTER MEMBRANE PROTEIN OM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38402:SF1">
        <property type="entry name" value="MITOCHONDRIAL OUTER MEMBRANE PROTEIN OM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="189" mass="19481" checksum="67E727171B8AD42E" modified="2025-10-08" version="1">MLALRSKESPPHQHIYYNIASIIMSYADAAAKGPKQSSKEAAAAPVPAVVSRTDDTHALIDVDSPTVRTVPNDFLERDVQTSTQAARLEREAAAAEARKVAEKKAAAANERRSAAAASAASQAEGRAVADATLGTGALILANFALLLGVGAAAHYFGADHGRWTPSWRNAGLGVGVAAALGLGESVLVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWI1</accession>
    <name>A0ABR3YWI1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="6">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">DBP6</name>
        <name evidence="10" type="ORF">Cpir12675_004428</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="6">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000125">
        <property type="protein sequence ID" value="KAL1892696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17956">
        <property type="entry name" value="DEADc_DDX51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="348"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="686"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="453"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="637"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="34"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="147"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="203"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="220"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="242"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="461"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="637"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="654"/>
            <end position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1892696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="873" mass="93287" checksum="A7ED5B282A0079B8" modified="2025-10-08" version="1">MYARWVPPTASSGARASSSATLTPAPETSASRRTFGEYEEQGKADMVEEGTETEQAIPSLAASNGFGYARWTPGAPASSGVTTLKSKPLLKRRKVDTSSEEEPSSGEDSSSSDESSEDEKKSESNSDSDSDGDGGDSDSSDGDSDTSDSKAHNNDNPKIEPGVDSCSENIEMDVDEEAKPDNPIILDADTMDLDNEVGELIAKRPKKEKKKAKQQITSDSEAKDAMSKHKAVMERKAKSLHLAQTQATAPKSGSSLDSESDNEKHGLEPLPQPEVPLSDEVGPANGTSTTFETLPAWLAAPIRVSATTRTSFSELGFSAAATARLVSKGYTDAFAVQTATIPLLTPSARPGGHDGDVLVAAATGSGKTLAYALPLVRDISAGVVTRLRALVVLPTRELVRQAAEAFEVCAGAFDGANSGGKRVRVGVSVGNQSLKYEQSVLLERRERVAGLEDMETTSLDNGDDDGLRDEEEEEKRAAECAADYLWRVDVLICTPGRLVDHLRHTPGFDLAYLRWLVVDEADKLLAQSFQDWLGLLTERLAASAGVFSARDHPGCGISGVRKVVLSATLTRDLSLLAGLGLRHPRLVVLEGGKGGDGEALQHVLPEGLEERVVRLKDGAMKPLYLVEVLKRLAGERMKDEKKEGKERKNNATNSASSSSESESESGSSSDLDSDSSSSSSSCSSSDSDSNVSKTPKQRGSAKAFCSTVLIFTKSNESALRLTRLLTLLSPSLAPIISTLTSSTVSSARRHILRSFSSRTIRILIASDLVARGVDVPRLDHVVNYDLPASLAGYVHRVGRTARAGRAGVAWTLLPDNESGWFWGRIAKAKDVGRSRKVDRVRVGGEDGELPEADIARYEEALQELGRMARGQQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX11</accession>
    <name>A0ABR3YX11_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histone chaperone</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ASF1</name>
        <name evidence="12" type="ORF">Cpir12675_004530</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Interacts with histone H3 and histone H4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the ASF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000130">
        <property type="protein sequence ID" value="KAL1892447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1490">
        <property type="entry name" value="Histone chaperone ASF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006818">
        <property type="entry name" value="ASF1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036747">
        <property type="entry name" value="ASF1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017282">
        <property type="entry name" value="Hist_deposition_Asf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12040">
        <property type="entry name" value="ANTI-SILENCING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12040:SF0">
        <property type="entry name" value="HISTONE CHAPERONE ASF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04729">
        <property type="entry name" value="ASF1_hist_chap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037759">
        <property type="entry name" value="Histone_Asf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101546">
        <property type="entry name" value="ASF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="157"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="168"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="203"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR037759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1892447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="262" mass="28869" checksum="D6DB77F26CC40639" modified="2025-10-08" version="1">MSVVTLLGVRVLNNPAKITDKYVFEITFECLEPLDKDLEWKLTYVGSATSDQYDQELDTLSVGPIPVGVNKFVFEADAPDTSRILDADLLGVTVILLTCTYDGREFVRVGYYINNEYDSEELNADPPSKPLIERIRRNVLAEKPRVTRFAIKWDNEASAPAEFPPDQPEADMAPDDEEYGADEADEEEEEGVEAVEAAGDDVPMAEETAEGEISDDGSEDIEGESEEEFDEEEEEEEEAAGGDVMDVDMADAKPQAAVSAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX70</accession>
    <name>A0ABR3YX70_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dolichol-phosphate mannosyltransferase subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_004516</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the dolichol-phosphate mannose (DPM) synthase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DPM3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000129">
        <property type="protein sequence ID" value="KAL1892544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013174">
        <property type="entry name" value="DPM3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16433">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16433:SF0">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08285">
        <property type="entry name" value="DPM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1892544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="94" mass="10310" checksum="F2C24F91092E117F" modified="2025-10-08" version="1">MGVTRAQQVAIFGMTALLGYLALLLEFVPLPPVVKTEIVPVLPFWALVSFGAMLLFRLGLGVFTFNDVPDAYDELMGEIDLAKKDLHKMGVDVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYC7</accession>
    <name>A0ABR3YYC7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Anaphase-promoting complex subunit 13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_004309</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the APC13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000118">
        <property type="protein sequence ID" value="KAL1893075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008401">
        <property type="entry name" value="Apc13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28526">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28526:SF1">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05839">
        <property type="entry name" value="Apc13p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1893075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="98" mass="11143" checksum="530994AAAFE528BA" modified="2025-10-08" version="1">MVYGCFNYVHMHQQRNADNFEDMCKDKLPADEIYVPPQHQPINPEDEDDVVPDQHAAFGITKATQNVKETAWKDFGLGRLMSKGPMLGKTPSVKNLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZP0</accession>
    <name>A0ABR3YZP0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_004135</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000111">
        <property type="protein sequence ID" value="KAL1893397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.620.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052557">
        <property type="entry name" value="CAP/Cytokinesis_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056409">
        <property type="entry name" value="Ig_CYK3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46333">
        <property type="entry name" value="CYTOKINESIS PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46333:SF2">
        <property type="entry name" value="CYTOKINESIS PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24584">
        <property type="entry name" value="Ig_CYK3_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="10"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="122"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="261"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="749"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="824"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1019"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1514"/>
            <end position="1607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="154"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="261"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="324"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="351"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="379"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="426"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="461"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="499"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="535"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="553"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="589"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="620"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="692"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="783"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="827"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="851"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="888"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="963"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1019"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1049"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1514"/>
            <end position="1541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1544"/>
            <end position="1559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1642" mass="179140" checksum="44414BC381447EAC" modified="2025-10-08" version="1">MAAPPPLPTTFPCWCRAVYSWGGEGKRDLGFMEGDLIECLNAGDGSWWTGRLYRDRRTVGSFPSNFVEVLPESFRPMTRSVSPLPANNTPAPGATGTSKNKSFRKPFEAYAKAPHYTTAKQPVTYVGGGKEPLAPKKEVPPPKTVSLARKNRDSAPNSSPAQMANRMNTTYGNNSANTRSAGSHSTRQSYESNNRAVSPAPPLQTTYIPRSVSPVIHHQGYTPSPVAPPSRGYSGHEMTQASHGYVSREASPAVQGYHNRSQSQYMPQGNSSVQTQYRQNSASPAPGMQSQQSYYRGSSPAPTALQQQMVPYNSRRSVSPAPPQQNYMSQSHSPVPFSQYDQRNMRRSVSPAPTQAYHSNGMQRSASPVPPHDFYGGSMQRSVSPAPSQHQYRNNSIQGSASGSYHDPYHSNKMQRSASPAPLQNYYGNGMNQSGSPTPPHPKYHKNMQQPVSPAPPPSQYYNNGNMQISRSPDPFITDYAMDRSVGQYRPESRGVSPGPNNYNTYSRAASPAPLNSYSQQNDQYRRAASPAPLRQNSYDQRSISPAPPPPSHQNTYMAQSPSPVPSPSRNLSYQNDQRFRPYSPQPPTHGQQQLQSPSNASGGPPPPPPPHRHVARRGSATSYIGSSDVSRQVSNTSNMGPNISRHGSQASYDRSTVNQISRHGSQTSCVDPHSSRSNGPPLSNDRFRAYSTVSTSALQGQNRFQPQTPRSTSPMPPPNLTPSPLREAMDGVMEQLETLRMSRVMDGADPEAHWSPESLEMVSRQSRKESNARPQTAMGLSAQDSGYETWSAGSSQAASQNDKPVEKSPLPELSSYVERMEKSLEQMHQQTARSEESSQPLQPIKKTHTFDSVQLPTGTSKESDATPSTPSRKIRTRKSAYDILNRTFTTKTTATNASSTTQNTTTTSTSTSDRSLMSGASAGALSATSAGSFERHRGRAQSALGVHKTDAERPDSPFTGVTYHSSHASNASPTRPQSQLAWQDEAPGLGGLVQPRTPKRSIFKKLLDSAKTGVASGRSSIAFTGGDKSSPTRNSPIRGGAASRGLHTSAGNTANSGGSSLAFGSRNSPFGRDAARDMGANKSVDWVQVRRDVNRSNSLSRIERNERMDRARMLDYPAINAVDELYSSMHGDEGADGNPVQNPIHIPSLNLNLVDKNSRFLANIPSSADAAQIATGYVCRPYRSDVQKLRAIFTWVSEKICWEEAFEGAVDTRRTLETKRGCPEEYATLVIKMCQAVGIECELVHGYLKTPGEGLDAGNLPRSNHWWNAVVVDGEWRMMDTCLASPSNPSRAKYSSVGSSSADFFWFLTPPSEICWTHIPEHHGHQHFCQPVAHDVLFNLPTVCPPFFRSGIEMVDYNSSVGRIQGMEMVQLKVNVPNDIELAAEAEVSGFSRDNDGDMFENGEIVHKRALAQAEWYNGVKRYTIKALLPGDEGFGVLKVYAGKRGLMHTIRDIPHPLAFAIPIVHSGENPPYDFVTRHPTPHAQRHDIYVVQPQCQRLALNNTFVFAIRQHPSTSHTSGPQSVLTPSSNPDGGAQSYNRPGSAMSISAASSNPSSASGTIGGKKPAKLAIQTPGGKILRLMRKEERKGISTSSSRAGDDDTSDGGTWETIIKCSETGTWRGLVLADRTARWCVFAEWTCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZR6</accession>
    <name>A0ABR3YZR6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Vesicle membrane receptor protein (V-SNARE)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SNC2</name>
        <name evidence="5" type="ORF">Cpir12675_004121</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000110">
        <property type="protein sequence ID" value="KAL1893422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15874">
        <property type="entry name" value="R-SNARE_Snc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001388">
        <property type="entry name" value="Synaptobrevin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016444">
        <property type="entry name" value="Synaptobrevin/VAMP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45701">
        <property type="entry name" value="SYNAPTOBREVIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00957">
        <property type="entry name" value="Synaptobrevin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005409">
        <property type="entry name" value="Synaptobrevin_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00219">
        <property type="entry name" value="SYNAPTOBREVN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0675">Receptor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="4">
        <location>
            <begin position="34"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="121" mass="13492" checksum="997ACD8F3753DA9B" modified="2025-10-08" version="1">MPEHQDAPYDPYIPSGGKAAAGSNTQNANNGDPRTQALQAQIDDTVNVMKQNIHLATQRGERMDSLQDKTDNLAHSTHSFRRGANRVRKQMWWKNMKMRIWIGVGIAILIAIIVVSVVVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZS8</accession>
    <name>A0ABR3YZS8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_004211</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000114">
        <property type="protein sequence ID" value="KAL1893233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17356">
        <property type="entry name" value="MFS_HXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF47">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="268"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="301"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="326"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="372"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="409"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="440"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="14"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1893233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="522" mass="56821" checksum="B5D401ADD2475647" modified="2025-10-08" version="1">MGVHFPKITNTYFVALIATVGGMLFGFDISSMSAIVITDQYMDYFDNPHGVVQGAIGSALAAGSVVGSLMAGPISDRWGRRDSIFFACFWWLAGTAIQVATNGIGSLIAGRVLNGVCVGITSSQVPVYLAEIAKRERRGRIIIIQQLAIEWGIFFMYFIGYGCSHIAGTASFRTAWGSQFIPCVLLMVGLPFLPRSPRWLAKVGRDEEAIRTLADIQANGNLEDPLVLAEWHEISTVLRAEQEANLGYKSFVVNGMWKRTLAGMSVQAFQQLSGANAIVYYITYVFQMAGLKDNANLLASGVQYALFIIFTGIMFFFIDKTGRRPLLIYGALGMALCHFVVAAVLGGFGTYVPGGVDGNPNVLITVSGNASHVVIAFSYLLIVVYALTLAPVAWIYAAEVWSLGTRATGMALAAVANWLFNFALGMFTPPAFRNITYRTFIIFGVLCIVAAIVAFFTYPETCGKSLEEIEQLFAPGAPMPWKTTKGTPRTEAEIQAIQDKQYKADDGEYKGHMTTIEKKVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZX3</accession>
    <name>A0ABR3YZX3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mitochondrial division protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SWD3</name>
        <name evidence="10" type="ORF">Cpir12675_004079</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in mitochondrial fission. Acts as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat MDV1/CAF4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000108">
        <property type="protein sequence ID" value="KAL1893471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059122">
        <property type="entry name" value="Beta-prop_WDR5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25175">
        <property type="entry name" value="Beta-prop_WDR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="93"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="135"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="WDR5-like beta-propeller" evidence="9">
        <location>
            <begin position="208"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="215"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="257"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="300"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="390"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="46"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00039789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00043913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF25175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1893471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="533" mass="57727" checksum="60E2C5837CA1E0D0" modified="2025-10-08" version="1">MSTDRVTRSRSRSPIDSNEHFFSSSPSQANSSCHESQRHTSRKRQFTTSSTSRSRHSSPPQTPSASTSRSPSVSATPPSPLSPTPIFQPRFILHGHTKPVSQVRISPDGAWIASASADTTIKIWDAQTGDHVDTLVGHLAGVNCVAWASDSRLLASGSDDKAIRLWDRLTGQPMLTARGVIAARHLEQQIQHDNGDAGLVPNAKHTNNLRVMEPLVGHHSYVHCLAFSPKGNVIASGSYDEAVFLWDVRAGRLMRSLPAHSDPVSGIDFSPDGTLVVSCSTDGLTRVWDATTGQCLRTLVHEDNPPVANVCFSPNGRFVLAFSLDNCLRLWDYVAGKPKKTYQGHRNEKYALGGQFGTFSPRPRCASHHSLETDAHPSTTIDIDDSAIAYIASASEDGGIVLWDVKSKMQIQRLAAHDGVCIWVDVHGDTIVSCGLDGTVRVFHSVVPVHEAKDEPELGCEALPINKTTSGIANGTANSNTAPSVSPSLQAYYSDDELDHNIVGTGLPEDEEDMIRLVPTDGFRDDDEIIPDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z094</accession>
    <name>A0ABR3Z094_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Vacuolar membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_004151</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000111">
        <property type="protein sequence ID" value="KAL1893413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051009">
        <property type="entry name" value="PRM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36089">
        <property type="entry name" value="CHITIN SYNTHASE 3 COMPLEX PROTEIN CSI2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36089:SF1">
        <property type="entry name" value="CHITIN SYNTHASE 3 COMPLEX PROTEIN CSI2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047130505" description="Vacuolar membrane protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="348"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="369" mass="38137" checksum="53577738936DA65E" modified="2025-10-08" version="1">MADSKFLLSAAFLVAFTQSVLAQDSSTTEDTLSDASLTATSAAALSTEDSSSSPASRSSATPNSSESSTSASSSSSVVSTSSITSSATTSESLPTLTNTAATIPSYPAASVPPTNDAPFMHRSSAPDGTVFIAVGAILGTFALAVLLWRGIVACMLHRSVERAARAQALSNDKAAYPIAPAAPFYKYTDHESSSPSLVGRNPDGVAGSASGRGVRRTNRGPIPSGTPSMTNLFYSPTAAPSAGLNTNRESRFLPAGFYASSNSPAPPVGIAQSSSAGQSIGLANLHPDARNYSRSNLVPEPSPENSPHFAPQRRNMSSSTLNLNRPSSARTPSAYLDDLLDENPHLFPPQQGQSQSPHQGNASPSQNRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0H6</accession>
    <name>A0ABR3Z0H6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Multiple RNA-binding domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MRD1</name>
        <name evidence="9" type="ORF">Cpir12675_003826</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000097">
        <property type="protein sequence ID" value="KAL1894091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051945">
        <property type="entry name" value="RRM_MRD1_RNA_proc_ribogen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN 14B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039:SF5">
        <property type="entry name" value="RNA-BINDING PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="11"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="327"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="509"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="633"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="738"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="175"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="292"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="810"/>
            <end position="837"/>
        </location>
    </feature>
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        <location>
            <begin position="200"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="860" mass="94846" checksum="D08842708C0E2E69" modified="2025-10-08" version="1">MSNPPNSVDSSRIFVRGLPPNITESDLRKHFSSNSSDVTDVKIIPQRRIGYVGFKTPEDALSSVRYFNRSYMRMSKLGVELAKPINDPSLKRRINRATNTTNTESNTLAASKAHDFVLGTSEAKKRKRVEAVDPTASDSKLREFISVMQSSKGGLETPDFGVDIETKATKQLLREDASDDEYEKIPSRPPKRQATEPQPVRQTAAVSIQTTSNASGEVKGSGEGMEVDAETKASVPLSAEATQAINDDDWLRSRTNRMLDLVDVEDIKPLAPSKDVTEPNADHSEAVPSMETTVVADPSPQECTAKPAREKPATEQDTDEATIRQTCRIFVRNLSYETKEENLREYFEKFGAVEEVHIPTTAAGKSKGFALIRFTDPEVAVAAFQRSDGVSFQGRLIHILPAAPKREGEIDEFALAKLPLKQQALIRKRAEAASNTFNWNSLYMNQDAVVSSMAQRLGVSKAELLDPTSSDAAVKKAIAETTVIQETKAYFMANGVNIDAFKQQKRGDTAILVKNFSFNTTIEELRNMFAEHGTVIKVLMPPSGTIAIVQMASPAHAKAAFARLAYRRVNESVLFLEKAPVNLLVNDDNATAAATTMEPTQGITKLGVQKLSVTQLLTEASEEAEESAQANTTSLFVGNLSFATNTEGLEITFRSQDGFVSARVKTKQDPKKPGKVLSMGFGFVEFKTKEQAQAALKALEGYNLDGHSLALKASHRGLDAAEERRRDDKAKKLHGQRTKIVIKNLPFEASKKDIRNLFSTYGQLRSIRLPKKFNHTSRGFAFADFVTAREAENALNALRDTHLLGRKLVLDFAEADAVDAEEEIEKMQRKVGSQVNKVKLQQLTNRDRTRVTIGDEGQDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0Q4</accession>
    <name>A0ABR3Z0Q4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type E3 ubiquitin transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003828</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000097">
        <property type="protein sequence ID" value="KAL1894093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="189"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="341"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="199"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="362"/>
        </location>
    </feature>
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        <location>
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            <end position="426"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="431"/>
            <end position="452"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="488"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="512"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="561"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="631"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="649"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="738" mass="80500" checksum="C7CF0A7B2B8F739A" modified="2025-10-08" version="1">MAPPLKVPDTGLVLWDSSDPSTNPKLPIQAFTLTLDKLALEDMIRCVQNGDEISLSLGKLPTLNYSSTSYKIPKSETSNSHDLFFTQPFESLRKAHRVPVVSDLYTKLPKAQPKKRTTTKSEPLSPISARQRESIAPASNKSPNLNSDLEILQNSMARHEAARGNTLVLGGVPPTDIRGSKNKSQLLRAAESLNSQTDSSSGSIKSASPGVENSAHAKTQNILERNKLQRVMVVHELAVRDQATEYLREKWTGKTEDFDAALHKAAEFDSTSKTWSLAKNYWKELDVWNYDYDSKQERQEAINNAISKYDRMRLSPNQDEWQRLLPAEERGKGRCLSRIQANLMKGPMSSVKTSEDKSEAMSRSKSNPLPKPTSKKTEKEKRLPATSSAKKATVPKAPKVKASATSTATPGASSTPSSVTAAANAPKKNYPLSSEFVTSDMSDSESHASVTAASLDEPRTTSNARKPSPTASSSKPTTRDSPTKPRAAKSGASSSKLAGSPTKSLSSAKIASKVVPTKTTVVKSTKTATSKRHREDEDEDDSSSSGTPLSKRHKVKAGNGATNTTSSALASLASSKNRSSETLRFSAISSSNGIKKTGSPLARNSPAPVSEPSETQARPRVAEKSAAVKRRPIETERDAPKPSKTSSVKNKETAKELATETKDGDGRKAKRPHAPPEELINKAARFKLNYERYAKLHAQIVNTENPRKDQVDYLTDLREKLKDMKSTIYYEHLLSYNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0X8</accession>
    <name>A0ABR3Z0X8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transcription factor mbp1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">MBP1</name>
        <name evidence="10" type="ORF">Cpir12675_003740</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000094">
        <property type="protein sequence ID" value="KAL1894263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.260.10">
        <property type="entry name" value="Transcription regulator HTH, APSES-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036887">
        <property type="entry name" value="HTH_APSES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA/APSES_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051642">
        <property type="entry name" value="SWI6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003163">
        <property type="entry name" value="Tscrpt_reg_HTH_APSES-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828">
        <property type="entry name" value="ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828:SF15">
        <property type="entry name" value="TRANSCRIPTION FACTOR MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01252">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54616">
        <property type="entry name" value="DNA-binding domain of Mlu1-box binding protein MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51299">
        <property type="entry name" value="HTH_APSES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0183">Conidiation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0749">Sporulation</keyword>
    <feature type="domain" description="HTH APSES-type" evidence="9">
        <location>
            <begin position="9"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="261"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="383"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="111"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="428"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="677"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="954"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="740"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="428"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="439"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="682"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="696"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="997"/>
            <end position="1010"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1894263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1021" mass="114572" checksum="AA1F0D2E868547E0" modified="2025-10-08" version="1">MAAKSYDGIYSATYSGIPVFEFLYGPELKESVMRRQMDNWINATHILKAAGFDKPSRTRILEREVQKDTHEKIQGGYGKYQGTWIPLENGKMLAIRNNTYEKLAPIFEYVGGDEPPPPAPRHTSKPKQPKRPAGPKWKATAPAATPPVVTPIVPSPIIAPPHEVVIDTMDMIREDDIPDTTTVVSVPFAGDDERIEPSQPGTGHRKRKRDENLDFIRQQHAVYGDELLDYFLLSRDEKTGKMARRPDPPPNFQADHTIDTDENTALHWACAMGDIEVIKELKRLGASLDSRNSRGETPFMRSVTFTNCFERDTFPAVMKELWETVNLRDITGATVIHHAATLRNDRVTGQSCSRYYLDHILNKLQETHDPAFVQSLVDAQDNDGNTAIHLAAKRNARKCVRSLIGRNASTEIPNVEGITGEEMIKELNSRTKDKERVPQRSSSPFGPDSQNPWLAMDRSNKKLGATYQSNAAKTVHSSITPLIFEKLQSMAHNFEDEWSEKDQAEKEARQILVNTQTETSMVNQEIQTLESQLEPDAVAAKVMDEATRARHELLELVRHRNGTQVQATVDQELKRMGNNEEITADDSIESKQELARSLSQAIKEEAQAEADYVDALSMVGTGEKIEKYRRLLRNCLDAQDAGVLDENIDDLIEMMEEDEQMIGPGMVVQEGGEQMDSAGALSAGSSKIGSVSSEPESPPTSHPRAPVFPPGSQPRWCRPLKRRKFSRRHPGGLRLTGEMGRKLRQAVAQARVERDREQQESRVREAREREIRARLEYIRIRRALAASGLRGDNPQVRSLNPLISASASTSVLPHQSQLPENLPLPLPQAMPPLLPNPTTSITTSQEMEPFESPADRMPDLSPMFPIIPAAYPRQAEAPMPESSFRRFSGPLQSQFPGLPRPGPFISPRSSHFLLRSSDVLQGDPMSMPTHFANQPHLAIDPELTHIRRNEPMNACSRWPTRPETPHWNNKENSHTFSSQRSACDAPPEAGNDHTDEFQDDLFPDILDETPEAWKWPLGKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z120</accession>
    <name>A0ABR3Z120_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PH-response regulator protein palA/rim20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RIM20</name>
        <name evidence="3" type="ORF">Cpir12675_003867</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the palA/RIM20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000099">
        <property type="protein sequence ID" value="KAL1893891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09241">
        <property type="entry name" value="BRO1_ScRim20-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.560">
        <property type="entry name" value="alix/aip1 in complex with the ypdl late domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.50">
        <property type="entry name" value="alix/aip1 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.280">
        <property type="entry name" value="alix/aip1 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025304">
        <property type="entry name" value="ALIX_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004328">
        <property type="entry name" value="BRO1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038499">
        <property type="entry name" value="BRO1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23030">
        <property type="entry name" value="PCD6 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23030:SF39">
        <property type="entry name" value="PROGRAMMED CELL DEATH 6-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13949">
        <property type="entry name" value="ALIX_LYPXL_bnd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03097">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01041">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51180">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRO1" evidence="2">
        <location>
            <begin position="1"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="738" mass="83607" checksum="906F46AABB41060C" modified="2025-10-08" version="1">MTSNLSSPNALIVPFRVGATASYSDAICQYINTQYDQHPDMFRNDLQAIDTLRREAVTVREPHVSGITKLQAYAAQIVWIGGKFPIDIGVNFPWYPAFGCNSDRPVVRNNLKYELLNVLYNLAALYCHLADSTSRGTPEGLKTAASYFSQAAGVLAHMQTEILPGLRMSDPPEDMDDATLEALTQLCLAEAQECFWQKAVTDGYKDAIISKLAIRVSDLYGEAASASMKSNAISSQWIHHMSAKQHHFAAAAQYRMACDCLEKRRYGEEVARLKEALACVNDGLRETKSGYVSKTVTRDLSGLKGRIDEDLKRAEKDNDIIYLQPVPTRMELKPLDRVNMATLKCPREVSSPCNFLGEDSEFGPPLFSKLVPFAVHLAVSIYEGRRDRLVNNDIVQPLDRLSEALNATLDSLGLPGSLQALEKPLGLPPSLIQRAEEVRQANALHRVENSFRDIDKLVAADLKTFEEGKQILMREEEEDKRMRNTYRDMWTRPGSREDEQGKKLWTQMGEIDNYFKISLPSDKLVRSKYAMIKPQLQLLSGSDRALLDYVPSSRRTDVPEGLRTVLARLRSTYNDVQRLQSRRRKKIDMIREKARSDNVRSAISREATRLERAYPGVSLDAASFDEWLESRLDTMYEAELAALAADEDEQNHVLGELSRVHREFESQKRVVGDRGGREREEVLQKLNMAYDKYKELLENAEDGRKFYNDLSKIVGARFRDCAKAWANNRRLDAQSLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z157</accession>
    <name>A0ABR3Z157_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytochrome c oxidase-assembly factor COX23, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">COX23</name>
        <name evidence="9" type="ORF">Cpir12675_003754</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the assembly of cytochrome c oxidase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the COX23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000094">
        <property type="protein sequence ID" value="KAL1894273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010625">
        <property type="entry name" value="CHCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051040">
        <property type="entry name" value="COX23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009069">
        <property type="entry name" value="Cys_alpha_HP_mot_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46811">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46811:SF1">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06747">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47072">
        <property type="entry name" value="Cysteine alpha-hairpin motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHCH" evidence="8">
        <location>
            <begin position="39"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00041104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF06747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="83" mass="9729" checksum="A2E486920E059329" modified="2025-10-08" version="1">MSSQPSNDKNPTASSEPLVSEEKRQQFRAKDMSKYFDPCQEAADRSIRCLHRNPNDKSLCSDYFQAYRDCKKAWLSQKSSKWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1J0</accession>
    <name>A0ABR3Z1J0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cupin type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_004156</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the germin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000112">
        <property type="protein sequence ID" value="KAL1893374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02241">
        <property type="entry name" value="cupin_OxOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006045">
        <property type="entry name" value="Cupin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001929">
        <property type="entry name" value="Germin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019780">
        <property type="entry name" value="Germin_Mn-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31238">
        <property type="entry name" value="GERMIN-LIKE PROTEIN SUBFAMILY 3 MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00190">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00835">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00725">
        <property type="entry name" value="GERMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045871607" description="Cupin type-1 domain-containing protein" evidence="6">
        <location>
            <begin position="21"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="7">
        <location>
            <begin position="85"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="265" mass="28103" checksum="24E69FD87E66ECF6" modified="2025-10-08" version="1">MIFTAAFLSAVLAFSGQAAAVPHQARYASSNSAHSMHTSATASTASPSPTATMPANQLSLVQQLMLAPLAADRFALLPDNKDFVINLEPEPVPTGKGGNLVAANRKTFPALVGAGAGMAVGVIKPCGINTFHVHPRSTELQILIKGSLVVEMTPENGVLDPATGKRRVIRNTLSEFDMTPFYQGSVHHQFNPNCTDAVFVASFASEDFGTGQVVDEVFSMDKNAIIDTFGATLSGDDVERIKAGLPESIVQGVEVCMQKCYNHRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1J7</accession>
    <name>A0ABR3Z1J7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="3">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GTP cyclohydrolase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GCH1</name>
        <name evidence="10" type="ORF">Cpir12675_003856</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000098">
        <property type="protein sequence ID" value="KAL1894072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00642">
        <property type="entry name" value="GTP_cyclohydro1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00223">
        <property type="entry name" value="FolE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018234">
        <property type="entry name" value="GTP_CycHdrlase_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00063">
        <property type="entry name" value="folE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006825">
        <property type="entry name" value="PRK09347.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006826">
        <property type="entry name" value="PRK09347.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109:SF7">
        <property type="entry name" value="GTP CYCLOHYDROLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="GTP CYCLOHYDROLASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00859">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00860">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP cyclohydrolase I" evidence="9">
        <location>
            <begin position="143"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="36"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="51"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1894072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="323" mass="35669" checksum="AA51767EB24C00B9" modified="2025-10-08" version="1">MAAPQVKSAASRNSSPIANGMHHKLKTITENGAVGSSSSSDESGSTASKRGGSKQPKKEKSSRKRKATEKMDFDGDEDKIANTQNGVVEMAKRTKYKTRNENVNGSTNDDNDGSAGLALSNSLQTPRNDKDEAATQARIKKMSEAMRTILECIGEDPDRSGLLDTPERYAKAMMFFTKGYQETVPNIIKQAIFNEGHNEMVIVKDIEVFSMCEHHLVPFTGKMHIGYIPREKVVGISKLPRIAEMFSRRLQIQERLTREVATAIMEALNPQGVAVVMESAHLCMVMRGVEKTTTSTITSCVLGCFERKSKTRNEFMSLIGLNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1Y9</accession>
    <name>A0ABR3Z1Y9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">THIF-type NAD/FAD binding fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003612</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000088">
        <property type="protein sequence ID" value="KAL1894623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00755">
        <property type="entry name" value="YgdL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43267">
        <property type="entry name" value="TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43267:SF2">
        <property type="entry name" value="TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="3">
        <location>
            <begin position="107"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="516" mass="56515" checksum="B1368C02FF871708" modified="2025-10-08" version="1">MTTIASTLSDWLNSPKFQLAATAIVSGAAVAGIILGAQALEREERLIQLKQSIPPPSSASQPAEPLSSSVPNPLPHKTKEDIRNEALAARAIAGEFDEELILEQLARNRVFLGDEGLEKLRNSFIVVVGLGGVGSHCCASLARSGVAKIRLIDFDQVTLSSLNRHAVATLADVGMAKVQAMRRRLMAIAPWVDFDMCGEKFDGDSAERLLGPWRDSGVKPDYVIDAIDNIDTKVTLLKFCHSNNIPVISSAGSGCKSDPTRIMVGDISASTDDRLSRSTRRKLKLVGVGSGIPMVFSTEKAGEGKAELLPLNQEEFEKGKVEELGVLPNFRLRILPVLGTMPAIFGYTIANHVILSIAGYPTPYLPTKMREKMYDTSLAAIQAFEEKLARHVSGNTANIAVGLKVPITTVDIMFLIEEVYKGRSVVTGIPTKLVLIRWEKPTEAEMLKYIGEGKEQQKSTNLKMSHVVCMTKEEATHHLKKVLMEGKPHTEVYPADVIELVTKRREETALWEKEIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2E9</accession>
    <name>A0ABR3Z2E9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_003499</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000084">
        <property type="protein sequence ID" value="KAL1894804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_6G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180:SF63">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G03520)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="270"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1894804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="281" mass="29576" checksum="60ACF199060A6D13" modified="2025-10-08" version="1">MSGRLAGKNAVITGAAGGIGLETSILFAQEGANVLMADISGPALEKAKAKVLEIVPSAGKVETQICDVSKEAQVQALCEALDSWGGLDIIFNNAGIMHAKDDDAVNTPEAIWDLTQNINVKGVWFGSKHAVLALRRNNKTKGSVINTASVVALVGAATPQLAYTASKGAVLALTRELAIVHAREGYRFNSLCPAPLNTPLLQDWLGDDEAKRLRRTVHFPTGRFGEAIEQAKAVLFLASDESSFVNGHDMVVDGGMTKAYVTPEGPSTPAPTNNALKSSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2J1</accession>
    <name>A0ABR3Z2J1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CIT1</name>
        <name evidence="4" type="ORF">Cpir12675_003480</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the citrate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000083">
        <property type="protein sequence ID" value="KAL1894835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036440">
        <property type="term" value="F:citrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06105">
        <property type="entry name" value="ScCit1-2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="entry name" value="Citrate Synthase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="entry name" value="Cytochrome P450-Terp, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010109">
        <property type="entry name" value="Citrate_synthase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01793">
        <property type="entry name" value="cit_synth_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007128">
        <property type="entry name" value="PRK09569.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739">
        <property type="entry name" value="CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739:SF8">
        <property type="entry name" value="CITRATE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="470" mass="51994" checksum="98838A4E4B7AA447" modified="2025-10-08" version="1">MASVARLSSSALRTSVRGTAFRNSSFAATRFYSAKAQTLKERFAELLPEKVDQIKTLRKEHGSKVVGEVTLDQVYGGARGIKCLVWEGSVLDSEEGIRFRGKTIPECQELLPKAPGGKEPLPEGLFWLLLTGEVPTEQQVRDLSADWASRAEIPKFVEDLIDHCPNDLHPMAQFTIAVAALEQNSAFAKAYAKGVHKKEYWSYTYEDSMDLIAKLPTIASRIYQNVFKGGKVAEVQKDKDYAWNFANQLGFSSNESFIELLRLYLTIHTDHEGGNVSAHTTHLVGSALSSPFLSVSAGLNGLAGPLHGLANQEVLLWLTEMKKAVGDDLSDENITKYLWSTLNSGRVVPGYGHAVLRKTDPRYTAQRTFAQKHLPEDPMFKLVSQVYKIAPGVLTEHGKTKNPFPNVDAHSGVLLQHYGLTEASYYTVLFGVSRAIGVLPQLIIDRAVGAPIERPKSYSTDMWSKIVQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2J4</accession>
    <name>A0ABR3Z2J4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Dolichyl-phosphate-mannose--protein mannosyltransferase</fullName>
            <ecNumber evidence="4 14">2.4.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">PMT2</name>
        <name evidence="17" type="ORF">Cpir12675_003471</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17377"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:13546"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137321"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 14">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53396"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13547"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137323"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Endoplasmic reticulum membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the glycosyltransferase 39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.109" evidence="4 14"/>
    <dbReference type="EMBL" id="JAWDJO010000083">
        <property type="protein sequence ID" value="KAL1894826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004169">
        <property type="term" value="F:dolichyl-phosphate-mannose-protein mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23284">
        <property type="entry name" value="beta-trefoil_MIR_PMT2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003342">
        <property type="entry name" value="ArnT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036300">
        <property type="entry name" value="MIR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016093">
        <property type="entry name" value="MIR_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027005">
        <property type="entry name" value="PMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032421">
        <property type="entry name" value="PMT_4TMC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050">
        <property type="entry name" value="DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050:SF46">
        <property type="entry name" value="PROTEIN O-MANNOSYL-TRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02815">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02366">
        <property type="entry name" value="PMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16192">
        <property type="entry name" value="PMT_4TMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00472">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82109">
        <property type="entry name" value="MIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50919">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 14 17" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="226"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="280"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="600"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="642"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="668"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="700"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="16">
        <location>
            <begin position="334"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="16">
        <location>
            <begin position="400"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="16">
        <location>
            <begin position="464"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00045085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1894826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="741" mass="84256" checksum="3F59AD499790C2DA" modified="2025-10-08" version="1">MASQKAAVASGADLAEGLRRRTAQSGYQTETPSAPIVDDKKKLAPKKSGLDILFQWEWIWGPTILFALACFTRLYKIGLSDIVTWDEAHFGKFGSYYIKNEYYFDVHPPLGKMLVGLSGVLAGYNGTFEFKSGEKYPEELNYTFMRAFNAAFGIVCVPMAYWTARELHFKRPTVWLVALMVLCENSYTTISRFILLDSMLLCGTVATVLCWAKFHNQRHRSFEPEWFLWLFLTGVSIGCVCSVKLVGLFVTSMVGLYTVEDLWNKFGNHRLPAHVLGAHLSARIIGLIIVPFLIYLLSFALHFAILSNSGPGDAQMSSLFQANLKGTSVGKGSPLELAYGSRVTIKNMGYGGGLLHSHIQTYPEGSKQQQVTCYHHKDTNNDWLIYPNRGDVDYSEDEEPRFISDNSVIRLIHAQTGRNLHSHDIAAPITKADKEVSSYGNITVGDAKDHWQIEVVSDVASRDRSKVRTLTTAFRLRHPIMGCYLRAGTVNLPQWGFKQIEVTCAKTNNPKDTYTHWNVEAHTNDKLPPSDPAVYTSPFFHDFIHLNVAMMTSNNALVPDPDKQDDLASQWWEWPILHVGLRMCSWDDKTVKYFLLGNPLIYWGSTAALGVVGLVVAWYLIRWQRGYRELGQEDIDKIHYSGIYPIIGWVLHYLPFVVMARVTYVHHYYPALYFAILSFGFVIDWLFASQNKVIKTLVFGTLYIATIGLYIYFIPFCWGMTGPNRDYNYLRWFSRWKMTEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2R3</accession>
    <name>A0ABR3Z2R3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Helicase required for RNAi-mediated heterochromatin assembly 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_003649</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000090">
        <property type="protein sequence ID" value="KAL1894472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057373">
        <property type="entry name" value="ZNFX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF341">
        <property type="entry name" value="NFX1-TYPE ZINC FINGER-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25396">
        <property type="entry name" value="ZNFX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ZNFX1" evidence="5">
        <location>
            <begin position="83"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="3">
        <location>
            <begin position="275"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="3">
        <location>
            <begin position="566"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="4">
        <location>
            <begin position="665"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1033"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1033"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1056"/>
            <end position="1065"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1894472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1077" mass="121599" checksum="D8D5F86C6546D9EE" modified="2025-10-08" version="1">MPKPDSDTSDTPSWWRSEIPDREEIISDYPILPLENDISKLPESRESHAAIHYSLLRHEATELLRRSISEYKITPDMMDSMETKVFLEGLVANIHGISYRISFSIEKSPIKIDWETSKRLTAGSLVAISPLSDNFSSKVVVAVVTKRILEGGLLPGDGEHAFTAPRIDVSWRDEEDTKFMLDPDQELVMIQAGSSGLYEAVRHVMEGLKRWSKEPTKFDKFFISGNKHPHSAPLFNGDKSIINIESMVPPNMDFPDRNVDLSSPLPQEFGVASGLDPTQLLAFHMMLAKEVSIVQGPPGTGKTFISVSALKVILENLPRGDTVLVTAQTNRALDQILMSCLNLGARVARLGSRSREAEISERTVHALYMNMPNKPNSFGLHAQEKKRMSTVTALQHAIEKTYPTELLTAQSLIEAGLITSEQSETSFSLDWSEFPGLESFESSANPLVGWLEGKFVETSTRLDIPPEVEEDTNDDLDVPDPVEDVFAPQDQDDRKEVFIPVKFKYSVQTDKNVIESEALWRNIEFAAKKHQDLYKIAVPRRPWLYKLWLKKLAEAGRNSVWNLIGEINMLSRACNRSRQHRNAAVVRASKSNVLGCTTTGLTKFRELIEHVRPRVMLIEEAAETREANIIAAPLSSVEQMILVGDHMQLAPHAEVRCLTQSPYNLNVSLFERLISIGIPYVMLRVQRRMAPMIRSLINPFYKDLEDHEIVRCRTQRPLVPGMGGLETFWFHHEWPERLTGLKSRINITEAKMLVGLFRHLVQNGTPPDRITVLTFYKGQVPIIRMLLEEDSGINALTSGPFHIFTVDGFQGEENDVILLSQVRSPLECGSWSIGFLDDFRRTVVALSRARRGLYIFGNFENFLYAKKAETAWLRTLEILMEQNRQGPALELICEKHGIKTCVTHPDDLARLDGGCEEKCKEVLVCGHECPKLCHSYHHDKILCEALCDRPMSCGHACTKTCIDECKCDECNGTTPRSLDAVDTTDFMNMSLDERLEMIIMSREKQEYEVNDQESISDINVESDSESYSNNLMEDLTLNKSSTPEKTAKRNRKKGNNSKGKNTGNASEWSKFGVLIEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3I2</accession>
    <name>A0ABR3Z3I2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_003848</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000098">
        <property type="protein sequence ID" value="KAL1894064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF50">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="106"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="182"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="848"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="948"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="880"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="962"/>
            <end position="986"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1894064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1054" mass="116745" checksum="70601A1A6E37D175" modified="2025-10-08" version="1">MSHTSHPHPTAPSDAGSSVAGLSPAPDSAPNIDSIPPPSTSSSTPAPAPASTPAPPSAYPSADAPATANVAPPAASSRPGVTILAPGEEPPASLLASLSSELNPRSCITCRRRKVRCDKFMPCSNCRRNQIQCVFPAPGRAPRRPRLKDPNAPINNLSEREAQLLKRLRKLESVVEELSGQLDAENLSRQSVGGSPDTAPGPNSPNQGLASPVHGTPGSVSSARDESTTRNAPRRSRVEDAAEGSGKDSTITNKFGRLVLSDKAKGQYVANAFWSKLTQQIDEIRHDAHSLSEDSEYSDGGTPESFYNSIASGTDNHDGFFFGYRSSTVDLSKLHPRASDIPFLWKIYCTNVEPVVKVVHVPTWSVVINQVQMGNTTISIQKEAMLFAFYFAAITSLEDEEIETRFNASKERLLNQYRFAFEQSLAKAEFLTVPDLTIINALALFLTVVRTSDDSRYCWTMAAVAVRLAEALGLQRDGTNFNLTPYEVEMRRRIWWTICAFDLRASEESGTDSSALVFNCDTKMPANINDVDFGPESSEIVSCQGTTDISLVLVRHEITKLCRRMIAMSDRAPVLGQPNALQSIREREETLVEMHRHIETTYLQCPEMETNSCLILAAMIVRVVVAKMSLVIYQPLLLSGSVNNKTKGPISKDSKHSEYNDRVYMAAVEIIECNVKLHTQERFRQWRWLFATYTQWHAIAFVLMEVSHRPWSANMERGWDIVTRALNQKEVQEFAKKPNHMTVWLPLRKLIAKASRNRNAEIERLRANPMEVRKLDMEDRMISSQRYISLSKDLHYELAELRERWLTLVGANSGSMIATPPMSNSRTPPIALTHSVLQSMQQAYASNDQPVAGPMAPKQSRDPPSDSLNSIRQPPPPPQQQQQQQQQQQPIGLNIMMNQPMSTMVLWNLIDQNAQPGMMGNMQMAPHDSPMPILPGNQAMHRAAAPPVVPSHMQPHQHQDGQRQSPHLHSAPPNDQQGFGTWEWSNNYPLPATAPNVAPTPGVPTSGVNVNGMFISDDHGMEVDEEFSWESWEETIRNLNAPQGLFNAQPPGLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5L1</accession>
    <name>A0ABR3Z5L1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Vacuolar protein sorting-associated protein 29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">vps29</name>
        <name evidence="7" type="ORF">Cpir12675_003256</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the VPS29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000074">
        <property type="protein sequence ID" value="KAL1895350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07394">
        <property type="entry name" value="MPP_Vps29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000979">
        <property type="entry name" value="Phosphodiesterase_MJ0936/Vps29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028661">
        <property type="entry name" value="Vps29"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00040">
        <property type="entry name" value="yfcE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11124">
        <property type="entry name" value="VACUOLAR SORTING PROTEIN VPS29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="6">
        <location>
            <begin position="4"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="201" mass="22174" checksum="C35CAD335C96B889" modified="2025-10-08" version="1">MAFLILVIGDMHIPDRAFDIPAKFKKLLAPGKISQTLCLGNLTDKHTYEYLRAISPDLKIVKGRFDVEATSLPLTQVVTHGSLRIGFLEGFTLVSNEPDLLLAEANKMDVDVLCWGGTHRFDAFEYMGKFFVNPGSATGAFLPSWTNDNDEPVPSFCLMDVQGISLTLYVYQLRKGEDGNEAVVVEKVTYTKPVEPTAPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5M6</accession>
    <name>A0ABR3Z5M6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Heavy metal tolerance protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_003380</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000079">
        <property type="protein sequence ID" value="KAL1895108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18583">
        <property type="entry name" value="ABC_6TM_HMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF503">
        <property type="entry name" value="MITOCHONDRIAL POTASSIUM CHANNEL ATP-BINDING SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="461"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="486"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="573"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="347"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="664"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="224"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="952"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="229"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="253"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="288"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="959"/>
            <end position="997"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1895108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="997" mass="111410" checksum="F0A84147E192EFF6" modified="2025-10-08" version="1">MSLAGRPFEASGVWNNVTGWLPIVKFSADDVLVTLRYVYPCSVYAYFMLSSITSVVFLHSLKASIHKKPDSFRTPWLIRFMHFCSFSYLAQLLTIFFRSFVASKWLGKDDEVVSTAACMILYAIQSLCISDNQFPVWYPYYGSWSIGLICEPCMILVWAYTSRPFELGSFYDLFTLALCGLRTLFYFFAIVVYMAKKQLKPSNVVVDEEQQLCPTNEVAIDAEQQPLLSNSASNSSDSGRSAAKNTLDRPLSSYGSTIQAGSTDSFVTGPRKDDNDQGNGNESHGNDDTDNMDGEGDENLDSDKKSEQELQKRLLEEGNWLSYLKRYKVLLPYIWPMRNYKLQFFAVLVAICSLTENVLNLLLPRQLGLIMDSLTRGVDSIVWSQLTIYALLRALGSDCGISFIREWLYFPIENYSKENLNRAAFDHVLKLSADFHDSKSTSETMMAVRGGESFSSLIETVMLNGVGMIIDLFLAIIYLTSTFGPYEGLITTTTGTLYLFLSASLLIESRQAKRSYVMALYKEGKNLHDGIDGWQTVASFNQTRYERDRYSKSVLELIGHMKRYTFHWFGTRALQSLSLLVGLLAGCCLAIVRIKNGQATPGQFAMLLMYWNQLSAPLMNLSYISKHISSMMIDAERVIDLLNTKITVTNQPGARPLRLTRGDVEFNGVTFGYSDKKNAVTGLSFFVHGGQSVAFVGVSGAGKSTILKLISRFYDPKEGSILIDNQNTKDVDIYSLRDHIGLVPQTPVLFNDTIMNNIRYACMSASDEEVHEACKAACIHDKIMGFPQRYETKVGERGVKLSGGELQRVAIARAILKRPDIVLLDEATSAVDTDTEQKIQASLNNLTENRTTFIVAHRLSTIMNADRIIVIDDGKILEMGDHESLLKVCGKYYSLWSKQVFLKPKKEEEEDKGKDIFVNDLSEDTMAAEQVKATSLLHAQVSKLEDECVKDGVGHTAGERQQAQVTASDIPTSVATNAGSRSTKSTIDTPMQRLSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z673</accession>
    <name>A0ABR3Z673_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">HUL5</name>
        <name evidence="8" type="ORF">Cpir12675_003090</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000068">
        <property type="protein sequence ID" value="KAL1895757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044611">
        <property type="entry name" value="E3A/B/C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700:SF2">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="7">
        <location>
            <begin position="801"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="343"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="351"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="5">
        <location>
            <position position="1138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1170" mass="132970" checksum="DBAA5CAB8B529EDC" modified="2025-10-08" version="1">MIPSFSGNSRRTRNVNLSGRGGNSAFSVWAPSSGFGASDTVNKAEEKRKRRQLEKKKSEAAQTVQKVWRGHKTRSSLRRSRLLELDKLYSPAPELDPRRRLHSAVPLISATFRPTSIDCQRMLAVVRDIRKVGPEALPSLASGVKLRLFSDKIIDALRMLLPFNVSAINIRDFDDLLHALFLVASCAGFSLRPQLPKYYGILTDIRDCLSLTQETRDSWVAAVRAPLELSCSNMVDKDYVVSVYKAFSFSLLMHESTDVARAIMKSLAGMINISVLSSVIVDEFSKNKGVSKHNRKALWLVAHLILLGFEAGHDTTYGTFMDALLTLISMIPKQLIHLASRKDSEPLDQMSDNETESEDEENDAKTTVEKIKIPPYVKEQLESLTTQSAIETLVKSFNLETLKTPQEVALATSTIAGYMLCLFKCFPKQRDEISLRLFLANINTPKGAIPLLQHFLSVVLKTTIYRRVISSDLEPLDALKQYLDSPLNRNVRDTEWRIILLTLDLYSFVLRLTDDDDFFARLVIPDELLTLETPRIQQCNLPMVEISSLSRFLCEMSFPLYNNKAELKASSNIQSPILATVSPQAGAFWSSGETHGIKAQKEQQSVSSLIKLDLPRLKVIITSALKMIYDRNSRRRFLPEGHWLMTTKFNMSGFVTEVVIEHERQSAAEDEALEDTEEAEAESFNSRHYLRSSLGQNYQIRREAQIRRVHRARMTAIIGPRLEVLRYMPFVIPFETRVELMRKFVQMDRMKMRKGRIDHENLRAALNNRNGGFLRGRDVRIKRQELFESAFDELWKVGAGLKNPLHITFVDHFGATEAGIDGGGVTKEFLISLTSEAFGGSRLFTTNSQNQYYPDPSQYDWYYQLSRKASTTEEKQECFVKMRGILNRYEFLGRILGKCIYEGILVDASFAPFFLLKWIMGISGATGYKGNVNDLRDLDEQTYQGLVMLKNARDASEMELDFTVDDKAEIPGTAPIYITRNLIPNGDQVMVTNENRLLYTSYFSRHRLIVQSQQISAAFLRGLWDIIAPSWISMFNQWELQRLVGGDSAPVNLDDWRANTCYSGIYVIGGDGEEHPVIKWFWEVMYEFDEGQRRQVLQYATSVPRAPLLGFSQLNPRFAIRDSRSSSDVERLPSASTCMNLLKLPPYKSKDVMREKLLYAIQSGAGFELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6W8</accession>
    <name>A0ABR3Z6W8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003048</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000066">
        <property type="protein sequence ID" value="KAL1895826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="337" mass="37504" checksum="555E438540482374" modified="2025-10-08" version="1">MPRTANRGTERRDIHPAYIQPAHSSSPSVEAEGTSEQDPASTIATSRTNSPIHNVPHPGLIALSTAAANSQSSLLGLLLKHVNEDLNAYTYDRDYCNYQLHNEANLTPEEARALRLRVMDANHKIRKCQQKSELIHFEAQTGINPSLVLGEKGAVQAFVPSEAPVVSPTIPEPIPLEDPGAESNIPPVTKRRRKSEWTNEDYNTFKVDESGDNDDSGAQVQRLGFWKCRLCTTQKYLRAGPGRQPSGPCKWPLKDVAKMIAHFTEMHHEHMPRERCIELGDALDKNRGPFEYWLRRSHSISTADGPLIEECVGVLRSGKLPPILRKLSRAAASFPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z762</accession>
    <name>A0ABR3Z762_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000058">
        <property type="protein sequence ID" value="KAL1896454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="128" mass="14418" checksum="0F4BE16D714A9058" modified="2025-10-08" version="1">MAQQIEKLTALLASTQTLAPSPPAPPLIPVASPPMGAPPMRTKINAPWSKWDGAPQTFPMFFIQLKVRARMDHEAGQKDDSISLNLLYSLPHVRQVAVQHKFSKGEERGYGWKDFIEYIRGRFMDQEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7C6</accession>
    <name>A0ABR3Z7C6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transaldolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002887</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000061">
        <property type="protein sequence ID" value="KAL1896240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="TRANSALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683:SF39">
        <property type="entry name" value="TRANSALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0704">Schiff base</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="360" mass="39602" checksum="7E748259EB0D89E9" modified="2025-10-08" version="1">MAATKKTMLQLLEEQVDVDVDWMDPEFIRSNDRTFHDMTSNQFIVDAQIGRPENRDLIVQAAQELGTGDWLAVYTRVAAKLCANNLPYLHGRVFLQTRPADAFDATATLLYARQIAAEFARLGVGCDRYAIKIPITGAGMAAAKALRADGVASLGTVLLNVDQAIAASQAGCYYVSPYFNEIKAHVDRAVWPELRDPAADHPMAPRVAQIYHVYRELYASSGTEQPRIKLASLISMAECMVPAELGCHSITVPMPLLAELAATPAAMEAVRVKPEHPYAAPAKGLSHRLEGLLKRDPLRESWDGVLPSFETDYLADGGKALDEAVGKDTEAKRRLNFALEFFDEAEKRSKEIVETVLKAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z873</accession>
    <name>A0ABR3Z873_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">SNF1</name>
        <name evidence="16" type="ORF">Cpir12675_002806</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000059">
        <property type="protein sequence ID" value="KAL1896402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd12122">
        <property type="entry name" value="AMPKA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14079">
        <property type="entry name" value="STKc_AMPK_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14334">
        <property type="entry name" value="UBA_SNF1_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.80">
        <property type="entry name" value="Kinase associated domain 1, KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032270">
        <property type="entry name" value="AMPK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028375">
        <property type="entry name" value="KA1/Ssp2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013896">
        <property type="entry name" value="SNF1_UBA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF110">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16579">
        <property type="entry name" value="AdenylateSensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08587">
        <property type="entry name" value="UBA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103243">
        <property type="entry name" value="KA1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="95"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="443"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="468"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="523"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="468"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="544"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1896402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="758" mass="83945" checksum="FBCA8F99B28631FD" modified="2025-10-08" version="1">MQHLAPPDVKGPAHGGFEDEELTISLSPSRRNSKRNLDPNDPSIVAGSAPGAASSVPMGPSTLPLPPPAVDPHAPGSSGVIHDPGSIVEQRIGAYKVIKTLGEGSFGKVKLAIHNSTGQKVALKIIPRKKLISRDMAGRVEREIEYLQLLRHRHIIKLYTVIKTSSEIIMVLEYAGGELFDYIVQHGRMREATARRFFQQMVCAVEYCHRHKIVHRDLKPENLLLDNDLDVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLVGRLPFDDDHIPSLFAKITRGAYSVPQWMPSGAAQLIKRMLVVNPVQRISVEEIRRDPWFMENLDPYLRLPAEEFFHTGIDPNKSINQSVSKTGVLNNEQKKLYNEVADRISKTMGYGRKDVEEALQAEEPSAIKDAYLIVRENKLMENQEAAAIAAMSSESQSQPGTPVCEKSHSADDAAVAAAAAAASQGAPSPSAPSIASVQSSTTGPRSYVSKVGILPSSIPAYHKTYVDKEKSGPVDAVAPSVIVDDPSGSRTDADKEETARRLKPHSRNTGRIDETNQRPQGLTPVNPPKKAKPVRWQFGIRSRNAPWEALLCIHKALAKLGAMYIPDENWEPMESGEDLPPSYREMDDGGQIQRDQYDPRKRYKLPADPWNIKVRWETEALRKPTQPLPAPSNVRRTSDGEAFEIVAMFLEIQIYEMDRGVYLVDFKCAGYETWDHYMLDQKDVTSPFPFLDMAARLIMQLAEAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z910</accession>
    <name>A0ABR3Z910_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cysteine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RIM13</name>
        <name evidence="7" type="ORF">Cpir12675_002494</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C2 family. PalB/RIM13 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000049">
        <property type="protein sequence ID" value="KAL1897173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00044">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.380">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022684">
        <property type="entry name" value="Calpain_cysteine_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022682">
        <property type="entry name" value="Calpain_domain_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022683">
        <property type="entry name" value="Calpain_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036213">
        <property type="entry name" value="Calpain_III_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051297">
        <property type="entry name" value="PalB/RIM13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46143">
        <property type="entry name" value="CALPAIN-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46143:SF1">
        <property type="entry name" value="CALPAIN-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01067">
        <property type="entry name" value="Calpain_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25435">
        <property type="entry name" value="PalB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00704">
        <property type="entry name" value="CALPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00720">
        <property type="entry name" value="calpain_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00230">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49758">
        <property type="entry name" value="Calpain large subunit, middle domain (domain III)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="6">
        <location>
            <begin position="117"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="356"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1897173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="842" mass="93854" checksum="EC00C1C24238A2A4" modified="2025-10-08" version="1">MSSCRQAQVHEGLASQCNGAKALQHATIAAELYLKAVSEAQSAAERNRLRLKCQEMLTLAEALKGVSSKDGPALSTAMSTRSTAVGSSSRQLSARERAILTHASNLHGCKHPPWDQAPDNSAFRKEPSGILFKDTTNFSLSAIQCENFDGWKRPMEIIRDKSGGDPQRRVSMVVNSNIDLAQDVTTDCSVVASLCSAVKNFKPGKDSLLNGMIYPFDKDSGVPAVSENGKYIFRFHFNGCPRQVVIDDRLPFSRSDKTLFVVDLQNPTSMWPALLEKAYLKVRGGYDFPGSNSCIDLWIMTGWIPEQVFLQKEDLNLDQIWNTLVSGFDSKTVIITLGTGRMSKSEEKALGLVAEHGYGVLQLDHVGNSRKLLVKNPWSTGPTWRCLQDTMSEINPREQQIRTRSFWVTFEDMVQNFESMYLNWNPALFKFRQDHHFMWSVAPVEDMSDTVYKNPQYQMVASEKTSAWILLARHHRDEELQLARERSSSRSDSSLGYMSIVVVEDGKRIFKLPVSGSKGGDFVDSHQTLTKITLDPGKKYTVVPLHDKLPLSSYSFTLSFFTMSPINVGTAPERRVYWQHKSSSWSRRTAGGNSSFPSYGINPQYQFTLKKATSLSLLLSSDAPNIPLHFDIVWTAPGERAQFPLPRRIVVADSQEYVRRSASADEVPVDAGTYNIVCSTFQPNQFTNFSLVVGSDEKIDLNIVPVTNAGKLPVSLPQLVFGEGTSRARIPIGSNHLSRTNAMMHLVHDPQRPSKSSSSFRLSVVYGYGLSEDHVAVTGGGEFEEIKVSLSTTDFDIEPQRIVDTGLWVVVDRIGGRFSTEIVQIELFSDRLLAIGTWEIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z956</accession>
    <name>A0ABR3Z956_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WD repeat-containing protein WRAP73</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002458</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000048">
        <property type="protein sequence ID" value="KAL1897201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052778">
        <property type="entry name" value="Centrosome-WD_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16220">
        <property type="entry name" value="WD REPEAT PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16220:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN WRAP73"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="528" mass="56709" checksum="EDD659FBF747F033" modified="2025-10-08" version="1">MFSSPIFKTSPFCVASPDGLLLAILQQARIVVREITTLQIVHEISIPNDAASSAFGLVWAPSSTKVLVAAGDKLLVYSALDSSFQATVKNPASSSAKPTHVQFGPTDSEVAVFSHFGLKLALVNLATSSVVEVTNPKFHQPPSVSRGISFRPGSHHLALLTRTNGKDSISIHLPGSRSVERAFHPDTVDAQGVLWASKGRWLIVWESAAHGHKMLMYTPDGHLFNTWAGPPDIGAEAQHFDLGAGVKHFHMDRLTTKAAVCDYTTTVTIMDLTIGSQMMRLAHPETVTPVDTLQVWLEQEQQPKNLPVFTRATQAFSPPERTTFTTAASSSDLASGCFLADFDCMSGLLATVTEAHRSTLWIWDLNSVDLRSVIMFHGIVSNVAWHPLVPELLLITCTTDSTAPSTVYVWDPLLGGPRPVASPAQLRKPTTKPGGTAGPKNRAAWISAQTELPLLLIHDGANGLVVAVGDAALDTAVSWGDNSHLSAKVLHGAAPAGPKVLDVAEMSFADEEGTVRVDDTFDFKKQKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9D9</accession>
    <name>A0ABR3Z9D9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000058">
        <property type="protein sequence ID" value="KAL1896443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="323" mass="35781" checksum="ECDBF675618A9C03" modified="2025-10-08" version="1">MSSPSASKDGKAPLPSPLSQLGGARDSSLHSSSPSSPQLKVSKGNRKNSLNRPNMLNVKSISQAHPRSLAQLPQNDLIWEWQYLNSQLLSQQGWAEKVVRRLASLQAQRGSGEAVNKRAVQRKISLLQNQVHTCSEQQNSLTPRINQLALEIRRRQLVLEEYNQRMYINAGYYQYPLPEWYPISLVPTHYGIPSVAAHVNAIAEGVMDVSMAAPQDEISRTNTPIVSTASWSACCQMPEETPSLESSMFSDPIIKQLAPSMDLRTPPSIECLYISSCPSSPQLMSRDKDGGSHFSPLSLHGPFSEKARRQSLCVLPSPRSFFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA85</accession>
    <name>A0ABR3ZA85_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA-splicing endonuclease subunit Sen15 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_002493</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEN15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000049">
        <property type="protein sequence ID" value="KAL1897172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042777">
        <property type="entry name" value="Sen15_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018593">
        <property type="entry name" value="tRNA-endonuc_su_Sen15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036167">
        <property type="entry name" value="tRNA_intron_Endo_cat-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28518">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28518:SF1">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09631">
        <property type="entry name" value="Sen15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53032">
        <property type="entry name" value="tRNA-intron endonuclease catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA-splicing endonuclease subunit Sen15" evidence="4">
        <location>
            <begin position="35"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1897172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="185" mass="20815" checksum="50A573BE80F01E6D" modified="2025-10-08" version="1">MSLNSSTTSSIMQTSSPSPGHVTSASPSTQELVNLVLHNLQNQHEWTGVKTHRLDHSSVNKCDGEFASLYKGSLPRPLISGLPPRRMYIHPDEQIAALEIEKQTGTRPTLGPEFEWVLPVHISEQWAIKDFTSMFAVIDALGDTRARKNWVRTFKQKRLMLAIVHNDSTVVYYLVHDGSVKPRQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA97</accession>
    <name>A0ABR3ZA97_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Mitochondrial carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_002316</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000044">
        <property type="protein sequence ID" value="KAL1897528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF26">
        <property type="entry name" value="CARRIER PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G07710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="202"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1897528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="530" mass="58112" checksum="2246208A1DCCEFD5" modified="2025-10-08" version="1">MKGPRDDVPLFMASISTPPISASLLEGLPNDGSLGLLPVLPDGPEASQKQKKRNAATAASAASVRALSAQAIAFYFRAPAKAFFRMRVDYLAFARRLHQAEAETLRNALHATRQQATGNASAMSGPLVRVWHHALVWMHGTTPGVLASAVRQQGWGIIPHQVVPPLAANVGVGAVLYTSYLHILGLLHEESGRGTKHVYPPPRPVHTFEAGFLAGALQSVVAAPLDAIQARYDHGDLMRSGDGRPQSMWSFSAQKIREIGLRGVFAGWGLSFIKDSLGSAVFFSMFEYVKAQGYYNFVSWYYGGLQDSIVADLALKRPVGGNLTSGEAATNNSRLHNGFTVIRPHYAIEPGFLLLAGISASFAQQIVVHPLTHIQLEHWDRLEDLDARAQEIRGLRARAEAVAMPTLRETATKTGSKPGSKMLAATATLEESSVPKAEKARASIKSPPRGLMLQANYRAYQETWRQCVGQARAEKKGILSWLYRGFWWNTIRQVPSTSAGLIIFELVRRKYGMDSEKVRIQHDDYEILLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAR5</accession>
    <name>A0ABR3ZAR5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Target of rapamycin complex 1 subunit kog1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">KOG1</name>
        <name evidence="7" type="ORF">Cpir12675_002240</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat RAPTOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000041">
        <property type="protein sequence ID" value="KAL1897741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004083">
        <property type="entry name" value="Raptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029347">
        <property type="entry name" value="Raptor_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12848">
        <property type="entry name" value="REGULATORY-ASSOCIATED PROTEIN OF MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12848:SF16">
        <property type="entry name" value="REGULATORY-ASSOCIATED PROTEIN OF MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14538">
        <property type="entry name" value="Raptor_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01547">
        <property type="entry name" value="YEAST176DUF"/>
    </dbReference>
    <dbReference type="SMART" id="SM01302">
        <property type="entry name" value="Raptor_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Raptor N-terminal CASPase-like" evidence="6">
        <location>
            <begin position="132"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="1268"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="876"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="918"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="31"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="881"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="923"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="942"/>
            <end position="957"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1897741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1383" mass="156296" checksum="EAC27947C2761D18" modified="2025-10-08" version="1">MTKSHIDELDKRTQVNQGAMTDDDGRRPSSAPGNKNDGATISTEITRIPKRLPPLLRTKSESHPRDTDSETGHDDEHYRGARHGFEENYLSEDVLVTLASRWQMYYTDKRYETTGKPIVSNFKLEEWRMHDRLKTISAALAICLNLDVEPPDQLRTTPGARMEAWIDPTAPVGPKALDAIGKALQSQYETLAIRTRYKQYLDPSVDETRKFCQSLRRNAKDERVLFHYNGHGVPKPTISGEFWVFNRNYTQYIPVSLFDLQAWLAGPTMFVWDCSEAGNIVNNYPRFVDKHEAEDNEAKAIDPNHQTVNYRPFIHLAACRTGEHLPTNPLLPADLFTCCLTTPIHMALMYFALQNPLKINITPERARALPGRLQERRTPLGELNWIFTAIADTIAWTTLPRDLFRKFFRQDLMVAALFRNFLLAQRIMSTYGCHPQSFPELPDTRQHPLWKSWDWAVDMALAQLPMLELKGKAGIEYEYEHSEFFADQLTAFHTYLAQGDAIKQQPPEQLPVVLQVLLSQQHRVRALILLGRFLDLGPWAVQLALSIGIFPYVLKLLQSTAMELRPVMIFIWTRLLAVDNSCQVDLVKDSCYVYFATILKPHEPIPVADADEHKAMCAFIIAMVCRDYEIGQRSCNSSDIILSCLLHIQNPSNALLRQWACLCLSQLWQTLPEAKWRAIREDALSKLSTLSKDLNCEVRASMLYAMTTFLGIPEITPEVQKIEEGLAWTVLGMANDGSAIVRREFLVFLSTFIVRYESKFVVAAYEQMIEEDLASKTTQCDDTTEARSGLHYALPGDREKDGSIKPSARGLSYNTVFAAMWRVALTMSVDAHPEVQKEASIIVDYVVDAVLQSPVGPNARKLLTVLYRKYTMHSSRHASKNSLMNNASSSTSNTPLSSPGLLRRTASMFFPLGAFFNNEDKPSSTNPSPTTTPANHSHRASSMRNPPLNAATTTSGDQNDDRNSQTHYHVCREPVSGIFQSRDLSEPAKLPLPSTILDWAIGYFREPQMKPVEADEPGSTEYNERLWRRSRNEGILKKTQPLKSFAGSHKWNNQLGMLNNSSQPVKMTFHQYEDHLAAADDGNTVTVWDWKKQGVLSRFSNGNPPGSKIRNLRFINEDDQALLMLGSSDGVIRIYRGYESEDHIQLATAWRALTDMVPSTVNSGMAVDWQQVSGRVLAAGDVRVIRAWDAASEMCTMDIPARSGSCVTSLTSDQMTGNTLVAGFGDGAVRVYDLRLKPQDSMIKKWRDESDRQWVMAVHMQRGGQRELLSASRNGKVRLWDIRMDKPLHTFQTTRDTLRTASTHEHLPVFAVGTSTHTVKVFNLDGQELSRVEPYSSFLQQTRSNPISATDFHPHRPILAASAWGDTHINLFTCENQESEVHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB12</accession>
    <name>A0ABR3ZB12_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Alpha-galactosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_002407</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>alpha-D-galactosyl-(1-&gt;3)-1D-myo-inositol + sucrose = raffinose + myo-inositol</text>
            <dbReference type="Rhea" id="RHEA:20161"/>
            <dbReference type="ChEBI" id="CHEBI:16634"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:17505"/>
            <dbReference type="ChEBI" id="CHEBI:17992"/>
            <dbReference type="EC" id="2.4.1.82"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolases 36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000047">
        <property type="protein sequence ID" value="KAL1897225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008811">
        <property type="entry name" value="Glycosyl_hydrolases_36"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31268">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31268:SF32">
        <property type="entry name" value="GALACTINOL--SUCROSE GALACTOSYLTRANSFERASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05691">
        <property type="entry name" value="Raffinose_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1897225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="848" mass="94422" checksum="91C7675346781CB2" modified="2025-10-08" version="1">MTILDHDVIAQDPENQALYQHVIAQPSAAPDHAIPVQLASYPPLAQVTQLSSQELFFTVVLQVHHSQLHEPWEVSIWSQIGKHGTWQETPMRPALSDASRSAPNFLQDNSARPVLYLSFFHTLKVDKTFSFTLKHRPGPNRPWSWVQHETGMTDGTVIVADTNAPDPPSNIHEIIRGLNPALSIKSCTSQSPGANVWRLELDIDAEKSAESVFVETSIGVPWGSFVRSFGLARAWEPWLYPTRNDGETSQRATLIVSVCRKTENAIAAAIYEARSLVQGFNNTHIEAKQADISYSPSTDDVNATWRETWYDGLGYCTWNSLGQQLTAQKLYNALDQLAENKIDVSSLIIDDNWQSINSKGDDQSKFSMTRFEALASAFPGGLKQTIAAIKSKHPNIKHVAVWHTLFGYWGGVSPNSEISERYQVVEASRRNDMGGPMHVVSANDVARFYCDFYSFLSSCGIDGVKTDAQYTLDIFNTSQDRRSLGKAYQDAWSLACLRWFSNKAISCMSQTPQIIFHSQLLRNKPPVVVRNSDDFFPRVPTSHPWHVWTNAYNSLMTHYLNAVPDWDMFQTDHEYAGFHAAARCVSGGPIYITDTPGQHNLNLIKQITGKTTRGRTVIFRPNTVARAADPYVGYHDNVLLKVISYHGSVSGYPIMGIFNVSSRPLMELVHLTAFPGILESSPHKYIVRAHTTGRISDIMKASSSASLFVVSLDVRGYEIFTAYQISSLENKEGSRADIASLGLLGKMTGAAAILSNMVTKLETGRVHVETFIKALGVLGVYISTLPKMSIDKHFLVTIMAQVIPPHTVTVSTVNPQVLEIDIETAWKEMGLRSGWSNEVQVQIYFDIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCQ9</accession>
    <name>A0ABR3ZCQ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dihydroneopterin aldolase/epimerase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002052</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000036">
        <property type="protein sequence ID" value="KAL1898104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006157">
        <property type="entry name" value="FolB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02152">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00905">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dihydroneopterin aldolase/epimerase" evidence="2">
        <location>
            <begin position="206"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="319" mass="34472" checksum="AD24EC7370D84C3E" modified="2025-10-08" version="1">MDTLWQVGVCAGEPTGSVKVTNLASTIKAGHDAWGRTNKVQPVSISVAVSLRQPFQRATATDNMADDTVHYGQLSKAILAALAVVDQRQSSGNNGFDESITLRAVLDVIWAALTGTTIDGTSTQTFVSPFLNLDYIRALSVSVLFPKASLLGSGVSLTGMAVYKPEAGKLKKQAESEAKAQVEKKEERTKKDDRQETLVQNFGVALKIHEMRVPTLIGLNDNERLGRQVVVTDVQVDRYGEHKDLYTRLEAIVQKSMDDSSFGTLEALASKVAGDIKQGFLAGREAFTETKTCWQLKLSMTKPTAVPLAEGACVELVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDG6</accession>
    <name>A0ABR3ZDG6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="13">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">SSL2</name>
        <name evidence="18" type="ORF">Cpir12675_002043</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. RAD25/XPB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="13"/>
    <dbReference type="EMBL" id="JAWDJO010000036">
        <property type="protein sequence ID" value="KAL1898095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18029">
        <property type="entry name" value="DEXHc_XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18789">
        <property type="entry name" value="SF2_C_XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050615">
        <property type="entry name" value="ATP-dep_DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032438">
        <property type="entry name" value="ERCC3_RAD25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001161">
        <property type="entry name" value="XPB/Ssl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032830">
        <property type="entry name" value="XPB/Ssl2_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00603">
        <property type="entry name" value="rad25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11274:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11274">
        <property type="entry name" value="RAD25/XP-B DNA REPAIR HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16203">
        <property type="entry name" value="ERCC3_RAD25_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13625">
        <property type="entry name" value="Helicase_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00851">
        <property type="entry name" value="XRODRMPGMNTB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 18" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="16">
        <location>
            <begin position="360"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="17">
        <location>
            <begin position="576"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="264"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="778"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="273"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1898095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="842" mass="94256" checksum="7FE073207DCCCC45" modified="2025-10-08" version="1">MSLAAKRKAPGGTEGALKAGRLSKGSTPGAATPRSNVGVDDVEVVEARDIPEDLNKAIARNIQKFDISAFPYDLNSGIKDMATGFFEPTHKRDFTGLRLKPNHQTLPLRIDGWGKLVLESFHPLAPRVQDFLITIAEPTSRPHFIHEYRLTTHSLYAAVSVGLNPMDIINTLDRFLKTDMPPNVKEYIAYCGRSYGKVKLVLRNNKYYVETTDANVLQILLKDWEIGSFRVQGAEETTTVAPTMAGLVIAGTKDAAGVREAEGLKEAKANGEQQQQHSQQIQSHAAEEDDDDDVDSQEVIHAFQIKDEKVGATAQRCLALHYPALEEYDFRNDHINPNLEIDLRPGTQIRPYQEKSLSKMFGNGRAKSGIIVLPCGAGKTLVGVTAACTIRKGVVVLATSNMSAIQWRNEFLKWSNIDPDSIAVFSSDSKSVFTGNTGIIVTTYSMVTNTRERAHESAKMMKFLQSREWGLMLLDEVHVVPAQMFRRVVGSIKSHSKLGLTATLLREDDKIEDLNFLIGPKLYEANWMELSQKGFIAKVQCAVVWCPMPTEFYEQYLKASARSRSLFCVMNPSKFQACQYLIKYHESRGDKIIVFSDNVYALEVYAKKLMKPFLYGGTSNAERQEILEFFRSSPNCSTLFLSKIGDTSLDLPEATCLIQISAQYGSRRQEAQRLGRVLRAKRRNEEGFNAFFYSLVSKDTVEMSFSSKRQAFLVDQGYAFKVITQLKNIENTPDLAFATPESRRELLQKLLVDQESKSWKDEEKEAAGLAADGNMFYGPDGKPLRRGTRRTAGSLKGLSGGNDMAYIEQNKSANKALMKKKKTHAGFFKSLQRENEKRRKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE98</accession>
    <name>A0ABR3ZE98_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Bilirubin oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_001781</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000030">
        <property type="protein sequence ID" value="KAL1898674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13889">
        <property type="entry name" value="CuRO_3_BOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48267:SF1">
        <property type="entry name" value="BILIRUBIN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48267">
        <property type="entry name" value="CUPREDOXIN SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046894725" description="Bilirubin oxidase" evidence="8">
        <location>
            <begin position="21"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="11">
        <location>
            <begin position="75"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="9">
        <location>
            <begin position="225"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="10">
        <location>
            <begin position="363"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="532"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="680"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="744"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="538"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="551"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="571"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="587"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="744"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="781"/>
            <end position="797"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1898674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="797" mass="87521" checksum="808C864EFFFF86A7" modified="2025-10-08" version="1">MPTIVSILKLAVLAATLGDARDWVSPEYRWLYTQSLPIPPVKQQKWPDQVFHHNATGTPIKYYELNEVDFTQQIYPGRSATRLRGYDGMVPGPTFIEEKGIESVVRVTNQLNSPVQRAPWDGWADDRLQPGQAKDYYYPNSQVARTQWYHDHAAHITAQNVYLGLAGFHILQDENEAALNLPGPYGKYDIPLAITSRQYDANGQVVFPRGEIDNIPGDIIHVNGAPWPFLKVEPRKYRFRFLNGALTRTFKLSFGLDTANSTKASFNIIASDSGLLSSPQQADTIYISNGERYEVVIDFSQYKGENITLNNARGQIGEDFLHTDKIMRFVVASNAEVADSSAVPSTLAAVNYPSQAVSRSRTFTFAKTNNLWTINGISWNDVRARILSNPIRGTVETWELINDSTENHPVHVHLVDFQIVSRTGGRRQVFGYESSGLKDTVWLAPRERITVRAYFGPWPGVYMFHCHNLVHEDHAMMAAFNVSLLEAYGYQDEDFSDPMEPEWAPRWIEAAAYQYSAVAERIAELTENTPYYEYDTSGDGGSESGSGGSGTDTDSGTDSSSGSGGSSDSNSDSDSDSDSDSDSDSNTRPTTAAPPRTGSGAPTRTRTNRHARPTWAIGRPDGETRSNKTRGQPQPAALESWSNFVNGHWKTQAVTTEALTTPPATGTFQDTQPIKTLTAPAALDTPAPIETPPLTGGANPLETPGPSIPNPAPTSALESDKLAASKESCSPIIVYTTLTTYVVPPPSSLPPSPPPASLPPTTPTASSSPFLRRPFGPSGPHRYKWSRPHGPRHNMLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEH7</accession>
    <name>A0ABR3ZEH7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Transcription factor TFIIIB subunit brf1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">BRF1</name>
        <name evidence="12" type="ORF">Cpir12675_001604</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000026">
        <property type="protein sequence ID" value="KAL1899048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20554">
        <property type="entry name" value="CYCLIN_TFIIIB90_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.650">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011665">
        <property type="entry name" value="BRF1_TBP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618:SF4">
        <property type="entry name" value="TRANSCRIPTION FACTOR IIIB 90 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07741">
        <property type="entry name" value="BRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0010">Activator</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Cyclin-like" evidence="11">
        <location>
            <begin position="151"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="11">
        <location>
            <begin position="249"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="380"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="490"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="662"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="723"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="403"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="435"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="503"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="726"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="744"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="781"/>
            <end position="793"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1899048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="793" mass="86416" checksum="25D3347CE1D535FE" modified="2025-10-08" version="1">MSSFLTPMKRAPMPGGAAQPIRPRAIQRPNLVRAMRENDQRRYALTTAAAAAAASTAVKPSISTSGRTQCPNKSCPKSDVVEGICRSCGRVVDDSNIVSEVQFGETSSGAAMVQGSFIGPDQGGVRSLGPNFRRVGGSSEDREKTIRDAKMFIAGFAHQLELSESLINSAVQAFKLASNANFIQGRSLAGVAAVCLYVACRNEPPCKIMLLDLADLVQINVFKLGRTFKAFNKAIPICNGGFDPVYPEDLIYRFATKLEFNTMTSKVAEDAVRLVRRMSRDWMVMGRRPSGICGACLLMAARMNNFRRTVREVVYIVKVTNHTIQNRLEEFKVTESSNMTVEDFLSQDLLESSHDPPSFYKNAAEYQAKLKERIRKRKRRITDELGPERQALPALPPSPPTPSATISSSSNTPSLTTTAATAAAPASLPIDPAMMPNPTPPEPAEQPPRLDADGFAVPQIPTANGDINAMALADPEGEAALSDLARNFGDQPARQTADRSTEQDDGNDEDNDNDNDNDNGESQDGKAPSGDVGLGLTKDGKPRKRAPKSVGPKIPLDPEWEADELDLEAQISEIFNDPHTTEHAKAFETAQKRAQQHSQWALSQEPKKEVSMAAEVCEDEFANDPEVSCCLLSEEEVRIKELVWSNHNKDWLRTQQEKVFRLKLAADKPKQTRRRKKRPRMGEGQAEPADTPADAAVSVMKERAISKRINYDAIRSLFDIGEEDTQTGASSTRPATSYAGSAAGEEEPDQDEAEGGAEDGYDDMDGDGPGSPVGSDVYGYGDDDGDDYGYDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEI7</accession>
    <name>A0ABR3ZEI7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aspartokinase</fullName>
            <ecNumber evidence="6">2.7.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_001582</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-aspartate + ATP = 4-phospho-L-aspartate + ADP</text>
            <dbReference type="Rhea" id="RHEA:23776"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the aspartokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.4" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000026">
        <property type="protein sequence ID" value="KAL1899026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="entry name" value="Acetylglutamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2130.10">
        <property type="entry name" value="VC0802-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054352">
        <property type="entry name" value="ACT_Aspartokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001341">
        <property type="entry name" value="Asp_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018042">
        <property type="entry name" value="Aspartate_kinase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00657">
        <property type="entry name" value="asp_kinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21499">
        <property type="entry name" value="ASPARTATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21499:SF59">
        <property type="entry name" value="ASPARTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22468">
        <property type="entry name" value="ACT_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="Carbamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00324">
        <property type="entry name" value="ASPARTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="7">
        <location>
            <begin position="473"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1899026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="536" mass="57831" checksum="E0244A80F7D5D63B" modified="2025-10-08" version="1">MSQLLDNAGDLGWVVQKFGGTSVGKFPDKIAVDIVRQYLSRNKVIVVCSARSTGKKAEGTTSRLLTVFSKLLSIGSHYHTEEHRLELVEDARALVKAICDDHLQAVSSFIKSPEIQATLTAEITRECDELVEYIVAAKRFNLEIKARAKDRVVSFGEKLSCRFMAALLQDVGVDAAYVDLSDRLHFDLNARLDANFYAAATAGLRAAIDECGAKVPVVTGFFGNVPGSLIDGDIGRGYTDLCAALCAVGVAAEELQIWKEVDGIFTADPTKVPTARLLPSITPSEAAELTFYGSEVIHHLTMEQVTHAQPPIPIRIKNVKNPLGNGTIVIPDGGSPSGKHVKPKAIDTTDLDKDYYRLEPSVETNGVSDAAQDSAISKSIPKRPTAVTIKDNITVINVHSNKRSISHGFFARVFNILDGHKISVDLISTSEVHVSMAVHAACIELGVFDSAIKALQVECGEVSVLPRMAILSLIGAEMKDAIGISGKMFKTLGDHNINIEMISQGASEINISCVIDAANATRAMNVLHTHLFTFLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFH7</accession>
    <name>A0ABR3ZFH7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein BIG1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Cpir12675_001437</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BIG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000022">
        <property type="protein sequence ID" value="KAL1899401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037654">
        <property type="entry name" value="Big1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046756">
        <property type="entry name" value="VAS1/VOA1_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28285">
        <property type="entry name" value="PROTEIN BIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28285:SF1">
        <property type="entry name" value="PROTEIN BIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20520">
        <property type="entry name" value="Ac45-VOA1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0732">Signal</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047365008" description="Protein BIG1" evidence="11">
        <location>
            <begin position="19"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="V-type proton ATPase subunit S1/VOA1 transmembrane" evidence="12">
        <location>
            <begin position="224"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF20520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1899401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="273" mass="29615" checksum="5493EC5B29E905F0" modified="2025-10-08" version="1">MRFSTLAGTFALCATAQAFPDTSPFILSSTASLDMPATTDQLQSNAHVLKTAKELLSTCPTNKYVVISQPMLHSQDLASASSSPTLHGIVKGSIVKSTYSVAGMYGEIASEDVLTYIRAACGSRYDRGEISISSLPLQALPLDTASTDERDEVLLDNDRIIADVLATAPLGDSYTILYLSDVRDLKYEAQFETVFSSDLKRDEAYSRRANASADHRPFFEKYELFNAGIYMALVATSFLLMILFVGLKALGSLEVSVGAFDKDMGPSAQKKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG36</accession>
    <name>A0ABR3ZG36_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_001556</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000025">
        <property type="protein sequence ID" value="KAL1899272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF119">
        <property type="entry name" value="ROA1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="411"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="525"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="562"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="641"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1057"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1144"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1167"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1196"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1286"/>
            <end position="1304"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="75"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="713"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1899272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1310" mass="144123" checksum="F0EA58BB09F693C5" modified="2025-10-08" version="1">MSSLVESVHSETLDKTLDPESPSPILAEKPLPSPPHTEPPFPQPSLSFKDVRPANLQIRSLGVSLDMTPSWTDPASYPDLIKSRFKPQSRFKPLLQHVSASCCPGTLTAIIGGSGSGKTTLLNTVAERVNESRLIVSGCVTVNGLSGIHAARHAYVMQQDVLLPSLTVRETLMYAAALRLPKSVSEKERADVVEQVILELGLKECANTRIGNSQHRGCSGGEKRRVSIGVQMLANPSLLFLDEPTTGLDATSAFQLVRTLKALTAKGRTIVTTIHQPRSEIWHLFDNLIILSKGSPVFSGSRESCVSWLDSQGLSLPPFVNPAEYMVDIAAIDNRSLELEEVSRIRVDSLKSAWKTESDRLFNDMADTSNGKSNIDHNNPTSHPIYEHASFITQMQVLTKRTLKVTYRDPMGMMSAMLETALMGLVSGLIFYNLSRDASGIRSRQGALYSSSAMQGYLILIFEVYRMTVDIQTFDCENGQGCVDPWAFILSRRVARFPTEDLPVPVIYSVILYFMANFDPEINKFFIFLGISVLNHYIAMTCAMMCVALARDFPTASLTANLIYTLQTLACGMFIQIDSIPVYLRWLKYITYGWYCFGAYVGNEFEGSFYDCPYDGGESNPSCAPYTGSEIMRDLSFPRDWVARPSAVLASFVLLFLLATYALLRFKKTTMTIARARNSEDVDLLDSKETVVIEPMPDVAAIDLSLEKFSLYLDKRSLLGKKLPRKTILRSVDATFQAGVLNVIMGPSGSGKTSLLNSVALRLQNTMRTRYIPTGRLLFNGTGPSDSVVRAVCSYVCQDDDGLLPCLTVRETLRFAAGLRLPTWMSKEQKQRRAEDVLLKLGLKDCADNLVGGDLIKGISGGEKRRVSIAIQILTNPRILLLDEPTSGLDAFTASSIMEVLKGLAAEGRTLILTIHQSRSDMFGHFGNVLLLARGGMTAYSGPAAGMLGYFSSRGFDCPSHSNPADFVLDLITVDLQQAQREEESRTRVQALTEAWKQGGGVSDEKLIRARRTFTGKTLATPAELGAMVRAPSPFSVAAPLLINRAIINIRRQPQLVIARVMQAVSLAILLVLFYTPIKHNYPSIQNRMGIVQQIGSFYFSGMLQNVALYPYERDVFYREYADGVYGVTEFLLTYTAMEVPSEIASGTLAGGVLLVMVIGLPRTALLFFTTSFASFGVISCGESVGIMFNTLFNHTGFAITLTSVVLSLANSMAGVLSTDMPAFLDAMNYLSPVRYATRIVAAYSLRGVKFTCDDTQRRPDGRCQIATGEDALELYRLNDDPVKNGIALAACVVIYRLLAWGLLKAVKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGM1</accession>
    <name>A0ABR3ZGM1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ATP synthase subunit G atp20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ATP20</name>
        <name evidence="10" type="ORF">Cpir12675_001453</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase g subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000023">
        <property type="protein sequence ID" value="KAL1899337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006808">
        <property type="entry name" value="ATP_synth_F0_gsu_mt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04718">
        <property type="entry name" value="ATP-synt_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="4" id="KW-0138">CF(0)</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1899337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="178" mass="18686" checksum="8B699C0C9D94BAA8" modified="2025-10-08" version="1">MSAIRPTVRALRMPMSRRLQSTSTPSGAADKAIAGLSKAVNAAGPMVSGTVKALGKAGGRTGQAVAIIEKAIPQVTYYSKVGLELGKFVAKGRNMELPTMATFQSYYLQAFNALKQPAKLIACAQQSLIALRSGGITKVQAATAGVLIAELLGFFTFGEIIGRFKLIGYRGETASAHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI12</accession>
    <name>A0ABR3ZI12_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Macrophage colony-stimulating factor 1 receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CSF1</name>
        <name evidence="5" type="ORF">Cpir12675_001037</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000014">
        <property type="protein sequence ID" value="KAL1900353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029636">
        <property type="entry name" value="Csf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056779">
        <property type="entry name" value="Csf1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048636">
        <property type="entry name" value="Csf1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32085">
        <property type="entry name" value="PROTEIN CSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32085:SF3">
        <property type="entry name" value="PROTEIN CSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25038">
        <property type="entry name" value="Csf1_C"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21678">
        <property type="entry name" value="Csf1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0675">Receptor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046384764" evidence="2">
        <location>
            <begin position="19"/>
            <end position="3396"/>
        </location>
    </feature>
    <feature type="domain" description="Csf1 N-terminal" evidence="3">
        <location>
            <begin position="2"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="domain" description="Csf1 C-terminal region" evidence="4">
        <location>
            <begin position="2666"/>
            <end position="2808"/>
        </location>
    </feature>
    <feature type="domain" description="Csf1 C-terminal region" evidence="4">
        <location>
            <begin position="2881"/>
            <end position="3066"/>
        </location>
    </feature>
    <feature type="domain" description="Csf1 C-terminal region" evidence="4">
        <location>
            <begin position="3108"/>
            <end position="3388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="499"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1126"/>
            <end position="1248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1652"/>
            <end position="1676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1770"/>
            <end position="1802"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2455"/>
            <end position="2477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2603"/>
            <end position="2668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2809"/>
            <end position="2865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1181"/>
            <end position="1227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1228"/>
            <end position="1238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1661"/>
            <end position="1672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1770"/>
            <end position="1781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2605"/>
            <end position="2626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2821"/>
            <end position="2831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2847"/>
            <end position="2865"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1900353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="3396" mass="375578" checksum="DB65CC0A6F16BD5F" modified="2025-10-08" version="1">MFFLLYLNRLFSYLVSYAIRTYTWHKHHIYVEIQALQISLLAGRVFVSGVRYHGENEAFHIQQGYFTWCYWLRNVRNLGQLNDRLQDTEGQETSTKALPCRFAAHLVGIEWFVYNRTPIYESMLEGLLHNSLPQTGPSSLEIHDTSSIRRRATRISDETGADEAYSLHGNTSSANLQNPVDAQASHGAGSDNEKPSTTDESEIPLLLRVFPIHLEVNKAAMVMGNEHTKAVLVVKADDLSGDIDAISTDTPDPYRQVFNLRFKHPVVEIRQNADYREEQTARATRERRAAQTTEPVTKKPFFSWLFGRCVSSFHNMMPRWKYSMEPATASAHTPIDTATSQPAGASQWQGLSRYLDDQAQDDKARWAHVEYAAEPVIVDSPSATMCIYWDSPTKVPELPDPALRSKEDPYATNINGEIPPAWGINMTIKGGVVNYGPWADRCRAELQNLFFPNLCKDAIPTPAIRAGEYRVPTQFRMYIQLDDNVTVRILTQEDSKNWKWKGKAPMPTDAPKRRRRDKKGAKPEAMPTQTRQPGWLEFKVSPNSTINYSMDMVAGTKGYSTTVDVDFPGTEMSSSVNHQILLRSGPFKVSCDMGSPLQWNALRSWNFGISSDDIELFLLRDHIFLITDLVEDWGSGPLTEYLVFTPFKYLISLDFRRFKLYLNVNDANVIDNAISTNENMFLVLGSSAMAASLTIPIDQFRPPKNAIPFEVRLDPLMISLQLPPWNTQAAFMPSKEIGQAESLVACGKYEYNATTSVANTDTLVLDISIQSLVVKLFGSVLRYGLKLKDNYFGDDLHFRTVQEYQDMLQLREYNPSAETANRAPYKKSNDMDVVMAVKLDDTKIFVPGNLYSAERNIHVEMASITADARFTNYYMDLELIISPISLALGAFQQESDISTVSSTTTQMFIDGVRVFGNRLFGLPPSEPTYMCNWDLGIGAVTGECNAEFLAALALGGQALSFTFDDEENALVSFSSIVYYDVTFLRLHVDAVKLWVHVDEAAFLLSTGRIDLNYNDWARSHYSKKATISLPDIQISCINTEDSCSSRAKHLGCGSNSTSRANQTFVPAEADVMVKTQVQLTMIGRKFKFTEERKKQQELIRREDQRTQRIPFLLFPEYASDYMPEAVDPPAQNIPPVPHPINGEFLGDDQASSIRTGSSARSHRSQRTQQSRIIPKTGGGSTLRRQSSFLSFSSTASSSKSVLRPSDSSGSRSRSQISHSQPQSQPQSRRGERWRDAARRSSTYSEMTESIHEAQSSAVFSSQYFTPSFTLENVVPQSRDALALAIAEEQADYGDFMVADFPLEDIDPNSLGEDHTYTGFVVEFSRGISGFFTPASVQHTTKLLSALQPSSPDDILDSLHLSSMEDILRFKKEADIRGSILDIMVCLPSAHFRFLNSSSLDSPGPLLEEQDQYDVQLSKLAVVMRNTESWGDAFKAETRNDRMSFRASFGNMTFSASERLNGGVEPQAAVQAHIDGATFSMGSRDVTTVDTDIGNITCNMSSSKLQYLASLIHRTDVLVKSMGTTVEEVVSSHKNRVQFFVQQLLAQAQRIPDPPFIVRPSAVLRSVPGHLRVHDSWKMVQRLRQIWSKMDSLARDELLTACLEPHPMPPDDVQNQIIAMFTKWRGWDLGPLSDSVLIRRIFDRLEKDSVDAANYRAPRGHSSTLPSTSSPPSIDKNPPLLMTCHLGEIELVLDPGPKQNRASLMGLTAKIKSNDSQNLPPDDFDISNFDEPSTTVINLHCREAAVKINWELCELVDDVLELYNRTGANSASSLGANRSVNPASPRGKPVSKKGIHPASTPKHLPKPKLHIVVAVGKSSLDLDTINLHSTILCSGINGSILVDNHLGETKTLNVIMSSHAVTSSLFSHSLKLGMFQLQEPSLFISHEERETANMISHVVKCAPSSKSMSLLVKQDPLALFEVADLLIKDEFARLYKIKTSIIAKFAKTPTASPKAAASLKIIGQLSSIKINVAMFLNDYNVTIPLCQNLAYNIQGVVARAAVATNYGKELIFDFDIKENSHSFGVGSGLNVHEVSLIQIPPMNGRVLSVISPTEHTISVATSLEMVQLDASAVYSLLMLPNKAQLTAEIEDMQVMAQALKRHFNDIVDPDQIGSPLSGPASKPSIVVSTEPTPKPLVYKAHVSLAGLHVFGKTSLVSDPDPLAYVSFSLEKVHVEVTNQAGPGQPIFDSPQINLNLSHIGFDMRKGHEAAMRSCGSLVFSALLSMSLSGLGPAPGSGSSTGHDQCERWFSFQTNGLEIMLSPETVSTAIDIMGHMGDKIKDLDTTRERQYLRKLRHSKPRISINNTQDESSDTDLFDSVLDSFVYHFQIRDITLCWLVSGAMEESVGQEDLVLTVELIELSTRKSKSACLEIQNMQLQMVPVDEVKTSVRSHHSALLPEIIFKIASFSSGRSRKLAFQAVGKSVDVRLTSGFMIPATHLQDSLTRSASNIQKATENWSHPTPVDSISSPSTPTGLSSNTIEKRIGLSRKRVESLLIHADFAGAILHLSGRRSPPVPSLAGFSNDKPTSTPYCRTTSAGKYGQFKTDESNISATLHSPGLAWRLEYRDNGTDKPSLNGEIKVEGSSNTLHPTVVPLIMDMSSSFKEVVSEQKSRNDKKERQHEKAQTEKKKRSRTSETTSSWLGTVVTTDRKDNNKDSNSNNTALDDNSMLGANPSSVFGKLNINIGLRITKQEFSLSCQPIARVAATGSFDSIYMAINTVHSNELGSFLTLTTSCSNLQASVQHVYSRDSTASFAVDTIVLSLMNSKHFSGTAGVSALLKVSPMQVAINARQMQDFLLFGEIWYPKEMRGNRDDGGGVVPMQQASVPTTDSTLVPVPVPALHRTTKDASQSNPDSPSAPSSPIEPTTAAPNGHFVQIYQQVSATAAFPWTATISIESLDVDLDMGQAVGKSVFVIRNFWVSSKKTSNWEQNLCLGFERIGIDSTGRMSGFVALHDFKLRTSIQWPDREQIVSLTPLIQSSLSFDQFRLKASWDYQAFLVADITSLDFLMYNRRGPNGDRLVAILDGEAVQAFGTPSSVAQGASLYRAILKFIQERKASFELSLQEIEKFTKRRSLINALTVAVATAAASSPNQESPADLLSTQGTLAESDGAISKAPISLDTDVIVTLKAVNLGIFPSSFTDHQVFKIEALNAHARFAANFDEQRLHSLLNLTLGQLRVGLASVNSDPPKNSSDLSVKEVVQRSTGARGGTILKVPRVHAAMETWQSPQTNKIDYIFSSAFEGKVEVGWNYSRISFIRSMWASHIQSVQDTWGKTLPLANSIKVTGVPDATTATVTATVPTKSEADEAEQKRKITAEVSVPQSKYEYHALREPIIQTPQLKDMGEATPPLEWIGLHRDRLPNLTHQIVIVTLLELAGEVEDAYSRILGSSDRAWTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI30</accession>
    <name>A0ABR3ZI30_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000015">
        <property type="protein sequence ID" value="KAL1900054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="227" mass="25870" checksum="A6E0C9D36BEF188A" modified="2025-10-08" version="1">MRVTKAKAFAHSKGPGAHHQQHPQSQQIQKQQQQQQQQNHRHHDRTHPPLTHVRRASSQHSSPGRPRPRRASITTSILRPRRKRCSEPDVVTRSSVLQNPLMRHDQRDREGDSEPELASFSAHSISAPSSPARSRQNKQSQASHVPQAPQRPPPPPPLQQPQLQSYQQIFPHPRLVVPSLSENDYTDLRNMFCRSSQSPPRSRELSPLRKSTSLQPGLVREQISESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZID5</accession>
    <name>A0ABR3ZID5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ACB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_001066</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ACBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000015">
        <property type="protein sequence ID" value="KAL1900067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000582">
        <property type="entry name" value="Acyl-CoA-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035984">
        <property type="entry name" value="Acyl-CoA-binding_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23310:SF62">
        <property type="entry name" value="ACYL-COA BINDING PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23310">
        <property type="entry name" value="ACYL-COA-BINDING PROTEIN, ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00887">
        <property type="entry name" value="ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00689">
        <property type="entry name" value="ACOABINDINGP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47027">
        <property type="entry name" value="Acyl-CoA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51228">
        <property type="entry name" value="ACB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACB" evidence="3">
        <location>
            <begin position="10"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="109" mass="12031" checksum="66754A4E24E02961" modified="2025-10-08" version="1">MPAPVATVPLSPEFEKAIVDSKKLTSKPSNEDLLELYGLYKTGTGEKFTDAPTPGMFELKNKAKYNAWEAVHKEGISVETAQSRYVAKVEEMKVTYGYDENKVPETVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIV7</accession>
    <name>A0ABR3ZIV7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Bud site selection protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">BUD6</name>
        <name evidence="5" type="ORF">Cpir12675_001220</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000017">
        <property type="protein sequence ID" value="KAL1899996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1540">
        <property type="entry name" value="Actin interacting protein 3, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022782">
        <property type="entry name" value="AIP3-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005613">
        <property type="entry name" value="AIP3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056279">
        <property type="entry name" value="Aip3p_Bud6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051825">
        <property type="entry name" value="SRCIN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22741:SF10">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN CG32809"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22741">
        <property type="entry name" value="P140CAP/SNIP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03915">
        <property type="entry name" value="AIP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23153">
        <property type="entry name" value="Aip3p_Bud6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00806">
        <property type="entry name" value="AIP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Actin interacting protein 3 C-terminal" evidence="4">
        <location>
            <begin position="429"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="118"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="180"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="316"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="564"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="768"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="740"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="132"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="207"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="243"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="356"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="564"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="777"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1899996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="939" mass="102528" checksum="2D34161D10EB9A15" modified="2025-10-08" version="1" fragment="single">TSSGGTSSSLSLIEKGVTRLLVATKRLLEILTKWSHNQATDSQVSDVYVRLGYEFNMACRAFNAINVSTTDLGNVPQELRNVLEATLSQEASPESLDRYLPQIRDIIIKLLQGLRHKQQSLRQRHRGDRDSGGSGGAATGGAGPERITSVSTTASGASGVSAASGASGLTNMIEDGLENGYSDVRRGDSQASSYRHNSTRERHARSSAISDIDSNGTVQHAPPPMPPYPESGAPSGDFALDSFPPPPLPPPKETQTPADALAKLQKEGVLERRASRRYSQYQISKVLNSQAVPMMPQNATNLPGRPNNKDKQEAMLAVQTRRDSVISRHSRAASNLSRSGAADGSPAPVRAPGRQLQESVSVTELPSQLDEPNWPKPRMNKEMPPVPEEDANSPTRSGMAKKPRTPEKKSISSSPPPSEPQTPKDLTLFLQYKSKIKKFVLPEGRKELSIGRLQLAFIEKFSWNTHHNGVDLPEIYIQDPVSGVRHELEDLSDISDRTVLVLNVEALDEVRRHIDEGLGGIRKLVEQMKENVDVQGAAIVRVSEKQQETAKEIARIASAPPQTIIQQGPPIVGSSPRSAAPAGSKLGSGDISEIKVLRRDLAVLRQTYSSFQADIESSMSNLRAKAANIKTAVVKTIIPDIDGDAGYSYVANGRKKLNSDSDRLVGQVDDLQDLVEDLRKDVVHRGVRPLPRQLETVTKDIVLLTKELSQMDEYLKNERPLWTKIWEKELEDVCQGRDELRLMEDLLVDLKDDLQKASETFALVEQATKEQMKDNGTGASAGSARSFSKGLNNLGNSQDQSAAKDGVLGEVRALQPNHEDRLEAIERAQKLRQKELATRMTNDLQKEISSFVDSGKLKKSGGFEEVERARRAAEEKVRRDVWGTSAGGVLEDEDLDGDEQYAGDVTITPTYDADADLDDDDMGDFVILADGTVVPASAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ09</accession>
    <name>A0ABR3ZJ09_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Serine protease EDA2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_000827</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008758">
        <property type="entry name" value="Peptidase_S28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010">
        <property type="entry name" value="PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010:SF117">
        <property type="entry name" value="SERINE PROTEASE 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05577">
        <property type="entry name" value="Peptidase_S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046342770" description="Serine protease EDA2" evidence="7">
        <location>
            <begin position="21"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="580"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="580"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="607"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="616" mass="69890" checksum="1D8BA9AC287D69B8" modified="2025-10-08" version="1">MKLAWPLAALVSLASAMIDANHMLNKHYEADLVSRGLMKRANDDFYPPNVHDPDAMLTSIYLAQDMEVPINHFLDNPRYAPHDDSMFRLRYWFDDRFYQPGGPVILMSAGENNGQSQLSYMQDGLLARMAMATNGIMVILEQRYYGSSVPTPDFTTKNMRFLTTEQSMADIAWFSQSVVFPGHEQRDLTSENTPWILYGSHYSGSLAAFTRQNYPSLFTGAITSSAMTYAVEDFGDYYEAARRFAPENCATVTQAIIGLVDDIILSQNPQDKNSLFGLFGLTGLTDIDFVNVLTSGINSMIETHWNIKRGSFKWDTYCHAMNSRVRVYNTNENSEKAMRLLVGRYGPMYNLESATNSLANFIGWNHEWVISRCKENRAECFSRPPSIYKRSGLEETWRPWAWQMCTEWGLFQTSTTPSRDVMPVISRILTSRVSRQICYKSFSILKGPDTSQINNFGGLGFKFPRVAIINGEMDPWRAATPHRIGNELNIPQNSELYHLIPGAGHSWDMSSVHQDRVIPGEHPPPAIAEAQGYEIRLAQQWMWEWAIDRASREIIPGYDEDTFDYVNDYGKYFVADESYYSDSHPSPSNSNPSVNSPWGISRESEMKSTASSAINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJL4</accession>
    <name>A0ABR3ZJL4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Multisubstrate pseudouridine synthase 7</fullName>
            <ecNumber evidence="5">5.4.99.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PUS7</name>
        <name evidence="5" type="ORF">Cpir12675_000717</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase TruD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.27" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160150">
        <property type="term" value="F:tRNA pseudouridine(13) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02576">
        <property type="entry name" value="PseudoU_synth_ScPUS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.20">
        <property type="entry name" value="TruD, catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001656">
        <property type="entry name" value="PsdUridine_synth_TruD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011760">
        <property type="entry name" value="PsdUridine_synth_TruD_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042214">
        <property type="entry name" value="TruD_catalytic"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00094">
        <property type="entry name" value="tRNA_TruD_broad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13326:SF21">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE PUS7L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13326">
        <property type="entry name" value="TRNA PSEUDOURIDINE SYNTHASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01142">
        <property type="entry name" value="TruD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037016">
        <property type="entry name" value="Pseudouridin_synth_euk_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50984">
        <property type="entry name" value="TRUD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TRUD" evidence="4">
        <location>
            <begin position="361"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="190"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="675"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="78"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="689"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="711"/>
            <end position="722"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1900841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="768" mass="84203" checksum="49BD254212C96DC6" modified="2025-10-08" version="1">MSRGQNQNQRSPPDDVAIGITERVSSSEFSWSGTLRRRFTDFLVNEIQRDGTVLHLKDFTPVEVTHMKRGQKEVAKEQATTSASGDSNITAASGFETPIEPVVPEAPAVSEDDKAILTELLGSEAAESFLNLYSSSFIPNTLAGRKGPSASSPTINDKALRSKIHQEVRRIFNSALDTTTNNDGAIVATIMPKKGGGRGGGNNGASGGIGRRGDGGGGRSSNFRQIDCPGTGDYLHFNLYKMNRDTMEASAQIAKQLNLKPQMIQYAGTKDRRAVTVQRCSVRRRKPHELDRLNSRLYDICIGDFSYNPEPAHLGMLAGNEFTIALKGCSFPNDAQLSTADKVSRLDLNINAALAHMHENGWINYFGHQRFGTFAIGTHEIGRMILSGDIKAAIDGLLWYDDALANRLDSSTCPIERSIKDEVTRSWACRIFRQTANGEEALRRLPRRYGAETTIIRHLSQHPTDYMGAILHITRGLRTMYLHAYQSYVWNHAASKRWVLYGNKVVAGDLVYDASAQQSKTGGNGTSANQEVELDQDGEEVLNASRDTNIGDEDDDQSLYARLVTPEEAANGTFSIFDVVLPTPGFDTLLPANEIGDFYRSFMKQHGGIDPGNMVRPQREFSLAGRYRRVMTKFLAPPSGFVKACADEMEQLAPTDLDLIKEKLKQKIANETTATTEATTVDMNSSTDTKNEGEPLESKKRPRSSSDLDSSIDKKAKVDESGKAVTPEAEGEKNSIAAVVKFQLAKSAYATVALRELMGVPLAVTEDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK29</accession>
    <name>A0ABR3ZK29_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000756</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053203">
        <property type="entry name" value="Cisplatin_resist-associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022024">
        <property type="entry name" value="DUF3602"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34693">
        <property type="entry name" value="PROTEIN PAR32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34693:SF1">
        <property type="entry name" value="PROTEIN PAR32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12223">
        <property type="entry name" value="DUF3602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="131" mass="14230" checksum="0F99112B67E64D84" modified="2025-10-08" version="1">MVLYSSHGRGGVGNMADKRLSPPLTAADLVTPTVKTAVYSTGRGGSGNMARNTDPLETRMRQDVEEIPRRRFSGSVQHSGRGGAGNIVNTEDLERAEIPHMTLDTGESLVSGSERRRSTEVIEKAKAFFRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKI3</accession>
    <name>A0ABR3ZKI3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000008">
        <property type="protein sequence ID" value="KAL1901171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="109" mass="11898" checksum="622E825EBCBADFE5" modified="2025-10-08" version="1">MSSQGAGSIPFTYTPNNDGYRLLELPSELAAMLDSPNAPTNLTHDRLSYSDDQERDVSASPQKQGITAFATIHESIELIRQASDKPPDKAAAKPAVSVGKWHERFGKTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKQ6</accession>
    <name>A0ABR3ZKQ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000614</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="98" mass="10950" checksum="915E5DCD4AE7271C" modified="2025-10-08" version="1">MNFIRILAHFEDVIVAHILRQPGFHRAVGKIQRSVDDLRYGRNPDEPLRPGEATEEHQAPIGTGPGGSAQQGGSFMTHFMQELRNQARGVPTPDEKHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLE6</accession>
    <name>A0ABR3ZLE6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NAPDH-dependent diflavin reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TAH18</name>
        <name evidence="8" type="ORF">Cpir12675_000417</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF10">
        <property type="entry name" value="NADPH-DEPENDENT DIFLAVIN OXIDOREDUCTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="7">
        <location>
            <begin position="163"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="574" mass="65158" checksum="46ADCDD634A1B1E2" modified="2025-10-08" version="1">MMLVLTLHFQRFNWASLKLSKRLAQLGASEAFPRGEGDQQHPDGIDQVFIPWLASFRQFLLEEFPLPPGTEPISELEALPPQIPLIFTDRKVEPLLLSPHTQEPTELEIENPQTSNLEINTMKDPNDILGERTPETQLACKFGMMEISKPTLETPSNVPIETPSCIFAKLSCNTRITPKNHWQDVRLLKFQISAAGQDPGNKVPAFMPGDTLNLYAKNFPIDVDNLIKWMGWTGVATNTINWASMGSIPSDLLRTPEFTLRDLLLHSLDIFAVPSRTFFEKLSYFAADEDQKTRLFEFSQSQFTDEYYDYASRPRRSILEVLQEFDTVRIPAHAVLDIFPVIRPRQYSIANWPQVGGGAGLAEDTVEIEIVVALVKYRTVLRRVRRGLVSRYLEDLPEGTEMYVSHTASSSRIYGPENARRPLVCVATGTGIAPIRSLVQERRSHVENGGTETETEMSTPTIDLYFGCRNRESDFHFGGEWQHLEEHGVISLHTAFSRDAQTKVYVQDILQTHKKQLAAWVKSDAIFFVCGGSRRMADSVKRLVKDAMVEYKEVEAEQHVDAAFRGVSWIEEIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLS7</accession>
    <name>A0ABR3ZLS7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sphinganine kinase lcb4</fullName>
            <ecNumber evidence="7">2.7.1.91</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">LCB4</name>
        <name evidence="7" type="ORF">Cpir12675_000373</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.91" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008481">
        <property type="term" value="F:sphingosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055916">
        <property type="entry name" value="DUF7493"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050187">
        <property type="entry name" value="Lipid_Phosphate_FormReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045540">
        <property type="entry name" value="YegS/DAGK_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358:SF31">
        <property type="entry name" value="ACYLGLYCEROL KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358">
        <property type="entry name" value="SPHINGOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24321">
        <property type="entry name" value="DUF7493"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19279">
        <property type="entry name" value="YegS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="6">
        <location>
            <begin position="130"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="337"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="340"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="526" mass="57144" checksum="ECEBB157D5A41DEF" modified="2025-10-08" version="1">MRSLSIDERVPFMAANEETEPTAGSLGFVPELKLSGKRNLVLRDKTILLKQTSIQRSLCLPSKPSCAEISFYNILWVESNGLNLSIDYVEGTQSSELTVCKLEGQVIDSTPKDLKEWATVAMDRAYGTSQRKKRALVLVNPRSGPGGGEKKWATKSRPIFEAARMPMDIIATSHGGQATDICEKMDIDNFDIVVGCAGDGMPYEIFNGLGKRADASRALSKIAVAHIPCGSGNGMSVNLYGTHRPSVAALAIVKGITTPLDLTSVIQGESRLLSFMSQNVGMIAECDLATEHLRWMGDNRFVVGFLQRVMSGVAYPCDIAAKVEISGKNAIKSHYHREQSQAGLSAVSTGKKTGHEDTSSGGTIEEGLPELRYGTLNSSILSDWELLRSDSLGCLYVGNMAFMDRTNNFFPAACPNDGFLDMITVNSDIGTLQWVKLMDAVEKGTLLDNANVTYKKISAFRVTPRDQDDGYISIDGERIPFGPFQCEVHRGLGRVISKNGTFEGTGPGSAHEDWDEAVSMAEQMQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM18</accession>
    <name>A0ABR3ZM18_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_000266</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051052">
        <property type="entry name" value="Diverse_substrate_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942">
        <property type="entry name" value="METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942:SF4">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="4">
        <location>
            <begin position="51"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1901758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="286" mass="31580" checksum="7425C5D4221D8933" modified="2025-10-08" version="1">MTEAKIHSSATVGFTDGKSYDDFRPSYVEEAVSGLLAGLNLIGAEGAAVVEVAAGTGKFTESLAHRPEAFRITAIEPVEGMREQLDKKKLPNVVSFAGTANEIKAETGSTDAVIAAQAYHWFAKRDAMCEFARVLKPDGVLGVIWNVEDYNKPAEWPAVTQWEEQLNKHVLALPPDGQDRFRQLSWRNGFSPAENTSSDGVQLFRTPYNEAQSAVWSTRLTPEELLDRISTLSQVVALEGLERQEWIQKYWAVLKTAETAQDGTVEVHGKTFYAWSQKMPGQGSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZME2</accession>
    <name>A0ABR3ZME2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dolichol kinase</fullName>
            <ecNumber evidence="3">2.7.1.108</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SEC59</name>
        <name evidence="12" type="ORF">Cpir12675_000449</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the polyprenol kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.108" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032974">
        <property type="entry name" value="Polypren_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13205:SF15">
        <property type="entry name" value="DOLICHOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13205">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 15-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="261"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="300"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="450"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="549"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="590"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="644"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="685"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="725"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="369"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="369"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1901580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="799" mass="87798" checksum="D368811BDFFBEB13" modified="2025-10-08" version="1">MPFEASTVSDSGTEADGEYFLRGLPAPKACLHKGLRGEEEPLSGVSTPLLAPPAQRIWKPECMIEDSDVQIMKKKKRRSRILARRAAELGVVVVLTGVVIANEDVAAMIKPLTRELAQFGALYTLMLCVFPLRVIMLRTSPYSKSTLGLSSITIPPDFDPAPLLYPPVLTLLTSFLISSDKSQLIAPNIVLAISTIPRHLVPFAHYSTSDSSSSSVHWLLSLLPLLTSTSSASKLTIDQLFTYKSPEILSYLYPLHQSFCVVLYSLTTSSLLPAELELLSVALINILLFAESPQIKILRALIWVGGFLVLLSTGNTILKGIALARVPKWRFRRDRRRIREPPIVRPLRLLWNPFCLKRELLGLGSSKNSITSNTEETSDSSSGNDCNDDSLEAMQSSNKTRVLAKSRKKTERSSENRPQVIPTKRRRRTLSVSLKPLLKLTPKQATARKWLYAGYVYACIMTIIIFPVRLAISRDALNGHEAIGWAMGYLFGDVGYFRWQVVSYNLNDWIVLPPRIESLNKAVCCGSGWVQNIRLSFVGVANTRLLLTAYWLLILVIGLLVVFRLSAIYEVDTRRKVFHFMMVAMMLPSIFVDACFCAIALSFTLAIFLLLDLLRASQLPPLSKPIATFLAPYVDGRDFKGPVVVSHIFLLIGCAMPLWLSLAAQSRAVSDVQGWPQGWELPARHVSMVAGVVCVGLGDAAASLVGRRYGRHKWYWGGGKSLEGSIAFALAVCAGLMAASAWMRIGGWPVAQEVGVSRALGNSLGCGTLASLTEAVLTGGNDNVIVPVVLWMCVKSIGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMQ0</accession>
    <name>A0ABR3ZMQ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome production factor 2 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Ribosome biogenesis protein RPF2 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RPF2</name>
        <name evidence="7" type="ORF">Cpir12675_000257</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
            <location evidence="1 4">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the RPF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039770">
        <property type="entry name" value="Rpf2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12728">
        <property type="entry name" value="BRIX DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12728:SF0">
        <property type="entry name" value="RIBOSOME PRODUCTION FACTOR 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Brix" evidence="6">
        <location>
            <begin position="30"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="287"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="313"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="334" mass="38039" checksum="9FBFDAFCE2901599" modified="2025-10-08" version="1">MSLLREIKPRNARSKRALEKREPKAFENPKTALFLRGTSCSQIVQDAMNDLYALRQPFAKKFSKKNAVHPFEDASSLEFFANKNDASIMVFGSSNKKRPHTLTFVRMFNYHVLDMLELLLDADSFRTLTQFKNKKFSVGLRPMVVFAGSAFENPVDRVYTQAKSIFTDFFAARDSADKIDVEGLQYVIQIAAEEPTQNEGADGQVRTSCIFIRAYTLRTIRSGQKLPRVEVEEIGPRMNLRIGRVREAEEAVMKEAMKKARTTEERVKKNISTDEMGDKIGRIHLGRQDLGQLQTRKMKGLKRSRDQTAPEADMMDIDDVVSDDDDAPKKKTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNH6</accession>
    <name>A0ABR3ZNH6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L36</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpl36</name>
        <name evidence="6" type="ORF">Cpir12675_000216</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1760">
        <property type="entry name" value="60S ribosomal protein L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000509">
        <property type="entry name" value="Ribosomal_eL36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038097">
        <property type="entry name" value="Ribosomal_eL36_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10114">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01158">
        <property type="entry name" value="Ribosomal_L36e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01190">
        <property type="entry name" value="RIBOSOMAL_L36E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1901709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="106" mass="12055" checksum="1847D40B59505325" modified="2025-10-08" version="1">MSKEASIRTGLATGLNHGHKTTPRVQKARISRTKGHLSKRTAFVRDIVKEVSGLAPYERRVIELLRNSKDKRARKLAKRRLGTFGRAKKKVDEMTRVIAEARRLGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPL2</accession>
    <name>A0ABR3ZPL2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Meiotic recombination protein DMC1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000209</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031349">
        <property type="entry name" value="Tfb6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37781:SF1">
        <property type="entry name" value="ADR380WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37781">
        <property type="entry name" value="TFIIH COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17110">
        <property type="entry name" value="TFB6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="323" mass="36023" checksum="99A11EBDA01EB80A" modified="2025-10-08" version="1">MTDPPQREAYDRDTAMTGIHPSPLGTSPSSLHSSQTPADEIHHNNTPLPTEFPVLQGLPAQRHQPLREGFQQASFARRFVHACLVKVQQRNLRRLIDLLGTTTPQTNLQIAYTSFAQVCEDVDQIVNFLWYTGSPFLQIPYMFELIVEFVELAFAMDPAPIPTLIVLRKFDHIFASLARQKDVVTDEAVVGVDSYSMTQTDIVRLQAIVSDVRARMWEKLDKTAAVEKTLKDGDETGGRDSDDYDGCEDDDDNDDDDLECSFEDKFTETADEPLPGATDEQASTSVDGSDWRPPRTTTELGVAVAQVFEQTLVVVNEKLGDSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPT9</accession>
    <name>A0ABR3ZPT9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">RuvB-like helicase</fullName>
            <ecNumber evidence="13">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">RVB2</name>
        <name evidence="15" type="ORF">Cpir12675_000087</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the RuvB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="13"/>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.360">
        <property type="entry name" value="RuvB-like helicase, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027238">
        <property type="entry name" value="RuvB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041048">
        <property type="entry name" value="RuvB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042487">
        <property type="entry name" value="RuvBL1/2_DNA/RNA_bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010339">
        <property type="entry name" value="TIP49_P-loop"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11093">
        <property type="entry name" value="RUVB-RELATED REPTIN AND PONTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06068">
        <property type="entry name" value="TIP49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17856">
        <property type="entry name" value="TIP49_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0010">Activator</keyword>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 13" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4 13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 13" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 13 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0804">Transcription</keyword>
    <keyword evidence="13" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="68"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1902187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="470" mass="51211" checksum="9E5C1530CEA33F81" modified="2025-10-08" version="1">MSAPVVTVGETKDLRGLNLIAAHSHIRGLGVDSTTLEPKKQSQGLVGQEKARKAAAVVLKMIQEGKIAGRACLIAGPPSTGKTAIAMGLAQSLGVDVPFTSLAASEIFSLEMSKTEALTQAFRKSIGVRIKEENEIMEGEVVEIQIDRSVTGTAKQGKLTIKTTDMEAVYDMGSKMIDAMTKERVVAGDIISIDKSSGKITKLGRSFARSRDYDAMGADTKFLQTPDGELQKRKEVIHTVSLHDIDCINSRTQGFLSLFSGDTGEIRSEIRDQINTKVGEWKEEGKAEIVPGVLFIDEVHMLDIECFSYINRALEGDLAPVVIMASNRGNSRIRGTDYRSPHGLPLDFLDRVAIIHTHTYNGDEIKEILSIRATEEEVDVSPDALALLTKIGQEAGLRYASNLITTSHLVATKRRAKAVDVDDVKRSFQLFYDPVRSAKFVTESEKRLIGDDGAVDFTATNGHGETMDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPY7</accession>
    <name>A0ABR3ZPY7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pisatin demethylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_000012</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1902115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="540" mass="60490" checksum="8B6BE1FB4D8595E3" modified="2025-10-08" version="1">MLTSAILSFLAAHYLPIAAVLLALHLIRNYFRHGLHRYPGPWLARLTDFWRLWDVYNQAPHKTHLALHARHGDVVRLGPNVLSFSSPAAVKDIYGLNKGFIKSDFYIVQQSIVQGRRLASLFSTTSNAFHATFRRCVSSAFAMSALVGYEPFVDNTTRLFLDRTEELFAQKPNSDAPESCDLPRWLQFYAFDVIGEITYSKRHGFIERNEDVDGIVGYLARLFVYVAPIGQMPFLDLLFLKNPLYLKLSQWGLIDSTFPVAQFARTRLAERVPNLSSSPDILKPTSSPSKPDLLTKFLNAHAAHPSVMTPTLVQTMAVSMAFAGSETTAITLSAIFYMLLRHPRALDALRDEIDAAASRSHFADRTTGLTTFAEAQRLPYLGAVIQEAFRVHPAAGLPLERVTPAGGAVIDGHHVPGGTIVGVSAWVLHQRSEIFGADADKFRPERWLVDPTADLVAEEKRLKTMNGFMLQFGMGSRTCIGKNISLLEIYKLVPSMLRRFDITLANPKEEWKLINAWFVKVENFNVHLKKRELVQPGTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQE2</accession>
    <name>A0ABR3ZQE2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cyclin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">CLG1</name>
        <name evidence="1" type="ORF">Cpir12675_000144</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF27">
        <property type="entry name" value="PHO85 CYCLIN CLG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1902038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="338" mass="37703" checksum="40FF23978A36A312" modified="2025-10-08" version="1">MPGGVCAVLDYEVEQMTDYVAEMAVRVVMPDSPVSDRFRKFVTQILTATRLPSTTILLGMNYLAKRINTIKANPQIHGPYKASEGEVWRYLTVALLLASKFLDDNTFQNRSWSEVTSIPVSELNTLEFEWLAACHWQLYVNLDKTKDYQAWLSDWHSWLASRKSAEEEARAAERAMAMARKLSDLPTIQTAFPSHAQGVTSPLSSYSSGRGSLDIGRYSTKSDAAHYDWSSTSYHNHNAPITPPDSGYATPEHVVSACTVNSRYNEWFDQQLQYNGSYHHSSQGPNSGYPSRTSNYSGRYPYSPWEPSSGNCTCCTGCHVADKTYLGGAHVYSQAVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRK2</accession>
    <name>A0ABR3ZRK2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000017</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="450"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="476"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="603" mass="65947" checksum="0F1C2FE5F0374CCB" modified="2025-10-08" version="1">MTSTRPPPPALSESSSVTRRLPLFRFSLPPPRQQPVGIIHEETMENSIPASQLPDSQADARKRSNRRSLAEVPVYTQTPIARKPVRPRPVSDYIPRQSHVVRFQEPDAQAPKVGDNVSLPDEENYHVRNYLAQPVPTPSQPPTVISSEDDDGTYSEISDNSSTFTSSIAGGSRRRSKRLSKTGSRFIVAQPPPKVVKKSRRFIQMRPQLLLQIQLVTETRPKPMFDVLPSTFVSGSTFAAPRLARKFPRLFRVSGNLGPNDLVLARSEDYDIDENSDATEERLDRRDLIAVFSPVLETEKTDIVLADGTVWSATALTNGSYDFVHDSADGVLTRARWAKRRVSHGPATVPENNLGSDEPASYKFTFSILDPATRRHPVMATVTPTWLEIQDFCYLPDQPRDSAHLTPRSSVANKGAANVFASNDRRFLPIDNETRAFIAISSVWVSLQQKGITGATPPRRSSIRRSLSNYDKPQTPASSASSGASSPSQIPVPATASAMPTSSICSTISQKRASLPAAPQDQGNAPRRSMSTGAAFMQRRVAAATASSSVGAGDLPHDPASILRSATFVDGSSVMSGSMGREHKKGIFSSLKRVFSRRKPSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YAL1</accession>
    <name>A0ABR3YAL1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006978</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000477">
        <property type="protein sequence ID" value="KAL1885351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1885351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="114" mass="12236" checksum="858C8589BDB6F195" modified="2025-10-08" version="1">MLALNLTQRYFTSVAGLVSEKAVVTIVWPHLAMVATMDAKVASLSAAPDAYCAPGYTGMIEMAMDEGGWEAALELRRQRGGVLPPNAEANKGGNAGRNRPRSRSPRPVQHHHIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YF85</accession>
    <name>A0ABR3YF85_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_006830</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000387">
        <property type="protein sequence ID" value="KAL1886941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43963">
        <property type="entry name" value="CARBONYL REDUCTASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43963:SF6">
        <property type="entry name" value="CHAIN DEHYDROGENASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1886941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="265" mass="29047" checksum="3F4875D2BE4C87A0" modified="2025-10-08" version="1">MTSSQHSTVGQGMMALLSDPEIVASKALHIHGGKVTLNVEVVDPSDMASIDRFTRTINERHHRELDFIVNSMGLMLNSFGEQMEKINKVQRATNTPFLPDSASVQATIAHDIDGLLAICNSFSPHMRPNTGHIILPGHEAESFSYFPPTCASLFLNSRTLQDIQSIMQTFAYAAMRGVVIDEGWVPSARSMSKAATTTLARVLALENEFQRNKVLFSAASTRQPIETRITRFPFEEMAQMAVSLVLSGCGGQSGGLWDNSVATFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFG1</accession>
    <name>A0ABR3YFG1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cdc25 phosphatase Ibp1</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ibp1</name>
        <name evidence="2" type="ORF">Cpir12675_006736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000362">
        <property type="protein sequence ID" value="KAL1887035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10828:SF38">
        <property type="entry name" value="ARSENICAL-RESISTANCE PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10828">
        <property type="entry name" value="M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="27"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="140" mass="15411" checksum="AAFB775354B201F0" modified="2025-10-08" version="1">MATIASINRISASRLADMIRTYEGQLGDAPFAIVDVRDTDYIGGHIKGCTNIPSHSFDIMLPGLIQTLANKPTIVFHCALSQQRGPAAALKFLRELQRLGKASNHQVMVLEGGFTSWQELYGADDALTEDYDSGLWRNGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFL9</accession>
    <name>A0ABR3YFL9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uracil phosphoribosyltransferase, synthesizes UMP from uracil</fullName>
            <ecNumber evidence="2">2.4.2.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FUR1</name>
        <name evidence="2" type="ORF">Cpir12675_006820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.9" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000384">
        <property type="protein sequence ID" value="KAL1886953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004845">
        <property type="term" value="F:uracil phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001097">
        <property type="entry name" value="PRK00129.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14681">
        <property type="entry name" value="UPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="1">
        <location>
            <begin position="40"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1886953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="243" mass="27135" checksum="C2E5C931F6149232" modified="2025-10-08" version="1">MESESSAPVVPVSYSNNENFQNPSATVSKTVPFDNVHVLPQTPQLIALLTVIRNKDTQRADFVFYSNRIIRLLVEEGLNHLPVVSHDVTTPVGRTYSGLMFQGKICGVSIMRAGEAMEQGLRDCCRSVRIGKILIQRDEETAEPKLFYDKLPDDINKRWVLLLDPMFATGGSAIMAVEVLKSRGVPEERILFLNLIASPKGVENFATKFPKLRVVTAFIDEGLDEKNYIVPGLGDFGDRFYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFU7</accession>
    <name>A0ABR3YFU7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein HGH1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">HGH1</name>
        <name evidence="5" type="ORF">Cpir12675_006660</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HGH1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000344">
        <property type="protein sequence ID" value="KAL1887176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039717">
        <property type="entry name" value="Hgh1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007206">
        <property type="entry name" value="Protein_HGH1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007205">
        <property type="entry name" value="Protein_HGH1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13387">
        <property type="entry name" value="PROTEIN HGH1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13387:SF9">
        <property type="entry name" value="PROTEIN HGH1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04063">
        <property type="entry name" value="DUF383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04064">
        <property type="entry name" value="DUF384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein HGH1 N-terminal" evidence="3">
        <location>
            <begin position="96"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Protein HGH1 C-terminal" evidence="4">
        <location>
            <begin position="283"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="359" mass="40717" checksum="6B8A3368D83009C3" modified="2025-10-08" version="1">MPTELEELVGFISHPNPQIRQVAVENLVPFSLSQPEIFKANEYQSLKFLKILTRDKPAISEHAVTILVNLSGEEEVLKNLATDEAFVNSVLQRMVMAGEPNADSLSMLLANLTKWDGMKSILTKKQPQVDKLSASDLVLNQLMDAFVKGSSSEFNKKANYDYLSYVFADLSKHEGIRKFFLTKQDYDGEYPLNKMKVFTEHSSEIRRKGVASTIKNAAFEVNAHPLFIDEDEINLLPYVLLPITGNEEYDAEDMMEMIPDLQLLPPDKSRDSDPTIIQTHVETLMLLTTTRSIRGHLRAINVYATIRETHARVDNVDVQEACDRLVQVLKRDDPDEDIEGKETKVVEIEEDDEEAMTEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFV8</accession>
    <name>A0ABR3YFV8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006852</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000393">
        <property type="protein sequence ID" value="KAL1886925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="507"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="918"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1015"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="447"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="507"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="562"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="605"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="629"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="674"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="750"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="782"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="813"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="940"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="969"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1038"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1105"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1163"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1886925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1191" mass="128114" checksum="61180A8861792FEB" modified="2025-10-08" version="1" fragment="single">PLRNINGSIKSKYSKTLLQSSPSSSLSFSSSLRQCESLSQPQPLYQPQETRKSSRQSRKAKGRAAAIGATGAPAADTAPTTDAAKLSACVSAASPSAIGSRYSSALSSLPPAAEDSPQPLGVVDGFWKDHRLSQRDANQCHREALASAPTSSSALASAPAPEKRAGTFSSSDSPISSMSSSSNPLSAPYTTWEAYVDDWTLQPESRIPEVEEKEEDEDVENDADGVDDEGLVEDEDGAVEPMPGSQQLTSAVATSRVASSDEADEASDNRLFLFRKLPDITDIVNTLQNHDDMDYDQLAHSIDAVNKILYQYQNEFVATTAVVDDWENAQRRATDDVNAEKLLVPKEFLLKGYSTKSMTAKESEIHAVRMMDRLMADVYFFRHDPHISKVGRQDPLDQPHEAAPNHCDVRRSLRNDPNKTAKGTDHADPNIITGKRMRKPREMFDGQPNSRSATPALQTVSKRSTRSKRGEDELLDSNPGANSVSGSFNSNASFSGLGATAAALGLSEAHQQSSTPSTPVPAPASAPSLSTPTKKGKPDSGPNPRKRRRIKNEEPAPAVEEPASEYEELEREEEKVPEPEPAPEPVEEEEPPRKRRVRRTKVQIAADKAAAEAAQAQAQAEAEAEAESEATAVDAASSTVPPSAATSDFEADDEPAKKRIVSLMVPNLHVVRGSSTTSSKTTTPASTGKRGRKGKSSGKDAPTPPVNGSGRRKASSTIQPSPPTFTPNDNIAGPPSGPVVFPGAQPPPNHNGQIMWNSNPNKHNKLEGGSGRGRGRGGRRSTGGASHASQNSPLAQSQAPQPAQSPIDSSHMQQLPPHSQSQVPPPHLMHMQNQPMYDNKQPPLSHMPTIIAHYPPLQHQHQHQHQHQLPPHSMAPQSGNGGSSSHPASHHHSHSQTPPYGGSHIQYAPKTQFIQHSHTMPPQHSHVPMHGHSHPPLGHSHGHSHSHSHGHNNSHGMPPPPPVAASAGIPTSGSQINGSVGPDGDNRVRIKMVKPNQKPINLDNVVMGSKEYAQMTKSEKMSHSMKNRWKSGSMQGAVDKRKATLARKKQDRDPVPGNSSNNSNSSRAVNGTPAAHPTDSGSPTQSAHPIAYANPNSVAPMSLYPHHSQPPHMHSHSQIPPPPPQQRGQHPHGIFITQPPQPGYPQQGQQKQHVNLPPPPMGPQSHQQPHPSQQQEQMNTLNISHYPPSQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGL6</accession>
    <name>A0ABR3YGL6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Growth hormone-inducible transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_006601</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000332">
        <property type="protein sequence ID" value="KAL1887298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006214">
        <property type="entry name" value="Bax_inhibitor_1-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291">
        <property type="entry name" value="BAX INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291:SF112">
        <property type="entry name" value="GROWTH HORMONE-INDUCIBLE TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01027">
        <property type="entry name" value="Bax1-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="232"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="270"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="336" mass="36055" checksum="206167A8B4950C7E" modified="2025-10-08" version="1">MAFNLVRQAPAAVAKSPALRTLSMSTRAFASSAKPYSTFFTSRAIPSMARSSGRPGARFYNQQSYQQAAPVQGNTVRKLLVGGAIFGGTLTAINLVFNRETRTDGGIPAFERNYLNDTFLHTGLGVGIIGLSAHQMIRSGFVYRLMVTNPWLVGIGGLALSFGTMIGTRSISPDNYIPKYAMWTAFNATQAAMIAPMLAFMPGALIARAGLYTVAMMGSLSVVGATAKQDKYLYIGGPLLAGAAIVAASGLAPLVIPATAIRTLAFTENLWLYGGLAVFGGFTLYDVQKVLYHARLAERGAMSRDPVNESISLELDFINIFIRMAQILAMQGQRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH56</accession>
    <name>A0ABR3YH56_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">P-type Na(+) transporter</fullName>
            <ecNumber evidence="19">7.2.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="primary">ENA2</name>
        <name evidence="25" type="ORF">Cpir12675_006509</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="25 26">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>K(+)(in) + ATP + H2O = K(+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:75815"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>Na(+)(in) + ATP + H2O = Na(+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.3"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="21">
            <dbReference type="Rhea" id="RHEA:14634"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="18">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IID subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.3" evidence="19"/>
    <dbReference type="EMBL" id="JAWDJO010000312">
        <property type="protein sequence ID" value="KAL1887523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02086">
        <property type="entry name" value="P-type_ATPase_Na_ENA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006414">
        <property type="entry name" value="P-type_ATPase_IID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01523">
        <property type="entry name" value="ATPase-IID_K-Na"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="16 23" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0915">Sodium</keyword>
    <keyword evidence="17" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="12" id="KW-1278">Translocase</keyword>
    <keyword evidence="6 23" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 23" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="328"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="872"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="919"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="970"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="1003"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="24">
        <location>
            <begin position="25"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00035017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00035029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00049499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="KAL1887523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1108" mass="119941" checksum="F3294FF1C7410C13" modified="2025-10-08" version="1">MGRPPAPTPAETHVSGQSNIPLSRPAHALTASAVAAELGCNTLTGLDPAMAARRLDEIGPNDLGDAPGVQPLRIVIAQIANAMTMVLIMAMAVSFGIRSWIEGGVVAGVIGLNIVVGFFQEYSAEKTMDSLRSLSSPTGTVIRNGESKVVPSSEIVPGDLITVKMGDTIPADMRLVEAVNLETDEALLTGESLPVSKNAALQFNDSTGPGDRLNVAYSSSTVTKGRATGVVFATSVYTEVGAIAAALRKQDSHSRQPKRNSQGKVTPFRYLEAYTLTTTDAIGRFLGVNVGTPLQRKLSKLAVLLFGIAVVCALIVLGANKFDASQEVIIYAVATGLSMIPASLVVVLTITMAAGTKRMVQRNVIVRNLRSLEALGAVTDICSDKTGTLTQGKMVARGAWIPAFGTCTVDPSSAPFDPSEGLLRYVPAQPRQANLTSGSPVGSALSPSAFLQSGKEPLIDFLTVASLANLATIVKKDDAWHAHGDPTEIAIQVFASRFDYNRLRFLHGDNPEWSEVSELPFDSDVKRMSVVVRHNASGELFALTKGAVERVIEACTGYVASDNGQVVPLTENFKAEILRNMETFAGMGLRVLAFASKPYPFAVENDAAVPRENVESNLVFRGLIGLYDPPRAESAPAVRQCHEAGISVHMLTGDHPETAKAIAMEVGILPAAMGRVAADIAKIMVMTATQFDSLTDDDIDQLPVLPLVIARCAPATKVRMIEALHRRNRFVAMTGDGVNDSPSLRRADVGIAMGQTGSDVAKDASDIVLADDNFASIVAAIEEGRRIFDNIQKFVLHVLAENIAQAGTLLVGLAFKDGRGLSVFPLAPVEIVWIIMATSGMPDMGLGFEHAVPDIMRRPPQSLSTGIFTMEFLVDMVFYGLWITALCLGSFILVVFGFGDGDLGFQCNDSYNDTCDVVFRGRATTFACLTWFALFLAWEMVDMRRSFFAAPSFSIDGLKHWARTLWRNQFLFWAIIGGFATLFPLLYIPVINTKVFKHKGISWEWIIVFIATGLFFVGVESWKWAKRVFFRRQAKKTQGAVWKNLDIEQRAFAEFFEQRKEEKINPTGTDSFKLNEKQDIDLAKTEDLATTIPDKAEQEQAIADTGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHQ9</accession>
    <name>A0ABR3YHQ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Conserved oligomeric Golgi complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">COG5</name>
        <name evidence="7" type="ORF">Cpir12675_006407</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000295">
        <property type="protein sequence ID" value="KAL1887821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019465">
        <property type="entry name" value="Cog5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048485">
        <property type="entry name" value="COG5_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049176">
        <property type="entry name" value="COG5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13228">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13228:SF3">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20649">
        <property type="entry name" value="COG5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10392">
        <property type="entry name" value="COG5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 5 N-terminal" evidence="5">
        <location>
            <begin position="13"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 5 helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF20649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1887821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="437" mass="49651" checksum="B9E8B3E5843CF2C9" modified="2025-10-08" version="1">MNNNDYSYVDYRAFLDPTFQPPAFIRDLVQETSSLDDQPIDFSTPLSRILFDIQEINSNIDSVTTGSAEPLLNHTQGQNNASQSLTDGLDALSDALNRSHLHLEHQVGITYDFANMTRYVARRVTSTHGLLTPLTNFCKLSRQLEIHCLDFLPPGHSEPQNYPSLVRCAEVIISSKSTIDRAFLGVEARGLERLRVVNELQDAVISPISDVVLQQSNRIIREFSVPESETFAQSEASKLRLASSLHALYFMSYFDFIRRIHLFKPILLYQSVHAYIRNAVDSSTEAFVDFLGQLTLPHYGISRIIKHGRNIMALEHVMSTCWPGHHEVLPDVPTASSYLQTFQTYIGCQSLIRLFWHVLTDKLRQKVVDIIDLDSPQAQTLQNRTDLIVNAIREFIVNGSRMPESWVTVTEPQREDQLQMLPEMAHMVTAIVGVLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIZ3</accession>
    <name>A0ABR3YIZ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7053 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006371</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000289">
        <property type="protein sequence ID" value="KAL1887925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055481">
        <property type="entry name" value="DUF7053"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38117">
        <property type="entry name" value="NACHT AND WD40 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38117:SF2">
        <property type="entry name" value="NACHT AND WD40 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23155">
        <property type="entry name" value="DUF7053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7053" evidence="2">
        <location>
            <begin position="2"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="500"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="311"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="504"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="525"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="572"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="584"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="724" mass="79464" checksum="D001ACE240EA18F5" modified="2025-10-08" version="1">MSKRTVFTAIVPVPPGISREIVLAFLHSPEEMVRTSPLVVSHKPIRVPDNCPADERDCTWFQLRGKGWHLPGSNKMTGDSSYTVALQSTPIGCTVHLYAPMNVDIRSTWMLGGRLPGEYDRRSDGYSAPEGAPASGLYLREDVEIRCHSLMTGYIKKSIKKSHNSIGDRLRQRARRHSSKPFLGSSTNGPVDMPHFSSEPSPVNYNYKMEMYQPMLSFGQKPLDSNQVKPRPEARSTAPSPDRTPVRTFTTETMESYTSSVVSPVSESEGVRESIIISALSPPPPRTPRSEGGCQFPQLDVTLDTPSTVMSPASSSHHRSISAPSLNKNYVRPPSFSTSRAAKSNTPKALDLKAKDLGQDEPEQKQTPLFSNNLYLPATRQRSRSHGQGQPSSLMPAPERRPSRPVSTPFISSNQPWIAEDPLDFFGGDGAFGRRSPKPYLAPLIIPRNPKSPPPVLVGQTKPAAVEPRFVAGLRLQQKLAQVGPRNNASLAEQGAQMRFAQKGPAAGPAAPSRRPAIVRHSRGPSRETAVDCSKRPQAKEHTLPPPISLRQGGIQREFSFDTTPDEAVAPKNERLWLRRPESPDSTTPTLRNSLSTTASSQLPEAGDRPLEQQLTQYAVTHRLPFHSPTDVEDTELEPSPGAVAAIAAVREMEAKENALQAYPYPRPLRIEKWVASISQAEAPGAQQKRASQLRPAVSIVHKYPNAHKQNYSDLAAANPFADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKS6</accession>
    <name>A0ABR3YKS6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_005987</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000239">
        <property type="protein sequence ID" value="KAL1888924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1888924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="94" mass="11052" checksum="AA6F6C4187FA4F33" modified="2025-10-08" version="1">MLLKKTFEDVVNRVTIPHPDDNAALFKYHAERATAASITQTYDYMIRTRLEYGFVYNGESTVFLNIDWSHPETLLYHLAEPEPEMDEEFEATRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL30</accession>
    <name>A0ABR3YL30_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_006112</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000254">
        <property type="protein sequence ID" value="KAL1888577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1888577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="94" mass="10121" checksum="A987410EFF48B44C" modified="2025-10-08" version="1">MKSDSLYHAVKSLVDNHGINITHILSYTGPGSIDNSGSSISTRVGARSWTTERFLFSYVNGQLVDMESEYLGGALTGVTPESARNSLAVPPWGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLK4</accession>
    <name>A0ABR3YLK4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peptide hydrolase</fullName>
            <ecNumber evidence="9">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">APE3</name>
        <name evidence="12" type="ORF">Cpir12675_005983</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M28 family. M28A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000239">
        <property type="protein sequence ID" value="KAL1888920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03876">
        <property type="entry name" value="M28_SGAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02130">
        <property type="entry name" value="PA_ScAPY_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041756">
        <property type="entry name" value="M28_SGAP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF17">
        <property type="entry name" value="AMINOPEPTIDASE Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="7 9 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0732">Signal</keyword>
    <keyword evidence="8 9" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045003479" description="Peptide hydrolase" evidence="9">
        <location>
            <begin position="19"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="10">
        <location>
            <begin position="154"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="11">
        <location>
            <begin position="266"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1888920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="515" mass="54663" checksum="DB560179372CD600" modified="2025-10-08" version="1">MKLYAATAAMAMVGSASAVAVGSQVPLKATTSSAVSAPGSLMAGSRSTLTSKALQDSIKGAPLMARASEFYSIAKLSEKKHGHPTRVIGSPGHNATLEYIKSELAKQGDYYSVWTQDFEAFAGDVHSSYLIINHVKLNGTAMSLSPSTKDTKAVSGKIVPTSGTGCKAEDYPSQVKGSIAFIKRGECAFGTKSELAGRAGAIAAVVYNTEPGDLHGTLGVPTPHHIATLGLSQEEAQPILEQLGRGKWVSGIAMVNSTVELISTTNILAQTTEGDPDNCVMLGAHSDSVAEGPGINDDGSGSMSLLEIAKQLSSFSVRNCVRFAWWAGEEEGLLGSDYYVATLPKKENSKIRVFMDYDMLASPNFAYQVYDANNYANPAGSGELKELYIDWYNEHGLNYTMIPFDGRSDYDGFIRNGIPGGGIATGAEGIKTEAEVSMFGGSAGEWYDPCYHQLCDDVGNVNETAWVLNTQLVAHSVATYALSFDGFPERVLTSDAKILASEGYTPKFHGGKLAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLZ6</accession>
    <name>A0ABR3YLZ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SGNH hydrolase-type esterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005884</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000226">
        <property type="protein sequence ID" value="KAL1889218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00229">
        <property type="entry name" value="SGNH_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051532">
        <property type="entry name" value="Ester_Hydrolysis_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383:SF19">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383">
        <property type="entry name" value="THIOESTERASE 1/PROTEASE 1/LYSOPHOSPHOLIPASE L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="2">
        <location>
            <begin position="33"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="232"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="259"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="462" mass="50075" checksum="986E74E2B076421C" modified="2025-10-08" version="1">MFTTLPGTAPRRHGQADLLSFPCPPHKSFRVLCLGDSLTSGYFDLGAGAHPYSGNLYLMLGDEFPRLDVSVDTDGQPDDFVVGGMFSSRMNLRWSEVTYDWTIVLGGTSDIAHGTSPQDIYKSLQEIWAVPMSKGKNVLALTIPEAQISTADEVQRRDEVNRLIMQHRAEGFYAFDLHTRIPYHSLDDQSRELYWNDGLHLTEDGYDWMGGFIADELIRILKSLQARDRENASAPASSLSVPSSPQTLTPTRQCYIRPSSSVRSTASVSANDKNTRKPGDIHAAIASTSSLPNTQAIPPTHGDPCLTVSAVEANSSSSFSSPASSSNGSASPTYLLGSTNFPFPDTSSRMSDGDGHIFLSSPSPTRPSVRGGNLRHQNTSQNHTFGNSGNANARSHSHGITRSGAATSIGRSHAHNGGITAVRRSKRLAKRSWDMAVAEDEPGVAARRLDSGYIMVHRKDIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM42</accession>
    <name>A0ABR3YM42_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005804</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000217">
        <property type="protein sequence ID" value="KAL1889404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00083">
        <property type="entry name" value="bHLH_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46266">
        <property type="entry name" value="TRANSCRIPTION FACTOR TT8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46266:SF4">
        <property type="entry name" value="TRANSCRIPTION FACTOR TT8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="2">
        <location>
            <begin position="187"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="411"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="435" mass="46673" checksum="E056BFCA43B5AD7E" modified="2025-10-08" version="1">MPHPNLPLTPSSTEIRGKYDASHIACLQLAFELPPPAIAQAGPRKHSIGLMATYTYPVQPAEVVKSRKRVPPPTSQLYTTTVTAKSAFTLPPPPTLTRKIIQMKPKPRGQSSSKQTKALSRAASKGTSTDLESVVTPIETTAACTSSGASPDGTSGAAVELTSASSAPQPKKKQPAIANAAAGRKQARKTAHSLIERRRRSKMNEEFAVLKDMIPACTGEMHKLAILQASIEYVRYLENCVSQLKAQHQANTGAFPAPPPPFEAFDLSPQRCHEDEDEDNNDDNDNDNDNEAGTSTGSVVHFITGPVNDIDMADSYSSTASISTTDYQRGSYVSSTISPSFEPQQYPMTPSYTGLPSLALTSLTMPTYTTLPSSATTTPALHSQRDGRDLDHEATAALLMLTNDRRGDVEMRYGSGKHQKGGSGRGMSVRDLLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMG3</accession>
    <name>A0ABR3YMG3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protection of telomeres protein 1 ssDNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_005945</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the telombin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000234">
        <property type="protein sequence ID" value="KAL1889027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028389">
        <property type="entry name" value="POT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032042">
        <property type="entry name" value="POT1PC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14513">
        <property type="entry name" value="PROTECTION OF TELOMERES 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14513:SF0">
        <property type="entry name" value="PROTECTION OF TELOMERES PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16686">
        <property type="entry name" value="POT1PC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0779">Telomere</keyword>
    <feature type="domain" description="Protection of telomeres protein 1 ssDNA-binding" evidence="9">
        <location>
            <begin position="174"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="332"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="574"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="332"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="369"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="585"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="600"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1889027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="663" mass="75030" checksum="F215ACBC8587B622" modified="2025-10-08" version="1">MQAPLHSLNDICSDLNLLGRLVSTVGVVVEYRGNTRTRNGEWKSMLRLRDNNGQELEFHLFHRDEKAMPQKSYIGCGAIIISAKVQRRDGQSLLSSSSTEITYYDPLDINSLSPKTTPVFYLNKSSKRGVKPTQATLDILISVFNETTKPDSAEDGETVVISKISSASNKKFSLIKDIAPENWYNILVQLVHEPIQVGNKMHLWVTDYSSNSMLAYSNGTFGDELNYLGDMNDDNAAPPCRTTQLPAEMLLKVTLYGAHMDEFLSLEPKVSQWFHLQNVKIGFHGAYTPQGAIHETANFTHDVRVKKVVVETEFSDKESHLYAAARRRNNFLRNKSQSTPKESSTQQSPPAQLNEAKDNNKPSAPPPSKQKRNGRDRRKAKEAKIKAQEELDIQRKLPEDMTLQVVCETHTSYISSVAEMLRIVSYDAKVDGELVKIDCPFNLAKYLAVVRIVDFQPPDIRDFTQSRLVYKDGQPLLLSDDEESESEIDFNPTLMSESWEWGFSLKLQDAMVSAQTGTPPFVWVNVNNDSAQYLLDMEAVNLRENDDALAKLKHKMFHLWDRLEEVKRAEEANKKGLLNKAKGAQRNDEMPHHSSDGEQSSSVSRKSGSAKPTRCALKPKAFKCCIQQYGVVLPTRNPRDANVDDRNKYTRQYMLFGTRLRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPJ0</accession>
    <name>A0ABR3YPJ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetylglucosaminylphosphatidylinositol deacetylase</fullName>
            <ecNumber evidence="2">3.5.1.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">GPI12</name>
        <name evidence="4" type="ORF">Cpir12675_005475</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PIGL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.89" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000189">
        <property type="protein sequence ID" value="KAL1890256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000225">
        <property type="term" value="F:N-acetylglucosaminylphosphatidylinositol deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="entry name" value="LmbE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993:SF11">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="LmbE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="329"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="331"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="344"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="368"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="417"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="431" mass="47291" checksum="0B69661F7596725A" modified="2025-10-08" version="1">MKMVSAGLRLHDPAMASLLAVGAALVALPALYASLASAVQPRLPILHNKRVCLLIAHPDDEAMFFAPTVLALTRPETGNHVKILCLSSGDADGLGETRKKELQKSAVLLGLRTENDVFVVESPDFPDSMTARWDEGKISNFLARLFTTIHSATQTPISNIDVIVTFDQHGISSHPNHISLFHGARTFISKLARIANDGGRSPVDLYTLTTVGMLRKYVGFHDALVSLLVWLGSGTGFVSPPATEITADDNTGEEDDSARESPKSLIFFSSFRGSSRDIPSVTRARAAMTQAHVSQMRWFRWGWITFSRYMYLNDLRLISPVALDLTPSDNVSEDAPDDAEESAEAASDVDVSNAAAPVPAAPTPVIDSEPKSHEAKREKEKHMRERDPEKDRSKQRQRSEKAPSVEAEAEASEIHKSERKHKKHGSRKSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPU4</accession>
    <name>A0ABR3YPU4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fibroin-3 related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005453</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000187">
        <property type="protein sequence ID" value="KAL1890283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037504">
        <property type="entry name" value="PSI_induc_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40018">
        <property type="entry name" value="[PSI+] INDUCTION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40018:SF1">
        <property type="entry name" value="[PSI+] INDUCTION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="478"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="530"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="583"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="596" mass="63004" checksum="CC706DC6669D6717" modified="2025-10-08" version="1">MPTIDLAMARSLKGTTWEILSEGIISALNRRDVSNSVGDLSNTVDTISNTASDVSNSVNDVKTALSSWDNCMSVSWCKWPVIGLIVFGSLMILSVVWCAVRCLCCGLSCCCECCYCLKCCGNCMGCCESPDNKRKHKYLDDPFIPPNHSQNAGYQMQPQMKTPNVAPTYNMTPAVSTPAALPASGPPQYAEFDMGKKSGNEDALPAMPTWDDAGTKKISLDNGQGGVEMDQLNKPSPSATPAPAATPAPTAAVGALGAGAAGLAARANNASGNTDTYRNAPPANQYDSQAAFARSNTPGFGSQAGRSTPGYGNQSGRGTPGFNNQQGGMNGYGAPGNDPYSQQNNSAYNTPVDTGYQNGQNNSYQTVSSHQPQQLGYDQSRDSNFNAYDSVYSTNNALPSPQESAFHYDNPSYQQSTQSHNASYNNAGYSQDQGYGHQNARAMGPYEQQQTDAYGAVNKHTTPVSTYGGHSDVFEMPAADYSSQGGSMAAQQNGAYSSQPSQPGKFVAYNPTGASTDIGGLQNAGGFDFNSGNSRPGTSSGPQNNQQIQPLMTGYDVQRQGTAPPQELYANHGQNSNRAMYTSPAPSRSSPAWPTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQK8</accession>
    <name>A0ABR3YQK8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Chalcone synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_005401</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000184">
        <property type="protein sequence ID" value="KAL1890387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00831">
        <property type="entry name" value="CHS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012328">
        <property type="entry name" value="Chalcone/stilbene_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001099">
        <property type="entry name" value="Chalcone/stilbene_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011141">
        <property type="entry name" value="Polyketide_synthase_type-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11877">
        <property type="entry name" value="HYDROXYMETHYLGLUTARYL-COA SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11877:SF46">
        <property type="entry name" value="TYPE III POLYKETIDE SYNTHASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02797">
        <property type="entry name" value="Chal_sti_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00195">
        <property type="entry name" value="Chal_sti_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000451">
        <property type="entry name" value="PKS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Chalcone/stilbene synthase N-terminal" evidence="5">
        <location>
            <begin position="58"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Chalcone/stilbene synthase C-terminal" evidence="6">
        <location>
            <begin position="233"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="384"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1890387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="424" mass="45469" checksum="6A779E541D92347A" modified="2025-10-08" version="1">MDLSILGIKAVYPPYRLGPTALAEIAERFYPDSPAMKKLLAINKYTGVDTRSSIGTPDHPLVNMEKPPSISQLHEAFMTYGLPLAVEASRSALERAGVDVSELTHIVATTCTDSANPGFDHFLAKQLGVKHAVERVLLHGVGCSGGLATLRTGANLALGHTARGKPARVLCVALEVSTTLVRSELDSLHETQEVRIAPVLFSDCGAALVLSNGIGHTEKTAMPMYDLLGWNYHVIPDTEEYLGFDADAMGWKVILKPNVPKEAAKAMPETFKNLITSLEKLPEGMSNPQDFDWALHPGGSSILTGVEKALNIRPEAMRASYNVYVNHGNSSSATIFSVLEKLLQKDINAYAPNGNPKEYVVGCAFGPGMAIESCMLKRRGVSSHVAGVDTPPEDGSETAPSQVGGSGYQDEEFIAIALEEVDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQR4</accession>
    <name>A0ABR3YQR4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA-dependent ATPase fun30</fullName>
            <ecNumber evidence="7">3.6.4.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">FUN30</name>
        <name evidence="7" type="ORF">Cpir12675_005280</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000176">
        <property type="protein sequence ID" value="KAL1890680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10799">
        <property type="entry name" value="SNF2/RAD54 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="478"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="848"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="209"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="217"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="255"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="275"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1890680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1038" mass="116137" checksum="D5F1B48D28163CB8" modified="2025-10-08" version="1">MPSFATSRSRSFVDYPPPRSTPPEFRDTEDDDNDEGNEQDSSPEIATIPLDMVPCSSPIQPTQVLGRALPLALQQSPTPIHSLSPSPPVIEVPRSSPLQATKQAHLTKQGMISQFFKATTPITNSTASTTASASPLSAPVTALRITDGNANKKRCFDLIEVSDDDDGHNRADIRRTQFASSTIKRDVSPMHKKSKLAIGKLDFSSFQYTPPSPKSAKVQTFTDLTKPPLNNATRLAQQSGSKPPEILITSSPPKGRPRRRLVRGLRPRSRSPSPNTSQEAPLKSSTPLPAPIVKKKLVRPKPLIISDDEEDELAIDSYVSRDSTPEIVGQSGNKIVDMLNEIIMSDLAALTGDKEDSLTHLLSHRPFRSISQIEKVSKPKTVRGKKQMVNIGEAVVEKVSSFTKAISAVDQIVVESDRRAQEIKKEIDSWGMNNVGQAAKATSSTAHRGRMWKMGQPANMNPALPMHDYQVFGVNWMNLLFRKGFGGILADDMGLGKTCQVIGLMCRMVQDYEADEMEDMPFPNLIVVPPSTLDNWLAEFEKFAPHLSIVKYSGSQDARNDLVDDLLGDDEVAHVILTSYTQLSTNVDIHNMNRLNIQNAIFDEGQILKNPTTKQYQRLARLKVNWRLLLSGTPIQNHLMEMISLLSFVDPHLFSTHMEEIQYVFDHKIHSKNLSNTALLYGERVNRARSILEPFILQRLKDQIGQNLPKKTQRIIRCDLPDKQRKLYDKYEKLFRAENDQKVKTRKSGARDNDMNNIWIQMKKAALHPQLFRHHFTDKMVHDMAQILYKKVDHRELDLAESKFDLLHNDLRGRSDFDLHLYCTDFPRFLKEFDIEAGSWKTSAKVLKLLEMIDEYKKNGDRVLVFSKFSMVIDILSYILNRDGIPHCQLTGKSAVGDRQAEINRFQRNPDIPVFLLTTGAGGTGINLTAANKVVIFDMSSNPQDDKQAENRAHRLGQTRPVEVIHLIARNTVEELIYLTCQKKIELANKVITSGAGSGAATAEATATGTSESATETQLKNTIRGLMDQGYTVNSNDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRX5</accession>
    <name>A0ABR3YRX5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Aspartate aminotransferase</fullName>
            <ecNumber evidence="8">2.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">AAT1</name>
        <name evidence="10" type="ORF">Cpir12675_005121</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:21824"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="EC" id="2.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Homodimer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.1" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000163">
        <property type="protein sequence ID" value="KAL1891113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004069">
        <property type="term" value="F:L-aspartate:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000796">
        <property type="entry name" value="Asp_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006719">
        <property type="entry name" value="PRK09257.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879:SF22">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00799">
        <property type="entry name" value="TRANSAMINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 10" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="9">
        <location>
            <begin position="52"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="422" mass="45662" checksum="F12D0F91AB3BDEA1" modified="2025-10-08" version="1">MISSALRSRAAATAAIRAAAPSRAQSTWTAVPLGPPAILGITEAFKADKFAEKINLGVGAYRDDSGKPYVLPSVLAAEDKITQARLNKEYAGITGVPDFTRAAAKLAYGDNASVLDRTAITQSISGTGALRIGGAFLARWYPGAKKIYLPNPSWANHGAIFKDAGLDVGTYQYYDEKTIGLDFEGLVKDIESAPEKSIFLFHACAHNPTGVDPTSEQWREISQKVKAKGHFVFFDMAYQGFASGDTTRDAFALRHFVEQGHNVALSQSFAKNMGLYGERVGAFSIVTADPKEKTNVDSQIKILVRPMYSNPPVHGARIASEILNNPALNQQWLGEVKGMAGRIISMRSLLRGNLEKLGSSHDWSHITSQIGMFAYTGLSKENMKKLATEHSVYATLNGRISVAGITTKNVERLAESIFKVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUV3</accession>
    <name>A0ABR3YUV3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Protein-S-isoprenylcysteine O-methyltransferase</fullName>
            <ecNumber evidence="3 10">2.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">STE14</name>
        <name evidence="12" type="ORF">Cpir12675_004857</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + S-adenosyl-L-methionine = [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:21672"/>
            <dbReference type="Rhea" id="RHEA-COMP:12125"/>
            <dbReference type="Rhea" id="RHEA-COMP:12126"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90510"/>
            <dbReference type="ChEBI" id="CHEBI:90511"/>
            <dbReference type="EC" id="2.1.1.100"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endoplasmic reticulum membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.100" evidence="3 10"/>
    <dbReference type="EMBL" id="JAWDJO010000148">
        <property type="protein sequence ID" value="KAL1891671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004671">
        <property type="term" value="F:protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007269">
        <property type="entry name" value="ICMT_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025770">
        <property type="entry name" value="PPMT_MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12714">
        <property type="entry name" value="PROTEIN-S ISOPRENYLCYSTEINE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12714:SF9">
        <property type="entry name" value="PROTEIN-S-ISOPRENYLCYSTEINE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04140">
        <property type="entry name" value="ICMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51564">
        <property type="entry name" value="SAM_ICMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10 12" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="8"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1891671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="285" mass="31833" checksum="DD995CAEA6CB212D" modified="2025-10-08" version="1">MAGRSRKASPAPSAPSAPSTSPAASPASNETRPLTTAPRSPPIEFYRGQARSLSGIAFRAFCLGVVFSASLVLVPLTAYGASEPYFVFWRLPFFLGTLGAFHFLEFWTTARYNTPAADISSFLLTANWPLYTIAHSAAFFECAVVNTLWPWRSWGPAAGGTWAGYLCVAGVALTLLGQTVRSLAMIQCGRSFNHLIQQSRAAEHRLVTNGIYSILRHPSYFGFYWWAVGTQLAMGNVFCLAAYVLLLWKFFANRIPFEEHHLLQFFGEEYMNYRRRVHVWIPLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV76</accession>
    <name>A0ABR3YV76_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Hepatocellular carcinoma-associated antigen 59</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_004828</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TLS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000146">
        <property type="protein sequence ID" value="KAL1891787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010756">
        <property type="entry name" value="Tls1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13486:SF2">
        <property type="entry name" value="SPLICING FACTOR C9ORF78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13486">
        <property type="entry name" value="TELOMERE LENGTH AND SILENCING PROTEIN 1 TLS1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07052">
        <property type="entry name" value="Hep_59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="254"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="343"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="178"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="255"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="347"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="386"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1891787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="404" mass="44336" checksum="A5E95578C503E86C" modified="2025-10-08" version="1">MSDSLQRTAEEQAPIIFKSKKNRKQIRTRPSTVDTTINIESSTNVVTDAHASSITANEAFSNPKMVAAGPAAPGDGSLEGHLSDDETIPALSGVLRKAKKSRLQGVAFRVEASRLTDDDGEEDGMALVVRDKDGEGEEGVIVGGIKNFAPQTGILGNLVNHHMDQYVESRLAKRHQPSTDPNQKNSVDAANGALNSSFPFAAPLVSAPTLVAKVPEGQKPTQSGKLMEVDLGDEARMKNIDSIERAKRRFIGESDANSVGDTDSAQRNKRIRDRKASDEIKRDQVVEAFLHENKLDVYDISQVHGATRNFGDENLNDLPADDRVAEKFRRDFMDAMSQRIRRRRAARAPAINNQAPRPGAKRDDEMLKGPKLGGSRNTRAQMRDILLQKEKEKGKGNGNIRTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVX2</accession>
    <name>A0ABR3YVX2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amine oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004510</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000129">
        <property type="protein sequence ID" value="KAL1892539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050281">
        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742:SF382">
        <property type="entry name" value="AMINE OXIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742">
        <property type="entry name" value="FLAVIN MONOAMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046855641" description="Amine oxidase domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="domain" description="Amine oxidase" evidence="2">
        <location>
            <begin position="180"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="681" mass="74882" checksum="1DF87A696928DAF6" modified="2025-10-08" version="1">MKTSATFTSLVLGASAAVTPRSPEPITLETRSSLNSRVANVHLKFAEPISGLVTYTYSECGSEFGQHDHVVARTSDHSNDRLVWVMPAGVAPGGCLSAWSEAGVLLGRSAEQAIDHSNSYRVKRDLAAKAKRDGIAMPDVPNIDMMGPWFDGVAALDGKSIGAVNSNIKNKKIGILGAGMSGLMTYLVLHQAGFKNIEILEAAQRLGGRVHTEYLTGGPFDYSYQEMGPMRFPYQVVYNNITHNITDHQLVFQLATELNTLNNHNKNWSVDFIPWYQSNKNGLVYKNGFKLPSGLPPTVAQIAANASLGVSTVYDEATLEVETKVEDITSNSTFLAEIADNMFKAHSDFVANGLGGKPGDQWSEFAYMANYLGATLNSTDMLNGGSSSFWDSFYEGMYFSASTWKTIDGGLSRLPGAFHPLVDKVVRMNRRVEAVENKNGQVNVKWREHAGEVSAKTSTYDYAVVAVPFSIVKRWRLPKMETSMKNAITKLNYNSACKVALEFSHRFWEHYENPIYGGCSTTSDIPGVGTICYPSYNINGTGPASMLASYISGTQYGLSWAAAPEVEHVNAIKEAIFEIHGDVARKSYTGKYNRRCWANDEYQAGSWASPTVGQHETYIPEYFKTHNNLIFVGEHTSYTHAWIASALEAGVRGSVQLMLELGLVDEAKAATEKWMARWIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW86</accession>
    <name>A0ABR3YW86_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000137">
        <property type="protein sequence ID" value="KAL1892152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013268">
        <property type="entry name" value="UTP16"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08297">
        <property type="entry name" value="U3_snoRNA_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="259" mass="28153" checksum="3F9E85366D28A493" modified="2025-10-08" version="1">MVSSKFSRRKALDNSAKQKSPIVSRAPAVKKFDGDDEDMADQIEEHTSRIEAVPASPTDDSEADSDDDAPEAISTSAAATIAKQSAKAAQKAIQESAAAEKKKRQERDLKFKEQAAARKAREEKLEAEIAAAKALLAKPSTATSEEDDESRAARRRKTAALPDVLPLEFLDSDDSDNSDDDASHGKGADKSMAATSRTAKKIMKRTDADRVVGGTTYRVVKKTKLDLVPAAKKHTVHIKSQLLRRKRTGVPVKKGFLQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXC4</accession>
    <name>A0ABR3YXC4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase</fullName>
            <ecNumber evidence="10">2.7.8.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PGS1</name>
        <name evidence="12" type="ORF">Cpir12675_004501</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>a CDP-1,2-diacyl-sn-glycerol + sn-glycerol 3-phosphate = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12593"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60110"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="2.7.8.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Phospholipid metabolism; phosphatidylglycerol biosynthesis; phosphatidylglycerol from CDP-diacylglycerol: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the CDP-alcohol phosphatidyltransferase class-II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.5" evidence="10"/>
    <dbReference type="EMBL" id="JAWDJO010000128">
        <property type="protein sequence ID" value="KAL1892572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008444">
        <property type="term" value="F:CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd09135">
        <property type="entry name" value="PLDc_PGS1_euk_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09137">
        <property type="entry name" value="PLDc_PGS1_euk_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016270">
        <property type="entry name" value="PGS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12586:SF1">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12586">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000850">
        <property type="entry name" value="Phospholipase_D_PSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="11">
        <location>
            <begin position="191"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1892572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="531" mass="58657" checksum="B8D943AEC352A04D" modified="2025-10-08" version="1">MFQGLRRCAPRLCGQARQLSLRSTVYQPQCRMYSSANGSASSVSADAAAGYLGAGSVVPIVTELDKIAPSFNIDGSQIQVIQSPAEFYKTLKDKILSAKHRIFLSTLYIGKSERDLINTIQAALRTNPELQVSILTDALRGTREAPQPSSASLLAPLISEFGADRVEIRMYHTPNLTGLRKKHIPKRINEGWGLQHMKLYGIDDEIILSGANLSMDYFTNRQDRYHLFSSKHITEHFSKLHHAIASLSYLIKPSHDPAKFEMVWPNTGPAPVENPTAFVAHATSVLTPLISLSPAAATQQNPARNNTRVYMLSQMSQLLQPDSSTELPAVTHILQTLSRPEYAQSLWTFTAGYFNPAPSLTKLLLGSASKSGTVITASPYANGFFQSKGVSGMLPDAYTYLARRFLRAVHTAGRDSSITLKEWRRGHVTEPDGWTYHAKGLWVTLPGDNNPAISIVGSSNYTKRSYSLDLEAGALIITRDEELKRKLGCEQQWLQEYASKTTIDDLAKPERRVGIHVRLAMWFVQAVGGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXE5</accession>
    <name>A0ABR3YXE5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Guanine nucleotide exchange factor lte1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">LTE1</name>
        <name evidence="6" type="ORF">Cpir12675_004410</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000124">
        <property type="protein sequence ID" value="KAL1892712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06224">
        <property type="entry name" value="REM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF363">
        <property type="entry name" value="PROTEIN SON OF SEVENLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00229">
        <property type="entry name" value="RasGEFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="5">
        <location>
            <begin position="466"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="4">
        <location>
            <begin position="1699"/>
            <end position="1944"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="28"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="280"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="660"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="725"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1034"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1109"/>
            <end position="1223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1279"/>
            <end position="1304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1442"/>
            <end position="1479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1550"/>
            <end position="1615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1638"/>
            <end position="1674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="51"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="283"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="660"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="755"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1113"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1127"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1158"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1183"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1193"/>
            <end position="1203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1295"/>
            <end position="1304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1442"/>
            <end position="1452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1602"/>
            <end position="1611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1892712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1947" mass="213263" checksum="68A3518F96807D7D" modified="2025-10-08" version="1">MDTPSNGLPEPDPEPVYTRTIKTHIHLQPQPLNVSPHSVDSAHSRLRRAASKSTTSSKRAVSSKVPTKLKVAPSASLKPLVPKNERKHQENDIHARIRKKSDAERLVADGACESPQRRRGLSVSNVGNNGKIYLRPIVRPANQRYFTQPNMPTTTLPTTAVVDTTMVPDASQPAGESGDANIPTQPRKPQLCVSNIEKSSDLHLSQWETPSPTIIAPNQPLMGSSPDVDIQANPSTVKTIQGRRRAASDAARYDAPALPSLTISPDYGTSGALKIVISQSHTSSHDQENNKENTRPRTAGQTDALPFIDVPIPSPRIGQPRFTVRGTPVLRVSDYTATEDLHSSIAHTLSAIPTPLPRSSYVAQSLMSPSIHGASREPTWMMVQTPRRFLPSMPTIPMLTVTPVKISQSEPTTPMPRVSIDQEPPITAAAVGPVHVTAREEVGPAMFDALTFKPACDDGNLVRYSPSGAIMAATPPRLIAEITSPCILDYELLSDFFLTFRAFLEPLDLVCMLVSRFHWAADRNDEIGMVVRVRTFVALRHWILNYFVDDFIPNLELRVSFCNLVNELSSNLVKIGKDVRPHLKIVNELKKCWRRVCAQFWDGDDDSISTSSGTDPDITPGGIAGHRDMNINPAYWEQKPILRPSIDNTRGELENNPSIASVIQGSSNNNGRSPVESVKSIPQHPTSHDNGHRHGANPLSVSSIDVASCTFPTVKNLHKFGFTGSSSSQAHSARPATAHNIAPSGGIASAPKNIVGKRVRPHKRNASLSDSLRDHTEPPTRPTDNMESHPVLGSLVRGDLFPPSQALVEAGHSSDEADNMRWSTMDSESNVTSNNRHYASGPGVKKIFDTVKRALSTTRCPITGLRLARQQLRVSRLLSNPAPSSGVVPLLKPKKFDENLAVRVDLLGAAIADAFKSAVRDEQTGAGSQNGLSLQESALGWQDTEEQYRAPTYASAHLDTSFDGMSTHSGTSYRRTAHKRVLSDGAITSGSKSIMIINDTRHEPFDLSTLPIHIGSTMPSGPPAERFTEALTHVGDLTPPSTPPDHLHEVPQQTSHMPNHSFFVRPDDVHTIIPPFVPDLQSFLNGGCLSPNQAFRSPQTATFPRAIAIGTDPSYTNSSLPLPQQAETKDEGDTHGEVETCQEYSASRHLSRADDSIVASTVTQSHRHSTMSGADQPHTSFHSSHHRAHRRSVSASSFASSASPEIGDKAQPARMLRRRPAGNLREVSTVNDLDQHLSMFRSRSMTTIDTFTDSIRSSYRISYNEGPSLSQHKPYHEAVSPSVSEPIPHTVPFGSPTSPQQPSFKKLSLFSTHSSMHHPMRSSFEAELRKLAAIPDDVDDGVEIALMKLEGRYEKPATFTELTPAPPRLRKKRVSLSQLVTGNRTIIDTERRQNRQASLTGQGSIVSPVMNMTGLSLEAVNIPGSPLCNSFLPAGPMPRYEADTVHFSDDSSSKNPSQSLCSQERESLASFNNEGSLENHDRDWAKQAAYISDDGSTARSHDLTSVLNPALCHAMPIGSDAKHEDSICQPKIRISGSFLDSNSYNERITRDSLDGGVSPATSDYLGHMDKHGSPRLGENDNSSSHIAPPSPPMTLEQALNIPSSPEQSPKVQVPPVPVNFTSSIIDMQLSPFTMYKPLPPTPEATPTTTHSHTAEYPSARPSQESPVSGAVATEGQTNKEGVVASQRAASHLPFILAFDSDVLAQQFTLIEKEALIEIDWRELVEMGWKTSTNGLWRSWLDFLRNSDSRGIDVVVARFNIMVKWAVSEIVLTQNINERARCIIKLIHIAKHCRRYRNFASLAQITMALTSPEVTRLAQTWALVPAAEVSVVRSLETLMTPTRNFYNIRSEMETGSDKGCVPFIGIYMHDLTYNSQRPAHVPASSQTAGPLVNFERYRRTAAVVKTLLRLFEASALYDFQPVEGITERCLWVCALHDEEIRSRASQLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYS8</accession>
    <name>A0ABR3YYS8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">40S ribosomal protein mrp2, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MRP2</name>
        <name evidence="4" type="ORF">Cpir12675_004268</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000117">
        <property type="protein sequence ID" value="KAL1893077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_uS14"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006477">
        <property type="entry name" value="PRK08881.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19836">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19836:SF19">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US14M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="114" mass="13560" checksum="A209BD5F79AB4571" modified="2025-10-08" version="1">MSMFQRAKKLDLGCFVNIRTIRDHTKRKVFEQFEPERQALRYIIRNTTLHPRIRTEAQLQLAQMHSYTRPTMIRNRCILGGKSRGVFRDFKMTRFNFRMQALAGDLPGVKQASW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ07</accession>
    <name>A0ABR3YZ07_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_004086</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000108">
        <property type="protein sequence ID" value="KAL1893478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF2">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="3">
        <location>
            <begin position="16"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="353" mass="37287" checksum="588B1CAB8172A251" modified="2025-10-08" version="1">MASNRAITITTNGKAEILDTTVPELPGPDYILVKVTAVALNPTDWKHIHQADFLGCVGANLGCDYAGIVEKAGTGVTKEFKKGDRISGPVNGGNGLSHVNGSFGNYIVVKGDLQIKTPDNISDEQAATLGIAVTAAGQGLYQKLGLPLPSPNSSSTETILIYGGSGAMGSMGIQFAKLSGFKVITTCSPRNFDLVKALGADHVFDYNDAGSAAAIRQLTNDKLAYAWDTISKPETGRFCAEALSTEGGKYSSLLPGVEDAIKEVNPRVQVDMSVFYAAFGEPFKLVAEVPADMENYEFAKKIWSLSAGWLSEGKIKPSEVDLNRGGKGFEGIFAGLDYLKNGNVSGAKLVYSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ74</accession>
    <name>A0ABR3YZ74_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Intradiol ring-cleavage dioxygenases domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003994</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000104">
        <property type="protein sequence ID" value="KAL1893694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03457">
        <property type="entry name" value="intradiol_dioxygenase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000627">
        <property type="entry name" value="Intradiol_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34315">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34315:SF1">
        <property type="entry name" value="INTRADIOL RING-CLEAVAGE DIOXYGENASES DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00775">
        <property type="entry name" value="Dioxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047129254" description="Intradiol ring-cleavage dioxygenases domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="Intradiol ring-cleavage dioxygenases" evidence="3">
        <location>
            <begin position="131"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="398"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="461" mass="48061" checksum="71212A87D472C8EA" modified="2025-10-08" version="1">MLFARNILASLALASTLASGHPGHSVAEEALERRTFLNSVKRSSLAHCASKLKARGVIERNIARRTAQLEKARAKRSIRKRDLETVLATDHNMTSMGYTTSTDAATLFAGYNSCLLTPEVTVGPYYVSGEYVREDMSEDQDGLDLVLDYQVIDVDTCEPVPNVYVEIWHCNATGVYSGVVASGNGDSSDASNLDNTFLRAIQGTNDDGVAQFNSIFPGHYTGRTTHIHVMVHTNATLLANQTLGSDNYASHTGQSFFDQSLIAAVETLEPYASNTQELTENADDSIMAEEAATDGVDPFLEYTLLGDELSDGLFAWLAFGINTTQSTSITPASFYYESGGVSNSNGGGGSPPSGSGMPSGGTPSGSGAFGSGIPSSATLASSSTASSSATSVYVADASSSSSSSFAAAATTPSVGYGDGGSAPHTPKLDGATPVVNSSKKSKQTEQAVQNDKSNSKSSCNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z025</accession>
    <name>A0ABR3Z025_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">methylcrotonoyl-CoA carboxylase</fullName>
            <ecNumber evidence="3">6.4.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">3-methylcrotonyl-CoA carboxylase 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MCCC2</name>
        <name evidence="9" type="ORF">Cpir12675_004129</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>3-methylbut-2-enoyl-CoA + hydrogencarbonate + ATP = 3-methyl-(2E)-glutaconyl-CoA + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13589"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57344"/>
            <dbReference type="ChEBI" id="CHEBI:57346"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.4.1.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-leucine degradation; (S)-3-hydroxy-3-methylglutaryl-CoA from 3-isovaleryl-CoA: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AccD/PCCB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.4.1.4" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000110">
        <property type="protein sequence ID" value="KAL1893430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004485">
        <property type="term" value="F:methylcrotonoyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045190">
        <property type="entry name" value="MCCB/AccD1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22855">
        <property type="entry name" value="ACETYL, PROPIONYL, PYRUVATE, AND GLUTACONYL CARBOXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22855:SF13">
        <property type="entry name" value="METHYLCROTONOYL-COA CARBOXYLASE BETA CHAIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="7">
        <location>
            <begin position="71"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="8">
        <location>
            <begin position="331"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00026116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00052347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="576" mass="62255" checksum="D19E6E48985C6C0D" modified="2025-10-08" version="1">MLLLRPQVGLNGIRPSKTRHLPLALLPVLWNHTQSRTAAIYTHPSQAAKVSIIKSDIDESSKQFRQNYKDMADVIHKVSSLTLKVQQGGPATARQKHESRRKILPRDRITGILDPNTTFMELSPLAGHDLYPEAEVPSGGIITGIGIVEGVRCMIVANDSTVKGGTYFPITVKKHLRAQEIALENKLPCIYLVDSGGANLPHQADVFPDRNHFGRIFYNQARLSAAGIPQISAVMGPCTAGGAYVPAMSDENVIVQNQGHIFLAGPPLVKAATGEEVTPEELGGGAMHTSVSGVSDYLALNDAHALVLIRRCISNLNWPAYTDASIQPSQTPENPIYLAEDLRGIASTNLRTPLPVHEVIARIVDGSRFSEFKSDFGASLVTGFARIEGHRVGIVANNGILFASSAVKGAHFIELCSQRGIPLVFLQNISGFMVGVDAEREGIAKHGAKLVAAVACSEVPKFTVVIGGSYGAGNYGMCGRAYSPRFLWMWPNARIGVMGSEQLTSVMETVGKAVDPNLKKRIDNESEAVYSSARLWDDGIIMPEHTRHYLGMALSIAVSGRNTIKANETKFGVLRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0L1</accession>
    <name>A0ABR3Z0L1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">V-type proton ATPase proteolipid subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">CUP5</name>
        <name evidence="13" type="ORF">Cpir12675_003809</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10 11">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Vacuole membrane</location>
            <topology evidence="11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the V-ATPase proteolipid subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000096">
        <property type="protein sequence ID" value="KAL1894121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18175">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6C_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18176">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6C_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.610">
        <property type="entry name" value="lithium bound rotor ring of v- atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000245">
        <property type="entry name" value="ATPase_proteolipid_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011555">
        <property type="entry name" value="ATPase_proteolipid_su_C_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01100">
        <property type="entry name" value="V_ATP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10263">
        <property type="entry name" value="V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00122">
        <property type="entry name" value="VACATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <keyword evidence="11" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="88"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="125"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="12">
        <location>
            <begin position="16"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="12">
        <location>
            <begin position="92"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00045519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00046480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1894121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="161" mass="16273" checksum="BFF4897DCD8BFF60" modified="2025-10-08" version="1">MATELCPVYAPFFGAMGCTSAIVFTCLGASYGTAKSGVGVAAMGVLRPDLIVKNIIPVVMAGIIGIYGLVVSVLISDGLKQQLPLYTGFVQFGAGLSVGLAGLAAGFAIGIVGDAGVRGSAQQPRLFVGMILILIFAEVLGLYGLIVALLMNSKATLGAEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z126</accession>
    <name>A0ABR3Z126_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000114">
        <property type="protein sequence ID" value="KAL1893224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="561" mass="62210" checksum="A0B6C44B8C8D5D5A" modified="2025-10-08" version="1" fragment="single">LAYNPMAHFSRATRRFDADTLHTRLAKCAREGDESSQSPINKEELENGLNRDAKLGRCHVDVEDVVEQSASSSCRESKSQSQTSIQLQQNKTEESPIQYQPCPETSHTRDTPQVEGRKQRADDDVAKRIDACVSPAGPTLGSKLSEALGSDLVATQRCVREGLEDVDTGRSCDAGSFVYSHGQGVVDLEFRQRASLSTTTARVPADRQPDKSVSSIPETMQVESVGMKSLKVSQSNLQDGLNVGLDAADDVENLQGLSKPELAMYGRTVTPLLQYKDIGCQTEDGLFSHTKTRQETMQEGLTSKSQLIGHLPVSEIRRQDRVQQVQCQPEVAADDLLCNRPQNFDLQPSFAARPHQHTGCTKYTTSGSLPNDGSAACLEGNNDVPMEGCTWGLGNVSNSLHQSSHHSAIHLRKFPILEEGSRPQACQQLKLHNRAGDSKDWASFFPDRALSGDNMPVTETDSVIEGSWPAAVVETSLLPHDSRASCSWAMLNSFDPQSHGYPLKQVHQNHEILQPQAKRLKVEIESKDLEQFVPRNERGQIYEVVDEAHEEMTRFWRPNRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1K6</accession>
    <name>A0ABR3Z1K6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003817</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000097">
        <property type="protein sequence ID" value="KAL1894082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="114" mass="12590" checksum="5D77F3B0E2866C9A" modified="2025-10-08" version="1" fragment="single">MENHPVVDHPPAPPASATDDQEIFDNIDGRMHGPMSRLNKKYFGNFQYVRRDALLEVQAAGRVSGRCAAPSIASSPDNFLQWLSNYVSWVLDGARDSWHISGGDVAPKHESANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z266</accession>
    <name>A0ABR3Z266_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nuclear pore complex subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">NIC96_2</name>
        <name evidence="5" type="ORF">Cpir12675_003724</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleoporin interacting component (NIC) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000093">
        <property type="protein sequence ID" value="KAL1894296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007231">
        <property type="entry name" value="Nucleoporin_int_Nup93/Nic96"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11225:SF4">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP93"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11225">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP93 NUCLEOPORIN NUP93 DEAD EYE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04097">
        <property type="entry name" value="Nic96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="16"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="89"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="382"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="31"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="89"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1894296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1188" mass="127220" checksum="7C167A9BAF85EA8B" modified="2025-10-08" version="1">MFGGAQAKPSFGSLFASSTASSTGAPPGNSLFGNSTASTQPTNSLFGASTSTPAAGTSNAPAGNSLFNSTATAPNSLGGSSLFGGSTATVTPGNATTQTGGSLFGNTLGGNPGGLPSTTPAGSLFGGGTPAQQTASTAPTAGRYLFGAAAPVATTTANTLGGGGSLFGSTLAPYNTATTGLGIGASVAPTSLGLSALAASSAAAAKPAVQSDSQAGDGKSAGAYFDSLLASTRNQQAPAGENAIDNLPSLQLGLGDIRQHLKKLGASDAQTAIDGRAIYLLNASGVDPNAAEKDLGALGPATNTRTAGNAIGSGGVSDVDVETYLSNLQSKTTLGMIRDGLDRSARAFDEFLEDNMALEWTSQRKKIYEHFGIRLREEATGSDAAAGKDTQGRFGRSRRSKMAGDGTARDSTAANRASVLGGPSLGRSIIGTPSRIGSHRTEFSDVGGNKEASAELGGGYVGDMRSLRERQGRLAKQITMLNVYRLSDRPFPILTQLGSLQTKSVEPHANHVAEAYRAMVDVVGEDAEAESWLNGATSTERQFAKMYLNENSNSPEAIEMRKRILAGANCFLERQFLREIENLIAKHPHEANLGGRPDIVSKIRAYIRLRSARKDLVPDNTELQQVQGEYVWAIVFYMLRSGHVIEAAKYVNDNLPYFRGIDRMFSTYLNGYASSEDRRLKRQLQERCVSEYTQRARNAPEHSIDPFRMACYKIIGRCELGNRSLDGLNTDVHDWVWLQFNLAREFERSNELASETFGLAEVQASIRDIGSKHFPKTPSDEAASNGSFGMFFYLQILCGLYEDAIAYLYSFAYVDAVHFAIALSFYGLLRPSDPLTADNELRSTNTRGLPLINFGRMVGYYTRDFRAANVEAAVDYLTLLGFNIDLAGEAGRRHASMCHEALRELVLETREFSSLIGDIHPDGRRMQGMIEVRGNLIGLTDEDDFITAVTLQAAAYADESGRITDSVLLYHLAGEYDTVVAIVARALSEAVALDIGENPVSLAPVKARVAGDAQSGDHSASMSLASIDEPVELARAMMGMYERDAMFHRHIQETNLSACQLLLEMSEIKTLVEHSQWAESLDRIRGLDLLPLEARGDPSKIRHFATKFAALPQTVAANVPGLITWAVMCCTRQRDMLLHGEFSGNEGTRLMVVEQLRSMTLDLTTYTSQLKYRFPPHLHEALARAAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2F9</accession>
    <name>A0ABR3Z2F9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CIT3</name>
        <name evidence="10" type="ORF">Cpir12675_003498</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>oxaloacetate + acetyl-CoA + H2O = citrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16845"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>propanoyl-CoA + oxaloacetate + H2O = (2S,3S)-2-methylcitrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23780"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57392"/>
            <dbReference type="ChEBI" id="CHEBI:58853"/>
            <dbReference type="EC" id="2.3.3.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Organic acid metabolism; propanoate degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the citrate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000084">
        <property type="protein sequence ID" value="KAL1894803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036440">
        <property type="term" value="F:citrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="entry name" value="Citrate Synthase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="entry name" value="Cytochrome P450-Terp, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007128">
        <property type="entry name" value="PRK09569.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739">
        <property type="entry name" value="CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739:SF15">
        <property type="entry name" value="CITRATE SYNTHASE 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1894803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="501" mass="54325" checksum="30BEADC3316D5785" modified="2025-10-08" version="1">MYPKRATVLAVSAFKPAANGKVEQPRPVRFFAPQLSRSYATTTAEPSLKDVLSSVIPAKRELLKKVKSHGSTSIGPLNVLHVVGGMRGLRAMVWEGSALDPEEGIRFHGKTIAECQDLLPKGRSGKQMLPEAMFWFLLTGKMPSTGQTRAFSAELAQKAELPAFTKQLLLSFPKNLHPMTAFSMAVASLSHTSKFATAYANGLGKADYWEPIFDDVISLLAKLPTIAATIYAHSYGPGENSGSKVPAIDSNGDWAYNFAVMLGKGGNEHESFQDLLRLYLALHGDHEGGNVSAHATHLVGSALSDPFLSYSAGLQGLAGPLHGLAAQEVLRWTIQMKDAIPENYTEADIKDYLWSTLNGGRVVPGYGHAVLRKPDPRFSALMDFATSQPDIVADPVFKIVELNSRIAPEVLKAHGKTNNPYPNVDSSSGVLFHHYGFKETLYYTATFGVSRGLGPLAQLIWDRVLGLPIERPKSVTLQSLLDIAQSKASTKRSVNERGKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2I0</accession>
    <name>A0ABR3Z2I0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine-protein kinase ulk3</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ULK3</name>
        <name evidence="3" type="ORF">Cpir12675_003662</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000090">
        <property type="protein sequence ID" value="KAL1894485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053235">
        <property type="entry name" value="Ser_Thr_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24361">
        <property type="entry name" value="MITOGEN-ACTIVATED KINASE KINASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="228"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="550"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="557"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="685" mass="78724" checksum="BDC90D1777B60AA9" modified="2025-10-08" version="1">MDAQISRDQQPITSPSPSTPRIAPALGLIARLYPKIGKFSPEIIERNRDRYHEPSDDADGQDIPRAAKYRKLPYIELNFGQPPKHRQGFVFGHAPEYCDVVLDKQLGTNPVHFVIGYSNEFVDNVYRLVVQDFGSAMGTMVTFGIQAAEFQSNTTWTVTGFSFADSNDISITMHNGEEYIVVPRIYDTKDENVIRAITQYSSHRPDLQLPLPAPEKSRFAVRSGTPTMAIEKQLMGCVRGFTQKVWNTSNAQAFVLKRLICLNTKEERAEWIASVRRFQTLRHEHILHLVAFKPDVHEAFMPWRPHGNIIHQFRNIMPFRFGETLVMFQQCLNALDFLHQQNIAHGNLRPENILVLTRGCECEHDKLHVQLSDFGILETKRAITDPRGSQFKAPEILARPDRSKRQFIGTPASDLWSLGVILLQAAYNRVIYSRVALRDAVNHCLYLHQMVHAWRKDELVLLIRQCIHYCAASRSEARCILTNMAEFIQTGRLTYEGPPLYACIRAKIPTEEGSRHHARAGDYLYEFMEEDQRVFHAVLRDATLKLAEKQRRRETQEEMGEFENDSDSFAEDEENREGAEDEDDDGDFEEGEEYIQWTEKVVHSSQVIRRRRRGSSNLLMTIWEAEEGSGRVMTEDERGKKSEAMFKDYECDYSSSYEGETEIESFATPANYATGRHDGSWLELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z375</accession>
    <name>A0ABR3Z375_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DRBM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003408</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000080">
        <property type="protein sequence ID" value="KAL1894993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00048">
        <property type="entry name" value="DSRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="150"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="160" mass="17748" checksum="18326E808C9D1DCF" modified="2025-10-08" version="1">MQSGFYMEYLESLCRRRGWSDPVYDPYLGTTGYTCLVLVNGRKYQTDLAYESEQLAQENAAMRAFMVCRNFSVNGGMLARNGIVQGLPAEMPRSNMVMSGNTSSTAMSTQLASHHHQNHHQSHHRSSQGHSARNHSVNSPANVQPRMGRSSSSSSSNLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3T3</accession>
    <name>A0ABR3Z3T3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cell division control protein 14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_003459</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000082">
        <property type="protein sequence ID" value="KAL1894965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012535">
        <property type="entry name" value="Cell_div_Cdc14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34065">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34065:SF1">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08045">
        <property type="entry name" value="CDC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1894965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="294" mass="32210" checksum="BFDCBDD5A4F08997" modified="2025-10-08" version="1">MEALLSLAFDNLSSYDGPKVRKGLRQVEGLLAQICLSQASSSPTSSSADITGYDPSDIEAPPARKGLAQLGDDPAFQEFFKLQEGFEWNVMLRLINTLDRLMGKGDDGQNDLLILNSLDLIQGVLLLHPPSKTLFAREQHMNLLLDLLEPVNCPAIQSATLLTLVVALIDTPFNTRTFEALDGLLTVTSLFKSRSTSREVKMKLVEFLYFYLMPETPISRDATHGSSTYGSIIMKSGSLRSGSHTSSGSEVTLVDEDTEILTTSEKQQLLGRYLSNVDDLVKDLRVCTPFGGVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3Z9</accession>
    <name>A0ABR3Z3Z9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_003451</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000082">
        <property type="protein sequence ID" value="KAL1894957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF47">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="317"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="345"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="402"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="434"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="45"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="485" mass="54054" checksum="C5FC16817A488D99" modified="2025-10-08" version="1">MEKFHDPEKRADANDDPTLKPESPEDFGFSPEKQRKIIRTIDRRLVVIVGVMYCISLMDRTNMSAAAIAGMRTEIDLLDNKYQVANLVFFITYTLFQPPSTILIRKIGPRIHLSLITLLWGGVLIGMGFVNNFGQLAVCRMILGLLEAGFFPSCVYLLSTWYTRFEIGKRYSVFYLLGSFASGCSGILAYGLMQMDGLGDLTGWRWIFIMEGIMTCVIACIGYWLLVDFPDSSRESWNFLGPRERAWIVSRVEKDRGDSAISKFNLAVFLRSGKDWKIWLYALAFFSNTTQSYAMAYTLPIILISSLKFSVAEAQCLVAPPYALAGILMYVAGYIGDRYHIRGPIVALNSVVSLVGLSIMGFASDPWFRYFGVFLTTAGSNGNIPGIMAYQANNIRGQWKRAFCSATMVGFGGIGGIAGSLVFRDQDAPGYKPGYYACMTCSVLTILVVAVLSVEFRRQNGKAARGEKVLEASEMKTDDGFRYTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z443</accession>
    <name>A0ABR3Z443_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000084">
        <property type="protein sequence ID" value="KAL1894810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052841">
        <property type="entry name" value="PMP_oxidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28040">
        <property type="entry name" value="PYRIDOXAMINE 5'-PHOSPHATE OXIDASE YLR456W HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28040:SF1">
        <property type="entry name" value="PYRIDOXAMINE 5'-PHOSPHATE OXIDASE YLR456W HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="PNPOx_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyridoxamine 5'-phosphate oxidase N-terminal" evidence="2">
        <location>
            <begin position="25"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="234" mass="25568" checksum="08E6210459BA04C7" modified="2025-10-08" version="1">MAQNPLNSEASLGENNLVQTTSLPHDVVQCLENARFLHLATCNNNQPHVSLMNYTYLPSSPYSQLPVIVMTSNPESKKVHNIIENPNVSLLVHDWVSHRPPTSSRRLSGGSPTPESRSSLATLLANLNSSAMSSISATINGSARMLKPGSPEEEFYRSKHLENNTFTENGLSFNNDHDSDNRAEDGGRECFVAGEEVNVLLVDIKDVRVSDWKGSIRDVEVVAMNGNNAAGMHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z459</accession>
    <name>A0ABR3Z459_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Nucleoporin NDC1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Cpir12675_003412</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NDC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000080">
        <property type="protein sequence ID" value="KAL1894997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019049">
        <property type="entry name" value="Nucleoporin_prot_Ndc1/Nup"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13269">
        <property type="entry name" value="NUCLEOPORIN NDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13269:SF6">
        <property type="entry name" value="NUCLEOPORIN NDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09531">
        <property type="entry name" value="Ndc1_Nup"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="10" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="48"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="201"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1894997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="632" mass="71328" checksum="95DB38453A2C9557" modified="2025-10-08" version="1">MARRIIRTPPYKDFLQAALHKRFLTTATVLIATVYVEAMLLAPWTSYLWTWFPIGPTGIRAFFLLLSGIWVLFLRIGQYHVGIRTSTSSFNCFVQNTTRMHTAEVFFAYLLSTACFWPVFLATRSPSSQMNLIQHVGADRTRLNEKPLFLGSYLALLAIAQSIYHLWKDEDRLALGCSKADKNKTNGDDAIAQQIARSIPILLVQTLSASVIMVLINTIVYHMFLRSMIWSWTLSLTRPFYNMPRTNMLPASWPLTLTTIIQCNYSGFLLLFMWHLSNTVFSSTIVKEPLKNGQPLISESRDPNGSLLNGLKSKKLSAKAFALWELNHISRSFPERRKAIFEDIDRKDGAMWSQVCMVCINTLKSIDNRIAAYDAPPPSPAPVQVSQAVEPKRRSFAPVKEDSIFQPQSKEVTIKGELEKAIGHAITSGSQTSTGLSPMARKTLKQARDRFITKEQQESIAPEHVAGWFRKMALKVIENEYFGPFFREEFRKRFAAAVLGTPYAEVSIYINAAASLSGLVVSSLTDDKLGKVYLDVGNVVRVFTAIILNIEHFKSNFPMHWTDIEAVRECPEVNAVLDEMKNGLRAIMAEFEQYATDLRLTQTDLRLAKEACAERLAEAGPAGERSEMREIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5A6</accession>
    <name>A0ABR3Z5A6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Bifunctional purine biosynthetic protein ADE1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">ade1</name>
        <name evidence="17" type="ORF">Cpir12675_003134</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the second and fifth step in the 'de novo' purine biosynthesis pathway; contains phosphoribosylamine--glycine ligase (GARS) and phosphoribosylformylglycinamidine cyclo-ligase (AIRS) activities.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ATP = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23032"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="ChEBI" id="CHEBI:147287"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>5-phospho-beta-D-ribosylamine + glycine + ATP = N(1)-(5-phospho-beta-D-ribosyl)glycinamide + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17453"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:58681"/>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">In the C-terminal section; belongs to the AIR synthase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the GARS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000069">
        <property type="protein sequence ID" value="KAL1895743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02196">
        <property type="entry name" value="PurM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.600.10">
        <property type="entry name" value="Phosphoribosylglycinamide synthetase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="entry name" value="PurM-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="entry name" value="PurM-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00741">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00138">
        <property type="entry name" value="GARS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020561">
        <property type="entry name" value="PRibGlycinamid_synth_ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000115">
        <property type="entry name" value="PRibGlycinamide_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020560">
        <property type="entry name" value="PRibGlycinamide_synth_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037123">
        <property type="entry name" value="PRibGlycinamide_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020559">
        <property type="entry name" value="PRibGlycinamide_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020562">
        <property type="entry name" value="PRibGlycinamide_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004733">
        <property type="entry name" value="PurM_cligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00877">
        <property type="entry name" value="purD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00878">
        <property type="entry name" value="purM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10520:SF12">
        <property type="entry name" value="TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10520">
        <property type="entry name" value="TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01071">
        <property type="entry name" value="GARS_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02843">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02844">
        <property type="entry name" value="GARS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01209">
        <property type="entry name" value="GARS_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01210">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="PurM C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="PurM N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00184">
        <property type="entry name" value="GARS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="16">
        <location>
            <begin position="112"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1895743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="781" mass="82973" checksum="82FF4ADDF570B6AF" modified="2025-10-08" version="1">MSLRVLLVGNGGREHAIAWKLSHSPQVEAIFAVPGNGGTASCPKTTNVTSISANDFTSLVEFAKKERIGLVVPGPEAPLVEGIEEPFRLAGIPVFGPSKEAAQMEGSKTYSKDFMARHNIPTAAYKNFSNADEALAYIDSIDHDIVIKATGLAAGKGVIIPTTKDEARTAVKDIMIDRAFGNAGSEVVIEEFLTGEELSILTFSDGYTFKSLPAAQDHKRIFDGDLGPNTGGMGCYAPTNIATKSLLETVNKDILAPTIRGLRQERCRFVGVLFTGLMITPKGPKVLEYNVRFGDPETQTVLPLLSADTDLAEVMLACTGGYLDAVDFKVDQKFSATVVAASGGYPGSYAKGTHMTVEASPENVTVFHAGTTMEGSQLKTAGGRVIAVNATAETLEAAVAKVYENMKLIKFDGMFYRKDIAHRAFNAKAKTEMTYSQAGVSIDGGNDFVERIKAAVRSTKRAGADAEIGGFGGELDLSRCGYPGAPILVGAIDGVGTKLMIAHAMGKHDTVGIDLVAMNVNDLVVQGAEPLMFLDYYGCSKLDPISATLFVEGVAAGCRESGCALIGGETAEMPGMYQEEDYDAAGAAIGVVTAEKRLPKLDTMVPGDVLLGLESSGVHSNGFSLVRKIVTDASGLTYKDIAPWEPTQTVGEALLTPTRLYVKALLQAFSKDLVKGAAHITGGGLIDNVPRMLPDHLAADIDLKSWERLPVFKWLRSIGNVPAIEMCRTFNCGLGMILAVDASKADEAYAALEAAGQKVYRIGQLIPRGDEACVLTNLESW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5Q8</accession>
    <name>A0ABR3Z5Q8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_003180</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM208 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000071">
        <property type="protein sequence ID" value="KAL1895542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008506">
        <property type="entry name" value="SND2/TMEM208"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13505">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13505:SF7">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05620">
        <property type="entry name" value="TMEM208_SND2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="165" mass="18047" checksum="6CFDD4C892ED67CE" modified="2025-10-08" version="1">MAQKAKKDMAKANISTLKNLHTLSAIFNGLFLALSLTLFKRSLVYYAVLSIPAFICQIVMEKTGRPTYDPATRALRSPGSDLSSSGLMDSMFDTIWVTWGCLVLVLIFGNGAWVVWSLVPAFALYKAYGLLSAGRALMGMGNPQSMGADMNDMAPTQSRKQRRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z635</accession>
    <name>A0ABR3Z635_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein MAK16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mak16</name>
        <name evidence="7" type="ORF">Cpir12675_003068</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the MAK16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000067">
        <property type="protein sequence ID" value="KAL1895790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006958">
        <property type="entry name" value="Mak16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029004">
        <property type="entry name" value="Ribosomal_eL28/Mak16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23405">
        <property type="entry name" value="MAINTENANCE OF KILLER 16 MAK16 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23405:SF4">
        <property type="entry name" value="PROTEIN MAK16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04874">
        <property type="entry name" value="Mak16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01778">
        <property type="entry name" value="Ribosomal_L28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003352">
        <property type="entry name" value="MAK16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal eL28/Mak16" evidence="6">
        <location>
            <begin position="6"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="204"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="211"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="242"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="288"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="298"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR003352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="322" mass="37807" checksum="173410F781F3A701" modified="2025-10-08" version="1">MASDEIVWQIINQQFCAFKLKTDKKQTFCRSNDNVTGLCNRQSCPLANSRYATVRQHPEKDTLYLYMKTIERAAYPNRLWEKIKLSNNYEKALQQLDERLIYWPKFLIHKCKQRLTRLKQVQIRSRRIAAEEERLGEKLVPKLAPKVRHREAAREKKAEAAAKLERSIERELLQRLRTGAYGDQPLNVSEAIWKKVLTAMEKEGQAHRDEDMDEGVDEDESDKASLAEEEEEGEDLEHQVEYVEDMEESDNDDGDLDELEDWLESDEDDDEEDSEESDDDDDSDKTGAKRKRGKALKLNKDRMNQRRMEAEKRPKLAEKIAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z682</accession>
    <name>A0ABR3Z682_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NRPS-like protein biosynthetic cluster</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_003074</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000067">
        <property type="protein sequence ID" value="KAL1895796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF10">
        <property type="entry name" value="CARRIER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01294">
        <property type="entry name" value="PKS_PP_betabranch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1124"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1172"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1490"/>
            <end position="1515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1559"/>
            <end position="1578"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="784"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="701"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="703"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1895796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1695" mass="185901" checksum="BDD6268A2843DEFE" modified="2025-10-08" version="1">MSLHQVPSGADLRKVPSDTAQAVLNALLEDSVRPAAQIYANFEHFIAATAPSALPDTLSLLRAYGKFYSQLPDFEKHRLASRSDRFTALQQDNLIVNLHNSYSSISDLMPSIDAPALRLPDGSNSIMHVALRKFVADFTLSLPLEDKEHHTVAVCLPNGPLLAASCLAVAGNYACAPINIAVGVEQFMADIKQAQAKYILTTPDVAEKLEMASWAPEAGVSIFYIEVDYAVNGGCFSVSTAEGVEIAQDGGRRKPNRGQDLALLLFTSGTSGTKKRVPLTMHMLLHGAVLVIDSWGLTERDICLNMMPLFHVGGLLRNIFAPILAGGSTVCCPAFDADLFWTVVDRIQPTWYYASPTMHDLIVKAMPSEEVLAKSRFRLICNAAGGLLPTLAGELKGKFKCTILPSYGMTECMPISTPPLTYKLEREGTSGISTGPDMAILDASGNQLGPMETGYINVRGSPVFGGYLKDDGSLDVSVFNTAGWFDTGDMGHMDADGYLYVTGRSKEVINRGGEIISPFEIEDAIASASLSPESPIFQRVKGCLAFSVDHEVLQEVVGVVLVTPPDKQRVDLKILQNAVASSLHSAKWPFLVVYMDSLPKSNNKIMRIKIAQRLGLPTVTDSTPYMSRHWEADCPPDNTPLSVGIPSRQCQADLSVVEKAIKELVPAGIEIEVYARFNQDKGAVETVIAPSTPMTPCFSTRMSSPNPGSISPSSTYFEDPRRPSISRLSSTMSLSLVDKVHNYMVPHTTHTLETPLPRSRASGMVDEMGLSKMLQMLQEEQAAEFGATTRGQIIATMAEVLDCSPEQIKAEEPFYKQGVDSLLVGQLASKLRSQFHVAIPSTKLYEGASPTDLAAFVDDALKNNKGTDSISNAPLPDVGRTHSSTNPFLLVFQLVPLCLIYPVRRALQWCIFMSMLASTETWASNYSTPGRLFNLVLCVAISKMSMQAVLPFVGIIVKWVVIGRYCEGLYPMWGGYHTRWWFVQKTLDICGLGFFASTDATRNFYYRIMGAKIGKNVKFRDMSLQEFDLVEIGDNVTLERSRLRPFAVERNTSMYLGKIKIGSNCTVGVASFIAPGAIIPDNTCIGPNSSSWEMDDADEGNRHLLASGTPGAHWALNLFLTKPLVLLAWIVYLLPWLAGLAGLVMSPVEMQPGWGQVYAVIHWFAAPHRVGYHFLALALQVTVSPIFVLLYAALIRVILDGIFGRLTPSTAANRSAIDRWRMDLVRQIMPIKKMLDVTNLFGSHYEMTSRCMRLMGAKVGRRVYWPGTGPKITDYHLIDIGDDVVFGSRSNLITSDAIGSDYIKIGNGAMIADRVILLPGVEVGCNTLLGSGAMTRRNGYYADGMTYAGAKKGDCTALAMSDPKKMDSYTGTSRNASSESTATEFVQDLNDAEKGVGQKGGHIYRFLKRSPKAAGSQATTPFGRAFYCGEAPYHVLGQFVCAVYNIFFAVFTKAFWNAPTVATIQIVDRIYREAEAGTWRDRDGHFHIPFLLGFMAAFTVGFLIVEIILVFIALVSSKWILMGRRQPGNYDWDKSSYCQRWQIYLAAERLRRQCMRGHGILGMLTGTYWLVLFFKALGAKIGKDCALFAGGTPTLYFTEPDLLTLGDRVAIDDASLVGHINSRGKFNLNRLSVGDRSVLRAGSRLLSGAKMEKDTCLLEHTLIMGGEIIEEGTTMQGWTGERFSRLRVPEHVTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6S1</accession>
    <name>A0ABR3Z6S1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DUF2433 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_002943</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000063">
        <property type="protein sequence ID" value="KAL1896030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018829">
        <property type="entry name" value="DUF2433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052743">
        <property type="entry name" value="Glutaminase_GtaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056812">
        <property type="entry name" value="RRM_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31987:SF11">
        <property type="entry name" value="DUF2433 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31987">
        <property type="entry name" value="GLUTAMINASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10360">
        <property type="entry name" value="DUF2433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25061">
        <property type="entry name" value="RRM_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2433" evidence="2">
        <location>
            <begin position="280"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="RNA-binding" evidence="3">
        <location>
            <begin position="501"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="417"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="559"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="417"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="559"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="621"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="670" mass="71309" checksum="03EEA87D58A24F46" modified="2025-10-08" version="1">MASRSYNNSGYIPNGTPTPQGSLPPGAAPLLPNQGRVIHTGPFRILCIADVRGNLRSLNELAKQARADHIIHTGDFGFYDDTSLDRIAEKTLKHVAQYSPLITDVIKKNIQSGGPGSVKSRYKPEQLPLSELSGLISGDFKLDVPVYTVWGACEDVRVLEKFRSGEYKVPNLHIIDEAQSRLLEIGGVKLRLLGLGGAVVMHKLFDNGEGRTTIAGGQGTMWTTLLQMGELIDTAHRVYDPTETRVFVTHASPAREGILNQLSVTLKADFSISAGLHFRYGSSYNEFSVNPTLDHYRGKLAASKASFNDVWETVKGEVEPAIQQNEAQQNLLRNALSIVEKMPSTAAGGNPFGGQSGASSALGQVDESAFKNMWNFNLADAAFGWLVLEIQEGRIGTEMKAQGFNFSHRGAKQNLAAAAVPSNGSSAAPVPSPSPALPSKTSTPIPAAVPLPIPAPSTASEGKPATPQPERAKSGKDSDRPPPSYTPVPESSSPAPKTAAQDIIGLFIMNVNSDEQVYELLAPEDHAKVIKIEKWGNSNKVAQFKTLEDRDGAMARLSDDYKSRTAEDRSRPLVKIFQHREPANPKSYNSRGGAGTWGSSRNSTGPKGRESGYRSAGGAGASDSESNTRRSGGPRGGARSSRGGGGERSHRGGRRGGGGGGASSPAPNES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6Z1</accession>
    <name>A0ABR3Z6Z1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoglycolate phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002810</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000059">
        <property type="protein sequence ID" value="KAL1896406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43885">
        <property type="entry name" value="HALOACID DEHALOGENASE-LIKE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43885:SF1">
        <property type="entry name" value="SUPERFAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G13290)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1896406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="252" mass="27255" checksum="475BD5B9999C3023" modified="2025-10-08" version="1">MAAFDSSTMPRSISATTVRTPRVFAPLKNGTATTAGAGSSGPAQELPTLEGVVFDVDGTLCQPQTYMFGEMRRVLGIPKTVDILDHVYSLPEDNQAAAHEAIRAIERRAMNEQVAQPGLAELMQYLDSRGIRKGICTRNFELPVKHLLDTYLPDSLFHPIVTRDFRPTKPDPAGILHIASTWGLAGSDASGLIMVGDSIDDMTAGKRAGAATVLLANEVNKHLVEHDHTDLVIDRLDELIGVLETGFVGRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z737</accession>
    <name>A0ABR3Z737_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000063">
        <property type="protein sequence ID" value="KAL1896032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="425"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="506"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="549"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="587"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="982"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1010"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1066"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1109"/>
            <end position="1277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="222"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="598"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="992"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1018"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1075"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1109"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1122"/>
            <end position="1158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1159"/>
            <end position="1205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1236"/>
            <end position="1253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1277" mass="137606" checksum="1FD4F29ED989D7D8" modified="2025-10-08" version="1">MSSRQSSPGRTIASMTLRSSPTSTPIASTTPAPILMSSSRVYGPPPAKMEQTVFPTRRRTIRTYGKDKVSSGARTLKRKAAMTPVEGQKTLKQKTLTQFDCLQSDSYEFVGTPQVTFTKDERKDIQGNVVEETTPSARVRWDDAVVGGEEEPEVPTATMIKRQKMEQFRSCNIKSTMLPQAASATPNQVVVSSPHPVSTLSAKAKATGTNRSNAYKKRKAASPPLSGPSSSFHTQTLTQFCPGSFIALPISHEIGDSEEEDGESDSHKVVGSMLDKFPEEVGDSEDNDDDLSLLPAEPVHQIQSDIDDTSYILSSPPRNSPAPRTQSPLSNSAAHDENVNQDNAVQAHSSVPQTPTKGSRTEIPSSQPSPFTPITTRYNTTLDSPSLVRSRSMNSGALSDHKCLFSQASVLPKVSRFPSTATIQDSFTTGTSEGEAQASPSRHASLSSIHTRLSPNLPSRAHAPTKSQLQIKGLDKHITEVPASESGSSSSAIGSHREQRDILQDDIETQDGSGGEEDPTVIPDSEDESVTFLINNRITIELLDSESNLGRGAQNTNHEYSPTSKSLGVSDASSLSSVPSVLEDFLSSSSLQPPTDKPVSSSPSPILSVSPIHLPSESERIVAQDSGDGNSMSDITNSEGDITAIPPSPKSPKLSILEPPATPAVVVAATQTQPEHHKQFYETLGDYPLDQKEKGESNAFMPKAQIQTQEDVYGLGAETQAIMHMLASDHTAMPALPQHSILSHSDESKKPKTRKRAMFATSSPEIMPMRYYTPTPSLSQGADQNQNQQLVSIVHSSQSQYLQDHDYTAAGSQRVALHVIQAMEHPTNRTDIFISIHPQYVAQIVNGTKNHEFRKYQIHHEVVRMWIYETRPECQVRYLACIGPPKQVGEIDDLRGLGNAEFNNGDEKSKFAYEIMQVYELNNPQSLAVLKEKGWLEAPPQKYIFIAPAVSAQLLANLRHRIQPQPEEENDGCELFELPSISMPSQKQPDDSAQNNESSSNQLLSLSLTSEDDDVGLGQSTPSQERFRTTDTVSLQTSNADSKGTRPEAQTDVYHSTSLKAYEFKRPELPSWRRPPSSAPSAQTTIATSSISAVSLGIGANAGMSFSQATTASQSSTPSSPLLNASPRNSRAGTRSMRSNGGTTGDSMMNILRTENSIANSTASGNSGPNSSGNSNSNGNSNSNSNNSNALSQMPPSPLLSSSQPNFNDIESPSPLLATTPVSEPKDNPVSGLGTEPSPGSLGLSQLFSGGEFALPRSLIEDQEPPPVISDSEDEGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7U1</accession>
    <name>A0ABR3Z7U1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Signal peptide peptidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_002860</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase A22B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000060">
        <property type="protein sequence ID" value="KAL1896267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007369">
        <property type="entry name" value="Peptidase_A22B_SPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006639">
        <property type="entry name" value="Preselin/SPP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174:SF23">
        <property type="entry name" value="MINOR HISTOCOMPATIBILITY ANTIGEN H13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174">
        <property type="entry name" value="SIGNAL PEPTIDE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04258">
        <property type="entry name" value="Peptidase_A22B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00730">
        <property type="entry name" value="PSN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="109"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="283"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="436"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="464"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="33"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="508"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="508"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1896267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="558" mass="60608" checksum="E14172E91B461FD8" modified="2025-10-08" version="1">MPSSSEITSIVDLLIQLVGGASLCIYIGAHSSLARPPSASPHSPTRSTASDSESDSDDDDADEYDPALQAGLDASDAVLLPILSALVLYGMYCLLKYLDDPTLLSRIVRGYICIVSLVSVTATLSQALLLATSLIFPRIWRARDGTLYEVCPEKSGHIRLTQSGLGGSMYRGVVGPLPFGICGETIGSQGQALSERIPAQYLWALRALLTQKWRLSINVTRGLPMRERVTLRIQHIAGLVLAVGTVLGYHFTNSVSLSNLIAVCLCHMTFSILSPTTFVTGSLVLMGLFVYDIVMVFYTPLMITVATKLDAPIKLVASTAGRKGSMLGLGDIVVPGIVMAMALRFDLWRHYAKKIKYETVELKTTTASPSAEELADPTIILTSQQRTMATKARYISVADKWGDWLWTLPSIFGRSSSSVMAPLPLSLSGTQFSKTYFAASMIGYVAGLLAAMGCMLVFKHGQPALLYLVPAVLGAVWGTGTLRGEIGLMLKYTEDGSLDTKEGIVEVDAEGRPVQSEEERKRNEEKKKDHDMKTRTRKPGKDILVFKITQVASKTKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8L9</accession>
    <name>A0ABR3Z8L9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Endosomal spry domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002526</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000050">
        <property type="protein sequence ID" value="KAL1897001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="314"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="391"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="410"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="491" mass="54503" checksum="05A4CCA83205CFEE" modified="2025-10-08" version="1">MSSSLELLGHKAHSLLARTLPARAAVRILTDEELNPLGPLKISREMRRQESDENLKNYNPGEGTIDPKNINQVAMFIFFGFLAASIVVGMIWFFFWAKNGGFTYHDDDWEEYVSTVLRRKGPNGTILSNATKSTDLGGGSIYHNYYGDNRTEMTENTGLSGSTISGITAGASDLPARQERKRKIEKRKREKKAAKERAMNTGEDAVLMEQEAEAEAFANLHQYRSERPARVGGMNRPADGSEWEGSTIPTESAVSASLLDNQQPTPTNSPQKKKAPGIRKVYSMADRNRRTEEENLKAETRALHRQNRTSALRGGASDVSASTDAGDSTTTASTASEGLRRSYTYQRSGAPRSKSKRRPRSDMAQTQISSISEESRTTQAGPGPASSHWVPPTEISSSGPTSSTISGTTAQTDSSTGTKSYYHPIPELRATRDPQPDSAPPTREPSRRRRESREESSRRRTSQSRPRTQEEERRKSRGYRRTRQSDHDDVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z926</accession>
    <name>A0ABR3Z926_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Alpha-L-rhamnosidase C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002492</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000049">
        <property type="protein sequence ID" value="KAL1897171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021369">
        <property type="entry name" value="DUF2985"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35872:SF1">
        <property type="entry name" value="ALPHA-L-RHAMNOSIDASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35872">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07110)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11204">
        <property type="entry name" value="DUF2985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="219"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="405"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="467"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="487" mass="53575" checksum="4C5CBA7ACAF6EAD9" modified="2025-10-08" version="1">MNSPHASTPGGNEPFPELPQATTTTTPIDSPPEELSRFPSSGLASTIRRMSKTFEESDIPPGFMAATGTIASSAVNPPSRRRSSVKSTDDNRSPRHGSFSRTISNDKATSIRQMPSAVLSAGPSTAMLSDVQEYPSGIESTPPHLPPPISTENGVEEAAIGTQESFKQVSASDSSEGKASNVDFLVRSDTATFDNGYHFPPSYTAWESTKHFAIVLWRYFLTPVGFLVVFYGLNVIAWGGMLFLLLCNAAPAMCHPSCNDINSPRRKWLEVDQQIINALFCVTGFGFAPWRVRDLWYLMQFRLLKRFMGLQRLAGINNSWFRLPGSQSLPPHIGPDNVDEWPAGIDPLVVPYPSKSTPRAPLTGQRALPTTMWKMDTLVWMNFMNTIFQVLLSAFMWGMNRFDRPGWVTGFLVSMGIGTAIIGGLLIFLEGKRVKGIEGVPLTDRDIAKLDHDKELGISHYNNLSAKKPKVSGEKSRLAKRTSSSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z985</accession>
    <name>A0ABR3Z985_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000054">
        <property type="protein sequence ID" value="KAL1896727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="294" mass="31453" checksum="3D57AD2FB59E79F7" modified="2025-10-08" version="1">MALQLSDVKVLRTAVLDEHNRWFMYFQTPDGAHTYRSSMSFNEQYDPGPYGWLTSTLASQSKSWPAVSASLGPDDSLFIAMASGECSFAPGLPPTTAKAVRRVRAGQTLQVAQGVHDAHVILHGRRKTSWSLGDGYPVLADILEKVRGRYHVSFVALNPWKHNEFFLMIEDKVCFFHVAPAIHANIVAALSAAGIPANVVRRDGTQGLRSGMDKSMNTGMSEDRNSYGDGRASGKISSSTRAATTTTTTVCATGIGVDRDELCGAIETAIMGYNFMNLAGGAAPVAAAAGCSVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9H5</accession>
    <name>A0ABR3Z9H5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_002515</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000050">
        <property type="protein sequence ID" value="KAL1896990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF84">
        <property type="entry name" value="METHIONINE SYNTHASE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="6">
        <location>
            <begin position="308"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="171"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="728" mass="79254" checksum="FF0094C029B3DA1D" modified="2025-10-08" version="1">MSAVEPTHSLLPKSNSCCIPQEPSVTSLAPSLTYSEESEIDEDPAPGSASSRQRRASTRLISQNAADIERITGQTTAELVSRCCGGGCCRTNDGAAQNSENTRHPGTECDQIPLPDNDAFRSLNLKINDIPTKLTGLCDLPEQTVYLLPLPKDNAAIPRLQASESGITAVFQPNKDASTTNTPETPPAYASLTANTPNQVSSASGGVAGVGPLDTPAEMIAAINSIEAASAPATVSGVNASNITYEDDASSSVVSDASTISTAMESVSTLNDDVQEVKTETQKSSSLSLENLDTSIQPPSFVQPHPPYHVFPARLHNARELTRNGAEKRTYHFDLDVTNYPDESGVDFRVGGAIGVMAPNETSFVEEIMDILCIPRTLRDKPTLLKTTNGRWPTVWGDEKPRELVTTRRDLLTWCSDVQSYPPTKPMLRLMAEHASDASERRILEYLCSNEGQGVFCEFRTGPHVTVSQILEAFPSATPPLDHLLSVLQTLMPRFYSLSNDPHESFSMTTDGKDARRVIEIAVTVHESHDWKKGARTGVGSGFFERQARKYIAAQEAGVASPVVYIPMFKGLMQNPLAKKFVSDGPMLLIGAGVGIAPFRGFVQRRLKTANCANKVWVLQGIRDSLVDEIYSGEWGIHEEEVKRVVESRRGTGRYVQEEVRAQADLVWYIINSVDGRVFVCGSSRGMGEGVEEALVEVAMDKGNLGLDEAKNFWKLKNEAGQYIAETW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA19</accession>
    <name>A0ABR3ZA19_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_002352</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000045">
        <property type="protein sequence ID" value="KAL1897496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="133"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1897496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="192" mass="20784" checksum="B2B7FA7519A2CF8E" modified="2025-10-08" version="1">MAFQPVLDFSDRARFPNFNDIPTIEGSHVLLGTYKENMSITRPTYILEDRDKQSFAVTFMIANDSPVQPKFKKGAAVAVCGLARQEPNAAAGETKKSACIRVRAGEETRVVGLGVSLDRILATSAASPLTASCAACGKPEGKIEGMKRCTSCGWVKYCGKECQMEGWSAKGHKGDCKAFRLLQAVLKENKMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA49</accession>
    <name>A0ABR3ZA49_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">pyridoxal 5'-phosphate synthase</fullName>
            <ecNumber evidence="4">1.4.3.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PDX3</name>
        <name evidence="11" type="ORF">Cpir12675_002321</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxine 5'-phosphate: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.5" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000044">
        <property type="protein sequence ID" value="KAL1897533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004733">
        <property type="term" value="F:pyridoxamine phosphate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000659">
        <property type="entry name" value="Pyridox_Oxase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019740">
        <property type="entry name" value="Pyridox_Oxase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019576">
        <property type="entry name" value="Pyridoxamine_oxidase_dimer_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00558">
        <property type="entry name" value="pdxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004231">
        <property type="entry name" value="PRK05679.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10851:SF0">
        <property type="entry name" value="PYRIDOXINE-5'-PHOSPHATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10851">
        <property type="entry name" value="PYRIDOXINE-5-PHOSPHATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10590">
        <property type="entry name" value="PNP_phzG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="PNPOx_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01064">
        <property type="entry name" value="PYRIDOX_OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyridoxamine 5'-phosphate oxidase N-terminal" evidence="9">
        <location>
            <begin position="87"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridoxine 5'-phosphate oxidase dimerisation C-terminal" evidence="10">
        <location>
            <begin position="241"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF10590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1897533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="283" mass="31177" checksum="F6B17E927A5BC522" modified="2025-10-08" version="1">MALHSAPADKLIFAPTGDGAQGPGQAAQFTLGKLIRSDLQSTPTAQFHAWFKACSQPSPLPPSAQVLSSTSTSTADSPFPSTHVTPAVSHPETCVLSTASLPSGRVSSRVVYLKELDSAGHFVIYSNFGTSRKAADLATNPHVSLVFWWEPVQRQVRIEGVAQRLSAAESQVYFDTRARGSRIGALASRQSQVLDKQESGAEFGAEGEDNLDDGRAQLDEWVRKVEQRFEGQDKIPVPEFWGGLRIIPDHFEFWQGRESRLHDRFVYDKDEQGGEWKVKRLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA82</accession>
    <name>A0ABR3ZA82_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000048">
        <property type="protein sequence ID" value="KAL1897224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1897224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="397" mass="45614" checksum="17483F3D7FB6BAE1" modified="2025-10-08" version="1">MSSSTIHFQDFMSVLPPECCDMVWQFLPSDALHSCMLVSKLWYSDVVPLLYKDVVLECDNYFFQKFSQAMRNSPHLALMVRSLTFTHSDRLAKDIDYFMVKCIEPLRNLQYLRLDGAFSGFGKRLAQMQERGSCFPHLKELHLGTHGQMLAEVSHVWKLPALQSLQVVIGDYTRYEFDFSSWPMAGNLKSLSLSCANIDYQRVSSLLSLAPGLCRLDFVDFRDVTEQESAQDYSKLKLEQLAYLECLMLGVITYSKMHNVDFMDILPERGHLQPITNLKRLHKLDISVNSLLGWYPEEAPRISDVIPTSLTTLTLNDDCVGQCGYKWTEKQLIARLWDLLRDTTTGNTNVQTIKFGPLGDRWTGETLDELHQVIKQSGSQFEEEMVEEHGQYLKIHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA87</accession>
    <name>A0ABR3ZA87_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutamine synthetase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_002354</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the glutamine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000045">
        <property type="protein sequence ID" value="KAL1897498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="entry name" value="Glutamine synthetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.10">
        <property type="entry name" value="Glutamine synthetase/guanido kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43785">
        <property type="entry name" value="GAMMA-GLUTAMYLPUTRESCINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43785:SF2">
        <property type="entry name" value="TYPE-1 GLUTAMINE SYNTHETASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51987">
        <property type="entry name" value="GS_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GS catalytic" evidence="5">
        <location>
            <begin position="118"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00021364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1897498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="443" mass="49998" checksum="ECDB3C7C67FB03E3" modified="2025-10-08" version="1">MTFTNSSKTAGIINELKYTSPPIEYLRIYWNDLSSIPRARVFPIERILDALNNKEFRVGIASAWTGLMPDDNYIGDSAAGEFDLFPDWSSLRIGPRHGHASVQGEFRNKDGSQSRLCPRSELRRVVREAEAIGLDFRIGFEMEFMILERDLSGNLTSKYQGSWSYARALDTGYARRVIEPTIKKLKESGIKVEQYHAEAASSQYEIILPHKPPTEAIDNLLHAREVLHATALSEGLVVTFHPKFDSAKCGSGSHVHLSLCQLNNNKSAYESFYAGILSELPTLLAFTYSSPASYLRMRDFYWAGGSTVAWGKQDKEAALRVIEDSHWEMKTMDGMANPYLALTAILTAGRLGYMQKMKLSMDECTTNDVIKQSPIAANNDLDESRRPLPRSLKDALGILKESSLKDSLSPSLIQHYIKVKEAEIAMYEKMDEDEMREFICCRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAC3</accession>
    <name>A0ABR3ZAC3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">26S proteasome regulatory subunit 6A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RPT5</name>
        <name evidence="8" type="ORF">Cpir12675_002566</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000051">
        <property type="protein sequence ID" value="KAL1896985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 8" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="7">
        <location>
            <begin position="242"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1896985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="462" mass="51344" checksum="2DD89933EA22C778" modified="2025-10-08" version="1">MSTLEEIDDLDRHDRDDKDNKNQKPPGDGNGKSGEDDTDMKDAEPEQEEILDQEILSLSTQDILMRKRLLDNDAGIMRSEHKRLQHEKSSMLEKIKDNEEKIQNNKQLPYLVGNVVELLDLDPTAESQEEGANIDLDATRVGKSAVIKTSTRQTIFLPLIGLVDPDKLKPADLIGVNKDSYLILDTLPAEYDSRVKAMEVDEKPKESYSDVGGLSKQIDELVEAIVWPMKEAERFTKIGIKAPKGALMYGPPGTGKTLLARACAAQTNATFLKLAGPQLVQMFIGDGAKLVRDCFALAKEKAPSIIFIDELDAVGTKRFDSEKSGDREVQRTMLELLNQLDGFASDDRIKVLAATNRIDVLDPALLRSGRLDRKIEFPLPNEEARAQILRIHSRKMEVSDGVNWGELARSTDEFGGAMLKAVCVEAGMIALRTGKNKVGHEHYVDAISEVQSKKKETVNFYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBG9</accession>
    <name>A0ABR3ZBG9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CPP1</name>
        <name evidence="8" type="ORF">Cpir12675_002499</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000049">
        <property type="protein sequence ID" value="KAL1897178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd14521">
        <property type="entry name" value="DSP_fungal_SDP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159:SF519">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE MPK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="6">
        <location>
            <begin position="275"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="7">
        <location>
            <begin position="375"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="739" mass="81202" checksum="EA43B513D37B6DA8" modified="2025-10-08" version="1">MQDGFLQPPIVLSQSQHKHRDSSSTQNSDYSDSSPTTTNSTSGIFDPVVTCLDSPIVLSPMKPFSSLELGLPAGMSMLSVNDGRSTTEPMRPKTSPTPRRARNMKNLSILPPLGPSPVSPLASEPSSPSFVKPFIPGIKRKPSNLSLNTNAASLTGQQHRDTYVSPVSRPILQRRGLKHSASTPQMLHGLKSSTFAPANGMTFPTVLERNESGLSEILRPSKLGGILPIHDVSIPEEETQITTQVAGRGALDADEHLRDESEKHEDLKSPTYPDGPVAIYDDDVYLYLEPNAEEASRFDVVINVAREVDNPFAKSDDKNSSPQPDTAMSNASFSTAFEFQLKAGESPTTPKNSKPPTRIPVYIHVPWDHNTDISADLMSLCERIEQFVKLGKKVLVHCQQGASRSASLIIAYGLFRNPDLTVNDAYHAAQSKSRWISPNMKLMYCLQDFQKEVSLRHKPLHTARHQRTGRSPTKHRLTLSADVAGSSDPQQPLTAPLTNDTSFTAFGMTGMHFRGNSCPSTIHIDSGPSSAPSNIGSFQPQDSVRDYHKFPRFPYDKPESSSTKPSFPLQVDGSLTNELPETLENVSTHRNTVNFSRPITWSRRPPSPRPLRESPHVKNVEQKAAFGSLPLNNTSLVSHTPDDFFDDTCVMSPRTEVMTSNPLRDVLRETIPPASSTAKTIFTLIESSSTPYPKGVFSPTKVSFPGHIHEEFNLPEISDPRSPLTKGEAPIVRSIDELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBJ2</accession>
    <name>A0ABR3ZBJ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Component of the polarisome</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SPA2</name>
        <name evidence="3" type="ORF">Cpir12675_002128</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000038">
        <property type="protein sequence ID" value="KAL1898041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013724">
        <property type="entry name" value="GIT_SHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039892">
        <property type="entry name" value="Spa2/Sph1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056439">
        <property type="entry name" value="VBS_C3G9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21601:SF0">
        <property type="entry name" value="PROTEIN SPA2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21601">
        <property type="entry name" value="SPA2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08518">
        <property type="entry name" value="GIT_SHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23742">
        <property type="entry name" value="VBS_C3G9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00555">
        <property type="entry name" value="GIT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIT Spa2 homology (SHD)" evidence="2">
        <location>
            <begin position="132"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="GIT Spa2 homology (SHD)" evidence="2">
        <location>
            <begin position="185"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="416"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="690"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="711"/>
            <end position="720"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="756" mass="83844" checksum="5F2863661FC498FF" modified="2025-10-08" version="1">MNTRNAPISPVSVGGNDWSASKYASNNSDSNNPNTNPNAGANSRAQLATPPNSGGVNMDTASFPQRPRSPGNPSPPPSTARSSTVTNMYGRRESGWSAREEQNIEVILGEHYLAFKAFLKGREARNQSSNNAKDKLIRLTATQFYELSTDVYDELNRRQASARNPQSAPPHLLAQQNFHPKRNNARQTLSSIGPPRFLNLAIDVFNELEKRFPRFIEGDFPPRIGSPLSNRGPPSRTGTPVSGAYPRSQSRMRRPSDASSVRGGPPGDPYGIPPSPRLPEGEFPRPMPKQFQSNTIVPNKSTMVEEDDDGNEGSEEDKKIIEDYQLQVEDLKAQIETLTAETQKKDEELKNTLDGERSRSTAANLEKKEWSDMRLDLEDKLAAAQSLNSRLQEDIEHMRRDHEEEVRTLRDQIEAGAQASRDQASPELQRENDELRAELQQQAALIEEVRAQARESLQEMRMLSKQSDSSYERIQAMETSNEQLQNEVREWQSRFVMAKAQSQDLRASSNGLPMVNDISKQLREQGLVDDNGIIRDIHVTRFQMSIDEIMRFSHSNDFERVNDSMKMVVSNVRRMTKDVDTTKPINEQLGHQLGTLKAKVAGSANNFITASKSVGSSAGLTPVSVLDAAVGNLSLAVLELVKVARVRPTPLGELDEYDDGIMTPVDSSGYFSPDRQTSSQSGYDIHHTQADSYGVNNLPPPPPFAGLGRPSSETSSTYSPVASPRESVEPSYGRMPMSKMSNGYSNGYGHDEELKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBJ3</accession>
    <name>A0ABR3ZBJ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_002134</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000038">
        <property type="protein sequence ID" value="KAL1898045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024586">
        <property type="entry name" value="DnaJ-like_C11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052243">
        <property type="entry name" value="Mito_inner_membrane_organizer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44157">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44157:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11875">
        <property type="entry name" value="DnaJ-like_C11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="691"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="4">
        <location>
            <begin position="133"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="309"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1898045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="856" mass="94875" checksum="1D76DF264EACC4BB" modified="2025-10-08" version="1">MPSKEPSSSGRSKAGRSSRRSERSNRHGTSSRAHGAANEDPLYSNSPYQQSVRAAESRFSLTDQFATTAREFEFGFDDASSVFTKVTDVADNHPDPLPPYNDEAEGPAAVEDIVGPRGAWEDVEEDFDYVDPSHYDILCLPRNSALTQDQIRRAFYRQFMLLYPEAHANKYRAMAANHFFKSQQAYETLMDPQRRAGYDVLGEDCEDAEALVHGHYDSAVEGKLRARMQQVVYGTSEVGVRIDASKLYNQLYRQLSKGRTPTVANLAQSMKPLDYALSQSFTVGVPVHRILPLAQLRAAKKRLGGMIAKLRPDKGKAKSKKRSRDREQDKASAAAESSNYYMAIPTVTVAGSLYGLVDGLTQANVSSSLLTDRVQPLLPLTIPRHRIVQLGELKCTPLVAVRVRQEMIHRVRAAERRESAVGTSSSAAVAGSEERWTKSAIEVETDVIPERSLTARVSHTFLLPYSSVPLNIEASATNGRYVTGGIPRLGMGMYRKIGPGTAFFRADSGDWRFGNGRVCNFFGQFAKESKKWFYADFQFPLKTTPSIEIGYKTTPCERWTTTNYADIPRGESGIRGMDRESSFAGRGSWAMSVSAMPSDVFAGYLRYSRDIPYLAPTQNPSRIEAELCGSNSADYYLALRNLWQVGNFARLGLEVSVSAHHVHLSLYWARLSHAVSLPVLVAPRTMISDKMVAWGAVVPFVTVALGQLGCRWLNRSRVAKKMARNQEAVRAYVDQKRVDAEEVEYLIGGFVETHQKREAKKGGLVILSAKYGVKEGTGSNAVWGGGEVADVRVAVAALVDGDGRLEIPYGVRKSHIPGFWDPMPLQEKVLHVRYMYRGREAVVEVRGKEGLVLPPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBK5</accession>
    <name>A0ABR3ZBK5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_002076</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000037">
        <property type="protein sequence ID" value="KAL1898058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF11">
        <property type="entry name" value="ZINC FINGER PROTEIN YPR022C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="370"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="281"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1898058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="489" mass="53240" checksum="D7D2849B25494BD1" modified="2025-10-08" version="1">MDASQMSYFLCDPKSMPMQVFHGIPMSMSMSMPMTPIFSRPNSSCSPQAPTLYSNGSSMTPVTSPQPMMSKPTVVVNTEFGTSPTTPPLSMSGSAMSSPNGDMLQTPMNPMFSGIEIKDMPPPWVSHVSPPHTPSDFMSSQSSAASSFTTCPSLSPSPTPDVSEFLDPRNLTVLVTSPSSAVIAPMAEDMLNEQFSKADMEGANFEIEPTVEVVEDLSLDLEDEAEFNFARMNGSLDSFRRPRACTGSSVLSLGHHFFDSAEINFDDTSFDFMTNTPEVDHDVHRNKKARTSPGPSSVTMVGGLASPETTDSRSSTSPVADNSSSLEVSSPEEMSTMASPTCSASPTAVAAPSSRRGRKQSLTEDPSKTFVCDLCNRRFRRQEHLKRHYRSLHTQEKPFECTDCGKKFSRSDNLAQHARTHGSGAIVMDLIEDQEQQQHMYNPLLAATGQEFSPYGKVMVQMSTDMLATAGMVQADVMDGGKKKRKRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBU2</accession>
    <name>A0ABR3ZBU2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000040">
        <property type="protein sequence ID" value="KAL1897785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1897785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="213" mass="23972" checksum="BF569B59489CB97F" modified="2025-10-08" version="1">MANTRRKDYEVFQKVFSILKTVLGGAIQKTLAGSELPIAFQASAWDSHPGQFRHGKRSIWKEVNPAIVKSRVNKDFFEGKEVVTQAKTAQTGSAITLTGGQGLRKEGTLELIRNYLDVSSLEKETVWEKYIVKNVPRNVHHVTGKGSEIRRTSLEDVRAEIQKAFGGELKILEFREYKDEPQVQGLRVAILNPERATRTIEPLGSERAVKKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBV7</accession>
    <name>A0ABR3ZBV7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Serine/threonine-protein kinase M1</fullName>
            <ecNumber evidence="8">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MEC1_1</name>
        <name evidence="8" type="ORF">Cpir12675_002236</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000041">
        <property type="protein sequence ID" value="KAL1897737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1740.10">
        <property type="entry name" value="Zinc finger, PARP-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017956">
        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001510">
        <property type="entry name" value="Znf_PARP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036957">
        <property type="entry name" value="Znf_PARP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02178">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00645">
        <property type="entry name" value="zf-PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00929">
        <property type="entry name" value="ATHOOK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00384">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM01336">
        <property type="entry name" value="zf-PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PARP-type" evidence="7">
        <location>
            <begin position="7"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="105"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="130"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="277"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="341"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="364"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="380"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="403"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="425"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="464"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="503"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="524" mass="57548" checksum="3D90305C3DBADFB0" modified="2025-10-08" version="1">MPQYRVEISPNNRAGCTDTVCKKSASKLTKGELRFGTWVEIEGRGSWKWKHWGCVSGQQMQHVQEACMEDDTLNLDALDGYDELTDDHVKIKAQRCVKQGHIDAEDFKGDPEFNKPGMKGIRGRATKKKLAMEKDGEKVQEDGEDQASAQKKVQEEETPMPEQPTTKKRGRPPKAKPAAENCDLDGQKPSPAKRGRPRKSVESVPAVVEARDPSAGSRAADTQEMMAPKKRGRPSKRPIEELADAEEQEKTAPAPKKRGRPKKVVDEDVNAEDAKPTPKRGRPAKKAAHDESSVDEEEKPLPKKRGRPSKKAVEQQPQPQQENTDEEEKPTPKKRGRPSKKPVDEENPGEEKPTPKKRGRPAKKVTEKDSGAAEKDKMQMSATKTPSRPSNKKNAEPKPAENSTASTPISTTTPTTLARRGRPKKSVEMVHDQRPEAKGQPQEEAKSTPAKRGRPRKSAGSNDTSTPLPASASASAPASVPVSAPTKESSTPNKTAVGRGKRKPVEEDSAKASEPQKRVRRSIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC42</accession>
    <name>A0ABR3ZC42_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002172</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000039">
        <property type="protein sequence ID" value="KAL1897827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="199" mass="21559" checksum="BEA19512D499DBB1" modified="2025-10-08" version="1">MAVTTLIPFEIFPTCVYDCGALYDANGGCVPPGFREASPDIYTACFCADPRVKKFSSQSTGVCDNACIGTPEGLASVQTWFMSACGVTSESTTSTTTTSTLTGTEGFASDKPKKVYDSWIDGHWKWVAAIVSIFILIVGCWIGACIWRRAYLRKKDRMYELGKGIPTNSTTNFPVADASQVGVAQSSNVEKIRKWTGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCB3</accession>
    <name>A0ABR3ZCB3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">mRNA-decapping enzyme subunit 2</fullName>
            <ecNumber evidence="11">3.6.1.62</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">DCP2</name>
        <name evidence="11" type="ORF">Cpir12675_001953</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nudix hydrolase family. DCP2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.62" evidence="11"/>
    <dbReference type="EMBL" id="JAWDJO010000034">
        <property type="protein sequence ID" value="KAL1898328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140933">
        <property type="term" value="F:5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03672">
        <property type="entry name" value="NUDIX_Dcp2p_Nudt20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1050">
        <property type="entry name" value="Dcp2, box A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007722">
        <property type="entry name" value="DCP2_BoxA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036189">
        <property type="entry name" value="DCP2_BoxA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044099">
        <property type="entry name" value="Dcp2_NUDIX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23114">
        <property type="entry name" value="M7GPPPN-MRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23114:SF17">
        <property type="entry name" value="M7GPPPN-MRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05026">
        <property type="entry name" value="DCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01125">
        <property type="entry name" value="DCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140586">
        <property type="entry name" value="Dcp2 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="10">
        <location>
            <begin position="98"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="294"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="358"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="463"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="505"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="744"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="832"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1006"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1052"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1088"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="368"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="378"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="420"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="438"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="505"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="654"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="751"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="764"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="834"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="884"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="900"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="948"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1052"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1094"/>
            <end position="1106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1898328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1113" mass="122735" checksum="0B3ABE5B453E924D" modified="2025-10-08" version="1">MALEQSKLRTLEDWLDDLCARFIINLPAEDLSSMERICFHVEEAQWFYEDFIRPADPNLPTLTLRNFCAMIFKHCPLLADFPVEAHEKAFENFMQYKQRIPVRGAIMLNEAMDHVVLVKGWKKTASWSFPRGKINMDEDDLDCAIREVEEETGLELREAGLVPDDEAVKYIELNIREQAIRLYVFRNIPMDTTFEPKTRKEISKIEWFPLSELPTFRKKNNQLHEDPANSLVSAAASSANNRFYIVAPFLGPLKKWVQKQKRMDARRQGTTADMSHLIPSNIPEEAYAEGLETAHPYNHGDNDYSYGQQQQQQANLDDASHDLQRLMNLESSGNPAVHISAPVANSTEMSDRLMSMLKIGGVGGSPDSRGSQGSHKPQQSFGAQQQPQQHRQPQQHQNQQFQQHQLNQQHQLSTEYSHHGGTSSHSNLEPSQPPLIKQTPPTQIHHPQPIPPQVQKANLDQGLLSYATPPPTNGKPQQQGPSYSLQTILAQTRLQQQQQQEYQRRAQQQVQEQSQQQAQDQPQQQQQQHQHQQNLGQQQTHLGFPGHPDAQQQPQHQPMNGPGPYSQQHQTPELAIPQSHSQPQSVPGYEGDQYGSRPVSGQYNVNPPHSAHGSHVSGGNLSNHTKGLLGMFGSETSSGAQPIPIPAPQHQQATPETMPQRSWPNETPEQQLARTQTLNGHGQINGNPDGTGHMVSQTSASQIGSHPSHMDPMAMHNGQAILNGMMQKNQQHGMSSDKQRSALLDMFKGGPSPSSSISEQQQPMTQPDSYRQSPMDGQSFAGPRHNGGGDSSVQNLHNAMSGLAFQGGVQQSSSMSNPTYVRGTVSIESPMPLLQSNSISPSVGSQSRHSQTPYNFDRSTLESTGPNQSAMASPPVINGAAGSKRAESTPEQKQRLLSLFSGQQQGHPQQPQQPQQSSSFHQQSPGQFHQQPQQHTMALHARQQSSPQQHYAQVYGQQNQQQHAHIQSHMHYSGSHQPQGQQPHPLSQSQVPGTEAVYFDKAKGPEVLQPRGASGGPGSAGSGPVHMHRQPHSQQPQQYNTMEAFHRLPSTASAMSDGSHPSNGGKNTPISPADRSFLLGYLQSAMTTTPAETSGAPSSGVGAAAATQPAGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCH3</accession>
    <name>A0ABR3ZCH3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glutamate carboxypeptidase II</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_002127</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M28 family. M28B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000038">
        <property type="protein sequence ID" value="KAL1898040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08022">
        <property type="entry name" value="M28_PSMA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02121">
        <property type="entry name" value="PA_GCPII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.40">
        <property type="entry name" value="Transferrin receptor-like, dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039373">
        <property type="entry name" value="Peptidase_M28B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007365">
        <property type="entry name" value="TFR-like_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036757">
        <property type="entry name" value="TFR-like_dimer_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10404">
        <property type="entry name" value="N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10404:SF46">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04253">
        <property type="entry name" value="TFR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47672">
        <property type="entry name" value="Transferrin receptor-like dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="4">
        <location>
            <begin position="209"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="6">
        <location>
            <begin position="402"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="domain" description="Transferrin receptor-like dimerisation" evidence="5">
        <location>
            <begin position="690"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="271"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="290"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="834" mass="92323" checksum="7372CC9EF970F349" modified="2025-10-08" version="1">MTSESTPLLGRPHATATGRPRRSRQLSGCAIFVRWVMIGCSSMLLTAGLVLVVLSLLLAAPYGPDHASVIDTVKSGLRHNKAHSIPYHELQDILINTPSAERSEEWSRYYTDGPHLAGKNLSQAVWTRDKWQKWGLDSRIVSYNVYINYPEDHSLVMYTKTTNKTASTERWKVVYKASLEEDVIPEDPSTARPDRIPTFHGYSASGNVTGQFIYVNYGTYLDFEDLIRAGIDLEGKIALVRYGGIFRGLKVKRAQELGMIGVVMFTDPGDDGEVTKENGYEEYPIGPARNPSSVQRGSTQFLSIQPGDPTTPGYPSKPGAPRQPVDKAIPSIPSLPISFRDALPILKALNGHGPAASDFNSAWNRNLGLSYLGVKYNIGPSPQDTVLNLYNKQKYVTTPLWNVIGVINGTIPDEVVVIGNHRDAWIVGGAVDPNSGSAVLNEVIRSIGVARAAGWKPMRTIIFASWDGEEYGLIGSTEWVEEYLPWLHVTSVAYVNIDMGVGGPHFGASAAPLLHQILRNATASVASPNQTVPGQTVADVWDGRIKTMGSGSDFTAFQDFAGVPSLDMSFRHDTHSAAYHYHSNYDSFDWEKNFGDPSFLYHRTMAQIAGVVIAQLTDLPVIQFNATQYADQLSLYLDSIESKFAVTAPHSFTGLAHSLGLTDDDIHFVQRSVTSGTGQTTGSLEIFKPHFQQLRETLAELRTACVELDNDRAFVTNELAAHIPWWKFWRLAQLVVVMRRTNYRYKTFERSFLYDKGLDGRSWFKHVVFAPGRWTGYSGAVFPGLVESIDDNNFANAVKWANIINDCLKKAVEGARAAYVPRFDYSLFNVGSVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE71</accession>
    <name>A0ABR3ZE71_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_001848</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the ZNF593/BUD20 C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000031">
        <property type="protein sequence ID" value="KAL1898644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051879">
        <property type="entry name" value="C2H2-ZF_Maturation_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46095">
        <property type="entry name" value="ZINC FINGER PROTEIN 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46095:SF1">
        <property type="entry name" value="ZINC FINGER PROTEIN 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="94"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1898644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="119" mass="13520" checksum="D749C08F246ACA7C" modified="2025-10-08" version="1">MGGTFAKRTITKTRRKIRDLDQIKADMLSPKHLEQFKSSKAAEDLPGLGRHYCLECAKWFESEFSLIAHCKGKPHKRRVKALVEEAYTQREAEAAIGLRTDNKGPQPKPAHEDDVEMNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE96</accession>
    <name>A0ABR3ZE96_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001886</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000032">
        <property type="protein sequence ID" value="KAL1898421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="453"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="505"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="568"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="629"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="681"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="883"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1097"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1280"/>
            <end position="1304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="255"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="292"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="341"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="459"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="507"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="893"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="917"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1135"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1292"/>
            <end position="1304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1352" mass="145142" checksum="01D0D67A29C2F66B" modified="2025-10-08" version="1">MLGKLTRSRSLRTLRKAPPAIKDKERTKYTATVSDAGTAALSDNSKHIITNSSHPKARGTMVATDATVVMNPHSSAVTPTTKTVAGKADLTASRPSGRPVPPPKSAQAESETIPHGPSELALIPAVSVPRDYVSEVSNGAAENTPRSVSTRPRARTDTQALLRPKWGDQDRISLAETRPGAIAAITRSGASAKLMSETKKHQEPDRLEGTSEARLRSKFASFQNSAVPTRSRSMREPPSYTRSLHNRQAALDIEPSSNHSSASASPPSRSTSHSNNHSSHSLATPFASPPLRSTTTTTITSVSSRTRSISVIYTKPPSSVFFEHHPTVSPLSVTPLATAVSPSRQTSSKQTSSSTSSPNPTPSRSVGLRRAASTKQYDADRSKRYDLVSPLRLSPPDLEKPQLSSLAGQLKRSQSTSSVRRTTCITTSIDAIATAPLSSLNPTYISLLHPHQLNRDQGRPSTSSGESFTQPKISSLNSRLSSQHKTYEPIICGSAVAAQTGHINAKAPSTTEPPNSSTDSNMATIPTSSSVTSLVRPKHDFNKRVSRDDLYINTRTGKTTFRSYHVPIRGRVPSPKESPRSESPAVTLVRTQTPDSIGEVVDLPIGMALGSPTFVTVGSPAPAISLNSDVQSKAQRNNRAKDANTFPPMAPTSTSSTSAKIADAQHEVSPDKAKKWRFFGGRSRSRKHTTEHAQGALPKPGIPSVPVRQSSGDDARRPTTKELRNVEKMTKGTTRITPEEAAMFKPRKTLKRGPSVRLNNKMEISGPTSLQRVPTTVAMPGLDTAAAAATEMHHIDWQSGAQDSKSFGLLSLNIPDSKFDRYSIMFNGILQREGVCSSTLQSEPATSRHPGADDRALFLEKQASLLGRSQTVTSKPKVVEVVNKPQNKDMGRQLTSTRSSTFPIGVKDDDTPAVTASPMSPEQSKSPAFSLFPAAPSQQQKTTIPLASVLSGSTESLPWREVNQDSKEALKPLAFQHKQTQSPTEIGTAANNITDVANSPQKNSATEHQKVLSSRAANAHHISSSEVVPFVLVDSSKTVVPKNMPRLRYRNALIYEATEASPSTKAPVTATNLLHALSAAGMTSDATVRAISNDLERQASTASTRSDKNPIVLDNTNAFPQPPAARSANKKSAYVPSSSPIRGPTQASPIRHMKVQTHNIRNEPHTQSESSSVSLKLQTNQYRSRAPAQPFLEAKFEEEPLPHSSPTKPMLPMLRDTKPSVVAMMALSSESLQMQRSPLGPNTSVLVTESDDEIEVAAETAIPQPVPYASSVSAASGASSSATSLNTRQRSESNTTTSSKLTTSTQDEAEIALRNAVEVSIARQISVSRKHRQMLQKSGLIQISPTIKGGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEW1</accession>
    <name>A0ABR3ZEW1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">WD repeat-containing protein 82</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_001958</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat SWD2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000034">
        <property type="protein sequence ID" value="KAL1898333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037867">
        <property type="entry name" value="Swd2/WDR82"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19861:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 82"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19861">
        <property type="entry name" value="WD40 REPEAT PROTEIN SWD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="135"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1898333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="385" mass="42326" checksum="512A3FB6665883C3" modified="2025-10-08" version="1">MAATPMDIEGSHSSSANLARSGTSSMTHLGDIINTFRPTKLFRRDDIRDGRPVPYVLSLDFDDPGELLMTSESDETIQIYSVREGRHEKSLLSKKYGAKLARFTHLSSGIVYASTKQNDAIRYLATHDNSFIRYFEGHDGRVTDISMHPGNDTLISCSVDNTIRLWTLGTRQWVGQLFINNPYLSAYDPSGQIFAVGCPASGTVLLYDCRNFDKAPLGVFDVAAVGRHANHANLMRGWTKLEFSNDGKHLLVATNGDGHFLLDAFDGSLKAYLRLHRPGLGRVPRRLAPGDSATAANSANFVTPNAESSGDCCFSVDGRFVLASSGLDVAVWDTKNMGKEHPPIMEPTFVLEDGKRSAAVIAFNPRFNFFATADTEVTFWVPDPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEX5</accession>
    <name>A0ABR3ZEX5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_001824</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000031">
        <property type="protein sequence ID" value="KAL1898620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1898620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="189" mass="21322" checksum="68FB347665595326" modified="2025-10-08" version="1">MSDDPLFDIDGTERHDAYLLKKIHLPADIAPSCATDKSINTDPTASLDDNGGNNNADNFNLWIPTPSLFNMQHVVMTRRFTQGELIGIRHIIAYIDSLDWTFEATTLVLDTLLKHLPLPKYYNEFEPVRKYGWKIMNASILTAADVSDMTTPEFLCMVAFSRLPSWNIMTVLVDDLPLADRLSTMLESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFT1</accession>
    <name>A0ABR3ZFT1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 9">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="7 9">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_001683</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8 9">Belongs to the peptidase C12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="7 9"/>
    <dbReference type="EMBL" id="JAWDJO010000028">
        <property type="protein sequence ID" value="KAL1898931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09617">
        <property type="entry name" value="Peptidase_C12_UCH37_BAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.532.10">
        <property type="entry name" value="Peptidase C12, ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001578">
        <property type="entry name" value="Peptidase_C12_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036959">
        <property type="entry name" value="Peptidase_C12_UCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017390">
        <property type="entry name" value="Ubiquitinyl_hydrolase_UCH37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041507">
        <property type="entry name" value="UCH_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589:SF16">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01088">
        <property type="entry name" value="Peptidase_C12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18031">
        <property type="entry name" value="UCH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038120">
        <property type="entry name" value="Ubiquitinyl_hydrolase_UCH37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00707">
        <property type="entry name" value="UBCTHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52048">
        <property type="entry name" value="UCH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4 7 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UCH catalytic" evidence="10">
        <location>
            <begin position="4"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <feature type="site" description="Important for enzyme activity" evidence="8">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR038120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1898931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="305" mass="34693" checksum="728C8B408ED844FA" modified="2025-10-08" version="1">MSGGWNTIESDAGVFTYLLDNLGVKGVQFEELISLDPDMLAQIQPVHGVIFLFKYPTDTPYAPTSGPLDGTFDHAASETMFFARQTIQNACGTQALLSVLMNKAEEIDLGDEMRNFREFTLFLPPEYRGESLGNSDLIRSVHNSFARSSPFVDETQRGGEAEDVFHFISYTAHNNTLYELDGLQPAPIAHGPCSQEQFPSKVVDVLQRRVARYSSSEIRFNLLAMVGDQRVRAREFGDHEMLEREEKKRRDWISENSLRKHNFVGFSGEMLKLVVADKEAKGQYKEWVDQSLERMKSQQAMYKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFW9</accession>
    <name>A0ABR3ZFW9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">M7GpppX diphosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001374</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HIT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000021">
        <property type="protein sequence ID" value="KAL1899605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.40">
        <property type="entry name" value="Scavenger mRNA decapping enzyme, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008594">
        <property type="entry name" value="DcpS/DCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011145">
        <property type="entry name" value="Scavenger_mRNA_decap_enz_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12978">
        <property type="entry name" value="HISTIDINE TRIAD HIT PROTEIN MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12978:SF0">
        <property type="entry name" value="M7GPPPX DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05652">
        <property type="entry name" value="DcpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11969">
        <property type="entry name" value="DcpS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028973">
        <property type="entry name" value="Scavenger_mRNA_decap_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102860">
        <property type="entry name" value="mRNA decapping enzyme DcpS N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="330" mass="37818" checksum="2D1AB7C26CBA2F67" modified="2025-10-08" version="1">MNAAAVETLVPRFKLERTLNQDQSGRRIFLLGSIDDKPAILQLERSPFPSSQAYLASVPAGLARLSNLQHNDVYAWYLALAGNESALVDTASNSAGFHHDLKVNLIYPCTETHIKKYTKQPVRYVAETPEIYAKYVRPIMEEKRGEGRLNWVYNIIEGRKEAEDVLYRTPLGAEENLEGFLLLPDFNWDRTTLEALHLLCLVERRDIWSLRDLRKSHIPWLEDMRKRLVEATLATYPTIEADQLKLYVHYQPTYYHFHVHIAHAAAEPGHTQAVGKAVDFDTIIETLKSMGTWDDNKDPGMDSISINYTVGEASDLWERVYRPLKFGKDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFY6</accession>
    <name>A0ABR3ZFY6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000021">
        <property type="protein sequence ID" value="KAL1899628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="286" mass="31313" checksum="9D81068512F8CA61" modified="2025-10-08" version="1">MVSVDRYQAYAQLQELDLEPTGLKAVWVAQFLLMGPYLALLLSLVSREQEDLAGAELSSIWKTANIGLPIVIIILIICEVWHYISLTLTTRVMSLFYGIRAAWGFIIVLSHIILPTTVVGIPYGLCVGAIFIFSLCAGMASMKFALLGATDESVEFFDSEGCMYFQGRDLHCSCGKSLSSFASVSDVEKGKVDPDKVHGWVLSTKVSNNEDSLAPPPYANQQQMQQKMPPHQATLRAPMDKAPAGITPLAWSSVVAAHTNYSMKLDAVLEEARARKNMAHTQAKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGC1</accession>
    <name>A0ABR3ZGC1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">SEA (Seh1-associated) complex subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RTC1</name>
        <name evidence="8" type="ORF">Cpir12675_001463</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000023">
        <property type="protein sequence ID" value="KAL1899347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037590">
        <property type="entry name" value="WDR24"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46200">
        <property type="entry name" value="GATOR COMPLEX PROTEIN WDR24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46200:SF1">
        <property type="entry name" value="GATOR COMPLEX PROTEIN WDR24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 6" id="KW-0853">WD repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="158"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="252"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="424"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="743"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="803"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="917"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1233"/>
            <end position="1264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1283"/>
            <end position="1360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="424"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="441"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="757"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="815"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="835"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="917"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="941"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1233"/>
            <end position="1248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1300"/>
            <end position="1309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1899347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1360" mass="149864" checksum="028B1DB81B92C4E3" modified="2025-10-08" version="1">MYSRDSSIMRKLLGRGSSNVALESAAVPSGTGDGTWEFSPCSFPSNSHTKHYRGARYVAAAPILSIDASPNGKHLALSGRHILKTVNVEGTQFHEDIDLRAIITSQTGGKGTGISDQLSIQDVKWQSDSSIFTACAGGKIFYYDLNHSRGGAINPYPIQDNTRQITTLDVSPHRRSWLLSGGQDGVVRIWDMRAPPKGPAMEIVLKRRVQAHSESIRCVRWAPRDGFEFACSTENGMIFKGDFRHANFRMRINAHEGSCSSISWHPDGVHLLSGGMDQKLHVWDMTNADRRRRPKWVIHTPAPIGQALWRPSLWSATDNGRRAAQIAVTYDASSQRRHGRNMVHIWDLARPTLPFKVIEQFDMAPTGLLWRDQDILWAVGQDGNLNQCDVAFAPRVIDRQAMSTFAFNPNGEVMMFLDQRQSAPRNRSLHQSSLSAVDITSAASRAQRTSGGTETPSGYIGTSPQNVSLSVSRTDSDEDLTGIFLNPRRPSNSNRTRRTGTRAFPTGTTPKNPPFVAPHQDEDAMPLDQSMHATGDFIMTQGMAFSHTPFRVDPEMYRYLTFHYLTILQRDLPRKDENAWPLPRRIASILEQYGQVAEDARLFRLAQTWRILSHVTQILLHRRGEYHLQVRTGQIGREVSRTPAVAPVRLQAQAFLQSSTAVTTAFVRSGHAPEPAHSNRKQSSLIYQNSTPRDHSLNSARSLLSEEFENTSNMTTPRAHAVLDPVANDRTIGATPLSPVAEAPASFTLPPPAAYPPTSNSPRARLNSQPLSTTSQHSSDTHASTEGYDFYDAEAFTKAIDVPGASKPEKDSHRNTAQFGPQTPSSARDIDCNNLGRTASSDSYGQDHAQILSLSSPNNHGDKELDHHNEYSGRIRGHRDIESPERVRGKGIWDIHGPMLNSESLEDVFAISQATKGTRTSASMSQELSGSMPSDAGTIEMTLSTRQPVASTSPQVSFQNRQPEPTPLEKAEHSDSPTIGEYDYFKWNRDPPFPFPKPSGVSDSMSTCAPIDPYAIIQQTLEFESRKSAVNAAAIVLLLQPLVPERVISRFQAEAILKQHHSRLMNMKCFIEASQLRNLCTKNWAEGMPCWGESFPSIFGAAQRDVQVNFTCPFCNKPREIDPQAGPTAIWTCERCHRTMDPCAVCQHRHVVADLLIEIKKSTAQDQDVQEPVLTSWWYCRGCGHGGHSNCLQAWHYPVSEQGEVGEFSGGYCPQDECGHECLPDAAPPTVTSNPLSINASTSATPLGSFQRAEEPPRATAVAMATDGTASARPLVYDKAHSGNRSTLYVGPDNKVKGNTYETPQSQVSDSRDISSHYHNGAPAAPPTAPSQNAGGDVTRRKSVKFASGQGKTGSKDQQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGG3</accession>
    <name>A0ABR3ZGG3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ER membrane protein complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">oca3</name>
        <name evidence="6" type="ORF">Cpir12675_001428</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the ER membrane protein complex (EMC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Endoplasmic reticulum membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
            <orientation evidence="4">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the EMC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000022">
        <property type="protein sequence ID" value="KAL1899392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039856">
        <property type="entry name" value="EMC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055217">
        <property type="entry name" value="TPR_EMC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12760">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22890">
        <property type="entry name" value="TPR_EMC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="EMC2 TPR-like" evidence="5">
        <location>
            <begin position="114"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="162"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF22890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="328" mass="36407" checksum="927FDE7B853DB37D" modified="2025-10-08" version="1">MSPLIWPQALLSLEETLQLAQQAPKFLASNPQTYSSSPLSALLGATESRETWITYENLLLACLQTGDDESAVQILERLVRRFGDDNERIMALEGLFKEAVAKTPAQLESILNDYVAILESTQGVSLNIPIAKRRIALARSMGRVSDAISYINELLKITPTDAEAWAELADMYLSQGLYGQAIYSFEEVLVLAPNAWNVYARLGEVLFMAATAKGSDETQAPRYLAESVKRFCRSIELCDDYLRGYYGLKTVTDYLIKTPIVTKPIKNEEPMDLPEHKTLGLLNEKATAKLAEIVRHYAAGEKTWAGYKSTEISAAKALLDASSETRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGR4</accession>
    <name>A0ABR3ZGR4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PHAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000023">
        <property type="protein sequence ID" value="KAL1899354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005373">
        <property type="entry name" value="PHAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039156">
        <property type="entry name" value="PHAF1/BROMI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13465:SF2">
        <property type="entry name" value="PHAGOSOME ASSEMBLY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13465">
        <property type="entry name" value="UPF0183 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03676">
        <property type="entry name" value="PHAF1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="276"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="278"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="289"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="518" mass="57080" checksum="2902A98C65A224E3" modified="2025-10-08" version="1">MPLFSAQLFPHRALGFLTLGASLHDTITRLKAEPQCFPKLDLIYFRENPVLEPVTVNLPANGIRLRFDGSEQRLRLIEVLDFTKNHITYNNVDLAKPPATQNGSSSPAAGEPFGGPLFRHIYNKFLGPTYAGEFIPGQENDENGTYVLSYPGVAFTFPLPQSAYSPNKDVVSLLSFAPSQTAQSMAIFNGTSWAASRETIWTEILPSIKASTHLPRSKEVVPDEVSLVRIHGGGKLQLFKKWTNISSWISLGETSPQDLIAELGPPNAIYRKNDQRMTIHKQRTASHSRTREGSEDDGHSGRKLDVNSAPLITDSDDTYNESSANDAAAGTIPGECFYNYFHLGFDVLVSSPETPSPPPPLTDKTLPVVDKPHKSTAPDRLVATKIVLHGNIPGSYEFNRHRRCRWEIAYLDSAPDGYPNSETPFTTTKAQLMKRWTEALEPGEVPKWENGMVLNRGWGDSPGSSCEFLGGWEENTTVPGPLSGRDDGTSDSTTTLYGLPGLVFEVLRNDYVNAVTVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH21</accession>
    <name>A0ABR3ZH21_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 5A</fullName>
            <shortName evidence="4">eIF-5A</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ANB1</name>
        <name evidence="6" type="ORF">Cpir12675_001113</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.</text>
    </comment>
    <comment type="PTM">
        <text evidence="4">eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eIF-5A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04468">
        <property type="entry name" value="S1_eIF5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001884">
        <property type="entry name" value="IF5A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048670">
        <property type="entry name" value="IF5A-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020189">
        <property type="entry name" value="IF5A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019769">
        <property type="entry name" value="Trans_elong_IF5A_hypusine_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00037">
        <property type="entry name" value="eIF_5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11673">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR 5A FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01287">
        <property type="entry name" value="eIF-5a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21485">
        <property type="entry name" value="IF5A-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003025">
        <property type="entry name" value="eIF5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01376">
        <property type="entry name" value="eIF-5a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00302">
        <property type="entry name" value="IF5A_HYPUSINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0385">Hypusine</keyword>
    <keyword evidence="6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Translation initiation factor 5A C-terminal" evidence="5">
        <location>
            <begin position="87"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1900008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="162" mass="17853" checksum="82D01FFB68616F60" modified="2025-10-08" version="1">MSEVNDHESQFDSANAGASKTYPMQCSALRKNGYVMIKQRPCKIVDMSTSKTGKHGHAKVHLVAIDIFTGKKLEELCPSTHNMEVPTVKRSEWQLVNVDDDGYMGLIDDSGGSKDDLKVPESDVGAKIMAMWEEEKDIVVVIQQAVNEECAIDVKEAPRGSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHK5</accession>
    <name>A0ABR3ZHK5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Eukaryotic translation initiation factor 3 subunit E</fullName>
            <shortName evidence="4">eIF3e</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">INT6</name>
        <name evidence="7" type="ORF">Cpir12675_001501</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the eIF-3 subunit E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000024">
        <property type="protein sequence ID" value="KAL1899308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21378">
        <property type="entry name" value="eIF3E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03004">
        <property type="entry name" value="eIF3e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016650">
        <property type="entry name" value="eIF3e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019010">
        <property type="entry name" value="eIF3e_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10317">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09440">
        <property type="entry name" value="eIF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016255">
        <property type="entry name" value="eIF3e_su6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01186">
        <property type="entry name" value="eIF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="6">
        <location>
            <begin position="245"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR016255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="439" mass="50464" checksum="BC571C2AFE293A3B" modified="2025-10-08" version="1">MAVETAASSGHNYSLVAKFAPQLSRHLFLHLIEFESQRAQQSNDESAMRNILEAKFELMKDTNMADYVANMYCQLHGVDNAPEEYAQKRQAVLAQIETSEAETSKISDLLMQEEVVDAFRSDKVANLQFLEKNHGVTIDMVNGLYEHGIFHFRCGNYADAADLLYKFRILSTDDDMVSKATWGKLACEILVTNWEQSWEEITRIREIIDSKLFNNPRAQLDHRTMLIHWSLFPLFNDDKNREPILEMLLSPNFINTIQTTCPWILRYLVAAVITGRSRARSSSVHQKQMKDIVRYVRQELYEYQDPVIEFISALYLDFDFDAAREALRKSEEVCQNDFFLLNSTDAFVEAARHLICESYFKVSSLVSIHDLSEKLGLNPDDGEKWIVKLIYESRIDAKIDAQAGTITINQMQNNVHQQIVEKTKGVVFRTSVMSTALSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI42</accession>
    <name>A0ABR3ZI42_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pre-mRNA-splicing factor rse1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RSE1</name>
        <name evidence="6" type="ORF">Cpir12675_001225</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000018">
        <property type="protein sequence ID" value="KAL1899726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058543">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23726">
        <property type="entry name" value="Beta-prop_RSE1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="4">
        <location>
            <begin position="20"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="5">
        <location>
            <begin position="464"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="3">
        <location>
            <begin position="856"/>
            <end position="1180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1214" mass="133133" checksum="596819E64117B87C" modified="2025-10-08" version="1">MATTSNMFMYSLTIQPPTHITQAVLGQFSGTKEQQIATASGSTLTLLRPDPILGKVVTLLSHDVFGIIRGLAAFRLAGSNKDYLIVSSDSGRITILEYNSASNRFERVHLETFGKSGIRRVIPGEYLACDPKGRACLIAAVEKNKLVYVLNRDAQAKLTISSPLEAHKPAVHVLSLVALDVGYANPVFASLETDYSEADQDPTGHALDEYETQLVYYELDLGLNHVVRKWSDAVDPTASLLFQVPGGNDGPSGVLVCGQENITYRHSNQEAFRVPIPRRKGATEDPSRKRSIAAGVMHKLKGNVGAFFFLLQTDDGDLFKVTLDMVEDAEGNATGEVKRIKIKYFDTIPLSTSLCILKSGYLFAATQSGNHQFYQFEKLGDDDNELEFSSDSFPTDPKASYEAVYFNVRPLENMALVESIDSMNPLMDCNVANLTGEDAPQIYAACGTGARSTFRSIKYGLAVSEIVASELPGVPSAVWTLKLNRSDKYDAYIVLSFANGTLVLSIGETVEEVSDSGFLTSVPTLAAQLLGENGLIQVHPKGIRHIINGEVNEWAAPQHRSIVSAATNDSQVAIALSSGEIVYFEMDTDGSLAEYDDKKEMPGTVTCLSLGDVPEGRRRSSFLAVGCDDCTVRILSLDPESTLESKSVQALTAAPSSLSIMAMEDSSAGGSTLYLHIGLSSGVYIRTVLDEVTGQLTDTRLKFLGPRPVKLFKIFISKRTCVLALSSRPWIGYADPLSKSFMVTPLSYVDLEWCWNFTSEQCEEGIVGVQAQSLRIFSIDKLGDTLIQRSTMLTYTPRKLVKHPELPMFYTVESENNTLAPDLRQQLIAAGTEAGVESEVLPPADFGYPKGRGRWASCISVIDPLGDEFEPQVLQTVDFSNNEAATSATIAPFTSQDNENFLIVGSGKDIKLNPRTSTEGNIHVYRFLNDGRELEFIHTTKVEEPPTAMIPFQGRLLVGIGKVLRIYDLGMKQMLRKCQVDLGGHLITTLNSQGSRITVGDVMQGMTFVVYKTSSNKLIPFADDSINRWSTCSALVDYESVAGGDKFGNFWIVRAPVKDSEEADEDPSGTHLLHTRGYLHGTPARLSCMVHFYTQDPPTSITKTSLVVGGQDVILWSGLMGTIGVFIPFVSREDVDFFQALETHMRNEDPPLAGRDHLIYRGYYVPAKGVIDGDLCERFALLSNDKKQMIAGELDRSVREIERKLSDIRTRSAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI43</accession>
    <name>A0ABR3ZI43_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GTPase regulator Nrf1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nrf1</name>
        <name evidence="7" type="ORF">Cpir12675_001080</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000015">
        <property type="protein sequence ID" value="KAL1900080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051572">
        <property type="entry name" value="VTC_Complex_Subunit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140:SF1">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE COMPLEX SUBUNIT 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="DUF202" evidence="6">
        <location>
            <begin position="24"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1900080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="133" mass="14951" checksum="2BAFD5B19DA0D99C" modified="2025-10-08" version="1">MSTQPLLQTAPGKRIALPTRVEPKVFFANERTFLSWLNFTVVIGALAIGMLNFGDRPAFISSFMFTGVAMLTMIYALTTYHWRAKSIRMRGQAGFDDRFGPTFLAIILMLAIVINFVLRISYDNSSKHVDPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI68</accession>
    <name>A0ABR3ZI68_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein YIP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_001112</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Golgi apparatus membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the YIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006977">
        <property type="entry name" value="Yip1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039765">
        <property type="entry name" value="Yip5/YIPF1/YIPF2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12822">
        <property type="entry name" value="PROTEIN YIPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12822:SF2">
        <property type="entry name" value="PROTEIN YIPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04893">
        <property type="entry name" value="Yip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Yip1" evidence="8">
        <location>
            <begin position="91"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="282" mass="30947" checksum="BF23A348A6B0FC84" modified="2025-10-08" version="1">MSGSGYDAVVDVDDDGDLGRTDLQDDLEFHNSTFNESSGRRKGSSGGGLLPPPATAPSSTGQKHMLWSVGFYAQFFDVDTSAVLDRCFAALYPRANFLDVLEGNPDLYGPFWIATTVVLILFLGGTISEYRALNHGDEFVYNFKLLSGAAGLIYGYTLFVPVALFGALRYFGCESANLLECWALYGYGNLIWIPVALISWSPIDILNWAFVGVGCAMSIMFLVRNLYPMLTATDRKTSQIMLIVIVVLHMALSLTIKFLFFAHKSPLHDSSKDGDKLALFAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ90</accession>
    <name>A0ABR3ZJ90_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000753</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42678">
        <property type="entry name" value="AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42678:SF37">
        <property type="entry name" value="AMIDASE C869.01-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045752733" description="Amidase domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="82"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="582" mass="64159" checksum="5249EBA604F574A1" modified="2025-10-08" version="1">MFPLSKLAAAILQFGVFAAANIGGDWGLTDSEILFPLEKNINTPELFTMPHCGGFILEEATIDQMQEGMSNGTLTSMSLTICYLTRVQQTQNYINSVMQVNPDVFKIATQMDLERSQGKVRGPLHGIPFLIKENIATKDSMETTAGSNALLGSIVPRDAFTVQKLRDAGAVLFGKSTLSEWADMRSSYYSEGYSARGGQARNPYNLTNNPGGSSTGSATAVSANVIPFSLGTETDGSIINPALRNGIVGFKPTVGRTSRAGVVPESEHQDSVGTFGRTVRDAVYAFDAIWGIDSRDNYTDGQKGFMPKDGYVPFLSDKTALNGSTFGLPWDSFWKYAPNEQIDVLLKLVKLIEAAGATVINGTEILNGDEFISKDSWDWDYGTTRGFPNKSEFTVIKVDFYNNIKSYLSELTNTRMRSLEDIIKYNNENSGTEGGQPRSHPAFPSGQDYFLASAATKGEQNEEYWEALHYIQTTTRKGIDYALNWEGKKLNGLLVPSSVGQSFQIAAQAGYPMVTLPVGIKDISYIPYGVGIMQTAWKEDELVKYASAIEDLQLTRPGWEYKRTRPEWRGYMTRNLPVPFLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJA3</accession>
    <name>A0ABR3ZJA3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein kinase C</fullName>
            <ecNumber evidence="2">2.7.11.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="primary">PKC1_1</name>
        <name evidence="23" type="ORF">Cpir12675_000769</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.13" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004697">
        <property type="term" value="F:diacylglycerol-dependent serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd20822">
        <property type="entry name" value="C1_ScPKC1-like_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20823">
        <property type="entry name" value="C1_ScPKC1-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11620">
        <property type="entry name" value="HR1_PKC-like_2_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05570">
        <property type="entry name" value="STKc_PKC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.160">
        <property type="entry name" value="HR1 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011072">
        <property type="entry name" value="HR1_rho-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036274">
        <property type="entry name" value="HR1_rpt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037312">
        <property type="entry name" value="PKC-like_HR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00130">
        <property type="entry name" value="C1_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02185">
        <property type="entry name" value="HR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00109">
        <property type="entry name" value="C1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00742">
        <property type="entry name" value="Hr1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46585">
        <property type="entry name" value="HR1 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51860">
        <property type="entry name" value="REM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00479">
        <property type="entry name" value="ZF_DAG_PE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14 16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9 23" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5 23" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="REM-1" evidence="22">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="REM-1" evidence="22">
        <location>
            <begin position="132"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="18">
        <location>
            <begin position="215"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="20">
        <location>
            <begin position="446"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="20">
        <location>
            <begin position="514"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="19">
        <location>
            <begin position="823"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="21">
        <location>
            <begin position="1083"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="69"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="343"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="582"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="710"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="7"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="346"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="17">
        <location>
            <begin position="372"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="382"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="597"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="624"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="664"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="718"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="744"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="852"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAL1900756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1148" mass="129737" checksum="7FFCA0FF4167A87D" modified="2025-10-08" version="1">MNDEDKIQSIQAKIQRENALINAANAMRAQTTNEAVRSRLDSQIRDARRNVQFFQDKLMELEARRGVENMSLSSPSRPLSSDHNLPSPPPKDSSWPPGDRSATAGQDYSTSPSSNQAQPKARQNFSKLDIIKYDNPYLGPRIQMMLGQLQFKLYVEEQYLKGVEKMVQLYSMDGDRKSRADAAARRVESKQKMILLKQAFKRYEELNIDSEAADAHDDESINATNMRKPLSGQLSIKVMAVRDVTHTTTARFSRGPETFVAVKIEDSVVVRTRSSRNDRWEAEHHVVDIDNANEVELTVYDKSGEYPMPIAMLWVRLSDIVEEMRRKRNEAELYNAGWVSADRMGQHNNQPPSQFPMDSQGQFNTSSSMGSLVGGPHGGPGQNTSGQPQPQIANQPITDWFILEPSGEIQLELSFVKQNRRPADFAGLGRRAAVRQRKEEVHEMHGHKFVQQNFYSVMRCALCGDYVKYSTGMQCEDCKYFCHTKCYTNVVTKCISKSNAETDPDEEKINHRIPHRFQPFSNMTGAWCCHCGYILPFGSKKNSRRCAECGLYCHAQCQHLVPDFCGMSMAVANQILDSIRTQKKKTSVIGEKTHRPSQSTDLRSSSSSAYGLASPQSPQLQKRPVSNTVPSSSSAASLTSIGQQQQRPQQGYAGYPGGADPEYSAQTPDDTYSQYGGSHQHQHQHQQHQHQQLPVQQPTQAKYNPADYANIDAYGNRPAPQQQHHQQQQQQQHHPMHAPSQQHLPQISQQVPLIQPHQQPSPDMSSGYGNQPLQQQMVKPEHQHGAISPSAVAGASGIPVHQRKPLPSATDPGTGQRIGLDHFNFLAVLGKGNFGKVMLAETKRSKRLYAIKVLKKEFIIENDEVESIRSEKRVFLIANRERHPFLTNLHACFQTETRVYFVMEYVSGGDLMLHIQRTQFGTKRAQFYAAEVCLALKYFHENGVIYRDLKLDNILLSLDGHVKIADYGLCKEDMWYGSTTSTFCGTPEFMAPEILLDKKYGRAVDWWAFGVLIYQMLLQQSPFRGEDEDEIYDAILSDEPLYPVQMPRDSVSILQKLLTREPDQRLGSGPTDAQEIMSQPFFRSINWDDIYHKRVPPPFIPQIKSATDTSNFDSEFTSVTPVLTPVQSVLSQAMQEEFRGFSYTADFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJE0</accession>
    <name>A0ABR3ZJE0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000709</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47842:SF1">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47842">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="1">
        <location>
            <begin position="186"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="699" mass="75279" checksum="FF3C28D9E914EF86" modified="2025-10-08" version="1">MVQNAVSDDGFVIPLIDFSSFLHGSEADRKEIAKAILVGFQTAGFIYLKNIPISAESRATAFSMSSHFFTLPEEDKLALSWTTPAANRGYSAFGREKTSLLTDKTEIDALRNATPDIKESLEIGREGEEGHPNLWPDEQRTGLEGFRAMMTSFFSECKQLHIEIMRAIGIGMGLGDKYFDPYVDKGDNTLRLLHYPPVKADAFKTAVRSGHHSDYGSITILFQDDRGGLQICSPNGKFVDATPIKDTVVINAGDFLARWSNDTIKSTVHRVVEPPVKSAEYPARYSIAPNFDRDIEALPGTYATESEKKYGILNSGHTFGEDYRFTKVLRDIVAAELPDVNIETLVYPRYETRGNLGECVGRFRDWLQEKVIDLEVDAGTQSPTIDPSVHTILVGHSMGGIVAAETVIALTSDIPILPTSSPDSNAASTSDATGCTTGATDASVPFSSGIMFPYVQGVLAFDTPFLGLSPGIIAHGAEEKYMTASSVAGQLSDFWSRNASAASSASNVASGQSAAAAATSSSRWGTWGKLAIAAGGAAVVAAGAGAAWYNRDNISSGIVWVGSHLEFVGVLGKPEELRKRVAYMVRLQKEQGTGFVNMYTLLGNGAAKANYASLLYSKDRTFCVLPTGNAPSGAWRAVRNNKAGDEITAHINMFESSKNSGYDDLVVAASDYIAAMVKTTDWYKSAGQKAIKDTSEPLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJF8</accession>
    <name>A0ABR3ZJF8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cysteine protease</fullName>
            <ecNumber evidence="11">3.4.22.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ATG4</name>
        <name evidence="13" type="ORF">Cpir12675_001352</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[protein]-C-terminal L-amino acid-glycyl-phosphatidylethanolamide + H2O = [protein]-C-terminal L-amino acid-glycine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine</text>
            <dbReference type="Rhea" id="RHEA:67548"/>
            <dbReference type="Rhea" id="RHEA-COMP:17323"/>
            <dbReference type="Rhea" id="RHEA-COMP:17324"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:172940"/>
            <dbReference type="ChEBI" id="CHEBI:172941"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:67549"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Preautophagosomal structure</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the peptidase C54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.22.-" evidence="11"/>
    <dbReference type="EMBL" id="JAWDJO010000020">
        <property type="protein sequence ID" value="KAL1899674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005078">
        <property type="entry name" value="Peptidase_C54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046792">
        <property type="entry name" value="Peptidase_C54_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22624:SF49">
        <property type="entry name" value="CYSTEINE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22624">
        <property type="entry name" value="CYSTEINE PROTEASE ATG4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03416">
        <property type="entry name" value="Peptidase_C54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0072">Autophagy</keyword>
    <keyword evidence="4 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 11 13" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Peptidase C54 catalytic" evidence="12">
        <location>
            <begin position="121"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1899674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="454" mass="50477" checksum="0C1AD8DFBECBE3B1" modified="2025-10-08" version="1">MSIVDISKRIIQSLWDPEPTNDRLQNVPVWCLGCSYDLSSAKAPPIKPPPHTAAKYTATIVLDTSSAGGSASPENVLEEDNLDNIEAAEDIENASDDLVETATSDLPVAKTESPDGGWPVEFLDDFESRLWMTYRSNFQTILKSSDPGAIGALSLSVRIKSQFSDQNGFTSDSGWGCMIRTGQSLLANTMAIHALGRGWRLGHYDHAERSIISKFADDPEAPYSIHNFVKHGAEACGKYPGEWFGPSATARCIQSLVNERELDLRVYSTGDSADVYEDRFMQVAKPDGIKFIPTLVLVTTRLGIDKITTVYWEALVATLQMQQSVGIAGGRPSSSYYFIGVQGMFLYYLDPHVTQPALQFHKDVSEYEHGELSTCHTRRLRKLHLKEMDPSMLIGFFIRSEDEWREWRAGVKHVQGRPVISVFDRNPLGDVNERAEAIDEVESMSEADGLEDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKT5</accession>
    <name>A0ABR3ZKT5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_000509</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047011819" evidence="3">
        <location>
            <begin position="17"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="238" mass="23064" checksum="B01B34F712A8F129" modified="2025-10-08" version="1">MQFSTVAIIAAAGAMASLPYGSAPVGTGKPAQVTSTVFRTEFHTITDCAEYVTDCPSHATKVVTNIVAVSTTICEAEENKPSAPPAGPAGPTAPGGPYVPVAHSAPPYPTGTAPAGKPEKPTKGTGLPKLPAGPAGTGVVGNAAVPGSTLPAAPVDEECVTARVKLITTMVPSVITVTEEVPCETAPPSKPMAPSGGAPSGTGVVTPPSGVPVTAGAMSLAGSAVMAVAGAVAAFAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL93</accession>
    <name>A0ABR3ZL93_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial succinate-fumarate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SFC1</name>
        <name evidence="12" type="ORF">Cpir12675_000683</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049563">
        <property type="entry name" value="TXTP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45788">
        <property type="entry name" value="SUCCINATE/FUMARATE MITOCHONDRIAL TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45788:SF2">
        <property type="entry name" value="SUCCINATE_FUMARATE MITOCHONDRIAL TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="8"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="109"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="213"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1900810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="317" mass="34446" checksum="879EB510111D48EF" modified="2025-10-08" version="1">MTQHRKKPSVATNMIAGGGAGMTEALVCHPLDTIKVRMQLSRRGRQPGKPARGFIRTGTEIVKKETPLALYKGLGAVMTGIVPKMAIRFTSFEAYKSFLADPAGNVSSGSTFIAGLAAGVTEAVAVVTPMEVIKIRLQAQHHSMADPLDIPKYRNAAHALYTVVREEGASALYRGVSLTALRQGSNQAVNFTAYTAFKDSLSRWQPELEGSKLPSWQTTIIGLISGAMGPLSNAPIDTIKTRLQKTPAEPGVSAWQRIAGIAKDMFKQEGFHAFYKGITPRIMRVAPGQAVTFTVYEFLREKIEKSDPAHQAVNYEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLU6</accession>
    <name>A0ABR3ZLU6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mediator of RNA polymerase II transcription subunit 6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">Mediator complex subunit 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">MED6</name>
        <name evidence="10" type="ORF">Cpir12675_000389</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the Mediator complex subunit 6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.580">
        <property type="entry name" value="Mediator complex, subunit Med6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007018">
        <property type="entry name" value="Mediator_Med6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038566">
        <property type="entry name" value="Mediator_Med6_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13104">
        <property type="entry name" value="MED-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04934">
        <property type="entry name" value="Med6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="183"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="257"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="278"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="296"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1901698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="314" mass="33823" checksum="248F4AFD8900C3F2" modified="2025-10-08" version="1">MPAQEPKLDEIQWRSPMAVADLNGIHSNTILYYFAQSPFFNATSNNAVLFSQAMHNQNMFPLIQTREAFEGHLRTMAGLEFMVVEEPAEMGPGMGTGVWIINKQMRKKQPGEGDEVTVLATYFVVGENIYQAPMLADIINARVATISSSMRSIITQAESIRSWKPSQGHTYILPLVKKETADVASSTPGNSQVSQSQQATNVGPDASEERALQHLAEKSMKIHVRYGGDYIDENPITGEPGKFHLSSTGRSAAAAAAASSTASASVPPLASVGSLKAGKKDDKKDASGSSKERKGSQKPRRRKSKSIATTPAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMW7</accession>
    <name>A0ABR3ZMW7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="289" mass="32038" checksum="EA63C1DC2E4ACCC4" modified="2025-10-08" version="1">MSSLSLASPAPGPTLSDMQPSASSNGPYSGDPPAVPSAATPTPSLGHPLPPLLDRTDSITMPCGYHCRWARPGDEDAIATIYFGAFTGCQIRMHCFPETGPESSARHWWKSEAHHWLMHEQLYYVHVVEDASTGNVIAFCKWSYHPNGYKISEQPQHDGPSLPEINPRLAEHFFSQMGVERERIHSTTPHIILSMLSVDGKHQGKRLAGVLLSWGITQADKLGLPIYLESTTMGYPVYQKRGFQKIGSIMFDQTSQTDPADDVRNFEHWSKQNLVVMIRSPNCVKAGNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMZ3</accession>
    <name>A0ABR3ZMZ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arb2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000299</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048263">
        <property type="entry name" value="Arb2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053858">
        <property type="entry name" value="Arb2_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21357">
        <property type="entry name" value="FAM172 FAMILY PROTEIN HOMOLOG CG10038"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21357:SF4">
        <property type="entry name" value="FAM172 FAMILY PROTEIN HOMOLOG CG10038"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22749">
        <property type="entry name" value="Arb2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arb2" evidence="2">
        <location>
            <begin position="15"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="425"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="446" mass="50121" checksum="1AF543EE42AFFD45" modified="2025-10-08" version="1">MFRRTWEGLPQDTIFGDTLAELGYFINDIDEVRSLDNPNNYFRFHLSKNDRINERQRFHFNDALESIIIDRLHGEGLETARLPLEVKSPSQPHIPILVSKYLAQRRRVILFLGESTQSLGVLSHRIIGGRGGINEGSLVSLVKSLAKQQSTPNDSNPPGIIIANLGGNWWWPEGKRALNPAMAQAIPLGSSAFNGQEYDGELNAVPQLETWKRHLRYLMNTAVPSLIAHDTLIDVIAVGDAVDGFLEYLNDETAWALNKDRLNAGAFMGGVFSTDPINVGLSNFLAQRCRTWAVHQAPVNAPLLGLTGHRSPSTTNSIVCPVYSSGEPYYNECSLVRAKDCVTQWLYEVSQMSDYKNPHLDELTIFGDNTATAENDDDWTIDHNSEPRHIEPSYPEPDLAEDDFQVIRNLVGDYHNWNKERLQETDQIIESSGQEKEKDGKQGLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN79</accession>
    <name>A0ABR3ZN79_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Carnitine O-acetyltransferase yat1</fullName>
            <ecNumber evidence="9">2.3.1.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">YAT1</name>
        <name evidence="9" type="ORF">Cpir12675_000055</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carnitine/choline acetyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.7" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004092">
        <property type="term" value="F:carnitine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.20">
        <property type="entry name" value="Choline/Carnitine o-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.70">
        <property type="entry name" value="Choline/Carnitine o-acyltransferase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000542">
        <property type="entry name" value="Carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042572">
        <property type="entry name" value="Carn_acyl_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039551">
        <property type="entry name" value="Cho/carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042231">
        <property type="entry name" value="Cho/carn_acyl_trans_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589">
        <property type="entry name" value="CARNITINE O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589:SF29">
        <property type="entry name" value="MITOCHONDRIAL CARNITINE O-ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00755">
        <property type="entry name" value="Carn_acyltransf"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00439">
        <property type="entry name" value="ACYLTRANSF_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00440">
        <property type="entry name" value="ACYLTRANSF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Choline/carnitine acyltransferase" evidence="8">
        <location>
            <begin position="88"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="domain" description="Choline/carnitine acyltransferase" evidence="8">
        <location>
            <begin position="724"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="610"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="662"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="690"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="901"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="616"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="904"/>
            <end position="923"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="938" mass="104427" checksum="5CC83BD2E53E20D0" modified="2025-10-08" version="1">MSSQTTNKPAHAKVRFTEPCPFGETLNKASTSVYIPRSVPDSSDLIKTLDPKKSATVPLPRSPMATSNLPRGGQPGLTFAAQDKLPKLPIPSLEETLKHYLGAVKPLQEPSEHEETKLVAERFLAEDGPELQKKLIEYADGQSSYIEQFWYDSYLNFESSVVFNLNPFFLLEDDPTPARNNQVTRAASLVYSSLEFVRAIRLEELPPDTVKGKPLCMHQYSRLFGTARVPTENGCKIEAYPESQHIVVMCHGQFYWFDVLDNNNDPIMTEKDLSVNLQTIIDDATQLPILETAKGALGLLTAQDRKQWARCRQVLSQEQGRNNADCLSMVDSALFILCLDYNEPSGVAGLCQNMLCGSSQLEKGVQIGTCINRWYDKLQIIVCKNGSAGINFEHTGVDGHTVLRFASDIYTDTILRFARSINGQAPSLWATTSPDPAKRDPESFGDVTTTPHKLEWDIPDSLSLAVRFSEAHLTDLVMQHEFECLDFGAYGKNFITSMGFSPDAFVQMAFQSAYYSLYGHIDCTYEPAMTKTYLHGRTEAIRTVSQESVDFVQAFWGTATSAEEKVDTLRKACQRHTTTTRECAMGKGCDRHLFALLSIWRKTVDDELNSSRADYSEPSEYSSPLSYSGESMDSSALDDSILVQRFEEHAISDDVEIGATDLSRGDIAPNGRHSDSNASPLDTTEYLISADGTDNTTVSPPSMVIRSRENSTSSRASRSRDTQPLPSLFADSGWDRLNTCILSTSNCGNPSLRQFGFGPTSGSGFGIGYIIKDESISICVSSKHRQTSRFLGNLESYLLEIRRMLRITTQQSNIKASRAREIDRQTRKNVPRLQTHAHANGHKMPPAKARLIHGRQLDVLRLRGQSPSGTRSPTEYSIATSEDCQGGYGFFDAGNFLHPLRPLMEGRDSSRDTRPSERAQEQARRRRDVGKILPLAEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNC0</accession>
    <name>A0ABR3ZNC0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chitin synthase export chaperone</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022057">
        <property type="entry name" value="Chs7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35329">
        <property type="entry name" value="CHITIN SYNTHASE EXPORT CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35329:SF1">
        <property type="entry name" value="CHITIN SYNTHASE EXPORT CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12271">
        <property type="entry name" value="Chs7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="290" mass="31871" checksum="0696C15AAF6A6C14" modified="2025-10-08" version="1">MTRFGDFDVFCQDSTLAVCNLMSKHHNQSGTWGGCELKGIPLSGGRHLGNLGVILLSAIAIVMTAFLILLSSRRKAAVGRIEMEVFLGGYAFIQFCEIFTIGSFPLNEKVRVFFTALHIGAIIATTWVLMLNAVVGYQILDDGTPVSVGLVFGSAAPLFLGTVYIAFDTGYSWTGYWDDSYSGSNRHIALYVLYQVAPLIFLAVYFVLETVLVVKVLEEWVPLIWLGGAVAFFALGQVFNYTISSSICNGTSGKIDGSMFETFFTMISVSLVWYFWTTITEDDWASSAYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNC1</accession>
    <name>A0ABR3ZNC1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">SP-RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Cpir12675_000339</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NSE2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16651">
        <property type="entry name" value="SPL-RING_NSE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026846">
        <property type="entry name" value="Nse2(Mms21)"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004181">
        <property type="entry name" value="Znf_MIZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21330">
        <property type="entry name" value="E3 SUMO-PROTEIN LIGASE NSE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21330:SF1">
        <property type="entry name" value="E3 SUMO-PROTEIN LIGASE NSE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11789">
        <property type="entry name" value="zf-Nse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51044">
        <property type="entry name" value="ZF_SP_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SP-RING-type" evidence="12">
        <location>
            <begin position="329"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="411"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="23"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="213"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="420"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1901649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="454" mass="51085" checksum="6D34272A0A0EBADF" modified="2025-10-08" version="1">MLSEGRRRRLMNNSNTSPRRSSGARDQESDGDDMEPHRSTSRGVRYEEMAGPPNASSAEAMKKLVASRESQRIIEESRAAMDGINKAIAAVNDAMLSQRKNVVKIQRQAGGGNSGVDGEEKGLWGENEIEERDEYLANTQQKAESALQKLVDSSIDITTRAEVAFRQLIDVIAETEDFNLAIESAAEQVRVASRQRAILEDEQARARAIREQENEDGLEAEEASEDQKPAVNDGALEATEIAPFAPLKDTLLAAVRAKDGAYNSMPLYQRYATNNDYAAFRRQLHRSIYDDTREVPDKKRWFDEDGRPVLPTREALLGIELDTEMRNGSDDELVIQRVKQDSKCPLSLRELENPYGTSKCIHVFEKEAIFAYVAQSGRNATVQCPQSGCSATFTRSDLILNQEVLIQLERRKRRRARDESDNEEEQEDADEYEYASINTTAIDISMDVTKREPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNC5</accession>
    <name>A0ABR3ZNC5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000383</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="186" mass="19510" checksum="A4C0A2BD0AD4AA29" modified="2025-10-08" version="1">MASMPSELISASTVQAQLEGARCSPEGLWNCMTTSFQRCTNGAWSEPVAMAPGTECYPTGVAVDFQIGFSNGHGSGVDNCASMVETETTTTITATEPADIDMPSLTPYFLPSSWAYSSEPSPSVPSPSSSSSSSSSWTSTPATTLERESTTPTANVQADWGERNYEASLDVKVLVGIVAGMLVGWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZND5</accession>
    <name>A0ABR3ZND5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA sliding clamp PCNA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">POL30</name>
        <name evidence="7" type="ORF">Cpir12675_000354</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processivity during elongation of the leading strand.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the PCNA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00577">
        <property type="entry name" value="PCNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.150.10">
        <property type="entry name" value="DNA Polymerase III, subunit A, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00317">
        <property type="entry name" value="DNApol_clamp_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046938">
        <property type="entry name" value="DNA_clamp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000730">
        <property type="entry name" value="Pr_cel_nuc_antig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022649">
        <property type="entry name" value="Pr_cel_nuc_antig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022659">
        <property type="entry name" value="Pr_cel_nuc_antig_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022648">
        <property type="entry name" value="Pr_cel_nuc_antig_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00590">
        <property type="entry name" value="pcna"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11352">
        <property type="entry name" value="PROLIFERATING CELL NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11352:SF0">
        <property type="entry name" value="PROLIFERATING CELL NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02747">
        <property type="entry name" value="PCNA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00705">
        <property type="entry name" value="PCNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00339">
        <property type="entry name" value="PCNACYCLIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55979">
        <property type="entry name" value="DNA clamp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01251">
        <property type="entry name" value="PCNA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00293">
        <property type="entry name" value="PCNA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proliferating cell nuclear antigen PCNA N-terminal" evidence="5">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Proliferating cell nuclear antigen PCNA C-terminal" evidence="6">
        <location>
            <begin position="127"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="259" mass="28249" checksum="BE07DD24A430C1FD" modified="2025-10-08" version="1">MLEARLEQANVLKKIIDAIKDLVQDCNFDCNDSGIALQAMDNSHVALVSMMLKAEGFSTYRCDRNIALGINLTSLTKVLRAAQNEDILTLKAEDAPDSLNLTFESGSNDRIGEYDLKLMDIDQEHLGIPDTEYAATVSMPGAEFRRICTDLIAMSESVTIEASKDGIKFSSLGDIGNGSVTLRNTTNADKPELDVGIQLSEPVSLTFSLKYLVGFCKASALSNTVKICLSNEVPLLVEYNISGSSYLRFYLAPKIGDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNX0</accession>
    <name>A0ABR3ZNX0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Probable beta-glucosidase btgE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Beta-D-glucoside glucohydrolase btgE</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Cellobiase btgE</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Gentiobiase btgE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Cpir12675_000279</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050732">
        <property type="entry name" value="Beta-glucan_modifiers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631:SF24">
        <property type="entry name" value="FAMILY 17 GLUCOSIDASE SCW11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0134">Cell wall</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="77"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="81"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00042762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1901770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="481" mass="50002" checksum="DA264333233F98EA" modified="2025-10-08" version="1">MRAVVIATAFAGIASAGHAHRRAHEAVRAERRGGDYGLYPTGAAAADEECVCKTVYGTMYGEPMIYIPDQTTVESSSTAIPTYTEGPSTTTSSSVSVAPTPAAPVVPTTSTTSLYTPAVPHISNAVPSAPAPAPQTPKVTEAKVPSNVPVAPAPHTPKVTEANVPGNVPVAPAPQTPKVTEAKVTKTAVASVVPSKPATPKPSSPSSSVPGALFPGQKTDHWAITYTPYTDDTGSCKTKDAVDADIKDIKSMGFTTIRVYSTDCDTLPNVGAACEKYGIRMIIGIFIKEAGCAYTGEVQEQVEGIISWGKFDIVDMLVIGNEAVFSGLCSAAQLTTLITTVKGTCSGAGYTGPYSTAETVNVWEANGSLLCDVIDVAGAQTHPYFNAETTPSKAGSFVKGQIDIVKGICGKPAISLECGWPTKGTCNGAACPGVSEQTQAMASVRETCGEEVVFFTYGEAHWKNPGSCNCEPWFNIKAIFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP44</accession>
    <name>A0ABR3ZP44_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Ubiquitin carboxyl-terminal hydrolase 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ubp10</name>
        <name evidence="13" type="ORF">Cpir12675_000473</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02669">
        <property type="entry name" value="Peptidase_C19M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033809">
        <property type="entry name" value="USP39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF16">
        <property type="entry name" value="U4_U6.U5 TRI-SNRNP-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBP-type" evidence="12">
        <location>
            <begin position="75"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="11">
        <location>
            <begin position="198"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1901603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="532" mass="60774" checksum="1E72EC02980EF313" modified="2025-10-08" version="1">MPGKRNADEALLEDLSGFMSPASKRSRLDSHEFQPEESVAPPTPSAVTDNSNDEANDDEPMDTAPLRQSAPTTGYDDLYLDTINRNVLDFDFEKLCSVTLSNINVYACLVCGKYFQGRGPKSHAYFHALDEDHHVFINMRTQKVYVLPEGYEVTSKSLDDIKFVSSPHYQRSEVAMLDRKPAKSWTYGGDKEYTPGFVGMNNIKQNDYVNVVVQALSHVPPLRNFFLIEGVCRRSELVQRYSLLVRKIWNPRAFKAHVSPHELLQEIALRSNKRFTQTTQADPVEFMSWFLNNLHLGLGGSKTKPGSSVVQQAFQGRVKVESQAISARADASDRLRFEEAAEVKMDIVRFLLLTLDLPPAPLFQDELEKNIIPQVPLTTILKKYNGVTAQEQLAHRKRYRLLHPLPPYLIFHIKRFSQNKFVSERNPTIVTFEERGLDVSPFVEPDATHPPSKPIYYDLVANIVHEAVRAKDDVADSGEEMKTWKVQVKDRGRGEWTVCQDLFVDKVQSELLFSGESYLQIWERRREPAKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPJ3</accession>
    <name>A0ABR3ZPJ3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_000067</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058841">
        <property type="entry name" value="HTH_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040554">
        <property type="entry name" value="KPWE_PEX14_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25871">
        <property type="entry name" value="HTH_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17733">
        <property type="entry name" value="KPWE_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PEX14-like helix-turn-helix" evidence="3">
        <location>
            <begin position="16"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Peroxisomal membrane protein PEX14-like KPWE" evidence="2">
        <location>
            <begin position="156"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="235" mass="25174" checksum="7A86253BAC1A3D01" modified="2025-10-08" version="1">MNKTPEAITDKPTTGDDVFIAFDSYPWNQDPRFATLVKSMASRGIPMTTGPAMLVARTAFATKFLGLAIDKEAYTVWARGKGPEHDIVDQHLAQGFAIVGDDSDNQHQKTGTGTTATATAAIDTLDWQAAAPKLAAVVDRRSESAGDPNGMGNGQPPAKFAELLRFMQEGTPIPGVRTIPSTVERSANIKPFGARTVPRKPWEHDDPQKGLVGSDATNGSIDIEFPSLETENPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFL3</accession>
    <name>A0ABR3YFL3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">2-dehydropantoate 2-reductase (Ketopantoate reductase) (KPA reductase) (KPR)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PAN5_2</name>
        <name evidence="6" type="ORF">Cpir12675_006707</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ketopantoate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000357">
        <property type="protein sequence ID" value="KAL1887076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050838">
        <property type="entry name" value="Ketopantoate_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43765:SF2">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43765">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketopantoate reductase N-terminal" evidence="4">
        <location>
            <begin position="48"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Ketopantoate reductase C-terminal" evidence="5">
        <location>
            <begin position="257"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="419" mass="46369" checksum="234A57DA7054F6C7" modified="2025-10-08" version="1">MPALRWLTLSEAYAIPPRVYAWSARNFPHLAQSFTSEHTGLSQPHKRVYIVGVGNLGRLFAMSLAKSPTKPPITLVVRRKELLEEWIRRPGIEILRGNTVVNSRNFTVEWWSEEKPKEGPVVEVANGRTLRNIIVSTKTASALREVDRMRRYLSAESTLAFAQNGMSPLWPPSGDAYMTSRFGTKAQGPNCLAMVTKHGVTSLGLFRSKHASEADVVVGPVWLNETTGGRSQYLTDLLLAAPKLEAREQARDDLWIYQLEKLVVNSVINPTTAILRVKNGEVFADPLGPVGRAVDRLIREASQIILALIQSEVGHGILGMAEATDPALLERFSFGNLRSMIYHLCGVVVKDNVSSMLQDIKAGKETEIHDLNGWLLGTAEFLGLRDSVPTHKAIIKLVEEAATVTPEDIEDRLASKHQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFU1</accession>
    <name>A0ABR3YFU1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_006655</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000343">
        <property type="protein sequence ID" value="KAL1887185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF4">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="98"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="51"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="252"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="883"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="946"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="260"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="995" mass="112405" checksum="AB3E0109712B079C" modified="2025-10-08" version="1">MSGIPIKRSAQELFSSSSTWLNTISAADTATNDPRSADTTLKSVVLDPASVPASFPAQKPAPSEQPRESQSKRAKTNINAFSTVVKTKLQSSTRTGQACDRCKVRKIRCDALPDGCSHCVYQKISCFVTDRITGRTERRGYLKELETQIDTLQARLQDVETLLLAHGTQVFPHPLLDRETELGDVEPSAPCESFAVQEQQPPQHPSPEDGWYQYRSLWLRKVAKASCENDNPGQTAVESPHQTWATENNMMSFPRHAHRGPSSATPPSRSTRQSSTPSLIHSLSYFPSTLKADNVGYIGASMDAAPLSSLSGTKLLIMGTIIDTGDFKQPDYEEGAFNSGVLTPRYNKSVQALMQSMMNMNPILSGMDLPPREEAFRYTQWYFLMLEKFLPMLHQPTIWKMLTRIYDEPGYKPTASELVLVHMIYSTMLFHYGIRNSNSTVDKAKYNDLSNQHYHYSLSHFYRLLCERSIQACQAIALLAIHARNFPKPHATIILSNQALARAWSMNLNRRPDPAKFNKIEIEMRNRLWWVILLLNVTMQGYMGRPMPVTNRDYDVDFPEPVHDNMITEHGIDSSKNLKYPYWAGIAFFRSMPLFIDLYSHLYSAKRDPHVYAVAVAELESRLQSWKSSLPSELIVEPGPLSTFTPGSDPVSILYIQEVEVRFRFFLRHPNVAMTRDARFAADNVRICESLSEKMLIIATGLMELKSLDTTWSAMSMYGAFLFTTLAGHWQRRLTATSESMDRLRNTIDGWLAVIKKVAHLIGAGNYAVDQMRDIVNRTLEQIEADSRLTRYKQHSEDVHSDSNPHPPFFDGKMPLKTDMTFLKSFPTSQSESRPLQAFNPIQYQNQQQQALQDPSTIAVASAAQAMHNEVLNSSLYYANEADDQDDDHEEHEQHFAFPSSQVLLPPHPPPSAQDAEDDEYDWTESTGSKSVRNAWREWAEAIIENPDRASLNKPSNPYIVDPSQPPSHTGADMSSSAQWPMLAFHDPNLHNIQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGN5</accession>
    <name>A0ABR3YGN5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vacuolar protein sorting-associated protein 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">VPS11_1</name>
        <name evidence="4" type="ORF">Cpir12675_006597</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000331">
        <property type="protein sequence ID" value="KAL1887309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="entry name" value="MutL, C-terminal domain, dimerisation subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014790">
        <property type="entry name" value="MutL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073:SF47">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00853">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118116">
        <property type="entry name" value="DNA mismatch repair protein MutL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MutL C-terminal dimerisation" evidence="3">
        <location>
            <begin position="540"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="388"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="785" mass="85770" checksum="5A31189320EA7284" modified="2025-10-08" version="1">MLPAAIKTASSIRPIPSTAVAQIRSSAQLTSLNEVIVGLIQNALDAKASRIRITLDYSLGNCTVEDNGNGILPTEFDSSGGLGKAHHTSKLELQNCHGNKGVFLMSLASLSLVKITSRCKGLASQNSLTLHKAQVICRNTPSSPAERSLDSPHGTRVNVGDLFGFMPVRVRQRATADSERQWASLIWNIAALLICWPAAVSITVTHTQSVSNLAVFSTKQKKIHFRPVADRILAVRTPRLLSQANLAHNAKWEPVSASVRGVTVKGCIAHSPSPSKKAQLISIGVVPLLNSAGTDPLYEQINRVFSDSAFAQGNIDNDDVRFSSKVNSGKRPRKSFEKWPMFYFQIHLLEKEISVDRLALTPSLLTTLGDLLTAVCKEFLKKTNIITSDSKSSSSSTLRQQPLPKLSTKHSSVISHPSLPRTRSVFDSWSRMKVGQAQHPKIQANAFPKLPLVNSSGNLTRPPFEIELPAKRPKKSMTELVSQWKNPVFEIGDRGIPRLAATPSASPHNCASQGDDVSFATASMAVKSQISKDALARAHVLNQVDQKFILISVPQDKGGSLLVIVDQHAADERARLEELMTSYFPSSSPTAPAYSEVMETPLTFEVPTQEGDLLIRFQTHFCNWGVSYTCTPVSPLMQVIVSSLPPSIHARCIQDPALLITLLRAEIWSLAESYTCTSNGLGPPRASAGPHGFVARFRTCPTGILDLLNSRACRSAVMFNDPLSHDECKALLERLSRCAFPFQCAHGRPAMVPLVDFSTKHGLWEGNTEQHEYKAIVPWRKYAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGQ3</accession>
    <name>A0ABR3YGQ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Altered inheritance of mitochondria protein 32</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AIM32</name>
        <name evidence="4" type="ORF">Cpir12675_006742</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AIM32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000365">
        <property type="protein sequence ID" value="KAL1887022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03062">
        <property type="entry name" value="TRX_Fd_Sucrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009737">
        <property type="entry name" value="Aim32/Apd1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31902">
        <property type="entry name" value="ACTIN PATCHES DISTAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31902:SF7">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06999">
        <property type="entry name" value="Suc_Fer-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00040895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="332" mass="34873" checksum="AAF039E8FAD50E10" modified="2025-10-08" version="1">MTSCCPPSSDPCPTAAPDLPDSHPLTSEGLHGAIAAYLEHVVVCTGTNEWPSRIEDGVMDGSGTELGGDGGKTAMQGGRNISAEFKTLLGRNGAFQNSNFSVIASSLTGTNSGSVYLLPSFKYIPGLPDTASMGRLVTDHLLPLDASQDFGGLPSKPTACASPPSANAPLFAPTTELETNTLPFIPVSSVMVFICGHKNRDLRCGLYGPALQDAFTHELGVKGIQVLHNPPSTTESISVSADAPGPSSTTARVAMISHIGGHKYAGNVIIYIPPEMRGPDGKKHSLAGCGIWYGRVDPEHVNGIVHETIVNGRVIEQFFRGGLDTCRKIVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI72</accession>
    <name>A0ABR3YI72_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006687</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000352">
        <property type="protein sequence ID" value="KAL1887119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="103" mass="11503" checksum="E0C9BD419935CB37" modified="2025-10-08" version="1">MQNSRFHALTAKLNTSALRTSFRRHSSSSSTSSISTTASMNSATSSPVETINSVMFRQPSIVNMEAERRVFGSELGLLEPRPIVYWGGMEERMEQNSVQPFPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI92</accession>
    <name>A0ABR3YI92_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Actin-like protein arp8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ARP8</name>
        <name evidence="3" type="ORF">Cpir12675_006485</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000308">
        <property type="protein sequence ID" value="KAL1887592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10206">
        <property type="entry name" value="ASKHA_NBD_Arp8-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="79"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="568"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="80"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="615"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="787" mass="87935" checksum="AE44E5CC93122901" modified="2025-10-08" version="1">MVGKVSERVLLREGLERTDNGMKQTTWPEVVPINQKNYYTDYMKRDDQVLALRLQGDAAREQIVQSTKDRERILAQWVAKEQDGDGKTETIAKSDDDGDDDDDKSEQDNTEADYIDLENPARMIVIHPGSQNLRIGFASDPLPKTVPMVLANKAPHTESEEYDALPRRRFEEQTLEGQFGEEWSKKYRKLSEDLKMEMRANKHKVLPNSKDLVVNYNRRSDPERIPVHNDPLQVEWTETPASETACAGNEALRIPEDSQPKYKLWWPMQQGWFNENDYGTSEHLYDDFETIIEKAIRTELGLKSSMQWKKYSCIFIIPDLYDKKYVEQMLESCLTWFEFNRVCFIQESMAATFGAGYTQACVVDVGAQKTSITCVEDGMCLEDSRINLKYGGWDVTETFLRMMLFDNFPYEEINLRRRYDWLLAEELKIKHCSLAQNLVSVQLMTFHVRMPNQPTRKYQAKMYDEAYLSAMGFYHPTIFDDSAKLRGRRSLIDMSYNCYEFDLPDDPSSAAQLAILTMVKPSLKNNMVLTAQPNLLVQASSGGNGVSTPIKDRSQPFNFLAKVNEGLNSTPATSNAPSPGPGAGPDGTSTPVPPVFVFGRDTATGSPAPASVRNGTPAPSLPGAGAGAATSVAGVSASDAGASANATSAATVPQQLPRYSATELANERDLVLPIAPLDVAVLTSISHAARGDEKKLRELLGSVMVVGGGAKIPLFGSVLEDKLRAHRPDLSDKILVSSSARDMDEQVVTWKGASVFAKLSTNDSWITPFEYERLGPRILHHKVMWSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIL6</accession>
    <name>A0ABR3YIL6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="15">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Cpir12675_006288</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="15"/>
    <dbReference type="EMBL" id="JAWDJO010000277">
        <property type="protein sequence ID" value="KAL1888121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF6">
        <property type="entry name" value="ENDOGLUCANASE IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 17" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046106699" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="17">
        <location>
            <begin position="17"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="18">
        <location>
            <begin position="23"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="240"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="332"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="252"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="366"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="391"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="413"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="436"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="451"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="474"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="487"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="606"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="641"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="664"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="678"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="713"/>
            <end position="735"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1888121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="735" mass="73942" checksum="E92304C7F6232ABF" modified="2025-10-08" version="1">MKTFATIVASASLVAAQGYMTGCSIGNQNFKFTNVSSTDSYSNVNDDRISRYTTGTIGVKDVTSPDMQCGATGGKRTQGAPESAKIAAGETVQMHWSKWAKFNKGPTVTYMAKCPDAGCQDYVPGTDAVWFKIQEAGPTASGQWPSTSLGTSGSQDTYTIPECLASGNYLVRHEAISLGGSAQFYIGCHQLEVSGSGTSNPTDLVSFPGAYKSSDSGIKFDPNTLPPSSYTVPGPSVFTCGGSSGSTPPAVGSSSGPKPSTGPSSAVSSNSPVGPSDVPMGTGNTPKVTGNLPKGTGNVPLGTGSVGSNGGSVTTPAYGYQTVASASVSAAATTPAPGGEYGAEDVSSAPVGAKSTYVPVRGTGYATSASSPVTTSSPEDTEDCPVENDSVPASPTSSWVPLPGTNSTIPDDGSTTAGSSPLTTGSSGSGSGSDYESGDDDECPVEDEETAPAGSATTASSPASTGSGSTTPVESDDECPADDSEETTSNSSPTTPESKTPAGSSPSSSSSSTGSSPSSYGSKTPTSSSPSSSSSSSSTGSGSGSGSDSYSTSNTESTSNTPDKNSYSTESGSGSGSTTNPSTPKSSTTSAASPQSPATSSSTSPENDDECPAEDEEPVEEDDECPAEEEEPATTSPVETQNDDECPADEEEETTSNSSPTTPEENDDECPADEEEPTTTTPTSPATTSGSASTSGSASTSSSSPETEECPVEYERDLSYVEENLPRRHWDRRSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ00</accession>
    <name>A0ABR3YJ00_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8035 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000294">
        <property type="protein sequence ID" value="KAL1887827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058348">
        <property type="entry name" value="DUF8035"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42081:SF2">
        <property type="entry name" value="NIPPED-B-LIKE PROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42081">
        <property type="entry name" value="ZINC FINGER PROTEIN DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26118">
        <property type="entry name" value="DUF8035"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8035" evidence="2">
        <location>
            <begin position="405"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="473"/>
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        </location>
    </feature>
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        </location>
    </feature>
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            <begin position="729"/>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF26118"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAL1887827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="809" mass="90649" checksum="670CCE4C6C3D7788" modified="2025-10-08" version="1">MALAMDIPTSTTRTIAALDNSDVLALALFHRVQALSSVTSSSTPPTYLSSFSQIITRLHTVLASLRTEAADEQSPVYSTDTAIQLDGILRACTVALGYLNNNFEKLNTSWDARLGLEESISDYVLQIQKYETILHNILDDVQDRRAAKRLITAPIRATDELPQKDNPAQHVQQAQNEQDETALSEIRRHIGRIALKFLERGDSGLETVGDDLWSKVRAQLFKDGLSSQVVDKNSVSLRSFFQSIQRSFDSHPTITSSPNIGLSTYTPPSSPLPSTTKTRRASISYSSPYLYTEESYLFLEDFPLSSSPTTVSSSLVTQPLSTMTTMKSHTRALPMRDSRRSITTADVEYITTEDLTRLASRSNPSSISKSIASLSLQDRRASHSGRSSTVPVGPDQFGSPIAPAALWTKVSREKFTAEAFRRSKKHFEAFPSFIAILGFIGDEELQRLSDLSNEIRQSRMLYAIPSHKAVIRNEKGSLSKENSRSKQRGYHGEHQHKRDYAYAEEIRPRRKEHDSKSYRDRDTSYHDKRSQPHPISSNQSRNRTSSMSLVMPGPQSRDSISRPKPTIVSPPISSSGITNPNMTLTLRNGSASRSPTRPKSILKNANPHDVVYDSYSNPSEVPSSWPRQSHVPHLEAAIRASRNSTTEHSDCGSHTSSNSERERRRQSHRSGSERSSSSDASRERYNYGSGKSKDNLRPNKPRNEFYTVALGNDANKPPSARRNSTMVAQHDEPRRSSVAHREGRDSISSEPRRSSRASSDEYDKERGERSRQRDSRDYSSAPRHVEHDGRDHRKERRPSLLSAMKDALH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ05</accession>
    <name>A0ABR3YJ05_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_006274</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000275">
        <property type="protein sequence ID" value="KAL1888168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013726">
        <property type="entry name" value="Mitofissin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28075">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28075:SF1">
        <property type="entry name" value="DUF1748-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08520">
        <property type="entry name" value="Mitofissin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1888168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="61" mass="6822" checksum="C6DB02E097E1CE16" modified="2025-10-08" version="1">MISAVLAGMRRSTGLTFRSDKISGDNKDLNGWVDRYLGVGEWVMDQSVAIAGASSWFERRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ58</accession>
    <name>A0ABR3YJ58_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">SAM-dependent MTase RsmB/NOP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_006210</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000265">
        <property type="protein sequence ID" value="KAL1888354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1170">
        <property type="entry name" value="Sun protein, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049561">
        <property type="entry name" value="NSUN5_7_fdxn-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048889">
        <property type="entry name" value="NSUN5_RCM1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807:SF4">
        <property type="entry name" value="28S RRNA (CYTOSINE-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21148">
        <property type="entry name" value="NSUN5_fdxn-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21153">
        <property type="entry name" value="NSUN5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="7">
        <location>
            <begin position="132"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="329"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="578"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="345"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="578"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="449"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="238"/>
            <end position="244"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="638" mass="68164" checksum="2FAFBF3233E6DEEA" modified="2025-10-08" version="1">MSLYYEAADVLRTLDTAPGSLKNRVFNRKDLKSSAAQVYALAIESCKWSGILREVIDATDLLKSERKITPVLALLLVHDLLLTKGGISLPASHGLRAAIERHKGRLASELTRARIRRKQPTLDALRQLVEQENKSEDAGYPRWIRVNTILSDVATELQTTFKGFTQVGSVTEVMAAAPGTAIHVDEHIPNLLSASPGTDVTKTEAYRTGRIIFQDKASCFPAYLLDPMPEHGDVIDGCAAPGNKTSHLAALLWDRRGEAQAANVKRSLVYAYEKSRQRSEILTKMIGIAGAKDIVRIAFGQDFLQTDPESMGFVGSLLLDPSCSGSGILGRDSTPTLHLPTPYEKLAPGPGKGAGAKLKPGATKDTVNSSSKKRKRPASDAQEAQAETADDPSAAAERVLLDDDGNPVFAASSAQELDARLRALASFQLKIVLHALSFPGARRITYSTCSVHAEENEGVVRAALASDVARRRGWRVLSREEQIRGLREWPVRGDKAAAGGDEKVAQACIRSYRGDGRGLMGFFVAGFIRDGDGCGAGAEAEPFVRDESGMIVRQSGTGMPLLKKTGEFVELLEGDELEATATEDSDDDSESESESGSGSGSDDESGSGSGGVGASGDYSGDESSSNSDTDCSWAGFDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJM7</accession>
    <name>A0ABR3YJM7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000258">
        <property type="protein sequence ID" value="KAL1888505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="455"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="467"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="496" mass="56170" checksum="C2F23322E22FE88D" modified="2025-10-08" version="1">MPSHNASPSQTPASTHRWMHEWRTKKTIDIKPPRPKGPRSLMAMTLEVFCDNIDSLPDIPTGSNLPTRPLYLAYKEIIKTYGLTFHAFKVFSRVFGDFPTDSIPISTWMFVIHACEPDGPFSKVARGLSSYSLDFLAHIVLSEGASVTESEFMQLGRMPNLAVLEFIVPWSHFERLQPDSSRLLPRVTDRMFRGMANQDNPFPALRILKLWGPHEVTPRALAYMAKFPSLVLVDLVCMTSANFDVGDSPAIMAGWTREPMLKWRHLLADVSLLCHNGDDVIDDIQPAKVSAICENLGLWIFSARNKSAPQKVYKLSPDNHGDSHVRCLPDSLKEIIRQDPPTEQCHVMDDCIEDCRSCMDDYWAALMYTSLGQANTQNKDLEKLDSTFEAGQNIVYLKALGVKVPVPPKPFVTMYLGHPGRRKNRYSLKTTEVYVPKEVTGRRIYTRKYETIGKPQAAAQLRHSRPMTHNTSPQASSQPRARKRIRLDEMLKSFAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJT3</accession>
    <name>A0ABR3YJT3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006283</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000276">
        <property type="protein sequence ID" value="KAL1888127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046147216" evidence="2">
        <location>
            <begin position="21"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="303" mass="33813" checksum="947B381D45DE67B9" modified="2025-10-08" version="1">MWKLPFLSITLALSHFRGHASDSSSNNQPTPANGLGTGEAFAAPKTNEFEGLQPSVASASGNLISPHYLDDNGYTDTDLYGGVIGIYNQRYHQDKNEVLQLYIDPETQVITIFENNLNQERLRGKGRRLELHEVIQALFSKRDMDITTIKWVATLVDQAYTLKTINNYRKKKNLSPQEDLKITPTDYSWHEFSDLRYYKSISQIVPGAQVDRIISKYQDLPKLDVSQQPLTPEVMALSFNMPPNGDSDAIDPIDENAARLAAEDNLNAGLEAANAALMAYTKNIWKIVDELENQASNPTPGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK29</accession>
    <name>A0ABR3YK29_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_006117</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000255">
        <property type="protein sequence ID" value="KAL1888572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1888572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="174" mass="20369" checksum="E9551784476F2FD5" modified="2025-10-08" version="1">MDKTQPNGDSKIMWPEDLLRGGEITSLPLEDGRDSPNLLPGVFKHWESLLLAEVVCDFMMSKYINSQLERDKAREHDEEDSKKIKRIADIATGKAGINLMRVAICLLSVPETKIAQKVRGRVLCVLQKKKSTWRHQADDLIYFMRTWHETWHGKYFNDRRDETMVKVMRDVFQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK40</accession>
    <name>A0ABR3YK40_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000258">
        <property type="protein sequence ID" value="KAL1888509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011722">
        <property type="entry name" value="Hemimethylated_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036623">
        <property type="entry name" value="Hemimethylated_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032698">
        <property type="entry name" value="SirB1_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13369">
        <property type="entry name" value="Transglut_core2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08755">
        <property type="entry name" value="YccV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00992">
        <property type="entry name" value="YccV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141255">
        <property type="entry name" value="YccV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="630" mass="72230" checksum="C0B413892A347DDC" modified="2025-10-08" version="1">MAQFDDLPNELVQLILTFISAEDNLRNVQRVNRLLHMLGSDPRIWRYHCSLMRYWSPHHSIEEKFGLSLAEVDWKRLYLLRRRRNAEAEYLLSSAISNRPGRMMRLEQVSVLGLDVKQYLLDQISLNFMECHDALARKFHADVSLSSMHRAMGIARCLRLGPHKMKETQVESTTRAIKHSAKEWNRDDLEGIMTGLDMFALTSNERDISWSSTELDRYAEEFRRQNSEFGQLSYREKALRLNKWLRRSGYTGNKPIGKSFSHLRCAYLGQVLAHEDHMANPLIQCVIYCCVAARLDINADCCLFPGKLHVIVRAPDGEYLDGPFPRKIRAIGDEDRFLVDMFMSPCDSDSEISFSDLRQSLVSWGINSSEDGWLEPMHPASVALRNCRNIASSCERIHRMTPNSASEACSLMTNNNYHNVLLASYASLWIRAVLTPTWDVSWKQCVLELVETVRASWPEDYWIVQRFCPPFNGLGMSRTRAGTHSMITTLTPYRPSEIEQQRDQMRIQPTYRDARGGPAKYHVGQVFEHTKYGSIGVITGWIEDRSLRGYIPSGDRDSGTEADEIKTIFYYCLAGQNALPALVSEGNIRIIRNLVKVPTELVSRCGKYFTNIDVVKGEFISNIKDAYPDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL35</accession>
    <name>A0ABR3YL35_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_005929</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000232">
        <property type="protein sequence ID" value="KAL1889044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF49">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="4">
        <location>
            <begin position="276"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="22"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="595"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="760"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="616"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="639"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="781"/>
            <end position="790"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1889044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="790" mass="89507" checksum="89CE7D448B440CB3" modified="2025-10-08" version="1">MQDRIDRLEGLVLSLMHNGAHMETLPSPPLRDTQRPSSHDGESINSSPTPKLGFIEDSNEYRHLTGSKNGGSPGLLKVDTRGGRSMYVGQQHWYTILSDISEIKAYCVTHKREFERGYSAVMASKPAFFRDGPLLLRGAAPAAPEELRNSFPPKGQVMKLVDNYMASIDGTQTMIHKPTFTAQLQKHWDSPHETSLTFLGLIYAIMSLSLITYSQAKNEPVEFKGCAVDLATQFRRRTIQCLHATDYTSPGEYTIETLLLYMLSELLTRWEADIDLYLIMGTIVRLAFRMGYHRDSKWFPSLSPFKAEMRRRVWAFVQMTDVLISLQVSLPSMIDNEECDTQFPTNIRDEDFGPETRVLPPPRPWTEDTTINFMIFKSMLYSELTDIVKCTTRINKKVTYEQILCFDERLDQIYRQIPDQLRVCPPNSNDPTVSFMRKYNLEITYQKIRCFLHREFAAKARQNPRFNHSRTVAIEAALASLGHLATLHKATLATPNLVQIKWYVQSSATKDFMLPAILVSVDLHHDKETKESSRNVNSSATSGFWTKRQRQNMLRVLEFTRKIWTDCADHSIDAFKSSHVLTVLLRSIQVKSCGSEPESRAKSYPSSGREDDHVHTPSTVHSENTDYSRLSSLAPDSRMATSDPTPSIESVKIPPHPGRSMEYAARQSNGHTSENCPPPNVAAPVYGGIPELGAPNIQAEFLNGPINMDQYSMNISSPFAYMLNNMSTQGAMNNIDWDVFDNFTQSNAAMSIEPSFSMYAVAPPPPPSQRNEARNMEPHNNPHHQNRQLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM30</accession>
    <name>A0ABR3YM30_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005824</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000220">
        <property type="protein sequence ID" value="KAL1889351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053268">
        <property type="entry name" value="Woronin_anchor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40641:SF2">
        <property type="entry name" value="INVOLUCRIN REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40641">
        <property type="entry name" value="INVOLUCRIN REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_2G08060)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="197"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="450"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="550"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="805"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1290"/>
            <end position="1313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1337"/>
            <end position="1356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1480"/>
            <end position="1577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1715"/>
            <end position="1811"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1975"/>
            <end position="2014"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2037"/>
            <end position="2196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2292"/>
            <end position="2319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2384"/>
            <end position="2414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2504"/>
            <end position="2686"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2700"/>
            <end position="2759"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2772"/>
            <end position="2791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3313"/>
            <end position="3348"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2897"/>
            <end position="2960"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2989"/>
            <end position="3023"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="10"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="131"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="219"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="451"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="586"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1525"/>
            <end position="1535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1558"/>
            <end position="1570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1782"/>
            <end position="1795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="2115"/>
            <end position="2125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2129"/>
            <end position="2145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2384"/>
            <end position="2397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2398"/>
            <end position="2414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2519"/>
            <end position="2541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2601"/>
            <end position="2612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2669"/>
            <end position="2680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2710"/>
            <end position="2722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2737"/>
            <end position="2754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="3313"/>
            <end position="3331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="3348" mass="365323" checksum="394A87D4C050BFBA" modified="2025-10-08" version="1">MSVGGDGDTDNGSSSEGQTNAEAAAVHVAAQSDKTEERRSHRRKDKNKDKNPGAATTVATAADFDVEPTLTHEPQVRAIGVRGTCIGENQDREYHMEEQDDQEEKETGGREQNEGQQHQVEDAETNHSVVMEEESAYADADADADADAYAHETPHAHAYAHAHAHAHAQVDGPTCDSAASTPRAATQPSALHLDTVYDANPYSSSPSIPDLIRPRDNSPSRTTSNSISSKDSEYAGHTHSSPSGATHDIGASRLDESCPIEQESVGTETVDDAPQIIDEDANLTLVGKPLQEFPNPTQDNLTELACALPLPESPILDASTIIQHSISDLESNSPVVSSTHLSKAAFENEIGCGIQTTTEDVSIGEEFMTSVAIDGNAFESEITPSLPIALTNNPVARPNEKLGLELSSYVLQDLSLQEQELASQKTCDSPLGRVSEEGVAIDKKVDYFTEQDASSASPTNDSEIHAEEVPLPEAEVDDFEGHDKKERELDCELVIIKATSNTEFYAPEQESALQSLPQEPDAAIHTKNVSSPLAHIAVDKHRIPVVTVGSLPTNDPLPVAEAASASSGPIEEVGRDATHSPTLSRGQRRKRERKRERERKRKDREEVLAPSLAIASEPVASTEIELHEEKIDNSLEQNVVTPIYESLIDTTDVGFIEEETEGLGNAILDPELKPDTTALAPGDWHEKNVLDEVLIASQLALPDSDYSDAEAELGRDSIEIALSHEEAESDSTADGTSIHDSSITEAAANLGAQPVFEIEPILGDEALSGGSVSAGGEIISCPENMSADSIPCAIVASREPEVDSHEAKAVPVPEPTSEPETRDKSGAVPKVLIHPDTQFAFEEVLLPDITPENIPLPKNQMSEDEMFEEATTPIIHKSSCDIEASLVESSRGFEKNVLLFADVIHEPGQVDFNPGLEPADIPLPADSFDTDDEAIEREIKVRVDTKAVAGVELCNKPINGAASNYDVPIDSTRESHDIPFGADAYRDLYLPDTSCYSSESCANSDSDSELCDDALAIVAASEHVSINHVEAQEDVSTEEDQTSVLGQNAEEVLSIDKNTEGIDGVFPVVAEFGTEEPLQSPNAQLEYCDEDHMTPGDAFPNDPEQLSASSSRGIEAEVAVHVDPTLVPLPFDVQDLGVDGESSQKYVELEPESWLSLFRGIPDVIDEYEVPKAQVAPEMLTEEREDTLATNEVIVVSAIEDDHVLIERLEASDNSGPLSCREAPVAEESFATETPAIFEETFVVEETHSTERMTEIPESTHVNAVSSSEALLPTDEELLGPEAIIEEPSVFDEPPIPQQASGTAETGPLEEPVLEDPTVPETLFGVEEPYIAEIAASVVAEDPPNEPVSDGKSIPAMDIPPPLSLQETTEEASAIEISPIIEGLEPIVTEEAQEKCQQVSEPSSQPTLVPSFDFAKNLLATMPWAAGLGFAASGKNNIISESSLLAETAVDATVSEADEPVATLEEPTVVLNPIAQAVEPESQPPAQKYLEQPPNTTEPVLGTTPKIDTQQDTIQGVRDDWMPRKNSKRRKKRNNSRAISPSLARDVTGAAEAKDTPVTEVTESAESTSTRSLDGRTPPKVTQEVLAVCTTSETKRSTSMDEVSLLVAEDTVNSDFNSGHDSVVSTTAAPMVPESDLSKTPRLGTESLIFTELNEPKFDDNFLDDSISFSAPTSVVAESFAQSEGNSTSLPQFSVGTLTVAAGATTLAAAVSPIKDTSEQITTENASEEPIPPVLFTVKKPTPSTSRSHTPDHFPDSSNARKKIPASDYVNDSWMPKPNVYRQRRNRSRSRSRSRSRADIDMSNADSGKENLITSATNSRGRLSLPVSLPTESETVDIENSRSLRIEPHVLDTPAKESALIIQPPVPVASAAVLTPVETFEGILTKDNISVDTSSFLEKQVSTNKNTAASTWNSSSWGFNRDNTANISDSGAEAISSQILLTIGGEGGALESPTKESLQPTEFEPPAYNLESLASKRASQEVSQKVPQETPREAPEQISEEQISVAARKKRRSRKTLPLNAESIEDLAKLTVEALEEHARQNSAPPSPDRGPSFTMISNDAISELAPMSEIGDLPGPAAPQPVAEPSFSYTPMSPLLETNEHDEDLDFPSFYTKRSNKRRSRARRSLLIDSQSVAEVPETSDTCTTPPPLATEAVTPSKTMKKTLRPRDKGKSTESVISETPPSPPRLNDGAFSVLPDFDDDCGSENYGYPHKDRTANMSFLTEISETDSLTTAYTAKESQWWYNKDLGASQSGKPLVARAPLRVPDPCPRVSSPSLSRPASRQQAYLHSLRAPEGEKARGPNTSEKAPESHLGLRRTGSTISNRSFEIEQASKAVNWRQSSLVRAAEIATLSTSLAGGVSNLASKFVSQTTTEKDNIPAIATTSLSRSGSNMSLQSEKYKLDDDEEKGKNEDEELALDKVEMSSEEQLKKKEEMQLSCAKDLIARLKAQDRTQDVIKRAESPLPLDHDDPRGREASMLPSVAAVERASHRDRDSVKLRTVPSHFDLRDGSSCDESLDNHANNTTADSESTLTMRSPTRPTSYILPPLKEDPKEPSSGAVPGALTPRRTSRYSLNRPASPFDRSITGSPLLRDSQSKAVEDSNSNEQTTTLRDPTAGNAVPRVASPRPRNSMYRDPEKKLQHSPFQERTFRDSPLRRTPTLREPSPDQNHVEPQKNKDAPMPDPINRRLRFNQRVPPLDPESLALDLAGSSPAAATPAPTSARSVSDSFVPRPLDRSATTSLTATTNMPTSISAGQLPVARRSISNTSLVRQSTLPLAPRPGSSSSTANVRSLRLRRTDRRLTAGLRGSQSHNDLTLNQEGTEKLEDFRSSLYSIRAAEDGNSDPIANEGRVRAKEAAKDEAESERECYEGLGDAQMGSPISSVRPHSMRRRQSMQVIELTNHVNQLIEENQALMEERQNFEVGIARQAAAVLTERNAEIDNLKHTLIQVRKELSRIREVNSGLKDANNRLSTKNTEATREIERSRAIHEDVDKAIQERDQEIANLRSQLEESRARIRELQAQILASAGAPETYLHIFNEDHFDTRCNSLFQHIQQWVLRFSKFSDMHICRPTIHIHDEKILDRLDNAVLDGTNVDHYLRDRVKRRDVFMSVTMNMVWEFVFTRFLFGMDREQRGKLKQLEKHLSDIGPPVAVRQWRAITLTLLSRRENFRKQRHQDTEAVVQAIILTLSALLPPPQNLQAQIQTQLRRVMHEAVDLSMEMRRQKAEYKMIPPPEPEYDTEGELVEPVPFRASTMHIVNSSKFTETPEQIEARGASVRMVLFPLVVKKANDAGEGDEEIVVFPAQVILYQPRKASNSTAQSSENGGVSVHSQMPPDDSQASVERENGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMI5</accession>
    <name>A0ABR3YMI5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_005798</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000217">
        <property type="protein sequence ID" value="KAL1889398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1889398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="94" mass="10221" checksum="5C17B7A4DFE78F9F" modified="2025-10-08" version="1">MFGPRVSAAVQCQDSAYSIPKHRGHLCLQYALLEKDSHGEPCALDINERDFIAAISTDNIAILQAMVAHTGSGISVDHFVKAAQLDAQDLPRPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMZ4</accession>
    <name>A0ABR3YMZ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sister chromatid cohesion protein pds5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PDS5</name>
        <name evidence="7" type="ORF">Cpir12675_005757</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000214">
        <property type="protein sequence ID" value="KAL1889517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19953">
        <property type="entry name" value="PDS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039776">
        <property type="entry name" value="Pds5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12663">
        <property type="entry name" value="ANDROGEN INDUCED INHIBITOR OF PROLIFERATION AS3 / PDS5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12663:SF0">
        <property type="entry name" value="PRECOCIOUS DISSOCIATION OF SISTERS 5, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20168">
        <property type="entry name" value="PDS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1292"/>
            <end position="1491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1300"/>
            <end position="1309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1325"/>
            <end position="1345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1418"/>
            <end position="1432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1433"/>
            <end position="1443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1453"/>
            <end position="1469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1491" mass="166448" checksum="CEAC723ABBA9C221" modified="2025-10-08" version="1">MAPARRSRRAPPKEPSPVPSLSPDLSDPEEVPEEPEQASSPISDPPSDVEDLDSAINGRDGVDNDDDGPKESLQFNEQLSWKPGKPIPVSTLIPRLRRLLDELSDMDQERVDPESLTDVAASLAHRNLLQHRDSGVRAFVAACLSDVLRICAPNAPFSSDQVNMIFSLFIRDIIPALKDPGDTYHAQHKYVLVSLSEVKSILLVLEIEGGDELFLRLTSACFDTISILSSQDAEGNVPRDVEHHMTHIMITLIDESPGIPALVIDSIMAQFLRALPPGGLKNRLDRSDDSSQSNLLPKKIPAAYIMAKNICTDCPEKMSRYVSQYFSDVIIDATSLSRGQNEDEEEAPVAPSESDLHNIRQAHHLIRELWRAVPIVLQNVIPQVEAELSADNASLRQLATETLGDMISGIGAAGPPPPPIMDPCQYPQWRMDDELPVHPSQTVLNSPSAVLSFSQVHPTVYHSFINRQNDKVSAIRAAWALSVGYIISTSAGNTGISREEEGKLVQALSTKMLEYDEKVRLAAIKAIDIFNIKDVVNKLGYYGGVEQEGSVLAILADRCRDRKPAVRVEAMVLLGKLWSVAASEIAAEHDLVCPCLGGIPSRIIEVYYTGDPESIAILDRVLLEYIIPLGFPPRKSKKNSQTAAINYDSDKVRAERILQLVRSLSDKAKRAFFAMQARQPAMMPPVIAYIRQCELYNGGVIEANEDRVTANLNGVIKWLSGRLSDQPKAQADLERLAKVNERRYYALVKYAIDINNDFKTIHDAIRELVKRVNGEGKCAGVMDTLLPLIYQTACITFNKSHLASFMEFSQSNKNGLGSAAHEVLGEISQRNPAVFKSHIGELCKSLVEQAPTREKPNDPSVVDVLKACASYAKTETEDMPQDSKFLETMKNYALYGRPPKAAKYALNIILSSKDTEAEETARSILRRIMKEWKYGASNFLNHLACISQLALMKPNITEDYDKEILDMTIQQLLLQVKGEAKDTDPNWVDDGDMDEELQAKLLALKILINNLRATADLDDSKERIAAVFKLLRTLITKDGELCKTKDTPKYHRSRLVLAAAQLMLKLCCESRFDPHLNPHDFNNLAFVAQHGESAVRHRFVEKLQKYLATNELTPRFYTIIFLTAFEPVATFKERLSTWIDARARFFVERSKPVLEPAICRLISLLAHHPDYSNDSGNLIDHARYLLYYISHVVTEDNLGLVLRYVERTKQTLDAINPASSENIYVICDLALALLRKWQEKKGWSIQVYANKVGLPIGLFSALPSHKVAVEIAEKQYLPEGLEDSLDGLLRSVDRKKKRKTADERHDQPAKRTKSVKLPSREKTSKSRTKSTPRSHSAPKKSRKSRTRDQWGSDVDADFEGPGREVGRRKSGRSRSGRTSTYIERDSSEDDEEMLDGVAEWSYLDDNGKPKRAMPKNDEESEEDEDEDEDEDNLTTPKKSSVANTKKPAAKVNGNDTDSSLSEISDMDVNSSDEADDGAEQAPVQKRSARRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YND3</accession>
    <name>A0ABR3YND3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005837</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000221">
        <property type="protein sequence ID" value="KAL1889346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="538"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="597"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="648"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="458"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="675"/>
            <end position="687"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="709" mass="77227" checksum="F7754250173D5385" modified="2025-10-08" version="1">MNWTEGNLARHARPQQRHSSDVKQKKHFAKLRAGMTSGIAELSSKSFNFLPASSRPLDLPPPPLHSSTASPPRAQIDASSRGPKPNMATASSTITSNAPLKRRNCASGDVEAPDINDRRKRLLLSSDWVGVGRPSTDSQHAKSQFPRSSMDSESSRRQSQNALPRISAFFVESKRRSRSPVHHFGLVSDVGEPRVHIGNQSLRGTSLYSAAQSFQYSPPSDISNDWPSYSSHAPMDCQMSSSRWSSPEPPQCYVESSPIPVHQPLPQRHRKLYEAHITEEPPENASSSAAIMGKSLSSSVCSDPDVIGEWKAFLGFSNPSGDFYSTESVSQHEECIYESVESDEPIQLEQHNHQSHGPLVAASGTPSIAIPTPRIVDETEPFVLSSDPDSGILSSPAWISPDPEPQQYPSITDGASALPEQERVEIRTVRLSFSGVIYQSGSPRKSWPATTRAKRQHGQNSVESMHIQPQSQADAPQNKTPVDELQKILPASAEQQQDDTCSEDGWMAFVFGSKNCDRKDEDALEEAVKQTSRDLMNLGSMDSDAANRGSPQPAKSTESWERGVYRHFSPSTSATDLAQAAESLPSTSDRLQISLPQSEAPWKDSADTISTAMPSDDISTHAQQGSPNGLAEATSAFRFSHPKLFVGRLSSAPNTASKVQVGGSRPSAGDDGGKDHKRRRVGSAKRAKSTDGRPDIRSLPNFEDDPIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNK9</accession>
    <name>A0ABR3YNK9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">PH-response regulator protein palH/rim21</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RIM21</name>
        <name evidence="8" type="ORF">Cpir12675_005589</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the palH/RIM21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000199">
        <property type="protein sequence ID" value="KAL1889943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014844">
        <property type="entry name" value="PalH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35779">
        <property type="entry name" value="PH-RESPONSE REGULATOR PROTEIN PALH/RIM21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35779:SF1">
        <property type="entry name" value="PH-RESPONSE REGULATOR PROTEIN PALH_RIM21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08733">
        <property type="entry name" value="PalH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="311"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="393"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="492"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="743"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="430"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="510"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="553"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="743"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="797"/>
            <end position="811"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="811" mass="90062" checksum="0B05D3C42FD5932C" modified="2025-10-08" version="1">MASLHPIAGSDRGLHHPTAVAATVDCSQPILFQNNILSYANGGIIRNLGRAASYVLECSSPHLHSPSRVNPLRPRSTVDPSTVTIPSSTDMNDPFYASKFPVMYALAATTVTAYMLVIMLFITPRSFLDGGIVYLGRRGGFTSGSTGGINIGGRPWLQKVAAISVAISLTIASSSTFDVAQRQYEVGVLNTKQLQFEVMDGTELKVIRLISDTFLWLAQAQTLIRLFPRHREKVIIKWTAFALIILDVIFSALDSFKYNSTASSRTHPRTFVDAIPALSYLFQLSLGLLYAAWVIYYAIMKKRYSFYHPLMKNMILMAMMSLVSILIPVVFFIMDIVNPEFTGWGDYVRWVGAAAASVVVWEWVERIEALEREEKKDGILGREVFDGDEMLDSSSSVYRRKRSSGTDDDSSEKRLPNTRTQQTWSSALRSQRRLRRLSRRHDEPPTTTVPAPHRDIPLGDSPWLQRPPVAVTPISRTDTTSVSSTVYTVRRPYQSETPMERVAEDGPPSRGTSPTRSQWTADDQPPPALLTINTSPGAGAKESTATITTTHTSFNSQNLRLRETSPTVPTEPQSTTATDLEANNSDNSTEGRRRRRLAMPSFNDLATPILSRSSAQDSSTVQVFNNRTEETRPSHGAHDDIGRWDIRGRFEEFAVSQAEKIRERFRPQNNFEELPTFDIPAPQRMGEPLQQLLEEEEQQQQQQSDRRRSRRPVYSLFRASSGLGIQQQPNGLDVLGRSISVTDHANPNSQTVHSLGSATSPGAYERLNSSSSVMSGVRQEAPPMWPGVHPRVEADDSASGPSSSSAGVTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNN2</accession>
    <name>A0ABR3YNN2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">Cpir12675_005609</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine = [(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9595"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="EC" id="2.4.1.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:16638"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000201">
        <property type="protein sequence ID" value="KAL1889921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14879">
        <property type="entry name" value="MYSc_Myo17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014876">
        <property type="entry name" value="DEK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036037">
        <property type="entry name" value="MYSc_Myo17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF45">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08766">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109715">
        <property type="entry name" value="DEK C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51998">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 16" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="8 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="12 16" id="KW-0505">Motor protein</keyword>
    <keyword evidence="10 16" id="KW-0518">Myosin</keyword>
    <keyword evidence="7 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="855"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="895"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1167"/>
            <end position="1186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1562"/>
            <end position="1583"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1589"/>
            <end position="1610"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1617"/>
            <end position="1640"/>
        </location>
    </feature>
    <feature type="domain" description="Myosin motor" evidence="20">
        <location>
            <begin position="1"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="19">
        <location>
            <begin position="918"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="domain" description="DEK-C" evidence="21">
        <location>
            <begin position="1765"/>
            <end position="1820"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="577"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="580"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="17">
        <location>
            <begin position="597"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="607"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="98"/>
            <end position="105"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAL1889921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1823" mass="202477" checksum="5474B63B24CA0479" modified="2025-10-08" version="1">MSAQANGGPSQASLPSLPAHLQSDTQLTAHLASRFYANQPTARLSSHALIALNTYTSSSKGIDGGREGSTQAGAEEIADRAFTRLGHRSENQAVVFLGESGSGKSTLRSHFLSAILNKSSTPLSSKVSLAAYVFDCLTTTKTATTSTASKAGLFYELQYDTATTTNPVLIGVKLLDHRLERSRITDVPTGERNFHILYYLLAGISDAERSHLGLDSPESAPMRWKYLGHPTQLKVGINDAEGFALFKNALKRLEFPRSEVAEICQILAAILHIGQLEFETTSNTSVTADDSGGFSHEGGTTSTTVKNTDTLGIVAAFLGVSPLDLQHTLGYKNKMIGKERVTVMLDPVGARSHANELARTLYSLLIAYVVENINQRLCAAEESIANTVSIIDFPGFAQHPSTASSLDQLLSNAATEALYNVTLNNFFERKAELLESEEVTVAPTSYFDNSDAVKGLLKCGNGLLSILDDQTRRHRTDLQFLESLRKRFEGKNSAIIPGPATAKLPGSNFLTENTAATFAVKHFAGEVEYSVQGLIEENGEIVSSDLMNMINSTRSEFIARLFGQEVLQTVNHPQERSAVMQASISSKPSRQPSVMSRKGRGRPALRGKKDESEKDILKSRGSEQGASGQFLAALENVTRAVNDIGTNAYFIFCIKPNDRRIANQFDSKCVRTQMQTFGIVEISQRLRSADFSLFLPFGEFLGLSDGETMLMGSERERVEFVVDQKRWPSNEVHVGSTGVFLSERCWMEVANLATAPAGGHYPAASDNGDHVQPRHDAAAFAASKERLLSGSSSPQYGEKKGYYGDDGRSEAGVSTFGNGDMFKNHETREQMLERNEEKKMDEVEEFRDSASRKRWVVIVYAMTWFVPDFLVRVVGRKPRKDIRVAWREKLAINMLIWFICATSAFFVVGFPLLICPTQHVYGTAELSSHNGDGNSAYVAIRGFVFDWGKFMPRHYPSVIESRRLLSYAGTDVSGLFPVQVSALCTGINGNIDEHVALTTRTANLTGAANVVGDKDNTYQFHDFRAWTNDSRPDWYYEQMTMLRSRYYKGRVGYTPKTIKRLASSGRQIAYIGDDVFDFTEYNSGGGRTYQAGTGEEVPDDALTQTRFMSDKVLSIFSSAAGGDVGEYWDQISLSVTDKANQWTCMKNLFYVGAVDSRNSFRCKLSDYMVLAVSIALCIIIGFKFFAALQFGGKKVPENLDKFVMCQIPAYTEDEESLRRAIDSLARTKYDDKRKLLVVVCDGMIIGQGNDKPTPRIVLDILGVPENIDPEALSFESLGEGMKQHNMGKVYSGLYEVQGHIVPFLVLVKIGKPSEVSRPGNRGKRDSQMVIMRFLNRVHYNLPMSPLELEMYHQIRNIIGVNPAFYEFLFQIDADTDVAPDSCGRMVAEFQDDTRLIALCGETALTNAKSSIVTMIQVYEYFISHNLAKAFESLFGSVTCLPGCFSMYRIRAADTGKPLFVSKEIIDDYSTIRVDTLHMKNLLHLGEDRYLTTLLIKYHSRFKTKYISSAKAWTIAPDSWAVFLSQRRRWINSTVHNLMELMPMNQLCGFCCFSMRFVVFVDLLSTIIQPVTLAYIVYLVVLIATDSGSLPLTAFIMLAVIYGLQAFIFIVRRKWEMIGWMIMYIFAMPVFTFGLPLYSFWHMDDFNWGNTRVVAGEKGKKIVISDEGKFDPSSIPKKKWEEYQLELWETQTATAKDDARSEVSGYSYATKAQGPMSDYGGGHLGGSTYGLPQYGSRMSLAPSHIDNRNSQYGGSQFFSPEDMVGLPSDDAILAEIREILRTADLMTVTKKGIKQDLERRFGVPLDAKKLYINSAVEALLSGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPF8</accession>
    <name>A0ABR3YPF8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Solute carrier family 28 member 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_005648</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000204">
        <property type="protein sequence ID" value="KAL1889783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008276">
        <property type="entry name" value="C_nuclsd_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011657">
        <property type="entry name" value="CNT_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002668">
        <property type="entry name" value="CNT_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590">
        <property type="entry name" value="SODIUM/NUCLEOSIDE COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590:SF4">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 28 MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07662">
        <property type="entry name" value="Nucleos_tra2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01773">
        <property type="entry name" value="Nucleos_tra2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="327"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="414"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="450"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="510"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="542"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="domain" description="Concentrative nucleoside transporter N-terminal" evidence="8">
        <location>
            <begin position="171"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoside transporter/FeoB GTPase Gate" evidence="10">
        <location>
            <begin position="252"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="Concentrative nucleoside transporter C-terminal" evidence="9">
        <location>
            <begin position="356"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1889783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="581" mass="62945" checksum="85805D6D9EA37514" modified="2025-10-08" version="1">MADPIHVSAITRKPSGSISSKHAPSVADPEKHAGIVEPAVEASSQSHRSGRFAIMYHRHKWAVHLFWGALFTAWWIVSLVLHRNDKNWVVPFLLWLSVMARLFFFYVSSSIVSNPIKTAWKKTAVAVYDRIPEKFRIPAGAAVTISAILIGTFCTDEWEDNNRENRAVSLFGLFVLILVLWATSAHRSNVEWRTVIGGMLAQYIIALFVLRTSVGYDIFKFIADRAGDLLSFSKLGVAFLTSDSVASLPWFLIGVIPAIIFFISLVQVLWHCGILQWFVSKFATFVFWALRVSGAEAVVAAATPFIGQGESAMLVRPFVPHMTKAEIHQILTCGFATISGSVLVAYIGLGLNAQAMVSACIMSIPASLAISKLRYPETEETMTAGKVVIPHDEEEAAQNALHAFANGAYFGIKIAGTIIASIMCILAFVGLIDGLLGWWGSYLNITSPKLSLELIVGYICYPIVFLLGVPRDGSLYTISKIIATKIVKNEYLAFSKLVATEGLSARARLIGTYAICGFGNIGSLGIQIGILTQLAPLRGGDIASLSISAFLSGILSTLTSAAVAGLVVSNQSGSVMKLMSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPG2</accession>
    <name>A0ABR3YPG2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Spt20-like SEP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_005666</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000206">
        <property type="protein sequence ID" value="KAL1889762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046468">
        <property type="entry name" value="Spt20-like_SEP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12090">
        <property type="entry name" value="Spt20_SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Spt20-like SEP" evidence="3">
        <location>
            <begin position="114"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="24"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="210"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="435"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="579"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="676"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="747"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="808"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1068"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="455"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="480"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="580"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="603"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="687"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="715"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="751"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="822"/>
            <end position="831"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1113" mass="123683" checksum="748DF230377B82A4" modified="2025-10-08" version="1">MASKIKRPTNSITAVNGAVTARATPLSSALPKKAQGTSTSGTAIPAPIVHQTPIRPPNIKIRQENSVQFQGRNLRNSAGLPSASLPAEPNDSRSMERLPYDISKKYILKKHVGKPPSLIVHLHPTYFRFDQQEGVFSYQSPMRIFLQHLKSSTIPHDLMIFFTQAGVSFYDGCLIVQLHDHRSTEQESDNSKQELAEKKAVQASIHNHNHFVTPSPYTPFPNDVTSSKNDDGGLQDESKEKAKIESSRSKDGADRLKIYTLVMLPTPATLSSDLLIKATTPANSAIPPTPIGAVPPTPTAIMPPQKRFKTERMELDGSNARQVEAGILLQTTPKLFLEPAKSPVDMIMLLEAFSHSKHSESVPLPKGRKRTVAEMAADEAFIADHERYMLVLDERLGPISSSAQNANSNGDADSSAASKTFERFARLADIRKAQEEKRAEEKAKAAENQRRVEQQRQQQAEQQRQQQAEQAEQQRAQALEAERQHAQKEAAKKKVQATNPKMRFQQQQQQQKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQQQQAQSQNMARTNQSLPMVSQGQQLGGQTQPQQSLQTVSSQGLTQTPTSTATQMVPQSQGTPQIPKSALPNATPTTSIITIPVKPIPASNNVMRFSGQAGQQMASSPVVRNGTPIQASSPRVGGVSMQQTGSNMAGSPSRPPSALQSHAVPMSVSMSARSHQSHGQGTPHMANATPTMVSARTPVVGPASAQTPRMSQASPPPTMMASGSAMGTSTMVNGNIQPPMAGNIRMAAQLAAHNNLTQQLNIQQQQQQHMANGMMNGTNQPMTSAQQQILQQRLLQQHQLAALRQQGIVPGLSPQQHQQQQQQHLLAQQYAMSMNAMQTGQMTPQMQAQIRAQLATRAQQQGMQNGNSNLQAIMLQQQQSHLAAQQQMAAQQQQQQQQQQMAAQQQMAQQFAAAQQQQQQQPQVMAQMQQLQMQQQLQQMQMQQQRQQQLTGLTPQQLSILRESTNAEQELIRANFMTLYRQQMTVITNKFGSMDNIPPETAEGIKKRCILNAQRAFATRKIQAQAQAQQTAQQLQQQQQQQQQQQQQQQQQQQQNMNAMMGQQGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ71</accession>
    <name>A0ABR3YQ71_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GMP synthase [glutamine-hydrolyzing]</fullName>
            <ecNumber evidence="4">6.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">GMP synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Glutamine amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">GUA1</name>
        <name evidence="18" type="ORF">Cpir12675_005751</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the conversion of xanthine monophosphate (XMP) to GMP in the presence of glutamine and ATP through an adenyl-XMP intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>XMP + L-glutamine + ATP + H2O = GMP + L-glutamate + AMP + diphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.2" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000213">
        <property type="protein sequence ID" value="KAL1889534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003922">
        <property type="term" value="F:GMP synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01742">
        <property type="entry name" value="GATase1_GMP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01997">
        <property type="entry name" value="GMP_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00344">
        <property type="entry name" value="GMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001674">
        <property type="entry name" value="GMP_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004739">
        <property type="entry name" value="GMP_synth_GATase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022955">
        <property type="entry name" value="GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025777">
        <property type="entry name" value="GMPS_ATP_PPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00884">
        <property type="entry name" value="guaA_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00888">
        <property type="entry name" value="guaA_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000848">
        <property type="entry name" value="PRK00074.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11922:SF2">
        <property type="entry name" value="GMP SYNTHASE [GLUTAMINE-HYDROLYZING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11922">
        <property type="entry name" value="GMP SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00958">
        <property type="entry name" value="GMP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00097">
        <property type="entry name" value="ANTSNTHASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00096">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54810">
        <property type="entry name" value="GMP synthetase C-terminal dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51553">
        <property type="entry name" value="GMPS_ATP_PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="8 16" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="6 18" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 16" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMPS ATP-PPase" evidence="17">
        <location>
            <begin position="213"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="240"/>
            <end position="246"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00044933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1889534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="541" mass="59757" checksum="6565E44E451C96AE" modified="2025-10-08" version="1">MASSGEIPEVVPHKTFDTILTLDFGSQYTHLITRRLRELKIYSEMLPCTQKLADLDWKPAGIILSGGPASVYAADAPHVDPAYFGLGVPILGICYGMQEIAYRSDSTNVVAGEHREYGHAELKAKAVNGHVDRLFKNLESEFKVWMSHGDKLSKLPEGFHTIATTPNSEYAAIAHKSKNIYGLQLHPEVTHTENGTKLLENFAVGICGVRQNWTMANFVDQEILRIRKFVGDGQVLGAVSGGVDSTVAAKLMQRAIGDRFHAVLVNNGVMRLNECEIVKATLEAHGINLTVADASKEFLEGLAGIADPEKKRKFIGLKFIEVFEAEAKKIEAAAAQTDKAGPIEFFLQGTLYPDVIESISFKGPSATIKTHHNLALPDRMKNGQGLKLIEPLRELFKDEVRDLGRQLDIPHELVMRHPFPGPGLAIRILGDVTPERVEMTRQADHIFISMIREYGLYDEISQAYAALDTSRAVGVMGDQRAYAHIIILRAVQTTDFMTATPYPFTHEFMNKVATKIVNSVQGVCRVVMDITSKPPATIELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ73</accession>
    <name>A0ABR3YQ73_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pleckstrin homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005562</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000197">
        <property type="protein sequence ID" value="KAL1890021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053005">
        <property type="entry name" value="Nuclear_Pos-Cytoskel_Interact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024774">
        <property type="entry name" value="PH_dom-Mcp5-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28190:SF2">
        <property type="entry name" value="MIGRATION PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G07730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28190">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12814">
        <property type="entry name" value="Mcp5_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pleckstrin homology" evidence="2">
        <location>
            <begin position="984"/>
            <end position="1116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="613"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="821"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1197"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1231"/>
            <end position="1309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1331"/>
            <end position="1392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="661"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="719"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="824"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="850"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="870"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="907"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1197"/>
            <end position="1207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1208"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1260"/>
            <end position="1309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1346"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1382"/>
            <end position="1392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1392" mass="153111" checksum="759668153EFAD4AC" modified="2025-10-08" version="1">MMAWETEDEYCSPTVPAGLPTPAHSDVPSRKNSRASRRAARRSVTPPGRKSSSPPIPDKSKRSSKDITTDETISILDPRRFTPTLHANLVSEILTLRRDQEEKIKLIEQLESALHVSRQEQEVLEQTVVNTSKETRAVKRQLSLLEGGTSTAIGDLAKERDEAVETSTETKKKLETAQRKIKAQEEDSQRVHNQWAKEKNEWEEERRKFERKIHISESRLKIILDEVAAYQAQQQSQAAQGSNSEIEDGTDRENDSASIRSQRPASVSNSVRFSIISNRGLNSLADELDFGGDDEWIEYDDRRESLISINNAFRHSRTFSKDSTLSMTKGHARTQSIQSIDSLRRPSSGARGTLLQSTPVIEAPEDDISVNGTITGGDEDLDILDIDESMADVTVLERPMTPPSEISIEYVDTGVQFSPPSSPKLEAIMGDVISIPAVAIKIKMTRASVVFSRSDAEIEANQRRKRVHIGPPLTIEPVSAVSRPMISSGSQTIEAPLSPPKTPVSPVSPVEIISIPPTPIVRVSRPFKPTMVISYTQTEPIPQRRIKIVPQQVSVAPLPIPSISIVPPSSRPSSPHESRLPQHFKDFGCQVNMPPPQMVTSSVQTEPIRIDKRLAQLPPHLRPSAIRSRPTTPDEGSTDDPRNFTPIPGYLPPRNPRRLASQRSISDVNSSPPAILLPSEMPVDAYPGNNDDGPLSGERAPMRRPHRISSLFAGFDGVSSDDGEEYLDADSDNEYRTVLSAPKPKMGNTRPTKRGSTNAMGTSPEMLRRGSSRSSARTDMFPTYTLTENVEANGPIRRPSVRGKMFEKGGKAAGMRKAAIIQSGIVTHSTRPRSPSLPDGRDPPFPIPTRASSRRPPASASAPSDGSHSPSRRGSNRSHYRNNSIRKVRSAAALPRGGRIRRGGSRSPPPLSMSPMDPPTSPSLPPLPSSDLTSPLGRSYRNSSQYRRHRSQLSTTTANTALTANTANTGLTDLQSVTSQTTGVVDAIAQTMIGEWMFKYVRRRKSFGVPESSNREEPSNDRHKRWVWLAPYERAILWSSKQPSSNSILMGGKAGRKLLIQSVLDVKDDNPAPKGATQLFNRSILILTPQRALKFTSTSAERHYLWLTALSFLAHSSQAIPENLVPPNPDPVSFEIPPPVKTRRPGIRDSIRLTKSRHGMSNNFKAAAPPSIPSIPSLPNALSTIGDVMAFQARGSFSTQPSSNQSQHTRDQSRDAAEPPFIPRFSERAMHQGSLHGRKRSNTGGHVPPPLSFRGFSGPAGSSSYHVPSGSVAGTSINTAGSSDAYQQTSSGNTWAGSQRTSEASSRPSNNFFDAIGTVRMEAFISPLAYSQFDDDPDENDEFRASARRRSKEMRRRNSRSRNRDSYNSRWSGSRTGGEEDFFSRDDPFKGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQD1</accession>
    <name>A0ABR3YQD1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Vacuolar cation-chloride cotransporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_005519</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000192">
        <property type="protein sequence ID" value="KAL1890180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018491">
        <property type="entry name" value="SLC12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004842">
        <property type="entry name" value="SLC12A_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11827:SF72">
        <property type="entry name" value="GH08340P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11827">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03522">
        <property type="entry name" value="SLC12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="319"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="396"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="450"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="7">
        <location>
            <begin position="42"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="SLC12A transporter C-terminal" evidence="8">
        <location>
            <begin position="517"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="610"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="915"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1068"/>
            <end position="1158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="612"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="631"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="922"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="938"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1085"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1117"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1144"/>
            <end position="1158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1890180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1239" mass="134913" checksum="464DF7D75FB28B45" modified="2025-10-08" version="1">MRRRRKLLGSSSSHLHHDTGCNIPPASRLPAEKLDATSGVFIPVCLNILSILMFLRFGVIVGQIGLLGIVGLLLIAYSMNFLTALSLSAIASNGEVKGGGAYYLISRSLGPEFGGSLGLLFFVSQVLNTSLNVVGLLDCLRLNFADLLPVGFWVNYALETVVLLFCTAICVSGSSTFTKANNVLLLILLVSVASIPFSAIFKAPFVDAELGVQFTGVSLSTLSSNLLPHFANGHYNGVGTFRELFGILFPATSGIFAGASMSGYLRNPSHSIPKGTLWAMLATLVCYLVVSIAMASSITHESLMSNFNVILLTNISAKLVIAGECVVTLFSALMGLLAAANLLRALARDKLLPGMGPLFSRFTKRDDDPALFLMTYGLAQLALLADLNQIATLISMGYHMTFFIMNLACFLLKIGAAPNFRPGFKFFNWQTAAAGAICSAFTMFFINETYASVAVLLLVLLFALLHYLSPPKRWGDVSQNLLYHQVRKYLLRLQPEHIKFWRPHIILLVNDPRSQAPLIQFCNSLKKGSLYILGHVIVTENFDSCVHEAKVQQMAWTRYISEYSRLKAFVQLTVSPSLTWGVRNLILSAGLGGMKPNIAILGFYRTDKHKPAHGESGQRDAGSRSVWGAADRPKDAKQASETDRPSLFLGPDGGLPTDHIRVEDSMKATEYMTILEDLALRYKINVAIGKGFEGLEIPQKKAGGGHKKYIDLWPIQISADVTSHGRSIHTTNFDTYTLILQLGYILWSVPNWQAAYILRIMVFVEYENEVDQEKARVKALLEKLRIDADIRVFWLASGSLSTYNLVVNGVSSDSKVKQRVHFALRNEPWWHEMQLYRSLQLLEVHSSPRQHVPGNSAAYRRGSLFAASTDSKATVERFRRHSITDLLVKPSVFQLARLGVTVGIHTNHLTGEVLENDDDGMYLGGSSGGGGSGSGTDYSDEEAIEDFTTDDEGGPDDRKSSGSLCQPLLRGPPSSLFQSSASLGRAHSRALQSYGSASSPSCANEPLASRCYGSFSAFTALTPKPRPALPRQKSVVRFTSKLMPETLTNVDAESNMGRSIMFAEAASPNTDSVDAGTLIAGREKQKNKKKPNKKGKKGKKDQRDKKTRASLPSACRSSPTSTSLGLPPIQSPSGPNPKHDPRPLSSTGPSGSAYSTQHMNLSFNDLPSRAQHLILNELMVKHSKPDAAVLLSTLPIPVEGTGASEEASLSYLEDVDVLCSDLPPTLLVLSNHMTVTVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQF9</accession>
    <name>A0ABR3YQF9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acid phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005511</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000192">
        <property type="protein sequence ID" value="KAL1890172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007312">
        <property type="entry name" value="Phosphoesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956:SF15">
        <property type="entry name" value="ACID PHOSPHATASE PHOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956">
        <property type="entry name" value="NON-SPECIFIC PHOSPHOLIPASE C4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04185">
        <property type="entry name" value="Phosphoesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046695902" description="Acid phosphatase" evidence="2">
        <location>
            <begin position="20"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="429" mass="48240" checksum="B56935D0977BCC9E" modified="2025-10-08" version="1">MKSLLFFVLASSSAVHARAVVERSPSEPATTTSSTSCISWETAYTATAAADVAAAAATAKTSSPTSKVKGKAYDRYVSIWFENTDYEKAAGDANFKYFAKKGVTMSNYYAVTHPSQPNYVSVLSGDYFGMQHDDFSRIDGNVSTVLDLLDTKDISWGFYQEDMPFSGYEGYEYKNQANGRNDYVRKHNPGVIFDSVTKSEQRLSQIKNLSMIDTSASQFHKDLAADKLPQWMFITPNMTSDAHDTDITTAGEWLHAFLNPLLDDPKFMHNTLVLVTFDENESYIRHNRIFSLLLGDAVPRELVGTTDTHFYNHYSEIASVEANWDLPTLGRWDVGANVFELVARATGDILRNYTNLDKYYFNLFYTGPMNSLRRRVYPAPNLNLDNSFSGRRILDSIKRTWAGTTLPTYYTDTVEINDGFHPPKGFGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQR1</accession>
    <name>A0ABR3YQR1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Translation initiation factor IF-2, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">IFM1</name>
        <name evidence="14" type="ORF">Cpir12675_005308</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000177">
        <property type="protein sequence ID" value="KAL1890676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01887">
        <property type="entry name" value="IF2_eIF5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03702">
        <property type="entry name" value="IF2_mtIF2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03692">
        <property type="entry name" value="mtIF2_IVc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="entry name" value="Translation initiation factor IF- 2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00100_B">
        <property type="entry name" value="IF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053905">
        <property type="entry name" value="EF-G-like_DII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044145">
        <property type="entry name" value="IF2_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006847">
        <property type="entry name" value="IF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000178">
        <property type="entry name" value="TF_IF2_bacterial-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00487">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381:SF20">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22042">
        <property type="entry name" value="EF-G_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04760">
        <property type="entry name" value="IF2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="Initiation factor IF2/eIF5b, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01176">
        <property type="entry name" value="IF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 14" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Tr-type G" evidence="13">
        <location>
            <begin position="878"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="63"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="327"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="397"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="509"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="560"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1150"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="272"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="64"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="113"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="327"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="420"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="566"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="608"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="654"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="737"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1150"/>
            <end position="1180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1890676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1400" mass="153449" checksum="F297A5CBABFB3FC6" modified="2025-10-08" version="1">MLRGSLAKHHHGATVHFQHLRALQVQSFSKPPRPVQCFRQFSSSGGDEEVLLPYEIEARKRLRSNTATPPSAVSSEPSAHLPKQTSPVPPIPTPKAESTRQNNSRPSVGLPEQINTTIVPQLQPETLPVTPILDTTESITSSPNLESTAIPATNTPTSNASIALKSRIHSKKPAGFTIRKASNDDEFLLPYEIAARKRIKAAEEKAAAEAARAKAIAKAEATINAKAAAEAKGRAEAKALAQEKERGALRQVAEAKVTNEATAAKLMQEITKQKAKDAEEQTMAEARKVEQRAKAAQENARATSLALAEAKARAAAEAKLIADARARAQARAPPTSATEVESRRLSATGTMPLPIRAAFPASTASTSADRQKPLFSIGRKSGDDEFLLPHERAARDRLRKAQIPESSSALAFTPIPDPTSAPQSSGQATSTPTKTLESPSIPPKSSFIIRKSKPEDDFLLPGEMAARGRLLKANAAALSSDIGTPSPKFPSSPNFRAGRSDLDTFLSSKASAQKPDSEQAARLASHLASMSKNASSKLEEGQDPQSQISRFSNLINNLHSQRQKTTESNDIGNSNKSETTSGQGLGSWGLLMRKRREQGKSQSWAQDKNQHQELRENTHHQSNERRRPDARSQSRGLPVNHAQGRSVDLPKNYAYKEAHSVPETPSQHKDDRDNKSGSNLEALGIVVDTSLPPKDSLEAQIQDPRKKGRKGRHNSAEEDEENRKHDSPAKKNKKKRSDMEYDKHGRQLHDEDPDAKAWSAEDERLFEERRRRKDERKAEKEAAKKAALEAEANKVKTIYLPEFISVSALAQALSVKIQEFLDILLEYGFEDMTEDTIMTGETAALIAQEFGLEAEVDDGQARDVRVRPPPEDISALPPRAPVVTIMGHVDHGKTTLLDWLRQSSIAAQEHGGITQHIGAFVVKMKSGKQITFLDTPGHAAFLSMRKRGANATDIIILVVAADDSVKPQTLEALKHAREAQVPIIVAITKCDKPDARIDVVKSDLSRHEIEIEDYGGDVQVVPVSGKTGQGMDLLEENIITLAEMLDMRAELDGMVEGWVLEANIKSVGKAATVLVKRGTLRVGDCVVAGHTWARVRALRDEAGQELKEAGPGTPVEILGWRDLPQAGDRIIQAPDEAKARTAVNYRLEMREREEGQSQLAESERKKKEALVADEAKKAADENGEDAGEEKKGPQIVNFIVRGDVVGSVEAVAATILEIGNHEVQPRILRQAAGNISEFDIEYAAISGSIIISFNNPSLGHIKRLASEQDVRIVEHSVIYTVADDVKTILSKKLDDKITHRVIGEAEVSKVFSINVKRRIYRNIAGCKVRNGIFKRNDLVRIFRKKELLYEGKMSELKHGKRDVMEMRVGTECGVSFEDFQDFEAGDTIQTCEEVRTKRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQR3</accession>
    <name>A0ABR3YQR3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000174">
        <property type="protein sequence ID" value="KAL1890708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011893">
        <property type="entry name" value="Selenoprotein_Rdx-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36417">
        <property type="entry name" value="SELENOPROTEIN DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G05220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36417:SF2">
        <property type="entry name" value="SELENOPROTEIN DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G05220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10262">
        <property type="entry name" value="Rdx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="173" mass="18743" checksum="3A2515FFEC431807" modified="2025-10-08" version="1">MPEPSAFPRITIQFCTQCKWMLRATYFAQELLSTFSTALGEVVLQPGTGGVFIVRIESVSASASAFAPAFASDSGPGSDLISTHTLWDRAVDGGFPETKELKRRVRDVIQPGRDLGHNDRVVKRKARDVKDGVLVDATIETTEPSTRCPAPETQTRAIRAGENDAIQCTSGDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR45</accession>
    <name>A0ABR3YR45_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005222</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000170">
        <property type="protein sequence ID" value="KAL1890826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13917">
        <property type="entry name" value="zf-CCHC_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="163"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="215"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="295" mass="33499" checksum="3086254C90480F2C" modified="2025-10-08" version="1">MYGRGGGKLTSLSSLRHYSYECKTPNQERPYVPRPSRTQQLANPKLQPALQATLNDSIAERKQAAVDSELARREAERERKREREAHEEKLLQLRARSRSPLPKRHKKEGSADGKGRDTRRERSRHSRSSSVETISTNRSVSLVRRTKASRHSEGRSRGRSRSYSRSQSRSRSPPYRDSRTPSQSPSRSSSRGSSRSRSPIYTKKSVAGSRRRRSISPQRRNNNGRTGTYRERRSVSRSASLSLRRRPGREGFEQGLESTSVPSAPLTTPAADASRERSLSPYSKRLALTKAMQQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRL4</accession>
    <name>A0ABR3YRL4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_005152</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000165">
        <property type="protein sequence ID" value="KAL1890995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF48">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G01000)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="341"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="365"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="400"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="433"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="30"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1890995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="491" mass="54367" checksum="F26DFD087C4253A0" modified="2025-10-08" version="1">MNSDSSSIQGRDMDPKREATRNSHDGAPVSIDPKGEARLLLKLDLYLIPTASILYLFCFIDRNARIAGMDEDLKMVDYDFNVILTCFYISYIIFEVPSNILCKHFGPGWYIPSITIAFGLVSVCNAWVSTVSQACGVRFLLGMFEAGMFPGIAYYLSRWYRSSELTFRLGLYVVTAPLAGAFGGLLASAILTMDSFGSFHRWRMLFAIEGIITCVLGLAAFFTMTDRPETATWLTAEEKAIISARLAAERLNNTEVLDKMSKSKLMAGMINPVILITSFVFLLNTITVSGIVFFIPTIVRSLYPDSSTVVIQLRTVPPYVVGAFFTVAISYISWKINRRQILLILSCPLTMVGFAIFLGSTDHQVLYVATFFVCSSTFALGSLTNSTVSANVVTDTARAAAIGFNVMTGSIGGLISTWSYLQSDWPKYTIGNGLNMAVSSLAFIVATLTLIWMKSDNKKRDGRNIDAELAGRSPEELSKLEWRHPAWRWKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRT7</accession>
    <name>A0ABR3YRT7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucoamylase</fullName>
            <ecNumber evidence="9">3.2.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">1,4-alpha-D-glucan glucohydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Glucan 1,4-alpha-glucosidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">gla1</name>
        <name evidence="12" type="ORF">Cpir12675_005347</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Hydrolysis of terminal (1-&gt;4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.3" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000180">
        <property type="protein sequence ID" value="KAL1890565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004339">
        <property type="term" value="F:glucan 1,4-alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002044">
        <property type="entry name" value="CBM20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011613">
        <property type="entry name" value="GH15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000165">
        <property type="entry name" value="Glucoamylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046966">
        <property type="entry name" value="Glucoamylase_active_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008291">
        <property type="entry name" value="Glucoamylase_SBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31616:SF12">
        <property type="entry name" value="GLUCOAMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31616">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00686">
        <property type="entry name" value="CBM_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00723">
        <property type="entry name" value="Glyco_hydro_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001031">
        <property type="entry name" value="Glu-a-glcsd_SBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00736">
        <property type="entry name" value="GLHYDRLASE15"/>
    </dbReference>
    <dbReference type="SMART" id="SM01065">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="Starch-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51166">
        <property type="entry name" value="CBM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00820">
        <property type="entry name" value="GLUCOAMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 9 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046617648" description="Glucoamylase" evidence="10">
        <location>
            <begin position="23"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="domain" description="CBM20" evidence="11">
        <location>
            <begin position="509"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR001031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1890565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="622" mass="66108" checksum="E98D661BDB55017A" modified="2025-10-08" version="1">MVFSKTAVAATAWLMAATSVVANPVSCKRADINSFVTTQRPIALTKLLCNFGSSGCAASGASPGIVVASPSKSDPDYWYTWTRDAGLVLKELIDNVKTNTELLLPEVENYVTSQAHLQTVSNPSGTLALGTGLAEPKFNVNMTQFTGAWGRPQRDGPALRATALIGYYNYLLDNEISTDCKLWQVIQNDLNYVAQYWNNTGFDLWEEVQGSSFFTVGAQYRALVEGSVLAARLGKAHTGYDAVSPQILCYLQTFWSSSKGHIVSNVQTNVGRTGLDANSALISIHLFDPAVGCDDSTFQPCAPKQLITTKKLIDSFRTVYSINSGKSAGTAIAIGRYAEDVYYNGNPWYLCTLAVAEQLYDSVIAWKAAGSITVTSTSLPFFTDLLPSLTAGTYASDSSTFQSIITAVTDYADGFVEVVKTYTPSDGSLAEQFDKSNGTPLSAHDLTWSYAAFLSATERRAGTVPPGWIGAASVSVPTTCTPTTVTGTYVAASNCASSGAGDGNSGEPDDGSNDAKLIFNELAVTYFGENIKVVGNTTDFGAWDPASGVLLSADAYTESNPLWSLTTSIARGTGLEFKFIRVGSDGAITWESGDSKVLSASSEANTVTVSATWNSDYSVNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRU7</accession>
    <name>A0ABR3YRU7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_005317</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000178">
        <property type="protein sequence ID" value="KAL1890593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF10">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="12"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="78"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="156"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="592"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="198"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1890593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="783" mass="84901" checksum="36BA1C304A43BC6F" modified="2025-10-08" version="1">MTDQPRIKGPRACVTCAKAKARCIPGLPGTTRCQRCNRLDKICENQEPAPPRPKKTPKLTRVSELERRLNDITAKLQATQGSPAVGSSVASSSGVAGSHSPAPPSRSPSLTAEIRMASIEQHDELPNKRRRNTNLGESIKADYRFNHIFPHQDSVLPSAETSSLSPNSGGAIPRSPSMGSPVASEPAPSLMSHPSMFTSTSASATTTTATSASTPVPGPSRVWPICTSPEAADLLAIYRESREPLFPFVIVPKTMDATELASTRPLLFRAVMMVSLFYDGSHQTAAMQELLDTLIAASFLGKPQRNLDLLQALELLICWVQFDLNGFQTTNLIFLIRGITASMAPKNAINSVPDSHMLEHLRAFVGVYYINTFVFTTNKRLDVFMDTSPIDNWCSIIEMHNELPSDELLVHLVRIQRLAQIISITVSSSNNNRLATGVPPAPLSMAVHGLQQQLQDFKAGLPLHLRSSSAINTHISIAEILLYEIALSDATSSQLLASQRIQLLWNCAAAIKSYIMHRFPADRQTPLDPTKQPTSICLSCYDFAFAILTSLKLLLLRFPDWDRVQVSQHLELGPAIDMQVREMEDFIESRTMRHRKQHAEEPHQTNAGSGSNSGLGWGSSELNASSWAAAALSSVKTSAPPMPDPLKRLVITLKNLRVMLDKEMELIVQETRTLGISGVGPAAAAAVDPAFNSSAPEIGGGPLLENLDAYQQQSQGQPQAPNVGASGIPQMMLSQNAVISQQQAAAPPLIPTDISHLHGLDPIFSDIGSSLWGEFAGEGMWAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRW0</accession>
    <name>A0ABR3YRW0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Autophagy-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ATG8</name>
        <name evidence="10" type="ORF">Cpir12675_005107</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Autophagosome membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Vacuole membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the ATG8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000163">
        <property type="protein sequence ID" value="KAL1891099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16128">
        <property type="entry name" value="Ubl_ATG8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004241">
        <property type="entry name" value="Atg8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10969">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02991">
        <property type="entry name" value="ATG8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0072">Autophagy</keyword>
    <keyword evidence="8" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="121" mass="14117" checksum="DC81F00BF3FF4108" modified="2025-10-08" version="1">MRSKFKDEHKFDKRKAEAERIRQKYSDRIPVICEKVEKSDIATIDKKKYLVPADLTVGQFVYVIRKRIKLSPEKAIFIFVDETLPPTAALMSSIYEEHKDEDGFLYITYSGENTFGNFETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS66</accession>
    <name>A0ABR3YS66_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Extracellular mutant protein 11 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005092</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000162">
        <property type="protein sequence ID" value="KAL1891123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029178">
        <property type="entry name" value="Ecm11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053029">
        <property type="entry name" value="RNA_pol_I-specific_init_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28244:SF3">
        <property type="entry name" value="EXTRACELLULAR MUTANT PROTEIN 11 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28244">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15463">
        <property type="entry name" value="ECM11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Extracellular mutant protein 11 C-terminal" evidence="2">
        <location>
            <begin position="391"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="526" mass="58347" checksum="84C7706B0A326210" modified="2025-10-08" version="1">MMEHNSLGQSLLNYAKASSDAGTARSNSGLESALDALTNGKNSSANTNHGTSTQQNGLQNYEARNSPDPRRSETPNRLSQRQSLASAARIPLAVNTRMDNGYAPVSTPRRNRVESPRSVRSVDHHPAGIWSPSVLSESDFNPPSTVDTNRYQHQHIGFKLKYDARDTKRETGKDMGGEDVFVGIGMDNSRRWGRRDSRPPAFSISDGKVSVTGIQAPMRTTADYRGSPERAPSQSAARGADSKPRPAYPNNLFGSDSDDGDVEDENAGGEPENFRKNAIQHPVAPRPMQPHRQTALDLANDDLDSLLDEDEMDDDDVFGSKSQASDQPTPKATRKTAVKMASKSHLPQQQAQEAVHAPPLTSRPPLSSILSKMARATSESNFQKRRRPSYDYDDSVLQKMAYSELKSQPFDYDPAVAPALQTTVGHGETLPAQLLHYKTRTDADQRDFFSRMTVTDWERSGDWFLDQFGDLVQQVIQARKDRRAIVGQFESEVASREEQVRTKHDSVERKMNKMKHNGLKVVGDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTR2</accession>
    <name>A0ABR3YTR2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004973</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000155">
        <property type="protein sequence ID" value="KAL1891359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039719">
        <property type="entry name" value="FBXO28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13252">
        <property type="entry name" value="F-BOX ONLY PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13252:SF9">
        <property type="entry name" value="F-BOX ONLY PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="2"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="596" mass="66488" checksum="76F8A1144FB54756" modified="2025-10-08" version="1">MTLGLVDLPCELKLLVLAYLDSRTITRLMTVSKDFRKLCLDTNTWRLRAFEDSTFLSNALRRVSVAPCATPRAQLLTNWDYTDPQEPVSWYREYVERYGPVQINWFQQPQISESGISDTIESRGLALYTPGKLGRDSPSDDLLAVSPLDDGTVCIWDVAGRAQRKRGSIVAISKTPVLHTYPGSNFASRSQRIDSSVTESVAIDHASNRAFFAVQSRLVEVDLSRLESISYQTFEWSIMALSKCSPGLPLTVGTSLGIFLHDFRDSRRRHLISPDVSDRVDNFNVFSGLFSQNPLPPYASLSQPTPLSILHLPTYDESTVSHDIYVAGRFPSILHYDRRTFPSIVDSIHSGASLSCLAWTPHVFSTSNHGPSRRQGLLPIDVISATQPANGRTLIAGGEYNTKGSLELYSLSRNPDHPGRCARPTPENSLANRQTSASSKIMSITTHGGRIVVSDASGFIRWFERDGFSEVRRHHIGPSECLDTSPGSLYAGMPATGEMARKILSTQSVSRWHQIDSNEERPENVIDTYDDGIVFWTGDKLGMLRFARKPVVWSADFEAAVDVSPEERGERAYRQRMREVFDTDNMLRNLTSSTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU41</accession>
    <name>A0ABR3YU41_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004784</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000144">
        <property type="protein sequence ID" value="KAL1891895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="353" mass="39941" checksum="04764E131611EB3C" modified="2025-10-08" version="1">MNRKDLKTPDFYGTVSAVGNPWGPPPSRSPLYPDNNNNNATAVNNTIANKAYPFDPTLWQNNAPASGPQNVYSVPVGTPSHMTKTIEGVYPTFPAYATPSPATAAPFTPTPVQFAFQQPPGQWEQDRYSPTDSVDDILTSPLSDYALDNGSGANHSAKNNGPPKRSQRRPSNRDEFDGPHQFLQRPPADYIARQERELPHLPTNLLVQEQDNVLNQVNDRLSQCAYDFVAKYQFPIPLTNDMRPVERPQDREWTEWVYLLKRLATKRRIPARVLYNGQIKQFVTVLENSLEMRHASKHQSRPLKDDRNILQLISAGIQVAKILKDASAMDYLDRLYVSTEKQIQERASARFRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUF2</accession>
    <name>A0ABR3YUF2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VPS9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004942</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000153">
        <property type="protein sequence ID" value="KAL1891465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.80">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003123">
        <property type="entry name" value="VPS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045046">
        <property type="entry name" value="Vps9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037191">
        <property type="entry name" value="VPS9_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23101:SF97">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G10890)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23101">
        <property type="entry name" value="RAB GDP/GTP EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02204">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00167">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109993">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51205">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VPS9" evidence="2">
        <location>
            <begin position="184"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="376"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="547"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="602"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="386"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="610"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="623"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="665"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="717" mass="76899" checksum="011ABC17551DA52C" modified="2025-10-08" version="1">MDQFSSVNTPRPQGTPASEPFPLLSDVPRQSIDLGEIPIEIVTLSDSFVESLTAKVHPTPPSIDRLHVLFQEFYDLASSHISTHIATLATQQIRESSSAPTSTVPSLSRSFLGRRAPASAAPSTKRNAPEDSEQQMLSAEEMAAKQQARKAFEAKKMRLEEAVERRLCEGIYDRIYRHRSTQDQASDDRLRSRTAALALVGINPSDLGIALGEIAEDTPEAKIAHEEKIKAWLEDARKSLVRMHESHYPLGKLNHLRSAHRAIVETLARFHPSSSSADEILPMLIYTLITMPPEDLNVTSDMHFIQNFRWTQKLSGEAAYCLTNLEAAIGFLETVDLSTLRADERPSGPIKVPGSSSLTKSATFPPAYTSDFAASMEGTETDTAPSETSKSRTNSRSTSPSAATTSTTTTTMSGTILAGLSRPSKPRTLSELANAPAANAIGVASDILTTADQGLKNISTSLGDSYKFVLGKLREPNATGRSLVVPTTLEEARRLISTPPPEEETFSYGNSTDGHDVASPNAPRDTLHRPQPLECKMFDLMGGRKAVNRNAGSGAPSRNAAVKDSIPSSSGSNTAVLDSVLNLGSSLNPMARLSSISSFRGFGRSASGSQNPSSTIAPTSHPSASSGNANVSNVSAPLGSGGSDADVAPDEGGHPVSAFPGPTHILPPPELPRIAPPKKRFMELQNPGDIRVSEVIDLLRDYRRLAKALEERNAFIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUS2</accession>
    <name>A0ABR3YUS2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004685</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000138">
        <property type="protein sequence ID" value="KAL1892135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF150">
        <property type="entry name" value="OXIDOREDUCTASE TDA3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="2">
        <location>
            <begin position="8"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="439" mass="47340" checksum="B4B1C5649E14AA5D" modified="2025-10-08" version="1">MSTQKKNIVIVGGGIIGCTTAYFLTRHAKYDPELHSITILEASAIAAGSSGRAGGLLAEWAYPECITQLSFDLHARLAQTHAGVQKWGYRSVSCGTVRARVTPEMAALQEAQDSGNASTTPAPITLPAEEAAETGGVAWNKLPKQDDRVRPKLAPENFPADLDYVDLETVTWWDAMDGKTAQVHPLHFTTAMAELATAAGVTILVQTQATKLVKNEANDRVTAVEYRERNSDKTKMLADVTDVVVATGPWTKSLLPAAQITSVRAHSVVYEATVAPYAVFTGITLPAKWVPAHRRAAGQRRKHQRTVDPEVYARPFGEVYACGETDSAIPLPDFADQVQVDSGQCDDITAYIGLISPPLRRAPIKIKQACYLPQHTPYNGETNPLVGPTKTGGLYVAAGHTCWGIQNGPATGCVMAEYILDGKVTCADVTQLDPRRYSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUS7</accession>
    <name>A0ABR3YUS7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Checkpoint protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hus1</name>
        <name evidence="6" type="ORF">Cpir12675_004681</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the HUS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000138">
        <property type="protein sequence ID" value="KAL1892131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016580">
        <property type="entry name" value="HUS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007150">
        <property type="entry name" value="HUS1/Mec3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12900:SF0">
        <property type="entry name" value="CHECKPOINT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12900">
        <property type="entry name" value="MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04005">
        <property type="entry name" value="Hus1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011312">
        <property type="entry name" value="Cell_cycle_HUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="204"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="207"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="220"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR011312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1892131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="358" mass="37946" checksum="1118CD30EB80B4BB" modified="2025-10-08" version="1">MRFKTEIQLTAAVGSLEKIAWVRLDDDSVRITVIPDIGSQVWASLSADLIFDNYSIQSAEENNTINLELPMQPLQRALKSASAANAISTTLRLTKKGGLPVLSMTITAAGTVSGGGGGGGAPTRPGGADEFGFGDDDAAAMMEMSLRREREKIITQDIPVRVLHPTTVETIMQPKVREPDVHIQLPPLLQLKAMSDRFTRLASGTVSGAGGTGSGGGGPASTLSGGATSGTSNMRAPKLALSANMHGGLRLRTATDGSAVESEWRGLVNPALDPAQLAMPLAEHPSTHYREGGPDMWATVHVDGRDWSKVLSVGRLDGRVIACFSHDHALILYVYVTHVDEPGSDDSVITYYVQSYSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVJ8</accession>
    <name>A0ABR3YVJ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004999</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000156">
        <property type="protein sequence ID" value="KAL1891349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="90" mass="10210" checksum="1A168E009F770DEE" modified="2025-10-08" version="1">MEYGLNSPGMETSRRPSQYSTTDGMTLEAEKGPQLIHQDWNPHSLSDPFNRPEIPPLRAIKLSPEKEAEHAAILAAAKERARELDKSRWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVJ9</accession>
    <name>A0ABR3YVJ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_004770</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000143">
        <property type="protein sequence ID" value="KAL1891911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF55">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="6">
        <location>
            <begin position="606"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="121"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="175"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="270"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="364"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="448"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="542"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="299"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="333"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="364"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="492"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1891911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="845" mass="92653" checksum="2C15FF58CFE0CCCE" modified="2025-10-08" version="1">MSAVTQVLKTLLLSTLKLIFSRIPSLLSNMDSIQPRQMGIGSLAFGIFFLCTLICYAPVPVRILVYLGTISVIFYLDKCLSQAKYTNSQSQDESWELSGKTKPTISLDIDQGSLHSHAKITPKPQHQQCCQHDGGVGDKYQPKEPHVQRDQPGGSIPPSLSSKVSQNAFESLADASASVECQSPDVSDPASARGPIEPYADPSAATSQPKASLVHFKEKNEGRAGNRARIKIANKAKVKVETAVSSDAYHSLNSGIPGDATLENGDVDAADSLESKKPSPNNATAVGPELTGAQNSDKVLVDKQPVDPRVPETLGATGGSNTVQPDKGESNGEVINNLDSGPNASADILGGVEGGIKEFGKDIEENSGDVERDGENAMKNKQHEHTNVEGNTRKERKRSQDGGGADEDGGTTVATMLGSTKADAGANMASAEITATGETAIANDDAKATGSTACDGQAGQEAISKNSPAENLDVKPSGTQSPEATKSDGDENANNSSKLRGEQSYQTLGDSESFAAAKNAIKWDMPSNFPWVSFQTQHLLKRHKSQQSRKDRHCKLHKSHKHHKKQSLRHKKSFTEGETIVDANGGRVALCENGDILKEGPKVRLNEEIAMDFIAKHCPSITVPKVLRSEYGKYGRIYMTKVPGVVLSDVWLQFNEETKLRVCRDIWALVEEMRNVKRPEGHFPERKYVTMDGGYTFDPLLGVHDDPTPPLFNDQIFRERIEQRYLNAHQWESMRRSRCKKSPSLIPTSQQKVTREILHLPHCEKEVLTHGDLAPRNILVDPDTALITAILDWESAGWYPDYWEWAKILNPWNDPDWKCHMKATSPFKDQNWDVSGIMFARRLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVK2</accession>
    <name>A0ABR3YVK2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Ubiquitin-related modifier 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">URM1</name>
        <name evidence="7" type="ORF">Cpir12675_004797</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 6">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="5">C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of UBA4, then thiocarboxylated (-COSH) via the rhodanese domain of UBA4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the URM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000145">
        <property type="protein sequence ID" value="KAL1891793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01764">
        <property type="entry name" value="Ubl_Urm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03048">
        <property type="entry name" value="Urm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015221">
        <property type="entry name" value="Urm1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14986">
        <property type="entry name" value="RURM1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09138">
        <property type="entry name" value="Urm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037379">
        <property type="entry name" value="Ubiquitin-related_modifier_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="MoaD/ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="modified residue" description="1-thioglycine" evidence="5">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)" evidence="5">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1891793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="116" mass="12426" checksum="9E0F79F5F8CD5A2A" modified="2025-10-08" version="1">MSAITETMGPRVVTIKVELAGGLDILFDGKPQLKVAIAASSVNDDGAPSIRMSELITHLGEEVMTDSRKDLFVLDGSIRPGIMVLINEVDWELEGEEECVLVSGDEVLFVSTLHGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW71</accession>
    <name>A0ABR3YW71_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004687</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000138">
        <property type="protein sequence ID" value="KAL1892137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="378"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="394"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="526" mass="58407" checksum="DF9FDECAD18A93D6" modified="2025-10-08" version="1">MSASQADSASPKSSPPSHHCSSTPTTPTPTTATTTTTTVTTPGAATPKPALRPRGKRPESRADSLGSLVIGDSASDQGRHGSSGISIETSSLYHETPEQVRERELRTKTLGYFLAKVALTLDDGIKIFHFADKRNWGPDEFEQLRALERCLDEARRDFQELPTLLDGTSYYTNDRTRASLAEIAILHDRLEDHIEVFRMWIRHGGPINPMWINDTRVIQQDLHNSQCRAARRIFDTKHESTSRCLGAFLVYRQQRAWVGRQDPHDPAYRRHCLNEIAACNTVGRFERFGDCDIAFVCNFCDGYVVWDDLESMPSTLKANDMAVATAVHQGGNSGTDSDSELPQRIHDESNSSRTSNASPPPPSHTGSQGSHSHDNDTNHGYTYTTHGYSYNPQSTSKTPSSKPTNSPDSNTPLELPYPEWQSTGFSATEHQQKNIVFAPVAIASHAPPIGMEWRASHLCRFCDETFDSEQKIAQGNDDIEPFATEEGPGFESVKSFEEHLLWNHTPYTMEMPAVGLPRLTESCAVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX42</accession>
    <name>A0ABR3YX42_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Succinate dehydrogenase assembly factor 2, mitochondrial</fullName>
            <shortName evidence="3">SDH assembly factor 2</shortName>
            <shortName evidence="3">SDHAF2</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">emi5</name>
        <name evidence="5" type="ORF">Cpir12675_004324</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Interacts with the flavoprotein subunit within the SDH catalytic dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SDHAF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000119">
        <property type="protein sequence ID" value="KAL1892956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.250">
        <property type="entry name" value="Flavinator of succinate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03057">
        <property type="entry name" value="SDHAF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005631">
        <property type="entry name" value="SDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036714">
        <property type="entry name" value="SDH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028882">
        <property type="entry name" value="SDHAF2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12469">
        <property type="entry name" value="PROTEIN EMI5 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12469:SF2">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03937">
        <property type="entry name" value="Sdh5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109910">
        <property type="entry name" value="YgfY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1 3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="187"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1892956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="212" mass="24043" checksum="DF9B939763F8384A" modified="2025-10-08" version="1">MANLIYSTSRRIFAHRSLIATARAFVPSRSLATTAALRADETAHRELDVGELEGITLKIEPLQRSGESDDTMRARLRYQSRKRGILESDLLLSTFAAAYLPTMTRAQLEAYDKFMDENDWDIYYWATQPDAPPVDDASLKDEWKREPGTGEWAQTVGTFRPAYRPVPSRWKESEVLLLLREHVKSRSATDGQAGEGMAFMPTLEETKTGRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX61</accession>
    <name>A0ABR3YX61_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glycerol channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">FPS1_2</name>
        <name evidence="10" type="ORF">Cpir12675_004523</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000130">
        <property type="protein sequence ID" value="KAL1892440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00333">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050363">
        <property type="entry name" value="MIP/Aquaporin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00861">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829">
        <property type="entry name" value="AQUAPORIN OR AQUAGLYCEROPORIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829:SF9">
        <property type="entry name" value="AQUAPORIN-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="197"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="220"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="328"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="14"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="381"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1892440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="401" mass="42681" checksum="1258985D8855EC08" modified="2025-10-08" version="1">MAPPPTSPKFIPDAQHEKLSPADSQDTRIQHKPSNTDPIYNEPNLAGNASWPHIRHRYQDCFAEFLGTLVIVLFGDSVVAQSVLSDSAAGGFISINFGWALAVAFGIFASGKSGAHLNPAVTVALAVFRGFSWRKVPGYIASQMLGGFLGAFIMYANYVSAIDNFEGRGVRTVGGETSTAGLFCTYPQPFLNKAGQMFSEALASAVLMAGILAVTDRGNIGGVVALPMAVGLLVFAIGLCFGWETGYAINMARDLMPRLASYMLGYGSGVWSAGNYYFWVPVVSPFLGTLLGAFIYDLLIFDGESPVNTPYMGMAGLFSREPKKAKADIEAAPTQLPRPAPGKISPPVLPNKVPSSPGSSKDEGTLGHISDQPSPDMEVQTPETMWSGATFSAHPPHAHLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXC3</accession>
    <name>A0ABR3YXC3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_004561</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000132">
        <property type="protein sequence ID" value="KAL1892408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024604">
        <property type="entry name" value="GSG2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24419">
        <property type="entry name" value="INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24419:SF18">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE HASPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12330">
        <property type="entry name" value="Haspin_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01331">
        <property type="entry name" value="DUF3635"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="159"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="570"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="583"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1892408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="594" mass="66847" checksum="C1398259562D9B1D" modified="2025-10-08" version="1">MPKATAKTGKGRRTKTAVEVLPNHLGLFPESVADITGLVAAVSIGDVDGDMNAECVPSPPQKKAPNQARRRQTKQKKADTICYADNPDKYSVDPLLPQVSSITNISTVVSEKTTGTAKSLEGDLAKTDPIHSQAEISLISTIDDTELRVIGWADVCLENDRIEKIAEASYAEVYRVTNEEGVSIIKVIRLESPIKAQTTQQKRSGLVDEEPHAQGDLIGELRISEWLADIPGFVVYKERYVVKGKAPKALLDTHQAFQRKCKRQDPGRLQFYPSPSRYLDDTKFLVIELGDAGTALEDFKLTTQEQLWDVFFLVAIALARAEELVLFEVSYYFSLFSQGVCANLQQHRDLHEGNLCLRQVCKPRTRDDSTQSQTQFGYSGLDITILDYGLSRAEDPECGEEEEVTVAYDLEKDLSLFTSTHADQCKVYRQMRSFLLKGEREWLAPERHNIPYESGVEGPICWEDYAPYSNVLWLAYIYEYMERHFRGPKKELASFTRSTKELWQYLDPEAPKEAPCFGSAEDVVRFGVEAGWILPEQLMGTDGSTLVENEREELEDKDVLETVEKLAQLGLEGQSTENPAVKKSQRQRRIKGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYQ2</accession>
    <name>A0ABR3YYQ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">COP9 signalosome (CSN) subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CSN12</name>
        <name evidence="3" type="ORF">Cpir12675_004229</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CSN12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000115">
        <property type="protein sequence ID" value="KAL1893210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045114">
        <property type="entry name" value="Csn12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12732:SF0">
        <property type="entry name" value="PCI DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12732">
        <property type="entry name" value="UNCHARACTERIZED PROTEASOME COMPONENT REGION PCI-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="2">
        <location>
            <begin position="252"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="455" mass="51544" checksum="03DC98826B6EBA93" modified="2025-10-08" version="1">METAIREFSQSYAQNNGFRLAESFSPFSNTEDHNNLRRIFNSTSSSFVKRDVKNALVKYKGLTKLSTDELNGWVEVFCAYWKAAGHIVATDDGIASDRTSSWKSAYDAWREVTSQLIRGYTNHSFEHWTFPCLYTTGKYLRIFAIRADSERSSQAASSDAIQLGDDFDPELETNQTLRDCEQQLKRIFTLCLSDRAPIEESRKWALYYIVNLLFKTYFKLNSASLSRTILKALSAYQGDMPPLSSFPAAQRVTFKYYEGVLSFLEENYLDAEKHLTEAWLECHVDAMNNKEQILTYLIPCHLLTTHTLPGEALLAPFPTLKRLFQPLSQCIKRGNLAGFDAALAQGEDEFIRRRIYLTLERGRDIVLRNLLRKVFLANGFEEPKTAGDAPVRRTRVPVAQFTAAVSLASGRSVETDEVECLLANMIYKNLMKGYIAREHGIVVLSKTGAFPGTGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYU0</accession>
    <name>A0ABR3YYU0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Putative phospholipase</fullName>
            <ecNumber evidence="4">3.1.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_004300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + acetate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17777"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30909"/>
            <dbReference type="ChEBI" id="CHEBI:36707"/>
            <dbReference type="EC" id="3.1.1.47"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the serine esterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.47" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000118">
        <property type="protein sequence ID" value="KAL1893066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016715">
        <property type="entry name" value="PAF_acetylhydro_eukaryote"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272:SF7">
        <property type="entry name" value="PHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272">
        <property type="entry name" value="PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03403">
        <property type="entry name" value="PAF-AH_p_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018169">
        <property type="entry name" value="PAF_acetylhydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3 4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="450"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="524"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="450"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="533"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR018169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1893066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="567" mass="62270" checksum="B5755F97CB2D556F" modified="2025-10-08" version="1">MIPSFPHYTGPYQVGSIDIEIPVSELESPVSIPSDASDIHTVLVRVFYPATPESHDRNVDWLPSPQRQSLSAYARFVGLGPAAASIVSYIPRHTHYTKIPAHKNAATFASPLASDGRWPTAIFSHGLAGCRNSYSSIAGSLASHGVIVFCPEHRDGSAILTMVRNPSARARRFPNWWGTAEMRLYLDIGHEVTAETFKARDRQLRIRLWELGLVHSLIIAIDRGQKLGNLKTSARSLGQFADKMDVHRPGKMVFMGHSFGAASVVQFIKSVYYANSPALKGLADPLFVPHRDSNLCAQITHENVVILLDMWCLPLFDPSTTALLELPLPAYDNVRGAPGGRAILAVDSEQFVKWSEHFHATARIVSKRPGQRVVSQEDFVNQATGAKMDPARFFWVHGSAHMNQSDFCVLFPWLTKKIFKAGHPEQVLRLNLRAQLQVLRENGVVVAETSAKDRVDDGREDANNCSSSHGSARASADGEPELGHENSCVRLSYDNTIFNMPDTIKAWGRVDIFEMGAESANFGWKTDSANPMSNSDSDQSTSATASTNGGQGNLEISQETLAQQISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ15</accession>
    <name>A0ABR3YZ15_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004034</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000106">
        <property type="protein sequence ID" value="KAL1893646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="326" mass="35141" checksum="0F1478254340FAF4" modified="2025-10-08" version="1">MDTLATATSTDTSQGPGPTSESSTVASVPPMITPWRRPDSVECHYTFNVDHLTQNGIVSAWMDLHIDPDATTFSCYPPGMFAAGNSGTFSPAICPMSWSTVGYIEADDDVNGATTLQCCSSGFALDAGKNCVRTYSRVTATPATYIEAESTYSYMTESVTVLSQATVAHHHIVAEFDQGDKEALGILNNNKFLSGHPPDLGLEVKLGITFGALFFVCLVSLAVCMFTRWRKKKDNEDSERGSQGRNINTCNRNILCRSSYRSNETSSTVDYSHAQPESGSTPVPLLHFGIANAPLAKMETVDSSTSDAALQQEKNRAVPHNNLVGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ30</accession>
    <name>A0ABR3YZ30_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004038</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000106">
        <property type="protein sequence ID" value="KAL1893650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058925">
        <property type="entry name" value="zf-C2H2_AcuF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35391">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35391:SF3">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04300)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26082">
        <property type="entry name" value="zf-C2H2_AcuF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="800"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="865"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="556"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="430"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="456"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="472"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="560"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="598"/>
            <end position="607"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1114" mass="123535" checksum="D813D47AA01D1D50" modified="2025-10-08" version="1">MASTNLATTQNFTDSIASKANEHMLPEAEYIDPKLLSPDFSLTTTTPNSHIDPATASPGGSFYQPSMSNMPGDDLDDLNSLNFDDHHCCDEPFFVKQQSTLNLLPALAPDASTTSHDAIRGRSAVMSTGLLEAHAIHIPPHIPSNLAHQTGSEIQDTVLSPSSPASQNPHVTIELWDNNNCVSVSENGSVPISRTRDQSPARSFASDAATYQDDMSAVYTPSQTGQESLQPQSRLPAVSSHRSGGVAPPDRTDEISESINDQHKNAQVRERNESVSQWLQQDIPAFLPEETASSVLIDQRGIDAANDSIPLGRKTENKYVSGETYIDPKGGHLDPIDIKIIRDRPRWEDGPKFHAIDYNRTAPESSKEAMERYRLLLDNDSVLSFAATVGTTNQHENPFDFENAEVLNGNLFKKFNLRRRAKSVNHVLQGFQNRMLNPNTTGNSKRSLNSNDDEGSGSSSGTSTENEARSRSPLHVRRSSSQKKTTNIGTIFANVGGSAAVIGSTHTRHGSINGPSAPVNKNSLNEFIKRRGYSISGESRSSESLSLVGLLRKNGGPPVATLGTQTPLPPTQTATSAQPPTSIPAPNTTPEINHGSDDSSDDDIIDDDEENSLVDDFAAIVTPSIDGFRDQFKMLNPDILPENEFMIDRISHQQEQRYKALVNNRIAHTKLGNRCRNGENCINQGKSITSVVSKSKPAKSGGALAEDEMHTNAVMIARHKFPKGIPKPMTDRVPAVFECHLCFQKKPFHKPSDWTKHVQEDISPFTCTWRECKEPKIFKRKADWVRHENEGHRHLEWWTCNVDDCSHTCYRRDNFLQHLVREHKYSEPQYKTKTQINKHGAKDPTVRCAIACHHETEKLPESEPCRFCNKTFPTWKKLTVHMAKHMEQISLPIINLAAQRDVDENTVISPVHDLPPQSFPTTPNAEKIANLLEPKPPIINTLTSRQHQEQQQQQQYMQMPDQIHLQRFEYVPVGSLHPFGLPHTSPLPQNGFPQVPIMENNLGLPSQTLPRYNKSGGYIPQQGHSSPAQPMTHNMPPVVSPEPLVFDTGFTPGGFSAQQRQQQSMEQFGDPTNSLGLYMSTASNAIEFSLGTNGMVNEQYGHNMPMQNNNASFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZL7</accession>
    <name>A0ABR3YZL7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCZ1/INTU/HSP4 first Longin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_004160</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCZ1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000112">
        <property type="protein sequence ID" value="KAL1893377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013176">
        <property type="entry name" value="Ccz1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043987">
        <property type="entry name" value="CCZ1/INTU/HSP4_longin_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13056">
        <property type="entry name" value="VACUOLAR FUSION PROTEIN CCZ1 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13056:SF0">
        <property type="entry name" value="VACUOLAR FUSION PROTEIN CCZ1 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19031">
        <property type="entry name" value="Intu_longin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCZ1/INTU/HSP4 first Longin" evidence="3">
        <location>
            <begin position="10"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="325"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="419"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="766"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="339"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="770"/>
            <end position="782"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="918" mass="99061" checksum="C310B967340C9D86" modified="2025-10-08" version="1">MTTITAQLGFLAIYNPSLGTSDETLDEQIVYYASRKLLSKKRRRNRRRGGLADVTSPEERNERLRQIGLAQGMVEFGRSFAGNQAVDFVDTEGSRVIMHELEAGWWILASIDLTRLPLPPKLATGKQTAPLQEKYEYSTRDLKPANLLLCDLLRAHSIFLLHHAPSLSLFLERRRKSHFLTVLGRYWDLFLSTWDVMLHGNPLRSLVGGISLAASGELGVGVGEEESGSGERDVLEGLPWRMDGLVDLVVSKFGTVEDEPENDITISSHTTTAVRPSWIGSGKEPSASDGAIFLGVGALSRNSLREIVHWAEDLYTWGENTYGVVNPSSAKPSRKSRRGTFSNTSASLSPLDREQEKHQRRNSMASGHPDDTSRRKLRDIPPVPIQEPTHEEAPLPSATRLLSQSIPQSLMKLSQLSIFSSDAPPDGSNAPAKPSQPKEPSSDKANLLSVEQSQPIVAEGCSNTSIPPDTVSNIPKRQDLDTKALQAPIVEGPGDGAMDKFKNYLKLGYGTYWSLGTQEASKSVEKPKPQSSSGIVPIIDPRKANDPTNHFLIGLRREADPLLTEDDISDASDTTDSLLSSATILRRTVYVTPRNTNSTENNNKKHAKLRVVVYVNRPFIFVLLFDPSIATTSLSSEPLYNTLHTQLSAVRNALIKSTAHPIPRPVPGIFDMIYDPSSLALLCSVPNIPVPISGPPAPAGVIGGVEPRKDPWSRADAVSTHLHMLNILTATSRQPNAIERSAKTSRGWWIVWARVLKELDESAAMPATEPVSSGLETITESPVASAHDVSSLAKTSDDGASGHVSSRTCTPPPIHPFIKHTCAVHKEVFLVRRASDHASWRSFSASLMETVEGASASSSIASAGGADASGDSDGPLSIGRAAGAGFIAAAGEGGVAGGLARGIGVDTRKYIEGLAGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZR1</accession>
    <name>A0ABR3YZR1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein LOT5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_004097</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000109">
        <property type="protein sequence ID" value="KAL1893444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039924">
        <property type="entry name" value="ICln/Lot5/Saf5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21399">
        <property type="entry name" value="CHLORIDE CONDUCTANCE REGULATORY PROTEIN ICLN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21399:SF0">
        <property type="entry name" value="METHYLOSOME SUBUNIT PICLN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03517">
        <property type="entry name" value="Voldacs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="248"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1893444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="301" mass="32603" checksum="07A72057EDA66DF4" modified="2025-10-08" version="1">MLLTTIRTPPKVDDYVTLEDYQSQTPASFHDGKPVLHLNLRNAKAWFPIESAGKLPVFPMAESHSRPTGPESKSLGESISERIEQKIEVFVTSQTLILYNPVAETGVSIPYPLIAIHAAASLGTGEDRVKTVWMQIQLNESGSDDEDFDDVELNIVPDQTTEEVPATVADKLYSAIANCSDLHPDPAVEGDDGDDEAYPEIFFEGSVEHEALEGFSGVLRGNSNGSLPPPMPGSSGWITAENVHEFFDSDGNWIGGQEESASGELGEGAGRVRSHEEASGNTNGHLESKDDDPDSKRPRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0H8</accession>
    <name>A0ABR3Z0H8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Quinate dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">QA3</name>
        <name evidence="2" type="ORF">Cpir12675_003997</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.24" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000104">
        <property type="protein sequence ID" value="KAL1893697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030266">
        <property type="term" value="F:quinate 3-dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01065">
        <property type="entry name" value="NAD_bind_Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013708">
        <property type="entry name" value="Shikimate_DH-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022893">
        <property type="entry name" value="Shikimate_DH_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21089:SF1">
        <property type="entry name" value="BIFUNCTIONAL 3-DEHYDROQUINATE DEHYDRATASE_SHIKIMATE DEHYDROGENASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21089">
        <property type="entry name" value="SHIKIMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08501">
        <property type="entry name" value="Shikimate_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Shikimate dehydrogenase substrate binding N-terminal" evidence="1">
        <location>
            <begin position="37"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="330" mass="36513" checksum="4FA60FE5B3FE5364" modified="2025-10-08" version="1">MAALALTRHALPSFPIVEEKPQSPVPEVERVEKHSYLFGKKIANSYSPFLHGTIYRGLGLNWEQFRLDSTDIAQFLELAKHPNFYGAAVTMPNKVAIMPYLDEMTPECRDVGACNTLFIRYRPDGSRVYCGANTDTIGIRESFYQNVPNPDAVFHDRPALVIGGGGAARSAVYALRKWMRATDIYLVNRDASEVQAVIDECSERGYGAGLVHVRTVAEAKAVAAPGAIVACIPDFPPVTDEEKEARAVACTLLNKDTKGAMLEMCYNPNPYTELGGLAEEAGWQVILGTEAMIYQGLEQDRYWTGKEVKDLPVDTVKKAMMEKLTTVKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z124</accession>
    <name>A0ABR3Z124_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ysc84 actin-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003868</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000099">
        <property type="protein sequence ID" value="KAL1893892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11524">
        <property type="entry name" value="SYLF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051702">
        <property type="entry name" value="SH3_domain_YSC84-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007461">
        <property type="entry name" value="Ysc84_actin-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629:SF8">
        <property type="entry name" value="DUF500 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G07310)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629">
        <property type="entry name" value="SH3YL1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04366">
        <property type="entry name" value="Ysc84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ysc84 actin-binding" evidence="2">
        <location>
            <begin position="273"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="480"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="367"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="517" mass="53160" checksum="D27478840FCFD39B" modified="2025-10-08" version="1">MTDSHASKAAEAGVPYYPPPPPGPPAQPHDRTQAPAESSYPPIPAYVPAEAAKQEALQSHPPYSSDSKAEHSAQVPVSSTTGPATFSHPNDKPLPDSHVPPVTPIAHTDSEEAAAAKGSAFSKWGKKLQQYGEKAALPINNLTNKMGMQSFLPMAMDRECDKAADIITSFTSKLNALIRLSSGTAMSKFTNTLIEDGVKVDKPVTSPGEKPTKEKSKSMIKIPPKVIANAVGIAVFTAVRAGFQIAGTTGSGVLVARLADGSWSPPSGVQVASLGGGFLMGVEVYDCVLVINNPAALAAFLRTRVSLGPEVAVAAGPYGVGGGAHVGAGAGSRGEKGSENLNPSAKHTAEESPNLAGVTQVPPVNVPATGTTATPSGAATLKPADKKHKRTSSGALKPVFSYVKSKGFYAGAQVDGTVIAERKEANAAFYGRPIGVERIIRGEVEAEAGTGATVQKLAWPTGGLRLLEALNKADVGAVAARTTEATPDPASVAGESPPPPFQDTGAAYPKDEKVSYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1K8</accession>
    <name>A0ABR3Z1K8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SCF ubiquitin ligase complex subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">GRR1</name>
        <name evidence="5" type="ORF">Cpir12675_003627</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000089">
        <property type="protein sequence ID" value="KAL1894501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050648">
        <property type="entry name" value="F-box_LRR-repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057207">
        <property type="entry name" value="FBXL15_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13382">
        <property type="entry name" value="MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13382:SF67">
        <property type="entry name" value="SCF E3 UBIQUITIN LIGASE COMPLEX F-BOX PROTEIN POF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25372">
        <property type="entry name" value="DUF7885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="75"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="F-box/LRR-repeat protein 15-like leucin rich repeat" evidence="4">
        <location>
            <begin position="206"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="854"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="854"/>
            <end position="882"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1894501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="897" mass="98922" checksum="3AE81540DC7FDED5" modified="2025-10-08" version="1">MSTVNLDGSGFDAPLTLETESSVSSAASPVPPDNDESDFYLINNDSGSSLSLSHEEREEREIARIQQECKETPVHRLPNEVMMMIFAKIDRPSDILRSMLACKRWARNSVDLLWHRPSCTSFEKMERICNALHAQIPFFQYWDYVRRINLSQIAKLVNDGTIDSLKKCNRIERLTLTNCKQVTDSGLISLVSQNHNMLALDISANQTITDQSILTVAENCPRLQGLNIAGCVNVTSQSLVTLANSCRQIKRIKLNDILNVTDEAVLAFAENCPNLLEIDLQMCHEVGNISVAALLSKGKALRELRLPYLHLITDNAFLPIPSKVTFDALRILDLTGCYELTDAAVVKIIDAAPRLRNVVLAKCRNITNVAVTAISKLGKNLHYVHLGHCSLITDEGARQLITSCNRIRYIDLGCCTALTDASVCLLASLPKLKRIGLVKCSQITDNTINSIASACNNRANRPNSDGTSGACLERVHLSHCMSLTLKSIIRLLNSCRRLTHLSLTGVPAFLTDDFQRFGRDPPPEFTEHQRQIFCVFSGNCVSHLRNHLNNSPQYEELRRSAGIYRPHGNSHFEVSSIAQIQEAQVLAPAPTVQNGILFEPDAWEPDLDEDDLMNDIDGPGGNEGGIGLMDMHQLQQNLPVIDNAHNHITPPVNPGVGHGHPAADPVALDNNNPHNTQILAENPHNQELIYNYFVSQIQAGLMPMPQPGEATYNLITIHEQNIAIQAAQLAAGNNMLNHAQNYENSHSSQVAHMPPLHAPSHSSLEPQILNQSVVHANNLHLAHAQAQFQAQVQAHAQAAAPAAVPAHTQVLAQSHSHSHLLGHHHLSQAQIQFQTQVQAHAQAQAQAQAQAQAQAQTQGQTQQNPQEQEQQQQPQQQQQQQPGIWNLDAVAFNSHHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1V4</accession>
    <name>A0ABR3Z1V4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase B complex (NatB) non catalytic subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_003756</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000094">
        <property type="protein sequence ID" value="KAL1894275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019183">
        <property type="entry name" value="NAA25_NatB_aux_su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09797">
        <property type="entry name" value="NatB_MDM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1894275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="957" mass="106439" checksum="72459001347AAA48" modified="2025-10-08" version="1">MSQYWNIPKLKRGVDLQVQSAYSDGDWQRVARLAAKHANMADRQYHEILKVSVESQMETPVSRYAAVAHAHKMLQEEVVILEIESFELLDWATKDIAGENFFHQVIGPLRLRAVKSGKLSRMAMVKCFEACLRNWDLESAQQIAAYHDRSFKQDRFFTFWNIAVTFLLATSDQHATEKRALYATLASRMALKANQDTIAAPKALALQEEEVLVYYTILSSQGSLKDWQDLLNNDTLGPVAQCRLGRKEPFLTALRAFENFEDWPSVYQLTKAGITDPESTDSTWKPSVLASDWVLWQYCLKSARYVYEANPGVIQEIRSLLEAASVESSAAINRRTIAMAKILACFELGTLSESGSNPDAIACMTEMVQKLTIVIRFEDLRPLVQRMSASDMDALLAAISNPLEDVSKPVAVVLKCALLGKLRLLIATCQQCPPDAFRAIARDACTNLRSLSQPLGETENSEISSLLKNMDISDARNTKLELSPDFSILIAVTLINLSGLTPGNICNSNFSYLLQAIAILENQLHITPKDHTVLILLVRLHILIGSAWRAKETWDVLDVKRTIVDSLAPLFLDRLSTISPVLVYSDRIVKTVLSYYETVFKTEMPKSIVEAIHARSYSSIIQIPKYIRSLKTSSTRAMGYFEKQRAHRAFTGKAEEWRMADVAVYSETIDFGPFPRLESSSVKPIYDTLSIGPKPSNTRTQLSILAEKFFSTLNCKPPSFYKPSPSAIVLDEVYVAEELSRLANMFGRYLSPDAADKLTPSEHTHYQVVALLTLFILSSCPPAAQAGAAKKPAVDAIISALGDLVFTIEERLSSTSDTTEKTLKFFSSLHDLWYIRDTANAIRVALDYITAFNGRQKPPKPPTKDVASNMKALATSSAAAMAKAKSWLASAKGVLTEPGFERKLVALAFAPAEDSDNELTHAVRITAGLEGSPSATWARAIVSGWKTNIIGWEQMKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1Y8</accession>
    <name>A0ABR3Z1Y8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Mitochondrial fusion and transport protein ugo1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_003859</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000098">
        <property type="protein sequence ID" value="KAL1894075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="153"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="168"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="516" mass="56322" checksum="03FB5A8B755C6EAC" modified="2025-10-08" version="1">MATPSYRESVNPLRPYYIPPSLAEQHGLAAGVSSTTSNVSSSAVNVTASAVKTSATATSAAGRYSSKARDMFSDLDYKDYISEPSPSVVTTARELLDDMMWKYTSVLMSQPFEVAKVLLQVRTCEEAQEAQVVEPIFETPKKPHPVASYSESGFGFGEGESDNEEPNYFTSGFEDSSNPFSHSSRKELDPFAEDEPLPPPKPTLPALPPHQLVLTKSNSINEVISQLWTKEGAWGVWKGSNSSFVYNVLQSLLENWSRSFLSAIFNVPDIGVKDDLDKLIGIASPYPWASLCVAAAAAVATGLILCPLDLVRTRLLITPASKGPRRTLSVLRSLPSYLCPSVLFVPTLLHSLVNPLLTLSTPLALRTQFRIDAEQSPMTYSFVKFCASAASIFIKLPIETVLRRAQTHVISSSEYVHAADPQGNALETIVPIGRYNGIFGTMYHIATEEGVRTVEPSTSKATSTSRVRKNRNKTSGPIYLKGQGLEGLWRGWKVNWWGLVGLWTANLVGSSGEGEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z202</accession>
    <name>A0ABR3Z202_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="5">PPIase</shortName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CYP10</name>
        <name evidence="7" type="ORF">Cpir12675_003730</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclophilin-type PPIase family. PPIL3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000093">
        <property type="protein sequence ID" value="KAL1894302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01928">
        <property type="entry name" value="Cyclophilin_PPIL3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF2">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="6"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1894302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="166" mass="17975" checksum="BDBDF95EEF2B7FC7" modified="2025-10-08" version="1">MSVTLHTTHGDIKIEVFCESVPKTAENFLALCASNYYNGSPFHRLIPGFMTQAGGPANPTPENPKGGRSIWGEPFADEIRSGLKHSGRGIVSMANRGPGTNASQFFLLFDKAPHLDGLNTVFGKVLGDAGLDTLTRIEAVEVDKKNRPKEVVKIERVTIHANPLAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z291</accession>
    <name>A0ABR3Z291_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutamine amidotransferase type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_004060</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000107">
        <property type="protein sequence ID" value="KAL1893629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051857">
        <property type="entry name" value="Asn_synthetase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45937">
        <property type="entry name" value="ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45937:SF1">
        <property type="entry name" value="ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="4">
        <location>
            <begin position="2"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="592" mass="65555" checksum="00DDD211E75AC2D3" modified="2025-10-08" version="1">MCGIYLSIGQAIATRSENLERRLDARGPDFLAVERCCIENLPGKSQSAAALPIYLEFTSTVLSVRGDHIATQPISTPAVQATPPDRAHPDRDLLCWNGEAWLINKLPVEGNDTEAVFALLSASSSHGELVQCLRQIRGPFAFAYLRVRDGGYRVYLARDRLGRRSLMRWRDPETQGLVFCSVSDGQQGAEEVPADGIYWVDVNTDDISSLKFEKEQWLVDVPQSEDLVGGLGVFNTSVPTDDEIEAHAQSRTVYDAARDLTAVLQESVRLRARDIPKLPQRVMEAQKASIAMSKAKAAVFFSGGLDCTVVARMLCENLPPNDEIDLINVAFENPRVAAQLRKEKGNVDDIYEECPDRITGRASFLDLCKTCPNHKWRFIAVNVPYKETLAHRGEVAALMSPHKTEMDISISLAFYFAARGSGSFYNSWEATDATSNSGRGTHGYGTTPARVIFSGLGADELFGGYSRCALIYSRQGYSGVIEQLKLDVGRLNTRNLGRDDRVISHWGREIRLPFLDEDVILWAIQRSVLEKCDFSTSNEHYSGIPPDKRVLRLVAKELGLGCLLEKKRAIQFGARSAKMETGKVTGTKEIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2D5</accession>
    <name>A0ABR3Z2D5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="4">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_004021</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Esterase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the carbohydrate esterase 1 (CE1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000105">
        <property type="protein sequence ID" value="KAL1893674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010126">
        <property type="entry name" value="Esterase_phb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050955">
        <property type="entry name" value="Plant_Biomass_Hydrol_Est"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01840">
        <property type="entry name" value="esterase_phb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037:SF5">
        <property type="entry name" value="FERULOYL ESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037">
        <property type="entry name" value="UNNAMED PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10503">
        <property type="entry name" value="Esterase_PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="1 4" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044987008" description="Carboxylic ester hydrolase" evidence="4">
        <location>
            <begin position="20"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="292" mass="30406" checksum="C000C1C741C556A7" modified="2025-10-08" version="1">MKVSSVLAAIGAFVSAANAASLTQVTSFGNNPTGAKMYTFQPDNLEKGAPVVLVLHYCGGTANAMYANTGWATAAAKYGFTVIYGETPNASGCWDVSSPATLSHDGNGDSTSIANMVRYAVQEPNIAADPKRVFVTGISSGAMMTNVLSAAYPELFAAATSYAGVAAGCFYTGSVAGWNSTCSSGQSIHTPQEWASIAKAMDPGYNGPRPSMTLYHGTEDTTINSQNLQEALKQWTGVFGYSMTGGQASQNQPINGWTTTVYGPKVRGVVAQGVTHSISMQVDNDLKLFGIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4P9</accession>
    <name>A0ABR3Z4P9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1770 domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_003312</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000076">
        <property type="protein sequence ID" value="KAL1895295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013898">
        <property type="entry name" value="Atg43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38699">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38699:SF1">
        <property type="entry name" value="MITOPHAGY RECEPTOR ATG43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08589">
        <property type="entry name" value="ATG43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1895295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="158" mass="17941" checksum="1284844C72505A38" modified="2025-10-08" version="1">MTSAAAKGVVEALKATQPQNAFQNADPRDAPATSQGETFVLEHKGSSPGSYDYYSEDILVPPQKHKLPAIPDLRFEQSYLQSISKADTWWKVALITIRDQMIMPMMQGIVYNLFLCGWQQWNRSAQIHGTSLGARVRRWWYGVNNWPVPPAPVVRRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4R6</accession>
    <name>A0ABR3Z4R6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pre-mRNA-splicing factor SLU7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SLU7</name>
        <name evidence="10" type="ORF">Cpir12675_003661</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SLU7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000090">
        <property type="protein sequence ID" value="KAL1894484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021715">
        <property type="entry name" value="Slu7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039974">
        <property type="entry name" value="Splicing_factor_SLU7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12942:SF2">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR SLU7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12942">
        <property type="entry name" value="STEP II SPLICING FACTOR SLU7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11708">
        <property type="entry name" value="Slu7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Pre-mRNA-splicing factor SLU7" evidence="9">
        <location>
            <begin position="118"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="154"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="405"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="173"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="463"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF11708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1894484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="491" mass="55347" checksum="565FB415EA212F40" modified="2025-10-08" version="1">MASSPDPETKRGDKFSTAAKEENIYIPAFISKRPFYANDTSADYLGHQRLQKKDEETKWYDRGKRAAPAATKYRKGACENCGAMTHKVKDCLSRPRARGAKWTGRDIQADEGLQDVKLGWDAKRDRWNGFDAKGFRSVVDEHNQMEELRREVQRAARANDPDAAAGGDDALDAGDKYAEQNDMSKHQATSTRQLRIREDTAKYLLNLDLDSAKYDPKRRTLVDAGATADKAAETFAEQGFMRSTGDAVEFDQAQRYAWEQQETFGNTSQHLQANPTSGEYQRKLIREAEERRKAEKSKLLQDKYGVSLEANNSGEGATTAALRAMAVTENETFVEYDELGLVKGAPKKIVKSRYTEDVFPNNHTSVFGSWWTNFKWGYDCCHSFVMNSYCTGEDGKRAWENSEKQRNGIPMIENSSSAAAVGGVEKPEAKTETEEETQGEAEPPAERRRAKKRTAADMMNGVTEKELEEYRRRRTAAEDPMAQHLGKDDLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z504</accession>
    <name>A0ABR3Z504_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_003319</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000076">
        <property type="protein sequence ID" value="KAL1895302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1895302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="266" mass="30228" checksum="A6B9A150B451868C" modified="2025-10-08" version="1">MELSKRPKTSFNFSSLPTELRLYVIELLASNWTSEHPSIKDIPLAPLASVNSEWQYVIERFTFSTVSVDLGGIEMLKRFSRRRKKLVNVMVLKVTLPEYPNNPCESKETWKEKVKNNKVFRDTIIAVYTALSSWDEDEVKPGGFALTLKVWSVSDFNQCSTELWQERLASHRDIGALRFNESYLDIAGFDDEGTRFIDIPYVYVVGYFSVDTNIPRVINPAAISEMVASLRLVRAVYLGVAKHTEGIHGTPANYKGKQAYDESLAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5Y6</accession>
    <name>A0ABR3Z5Y6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Solute carrier family 35 member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_003008</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC35F solute transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000065">
        <property type="protein sequence ID" value="KAL1895968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009262">
        <property type="entry name" value="SLC35_F1/F2/F6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052221">
        <property type="entry name" value="SLC35F_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14233">
        <property type="entry name" value="DUF914-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14233:SF4">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER F2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06027">
        <property type="entry name" value="SLC35F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="321"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="347"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="422" mass="46795" checksum="2BEF009154512D8B" modified="2025-10-08" version="1">MDDIKHNPGSAAEVARSTSSAGTKVSPVVVDKDLATTTTSSVDDEALLSQGFQVIQEEQVTWYSYLKTVDFWLVVIMGQVLSLCITTTNTFSSFLAQHDTNIPSFQSLFVYILLSIIYTSVFFYRWGWRRWFVVLKTDGWKYLIMAFLDVQGNYFTVLAYRYTNLLSAQLLNFWSIVCVVVISFFLLRVRYKPFQIIGILICCGGMGILLGSDHITGSNSGPGANIIKGDLFGLLGATLYGISNVFEEWLVSKSSMPEVLSFLGTFGSIIMGAQAAIFDRSSIQNANWDGKVYGYIAGFTAAMIIFYTIAPFMFRMGSSAFFDISLLTANFWGVIIGVKVFHYTIHFMYPIAFVCIIIGLVIYFLSGSILGDSKKPWLGDNQEDGVAGYCTAKLKALNAAKKRQQEQELRQAAAEATTVQAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z624</accession>
    <name>A0ABR3Z624_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003458</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000082">
        <property type="protein sequence ID" value="KAL1894964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046540145" evidence="3">
        <location>
            <begin position="21"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="353" mass="36203" checksum="D8B35783273EACDE" modified="2025-10-08" version="1">MKLITSFSHCLLFLAPATQSARVSGRRGFGVAFLQQELAVLQPRDDPSCLANQHNCGEINQPGLCCGASQYCFVQTDSSVGCCSETDACVPDICKSTGYLCTTTTTSSGTITTQKTCCSRLCPTGSFFCPSASGVGSEDIGCCAYGSTCEGTGGCVGSAVATITGTSATPDITPVNCATDQRPCANDPNGCCPASADCSVSSNGDVFCVITLSDGPTSSASSSVPSPSASPSLSSLSGGAKAGLAIGLIAATGMLSFVGYVLWQKYRDRRAHFSEGTMSETEQDDTTTMSANRPQNIYTGPDASVGPWTYTGPDAGVGLLRTTNARGVVGNPQHPGEIMEPVEIDSGVQESPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6J0</accession>
    <name>A0ABR3Z6J0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002888</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000061">
        <property type="protein sequence ID" value="KAL1896241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="218"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="309"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="343"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="382"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="510" mass="53374" checksum="7EB119A7AA6D48AF" modified="2025-10-08" version="1">MASASKNPFRRSGLGSPPPPAISTTNLALRPALVSSSVFGPDADTTDSEASDLSASTPRSKTSKKVRVQSPPPSPHISQSALISRKRSPSPSRSLSPPLATQDPAPVLAPALDLESPVDPVDAQIPDQENDDDDQDSTPESTPRTAGPPHNPFSKTLQDMKDLTSEARTPTSPKSARSHSAKTSLDVQAFQRLLLTGSTGLDQATSPRPAAESPVFESASRSPSHNSRSPPQISSHVPNAESPSPPSSQPSAPTHPHKKPPPPPSSRHGRSIKSVDLTHMTPPLTSPQRPSPTLPPALNSPPNPAVSLAPGRPDPGSRAPAPPPPPRRMQHKATIVPSRTEEASASASTTTAQLEIPTEPYASGAASPTYDEIDLSTRSPVLSASLRSTSTTTPLSPASTLHIAKVKPQPPPTRNPSVRRPKNLVRTASATKPELSRKPSNASNRSHAPPPPPTPRQRGWSKGSADEGAVGAKKSADLQPIITSDAENDILAEINALQKEVEAAMKGGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6W7</accession>
    <name>A0ABR3Z6W7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription elongation factor Spt6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SPT6</name>
        <name evidence="11" type="ORF">Cpir12675_002812</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the SPT6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000059">
        <property type="protein sequence ID" value="KAL1896408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09928">
        <property type="entry name" value="SH2_Cterm_SPT6_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09918">
        <property type="entry name" value="SH2_Nterm_SPT6_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.650">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2740">
        <property type="entry name" value="Spt6, Death-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.850">
        <property type="entry name" value="Spt6, helix-hairpin-helix domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3500.10">
        <property type="entry name" value="Tex N-terminal region-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="entry name" value="YqgF/RNase H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049540">
        <property type="entry name" value="Spt6-like_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028083">
        <property type="entry name" value="Spt6_acidic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042066">
        <property type="entry name" value="Spt6_death-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032706">
        <property type="entry name" value="Spt6_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028088">
        <property type="entry name" value="Spt6_HTH_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035420">
        <property type="entry name" value="Spt6_SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035018">
        <property type="entry name" value="Spt6_SH2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035019">
        <property type="entry name" value="Spt6_SH2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028231">
        <property type="entry name" value="Spt6_YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055179">
        <property type="entry name" value="Tex-like_central_region"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023323">
        <property type="entry name" value="Tex-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023319">
        <property type="entry name" value="Tex-like_HTH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017072">
        <property type="entry name" value="TF_Spt6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10145">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR SPT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10145:SF6">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR SPT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14635">
        <property type="entry name" value="HHH_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14641">
        <property type="entry name" value="HTH_44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14633">
        <property type="entry name" value="SH2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14632">
        <property type="entry name" value="SPT6_acidic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21710">
        <property type="entry name" value="Spt6_S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22706">
        <property type="entry name" value="Tex_central_region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14639">
        <property type="entry name" value="YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036947">
        <property type="entry name" value="Spt6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55550">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158832">
        <property type="entry name" value="Tex N-terminal region-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="11" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0727">SH2 domain</keyword>
    <keyword evidence="6 8" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="S1 motif" evidence="10">
        <location>
            <begin position="1097"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="61"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="88"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="126"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="161"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="178"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR036947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1896408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1409" mass="163131" checksum="1FD21E208C6FE3E0" modified="2025-10-08" version="1">MSSSLKDLIDGEADLDDEDESFDEEDSRSGRRAERPAIDDSSEEEEEEDEEEMRKVQEGFIVDEDEDDVEGSDVEARRRRKRSHRDREEDEMLDDEDLELIGEGQDWKQKTHEKPKYKRLKSGAQKAEDRSTARRGLDDIFDDDEEDDRAYSRSGYRQQADEMDDFIEDDYPDEDDDDRKRAQEEAEVARPRAEKGVGSMIDTTGLDKDALQDMEDIFGDGGDYAWALELEEEEQDQEKEEQNIELKDVFEPSQLKERLLTDFDNEVRFTDEPERFQIDRRPFANLQLTDDQLKEEARWIVEMLWPKKDLSMDYHGHFLKCVSKVLEFFLVDEVEVPFIFRHKKDYLIYSKKIPNPERRHNPDAPEFKTEGKRLLSQEDLWRILDLDLKFRSLVEKRNALSKAYGNLKETLNISDPILDEMMPQAATLEELQDLQDYFNFQYSAEIRDSSIGSGNATTKRPGSKNTFYERIRKSPVYKFVRAYGLSADQLAKNALGQGRKATAEDDSKDPISLSDNLICEDFSTSESVLNAARSMFTEELFFNPRLRKFFRLHFYQNGEFDCRRTEKGLRKIDEAHPFYEVKYLIRQTIHDMARKPELFVKMLKGEEEGLLEVKLELRSRGEFRKRLDGEFESENYSDIAQSWREERRRVLDMACAKLERVVTKGVKESVRTACNDELLLASKEEFYRRLDQAPYKPKGLTLGTTPRVLTLSVGLGDPARDPIFYTFVDEQGRILEHGRFHNMSRKDEEREKFTNLVKDRQPDVIGISGFSADTQKLIRDVETLVMDRNLRGPEYEDSEGELQADLLDIFIINDEVARLYKDSPRAVAEHTTLHPMTRYCFGLARYMQDPVKEYAALGKDMVSLSIHPCQKLLPEDKFRKILETAMVDIVNLVGVNINDAVQDPYYANLLPFVSGLGPRKATNVIKAINANGGSIASRDELVGDPDSGKLPVVGPRVWNNCASFLYIDLDTTNPAADPMDSTRVHPEDYELGRKMVADALDLDEEDVKAETDDHGPAAIVRKLFRDNDQYRINELILEEYADQLENNYSQRKRATLEAIRFELQAPYEEIRKSLMVLSPIEIFTMFTGETKDSLACDMIVPVNVRVVKDDFAIVKLDCGVEGRVEALEVNSRGHIRDTLQVGLTTQAKIIEVNFKDFLVKLSMRPELLRRGYRRPVDYGSDQWDFNQEDKDREDLREKDRSTGRAQRVIKHPLFKPFNGMQAEQFLGSQPNGEVVIRPSSLGNDHLAVTWKVDNGVFQHIDVVELQKENEFSVGKTLRIGGKFTYTDLDELIVEHVKSMAKKVEQLMRNDKFHRGSRADLEKWLTTYMEANPNRSTYAFCIDSKHPGYFWLCFKASKTARVSAWSVKIIPHAFQMMNSEYPDMRALCNGFKLRHQNEVKMAMQKLQIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7F5</accession>
    <name>A0ABR3Z7F5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_002863</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000060">
        <property type="protein sequence ID" value="KAL1896270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051556">
        <property type="entry name" value="N-term/lysine_N-AcTrnsfr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42919">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42919:SF8">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="81"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="16"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="293"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="304"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="327"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="350"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1896270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="374" mass="39646" checksum="7042E0F172B74BEF" modified="2025-10-08" version="1">MSQASITSWFKSAISPSTTTTAVSQQPLRTSQKATPAPPPPPQSKYASPLSSSTPPSTSISSYSSRPASPPAVPLNIHPNAVLRPITAADIPAVRRVLSLMLAVYYADSFFKPISTGAHASRHSRVITWSDPISPARPPTIIGVIVCRVESRPAHDGPESALYLQALCLLSPYRGLGLMTMALDAVTRAAKTDGVKVVDAHVWTASEDALAWYELRGFYRSDTPIEGYYQKLDPASAWVVSREVVSTKEEKKALSRASSIAGPMATAAVKLMPFDASPATASSVSSLSSVSAAVDETKSESEPPHATASPSSASQVPPPPGPPRGMSFQNTAPPTSWNDLPQDMAVGSMKATTQTKTTAGSRKKRDRSYPVPTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8I4</accession>
    <name>A0ABR3Z8I4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Histone-lysine N-methyltransferase, H3 lysine-9 specific dim-5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_002557</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000051">
        <property type="protein sequence ID" value="KAL1896976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.225.20">
        <property type="entry name" value="Ub domain-containing protein, DC-UbP/UBTD2, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032752">
        <property type="entry name" value="DC-UbP/UBTD2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038169">
        <property type="entry name" value="DC-UbP/UBTD2_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050973">
        <property type="entry name" value="H3K9_Histone-Lys_N-MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007728">
        <property type="entry name" value="Pre-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46223:SF3">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SET-23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46223">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05033">
        <property type="entry name" value="Pre-SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16455">
        <property type="entry name" value="UBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00468">
        <property type="entry name" value="PreSET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50867">
        <property type="entry name" value="PRE_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Pre-SET" evidence="11">
        <location>
            <begin position="76"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="10">
        <location>
            <begin position="173"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="9">
        <location>
            <begin position="593"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="333"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="341"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="378"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1896976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="673" mass="74537" checksum="5DA5B4F5FE22404F" modified="2025-10-08" version="1">MEADMRNHFFKHGKPGFDEEKKRCHWCQIKSFPSHKLAPITIVNDIDDTVMPRNFRFISTIQYSVGVAPVEDSFRSGCECLDDRSCHSRSCSCLGEVVSGDSSDDEGGGRGNDRGSSVPVKKMLLTAYCVRGPRIGLLRQTALESLAPIYECHQACACSRNCVNRVVERGRTVPLQIFRTSDGRGWGVRSTIDIRAGQFVDKYIGQIITATEADRRRELAELQQQKDVYLFELDKFFDPASIDERLSAPPLFVDGEFMSGPTRFVNHSCNPNMKIFVRVGDHADKHIQDLALFAIKNIPAGTELTFDYLNGKVDGEEDEDDPAKVAEMGCCNSIEQGPYQDPSSDPSSTSNITAGAAPAPAHSTPVTGSALSLPGAISSASAPTHSQSSRSRPRPRPRPQRTPSEQRHLHRAAITTAINTNNVAPETIYNQPLRRKRWNSRAGQRWTVARIDRCRREFFDTRDDGKPEIWQSLRAALEILWASDRAQEIGDARNVAISTAQSIIDAAGITIPTGNPSHGVYDSRGFLYQLPKEIICDPQDIVQLDSDSDSDSAVTAEDDEEHFLNDQQTKESVIDNILSPPSISASGTTLSLVKFTARLNEGARDIEVEIGRSDPVRIVKKAIVAKAELPPHRHVRLVYMGRLLRDGESLEKQGWQMGHVVNAMVFTKPRSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8J8</accession>
    <name>A0ABR3Z8J8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Acetyl-CoA C-acyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_002697</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA</text>
            <dbReference type="Rhea" id="RHEA:21564"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="2.3.1.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000055">
        <property type="protein sequence ID" value="KAL1896675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050215">
        <property type="entry name" value="Thiolase-like_sf_Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853">
        <property type="entry name" value="3-KETOACYL-COA THIOLASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853:SF10">
        <property type="entry name" value="ACETYL-COA C-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="8">
        <location>
            <begin position="29"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="9">
        <location>
            <begin position="292"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1896675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="414" mass="43795" checksum="14C898A14C709071" modified="2025-10-08" version="1">MTERVASLLSHLAPGSSLSKIQQKNPDDVVITLAVRTPLCKSFKGGFKDSQLEDIVFLLLQQVKQRSGLDLKLVEDICLGNVSDSKACYKLRCAALAAGFPNTTSAYSVNRFCSSGLKATADIAAAISTGSIEIGLAVGAESMTAGGDKIEEPFSQTVLDASQEARDSIESMGWTSENVAKDFGLNRQALDEYAAESYRRAEQAQKTGAFDDEIVPIVAKVKGPDGALREVTLTKDEGIRPGTTAEKLSKIRAAFPQWGGATTGGNASQITDGAAAVLLMKRSTAQRLGQPILAKYVGSTVAGLSPRIMGIGPTVAIPKLLSQHNITLSDIDVIEVNEAFATMAVYTKDFLGLDYQKMNPKGGAIALGHPLGCTGARQIVTGLSELRRQKKKMLLTSMCIGTGMGMAGLFVNEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA18</accession>
    <name>A0ABR3ZA18_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA ligase</fullName>
            <ecNumber evidence="1">6.5.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">trl1</name>
        <name evidence="6" type="ORF">Cpir12675_002563</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + (ribonucleotide)n-3'-hydroxyl + 5'-phospho-(ribonucleotide)m = (ribonucleotide)n+m + AMP + diphosphate.</text>
            <dbReference type="EC" id="6.5.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRL1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.3" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000051">
        <property type="protein sequence ID" value="KAL1896982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003972">
        <property type="term" value="F:RNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019039">
        <property type="entry name" value="T4-Rnl1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012387">
        <property type="entry name" value="Trl1_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015966">
        <property type="entry name" value="tRNA_lig_kin_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015965">
        <property type="entry name" value="tRNA_lig_PDEase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32004">
        <property type="entry name" value="TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32004:SF1">
        <property type="entry name" value="TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09511">
        <property type="entry name" value="RNA_lig_T4_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08302">
        <property type="entry name" value="tRNA_lig_CPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08303">
        <property type="entry name" value="tRNA_lig_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019634">
        <property type="entry name" value="tRNA_lig_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="T4 RNA ligase 1-like N-terminal" evidence="5">
        <location>
            <begin position="58"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA ligase kinase" evidence="4">
        <location>
            <begin position="384"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA ligase phosphodiesterase" evidence="3">
        <location>
            <begin position="544"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="598"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR019634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF09511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1896982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="795" mass="90171" checksum="16632500217A7E39" modified="2025-10-08" version="1">MIAALEARRQAGASNNKKRGGGSFKKTGFPVGQSPSGINVYSWRLSDWDYKLRDLPTYARGLFTTTNSLQKDEVAVRGYDKFFNVNEVHETKWENIKTQTKGPYELTLKENGCIIFISGLEDGSILVCSKHSTGPGPDSKASHSTIGEGHLRKQLEKIGRSVQDLARELRARNATAVCELCDDEFEEHILKYGPEQAGLYLHGINLNIPEFVTYPSAQVQGFAQEWNFKKTDMLVMQDIDKVREFLNSTAESGAYEGRDVEGFVIRCRRAPTPDSPFSDWFFKYKFEEPYLMYRQWRECTKALIAGHKPRIAKHKTITEKYLFYVKKRMAKDPSLGEKYLKNHGIIALRDDFLASENLKGGEAANMERDSDSKETFPEVTKDVIIAPIATIGCGKTTIGLALTMIFGWGHIQNDNISGSKRPPRFVAALKEELKTKPAVFADRNNAERRERKQLVTDLRLSMDEPTIVALNFKHSPDSIQDIRELTRERVLKRGDNHQTIQAASDTNKFLGIMNNFINRYEAVDPDNGPDTGFDYIINLDTLAGSRANLENIVKDLHETFPNFISQMPSQEQLDAAMEYALNYKPEFRHEIRDRNNKWGKGVNQQQQQGSQTEKPKKKPNLEYMSVNVSKEVIDSTLQKTFTKPGISPENTKLYNYLKAQGRIQSSFHVTLLHRAGAKGHPELWEKYKSLFDSEYKATGEIGKLGTNKVVLERVVFNDKIMAIVVRLHDPTNTWVCTNKIAHITVGTYDNTTKPHESNDLLAEWLESGPKGVIREISLEDRPEVDGHVMGVAQRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAV5</accession>
    <name>A0ABR3ZAV5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002547</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000051">
        <property type="protein sequence ID" value="KAL1896968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1896968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="130" mass="14255" checksum="FA53A6CD53883283" modified="2025-10-08" version="1">MAVKHRAYDNFDESTKNSAYDYIKIGCKQLGFDEVPTIGLMMCLRCKSTGTAARPPSGDNKTNLGIILSVGLDSEQYPVSVGSRTRSGSPGNEQVLEVLQSLISEVNKMVVKENNKDACQYLAFQSKFLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBK3</accession>
    <name>A0ABR3ZBK3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Polysaccharide biosynthesis domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000038">
        <property type="protein sequence ID" value="KAL1898051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3560.10">
        <property type="entry name" value="yst0336 like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023139">
        <property type="entry name" value="PBDC1-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008476">
        <property type="entry name" value="PBDC1_metazoa/fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021148">
        <property type="entry name" value="Polysacc_synth_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13410">
        <property type="entry name" value="PROTEIN PBDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13410:SF9">
        <property type="entry name" value="PROTEIN PBDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04669">
        <property type="entry name" value="PBDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Polysaccharide biosynthesis" evidence="2">
        <location>
            <begin position="27"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="161" mass="18620" checksum="C624FAEBB9286FD8" modified="2025-10-08" version="1">MAELPLTSTAKTPKNFNPEQADNLEDIEKQFAVKAVQHMEVYMRILQTVPGSTVRLTKIDDEIMEHLAKDFPEFDPAKPIDENEMKSSRGKECWRNFMMAYEKRVDDYNFGTVMRIAPNTDYGQHTTIFVPRMQFYAIEIARNRAGLNDWIHESAKRSGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBQ8</accession>
    <name>A0ABR3ZBQ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histone deacetylase</fullName>
            <ecNumber evidence="3">3.5.1.98</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">HOS2</name>
        <name evidence="11" type="ORF">Cpir12675_002049</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histone deacetylase family. HD type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000036">
        <property type="protein sequence ID" value="KAL1898101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141221">
        <property type="term" value="F:histone deacetylase activity, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003084">
        <property type="entry name" value="HDAC_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF36">
        <property type="entry name" value="HISTONE DEACETYLASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01271">
        <property type="entry name" value="HISDACETLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="10">
        <location>
            <begin position="121"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="494"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1898101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="536" mass="59731" checksum="B1F072E0A7D97653" modified="2025-10-08" version="1">MDYQFPGRAGMAVAAASESTSASTPAPANEPCSAAINPPFEFKFRTPKPNYLPHISDKGDDYSIIDEHALPLEQHGLEAYEKYYSQCEKQALDMGIERPNGYTVSFHCNPEMEKHHFGQTHPMKPWRLTLSKSLISSYGMMFAMDNYLSRAATYEELNEFHSSDYLDFLGTVQSEPTPREYDSTEDIKFSLGGSDCPIFEGLYDYASMSAGGSIDAARKICNGQSDIAIAWGGGLHHAKKNEASGFCYINDIVLSILQLLRYYPRVLYIDIDVHHGDGVEEAFWSSDRVMTCSFHKWDPNNFFPGTGALEDNGPKSEHNPGAHHAVNVPLLDGITDEQYKQLFQTVIGTIVQKFRPSAIALQCGADSLAGDRLGRFNLQVQGHGACAEYVKTLGVPVIMFGGGGYTPRNVARAWAYETSVAIGYNDKIKENATLPMHTPWRNEFRQDTLFPTIEQILGEPRQNKNTQKKLAEIVAHITEQLRFVEAAPSVQFREIPPGTDAMRDQVDAAMSEEGAEKDDRIRKRKERSVGTPMELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBT7</accession>
    <name>A0ABR3ZBT7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EVE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_002335</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000045">
        <property type="protein sequence ID" value="KAL1897480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21133">
        <property type="entry name" value="EVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.590.10">
        <property type="entry name" value="ph1033 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052181">
        <property type="entry name" value="5hmC_binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002740">
        <property type="entry name" value="EVE_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047197">
        <property type="entry name" value="THYN1-like_EVE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14087">
        <property type="entry name" value="THYMOCYTE NUCLEAR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14087:SF7">
        <property type="entry name" value="THYMOCYTE NUCLEAR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01878">
        <property type="entry name" value="EVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EVE" evidence="4">
        <location>
            <begin position="128"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="55"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1897480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="299" mass="33627" checksum="351E36EE4612C7B9" modified="2025-10-08" version="1">MARKRAATQTETTEGHEPKRRASARLRGSDTTVAAQIDVPIYNASTRVPRKSKRKLPEASDRESEEEQKPQTHKLKTALKATAAPKPKAKPSTSSNSIQGLAISDADPDSDSLPEVNPEIDRHDGEWYFLMKAEPETRYENGIDVRFSIDDLRACKKPEPWDGIRNYAARNNFKAMNYGDKAFFYHSNTKEPGIVGIMEVVREYSEDVSARRPGTAYYDPKSTKENPKWGLVHVRFVKKFAVPIGLQELRQLGNAGKLNDMQMLKQTRLSVSKVGQKEFRLLCDLADQKAKAAGLEHIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCE0</accession>
    <name>A0ABR3ZCE0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Survival protein SurE-like phosphatase/nucleotidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001982</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000034">
        <property type="protein sequence ID" value="KAL1898356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1210.10">
        <property type="entry name" value="Survival protein SurE-like phosphatase/nucleotidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002828">
        <property type="entry name" value="SurE-like_Pase/nucleotidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036523">
        <property type="entry name" value="SurE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027746">
        <property type="entry name" value="TTL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004344">
        <property type="entry name" value="TTL/TTLL_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00087">
        <property type="entry name" value="surE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47551">
        <property type="entry name" value="TUBULIN--TYROSINE LIGASE PBY1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47551:SF1">
        <property type="entry name" value="TUBULIN--TYROSINE LIGASE PBY1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01975">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03133">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64167">
        <property type="entry name" value="SurE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51221">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Survival protein SurE-like phosphatase/nucleotidase" evidence="2">
        <location>
            <begin position="3"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="519"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="519"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="764" mass="84185" checksum="6510F8379AE2ECD1" modified="2025-10-08" version="1">MHILVTNDDGPPSPHSSPYVHTLVRQLKAAGHTVSVVLPHAQRSWIGKAHIIGQTVKPVYYRPGNASHGDGPEAQGSVHKFPQASPAEEEWVLVDGTPASCVQIGVHHMFKHKAPIDLVVSGPNFGRNTTAVFALSSGTMGAAMEAAVCGFKAIALSYAFFTQNHDPDIIEAATRHSVRVIEAVYKQWPADKSIDLYSINVPLVGEVEVNKTMWTDILQNYWTEGSCFEEIDGGAEDDDADLQEENIRQGSIQSETNGPVSGHSHRHFKWAPKFAGVYKSVEESEPGNDGWIVKEKLTSVTPLKANFFQAGHHLHGKELELSSSTTSANPGPSSLFAAIKYDDPYVQPIIVSALERLFPGVFKMLSPEVKGDDPISLATYIPDTSKVLQIMAYEALDFDYAAQNSSTAFINSYMIRKALIRKHYLSLAVQHWIAKHPESILRKAVKPSDAFEVDYAEFLDDSLIEAFDLRQSMDENESRNAEDRQWWILKPGMSDRGQGIRLFSTMDELQDIFDEWEAERPDSDDEGDVGEDAHSADGSAVAQDGAGPGGHYITASHLRHFVAQQYIHPPLLPAGDNRKFHIRTYVMCTGRMSVYVYDDMLALSAGRDYTAPWADTNLDAHLTNTCRQDELPEGAEPVVRRLSEVAFPPDSTSYATLRMQIGEIVGDLFEGAARAMAMHFSPLANAFEVFGVDFLVGADGTPYLLEVNSFPDFRQTGDKLSAVVEGFWVETLRHAVGGFFGLQASKPAADEPQLQLVRKVELGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDF9</accession>
    <name>A0ABR3ZDF9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ABC1 atypical kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_001939</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000033">
        <property type="protein sequence ID" value="KAL1898394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13970">
        <property type="entry name" value="ABC1_ADCK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034646">
        <property type="entry name" value="ADCK3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051409">
        <property type="entry name" value="Atypical_kinase_ADCK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43851">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43851:SF3">
        <property type="entry name" value="COENZYME Q8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="6">
        <location>
            <begin position="382"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="38"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="183"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="55"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="747" mass="82216" checksum="D1B2E175896BCB84" modified="2025-10-08" version="1">MRLADFLVDLASVASASKAVVSKHAALRMRQVERYGQTSSIISSMKKRTRQNTQTPTATEAATTEPPTSNVPSTTSTATTASPAAPAGSPISLPPTPSLPSAANLGTTQGPLSQLRQEDRLNFGLGAPTRIPKLEPTTEAGFRATNDSLPTSINVNVFRTRRGSGLIGGKKREVPAVLVETGGERKPHPFAGNRLPGQLTRPKDKPSVKPQEPLKISHEALAKIKTEFPGEAVAEAKPEVAAEIRMEPALEVGAEIDTKSETLTSTEIRSSLFSQSSAESQINPILQQSHDLRESRVPSTRIGRLWNYSGLAAGMLGGAIGETFSRAVGGGSEGSLLLTPANMERLVGKLSRMRGAALKLGQMMSFQDTKMLPPQLQMVLQRVQDRADYMPSWQRDKVLINNLGSEWRELFTEFDEKPIAAASIGQVHKAILKDGSKVAVKIQFPGVAESINSDLDNLSMLLTATKLLPKGLYLDKTIANARLELGWECDYEREAQCAIRYQRLLSAEAEQYSAFIVPKVHLHASGKQVLTMDWMEGTAVTRIKYFTQDQRDWIGTQIMKLCLREITEFHFMQTDPNWTNFLYNQSRHKLELLDFGASREYNATFIRKYCELLYSASRGDRKGISALSLDLGYLTGHESNAMLNAHINSILTLAEPFLGSAPDIYDFKDQTITERVKSFIPVMLRERLTPPPEETYSLHRKLSGAFLLCAKLGSRVPCKAMFQECVAKQLATENQPFPTEGKRGEGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEY5</accession>
    <name>A0ABR3ZEY5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpl22</name>
        <name evidence="4" type="ORF">Cpir12675_001755</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000029">
        <property type="protein sequence ID" value="KAL1898752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002671">
        <property type="entry name" value="Ribosomal_eL22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038526">
        <property type="entry name" value="Ribosomal_eL22_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10064">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10064:SF31">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL22A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01776">
        <property type="entry name" value="Ribosomal_L22e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="123" mass="13950" checksum="7CD5248EFC5F027B" modified="2025-10-08" version="1">MAPQKKNVKGPKVTKKFVINASQPASDKIFDVPAFVKFLQEKIKIDGRVGNLGDIISVTGTPDGKIEILAHNELSGRYLKYLTKKFLKKHQLRDWLRVVATSKGVYELKFYNVVNDEAEEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF04</accession>
    <name>A0ABR3ZF04_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">1,3-beta-glucan synthase</fullName>
            <ecNumber evidence="3">2.4.1.34</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">1,3-beta-D-glucan-UDP glucosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">FKS1</name>
        <name evidence="14" type="ORF">Cpir12675_001854</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[(1-&gt;3)-beta-D-glucosyl](n) + UDP-alpha-D-glucose = [(1-&gt;3)-beta-D-glucosyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21476"/>
            <dbReference type="Rhea" id="RHEA-COMP:11146"/>
            <dbReference type="Rhea" id="RHEA-COMP:14303"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37671"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.34"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.34" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000031">
        <property type="protein sequence ID" value="KAL1898650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003843">
        <property type="term" value="F:1,3-beta-D-glucan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026899">
        <property type="entry name" value="FKS1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056261">
        <property type="entry name" value="FKS1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003440">
        <property type="entry name" value="Glyco_trans_48_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12741:SF48">
        <property type="entry name" value="1,3-BETA-GLUCAN SYNTHASE COMPONENT FKS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12741">
        <property type="entry name" value="LYST-INTERACTING PROTEIN LIP5 DOPAMINE RESPONSIVE PROTEIN DRG-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14288">
        <property type="entry name" value="FKS1_dom1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23605">
        <property type="entry name" value="FKS1_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02364">
        <property type="entry name" value="Glucan_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01205">
        <property type="entry name" value="FKS1_dom1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="497"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="545"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="585"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="618"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="749"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1351"/>
            <end position="1370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1403"/>
            <end position="1424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1520"/>
            <end position="1538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1609"/>
            <end position="1631"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1651"/>
            <end position="1678"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1690"/>
            <end position="1715"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1721"/>
            <end position="1743"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1787"/>
            <end position="1810"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1851"/>
            <end position="1871"/>
        </location>
    </feature>
    <feature type="domain" description="1,3-beta-glucan synthase component FKS1-like" evidence="13">
        <location>
            <begin position="351"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="32"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1898650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1946" mass="222363" checksum="5C8C91CDFC2620E8" modified="2025-10-08" version="1">MSAHPDGGNGHQGYDDGYNSQGHAQGQGHGGQDQYYQDDQYYDNGYDQNQRGGNDGYYDNSGYYNADSNNAYHQDGGYYDNQDQYQDTYYGNGQGGGAQGYDQGYDNAGFENRGGRPHGSEDDSETFSDFTMRSDMARATDMDYYGRGDERYDGYDQGQGGGRAFRPPSSQVSYGGNRSSGASTPNFGMDYSNVLPAGQRSREPYPAWTSEAQIPLSKEEIEDIFVDLTAKFGFQRDSMRNMYDHLMIQLDSRASRMTPNQALLSLHADYIGGDNANYRKWYFAAHLDLDDAVGFANVTKGKGLKKQNKKKKKGGDAEQTEAEQLQDLEGDDSLEAAEFRWKTRMNRMSQHDRCRQIALYLLCWGEANQVRFMPECLCFIFKCCDDYLNSPACQNQTDPVDELTYLEKCITPLYKYCRDQGYEILDGKYVRRERDHKQIIGYDDCNQLFWYPEGIERIVLEDKSRLVDVPPAERYMKLGEVSWKKSFFKTYKETRSWFHMVVNFNRIWIIHITMFWFYTAFNAPSVILGDEYEQQVNNQPETGKLFSIVGLGGAFASFIQILATICEWTYVPRRWAGAQHLTKRLLFLLLVFALNVAPFVYIFMVATDTTSKKILKYVGIGHFALAMHTFIFFAIMPLGGLFGSYLTKNSRRYVASQTFTASWPRLKGNDLAMSYGLWLTTFGAKFAESYMYLTLSFRDPIRYLSIMKVQCQGDKMFGDVLCKHQPAITLGLMTFTDLIFFFLDTYLFYVLVNTVFSIARSFYLGSSIWTPWRNIYSRLPKRIYSKVLATTDMEIKYKPKVLISQIWNAIVISMYREHLLAIDHVQKLLYHQVPSEQEGKRTLRAPTFFVSQEDHSFRTEYFPSHSEAERRISFFAQSLSTPIPEPLPVDNMPTFTVFIPHYSEKILLSLREIIREDEPYSRVTLLEYLKQLHPHEWDCFVKDTKILADETSIMDSNNEKSEKDTAKSKIDDLPFYFLGFKSSAPEYTLRTRIWASLRSQTLYRTISGFMNYSRAIKLLYRVENPEVVQMFGGNSDKLERELERMARRKFKLVVSMQRYAKFKKEEMENTEFLLRAYPDLQIAYLDEEPPVNEGDEPRLYSALIDGHCEVMENGIRRPKFRVQLSGNPILGDGKSDNQNHAVIFYRGEYMQLIDANQDNYLEECLKIRSVLAEFEEMKLENTSPYTPGVKNEVTSPVAILGAREYIFSENIGIMGDVAAGKEQTFGTLSARTLAQIGGKLHYGHPDFLNGIFMCTRGGVSKAQKGLHLNEDIYAGMNAMLRGGRIKHCEYYQCGKGRDLGFGSILNFTTKIGTGMGEQMLSREYYYLGTQLPLDRFLSFFYAHPGFHLNNMFIMLSVQLFMIVLLNLGALRHETIACDYNRNVPITDALYPTGCANTDAVADWVYRSIISIVFVFFLSFVPLATQELIERGAWRCCLRLLKQFCSLSPLFEVFTCQIYANAVQQNLSFGGARYIGTGRGFATARIPFGVLYSRFAAPSIYFGARLVLMLLFATSTVWTPALVYFWLSLLALCISPFLYNPHQFAWNDFFIDYRDYLRWLSRGNSRSHASSWISFCRLSRTRITGYKRKILGDPSSKLSADVPRAAMGNLFFGEIFAPLVLVAITVVPYLYINAQTGVAEDASDTDGPTNAVIRLGIVAVLPIVVNMGALFMMFFMACFMGPLLSMCCKKFGSVLAGIAHGISVIILIVTFEVMFILEDFNWARTVIGMIAAMAVQRFIVKLIISLALTREMKTDQSNIAFWSGKWYSMGWHSISQPAREFLCKITELTLFGADFFLGHFILIFMFPFLMVPKMDTIHSTMLFWMRPSRQMRPPIYSLKQSKLRRRRVTRYATLYFFMLVVIVAVIVGPVVIGKLDIIKTDSLPSLLKTNRLIQYNKQDNDNTRGKLITGVRNPTYTGKGLSTVTDNAATAEVTETAGAKIKIKLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF64</accession>
    <name>A0ABR3ZF64_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Golgi apyrase</fullName>
            <ecNumber evidence="6">3.6.1.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">YND1</name>
        <name evidence="6" type="ORF">Cpir12675_001664</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GDA1/CD39 NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.5" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000027">
        <property type="protein sequence ID" value="KAL1899004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004050">
        <property type="term" value="F:apyrase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd24039">
        <property type="entry name" value="ASKHA_NBD_YND1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.150">
        <property type="entry name" value="Exopolyphosphatase. Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000407">
        <property type="entry name" value="GDA1_CD39_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11782">
        <property type="entry name" value="ADENOSINE/GUANOSINE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11782:SF121">
        <property type="entry name" value="NUCLEOSIDE-DIPHOSPHATASE MIG-23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01150">
        <property type="entry name" value="GDA1_CD39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01238">
        <property type="entry name" value="GDA1_CD39_NTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="497"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="571"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="571"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="587"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="602"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="643"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="655" mass="72478" checksum="770339FF22F79895" modified="2025-10-08" version="1">MGKHSRYGVIFDAGSSGTRVYVYKWKDAHKEIEEARKNHMNILPKIKIEESKKVHPGVSSFAETPTRIGPDHLKALVDVALSEIPKEKVPGTQVYLMATAGMRLLPEAQQKTLLSEVCSYFQKHTEFSIGDCTTQFQVIPGETEGLYGWIAANYLLGGFNPKENAGTNSHNTYGFLDMGGASAQIAFAPNATEAEKHANDLKLVRFRTLDGNPLEYKVFTTTWLGFGANKARDRYIEQLVSKYEDHPDGLPDPCLPKGLRMTPTGQILNSDKSKPSGAILLGTGDFKNCLAETQPLLEKDAPCLDQPCLINGQHVPAIDFDVNHFVGVSEYWHTTHGVFGTHDDDKDEYDFTTYQDKVNQFCSQDWADIESLLQDRSKSIDEKAQDALQACFKASWLINVLYEGIGIPRVGLEQSPHNLSIDHFQPVNKIDGAEVSWTMGKMLLYASGQIPASDPSALPVGFGSNEAGIPTDFEYAGSVENEAPNDKNNLVQPPSQSFSSILLFILVIITLLLCLRKRDYRARIFAFCQGLFSNNRLSSPRKALGPGTSFIRRLLRTNSVPYERVLEEADPDDFELADTDGNDSDASVSSLSRGPSSLPRINLERQEGSPAARIDRRGMVVRTESREQLALPQMLNAGRRSRTGSPTRNKSPLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGN3</accession>
    <name>A0ABR3ZGN3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Calcium channel YVC1-like C-terminal transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_001522</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000024">
        <property type="protein sequence ID" value="KAL1899324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052971">
        <property type="entry name" value="TRP_calcium_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056336">
        <property type="entry name" value="YVC1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35859:SF4">
        <property type="entry name" value="MEMBRANE CHANNEL PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G11300)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35859">
        <property type="entry name" value="NONSELECTIVE CATION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23317">
        <property type="entry name" value="YVC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium channel YVC1-like C-terminal transmembrane" evidence="3">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="586"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="296"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="351"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="593"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1899324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="629" mass="70229" checksum="B39F37F8651D324D" modified="2025-10-08" version="1">MAIASNATEEHQFLFAINTISMVKNDSLFSYIPPGNIFAWLLMPLRYLMPLRHFVWLNRLIIKVTHFPILWAIFVYERYFLAMSIYEPTDLVDHPGVSRGRTISIADPAGRIAAFSPNVRVREESVVGYQKDRALEEVFRRPPNYHTLRNQRRNERRRNQTEIRNWMDRNDATGPGTWQASAGASENNWMRRYSMTQNTLHRVSDVRSTASDPADRLSNSGFIRRHSGGGPSPLHKRHNQQDYKDHTDGGDGDDELITNDEGDDEDIVINTVKQSFHNNAQAESEYTTEEEDAYFPTPTAAKSSAAWPSSPRSNQTRKGLHNRTLSTSTIMFNPKQYGNGTMIQEFKQKDGSAQQQAGGSGISISIPTTTKRSSDKTPRLSPPARPIAMCKSPGTAGPSRPIFTQDLESGGGRGRRLSSIDAAMSESQILPDDDDENDDIVDDDIIGGLSSSFQTQMAMALKHGRRFDSMARQRDNSDRDRMSRLVLARMKTLEESFAQVMHEMRELKVLSTSSTNTAPPTRHNSVVNLVPLGKPSHNSKKHNEAKVRNKVRGRDQSGSLMAGSGQRRAAPVRRLVNGRSLGLKGVKANDGAAEERTTEEKKDADMQGNRKGKTMVISSESDIAEAQEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGR0</accession>
    <name>A0ABR3ZGR0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">1-phosphatidylinositol 4-kinase</fullName>
            <ecNumber evidence="2">2.7.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">STT4</name>
        <name evidence="8" type="ORF">Cpir12675_001423</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.67" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000022">
        <property type="protein sequence ID" value="KAL1899387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004430">
        <property type="term" value="F:1-phosphatidylinositol 4-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05167">
        <property type="entry name" value="PI4Kc_III_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.70">
        <property type="entry name" value="Phosphatidylinositol 3-kinase, accessory domain (PIK)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015433">
        <property type="entry name" value="PI3/4_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001263">
        <property type="entry name" value="PI3K_accessory_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042236">
        <property type="entry name" value="PI3K_accessory_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045495">
        <property type="entry name" value="PI4K_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048:SF15">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00613">
        <property type="entry name" value="PI3Ka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19274">
        <property type="entry name" value="PI4K_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00145">
        <property type="entry name" value="PI3Ka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51545">
        <property type="entry name" value="PIK_HELICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIK helical" evidence="7">
        <location>
            <begin position="1393"/>
            <end position="1580"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="6">
        <location>
            <begin position="1700"/>
            <end position="1983"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="479"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1899387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1999" mass="221164" checksum="7B44884A4A3F3057" modified="2025-10-08" version="1">MARDFRQRALDKIASLAATSSYPSFDRSDFDRLCSACSTATRAKDAANGFVPNTRSVAGAPAPMARVPMTICEFQVLVSLCKAAPNIRSVQNAQRLAYQLAPYIQEAHMQLFAPSPYFRKVEPSPSESLTFHVSAALLHLGKAFPELQDKISDNLWAYLASCAAAAEKIEPPQDDDEPNLDDAMHTATIAVSLLGFLDAVASQPDFWTPASRLSLVQNVRRLLSDRFLVAMETAFSTLRVAPTGHRTVKEWKRYLKHYTLSGRPLSSMLVQRSFTWLLISVTSLLIVPANQLRGSHILDVLMSGKELPEPVAVSTGDANTDTISVYTKMATASMLYFEAGADFVVQLGSSLQQRLAFSVKSAALIAYVNCAVLNDDAADPDTMMAWLEEILADPVQMTDELLASTVLRGLAVLCRLSPDYALGVSRLLPRFIIQSSPNQNIIALASHSLAYVLQILSKDAVITTLYSLGNVLSPASERPRAKELANGTGPVAVSGSETAPEPASGYGALYNEGVTTGSFMSLSGDAAEEAGVVHANVVQAICGIAQDCNDEKITALAQSMLLQKFGKVNSQVDAQLIAAAGALALKSGVLEFRSLLKMYARISHQGVSENSENLLDAVMKARTYLSTHLNRDSPLYGIYWEYLLDSVIALGDVSRQDHTKEADVQLAAREIAQLLKPLAVFMSTSNPALATAEGDKSSGLLRDAWFNITVYGFLPSTDRGKAHLADLRTIALHSPPLVAEQPGEKIESDIELNTVLRRAMSSEREAIQKKSLSELLPSRASEIRGLSYRKVIFLQAVYLVESLRADAGDCTKALSYFVEPSMRKGDLSGPMDVIAATVVDKYLHKTLQAADPAFSAQYVAYQLASIFSSCCHRVERVQQAAFACADRILNDVPSALCYRSSLFALLELLSLMWTGCLEAETDVYDPRSVFTSSLGKVTIELSQNYTHRRSTMDLLYRKAKTWVTAALTLAPADVKGLLQTYLSEYDDAGAYGHISLGRSFALEMGSLLPSTDQRLQAMDRIGDISVNTASDFIAQYTTRQEYRFGETLPTRGTELLSYMRANNKHESFMLGKGPEAATSLNESASAATALQHIEARILSRKPTPLSEVREILRRAAALLCRSPHDETAAAHHLVSIPFAMFTRRSLKLGVSLWLGVVNENPRLEPRLLNEISHHWEATVHKKQGMFNPALAHPDPFFLRCDFSPTDLEALAKRKQLVHNLLSPHTSLLQFFTSHFNATRLGSPDTQRIFLRLLDTTLDALRHTSAHPLARDLRFQIVLFGLRVLRLSSTIGAVAQWRLKDKILSAALGWFRFAPRWSFGSNLLQMKTELRLLSDVITALKAVNSIGVQGTNNIRSLQAKEQLLNLLLESELQRLAVWVYPLPDSAKHAGIASARARNTIEAELIPLVRTAWSQDPSIAIELVSRFNWPRIHKEVRWLLLNVPSNAINEPEALAVLFGGKLPEDVTFLQLKHLLFWAPVNPLTAVTLFLPEYKNNPFVMQYAMRALESHPINVTFFYVPQIVQTLRYDTLGYVERYILETAQFSQLFAHQIIWNMKANAYKDDDGQIPDELKPTLDSIMNKMVTSFSIEDRVFYEREFAFFDEVTGVSGKLKPFIKSSREIKKQKIEEELRKIKVEVGVYLPSNPDGVVIGIDRKSGKPLQSHAKAPYLATFRVQKRDVDDGGDDLMQLPLDDSDPAPGGGADVTIALNNNTAPKANSVSEANSIVPPNAVVATVSAPMEVWQSCIFKVGDDCRQDVLALQMIAAFRGIFNSVGLDVFVYPYRVIATAPGCGVIEVLPNSISRDMLGREAVNKLYDYFVSKYGNEDSLRFQAARANFVKSMAAYSVISFLLQFKDRHNGNIMIDDQGHILHIDFGFCFDIAPGGIKFERAPFKLTTEMMAVMGGSPDHQAFRWFEELCVKAFLAARPYAHKLAEIVHLMMDSGLPCFKPESVKHFVDRFVLDKSEKEAADFMRDLIHKSYASYSTGIYDHFQLLTNGIPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHQ5</accession>
    <name>A0ABR3ZHQ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein transport protein S9 plasma membrane t-SNARE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SEC9</name>
        <name evidence="4" type="ORF">Cpir12675_001302</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000019">
        <property type="protein sequence ID" value="KAL1899717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="3">
        <location>
            <begin position="350"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="297"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="388"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="228"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="74"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="108"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="124"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="165"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="297"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1899717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="415" mass="46371" checksum="C40235DD2330A0C9" modified="2025-10-08" version="1">MRKLFKKGDKDKGASAPAENPYAAAPKSNYAPSVTSIASAAPSYRTQDPNPSRPMGGQSAPRNNSYGGMPPPQQQRQQPQQQYTSTTYGSSSGYGSSQYGTPAGGHYNNASRGQGSYGNSHISDQTHDVNRAHLMDGAKPVGSSYGGFQSNPYATNAAPPDPQNPYANPNDMQQQQQPRGRYFDLTQEEDPDDREHKDVANQFLEEKAQTNNTLDRIIQLTAGIEMQSDDISQRIERQEASLDNYERNMDIANAKTRQAKAAVKDLSTADQMFNFRTRGKREREVAEKTERDLVARQVEDKTRNSRHERQRTFQNAMESQPKPRSTFERNTGKNKLAFDFDDDGFQAENDGLDNEFDDKMDVVERSIGVINMRAKGIGFQIEQSNQRLPGLTEKTDSAIGTLQDTNHRLRQKMGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIE8</accession>
    <name>A0ABR3ZIE8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">U3 snoRNP protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">UTP6</name>
        <name evidence="8" type="ORF">Cpir12675_001507</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UTP6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000024">
        <property type="protein sequence ID" value="KAL1899314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013949">
        <property type="entry name" value="Utp6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055347">
        <property type="entry name" value="UTP6_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23271">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN 66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23271:SF1">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 6 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08640">
        <property type="entry name" value="U3_assoc_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 6 N-terminal" evidence="7">
        <location>
            <begin position="12"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="204"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="206"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="224"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1899314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="400" mass="44828" checksum="33F9727154656BEA" modified="2025-10-08" version="1">MAGVSEKARFYLEKAVPQLREWEDKSIFTKDEIRTIVQKRSDFEHRVLSPGNTPSDYLEYADWEKTLDSLRIKRCQRLKIRNLSSAHTAQVKLLSIYDRGVGRHPGHRSLWIAYLDYAASIKATKRWRLTVTRALRMRPTDAGLWIMAANKMAGHGDMASARRFYMRACRFCVYDGTVWAEYARCEMVWLAKLALKNNNKGAKPIDSVKPDQVDENDRISLGGSDDESDSDDDEIVRADPSGKAAAIFSTEAKQELTNPALDGALPLAIFKIARNQKFWDANAAELFFNVFTSFPGLPAHENLVQAVMDSLDESFPQSPVTLICQIRRPVAGISPLTADFPRGLREVVPLLKEALVTASDKKAFGEKATQWLDGLLATKGLDADIAKVLEYLKSLVMTVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIF0</accession>
    <name>A0ABR3ZIF0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_001083</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000015">
        <property type="protein sequence ID" value="KAL1900082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF210">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="4">
        <location>
            <begin position="293"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1900082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="614" mass="65935" checksum="92E3986D4BAD1EFC" modified="2025-10-08" version="1">MSASSPTYQPSFDYVIVGGGTAGVAVAARLSEDPNVSVLVVEAGDDRTQDPLVLTPGLVAGLYGKDEYDWNFMSPPQASLQSSESLNGRVINQARGRMLGGSSALNFTMAVYPSKRSIDSWANLGNDGWDFDHLAPYLRKFASTSDPGEAAVETIRCESYYDGEISEKEAGPVKLAYSNGYGRMNSAWMDVFERLDLKMTSDPRSGTAIGAFQQPATINPETRERMFSANSYLTPEVRARPNLTVMTNSLVSKVVLDKGEDRGEAVATGVMIRGASGHVTEVKASKEVILAAGTLQSPQILELSGIGGKGLLDKHNITVIVDNPNVGERVQDHPIVCQSMEVVDGINSSDVLRDPVILGAAMATFQDGGKGPLGESIISTAFVPAANENGLLPVETRKEILDKYVTGSDPTYAEIRSIIESEKEPAYQMIAFPGQTNMSPKPASLLDIITPAQPETCVTIMTILNHPFSRGTCHIVSPDVAVKPEWDPRYNSNPADMEILARGVQFARNLMTVEPLRSIFKAGGKCLPNITGNSLEDAKEVVSQRQISVFHVSGSCAMMPREKGGVVDSKLRVYGTKNLRVVDASVFPVVPLGNIQTTVYAVAEKAADIIKLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIH9</accession>
    <name>A0ABR3ZIH9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methylated-DNA--protein-cysteine methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.63</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">6-O-methylguanine-DNA methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">O-6-methylguanine-DNA-alkyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Cpir12675_001175</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 4-O-methyl-thymidine in DNA + L-cysteinyl-[protein] = a thymidine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:53428"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:13555"/>
            <dbReference type="Rhea" id="RHEA-COMP:13556"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:137386"/>
            <dbReference type="ChEBI" id="CHEBI:137387"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 6-O-methyl-2'-deoxyguanosine in DNA + L-cysteinyl-[protein] = S-methyl-L-cysteinyl-[protein] + a 2'-deoxyguanosine in DNA</text>
            <dbReference type="Rhea" id="RHEA:24000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:11367"/>
            <dbReference type="Rhea" id="RHEA-COMP:11368"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:85445"/>
            <dbReference type="ChEBI" id="CHEBI:85448"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MGMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.63" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000017">
        <property type="protein sequence ID" value="KAL1899954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001497">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00589">
        <property type="entry name" value="ogt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10815">
        <property type="entry name" value="METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10815:SF13">
        <property type="entry name" value="METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="Methylated DNA-protein cysteine methyltransferase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00374">
        <property type="entry name" value="MGMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding" evidence="12">
        <location>
            <begin position="61"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1899954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="165" mass="18356" checksum="6F80C3A763669726" modified="2025-10-08" version="1">MITKTQQPGMKASGEHIVTLINNPQSDPINKIDPPMRPPPLLLTQDKIYLNKINSCNRSVFEKNVLRLLLQIPCGCYTTYGQLAGALHSSPRAVGNALRRNPFSPQVPCHRVVATQRSIGGFKGVVGEETDKVREKRVLLKREGVKFDGRGRVLGSPFEGWRQLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIX2</accession>
    <name>A0ABR3ZIX2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RSE1/DDB1/CPSF1 first beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001116</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="1">
        <location>
            <begin position="55"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1347" mass="150947" checksum="96ADAEAD1969D2B0" modified="2025-10-08" version="1">MSFFQIKTLKNGEWVHQDVKLEPFSGYKPAPHHFPADSRHPQLGMLSRTVISTPVIRSIVPARIRSPAHNDIVFIGDRFIRVCELRKDDQLYEIARKTDFEPRIIHSRVIGYNYEPETMATHGTGDSELPISAILDENAVDRGDLPLQILVLFLETHEYVFVFMGSRNGKPEFVCSQSAGPRNEMMQDPGLHFAIDPESRYMATAFSKSGFCVSELEPYETLRQQYREGRSLNPIRSWKSKMTNGYVVKMDFLHPRDEDPESVILLLVLNVDGSTRIMTYEWRNGNNLHEVLRSRRKGYLVFPSHEMPMHIVPLTVKSSFCLITETSLAVCDDILHGNPTFQSIEHDYKEPTPWYHGTDRPLWTSWARPYRRKSYYSRQDNIYVAREDGIVVWLEFRPGEIMATSLEMGDTHLSTSIDTAFTTVSNGFNDLLIIGGDCGNGSIWKAPPRRDLTWIGNLPNWTPCLDIASNDEFSTWNQKLGSKGKPMSPWFSMEPDQLDIRVPDRLFATSGRGINGGITEHRIGIPANIGIEFDYTAVREAWVLPQLFKMSSTSSQASPPLLMLLSQHDSSDVLLFSLDSDGEIEVQQLDSEDTFLDMTYQTLDASYDQHTNLCQITEKSIAFCTVDDSRVVSLDEILGSKDLKAEHASIGFGLIGVAAHLDAAYKLFLLEIDGTNAVLRGGASVPAEITCLRVCQIENSRLILAGLQRDGLVTSLAIYDADSFGPESTPVSEFSIVSAASSSDEVSSSPHCIEAFSSIKKLCETETSVVIIGGTRAGYIAIMSLSRGTLECKLLSVRRLGLLPVSLSLMPNDDMGNSIIASSGTSLISLNDYREDHSGRGEFKDVSYILPGDSRDSMRTLPAVHCVSVLPKGVPAQNSSSISVLMVTSKGVHIAELEKKARPVPRLIPIPGAPKRVLFSHTLDCLVVSTFFENRPTLLFIDANTGEDLSIPSSRTGNVWPFISGLGEDGDRILCIKEWLYTKDNNQFLFFLVCLKSQKMLIVSTLPIQDSTKVGNRAIKYWTTHKIRGDEDSVYCAHASRQNLYYSSGNNLNWAYLDNEDKKFKNKATFRLSSPVISIEDYGEDIIVMTAMQSMLVLSPKEGENGVGFFQILNTDPKPLMGNGIMAIGSDDSTTSPFPLMLLGDREQTVAGRWIPKSAGAEIEHMFEGMMKGSIRKFCRARSQPNWWFKQTGPRFGRIPSTLDDAEVFGIALDGTVEHFALLDMDGWRFLSLVEKMAKYTPEICPFNYGDRRQIQQLSVSELMPLAAIPASMHINGNILQRILDSKALERCFFTSVSRELLQRLLENLDEGHWVSHIQSEQDPMKREVLCFELAYTILEYYLRAVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ55</accession>
    <name>A0ABR3ZJ55_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PQ loop repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_000875</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051415">
        <property type="entry name" value="LAAT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201:SF37">
        <property type="entry name" value="PQ-LOOP REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="190"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1900738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="287" mass="31600" checksum="6AC151604BE1D727" modified="2025-10-08" version="1">MDVPAASNVLGTLGAVCWSIQLIPQIVINYRRHHTTGLQPAMMMLWAWAGVPLGVYNIVEDFNLALKIQPQILTVLSLVTWTQCFYYQRVSNWSILRSLMLVTPIAALMGGIEAALIIALRIAKDGHVEWPLTLMAVASAVLLALGVLSHYVDIWRHRTVRGISFIFVGIDAAGDIFSLLSVLFQSKADVLGIVIYASEFVLWCGVFACGGWYNLRPWIKKKLSNYRMREKSAAPSNACATAPETIEGPGANTLTLHDMPSSTSVFTTTGTAMELRERRHSASIHSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKF7</accession>
    <name>A0ABR3ZKF7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CENP-T/Histone H4 histone fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_000864</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22920">
        <property type="entry name" value="HFD_CENP-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035425">
        <property type="entry name" value="CENP-T/H4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22980:SF5">
        <property type="entry name" value="CENP-T_HISTONE H4 HISTONE FOLD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22980">
        <property type="entry name" value="CORTISTATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15511">
        <property type="entry name" value="CENP-T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CENP-T/Histone H4 histone fold" evidence="6">
        <location>
            <begin position="385"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="106"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="292"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="124"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF15511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1900727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="514" mass="57201" checksum="B77C4B3B318C91A3" modified="2025-10-08" version="1">MSSPGSSPPPTTRVALATPARPTGNSTARAVRTPLDKTAPRDLLNSVRRGQSSVRNRIATNAPTPHARAAIRALDMRRAAVFTPGKGRRKSVRDQRETPRDILRMLSRSLAPVSRAVHTSSSSSDKKSPERSMVGDETDISNGMDYDEDDDDDVLMRRPEFTLPLDEGDEEDDLVAPRSMLLEDETMGNLTMQSMEFPRRATNDILVDRRLSRMSMGSMRFSDVGLQPHQLGSDDVAVDSGFFPRIDLDDIPDQTAGDLTMQRIDDTTRHDITSGNGDLSVPEQESLFVELRSQSPDSPEPFGDISQLQNLEPEPEPEPTQHDISMEDDGAGVSAGDRQFLPLMQLESEDDDQGEIEDIPDITFDSRMKEQQREARKKGIKLSAYGTEYPSIPPSVVKRLALMFAQRSGLGKCKISPGTLQQLSLATDWFFEQVGSDLKAYAEHANRKTIDESDIALLMRRQRQISSTSTLFSQAHKYLPRELLQEIRMPAALKMKKSKVVNDVTEETDGDNQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLU0</accession>
    <name>A0ABR3ZLU0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH:ubiquinone oxidoreductase intermediate-associated protein 30 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_000573</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CIA30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013857">
        <property type="entry name" value="NADH-UbQ_OxRdtase-assoc_prot30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039131">
        <property type="entry name" value="NDUFAF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13194">
        <property type="entry name" value="COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13194:SF18">
        <property type="entry name" value="COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08547">
        <property type="entry name" value="CIA30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:ubiquinone oxidoreductase intermediate-associated protein 30" evidence="5">
        <location>
            <begin position="44"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1901207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="261" mass="30314" checksum="244C5A5174C8C817" modified="2025-10-08" version="1">MRNTAALLAKGFWGRTMAHIQRQVQIVTKMENIRGPSGPYELQKFEGPDDVEDIKLMSDQEFGGFSTSNSEYISTREDSNGRSDRGYMRWYGTISNQLPKDRFKVKRSGFAAFRTCDQKLTAFGYGKWDVDPWNYLALRIKSDGRSYFINIMTESIVPQDVFQHRLFAKRPGEWETVLIDWRDFMRTNHGMVIEPQIQLIKQRVLTVGISLIDRKPGPFELCVERIWATNSLRDHTTDERRALSSNGLKNKQGEDVTWKMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM76</accession>
    <name>A0ABR3ZM76_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Serine/threonine-protein kinase</fullName>
            <ecNumber evidence="11">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">YPK2</name>
        <name evidence="11" type="ORF">Cpir12675_000438</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="11"/>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd11651">
        <property type="entry name" value="YPK1_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="269"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="10">
        <location>
            <begin position="527"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="88"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="586"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="88"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1901569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="612" mass="68226" checksum="99971220C4B7C34C" modified="2025-10-08" version="1">MSSWKLTKKLKDTHRSPFSGFSKSSSSVNDEKEDEAAVPAPELANPSAVSSEALTQAPVIKKPGILIITLHEARGLSLPDQYQHVFATQHSSSSRSTGNALSATSGSVRNTPSAGSLHSDRPSSQGRGGFKGLPTTHGRVSGKYMPYALVDFEKVQVFISSVDGSPENPLWAGSNTQYKFDVSRVSELTVHLFVRNPNSKPGSGRDDDIFLGAVRLNPLFESLDTGVSKNDEKGFGGVNWVDIQHGTGKLQIGVRFVENQASKLSIDDFDLLKVVGKGSFGKVMQVRKKDTNRIYALKTIRKAKIISRSEVAHTLAERSVLAQINNPFIIPLKFTFQSPEKLYFVLAFVNGGELFHHLTKEGRFDINRARFYTAELLCALECLHGFNVIYRDLKPENILLDYQGHIALCDFGLCKLEMKDEDRTNTFCGTPEYLAPELLLGKGYNKTVDWWTLGVLLYEMLTGLPPFYDETTNEMYRKILSEPLHFPSSDVVPPAAKDLLIKLLNRNPDERLGARGSTEIKSHPFFHAIDWRKLLQRKYEPTFKPRVTSALDTANFDNEFTDELPQDSYVDEPTLSSTMQQQFDGFSYNRPVAGLDDAGGSIRDPQSYLPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM99</accession>
    <name>A0ABR3ZM99_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_000295</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1901786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="218" mass="23451" checksum="42A4AB4A252BE3CE" modified="2025-10-08" version="1">MTCINIQSSAQWDTILKTHNVVVADFYADWCSPCKMIAPKFESLAREYSQPKKVAFVKVNVDIQRDVASSQSVRAMPTFKLFHRGQVLDTVQGANPSALAAAVASALLLKDKGTPGEVFGTPGTRLGGAGLDDDKHTGGRAESSLARLSPVGLLSNIFMMVGLYFVSLLSLDPYKSAQMSRFNTVNPPEIVTVKTQAADGSTVTKKVVRPAFKTLADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN14</accession>
    <name>A0ABR3ZN14_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Large ribosomal subunit protein bL21m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_000147</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028909">
        <property type="entry name" value="bL21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036164">
        <property type="entry name" value="bL21-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL21M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00829">
        <property type="entry name" value="Ribosomal_L21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141091">
        <property type="entry name" value="L21p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00044129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="199" mass="21996" checksum="9FE3ECAD7A8597B8" modified="2025-10-08" version="1">MSRTLLRSIAGLRATVTPRFGLPCPVLAQPFTAVRRFNSTTPIVESTTTTTTTTSTSASSSLTTPQHSKAISESVRSLLPVLAAQPSHYITIHIHGWPFLVTKGDSVRLPFRMPGGEPGDELKLNCASVLGSRDLTLKGSPYIDERLFECRAIVVGEEAEPMREKIKTTRRNRKTKKAKSKHRYTILRISDLKINEVPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN46</accession>
    <name>A0ABR3ZN46_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">alkaline phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_000443</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the alkaline phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.1" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16012">
        <property type="entry name" value="ALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001952">
        <property type="entry name" value="Alkaline_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596">
        <property type="entry name" value="ALKALINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596:SF72">
        <property type="entry name" value="ALKALINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00245">
        <property type="entry name" value="Alk_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00113">
        <property type="entry name" value="ALKPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00098">
        <property type="entry name" value="alkPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047365012" description="alkaline phosphatase" evidence="3">
        <location>
            <begin position="19"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="678" mass="75269" checksum="C705E71BBEFFF86D" modified="2025-10-08" version="1">MAKLTSFALLASASLGAAQTYQRLGTCPKLGCILPPDQADFLPGQYFDLRVEVHAPVNGTEAFNDGVPDEAFTATIRKVGEDMARPISEFFTMEEPELENWEFGWYEDRFAEDIKSKSMVNVASKIYRRIRINEPGEYEVVLTYYNDRTTVAKWEVRPISSDRKAKNVILFIGDGMTTNMITAARMLGHESINGKYQSRMAMDSFPVLGHQMTHSVDSYLTDSANSASALYSGHKGTVDSMGVYSDSSPNQFDDPKIETLVELITRILGMHWGAATTAHLPDATPGALVGHTRSRANFGSLLDQTLNGVTNYTWNDYVGPEVFFGGGAEAFFDSDVSYLGQDYYNEFANKGYKISWNKTSLVDLNSDSRALGVFSTGPMPVWLDRNVYPENLAKLRNHPSGQKIPALDVPGLKEMTSKAIEITHARSKEKGKDKGFFLMIEAASIDKQMHELDYYRALGDLLELDDTIKETLEQLKEMGILDETQIVVTADHGHGFDVFGSADTKYMDAADNDRKKRNAIGIYGQSGESQYTKSVPGISYGTGPNFPMNWEPRYAMAAGMAAGPDRREDYRVRKEGRRFPTIKTYDADGKIEAYANPEDAIRGIIINGTIASHEPSGVHSITDVPVFSRGPCQNDFGGVYNNVDVFYKIAQCLGLGTKRTENGQEYSQRATRRAADRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNA5</accession>
    <name>A0ABR3ZNA5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Subunit of TIM23 translocase complex</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MGR2</name>
        <name evidence="7" type="ORF">Cpir12675_000029</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MGR2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018450">
        <property type="entry name" value="Romo1/Mgr2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28525">
        <property type="entry name" value="REACTIVE OXYGEN SPECIES MODULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28525:SF1">
        <property type="entry name" value="REACTIVE OXYGEN SPECIES MODULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10247">
        <property type="entry name" value="Romo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01378">
        <property type="entry name" value="Romo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1902131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="92" mass="9983" checksum="1E9FF5CBED39E84E" modified="2025-10-08" version="1">MGAITGGSVGAILGFLYGTLHIFRYGAGSSGIMRTLGQYMAGSGATFGFFMSVGSVVRSDTQTSELTQAYMRTQRQPYLVARRDFREQALKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNN0</accession>
    <name>A0ABR3ZNN0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Exocyst complex component 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SEC10</name>
        <name evidence="8" type="ORF">Cpir12675_000278</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEC10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009976">
        <property type="entry name" value="Sec10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048627">
        <property type="entry name" value="Sec10_HB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048625">
        <property type="entry name" value="Sec10_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12100:SF0">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12100">
        <property type="entry name" value="SEC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07393">
        <property type="entry name" value="Sec10_HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20667">
        <property type="entry name" value="Sec10_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component Sec10 N-terminal" evidence="7">
        <location>
            <begin position="64"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Exocyst complex component Sec10-like alpha-helical bundle" evidence="6">
        <location>
            <begin position="203"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="859" mass="95343" checksum="780B22FCCC23BD1B" modified="2025-10-08" version="1">MAVDRAGGPGTKSLFPKGPSFSLDDFSSKDFIVRDFIDDLADSAAPANRGSGGAQPTRQSSFDPKPLIRTFENAVSQLEDLSGTLQDRESELLSQVRRAEIQHDQTLDTLGHKLDQSIETFEALDINSNGSGGNPSGFSNNASDMGGIVAVQIGERLEELDRKRRRAKDAIFLIQCWQEVGETGSLISLQGMQRHGGSDNKIRCAVIAKQLMRISQRLDPASWSSSGSRANALLNGSMPGGPGVSNVRHNTREVLEKFSEGLEQELLTQFNNSYRRQNFDDMRECAKVLKDFNDGASVIAIFVNQHQFFIDRDQLMGDEVTADSDSWDKVADPDAEPPSVEPSLQSLLDEVRIVMQEESFIIKRAFPYYETVLIKFIQRVFQQSIQLRLELVLDKATSISSLAFLRVLHSSRTYLNTLIDDLKQHGLTEHPEPCSAQVAATLDQQIEELCVPYLMGNGYIERERKSLEELYNSLLFKYTTYHSRRQRRPTGFIATLAQQGTQIIASAKDAYLERLESSDLTATQKAMMLRVAGITEVNKNDVELLEEDGVLGVEYAKRMLTWLAESVRRALELGSVSDTPKDANILMNLLLTSMGRVYIETALDAAADHATSLENSKTEPDMTYLTNLRPAITITSMMDRFISIVLIRLADGNATMRRNMDAQKRTSLDALEKKTNGVLKTTVDVVANYVSKALNMQKKLDFRPRDGDDLDSLQTQACQVICTFLARVSSSAEKAVDGSNLEHFSCEAAMAVCRLLFEHFKKFQVNATGGLMITQDIAKYMGTIKTWALTRDVEMVVEMLSEVGSLFIVGPEALREKARTLTAGPPGLGKRLTKADFKAFVQRRDDSGSVEIQGVLSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP48</accession>
    <name>A0ABR3ZP48_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_000512</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WHI5/NRM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013734">
        <property type="entry name" value="TF_Nrm1/Whi5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08528">
        <property type="entry name" value="Whi5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="198"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="198"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="224"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="268"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="320"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1901279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="362" mass="39131" checksum="469F8C8DABA01469" modified="2025-10-08" version="1">METPSKRRALGLLDANVNASPRSPIKSLKTPASDIRKRPFDNIPSLPIPSKRACLHNMPTAANGLQPSPILSKFSLNDTELDLPPASLSMGLGMTSFDSSPDASRAFMTACASSPTVSLPRPRSRTMSRQETRQKADALRLRLGLANYKLRTGQADVPLDKLQMRPCRLLRHSISFPNPRSPPTFAAMAATARKALGHMSTSTSAMMSSSPVQPSPLRERQHRVATAATAPDVTATTPPRASVIAPRQIQLPTPMPSQEERQERQRQLQKQKQQLQLLRQTPLKIPKVELTGDETESEPEPDAEEEGEGEEGGDGHDADNAGDETETEPELVVTPKKQIAGCSTADDDSGAATGLLFLARSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP65</accession>
    <name>A0ABR3ZP65_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_000095</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF282">
        <property type="entry name" value="WW DOMAIN-CONTAINING OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="315" mass="33560" checksum="FAA6B50AB2E54C5B" modified="2025-10-08" version="1">MPFGLNLFGGVSFNPTFDIPSLKGKVVLVTGGNVGLGKQTILELAAHEPASIWLGARDSAKAETAIAEIKTAIPTANVRHLKIDLASFDSVRAAATEFSAAESRLDILILNAGIMATPAGLTKNGYESQFGTNHMGHALLTKLLLPTLTKTAAEPNADVRVVSLSSAGHALSCYGINFDSLKSPGDSMGAYPRYGQSKLANILFARQLAVVHPQIKSVSVHPGIVRTNLMNGTTGTFWLLHRVSSLANNLFTPVDKGALNQLWAATSKDVVNGEYYTPVGVLGGGNSYANDLELAKKLWDWTEKELDAYLAKVEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPR4</accession>
    <name>A0ABR3ZPR4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpl15</name>
        <name evidence="6" type="ORF">Cpir12675_000059</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1120.10">
        <property type="entry name" value="Ribosomal protein l15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024794">
        <property type="entry name" value="Rbsml_eL15_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000439">
        <property type="entry name" value="Ribosomal_eL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020925">
        <property type="entry name" value="Ribosomal_eL15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003269">
        <property type="entry name" value="PRK04243.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847">
        <property type="entry name" value="RIBOSOMAL PROTEIN L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00827">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01384">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01194">
        <property type="entry name" value="RIBOSOMAL_L15E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="161"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="203" mass="24051" checksum="1396A83F5FE5D14F" modified="2025-10-08" version="1">MGALKYVEELQKRKQSDIIRFLLRVRCWELRQLNVIHRASRPSRPDKARRLGYKAKQGYVVYRARVRRGGRKKPVAKGATYGKPTNHGVNQLKYQRSLRATAEERVGRRCANLRVLNSYWINQDSTYKYFEVILVDPQHKAIRQDARINWICNPVHKHREARGLTSTGKRSRGLNKGHKYTKTTAGRRKTWKRHNTLSLWRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YCK4</accession>
    <name>A0ABR3YCK4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cysteine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cysteinyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Cpir12675_006894</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.16" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000409">
        <property type="protein sequence ID" value="KAL1886044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00672">
        <property type="entry name" value="CysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1910">
        <property type="entry name" value="Cysteine-tRNA ligase, C-terminal anti-codon recognition domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00041">
        <property type="entry name" value="Cys_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015803">
        <property type="entry name" value="Cys-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032678">
        <property type="entry name" value="tRNA-synt_1_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00435">
        <property type="entry name" value="cysS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890:SF3">
        <property type="entry name" value="CYSTEINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="CYSTEINYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01406">
        <property type="entry name" value="tRNA-synt_1e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00983">
        <property type="entry name" value="TRNASYNTHCYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA synthetases class I catalytic" evidence="12">
        <location>
            <begin position="48"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="715"/>
            <end position="742"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1886044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="813" mass="91333" checksum="931DF6799E5157E9" modified="2025-10-08" version="1">MASTSTARQQPPWTPPKPLAAGIKIPDLKVLNSLTRKKEDFVPLDSAGKKVSWYTCGPTVYDDAHLGHARNYVSTDIIRRIMKDYFNFNVQFVMNITDVDDKIILRGRQQYLLDNTKTEHPTIDEFVQTTTKTAFEKYILKNLPLLPADVTPGTYNAQAAATYKRVLDGLALDSDTESAGDKEAKLKMHIKTAATAAEALREASSSSLDPATFYDKAENVLLPYLDSLYGAGIDANNHSIFTKLTKKFETRFFEDMAALNVLYPDVLTRVSEYVPQIVSFIERIIKNGYAYATEDGSVYFDIAAFEKDGHHYACLEPWNRNDKSLLADGEGALSSKATTVKRNECDFALWKSSKAGEPSWKSPWGLGRPGWHIECSVMASEVLGEAMDFHSGGVDLRFPHHDNELAQSTAYWTSEHPNVQWTNYFLHTGHLSIQGMKMSKSLKNFTTIREALTREEWTQRSLRICFLIGTWQDGIEITEELIKSTTSWEDKLNNFFLKALDVERNPKTTEAAAAAIGSPETDKKLLADLEKAKTDLHTALCDSFNTPVAMRVISDLVSEFNTAKCAFAETTQQIARWITRIVTIFGLDSKNDLSDHKRVGWSGIDIPNEARSFIYPTAELRDEVRQQARSGTLDHGSISRLVDAVNAPPASGAEDKKYEGVLEQFKTDVRKLAAEKAAAKDLLMLCDQLRDTHLWNLGIYLEDRDAPLKAMVRPVDKALVAAREEREEIAAAKAAAKAKREADAAEKAQLLEEKAKLSHLDIFKTVEYAEWDAEGLPTKDAKGEEIPKSKKKKLMKEWEKQKKLHEEWLAKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFF2</accession>
    <name>A0ABR3YFF2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Programmed cell death protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006747</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PDCD5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000366">
        <property type="protein sequence ID" value="KAL1887019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.140">
        <property type="entry name" value="PDCD5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002836">
        <property type="entry name" value="PDCD5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036883">
        <property type="entry name" value="PDCD5-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10840">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10840:SF0">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01984">
        <property type="entry name" value="dsDNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015730">
        <property type="entry name" value="TFAR19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46950">
        <property type="entry name" value="Double-stranded DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="17"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="28"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="127" mass="14335" checksum="4A82DA3A0EEE977B" modified="2025-10-08" version="1">MEDAELAQIRAARMNELRAKGAASSSDAKQKSDHQRQQDIADARQSMINQILHPEAADRLGRIRLVNEARATQIEDRLMTLAQTGQLRQKVTEAELKQLLNAVSEAQEQEKIVVARKGWDLDDDLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGC9</accession>
    <name>A0ABR3YGC9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Formin-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">HOF1</name>
        <name evidence="11" type="ORF">Cpir12675_006740</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000364">
        <property type="protein sequence ID" value="KAL1887025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031160">
        <property type="entry name" value="F_BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065:SF7">
        <property type="entry name" value="NOSTRIN, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065">
        <property type="entry name" value="PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51741">
        <property type="entry name" value="F_BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="F-BAR" evidence="10">
        <location>
            <begin position="1"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="9">
        <location>
            <begin position="845"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="225"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="282"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="356"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="617"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="245"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="256"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="379"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="428"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="440"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="464"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="486"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="509"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="671"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="692"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="724"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="763"/>
            <end position="774"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1887025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="905" mass="99382" checksum="EB41EA9CE9473005" modified="2025-10-08" version="1">MGGLKISMDTLRGEVEAMAKQHQNIAAQMKSELEEPLSAFSGAMKERRKIVQNGIEKLLKTKMQQTQHVNKTRDRYEQECLKIKGYLAQGHMVMGQEERKNKAKLEKTQIALAASNSEYETAVRVLEETTARWNREWKSATDKFQDLEEERLDFTKSSLWAFANIASTVCVTDDASCEKIRLSLEQMDVEKDIVSFITERGTGQEIPDPPKYINFRRGDADITSEASEDENYSVAQFPRSINPAFRTSSPQPSTYESHHEPRAIVSEKKETQLEPFPVQLRDSSQFHSQTNSQPQQRHLAQISDTPQQAQVAIPSSGVKVTNVPQDPHPEASIVDMNGIELPLDSGSNIAHIRSFSRDSQNHDGPSNPSSIAHVESAGISPSPTKQVGQVASTSISDSENRIMKKRSGFFQSHSPFRRKSTKDKDAILQLSHSQSSKQQTMPQNQNSQSDDLQRASTGQTYGLPQQHTQQQPPQTAAQPPTDMKHNSISSRGSWNQSANQVPKQSNTYTHQTLPQAQHQQQHLPPPSRLITSGRDVSPNPIEANATLALGVGPNVLPVSANSGRNRGNSSPTKDEADPIAMALAELKDASSNTKQSSSRVSIDRYAGIATPGPGFLGNSAVQAAKRGTPPPSYDQQVQRLGAPPPAHTAKAMKEASEKFVGQTRSMFGEPNNYSSSSLPRTGTRHGARGNDGSRSTSPAPMRNSSRMGDNTRSPHRSMSPSPHTGHQQIHSNSRVSIHNHSMNKRGSDQSYYRPDTRNGPLDHSSQSRPGSSHTGGDMSMQLASPSEGDYGMQLERAGSRPVSRPGTSNSSRGVGFYDGSNQGSLRPRSKSFADPSRQYSRDGRPILHLARAMYMYQAAIPEELGFSKGDTLAILKHQDDGWWEAEVHGVGGRVGLVPSNYLQTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHB5</accession>
    <name>A0ABR3YHB5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000327">
        <property type="protein sequence ID" value="KAL1887355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="562"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="565"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="594"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="615"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="760" mass="84510" checksum="AEEC8EEEA4C32624" modified="2025-10-08" version="1">MTENELPPSYMQAVTQVHPFALIGPELPFNLIPDLIQVSKSLRRIFLPLFWRDPLTSIRRLGRDPYKDLERLEYLAKNLPTFTTSLQETISVLDLREFATKDVSLSFGDDISVTLASLVQWMPNLNSVLAGSETKFDLAPILAVVRQPRLLSFQGLAVEVAATMFSNLDASDLTYFEMSSPPGVNLNFPSLQSVRIFKLPRCKVNDEIASIVVSALSMHRKVWSIDLSYNEITDGAISQMVDHLFQDFTIRSNAYFFTEGRLINPSMKGHTNFGPFEVIQESRWSCAFNHEARYFADSPSYILEPDGNSLIRNNGKEPPLEDRLEALNTLLSKPEGDTRPYPRALTHLNLSDNNVTSLGLEKLLRISRGFLEALSCSGTQVYSSRKSVGVWKSNSSLYGVFGAAHLVRPVYSSNLRSLVIHHSLVTQIPSLVSADHSDHASLYLAEQLLLPRVQLMYPLGQYKPDMNPRLSSLTLTSVPRRSSGPLIKALVDFLDLLATQEKSIQESTKSESRRVPLMIRGLRHLRLEFEADPLSKLAKDSTSQYSDIQTLIDTTENFTFFPQDPSSSTSASASASASASASKPTAPSSQTSREAAKQAAREATRALRLGPSPNRPNSMKQPEPQSHDDRYVTFSSHWLNEDYTTKIWAGNAPSDPKAASKLSPSVRAYTQAVMNPALQKIPGPASPVQIRAGVPDGALIFHDAWEAALLPETQLLSLTEKQEKDSRAMTDVIEVLRTYRQSKTGYKWTGTVSVVFPRDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI07</accession>
    <name>A0ABR3YI07_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Gfo/Idh/MocA-like oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006409</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000295">
        <property type="protein sequence ID" value="KAL1887823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840:SF5">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="1">
        <location>
            <begin position="20"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase C-terminal" evidence="2">
        <location>
            <begin position="168"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="346" mass="37356" checksum="9256E45F7844463D" modified="2025-10-08" version="1">MSQSALPTSVYITHLPISFTKHLTAIEAIPSLELKAIYSRSQSSAQDLANTVSDSVSPHSSSLTDLPARDDISAVIICLPNIAQPAISRKAWKAGKHIISEKPIAKDVSSAKSLLKDYGILPDTKPLWAVADNYRSQKALQIAAQRLNDLGGELTFFSFEMFTLVKTNNKYFNTAWRRVPEYQGGFLLDGCVHFTASLRYSLAAVNDKIASVKASTTLLQPLLLPMDTIHGVITTAGGRSGSFNVSFGSAFRSGFCLAVSTTRGEVEMNPSEVKIVTLNSKGEKIEEVIKVTKTSGVREELKAWVNGLDIGVICTEQSPGEALRDLSVLEGLLKAGETHSSEPVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIF2</accession>
    <name>A0ABR3YIF2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">6-phosphofructo-2-kinase</fullName>
            <ecNumber evidence="5">2.7.1.105</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PFK26</name>
        <name evidence="5" type="ORF">Cpir12675_006433</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.105" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000299">
        <property type="protein sequence ID" value="KAL1887745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003873">
        <property type="term" value="F:6-phosphofructo-2-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07040">
        <property type="entry name" value="HP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003094">
        <property type="entry name" value="6Pfruct_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013079">
        <property type="entry name" value="6Phosfructo_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606:SF32">
        <property type="entry name" value="6-PHOSPHOFRUCTO-2-KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606">
        <property type="entry name" value="6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01591">
        <property type="entry name" value="6PF2K"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000709">
        <property type="entry name" value="6PFK_2-Ptase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00991">
        <property type="entry name" value="6PFRUCTKNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="6-phosphofructo-2-kinase" evidence="4">
        <location>
            <begin position="95"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="6-phosphofructo-2-kinase" evidence="4">
        <location>
            <begin position="192"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="45"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="613" mass="69228" checksum="CB5DA0A290465FA3" modified="2025-10-08" version="1">MTTSPTSLSNPPSSALGAQSVGFLPLPQNAPSSSPPQSGPESKSETPLSGMSMPSTATSSPRLQNSGSQTPRVRPHATTLNIPGMTRSKASPDGKIAERDVAAKLVIVMVGLPARGKSYITNKLQRYLSWQQHNSRIFNVGNRRRVVAGLTPATALPDAKPSRDASKVASMILGGGPVNLPHPPELNLNDPNMDQSAQFFDPSNTDAAKLREQVAMATLDELLDYLLLQGGSIGILDATNSTLKRRQMIVESIKARDDKLGILFIESICNDKDLLEANMRLKLSGPDYRDKDPNQSLEDFRRRVHAYEKAYTPLGEWEEKNDLQYIQMINVGQKIIQYRLRGFLSGGIASYLASFNLSPRQIWITRHGVSVDNEAGKLGGDSELTERGHIFGHDLYEFMTQKRKEWLYEQAARTMNSSFPPLPGDHTPPYPEINRELNEKNFCIWTSMMKRSVETAEYFEADEDYDVKNWEMLNELNAGNFEGMTYKDIEEWHPEEYKKRQNDKLNYIYPGVGGEGYLQVISRMRDMVREIERITDHLLVIGHRSVCRVLMAYFMDFTQQDIADMDVPLGMVFAIEPKPYGIQFHAYRYNEETRQFNELPDYKPQRISSKIMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIH3</accession>
    <name>A0ABR3YIH3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006464</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000305">
        <property type="protein sequence ID" value="KAL1887647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07383">
        <property type="entry name" value="MPP_Dcr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440:SF11">
        <property type="entry name" value="METALLOPHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="50"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="403" mass="45231" checksum="6AD2BAF08CDA241C" modified="2025-10-08" version="1">MFAGRFIGFNAVFLAVFAFILFYSIIQLQPTRPSFRHRSLYLRDDGSFDILVFSDLHFGEEEHGWGIAQDRKSLAIMNGILDAEDPDFVVINGDLITGENTFRENASSYVDQVVAPLVSHDIPWASTYGNHDSSYNLSREALYESESRYPLSHTQYSDKALGGVTNYHIEVLDRSGRAALILWFLDSQGGGLFQTKGNQTQTEIPGVVSNATVDWLTETHQQLIDRHGRVLPSLLFVHIPPRLFAETQTSELFAPARFPGLNKDYPLSTQHGLGLTDSRLVDVLLSLEGLHSIHSGHDHGASWCASRQRPARKIDQRDHGSDAPIFLCFARHTGQGGYGDWTRGARMLRVTVPEMTDGSRDHGHVKDKVEVESWVRLQSMQAISRVSLNETYGQDEYPLEDVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YII2</accession>
    <name>A0ABR3YII2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NYN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006359</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000287">
        <property type="protein sequence ID" value="KAL1887954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18724">
        <property type="entry name" value="PIN_LabA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="199"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="546" mass="59047" checksum="AFDF85139DA67F3D" modified="2025-10-08" version="1">MTPPISPVPATTTPLLGDFSAVQHFLQQSICQRDSKKERKERPQIRHHRSQRSHCKDPPANRASPSSSPSSRYDHPKSCLENLPVRSPPVRSPRRSPFSPASSRAVNPSLVGEDLRESFRSSPPPSHSATQRIKSRTSSGAQFDIPQDTKRHGNFGPAIANYLERLPDTPAPTPPPPYSSTLQGQAPSHTPVQPFSLPTSTSATSAATTVVPSNFPPSSTSSTTSSSSSPSASASASSSTNKSSTPPITILQHPVANVSSPPKKEKKKKLPSAEASSGVSLNMSYPSRSHTRHPGADIHISASGSLPKSAQSKTYLRSLKKSDASWATSIPSAARPLHVFVDISNIIIGCYDACKSEMGLPKNQPFPTASSFDFSAFDKVLCRSRPVARCELAGSTSKPNRWPSYAIDAKKARYDVHILNRTVTDVSKSSHSSGSKVNLGGREQCVDELLHLKMAQSVLDEELPGVMVLATGDANAAQFSDGFLMAVERALKRGWAVEVVSWSETMSHAWLDDDWCAQWKGRFRTIELDPFLAKFVGRDILRPTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ69</accession>
    <name>A0ABR3YJ69_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mitochondrial thiamine pyrophosphate carrier 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">LEU5</name>
        <name evidence="15" type="ORF">Cpir12675_006368</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000289">
        <property type="protein sequence ID" value="KAL1887922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="60"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="159"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="285"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="15"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1887922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="376" mass="40853" checksum="5C05A443C6089689" modified="2025-10-08" version="1">MPSVILNSSLAELPSNTNLTSDPQSSRHTLRSTEIPTSASTPATITAVASRKPQNKHSIDYVWRSGVAGGMAGCAAKTIVAPLDRVKILFQANSPQFAKYAGSWVGVADAMKQIHHVEGPSGLFRGHSATLLRIFPYAAIKFLAYEQIRAIIITSPEKETHLRRLVSGSLAGVTSVFFTYPLELIRVRLAFETKRDGRSTLRTICRQIHSESMAGVGTASSAIFKSGITNFYRGFAPTLIGMLPYAGVSFLTHDTMGDILRSTPLAPYTTLPRPSNAPPENKPPLRSWAELLSGGISGMVSQTSAYPLEVIRRRMQVGGAVGDGHRSSISETVAVILKERGFKGFFVGLTIGYVKVVPMVAVSFYTYERFKMWLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJS0</accession>
    <name>A0ABR3YJS0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">DNA 5'-3' helicase</fullName>
            <ecNumber evidence="17">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">RAD3</name>
        <name evidence="21" type="ORF">Cpir12675_006162</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="23">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the helicase family. RAD3/XPD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="17"/>
    <dbReference type="EMBL" id="JAWDJO010000260">
        <property type="protein sequence ID" value="KAL1888467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18788">
        <property type="entry name" value="SF2_C_XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.20">
        <property type="entry name" value="Bacterial XPD DNA helicase, FeS cluster domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010643">
        <property type="entry name" value="HBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="RAD3-like_helicase_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013020">
        <property type="entry name" value="Rad3/Chl1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001945">
        <property type="entry name" value="RAD3/XPD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042493">
        <property type="entry name" value="XPD_DNA_FeS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00604">
        <property type="entry name" value="rad3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472:SF1">
        <property type="entry name" value="GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06777">
        <property type="entry name" value="HBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00852">
        <property type="entry name" value="XRODRMPGMNTD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="19" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 21" id="KW-0347">Helicase</keyword>
    <keyword evidence="8 21" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="15" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="20">
        <location>
            <begin position="1"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="19">
        <location>
            <begin position="227"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00048954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAL1888467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="759" mass="86852" checksum="7661600EBD2FDF9B" modified="2025-10-08" version="1">MRTLDADGNCVLEMPSGTGKTVSLLSLIVAYQQNSPEPRKLIYCSRTVSEIEKALAELKNLMKYRAEQLGYEEEFRALGLTSRKNLCLHPSVKKEKSGAVVDARCRSLTASFIMDKKARGEDVDLCSYHDNLYEKDPHNLIPNGVWTFDSLLRYGEENKQCPYFTARRMFQFCNVVIYSYHYLLDPKIAERVSKEFSRDCIVVFDEAHNIDNVCIEALSTDITEESLKRATRGAANLERKVDELKATDQEKLRSEYEKLVEGLREAEEARREDGGFMSNPALPDDLLQEAVPGNIRKAEHFVAFLKRFIEYLKTRMKIRHVISETPPSFLSHLKEHTFIERKPLRFSSERLASLVRTLELTNIEDYQPLQEVAIFATLVATYEKGFVLILEPFESDSAEVPNPVLHFTCMDAAIAIRPVFERFRSVIITSGTMSPLDMYSKMLDFSTVVQESYTMTLARKSFMPMVITRGSDQASVSTGFKVRNEPSVVRNYGTILTEFAKVTPDGMVVFFPSYLYMESIISMWQGMGILDEVWKYKLILVETPDAQETSLALETYRTACCNGRGAVLLCVARGKVSEGIDFDHQYGRTVLCIGVPFQYTESRILKARLEFLRETYRIRENDFLSFDAMRHAAQCLGRVLRGKDDYGIMVLADRRFQKKRNQLPKWISQALKETDVNLSTDMAVGNARKFLRNMAQPFKAKDQEGISTWSYKDLMAHKERQDEERIQILREEAAKGANGTLDEAEYGLDANEMMDLDEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK74</accession>
    <name>A0ABR3YK74_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_006118</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000255">
        <property type="protein sequence ID" value="KAL1888573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1888573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="322" mass="37917" checksum="CB6A2B34B663D0C4" modified="2025-10-08" version="1">MLPTSPAPHAENSQPPSQELELSLVLTRQGFSGQQLIVFFNDVELPREKLRHRMYECFRRQLEAMFPREVDEKIEFLSKPRRSSEKTVVLKAESYLLIFAVECPFYEVGDLIRDLEPFCDYQQDKKIQCHTKKIRDSFDLDDYLKPSEISGKLDPCYKKRIVRLAQGVMQKTNEVYWDLPYEPNEETIRERVIKWESRALEDYLSSNFPTQKTGCIVKMIIFYWKTQRELELDHYILTFILHLHFPDSSGYMDSTAVRDEIKKHKPAFYITHAGHLGLTEAFDSMIQQNQEGQKDQEDTKSQGWKELLNPDTLEQNSYAEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKG1</accession>
    <name>A0ABR3YKG1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006072</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000249">
        <property type="protein sequence ID" value="KAL1888707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013640">
        <property type="entry name" value="Vfa1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28218">
        <property type="entry name" value="VPS4-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28218:SF1">
        <property type="entry name" value="VPS4-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08432">
        <property type="entry name" value="Vfa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="188" mass="21756" checksum="91E0AB7BE7266AC7" modified="2025-10-08" version="1">MSFDFFYVCPAHLKDRKFCSPAFDAEAEKTRIEAKHKEEIDAEVEKLKGEYAAEKAKEEEKGGKEKNKDGEKTGSKKDTETEKKEKADQKKAFSKASPQATLEEPRVFILVQQVNPRITDPLFPSLLSYLLPSPPALTTTRRTFFDIRKQKRRDLELAKRQYQQSQMNRERMAKADFWPTVPGEIPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKG7</accession>
    <name>A0ABR3YKG7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_006217</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000266">
        <property type="protein sequence ID" value="KAL1888328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07216">
        <property type="entry name" value="Pat17_PNPLA8_PNPLA9_like3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185:SF1">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3 4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="6">
        <location>
            <begin position="12"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="4">
        <location>
            <begin position="16"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="4">
        <location>
            <begin position="56"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="379" mass="41552" checksum="098D7CF9B89597D3" modified="2025-10-08" version="1">MTSNTSQPVKVLSFDGGGIRGLSSLLILEKIMENIKVAEGLSEVPKPCDRFDLIGGTSTGGIIAIMLGRLGMTVDQCIRTYRELAETAFTPKRSRIFPVSPSGAFSAKKLEGAIKRAIRENCMMQSCVEHRQMGKPTTNFCKHEDQRLHEKSCTKTVVLAITKANVETLPTLFTTYDDSTSFSGSKIWEVARATSAAITFFKSIKVGRDEVEFIDAGFGHNNPCEALIEETKKEYPGREMTILSIGTGLGDVIEIKDKRISIIKALASMATTSKAAALRLQNKYSGIGGYYRFNVENGLKDITLSDWKQASKISSHTRNYLAENREAVEKYINTIAGRGNVTQDETVLAEMPDSGKALGPASQCFHKPENPRSFAELQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKI5</accession>
    <name>A0ABR3YKI5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006232</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000268">
        <property type="protein sequence ID" value="KAL1888296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="110"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="144"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="170" mass="18505" checksum="104A9136ECAE5883" modified="2025-10-08" version="1">MGIIDRIQAKLELMRLEKRYTRRRHRRSTFQTNAVYVDGEYIHQTPNMTGSSTDSHAGSNTNPTGASDMNMGGGFMSSSSSSNHRHNADVFDAHLNTRPSHSRFESAPISPASLSSQNSSFASSDHQQQRNASKRSASMQMPAFGGSFVPSVASSSHSTKKPTTPPSSAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL12</accession>
    <name>A0ABR3YL12_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ATP-dependent RNA helicase ucp12</fullName>
            <ecNumber evidence="8">3.6.4.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ucp12</name>
        <name evidence="8" type="ORF">Cpir12675_006036</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000243">
        <property type="protein sequence ID" value="KAL1888809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23827">
        <property type="entry name" value="RWD_YLR419W-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056328">
        <property type="entry name" value="DSRM_DHX29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059023">
        <property type="entry name" value="RNA_hel_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF267">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE YLR419W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24385">
        <property type="entry name" value="DSRM_DHX29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26026">
        <property type="entry name" value="RNA_hel_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="605"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="836"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="203"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="11"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1362" mass="150838" checksum="C58D806693DF7560" modified="2025-10-08" version="1">MAKKGSKNQGSSSSSAPVLPSAANAKKSKKDPKKDATAGSSSLAATKAAAAEAAAALAPPKPTAKQIIGGASWTGKLPVNLFNEYCQKQKWEKPVYEIRKTPDGYLGWVTLSAKDIKTQEITTLDSFKMPLAHKHLILRQTALEARHCTATYALFRTCSMQNRHGVLPPDYKSLWKEFVAIKAADVKEGKAWMYEADPFKSQRERDAAKASAEKKRRETEAAKAKEQKASAVPGLVLRGKNLEVEDQKALAMRGWKNAPRIEMGKKSRTSIEALLRQGSTWNPYGIKLPKTTAASIVKELSRIGFRPSHVEEATEHCKDREECLEWLLLHVPEDDLPSWALPERYMAGIAVAETNLKKEAAIKRLSLPGYAQDLCLKAYEENNGDESMAAASLQNMLVGSPPVDAGTGIELDINQTPQGLWQDEVASIESVYADQFKRISNSAIQIKLQSVMNGQAQIDAYFQLQRAPDYPNKLLLGVIANLPSYIRLSILKQALDYIEQDIKGEEMKMYFVIDWVQEHVNAFIENPGRLLEISAVASAASETKPILSDSANYSKRHKAKPTFISWREDPHSRNQWLERVRSKQWVAMEAKRQELPAWKIQDQLVQTVEDYDVTIISGETGSGKSTQSMQFILDNLYSRGLGIHANMLVTQPRRISALGLADRVAEERCTRVGDEVGYAIRGETKRGKDTRITFMTTGVLLRRLQVAGGDIQDVISSLANVSHIVVDEVHERSLDTDFLLTILRSVLTTRRGLLKLVLMSATLDARSFSDYFERENLRVGLVNIEGRTYPVTDIYLDEILHMTGFLETYDQGDDSENSNLVGKAIQKLGPRINYDLIIEAILAIDRQLGDGNRGGILVFLPGVVEISRVCNELARFSSLFTLPLHASLDTKEQKRVFQRPPHKRRKVVVATNIAETSITIDDIVAVLDSGKVKEISYDPVNNMRRLEENWASKAACKQRRGRAGRVQQGTCYKLYTRKLEAESMADRPDPEICRVPLEQMCLSVRAMGIRSVSSFLAQAPTPPSTTAIEGALSLLQQMGAMDGDELTALGTQLSIIPADLRCAKLMVYGCIFGCLGDCIAIAAILSTRSPFVAPQAKRDEARAARMAFSRGDGDLLTDLAAFRAWQERLSQGYGQRQTRAFCDENFLSYNTLNDIDNTCSQYRDALVETGLLARNSSGDRHNKASTASPSLLRALTASAFSPQLARVQLPSKKFASIASGAVEVDPEARLIKYFTKEQGRVFVHPSSALFDSQGFSGRAAFVSYFTMISTSKVFIRDLTPFNAYTLLLFAGTLALDTLGRGLIVNDWLYLQGWARIGVLVARLRSLIDSVVARKIENPQEDVSASKIIQTVVHLIELDGLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL99</accession>
    <name>A0ABR3YL99_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pro-apoptotic serine protease NMA111</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Pro-apoptotic serine protease nma111</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_006130</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Nuclear serine protease which mediates apoptosis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S1C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000256">
        <property type="protein sequence ID" value="KAL1888566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06786">
        <property type="entry name" value="cpPDZ1_ScNma111-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06719">
        <property type="entry name" value="PDZ2-4_Nma111p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025926">
        <property type="entry name" value="PDZ-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46366">
        <property type="entry name" value="PRO-APOPTOTIC SERINE PROTEASE NMA111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46366:SF8">
        <property type="entry name" value="PRO-APOPTOTIC SERINE PROTEASE NMA111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12812">
        <property type="entry name" value="PDZ_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13365">
        <property type="entry name" value="Trypsin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PDZ-like" evidence="8">
        <location>
            <begin position="436"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ-like" evidence="8">
        <location>
            <begin position="913"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1037"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="33"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1037"/>
            <end position="1048"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1888566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1065" mass="117625" checksum="1D76E10F182360D2" modified="2025-10-08" version="1">MSSRPKRKAASSPGDARAQKQHRPVNGQPSIMPATAATGPASAAPSTANGLNNNSSSGAAAPPPAGNSIRMPVHSYPTANLDGDISDDRDDTRSDGLSDDIVEEFIDMPSQETLEWQAAIGNVVPTVVSIRFCLPCSFDSEFADTSEATGFVVDAERGYILTNRHVVGAGPFWGYCVFDNHEEVDAYAVYRDPIHDFGILRFDPKAIKYMPVRALELRPELAKVGLEIRVVGNDAGEKLCILSGVISRLDRNAPEYADGYSDFNTCYYQTNAAASGGSSGSPVVNIDGHAIALQAGGRVDGASTDYLLPLDRAARALECIQEGRPVERGDIQCQFLLKAFDECRRLGLSPEREAQVRREFPHVNCMLVAEIVLPEGPSHKKIEEGDVLIEVEGEIVPDFIRLDEILDSHVGKTIKVVLQRVGQEIEVEIEVGDLHKISPDRFLTVSGATFHDLSYHQARLYSVPCRGVYVCEAANSFRLKTAESGLVLESIDHRLTSNLDTFAAVMQTIPDRARVVVTYRNLRDLHTLHTTIVSIDRHWTKKMEMSVRNDKTGLWDFTEIGKALPPVAPVPRKASFIELQHTSYPAVAELVRSFVQVSAIMPMKIDAFPKNRRWAMGVVIDAEQGLVVVSRAIVPFDLCDITITIADSIQLEGKVVFLHPLQNYVVVRYDPKLVDAPVQSARLSTQGLGQGEATHFIGINRQGRLVHTATSVTEVTAVAIPPNSVAPRYRAVNVDAITIDSNLGGQCGSGVLVGSDGTVQALWLTYLGEQSSCSRHDEEYHLGLATPTLMPIIAELQAGRQPNLRMLSAEFSAIQMSQARIMGVSEEWMHKVSEANKTHHQLFMVSKRWLVQDEEDDDLGLHEGDILLTLNDKLITRVAELDIMYSNDMLMARVVRRNKELELKLTTAKTDDVETHRALWFCGAIIHRPHQAVRQQISRLPSEVYVSARSRGSPSYQYGLAPTNFITHVNRTETKTLDAFLDAVREIPNNTYFVLKAVTFDGVPWVVTMKKNDHYFPTVEWKKDDSDPCGWKRTVYEDGNSKDDKTHAALEAPIEEVDTDNAMSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLD9</accession>
    <name>A0ABR3YLD9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Deubiquitination-protection protein dph1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_005920</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000230">
        <property type="protein sequence ID" value="KAL1889111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14324">
        <property type="entry name" value="UBA_Dsk2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006636">
        <property type="entry name" value="STI1_HS-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015496">
        <property type="entry name" value="Ubiquilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10677:SF3">
        <property type="entry name" value="FI07626P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10677">
        <property type="entry name" value="UBIQUILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23195">
        <property type="entry name" value="UBQLN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00727">
        <property type="entry name" value="STI1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="3">
        <location>
            <begin position="13"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="2">
        <location>
            <begin position="375"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="417" mass="43757" checksum="2327954620457FC8" modified="2025-10-08" version="1">MADSTPAATNDSITFKVKASGDRLHTITISQSVTVKELKVKLSDETYENIPIERQRLIYAGRVMKNDDTLVTYNIKPNNTIHLVKSAASNATPSSASSTLPAAAAVPTNIATGVNNDPLAGLTGARYAGHVQLPSRDLFGADGGMGAPPNEDELARMLDDPSVQQTLNAALDNPQFIDQMIRMNPQLASIPNVREMFQSPFMRHMLTNPDMMRMSARMSRSMGGVGGSGFGSFPAPGVTDSTPGTTTTDSSNPSTSTDGSGAGATPGSTPNPAMPWMMNSPFGIPPPGAFGGANPAENPFLALFNPPGTSSGATSDVNTSNNRSAAPGDLPPNPLSLPGISRFPDPNALQEVMSLFQGMNGGAGTGAPTPVDNRPPEERYADQLRQLNDMGFFDFDRNIAALRRSGGSVQGAIEHLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLE7</accession>
    <name>A0ABR3YLE7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Grh/CP2 DB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_005890</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000227">
        <property type="protein sequence ID" value="KAL1889180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007604">
        <property type="entry name" value="CP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057520">
        <property type="entry name" value="GRHL1/CP2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040167">
        <property type="entry name" value="TF_CP2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11037:SF20">
        <property type="entry name" value="PROTEIN GRAINYHEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11037">
        <property type="entry name" value="TRANSCRIPTION FACTOR CP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04516">
        <property type="entry name" value="CP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25416">
        <property type="entry name" value="GRHL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51968">
        <property type="entry name" value="GRH_CP2_DB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Grh/CP2 DB" evidence="7">
        <location>
            <begin position="166"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="497"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="108"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="518"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="707" mass="78915" checksum="C6CF985D5FD7B46B" modified="2025-10-08" version="1">MMGFSNAPLPGGIPDRHYASGHPSSHHSHSSHYYGHFISHPPPHSTTPVSENTPRRLSDLAPSSAGLYPHSHPSTPSSHHPAPNYASQPLSPRQYSRYDHTPMPAPYEQQSLSAAMSSSIAPGPTPARVNVQSPRSMQGPGLLSAPALSMPPGPHIKSEPPSHPQSPFRFQTTLETPTSMIQRDDEIPITYLNKSQKYRIIVCDSQSRTIQPPGSKVQYRTSIRVTFDDAGQRREPAAAWELWKETRDTRTDDESRYSTGQLRALEFIDEGDRRRPFGTEVQLERHSFDSFSVIWSPTSLENAQCAINARFNFLSTDFSQTKGVKGVAVRVVAKTSLYSNPNANTPNSNTFSELSYCKAKVFRDHGAERKLAIDSDRVRRSIEKIRHTLRGSERGMAPKRKDRITKRPRNAARGRLLPRNIMDRSIDDEKFEIDDDMDRNDDDIGYVSPTESLQIQLRSLEQMSRSTSSCTVFVLPGEEGDDPDLFPVKLYEDRHERPHGSVSDISRQHHHSWPASECTGSISDSQSRVPLGHPPSMAISPTNAADVDHTYRPPVAAASHAIACFYLRRQTHTTHSAQQLPRVRLTPEDTLFRATYLMKRTASELCQRIGAKWKVDTSTSRLVHVNANSIEVCVDDDFVQQMPEGQAYDMELLKVSSPRLPPALPSVSVLASGTGSLSLPSILNDTHSSPRQQRENIYEIRLVPVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMF9</accession>
    <name>A0ABR3YMF9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005733</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000212">
        <property type="protein sequence ID" value="KAL1889540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="181"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="191"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="289"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="298" mass="34801" checksum="5D5D5E8467E55EAA" modified="2025-10-08" version="1">MAQSKTPTYVRIERGRDSLRMNHEYNRDIKETFPIGSPASKNIGFELPDNFKKRDDEIYKLKLAHRESKSQTEVLKQQLDSCLKENEYLQRELQKAKVNGGSVEKTYRRAQCCTSSSRKETEHILSLRQNVSKLETEIYRLKQDTQFYKEEIHARRPRCDTQSKRERCIIVHSPFLHDHAISQSRSRSRSRSCSQSCSRPYSRSFSRSRSRSRSRSRSRSRSRSRSQSSSCNIRASIRGGANSPSYESASDEYHNIWSTGTRNRRLASEPHRPTQHVHFSPPPPQAPYRFREGWGAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YML2</accession>
    <name>A0ABR3YML2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Developmental regulatory protein wetA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005844</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000222">
        <property type="protein sequence ID" value="KAL1889295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="424"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="501"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="598"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="691"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="833"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="925"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="990"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1283"/>
            <end position="1388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1438"/>
            <end position="1585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="269"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="525"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="561"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="609"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="699"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="731"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="763"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="834"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="990"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1332"/>
            <end position="1347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1373"/>
            <end position="1384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1450"/>
            <end position="1464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1465"/>
            <end position="1474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1475"/>
            <end position="1494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1524"/>
            <end position="1540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1571"/>
            <end position="1585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1585" mass="163962" checksum="16DEDA37F718F485" modified="2025-10-08" version="1">MASAVMPDTDWASSGNMQFEEYLDFSQATDFGDQMFISGLADDHLEQQQQGQEQEHMFGTVPMSSISPPETFVPCSMAGNSVDVSMGLGLGFGEWANAANAGASGGASTANFEMHHNHQSHSLESSNMEAPTSNHPNLGLGLGLGLGVGVEEAGSEMDVEIEMASPSVGMPSPNQQRRREQGQDHLLDLAQNEQHQHKGQQQQKELEIHQQHQHQQQPGMRGLSLSAAVSASDLLELERITLKSPHRPRIAMVSSSGDLSQQAKQSEDQSQYQYQYDQHQQLHQIHQLQQQQNTRLQQVSPSMSGQDLLAVPISGLPVRGGPSSNVTVGAPVVGAPPATTSTSPAGGSSALPVNVIMTRPVGGPSVTASADLAQANHSSSSYEKHAPLGSPSGTTAPSMSSFSSRRLDFSRRFVSALVSPIRKAAGKRNKGKHGKSSTNSGGNDCSGRLGNHPRTTASNVASGSSLAGGAEAAAIKSSTGGVATAAPAAAPAATAISASMVATTESQDHGQAPHSHHNPFGFSYSHAPPHSTLHTHTPPHPHQAALADGRSNSTGLHPAATPSQPSSCTTNSSTSDRSNSRQSASVGINHAQIEHTNNDSATTAGPADPVAASVVSSLPPSSSAVSMAMPLSMSMLTFPASSLSFCSGVSAASVSSSPLAHAQSYHSLSSHAQAQAQAQAQAQMVHAGSFGNLRGSSFQQQERQQHLTQQSCEDLQHYKQHPLHPQRQPMAASSSSRPTVLYQNSNTSGKHRHTPSSITLQQASPSTTAAAAATNSTATTATPGPSSSSCKAAATVATPVTGNTPISVTPLIDKEAAAGSSSLSLALNRHAPVATSTGDSGCSPLAQSAPTAPNRGPSSPPSVCSPPSLAMSSANAIASATIASTTATSTIAAAVAAGPDSFPSASAPLSTTASATVVASSISTSTPSSSFLAPLENSSSFSPSSSSDPAPASTSSSVSLSAARPRPKLSSSVSVSSGLSSLQQSSSISAALSPSSSTSPHTSSSLQSHPHRLVHHSSVHFPTTAADSITLQTPPLNLFIDPFLPLSFNKSAPPSAQASSFNTGLSVPAPNMVDYQPLQSRSNSMFDADSIDPLALTSPTPRRAMTMSISGPSLGAGLGSGVTDMASSVRDPTVVWPMTSAGAENTMLWSVYGNDATAVHDNNMWALNMMHQQSQDGQGSADGTEHSSFTDVTAHYTFQQPSHHPQTVSPHDLSHNELTEYPGLTDGSMIHNSHMMLDPSASHTANPYENNGIGNINGPLAHHFINPAQTQHVMAQAPQLVAAPASAPNDQQQRRRQPRAPSSSMRHMHSLPVISSRKQRPNRSESPSSGSGAPGSGSGAHGHGHGSVPGHSRTLSGSASIPPHAIRKKRSVSRTLARSASNGSIDFGGSSAGLAMSVSMNQLASANVPSAGTDTMNHNVQNMQNVQAVQNVQNVQNTINNHDGYNGLLSQQSSQSSHSGYSVQHAHNSSNPHDQSNNGSQSSSSNSSSNTTGGISFMNYTPKDGHILMTGVAPSGSSKTKAKREREAVERQRRLSEAARRAVMAAGGDPGQIEGWIKVSDDESPPAAAEVHIKSQDPDSESESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN40</accession>
    <name>A0ABR3YN40_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000204">
        <property type="protein sequence ID" value="KAL1889780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="208" mass="22403" checksum="3706355147029B33" modified="2025-10-08" version="1">MGIIYNNTGSPGSNALTASGANQNANSPEFNRDDHLPEVVIETHDNQQSQNPQYLQHPHPISPNSTGGLSSLLSGPAWASETNTSISGGAQFTNSSTVSYDSEVKTDSGKASYGLESHATSSAALPAPMSPQTTISDDHPVPYPPNAQHASAPYPGSYTQEYAENQPQTSTYRPDSTAQLPPRLRQRQFQIPQLHQVLTKCPLRMDCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNE8</accession>
    <name>A0ABR3YNE8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Spermatogenesis-associated protein 20-like TRX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005628</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000203">
        <property type="protein sequence ID" value="KAL1889831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02955">
        <property type="entry name" value="SSP411"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024705">
        <property type="entry name" value="Ssp411"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004879">
        <property type="entry name" value="Ssp411-like_TRX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42899">
        <property type="entry name" value="SPERMATOGENESIS-ASSOCIATED PROTEIN 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42899:SF1">
        <property type="entry name" value="SPERMATOGENESIS-ASSOCIATED PROTEIN 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03190">
        <property type="entry name" value="Thioredox_DsbH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006402">
        <property type="entry name" value="UCP006402_thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Spermatogenesis-associated protein 20-like TRX" evidence="2">
        <location>
            <begin position="13"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="745" mass="81446" checksum="402E89CEB6EF5A64" modified="2025-10-08" version="1">MHGGHYEEPLVNCAAKGQSNYVRQQKDSPVAWQLLNEDAIARAKAEDKLIFMHIGYSACHYSRLMTNETFAFLGIARELNENFVPVIIDRDERPDLDVVYMNYVEAVHGVGGWPLNVFLTPELEPVFGGTYWPAPNNDRAADNEDRAADFHQILLMLQKLWSEQRSRLRQEAREIIGQLLAYASEGTSSEPVSTAAMAVAGIGAKDLQAKPSRAQPSTANNKTPMVATSGVGNDLDIDLMETAYTQIAGTYDAVHGGFTGTVKYVTAPKLSLLLRLPHFRSEVRDMVGYDETEMALRMAKDTLRAINRSGLHDHLGRGFSRCSVTADWSLPFFERLMVENALLLGLFTDAWLDEGGARESEFFPVVLETADYLSSAPLLAPHGLLLSSEAADSRFSQHDSHDGPGAFFLWTRRELDTVLGPGVDSDVAAAHWNVQPRGNISPNNDPNDDFVNRNVLHVVKDVPALATQFNQPEAYIKTVLAGARTKLAEFRAKERVAPSVISNAVAGYNGVAIAALAKAGAAVQYVESALGKKYIQAATSLAQKLKALLWDTKTTTLFRMLCEGKRSDTPAYAEDYAYIIDGLLALYAATLDESHISWAVELQDAQIEAFVDATSASRGGFFTARENTPHLLLRLKAGMDGTLPSANAVSATNLFSLGTMLAVSGRTDTDKKKAAEYTALARATVEAFEAELLNFPWLFPGLLGCIVPYRLGVKTVVVKDGEKAEKELKEARLAPREGPVVFVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNR9</accession>
    <name>A0ABR3YNR9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TOM1</name>
        <name evidence="10" type="ORF">Cpir12675_005569</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UPL family. TOM1/PTR1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000198">
        <property type="protein sequence ID" value="KAL1890003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010309">
        <property type="entry name" value="E3_Ub_ligase_DUF908"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010314">
        <property type="entry name" value="E3_Ub_ligase_DUF913"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050409">
        <property type="entry name" value="E3_ubiq-protein_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025527">
        <property type="entry name" value="HUWE1/Rev1_UBM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254:SF67">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HUWE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254">
        <property type="entry name" value="HECT DOMAIN UBIQUITIN-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06012">
        <property type="entry name" value="DUF908"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06025">
        <property type="entry name" value="DUF913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14377">
        <property type="entry name" value="UBM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="9">
        <location>
            <begin position="3832"/>
            <end position="4168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="224"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="286"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="743"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1547"/>
            <end position="1596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1939"/>
            <end position="1997"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="2023"/>
            <end position="2078"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="2321"/>
            <end position="2537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="2618"/>
            <end position="2645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="2852"/>
            <end position="2926"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="3026"/>
            <end position="3056"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="3122"/>
            <end position="3150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="3266"/>
            <end position="3286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="3354"/>
            <end position="3374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="3422"/>
            <end position="3451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="3687"/>
            <end position="3736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="312"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="751"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1584"/>
            <end position="1594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1939"/>
            <end position="1948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1983"/>
            <end position="1996"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="2023"/>
            <end position="2033"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="2043"/>
            <end position="2060"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="2067"/>
            <end position="2077"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="2360"/>
            <end position="2414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="2433"/>
            <end position="2463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="2471"/>
            <end position="2486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="2489"/>
            <end position="2505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="2513"/>
            <end position="2529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="2852"/>
            <end position="2903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="3026"/>
            <end position="3041"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="3122"/>
            <end position="3137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="3422"/>
            <end position="3441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="3687"/>
            <end position="3708"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="7">
        <location>
            <position position="4135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="4168" mass="466198" checksum="10B37F52C9469EAA" modified="2025-10-08" version="1">[encoded data, 4168 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ06</accession>
    <name>A0ABR3YQ06_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 15">Dolichyl-phosphate-mannose--protein mannosyltransferase</fullName>
            <ecNumber evidence="4 15">2.4.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">PMT1</name>
        <name evidence="18" type="ORF">Cpir12675_005409</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17377"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:13546"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137321"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 15">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53396"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13547"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137323"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 15">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Endoplasmic reticulum membrane</location>
            <topology evidence="1 15">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the glycosyltransferase 39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.109" evidence="4 15"/>
    <dbReference type="EMBL" id="JAWDJO010000184">
        <property type="protein sequence ID" value="KAL1890395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004169">
        <property type="term" value="F:dolichyl-phosphate-mannose-protein mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23283">
        <property type="entry name" value="beta-trefoil_MIR_PMT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003342">
        <property type="entry name" value="ArnT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036300">
        <property type="entry name" value="MIR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016093">
        <property type="entry name" value="MIR_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027005">
        <property type="entry name" value="PMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032421">
        <property type="entry name" value="PMT_4TMC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050">
        <property type="entry name" value="DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050:SF50">
        <property type="entry name" value="DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02815">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02366">
        <property type="entry name" value="PMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16192">
        <property type="entry name" value="PMT_4TMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00472">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82109">
        <property type="entry name" value="MIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50919">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 15 18" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 15 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="205"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="290"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="619"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="684"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="725"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="17">
        <location>
            <begin position="343"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="17">
        <location>
            <begin position="420"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="17">
        <location>
            <begin position="489"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="873"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="883"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="926"/>
            <end position="938"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU367007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1890395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="952" mass="106325" checksum="385A1E27B2C3AC81" modified="2025-10-08" version="1">MARSSSKSPALAGMGTATQSSEKRSVLASSKNSRKSAVTTKSSYASDGVKDNDVFLLPLMDYQWMILVTILAAGVRLFRIYQPDSVVFDEVHFGGFATKYIKGRFFMDVHPPLAKMLIALAGWLAGFKGDFDFKEIGMDYVEPRVPYVAMRLFPALCGIMLAPTMFLTLKATGCRTTTAVMGSLAIVFENGLLTQARLILLDSPLMIATAFTALAFTSFTNQHELGPAKAFDLSWWFWLIMTGLGLGVTASIKWVGLFTIAWVGTLTLVQLWVLLGDTVNVSPRTWLKHFFARIVCLIGIPVAFYMAMFAIHFVCLVNPGEGDGFMSSEFQATLNSKSMQAVPADVLMGSRVTIRHVNTQGGYLHSHPLMYPTGSKQQQITLYPHKDHNNVWLIENNTQPLDINGEPINGTQAWDNLPEPAYLKHGSLIRLYHQPTYRRLHSHDVRPPVTEADWQNEVSCYGYEGFEGDANDLFRVEIVSSKSKGELAKQRVRTIETKFRLVHIMSGCALFSHKVKLPEWASEQQEVTCARGGTEPNSVWYIEHNEHPQLGDDAEKVNYENPGFLGKFWELHKVMWKTNAGLTDSHAWESRPPSWPILSRGINFWGRDHRQIYLIGNPVVWYSATLSIVLYIAFKGLAVLRWQRSYNDYSNVVFKRFDYEVGSAVLGWAFHYFPFYLMQRQLFLHHYFPALYFGVFAFAQVADFVTARITIPSLKSGKSYLMNKVAAVVFLVFTVVAFSLWAPLAYGNMWTKGQCQSLKLWNTWDYDCNTFYDTYDQYTNAPVSSQSAIHTDAGNAGKPAAAAPIEPNEAADQVPMGGKALVSDAPQGLSQKLVQREETVEYRDQDGNLLDPEVVEGLKGKVEFQTRYETRTRLIDSEGNELPAQGGFAAEPAQQAPPHPDVEGIDPETKHVSDNPAPVVPVVHQESVDGAKEAEKSKPKPASEGNDATKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ95</accession>
    <name>A0ABR3YQ95_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005354</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000181">
        <property type="protein sequence ID" value="KAL1890491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="139" mass="15003" checksum="8AF538AF5132787A" modified="2025-10-08" version="1" fragment="single">MPDTPLAPPPIYTPAPNSFVDAAGAPPTTDASVPQDESDMISRKRALVDGKKNDLVFDVSLSTDEDAILKLLEKVSDHVAGKHHLLTEFQEKHHLTKLATVAKASTTSSSVNVPTTDVGNKPSHEDRLKAFKMSLSVYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQJ0</accession>
    <name>A0ABR3YQJ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">P-type Na(+) transporter</fullName>
            <ecNumber evidence="18">7.2.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="primary">cta3</name>
        <name evidence="24" type="ORF">Cpir12675_005530</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24 25">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>K(+)(in) + ATP + H2O = K(+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:75815"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>Na(+)(in) + ATP + H2O = Na(+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.3"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="20">
            <dbReference type="Rhea" id="RHEA:14634"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IID subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.3" evidence="18"/>
    <dbReference type="EMBL" id="JAWDJO010000193">
        <property type="protein sequence ID" value="KAL1890115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006414">
        <property type="entry name" value="P-type_ATPase_IID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01523">
        <property type="entry name" value="ATPase-IID_K-Na"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08282">
        <property type="entry name" value="Hydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15 22" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0915">Sodium</keyword>
    <keyword evidence="16" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="6 22" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 22" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="323"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="830"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="867"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="908"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="955"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="1005"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="1037"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="23">
        <location>
            <begin position="10"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1105"/>
            <end position="1129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00035017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00035029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00048599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00049499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAL1890115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1129" mass="124164" checksum="7404DC1F396495FD" modified="2025-10-08" version="1">MSKTTADFKHPFLLSVEDTARDYSTNIDAGLTSSQVSQLQSIHPPNELDIGDGVAWYKILSKQLLNAMILVLFFVMVLSYAFKDWIEGGVVTVVIILNVAIGFWQEYKAEKKMDALRALSSPSATVLRDGVSSVVPNAQVVPGDIIYLKMGDTVPADVRLFEAMNLACDEQSLTGEALPVDKITENTIIVHGTDRIATEDSEVGIGDRINIAYATTTVKKGRGAGIVIATGMTTEVGKIASSSTKKNRKPGRSMNFKKYGKRQAAHGVALTAYDKVGKFLGLTEGTPLQRKLAGLAYVLFGCALLLAVVVFGVNEFHVPNEVVIYATSLGIAIIPESLVAVLTITMVVAVSVMNKANVVVRDLSALEALGGVTNICSDKTGTLTQGSMIVRKAWLPKNHLYTVHESQNPSDPTQGHVTHQEYTAPKPELKQERNFDEERSALALKFDVPEEKLNAANQASGNDAAGNKEPKEEPAKVTPALRAFLLSSGLCNLANVRYDNDSQKWTAAGEPTEVALQVFALRFQYGRKALQGKGWKQVAEFPFDSSIKRMSVIYNAPIDDDSIEGCAENSIVFTKGAVERVLDLCSHFGYNEDRTELTNEIKDEIMEQMSALASQGQRVLCIAYRKWDGRYVAEEQGSDDSTGENSLRNRVEQGLTFLGLVGIYDPPRRETKMSIAECSTAGIRVHMLTGDHPDTAKAIAKEVGIIPKNLSVLPDSIKQTVVVKATEFDKMTDEQIDNMEELPLVIARCAPNTKTRMIEALRRRGAFMAMTGDGVNDAPSLSAADVGIAMGSGSDVAKSASKIVLTDDKFNSIVSAIREGRRMFDNIQKFVLHLLTSNVGEVILLVAGLGFRDSRGYSVFPVSPLEILWINMVTSSFPAFGLGREGAASNVMRKPPHDKNRGVFTNQILVDMIVYGVLMGFATIMTFVIIVYGNHDGNLGNDCNKKWSESCRPVFRARAAVFAELTWLILLSAWEFKDLRRSAFRLNDDETNRLSVFKDMYANKFLFYSVVIGMLSVFPVVYIPGLNTNVFKHRGISWEWGLVVGFTIFFIAGIEAWKLIKRRFHLLEDRPVKRGAYAQGSSDETAGTFGRSMTMVSFKSWRTFRRSETKESRASSSRRKRMSVGVTPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQQ6</accession>
    <name>A0ABR3YQQ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pectate lyase</fullName>
            <ecNumber evidence="10">4.2.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_005274</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Eliminative cleavage of (1-&gt;4)-alpha-D-galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.</text>
            <dbReference type="EC" id="4.2.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 10">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the polysaccharide lyase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.2" evidence="10"/>
    <dbReference type="EMBL" id="JAWDJO010000175">
        <property type="protein sequence ID" value="KAL1890694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004898">
        <property type="entry name" value="Pectate_lyase_PlyH/PlyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33407">
        <property type="entry name" value="PECTATE LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33407:SF9">
        <property type="entry name" value="PECTATE LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03211">
        <property type="entry name" value="Pectate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="8 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045011375" description="Pectate lyase" evidence="10">
        <location>
            <begin position="19"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1890694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="233" mass="24739" checksum="2F25F099B9CC5E1D" modified="2025-10-08" version="1">MQFSNFFLALAAIPMAMGYSYCPTKSLPAAKGYKALKATQYITKGSVYDAKYYKIDRGVSCTAQTEGGEKDAVFVLEAGATLRNVIIGAKQREGVYCVGPCTLENVWFEDVCEDAISIKGNGLATISGGGAFKAADKVIQHNGCGHVNVVNFYAEDYGKVYRSCGNCVGNCARTVHMSGVTALNGGELIGINPNLGDKATYENNCFDAKTQCQGYKGCDKSKGACDIPKTSAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRM9</accession>
    <name>A0ABR3YRM9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">NADH-ubiquinone oxidoreductase B12 subunit family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_005136</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I NDUFB3 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000164">
        <property type="protein sequence ID" value="KAL1891010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012576">
        <property type="entry name" value="NDUFB3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15082:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15082">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE B12 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08122">
        <property type="entry name" value="NDUF_B12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1891010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="96" mass="11059" checksum="781F1B914CE21C49" modified="2025-10-08" version="1">MFLTRVLRAAANGPKPNITGFDMKAFRAAGGQPRYDPWERAEAWRYTGEFSRWNRYKNSLPGLGTASVAFAAYCAYEHFFLQDEHHGDEHHAEKEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSG8</accession>
    <name>A0ABR3YSG8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PI-PLC X domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005223</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000170">
        <property type="protein sequence ID" value="KAL1890827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051057">
        <property type="entry name" value="PI-PLC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593:SF146">
        <property type="entry name" value="PLC-LIKE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26146">
        <property type="entry name" value="PI-PLC_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045916501" description="PI-PLC X domain-containing protein 1" evidence="1">
        <location>
            <begin position="17"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="278" mass="31193" checksum="8EFC4A71DCC75FC2" modified="2025-10-08" version="1">MNLLSIILAFAFPIIADDLACNGDVRLCNRRYSNISLIGSHNSAFVGILPTNNQYVSVTEQLNIGVRFLQVQTRGHDGSIQLCHTSCWVLNAGPLSGYLREVATWMAKNPREVLTVLITNSDGMAVERFAEAVRDAHLDGIVYRPAGQPALNEWPTLQEFLDYGVRLIVFMVLDSYADTTKVDYILPQFLYQWQNAYGQTDSAFSNCSIDRPKRIQHPETYMYMINHFLDVQLPFDIIIPNQFEAGSTNSLESIIKQAEMCGVQWGVKPNVILVGSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YST4</accession>
    <name>A0ABR3YST4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rab-GAP TBC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005198</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000168">
        <property type="protein sequence ID" value="KAL1890910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF20">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="906"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="553"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="627"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="722"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="429"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="637"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="662"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="727"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="751"/>
            <end position="796"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAL1890910.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1187" mass="127417" checksum="CA761CD15527BC05" modified="2025-10-08" version="1">MANKSNSSSVAAGPRRAHHVSMSSSMPIASPVSGSPSTSALSSSASASINAIGLKRSTSAHSAASSRSHRSVRTRRRPGHHSQQSPSTSSINTTAVNTISDKSLTSFPSFSGESPLLDANLGFGSISGKLNNATSAAINATSTPVQVKPLGIRPSLMPRTQSAAGSLQNWKHHHSTPRDRFGIVPSPALAEPVTTPATTSSAMIVENLTRGYEDATESRGLFEDDPIAITKIPGALHLAGDDHIERLIARHGAVSLVRQIAEDLAMRDVQMSAARRRAEERERALRRICRESGLSNLELEQRLKAVETEMRDVDSTKRRPASMLSDMMSDAMDCDVLKDTNDATIRAVSNSAIGVATGGKQNPSITVTKGTIRGWKDYIWGGTAKKTDSPSHTPGKTGVVRGTGSGNDKRLPLQESLFHPPEHDAPGFSHVGGSVRSSSRSSAVSIKTTESESSRKTSLASLALRLVAGGGSSSVRDSDTQRGRSKIAASNLPAHAGTVSARPSPAARALSMQLAPKGSMGSLNSAKSAAISSTVRRSGATPISVPARGALPERWDTMKNSPPGAVSSTDPVQSDENFGPVEMDTILPPDAQPPTLTHIYNRYAIREKLLTDRYGFIYDQRRKKRQRDAAKLAQSGGKDKRNIHKEMLTSNKARAGISPNEVIEEGGDEEEDQDGCPPSPSQESAADAPKSRWQDYLKVATFPTELLAHMPSINMPFLEVTEGSDLPSKSPTPSNSASTTSVAQGKIRGFAPTASTTTSAPVSTQGKTPSSSDSTTATTATATASSSSTTSLPSTSQHEAIATSDDTEPVKLLLKQLSDMHDHLQRERTVRWNDFLRKVRAERKREGEAAAAAAAAAAEARFEAPAVILPEAKLTDGEMIGISGLGNKGKVGRAKWNEFKTLVLSGIPVAYRAKIWAECSGATGLRIPGYYDDIVAQGKNGLDETVVSQIDMDIRRTLTDNIFFRKGPGVKKLNEVLLAYAHRNPDVGYCQGMNLIAANLLLITPAAEDAFWILASIVELILPSGYYDHWLLASRADQHVLREYVASVLPRLSSHLDALGIELEALTFQWFLSVFTDCLSAEALFRVWDVVLCTHDGSTFLFQVALALLKLNEPALLNCEGSAAVYTYINHQMTNHAISIDGLVQASEGLRRLVKRDDVMEKRERAQEREREVLRQRELRLAAAASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTV3</accession>
    <name>A0ABR3YTV3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Aminodeoxychorismate lyase</fullName>
            <ecNumber evidence="1">4.1.3.38</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ABZ2</name>
        <name evidence="1" type="ORF">Cpir12675_004967</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.38" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000154">
        <property type="protein sequence ID" value="KAL1891455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008696">
        <property type="term" value="F:4-amino-4-deoxychorismate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1891455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="285" mass="31254" checksum="5E09F1DE29EDE374" modified="2025-10-08" version="1">MAEEFNIISSLRYDPLLEAAYQNPDFPHAAWNSAHRSRHYMLDFHRDRLNRAATHWVWNTARDTISGPGGLANLASIIDAAVQDAGAQDRAHAVRLELSRDGALKAVLRDVDPATLEDLYPSEFAVPALAPLTSAALTEITLPSFTVHLDTCATEASPFTHYKTTKRDMYNAARGRLGITAGNSAEVLIVNSRGGVMEGSITTPFFWRGGRWVTPPIPTAYQDHLGAGGQDGTTRRWALEQGFAVEDTVHVDSIQDGEVIWISNGVRGFFKATVRRKPSVARATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU89</accession>
    <name>A0ABR3YU89_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_004938</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000153">
        <property type="protein sequence ID" value="KAL1891461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.100">
        <property type="entry name" value="DNA polymerase, Y-family, little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036775">
        <property type="entry name" value="DNA_pol_Y-fam_lit_finger_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1891461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="136" mass="14735" checksum="0338A58C01C253FD" modified="2025-10-08" version="1">MLASRLVEEALKSLLRKFGVGETEWQLILLNICVTNMVAAAGEARGVAGSSWDIVHMFQQQDEVLRPFKLIEIGGDDNGASCGENSGCELAVSEEELNVWESATGNDSDEDSLKNPLPTMWETGFVVCHDSAFAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV96</accession>
    <name>A0ABR3YV96_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Up in starvation</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">USV1</name>
        <name evidence="7" type="ORF">Cpir12675_004584</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000133">
        <property type="protein sequence ID" value="KAL1892298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF127">
        <property type="entry name" value="TRANSCRIPTION FACTOR, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G09820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="120"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="151"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="57"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="257"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="357"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="461"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="57"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="109"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="258"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="288"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="360"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="375"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="461"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1892298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="613" mass="67233" checksum="A3C484403844E485" modified="2025-10-08" version="1">MSHNNSIPAMYADSQQQSFGHRQQQQHSHPSISQNIPMRPVTPMTSEAATTLSLINSSGQSRTPATVSQSPAHATRPTALHAAHSKPQENEAKSAEGTSDSDHEDENNKRKRNKKRPHKFYCTDYPPCTLSFTRSEHLSRHIRRHTGERPFTCHCNRAFTRLDNLRQHAQTVHANEPIPADSLAAQGGRGHRHSMARKRASISQHPVATLPAAIGSAHSRSMSTPIHYRHPQYMNSFNTTPSSGPVGSVLAAPAELYQQHPPNGPQGQMMGGPWGHQPHSQPPPPPQNQHQHQSQDPSQLHHQQPQQIQPPHHGYRAQMAQHQDRVLAPVIQSNGHHAHGHNRARSLMTPAEILRPAPSHLRDNFDRVRRPSQAPSLGPSSMMSQQPPSQAFPPPGARNRGHVRGQSHGAFSLAPGPGPAPGPMVNGANPPRGYTSEREWRLANQPKFNLQEELARIRLGNSANGSNSITASAGNNGKNSQSPVTPTEDYYHQAHSPVASPTFPSCRDFTRDRASLSSFDPGRGLLPRDRANQNPVVPGPLPPHSGHHSQYPGSLAPFSRGGGGGHSRSQSWNTAVPDRVDTPPITLPRLNYDEKEVRKNRMGANPLEPDIRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVJ6</accession>
    <name>A0ABR3YVJ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_004579</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000133">
        <property type="protein sequence ID" value="KAL1892293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1892293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="59" mass="6279" checksum="B3DBE8E5275372C2" modified="2025-10-08" version="1" fragment="single">CEDFVGAHPESYTKAYWAINSVKVYKATAEEVPKALPTGLLPVAVSSTHTPMATNTLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWE4</accession>
    <name>A0ABR3YWE4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aminopeptidase</fullName>
            <ecNumber evidence="7">3.4.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_004433</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.-" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000125">
        <property type="protein sequence ID" value="KAL1892701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09601">
        <property type="entry name" value="M1_APN-Q_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034016">
        <property type="entry name" value="M1_APN-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF171">
        <property type="entry name" value="AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="10">
        <location>
            <begin position="51"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="8">
        <location>
            <begin position="285"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1-like C-terminal" evidence="9">
        <location>
            <begin position="577"/>
            <end position="901"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1892701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="926" mass="103453" checksum="21325BB0FD40BE16" modified="2025-10-08" version="1">MYWKRLPRLAPQAAARPCSTISTSNLALDLFASPEASRAMADRDILPEAFKPSHYNLSLYDLEFKNWTYNGTVSIDVAITEPTKELVLNALEIKLSSAKVIVDGKTLSSSDYTYNERAQRVSVAFGEEIPVSTKAQVVLEFQGIMNSEMAGFYRSKYNPATTAAPSVPRDDDWHYMLSTQFESCDARRAFPCFDEPNLKATYDFDIEIPDDQVALSNMPVKNEVKTKNGLKKVSFETSPIMSSYLLAWAVGDFEYIEAFTDRKYNGKQIPVRVYTTRGLKEQGDWALQHAPKIIDYFSEIFGIDYPLPKADLIAVHEFTHGAMENWGLVTYRTTQVLYDPKTSDARFLNSVAYVVAHELAHQWFGNLVTMDWWDELWLNEGFATWVGWHAIDHLHPEWQVWAQFVNEGMESAFRLDGIRSSHPIHVPVRDALDVNQIFDHISYLKGCSAIRMLANHLGVETFLKGVSNYLKKYAYGNAKTQALWDALSEASGQDVTALMTPWIGNIGHPVLIVEENKTGDLKIKQTRFLSTGDVKSAEDETIWWVPLGIEGVCGTDGVSSLALTSKEDTISGVNTDFYKLNSNATGFFRVAYPPERLAKLGTQLDRLSVEDKITILGSASELAYAGRLPTSALLSFAKGFKEETNTLVWSQVLDSTSRAKFVFAEDPVIKAGLEKFILDLIDDAVTKIGWEFSEGEGYLQSQLRKRLIGSAVANNHPAVIKEALKRFNQWVEDPSSSAIHPNLRGAVYLAAIKDDPARAVETIKNEWFNTKSIDGKIISLSSLGSARNVDVIEKTLLPFLFDQSPPAAAKDSVPSADMHALGSSLARNPEGRLSQWKYIQENWDKCLAKLGNPIVVDRFIGVALSGFSNDKYIDEITAFFADKDTSSFNRTLETAKDGIRARSTYKKRDSAALKEWLIQNGFAKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX24</accession>
    <name>A0ABR3YX24_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mannose-1-phosphate guanyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GDP-mannose pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">GTP-mannose-1-phosphate guanylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Translation initiation factor eIF2B subunit epsilon</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">eIF2B GDP-GTP exchange factor subunit epsilon</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">GCD6</name>
        <name evidence="13" type="ORF">Cpir12675_004386</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="10">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-2B gamma/epsilon subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000122">
        <property type="protein sequence ID" value="KAL1892803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04197">
        <property type="entry name" value="eIF-2B_epsilon_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11558">
        <property type="entry name" value="W2_eIF2B_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035543">
        <property type="entry name" value="eIF-2B_epsilon_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051956">
        <property type="entry name" value="eIF2B_epsilon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056764">
        <property type="entry name" value="LbH_EIF2B3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044123">
        <property type="entry name" value="W2_eIF2B_epsilon"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45887">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45887:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25084">
        <property type="entry name" value="LbH_EIF2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00515">
        <property type="entry name" value="eIF5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5 13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="12">
        <location>
            <begin position="536"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="707"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="710"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1892803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="732" mass="80499" checksum="F3D7C477BB9B3C56" modified="2025-10-08" version="1">MSSKGKNASKAKKSKAETKAEDVLQAVILADSFQSRFKPLTLDRPRCLLPLANTPLIEYTLEFLAMNGVQEVYIYCGNHVDQVEKYIAESRWAPNSLRSPFTTISFVRITDARSTGDILRDLDKRGLIDGDFILVHGDLVSNISLEKALAAHKARRTENSANIMTVVLRTAGSVPHRSQAPAITPVFTVDTKTRRCLTYDEISATQETDNHHRLLLDYDLLGELSTDYQVRSDLIDPEIDICTPDVLALWSESFDYELPRKNFLQGVLKDWELNGKAIHTEILDSGYAARARNLSMYNAISRDIMGRWTFPFVPDCNLFPGQNYHADIRHGNVIELGAQIDATSKVSQSVVAGKTVVEPKAVVLGSFIGRGCRIGKGARIENSHVWDGTTIEEGAVILHSLVAGNGAKIGKNSALSEGSLLSFGVCIGEGSVVPSDTVLALEKHTNGRKGDPAVVGSESNAAQYVDPEDEDLDEDDPALTLKTLVYRPRRDSLASISTIHSYKSDSEFDDDESGDFKSHGSRQRLYSFTSDGSGSRQDTGFHGDAVQGLLDTLRGEGGDFDAAKLEFMGLRLSQNASDIAVRKAIATAFAYRAAELVEESGLEPTKAVERALTGRPGSAKFLDDVGVGSPQMADQRDLSLALHRAFSSLRTVDVARRGVLLSATLQKLYDLDIIEEDAILAWWADEKSQSDDLTPVREKCKILVEWLQTAEEEDSEEEEEDESEDEDEDEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXS9</accession>
    <name>A0ABR3YXS9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_004486</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000128">
        <property type="protein sequence ID" value="KAL1892558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507:SF1">
        <property type="entry name" value="FI18259P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507">
        <property type="entry name" value="ZGC:174356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="238"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="273"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="311"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="335"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="369"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="407"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="1"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1892558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="439" mass="47896" checksum="070B6EAFDA93B854" modified="2025-10-08" version="1">MAMLPMLRLLEDAVCHQVREDTSRGLLDETLCKTEEVQARLGYLVGWQQVAEGVVSIAAAMPYGILADRVGRKPALLLSWCGMIPGFAYIMGFIYLARDRNLYFVLVGSLFQVFGGGLSVAFSTIYAVASDVTANQNRATSFFYLAISATLGGISGPPLAGKIMMLYGPWAPIFVVLALSPPIIVLILLLPETLPQPALPPQKQAFSSSISRSISALSTSFHELLPSLQLLCNRNIQLVMAVFFLQTPIYIAYSTIMVQYVSHHFGWTIARTSYLFIPLGLLNILCLASLPRLSRELRTRLRLSAWRRDVALTRVALGLVAAGALIEWASRNVEWFMAGLVVGTVGSSNNPLARAVATRYMPREDTSRLMALIGVVETVGSFFGGPVLALCFEIGLAKKGWLTGLPYLYIAGLCGATLVGLGFLHRPVGREEECEDEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY60</accession>
    <name>A0ABR3YY60_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_004620</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000135">
        <property type="protein sequence ID" value="KAL1892264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF51">
        <property type="entry name" value="NUCLEOLAR PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="184"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="265"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="101"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="112"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="164"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="294"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="343"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="374"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1892264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="387" mass="42958" checksum="6A65E1851A3E2FBD" modified="2025-10-08" version="1">MAVKRRREDDEEVAAATSAAYDLENSIGTKPKKSKKDKKDKKDKKDKPFQSKAVKAKLKAKNDEDAENAEDLEVATAGDKDDGAAVLEKPADQTKQQLSKKQLKKLEKKVKKANEISEKDAIKTTEREKKKAEIAQDTKAEEEVRIDDAAEDIIKIDGDTGGENAEDTDENQDEEHEKKKNERFIVFVGNLPFTAKEEHLRKHFASLEPLSIRLLTSKLDPTKTRGIAFIEFSHWRSMRTCLDKFHHSTFDDGLSPARKINIELTAGGGGKTAHRTAKIKAKNDKLRASRSRRIQRESDERSQRKEKEDIEAAETARETGMHPARLAHIKEGGAPETNSNNSGNGGRFGGRGRGGFGGGRGRGGFGRGGGGRSGGDRDGRDFKRQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYG7</accession>
    <name>A0ABR3YYG7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mannosyltransferase ktr4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">KTR4</name>
        <name evidence="5" type="ORF">Cpir12675_004146</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000111">
        <property type="protein sequence ID" value="KAL1893408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002685">
        <property type="entry name" value="Glyco_trans_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121">
        <property type="entry name" value="ALPHA-1,2 MANNOSYLTRANSFERASE KTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121:SF7">
        <property type="entry name" value="MANNOSYLTRANSFERASE KTR4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01793">
        <property type="entry name" value="Glyco_transf_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="396" mass="46547" checksum="BE1210FABE3FD5D6" modified="2025-10-08" version="1">MVLARPVRVLALLAIITWIYIMFSVFKPSVSSIGNGGLNPQEYHLNDPMLDPYDEPEGPLHRTGPNYAPNSANSDRINATLLALVRNEEVADMISSMQDLERTWNHKFNYPWTFFNDVPFTSEFKKQTQAVTKAECRYEVIPKEHWSVPSWIDENLFEDASSTLESENVQYASKISYHQMCRWNSGMFYHHPALKDMQYYWRVEPKVNFFCDVDYDVFRWMQDHNKTYGFTINLYDDPKTIRTLWPETLKFIADHPEYINQNNAMKWLTDDIERPDHAAGTGGYSACHFWSNFEIGDMNFWRSKAYEDYFNHLDRAGGFFYERWGDAPVHSVALGLFEDASRIHWFRDIGYRHIPFFNCPNSPKCKGCKTGKMFDGENFLLKEDCRPNWFKYVGTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZE9</accession>
    <name>A0ABR3YZE9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004134</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000110">
        <property type="protein sequence ID" value="KAL1893435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42345:SF2">
        <property type="entry name" value="HELICASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42345">
        <property type="entry name" value="TPR_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="474"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="654"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1078"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1294"/>
            <end position="1313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="206"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="490"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="655"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1082"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1296"/>
            <end position="1309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1548" mass="169939" checksum="6ED990CA3DB821CC" modified="2025-10-08" version="1">MGFTRMPLDQYRKNSDVEDWINSNTAPARHELNSEQHYRQRPRQMESWVAPGAPSPQIRQMMSGSANSSSVGPMNYVSPSSFRAIAPPPITTTNLISSPALQQQDEPISSASPWGAFTFNHRRQYAGSDENLRGTANYYNNVSTPSITSPLSQIRTNEERSPFSEIRENDYTTEMSYSQEGGSAKEKSGSKRAGSFSATRGREILSSMFSSKPSVSSLSSAASRDRRSQSRHRDQAGDQVDTNNTKTDIEINTAVPSPRNPEHRNTIPTMSQPQKSHSAPRPEAIGTAAPSRSSMPHGMLSSILTSRHSASSMAATSGSRSNITSAPAAIHPQTIRSSRTPISRCHTPTEYMSNPGMSRKTSFPTMVPHMSSRPMPGPISMPPMAMSGFQHPNAPIMSPMAVSTPLTPRMPSPMAARPDTATSQGPTMWLASPDAQTPGGIGLVPLNPTSMTMCTGSGARDYFSRTESTVIPLQTAYTQMTPPPGSYYDSPASESPSSPFPGASSKRKPLFDFNKPLPTPPRSNSIRSQDARRLNIQRIMTTLGEDDVEKLFSGAPQFFARSEGHNTGAPHPSAAYPWDEELAIRDMSDHMRIGDPAWSCMTAWPHIPVRIRSEPSNGGLGIDYRLERTLSNGSGNRESGSDFASLGSPIDDYSHPLSRTSTSSSSINPLSPVVSHAPPPEKKRGHYFPRCREKPSMLNMQGLEKGTMGYQSALEFGVADALSQDQSGFDIHRLPRGPEVLNARKRLLAARDGLRALDEHVILNQLSVDCQRYRDPKFWGNKRGPSPTDSKLPNNKVLYNELYTTILNPPLKYADTADKGSLAPQIRSLVQTLALPNIWIDFSRVEWRLQIGQILWGLHREDAVDEASGSDPESTFNAQQPIHAEERTWLLAQILLACELLIRLDSITEDEELGLENIPINSVRRFEKEATTPVKWSLMLARSFMENVDISIEEPAVNSPATHNSNHHHEAELHLTVTDGTSTNERSLGGWLAGLTKKMSLHHRHDSYCKGPVYSIKGRFADRQVYGLLHFAKILRWPGMDEYERRIMENCLAADDNIPGISSHRSSMASDAVTAVPKQPAASVSQPSTVKKTNIPSRRRHVSATLHEAGWLSKIYMSGIILAGESLGYIIMATLLENDPKALRQIGNRANLSGGFVWKNKSFWNTANVVGRVLAAGKGSAQCLSWISSDVVPVGHTAGWIDVVSHEVKDDLDKTGKKARLWQKHDIEKASNVIGNADEKSVLPGDFIIPYEDVYMLPPDHVNTTLHSIEAPQIKPHLNGDNFQDSHLAPDHVQLSSGVTTSSPSPSESKQGITSMPACMRFAVNLGNDVQREVKVTLEYDIDFVTAHPCAPSQHVRFVRSSTNTSIQQIDVSGFGIPGKVTTPAVVAGHPLHRSFTYTIMHISDLLRRPRDNNLDDLLLAASTSQNRKPSQMPPSSQDGTAPRVLIIDCITNQNRTQILFSSSASQNSADFAPSSPTSPVMSRKGELPMMHAESRGRQFGSDLEVLARAICAQKGWNALVSRKRRGCLSCAIREAEALAWKVVIRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0C0</accession>
    <name>A0ABR3Z0C0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Inosine/uridine-preferring nucleoside hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_004042</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IUNH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000106">
        <property type="protein sequence ID" value="KAL1893654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="entry name" value="Ribonucleoside hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023186">
        <property type="entry name" value="IUNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304:SF56">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G11790)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304">
        <property type="entry name" value="INOSINE-URIDINE PREFERRING NUCLEOSIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="Nucleoside hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inosine/uridine-preferring nucleoside hydrolase" evidence="4">
        <location>
            <begin position="6"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="428" mass="46881" checksum="DB49CFAB9D1A0DEF" modified="2025-10-08" version="1">MAPHKIIIDTDPGVDDILALLLAMASKPEEIELIMISVTYGNVPLSSCLKNAVALFHVLEKEFAWRRSVGRAEGYESLKACKPILAVGPDHPLEEESLIADYFHGLDGLHGVHEKHPDLSPADTWKDLFEGGAEAASENNHLFAPSKVPAHKELLRLLRENPADSVTLLTIGPMTTAALAASEDPETFLKLKEVVVMGGAVHVPGNITPVAEFNTYADTIAAARVLALTSAKPASTMPVLPNELSKLPPYPESLPRKLNLALFPLDITTPHLLMRDTFDAVIKRQIEAGSPLAIWINHFLSKTLDHIESFVGPDEIPGLSLHDPLTVWYMITHNDPGWKTTPKPEDIRVETTGQWTRGMHVIDKRGRKRAEDVILTPATSTAPAITAEEIPNDDNGWLSAVRGNRVNRYISSPGEMDFAPFMLGRIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1G0</accession>
    <name>A0ABR3Z1G0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ca(2+)-dependent cysteine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MCA1_2</name>
        <name evidence="7" type="ORF">Cpir12675_003688</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000091">
        <property type="protein sequence ID" value="KAL1894459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050452">
        <property type="entry name" value="Metacaspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104:SF30">
        <property type="entry name" value="METACASPASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104">
        <property type="entry name" value="METACASPASE-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="Caspase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="Peptidase C14 caspase" evidence="6">
        <location>
            <begin position="118"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="74"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1894459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="413" mass="44357" checksum="DF2BB459B78EAF96" modified="2025-10-08" version="1">MYGYPGSGHGPHGGGGGHGPPFGAPPGGYGGPGGYNGGGGYPQQHQQYAPPSEAPPSWLDRFGMPFGQGQNNQGYGGSGGYGGGNGQPRAEMPPTESQKFGHGAPDDYSFKYSNCTGRRKALLIGINYFGTEAELRGCINDVHNVTNFIMQNHGYKREDMVILTDDKTNDPMSMPTRENIIKAMKWLVAGAEPNDALFFHYSGHGGQAADTDGDEEDGHDETIYPVDFQRAGHIVDDEIHEYLVAPLQAGVRLTAIVDACHSGSVLDLPYIYSTKGVIKEPNLAKEAGEGLLSAFKAYSRNDMSGVATEVFGFIKKAAKGDGAYKKTIKTKTSSADVVMWSGSKDDQTSADATINSKATGAMSWAFISSMNNNSTQTYLELLNSIRDLLEQKYSQRPQLSSSHPLDVNLKFVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1J6</accession>
    <name>A0ABR3Z1J6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7492 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003824</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000097">
        <property type="protein sequence ID" value="KAL1894089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055915">
        <property type="entry name" value="DUF7492"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24320">
        <property type="entry name" value="DUF7492"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047286663" description="DUF7492 domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7492" evidence="3">
        <location>
            <begin position="19"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="396" mass="42794" checksum="BEB69E25DA94F217" modified="2025-10-08" version="1">MQPRAVLATLFCFASMTLGHTWVEMLMRISSKGAMIGIPGYPRGYVARSDPGFNDKEVLYQLPTPGTNGLISQTAPISKFSSDKYTADRPMLQAFPGEFIAMRYQENGHVSLPKNSPNKPLNRGTVYVYGTSQPSDDDTLLNIHKVWNLEGTGGDTRGVLLSTRHYDDGRCHQTNKGPISTDRAAKFPKTADNLQGTDLWCQTDVQLPSNLDIGSVYTLYWVWDWPTLDPALINIQDTANGNYPTQGGSVKIPEVYLSTADVKIVPESSLSARGDIQVMAATASNTSPDTIGNAAIPEQLSNLFQVAVNSSSNNGSDGDKGVPTTTNPTVLPMPIKPSATFVPSTFSMTTRSRPASNPTGKKLVTVTAAPVYVTSTVTIALHTQAMSTIIQRFSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1W1</accession>
    <name>A0ABR3Z1W1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nucleolar protein 58</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">NOP58</name>
        <name evidence="9" type="ORF">Cpir12675_003718</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for pre-18S rRNA processing. May bind microtubules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOP5/NOP56 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000093">
        <property type="protein sequence ID" value="KAL1894290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.4070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.90">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045056">
        <property type="entry name" value="Nop56/Nop58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012974">
        <property type="entry name" value="NOP58/56_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042239">
        <property type="entry name" value="Nop_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002687">
        <property type="entry name" value="Nop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036070">
        <property type="entry name" value="Nop_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012976">
        <property type="entry name" value="NOSIC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894">
        <property type="entry name" value="NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894:SF1">
        <property type="entry name" value="NUCLEOLAR PROTEIN 58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01798">
        <property type="entry name" value="Nop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08156">
        <property type="entry name" value="NOP5NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00931">
        <property type="entry name" value="NOSIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89124">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51358">
        <property type="entry name" value="NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Nop" evidence="8">
        <location>
            <begin position="293"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="465"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="478"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="492"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="545"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="568"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="578" mass="64300" checksum="B6F2021C7903E7EE" modified="2025-10-08" version="1">MPLYVLSETPAGYGLFKSADKKLHTRDDVSAKLASLEAVSEMFKLKDFRKYESTSMALEEVASMSSRNVKVPQLLADFLQEVKGEKHASLALADKALGQKLKELPGFEKLDIVAASDSAAGRGVEEIFRAIRENMNALMPETSSTFERVALGLSHSIDRHKLKFTEDKVDSMIIHAVKHLEDLDQSLNVMAMRTKEWYGWHFPEMSRHIADNVAYARVIIETGTRDTFATADLTTVLPEPMADAVKAAAEISMGTDVDKDDMENIKLLARQVVTYSEHRTELATYVENRMRAIAPNLTALVGYLVGAKLIAHTGSLLNLSKSAASTIQILGAEKALFRALKTKHNTPKYGLLYNSSLVGQASMKYKGKIARMLAAKTALGLRVDAMKATKMNEDGEEVIDDEYELDEEERAFFGLNLRTKLENKLRSLEGKPLLPKGVNVGPDGQALQPGEFTIREKRAYNMDADAVAETPKKPLIQEVEDTPMDDDSSSESEDKPKKLSDKEYERLAEQAGISVSKFKRKYERGDVELNADGSIKVASKKDKKKEKNEGESSKRKRDDNATPTKTEKKQKKKKTAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2P1</accession>
    <name>A0ABR3Z2P1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">[NU+] prion formation protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">NEW1</name>
        <name evidence="11" type="ORF">Cpir12675_003508</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000084">
        <property type="protein sequence ID" value="KAL1894813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18626">
        <property type="entry name" value="CD_eEF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015688">
        <property type="entry name" value="eEF3_ABC2_chromodomain-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047038">
        <property type="entry name" value="eEF3_chromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF14">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24984">
        <property type="entry name" value="HEAT_EF3_GNC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24987">
        <property type="entry name" value="HEAT_EF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0034">Amyloid</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0640">Prion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="HEAT" evidence="8">
        <location>
            <begin position="212"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="471"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="716"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1036"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1036"/>
            <end position="1048"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1894813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1103" mass="121004" checksum="41794318DB9B2E37" modified="2025-10-08" version="1">MTVSELPLMVAPGAGPTPSEEEVAGIITTIFNAQSSQASVEASYALCELLLNSVGYAGLTQYGIIAEVKKAAGDKKSGLRRESAQNLLGAIFERFPPRAPISEVLFLIQDGGILNIALDALADKGSVVREAAQYGIDALFNNLGGEAMVVGLLPALTCYLSKKTGKWQGTVGAYALLQKMADKAKMEIGVSKEVSDEKDILREAMGAKLAILIPIVEEGMHDLKSEVSKQAVTTMSTLTTLLSNDDVAPRIPLLLNSMQNPSSDTLQKAIHALSMTTFVAVVTSPVLALLTPFLERSLNNPSTAQEVLRQTVVVTENLTKLVHDPIEARTFLPKLQPGVKGVVDRASLPEVRELASRALETIHKAMGDDNNIASRTTAADVATVVEAGLKKYDVSDVKNTDGYKLVNSYFCEQVTEGVNHRQLERLAKVVAPYLQHLTPKAAEVAAFVHEHYVTEDRIKHGQPPQDEEGEMEIVNANFSLAYGGMLLLSHTNLRLLKGHRYGLCGRNGAGKSTLMKSIAGGKLEGFPSQDVLRTCYVEHNQGEDAEISILEFVIKDHEIAAAGRERIVAVLEEFGFDSGPEGRQSQPVGSLSGGWKMKLALARAMLQKADVLLLDEPTNHLDVANVKWLENYLQTHPDITSLIVSHDSGFLDAVTTDIYHYEANKKLALYHGNLADFVKVRPEAKSYYTLSASAVQFKFPPPGILTGVKSNTRAIIRMTNASYTYPKAPKPSLSDVSCQLTLSSRVAIIGPNGAGKSTLIKMLTGEVISSTGKVEKHPNLRIGYIKQHALEHVEMHLEKTPNQYLQWRYQHGDDREVHMKQTRIMSSEEQAQMDKPIDIGDGKSPRQVEALVGRQKLKKTFQYEIKWRGLMPKFNSFMSREKLIELGFSKPIQEFDDHEASREGLGYRELQPKVISQHFQDLGLDPEIANHNEIGSLSGGQKVKVVIAGAMWNNPHLLVLDEPTNFLDRDSLGGLAVAIRDFKGGVILISHNEEFVGALCSEQWHVNHGRMVQKGKAAVSMDRFEDNSAVASAMTSAAPSTAPSTVPSGAEDNSEMKFKARKKKKMTKKELKDREARRRLRHIEWLSSPKGTPRLPDTDDEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2Y1</accession>
    <name>A0ABR3Z2Y1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cysteine desulfurase</fullName>
            <ecNumber evidence="3">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">NFS1</name>
        <name evidence="13" type="ORF">Cpir12675_003444</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters. Plays a role in both tRNA-processing and mitochondrial metabolism. Involved in the 2-thio-modification of both 5-carboxymethylaminomethyl-2-thiouridine in mitochondrial tRNAs and 5-methoxycarbonylmethyl-2-thiouridine (mcm5s2U) in cytoplasmic tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(sulfur carrier)-H + L-cysteine = (sulfur carrier)-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000081">
        <property type="protein sequence ID" value="KAL1894985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00331">
        <property type="entry name" value="Cys_desulf_IscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010240">
        <property type="entry name" value="Cys_deSase_IscS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02006">
        <property type="entry name" value="IscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010611">
        <property type="entry name" value="PRK14012.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601:SF34">
        <property type="entry name" value="CYSTEINE DESULFURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601">
        <property type="entry name" value="CYSTEINE DESULFURYLASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="12">
        <location>
            <begin position="76"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00045623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00050776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1894985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="476" mass="51920" checksum="717E843666F859D9" modified="2025-10-08" version="1">MTHTPAALVAAQRRLVSSSRQDSAQVQTEAAAAVKLGAHDVTTSASASSGGVQEGDHENAMADIMKDASKEEGRPIYLDMQATTPVDPRVLDAMLPYYISVYGNPHSRTHAYGWESEQAVEEARGEVAALIGADPKEIIFTSGATESNNMSIKGVARFFNRSSKKKNHIITTQTEHKCVLDSCRHLQDEGFEITYLPVKKGGLIDLEDLRAAFRPETCLVSVMAVNNEIGVIQPLAEIGKMCRERKIFFHSDGAQAAGKIPLDVNAMNIDLMSLSSHKIYGPMGIGACYVRRRPRVRLDPLITGGGQERGLRSGTLAPPLVVGFGAACRIAREEMAYDTKRIKTLSDQLLNGLLAMEHTSQNGDPNHFYPGCVNVSFAYVEGESLLMALKDIALSSGSACTSASLEPSYVLRALGNSDESAHSSIRFGIGRFTTEEEIDYVLKAMQERVTFLRELSPLWEMVQAGIDLNTIKWSQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z407</accession>
    <name>A0ABR3Z407_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cytochrome b561 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Cpir12675_003267</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000074">
        <property type="protein sequence ID" value="KAL1895360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08761">
        <property type="entry name" value="Cyt_b561_CYB561D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045150">
        <property type="entry name" value="CYB561D1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15422:SF45">
        <property type="entry name" value="CYTOCHROME B561 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15422">
        <property type="entry name" value="OS05G0565100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03188">
        <property type="entry name" value="Cytochrom_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00665">
        <property type="entry name" value="B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50939">
        <property type="entry name" value="CYTOCHROME_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="144"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="216"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="13">
        <location>
            <begin position="41"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1895360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="243" mass="26317" checksum="8FD951224AC1132A" modified="2025-10-08" version="1">MPSSGIEQTGNTETGVPQNEAVPLLGDRGDAAQPIGDSMAHNLVLGTGILAQIANVLFLLTIWATILLGDVILFSGHPLAASVGVFSLIQSILVLQPTHTASQKRTGQRYHAAFNTLTFLGVGLGIGIIEYNKVKNRMPHFHSIHAYFGVITGVFMAVQFLVGVTMWAVPSLYGGEQQAKSIWKYHRMSGYALLLLVLATIVSATRTDYIVRVAEIKTWSIVFLCVFIVAGIFPRIQRGKLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6C1</accession>
    <name>A0ABR3Z6C1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Mitochondrial ornithine carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ORT1</name>
        <name evidence="13" type="ORF">Cpir12675_002905</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000062">
        <property type="protein sequence ID" value="KAL1896198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF31">
        <property type="entry name" value="MITOCHONDRIAL ORNITHINE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="24"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="125"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="238"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1896198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="330" mass="36251" checksum="445D4A59CA6F0E7F" modified="2025-10-08" version="1">MDALTRQKSNDDFSPSPEPSSGAIRVVEDLAYGSAAGIVGKLIEYPFDTVKVRLQSQPDHLPPQYKGPIDCFKQSIRADGVASLYRGISAPLVGAAVENSCLFFFEGLGRSLMYDYGFIGKNEPLALGALWATGAFSGACTSVVLTPIELVKCKIQVPDSSSTTAKQSLRPMSVISEIYRHSGIRGFWNGQMGTLIREMGGCAGWFGAKETVSELFYHRRERLERVSGQAVSPRTKALPLWQQALAGAMAGVTYNFLFFPADTIKSRMQTAPMTPGVQPRSFRQEFLAVWRQMGIRGLYRGCGITCLRSAPSSAFIFMVYDGLKRYFPMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6M4</accession>
    <name>A0ABR3Z6M4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Vacuolar transporter chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">VTC4</name>
        <name evidence="9" type="ORF">Cpir12675_002916</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000062">
        <property type="protein sequence ID" value="KAL1896208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07751">
        <property type="entry name" value="PolyPPase_VTC4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14480">
        <property type="entry name" value="SPX_VTC2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.100.30">
        <property type="entry name" value="VTC, catalytic tunnel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051572">
        <property type="entry name" value="VTC_Complex_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018966">
        <property type="entry name" value="VTC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042267">
        <property type="entry name" value="VTC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140:SF1">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE COMPLEX SUBUNIT 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09359">
        <property type="entry name" value="VTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="721"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="748"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="790"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="8">
        <location>
            <begin position="33"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="67"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="553"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="74"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="564"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1896208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="817" mass="92869" checksum="3D5B401500C83198" modified="2025-10-08" version="1">MLVIEDLKTRKTIWKSNHTGHPIPKVPPGFIVMKFGEQLRTSVIREYEWSYIDYEGLKNDLLDGARRRGSSTARDTKGKGKAQDKSPAAQGWSEDDEARFVAKLDAELDKVHTKQKVKAMEISRRIQLSEKEVGEVVGRLNERTVGEDAPSEEEFMLLEQDLSDVIADVHDLAKFVQLNYTGFYKIIKKHDKLTGWHLKPVFDVRLKAKPFYKENYDAQVVKLSKLWDLVRTRGNPVKGDSAAGGSQGSFVRQTTKYWVHPDNVTELKLIILKHLPVLVFNPNKEFETADSAITSIYYDNPETWELYEGRLKKTEGAEAIRLRWYGGMKTDTIFVERKTHREDWTGEKSVKARFGIKEKNVNAYMRGEMLPAALFEKARKERKKPEKAIAEDQRLAAEIQYEVLKSGYKPVCRSFYNRTAFQLPADARVRISLDTELTMVREDNLDGCMRSGDNWRRMDIGIDWPFSQLPAGDVERFPYAVLEVKLQTQMGQEPPEWVRQLISSHLVEAVPKFSKFIHGTATMFPDRIKLLPFWFPQMDVDIRKPATHDFGIKRPSIEAAASTSDDDDDFASDDDDDLPATSRSGQGHGQGLRMLAANPIANGDAEGQVSETPAANDYIYDSEDEYDEDYALEESRRIGGITYYAAVTKSMIRRVGSAVKTTMSNMVPASRGSAIPRNDRLRMLYGAQEIQSKRFKAPKGKKIHVPVRIEPKVYFAAERTFLGWIEYSIYIGTIAVTLLNFGTKPTAASFIVSGTFTIIAIFALLYSVGIYLYRSEAIRTKRVAKYYDRWGPSILCGCLFTAVALNFGFEGRERGVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6Q7</accession>
    <name>A0ABR3Z6Q7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">14-3-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003202</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 14-3-3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000072">
        <property type="protein sequence ID" value="KAL1895513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.20">
        <property type="entry name" value="14-3-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000308">
        <property type="entry name" value="14-3-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023409">
        <property type="entry name" value="14-3-3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036815">
        <property type="entry name" value="14-3-3_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023410">
        <property type="entry name" value="14-3-3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18860">
        <property type="entry name" value="14-3-3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00244">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000868">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00305">
        <property type="entry name" value="1433ZETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00101">
        <property type="entry name" value="14_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48445">
        <property type="entry name" value="14-3-3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00796">
        <property type="entry name" value="1433_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="14-3-3" evidence="3">
        <location>
            <begin position="4"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="230"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="244"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="257"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1895513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="273" mass="30180" checksum="99C0E8EE1FF8F7C7" modified="2025-10-08" version="1">MATETFLARLCEQAERYDEMVTYMKEVAKLGGELTVDERNLLSVAYKNVVGTRRASWRIISSIEQKEESKGSEKHVPVIRDYRAKIELELEQVCQDVLDVLDQFLIPNAATGESKVFYHKMKGDYHRYLAEFASGEKRKGAATAAHEAYKSATDVAQTELTPTHPIRLGLALNFSVFYYEILNSPDRACHLAKQAFDDAIAELDSLSEESYRDSTLIMQLLRDNLTLWTSSDGAEPEAGDKAAADASPEAGAAAAEGETKEETKEETAPAAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z720</accession>
    <name>A0ABR3Z720_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1868 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002813</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000059">
        <property type="protein sequence ID" value="KAL1896409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="LigT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="332" mass="37410" checksum="D2F39DF33A67A249" modified="2025-10-08" version="1">MAYDRPNEVIADLSGLNTSNDLNPFRAFIVACSDNAAQVQAAYDSHRTKRNAAQKVKFLAEGTKLSPDLTLRRMLKLNVQDERNCLTVWSRPPTHIIDVARKVQEMIVKGIPDAWEYWLMPTHNMHMTVAEAVFSQPPEVIQDFVRLLRPHAARLARTTYTHRARLVRPLLSMDTSAFALSFVPACNEPFLASQMDAMTAEPPIDEEGGENNGRENTNTGDAYTYHHLRRDVFSRLLDAGITPTPRYQVPSAHITLGRFVGAGNQPAITRADAEQWIRCVDNINTWLCETYWTSEDVHRSAEWIVGQERGLDIRYGPVWYGGGKSLVVGEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z761</accession>
    <name>A0ABR3Z761_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA mismatch repair proteins mutS family domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_002774</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000057">
        <property type="protein sequence ID" value="KAL1896485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017261">
        <property type="entry name" value="DNA_mismatch_repair_MutS/MSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF20">
        <property type="entry name" value="MUTS PROTEIN HOMOLOG 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="5">
        <location>
            <begin position="571"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1896485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="758" mass="82781" checksum="78D4EF3441967673" modified="2025-10-08" version="1">MNSLGSIYERCNGKAKVLFSTSNLAGYDSASLLRLSSAINPESRISIGCAGAVVSDIRRRCEVAIITNDHEVSKISMFTLKDFMFVNLDSMVSLQIINSEMHPNSLIWGPQNPSTGSKESLSVYGLFHSLASSSLGKLKLRKLFLRPVLDMHVINQRQQTIGLLVRPENQDILYSISKALRGVKNIRSSLEQLKKGTDPVMGRGSSDNGVWGTVQKFCSSVTKIREIVSRVSGSNLPPIIQSTLEAIHSPNMHAVGQMISHTVNLERSQPVSRAVVAEGVDTQLDELRRTYDGMESLLNEAAQHMIGTIPSWARDCISNCIFYPQLGFLTVIPINPDTNTARYSGEGMPDSEWEQMFAADGNAFFKNNAMRELDAQFGDMYSMISDLEIEILHQLSLQVIRYEESLVAAGDACAELDCMIALALGAQKYGWTQPTMTDENVIQIKGGRHPLQELVVPVFISNDCNLAGGIGKDSPIDSGSAIVSESGDPPRTLVITGPNHSGKSVYMKHVALIVYLAHIGSFVPAKSAVIGITDKILTRISTRESAGQNQSAFTIDLQQIAFAARMATRRSLVLVDEFGKGTRADDGAALLAALIDHFAAYGVEAPKMIVATHFHEIIQGGYLKSCPGINLAHMEVRDMKDKAANSQDRVIYLYQLQEGPSLSSFGAICASLNGVDDKVVQRAEALMASMSLNKDLRSICSEMTAEEQFKFEVAEEAARGFLRLPLDSIDLIGDKTMHATDVIRGLLQDTLKQRVGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7N6</accession>
    <name>A0ABR3Z7N6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 16 17">Phosphatidate cytidylyltransferase</fullName>
            <ecNumber evidence="6 16 17">2.7.7.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Cpir12675_002700</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 16 17">
            <text>a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-1,2-diacyl-sn-glycerol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:16229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.7.7.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 16 17">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 16 17">Belongs to the CDS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.41" evidence="6 16 17"/>
    <dbReference type="EMBL" id="JAWDJO010000055">
        <property type="protein sequence ID" value="KAL1896678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000374">
        <property type="entry name" value="PC_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016720">
        <property type="entry name" value="PC_Trfase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13773">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13773:SF8">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE, PHOTORECEPTOR-SPECIFIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01148">
        <property type="entry name" value="CTP_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018269">
        <property type="entry name" value="PC_trans_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01315">
        <property type="entry name" value="CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 16" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12 16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 16 17" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14 16" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="15 16" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 16 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 16 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="329"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR018269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1896678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="447" mass="50176" checksum="8ECF32D9F835F076" modified="2025-10-08" version="1">MARSRKGNKAGSHAGDASDDGSCSSPVQSHRSMAHSSNRAKPVAESKENQRQAEFEKKKANFFTRTLWTLIMVFGFVAALAAGHIYVIVIITVVQIISFKEVIAIANVPSRARQLRQTKNLNWYWLATTMYFLYGESVIYYFKHIVLVDKVLLPLATHHRFISFVLYVFGFVFFVSTLQAGHYKFQFTQFAWTHMALYLIVVQAHFIMNNVLEGMIWFLLPATLVINNDIWAYICGITFGRTQLIKISPKKTVEGFIGAWLMTNVFGVFTAKLMMRSGFFICPVTDLGANVFTGLDCVPNPAFVPKVYSLPQFVFLPPGFNFSFTTEPMMFHTLALATFASLIAPFGGFFASGLKRTFKIKDFGDSIPGHGGMTDRMDCQFIMGFFAYMYYHSFIAIHKASLGSVMETAITGLTVEAQIELVRGMAKHLNNQGVWGTLECLSDSMTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7P8</accession>
    <name>A0ABR3Z7P8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Macro domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002708</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000055">
        <property type="protein sequence ID" value="KAL1896686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02908">
        <property type="entry name" value="Macro_OAADPr_deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="entry name" value="Leucine Aminopeptidase, subunit E, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002589">
        <property type="entry name" value="Macro_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001664">
        <property type="entry name" value="PRK00431.1-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11106">
        <property type="entry name" value="GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11106:SF27">
        <property type="entry name" value="MACRO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01661">
        <property type="entry name" value="Macro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00506">
        <property type="entry name" value="A1pp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="Macro domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51154">
        <property type="entry name" value="MACRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Macro" evidence="1">
        <location>
            <begin position="35"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="226" mass="24212" checksum="5CDD25E77B490C0F" modified="2025-10-08" version="1">MQNLDYSSANTVLHISDIPTLPQLYSGGRLGTTIHPLRTPCLEYNHKVAHICADITLIEADAIVNAANCELSGGGGVDGAIHRAAGPELAAACEVLNGCKTGESKITPGFSLPARHVIHTAGPIYGRRENKESDRLLGSCYSNSLNLAVENGCKTVALCAISTGVYRFPSDSAADIATRTVRQFLEGGHGKDIDKIVFVSFEAKDADQYQKHLPKYFPPTKNDSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8H2</accession>
    <name>A0ABR3Z8H2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000057">
        <property type="protein sequence ID" value="KAL1896472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="462"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="495"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="526" mass="62928" checksum="0E8860DAB09CB7AF" modified="2025-10-08" version="1">MSHYTSDSDSDKYVESRHHRRTHNRNDGYYYDLNTCQFHQSGPADIVYTSDDDDDSETDYFKSTDSWHSGRHSPVSPAITHFPPEAPVVYNTVVNNKFSDDEHSSHDRHYQVQRKPITHNSHENQIKLDDQGILEKCKLDSQKLEEALMHERHVLEERIRLEKIAMKDRMDATTSSLELERLKREQEKKREAARREKERLEAEELRLARQKLAEIERERERIENERRRTESASLHRARVELNAINHHHEKELEEKRRKEEESLRRAKETLDELNRRKEAEEAERRLAESLELRRRKEAEAAEREQKERKEIENWAIEQYKLKEANRIKLEAEEKERFDREIKRGLEERLAASGLDNKTIASIVSGKKVELDHECEHASDHKDHDSALTTYQDQRAGDYLAQILQPTYTRMHRSYISVKTLIAFNIDFLFDQDPNYIIITREVPEWERACLWEHTSTLREEHSSYYDKKRYRSTSRGREQYRHHRHRSYSRTRKYKISDNTKEQASHKRNHSKPRSPSLLMFLAGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8P2</accession>
    <name>A0ABR3Z8P2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">NADPH:adrenodoxin oxidoreductase, mitochondrial</fullName>
            <ecNumber evidence="8">1.18.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ARH1</name>
        <name evidence="10" type="ORF">Cpir12675_002782</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>2 reduced [adrenodoxin] + NADP(+) + H(+) = 2 oxidized [adrenodoxin] + NADPH</text>
            <dbReference type="Rhea" id="RHEA:42312"/>
            <dbReference type="Rhea" id="RHEA-COMP:9998"/>
            <dbReference type="Rhea" id="RHEA-COMP:9999"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.18.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ferredoxin--NADP reductase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.18.1.6" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000058">
        <property type="protein sequence ID" value="KAL1896445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055275">
        <property type="entry name" value="Ferredox_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021163">
        <property type="entry name" value="Ferredox_Rdtase_adrenod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48467">
        <property type="entry name" value="GLUTAMATE SYNTHASE 1 [NADH], CHLOROPLASTIC-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48467:SF1">
        <property type="entry name" value="GLUTAMATE SYNTHASE 1 [NADH], CHLOROPLASTIC-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000362">
        <property type="entry name" value="FNR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0274">FAD</keyword>
    <keyword evidence="3 8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 8" id="KW-0521">NADP</keyword>
    <keyword evidence="6 8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="9">
        <location>
            <begin position="37"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1896445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="503" mass="55955" checksum="508941D9D92A5AA9" modified="2025-10-08" version="1">MNRCKILMRQPLVRRLEPARLFHRYLSSSAAASRSFRLAIIGAGPAGFYTAQKVIACIPDAKVDMYERLPVPFGLSRFGVAPDHPEVKNCQDRFEEIAAHPGFTYIGNVSIGNPTGFPETSHVPLSAIIRNYDAINFAYGASHDRHLGIPGEEAYSGIHSAREFVAWYNGLPGFERDFGLSEAEDVVIIGQGNVALDVARILLTDADVLRKTDITESALEQLSKSRVQRVHIIGRRGPMQVRLTIKELRELMRIPGVHSHPIDKDLLPKKLKELPRQQRRLMELLHDPKTTSTGMEDKSWSLNFCLSPTNFIGQSGKVIKSVFQKTVLNDPFNPKSSCKNTGEEVHIDSDLVFRSIGYESSPLEGFAEAGIAFDRTKGLIKNDDVGRVYKEGAGNEVLPGFYCSGWVKCGPVGVIASTMSDGYLTAESIVHDWNKEAQFLGGHTSKGAWRGVMEEIESPERLRVVNWDDWHRVDQAERAQGLALGKHREKFTKTSDMLSVVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9P9</accession>
    <name>A0ABR3Z9P9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 15">DNA topoisomerase 2</fullName>
            <ecNumber evidence="5 15">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">TOP2</name>
        <name evidence="19" type="ORF">Cpir12675_002591</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14 15">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the type II topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="5 15"/>
    <dbReference type="EMBL" id="JAWDJO010000052">
        <property type="protein sequence ID" value="KAL1896942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16930">
        <property type="entry name" value="HATPase_TopII-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00187">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03481">
        <property type="entry name" value="TopoIIA_Trans_ScTopoIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03365">
        <property type="entry name" value="TOPRIM_TopoIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.670">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="entry name" value="Topoisomerase II, domain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="entry name" value="Topoisomerase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050634">
        <property type="entry name" value="DNA_Topoisomerase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001241">
        <property type="entry name" value="Topo_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013759">
        <property type="entry name" value="Topo_IIA_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013506">
        <property type="entry name" value="Topo_IIA_bsu_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001154">
        <property type="entry name" value="TopoII_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018522">
        <property type="entry name" value="TopoIIA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031660">
        <property type="entry name" value="TOPRIM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034157">
        <property type="entry name" value="TOPRIM_TopoII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10169:SF38">
        <property type="entry name" value="DNA TOPOISOMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10169">
        <property type="entry name" value="DNA TOPOISOMERASE/GYRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00204">
        <property type="entry name" value="DNA_gyraseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16898">
        <property type="entry name" value="TOPRIM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01158">
        <property type="entry name" value="TOPISMRASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00418">
        <property type="entry name" value="TPI2FAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00433">
        <property type="entry name" value="TOP2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="Type II DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52040">
        <property type="entry name" value="TOPO_IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00177">
        <property type="entry name" value="TOPOISOMERASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12 14 15" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="13 14 15" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 14 15" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="17">
        <location>
            <begin position="563"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="domain" description="Topo IIA-type catalytic" evidence="18">
        <location>
            <begin position="816"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1192"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1294"/>
            <end position="1768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="31"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1192"/>
            <end position="1203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="1204"/>
            <end position="1216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1353"/>
            <end position="1362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="1363"/>
            <end position="1375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1384"/>
            <end position="1406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="1417"/>
            <end position="1428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="1452"/>
            <end position="1461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1473"/>
            <end position="1484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1486"/>
            <end position="1509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="1524"/>
            <end position="1533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1620"/>
            <end position="1634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="1636"/>
            <end position="1663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1675"/>
            <end position="1700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="1711"/>
            <end position="1727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="1737"/>
            <end position="1748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="1753"/>
            <end position="1768"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="14">
        <location>
            <position position="906"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU362094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS52040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1896942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1768" mass="196565" checksum="1807CE5CBE36C3B4" modified="2025-10-08" version="1">MGFDFSDDSSFGAGDDRDVESDGFVPEKKKPATKTKAAPKKAAPKKTVQTTLTGGKISATKKRTQAFSASDDDDAPGLADTPPTSKKQKKGPAKKAAATSTLADIENASFMDEVEVPTTMSGKDKNASEKYQKLTLLEHVLKRPDTYIGSIEKTEQQMWVFNKSTGLMEYRKISYVPGLYKIFDEILVNAADNKQNDVSGQAPMTNLKVSIDREAGEISVENNGKGIPVLMHEKENMYVPEMIFGHLLTGSNYNDDEKRTVGGRNGYGAKLCNVFSTQFTIELQDSTNGKRYKQVWTKNMSQIGKAKITNSKSSDFVRITFKPDFVRFGMPDGIDDDLESLIMRRTYDMSGTIRGVKVFLNNEQIKIKNFVAYSELYAKAIAKEREAEEGGEPSTTVITDIDKSRPRWEIGFTVSDGTFQQVSFVNNIATTSGGTHVNYIADQITSSLLAHLDKKRKGHALKQNHIRNHIFIFINCFIDNPAFTSQTKEQMTTKMSQFGSRCQLSDSFLKKIQSSEAIAKIVSYAEQKADKMLAKSDGNKRSRINNSKLVDANLAGTRHGHECTLILTEGDSAKSLAVAGRAILDPDRIGVFPLRGKMLNVRDASLDQITKNQEIQNIKQFMGLKHKAVYTDTKSLRYGHLMIMADQDHDGSHIKGLLINFLQVQFPSLLKIPNFFREFITPIVKTWQGNNPKRPLRQRSFFTQPEYNEWLEIHKDDKPKWRYKYFKGLGTSSNDDAQVYFTNLDDHLKVFDTMKVEESSLFELAFSKKKADARKEWLGNFVPGTYLDHTTKSISYTDFVNRELILFSMADNIRSIPSVLDGLKPGQRKVIYACFSKNIVQDMKVVELAGFVSGHTSYQHGEVSLQQTIIGLAQDFVGSNNINCLEPSGNFGSRLAGGSDAASARYIHTRLSPFARKIFSPLDEPILEHQFSDGKMIEPVVYAPVIPMVLVNGADGIGTGWSTSIPNFHPIDIVKNLKRRMGRLEGEGSEEQPFEPMMPWFRGWKGTPEAAGPDRFKFNGLAEANENNPKEVIITELPVRMWTDDFKARLEDIISGAKGPSWIKDYKEFNDHHHVHFEVMLDEKSVKAVMDEGILERFKLNKQVATSNMVAFNHRGQIHKYENTEEIMEEFYHYRLEMYETRRKYWLDIYHSDFRKIKNQARFIQEIISGKLIVYKKKKDALVQELRDRNYEPFPKNDKKSSEDGDNPIENQDDNDIGSASDYDYLLSMPIWSLTQERLERLLEQISRKKEEYDTLEAKTAKGLWVIDLDALCAEWQTQLQLDAEIRTDIRRKGRRASKKIASSRGRKAVKAGDDDYNPTTKGSRAKKTAASAAKATSEKAHMRFQEMFNNGQDKKGKVKKEEDDDGAEISDLSDGDFAALTRSKPAASKTSSSKASTSKPSTTSKKGAKAAVKEESADDFDDDDDDVVPVKTTLPRRAAAVKASKKTFSFSDDESDDDNLLGDVGDMVKGIGSKESESEDKSRLSKFSMSSTSGSAAAAAAAAGALPKSRAKASGNSKSSAFDFDDSNDETNYEMLAKSSPIKPKKSEGVKDESDDEDLFDLSDVKPTRRAGASSTSGVLANLGAKKVRKPASASAATKAKEKAQVAKRPGSSTVLSPAAKAYAAKKASSKFAISDDDSDEAKQEEEEEEGEEEGEEEEETFDSSVPAAKPVGKASASRTSSAKPAKAPAKSKAAPPSTKAKRGRASVLSDDDDGDEINMADEFDDSLPVRSSSRPSRKASTARKPARYIELSEDDDDDDDFEMGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA77</accession>
    <name>A0ABR3ZA77_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PKH1_2</name>
        <name evidence="3" type="ORF">Cpir12675_002289</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000043">
        <property type="protein sequence ID" value="KAL1897561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10568">
        <property type="entry name" value="SWIB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.245.10">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019835">
        <property type="entry name" value="SWIB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036885">
        <property type="entry name" value="SWIB_MDM2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003121">
        <property type="entry name" value="SWIB_MDM2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13844">
        <property type="entry name" value="SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02201">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00151">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47592">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51925">
        <property type="entry name" value="SWIB_MDM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DM2" evidence="2">
        <location>
            <begin position="266"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="492" mass="55456" checksum="7B5DF2C68D081D6B" modified="2025-10-08" version="1">MHGGQFRQFNAGTGGRGGRRGQNAANNAAAQAQLAQQQAAAAAAAAAQQAQAQAQAQAEMAKRRSQKPTDKNMPEGIENCIPDGELVEHYNKLRNYERRLDATITRKRLDALDSVNRYPKYWRSLRIWISNTVEDQPWQQTSLNVDSFDFSSTVDSTYKVKIQARLLADDMGPESKNGSDDDMDSDVQNKGDEAMEYHLPHFFRAMNVEFPQSYVPEQAVEWKRPDLPPNTASYAPLPEALCFDELSFRRNGDDNMNITINLTRHEEPERYLLSPDLAEIVDMTEGTRQEVAQALYEYISYFKLQEDEERRNFRCDDLLRKIVNSDVGHIPMLGDYITPQLKPLPPISLPYTIRVDKAFHSDPTPSVYDVRVLVEPPVKTQIVKFISHPSYATMLREVSGLDEQLASLIQAISVSKAKRTFFMSLANDPVNFLRKWISSQQRDLEVISGQTIRGSSGSGADTWRKGGPGSVWTTSAAQESVSILLSKQPRHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA84</accession>
    <name>A0ABR3ZA84_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NADH-ubiquinone oxidoreductase 21.3 kDa subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002838</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000059">
        <property type="protein sequence ID" value="KAL1896434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22849">
        <property type="entry name" value="NuzM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016813">
        <property type="entry name" value="NADH_Ub_cplx-1_21kDa"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37325">
        <property type="entry name" value="OXIDOREDUCTASE 21 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G05910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37325:SF1">
        <property type="entry name" value="OXIDOREDUCTASE 21 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G05910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF022976">
        <property type="entry name" value="NADH_Oxi_21kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1896434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="187" mass="20042" checksum="F2838DE8518D98A1" modified="2025-10-08" version="1">MASKAVAKTVAGGVVEISKKYTVQSSGLWEILRRFLAIDPNRSNGVPLNPLNRLPAPGSIDPQAYRDPVTFPAGDIAGNPYWKRDHRRNYPRSSVVTQPQVVSLLTVGSAAAPKAELLGEAGEKALVAAVQESQGGIAAFLEKNADVAAKDVFVNGLPPTPSGLNLKQDGQWDTYKFKIGENSYPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAD5</accession>
    <name>A0ABR3ZAD5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glutamine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">GLN4</name>
        <name evidence="14" type="ORF">Cpir12675_002388</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>tRNA(Gln) + L-glutamine + ATP = L-glutaminyl-tRNA(Gln) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:20121"/>
            <dbReference type="Rhea" id="RHEA-COMP:9662"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.18" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000046">
        <property type="protein sequence ID" value="KAL1897284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004819">
        <property type="term" value="F:glutamine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="entry name" value="Ribosomal Protein L25, Chain P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004514">
        <property type="entry name" value="Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050132">
        <property type="entry name" value="Gln/Glu-tRNA_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020059">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_codon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_bL25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_bL25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049437">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00440">
        <property type="entry name" value="glnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097:SF4">
        <property type="entry name" value="GLUTAMINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097">
        <property type="entry name" value="GLUTAMINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03950">
        <property type="entry name" value="tRNA-synt_1c_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20974">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="Ribosomal protein L25-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic" evidence="11">
        <location>
            <begin position="116"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding" evidence="12">
        <location>
            <begin position="431"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA synthetases class I (E and Q) anti-codon binding" evidence="13">
        <location>
            <begin position="542"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="35"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="601"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF20974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1897284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="661" mass="73972" checksum="F441A2A3A715BB92" modified="2025-10-08" version="1">MSESPAPPPATATEATSTASLVAEVTASVAKLVLDEETGEMVSKNELKKRMQKRSKKAAAAQHKAKAAAEKKPEGAKANKPAKKEATEAESPLDPDAMFKQGFLADVFNIRPMKPVITRFPPEPNGYLHLGHAKAIAINFGFARYHGGKTILRFDDTNPDAEEEKYFTAIKEMIAWLGFQPAAITHSSDNFQKLYDLAEKLIDLGKAYVCHCDAAAIKIQRGGENGSIPRTRCEHAETDKAINLTKFRDMRDGKYAPQTAVLRMKQDIVNNNPQMWDLAAYRIPKNQTHHVRTGEKWKIYPTYDFTHGLCDSFENITHSLCTTEFVLSRESYEWLNTSLGVYEPMQREYGRLNVAGTVMSKRALRTLVEQGYVRDWDDPRLYTLIAIRRRGIPPGAILSFINELGVTTAKSVIQIARFEQAVRKYLETTVPRLMLVLDPVPLVIEDIGDLENTELELPFSPKDPKMGSHKVTLSKTLYIDRSDFREEDSKGYFRLAPNKSVGLLQLPFPIKAVSYSKDETTGKVTEIRAVFDRDGKKPKTYIQWVGAGARPAEVRIYKQLFKSDDPMTLKEGYLSDINPDSETIWPAALVESGIADIKQRAPWPATEGEQKKTSAEGVTASAPETVRFQGMRVAYFAMDPDSTEEKLVLNQIVSLKEDSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB55</accession>
    <name>A0ABR3ZB55_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Cpir12675_002318</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000044">
        <property type="protein sequence ID" value="KAL1897530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF143">
        <property type="entry name" value="EXTRACELLULAR MEMBRANE PROTEIN CFEM DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00747">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="14" id="KW-0349">Heme</keyword>
    <keyword evidence="14" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="10 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="8 17" id="KW-0732">Signal</keyword>
    <keyword evidence="7 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047054642" description="CFEM domain-containing protein" evidence="17">
        <location>
            <begin position="22"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="212"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="333"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="18">
        <location>
            <begin position="4"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="388"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="466"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="32"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="36"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="46"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="55"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1897530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="500" mass="54367" checksum="DB0165914FA80640" modified="2025-10-08" version="1">MRLFASLVSALVMAGAAATAATTNSLASLPSCSLTCMATLVSNSSCALDDTTCVCTNKLLVASIEKCVAASCTPKEMLTTINVTSTNCGVVPRDKRRTYDTVSITLGIITGIVVAVRISFKLFVIHDQLNLSDIFILATMGSGIPSTVMNTTGLTKHGLARDIWTVPFDDITLFGRYYYVMEVLYFAHVTLLKLSILFFYLRIFPAPGVRRLLWATVAVVAAFGLAFVIAAIFQCSPISYFWTKWSGETTGSCVSINHLAWANAAGSILLDLCMLAIPLSQLRHLKLHWKKKLGVGLMFCTGTFVTVMSIVRLHSLIMFANSHNTTWDQWEAALWSTIEINIGIICACMPSIRVVLVRLFPRVFDSTFHDHGKGSYYASDQYKRSMPQDNAVSGGLNGNDTLNSPHDNGDSGGISTPTGSHHRAVECDHNVNRGAIDPSGILCSRTYTVKYGADLDETSLVQMADLDRESAKSSSSISDSYERKVPMPSVSRMRVEGAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBV9</accession>
    <name>A0ABR3ZBV9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Molybdenum cofactor sulfurase</fullName>
            <shortName evidence="4">MCS</shortName>
            <shortName evidence="4">MOS</shortName>
            <shortName evidence="4">MoCo sulfurase</shortName>
            <ecNumber evidence="4">2.8.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Molybdenum cofactor sulfurtransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hxB</name>
        <name evidence="7" type="ORF">Cpir12675_002062</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O</text>
            <dbReference type="Rhea" id="RHEA:42636"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:82685"/>
            <dbReference type="EC" id="2.8.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.9" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000036">
        <property type="protein sequence ID" value="KAL1898113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03050">
        <property type="entry name" value="MOCOS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028886">
        <property type="entry name" value="MoCo_sulfurase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005303">
        <property type="entry name" value="MOCOS_middle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237:SF80">
        <property type="entry name" value="MOLYBDENUM COFACTOR SULFURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SULFURASE MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03473">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03476">
        <property type="entry name" value="MOSC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141673">
        <property type="entry name" value="MOSC N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="2 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MOSC" evidence="6">
        <location>
            <begin position="667"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="648"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="648"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="390"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="852" mass="93897" checksum="854EF81A64B6CE2B" modified="2025-10-08" version="1">MATAHFDLLEYNLRVQENRIIEYPSIQDAVYLDHAGTTLYSKSLLDDFSRDMASNLFGNPHSSSLPSQLSTSRIQDTRLRLLAFFGANPHEYDLVFTANTTGAVKLVCDAFRCAPGGFHYVHHEACHTSLVGVREEAEESHCVDDHGMQQWTRRDPYKTQSPLTLVAYTAQSHVTGERYPASWASDVRINDQDDDVHGSVYSLLDLASYAATSSVDLTDVSLAPDFAVVSLYKIFGFPDLGALIVRRQAAPIFNSRRYFGGGTVDTVVCGSEQWHAPKDMFLHERLEDGTLPFHSIIALDAALESHARLYSSMFAVSSHVTRLRKIMLKGLASLKHYNGTPVCVLYSRPDSSSGPVALNIRDSQGAWISLTEFDKLANINEIFVRTGGLCGPGSIASLLGLKPWEIKKNFSAGFRCGSSGNDIISGKPTGVIRASLGAMSTEKDIHRFVEFIREFYCQATPPSLLEFPTNPVSQSQVSGLIVKALTVYPIKSCGGYQVPKGIPWEMKPEGLAWDREWCLVHRGSGQALSQKRYPRMALLRPYIDFEAGVLRIQYLGSSNEETATRQITVPLSMNPTLFRPSATFNDKKPTREITSRVCGDNIITSIYTAPEINDFFTDVLGVPCALARFPPGGQDQAMRFSKLRNGQPLQINDRSSRSSGNISPVVSWLESRPPSPPDSDSEMQGGKLLLANESPILLIHEASVQAISKVIEDSGGRKIPAASFRGNIVVGSGEQLDAPVMQAYSEEQWLSLRIQRQEFQVLGSCQRCQMVCINQQTGYKDTEPYTTLAKTRRVDGKVYFGMHIAHVIPQLNNLGGTSIDRQLPFIQVGDAVLVTVRGSAQLHGLESSNNKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC86</accession>
    <name>A0ABR3ZC86_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002003</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000035">
        <property type="protein sequence ID" value="KAL1898296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="100"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="333" mass="36611" checksum="104028C4B0A8D25D" modified="2025-10-08" version="1">MPNSSVNAPWKLDPEFSKATSAIYTARSVTPKTPASAINLRRQMFNATTKMLRYTRTTKLDPRVQVAQYEFPSSLDGTNIKIFHYFRSDIHKGGPLTAALLHCHGGGFMSGSVDILDEGVRLHVGVTGIPWFSVEFRLAPEHKYPTQIQDCFDGLKWLHAKTAEFNVDRRRIGVVGESSGGGLALGVAMLARDQALSPPLAKQILVYPMVDDRILTADPKVEPIASMTIEDIICGWTCMLDVPPGSDDVPIYAAPGRATSEDLVNLPPAYIEVGVIDTFRDSIIELVQKLLKAGVMTDFHLVNGQVHAAEFLAPETAISKRYLELRQQAMASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCQ3</accession>
    <name>A0ABR3ZCQ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">UTP--glucose-1-phosphate uridylyltransferase</fullName>
            <ecNumber evidence="3 6">2.7.7.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">UGP1</name>
        <name evidence="7" type="ORF">Cpir12675_002050</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a central role as a glucosyl donor in cellular metabolic pathways.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>alpha-D-glucose 1-phosphate + UTP + H(+) = UDP-alpha-D-glucose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19889"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.7.7.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the UDPGP type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.9" evidence="3 6"/>
    <dbReference type="EMBL" id="JAWDJO010000036">
        <property type="protein sequence ID" value="KAL1898102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003983">
        <property type="term" value="F:UTP:glucose-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00897">
        <property type="entry name" value="UGPase_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002618">
        <property type="entry name" value="UDPGP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016267">
        <property type="entry name" value="UDPGP_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43511">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01704">
        <property type="entry name" value="UDPGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000806">
        <property type="entry name" value="UDPGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="500" mass="55990" checksum="BA5992A977B4D68E" modified="2025-10-08" version="1">MQCNTILTDRPKQAFENTSTNVAAAQMRNSLTNLAESVEDPEQKAMFETEMDNFFALFRRYLNDKAKGNAVDWDRIRPPAQGQVVDYDDLATSEGTQFLSKLAVLKLNGGLGTSMGCVGPKSVIEVRDGMSFLDLSVRQIEYLNKTYNVNVPLVLMNSFNTDEDTASIIKKYDGHNLEILTFNQSRYPRILKDSLLPVPKKYDSSINEWYPPGHGDVFESLYNSKILDQLMERGIEILFLSNADNLGAVVDLRILQHMVETDSEYIMELTNKTKADVKGGTIIDYEGSVRLLEIAQVPKEHVNEFKSIKKFKYFNTNNIWLNLKAIKRVVENDELEMEIIPNGKTIPGDSKGESDISVLQLETAVGAAIRHFRNAHGVNVPRRRFLPVKTCSDLMLVKSDLYTVKHGQLQMSPNRFGDAPLIKLGGDFKKVSDFQKRIPSIPKLIELDHLTITGAVNLNRGVTLKGTVIIVATEGSTIDIPPGSILENVVVQGSLRLLEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCR8</accession>
    <name>A0ABR3ZCR8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002066</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000036">
        <property type="protein sequence ID" value="KAL1898117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058155">
        <property type="entry name" value="Skg3/CAF120-like_PH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25381">
        <property type="entry name" value="PH_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="24"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="604"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="404"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="433"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="458"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="490"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="554"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="642"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="656"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="736"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="800"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="818"/>
            <end position="841"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="861" mass="93576" checksum="F71365850F95BBCE" modified="2025-10-08" version="1">MEIDEDTIPELQHVFNLLNSHGNKLYQEGYFLKLDDQDSNGKPNADRTWTECFAQLVGTVLSLWDAAELDAAGEEGEVLPKFINVTDASIKMIDSLPTRGDEQPLQNILSVSTAGRNRYLLHFNSHDALVQWASAIRLAIFEHNSLQEAYTGGLIAGKARTLNNVNLILDRWRVPSEAWVRVRFGAGTPWRRCWCVVTPPDEKEYLKLQKTVKKKSAYDRSMPILKGDIKFYDVRRDTPKKQKKVDPIASISDAYAAYALYPQAKSLVDNSTLIKIEGHITIHSSPPSSTEGFVFVMPEVPPAVGGFEMLLRFLFPTWDTFALYGRPSRLAASNLDSRSLMFAMPKSKRYGYLDLEDVSEIITKQPASSGWTEAEWRKKLKECTGNRLNEMNENGGVPPRHSRSSSNQSNLSGRMSNPPTAGPPPSRTRVGFSDSPPSSSPSNGPPPSQRSMPPGPPQAQYQGQQPMNPQQLPPLQMQQPIPPNGLVPAGMLMGNGMSSNGMVPQNGRSPMDQQYQSFSRPNNLPTPPPAELSAPRTPNGGPSSMFAPGAGNSHDPSASRGTPNQYDQAHVDGYNDYAPSAIYDAMGSDQSPVSIAELESMRLSTPEPVVRPPEFNNRAPPNGQNGAPRSAYHTEDMRRATQRFSDGTMDQINMSNRQNQGGPQNRGPNGMAPQNRGPSNGPPNGMGGSQNRGPPPNGMGGSQNRGPPPNRGPPNGMHPQNRGPPPNGMGGGPQNRGPPPNGMPPQMRGPPPNGMPLQNRPPLNHGPNSYGPGPGSRQGSRPPPNHQQPRGGSPYGGGDPRSQGPPQQRGGPPPSQPPYHQQQPQKYPPSHNQQGPPQQWRGPPPSNHHSGTVPVSTKIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD88</accession>
    <name>A0ABR3ZD88_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mitochondrial heat shock protein Hsp10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hsp10</name>
        <name evidence="4" type="ORF">Cpir12675_001988</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GroES chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000035">
        <property type="protein sequence ID" value="KAL1898282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="entry name" value="GroES chaperonin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00580">
        <property type="entry name" value="CH10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018369">
        <property type="entry name" value="Chaprnonin_Cpn10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="10 KDA HEAT SHOCK PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772:SF0">
        <property type="entry name" value="10 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00681">
        <property type="entry name" value="CHAPERONINS_CPN10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="105" mass="11362" checksum="FD549C4C02B1F26F" modified="2025-10-08" version="1">MLATSLRSIRSLAPLLDRVLIQRVKAEAKTASGIFLPESSVEKLNEAKVLAVGPGSLDKEGKRMPMGVSVGDRVLIPQFGGSPVKVGEEEFQLFRDSEILAKINE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDD3</accession>
    <name>A0ABR3ZDD3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WLM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002039</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000036">
        <property type="protein sequence ID" value="KAL1898091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.10">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053136">
        <property type="entry name" value="UTP_pyrophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013536">
        <property type="entry name" value="WLM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30399">
        <property type="entry name" value="UNCHARACTERIZED PROTEIN YGJP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30399:SF1">
        <property type="entry name" value="UTP PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08325">
        <property type="entry name" value="WLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51397">
        <property type="entry name" value="WLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WLM" evidence="2">
        <location>
            <begin position="10"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="400"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="496" mass="54131" checksum="776DF4BA65DDE237" modified="2025-10-08" version="1">MSSGFTRLNVKKSPPNANITFIKPLAGPNEAIAQDFLERIAAQCYPVMKTNHIRVRSLEEYEPNREFVGRNFNAGEVVQLVLRSPSSGRWLPFEYVQMVMMHELAHCKQMNHSRAFWTVRNHYAAHMERLWATGYTGEGIWGVGRALASGITEQPTILAGEHVPEHLCGGTYRTNTSGLGRGQARKRRAPKLSYKEQKERRVLRKFGANGVAVGSDDAIKIGLEKGVGGGTARQKAPARPRVAGSMRGRELRAAAALARFDQCQGQIQKKEEHAAEVKHEVIELSDSDDGSDGSDVVVVPDALDIDGKRMTDKDGVGLVKIYDDDEGSSAADDIKVLASDELQELSKRFWGMPGSCHASEPVKLEQQDNNEAGKLPQRPRAPATNLPKPESGAPKLQLSKVPVRAKPVAVPRLRAVSKPPSLRRPPLSSSQTKKASSRVTELSFTRTLGSSTLESASTRATLSSGGHVLGHSKARDPRQRSVADMFRTGLDNSRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDI1</accession>
    <name>A0ABR3ZDI1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_002287</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000043">
        <property type="protein sequence ID" value="KAL1897559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14705">
        <property type="entry name" value="bZIP_Zip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13044">
        <property type="entry name" value="ACTIVATING TRANSCRIPTION FACTOR ATF 4/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13044:SF14">
        <property type="entry name" value="CRYPTOCEPHAL, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="8">
        <location>
            <begin position="176"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="130"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="197"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="139"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1897559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="276" mass="30533" checksum="EECC2E08DE0C7464" modified="2025-10-08" version="1">MASYSNGRRAPNATRYLSNLNMLEPAAPAADESYNLESDLALFTNAQFFDFDSGQNTDFQAPPPSTEIKREPVSATTASTTEIDDISFIPSDFNFDFSNTYTTPTISGFPTDGLGLPQMQPAAAIYSSSVQQAQPQQPNTFDQPVTGTQTVENHSSEPHPPGALNFEERSRLAAEEDKRRRNTAASARFRIKKKQREQALEKSAKEMAQKVSELENHISQLETENKWLRNILLEKNENSEHIATILEKGFPGKDEVDRVAKELATKTSSTPTPSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE08</accession>
    <name>A0ABR3ZE08_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RCC1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_002254</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000041">
        <property type="protein sequence ID" value="KAL1897754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051553">
        <property type="entry name" value="Ran_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982:SF1">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00625">
        <property type="entry name" value="RCC1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="187"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="RCC1-like" evidence="5">
        <location>
            <begin position="188"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="248"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="328"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="381"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="439"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="496"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="561"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="262"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="85"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="138"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="265"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="275"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1897754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="626" mass="66435" checksum="58F960D2D5D0DF4C" modified="2025-10-08" version="1">MASSRTAAAAKAAKATKTEELKTSKKVAPKTAAKKEKVAPPAEKPAASRKRKADDSEVDVPKAKKSKAVSEKPVPTATKSKPAAKKTDAKKPATVKKAEPKKTEPKKAEPKKTEPKKAAAPKKSTTKKAAVSKKVEVSEDEDVEMEDAPAPKAPAARPKKVPVPKLPPPPKVRTAGPTINDMPSQRLEVFVFGEGSSGELGMGSKRRDGKKPVDVKRPRYNDLLSAKDTGVVQIACGGMHVAALTADGKMLTWGVNDDGALGRNTEWEGGLRDMDNEDDSDSDDEDDTGLNPMESTPTAVSTDVFIQGTQVSQVAACDSATFALTRDGRVYGWGTFRASDGILGFSETTKVQRTPIEISGLKKITLLAAGSNHMLAVDTKGEITAWGSGEQAQLGRRIGERYKMKALQPQHVGIPKSKTNPIVKLACGSYHSFALNKEGGVYGWGLNNFGQVGVEGGAGEGDAIINSPSVIKSLSEYKIKDIAGGEHHSLACTHDGKLLVWGRIDGHQVGLPKEAYTEDNTVFDDKKRPRLLFKPTIVEGIPPIESVAAGTDTSFAVTTDGKVYTWGFSANYQTGLGTTDDIEEPAIIENSAIKDKRVIVAGAGGQYSLLCALPDNETLTNGTAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE23</accession>
    <name>A0ABR3ZE23_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Profilin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PFY1</name>
        <name evidence="7" type="ORF">Cpir12675_001887</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the profilin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000032">
        <property type="protein sequence ID" value="KAL1898422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00148">
        <property type="entry name" value="PROF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048278">
        <property type="entry name" value="PFN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005455">
        <property type="entry name" value="PFN_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036140">
        <property type="entry name" value="PFN_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11604">
        <property type="entry name" value="PROFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11604:SF0">
        <property type="entry name" value="PROFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00235">
        <property type="entry name" value="Profilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00392">
        <property type="entry name" value="PROFILIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01640">
        <property type="entry name" value="PROFILINPLNT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00392">
        <property type="entry name" value="PROF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55770">
        <property type="entry name" value="Profilin (actin-binding protein)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="82" mass="8745" checksum="E9A6F7403481A7A8" modified="2025-10-08" version="1">MGASKQTVVTNAQENGIHLNNERFVVFRAEGRSLYGRKGREGICAVQTSQAIIVGHYGEGQQAGNCSVAVEGLADYLIGQGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEB9</accession>
    <name>A0ABR3ZEB9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcription factor IIF subunit tfg1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TFG1</name>
        <name evidence="8" type="ORF">Cpir12675_001658</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIF alpha subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000027">
        <property type="protein sequence ID" value="KAL1898998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008851">
        <property type="entry name" value="TFIIF-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011039">
        <property type="entry name" value="TFIIF_interaction"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13011:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13011">
        <property type="entry name" value="TFIIF-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50916">
        <property type="entry name" value="Rap30/74 interaction domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="125"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="323"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="75"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="165"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="207"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="323"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="355"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="460"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="541"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1898998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="669" mass="75011" checksum="331619FFAC8EEBF9" modified="2025-10-08" version="1">MSAPPPSGPPQPMSTPTPNGALNGSQGLPARRPPPQGLRPPRRRPADPMVARKRPNAAKQIGFRKMADSTSMDRFPTKSLEDLQRRRQQYDGWSEPPPNVSYADYPVVTTKRELREHMRIHAMRFIKSKGGDDSTVIDPTNQNEFTRPVTLHRRDPRQPPPGRAPPKEPTPEPVTVDEKESERLAQLKADKEAQRAIDQAKIAPGIKEQKQSKQKPKEEKINLNRMPTTAKGKKQSDIRYEEALPWHLEDADGKNVWVGSYESALSESYVALLIDGNKFRMIPIEKWYKFTAKPPFVPISADQAEDMLRKQIPVTRWLMKKEEEKAEGQKRMQEFRAASGPAKRRRPDQESRDYDEVDMDPGDEFQDDDETGGVLDFDDEDAKISSERIRKNQLGANLFGDGDEKDVDEKESVQMRDERIKREQSRKLKKKFLKRVNENAIESDDSDSDPFLAQASSANEDSDEEEEEKKEEEKQKDKPEDEGEEDKTKGSETSNAKKAVPDPLKKKSLKRAGSPGASESSGNESSRKKSKIKKIGVAGQSRASTPLASTQRRKVGGAANLSDDGEATAGEMSDSHPRKKIRIIGNKPVASGSRAGSPVPPIVSIGPIQPQEIIAALPELPDGITILNLFKSFDDRVGDRPGLMSKSDWLKLVRENSQYGQDKLLRRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF35</accession>
    <name>A0ABR3ZF35_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001506</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000024">
        <property type="protein sequence ID" value="KAL1899313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="270" mass="30983" checksum="F22F7F37EA654A8B" modified="2025-10-08" version="1">MHKLTVVDLGAIAAMCKGNFVFWFQRSQDGFTGLLEVVQNNDFDPTIAIERKSVKRKLAFATRTKNIKPGILRCHLQWRATFAQPITSYAINSSQMFETTILHRIVAASTTLPKAEHDTALTKRREARKKWKKSNKESYDRQHTRFLARESDYKPAKDLGRYGDYDCVDTGLSTVENKDGTVTTTVKKMINQYSPLYLWWKTRKLRAFFPLSYKEVDMLLQLCDIKSIHPSLESKGSTCDANELRKRARRVRGGKKADTEKPLTTRIGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF78</accession>
    <name>A0ABR3ZF78_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Mitochondrial carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Cpir12675_001724</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000029">
        <property type="protein sequence ID" value="KAL1898721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45667">
        <property type="entry name" value="S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="40"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="135"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="239"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="275"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="22"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="275"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1898721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="379" mass="41949" checksum="0DB07B735359376F" modified="2025-10-08" version="1">MFSTDSKPKPQISMAPSSTTHNAKDQRQKQGSHGVDDDRPPYLHTMLAGGLGGSTGDLLMHSLDTVKTRQQGDPNFPPKYKSIGSSYYTIWKQEGIRRGLYGGWQAAMMGSFPSTVLFFGSYEYSKRLLIDWGVQQHVSYLTAGFIGDFAASIVYVPSEVLKTRLQLQGRYNNPYFVSGHNYRGTIDAARTIVRQEGFSALFHGFRATLTRDLPFSALQFMFWEQFSAWAKQYKQSRDIGAPLEMMTGASAGALAGFLTTPLDVVKTRLQTQVTPTTTSAAAPISTPTTAGRSPRHKRGIAMSSPSAHTPKPSALNLDTSSAIRGLQLIYKVEGIAGLFRGVGPRTMWTFVQSGTMLFLYQRLLRQLEVYMPLKEEKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFB8</accession>
    <name>A0ABR3ZFB8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001524</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000024">
        <property type="protein sequence ID" value="KAL1899326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="153"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="256" mass="27785" checksum="86B93B37E9224DFF" modified="2025-10-08" version="1">MRVQRYATPRKLQILINSETFGKDSQTSAGAMKNYQQILRLMKKAAEHTKYTGKKSVMIYSSVGGKDPSSSANGLPIFTGTSSLEQKEYCWSLRTCEDYEGGYTADDEYEESIHGEVASLSDVMIDPGPRRQVTVVEASIITAVTQRAVIDSVGSANSGDSSDSLSSLDATTTTTVSSTQKSNLTTRAKAIVHRVKGSMQDFGHRLKENSKKSSIPMGPAHPDPLDDIDNVGDLIANTAINPSGREASRLLLFNHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFT4</accession>
    <name>A0ABR3ZFT4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Extracellular serine-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001593</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000026">
        <property type="protein sequence ID" value="KAL1899037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052953">
        <property type="entry name" value="Ser-rich/MCO-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883:SF20">
        <property type="entry name" value="PHYTOCYANIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883">
        <property type="entry name" value="SERINE-RICH PROTEIN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047168828" description="Extracellular serine-rich protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="167" mass="17981" checksum="F84596542099F78E" modified="2025-10-08" version="1">MQFALTTLLAATAVLAAPSKTTGDVPSLVRREASTHTVVVSGEKFLPRRTKADVGDSVLFVFLEGKHAVQESSYESPCAYLEGGFSSGTLDIKNSAEGESFYVDIIDTNPIWFYNGVEKRCHESGIVGAINSPENDEKSIDMLEIAAKRKSVTLSTTFSVGVTWVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGA9</accession>
    <name>A0ABR3ZGA9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tr-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001301</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000019">
        <property type="protein sequence ID" value="KAL1899716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF30">
        <property type="entry name" value="TR-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="2">
        <location>
            <begin position="281"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="600"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="847" mass="91575" checksum="3BAFE20DF8E8711F" modified="2025-10-08" version="1">MASIFNCETDQTRVSSPWLVSLGSSPLRSRSQPPIITPLTDAANEDCPNGVQVGLLSDYRIIKLEAEPQMGPTEYKLHLLLRPRRQFRSMSTYQSISKYAKLKDGSFTPPLASSNQSRHDRLQHLTTQLLWRMQQSSPQHTGTSLDTVVPQLPSDGTDLDTIVVPAKLPPGLEESRGALYEIGVSDDGTLVGLTNDEMDESIKTLRVMSASLGCKVEILRMIIVGEGEWDDLTQPNLVVRGSLWVAEAFVTPGLKNNMTTFLSWGPDPDANEPSSTDQLRVTLTGPTASGKSTLLGTLTTGTLDNGRGMSRQSLLKHRHEVESGMTSSVAQELIGYKNGTIINYQSHYNDMPWGEIHELSREGRLVFVSDSAGHPRYRRTTLRGIIGWTPHWMVLCVAANDGELSSVFSSTGSQGEPDLALAHLVLCLELRSPLAVVITKLDKASKGSLQHTLGKLLTAIKTAGRVPKIIQPDQVCHTTLTHIPDSDNAKVKSVVDSITASNDFTRVIPILLTSAVKGQGIGMTHSLLKNLPIPAPPKANELSPEQPASIFHIDDVFNVPVLRNARPDSMCDQDTDAGIVVSGYLRFGVLRVGDEIVIGPFPSEDDPKKTQSPRDQPSGGGMGLSVSHRASSELAKLALKNTVLASQVGIKWHTARIASIRNLRLPVSKLQADQVGTIGLIVLPSAGSQVGADSHQEAKIRGLSIRRGMVIAVLSQHMINSGMSLQAASFITIQVIYRNAERLQVGTLVNVYAACVRSAARIRSMSKVRVCIDHDVTTGNGGDEEGLFGMETGNGKDASQDVAEVVIDLISSREWIELGSQVMLLEGGSKDKTGLEGITGRVVRVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGH1</accession>
    <name>A0ABR3ZGH1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Arginase</fullName>
            <ecNumber evidence="2 10">3.5.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CAR1</name>
        <name evidence="11" type="ORF">Cpir12675_001490</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-arginine + H2O = urea + L-ornithine</text>
            <dbReference type="Rhea" id="RHEA:20569"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="EC" id="3.5.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="10">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the arginase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.3.1" evidence="2 10"/>
    <dbReference type="EMBL" id="JAWDJO010000024">
        <property type="protein sequence ID" value="KAL1899297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004053">
        <property type="term" value="F:arginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd09989">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.10">
        <property type="entry name" value="Ureohydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014033">
        <property type="entry name" value="Arginase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020855">
        <property type="entry name" value="Ureohydrolase_Mn_BS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01229">
        <property type="entry name" value="rocF_arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43782">
        <property type="entry name" value="ARGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43782:SF3">
        <property type="entry name" value="ARGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00116">
        <property type="entry name" value="ARGINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01053">
        <property type="entry name" value="ARGINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0056">Arginine metabolism</keyword>
    <keyword evidence="6 9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 10" id="KW-0464">Manganese</keyword>
    <keyword evidence="5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1899297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="334" mass="35943" checksum="41EA54593A943C22" modified="2025-10-08" version="1">MASSSNQIVSSKTDNKFLSCPEDVAVVAMGFAGGQGKSGVDTGPAALFEAGLLDELSLDLGYNLHGDRDARIYIQDDAEADEPHRNMKKPRYVSKTTKQISDQVYRHAKEGRMLLTVGGDHSVAIGTISGTAKAIRERFNGRRELAVVWVDAHADINTPETSDSGNIHGMPMAFLTGIAKSDNPDIFGWVGPEHMVSPTKLVYIGLRDVDAGEKKILAENGIKAFSMYHVDKYGIGKVVEMALAHIGADTPIHLSFDIDGLDPIWAPATGTPVRGGLTLREGNYICEALHQTNCLVAMDLVEVNPDLKKSEDEGSNTLRAAKSLIRSALGDSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGP9</accession>
    <name>A0ABR3ZGP9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2470 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001822</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000030">
        <property type="protein sequence ID" value="KAL1898714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.10">
        <property type="entry name" value="PNP-oxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019595">
        <property type="entry name" value="DUF2470"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037119">
        <property type="entry name" value="Haem_oxidase_HugZ-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37783">
        <property type="entry name" value="MEMBRANE PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G04315)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37783:SF1">
        <property type="entry name" value="MEMBRANE PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G04315)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10615">
        <property type="entry name" value="DUF2470"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2470" evidence="2">
        <location>
            <begin position="10"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="254" mass="27974" checksum="7FD19C938BDDE085" modified="2025-10-08" version="1">MATPTDSDIKTRIITHMNHDHARELTHYLRAFSGLSAHAARSEPTLADVSLAQLTLTTATAGGGLETHTIPLSPPLANLGEMRTRLIEMDVTARKQLGGISDISMSGCYKAPRGFDAVVFFLVATYYMQWAALDWVAAAHAAATTGASGGDLGWTTSAGNSVWLFWDAVFGALGAGGWTGYVMVVRAIVIPVLLIHFVEGIWFERSRLDKHDVVRFEASWWLWMMSVFFEGFPAFARFDRVVADKKRVKEAKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH02</accession>
    <name>A0ABR3ZH02_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_001178</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000017">
        <property type="protein sequence ID" value="KAL1899956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF3">
        <property type="entry name" value="HEXOSE TRANSPORTER PROTEIN (AFU_ORTHOLOGUE AFUA_8G04480)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="361"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="396"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="425"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="461"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="48"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="521"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="521"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1899956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="560" mass="60936" checksum="B99BBB71F481EEAB" modified="2025-10-08" version="1">MATKHSKAAPATGSAATKPTQNASADLVSVLPSDKWTSQWHIVRLNLAIGSLVLFSSANGYDGSLMNGIIALPSWNRFMDHPRGSWLGLINAMYSLGCVIAYPVAARVSNRYGRKPGLYVGYTSMAIGTALQTLAQSHAAFIIARLFIGIASGFFLSVPLLIAENAYPTQRSIVSALYNCGWYSGSMVAAWVVFATRLVDSSWAWRTPSLLQMLLPLCTLPGFIAIDESPRWLVAQGRDDEARAILAKNHAGGDLDSPLVAFEMREIQSTIRAETASGGAKWADLWATKGNRHRLWITVTLGIFTQWVGNGVVSYYLSLVLETVGITSVTHQTLISACLQMWNLFWASLAAFNSDRLGRRMLFLASGSIMLVSYSIITGLSGSFASTGNKATGLAVIPFLFIYFFGYDISLTPLLVSYPVEIWPYALRAMGLSVAFVVALLCVFFNTFVNPVALDSMGWKYYIVFVVFLVAMLVTVYFTYPETRGHTLETIAYIFDGDDTAPLNVPTHHGAPVVIGHVDKASGSDTDPASREANDSDYASSSSLAHMLPESSTDRLTRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHG7</accession>
    <name>A0ABR3ZHG7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Altered inheritance of mitochondria protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">AIM6</name>
        <name evidence="5" type="ORF">Cpir12675_001099</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AIM6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000015">
        <property type="protein sequence ID" value="KAL1900096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051236">
        <property type="entry name" value="HAT_RTT109-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31571">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31571:SF1">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="15"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1900096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="394" mass="44238" checksum="7356BF4D0C494D6B" modified="2025-10-08" version="1">MATQFGLRQRGPPRSSISQLSRANSTSSSTHTITEMARSTSVLSEKHPQNNILPLSRSDTHLDCNDSSQSCSPLLNPEGKSLCHTHRSHPKRPSNLSSLVYFAIVACIILGASRAWFQNHQHHRLVTVGVPLSCHSHNDYWRKRPLFDALEAGCTGVEADVWLRNNELYVVHEAPQTPALPTFTQLYVNPLVNILEQNNNGLAQGNTPVGVFSNFPNQTLILLVDFKEDSQAVFDTVSAQLQPLRERGWLTYFKDGSLTEGPITVVVTGEARLSSITANTTYRDIFLDAPTLALNDDTTHAYNWTNSYYSSVKFGRAFGHYTGYMGRPRIDDIATYVQQAHERGLKLRFWSQPSWPVLVRERLWGDLLDAGVDYLNVDDLIGANEWLAKREDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIH3</accession>
    <name>A0ABR3ZIH3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acid phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_001394</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000021">
        <property type="protein sequence ID" value="KAL1899623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050645">
        <property type="entry name" value="Histidine_acid_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567">
        <property type="entry name" value="ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567:SF142">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046972447" description="Acid phosphatase" evidence="3">
        <location>
            <begin position="20"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="430"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1899623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="513" mass="54933" checksum="F0CCC5265BC64DB1" modified="2025-10-08" version="1">MLGALKIAPLLALASSAAAETVYGAAVFSRHGDRTTKHYKNQQLTTVGANQNFVMGSAYRSRYLLSSSESQIANISEDKYVSSQVYANAPDSGILLATANYFLQGLYPPLDTINAAEAGTALANGTKVAAPLAGYQYVTLHAENANSPDTMWIKGDENCPAQAATISAWEASPVFAQRVSDSKDFYESMYPALNEVYDYTDPAQLSYAQAYDIYDLINVARIHNASSPAANVTDEQLFQLRTLADSAEFGANFNATNTDSAIHARTLIAAFVSQLNTTVIGKGKLKLSLFSGSYNTMLAFFGILQLPEVSPEFYGLPDYASTMGFELFTADNTSAFPADPNNDLRVRFLFRNGTEGTLQAFPLFGTGEDSLTWADFKSRMEAVSIPSTKDWCNVCGSTQIFCLGYQQQESVAAAAAAGASGDKDSMSNTVAGVIGAMVTLGVFGLAGLVTFVLYRRKSKVALLPVVAVSAGNGSVHSSVDEKTHVSMESNVQVKVFHSIETNTTEMANGKVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIS3</accession>
    <name>A0ABR3ZIS3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquitin-like modifier HUB1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_001176</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000017">
        <property type="protein sequence ID" value="KAL1899955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039732">
        <property type="entry name" value="Hub1/Ubl5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13042">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="19"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="45"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="98"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00014108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1899955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="224" mass="25540" checksum="731DCEE18ECC0127" modified="2025-10-08" version="1">MADESTTRKRSRSRSPAAPRDRDNTRGRRDGDSHPRKPRSGGFGWKDKSRNSTSYADERGDRRGGLERGYRSRRSPSPRRRRDGDNDRDQFQGSASSGRRERERDSGHSRGSNRDRDRRDRDRDDRPPRRDKSKKSATPAAPTSGEEMIIVHVNDRLGTKAAIPCFASDRVKEFKILVAARIGREPHEILLKRQGERPFKDQLSLEDYGVSNGVQIDLEVDTGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ61</accession>
    <name>A0ABR3ZJ61_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribosomal RNA-processing protein 40</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">RRP40</name>
        <name evidence="13" type="ORF">Cpir12675_000845</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RRP40 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22526">
        <property type="entry name" value="KH-I_Rrp40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05790">
        <property type="entry name" value="S1_Rrp40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026699">
        <property type="entry name" value="Exosome_RNA_bind1/RRP40/RRP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049469">
        <property type="entry name" value="RRP40_KH-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041054">
        <property type="entry name" value="Rrp40_N_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037319">
        <property type="entry name" value="Rrp40_S1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21321:SF1">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21321">
        <property type="entry name" value="PNAS-3 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15985">
        <property type="entry name" value="KH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18311">
        <property type="entry name" value="Rrp40_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21262">
        <property type="entry name" value="RRP40_S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0271">Exosome</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exosome complex exonuclease Rrp40 N-terminal" evidence="12">
        <location>
            <begin position="27"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="11">
        <location>
            <begin position="156"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF15985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF18311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1900711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="244" mass="26003" checksum="624BD2C81D8ECA11" modified="2025-10-08" version="1">MATSSTLVLPGQPIDLESIPRNDKKPLRLGPGLNIEPPSTLIPTVSGILTSDVRRNIVWVEHGSGRYVPAPGDLVIGTVMRNAGDLYLVSLSDYTLPAALHNLSFEGANKKTRPMLSTGSVVYARVSSAHRHMDAELDCVSGTTGKADGLGPLSGGMLFPISLGMARRLLLPKAVQDGKMPILEELGAAGLQFETAVGRNGRLWVTSEKVATTIAVGRAVQDVDEKNLDVKAQKKLARKIMEST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJG5</accession>
    <name>A0ABR3ZJG5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histone deacetylase complex subunit SAP30 Sin3 binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001192</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000017">
        <property type="protein sequence ID" value="KAL1899968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038291">
        <property type="entry name" value="SAP30_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025718">
        <property type="entry name" value="SAP30_Sin3-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13867">
        <property type="entry name" value="SAP30_Sin3_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histone deacetylase complex subunit SAP30 Sin3 binding" evidence="2">
        <location>
            <begin position="106"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="170" mass="19473" checksum="CCA62F9378243023" modified="2025-10-08" version="1">MAPSKPRNHDDSKADGPREKGNSKKRQAKETPVLPPIQSRAASPEHPNASIDWLKFDREALHNYRREHTLDTPPTYLHSSYHFWLSLPGSIGTMSPTMVAARRRNHRLQRQTREKLAATVQRHFDETTINEADAMVHFISTLRQQGTRPQRLILTPTEPLINKGVAKQFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJH7</accession>
    <name>A0ABR3ZJH7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ subfamily C member 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">spf31</name>
        <name evidence="3" type="ORF">Cpir12675_000998</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000014">
        <property type="protein sequence ID" value="KAL1900314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46620">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN SPF31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46620:SF1">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN SPF31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="52"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="227" mass="27001" checksum="DA6FB563695AB7B8" modified="2025-10-08" version="1">MGFKKISSAAQAPEKKESEKDALEALNALDSEAKEFDKDAEIDRILRAFRLDAYAVLDLQPGVAESDIKMAYRKKSLLIHPDKTRNPQAPEAFDRLKKSQVELMDEKHRARLDESIADARRLLIRENKWTVHSEELKTAEFAKMWREKTRFVLIEEEHRRRRQAKVQMEEEGREQKRQEEQLEERKRKRQHEQDWEASRDERISSWRQFQKKKSSGESKKKKMKPIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJK8</accession>
    <name>A0ABR3ZJK8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Adenyl-nucleotide exchange factor sse1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SSE1</name>
        <name evidence="5" type="ORF">Cpir12675_001118</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd24094">
        <property type="entry name" value="ASKHA_NBD_HSP70_ScSse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639:SF4">
        <property type="entry name" value="HSC70CB, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639">
        <property type="entry name" value="HSC70CB, ISOFORM G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="660"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="667"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="680"/>
            <end position="697"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1900013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="697" mass="77634" checksum="599EB84AB547DD0D" modified="2025-10-08" version="1">MSVVGIDFGNLKTVIGVARNRGVDVIANEVSNRSTPSLVGFGPKSRYLGEAAKTQEISNLKNTVGCLKRLIGRSFNDPEIQIEQQYISAPIVDMNGQVGIEVNYRGEKERFTSIQLVAMYLSKIKETATKELKLPVQELVMSVPAWFTDAQRRALVDAAEIAGIKLLRLMNSTTAAALGYGITKLDLPGPEEAPRRVAFVDVGHSDYTCSIVELRKGELFVKSTACDRHFGGRDFDKTLVDHLQKEFLAKYKIDIFTNPRAKSRVLTAAEKVKKILSANQQAPLNIESVMNDVDVSAMITRKEFEDMVKDLLDRVHIPLEQALAEAKLTKDDIDIVEVIGGGLRVPSLKDRIQEFFGKPLSFTSNQDEAVARGCTFSCAVLSPIFRVRDFAVQDIVSYPIEFTWEKAPDIPDEDTSLTVFNQGNVLPSTKILTFYRKQPFDLEARYAAPEQLPGAIKPWIGKFSVKGVKADGKEDFMICKLKARVNIHGILNVESGYYVEDQEVEEEIKDEDPNAMETDAPKKTRLVKKQVRKGELPIVSGTHSLDEATRIAFQEKEAAMAAEDKLVADTEEKKNELETYIYDLRSKLDDQLADLASEEEKDSMREKLTAAEDWLYEDGEDATKSVYIAKFEELRMMAGPVLGRYFDKVEAERQAALERAEAERAAKAASKAAESSETASKTDADMVDAEPKAEDPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKW3</accession>
    <name>A0ABR3ZKW3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Histone-lysine N-methyltransferase ASH1L</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_000808</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006560">
        <property type="entry name" value="AWS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050777">
        <property type="entry name" value="SET2_Histone-Lys_MeTrsfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22884">
        <property type="entry name" value="SET DOMAIN PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17907">
        <property type="entry name" value="AWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00508">
        <property type="entry name" value="PostSET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51215">
        <property type="entry name" value="AWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AWS" evidence="11">
        <location>
            <begin position="664"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="9">
        <location>
            <begin position="722"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="10">
        <location>
            <begin position="846"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="312"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="505"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="938"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1087"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1168"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1228"/>
            <end position="1300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1345"/>
            <end position="1420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="119"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="312"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="344"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="362"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="505"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="524"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="960"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="980"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1002"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1021"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1042"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1106"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1173"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1191"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1230"/>
            <end position="1240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1351"/>
            <end position="1388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1396"/>
            <end position="1420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1900794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1461" mass="157169" checksum="B2ADD7FC7E4F73C3" modified="2025-10-08" version="1">MSSSARRPIPSSENNLVVVPAPASIESPPTSIAGDMHHHQEQEEQQRSHHHMSSIDKTRDLHPSTPPTSLSDLYPDHHHSRPSRYSDINMQIESPVDIPTSLSSSSPRKKRDFAAANHVSTPSATTTAATTTATTPTATSVAAIAVIATITPPSEPVALLDDEPSSFLVTTAHDDDFRGHGVDATMEDSSCDTEMPESPKPNRQSKISAFATAATSNNPLSPAALGISASNAVTTPVSSKLRKDRLARSNPGIERPRRAARASAVYNLCKLSGTDVHGKRAAKGDIVSGRIRRKSAVAKLASQQTAIAASSVQDVADSQQQPPVDTALTPAQKTPASIKAQLPQRESSQGATSTIPRLNSFKKSVSVQQKSTRASSSTSSIYTTAAASTPSSLSAHAVMTRRRRSEPVSALQNKRAVISEPLPRNPTANLVSLAPKTGVLSRELKRLRDTDEFAHIDSKPVLHTVWSNGKIMTLPSRSSGRNAKVAAASASSAVPSYGQISSKAASPADAASLSSCHSSSTTRLRKDATPTDDRSEKERTQDVEQLPPVPKKKPVKHYMEHGLYAGQRFTVNDIMRSLTAEERREVARHDEFVPKSSDRDNKLLPSPIFNGLRLLLKGRDFKLPYDVFNPLPPGQSKPGDWRKMAKNRFIGDSKDYWKNTHGEEWQSKCVCTPDDGCGESCQNRIMLYECDKENCNIGKAHCTNRAFQTLAERKVQGNKYSMGVEVIKTESRGYGVRANRCFEANQIIVEYTGEIITEEECQRRMEENYKDNECFYLMSFDQNMILDATTGSIARFVNHSCKPNCRMVKWVVHGQPRMALFAGDDPIMTGDELTYDYKFDPFSSKNMQKCLCGADNCRGWLTSKEAPQQKEAKNQKAAAAEDTKRAVAAATRKSRKIILGTAASKKPALVRGAAAKNRGSTSAAAAATVMASNARRNRASGFVKSTPVTVSSSAAKRKRSAETDDEPKPARKRTRPPPLTSSSTTRRSGRHSASASGQSGKMPRKVTHRHPSKKRIMSRLQSVQSDSDVSSVVSSGSSGTLKPEKPESSEESRLALVDVEMSDSDSISSLSDVDLSDLDEIAAQFADETPDTRVAESKSTAQYSVVHDKPKDTEKATTVDPYQVDINDSYTVPDTPIQGKTKPSRVTNTKNTAKTATKAIAEVVATTASAAPAKEKARSEKDVGLTASATIRKRAPQRSRIKRLPNGEIAVNKKWKVVARNPKSLAAEAKANEEASKRAAEAASSRVQRKRSLPIGPGAKSRMRWQSAKQDWLSVSEPTIADDGSIDDRHATESDLNGQDWQMGAGVSAKLAVSASLTSPVAPTGVMPSSHPSATFPSVRMAMLNRPPPLLSSDASTPPSPSPLISASAPTPASIFHTVPQRPRQQPRTPFLLQEPGSGAIAASPSPSPAGSVVASPAGASRAALNAPPSVLLHVGARPPPLSQEALMLQACEARKALGSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL17</accession>
    <name>A0ABR3ZL17_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">BAR adaptor protein Hob3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hob3</name>
        <name evidence="5" type="ORF">Cpir12675_000872</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07591">
        <property type="entry name" value="BAR_Rvs161p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046982">
        <property type="entry name" value="BIN3/RVS161-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037429">
        <property type="entry name" value="Rvs161/Hob3_BAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174:SF3">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01251">
        <property type="entry name" value="AMPHIPHYSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00721">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51021">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAR" evidence="4">
        <location>
            <begin position="17"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1900735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="261" mass="29967" checksum="656D5D1ABE733272" modified="2025-10-08" version="1">MSWAGFKKNVNRATTQVMMKTGYVEKTNDRDYEIEERRFRTMETAANRLQKEAKGYLDSLRAMTASQMRIAETIDAFYGDAGAKDGVSRSYKQAVEDLDAETIKALDGPYRTTVLEPITRFCAYFPDVNECIKKRGHKLLDYDALRAKVKKLADKPDKDVTKLPRAEKEMEMAKATYEQLNEQLSTELPQLIDLRVPYLDPSFEALVKIQLRFCAEAYSRMAQVQQYLDPETRDLYASGQLDDRVEQVLQEIRELSISGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL58</accession>
    <name>A0ABR3ZL58_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mitochondrial fission process protein 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Mitochondrial 18 kDa protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_000665</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MTFP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000008">
        <property type="protein sequence ID" value="KAL1901175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019560">
        <property type="entry name" value="Mitochondrial_18_kDa_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11001">
        <property type="entry name" value="MITOCHONDRIAL FISSION PROCESS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11001:SF2">
        <property type="entry name" value="MITOCHONDRIAL FISSION PROCESS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10558">
        <property type="entry name" value="MTP18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1901175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="292" mass="31824" checksum="84647F13A26BD4D9" modified="2025-10-08" version="1">MWWPRKKQDKPHEAAPTAPLDSSPSPENAKRLAHENLPESLQKAVRNTATEAAFDKAVDGYGTDSTESNVRYAAYFSRIKTIVSSAHRYVAYTSDIGESFRPVVNPGIVRAAYGVSWMYLIGDVSFEGYKAYWSNQRTLNPGLKMTPTQQKWTGLPEPAADAATSASSSTTAVSLGKVAPLDDYRTVMVQRAIFQSVASMGLPAFTIHSVVKYSGQAMKNVKNKTIRTWGPIGLGLSVVPFLPVLFDEPVENAVEWAFHKAFLGVGGSSAVEGAPATGREKLLNKKPKEKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLD8</accession>
    <name>A0ABR3ZLD8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Nickel/cobalt efflux system</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_000481</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the NiCoT transporter (TC 2.A.52) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004688">
        <property type="entry name" value="Ni/Co_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011541">
        <property type="entry name" value="Ni/Co_transpt_high_affinity"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31611">
        <property type="entry name" value="HIGH-AFFINITY NICKEL TRANSPORT PROTEIN NIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31611:SF0">
        <property type="entry name" value="HIGH-AFFINITY NICKEL TRANSPORT PROTEIN NIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03824">
        <property type="entry name" value="NicO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0533">Nickel</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="280"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="327"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="368"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="396"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1901250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="406" mass="44038" checksum="4836A07822F4CB7F" modified="2025-10-08" version="1">MGFRIQRSDLKKALPWVRISHTVKGIPVASIRIILCLVLVNLIVWAAVAYPLYTHPKLIGNAALSYTLGLRHALDADHISAIDLTTRRLIASGQRPVTVGTFFSLGHSTIVIITCIVLAATSGALRDRFGDFTRVGNIIGTSVSAVFLLILCFGNMWVLYKLVTNLHNVLEARRQGHSGNDAGFIDSDGAARELHLDSPGFLASVFRKLFVLIDRPWKMYPLGVLFGLGFDTSSEVALLGISSIQAMRGTSGMCMLDTTDGALMMALYTSKAFSRDRVAILYYSIVLTAITVVVALFIGIVQVLNLIQNTAEPEGPFWDGLTNLSDHFDIVGGSICGLFLVVGVGSIFLYRPWRRRVERDMPAYVRSDASIPGQPDESEEGLIGDAEPLPGKKAVATTSTRAAEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLH2</accession>
    <name>A0ABR3ZLH2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GPN-loop GTPase 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_001048</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Binds to RNA polymerase II (RNAPII).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000014">
        <property type="protein sequence ID" value="KAL1900364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17871">
        <property type="entry name" value="GPN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030231">
        <property type="entry name" value="Gpn2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231:SF3">
        <property type="entry name" value="GPN-LOOP GTPASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231">
        <property type="entry name" value="XPA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1900364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="353" mass="39852" checksum="DB39B67034A2FBB7" modified="2025-10-08" version="1">MPFGQLVIGSPGAGKTTYCDGMFQFLGAIGRSCSVVNLDPANENTNYPRAIDIRDLVKLEEVMKDDKLGPNGAMLYALEELEHSFDWLEESLSALDQDYVLFDCPGQVELYTHHNSLRNIILKLQALGYRLVVVHLSDSFCLTQPSLYISNLLLSLRAMIQMDMPHINVLTKIDKVSSYDPLPLNLDYYTDVDDLSYLTPHLEKESPIMGNGRFARLNEAVANLIQSYSLVRYEILAVENKKSMMHLLRVIDRAGGYVFGGAEGANDTVWQVAMRNESSMGDDVDIQERWIDSKEEWDKMEQEQWEDQQRIAEKMAVAEGGLDTVMPDPNMTDPDFGDMKLPSNIGVKVIRKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLP8</accession>
    <name>A0ABR3ZLP8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">50S ribosomal protein L34</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_000461</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3980">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00391">
        <property type="entry name" value="Ribosomal_bL34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000271">
        <property type="entry name" value="Ribosomal_bL34"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01030">
        <property type="entry name" value="rpmH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14503:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL34M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14503">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN 34 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00468">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="139" mass="15111" checksum="DB9A21551EE52397" modified="2025-10-08" version="1">MIQRSLLTAAISAFSRPSAATAVQTALRQSSTTTNRRAFSVLSPLRPGLQIRSPLIAAFSPKPAAGATTTVADVVPTEAISASPALAMMQIRCGPRNTLNNNSRLKRKRRIGFLARKRSQTGRKILERRLAKGRMRLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMC9</accession>
    <name>A0ABR3ZMC9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Altered inheritance of mitochondria protein 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AIM11</name>
        <name evidence="6" type="ORF">Cpir12675_000592</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the AIM11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038814">
        <property type="entry name" value="AIM11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39136">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39136:SF1">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="184"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="122"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="129"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="140"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="265"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1901226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="281" mass="30031" checksum="8EF8619A181F3376" modified="2025-10-08" version="1">MPTPFLPEATVAAAVTETPQALITPPAPTRRKTPSERNATQISLFLLGTSFSLGAMFVTRRAIQRRRVSAVPQFFPSHAHVVFPERLQWAISQARTEIAHKAGGELGVKANACVPRFLLSSSRSGTNAPDTTTTIATVTSPPPPSPPPSLDPSKPSDLETLEIAAMAASISPELTRKRTDSAGLAAEAFVLATANVIAFALFCAAGFAIMLDIAEIEDIREYARRSVGRASGKTTPEEDEKAEKELESMAREFLDKFGIVSGENAGKEENGQAKNRDQGNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNP0</accession>
    <name>A0ABR3ZNP0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Calnexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_000370</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the calreticulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.250.10">
        <property type="entry name" value="Calreticulin/calnexin, P domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001580">
        <property type="entry name" value="Calret/calnex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018124">
        <property type="entry name" value="Calret/calnex_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009033">
        <property type="entry name" value="Calreticulin/calnexin_P_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11073:SF1">
        <property type="entry name" value="CALNEXIN 14D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11073">
        <property type="entry name" value="CALRETICULIN AND CALNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00262">
        <property type="entry name" value="Calreticulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00626">
        <property type="entry name" value="CALRETICULIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63887">
        <property type="entry name" value="P-domain of calnexin/calreticulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00803">
        <property type="entry name" value="CALRETICULIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00804">
        <property type="entry name" value="CALRETICULIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045011652" description="Calnexin" evidence="8">
        <location>
            <begin position="18"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="495"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="238"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="518"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="525"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="537"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1901680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="558" mass="61695" checksum="AD1A5A94FFB13110" modified="2025-10-08" version="1">MKLQSVVTAALIAAVSADDAQKPLTGEKPSSVDLPTFTSTSLKGEFIEQFTEDWDKRWKPSHAKKDIKEGEEEWAYIGEWSVEEPSVLKGMEGYKGLVVKNAAAHHAISAKFPKKIDPKGKPLVVQYEVKLQNGLECGGAYMKLLRENKALHQDEFSNTTPYVIMFGPDKCGHTNKVHFIFNHKNLKTGEYEEKHLTSPPTAKITKATELYTLIVHPNNTVIIQQNGDTVKEADLLKDFQPPVNPPAEIYDPEDSKPKDWVDEARIPDPDATKPDDWDEDAPFEIVDEDAVKPDDWLEDEPTTITDPDAIKPEDWVDEEDGDWIGPTVPNPKCAEASGCGPWSKPIKRNPDYKGPWSAPMIDNPDYKGPWEARKVPNPDAFNDTTPSNFEPMGAIGFEIWTMQKDIMFSNIYIGHSVEDARKLAEESFFPKMEGEKALEAAEKPAAKDEPKIDSASDLKFLDDPVLYATEKLDLFLALFKSDPMEAVRFVPEVPAFAAGALVIFISILSMLFGGGSAPAKKASGKKQEKKETEKKATGAATGADTGKTGATKRTAKAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNR0</accession>
    <name>A0ABR3ZNR0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosomal protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_000228</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the bacterial ribosomal protein bL36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00251">
        <property type="entry name" value="Ribosomal_bL36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052143">
        <property type="entry name" value="Mitoribosomal_bL36m"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000473">
        <property type="entry name" value="Ribosomal_bL36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035977">
        <property type="entry name" value="Ribosomal_bL36_sp"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01022">
        <property type="entry name" value="rpmJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46909">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L36, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46909:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL36M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00444">
        <property type="entry name" value="Ribosomal_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57840">
        <property type="entry name" value="Ribosomal protein L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046579256" description="Ribosomal protein" evidence="8">
        <location>
            <begin position="22"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="113" mass="12142" checksum="6386182731ECB6D6" modified="2025-10-08" version="1">MVASLLCSFRALSLRLPRAAASISPPAAVSALSQSRAISTAALSASAGTATLRANATKTVTTVVQQTRGMKVHSSVKKRCEHCKIVRRKAGKRHNGYLYVICKANPRHKQRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNW2</accession>
    <name>A0ABR3ZNW2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_000002</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF34">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR OF PROTEASES PRTT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="40"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="523"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="40"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="523"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="534"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="755" mass="81817" checksum="EBC153459C8881DF" modified="2025-10-08" version="1">MEHSATTSTASAASGSSPTSDQGDVDIKYVAHTADSAAVVSTAAPGSSDVSGPSPAPGPASAPKTSTAGGKSSEPPASGSVAAEVAAATAAGASGDQPKQRRRRRIFSCESCQRLKCRCDYDPNLQSCRRCQLLRIRCSRQDQDRLEPLPRPLAIGQASEDRIRALEDALAETQAMVKKLSSCVLNMPLDIHEHDEESPPTNTIDAGPERISDPADHAISSAPVVVIRELGSRWAMANRKRKEYAMFDLVAAQLLDAKTADELIKIFFEFRGQTYHLDIPHGLSSETMRAQSPFLHSVCCLYAMTYVPEVYATSLHQRVYEKVRLSLGQILLTSPLHLEEIQGIFLMSNNATAPSENGPEYIDSWMLTGYCAEQAMLCISFSTIVNNIKAGQTTANDRAAIRLWATICVHHLRWAATTGRPSVIPERYIEQCNTLLSFYEATMQDGMLLAEIMLYSVLFQKLGHQPQLDTSGVCLTFDPWKRKWAHLLSLQTSSMLQIGYNLACLTLCVRSLEDLGERISSSTILSSPGNMQESTPSSSGPTSNSTIPTSDPNDTRALLHLGVARSVQGVLETFLSMPHAQKISSTTNTLLAVGYCSLILAHYDAAHSHVSNEKCQELVFKYEEWCAATRGKEWALSTARLARDLLIARLHPSSAVSERGGTNGSTNSTSRRRAEYHGNFSAAHHRAMGMPPAAHGAAHSAVSADPMAIDSAAAGSGVPVGWDPDASHATYNFTQSDFPNIEDFFSGGFLDFPRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP60</accession>
    <name>A0ABR3ZP60_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7582 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000527</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056004">
        <property type="entry name" value="DUF7582"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24483">
        <property type="entry name" value="DUF7582"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7582" evidence="2">
        <location>
            <begin position="177"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="472"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="510"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="131"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="525"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="699" mass="74946" checksum="7CC2377FA93AA407" modified="2025-10-08" version="1">MTVTKLRISSPLEAGQSILDACNLPPRLCDALDHASSKLSSKGVSVKLAVALRDYQLPTLTIIPSAYSETGVYASQPPTPDYSPSSTSACSSSTSSRFGSFSNAFSSMRQRLASHVPLSLSLASTWTSESTVPSPSHSSAHTPITPMSPPPMTASTSTTFPSTIDAVSPNGPCALGIRLIQTTKVDAKTTRILNHVFNKVRAKFGIGYDMLPQITAPDACGITDTIIRRSISQDEILYGSTGLTLISLDRYYTFKSALSSFSRTGSSTRLEDAVDELRRLYLANGSRKISRCHITRSYDWLSVSDGALAEVDIMYRRAYGGVEGFGAIEGVVGTANSESNFATPSGNMPSLQHRFEHVGLNSPELTPLDEKIGVESILRSEVSTMDSRWSGSEYSSEINLPSWEEKSEVFHLANDTSFDPSYLKRASTPRPLQLHRRSTPRGTIAGLEELVPEMMAASAPVAAPNPKIITTCPASTTPPPAPTCERPPATILSRTPPPRILTRSLPRLIIPTSNSPENPPKPMDSQPQLNPQTSFPVTSTTTAPTLDEHRGFATSGAVGCIADQPGKLTETPLTSHPDNNGQLPFFTPKVFPPVTEAATDTLLPSSAIATNFYRMSYGVSNLDAKLPLGRHPHVSIAQLLDPVDPRLSMQSSTTGLGMGPITPNGAEDISPVTRGEWGFLFAGPAFVNARMVAVETCHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPD2</accession>
    <name>A0ABR3ZPD2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Annexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_000384</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="domain">
        <text evidence="4">A pair of annexin repeats may form one binding site for calcium and phospholipid.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the annexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.10">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001464">
        <property type="entry name" value="Annexin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018502">
        <property type="entry name" value="Annexin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018252">
        <property type="entry name" value="Annexin_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037104">
        <property type="entry name" value="Annexin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009117">
        <property type="entry name" value="ANX14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502">
        <property type="entry name" value="ANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502:SF102">
        <property type="entry name" value="ANNEXIN B11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00191">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00196">
        <property type="entry name" value="ANNEXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01813">
        <property type="entry name" value="ANNEXINFUNGI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00335">
        <property type="entry name" value="ANX"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47874">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00223">
        <property type="entry name" value="ANNEXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51897">
        <property type="entry name" value="ANNEXIN_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0041">Annexin</keyword>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0111">Calcium/phospholipid-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="34"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="61"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="109"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1901693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="489" mass="54003" checksum="87CEC62BA5128ED1" modified="2025-10-08" version="1">MAYHYSHQGYGQQPQYPPQGQYPPPPPSGQYPPHNQQYGQYPPSQQTQYAPPPGPPPPGQPQYGAPPGQYGAHTQYAPPPGPPSQYGAHPPGQYGAPPPASYGASGYGVPPPGQYPPPAGQYGHQQPLPGGGYPPYLPADQPSPGYGPPQVISWNADPIASACRSAMKGFGTDEKALIRALADKDPLQIEAIKQSFERQFRRNLIKDVESETSGDFQFALLAILRGPCLNDAYELHRAIIGAGTNERALNDVLLGRSNADMHAIKSMYNRTYRRNLETDVKGDLSAKTERMFMIVLGGTRADSQVQVQSHQADADAQVVYQAGEGRLGTDQIAICSLFATRNDAQIRAFADAYRRNYSKDLEDVIKKVIQIPVFNNQDTNNGIWPLANFLEKKKEFSGHMEDALLYQLRHAVSPYKNTAREIERAMAGVGTDEKALTRRIVAAHWDRNFMEGVKVEYHRMYNRDLARRIKGETRGDFERVLLACIGCAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPG4</accession>
    <name>A0ABR3ZPG4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha-1,6-mannosyltransferase Och1</fullName>
            <ecNumber evidence="4">2.4.1.232</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">och1</name>
        <name evidence="4" type="ORF">Cpir12675_000036</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.232" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033164">
        <property type="term" value="F:initiation-specific glycolipid 1,6-alpha-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007577">
        <property type="entry name" value="GlycoTrfase_DXD_sugar-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039367">
        <property type="entry name" value="Och1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31834">
        <property type="entry name" value="INITIATION-SPECIFIC ALPHA-1,6-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31834:SF1">
        <property type="entry name" value="INITIATION-SPECIFIC ALPHA-1,6-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04488">
        <property type="entry name" value="Gly_transf_sug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046577699" evidence="3">
        <location>
            <begin position="30"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="362"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="362"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1902137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="404" mass="45231" checksum="064A86C9D9DB09E6" modified="2025-10-08" version="1">MLSAKRALTGALIIIILFFLLTQTEDSAAIKSSSNSPTSQLSSASKAASSASTATNAKTNLGSKGKGSAGNIATDSQKPLMDTSKMTLREKLEYTYAYDIASKFPAYIWQTWKYTPADGEFEFREQEASWSLMHPGFIHEVITDAVAFPLIRLLYASTPEVIEAYKSLPLPVLRADFFRYLVLFARGGIYSDIDTRSLKSASEWVPKAMDRDSFGLVVGIEADPDRPDWHQWYSRRIQFCQWTIKAKPGHPVLREIIAHITEDTLKRKATGRLAHFDNKNVIEFTGPAIWTDIIMEYLNSPRYFKTSPNMPDPNVNWKNFTGMQSPRRIGDVVVLPITGFSPGVDQMGSKGVDDPTAMVSHEFEGTWKPEEERNIGKELSTEDQEAKAKPKAKSTVAERRSKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPK8</accession>
    <name>A0ABR3ZPK8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000194</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003738">
        <property type="entry name" value="SRAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02586">
        <property type="entry name" value="SRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="86" mass="9907" checksum="B03C6BB666F15EA4" modified="2025-10-08" version="1">MCGRYAQALRPSQVRRQLQEENMLINEAPENNSPDAPNITHNFAPTNQGLVCRANGTHFVRQESSDDNRITPELKTRQHYKLQTMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YAL0</accession>
    <name>A0ABR3YAL0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Karyopherin Kap95</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">kap95</name>
        <name evidence="7" type="ORF">Cpir12675_006985</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000489">
        <property type="protein sequence ID" value="KAL1885346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058584">
        <property type="entry name" value="IMB1_TNPO1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25574">
        <property type="entry name" value="TPR_IMB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="6">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1885346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="832" mass="91184" checksum="AC200670E1220AD1" modified="2025-10-08" version="1" fragment="single">PLYLQALVHELANESNQGPIRAAAGIALKNAFTARDPTRQPELQAKWLQQIDDETKGRIKAMTLETLGSSNSQAGAAAAQLISAIAALEMPREQWQDLMPSLVKNVSDGAAHLKQASLTAIGYICESQDPELRSALVQHSNAILTAVVQGARKEEPSMDVRLSAITALGDSLEFVGNNFKHEGERNYIMQVVCEATQAEDSRIQQGAFGCLNRIMALYYENMRFYMEKALFGLTIIGMKSEDEDVAKLAVEFWSTVCEEEISIEEDNLSVDSTEHMRPFYNFARVAATEVVPVLLQLLAKQDEDATDDEYNLARASYQCLSLYAQSIRSPILSHVLTFVEANIRSEDWHLRDAAVSAFGAVMEGPEEKVLEPIVRNGLGALIDMMGDSNLLVKDSTAYALGRITEACPEAIDPATHLEPLLKALFSGLATHPKMAASCCWALMNMAERFAGDISAQQNSLTPHFNQSLQQLLEMSGQPTCDSSTRTAVYEVINTFVQNSAVESMASVAQLSDVILKRLEETIPMQSQVVSVEDKITLSDIQTSLCTVLQAIIFRLDAEIAPQGDRIMQVLLQILSTVGAKSSVPEAVFASIGALSTSLNENFFKYMEAFSPFLYNALGNLEEPGLCSMAIGLVSDITRSLGAQSQPFCDQFMNYLLNNLRSSSLSNQFKPAILQCFGDIALAIEGAFETYLSVVAQVLQQAAGVEATADGSYEMIDYVISLREGIMDAWGGIIPAMKASGKATSLQPYVESIFALLNSIATNYLNRSEPLLRSSMGVIGDLAETFPNGELKEVLRQEWLTALIKETKSNREYGPRTLETARWARELVKRQIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YDL8</accession>
    <name>A0ABR3YDL8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006876</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000401">
        <property type="protein sequence ID" value="KAL1886061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01299">
        <property type="entry name" value="Met_dep_hydrolase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051781">
        <property type="entry name" value="Metallo-dep_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057744">
        <property type="entry name" value="OTAase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43135">
        <property type="entry name" value="ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43135:SF3">
        <property type="entry name" value="ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="2">
        <location>
            <begin position="211"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1886061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="633" mass="67293" checksum="53C5F8595AF22BC9" modified="2025-10-08" version="1">MDPPRPSLRPLPFPRGGGAKGGGKANYKSSSTHSVSTYSMLTSRPKPIDTAIGSATAIGSSSQSYKYVPVPIDRNPPARYCRPGVDFSRRSGSSFGLASGPPGTVAISASAPVSIPTPTISTLSATARATITKPTDNSYVRMQRRKHESRHEQRILAIHTSMLFNPRTEEVMPDVTIEVNCATGKITRMIQHDADTEVVTKTGDIDLRGKFVMPGLVDSNTHVFLHSYRERPPSAQIAAESVVERTIRATNHVRAALLAGYTTLRDLGTEGMQSYDTDLRNSISRGLAPGPRLFVATRPLTSLALDSLNDDPASCMLVDPKDRIAAVINAVRMRAAAGADVIKVYVDSPSHSFNGVGSTSTSEDEPKTPISPAAFTPTPAFTYAELRALVNEARINKLPVAAHATSADASLMAVEAGASTLEHGPINADDELFLAMRKHGCIYVPTLAALAVLNPDAMQAMQRSVRLAYDIGVTIAAGGDSGVFAHGQNARELELLIDAGMPVMAVLCAATINGYRACGGGWTQGAEASEADSSAKVGRGRGKGSIGGVGSAGVQFGWLGEGCMADIVALDADPRSDSRAFRHVDFTMKEGQIWKLDGIRTSLIFGPGMELGFPGQDEMEMGWEVVERPSWRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YF37</accession>
    <name>A0ABR3YF37_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006862</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000397">
        <property type="protein sequence ID" value="KAL1886915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF48">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1886915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="213" mass="24695" checksum="FE41BEBDC250A9A4" modified="2025-10-08" version="1">MKLVRQHICIPVPGVYNVYKDADSGHMCIVMEYMDGEQLDEVWPRLSEEQKDTVVQQLRGYFVELWQIKGSFVSRVGGSACDDQYFSITGEDCRPYKDGAELNKALVKAWSTNRKNDPLTRLLCKIQVEVMSSHEYVATRNDFDPRNILVRGSGVIAVLDREFSSIFPGYWEYCKSHWWHAWDNPWMQEDLVGRVLDPYLKEVAVILNTSYTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YF61</accession>
    <name>A0ABR3YF61_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000386">
        <property type="protein sequence ID" value="KAL1886945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038966">
        <property type="entry name" value="TMA17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40422">
        <property type="entry name" value="TRANSLATION MACHINERY-ASSOCIATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40422:SF1">
        <property type="entry name" value="TRANSLATION MACHINERY-ASSOCIATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1886945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="215" mass="22968" checksum="D1F15FA2E63696D7" modified="2025-10-08" version="1">MSTNMTADTTPITPERFSAAITELNQPTLYLKVLEIRNSIAHLVSSNAQLEEFTTGPDADPVCIEAIRENEDVISRMNNRIALIAAEIENRGISWEEFDRISAPDPSLPSGGDSATTAPTSNGVNGTVNADAGTGTGTGANIIAAAHPAWSDGTFQIGTISEDQIHMNHSGAERQSADANSGPLENAEDLQRQLQQRLAELEVENNEDNDSGMHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFM2</accession>
    <name>A0ABR3YFM2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Extracellular protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006689</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000353">
        <property type="protein sequence ID" value="KAL1887110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182:SF1">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045202056" description="Extracellular protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="340"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="414" mass="41668" checksum="7EA031E485FB5E54" modified="2025-10-08" version="1">MKSYVATALLALVGSASAHMAMTYPPPLRSKANPYAGSDIDYSITSPLDKSGSDYPCKGTLNLLGTAAATSVATWTAGQAYNMSVSGGAIHGGGSCQLSLSYDKGKTFTVIHSYVGNCPTSTTSSYDFSIPSDAVSGEALFAWTWFNEIGNREMYMNCAVVNIEGSSEAKAASVSSSAAASFSSRPQIMVANVGNGCSTTEGSDVKFPNPGPDVTDDSTNTGNPVGSCSSDSSSGSDSDSGSGYASSIPSSTASSIPSSTAAASPSTVATTSAAYVAPSSSEAISEATSKPAASVSLPGGIFLTKSEAVVTQAPSSTFVTVTRPAATSVDSPTTTGYSTAVPSSDAGSGSSSQGLQPVGLDCSNEGEWNCVDGKSFQRCASGRWSVVMNMAEGNTCRSGVSAQLIVGRVAEKCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFM3</accession>
    <name>A0ABR3YFM3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cell agglutination protein Mam3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MAM3</name>
        <name evidence="9" type="ORF">Cpir12675_006706</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000356">
        <property type="protein sequence ID" value="KAL1887086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045095">
        <property type="entry name" value="ACDP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12064">
        <property type="entry name" value="METAL TRANSPORTER CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12064:SF97">
        <property type="entry name" value="METAL TRANSPORTER CNNM-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="8">
        <location>
            <begin position="53"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1887086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="379" mass="41108" checksum="BB5D89DC8B099B3E" modified="2025-10-08" version="1">MRGRSRAVGTLSATQGSVLSMTRLLFHSVFAAAAPVINSKLSTRTVEEEEPVEGGDLVALYIFSAILVLAGGAFAGLTIALMGQDDVYLQVLAGDASEPQNKNAQRVYNLLKRGKHWVLVTLLLSNVIVNETLPVVLDRCLGGGVAAVIGSTALIVIFGEVLPQSICVRFGLQIGGFMAKPVLIMMWLMAPLSWPIAKLLDWILGEDHPTVYKKSGLKQLVNLHQTLGDVSNRLNADEVTIISAVLDLKDKPVRDVMTPMDDVFIMSEDTILDERTMDRILSAGYSRIPIHAPGSPRNFVGMLLVKILITYDPEDCSRVSDFPLATLPETRPETSCLDIVNFFQEGKSHMVVVSACPGEDHGAMGVVTLEDVIEELIGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGJ0</accession>
    <name>A0ABR3YGJ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006815</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000383">
        <property type="protein sequence ID" value="KAL1886957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1886957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="350" mass="38819" checksum="306EB310D19CD852" modified="2025-10-08" version="1">MLDLNAAYNEARITSVSPYDSMVQPQDADLVKVRLEDPSPYGLSESLIEKLELDPTIMKSAANPGKPPATNQSHNLTEYTIETINYPSLQSPRERMRVLSKDSIDAVIIMYDVTRRSSIDLAKHIYAEVQQQFGHATKKRRDRLSRPLKVAHGAPIIAFVGSKCDVDSITCEPVSLGAAKSSVSRLENLNQASRASRTSTESSQSIIIEETWRKIVNEPAKHDSPNTILDLWMRIDQYAPSVTPKPLIKSAGSCYSASYTKAPRQIPKIKGQHLSMELGADIPFFETSAKTGENVEVLFETILRAVLASRARQEASAPTRGTTGCLVLPSCTKSRRLWSRFCRKQLKSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGX4</accession>
    <name>A0ABR3YGX4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Extracellular serine-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_006714</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000358">
        <property type="protein sequence ID" value="KAL1887068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00920">
        <property type="entry name" value="Cupredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052953">
        <property type="entry name" value="Ser-rich/MCO-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883:SF15">
        <property type="entry name" value="EXTRACELLULAR SERINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883">
        <property type="entry name" value="SERINE-RICH PROTEIN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046303019" description="Extracellular serine-rich protein" evidence="3">
        <location>
            <begin position="20"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="210" mass="22143" checksum="709C7808B84FF6D7" modified="2025-10-08" version="1">MRFSSVLIAIAAATGLTSAKTIVVKLTDKNTFDPREITADSGDVLEFQFGPANHSVAMGDFNAPGGPCVPINNGGFWSGYVPVGSDLAQTAFRVKLNNTDPIVFYSTQGRECNFGMIGVVNGRDNQTYAKYAESAARIADSIDPHNGPFGGVFADRDQDKSSSSSSNNNNNNNNNSNNNNNKTNKSAAVSLQATTILVVVASLMVLAVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHB9</accession>
    <name>A0ABR3YHB9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_006438</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000300">
        <property type="protein sequence ID" value="KAL1887724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185:SF1">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="284"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="303"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="313" mass="33932" checksum="30CF3722E8E7C272" modified="2025-10-08" version="1">MKTTPAHEMNVHEPLSNFSFSDTGLENVFGKTIQGNHPQAGTSVGKMLFRDKGCTKTSVLALTKDNIETLPTLLSTYGRSSAFSGCTVLDVAKAVSAANYLSSLITLGKDNEVFIGAECGYNNPCEILIKEAEKQFPNRELIILSIGTGITKVVEISNESDSLDDALAKIAASSMATATRLRNKYHDSPIYHRFDVENGLRDTNPKIVQGAAQISAHSRNYIQENEASIMEFTGLIESATKFPLLQTEEKLVATVPPQAEGNFISPTLLPIKLTFILTTSQATFPDPKSNHQSGSPPSYSDVVSEKRPVPPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIG4</accession>
    <name>A0ABR3YIG4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutathione hydrolase</fullName>
            <ecNumber evidence="1">2.3.2.2</ecNumber>
            <ecNumber evidence="1">3.4.19.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Gamma-glutamyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Gamma-glutamyltranspeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006294</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an N-terminal (5-L-glutamyl)-[peptide] + an alpha-amino acid = 5-L-glutamyl amino acid + an N-terminal L-alpha-aminoacyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:23904"/>
            <dbReference type="Rhea" id="RHEA-COMP:9780"/>
            <dbReference type="Rhea" id="RHEA-COMP:9795"/>
            <dbReference type="ChEBI" id="CHEBI:77644"/>
            <dbReference type="ChEBI" id="CHEBI:78597"/>
            <dbReference type="ChEBI" id="CHEBI:78599"/>
            <dbReference type="ChEBI" id="CHEBI:78608"/>
            <dbReference type="EC" id="2.3.2.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:59468"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="ChEBI" id="CHEBI:143103"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>glutathione + H2O = L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:28807"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:61694"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Sulfur metabolism; glutathione metabolism.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.2" evidence="1"/>
    <dbReference type="EC" id="3.4.19.13" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000278">
        <property type="protein sequence ID" value="KAL1888111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043138">
        <property type="entry name" value="GGT_lsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000101">
        <property type="entry name" value="GGT_peptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043137">
        <property type="entry name" value="GGT_ssub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00066">
        <property type="entry name" value="g_glut_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11686">
        <property type="entry name" value="GAMMA GLUTAMYL TRANSPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11686:SF62">
        <property type="entry name" value="GLUTATHIONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01019">
        <property type="entry name" value="G_glu_transpept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01210">
        <property type="entry name" value="GGTRANSPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046421260" description="Glutathione hydrolase" evidence="2">
        <location>
            <begin position="26"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU368068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="625" mass="66766" checksum="A12D039CC6A4B6CC" modified="2025-10-08" version="1">MPACISVRAASKFLLAAALAGQTIAQAVEATEGAVASESEVCSKIGADVISKGGNAADSMVATVICVGTVAMYHSGIGGGGFMLIRSSDGNFESIDFRETAPAAAHQDMFNENAKLSEFGGLSVAVPSELRGLEYLHKKYGSKDWADLLAPSIDLARNGFVVSKDLQRYMDGSVDPEFLVEDPCWGIDFAPNGTRVVAGDIMTRKRFADTLEKVAKDGVDVFYYGEIAESTIRAVQADNGIMTMEDLDSYSLVHGEPFQVDYRGYKVTGTHAPSGSVVTMNALRVLEGYSGIDDPSQRNQSAHLLDEAIRFAYGMRTKMGDPQFTDNMTEYTQAMLSDETVRKIRSQIHLNETFPTSYYNPDGIESLPTPGTAHMSTADKSGLAISLTTTINLAFGSRLCVPETGVIMNDEMNDFSIPISSNAWGYIPSESNFIRPGKRPQSSASPIITEKDGRLDLVIGAAGGSRIISTTIQNIVNIIDRNMSCQEALSQPRMHDQLSPETIVFEPSYDNSTIEYLRSLGHNVTRIPSILTSAQALRMFPNGTFEAAGEPRQVSSGSAVAYSNGTSSSTSSFFAISSFSSSSSSSSSSPSSSPASGGVSIRPAVGLWNYYAVLATVGLLLQAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YII3</accession>
    <name>A0ABR3YII3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_006484</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000308">
        <property type="protein sequence ID" value="KAL1887591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06174">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23524:SF1">
        <property type="entry name" value="MRH DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23524">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="358"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="389"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="427"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="522"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="548"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="144"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="576" mass="60428" checksum="D5F2FF941AD67497" modified="2025-10-08" version="1">MASLRCRMRALLPFSPTITGLQAATYLLGISLFSISFLVFLNSSVSFVITDLIGRKNGVGDIVGTLGFADEAVALVMCPVWGLVSDRLGVRWVAVLGYVIVGIALVVFVQARNVYPQLLLARVFFALGATACATMVTAILPSLTDDSPPPSGSPFGSGGHEEREEETSPFSAPTAREKPPVLAGFVGLFTGCGALVALLLFLPLPARFSEQDGVSQSEAVTRSFYVVAVVALCVAGFVAVGLRGLKGEEDKGWRTLFGLESKIAENDSDGCADGSLTYISGRRPLPYLHLMRAAVRLGFVDADIGLGYLGGFVARASTVAISLFVPLFINTFFISNGFCHGSPHDPSPELKKECRTAYILASVLTGVAQLMGLVCAPLFGYLARRPGKWNIPLIISTLSGVAGYTAFPLLRSPELRDVDGRGGSRWVLVPVALMGISQIGAIVCSLGLLGRGVIDSSPSAAPFGAATIVAQTDSVPSHHDDASDAEYCEECVAEEDDCLLPGGSRAVAAASRIQLKGSIAGLYSWCGGAAILLLTKAGGYFFDVLSTGAPFYMMAGFNAMLLAAVVAVDITRLGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIL3</accession>
    <name>A0ABR3YIL3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glucose-responsive transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RGT1</name>
        <name evidence="8" type="ORF">Cpir12675_006477</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000307">
        <property type="protein sequence ID" value="KAL1887621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF26">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="356"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="212"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="426"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="886"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="153"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="481"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="890"/>
            <end position="903"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1887621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="988" mass="106992" checksum="C18AF1BE83F14A0F" modified="2025-10-08" version="1">MSLKPNNWPPHLTYIPAPKYSPQLSKDQAKALAVCPDGLIKVPDEICRLPSTLAKIVLISDAKHPANGQAGLFATKNLKPGAPILLYLGVVHPPDTAHETSDYDLWLDHDLEIAVDAATIGNEARFINDYRGIKHRPNAEFREVWSSRETRPQGASGSSTAAQPPPIVLGQADPNPDYGNAVVAGVEVGITSQSHSRSSAQTQIPPSIAPEAPMHHAGHILPDISSRSPHLAGQLQPQLPQPPAPTVFPAHRHPHTIANLQLAAQLGSGLTTESVMQQVSAGHALSTHAHASGDPSLRSILPQNETSTERHYAIDESQIATDGQHLSGLPTNVTQDLQYGQDMEHLGRKRPKASRACDECRRKKIKCDAQLDTGTIPCTNCRRGKALCLFSRVPQKRGPNKGYIRELADRISGIEDKLVMERSLKRPCTDIAGEDDTPSTAGKENGWPESRSPISLSNNQRPPPLYANQGLAPVPSSLAGQPTPAQPATASPETQVSRSCSTIDGLACNNPGTALGVSALNINQQVMDGYLVTIHGLLPFLPDTLSGLEIHLLQCPIMLREAFTNALFAAVHSFPTFDHIPAGDLVQANLKLVMWQLSDTSTQAGIKTVLSTSTLVYLQTLLLLAVQADNRPVGEHGVDKTEILGRAVSTALSAKIYMFHPAEGQPDDTNKAMRIRVWWCLVIMDRWHAIGFGTQSLIREEHTMASNVLQDILPANLYHLARLNPLLNLACTIITYMTDMLASGAKPHPAEIALSSTLIPWAERFREDLPPGFTPATHPTLFLVYWHARLLAHLLDLRVTAGTLVWPCRELVAIIISPMHAEHNALLTALTRHTIVLTSLVLRLLARSGSTPVAEEATRLVLDLTTSTGWAADMVRVTVDAGDAAAAEAPDCREQRGKEESREAVSSSVAGSGLASASLPLKIMADITDTSDKNGANWSETLPQESKVATPHVTYENLAFDPRPLLQAGYLAFARNERANNSNEYPWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIV6</accession>
    <name>A0ABR3YIV6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fumarylacetoacetase-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_006414</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000297">
        <property type="protein sequence ID" value="KAL1887782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820">
        <property type="entry name" value="ACYLPYRUVASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820:SF7">
        <property type="entry name" value="ACYLPYRUVASE FAHD1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="3">
        <location>
            <begin position="21"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="242" mass="26044" checksum="A61C8A2AB25C1655" modified="2025-10-08" version="1">MFALRRGFATAAARSLQAPSKVVCVGRNYADHISELSSARPKQPFFFLKPPSSVLLPGAGPVIRPNGVDLHYEVELALVIGKTLRNLEASEETAALEAIESYLLTIDLTARNIQGEAKKKGLPWDIAKGFDTFLPISRTIAKSAIPNPHNVELFLQINGQTKQAANTNLMLFQIPRLLSDISKVMTLTPGDIVLTGTPAGVGPVVGGDVMRCGLKVDGRELEAAKIEVSVEDSTSTYVYAET</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIX9</accession>
    <name>A0ABR3YIX9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosome biogenesis protein ERB1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Eukaryotic ribosome biogenesis protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 10" type="primary">ERB1</name>
        <name evidence="10" type="ORF">Cpir12675_006260</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat BOP1/ERB1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000272">
        <property type="protein sequence ID" value="KAL1888211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03027">
        <property type="entry name" value="BOP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028598">
        <property type="entry name" value="BOP1/Erb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012953">
        <property type="entry name" value="BOP1_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17605:SF0">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BOP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17605">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BOP1 BLOCK OF PROLIFERATION 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08145">
        <property type="entry name" value="BOP1NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01035">
        <property type="entry name" value="BOP1NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="BOP1 N-terminal" evidence="9">
        <location>
            <begin position="163"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="432"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="535"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="65"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1888211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="786" mass="88439" checksum="9718A550B4C04D77" modified="2025-10-08" version="1">MGSKVVTRKRKVEAAAAEPESDSEFGDGHLEGILSQSESESDDDNDESPDGPGYNSDSEEKNLESDPDVSEPEDNTEETTETPNTTTTELVSRPRRDAQPFTNEFDDPTFGQPKDVETNYRITTDANGGVRYEYDEIDPVYDSDDTDANEPANTIGDIPLSFYDTYPHIGYDINGKKIMRPAAGEALDALLDSIEVPKGWTGLTDPATGKPLQLSEDELELLKRIQLNEMPEDGYDQYPDTIEYFTSIEEKMPLSAAPEPKRRFVPSKHEAKRVAKLVRAIRDGRILPYKPESERQKDEEEEEEKFFDLWANEKEREEHIMHIPAPKLPPPGYDLSYNPPPEFLPTKEEREAWEKQDPEEREKEYLPQRYASLRKVPGYGDFVKERFERLLDLYLAPRVRKNRLNIDPDSLLPKLPSPEDLRPFPTTCQTIFRASDARVRTVAASPDGEWVASGGDDGYVRVFDLNGHLEWQARLSTEEPVDCVRWRPVKDTMVIAAAAGEDVFLMVPLDVCSVETEAASRAAIDAGFGYATGGKQTGASTTASGERKDPPGKWARPGSKLEAQGVLVKVTVRSAVKTVSWHRRGDFFCTVSPTGQRSAVAIHTLSKHLTQVPFRRLLGLAQAAHFHPSRPFFFVATQRMIRCYDLQRQELVKVLQPGARWISSFDIHPGGDNVIVGSYDRRLLWHDMDLSARPYKTMRFHPQAVRAVRFHRGGFPLFADASDDGTIQVFHGKVVADLMENPTIVPVKVLRGHKVINKLGVMDVDWHSKHPWCMSAGADGTCRLWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJB3</accession>
    <name>A0ABR3YJB3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cerato-platanin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_006510</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cerato-platanin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000312">
        <property type="protein sequence ID" value="KAL1887524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010829">
        <property type="entry name" value="Cerato-platanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38850">
        <property type="entry name" value="CERATO-PLATANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38850:SF2">
        <property type="entry name" value="CERATO-PLATANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07249">
        <property type="entry name" value="Cerato-platanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046932965" description="Cerato-platanin" evidence="5">
        <location>
            <begin position="22"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="241"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="249"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="312" mass="32944" checksum="E6D591B2A16B0DFD" modified="2025-10-08" version="1">MPLTLRQLGLGFFAYIAPGLADSGTVFATPHDTYSSSIGVLGCYIDTDRVAYWPASVSCNNICVSLTYNQTRTVNLLRIDQSQGAYDISYDAWNYLLTGDSAAKSPISGGPVEMEYKDVDASECADLIHTEDSRLPLSASNSINFLASCLEQEDSHIAQNYVLYNLLDATCQWGYDETCELVDFPAQNQPQCSHGLGTPIPCTSLPVYNLMYPTGEKVRVGDPVPAVNANATYNSYTVPTSGSSINTESSYTSGHSSSNSGSSSDSGSSSDSGSSSSSSIPDGPQSAGWGLRPAWAIMAASFAATAAVAVLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJG4</accession>
    <name>A0ABR3YJG4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7896 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006167</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000261">
        <property type="protein sequence ID" value="KAL1888456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057218">
        <property type="entry name" value="DUF7896"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42031">
        <property type="entry name" value="KEY LIME PATHOGENICITY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42031:SF1">
        <property type="entry name" value="KEY LIME PATHOGENICITY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25438">
        <property type="entry name" value="DUF7896"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7896" evidence="2">
        <location>
            <begin position="367"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="415"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="475"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="497" mass="54333" checksum="591EFCAE193A0CC9" modified="2025-10-08" version="1">MNMAMSPNSSPSSCSVGSKRNSDGAIVNSTGNSNSELASALAAASTGGILFEGQTSMMPHYNPPIGASLQMVSNTLPNVSNAYFLDANNFGCMEMLSSASMMPPSMESSYHSSWHSASTDNDMPTATSLPFSEDHTVYLAQTNSMTSSDNMMPFFMPSSTISSQDKLTMGAFGDQLGNVDFDAELMEQPVKRRAIEVSFAAEATREFHPEHMQRSESIESRFSAASDFSMSPFSSLSHQQMYQQELRGNRRHIQNGIRNSNIWPKPDDSKANWPAAYGMANRQPGNTGRASLLEQSEDSISTPVSSTATAIPVPVPARTTTTVSVSASYARPARQRVYCRHCTEQPAGFRGDHELRRHCAARHEARVKKWRCIEPEGDAIQPINPISECKACRAGKLYGADYNALAHLRRAHFQVKKPRGRANTGESQRDAVAKTPSNKPSSVDLRPYLQVLSVPSSSNDAEDSLEMESEAQAEMLTGSHWDSLEDEPDQSLFPFEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJH8</accession>
    <name>A0ABR3YJH8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Palmitoyltransferase</fullName>
            <ecNumber evidence="10">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SWF1</name>
        <name evidence="12" type="ORF">Cpir12675_006287</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="10"/>
    <dbReference type="EMBL" id="JAWDJO010000277">
        <property type="protein sequence ID" value="KAL1888120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883:SF288">
        <property type="entry name" value="PALMITOYLTRANSFERASE SWF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10 12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="159"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="11">
        <location>
            <begin position="51"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1888120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="323" mass="37641" checksum="3DC33E6B4ACFA6F1" modified="2025-10-08" version="1">MSMVNRLLGSVAAVLPYLFLYLAAFVDPGYITPENHFYHMEQYPYDFSAFHPGKFCHTCRLLKPPRSKHCSVCKKCVAKMDHHCIFINKCVGQRNHRYFVLLLLSTAVLASYGGILGFSILKDKILIRYPLWSPWKPAGMTWRDYMLIWSWGLEHNTRIGAVSLLAILCSPMVWAFLFYTVFLIYCGTTTNESLKWSDWRLEMKEGFVFKRAMSLTREKYLSVEPAITRWPVETEQIIVRTADGSLPDPQCPGAGEWERVHSLRDIDNIYDLGFADNLRDIFFDNYQFRERDRQRELWDAKNGLPPFDSTSHRRKRRAKAAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK75</accession>
    <name>A0ABR3YK75_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_006106</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the putative lipase ROG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000252">
        <property type="protein sequence ID" value="KAL1888617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007751">
        <property type="entry name" value="DUF676_lipase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044294">
        <property type="entry name" value="Lipase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482:SF62">
        <property type="entry name" value="LIPASE ROG1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482">
        <property type="entry name" value="LIPASE ROG1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05057">
        <property type="entry name" value="DUF676"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF676" evidence="4">
        <location>
            <begin position="318"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="DUF676" evidence="4">
        <location>
            <begin position="571"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="177"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="283"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="356"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="431"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="522"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="757"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="887"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="977"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1131"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="177"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="283"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="356"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="368"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="390"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="455"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="522"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="783"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="894"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="982"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1044"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1132"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1200"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1230"/>
            <end position="1245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1256"/>
            <end position="1273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1281"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1315"/>
            <end position="1336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1888617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1369" mass="149295" checksum="4CC453D00AEA9AA0" modified="2025-10-08" version="1">MLLLLQSGSVKLGDVVRYTITYTPSQDRILPSPEKLYLRIRNTSTIALRAAFVHGPYSLSVSAYPATFDPYTKFANARQYGVPQFEPMVKAGGSWECELTVPENIRQTAGMGHHPANDMSGADVFNESVIWIVEVTSQVLFSTSASVGYEVILGREKKSLNLSYATAVAAADHSLNHTVSDHSGNGSTQQNNHNHNHNNSQHHHHHHHHHHARSRSTPPGGIFSRAVRITVEDTAALWNKPHIPGWSDVGKDRMRLAEELREEEGKTPVAVVATPDIAIATTNTPPIATTADPGTTPPTMNSSHKEPLPSRTTNKRKKKKIHLVILTHGLHSNLSADMLFLKESIDAAAKKARADAKVRKAQERQARQSRVSVEHSTNTRDPVLAGCDGESNKMDLQDGDVKKPSPMQYNKKPAEQVQSEVLGERVASQVNANKKTDDKANGNPSTSGHIKNGTDEPDEEEDDDEEVVVKGYSGNATRTERGIKYLGKRLARYVLALTYPDQPYHPIISRGAGESLANAFKGNRENKTDKGGSPKSDKGSLKAKNTMYSKSAAAELLSNHALPDMDLPYKITSISFLGHSLGGLIQTYAVAYIQKHSPRFFELIRPINFVALATPFLGLSNENPMYVKFALDFGLVGRTGQDLGLTWRPPTLARSGWSAIVSNLGETAHKRVLGESQPESKPLLRILPTGPAHIALRKFRNRTVYSNVVNDGIVPLRTSCLLFLDWQGLGRVEKARRDAGLVETVVALGWAELTGTSMNHGRSLLPPPEDEDNDETTSTKTNEGSRCDRNDTKSVDGAPLTPLLGEQDKQHEVPQPSNQAIMEDGQQSMQTVHSPSSHEPQTQALDVAATGLASPFSGLFALFRSGEQNKPHGPSSKQKLIYRRSQTVPMGEETPSGADSTTSTTSSPGPGHTQSRVTTGAEFEGDGNGLSAPPRTTVFESARDLINPKMPDVPHLIDPAKRSRTIFHDRVYHPEDIPLPPIKRRHTKRKSLTHCGLSPNKKCENAPSSPRLASATTVRAPAPLSVNGSGGLSEATNVSVSGAKDIKEKSPQKAEPQTAKDRPEFDLSHMRVEEKIARAYHRDLSWRKVLVKLEPDAHNNIIVRRMFPNAYGWPVIQHLVETHFSDSASARLSDDCENSKERAMNPHMPPAKNGIETNKYDTPVSTSSGSSSPDFQLHHTSPTHPQPRLNIKTSGLYRSATETAEASDSVSVLPPLNRTNRHSRQDSLPTSPSSATTSSFISTTTAENSGTGAAVWDHRDSMTWSDRDWHDSEPDSETGYLSPLSPSSPLNVHAPAVDFPPSSGAGMRAEVPPKNATSATSVESQDQLVAQSQGQVNGKARTHYDASWSWTEAIVGKRHAKSADGRKVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKL3</accession>
    <name>A0ABR3YKL3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Clr5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006017</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000241">
        <property type="protein sequence ID" value="KAL1888863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025676">
        <property type="entry name" value="Clr5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788:SF3">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14420">
        <property type="entry name" value="Clr5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clr5" evidence="2">
        <location>
            <begin position="575"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="498"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="548"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1081" mass="119919" checksum="BC993E7C8602031E" modified="2025-10-08" version="1">MFHNSFYQQNGGDQFQNPINFNPHNNQQNGLNLDANGFDFMTGFDALSPSTMDMNGLASNMPMSNVASDQGTLPATQGVSNLIARFENPTGNHIPLKRKPTSPQGSQQLPPRPPQPTTTHVMMQKQQQSHQPMNHQQRHMSQSSQTMDIAMSSPVHARESALLYQNQAAELGAMAMKQESFGLALKPRQGSQQFPVNINSPANIMASSTINNPSNRNGFNSMLGAPNDPFSPILSSPQAQIRSPVAADPFAALNPVRMTSPLSADQVSYGMTFTNQTTTPISPTNVNIFGDVKTPSQEHVNINAVTSSFNNIQSASSFPDPFGQDLISFASIDGSDMNGMADNGLGTIDNTAFMNDRMRTDSLSYQMNSMPVTNNNFFMGQQQQQQQQQNNSVNPTQPQAPSLPQSHQHSRFPGSMPTPEPSNGSTPGFNIWKPPVQKTHKAPPLPTRPSTAVAPQFLTAQKTAGGDTIMGQPIPILQQQIQQQQQQQQQQQQQQQQQQQQQQQQQTSEETPPKKPPRPKPMSMSKSPIDPAPPTNQGSSNAPALRFSSHESAKEKPAPPPRPTSSKPTREQVPAETWENHKTLIRQLYLDERRPLKEVMQLMADRHNFRATPKMYKTRFSQWGFAKNNTEEEVKRLLSIKFQRDAEGKTSEFVRNGRVVNIRTYLKRKGKTEYDLYDFEAHANLPGHTRCRTPPPLPNLPGHMAADVKRFQEVITGNMHKALLMCKESQANITVPWSSTMLWGAVSSDIIWSANEHMKRGAPDRGVAVLNDAFTYLNNELKSMSPQVIKELLLGLVNGDPAMVTALSKFFSAWTAKNLERSHPLRPIFTALYSILQEHGAQTLSDLIWSTMPSFIDDLEAIYGRKHPYVAGSLLDLSELAEDQHLRLQHLQPDQTLEEYRSRVTHLITELHPVLENIESVEGIQSTDATALRYMLLQMQHSVMPGTSTTHVAAADLYRQMRQTGRLFQIQYAATGLFCYHEPIKVTPSMRRCRHRYDSVAKLLQMHENLAISFYFEEDMHNADHALTNSDVSHHLPYDGNAGGGSNGNDSGNGNGSNAALAAAFEMQTLGGGLGGGFAWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLD8</accession>
    <name>A0ABR3YLD8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GH18 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000273">
        <property type="protein sequence ID" value="KAL1888199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH18" evidence="1">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="116" mass="12643" checksum="210AA3BE32C851FC" modified="2025-10-08" version="1" fragment="single">MTAGITHVIMAFADSLVFTTDPIGNYEPHMKLNTVGEMFDENVKISMSIGGWDDTVGFREGARSPEARALYTKNIADTYPGGNGANYKQVPNDTSEIEAYPLLLAEIKNAIGDKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLP1</accession>
    <name>A0ABR3YLP1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005869</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000225">
        <property type="protein sequence ID" value="KAL1889223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046306852" evidence="1">
        <location>
            <begin position="21"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="372" mass="41170" checksum="D648A229C1719DC2" modified="2025-10-08" version="1">MKIFVHLAVATVFCGGISDAQLVAQDFSIVQTCETRSIFDTIPVGSFEPSDAAWDAQSQLLYVVDDNGRLASIPGYYLHEAIEDSFPQHPRNQEVLLSDMPSSKDVKIWSITHGMDLEGCAVDHEFPDLVYLGVENPAEIIAFNVTASAIQHRYAVDTYFVDDPALFTSRGNELKKHKKNRHKKGKDKAQNTGLESLAFYPGLTPGAAPRLLAGRQSDSNVFVFELVADRSSVKFVGSVNPPGPGRDLSAISVFLGKVYFVFDKEFEAISVPVRQFEAAIKPPKRLVLGESNAKKYEKDTPEWVVQRYEFDIRGQEGFAFAYSSFACALGSKDCSGIGETPVVYAIDPPRKPKLEKDILVGSFSQLQQCWRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN03</accession>
    <name>A0ABR3YN03_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAR1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005868</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000225">
        <property type="protein sequence ID" value="KAL1889222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47718">
        <property type="entry name" value="OS01G0519700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="527"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="131"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="534"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="550"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="610" mass="65412" checksum="5EA5023117085C32" modified="2025-10-08" version="1">MDPTQQRVKIHVQEQSAPVQGPTGESAAVSQVDVAVLAAVASASASVSAPPTPVLSVPATEAPVPILPIKAAAPPAPAPVADATVAAVAETAVETPDAVTSPVPGSQDDVLDHSRLETASVLSTPRVLIEQQQQQQKSRSQPQPVPIFNMGPAPTPEMMSSAMSSLRPMQNTSPAPQSQFQPHQMSHAQYVQLASEQQQQQQQHAEALRTQVLTHAQVQVAASQARAQAEAHHAHNQVQVQSQLQSQAQAQAQAQAQAQAQAQAQAQAQAQAQLQGRISEQMSSQDSMTSTGVMIPAPPHPYLPNDPTGRSVPANPYHPLIGHSFENIKDARKALDAYAESAGYKMCVMKTLPTAVVWRCSQNGRRRTRPPTTTHPSKQRKHRLKERSGCRWKIRAVKRPRLRDGEGSEPPAVEWIWTIRESDNPDARTHNHEMMDPASFASYRMKAAVSVKDIIFTMVDAGVKPIHIVAELKGRAKALNRSALSSIKSRDIHNLVQARKQRGGDGLGMGLGNEIDMDMALGSAAHDDANHEGEDLDDMDEHTDVDEEVASQSPQPQNESQRLVNPEIGSALRHETTEADVQASVAAAAAAVAAASVTDPRLRSSQVGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN59</accession>
    <name>A0ABR3YN59_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Acetyl-coenzyme A transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_005856</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000223">
        <property type="protein sequence ID" value="KAL1889290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024371">
        <property type="entry name" value="AcetylCoA_trans_1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004752">
        <property type="entry name" value="AmpG_permease/AT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12778:SF9">
        <property type="entry name" value="ACETYL-COENZYME A TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 33 ACETYL-COA TRANSPORTER -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13000">
        <property type="entry name" value="Acatn"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="429"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="458"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="497"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="576"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="620" mass="68442" checksum="5B9DC0791ECA683C" modified="2025-10-08" version="1">MGSHRLQRGKSSKSTGGTPLTNLAHQRSDSPSPSLSEGPYDSATTETVRGRSRTKKKSLNAKNSALSITTAGNMSSGIELRRKNANNEITPGSVANSHIARGNFSLDEPAPKTPTMNNHGFFELPASDQRNFGLLVLLYFLQGVPMGLATGSVPFLLKNHMSYSQIGIFSLASYPYSLKLFWSPIVDACWSPKLGRRKSWILPIQMLSGIGMLWLGSTVEEMMKGIGKSGGPTVWSFTGWWFFLVLMCATQDIAVDGWALTLLTPGNVSYASTAQTVGLTAGQFLSYTVFLALNSSEFANRWFRTVPSNEGLVTLSGYLGFWGWTYLLVTLGLGLLKKEERTCNEDGIWDVYRIMWGVLKLRNIQTIIVVHLIAKIGFQANDAVTNLKLLDKGFGKENMALTVLIDFPFEIGLGYYAGKWSQEYTPMRLWCWAFMGRLLAAVMAQVTISIFPDTGVEPWYMLVVILEHIFSTFTNTVMFVAISAFHARVADPVIGGTYMTLLATVCNLGGTFPRFFILSLVDTFTVATCHPPTSLSTVEATALGKKLITESFSCALQADKELCMAGGGACEIEQDGYYMVNMMCVLFGLFTFVYFIRQRVLYLQSLPLRAWRLVAGMNKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNR4</accession>
    <name>A0ABR3YNR4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Chromosome transmission fidelity protein 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_005571</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the CTF8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000198">
        <property type="protein sequence ID" value="KAL1890005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018607">
        <property type="entry name" value="Ctf8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28605:SF1">
        <property type="entry name" value="CHROMOSOME TRANSMISSION FIDELITY FACTOR 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28605">
        <property type="entry name" value="CTF8, CHROMOSOME TRANSMISSION FIDELITY FACTOR 8 HOMOLOG (S. CEREVISIAE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09696">
        <property type="entry name" value="Ctf8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1890005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="148" mass="16569" checksum="7A11A250D24AF877" modified="2025-10-08" version="1">MDSKSIKIYPPEKSRSSCSNPLPTTIQTPSGLAIIELQGTITHTDELSAKLHDEQDVTDALDVGHIAFPNYNPGIQEEGSMSWMKTVYMFVGGHQRLLGEVKKLPQPVAIVRKRRFSNDSPQTEEVLDIVEIIKYKIVFPHRPEPVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP22</accession>
    <name>A0ABR3YP22_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_005723</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000211">
        <property type="protein sequence ID" value="KAL1889601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF40">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="282"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="147"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="240"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="102"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="244"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1889601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="878" mass="96500" checksum="FCE16331250DD27B" modified="2025-10-08" version="1">MADDSSPMSTTPSGPVDSVLRTQDHAQQAVAAAVAVAAAAAATAAVENVESSETPLKQELLAQPQQATHVNEPHQEHEENQRDAATTAHVYATNGLQVLQAASDAQAQLLQAEHEAQQQQQQQQRQQQQQQQQQQQQQQQAQTQQQQQNDAAAQFSASLAKQHDGATDQFPTVLSKQENDPPSHFPAPLSSIPTDLPNDQDLSAASIAAAYQAASAVAAASNPSITASTPAPVPVMQMTPAVGTPTPAETSTPTPQMVVSQPVSGRGLRDGINPKLTRLSRACDHCSERKVKCEQQRPCRPCLEIGLECTNSRERKRRGPPNKSVQRIIARAQAQAQETPMATPQISLLNLGSQPNILLQQQQHHLQQQKQPVNSGLAPGAPKLDAEMIAPMPILKLLVDDFFTYVHPLCPFPHESSFYASLANRDDRTNPEFLGLLCSMIAALVASFPRNARAQLKGHQDLPRAFTFIEKCTNLALLARGPMWHNKSPKTIHDAATSYFLSLSAAYTFRLALHKELLVESLSVLERLADYKTANGAPQYGTNVCTPDTLSFNHVNDQMGKRLFWCAFLGVRSMRQIGVPLKISDIPPPTPNNPYPDLPENTEDKNILASSIDQEMEPVTMMTGFRIATDIYMTMNPIVAVEHCYGMATLGWAAQREMIKSALSAVKDIVLRLPLELQVGHTIQGGDAASDDVLAQYVSASAPAIAHPREVAQLIEANPARRRQLQFEIQKANIYVSELATRSYFVEMYFTRRQIHIAEVKATEESEDKTEETSVLAAMMQERRQIVMDLKNVLASVQQLHLEPNGASLMNKIRQVASTLAQHADSTADRESLHQLVQVLMRLENAVGGDEESELRTWAELREYREQFLGHDGFAANY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP31</accession>
    <name>A0ABR3YP31_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="9">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">srs2</name>
        <name evidence="15" type="ORF">Cpir12675_005719</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000210">
        <property type="protein sequence ID" value="KAL1889616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17932">
        <property type="entry name" value="DEXQc_UvrD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18807">
        <property type="entry name" value="SF1_C_UvrD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.486.10">
        <property type="entry name" value="PCRA, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070:SF2">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE SRS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51217">
        <property type="entry name" value="UVRD_HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 11 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 11 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="13">
        <location>
            <begin position="16"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="14">
        <location>
            <begin position="307"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="732"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="842"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="931"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1025"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="733"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="775"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="847"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="860"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="882"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="931"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1889616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1051" mass="117641" checksum="C9099C42C9796542" modified="2025-10-08" version="1">MSSSNSSHTRNVSILKGLNRQQHRAVSSRSSTVAILAGPGCGKTHTLTSRVAYLVDHIGYQPWNIIVATFTVKAAREMRERIGKHLGEERQRKIVLGTFHGLAARYLAIYGHLIGIPKKFSIMDDSDSRAVIKRICKRLNLDDIDPRAVLGFISKEKSRSPYFDGEEECEIPSTQTRVNASGMTVKKPHKPPNYVKIYSEYQAYLTETDMLDYDDLLVRCVELLQKHPRCVANVEAVLIDEYQDTNGMQYELLKQLASARNRITVVGDPDQSIYGWRAAEIRNLKRLLVEFPGTEEISLEENYRSSTRIVDTAIEVIKQDSQRYDKSLLPVHGKGTAPALRRLATAKDQADWLAMEICRIVDMTAKTLKLDDIAILLRSSSASRLIEAALIKKRIKYRMVGGRKFFERAEIKLIIDYLCVINQPKNNDAVSRILNTPKRGFGAKSLGDLLLEAEGSKVPLWELLLKHARRDRKCSISFSKNQEQELYKLIGLINNGRTRLRLGAEGKPFDLVKLIDYIIRTIKLQEYIQKTYKEDHETRWSNVEEFVKNVREFVDSASMEDETLPENEGVQQQNQLDMLDRFLTNIALVSEPYQENQDDEDPDKKNLGTVTISTIHAAKGLEWPVVFVPNVHNGSIPNSRVQDVAEERRLLYVAMTRAKAILYLSFPARDKSWSGDWVSCEMTYFLSNTHTMFAHRGPSFTRDALSGMGEILGRSFPTVDYIYKNLPEMAITEDDHYPETPSSKRPDTEFQGDGNKDNGDNKSSKRMRTELRSGGITNPNMNWETGYSTTMQQSTNFTVGFVSASSHHATLSSQGPTIAANKMPQLIAAKQNGSRTLVDMGFKDSRSAPQNPISATKPRTTSTSALGTGTSKTQNRTPGICYPSAAAKPQSASSSLSTSYLPPPKPADVEPELTKHSLGTTRGAVRTYSTMPAPTSRLKNPMQSPDKFPQKKGVYPQFSSSPVRPESHQPPAEGADADPYDHVVVDKPAETLHRTTMTTGFGGFHRPSRINRIGNPQTINRISKLSQPGVVPGAKNKNTPYKKLTIPGQDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPN0</accession>
    <name>A0ABR3YPN0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RHO1 GDP-GTP exchange protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ROM2</name>
        <name evidence="6" type="ORF">Cpir12675_005627</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000203">
        <property type="protein sequence ID" value="KAL1889830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04435">
        <property type="entry name" value="DEP_fRom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001180">
        <property type="entry name" value="CNH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000591">
        <property type="entry name" value="DEP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041675">
        <property type="entry name" value="PH_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052233">
        <property type="entry name" value="Rho-type_GEFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46572">
        <property type="entry name" value="RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46572:SF2">
        <property type="entry name" value="RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00780">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00610">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15405">
        <property type="entry name" value="PH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00036">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00049">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50219">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="4">
        <location>
            <begin position="599"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="domain" description="CNH" evidence="5">
        <location>
            <begin position="974"/>
            <end position="1267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="384"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1296"/>
            <end position="1328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="225"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="253"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="274"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="316"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1301"/>
            <end position="1320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1889830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1328" mass="149909" checksum="1D14032EAA75EA04" modified="2025-10-08" version="1">MSEYRPHDRGHQPPGRAPPPQQYQQRDAAFSNIFGAAPPPGRSHTMSSSVPPPNFGPADFHDPRRVPPPPIPQQYQQQQQQQSHQHHHQQQQQGHAPQQRPPDPPYPHRDQPLARGQQHPPHPQQQQRADSAGYHVPNPLAQYQHARRPVGPPPQGGYQQMGHSQQQRADPHAMPPSQVANSRTAAQRFHQGGGPAPAMNHDQYRTQSLASTARPQMYQQTPYGHQQSGPQHPQQPHQRPPQLQPTGYQHDGPQFQPFNANAAAQARTTAHGRVVPERNDERAMSMTGAYYPADRDSHQTMSGRVIPNRRPADAQPPQNYPSNGYNPPRSSYGKPSQPSHGSSNSGGGYSAPGTATRTASMASSVGDASARTFSMASSIAPTIVGSEQDSQVAYRSSTGKQTSENGERPQTAKVRPPIVYPALLSRVADCLRRRIITSERMKNGLSYKDAFSGADAVDVLSYIIRTTDRNLALLLGRALDAQKFFHDVTYEHRLRDSSNEMYQFKEVEGEEKSSVNGVFVLLSECYSPTCTRDQLCYSIACPRRLEQVSRLNLKIRPGLKKEQDNAVVEDDVDQTDEQKLWINSVPQEIVDSVGDRERKRQEIISELCYTERDFVKDLEYLRDFWIIPLRSRGSPIPAERRDAVVSNIFSNAIDHPSIHGVSSRFAKALTERQQKNPVVSNVGDIFLEFVPQFEPFIIYGSKQMEAKYYFEGEKSANANFCKFVDEIERRKESRKLELNGYLTKPTTRLARYPLLLDNVIKYTEDGNKDKEDLPKVLTYIRDLLSRVNAESGKAENRFNLRRLDEQLKFRPNERVDLRLREEGRELVFKCQLKKSPTDPSDINAFLFDHAVLLVKIKQVGKIEEYKAYRRPIPLELLSIREMEEVIPENNGTVKRSSSSILPALRNEGGGKKGEGWPITFRHLGKNGYELQLFASNQAARKKWLEFIDTSQVRLRGRADFFTETIISYNFFGVGNHVNCVTPFDGGRKLIYGTDNGIYMSDRKLKDAQPRRVLEAFSVTQIDVLEEYSMLLVLSNKSLVLYNLSALDPNEQAASRRPRKIQSHCNFFKTGICMGRHLVCCVKSSALSTTIKVYEPNDAASKGKKQKGLGKMFSAGQDDLKPFKEFYIPTESSSVHFLKSKLCVACARGFEVVDLETLETQSLLDQADTSLDFVSRKEGVRPTHIERLNGEFLLNYSDFSFFVNKHGWRARPDWKIDWEGMPTNFALSPPWILAFESNFIELRNIENGFVHIVPHKNIRMLHSSSHEILFAYEDERGYDVVDSLDFWKSNRRSELPPGGLGAIQAPPTASAPAAQGGAPQVPRLPKLDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRM8</accession>
    <name>A0ABR3YRM8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">pyridoxal 5'-phosphate synthase (glutamine hydrolyzing)</fullName>
            <ecNumber evidence="3">4.3.3.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SNZ1</name>
        <name evidence="10" type="ORF">Cpir12675_005580</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>aldehydo-D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = pyridoxal 5'-phosphate + L-glutamate + phosphate + 3 H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:31507"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="4.3.3.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the PdxS/SNZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.6" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000198">
        <property type="protein sequence ID" value="KAL1890014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036381">
        <property type="term" value="F:pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04727">
        <property type="entry name" value="pdxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01824">
        <property type="entry name" value="PdxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001852">
        <property type="entry name" value="PdxS/SNZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033755">
        <property type="entry name" value="PdxS/SNZ_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003215">
        <property type="entry name" value="PRK04180.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00343">
        <property type="entry name" value="pyridoxal 5'-phosphate synthase lyase subunit PdxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31829">
        <property type="entry name" value="PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNZ1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31829:SF0">
        <property type="entry name" value="PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNZ1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01680">
        <property type="entry name" value="SOR_SNZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029271">
        <property type="entry name" value="Pdx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01235">
        <property type="entry name" value="PDXS_SNZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51129">
        <property type="entry name" value="PDXS_SNZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0704">Schiff base</keyword>
    <feature type="domain" description="PdxS/SNZ N-terminal" evidence="9">
        <location>
            <begin position="19"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="310" mass="32438" checksum="91A42193C7185663" modified="2025-10-08" version="1">MSGLPSVINIGSDAVNSKFSVKAGLSQMLKGGVIMDVTNVEQAVIAEEAGACAVMALERVPADIRKDGGVARMSDPGMIREIQEAVTIPVMAKARIGHFVECQILESLGVDYIDESEVLTMADRDAHIEKNDFQVPFVCGCRNLGEALRRIAEGAAMIRTKGEAGTGDVVEAVTHVKTLKRDIARAKAVLADEGMPGIRALAREIGVDATLLKQTAELGRLPVVNFAAGGVATPADAALMMQLGCDGVFVGSGIFKSGDPAKRAKAIVRATTHFNDAAVLAECSAGLGEAMVGINCDSMKPEEKYAGRGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRT3</accession>
    <name>A0ABR3YRT3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000179">
        <property type="protein sequence ID" value="KAL1890578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="316" mass="34765" checksum="20CC29EC302C8A70" modified="2025-10-08" version="1">MTEVLNKAIDKSKGDPGLKQLAANMSLHFRNELQSIQGYAPIPTPRALEAQDRHQHLLRKGAESKTAASSDKTTNARLTTKAAAKAREQHPAKDEKARVFIRGPSKPETDETVAAVARVMGAAPEELHFKKVNSSWSFMAPKKITTTENMQKVDQAHARIKGLSDFYGVGKDGLEPTKNEQWLNSQIAKQTGGEVKFVRWQFETVKYKDAKLRIAVDLPRGKKLPASMTFEGSDNKCQVVRCRVPSIYHYTVHAAHEEKNHVGPARPCLTCGTEGHAPGDAACAGGARARNPKPSETAVYTSDFKGDEEARSKKRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSQ9</accession>
    <name>A0ABR3YSQ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PAN2-PAN3 deadenylation complex subunit PAN3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">PAB1P-dependent poly(A)-specific ribonuclease</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Poly(A)-nuclease deadenylation complex subunit 3</fullName>
            <shortName evidence="7">PAN deadenylation complex subunit 3</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">PAN3</name>
        <name evidence="11" type="ORF">Cpir12675_005174</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and with PAB1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PAB1 (via PABC domain), conferring substrate specificity of the enzyme complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The N-terminal zinc finger binds to poly(A) RNA.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily. PAN3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000166">
        <property type="protein sequence ID" value="KAL1890984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.5160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03181">
        <property type="entry name" value="PAN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030844">
        <property type="entry name" value="PAN3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041332">
        <property type="entry name" value="Pan3_CK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12272">
        <property type="entry name" value="DEADENYLATION COMPLEX SUBUNIT PAN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12272:SF11">
        <property type="entry name" value="PAN2-PAN3 DEADENYLATION COMPLEX SUBUNIT PAN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18101">
        <property type="entry name" value="Pan3_CK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25586">
        <property type="entry name" value="zf-CCCH_PAN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="10">
        <location>
            <begin position="21"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="8">
        <location>
            <begin position="21"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="114"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Knob domain" evidence="7">
        <location>
            <begin position="629"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="590"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="135"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="368"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="421"/>
            <end position="428"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="485"/>
            <end position="486"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1890984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="730" mass="80329" checksum="72E3852AE2054C3B" modified="2025-10-08" version="1">MSARGSQPAELRRQLGSPNAKSRDTPCKNVLIYGHCRYENQGCTFNHETKTSKTNTSTNPATITPSHASIVHSNTANSTAANNNASLMNAAPPNMAMNSVLASPISHQKTLKWDTPAFTPSSSSTSPSGLHAVPTAPPAISPPAISPNPASTSPLAKKSTFSSQSLYAASFTPRGGNTAPSTPQSDAKKTMAFNPANAKEFMPSNYDLGSGNNESVNQMDSSFSYDVFNMAQVANGIPASTPFNPYVQDHAMAGAGYYPHAGPFMSHAQPLQHHLYANMGPYREDLLPYQKLAHDLFLPEKLREDMLKKLESTLRVIPMTSPQLPEIEDYHSLVALDTSPRSNLSLFGYSTWVYKATSIKDDKTYCLRRLEGFRLTNDAAYKHVLRTSTDWKAVRNSSVVSIHQAFTTRKFGGSSLVVVQDFYPGSKTLEEVCQAASDSRVQGRAHMRPKAVFSENIIWSYIVQLGNALRAIHSAKLAVRCFDLSKILVTDKNRIRLNACGIQDLVQMDERPSVSLQQEEDFIQLGKLILTISLGGTASPNFDGQFDAYFNDLKELGYSMDLRNIILWLLTPASPDIRKSIDDFLPRIVGHAFDTADSSLHAQDYLTSALYGELENARLVRLLAKLGAVNERPEFDGDPRWSESGQCYALKLYRDYLFHAVDANGKPSLDLGRITASLNRLDVGTNDMISLTSRDEQTVFYTTYKDLKRLVESSFQTLVKASAGSNSKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT06</accession>
    <name>A0ABR3YT06_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UBX domain-containing protein 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ucp10</name>
        <name evidence="5" type="ORF">Cpir12675_005175</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000166">
        <property type="protein sequence ID" value="KAL1890985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14273">
        <property type="entry name" value="UBA_TAP-C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01767">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006577">
        <property type="entry name" value="UAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050730">
        <property type="entry name" value="UBX_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322:SF1">
        <property type="entry name" value="FAS-ASSOCIATED FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322">
        <property type="entry name" value="FAS-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14555">
        <property type="entry name" value="UBA_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00594">
        <property type="entry name" value="UAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UAS" evidence="4">
        <location>
            <begin position="178"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="UBX" evidence="3">
        <location>
            <begin position="396"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="338"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="338"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1890985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="503" mass="56058" checksum="A57B53E8D2D62A8F" modified="2025-10-08" version="1">MASGAGRDLAALSADQQEALSQYMAVTNQDFGDAVPLLERSQWNVQIAISKFFDGEGPDPIAEAMAAQAAAPSVHTENLQDSFDMPSPTHRPQTEAAPRVVPQRAGHMPFFFSVLLYPFNFGYKMVSFLYRTVLFIASFLPASIRPRAVTDSLAAGIRSVSGRRMLLPRDTAARFKREFEEEYGQELPFYEGGAAQALDAAKNDLKFLLMVLISPEHDDTDSFVRETLLSPEVVELIKNPANNILLWGGNVLDSEAYQVSLEYNCTKFPFTVLVCLTPKEGSTRMGIIKRMAGPMPASRYLRELSLGIEKYTADLASVRSERRAREAARSIREEQDSAYERSLARDRERARQRREAERQKAEAEQQAALEAQKAAEQKIKGDLWRRWRAGTIAPEPESSNADIVRLAIKMPEESGAGRIVRCFKASATLDDLYAFVECFDLLGSTAHGDWSALDDPENPQDYTHKYEFQIASTMPRVVYEANKEKTLGEAIGRSASLVVESCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUH4</accession>
    <name>A0ABR3YUH4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Golgi pH regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_004777</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000143">
        <property type="protein sequence ID" value="KAL1891918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025969">
        <property type="entry name" value="ABA_GPCR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022535">
        <property type="entry name" value="Golgi_pH-regulator_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015672">
        <property type="entry name" value="GPHR/GTG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15948">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR 89-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15948:SF0">
        <property type="entry name" value="GOLGI PH REGULATOR A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12430">
        <property type="entry name" value="ABA_GPCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12537">
        <property type="entry name" value="GPHR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="230"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="370"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="479"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="531"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="domain" description="Golgi pH regulator conserved" evidence="7">
        <location>
            <begin position="225"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Abscisic acid G-protein coupled receptor-like" evidence="6">
        <location>
            <begin position="366"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1891918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="569" mass="60904" checksum="E31645AB56D9C1D1" modified="2025-10-08" version="1">MFFGIFSSCDRDACSASPASLSLSSLAPIFAIFAAFFIIAYARLLPLLESRVLPALSSATIDGDDHILPSHAPAGLRAIHADHAKRSAVKRGSTVAFSLIVALAAEVALLVVCEVADVFPQNARASAMGVAVPVLVFLLVVVAPALHLRSFVVAMLGRSFSSATGQSRKRTWIVFSVLMGAWLFAFYSVGAVVPPAEPTTTRNGWLNAQSNSSTTQKTRDGLVLASLARIGVIGVALTALLSGFAAVSAPWTTFFSSITSPFRRNRAGNVSETAVARKQGALDATSELLATKRHRISVLETRVSSSDDSCSSPSLVGKVFGTFRGPSNEEAEIRSLRAEISGLETMAQSLASQLSTLLSKRAAALRARTFLGRILAVPDYLFAVYCVYRIVNTSLTASRRFFESHAAAEAHFVSDPISRALGLVALHWDSSIDTASWARQFSFLMSGGILLLSANSALKTAHILSRWAPRAVLAHARSNLPLLLAQILAVYIISAAMMLRSSLPQEARGAVSDALGGGVLQLSFVDRWFETWFLLAGIATAFCIWVSGKLETEDEDEYEAEEKGMVKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUJ4</accession>
    <name>A0ABR3YUJ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_004934</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000152">
        <property type="protein sequence ID" value="KAL1891562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF30">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G13600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="252"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="279"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="149"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="303"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="364"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="17"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="89"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="162"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="213"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="325"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="371"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="532" mass="57321" checksum="58893561AFB21768" modified="2025-10-08" version="1">MNAKDQAVDTKDAGPAVSSSLSSSSLSLVSRINNNRNTSNNINDSIDTSTSDDNKNSSSTGNSGHQQKQFHGILSQSQLPSHHHNLYHTSSTPSSSTTSNTASNTTTAAAATNYHLPLRLHAPLLHYKSSPHLSGFVSASAYTSTTFCQQSTTPLPLPPSFPSSGQQSPVFSGGSFPYKDAPSASASSAMDSFHRQSRHNSHSGPPFAPSGPPSSFTSSPKTSNPSDIGAQEVKLTPVTGRVSRAKRGIPVHYCQECNKTFTRAEHLRRHGLSHGRPEFSCPFPGCSREFHRKDLLERHRQKHRNDFETGDPAVAYPYHSPSHFSPANPGSSGSAPSRCPSAGSLTGLGSSPGAVFYQSQNLSVPGAAPNQQQQQQQQQQQQHQPAHPQHPQHPQHPQHPQHTAIHSAAEFPWGRTRSSSMNHAISSTAQNVNVFYPQFPVTGQYPEFHGMEGSNSGSSHAPSQTTGQVGGSGMDVNIPSGHINIVSSQMHTPEPMYSHSYDASFSMPLDFESLDFFHPYGGQQQQQNDSQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUU9</accession>
    <name>A0ABR3YUU9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_005117</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000163">
        <property type="protein sequence ID" value="KAL1891109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018866">
        <property type="entry name" value="Znf-4CXXC_R1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10497">
        <property type="entry name" value="zf-4CXXC_R1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="JmjC" evidence="6">
        <location>
            <begin position="96"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="623"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="820"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="869"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="961"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1065"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="627"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="915"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="966"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="991"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1015"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1076"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="1130"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1210"/>
            <end position="1219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1891109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1228" mass="137679" checksum="1171A7A6EC8811AF" modified="2025-10-08" version="1">MGSVKTCVLILNIEITGENARDITKQIDIPMTMGHYLRAMRKLANQWTPLNFRDERRQRLYLKDIDCPPEWEQVLRKVIPPNLFYMNENVADRGTQSSRQGGPIRTANSSLVTTGDLMSSLPPQMRAENLMCYIGHEGTYTPAHREMCASLGQNIMVEASKDTEDGELEGSSIWFMTETKDREVVREYFLSMLGHDIEIEKHFAQINAWKKATFPVYVVEQKPGDFILIPPLAPHQVWNRGTRTMKVAWNRTTVETLELALYEALPKARLVCRDEQYKNKSIVYYTLQKYYQKMTHMDPQDNMVDEPLASGVSLRQRTLESDFRRLFLLFADILGDEMFGFKETNVEYIEFDSNITCSYCRANIFNRFLTCKNCIRILADGDEDTYDICMECYAMGRSCFCISNLQWCEQWKWNDLVTNYEKWRAMVIGNDGFVDLERSPLPLELVSKRKKKKTLAQVCQEGLLHRPFKNILNARKLHEDESEPEAEVDSNGKIKKLERRNTRIRASKGHDTKRCHVCGHPDFLYKMQTCSTPGCNEAYCYGTLYRGFDQMPQDVQQMENWQCPKCLGICNCGYCRRAGAVNYYLPKRTLLGHDTRPIADDRSVESLVDFRMHNLSWLKRTGEDARSNTSKRMQQLRAQAEQAKSKSRSVQEAAEGVLSQGAPEGVSTSPTTRDDLALAKDIDAALAVADVTYADAFMTEKSDTAMYPDLDSDNISMVSENRPGFHELPGMGYYQQDDGDDRILFDPYKVPSKESLQLDDPEVSEFVRKSIQAAKRRSRHKSDDDTEFALHPRLAKKPKKDVVRASINLERVVDPALLESGPASPCQPSPTTPIASSPGAIRHNPTNPTVIIYTVTAVEGYQDNAISSSLQKSSSRLQSRHQATSVDAKKPRAGFAMDSNPPTLMANKARKIQKQKKEKEQQDKDIEMTETEVESIAHDHTWKSVATRSTRPAATDILAKPKATLSEHNGSTNNGLGLNDSQYTKRKLNHSLKSVSDSASTSTLAPHKLSPPCHSPDRARTASKSSEEKSSKAHDGSEQPISTAAHQLLSMAERMKMRGRAFRIGQRGGTNSSANSRDEHKNAQLEEEHPHKAAEGPSNGKIVAFDSSSSSTTTTEEPAEGRGRGRGRAGGRGNGRVVGHGAGSTDRPPTHETVFRTRASMNGSKESEQKGSLGVGHRKTSPASDTSDDNDEISQKAPPKNPFAAWRGGTTASARQGSRTWKARSGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVU2</accession>
    <name>A0ABR3YVU2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OBG-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004643</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000136">
        <property type="protein sequence ID" value="KAL1892175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01899">
        <property type="entry name" value="Ygr210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013646">
        <property type="entry name" value="YGR210-like_G4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305">
        <property type="entry name" value="OBG GTPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305:SF1">
        <property type="entry name" value="OBG-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08438">
        <property type="entry name" value="YGR210-like_G4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="2">
        <location>
            <begin position="5"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="419" mass="45491" checksum="A502BC82DDBDEE2D" modified="2025-10-08" version="1">MARDPLIGLVGKPSAGKSTTLNSLTDASSKVGNFPFTTIDPQRAIGYLQIECACARFNLQEKCKPNYGSCDNGRRSVPIELLDVAGLVPGAHQGRGLGNKFLDDLRHADALIHVVDVSGTVDAEGKETRGYDPSVDIAWLRSEIVAWVKGNLMERWPSIRRRHMATKSSAVDTLRAQFGGYGANLKLVQRALDRSGVKEALEEWDDNTVDVIVNSFIDEKFPTVIALNKIDHADADKNIAKIAKQQDPNTLVLCSAVSEVFLRKMVKQGYIKYTEGSEFVDTREDLIADGDELGGGLKELDDKNKVRIENLKDMVLYRFGSTGVVRVLQKAAEVLGLVPVFPVRSISTFGSAGVGDTKAVFRDCVLIKKNSTVADVARKVMGDAPIAFVEGLGGLRVSEDDAVAPGKNDILSFKVGRGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWG1</accession>
    <name>A0ABR3YWG1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Iso-1-cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">CYC1</name>
        <name evidence="13" type="ORF">Cpir12675_004417</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="11">Binds 1 heme group per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the cytochrome c family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000124">
        <property type="protein sequence ID" value="KAL1892718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="entry name" value="Cytochrome c-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002327">
        <property type="entry name" value="Cyt_c_1A/1B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11961">
        <property type="entry name" value="CYTOCHROME C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00604">
        <property type="entry name" value="CYTCHRMECIAB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="Cytochrome c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4 9 11" id="KW-0349">Heme</keyword>
    <keyword evidence="8 9 11" id="KW-0408">Iron</keyword>
    <keyword evidence="6 9 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrome c" evidence="12">
        <location>
            <begin position="6"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1892718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="108" mass="11731" checksum="F1AE27A3CC96A094" modified="2025-10-08" version="1">MAKAEGDIKKGANLFKTRCAQCHTTDAKGGNKIGPALHGLFGRQTGSVAGYAYTDANKQAGVTWEEKSLFDYLENPKKYIPGTKMAFGGLKKAKDRNDLIAFLKKECS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX05</accession>
    <name>A0ABR3YX05_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">Elongation factor 1-alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TEF1</name>
        <name evidence="10" type="ORF">Cpir12675_004629</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000135">
        <property type="protein sequence ID" value="KAL1892273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01883">
        <property type="entry name" value="EF1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03693">
        <property type="entry name" value="EF1_alpha_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03705">
        <property type="entry name" value="EF1_alpha_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_A">
        <property type="entry name" value="EF_Tu_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054696">
        <property type="entry name" value="GTP-eEF1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004539">
        <property type="entry name" value="Transl_elong_EF1A_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00483">
        <property type="entry name" value="EF-1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008969">
        <property type="entry name" value="PRK12317.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22594">
        <property type="entry name" value="GTP-eEF1A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 10" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0488">Methylation</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="6"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1892273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="475" mass="51350" checksum="B30EA353577F5A90" modified="2025-10-08" version="1">MGKEDKPHINIVVIGHVDSGKSTTTGHLIYQCGGIDKRTIEKFENKSPLFTLIVVDSMQLEAAELGKGSFKYAWVLDKLKAERERGITIDIALWKFETPKYYVTVIDAPGHRDFIKNMITGTSQADCAILIIAAGTGEFEAGISKDGQTREHALLAFTLGVKQLIVAINKMDTAKWSEARFNEIIKETSTFIKKVGYNPKTVAFVPISGFNGDNMLSSSTNCPWYKGWVKEVKGGTSTGKTLLEAIDAIETPKRPTDKPLRLPLQDVYKIGGIGTVPVGRIETGVLKPGMVVTFAPSNVTTEVKSVEMHHEQLTEGLPGDNVGFNIKNVSVKDIRRGNVAGDSKNDPPQGCASFTAQVIVLGHPGQIGAGYAPVLDCHTAHIACKFSELLEKIDRRTGKSVETSPKFVKSGDACIVKMIPSKPMCVEAFTDYPPLGRFAVRDMRQTVAVGVIKAVDKSAASGGKVTKSAAKAAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXI5</accession>
    <name>A0ABR3YXI5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Small nuclear ribonucleoprotein Sm D2</fullName>
            <shortName evidence="9">Sm-D2</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">snRNP core protein D2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SMD2</name>
        <name evidence="11" type="ORF">Cpir12675_004290</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the snRNP core protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000118">
        <property type="protein sequence ID" value="KAL1893056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01720">
        <property type="entry name" value="Sm_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027248">
        <property type="entry name" value="Sm_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12777">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="36"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1893056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="111" mass="12727" checksum="3B4600CBA45B5AA3" modified="2025-10-08" version="1">MADTKIQELLTKPRSELTEYEIAQLEEHEFSAGPLSILQTAVRSHTQVLISIRNNRKLLARVKAFDRHCNMVLENVKEMWTETPRLANGKKGRPVNKDRFISKMYVGCVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXJ8</accession>
    <name>A0ABR3YXJ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000116">
        <property type="protein sequence ID" value="KAL1893109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="380"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="405" mass="45390" checksum="6871B7E309CF1DC8" modified="2025-10-08" version="1">MAHLTRRIPVTHSGAKDGWEEVDQVGFDPSKVYRSPIDLKVAASVRLYSHKFTWREAETTSGFSDAFLGSRIWSLSETIRVFAETVVQGNPEVPGYEVPQEYRWGIPYNRNFVLGKSAAYFTKAIRFTGGFDQVCEVLRSPATVALVIRSMVMQVIIEKVFRVSFFGFAVDESSIGNSERQHHAFAQRIVNGSDSAPSFCTACKIVALEILEVITPLLDIAAQHWPRRGPALSLIIQALFNQVSEAGLISVALRSSPSKIIFSMPTPGEPYHFRRHVERTPNSINIRGFTQKLSSTASKGINNNVILAVFVPLQPFVQRAPDNPFTLEGIIAHGDVVTYETASWENGRQKTAPSSIFLRPHAFLWSLCTSLVFRKIMLTIINLLMAFFFFGLAFKIFWPAHFLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZB8</accession>
    <name>A0ABR3YZB8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin-like protein AAED1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_004195</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000113">
        <property type="protein sequence ID" value="KAL1893262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02970">
        <property type="entry name" value="PRX_like2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032801">
        <property type="entry name" value="PXL2A/B/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28630:SF3">
        <property type="entry name" value="PEROXIREDOXIN-LIKE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13911">
        <property type="entry name" value="AhpC-TSA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1893262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="229" mass="25562" checksum="0E88FD2A39CC7EEC" modified="2025-10-08" version="1">MTDTLDKPINDPAGADSLKPRDFEGYVVTNDNLPTKNTIQKIGSFLLLDREGSAHTFEKVVNVAERTFVIFVRHFFCGNCQEYLRALSAAIRPSSLPQDTAIVVIGCGDPRLIDMYIDATGCKFPLYTDPERKIFDALGMIKTLQLGDKPWYMEKPLAVSIVASICQALRYLPKGLALSSGNHWQVGGEFMFETMDGTRRVTWCHRMRSTRDHAQLSAIEKVLKIGSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZU7</accession>
    <name>A0ABR3YZU7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Vacuolar protein sorting-associated protein 55</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">VPS55</name>
        <name evidence="7" type="ORF">Cpir12675_004110</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OB-RGRP/VPS55 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000109">
        <property type="protein sequence ID" value="KAL1893457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007262">
        <property type="entry name" value="Vps55/LEPROT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12050">
        <property type="entry name" value="LEPTIN RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12050:SF0">
        <property type="entry name" value="RH04491P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04133">
        <property type="entry name" value="Vps55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1893457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="129" mass="13892" checksum="DEBB2E3B745FEE96" modified="2025-10-08" version="1">MSMAGIKTIIALSFVLALGFLLVILSCALFKEYYPLLVVATYVVAPLPNWICGQCASRDAFADNEASAVPDVGRFLTGFLVVMGVVFPMILAHAALIQVEAMIMSIVGGLLIYGTIISFGMFFAEEQDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZZ5</accession>
    <name>A0ABR3YZZ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PQ-loop repeat-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_004138</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000111">
        <property type="protein sequence ID" value="KAL1893400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052241">
        <property type="entry name" value="SLC66/Scramblase_ANY1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14856:SF9">
        <property type="entry name" value="PQ-LOOP REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14856">
        <property type="entry name" value="PQ-LOOP REPEAT-CONTAINING PROTEIN 1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1893400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="258" mass="28573" checksum="FFB63B7890CE8296" modified="2025-10-08" version="1">MTFITTLSAWLTPIFIVMSPILSYSDQALSMHRNKSSAGFSLDIPLIMLSASVLKCFYWLGSHFDISLLLQAILMIIMQVILLKIALDNRPTSKAETAVPFAGVQEKGLLSGPRPYEFWQWRSSKPYWSFLLYFSGALAVLHILLSATPVYPSYSDMLGVVGLGIEAILPLPQIMANTEARSCKGFRLSVLANWLVGDAMKLFWFFTASSTIPLTFKLCGIFQSCCDAFLGVQYCFYGDGEAQGDFALQPVATVEKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0D5</accession>
    <name>A0ABR3Z0D5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">26S proteasome non-ATPase regulatory subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPN3</name>
        <name evidence="5" type="ORF">Cpir12675_004063</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000107">
        <property type="protein sequence ID" value="KAL1893632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050756">
        <property type="entry name" value="CSN3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013586">
        <property type="entry name" value="PSMD3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057985">
        <property type="entry name" value="TPR_PSMD3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10758:SF2">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10758">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08375">
        <property type="entry name" value="Rpn3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25573">
        <property type="entry name" value="TPR_PSMD3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="4">
        <location>
            <begin position="294"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="518"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="518"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="535"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="548" mass="60952" checksum="C84835C7469563BF" modified="2025-10-08" version="1">MPTDTRKTKKDKDGDEKMTVIVPPSKKLNKKADADVDMTDAATDVVEPTVDPVAQAISDIKANCALLDRGVTLFDARFSLRALRSISLLRKRLTPDVIATAVVETYSASSASISIAKGILATIGREEMSFVSTPADIDVDSEPKKSSSVAKKEKEAKEVFPEVGVYLSILVQVFLLDHKELDKGAKFSMELAEHIHSLNRRTLDSLAAKVYYYLSLFVEQLSPKPPSPQSPIVSIRPILLAGLRTAVLRSDTDTQAAVIVLLLRNYLLTSSIEQADLLVSHTQFPENASNNQVARFLYYLGRIRATQLRYTEAHEHLTAASRKAPSSACAVGFTQSATKMLIVVELLMGDIPERATFRQPALETSLQPYFQLVQAVRVGNLDLFEKAIASEASTFRKDNTYSLVLRLRQNVIKTGIRMMSLSYSRIPLRDICIRLQLGSEESAEYIVAKAIRDGVIEATLDREHGFMKSKDVGDVYATREPADAFHDRIRACLALHDESVKAMRFPMNQHRLELKNAQEAREREREMADDIQNGDLDDEDMSGDFDGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0H0</accession>
    <name>A0ABR3Z0H0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000095">
        <property type="protein sequence ID" value="KAL1894129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021047">
        <property type="entry name" value="Mannosyltransferase_CMT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34144">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34144:SF7">
        <property type="entry name" value="EXPORT PROTEIN (CAP59), PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05020)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11735">
        <property type="entry name" value="CAP59_mtransfer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="448" mass="50935" checksum="F284A87CDA9BB578" modified="2025-10-08" version="1">MVRNSVVPPNKRHTSPPPLLPFDMANGSYQPQSSYTVRSFRMRLRRVMRTPWPRVFICLFSLLQVLDIVNIHLHLAVVHDSSDIMELSHRHQGERIYIASMHWNDGPLVRNHWSNAVLQLADVLGPNNVYVSVYESGSWDDTKDALGELDAKLGRLGVARSITRSHVTHRDEIEAAPVGDGWINTPRNKRELRRIPFLAKLRNRTLRDLEALHKQGVHFDKILFLNDVVFTAEDALRLLDTNEGAFAAACSIDFSKPPQYYDTFALRDSDGKAHLMPTWPYFQSAASRNAMLLNEAAVPVKSCWNGIVAMAAAPFLDASKPLRFRGIPDSLAIQHLEGSECCLIHADNPMSKEMGVFLNPQVRVAYNYEAYQATHPPNGESWLTWGQIAKGLWESRIRRLFTFTFTKDWVVSSRIRSWKSQSPRNSEPGDFCLINEMQVLVENGWAHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0S9</accession>
    <name>A0ABR3Z0S9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Choline transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_004017</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000105">
        <property type="protein sequence ID" value="KAL1893670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF20">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1893670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="342" mass="37158" checksum="25C26585390D7578" modified="2025-10-08" version="1">MTDSELTQVASKELGVKASLESQTADADVMRLAQMGHQQELKRHFGILSLIGLASTTTNSWTGLGLALITEIGAGGPGAVIYGFILVTILQCFPGASLAEFVSSYPTSGWFSVSGWIFTTASTNIMYAQLLMALRLRHQDLAYLPGIPGPQHSHFECRHVWEPHRDERFAFRTWINNTGWESNVICFITGLVNPLYSLGGLNGITHITGEMPNPSRNAPLAIAITLCIAFVTGLTYLISLMFCIQDFDALTTTNTGIPLTELFHQATESVGGAFGLTFILFIALGPCMVSSQLSTSRVVWVFARDKALPFSSAISKVSKRFEVPINAQFPVSTIVALLVYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0Z0</accession>
    <name>A0ABR3Z0Z0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Phosphate metabolism transcription protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">VTC2</name>
        <name evidence="9" type="ORF">Cpir12675_003722</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000093">
        <property type="protein sequence ID" value="KAL1894294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14480">
        <property type="entry name" value="SPX_VTC2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.100.30">
        <property type="entry name" value="VTC, catalytic tunnel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051572">
        <property type="entry name" value="VTC_Complex_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018966">
        <property type="entry name" value="VTC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042267">
        <property type="entry name" value="VTC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140:SF2">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE 3 COMPLEX SUBUNIT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09359">
        <property type="entry name" value="VTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="649"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="675"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="713"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="8">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="560"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="566"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="759" mass="86534" checksum="D2186CA70F510747" modified="2025-10-08" version="1">MRFGKTLQEAQHGPWKDMYIDYAKLKSLLREDKYDDDEVPWTETDENKFCDEIFNNQLEKVAKFQEDTFNNLKDRVEVTYNKLKGLATEGEGEGENDGPSVSMSKEYAKQVEFELDDLTEELRQLKKYSSINYTGFLKIVKKHDRKRGDHYKVRPMMQLSLSKRPFNSEKSYTPLINKLSVMYYIVRQHSERGEGSNFHPELDIGVQEDGKHTAHKFWVHPDNLLEVKTYILRRLPALVYAEQAASVDDASNDPTITSLYFDGPKFSLYSKKVERNAKASSLRLRWYGDLNSVPELKMEEKTVHASGSAEEHKFDIKQKWIKPYLGGQYKMERSIAKMERQGQKATEIDTFKANTSRIQESILSQKLAPMLRATYVRTAFQQLSDDRVRISIDTDVAFIREDTLDLSRPCRDPASWHRTDIDNSNMKYPFSNINQSEVSKFPYAILEIKLQEGRKRPEWVEDLMGSHLVYPAPGFSKFVHGVASLFEDYVNALPFWISELEGDIRKDPKEAFDEEVQRRIQKAEDEQIVGSLLGAKVGSSFKPTTSSPVAEGILTQRAQAEMSGVRPSNLSPSSRTNTEDEVPTRTGISSVLPSFSMSRYAQNRRAKQSANSQELPEGVVEPEVWIKNSGELKIEPKVWLANERTFLKWQHISILLGGLAVALYSAAGKDTVAEIMGITYIIIAIFAGGWGYAMLNVRRRMIHERSGRDFDNVVGPLIIAVAMAGALVINFFLEFRKAFYSVQTPHNGTSSSSYLGNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z114</accession>
    <name>A0ABR3Z114_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Xylose isomerase-like TIM barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003998</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000104">
        <property type="protein sequence ID" value="KAL1893698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050312">
        <property type="entry name" value="IolE/XylAMocC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12110">
        <property type="entry name" value="HYDROXYPYRUVATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12110:SF21">
        <property type="entry name" value="XYLOSE ISOMERASE-LIKE TIM BARREL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="Xylose isomerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylose isomerase-like TIM barrel" evidence="1">
        <location>
            <begin position="26"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="423" mass="46291" checksum="9DEA87FC56C9D154" modified="2025-10-08" version="1">MPSQLGISTMSLGRCWAGHSFEHKMDMAAKYGYAGIELWHEDLMDIADRYPNGGAASLENQKTAARYVRSLCDARNLTILCLQPFALLEGAIDPAVHPARLQELEHWMELTRQLGTDLIHVASSMAPASELSADLELAVTHLRAAGELALRQNPPVRLSYESLAWGSRVDKWEQSWDIVKAVDLPNFGLCLDTFNIAGRIFADPSRANGCTEDAQKAVDASMKRLVASVDVSRVFFVQVVDAALLAEPLLPGHKYYDPAQPCRMSWSRNCRLFYGETERGAYLPVKQISAAIFKGLGFEGWVSLELFNKRMSETDKGVPEELARRGAESWDRLVADMDLTVASKPAKAVFPATMATATPITTAIAAAPAVFTITAAKPVRLLPRAQKNKAAHVVDGSLLRKALPASVYVLASSMCLYLGMILV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z294</accession>
    <name>A0ABR3Z294_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycoprotease family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003708</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000092">
        <property type="protein sequence ID" value="KAL1894326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="759"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="450"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="787"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="947"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="484"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="947"/>
            <end position="963"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1164" mass="128159" checksum="9CC380F7F30D4DFD" modified="2025-10-08" version="1">MNSSPDYRPTPYRYEEHLAPRPQSQVQDSWDEWEDEDVYTPIDDNVQLVPRVSELYAGNSEPPGRQNPDKNPVKQSINRLSKASINRFSRLKSRKRQKFQNEQAGIKLITDMESLRKGQDRREGYHVDGASSMGFVDAAALRAIASSSAQEDGNQIPHIAPRDSQSSADTIEIHIEMSHQDLYGTKKGAKSIMGDSLVGVSSQNTPEVSPYPPIYHPSQQSATMYLSPSQQKSVWSPDTPDTMTTFDHTPASATSVFSISQNNRGSDTQEATRETEHTVSAGQTQFHMPFKNLAERTSCYPISIFDRYGPDSPYIHIDDNPVPAMTSSANDHVQNLEEEKVKPVKPHLTVENPGDFQGFFHDKNEATYWLDHLSESPVPKQQSVPTAFPAEVRNSHVQDMPLIPVIHNQPLSRAVSHKAVPEIMVTPTYETIDTTEFNWWKEGGTSEKQLLDQEQLQSQEQRHLPQSSQEYDPYAAREPATTRLASSNSSLASSNKVLRVNTSSRMPLASATMASSDRPLVSREVNTANTANTSNIANKLNTVNTVNTANTAKTVSTANTSNTIAATNTTNTSNTINTENTINTKVNTNAMATTATTNIVNFNTSYTFQNGSIVDEKFPLTHSPPAMRKQARYQAVFPPGHPMEQRRPQSPGIISPGFAGGLSPRGGVTMTEIPLTPATGDHRSTPFGRGGVFHAGPDAAAIHIHKKKKWESERRRQRYEKEDRVSRKLGNFWRGRGCIPAKGCFGRNGREGRFRRRMWLLLILVLIMLIAGSLLAGLLINREKTPFFEQPGSQPEPHPEPEPQPQPQSIWVNVTNFPPMPTGVLTVVGPNNDISYDGCTEPSTLWSCSLPKEQQNEVLPFRGTQPTVTLNIQYDNNTNESWRTSWDNSTDASAVVSSFSPAPQPPSTEEMAFLGTYTDDVKAGDKAGEPTPFYISMLDMNDNATRIGSSENSGTVVNPTRNISLPLPESKSDGSTATARLFPRLWQQPVRLFDRGLSTEHYGFYAYFRRTIYVQSLEVINSTTGSGTDDTVDGNGGALITDANYLITWGQTRVKVALWTSLGNSSSLLAATSGTESEGSANRPGTLPYPATIRLDTHGGNPNDKLVWAWAVSNSKVDTSKTYFIANDIGKDGLVDNPRGDGDAALGGFDGGVGGCRCQWQNFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2C9</accession>
    <name>A0ABR3Z2C9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">RIM15</name>
        <name evidence="15" type="ORF">Cpir12675_003527</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 17">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 17">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000085">
        <property type="protein sequence ID" value="KAL1894786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05611">
        <property type="entry name" value="STKc_Rim15_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE GREATWALL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="13">
        <location>
            <begin position="41"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="744"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="14">
        <location>
            <begin position="1188"/>
            <end position="1308"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="12">
        <location>
            <begin position="1549"/>
            <end position="1663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="128"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="328"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="390"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="626"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="902"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1040"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1264"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1318"/>
            <end position="1487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1670"/>
            <end position="1736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1762"/>
            <end position="1787"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1805"/>
            <end position="1941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="145"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="338"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="394"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="640"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="691"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="718"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="920"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="938"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="968"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1047"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1275"/>
            <end position="1286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1319"/>
            <end position="1330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1363"/>
            <end position="1388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1402"/>
            <end position="1421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1467"/>
            <end position="1485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1706"/>
            <end position="1715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1722"/>
            <end position="1736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1775"/>
            <end position="1787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1805"/>
            <end position="1814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1867"/>
            <end position="1880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1894"/>
            <end position="1907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1909"/>
            <end position="1929"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1894786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1941" mass="211517" checksum="2C795D260513022A" modified="2025-10-08" version="1">MALEPKSAAPLGLSPLVSPLSSLRAEAVNMQRSFSQDIREEREELREAAEQSLNVIVDVNLDGTIRWAGPSWTELIGSDGTEVIGKPFSDLIVSDNKNVFIEAIELMKKDDSKSFGVHFAINLGPQSRLIRTPPTPTIQTTFASEEGDNDDNENDETTEGKQSQTKTAIFEQEEATPVIDLEAQGIIVYDSASGGESHTMWMIRPWKAPREIKIDIPAVIVQSLGSGAEVLATYLALLAESGSPDPESHPPPPPPLLCRICERSIPAWWFEKHTDLCLQEHRAELEVQMAQEALSEHRHAIVKVLDALEARKSRTMSIEHSTTMAEYKGLPIGPPPSTHSSPGGSSTSSRERSAFGHTRGRSFAVRRPQARIVELLVDLCDTSLEISTPAVKEPSQNQDPLEFRTQSPQSESRISQVLHWQSPSTNTLEQEQGLALLCADTERSAKEKVDAVLRHRKIIEYAERIRIEFAVLVQDCIDDAIQKSARLAAGCLSDSDGGTDPADASTINGEYFAQESSFDPPSALVAALQKASEDTDANSRPISFVESVSLLDSPRECPTPVLNMGGTSMSGPILRESRRASRRESMIFGSEAGDSDISVRSSSIASRMPLRTDSPISEFGDLRRAANVKHHQRRSLVLPGSTSPHRQESPSRFPNHQPTSPLRIKPRSYPYTHEGVGSPEASPMLPGSDFSSPAPMSVHSSSHHRRQSSAAMSEFVMKPPPSPRLGAHNPPPQARPSQPSIKDFEIIKPISKGAFGSVYLAKKRTTGEYFAIKVLKKADMVAKNQVGNVKAERAIMMWQGQSEFVAKLYWTFSSKDYLYLVMEYLNGGDCASLIKILGGLPEDWGKKYLAEVVLGVDHLHSRDIIHRDLKPDNLLIDQKGHLKLTDFGLSRMGLVGRQKRAINSDGAEPAPDLLKHGPFARSSSMASSRSTSLDMQGPNGTQSPCMTPLTTPDTGSILGLPSALSLGPASTSHPEPKRTSTYRSESGNSESLSQMLNRLSFNEGNSSIISAGSKSIEDSSDTSFTDVPMSPNLSLHYTASHADSDSIKPSSTSTTQSTAMLPPAMALFDPEDNSNRRFVGTPDYLAPETVRGEKQNETSDWWSVGCIMFEFLYGYPPFHAPEPALVFENILARRIEWPDESEEEITSPEAKDLINKLLCMNPDDRLGANKDDKFPSGGYEIRSHPWFSDINFDTLLEDEAQFVPHVEDPENTEYFDSRGATLQSFQEEIEDNNSGPSTNPGADYHERPHDALARVKNCSNPPIKRGMIPLSIPPHIRDSKSRRLSEPVDTDDFGNFSFKNLPALDKANKAMIQKLRAETAQNKPSLNTGINAMPSPGPSVENSPVVPASIQRTLSNAKASARPRSPSTFSHSNSPSRISQPSSPLLLSFVASQNNEGRRKASGTSSGLSQQSSISQTSQPSETVKPVSVMTKSASALAATPVKPRSSALPPLSVSPQKGLMTPRPGSATTTRSRSLTVGSQSNDGSPIMTDALAHHRNRRSQVFDMSPSSSDTEGDKHNAFLNVQRRRQNSRRFSQIALDGGPLFRPLDVLIGEDHPVSRMVMEKLLEKLRCRTILVSTGADAVRYATSDIKFDIIFLEFKLPQINGTDVARMIRETKNANAHTPIVAITAYLKELQAPHYFDSLIEKPISSSKLSEVMRNLCHWKPASSHQSVPVSLPHPAPPSTRLASLRSEGSSAPNGPTGLSGRTTSSLVPSSREDSVSSAYGDSESVTTDDLSFSANNRKALHGDWEDNGLSIRDYDPSDSIASQPRLGSSAGSDTSSSISRVDSNSLFTKKLIIKPHPRRDFVTDKRSSSGTESADDEDEELGALREKHLRPRPALPSSKLGIEMMRASSHDSITLPPEFGTTTTSNPSTLSQVSKPGKASPGPPSDSGPLSQPSSGSVSPMRRVEDTSADKTPRAGKYHDTASEIPTPRPLHKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2X2</accession>
    <name>A0ABR3Z2X2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">BAR adaptor protein Hob1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hob1</name>
        <name evidence="6" type="ORF">Cpir12675_003443</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000081">
        <property type="protein sequence ID" value="KAL1894984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07599">
        <property type="entry name" value="BAR_Rvs167p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046982">
        <property type="entry name" value="BIN3/RVS161-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174:SF1">
        <property type="entry name" value="REDUCED VIABILITY UPON STARVATION PROTEIN 167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00721">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51021">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="BAR" evidence="5">
        <location>
            <begin position="17"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="405"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="280"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="298"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="367"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1894984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="464" mass="52553" checksum="ED8711E99F41D261" modified="2025-10-08" version="1">MSFKGLTKSIQRAPQQFKAKFSIGENTKDPVYTDAERRFAELENETKKLHDESKKYFEAINGMLSHQLEFSKAMTEIYKPISGRMSDPDSLKIEGNPDGIRACEEYESVVRDLQETLKPELEMIETRIIRPANDLLEVIQVIRKTAVKRDHKQLDYDRHRTTLKKLQDKKERTAKDEKNMWKAENDVEQSTQEFNYYNDLLKEELPKLFHLETLFIQPLFQSFYYMQLNVFYTLHERMQQVDIGYFDLTLDIEEAFLLKRGDVQERAEALTIVRFKTTGRPRPPKFAKPALEGRTPGLLTAGPSASSSSPTATPILTSAPPATAKYSLPTSSTSSSIPSSSSSRLPFHKKNDSDSAPPPYSPLKPSTLASSHTTPNLSLTAAAKSKPPPPKPKPSRFSMQPQAAPAVEYVTALFDYAAQAEGDLSFSTGDRIEIVFRSNDTNEWWTGRLNGREGQFPGNYVEIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z430</accession>
    <name>A0ABR3Z430_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peroxisome size and maintenance regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PEX29</name>
        <name evidence="8" type="ORF">Cpir12675_003461</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000082">
        <property type="protein sequence ID" value="KAL1894967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052816">
        <property type="entry name" value="Peroxisomal_Membrane_PEX28-32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010482">
        <property type="entry name" value="TECPR1-like_DysF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28304">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28304:SF2">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06398">
        <property type="entry name" value="Pex24p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="TECPR1-like DysF" evidence="7">
        <location>
            <begin position="134"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1894967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="542" mass="60787" checksum="D703BA114B8E39E8" modified="2025-10-08" version="1">MDEFTADLFVSRDPSPDGEHVPLRVCDKDRYQQQRQDSPHAGGHNDKPSRQKTSPSKSSNIVPVAPAPQPRAQETKGGGFRQRIAALRDKASLQDRLLETILAQIVPEDDSAAASRPPVPQATGMEFYENRPNFNITTMSNNFRRFNARIGVVFKFQEQVIRILTWQRYSHTLSVLAVYSFVCLDPHLLPILPLAVLMLGVFIPGFLARHPAPPRGPGPLTYSPGGPPIAPAHTAKPAKELSRDFLQNMRDLQNCMDDFCVGHDQVVSTIVPITNFSDEAHSSAIFVFMFAASVLMSISAHLLPLRLLFLAGGWAVFGMHHPRIAAQLEATRRTHAESQEALAKRWLDTWIRHDIILDSAPETREVEVFELQRMIAGSSEWEPWLFSPSPYDPLSQPRLAAERPRGTRFFEDVLPPEGWEWSEKKWALDLWSREWVEERIITGVEVETEGERWVYDMPSATSVADAKMDPTGVAPLRSGDDNGSIASSPVALEPLQGVAGDTLQAKAGLDAWDEGEGVVQHGEWRRRRWVRIVKRQQQVEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z526</accession>
    <name>A0ABR3Z526_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mitochondrial K+-H+ exchange-related-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003237</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000073">
        <property type="protein sequence ID" value="KAL1895376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018786">
        <property type="entry name" value="Mit_KHE1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28062">
        <property type="entry name" value="K+-H+ EXCHANGE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28062:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10173">
        <property type="entry name" value="Mit_KHE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="429" mass="48904" checksum="3BCD1CC2AC969A69" modified="2025-10-08" version="1">MNAMRLFVLPVSTKRSLLYAQRFNATTTVTNASLNDRLTRRASAMWTSWETKDGGWQKHLVLYGNKLLRRIPMEEWSLKSVPPLSSQLQKLETEAAKKATEPVEVVYPGAAISKEQVPIVLRKLATERDAMHRRRLIWCCIGMPIAVPFAVVPVIPNIPLFYLMYRAWSHWRALAGGKHVRFLLDNNLLQLRDSSKLDTAYTSQNLCSDGSKATGSCSPSTYDQSSESPERLLLNDASVRKLTTVMNIPEVHAELDRAVYQVQNSTTSESLLRTSKKDEQSKTVGDIAKETNPAKTEVEMDKDSVAQHQQQALDRTLYRDEKTQKRHEDQDPSLVSNTAATHKPSFRSFSVKDAVDESNPAQIPMDKHSVAKHQQDVLEDTLYRDEKRQTQIEEADKAWTNHTKRAAKTKKDQKPWKKANKEKLWKKSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5P5</accession>
    <name>A0ABR3Z5P5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Transmembrane osmosensor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">SHO1</name>
        <name evidence="13" type="ORF">Cpir12675_003000</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Forms homooligomers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SHO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000065">
        <property type="protein sequence ID" value="KAL1895960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11855">
        <property type="entry name" value="SH3_Sho1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035522">
        <property type="entry name" value="Sho1_SH3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="8" id="KW-0346">Stress response</keyword>
    <keyword evidence="6 11 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="12">
        <location>
            <begin position="241"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1895960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="300" mass="32411" checksum="1BE4653ED75BD7BA" modified="2025-10-08" version="1">MEASRAQYSRRGGFNVGNIVGDPFALATLSISMLAWFIVFIASIISQIQTANRVYPPFAWWTTVYLLFVNIGVFVVIASDAIQTYHVAIVGYLSAGLILGSSSVDNLIYSSRGPFQAAAAGFILLCIVQIVWIFYFGSAPSAVTRAYIDSFALAKESTLNHQQNMATYGNTGRPETSTSVQPPQMYTTSAQLNGFETSSPLPGLSAGGRTSVGGFGASINSNINKPTPTGAPDTEVVPPTEYPYRAKAIYSYEANPEDANEITFSKHEILDVSDVSGRWWQARKENGETGIAPSNYLILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z655</accession>
    <name>A0ABR3Z655_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mannose-1-phosphate guanyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">GDP-mannose pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">GTP-mannose-1-phosphate guanylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">MPG1</name>
        <name evidence="15" type="ORF">Cpir12675_003409</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in cell wall synthesis where it is required for glycosylation. Involved in cell cycle progression through cell-size checkpoint.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>alpha-D-mannose 1-phosphate + GTP + H(+) = GDP-alpha-D-mannose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
            <dbReference type="EC" id="2.7.7.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; GDP-alpha-D-mannose from alpha-D-mannose 1-phosphate (GTP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.13" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000080">
        <property type="protein sequence ID" value="KAL1894994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004475">
        <property type="term" value="F:mannose-1-phosphate guanylyltransferase (GTP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05824">
        <property type="entry name" value="LbH_M1P_guanylylT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06425">
        <property type="entry name" value="M1P_guanylylT_B_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056729">
        <property type="entry name" value="GMPPB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045233">
        <property type="entry name" value="GMPPB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050486">
        <property type="entry name" value="Mannose-1P_guanyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22572">
        <property type="entry name" value="SUGAR-1-PHOSPHATE GUANYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25087">
        <property type="entry name" value="GMPPB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleotidyl transferase" evidence="13">
        <location>
            <begin position="2"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Mannose-1-phosphate guanyltransferase C-terminal" evidence="14">
        <location>
            <begin position="256"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF25087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1894994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="364" mass="39976" checksum="B0D942BC413E9CA1" modified="2025-10-08" version="1">MKALILVGGFGTRLRPLTLTLPKPLVEFGNKPMILHQIEALAAAGCTDIVLAVNYRPEVMEKHLAEYSEKFGVNITFSIENEPLDTAGPLKLAESVLSKDNTPFFVLNSDVICDYPFKELADFHKSHGNEGTIVVTKVEEPSKYGVVVHKPNHPTRIERFVEKPQQFVGNRINAGMYILNTSVLSRIELRPTSIEKEVFPAMVRDDQLHSFDLEGYWMDVGQPKDFLTGTCLYLSSLAKRSPKQLAPVSEPYVHGGNVLIDPSAKIGQGCRIGPNVTIGPNVVIGDGVRLQRCVLLSGSKIKDHAWVKSTIVGWNSTVGKWARLENVTVLGDDVTIGDEIYVNGGSVLPHKSIKANVDVPAIIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z678</accession>
    <name>A0ABR3Z678_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA repair protein rhp26</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rhp26</name>
        <name evidence="8" type="ORF">Cpir12675_003275</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000075">
        <property type="protein sequence ID" value="KAL1895318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.850">
        <property type="entry name" value="SWI2/SNF2 ATPases, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050496">
        <property type="entry name" value="SNF2_RAD54_helicase_repair"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629:SF7">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629">
        <property type="entry name" value="SNF2/RAD54 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="420"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="773"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="130"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="234"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1078"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="39"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="130"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="257"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="324"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1204" mass="135689" checksum="108249C4C36F5BAA" modified="2025-10-08" version="1">MSVPQNTAEAQAVSAAINGIVDVHQQDDLQRDVTSEAHAAIFEQDNKRDEERIANLKQKIVKIQANKTTLSAEFDKKSGNFVFRIQAVALRKKIDKCELDVAEALDEIEAFKDRIANRIEQQKTALAAKKLKASAPSQPGQTDTANGESLSRLAESAGPAGPVQQEGEYLEEYLVRTGKITPFDLQNGRDLQEFMEELGSTPDGRATKRHQELLQPGFESQSLKEVVGDTNTLATQEFSLRPRKRRRQLTDDNDDGDNVKDGDLDPKDQPTSKKRTVGTKAKAKSRTKNKTSRNSDSDSDYADNRDDESSTASDDMGGYDDTEQDSKASRAEKALPAKIDLSRIDDGNTAQYRRRLAGWVEKRSGLRESLGLPDPNPEMEEWYKPTPGKEDLKLIDGYSLPSEVGSFLFPFQKVGVEWLCQLHSRLEGGLLCDEMGLGKTVQIIATLVALHYSKKLEGPAIILAPSTLMAQWVQHFHTWWPPLRVSILHSTGSGMLDPEKEEQDTRDSLTPKKLEAARRIIDNVVDNGHVLITTYKGLQTYLDELAVVSWGYVALDEGHLIRNRNTEASKACKQLATYNRIVMSGTPIQNNLRELFSLFEFAYPGLLGTDTRSFSQHFEMPIRDGHHRNATNLAIMTAEKCARTLRETVKPYMLRRVKADVADSLPPKSEQVFFCKLTPQQEDIYVKFIESPHIKALFADGKTLQQKNAVFAAIDTLRKICNHPDLRWGKKHSKLGLDGVESSQVRGLRKYEHGGNREDDSDFGNPERSTKMQVLISLLRISKNFGHKTLVFSQSLPVLDIIEIYLRDEGYAYVRMDGTTNQIERQPMVDRFNQSKELEVFLLTPQTGGVGLNLTGANRVILFDPSWNPATDKQAVERAWRLGQKRPVEIYRLLTPGTIEEKIYRKQLYKQFMTDKIMTETEFHRSFDSNSMADMFTYKAEEKDRDLDIFEGAEAKFQKNGDSRHGEAKNTDGISKLNVGLQDAEPKAEKKKVATVGVLPTEEATVVSHLDQVKAIEEFQPDKTEAEQGMLEDLFTRSIDSAYNHEDIINAKQRVQANRRFLEEEAERLNRETKRFLQQQAARAHHDRHSAPSRSSSGPNMGGVKTRPTVLTKTSAAALAPRRNQPAIEMMWTLRSLKSLISGFLEEQDGQAHTADIANYFNSKYNDLPADLFRRALESVAKMHDAPAAARKKGTKLWKLKRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6L7</accession>
    <name>A0ABR3Z6L7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_003342</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000077">
        <property type="protein sequence ID" value="KAL1895159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026050">
        <property type="entry name" value="C1GALT1/C1GALT1_chp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033:SF40">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033">
        <property type="entry name" value="BETA1,3-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="51"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="536" mass="61070" checksum="8C0EF1A3DF386925" modified="2025-10-08" version="1">MGLSADSLPAMPRTVLLMLSRRRVMVMVVLVIMLMGFTLAPTSLIPSNLAESSAAAPAHQQPQDESHPTHEQNPQTTNIESHNGADHATSAAAASPVATENALIPQNIDQPARRLDPVCDHFPDTSNILIIMKTGATESFSRVPTQLLTVLRCIPEYFIYSDMEQTISGFHVRNALDTVLQEAMDENPDFDLYRRQQQCVIDQDTCNADQSGSHNGASDGWNLDKYKNIHIAEKVWAMRPNYDWYMTIDADTYVMWPTLMQWLKTLDPKRPQYLGNVALLGSFPFGHGGSGYLLSNAAMEEFVGKHPGVANDYDVPVKSVCCGDYMFAQSIKDKIGLDIQQMWPTINGDKPYTMAFSRSQWCHPIVTMHHMNSEEVATFWDFESSQYNTTDDVKNKPMLVRDIYTKFVAPRVKERIDVWDNMSDDILLFDKNDERNHKWQDWEISRIPKDEEMTPTLRDAYHSAENCKAACDSFGDCFQWRFHNGLCSFSRSFRLGRPHHDDDQGRWVSGWNLSRIQDFIDRESECTSIQWPSPSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6Z2</accession>
    <name>A0ABR3Z6Z2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_003326</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000076">
        <property type="protein sequence ID" value="KAL1895309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033370">
        <property type="entry name" value="COG1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31658">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31658:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08700">
        <property type="entry name" value="VPS51_Exo84_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="693"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="721"/>
            <end position="788"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1895309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="871" mass="97606" checksum="37A975A90D9B9E3A" modified="2025-10-08" version="1">MVAPDTSNLASAADVFAATYTLPQIRAIHKSLHDQAEEKSTRLRNKVGNSYRELLGTADTIVQMKQDTDAVQQILNRMGTNTSSLVLKKKTNGLSRYDQVVVSGDSSVEASEIARAKIWEATNLAFSGTLRGSKAFGLENLGRGERLVLATKVLVLSRVLIASFKGSIPVSQYARKTIGVAEKSLQRSRNKIRRGIAKALGEACEEEQRYVVLKALAAYSLLTNSGAQDALKHFLHTRGVAMALAFELEEDKRELTSVNAMNALKLYTSTLLDVQALVPVNLSRELQSLKKTRLLADTSLQSLQILRLDTYEKWCGDDVQFFTPYIRHDDLGGDRAKSMLLSWANDGSKALLDGIEKTLLQIKEFRTITDLRTQVLQHWVREGSRIKGIDSDEMLKKLRSLINTQLQRILDTKISKIHLVSSEVSSTLDSWVEGETDAVINMWDTTRFDMKMGRGAVPFITEVIAGMNGYNNAVSRAVSRYQAWYSVINDVRDVVEILRRQRWDNDFEEIEAEETIEARQQLLSNDDPRALADRLTGSLQTEFTILEKDLVQLWKSKETSLNSGEIAAYFLRIIRSIRSALPDIPSIKSFCLEVVPELQQVVVRDACISPLDEYVLAVLSKRTVSCRGLWEGEPSLPTQPSPGTFKFLRNLSTSMGDKYSDLWSPTAVALLRKHMARLIKENWVKVLADLEEKEDENDEAPKQESQPIDNATEGIMGNSDENSKPEIKPESESKPELEPKSESMKELEPESKLGSKPESKTESKPESQTEPDADPKDDSVQSCDRGEVPDVTTQDIKEKASLEKKDVVIQWLYDVLYLGNPFSSSEVGNLLKSLEDTLFEHSGLELEAKQKLAKSASDYWKRTFILFGLLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z730</accession>
    <name>A0ABR3Z730_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mediator of RNA polymerase II transcription subunit 18</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Mediator complex subunit 18</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">MED18</name>
        <name evidence="2" type="ORF">Cpir12675_002994</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mediator complex subunit 18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000064">
        <property type="protein sequence ID" value="KAL1896017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.320.10">
        <property type="entry name" value="Hypothetical Protein Pfu-838710-001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019095">
        <property type="entry name" value="Mediator_Med18"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09637">
        <property type="entry name" value="Med18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0010">Activator</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU364150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="285" mass="33001" checksum="15BB825591743AA4" modified="2025-10-08" version="1">MLELFMTAVIDREDETRARAVLKGICARDGYESMNRCLRFQGPRRPTGMSNLVSVHKSDKDKQPSELLIWRELQTAVSRQSYLIDLRYEAPYDGFGPQAQQPDFNANEGILRWLDFPDPPPPNSNRAITTRKKIEIWKQKNLLKIMQDNNHALKGELLEHTVQYFDDNGIEYCLCKQYLLKDRSQYQPMLSPDTRSIASHLPAQEALECGDPMGRWFLFVKINVLEDTRPHEITRAAEKLQVIQRELEGAIEFKHFDRRTWDPRVPLEVRNGPAPLPQVVTVGDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z747</accession>
    <name>A0ABR3Z747_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">UNC93-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_002968</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000064">
        <property type="protein sequence ID" value="KAL1895992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010291">
        <property type="entry name" value="Ion_channel_UNC-93"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051617">
        <property type="entry name" value="UNC-93-like_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23294">
        <property type="entry name" value="ET TRANSLATION PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23294:SF59">
        <property type="entry name" value="UNC93-LIKE PROTEIN C922.05C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05978">
        <property type="entry name" value="UNC-93"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="274"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="311"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="456"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="508" mass="56171" checksum="3C970934E40429AD" modified="2025-10-08" version="1">MSADAPPAMSVAPSIRDEKSGPTDIPPQYSNNDLIRPAGWQYKSFTIFGRELWYASPKVQLFMVAMVCFLCPGMFNALSGMGGGGQIDTKPSNDANTALYSTFAVVAFFAGTIANVVGVRLTLSLGGIGYSVYVAAFLCYNHTQNRGFVVFSGAFLGVCAGLLWTAQGAIMMSYPPEESKGRYISWFWAIFNMGAVIGALIPLAQNVDNDAGPVNDGTYAAFLALTFIGALLALLLCNAKSVIREDGSKVILMKNPTWKSEFIGLYETIADDPWIILLFPMFMASNIFYTYQLNDMNALNFNTRTRALNSLLYWSAQIIGALLYGYALDIGSVGRAMRAKISWATLMVLTFAVWGGGWVWQKDQPTREVVTSKEWESQRIDWTNGSRYYEPMVLFFFYGFFDALWQTSVYWFMGALSNSGRKAANLAGIYKSLQSAFAAIWWAMDGKKVSFDAMFGSTWGFLVVGLLVAGPIIFLRIKDTVSMEEDLKFSDETVEYITAKALTKEQNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7H3</accession>
    <name>A0ABR3Z7H3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002955</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000063">
        <property type="protein sequence ID" value="KAL1896040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1896040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="201" mass="22889" checksum="D4D6DF577D1AA556" modified="2025-10-08" version="1">MAFYPKEKVAAIYMTKNDEESDRENKLGLTEIYNFLAQRKGAVPDEMSLVIFDVDEGDTETHDLIAGIHEGRNLGPLKEVKVLPSDEEWDMILATRYYVKLLQIINKPVQKVIIRDRDHFDFWNKVTHINRIVFSFLMEQKTPVPGTVTDVSTTGLQPDFDGEEQGATPKALLAKEPEDGDLFQAEVNRKSAHQILDVENV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7R2</accession>
    <name>A0ABR3Z7R2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Anaphase-promoting complex subunit Cut9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">cut9</name>
        <name evidence="9" type="ORF">Cpir12675_002745</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000056">
        <property type="protein sequence ID" value="KAL1896649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558">
        <property type="entry name" value="CELL DIVISION CYCLE 16,23,27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558:SF9">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12895">
        <property type="entry name" value="ANAPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 7" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="460"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="494"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="569"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="608"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="569"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1896649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="630" mass="70943" checksum="732633D8B7471DCD" modified="2025-10-08" version="1">MQKFLREWRQDALNKTQYESAIFLGDKLLAMTNDDNDAFWLAQVHFATGNFTRAYAFLVKHDLTNRNPACRYLSAHCMIKQSLYDDALALLGERNPTHLVANSTTNKRKAQPATRSARAGTSKEAAAQEQSRKYEAAMCHLRGLCYTKQNAFDKAKECYKTAVQIDVQCFEAFQQLMANSIMSPEEEWVFLDSLDFDSVSVPGDTAASQEAAEFTKMLYTTRLSKYNNPSEFTTAYESLSTHYHLARNPDLLLARADLLYTQCKFKDAFQITESILAEDRYNFAVYPLHLAALFQLQRTNELFLVSHDLADHYPDEPCTWLAVGTYYFAINKIPEARRYFSKASMMDQHFAPAWIGFAHTFAEEGEHDQAISAYSTAARLFMGTHLPQLFLGMQNHALNNMVVAEEFLKTAYGLCKTDPLLLNEMGVVKYHQDQPQDAVVFFEAALKISADADSEPDAWIAVRVNLGHAYRRLRVYDRALECFDEALRLGGKNTALFTARGLIFLEKNQPDEAAMELHQALAISPQDAIATDLLNKALAESFMFGAAKDDGADDIDAFDSQVLAAVHEPRLRDRDRDRDRDRDRKGKSTVATRSLKAGLRAGPSRRLVGRMHGGLAVGEDGSMMEMTDEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z867</accession>
    <name>A0ABR3Z867_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_002826</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the putative lipase ROG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000059">
        <property type="protein sequence ID" value="KAL1896422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007751">
        <property type="entry name" value="DUF676_lipase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044294">
        <property type="entry name" value="Lipase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482:SF65">
        <property type="entry name" value="ESTERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12320)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482">
        <property type="entry name" value="LIPASE ROG1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05057">
        <property type="entry name" value="DUF676"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="DUF676" evidence="4">
        <location>
            <begin position="10"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1896422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="437" mass="48437" checksum="D66F63EC9EDAF952" modified="2025-10-08" version="1">MTSLSSGDIQASHLCVVVHGLWGNPIHMASVAKALRAKFPQDKLHILVAEANSGSFTYDGIDRGGERVCAEIEAEVQRISDRGGKVRKFSMVGYSMGGLVVRYTAGLLYAKGFLDSVECMNFTTFATPHLGARAPFKGAFSHVWNAIGSRTVSMSGRQLFTIDDFRETGKPLLSVLADPGSIFISGLRKFKNRTLYANITNDHTAVYYTTSISRTDPYRNLNIIKPHFVPGYGQVVLDASNPLMPHVPKPVALSARISAFIHTLPLYATISLLLPIGVVIFLISSIFSTCRSSHRIRMHELGQGGVAIEKYRPPLWVQGIRQEVAHAYEALGSVQGDQFLDTNSSGRDGDDEAMDSDDTRIMTRERRMSIPAQPTLALTPAQFSMIDSLDAVGWRKFPVWIHNDQHTHAAIIVRFEKETFNEGKLILQHFVQEEFEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z940</accession>
    <name>A0ABR3Z940_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Casein kinase II subunit alpha</fullName>
            <shortName evidence="10">CK II alpha</shortName>
            <ecNumber evidence="10">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">CKA2</name>
        <name evidence="12" type="ORF">Cpir12675_002665</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Heterotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="10"/>
    <dbReference type="EMBL" id="JAWDJO010000054">
        <property type="protein sequence ID" value="KAL1896717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd14132">
        <property type="entry name" value="STKc_CK2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045216">
        <property type="entry name" value="CK2_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24054">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24054:SF0">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="35"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU369118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1896717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="336" mass="39340" checksum="7902E01E88423103" modified="2025-10-08" version="1">MPSLARVYPDVNQTMPRAYWDYDAVNISWGILENYEVVRKIGRGKYSEVFEGINVANYQKCVIKVLKPVKKKKIKREIKILQNLSGGPNIVALLDVVRDPQSKTPSLVFECVNNTDFRTLYPRFTDLDVRFYIFELLKALDFCHSKGIMHRDVKPHNIMIDHENRKLRLIDWGLAEFYHPGTEYNVRVASRYFKGPELLVDFQEYDYSLDMWSLGAMYASMIFRKEPFFHGNSNSDQLVKIAKVLGTDALFDYLDKYEIELDPQYDDVLGRFPKKPWHSFVTADNQRYVSNEAIDFLDKLLRYDHQERLTAKEAQAHIYFDPIRNGMPENVPTAQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9L1</accession>
    <name>A0ABR3Z9L1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Arginine N-methyltransferase 2</fullName>
            <ecNumber evidence="8">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">RMT2</name>
        <name evidence="11" type="ORF">Cpir12675_002917</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylarginine (type IV) in target proteins. Monomethylates ribosomal protein L12.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000062">
        <property type="protein sequence ID" value="KAL1896209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019702">
        <property type="term" value="F:protein arginine N5-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017408">
        <property type="entry name" value="Arginine_N-MeTrfase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051038">
        <property type="entry name" value="RMT2/GAMT_Mtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026480">
        <property type="entry name" value="RMT2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32379">
        <property type="entry name" value="GUANIDINOACETATE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32379:SF1">
        <property type="entry name" value="GUANIDINOACETATE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038148">
        <property type="entry name" value="Arginine_N-mtfrase-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51559">
        <property type="entry name" value="SAM_RMT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RMT2" evidence="10">
        <location>
            <begin position="214"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="160"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="160"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR038148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1896209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="457" mass="49784" checksum="E1B0E96D8F3FCE07" modified="2025-10-08" version="1">MSDPISEALAAAPTANPIDDSLAARISTACSSPTREILHHAWVHDKSGLRELLKEPGSASCMDPSTRETPLHAAIRACGPADPEDTGSDGEDGCVEEARDVMQELFFCGAIWNDLDDNDETPGCVALRLGRRGLYEMCVDAGVRAEMLLSLFDNDGYEELDSEDEDAEMNGDDGTAIVEPTEAQDGTESSDKALEQEGNPASVAQASAPTEPDRDVNSEDYLKAQVTYSDGKLVDDGGNGVMMAWETEIMRRSVDALLPDLPAGARILNIGFGMGIVDGMFAATKPSRHHVIEAHEAVLAYAASKNADGSPACAFGPEWEASGPEEGAFKMYAGKWQGILPELLVTGEQYDAIYFDTFGEDYTQLKLFFTEFVPALLAEGGRFSFFNGLGADRRVCYDVYTKVVEMHTTEAAMDIEWIEIPVDMKGMEEAGKGEWEGVRRRYWTLDTYRLPICTMLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9L5</accession>
    <name>A0ABR3Z9L5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7357 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002377</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000046">
        <property type="protein sequence ID" value="KAL1897273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055781">
        <property type="entry name" value="DUF7357"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24054">
        <property type="entry name" value="DUF7357"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7357" evidence="2">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="550"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="680"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="847"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="248"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="371"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="411"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="458"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="476"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="494"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="521"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="562"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="581"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="892"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="905"/>
            <end position="917"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="945" mass="104910" checksum="76B9344413B2B11C" modified="2025-10-08" version="1">MRLRLVVRRAAAPDSRLLWNVPDQVDYPVSQLTAQVHTVLPLYSEANPSSTLEDFVVELIDKNGGSFECLHFQQITDVLKEDDQVLIRPLRQDELYAREITGRIYFEDDGPTVVDGVSYGTLHSISMYPALDEGSHPHSRASKRRRTSYLNASEVETSTPARLMAPTRPQFSTSSNPSNLSKPSHAVGKNQQQFVSENAQINPHFQSPSHPTNLHNQVIQKSPKSMRRPPSPPQAKQSVLRSATKVTSSVLSRSPSSLVAPKKLHKSTKHVDALIAFETQQNDIQEASEPSDSDEPPEEVSSKAPASPLRASQMEKVSADTFDVQTERQGLSPKGTASSHSKKSQGQSPLPRNLTENKAKSKDGDEDMDSSDSSSDESSSSSNSSDASDEPVANPVKNKASPVRRSKTTVSLSSDSDSSSSFSSLDSSSDSSSDSSDSDSSDSDSNPDSSGADEAIRRKSTLSKCNRKPTKAAHATTASTCQAPTSDTLMSRPGKTKTQKRNERRRLCLKARRQGQAQTVVKEKDNTADELEKRRQALLRSLSGYEDLVPETEPWLQPSPEALSQKSQPSLEPKSQTLDVPQKKSSDTRDYDSWRGKLNLYAVECVRENMDLGEPPFPFVQRWYRTQNASHGKRKRRDWDEQATEDQLPYDDADIEDSYYANNSTAHYYDESQNYHGYNDDILGSATQLPPPQDDIPEPPEDLSTLPKLQPRQAKKDMIITYQKWILSVATNWEPVIANVAAIILKVHEDDSLVLRLSYRDRQKEHPEKEYDQATGQRIYRGFEAPDDEDDESNDSETLTFAELIQPRILVDPYAHADKDQVDVDGTFHEAVLKTQLCEQTLLAQNVDDDQKSDTRKSCPSAELGAEAEQDVSYEPPFLSPPPTSASKGLIDSQSHPPGRQSSEGDMEVGPEQAEIYDEAREDVVHLADLSEDSDGHIPDQQNPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA65</accession>
    <name>A0ABR3ZA65_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">DNA-directed RNA polymerase III subunit RPC3</fullName>
            <shortName evidence="9">RNA polymerase III subunit C3</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">RPC82</name>
        <name evidence="14" type="ORF">Cpir12675_002274</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 9">Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000043">
        <property type="protein sequence ID" value="KAL1897546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055207">
        <property type="entry name" value="POLR3C_WHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013197">
        <property type="entry name" value="RNA_pol_III_RPC82-rel_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008806">
        <property type="entry name" value="RNA_pol_III_Rpc82_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039748">
        <property type="entry name" value="RPC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12949:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12949">
        <property type="entry name" value="RNA POLYMERASE III DNA DIRECTED -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08221">
        <property type="entry name" value="HTH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05645">
        <property type="entry name" value="RNA_pol_Rpc82"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22536">
        <property type="entry name" value="WHD_POLR3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase III subunit RPC82-related helix-turn-helix" evidence="12">
        <location>
            <begin position="9"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase III Rpc82 C -terminal" evidence="11">
        <location>
            <begin position="201"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase III subunit RPC3 winged-helix" evidence="13">
        <location>
            <begin position="517"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="440"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="454"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF22536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1897546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="678" mass="75902" checksum="5D742129E98FE46F" modified="2025-10-08" version="1">MVMTKHSAELCTLLVRDIYGELPSRIIAGLFNRGPSTISQLGQLTALSPRHLRHGLAVLVQQSLVYHHLSPTGNKQTIYEANPYTSYNVIRLGKIINNVGFEYGTAEQEIVQTIASLGHAQVADLAQAFSARSSAAAASRAAGATKAGNEADMTCFELNETKNVEANGQQDGQQDGASLAIDSPTEPESAIKGTWHLHEVIAQLIQAEILDVIVPGSMRKLHDVYDEIEQNFQRKHKDASAKARADMHLEMVKEFRDARAQTKRLKRDLDSGLIASKRRKLNFNGDSVSDESEFEGRQLASNTVVRINYEKCNVNLRNERLVRFAADVLGETTGQVFSTLLRILTKGISRCRPDLRVDSAAVAEDEFSGPQKIVTTLEILDQLDSSINVHLGIGKADKAKIDKDAAEKIRISALDTEDEDDSDGETGVTTLRPKQASNVTVDIDSDDEPASKGTEGTATEVNGSSTKDSRTMMLRQHLLLLAEHKHRFIRHCGLQGRGQWSIDIELLMDTLRQVELDAIITRSFGRHGLRLTRILQQKGRLDEKTLASLALMKKQAVQNKILDLQQGGFVEIQEVPRDNNRMANRTMFFWFCDVEATKKAVIENLQKMILRCLERLDYERRAEKDLLEYVNRTDVKGKEEQEMSTEHFQRYSKFLGLQDKILGEVQRLDDMVALFSDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBE1</accession>
    <name>A0ABR3ZBE1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_002285</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000043">
        <property type="protein sequence ID" value="KAL1897557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018228">
        <property type="entry name" value="DNase_TatD-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050891">
        <property type="entry name" value="TatD-type_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10060:SF15">
        <property type="entry name" value="DEOXYRIBONUCLEASE TATDN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10060">
        <property type="entry name" value="TATD FAMILY DEOXYRIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01091">
        <property type="entry name" value="TATD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1897557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="389" mass="42870" checksum="A07795EA80AB83FD" modified="2025-10-08" version="1">MATSAQPHLASGKPQFIDIGINLADPIFRGIYHGQQRHNDDLPAVVQRAIDTGCQKMIITGSDFASIRDAMVISKQYSGTVFRTAGIHPCSSAIFGSCPPRQSKGQTPACGLDLAMEEATEAVPDQERTAVAIAQLKELIDESSSSKSLVALGEFGLDYDRLHYCNKAIQIHSFDEQLKLAASMKLQLPLFLHSRAAHRDFVDLLKKHYGPCLEKLEKGGVVHSFTGTIEEMTELMDLGLYIGVNGCSLKTAENCEAVKAISLNRIMLETDGPWCEVRPSHEGWKYLLPSEGHTQADVASTIIDPKVPAKKKNQPKKPEPKITEVTDIYKVVKKEKWVEGCMVKGRNEPCMIGRVATIIAGIKGITVEELCKYAWENTTKVFRVVDDCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDG8</accession>
    <name>A0ABR3ZDG8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Structural maintenance of chromosomes protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">SMC2</name>
        <name evidence="14" type="ORF">Cpir12675_001729</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SMC family. SMC2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000029">
        <property type="protein sequence ID" value="KAL1898726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03273">
        <property type="entry name" value="ABC_SMC2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027120">
        <property type="entry name" value="Smc2_ABC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43977">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="Smc hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="7 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="13">
        <location>
            <begin position="521"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="246"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="340"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="424"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="683"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="761"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="814"/>
            <end position="897"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR005719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1898726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1180" mass="132587" checksum="968212EEF6C70199" modified="2025-10-08" version="1">MRVIEIIIDGFKSYAVRTVISGWDESFNSITGLNGSGKSNILDSICFVLGITNMSTVRAQNLQDLIYKRGQAGVTKASVTIVFDNRDKAKSPIGFEEYATISVTRQIVLGGTSKYLINGHRAQQQTVQNLFQSVGLNINNPNFLIMQGRITKVLNMKAVEILAMIEEAAGTRMFEDRRDKALKTMAKKDLKLQEITELLRDEIEPKLEKLRTEKRAFLDFQQTQNDLERLTRLVVAHDYVRLQEKLQQSGADLDGKKQRLKDLQESAIRLKSELSHLEEDVTRVRSQRDKEMKKGGKAAALEDTVKKHSNELVRLSTVIDLKKSSQTEELEKKSAVKKTVLELEASLQEKTKLYEHAKAKYDNAKEELEKQDRDVESKEELLQTLQTGVASKDGQESGYQGQLQDARNRATTTATEQEQAKIKIAHLEKRIQEEEPRAQKAKEQNATLLRDLEIMKAKAQDLETKMAEMGIEPGQEEELFKQEATLEQAIRDLRQESDALKRKVANIDFNYADPVPNFDRSKVKGLVAQLFSLDKGHLNAGTALEICAGGRLYNVVVDTEVTGTQLLKGGKLRKRVTIIPLNKISAFKASAQAIATAQKLAPGKVDLALTLVGYDDEVSAAMEYVFGNTLICADADTAKRVTFDPNVRMRSITLEGDSYDPSGTLSGGSSPNSSGVLLTLQKLNNITRNLQQTEATLKALQIKIATEKSRLDKARQIKQKLDLRFHAIKLAEDQISSNSSSSIIHEVETMKQTVTRLFADISNAVKRHAEASADVKRIEKDMKDFDNNKDAKLIELQKSLDKLRVSFTKNTAAVKTLQKELQSAQLDSEQAGADLSAAREQLHEVDLAIKAQQEEIEGLTKQQALVQEEYTSIQASLDDERAKLHVFNDELKALEEATRSKTARITEESLEMQTLGHETEKFHKEQQDARLAVTHMEEQHEWISDEMNLFGRQGTPYDYKSQNIRECRSTLSNLTERFQGMKKKINPKVMNMIDSVERKETSLKQMMKTVLRDKRKIEETIVSLDEYKTKTLQKTWKKVNADFGQIFSELLPGGSFAKLDPPEGKSISDGLEVKVCLGKVWKQSLTELSGGQRSLVALSLIMALLQFKPAPMYILDEVDAALDLSHTQNIGRLIKTRFKGSQFVVVSLKDGMFQNANRIFRTRFSEGTSVVQALTPADLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDK5</accession>
    <name>A0ABR3ZDK5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Glycerol channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">FPS1_1</name>
        <name evidence="9" type="ORF">Cpir12675_001867</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000032">
        <property type="protein sequence ID" value="KAL1898404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00333">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050363">
        <property type="entry name" value="MIP/Aquaporin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00861">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829">
        <property type="entry name" value="AQUAPORIN OR AQUAGLYCEROPORIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829:SF9">
        <property type="entry name" value="AQUAPORIN-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="170"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1898404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="319" mass="34989" checksum="03843965EBC49B23" modified="2025-10-08" version="1">MGIYSDDLEKGYQNPYYTPEPKLTAMLEYFQDFISEMAGTFTMLWFGLGVNAQVFLSKNSAGDFLSINIAWGCGVFFGYLVGYRSGGHLNPAVTITNVVLRGFPVKKLPFYISGQLLGAMVACLVVYANYLVPITTYDSSTGDHATSLDNSSARIFTTYPQSFMSLEGRFFSEFVTSAMLMIGIYVLDYTCKKGISKVPMPIGLAMLVMALGMSSGWETSYALNPARDFGPRLVSYLLGYGTEVFSASQWYFWVPLVAPCCGCLVGGAVHDLVSGNDESPLRQLLDWISGDSIIKRKRRELILLHSAASSTKSVDTLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEE3</accession>
    <name>A0ABR3ZEE3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001591</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000026">
        <property type="protein sequence ID" value="KAL1899035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052953">
        <property type="entry name" value="Ser-rich/MCO-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883:SF17">
        <property type="entry name" value="CUPREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883">
        <property type="entry name" value="SERINE-RICH PROTEIN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045596156" evidence="2">
        <location>
            <begin position="28"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="211" mass="23104" checksum="E9E41C3594179BAE" modified="2025-10-08" version="1">MDHIAPVFSFTLTFLFLSLLTPKSSISTTTTISVIVTIFVAKMRFSFVALLSATAALAAPSQVSEGKKLEAREGFTRIVQVTEGGIYPSQLQANQGDFIWFKFGSGFNSVVEGEYNRPCRSYGNGFASGTVYHSGNGFFGRVFIVDVGNTSPRWYYSGEGTRCIDKAHVAVINPPSNNPNAFASYYSSAPRAKRVDTHSERGGQFENDEEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEG1</accession>
    <name>A0ABR3ZEG1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001615</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000026">
        <property type="protein sequence ID" value="KAL1899058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00063">
        <property type="entry name" value="ALDOKETO_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="26"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="302" mass="33959" checksum="2B9DECEB1D63C15C" modified="2025-10-08" version="1">MTSANVFENTYRKVFTLNTGDKMPALGLGTWQSKPNEVRHAVKAALDAGYRHIDTALAYGNEKEVGDGIKDSGVPRDQIWLTTKLDNPWHKRVAEGIDSSLKSLGTDYVDLYLMHWPCSSDPDDMSKVFSDWDYVDTWREMQKLVGTGKVRNIGVSNFGIQHLERLLKDPQTTITPAVNQIELHPGNPSPKLVEYCRSKGIHPTAYSCLGSTNSPLYTNTTLKQIADSKNHTIQQVLLMWGLQKDWSVIPKSVSASRIQGNREVDGWSLTDEEVKTIDDITDRFKVCGDAWIPIRVFFGDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEI8</accession>
    <name>A0ABR3ZEI8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histone transcription regulator 3 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">HIR3</name>
        <name evidence="7" type="ORF">Cpir12675_001620</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Has a role in a nucleosome assembly pathway that is required for the integrity of heterochromatin and proper chromosome segregation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HIR3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000026">
        <property type="protein sequence ID" value="KAL1899063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033053">
        <property type="entry name" value="Hir3/CABIN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15502">
        <property type="entry name" value="CALCINEURIN-BINDING PROTEIN CABIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15502:SF7">
        <property type="entry name" value="CALCINEURIN-BINDING PROTEIN CABIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="379"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1557"/>
            <end position="1610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1865"/>
            <end position="1898"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1956"/>
            <end position="2275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="411"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="440"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1575"/>
            <end position="1598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="2005"/>
            <end position="2015"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="2047"/>
            <end position="2060"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="2116"/>
            <end position="2131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="2140"/>
            <end position="2152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="2189"/>
            <end position="2236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="2245"/>
            <end position="2275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="2275" mass="252787" checksum="2C1EB4C7365BB48D" modified="2025-10-08" version="1">MPAFQAINVEIEETVENELETIRELHVDDALKLFQYALKLHAQGPDSFAAAADAYDDLFKSEIFNYPEAATEYERAERRPDQPSFLDLAVVDSDGTGTSLPQALYLAHKNRGQFHLDKIRHEAKIAAGPRSAFFARPDTIKQAQLCLADFTAALDRDPSDAELWRRTARVAAYLQSARTVRYCLESAIEMDDDPAVVDVEPPSIAEVLAGQQLKDHLAKLGDEMAVSHPIMAPWLKTRIPALLQKSLDPIPFLPGLSKPASIDQATDTETETNSTLKADEHVIAVAKTSWTNIGIALLVYWSTHGPTASRITLSFEDLKELEDLHNVEELQDLSDGAAMDKMLGDSPKTTLDLGKDEAKVPPTLLSQTLANVNTTGVVATVEPPEGSNDDLNSSSDPAAITADATNIPSQQHERSVETRDTSANNGTSRKRSQSVAGVAEPREETMLEKRSKRTRRRETVEEIEDPSTRIAAQLAPIQAADKNLFNVTKNIMENLGVTDKDTMDQLNEMIEVCASEDRSTKISNPAVDELQAMLLTYKEDAVRIMISKKNMTLSLSSFLEYSKSSAPQQTQPMVFQEKKGLASFQQRVNDEWWCCSDMVFEWLKRISTTYLTQQWPDALKNTVVQLISRVDSPLYERITIECASTGVIAGAVSGRGPIAGSPAWTQARAVAQMLLELHVEVYGALVRAGAVTSDERRAEVGIRVSRWQSLCSGLCLDSPVREAHKDPLTVRLVWVSVATLALTTESTNRDHILASWTELRDLFVDNSLAGCDLPNNGFLGPMSGAAADREISKLTTMDFFLSIFRDEMKDPVHVIESLEPVLNPQTVAVTIPINSDDAPTASIPQLPSSIADEDLTQDANTSTDSTVTDGVGGGVENAQGNMVPIMECASQRLRDLWKFMESSDAEVRLFMWTRLAEAYSSIDYISKEFSCNLRSIEMLVGEITGPTVRQTAPELRALALVKPLKFLDDLVVVTLNMTLNISASTNGSDPFEIIDGDHLRASCGAVTRAIVFLHNVAMLEDEVRIGMITQKTYNNSFQAFLTKLRYLQVRLWCLLYALVRFGVQTNLQTFPNPETELADYLAAIHQVLGPRKYCRSSNKIFLQLMRQELLKFSTIDNWEDYLGQVLYDLHGLRLGVGLWEVQEHHCAPIGLERKHALALVERVMILAQAMPMKDLLRSDLKGAIEQLQKAMGQSKAMPAMIHNIRNYTELMKRPILALPLYQAENGALMLNAVTVKSTPDWVLARHGWYHLLGMMAFTRFTSLELMKRQTPGAIDDLRIATTYFRQQLQFVPDRWDCWLRIAQCFDYELDEAVLWTADRMNRDRADLVKLQRQAIHCYILALSYSWTERSWLVSYMKQRQEKGLGMLADDKGRRNLQGLDIDTIFDLYYCFGYRLYSSSREPFAMDVFCHANCQRFFIELSSYDTFQKQAHEEMTPYRVWKFAGQMFRRAIMLKPQDWKSHYMYAKCLWKMYQATDEDIRGTSSSSDSNMSTNRPTVTMVLKALQKSVAVASARTKNSRSAPVIEPHYKILSVAMKLVARGDMSPIDAASMLSKQPFGVPLHGQKDSDDDEDNENTTATTTNNNNSNNNSDDNGSTTSHELPQGDDEDDQEDWWESYTIRSLCLLREKDKSNWQHRLIIRQASTLLGESVETGAVIDFIQARATFNVLRDSMFTKTMAMNVWKCDAERPGRHYVYTERYTRFMVKLLGVLGDHENLELILRRIRKKGTDFYHFTDLWQMCCMEHMRVLRKAYKIPPLTEEEPFKTWTLDQLDKVAELIIKWAAEAAASCSSDDQATGQNGGQPSMIPPMACLKDSVELRKLNAGLLKAGGIDDLIVDAFSRVFSACSSDCPEILAAIEKEKEKEKPSLPLSALVPEPTTSQQHQSADGDATITEGGDTSEAPAATAIAAPAAQLPEAPVAPAPKLRRVMARRPDIIRKAEQIVTILADVLAGGNAKPNATVAVGLGTKSRSRSRQDSSGTRDPSPAAENIQEDTVMKDTIMDMGDNGDDDEEEDDGGRGGNDDEDNKADETALGGDTELMDTELGPNYTTQFGDHSQSDAADSYLESDLSDIPPDYDDDAPPFTSILFPNLVRKGPTSDSKVSRLGDDANGGSALLKDRETPGKTKAKAEAGLDLEAELEASASASGSADTGAEAEAETEAQNEPTTRIGEPGLKSRQISVKLQRTIEAEEGEEEAEEEGEEGEEGEEGDSEDIGEEDDEDDEDEDDEDDDSDSDEHYDGPTLDVDLELPEEAEDGVEADDEDEGDDEDEDQTMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEW7</accession>
    <name>A0ABR3ZEW7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PLC-like phosphodiesterase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000029">
        <property type="protein sequence ID" value="KAL1898737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051057">
        <property type="entry name" value="PI-PLC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593:SF143">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C X DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="614"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="797"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="616"/>
            <end position="634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="924" mass="103764" checksum="E1281B09CB17F253" modified="2025-10-08" version="1">MNLTRATWEDTRMFALVMNHSNVDSLSSPSDCSGPNLTQSCFWYTQAASIQSCYNEPATLMSNPEKRVIFGERKFSGTAYFSVINGTPYTMRLLKAESSSAIQVLVQFGGRNNHRGSGEVVYELVGSQDRTFKFRAYIDPQPRPYGSLHVMDVVHTDLPTQDVSNGDTIKLRFPGPGVRGRAMQWALVGSDLDGYWTSQNPPVAWMQASRYVIGDRKLKHVCMPGSHNAGMSTINGRTTFVTPSNAQNQILDIYQQLVRGSRWLDIRPCVGNSSNYMLCHYSNRFGANGISLNDAISQINLFMTEFPGELILIDLNADSAYDTSRGYSRLTSSQWDYVISHFQNIEQPCRTAGNLSETTMDTFIGDGKGCVATLKRSPIPQTNESFHGIYNENALPRLNVWSNTGSHTEMAIDQVRNLQMHRAIGHESDPSTQDTFHILSWFIKPPPLTFRRAWRYKQIVNHAGEALSTLSSFGISEFSPYSFPNVLYVDALGMPHGGVAAGAFAARDQKFEASTPHMAAMAMAINYAIVSRNCYVGGHQISQIWRPMPDVLEMPGLEGASETQGVQEVQEAQELPEIPDVQQTQDAQGSEEAQEVLEVSEIRVIQQVQEAPEIQEMQQTQDAQESQVTRTQEGQNDLEMQEFQQVHEAQDIQEPQEAPEIQEILQTQDAQDSQRVQEVQEVHETQDFQGFQEAQEAQEFQEFQEFQEAQEIPEVEKFQQPHEAQDVQEIPETQQIQNTQGLQEAQDILEILEAQDTQVQEALETQEVQHTQDVQEFQEIQEAQEFSEVQDFQQVHEAQEAQGTQEAPEMQEIQHTQDSQEEVSGIQEFQKFQEVQEVQDAQDAQDSLEVQEIQEFQEFQEVAVTLDASEESEVSSLSEKPTAFDASNESNVLEISPALDESAVPDTSVVPLPLVSGVLDIPEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF19</accession>
    <name>A0ABR3ZF19_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Extracellular serine-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001772</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000030">
        <property type="protein sequence ID" value="KAL1898665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00920">
        <property type="entry name" value="Cupredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052953">
        <property type="entry name" value="Ser-rich/MCO-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883:SF17">
        <property type="entry name" value="CUPREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883">
        <property type="entry name" value="SERINE-RICH PROTEIN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046620890" description="Extracellular serine-rich protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="255" mass="25026" checksum="9D025D4DF4598FE6" modified="2025-10-08" version="1">MQLRFALIATLVSAVLASPAPSSEGGSSSSSSSSGSSESSSSSSSSGSTSGSGTETFAVRVGMDATGKTVLKFSPDTITAPVGSVVQFQFMGGNHTVTQSSFDGPCVPISETSSAVGFHSGFVPAAASVAKGEIPVYSITINDTKPLWVYCAQGKHCQSGMSMVINENTASNSSRSLANYRTAAANVAVAKAPVEGSTSGGTAGLAPAPSSGLGSGSASGTGALSSGTPIATAAASKIGNNFVVPGFLAYLAMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFA4</accession>
    <name>A0ABR3ZFA4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HTH La-type RNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_001414</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000022">
        <property type="protein sequence ID" value="KAL1899378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07323">
        <property type="entry name" value="LAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045180">
        <property type="entry name" value="La_dom_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006630">
        <property type="entry name" value="La_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792:SF132">
        <property type="entry name" value="LA-RELATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792">
        <property type="entry name" value="LUPUS LA PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05383">
        <property type="entry name" value="La"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00715">
        <property type="entry name" value="LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50961">
        <property type="entry name" value="HTH_LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="HTH La-type RNA-binding" evidence="4">
        <location>
            <begin position="516"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="60"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="161"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="725"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="60"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="138"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="172"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="214"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="241"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="299"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="312"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="340"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="363"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="376"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="406"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="420"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="436"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="728"/>
            <end position="742"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1899378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="749" mass="80542" checksum="620FF9605E5E6F03" modified="2025-10-08" version="1">MSTPTPFSYAQAAKGSAPAASVPTANGTASPAEGKTNEPIADSNDINTKVGIEATIESINSNTAASVSGSTSSSANDATTCSTASIRDEDEQTTDAPTRRSEAGPRAGSASRRQEPKKARQDKKNKESSADVAFVAEPKPEASKAELYEAPVPPINIWQQRLKASTVRPTPATEQQRPTEQGVKSKTANGAPPTTKTIESAESETGSRKSRGGRSFERELASKDAEQIISDPVNWPTPETSMKEKASSTKTAEKPTETAEKESQEDTTTASGKAKQLGKKVWEKVEFTPTARFETQMPSTRGARAPRGGARGGREGSSRGHANPSKDGEKSSSGTPHGAKSGDNKERTRDANAPRNNSLPPKKFSDAAPKEQRKNASGSAASQAGSAQSPVRDTSVVPATESSFTPRERNETRGERTRGGNRGRGGYHGSNGPAPINTQQPYTNGFVSNSTPRQSIVSPLRQSSYTGNSYNNTQPRSHGRGGRNGPRMSGQNSNYNHDYNMQGMAPAYPVMNYYDPSQAYWTLNSLSQQIGYYFSVNNLCKDVFLRKHMDSQGFVPIQVISNFKRITDITVTMEADPLELFREACAQLAVPGPDGTALIEFVVGDDNVERLRCSSGWDKWVLDVSERAEPYRNNGPASFTPHPRTGMNAYMNQFFPMYPMVSPTVPNGTSQFQGYPQQHSYRNSTPVYNNGFNYPNAGNNVYAPSFNTSQLSAAVPEFSPLAASFPSTEQAAAATDEPTATESNASVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFW1</accession>
    <name>A0ABR3ZFW1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Kinetochore protein fta7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000030">
        <property type="protein sequence ID" value="KAL1898693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025212">
        <property type="entry name" value="CAD_CENP-Q"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13094">
        <property type="entry name" value="CENP-Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="261"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="360"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="312"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="90"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="140"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="270"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="367"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="466" mass="51424" checksum="ED4D28232FA05D9B" modified="2025-10-08" version="1">MPLKPRSRGGRNRAKTRASPIEDAPSHEPHLQTRSRRQRTSVESLELPDNPVASKARLRKTRRQTGRETAGAQAQDETETTSSSSRAKQRRDENRQKRRESDQAHGPEVDSSLEHESPHSDHENSGFEEPAPPKRKRGRSSTTQLPTSPTSKRKRLSQSRPANDLVHSPQTSTLNPGAQALVDSVPRKYPYLAPRVRHIPRSVIEEKWTPLEASSQATIKAILHLAAQPALTRAGTNATRHKAGLAAIRAVSKRIQSKLSRGLPFPPASPGGVPVRGGPVVPRRRKDTDAGRADELDFEKTLAGVNVLEEGLDTLLHSVALLEKERDNLVQQIEKEHERAVKLEGDVKKEATMWKESLRKAHALTPGKTQQDSSSGDNDRAPHLFSTPDTNVLPGEAFRNLDAEKGEVVEEVCDLARQVANHMESIRGNMAQIEGIIPQIGRTRAALQVVLTKNLDTKQVQTVMLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFW4</accession>
    <name>A0ABR3ZFW4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphatidylinositol-4-phosphate 5-kinase</fullName>
            <ecNumber evidence="4">2.7.1.68</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MSS4</name>
        <name evidence="4" type="ORF">Cpir12675_001569</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.68" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000025">
        <property type="protein sequence ID" value="KAL1899285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016308">
        <property type="term" value="F:1-phosphatidylinositol-4-phosphate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17303">
        <property type="entry name" value="PIPKc_PIP5K_yeast_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.810.10">
        <property type="entry name" value="2-Layer Sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.800.10">
        <property type="entry name" value="Phosphatidylinositol Phosphate Kinase II Beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027483">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002498">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027484">
        <property type="entry name" value="PInositol-4-P-5-kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023610">
        <property type="entry name" value="PInositol-4/5-P-5/4-kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086:SF8">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01504">
        <property type="entry name" value="PIP5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00330">
        <property type="entry name" value="PIPKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51455">
        <property type="entry name" value="PIPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIPK" evidence="3">
        <location>
            <begin position="370"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="29"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="147"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="198"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="838"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="29"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="75"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="99"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="147"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="224"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="844"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="860"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="915"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="979"/>
            <end position="990"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1899285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1064" mass="117615" checksum="BD17B0D8DE30B1EA" modified="2025-10-08" version="1">MPSYDTTFHQPDDASPMHHLHHHHFEPQSFANNQSETPNLTPASKPTLDHPQDHHEAISSPRHHHHYDFPGPEYNDTSLHSASTPTPVDDRFDQSSVISSSRLSFTTTASTTEDTDQDPEQIRGLNPDHFLVQADLHNLPSRKPSVVSMSVSSMTATAPSMAPPPPPTSMAPPTSAPPLPPSLSSRMASLDLKSVNNRGSLETPIRPASLPAGSGVQPQDHRSAPGSGSGFAPASASASRLSATALRPEQPTSAPPPPPSSGLKHRHTLEVPKPQSTRTSRDSGDMAAYASGRFSPTAVPPPNITTTRRPSLSIGRRNTRSMQSDAPRDEIVVDDDARRWAEAVRQKRASKRRRKEEEDDDRVLVGTKVDEKHANWVTAYNMLTGIRVSVSRTNAKLDRQLTNADFDSKQKSTFDIAGNELVPSAKYDFKFKDYAPWVFRDLRKLFRLDPADYLMSLTGKYILSEMGSPGKSGSFFYYSRDYRYIIKTIHHGEHKFLRHILKDYYQHVKDNPNTLLSQFYGLHRVKTPFGKKIHFVVMNNIFPPHRDIHQTFDLKGSTIGRDYNEDDIKSNPRATLKDLNWMRRKRHLELGIQKKQLFMDQLQRDVKLLQRLHIMDYSLLVGIHDLSKGNDENLRDKTLQVFNPGGEHGVPGGMGDEGDDETGIGGPGFNNNNSSINVGTGGCVGAGNDSNPTVLLRTPSKLESARKARELREMIRQERPIPMAQAASRMPEELDTSHRQHFLFNQDDGGFQATHEDNQPANEIYYLGVIDCLTKFGFIKKMEHFWKSLNNDRTKISAIPPEEYGDRFFDFIENMTMSPEEAQREELCLQKEAESAALARANERSSTWGSRSRLSSAAVPPMPTQAPPPPPPSGLSARRSADTHLTSGVGEPANVLPQTKINEDTALPVVHESGESSPARSGSRASRQQQTESMASQSQQEQYQQHQHQQYRPRTPNASKATAAATAFMPGAPPPTPPKSDHHLNLKPDSADSGYYTAGGHPNNSHSHSRKLAVSTTATAPAPKPTPASIANTNTPAHSRGQASIDKELPSLPAGDAVVRPVYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGC9</accession>
    <name>A0ABR3ZGC9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">SNARE-complex protein Syntaxin-18 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_001535</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000025">
        <property type="protein sequence ID" value="KAL1899252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019529">
        <property type="entry name" value="Syntaxin-18_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15959">
        <property type="entry name" value="SYNTAXIN-18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15959:SF0">
        <property type="entry name" value="SYNTAXIN-18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10496">
        <property type="entry name" value="Syntaxin-18_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SNARE-complex protein Syntaxin-18 N-terminal" evidence="9">
        <location>
            <begin position="2"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1899252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="326" mass="36100" checksum="99B68DBCB685F48E" modified="2025-10-08" version="1">MTDLTPEFNSLLKGLEAPQTKRYQLKIDDVDAFIREAYRVNALILDLHSELKDVRKAYLSTAPQRKSHLRIAQPTRERVMTDHEREDIDANAKQMIRELNASIRALDDAEQLRRETLAAVHTKRFSGGGLGLGALGSWAAGGLVSRTAKSSEQVQAEEAVAQTTLHRDGVLWLLRRRLELCCATQQHMMKTRLTRELEKNKSVLARSAVGSVPLPGVQPGTTKQRIAANGLPPDDELAGMTTSEARFDSNGMELTQEQVQMFEQGNRAMMEHYENALGKVRGAEKSLVEISELQSMLVNNLATQSANIEQLVADSLNTTENVGGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGU8</accession>
    <name>A0ABR3ZGU8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Elongator subunit elp4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ELP4</name>
        <name evidence="2" type="ORF">Cpir12675_001668</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000027">
        <property type="protein sequence ID" value="KAL1899008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008728">
        <property type="entry name" value="Elongator_complex_protein_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05625">
        <property type="entry name" value="PAXNEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="113" mass="12163" checksum="19BC5F27A1159A59" modified="2025-10-08" version="1">MLTIPADLYPTSSGLGKWIELMHDAVAHLIPTEPQPANNETSDATETTQGYMKMRRLPVYNEKGGGLEDNNLGETLSFHISSTSGLVIVPLVLPPAIDSAPVEPSSSKVDLEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGX2</accession>
    <name>A0ABR3ZGX2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MutS protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">msh1</name>
        <name evidence="10" type="ORF">Cpir12675_001326</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000020">
        <property type="protein sequence ID" value="KAL1899649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="entry name" value="MutS, connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017261">
        <property type="entry name" value="DNA_mismatch_repair_MutS/MSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF34">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55271">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53150">
        <property type="entry name" value="DNA repair protein MutS, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="9">
        <location>
            <begin position="941"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="46"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="667"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="103"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1899649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1076" mass="119106" checksum="4772F702F2C1CE81" modified="2025-10-08" version="1">MAANSWRSGLRWRNFEVKQHLPFGIQQNSLGSNLFRLTPVSTSRLFTPNSLREKSTQARPLTRKRTKAAEKLTIKLSDLPQGRLESSPENNPDEQLASEKNESLNSGMEDNASFNTDAKTNVDTNADAKAAKYPAVITQAHSNMQRFPNCVVLTRVGSFYELYLHQAEEFGPSLGLKISQKKTVAGPVSMSGFPFFQLERYLKILVQDLNRHVAIVDEFPKTEIERAKSGGLMHDRKVTRIVTPGTLIDETFMDPYTSNYAMAIHVDLPSEEPPSTREDQSSILAVATTTQLGLAWMDLSTGQFHTQLTDLASLPSILSRTSPREIVLDKALALSDSSIPPPPVTDYLSESRFFKLARALHSVLIEERHIISYSNPGHLSTLKSWEPVLEGPISRDLAVQFSDFEIKAGSLLLGYVEDRLQGSSIKLQTPKRHKNLNIMTIDKNSLRSLEIKKTMRDGAHRGSLLHATRKTVTRSGARLLADWLTSPSTDIVKIEERLDLVSLFHANPDLRDTVIVLLKRSHDSQRLVQKFALGRGNPNDLLGLAATIQATQEISQLLINAGNKDSTIDTSCTSSLLDRFSLDGPAKLAKQIYNTIDEEGLVHQHEIEESAASHMVALAEETTNSEDTQTDSMAMPKPTVKISKKIGNKAPTMRDVYGEDNEIWVMKPSASRALKKLHATLESLKEEKEQLCTTLRERYSASSLTLKWVPGLGHICHLKGKDIQNASVLSQNMPSQAHVLRASRTTRTFYLPEWFSLGARIDQARLSIRAEEQRVFASLREKVISNLIKIRRNSEVLDELDITTSFAVVAENKNFIRPQLTTSTITDIRGGRHPTVEGGLHDHGRSFTRNDCYLGGPSRGTLWLITGPNMAGKSTFLRQNALLTILAQVGCFVPAESAKLGIVDAIFSRIGSADNLYHDQSTFMVEMLETAQILRNATPRSFVIMDEIGRGTTPSDGTAVAYASLKHLVTLNKCRALFATHFHGVADLARKDKLLCDENDGTTGAIEAFCTDVEEDKDGGFVYVHKLRPGVNRQSHALKVAKLAGMPEVAIDTAESVLAEKGIVTQLRTHGSGDDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH37</accession>
    <name>A0ABR3ZH37_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cell division control protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CDC3</name>
        <name evidence="6" type="ORF">Cpir12675_001130</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01850">
        <property type="entry name" value="CDC_Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016491">
        <property type="entry name" value="Septin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="5">
        <location>
            <begin position="169"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="76"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="515"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="76"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="515"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1900025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="545" mass="61168" checksum="7918B2553F611EE2" modified="2025-10-08" version="1">MVVTLPANTPLPMVSHEDLQSQKSARSVHAHGSSLASGLSVDSASGPAALLDNNGKLARGGDHLGLVSDIYDASTHHPTREMDGESRSQKAHSSRVPSEGSAHAELDGAKWSPVPKHQRDSSASTAPSASPSPVPVAAVDPQNVVRRKLTGYVGFANLPNQWHRKSVRKGFNFNVMVVGESGLGKSTLVNTLFNTSLYPPKEAKSPSMDIIPKTVTIQSISADIEEAGVRLRLTVVDTPGFGDFVNNDESWRPIVENIEQRFDAYLDAENKVNRMNIVDNRIHACVFFIHPTGHSLKPLDIEVMRRLHTKVNLIPVIAKADTLTDEEILAFKSRILADIKYHGIQIFEGPRYELDDEETIAENNEIMSKVPFAVVGATNEITVADGRKVRGRRYPWGIIEVDNEEHCDFVKLRQMLIRTHMEELKEHTNNLLYENYRTDKLLAMGVSQDPSVFKEVNPAVKQEEERALHEQKLAKMEAEMKMVFQQKVSEKESKLKQSEEELYARHREMKEQLERQRVELEEKKSRLESGRPLEKEGKRKGFSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI33</accession>
    <name>A0ABR3ZI33_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cyclin C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_000950</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000013">
        <property type="protein sequence ID" value="KAL1900368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20525">
        <property type="entry name" value="CYCLIN_CCNH_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031658">
        <property type="entry name" value="Cyclin_C_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16899">
        <property type="entry name" value="Cyclin_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0195">Cyclin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin C-terminal" evidence="3">
        <location>
            <begin position="126"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="278"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="278"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="307" mass="35012" checksum="30F5DFC3EC0D4C9E" modified="2025-10-08" version="1">MECIDDSRYRSSTQFQLWSFSKAKLRDLRTKSSEIAKAHIASRLAGEVEGPIEFLSVDEEADLLKLFIVELLRAAEFCELPAEIRATAAVFMRRFSEKFPNTSPEEIVAGEFLLCQGIRFAFDVRHPFRALEGAILELRRAYPADDIRIEEAHHRSREILKVSPLVTDAYFHYTPSQIMLAALAIADQELVDRIFDLIANAAGPNASADDNEIAKQKIYETITACQALLATELPDRMNTYWGTSECNKALRPLQKKLRKCRDPDRIDLVKLQKARRELSTRVEKEDEKAREAKRRKVSTEDPFGPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI37</accession>
    <name>A0ABR3ZI37_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aminotransferase class I/classII large domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_000960</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000013">
        <property type="protein sequence ID" value="KAL1900378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF77">
        <property type="entry name" value="8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="5">
        <location>
            <begin position="32"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1900378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="421" mass="45880" checksum="4ACBB543BE648691" modified="2025-10-08" version="1">MRPLEQQFDSLLERRRAGSLLRQLTIPSSRAIDFSSNSYLSLSINPVITQSYLDLLTTHQDKALIGSGGSRLLDGNSAFTEQLEHEIARHHRAEAGLIFNSGFDANCGIFSCVAQKGDVVVYDELIHASVHDGMKMSRAAHRIPFSHNLVEAASKKDPHSRALKDVIEGLGEDALKGQCNVFIAVEGIYSMDGDVCPLVDVVNCVERCLPRGNGYIIVDEAHSTGIVGLDGRGLVGHLGLEDKIFLRLHTFGKAMSCSGAAVLCSTITRSYLINYSRSFIYTTAPSLAFLLAIKAGYDFLVSGKAQALINHVQELMAFTHGQLTMLNNRLHPPSDIISISRSSPESPIIPVITPAPRRLAKFCQDQGYMVRPIVAPTVPSGKERIRICLHAGNSFEEVTGLVGVIEAWVKSEMKANTLAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJG7</accession>
    <name>A0ABR3ZJG7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">INO80 complex subunit B-like conserved region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000739</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029523">
        <property type="entry name" value="INO80B/Ies2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006880">
        <property type="entry name" value="INO80B_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21561">
        <property type="entry name" value="INO80 COMPLEX SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21561:SF12">
        <property type="entry name" value="INO80 COMPLEX SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04795">
        <property type="entry name" value="PAPA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01406">
        <property type="entry name" value="PAPA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="INO80 complex subunit B-like conserved region" evidence="2">
        <location>
            <begin position="207"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="315" mass="35221" checksum="CCBCDB8D37A24673" modified="2025-10-08" version="1">MVESHSSSPSGKSRRGAGRGAINPYAGGDIIEGKRNRGGKKNYVVDSTEDDDDEIDAEGEDEDDHDADADGDIDMSTPVPTSRKALKPSPKGILKTTSRTQNDDDDDDDDELSDPNVETTNFGYESVDEDAEGEEDDDVDATVIGRGNGAEEDDDIDSDDDMDMSRGDPNDLSRMTKRQRARFADEDGLFMKLSDEVQVKKHFTAEELSMRRTEMARRRRNLSDKRNEEVKMETINKLLKKQPPKTNKRVKTAEEELWEAEARRPDPRMIRWVSSKVGITVSVPNQMLESPLNEAFKDTMKPSSSAPSKMIEEIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJN4</accession>
    <name>A0ABR3ZJN4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000018">
        <property type="protein sequence ID" value="KAL1899749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF1">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="707"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="137"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="462"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="533"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="557"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1310" mass="146206" checksum="58DFC37F351C69B1" modified="2025-10-08" version="1">MAPRSISSASTLSRSSLSPLPEAPPSHGPGKVPEPDISDESESDIQSQIRHSDHPPPPPAQPPLNLSDSDVEDARSAVRVSQKPSSRRASGQDSVHTVNHDNRRTPSVAPSATASAPPPSPSPSPPPPVPAPPPPADATASQAAQSMHTDPSLAEPNPPDAEPQDEARPGPPPPPSPPSPSASIIKPLQKPPAAPQSDVDASEAEIRAAKERRARKARARSQTQSHRPPSPPPEPVDGGDYGGHRSDRDERRRSERQRDRDREREIELLREARDKPRRERRGSVREKNDRERDKERDRADREKERHRGEILEDKDRAMEEDRIKGRQHRRERRNSIRTRDKDREKERARDYRDLEREEDEERSKERHRRERRGSMRARDKDREAVRAMNRERERERERERERERDREREVHGYRRHRTGTRYHDVSDRDEIPVDHRRYPARDKDRDREPDVRFAGAGAAGLAHREKDRDPDRRMSHRDREKQREKSDESDYDRDREQAIPPQIHTVQPPRTSATRPRRNSQTQPGASPQRRQSLTERIRNQWHGLRRDSSMRKSNRNKSPPMTSGGNTAAAAATAVVVATTAAAVASRPESPARAMSRPVSSSGLATAFPTMAPAPSQMGAPSAIAVESGPGVIGSGAAAAAAAAVANNPRTDPVDRLRAWLEQCDIKHGVHCSGTPPGMAPALWRPEYVIDCTEFRLVNPQAEDKYVALSYVWGEEEHSILEANKFMTMSSNLDEFCESLGSAEMSPAFLDAIWLVQKMDVRYLWIDKFCIVQDDEAMKYEHVRNMPFLYANASFTIVVGLDDVAQGLVPLDRKRVAQDSKALHMDLVLDSTWSIRAWTLQEALYSRRRVYIFQDVYSWECHCDTWQSNILVPVASGATATTYTKHKILGGSGITTRAKAAAASSLKCTARVAPAALCFRHTQWPDMDEFACIVMDYSTRRLTYVQDTQRAFSGITNLLSRTFSGGFIFGMPVMFLDAAMLWKPQASIRRRVLPPASAGPTTSGAPPSTGPIPSWSWMGWFFDDVPIDTAIWRAAADYVESTPLPKNRHLGRRYVSQFHFRLRSLVSYTLTDTAATSGQTATPLLSTGLDRRGQRLRKDTDLPIGWSFTRDNYLRHESDPATRFRYPIPVAPAVDGLDSLAGAAVQPPGSLLSFRAERAFLHVQLGSIQPMSRNGVGVFGAGATANKLLSNPPVAIGQLVLRNGRYAGTVTAHDAWLGIQSSNYDLDVVSGEKLELVAVSVSSERGGSAIFSSDVFREFARSDTLTLEFVNVLWIEWVGGIAYRRGLGHVLLAVWDGLERKDEIDVLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJP5</accession>
    <name>A0ABR3ZJP5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Low-affinity phosphate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PHO91</name>
        <name evidence="9" type="ORF">Cpir12675_000747</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01115">
        <property type="entry name" value="SLC13_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14478">
        <property type="entry name" value="SPX_PHO87_PHO90_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10283:SF92">
        <property type="entry name" value="LOW-AFFINITY PHOSPHATE TRANSPORTER PHO91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10283">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 13 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="368"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="403"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="456"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="503"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="585"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="628"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="653"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="681"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="721"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="766"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="809"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="8">
        <location>
            <begin position="1"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="97"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="131"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="838" mass="92604" checksum="CA27E465AE931ABD" modified="2025-10-08" version="1">MRFSHSIQFNAVPDWSSHYISYSNLKKLIYSLEKSTHLASGGDTESRPLISREDPEVVFTRALDVELEKISSFFVAKEGELDDEMSQALHDADNYDQEAADQLEDARNPTDNDRRRPRTGSVGSLRSQDDYAAEDSDERDSDDETTGLNKSRLSLGRRRTAPANAMHSSMHTGTDITASTEITRSWRRMSTTMDEFNERSYLYSSGILLKKRIISLYVQLCELKSYVQLNKTGFRKVLKKFDKILDKKLREPYMASTVEPAYPFRPEALAALETRIRRMEEAYAEIVTKSNIDLARKDLRSHLREHVVWERNTVWRDMIGMERRAEAASLGKTLLGPDAASRRLQGDDDKTPTRKQLRTPFGRYQLPVWLFSGTMVTLLVSIFLFAALLVIPIMEKPEQQNCLAMLVFVSVLWATEAIPLFVTSLMIPFLCVILRVVLADDGTHRRLPAKDTTAYIFSAMWTPVIMLLLGGFALAAALSKCAIDKRLATFVLSKAGTKPSTVLLANMFVAAFASMLISNVAAPVLCFSIIEPMLRTLPSDSNMSKAVIMGIALSSNIGGMLSPIASPQNVVAMGIMQPEPTWIQWFFIVIPVGIASILLIWVLLIATFNPGKNTTISPIRSVRESFTGVQWFVAIVTMCTIGLWCASKSLEPLFGDMGVIAIIPIVLFFGIGILTKEDFNNFPWTIIILAAGGLSLGKAVKSSGLLDTVAHLVSEGVEDMSLYGVLAVFSTLILIIATFISHTVAALIVLPLVYDVGIEMDTPAPNLLVMAGVLMCSAAMGLPTSGFPNMTAIMKEDATGQRYLQVKHFISRGVPSSIISLTVVLTLGYGLMKVAKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJY1</accession>
    <name>A0ABR3ZJY1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">N-alpha-acetyltransferase 30</fullName>
            <ecNumber evidence="5">2.3.1.256</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">naa30</name>
        <name evidence="5" type="ORF">Cpir12675_000953</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyltransferase family. MAK3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.256" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000013">
        <property type="protein sequence ID" value="KAL1900371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120518">
        <property type="term" value="F:protein N-terminal-methionine acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044542">
        <property type="entry name" value="NAA30-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45896">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45896:SF1">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="32"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1900371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="210" mass="23942" checksum="59D8FE8ED89B4A2C" modified="2025-10-08" version="1">MAAVDCQNLQPCFMSESKSQTPVSSSITPKYIQYSHELEKKYLPDIRALISKDLSEPYSIYVYRYFLCQWAHLCFLALNEEDETLIGVIVCKLEVHSSRSPPTRRGYIAMLAVESTYRGRGIATSLVKQAIAAMADRDADEIVLETEETNKSAIQLYERLGFIRSKKLHRYYLNGNSAYRLILLLKSVDPYGALIDAMDLQEEDSSFDML</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKL4</accession>
    <name>A0ABR3ZKL4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription factor CBF/NF-Y/archaeal histone domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_001042</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000014">
        <property type="protein sequence ID" value="KAL1900358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23645">
        <property type="entry name" value="HFD_Dpb3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050568">
        <property type="entry name" value="Transcr_DNA_Rep_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252:SF54">
        <property type="entry name" value="CHROMATIN ACCESSIBILITY COMPLEX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252">
        <property type="entry name" value="HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="3">
        <location>
            <begin position="17"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="160" mass="17502" checksum="9AEA0870A1DF8BCC" modified="2025-10-08" version="1">MADIKTIPKRKPTGQTQLPLTRVKKIIAVDPDITTCSNNAAFLITLAAELFVQHLATESHTATKLDRKPRRNIQYKDVATAVAHNDHFEFLEDIVPKTQPLRKIKEQAAATRAGINGDKNVDEVPSNRSQKQLINGSGMLGLTGLKPGHDALEDDVEMGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKP8</accession>
    <name>A0ABR3ZKP8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_000541</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF27">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00755">
        <property type="entry name" value="AFLATOXINBRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="181"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="72"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="139"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="264"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="827"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="139"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="265"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="827"/>
            <end position="840"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1126" mass="122611" checksum="EE197A36823CF459" modified="2025-10-08" version="1">MSPESPDLDSHKAFTDINTEVAAVAAYVLSQPPVDSSEYAGHMQNVALNSNSTSSTNDFTIKYDQYDTINSGLEHADNSGPVSGTAAEGASQGIHRQTPVVAASDPLRSSQALENPCPSPNTHPLEEAVADEFGLSVTATSSESTTTGSTAPKQKEDKDPAPAWSELKTKAGKERKRLPLACIACRRKKIRCSGEKPACKHCLRSRIPCVYKVTTRKAAPRTDYMAMLDKRLKRMEERIIKAVPKSDDYNPALSVARATVKPSIPGSNTSAKGASVITSQSSKKRPADEAFGHDLDSWAYAPTKSNINSSISRPPAHPLQESENDTLFAQGREALPSADIQEHLAEIYFDHVYGQAYYLLHKPSYMRKLRTGTLPPVLILSVCAISARFSTHPKLNTSPNFLRGEEWAMVARDIVTKRYEWPNITTLICLILLGLHEFGTCHGGRSWALGGQAMRMAYALQLHRDLDHDPNGDKPQLSFIDREIRRRTMWACFLMDRFNSSGTDRPMFIREESINIPLPVKERCFQLDVPASTQTLKGDIPSPKTVGDGDTSVNMGVSAYTVRVIALWGRIITYVNLGGKAGDIHPIFSPDSGYAGLSKQAEDILANLPESLCYSQENIQLHRSENMANQFIFMHIAIQQNILFLSRILLGKPPSPEAAAQTPRSFVTRVGEKAFAAASRISQLLKDADSHFVSAPFAGYCAFSSSTIHIIGIFSGNYELEASSKKNLATNVKYLSRMKRYWGMLHWMSENLKEQYRSYSDTKAKGLLTERTPASPIFQYGDWFDQYPHGVANTEFGDLTAKSKQRSDDAALEQKPDLHTVEEFFTTLTPPQSVDSSQNPAKRKASNRKGSQATPTMVTEGQQMEHFNAISAPAFNLAQPAPAPAAEDANINARLQNPSRFLPMIQTSNTTGDPHMSATSMDSSGNFMSPLGLQTAKGRQFGHSNSNPAIFSPDIFSMSLSRSANIIQPLDRQIVLDAYSTDLGMGEASKSIVDTGNSIITGENTWDAGINRAINTGQSNSMAAQTGTNSMTNFDVAVPRGQPTAVSSSNGAVSDMTWGSVGLNFGPGASSAWFMPFNTEPPELTQDIDLSITGLESFGGILAGNMSSHTDGLDGLGCNAANEENP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLH9</accession>
    <name>A0ABR3ZLH9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tuberous sclerosis 2-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TSC2</name>
        <name evidence="4" type="ORF">Cpir12675_000437</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11210">
        <property type="entry name" value="Rap/Ran-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035974">
        <property type="entry name" value="Rap/Ran-GAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000331">
        <property type="entry name" value="Rap/Ran_GAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018515">
        <property type="entry name" value="Tuberin-type_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027107">
        <property type="entry name" value="Tuberin/Ral-act_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024584">
        <property type="entry name" value="Tuberin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10063">
        <property type="entry name" value="TUBERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10063:SF0">
        <property type="entry name" value="TUBERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11864">
        <property type="entry name" value="DUF3384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02145">
        <property type="entry name" value="Rap_GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03542">
        <property type="entry name" value="Tuberin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111347">
        <property type="entry name" value="Rap/Ran-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50085">
        <property type="entry name" value="RAPGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rap-GAP" evidence="3">
        <location>
            <begin position="1369"/>
            <end position="1621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="35"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="784"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1729"/>
            <end position="1772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1752"/>
            <end position="1766"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1799" mass="197327" checksum="1B4B879F3596C319" modified="2025-10-08" version="1">MPLPSDDSPLPESSIAKPTGGLAGVFRGLTGVRLPVVRSPPQTPIEISSAPPTTASTPTSPSQSSNNVLPPPPLLSRASMSTLSTMRGLKDSQKTMLQALCSGAPSGRVEAANSLRFVLGECDIDSAMAIWYAGRDLIEPDQASDTRNAGWQLLTECVVHRDAEALHRHEFFEGIVINAHPDDFHLQLAALADLSKGGRDLSGFDYALFPLLAHWLSKCFEFVSQARKEASHARNKPKNIAAGQEQNFRQLFEFLLNVIRCNFSYADDSVICAVIDSLLKICVKTSVVDDLGNCISIFKAIVTFGAIPAERLGACVKLLGSIYSMVAALHEETWQAISIILSSHNGQAMVRHLLDVLRGFPVDGTIENDAIREVKGALSVLLKLLDKPTTNRFPQVPFSVLADGLDTTARAVRATRFTEASTAPAKIYTAIIRVINRLFDDHGDEVCIHPIAKDEDWTIVLRAAAECAKKPVNPNSSPVIMTISEATPPVTSAERASEMLNKDIATLLDRLENLAAMKKCPEFIPRQTIVRFFSNVRHILPDSAARIILEYFDEFCCCSPSDLEWENNITLVLESFFMDRERSSEIRLMALRTITDANEMNDLIIDDATSSLMPKITRNILSMAMDELDIDVLQAVMTLMTSVAITASMDMFDEIITRLGEVFENAVVVADMRGRMPFSNLTDSNSRTESVALTTSNIIVRGYVSLFLKLMDRDGEKCSRLFDVLVGIASASTLEIDARLTAMKLLFRLRADFANRIFLTHDIDCDYVAALLCRTDESRRRKLAEEANKRHPPTTRLVRGVSFNGKDIQDREDSSQGGAKGESFWPHVQIWMHPDPEALSESQISRVLVSHIPGVEPTMAPPDGMSDIDSDHETVMPSRDDADVEINVSGDDDEAPPFLEKEEDGDVEVVIDDENSLEYVSEAPSEALDITNIIDANIQDLIQEPKKIRLSLELWMEAIVDMMSLATKCDWELYSFILVHLPSQLTNHALFCDSIDQIRKLRRLLCEQTLGNSFAEPPASAGLGLRRADIAICLYQSLTMVLSYHDHFTKTEEDEIVSAFVYGIGHWERCAKPCIHALSICCHEVPQSTVRCINQMLSLMAKIITQAHVAMHILEFLCVLGRLPNIYINFREEDYNIIFGICFRYLQYVRDKRRTSQRTGAPNDLYGGLPSATAATVTVAAAALSEKDTANDLPQYVYALAYHVITFWFLALKLPDRRRYVHWIAQNLFKDADGPSGPEEQAIVTMDFMQRMSFADVDESPPNPSFKAQRFGEIEKKNWLVGNSIVTIEQAVSTGWAQITRRQPSGTNSYVLRHPFTPPPAHQTSSIGETQTKILPQYFLLQFFSSLPQPHESNWPVLLPDDEPTARTLRSFDRNLSIDGHKIGVVYIGENQTHETEILANVSGSSDYVTFVNGLGTLTRLRGANFNTQGLDREYDTDGKFAFCWRDRVTEIVFHVTTQMPTNTDADPQLINKKKHIGNDFVNIIWNDSGLPFRFDTFPSDFNYVNIVITPESRSSFIDRREQMVGSDEGEDIAAADASTAAQQTQMQHKNPFFRVKVMSKPGFPEISPAAETKMVSLRALPAFIRLVAMNASVFSLVWANRNGGEHVSSWRNRLREIKRLMERHAGNHNFGVSGPPVAPMSAGAGAGAGGSISSGMASGGAGAGSAAGAGGVIGGSYFQPPSSASAFMHESMLGTGALPRPASSMRESLNSSLRRSSVATFFTGAAGLGSPAGTAENGPVGGSSTTSGETTTGGGAAGDSGGSIGSGAPPRLAVTVEGTEMGGVEGSVLDSLDFSRWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLV2</accession>
    <name>A0ABR3ZLV2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_000631</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000008">
        <property type="protein sequence ID" value="KAL1901142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF19">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G01812)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="294"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="337"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="386"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="421"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="64"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="511" mass="57314" checksum="F97348B48EF8AFCA" modified="2025-10-08" version="1">MTRDITRTGSGDESGSGLEKPAFSQQEVSAGVIQPDIVDPDAGKSDEERALLDRKLMRKLDWTLMPWLCFLYLISFLDRTNIGNAKVAHLTKDIPMSTSRFNDTLTIFFVSYSLFEPLANVLLKRMRPSIFIPMIMFFWGCTMLGMGFIHNWEGLMASRFFLGLTEAGLFPGVSYYLSCWYKRGEFGSRLAIFFSAAAIAGSFGGLLAAAISKMDGIGGKQGWAWIFILEGLLTVIVGLLSFFFVHDFPHEAKFLTDDERARVLYRLSLDNQSSIDEKFQYKFLWQSLTDWKTYVGMLMYMGALMPMYSFSLFLPTIISSMSFTTPDSIIRNQLLSVPPYILAAANTMICGLWSDRLGRRGVFQTPLGLLAMAGFLMVMLSTSPSVQYTGTFLAAAGTYALIPISLAWVANNIEGMYKRGITMGLVVGWGNLNGIVSSNVYFDGPRFFQGHGVVLGYFSICTIFGSSLMMYMLNHENNLRREGKRDHWIAGKSEQEIAEMGDNRPDFHYII</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM75</accession>
    <name>A0ABR3ZM75_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_000610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1901244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="94" mass="10985" checksum="9FB500268F8B8C94" modified="2025-10-08" version="1">MNPRLPQKIFVTKKNLKYNGRTFKLDCIHFGFESWEDWYSFFEAPTERLDAGDNPPLNDDKEGASLQAIFTEEQEFEFMDAMDVDLVDKDDANP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM83</accession>
    <name>A0ABR3ZM83_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CBM1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_000644</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the glycosyl hydrolase 74 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000008">
        <property type="protein sequence ID" value="KAL1901155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15482">
        <property type="entry name" value="Sialidase_non-viral"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052025">
        <property type="entry name" value="Xyloglucanase_GH74"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43739:SF2">
        <property type="entry name" value="OLIGOXYLOGLUCAN-REDUCING END-SPECIFIC XYLOGLUCANASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43739">
        <property type="entry name" value="XYLOGLUCANASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110296">
        <property type="entry name" value="Oligoxyloglucan reducing end-specific cellobiohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045477739" description="CBM1 domain-containing protein" evidence="7">
        <location>
            <begin position="22"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="8">
        <location>
            <begin position="780"/>
            <end position="816"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="816" mass="85491" checksum="8334D8C3DF821339" modified="2025-10-08" version="1">MGLFKCLTALVAAAVPIQAVASDWKNVKIGGGGGFVPSVVYHPTVPGLAYARTDMGGLYRMNADDTWTVLTDGLAFDDTWNRWGIDALAVDAQDPNKVYAAVGMYTNSWDPNNGAIIRSSDKGNTWEVTELPFKVGGNMPGRGMGERLAVDPINSDVLYFGARSGKGLWKSADGGKTFAQVTSFTNTGPYAINPSDTSGYSSDPQGVTFVTFDTTSAALSGFTSRIFVGTADNSTAGASVWESKDAGETWAAVADQPTRYFPHKCRISPEENAMYLSYSDGTGPYDGSMGGVHRYDLKANTWKDITPVSGDSLYFGFGGLAVDMKKPGTIMVATLNSWTPDAQIFRSTDSGATWSTLWEITTYPERSMHFTQDFSNAPWMELFLKNDTKKIGWMIESLEIDPTDSDHWTYGTGLTLFGGRDLTKWDTELMVKIEIKADGIEEVAVLDMASIPGGTELLAALSDNDGFTYPTFADLSTSPKTMWDPKYPSSSSVDYAGTVPNTVVRTGNTAGTNQVSVSIDGGVTWTLNSASGTTAAGGSIAISADAKAMVWSTANSGVLHSDGTSTFAAVSSLPSSAVIASDKQDGTHFYAGSEGVFYVSTDAGLNFAKGAALGSATAIRSIAAHPSTAGTIYVTTDVGIFASTDFGKTFSTLGEGVLSDAHSISLGKGTSGFNIYVIAKGAAGGKVYSSSDNGATWTDVQGDIQGFGAMGGSFLAGSNNEVNVVYVGTNGRGIFYKSIGGSESSPPTSSTTPPTTGIVTGITAPTSTGVTVAATYANTTVADAYARCDGPEGNGPSACVAGYTCKKMNDYYYQCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP28</accession>
    <name>A0ABR3ZP28_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 17">Mevalonate kinase</fullName>
            <shortName evidence="17">MK</shortName>
            <ecNumber evidence="3 17">2.7.1.36</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">ERG12</name>
        <name evidence="21" type="ORF">Cpir12675_000458</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Mevalonate kinase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway. The second module is carried out in the vacuole and involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>(R)-mevalonate + ATP = (R)-5-phosphomevalonate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17065"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:36464"/>
            <dbReference type="ChEBI" id="CHEBI:58146"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.36"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:17066"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="16 17">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via mevalonate pathway; isopentenyl diphosphate from (R)-mevalonate: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 17">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 17">Belongs to the GHMP kinase family. Mevalonate kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.36" evidence="3 17"/>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004496">
        <property type="term" value="F:mevalonate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="entry name" value="GHMP kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006205">
        <property type="entry name" value="Mev_gal_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00549">
        <property type="entry name" value="mevalon_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43290">
        <property type="entry name" value="MEVALONATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43290:SF2">
        <property type="entry name" value="MEVALONATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00959">
        <property type="entry name" value="MEVGALKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="GHMP Kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 17" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 17 21" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 17" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12 17" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="17" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="14 17" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="11 17" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="13 17" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="6 17 21" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP kinase N-terminal" evidence="19">
        <location>
            <begin position="189"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP kinase C-terminal" evidence="20">
        <location>
            <begin position="361"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00029310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00029438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU363087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAL1901588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="513" mass="56345" checksum="8AAED8164F90E6AC" modified="2025-10-08" version="1">MTEYSSQTLANGSSNGATNGIANSHLTDNGVSTTTNGYINGNDALVQRLRNDRKPSSPMMPPFMVSAPGKVIVFGEHSVVYGKAAIAAAISLRSYLHVTTLSKSRRVVSLRFPDIDLTHTWKIDDLPWETFHAPEKKKFYYSLVTELDHDLVQAIQPHLEDISSDKPDEIRKIHKASASSFLYLFLSLGSQVFPGCMYTLRSTIPIGAGLGSSASIAVCLSAALLLQLRALSGPHPDQPSDEARTQVERINRWAFVAEMCIHGTPSGVDNTVSTQGKAVVFQRREGLPQIVSPLWEFPELPLLLVDTKQAKSTAHELAKVRKLKETHSKLVNTILDSMDKVTNAARDILEEDGFNEKNEDDLLRIGELMRVNHGLLVSLGVSHPRLERIRELADHQGIGWTKLTGAGGGGCSITLMKPDVSQEKLSDLYGKLEEEGYQRFETSVGCHGIGVLWPAVLKNGGEDDAWGGMEIDVDKFLKAEGTEGVEKLVGVYGQTGEREGWKFWRVREGTISQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPG6</accession>
    <name>A0ABR3ZPG6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Cpir12675_000160</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051735">
        <property type="entry name" value="CFEM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928">
        <property type="entry name" value="CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G14090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928:SF1">
        <property type="entry name" value="CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G14090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00747">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12 15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="6 15" id="KW-0349">Heme</keyword>
    <keyword evidence="10 15" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="11 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="18">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="85"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="174"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="85"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="47"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1902054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="294" mass="28570" checksum="9E940B7027F6449B" modified="2025-10-08" version="1">MAALTIGAVSAADLSTLPACGQTCVSNMLAQATTFGCSSAADTACICVAPAFSSGAKDCTAKSCEAGELPLVDTYISTMCGAVSSSSSSTSTTPGTSASASTPGADASATSALTPTTNPAAAAGASTTSEPTPVTLSSVTGAGVSTDAAKSSSIAGPGTNSTMSTSVIASATSTTSTSSTFGSGMTPTATSSTDNSNTGDSKKSSGLSSAAKAGIGIGVGAVVLAIVAIAGTFLFKRSKRPSEYNDKFSVGPMGASGSQFGYSSTHQRLSDTAGELKATRYEDMVPRAVPRNQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPJ4</accession>
    <name>A0ABR3ZPJ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribosomal protein L18e/L15P domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_000179</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08049">
        <property type="entry name" value="TAF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000039">
        <property type="entry name" value="Ribosomal_eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021132">
        <property type="entry name" value="Ribosomal_eL18/eL18-A/B/_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_uL15/eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="Ribosomal_uL15/eL18_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019473">
        <property type="entry name" value="TFIID_su8_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10934">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10934:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17135">
        <property type="entry name" value="Ribosomal_L18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10406">
        <property type="entry name" value="TAF8_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="Ribosomal proteins L15p and L18e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01106">
        <property type="entry name" value="RIBOSOMAL_L18E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Transcription factor TFIID subunit 8 C-terminal" evidence="5">
        <location>
            <begin position="150"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL15/eL18" evidence="6">
        <location>
            <begin position="266"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="416"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="424"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="436"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1902072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="446" mass="49941" checksum="324A6531F3703E66" modified="2025-10-08" version="1">MSSMDLSMVDDSDKPANPLTNTSIHLSPQAKPATPTIPSAHVVAETPQIQAHKFTPSTANLQSLIDDVHNIALSARRDKPTPNDFQVMLQSRNLPIWLLNPHRKHPIPQKLLEPTKEASDLPLPSNPALKSLPILHPDLSGETQRKAMEYIPKHFPEFPSIHTFSYTPRIEKTERDSQKIRAAAALAATQGEDALRGLVRAAKVRKQKEVRSIVQRETHGRERYRLWEAAMQKLLSDKANRPAIGGRSRLSDQEIADASMIVNATIDLKRHHVKGTHRTAAKSDNVYLKLLIKLYRFLARRTDSSFNKVILRRLFMSRTNRPPVSLSRVVANLKEDDKRTVVVVGTITDDNRLLTAPKATIAALRFTATARARIVAAGGQAITLDQLALKTPTGSNTLLLRGPKNAREAFKHFGFGPHKHKKPHVESKGRKFERARGRRRSRGFKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPJ9</accession>
    <name>A0ABR3ZPJ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pheromone alpha factor receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">STE2</name>
        <name evidence="3" type="ORF">Cpir12675_000204</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.920">
        <property type="entry name" value="Pheromone alpha factor receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000366">
        <property type="entry name" value="GPCR_STE2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027458">
        <property type="entry name" value="STE2_TM1-TM2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28009">
        <property type="entry name" value="PHEROMONE ALPHA FACTOR RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28009:SF1">
        <property type="entry name" value="PHEROMONE ALPHA FACTOR RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02116">
        <property type="entry name" value="STE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="250"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="280"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="313"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="402" mass="44331" checksum="B532A491CA61D815" modified="2025-10-08" version="1">MSNQDNSTLGSSSAFNPYTQIFNITLSDGVTQIGVSLDDMNFVVGVYYSQSISYGVQFGLCGGIFLALVTFSLPERMRKVSVRLQAAALLVNMFRTLLLALYYPSNFTELYDLASGEFLKVNDLDFFVSIGSNAAGGMTFLLIQCILMMHLWTIMQLWPPTIKCVTMAVSVLSSMALLALKIVVYVLYSQAALRIEPVSTHTGRLFFVSNVFFAANIFWFAGLFNVKLIMHLAKNKRFLPSRNKFTPIEVLVVTNGLMMVIPTIFASLQLTRMAFRFEVVPWMMTSIICVLSYGSLVAQRISNSPIQSFANIGSPSGSNGNRNNRSHSLNNHGLISTNGEPLASSSSNVESESDYGRAHMIRAGTSGSLSPTKMDIEARAVLVERDLDQQSEKRMASGREEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPK6</accession>
    <name>A0ABR3ZPK6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">RNA-splicing factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CWC25</name>
        <name evidence="11" type="ORF">Cpir12675_000292</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019339">
        <property type="entry name" value="CIR_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022209">
        <property type="entry name" value="CWC25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051376">
        <property type="entry name" value="CWC25_splicing_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16196">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16196:SF0">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWC25 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10197">
        <property type="entry name" value="Cir_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12542">
        <property type="entry name" value="CWC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01083">
        <property type="entry name" value="Cir_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="CBF1-interacting co-repressor CIR N-terminal" evidence="10">
        <location>
            <begin position="11"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="169"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="172"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="186"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="199"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1901783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="355" mass="41555" checksum="A4C4FB4210CE7833" modified="2025-10-08" version="1">MGSGDLNVKKSFHPSLMKNQARVYDEEQKALSERKKTQQRIQEIKEERAKEEVQRQLEAAGGRKRIDRVEWMYQGPNNGQAGTTEELESFLLGKRSIEKVLIGDDNAKLAKNAAQDSFLSSSSANANNARDLAAKIREDPLLAIKQQEQQVYEAMMNDPTRRRQLMSQMGATDKEKHRDGGSRSERGHKHRHRRHRSRSRDSRESSPRREDRDDGRRSDRRSRDYDRRDRDRDDKRRERRTGSSHRDNTEPRDCDKRSDDRDRRDRDYRRSGRDRRDGRSSRGGDSRRSENRSEISLDRRGGSDRHYNSAHRGGLERRSESGRSSHHRDEASVKDSRDTKRGQSLRRHSVSPERD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPQ9</accession>
    <name>A0ABR3ZPQ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="266" mass="28663" checksum="B5C6AD8D10B04963" modified="2025-10-08" version="1">MNLCRTCDQPLFIQPENDEDDDLQSGPGAASSSSAAVSAGEQVPDDLALTCECHFHWECLFDEATDIAKSGGCPACEKLLVAAKPISVEAFIQAPPSIMAVYLNEGGLDPALDLGPLLAEEAFFSINPLARRAKALHLMAIEGDVAGLLDMVRDLSSDENFATQMGPLLRFQDPLNGGRSALHLAVENSNEDVSWMLLWVASALGVEHFPQFLVSIVHELGLGRLGITSQQEDIRSLRDSNSRTPEDIAREIEFAPMLLPGVLTPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQG0</accession>
    <name>A0ABR3ZQG0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Splicing factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PRP24</name>
        <name evidence="5" type="ORF">Cpir12675_000159</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12297">
        <property type="entry name" value="RRM2_Prp24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12299">
        <property type="entry name" value="RRM4_Prp24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034398">
        <property type="entry name" value="Prp24_RRM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031766">
        <property type="entry name" value="RRM_occluded"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16842">
        <property type="entry name" value="RRM_occluded"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="657"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="733"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="824"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="949"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="528"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="589"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="812"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1015"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="528"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="538"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="589"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1015"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1049"/>
            <end position="1059"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1902053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1139" mass="126865" checksum="399A98D28089E8E4" modified="2025-10-08" version="1">MTTPVGQDNWLAYLEEASRNVEDLESCTVVLEHFRRAINAETGSLEIWRTYCEFFHSLYVSSLDPRRPGSKLARWSNDELMMAHEMFTLDATLQLWQEGYEAIRYRLSDSHILWNRWIGLEMEQLVRTQTPEGIRRITHLYRNRLVTPHAQWDQTASSFASFLSEFNRTAWESTMQQITESAQTTKAVMRGPREDFEYKLDKAQRENRHDIERAVLLEYLDWEVNHAYFHVRKNNPDCQLLHDVCTGLFSRALTGIFTRDEGVWEDYIVHLCRNMNMDKPNELSSLLNVLQRATDHCPWSGNLWSRYILAAEQAHTPFEDVERIKHAATASSKLLEGGLESLVSMYIAWCGFLKRRAVEQGGESLDHADMGFAAALEDIKIHGRKLYGNDEYKGDPMFRVERIFIEYLTEAKRNIGDARDYWNTLARKPIYADNYIFWQQYFSWEMIVYGNELLSSESLARSVPAVQRKRVPFRATAVLKRAIERRTLDWPEQLLEFYVQHCNEYETVDTIRFAQDIVRRTSKLVAKRRDREREAAYADHQTAQQAQAQTQAQAQAQAQAQAHAQAQAQAQAQAQAQAGSGVLDHQHVVPTQNNNQSSPSTGKRKRDSADDSADGYGKEAAIFDTSKRPKNDSTVAMNDGILVDGTEVKPKRDRENTTVVVSGLPGNVTVGAIKKYLREFGQIHNVLLVPEADNSTTAMVEFDSCDDARSVIMLRNGKYFGESQLTVSSGFNLTVFVTNYPPTADDGFIRDLFKGSGDILSIRWPSLKYNTHRRFCYVTFRSPEASAKAVALDGKKLENKYRLEVKYSDPANKRKRQGATSEGREVHVGNVDGDATEDELRAVFSKYGTVESVRLLRAMSGRNSGTAFVVFGTVEQAIKAAEELNNVKFRTRIIRVEVSQQRNFKTSAKTTVGLNSAADDTGTEGGLAAPSAVSEKGFPGFSAAEIDARTIALMGLPDTVNDARVKALVAPIGDIIKLVLLPAQGGAKIEFADSATAGKAQLQLSGVEFEGRKLRTGTVKDLRNEKAPGSGSKPASGDKQPLASQPGLATASKAATATKLFAPPKRTLGKGGPKRSGLAISGVKKPMGAGTTTAPVPPPVAPSPDTRADVVAGEPTKPNGTKNNADFKALFLASKKEKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFU3</accession>
    <name>A0ABR3YFU3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Hydrophobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000372">
        <property type="protein sequence ID" value="KAL1886994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1886994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="415" mass="43121" checksum="016A24848EB8E473" modified="2025-10-08" version="1">MVAVNTAVAGLINGCMIDLSVLVGLNLNTCPSIDVKLPYGLIPVSNGELWSLEKGADKRAVACPSMVTVDPFNPPQALSTEDTVNLQLVLGVLDLINVDAGLQLNLTGLLDLLVRLNINLLDLVNLDLDINVGLGRLLDSLLRLNLDISVGNLLDLNLNLGVDLNPLLNNQGGRDAPVLLGDVLNLLEPSPEKAPGVISEILGSLTPVVSGLLDTVGGLLGGLLGKRQTTDDVISMAMARRREYAYSSEASPEYDNGTGSGDQHTESNEGSTSHGATTTTTAAIVAPTVKPITSPIVKPATSNNGPTHPIDFKPNCGTCLAPSAPNVVEVEVTDLTECVNHCYLNAAGGLVNVLLDADVNVLNVVNIDLCLAVSILGTSSAGTQTCRYITGTGVGSTVPSSAYQSLAECITYEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG08</accession>
    <name>A0ABR3YG08_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uracil-regulated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">URG1</name>
        <name evidence="8" type="ORF">Cpir12675_006624</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP cyclohydrolase II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000337">
        <property type="protein sequence ID" value="KAL1887251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00641">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10990">
        <property type="entry name" value="GTP cyclohydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022163">
        <property type="entry name" value="GTP_CH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032677">
        <property type="entry name" value="GTP_cyclohydro_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000926">
        <property type="entry name" value="RibA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036144">
        <property type="entry name" value="RibA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005536">
        <property type="entry name" value="PRK07198.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47259">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47259:SF2">
        <property type="entry name" value="URACIL-REGULATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12471">
        <property type="entry name" value="GTP_CH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00925">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142695">
        <property type="entry name" value="RibA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP cyclohydrolase N-terminal" evidence="7">
        <location>
            <begin position="34"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="GTP cyclohydrolase II" evidence="6">
        <location>
            <begin position="267"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1887251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="450" mass="49725" checksum="6BC721BA998078AB" modified="2025-10-08" version="1">MTMDTTNTTDEPVAEQNAAATTTTTQPKNQYASRIILTTYPGQSVVDPIPLKWGCADPLERGPVLVSRSGKTLTRRNAIGAHGGSYSVYNALAIAAGDLPPDFRPSFTNTQPSFDFPFQAAWGDVTKIVSMDPFGHDVTRNYKKYLDDGLDVRPTIAVTRANMRVAEIVDSIRAGRLQVDGNIITNAEGDVRVTKAAVEPVWYLPGIASRFGIDEGTLRRALFEHMGGSYPELVTRPDIKVFLPPIGGLTVYIFGPPERVSNPSCRLALRVHDECNGSDVFQSDICTCRPYLAFGIEEAIKEAQNGGSGLVIYFRKEGRALGEVVKYLVYNARKRGGDTADKYFQRTENVAGVRDMRFQALMPDILHWLGITKIDRMLSMSNMKHDAIVEQGIPILERVPIPDEMIPSDSRVEIDAKINAGYFTTGKVYNTEDLKTVQGRGWASWEDVTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGY0</accession>
    <name>A0ABR3YGY0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_006482</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000308">
        <property type="protein sequence ID" value="KAL1887589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF9">
        <property type="entry name" value="MEAB PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="5">
        <location>
            <begin position="67"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="182"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="308"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="86"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="259"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="308"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="318"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="330"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="342"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="417" mass="45625" checksum="574F67870820765B" modified="2025-10-08" version="1">MSITKHNKEKLKVKEDTGGEESMESTPEAEQATASTTTPSSVSNAQEVQQPKRKGGRKPIYATSEERKQRNRQAQAAFRERRTEYIKQLEETIRVHESNLQNLQAAHRTAADECLMLRYKNSLLERILLEKGIDVQAELRAKTGSPNLGPTHMPQNMVQPPPIQRAIMNRHNQNRRPASIATKLDTTPISPLPPPLHQGGLGALPSPRSRPVPSSNHSNSPTAPALTFGGPAALSPAASDYMSSRTSVPPSIKPPHMSPINSMPAPSQVMATHQQSHAQSRATQQAPYYPTPGFQSHIEQLEQEYDAQTEMMDDSELEPSSGNGGYSTYSAAPSIMPSPASTRGSHAQSQSEAMQPQQQQPQQPQPQSQQPQQPGANGGQYPSMNQLLDSGMEWDPFGLSASMAFPTPFAFDQSNMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH02</accession>
    <name>A0ABR3YH02_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Uracil catabolism protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_006623</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000337">
        <property type="protein sequence ID" value="KAL1887250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012469">
        <property type="entry name" value="DUF1688"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31687">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31687:SF3">
        <property type="entry name" value="PROTEIN URG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07958">
        <property type="entry name" value="DUF1688"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1887250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="429" mass="46727" checksum="161A7A6E0D431B5B" modified="2025-10-08" version="1">MADSDVVNYLTSLKAVRDRSRVVFEAAKVGSLTNFEYHADKLPAAADFVISVIERDFGPDKFNTIPPHGRWQHFNVGSVDRITPLLEKWEAAGCDKLELTRRLIDLFVISVLLDAGAGDVWTFKETDSGNVYNRSEGIAVASLHMFLDGALSSNKSPTVDAKGLIALTDDVFNKHFQITPENPMVGISSRVQLLNSVGKSIQANASIFGESARPGGMVDHLVAASGDSKTLDYEILWSTLQKLLLPAWPSNRTQINGVPIGDAWPLAVLERALPAGPVGSHIQPFHKLTQWLGYSLTVPFVRVLGFSTKNTELGTGLPEYRNGGLFVDMGVLTLKDEIKKSGLEASSTPGLPLYDATGDVIVEWRALTLALLDELYVIARESFQARGVELSMAQMLEAGTWKGGRELAAKYRPETKSSPILIDGDGTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH82</accession>
    <name>A0ABR3YH82_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_006658</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000343">
        <property type="protein sequence ID" value="KAL1887188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF2">
        <property type="entry name" value="ARYL-ALCOHOL DEHYDROGENASE AAD10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="3">
        <location>
            <begin position="36"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="390" mass="43504" checksum="AF5143BBBD7F7614" modified="2025-10-08" version="1">MSSQNESPFFGAVAPPPTELGCLRIMSANCSLRVSPLQLGAMSIGDAWKEFMGSMDKESSFKLLDAYVAAGGNVIDTASGYQNDQSEQWIGEWMKERGNRDKMIIATKFTMDYQAYRFGRGKTPNTSGNGRRSILLTLRDSLKKLQTDFVEIFYLHYWDFTTSIKEIMDTLHALVESGKVMFLAISDTPAWIVAAANTYAIENGKTPFSIYQGRWNIGARDVEREIVPVVRHFGMSFCAWDVMGGGQWQTKKQIEERRKNNEKMRSTFSNGIDQSPQDAAISEALEKVAAEVNAPNIQAVALAYLLAKGEQLKINVFPIIGGRKIEHLNGNISALSINLSDKQIEYLESVAPFKPEFPYSIFGSDPNIDPNGAIMLKQTGSYKFPLPFRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHF8</accession>
    <name>A0ABR3YHF8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ADP-ribosylation factor GTPase activating protein, ER-Golgi transport</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">GLO3</name>
        <name evidence="8" type="ORF">Cpir12675_006474</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000306">
        <property type="protein sequence ID" value="KAL1887628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08831">
        <property type="entry name" value="ArfGap_ArfGap2_3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45686:SF4">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45686">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="7">
        <location>
            <begin position="11"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="142"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="279"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="142"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="279"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="290"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="309"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1887628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="477" mass="50888" checksum="21F31ED4D495ACA1" modified="2025-10-08" version="1">MSALASKQQSMKIFEKLKTKPANKICFDCSQKNPTWTSVPFGIYLCLDCSANHRNLGVHISFVRSTNLDQWQWDQLRMMKVGGNESATKFFQQNGGSAALNSKDPKTKYHSAAASKYKDELKRRAARDAKEFPSEVVLDADADAETPSTEADDDFFSSWDKPTIKKPTPPISRTNTPPIISRTASPMNRTGSPLAKPDSEAPKPAARVTTSAALRKTGPAPRKNVLGAKKVATKLGAKKVVSADTIDFDEAEKKAKEEAERIAKLGYDPEAEDAAIEAAAAKSTKTEASNVLSPTPTSPSRGGFGSTSTREKSTADTERLGMGIARLGFGQVGMKAGAGGSSAAAKKGTGGFGSVGPIKAKQVDDSDDFARKKFGTQKGISSDEFFGKGAYDPSAQSEAKSRLQGFEGATAISSNAYFGRPEDEEDMAEDYGDLENVAKDFIRQFGITAGDDLETLTSALGDGAVKLQGAIRQYLGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHJ0</accession>
    <name>A0ABR3YHJ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Endothelin-converting enzyme 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_006540</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000318">
        <property type="protein sequence ID" value="KAL1887445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08662">
        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="entry name" value="Neutral endopeptidase , domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733:SF167">
        <property type="entry name" value="FI17812P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00786">
        <property type="entry name" value="NEPRILYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045287085" description="Endothelin-converting enzyme 1" evidence="8">
        <location>
            <begin position="19"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 N-terminal" evidence="10">
        <location>
            <begin position="65"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 C-terminal" evidence="9">
        <location>
            <begin position="500"/>
            <end position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1887445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="704" mass="79339" checksum="10278BCAD499FD06" modified="2025-10-08" version="1">MKFGSILTPGLLAHAVNAQTSPSPAGDEAVSASKPDSEYCTTPACLRIAEEFRSNLAPSYADIDPCNNFEELACGGWRLKHDFQTDHSKVNTISLIENRMVEVTRQVVEGPLPSSIDPNSQDAKNFYKMKAIYNACMDVDTINNLGIEPLKKVLAEIDNTNTIKDALLILLKHDTSGLALIGPQIDDKNPDAVSIGITGPTNLGMPSREYFELEAVSNRYYEIMTEVFSKLYPKTTSQTLKDLYKLDRNIAFSMPTKLELQDVESLYQGMTMEEANELVPELGVRDIINALTPEGVDTPRIIVHHPKYFSELRKLLSEASPDVLKAYFRWRLIVSYEPFIEHQSLQPLKEFNENIFPESEREAHCVDHINNSVDGIMNRFFIEKAFSPEAKDMADKLVADLKSTYIEKLKTVDWMDDQSSGRAVKKLLNMDEKIAYSTLSPNITNPDDLAHMYRHSVVDDTTHFDNEVSLRQMRLKIQWGAVGKPTDRNEWQYSPNDASTYYQIGGNELILPAGLMQFPIFDTETPAYITYGGYGSMVGNEMTHAFDSVGHRFDENGAYSETTSWWTPETTNAFNKQAQCFVDQYSKFNLPGTSNDELTYNVNGELTKDENMADAAGISIAYQSWKKLNSGKDKKLLGLQFNPDQLFFLSFANARCSKDRTPPNRSARQSYAPFWARVSGTLANSEDFLKAFDCPVKEPTCKIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI56</accession>
    <name>A0ABR3YI56_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">V-type proton ATPase subunit H</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">VMA13</name>
        <name evidence="7" type="ORF">Cpir12675_006326</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the V-ATPase H subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000283">
        <property type="protein sequence ID" value="KAL1888009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.150">
        <property type="entry name" value="V-type ATPase, subunit H, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004908">
        <property type="entry name" value="ATPase_V1-cplx_hsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011987">
        <property type="entry name" value="ATPase_V1-cplx_hsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038497">
        <property type="entry name" value="ATPase_V1-cplx_hsu_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10698">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10698:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11698">
        <property type="entry name" value="V-ATPase_H_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03224">
        <property type="entry name" value="V-ATPase_H_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF032184">
        <property type="entry name" value="ATPase_V1_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase V1 complex subunit H C-terminal" evidence="6">
        <location>
            <begin position="360"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR032184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="481" mass="53474" checksum="5ED196560DB7E1C6" modified="2025-10-08" version="1">MLIDPSAYLATLQNNIRQRPIAWDGAVRASSITDAQLGKIRALSSTQKSEDRRKTIENDMNGFAELFLGAPGKLSSLESAAKHANIIQHLLVLFGDILELVPNFAFSLFKAGNPCPTLLGLLAHSNNSEDTIPLLASTVLTTIIASTRDQSAITLKDALPVLLTYLSGLAKNQDSGLQAVAVQQYSSLLYGQAPRREFWAHRSETVEPLINILRTAAGVGANGNSSVSMWSGVSSGRSAGVDNFINGGVGLQLLYHVLLVLWQLSFEAEEIGDDLDDEYDIIVLYTQLLKVSPKEKTTRLLIATLNNLLEKNPKSLLPIAVLARLPSQVETMISRHMTDPDLVEDLTSLKEMLEEYSKNKTTFDEYMAEVESGHLRWSPPHRNTVFWAENSRRILEHNQGEIVQKLAEIMKKPWDNDKQVLAIACNDVSFLVKEVPEKRHQLDKLGIKTRIMELMGEANETVRWESLRALGGWLKYSFDSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIC5</accession>
    <name>A0ABR3YIC5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006307</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000279">
        <property type="protein sequence ID" value="KAL1888085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="214" mass="23987" checksum="3122316F2EE26FFA" modified="2025-10-08" version="1">MVQPSDAEFAAILASPYPKAALGELYGTITRNSISSGKHLPFLVPTTFIGCFVIPPLYLAIPQRGRPWLRSLRWAVLAFVVAFNADIFLRSASTNVACGYGIGMVAVWGTMVAAMALVFLDAQDLERVAKRTRPRALTRAQKRARTTKSPRRGKKLAQNRQDKLLTAEMVEEEVEYYWESYPYSGSFGQRFLWGFDIVTSIRGAGKSNLVRFWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIC8</accession>
    <name>A0ABR3YIC8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">COG4</name>
        <name evidence="11" type="ORF">Cpir12675_006303</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000279">
        <property type="protein sequence ID" value="KAL1888081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048682">
        <property type="entry name" value="COG4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048684">
        <property type="entry name" value="COG4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013167">
        <property type="entry name" value="COG4_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048680">
        <property type="entry name" value="COG4_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24016">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24016:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20662">
        <property type="entry name" value="COG4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08318">
        <property type="entry name" value="COG4_m"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20663">
        <property type="entry name" value="COG4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00762">
        <property type="entry name" value="Cog4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="COG4 transport protein middle alpha-helical bundle" evidence="10">
        <location>
            <begin position="188"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1888081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="833" mass="90849" checksum="EF2428D29AE4A49A" modified="2025-10-08" version="1">MTTSIRPPPTPGLRSSAAKPDSKVLPSIHNASDISAVRTALANLQQRDVALTAKLDGLVASQAELARELTRLDFLRATLGSQAIAVRTISSQMVASAAETAGRLSDKVRELDLEKSRVEATLGVVEQVAELKACVNGVVGSMGAPQDWEAAAGYIARAARVPETIVRGGFATAIVPSVEVPDAPWTTLENAKESLCGLFLREFEKAADEGDAAKVTRFFKLFPLIGRGDTGLDIYGKYVCQGVSGTARTTLRQATDAQKTEGLFYANALTKLFEHIAQVVDGHGGLVERHYGNGKMVRVIERLQQEVDVQGGIILDSWSEDRNIERRLKDIKSYPFSFLVQSFLPQQQRNSAPRVGSPAMGSAANARDSEDEGVNMKGVDALLGEISVMLSRWALYTRFLSAKSKDPTALDDASLVLPDVLVKSNINRKIASKLTTPYNIMSTFFFRRSVEKAFQMDEYPTGLTLNASKTLGSSPPFIIMAVDDIVFIVNAVIEKCLLTSQKDIVASVIPTVARILGADFVGMIQRKMRDESYPKPLVQGGFPPEDKIISFTVLINSLDMANDYLGRIVAGKTGTTPEQAMAAASALGSGSATTLTSGSSSAALIPAPSSQVSHSFPFVKDAAFAAGHLTNMLHSFTSKTTELVLEGIQVLFSNVVKLRLRPILSETFRDVDYSLSEEDLEEISQQDGQDVMELLDQVPRRFEHGWDLLVRPIARIMTPKTYAELHEITARYLARMLEKRIWSYAGRTVGFGAIRMEKDFGAIISTVAKGNYSVREAFSKVSQILMVANMEEEEWEEMAIAAQAEVEADAGNEDGFLWVLSDEERNKARTLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIY0</accession>
    <name>A0ABR3YIY0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006273</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000275">
        <property type="protein sequence ID" value="KAL1888167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="39"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="69" mass="7838" checksum="AC232FB9934B1E17" modified="2025-10-08" version="1">MKMSLRQLNDHGPNGVAMPISTDLGLLENNTDEELAQKLHTLKTEHDSLFREIRKLEERLVLLQKASLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ08</accession>
    <name>A0ABR3YJ08_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006387</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000292">
        <property type="protein sequence ID" value="KAL1887862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="68"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="140"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="324"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="638"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="705"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="538"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="74"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="149"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="329"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="380"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="393"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="418"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="437"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="705"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="732"/>
            <end position="781"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="825" mass="90849" checksum="3643D5B36E3D78AC" modified="2025-10-08" version="1">MSLATRLTTRHPLEQDTTGISRCLRLPEPEARTEIILSDQSQLARSTPKLHITSLPASLPVVAHQAHSIAHRQQPAQAQAFNSPASPSASTPLRNFRTLQPSPKFYENSSLSVPGSPTPSSHALRHTPVHREGLSSFASRSANHRSLDKGSSSCSRIHSQVLSDSDSDSDEALTVPEFPSPDKHVTASDNLGGRLSTAHRHKHYRSALLFALEEALRSPYSFTPDPVEEEARLTEPYGIQIPLPENPHTSVSVVVPEAKPVFRAHRRVKSQPLVPPSASRSAFIRQTPKPLTAVETMSSRHKTTVSSSTAPAVSAFAAAAGIKSPTQIMKERQDRERRRAEQKEQDSMMRDQEKRRRSTAEHELRLQEEARRRSAERKATTASATAAAGGATYQSPNSHTKSYMSASAAQPATPRSRIAQNPATTNINMDASPDAGPSSQAPPNSSGSGKRQSTSQSKSSFPHAFERWEALSAQWEGVTRHWIRRLEMNGTMLETDPLSKTYSRQVTDLSAAGANLFHAVVELQRLRASSERKFQRWFFETRGELERIQEEKAQLEAALRDEQNARREKATQAQNTETVNILQRQLAEMKKELTISKEEARRAWEELGRREQEERERTFSLQNGQPTIVGGVQVVPMSAGNSRRGHMTQAQAQQQQQNEQVTGSYTPPHQPPTATAAANPEYPVEADSHYHSGYVLDAAGNRLLDSQGQPIPYETSGSPLSHPDMDDYNLPSSSRTHQDSSQSQQQYQAMTSATMGSSSAMMQPSASPASFSAPQTSTSQPVSTADNPYSGASWDIPTTHHHLTRLSDVLEEEESRTTASQISRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK64</accession>
    <name>A0ABR3YK64_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endoplasmic reticulum lectin</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Protein OS-9 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">YOS9</name>
        <name evidence="10" type="ORF">Cpir12675_006076</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Peripheral membrane protein</topology>
            <orientation evidence="1 7">Lumenal side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the OS-9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000249">
        <property type="protein sequence ID" value="KAL1888711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.130.10">
        <property type="entry name" value="Mannose-6-phosphate receptor binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009011">
        <property type="entry name" value="Man6P_isomerase_rcpt-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044865">
        <property type="entry name" value="MRH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045149">
        <property type="entry name" value="OS-9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012913">
        <property type="entry name" value="OS9-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15414:SF0">
        <property type="entry name" value="ENDOPLASMIC RETICULUM LECTIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15414">
        <property type="entry name" value="OS-9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07915">
        <property type="entry name" value="PRKCSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50911">
        <property type="entry name" value="Mannose 6-phosphate receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51914">
        <property type="entry name" value="MRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 7" id="KW-0430">Lectin</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="MRH" evidence="9">
        <location>
            <begin position="126"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="39"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="484"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="485"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU369099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1888711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="518" mass="58494" checksum="38A5AD5F259B1836" modified="2025-10-08" version="1">MLFEVVFDDAYILPRDAEALLTKQVDSVAAAVAGSPPIASEAGESSDIVPSGANKNTEDSDAQNTEPNETYEFMDIYPGKYLCSIPIIQPKPAENATATALALENEKKELARALEDGWKILKSMDGECLFFMSGWWSYKYCYDSYIVQFHALASGPGQAPPVPDPKMAAYVLGRSSKSHNEDGNWLDEEWQKGADDVKSSTTDMQVKGDQRFLVHRLTGGTMCDLTHRERTIEIQYHCAPGASHDSIAWIKEVTTCAYLMVINTPRLCKDAAFLPQKEAAANFINCREIAPKGLSPEEADAWFAQRKHEEANMEDHTMAGDINVKIFSPHDDGQNFVEEHRMELMIEFDQEEIKNLSPEEIIAMAQKRAEEILASSRENDHKNVKDKYSDTTWSIIQDGTAGDAPSDDMFLRDIMQALSNIISHEMVVMSAKRLRREVEETLATYKEFEAKLPERKTPEWLKEHILILEEALRQDDQFGIFEQYQKTREGRGRAQEPNAPNGDNEGSQEEFFVRKDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK69</accession>
    <name>A0ABR3YK69_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Forkhead transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">HCM1</name>
        <name evidence="8" type="ORF">Cpir12675_006270</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000274">
        <property type="protein sequence ID" value="KAL1888176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00059">
        <property type="entry name" value="FH_FOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045912">
        <property type="entry name" value="FOXJ2/3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030456">
        <property type="entry name" value="TF_fork_head_CS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46078:SF2">
        <property type="entry name" value="FORK-HEAD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46078">
        <property type="entry name" value="FORKHEAD BOX PROTEIN J2 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00053">
        <property type="entry name" value="FORKHEAD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00658">
        <property type="entry name" value="FORK_HEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Fork-head" evidence="7">
        <location>
            <begin position="239"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="5">
        <location>
            <begin position="239"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="32"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="327"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="397"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="514"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="697"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="774"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="32"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="353"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="428"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="445"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="712"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="775"/>
            <end position="793"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="802" mass="87953" checksum="0F5618A5464F1818" modified="2025-10-08" version="1">MATQPHTTPDLSRMFNTNENFMFDNMMPVSRNITTSSHAPMSTGHTSNVHSHQQLQPSHSISQQSGSMNTKSRRPLQNASTNSILMPPLACDNTAKLPPHKNRSVDNLSVAKRLNGQPLQSMAMAPPPAKGLVTDELKKKPFLSKFKTVAQKPSHLFTDPSLTFTGKENMHPSLYQSPISTNMDVFSPTTKGNGKRALMEAAPIKDSRPNKKTKQTQDDEPVEIPAWDAFPPIMDDGQKPGHSYAQLIGMAILRSPNRRLTLAQIYKWISDTYSFYPPNDAGWQNSIRHNLSLNKAFSKMERGKDDPGKGNYWYIVEGMENQFVKEKPVRKTSSAAENIPIMSSRLEVPQSAKAPSTRPQLHTMSSHQLPQQPEATLPMLLASQSQPAPAVDISSDATIPISDLPGQEENADRHDNDSALDSLLYSPLPTTVHSSPPVTRHYNAGNGTPPSLRTMCSSVDQSRKKLTSVDDSGYISSLDSSVMRQSKILPTDSERPRHKRGRAEEEIARIRASSYESPTKNRSASNFVPPSSSPMRHNTALLHPLTPAMKFKASIKPPASVSPNTNLRMHRDKVQSMLQSPLRKMTGIFGENTPWSPAFKLEESAYLNDTMIENTNFDIFQEMANDDFFSGLPNIEQGSPIKRLVKRVRLERTQSLLDTPGPKIWEDGVPACLDTPSRAFEGLSSPTKHLMGSPLKASALNSTIPPPPKITVSGSSKTDTSNPATTTAPPSIQAPQLPWAALSYNPALRLDEPAEVSGLDMLQGFQKLGSGEALSGTTATKGTSSNISATSKPAPSRFFPMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL04</accession>
    <name>A0ABR3YL04_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Spindle pole body protein pcp1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_006151</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000258">
        <property type="protein sequence ID" value="KAL1888510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012943">
        <property type="entry name" value="Cnn_1N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019528">
        <property type="entry name" value="PACT_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43941">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43941:SF1">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07989">
        <property type="entry name" value="Cnn_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10495">
        <property type="entry name" value="PACT_coil_coil"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Centrosomin N-terminal motif 1" evidence="8">
        <location>
            <begin position="178"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Pericentrin/AKAP-450 centrosomal targeting" evidence="9">
        <location>
            <begin position="1441"/>
            <end position="1535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="152"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="373"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="449"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1212"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="852"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="987"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1377"/>
            <end position="1423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="385"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="411"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1212"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1222"/>
            <end position="1231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1250"/>
            <end position="1270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1888510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1579" mass="180019" checksum="65AF24384F9F0601" modified="2025-10-08" version="1">MVYPGYGDILDTPRTNLGDATYLSQHQPDLDISQEASFVSPTRDDAQQNLFAQLRGGRSGATIRTPRRGPLADRRNIPDNGPEFTPLLKSATRNGGFRRRGKENGNDMPGTPTGLLDRIEEDLTPIPAFENSLLGRSVMSIGTPLPADASSVASTPLNLPPRRNFSGKGPLDDGNQMSLREQENVIDKIEKENFGLKLKIHFLEEALRKAGPGFSEAALKENTELKVDKVTMQRDLQRYKKHLNVAEKDLEQYRQQMIELQERSKRKYADDSLKAEAERLRQNLEDKESEIDRLQAQLEQAESGSAEGDKLRDEITDLEAELREKERLIAEHQDKMEDLREKLDNNAEEKVQGVLQAKDEELGDLQQNLQDRERALDEKEDEVEELQRHLREKEQSLDQKEDEVTELQQAVRDKQRQLEEKDGQVSELRLKASRLADREAEIEKLKESLRQARFSSEESDNLQEKTRQLENLNADRKAEIDGLREKLRRAKEQEIETEQLRVKVRALETRDMEVAELEQRLIAVEARSKNEQRQITELETRSKTDQRRLVELEEQVQDAAKTSDDLEFARDTIEDLERKIRDIESESDDIRIKMEEALVERERAEADLEELQEEMANKSTMSKSLSRQIDEKAARLQMELEQAGKDFSALEKQYATALAEGEELRTKAREAKRERDTFERDLHTLKAKYTDLEAEVEGLKDQKLHLQSQHDNLAQESASLQKEAVKLRKLVSDLETSLSREREKALDLDRDARDLYASDIDRLNEEIFKLQAEIHERDNLYDTDSDKWENEKRALEIARDRAEQKATDLQRAVENLRQAGDTLSSKETRLLDAIKDEADRHSRDEVVLSRRIEELQHALEIKQSSLSELRTEMSKVREELRHAQSRARTDAEKAEALADEVEVLQAVMEEDAENATREKEDLMAQIETLRVANRAASLGSHDEVSRQTSLTLERLRTQLSESSLNFSRVSKEKMALQEQVATISLELKTIRESIAEVRAERDELEAELKSFSRQRGEETYRIDQERVDLRAARTKLEAEVARLSEEKELLERRRAEAERSLEDEIERAAEDENKLAQEISKLRQASSSSGAHDLQELSAARRAIRVLERQLDEYQAKLAAATTPDVSGGEGSSEILAIRQDLLAARQKELDYLSRESSNKEVVRGLKKRIAQLERSLHEAEMSKLLNSPMSVASSPGSSSHHAEIELLRKQVTSAQQSLQESKAKLREAGHKATQSAAELRSQLADVEDERAALEESLDEARREADDLRAEHERESRKLALCLEKAEKEAASAVARAEEIIQRNERDSHSSQEAKALKRQLTKALAESDALEHDVRMQFATIESLIASESSLRKKLERTRSERAAFRAGAEKLARDFKALQASADDRECTIQELRQELAQAAADDSRTTIAALTADIQAAEEKHRKELRGLVMQMEWMQARWEREAGMRVDAAFAKRFLQLQLDMANACNTAQLRQLEHIRRDVLGDKTALTLPSSALKSLSPTSATSLSSRPTLKTVALAVRFVTRVHRGAALWQKQEATRAKIVEAVEDMKKKKRVRDLRSSIVTGTRRQGGGLARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLE5</accession>
    <name>A0ABR3YLE5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Polynucleotide 5'-hydroxyl-kinase GRC3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Polynucleotide 5'-hydroxyl-kinase grc3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">GRC3</name>
        <name evidence="11" type="ORF">Cpir12675_005886</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Polynucleotide 5'-kinase involved in rRNA processing.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Clp1 family. NOL9/GRC3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000227">
        <property type="protein sequence ID" value="KAL1889176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045116">
        <property type="entry name" value="Clp1/Grc3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032319">
        <property type="entry name" value="CLP1_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12755">
        <property type="entry name" value="CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12755:SF3">
        <property type="entry name" value="POLYNUCLEOTIDE 5'-HYDROXYL-KINASE NOL9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16575">
        <property type="entry name" value="CLP1_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Clp1 P-loop" evidence="10">
        <location>
            <begin position="301"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="27"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="706"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="744"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1889176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="768" mass="83740" checksum="0A1B21A785665C8D" modified="2025-10-08" version="1">MSTPSKKRKVAASGQQATTSAFCALAARRHQSTASPAISAAAMLRSRREQQSQAQTEVNDLPRSPGKKAGRTTAQPDNGPGIATKIKEKKPARRGRRSDGTTDDMSVSKSLKAANDKEEISANVHEHISVLGRSPARQSGPLLQMSSLVQTPKNWSIKSGVVSLNLENDERLVIVGSYGIKIHRGEVTIAGATLQSSDMTYWICAPLCHAVPVLRCYKGARIDLYPDPVFRNMRQLESLSHLFREIWPSNMSQSFRVLFTPEDVPKRTTVQLLTSPPEWNKKLAEIASSDIAKNPIYFICGPKGAGKSTFTRLLGNKLISTQLHGFYTSSRKTTIRGVNIVDIDPGQAEYTPPGLLSLIHTKNLNTAPPFGHPWTDAAMATEMVHSHAFGALTPGADPDLYLSLAIDLCSRAKGAPTLINTPGWTLGTGLNLLMSLISRVHPTEIIYMSEGGPAETIEGLRSVSRKNFYTLPSQSSDPAPRTSAQLRAMQTMSYFHWRPSSTDNMRPIWVPEPLSEVTPLVAKYRGQKRGIMGILSYGAQTPPFLLAESLNGMMVAVVRIQDPKAFAAFQTARTLVDVGEMEVDEPGLVPTDAKYDEVVISSSPEGLPIIANPDNVSLDSQYSCTIGLALVRGIDTTSAALQLLTPIPLDTIRNLRENGQRLVLLHGQFDAPTWAYTEDIYRRSLALNRVSVEGEKMQDSVNVEYGSDNESEASAITVTSDDEKGRAADSATGEAIPWVQVIHGDQRRPQGSRAWRVRRDLGRGNGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLT3</accession>
    <name>A0ABR3YLT3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Mediator of RNA polymerase II transcription subunit 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Mediator complex subunit 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_005848</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the Mediator complex subunit 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000222">
        <property type="protein sequence ID" value="KAL1889299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019680">
        <property type="entry name" value="Mediator_Med1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35041">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35041:SF4">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10744">
        <property type="entry name" value="Med1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0010">Activator</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Mediator complex subunit Med1" evidence="8">
        <location>
            <begin position="2"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1889299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="577" mass="63573" checksum="DE56D1EBC97EF085" modified="2025-10-08" version="1">MGLVHLWEGSTNGPKPRCITMAGKMFSVEVNLRNNIVVDVQLLFDESAEIVKQQSPRGAEILKQDLQLEPYQSPLTKTLDQFAANLERLHGQDKLSVVPGFDCQEALASMSLSLHKLYDWDLEKARMELAPSSSEEAIVNAVMCTRHGRPHLHARGSVGLSLQYWKEKRLAPAKPAIAKVVEDTELVWSLLIMCAKAPMGTMPFALARVSMEWIAPDIAKPNPMAEETLQSLTGVVLDWQHPNNTVLPDETGMGPKYPDIVFKATLDPPVVLPQSVFVQVMQAIGQAPMDHQAPSSTFDALFFPTQSPSSAAGSSIITYDPSEPRKISSKRKIRRLDNGGGESTALVDTALFVYKPVYGQVLQEIQFAHPQQIIELLPVLRQYAFVATLLRNSFPLVSSQSLYTHGADDGVRYGNTSRALTHKQLYTSMVNRLDTPPTPTPGEPIVITPNVPDPINASIDGRIDASLSLTPVPRLQIIFLVGHNKATVKNEFNKVEDDNATATTIDAGKQEMHERAGTLTLEIRLSGDVHVISQNIITAEAQAAGRDPQVLGKALMVMEDLCSWCEWIRSRFDLSHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMC0</accession>
    <name>A0ABR3YMC0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_005855</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CENP-O/MCM21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000223">
        <property type="protein sequence ID" value="KAL1889289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018464">
        <property type="entry name" value="CENP-O"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09496">
        <property type="entry name" value="CENP-O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0137">Centromere</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="10"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="138" mass="15324" checksum="7ADB98C5A84A5AE2" modified="2025-10-08" version="1">MSETQADSISQSLDAEIEALHAQVANLKQQLRIQATNLLTSESIHRALLSLPSPSTASSQADHSTDLNPVSKVLATHFAEQQTYDQQSLYRICASITSFQVLDPDPHAVDHGKVFGLRFEVMTCEKLLEYPKIKRFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMT7</accession>
    <name>A0ABR3YMT7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000209">
        <property type="protein sequence ID" value="KAL1889621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="403" mass="44645" checksum="AFF023A6EED1EC2B" modified="2025-10-08" version="1">MRSTASLSKIFPSIHQPLPLTVHQSHRLLDALKASFRANLDREHGQLSQHQKDSASSVSGSGSRSTSTDSIIDTQVRRPTDDHVRAILSNPVFRQPSATLSETTSPKKLGPMEVFDRAVAKDMMTFKAASGCMRATYIEVSQSSAPCISSALASADVSRRMIPWLQSIGFEKDFSFVLNPRFTPMLVRFIVAEKNDAIIWSWISKLMAHDEITAASTKARALLSYLIKAKVQLGTTAGYNLDGAFASILQADKLFHDHVYYQHVLWAPWRSLSWSATVNAWERPQPSEDMFDNYLRVLQRFATPSPIDEAHLSIHHPTHPEHEKAATFLTGYGLAQKQRNSLDDLEKSAKDPNAVRVFLMAMDTVRFLTQLGKSSDAHNILESLGLQSFGLKGIGADKGPEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNP6</accession>
    <name>A0ABR3YNP6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alpha-actinin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ain1</name>
        <name evidence="8" type="ORF">Cpir12675_005616</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the alpha-actinin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000202">
        <property type="protein sequence ID" value="KAL1889848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21215">
        <property type="entry name" value="CH_SpAIN1-like_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21291">
        <property type="entry name" value="CH_SpAIN1-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001589">
        <property type="entry name" value="Actinin_actin-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014837">
        <property type="entry name" value="EF-hand_Ca_insen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11915">
        <property type="entry name" value="SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08726">
        <property type="entry name" value="EFhand_Ca_insen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01184">
        <property type="entry name" value="efhand_Ca_insen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46966">
        <property type="entry name" value="Spectrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00019">
        <property type="entry name" value="ACTININ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00020">
        <property type="entry name" value="ACTININ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="6">
        <location>
            <begin position="542"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="6">
        <location>
            <begin position="656"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="1016"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="95"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="170"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="473"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1162"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="105"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="199"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="365"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="482"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="502"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1192" mass="129090" checksum="3355206EC9295892" modified="2025-10-08" version="1">MAARFFSRLIRGDDSTGATTEATTGVAGATEAAGVPGTIATSGGSPGNSLLAVGASSGGEHDEDSDEVLLEITDVTHGRANTAAITTKIIVGKTASRNTDASTVSKASSDASAGADANRLGDKATQDADSSFCLLPDQGFVSEPLDSQNPPPLDKAHQNHQINTKDSLVAAKPPACSPPTSLPVSPQASSPPSSPPSPSSSSPSSSSPSSPSLLALEALGSKEDQIDDTQTLDQTLAKSPFRTATLTIAPSGTAPVAVPTTTAAAAAATATVAAVTVIAVDASDQTPEISPNLQALVHHQTPPSTTTTTSRVQVSTNSLVFLNDSRASISSSACSEISTFSSPPASTSSAYTATSASVCDTGDTASAAASPPSSDYLPSSPLASQSYSRPCSPFPRVTSASLAASTVSTSAPSSAARSRAYSSASFASISSLIDPAATASTTTTTCATPAAATTAATATFADSTSKRSRYNKQELHAARVQRSASKSVSFGSSPPPGDRRTSIQTRFKRSASSPAEALAAVEPPKDQGLTKMAFAEQQRWITVQQKTFTKWLNTKIEVRNLQVNDLVKDLSDGVVLIHLLECLSNESLGRYASKPKLRVQRFENANLSLDFIKSRGIQMTNIGAEDVVDGNRKIILGLIWTLILRFTINDINEEGMTAKEGLLLWCQRKTACYDEVDVRDFSASWNDGLAFCALLDIHRPDLIDYDSLDKSDHRGNMQLAFDIAHKEIGIPKLLDVEDVCDVAKPDERSLMTYIAYWFHAFSQMEKVENAGRRVEKFVLNMQGAWEMQSAYERRMAALLAALEGQKENWQTSKFEGTYADAKAQAAQFAAYKRGQKREWVAEKSELATLLGNIKTKLGTYRLRPYEPPRHLSLENMEIEWAKLSKAEMKRAQLINETIRDIKNALRKSFADKANDFAMALNAMQLAISGLEGDIEDQLELARQLNLKIPPLDKYLETIQVVDTQCMEANIEENDFTTYTLDELDYELSLVKSSVQKKLAFLDNQMVARNMTNLTPIQLEEFESVFRHFDRTDSNSLTELEFSAALASLGLVFSEDEMHDYFVETSHGRDRVTFEQFIRFMVEVTEDQNSAEQVFQSFREVADGKPYITEMDLRHSLVPDEVIEKLTDIMPSHSGPDMQVDRGMPQYDYISFMDKLMADVDDETYGEDSLLSGEGDTQDDDDSYESSRHSGQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP58</accession>
    <name>A0ABR3YP58_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_005897</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000228">
        <property type="protein sequence ID" value="KAL1889174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="107"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="158"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="570"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="708"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="29"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="57"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="175"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="570"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="823" mass="90023" checksum="37D77694C300A3EF" modified="2025-10-08" version="1">MANCPTSRSDTNGYGAAVQKPPTKRQALASAAPASAPASTTPESATESAPESAPTSIPTLTPTCNSPSGSVAAVGPQAESKAEFHPPSQLQPPTPLAKPVRRRGTVACGRCRRLRSKCVHDHPAPPCQTCKLVGGLVEAQCSFPKRGEKDVDRQFRRRTTAANTVQRTEAKKGTAPAAAPESVVSPSSDTNTEKAVSISTQNDGLYSSAVTPVSYACSPPPRPPAAAALISRFPDPPGPSDARSLLPPIDEVVEGCRIFVTSYFQLGFIPKSIFLERLIRPSENVSTFLLCCILCISARFTPKLVQRYGGARKATDYFVEASRRMVPTEMYLPSLERIQAFFLLAISQWGNGDKDRSSMDMGIAVRMAALLKLHSEESYALPPHAPAERIVQSESARRTFWMIQSQENLHSGYKTPAPFPLEDITTLLPCDEKDFAFGDLPTERAAMAGTPPGLANPSLVYSPRRCLFATLIQVHGLWGKVARRACRTDHSINKAPPWDASSEYARTITELNEWEASLPQDHCFSVWNLRGWKSESLHLAYLAVTMVIRLSHIVSRRIYLEDMLTTLTSSPPDQNLPGSTPSMAPDADEPVPNIPTTSTRETYPDAPGGFWAQMATELFTNVQSLHEQIDAFFSMRTPEEGFPQILVFCVYMCGSLASYLWRSPSLCPELAPRAETMANRALEVLSELHPAWPMSSKWQKGLQQIATPLNGKSPAEGPSQNQTPLPLERRPGGASDCEPNTCKGAGTVFHFPVRHQQQPQFHGPAANPQYQHLTSNPHVQQSYEPHSSHPHIQGMHSFPNELFDAELTAFLQGDFQFESFDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPA3</accession>
    <name>A0ABR3YPA3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_005651</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000205">
        <property type="protein sequence ID" value="KAL1889767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="5">
        <location>
            <begin position="19"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="74"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="75"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1889767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="641" mass="69269" checksum="EE0A0FD618222689" modified="2025-10-08" version="1">MAFVQPESNAAVNDCPGSDPVVTIGYGQYLGFHFPAEVSDCPHGVDVFHGIPFGTDTSGANRFCRARMAAPLAEGEVRDAKERKSTAPETGGGNNDDEGEDCLNLQVYRSATSESHGRSRNECDGGGEDGIKGKTSAQNLPVVVFFHGGSFNFGSSLVRNLRSMAAWSRSPLIVVAANYRLGLLGFLGGAQVSKLAGMAPHEDAPGTLNAGIWDARLALDWVQKYIGAFGGDKTNVSLMGLSAGAHMVGHLLLGYEAGAERPFRRVILESGAPTARCVIDVQHPRLTEQFNAFLDAAGISRECDDPNQPAKLLSAMRALPLSHLCRAAYSVWEHDAPSIFWPFQPVVDSGFTSPLDSTSTSTSTMTPTPTTIKAAPSLLWETSRADRIPLMTGFCTNEGALFVPTGLNTNAEFRAFFARLLPGAMTSADLDELEQLYPSPDILGSPYAPASIDEQLRYGAQWRRLEAAYAHWAYITPVLYSAHMAGSRHKAPARVWEWASESQPYAMSCHGDSELGVTHDMEQLDGLPGLTAVANRMHGLLVDFIVGNGDVVDVGEGGLSDWPLFVSPLGEGREPDRTPGRGKIMVFGKGNDELVYETGGRYGTPWQVRDMTEHEIAACRFWWARRYLSEGMCGIDKVNEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPH1</accession>
    <name>A0ABR3YPH1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_005639</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000203">
        <property type="protein sequence ID" value="KAL1889842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037869">
        <property type="entry name" value="Spp1/CFP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46174">
        <property type="entry name" value="CXXC-TYPE ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46174:SF1">
        <property type="entry name" value="CXXC-TYPE ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="8">
        <location>
            <begin position="168"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="77"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="336"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1889842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="543" mass="58730" checksum="2CAE0DDADB88031B" modified="2025-10-08" version="1">MDLDELPSAGLTDAHYENLELFPEVTRADSIASEVPQFDTELVSSNTTASPAAFSTTASQLGDDLSNIAIDPKPFAANKSHVKKKGTGIRKLPNGTGVTSMATKRPKATSGAKTSTTRRPKAKPSSSTSALDASGANGVSSSSGPGGIANGSSAVRDSPTVGDSDDPGTYCLCHGRDDHRWMICCEKCEDWFHGECINLDTEIGESLIEMFICPRCTDGNTLVTRYKKTCSLDGCRKLARSYAPAAEADDEIKGAAGAVEAEDRYTNSVFCSDEHCYQWWEQMVARLTPASTIPPAVIGKLSREDLLGVIASGLGYVDEATGAYKLAHEPFSAPVSKEESEDMHLSTEERSLLSKSADDRAELASEIELCSKMLQLADQVTERHKAAVASGFITNDICGYDSRLDSVGVQAAFAAFLQTEEGHASCTQGTLQAPKSELAVIAEMEKEDDKERKKATAGMCDKKRCKAHQGWAAMLHKAVKNQIRQLTSQTADLLCEEEVVRAASLERYRRKKVEKNWVETVEAEKRVKQEEADKTIGDAMDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPP0</accession>
    <name>A0ABR3YPP0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translation initiation factor eIF2B subunit delta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eIF2B GDP-GTP exchange factor subunit delta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_005468</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000188">
        <property type="protein sequence ID" value="KAL1890275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="entry name" value="Translation initiation factor eif-2b, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10233">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10233:SF14">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="11"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="74"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1890275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="457" mass="48934" checksum="520ECB1C8D01DB30" modified="2025-10-08" version="1">MTQQPVPSDLAAAASPTNLAAATTSATATPAPEKPATAGTPAAGAAGEKKRTGAQLKAQKKAEKATRRAQTKIAAPPTVATAAGPGASGADTKKQKGKDSGQTTPAASRQAARQAAQAVPAVPDKEAKKPTIPDCFSHLSMAKRIQNTQADKDVHPSVLVLGQKMSSFALSDSIQRLEATLLALRQVIDSYSAPQGTSMSRHLTPHVLNPQIEYLAACRPLCFAMGNAIRRIKVVITKIEIDTPEAEAKQMLFEVIDSMLHERIIIADNVIAHNSANLIKDGDVVMTYASHRLVEISLKLARANGRQFRAVIIDDPFQLDGLTLAKRLKADGIHVTYYSDLSGLRAGLEDATIVMVGAEAMFSNGAMYARSGTADLAIATKTFGTRLYALNQSINFTDRMALDSLTYNEIDPDLNRETGIRLLFDTTRPEYIGSLITDYGETPLSTVATLRRLQEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPX7</accession>
    <name>A0ABR3YPX7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PDZ GRASP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_005441</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000186">
        <property type="protein sequence ID" value="KAL1890365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007583">
        <property type="entry name" value="GRASP55_65"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024958">
        <property type="entry name" value="GRASP_PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12893">
        <property type="entry name" value="GOLGI REASSEMBLY STACKING PROTEIN GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12893:SF0">
        <property type="entry name" value="GRASP65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04495">
        <property type="entry name" value="GRASP55_65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51865">
        <property type="entry name" value="PDZ_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PDZ GRASP-type" evidence="6">
        <location>
            <begin position="117"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="260"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="262"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="301"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="351"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1890365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="366" mass="38775" checksum="90911D597CAFC652" modified="2025-10-08" version="1">MFNALNRFISKLDGESPQQAAARQASLYGFQVLRNTNLELAVEPWFDFIIGINGRPIDNPDPSLFAKEVRNCGGASVMFTLWNAKGERTRDLHIPVSRETPSLGISLQWTPLAVAANVWHVLDVAANSPADLGGLLPYGDYILGSPDGMLYGESGLSELVETHLGMPLRLFVYNNEYNVSRTVTIQPARDWGGEGILGCVLGYGALHRIPAPLSEPATAPGETMFDSNKGNGITASSTADGFIPVSAAVQGTPSASFIPAMTSENNSPLSSGSAPHIILPAQTGPPPMGGAIPARKKKDKSAHSKADFMDDYFKEEEKKSREADGAPSRSATPLPPPPKAGAANLSPPPKASTSQSSSPPKATEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQV4</accession>
    <name>A0ABR3YQV4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">3-oxoacyl-[acyl-carrier-protein] synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CEM1</name>
        <name evidence="11" type="ORF">Cpir12675_005259</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8 9">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000174">
        <property type="protein sequence ID" value="KAL1890701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017568">
        <property type="entry name" value="3-oxoacyl-ACP_synth-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03150">
        <property type="entry name" value="fabF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005589">
        <property type="entry name" value="PRK07314.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712:SF336">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="POLYKETIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000447">
        <property type="entry name" value="KAS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="10">
        <location>
            <begin position="1"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1890701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="422" mass="44085" checksum="B770A3DBD0881B99" modified="2025-10-08" version="1">MRRVVITGLGALCPLGVGVQHVWKRLAQGASGLVSVAQNGPEWKSLTSTVAGVVPLDMWNGGAGFVTSAEKRRLSLFSQYAIAAADMALDDAKWKPEDGTDRAQTGVSIGNGIGGFQEICTQSRSFDGGGQKKVSPLFVPLALHNMAAGHIAMRYSFTGPGDCHSTACTTGADSIGSAARAVAYGDCDVILAGGSESCVNPLAFAGFGRARSLATAFNDDPAHSCRPFDQSRDGFVLAEGASVLVLEELEHARNRGARIYAEIKGYGRSMDAHHMTAPWDDGRGALKAMQRALKDARISADQVDYINAHATGTVVGDKAEAAAIAALLRGCNNKAMVSSTKGATGHLLGAAGALEALFSVLAISENMLPPTLNLHNPDPEIDPSLRFVGPKAVHMDRVDTVISNSFGFGGMNASLVFSRLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRC4</accession>
    <name>A0ABR3YRC4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Exocyst complex component EXO84</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">EXO84_2</name>
        <name evidence="10" type="ORF">Cpir12675_005612</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Secretory vesicle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EXO84 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000201">
        <property type="protein sequence ID" value="KAL1889924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1220">
        <property type="entry name" value="Exo84p, C-terminal helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1210">
        <property type="entry name" value="Exo84p, N-terminal helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033961">
        <property type="entry name" value="Exo84"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032403">
        <property type="entry name" value="Exo84_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042561">
        <property type="entry name" value="Exo84_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042560">
        <property type="entry name" value="Exo84_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21426">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21426:SF12">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16528">
        <property type="entry name" value="Exo84_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25345">
        <property type="entry name" value="PH_EXO84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08700">
        <property type="entry name" value="VPS51_Exo84_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst component Exo84 C-terminal" evidence="9">
        <location>
            <begin position="536"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="88"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="286"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="218"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="127"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1889924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="749" mass="81939" checksum="BB9BA151C385B7A3" modified="2025-10-08" version="1">MSLSLRSSKRKGGRTPISAKLISGPIVQSVPIAANNATILAGSGASLPSNAPRSVPAMSAAPAGSAIGGGGPAAAGPPPAAVGAAIPEARRRVAPPAGDKTSDLVKRRYSTRFNNANVPEWEAGAPPMMPPMPSIPSVPSLPHPSQQQYENRSRSRSQGGDDPSGAGGEVRDPRRPPQSRDGGGRGGGGASGPGPQVDLKALRDPNLSADQYVSSVLAEATDEEIRSFEDSLRKVKSRAAYALQQNVMQNRTQIIKISKETEKLKTEMRTLRNLMAELKVNTTALRTSSSKSQEGFGGDGLASGIGPGSGAGMGMGMSKKDKRSSITDRSALWNSQMQALYKSVEGSQKFFPNSLGRHVLQNGGPWIELDNATYKSRRAMQIFLLNDHLLIASRKKRKNDGPDARGPATKLVADRCWPLLDIEVVDMAGTGDTTVGRSKLADAVMVRGVGQDTFIYRTERPESPDKNLLMLNIRKAVEELRRSLQSEMEANNKAKDTINYFASRDPGLLQNTELLETLSDVKDMLIEVGGKQHNLRWVESQMDELDIDISLQNLEPAVARVEKLRGLARGLKTNVVAQDFITFKVEERCGKLAELILHRLAVTHGLLIKTRENANWLARLGFEDRARETYLATRREMINTRSRLCIFQGDLHMYIWEISFVYFKIIRHTVSCFQACFPPVMMSVCVKWAKEMVEAFNEILARQLSSTQRGGDEWNQCISRAKEHAKFLSEVGLDFQTLVGKNLAGEEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS39</accession>
    <name>A0ABR3YS39_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="8">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GLC7</name>
        <name evidence="10" type="ORF">Cpir12675_005265</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000174">
        <property type="protein sequence ID" value="KAL1890707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07414">
        <property type="entry name" value="MPP_PP1_PPKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050341">
        <property type="entry name" value="PP1_catalytic_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031675">
        <property type="entry name" value="STPPase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668:SF300">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16891">
        <property type="entry name" value="STPPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="9">
        <location>
            <begin position="121"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="322" mass="36842" checksum="274CDBF2CB36B6D7" modified="2025-10-08" version="1">MTDQHDADLDSIIDRLLEVRGCRPGKQVQLLESEIRFLCTKAREIFISQPILLELEAPIKICGDIHGQYYDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIIDEKIFTMHGGLSPDLNSMEQIRRVMRPTDIPDCGLLCDLLWSDPDKDITGWSENDRGVSFTFGPDVVSRFLQKHDMDLICRAHQVVEDGYEFFSKRQLVTLFSAPNYCGEFDNAGAMMSVDESLLCSFQILKPAEKKNKYVRGALGGGSASSTPRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSX9</accession>
    <name>A0ABR3YSX9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bud site selection protein, Revert to axial protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RAX1</name>
        <name evidence="4" type="ORF">Cpir12675_004977</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000155">
        <property type="protein sequence ID" value="KAL1891363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052246">
        <property type="entry name" value="Cell_Polariz_PKAAnc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13155:SF1">
        <property type="entry name" value="A-KINASE ANCHOR PROTEIN 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13155">
        <property type="entry name" value="A-KINASE ANCHOR PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00315">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="251"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="RGS" evidence="3">
        <location>
            <begin position="171"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="362" mass="41395" checksum="4A2124CDF5FECE09" modified="2025-10-08" version="1">MNRNRLPTLFEVLSRRTLPPVDLFSFYIYMRDQQRSVDYLDFWLDVAQHMSLCRHYVRELRRSVLVSTPEVGNASKRSSQVLESIGDLNPDIGSPSMSRTEKERDQDAKMSAFLRGDYDSTPRSEHNIASSSHRIDSPVRFDSPGPSQHSMRSTPRDITDSNSPDHTVLRQDIRASAEKILYTFLMPNAEREIILPGVITHDITVAIQEHGRDDPEVFDVAKDYVFQAMERDAFPGFLRMKALGNLIPPTLVLRLIVGLLAMFAAFWAAFVLIFLDKSRTTRCWLTFPFTVGVYLLASYQYSLDPIMALFGFSEYTPFNFARIREPFVRKMLTRRAITVLGITLLVDASLCVLFILVPGKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU28</accession>
    <name>A0ABR3YU28_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004782</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I NDUFA12 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000144">
        <property type="protein sequence ID" value="KAL1891893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052618">
        <property type="entry name" value="ComplexI_NDUFA12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007763">
        <property type="entry name" value="NDUFA12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32470">
        <property type="entry name" value="ADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32470:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05071">
        <property type="entry name" value="NDUFA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="134"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="167"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="180"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="235" mass="26575" checksum="1015978787F225DA" modified="2025-10-08" version="1">MQIKNPSPLRLAWYRWKAMSLPWRKRRFVGYDFNGNTFWIFRDPGGYVPVDTWRRIVQAPNGSHLSELKVPPVWHQWLRHVRPDPPTIDEQVADISRQQNMALLSQLASTRWAAKPRVADLTDSERRLLEEARKVLGSSQPSHTHSEAQVTPNAMAQPNESRRQAATLPSPTISTSHASPVNPITTTTPMPVPPSELKRVKGTLPAGLADPWANAKNPGENWQPESWVPPTVTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU92</accession>
    <name>A0ABR3YU92_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA damage-responsive protein 48</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005206</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000169">
        <property type="protein sequence ID" value="KAL1890899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40462">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40462:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="123" mass="13016" checksum="483E2672654E191C" modified="2025-10-08" version="1">MDFSKLATQAKNALGGSQENKNTDSQNSNNNNNEDSSTGGFGGLASKLNNAAGGGAKGEKNEDMLDKGIDAIQEHVLGQGQQSSETATEQAKDEAIAGFIRKQYKNSTGNDFPIKDKERSYGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUN1</accession>
    <name>A0ABR3YUN1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004725</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000140">
        <property type="protein sequence ID" value="KAL1892036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05288">
        <property type="entry name" value="PGDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041694">
        <property type="entry name" value="ADH_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045010">
        <property type="entry name" value="MDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205:SF42">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE, ZINC-CONTAINING (AFU_ORTHOLOGUE AFUA_7G04530)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205">
        <property type="entry name" value="PROSTAGLANDIN REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16884">
        <property type="entry name" value="ADH_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="2">
        <location>
            <begin position="21"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="349" mass="37644" checksum="4118B2E0266F8C3A" modified="2025-10-08" version="1">MSNLSIVLSERPVDDIIPGKTFVQKITPIPTADQLQDKQILVETLYVSLDPAMRGWLNDSRSYLPPVKIGEAMRASSIVRVLASKSSQAVIGDIVTTMFAGWTQYAILKEGRFDPASSLPKTSCATDLISGVGMTGLTAYFGMTKIGEPKAGDLVVVSGAAGATGSVAGQIAKLNGARVVGIAGSDDKARYLTERLGFDVGLNYKAADFKQKFSAATKDLIDVYFDNVGGEILNMALRKAKPFARFVMCGAISQYNLAEKDKRGPTNLDRVITMRIKMQGFIVTDFAKEYSVAKQELANWLETGKIKRQEHIITGGLAKAEQGLVDLFKGVNTGKLLVEVKPVTPKANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV54</accession>
    <name>A0ABR3YV54_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AP-1-like transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">YAP3</name>
        <name evidence="5" type="ORF">Cpir12675_004626</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000135">
        <property type="protein sequence ID" value="KAL1892270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.100">
        <property type="entry name" value="YAP1 redox domain. Chain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF8">
        <property type="entry name" value="AP-1-LIKE TRANSCRIPTION FACTOR YAP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="4">
        <location>
            <begin position="173"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="105"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1892270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="360" mass="38875" checksum="7CE76B8683077D75" modified="2025-10-08" version="1">MDFPPGSGQPFFGACTQPSYAPFMNMNGLPPQNDINTTNTNSNGASSCANVEAGSGDFCAADTSPPPPIFDGFAPADQFSSDHSNDHINSFAFDAAAAAQFITSPHTSSFAPPTPPILSHAEQTPPRHAPSQPLSAGPMSAGQMHMQNFKFDPSRDDVAGRRGGSNSEDEELTPAQSRRKAQNRAAQRAFRERKERHVKELEEKLATLEASSQQTSSENEQLRRRIEKMSTENQILRATGAAAAAASSSGTAQTPQPTTGPMAYNPDAFYDDMLANHSNKARSHRVVVSETGERLLAIGATWDLIVSHELFQLGRVNLVDISEKLKMQVRCDGQGPVFCEGDIRRAIEETATNNLDDDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV73</accession>
    <name>A0ABR3YV73_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ATP-binding cassette transporter abc4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_005046</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000159">
        <property type="protein sequence ID" value="KAL1891229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18596">
        <property type="entry name" value="ABC_6TM_VMR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18604">
        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF356">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER ABC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="24"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="313"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="349"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="435"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="462"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="546"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="572"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="914"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="951"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1050"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="311"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="627"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="917"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1246"/>
            <end position="1510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="842"/>
            <end position="892"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1891229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1522" mass="168553" checksum="68885D20F4AC327D" modified="2025-10-08" version="1">MPRNHSTLITSLSTRMQALIKSRALSISTVPSYTTHLITWLILTLFSIRWLDSAHNLGSSGILQYGLVAVSLIAISATRLHRLLYSGSSDTQDLAKYRKTSIVYEISAQAARAAAATFFIISAYDNKDEISTAIAATYAFGVSITRLIPNVRWQQTALHHANFVTSLLTMIVLIATWLPCIQTRISCRLNSPSSHGLICLAAAACVSFITPRTWVPPPELIESPAYTQELADNLRPSPEETCSWFSYYCSYDFVTPLIIKGWHGSLKKDHIPQVPWYDDPDVLLPKVKASRAWGKGTTWTVIHYMKTELSLMVLWTMIYNLAELVAPFGLYHLLAYIDDPSKAIIRPWTWILIMSAGPLLRSFAFQQYVFTSTRLVVRIKSGLTQELYHLALNSMEIEVEDTALDGTKKIINATGRLATLIASDIEALYRCRDTIMVLVSLPTGSLGAMIGLYLIVGWPAVVGIGVLIASPPIMVVLVHRMLKYQMVVRKAQDSRMSLVSEYLTLIKAIKFFAWEDHALEKIQAARQPEQNALWTISIIDAIMRQVSSLSGFFSLFSMFCLLTVVVGKPLTASIAFTTITLTFSLKHNLNRIGYISKNITSAMIAVRRLDSHFEKSRPLEKYPEGPTRLVNATFRRTPTATFNLKDISVDFVENGLNVVIGHSGSGKSTLLLGILGETVKESGNVTRPRNAGYASQSSWLQNATIKENILFASPMEQVRYDRVVAACCLEEDLAELPDGDSTVIGENGTSLSGGQRARVALARALYSKTSLLLLDDIFSALDARTAASLWERCFCSDMLISRTVILVTQIPWLAEQADLVVSLESGNIKSIEPHIGVTRRPISSLKDLGGSSSGTPSETERTIDEEGAPNTVGKKFTPADDNKNEDEVDSELNASKSSGRNLTYRYVRYYRHGVLFLFCLFFTVLALGLSTATNLWLVFWTRENEDSMSRLPYYIGIFALLSIMDSVFNMVSAISYKFSFWFTARQIHQELTQALLGVSMDWYSNVPIGRVINRFSRDISSMDSTLPGQLEVVIYLAVEMLYQLASISSIMPIFIVPAAITCCAGMVVGEMYTRTAVTARRIESSSQSPVFSQFSDTLAGLPIVRAQAGMVTEFCRTLAQRLRLWTSSAEVTLNCNRWVGVRVDLATSLVSLGAGVIALWKTGTVSASLVGFSLTSASTLSGSILYLVRYTNDLEVELQSFDRLLEYTSLPLETKDDKPYPEEGEYTDDPAHVIPRNWPRAGDIEFRNATIRYTKDSQDVLTDISLKFKAGERVAIVGRTGSGKSTIVASLLRFTEIVSGQILYDGVDITKVPRKKLREALTIIPQEAVLFTGTIKSNLDPTNTIPEANLQKAVDACKTLASFQSGSQDMIDSSLDDETTETETDVRVLAEGDAEKRLSLDTQVVAKGENFSHGQRQVISLIRAFVRDSQLMLLDEATASMDYETDKGIQEVLRAELCGSNRTMVTIAHRLRTIIDYDTIVVMGAGRVLESGSPKELYQAEGQFYDMVQHSGEKEDLEAILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX65</accession>
    <name>A0ABR3YX65_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GPI-anchored cupredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000142">
        <property type="protein sequence ID" value="KAL1891919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052953">
        <property type="entry name" value="Ser-rich/MCO-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883:SF15">
        <property type="entry name" value="EXTRACELLULAR SERINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883">
        <property type="entry name" value="SERINE-RICH PROTEIN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045674908" description="GPI-anchored cupredoxin" evidence="1">
        <location>
            <begin position="17"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="176" mass="19607" checksum="E5A4E478B1FF8CD0" modified="2025-10-08" version="1">MRLALLTLISAAAVLAAPRQSPPQDNSIEARNGVTRIVKVFPQNIAPVELYLNVGDNVMFKFGDGFNSVVQGEYDTPCYSTGSGFASGSFYNNDKGQYHANAFVIPIRDTMPIWYYNGEFDKCQKFNNVAVINPPRDRSMTIDDYMERASQADDSENFEMKGGLLVQLSSEDRKIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXD0</accession>
    <name>A0ABR3YXD0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Bromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004429</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000125">
        <property type="protein sequence ID" value="KAL1892697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15398">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15398:SF4">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN 8 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="177"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="278"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="520"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="628"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="921"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="993"/>
            <end position="1207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1380"/>
            <end position="1440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="201"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="221"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="302"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="336"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="388"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="406"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="454"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="470"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="520"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="557"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="628"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="653"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="690"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="720"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="777"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="817"/>
            <end position="858"/>
        </location>
    </feature>
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        <location>
            <begin position="938"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1017"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1043"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1059"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1141"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1163"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1393"/>
            <end position="1411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1416"/>
            <end position="1426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1440" mass="152888" checksum="F470CE846DC66E12" modified="2025-10-08" version="1">MDPPELPPEAFTARESYFLFRAIHVFQTLDFTLLSKKLIANEFINGADEFDEARLTPRRLWGLFRHHFLAELPNPPTQLTPDLIVDKYKNITAIDRKLGEIYYTRLKKEVLSDAQREQEAAKRQADLEVEQKRIRESLLKNTNSAVMPTQLAAAASGVGISNAVPIAPASFSTRPVSHLHNLGSHGQTQIQPHRAKSPHTLSSASLAVSPLAAPGPEMATKKSSVTSRPPQPLNSNQTQPVIAIAAHQPTHTPRAILPATTQPASQHPAIQPDIQPTIVRPIAGPSPQQVLQAPGPPPLKAVSTSTNIEAQQTQFHQLPPKPPQPQATPEATAPQISQNVKSQQPQATVKEAGQKPAQVAPSKQPLEPQNSSSPNQTAPVSAITINHSPTPSADTSPSPQPRAQVPAALPSKSQSPQPSSSQAASTPGQVQTLKWERPYTPQHNTPIAQRPVPLNTTAGHHNGASISKNSSQSRSLSPVVSNTSQWTPNRFQVAHAPGHMPEQAQAQALAQAKAQGQVQIQAQTQAQAPAPPKSQAKNLQQPQSQQQQPKPQQSRPQHPPLAAKPPAPNSSATPQTQAVIVQKPQLGQAQQLSQQIQQPLPPLAVNPAVAPAIPSDSVSATLHSVPISIPSQSSSQPSQVQQKSQSPTKPIVQLSQHTRTTQSQNQTKGSSPQSELTSQKTPQTRKKSAPQATVQAVSGVSLSPQQKSAQPVAPKTSFSQTQAVPQPQQQRQPMPSHPTTSLARPADQPLLIHTQPQPQPIPISQAVKKPLVPISAQPFSRASSHSPKQTLAGIPEAVPQGSMKGSAEATASPMKPQPQGESPAQPQAQSQAKPQEKPQTQPQAQPQSSPKRQSQPVPVASTPKQVAKQPVQPEQATPKASPPLITQSQAPSIIATPIHPTVSATTSQALAIAPSASLPQLPVPQLQHNQNPPPMATTPVQSTKPVTSTPQPKTPFAKTSLAIPDHLVPSKIAPISTTTAPASTDALVSLVKPHAAADPQTPAPQKQALFYKRGHGTNWTLDSTPSTPGPANTTVDSPAWEPLSPPPPQPPPTPTLQSGNPITSTGLNPVTPGIIPSIKATPRRTNRPETPMSRGSVLSKRPTRTGRAGPPRTRRSQSIVSQPDELSMDPSDFQGPGSSRIKNEDLSKMEEAGDTTADEGITSRRRGPSSVRAGKRKRQDSMDSGFHRPRPSISTPTPAVQVGPPTHVRWTRGFPRVSASVLDQIGSHRDANMFANPIREKDAPNYSTIVLQAVDIASIKKAISHGNKIAIQAAAALPDGDPGTALVDLPISEDLVPPRGIINSEQLERSLVHMFCNAVMYNPDPDRGPGPAFLAGANHGGNGSENIGYQVDEFGVVNDTRNMFLEVDKLMAELRGAEMQRNGGSLQPPPVPTASSVSSGAATARAMSLATAGGGDDTDELDELAADEVASTSTRRSRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXH4</accession>
    <name>A0ABR3YXH4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_004321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000119">
        <property type="protein sequence ID" value="KAL1892953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1892953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="171" mass="18612" checksum="48B05243D8B1D936" modified="2025-10-08" version="1">MLSFYHAVNAAAFVKLSALFVKMSQDASIGLSPDSVYTFLRTFTLTDQTSVEANIESAINLAYEISKEGLDITSKSTIDKAYHMSGIDRENQPVCEKAPAFIEASGGCSSKDNQIFNGNLQQDALLNYNISSIATAKTEHDMAISYNNSLQDGFNPPELAPDYVLMAGQHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXW4</accession>
    <name>A0ABR3YXW4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004642</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000136">
        <property type="protein sequence ID" value="KAL1892174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF76">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="29"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="495"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="517" mass="58147" checksum="9D2268DF73BE9535" modified="2025-10-08" version="1">MPILLPDPAPKLNPEVLPTWSRLNNLNLNNVNVTKVSPEIGYGILAAQDIVGPQHEVTGSFNDLPVLRVPEDVVLSQLAIEEYSKVEPKFWQLLEAYGQASQREKFVLYLMFHRINSRHDISILPSPWTEYVKFLPEDIPTPTLWPASHIPLLHGTELAGPVQAKLNVLEHEYDRLVQISQDLLFLQDISFSPAGIALRDWQLADAWFRSRALEIPGLGTCMVPVLDMANHNATNHNAYWDRESATGDVVLMLRPGATVAKGEEICINYGADRSAAEYLFAYGMFDMDSAVRPITLPFQFSTTDPLAGAKHAVFKTRTPQLRITLPDDLAEYERGQRYWECPYAYLSALNAEDGLTFQVAQDLEGRQELHMFLDDEDITDKAMDIESLLKDLAIWPVINFRAIQMMKAELSVDDILRNFDITKHEELWDDKPYTYALAAQFAYTEAQLIQTATQYFESAAAAQFEDAFLQAYLQAINNGAGISPRQLEVLIGEKGGKRHEARPQEGADGDVPSILKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYC9</accession>
    <name>A0ABR3YYC9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">STAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_004177</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000112">
        <property type="protein sequence ID" value="KAL1893394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018045">
        <property type="entry name" value="S04_transporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00815">
        <property type="entry name" value="sulP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01130">
        <property type="entry name" value="SLC26A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="404"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="462"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="485"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="7">
        <location>
            <begin position="570"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="603"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="828" mass="90019" checksum="22CE362C39AE7E60" modified="2025-10-08" version="1">MASKSANAGQILAKVLGIKIDDYSNDSVTRGESVFSITTADTDTFVEEEPTTVEWLREQVPSGRNISAYAISLFPFLDWAPFYNLSWLTGDLVAGAVVVPQGMAYALLANLPPEYGLYSSFMGVALYWIFATSKDITIGPVAVMSTLVGNAIVDIRDNHPDISATDVAGTLAILAGGIICFIGLIRCGWIVDLISLTSLSAFMTGSALSIASGQLSSLMGLTGVDTRDAAYLVFINSLKHLDTAKLDAAIGITALVLLYLIRSSINLAAKRWPQHKRSLFFTNTLRTVFVILLYTLISWLVNHNRRSSPAFKLIGHVPRGFKHAGVPNINSHTCSVVGSYLPATVIVLVVEHIAISKSFGRINDYTINPSQEMVAIGVTNLLGPFLGAYPATGSFSRTAIKSKAGVRTPFASVITAVVVVLAVYALPAVFFYIPKAALSAVIIHAVMDLITPPNTVYQFWRVSPIEVLIFFVGVFVSIFSSIENGIYSTVCISMAVMLFRILKARGDFLGRVRIQSVLNDRVIGEHYTDDVGAYGTFKSSPANAGVRNLFLPINHGDGSNPIVAVESPYPGIFIYRLSEGFNYPNASHTLSYFTRTIFKQTRRTSPQTYANPGDRPWNDPGPKKAKNVACNEDLPADDDDEASKPTLKAIILDFSSVNNVDITSVQQLIDVRNQLDRYAAPEPVDWHIACINNRWTKRALASAGFGYPLEQNLETPGLQSRWKSIFSVAELGGDDSAASVAEKEANNHVTAVRVPDEETISPAKLPEANQTHLRRRRRGVVVHGLNRPLFHIDLTNAVQSAIANVEARTEVYEGVVHPVENGGVAKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYJ0</accession>
    <name>A0ABR3YYJ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004107</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000109">
        <property type="protein sequence ID" value="KAL1893454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF11">
        <property type="entry name" value="AMP-DEPENDENT SYNTHETASE_LIGASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="2">
        <location>
            <begin position="148"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="563" mass="60770" checksum="CE0D6A3A1C9B4972" modified="2025-10-08" version="1">MDEVAKESASFFTRVIAILKFWTQSATDDWSLSSTLLLIVLFTLCFLSTVWTYDSELHPLQLARQSTRSEVRQPGESALYRTAALGFNGLVKGLDIVDEGAPKFSKGRDGDLRDVWQRFAKGTDDGKLSTISTVLGLQKTEVHNIDALSRQISLVASHITRNGGARVAVYLPNSVELLLAVFACSFAPNVTVTLIPYDVPPSELISMLRHAAIDTIVTVPGMLPFETIADSCPTLKHLIWVVDEGTSSIDWKILPESSSSSVKATTWKDIVNATEAPQLSVDTNAVPGDVAFFWSTEEMSSFTQKNVVSAIAAQLASIPSSETLGPKDTFVPADVLTDNFTFIITMTAMFSNANISINSVAGKEANLSIATQCAPATVISVSPEQLLLYHKEGMSSICGIVTKWIHGYRQRKLENFGVFPSTTGFMADMEVSNAPPLGTENTQVRAIYVAEKAGNKPVISSKMLSDLRALTGARVVHALTSAVAAGSIAQSLWYDYRVHEGQTAHFGPPSPSIELILKDKGEHFTKDYKIQGEITIRGANVTGGSANTGAIGKINDDTTLSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ10</accession>
    <name>A0ABR3YZ10_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_004521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000129">
        <property type="protein sequence ID" value="KAL1892549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1892549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="60" mass="6518" checksum="19EB00CE5E403AB5" modified="2025-10-08" version="1" fragment="single">MPNSIVDEDYRTVSDALMNATSGNIQCMINAGDVCRQKRGKLAVIQENSMAKDTEDPTNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZN2</accession>
    <name>A0ABR3YZN2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ADF-H domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003947</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000102">
        <property type="protein sequence ID" value="KAL1893828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11282">
        <property type="entry name" value="ADF_coactosin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829:SF56">
        <property type="entry name" value="ADF-H DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829">
        <property type="entry name" value="CORTACTIN AND DREBRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADF-H" evidence="1">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="142" mass="15608" checksum="26EBEDBD7A494A02" modified="2025-10-08" version="1">MNSPEISAAYDAVRSDKDSINWLLVGDLPDTKKLGLIKTGSGGLAELVGELQDDQVKYAYVRQEYANDSESTRVKFALIIWIGQNTKIMRKARVSIESGEVKKVLSHHSIQVDADTRSDLNEKDIVARLRKAGGADYNGGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZS7</accession>
    <name>A0ABR3YZS7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SKN7</name>
        <name evidence="10" type="ORF">Cpir12675_004387</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000122">
        <property type="protein sequence ID" value="KAL1892804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014402">
        <property type="entry name" value="Sig_transdc_resp-reg_Skn7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002595">
        <property type="entry name" value="RR_SKN7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00434">
        <property type="entry name" value="HSF_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Response regulatory" evidence="9">
        <location>
            <begin position="336"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="547"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="586"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="547"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="586"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="602"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="7">
        <location>
            <position position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1892804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="627" mass="69164" checksum="9DC49E2E0242D9CF" modified="2025-10-08" version="1">MPEESGSGGGGGNSNSSDFVRKLYNMLKDPENHTIVRWGSEGDTFVVLESDIFTKSVLPKHFKHSNFSSFVRQLNKYDFHKVRRGEESGQSAYGPNTWEFKHPGFKADGKENLDNIRRKAPAPRKTQPAEETMVAAQNQLSMVTDAVTATQQQIHAMQAHINALMESNKNMNIEFGNMHKLLALQRTVNMELVGFLENRCKSAPSINGTQEEAELQRIRDFLGMNVIDEAKRSIFSPGTSEQLASMYTGQNVTPMIQDSMELSRYGVYPVGETTGIDPFSAEHMKNIPYQFHPEPNIMVPPTAHIITPTVVTAPESDVASPPASDEVPDWGKRPPLVYLIEDDKICSRIGYKFLRTLGCNVETAEDGLQAVSTINTRNLKFDLIFMDIIMPRMDGVSATACIREHMPNVPIIAMTANIRAEDIQYYYSHGMSDVLAKPFTKNGMLSTLRKHLPDFRSKSSPEGVISHSNGVVAGSPSNGLPPPSNGIGTPGAMIQQAQAQTQAQVQAQVQAQVQAQAHAVQMHQAQVQAQVQAQAQAQAQMNAANGTNWQSPRQISHQSPGQSGPMDGSYINNVSSQVMVPSQRMQYSTNGSMPSSHQATPRLHDMGALDDRPEKRQRIFDPESTFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZT4</accession>
    <name>A0ABR3YZT4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1996 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_004095</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000109">
        <property type="protein sequence ID" value="KAL1893442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018535">
        <property type="entry name" value="DUF1996"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662:SF7">
        <property type="entry name" value="DUF1996 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09362">
        <property type="entry name" value="DUF1996"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045949438" description="DUF1996 domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1996" evidence="3">
        <location>
            <begin position="33"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="359"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="390"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="424"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="493" mass="52193" checksum="EA5DBEE2A48A6226" modified="2025-10-08" version="1">MKPSLIVLSSSLGLASAFWRMECPSRVGNARLDPIINPGGISAHMHSIYGSSGFSKTSGFGELHGAECTSCRVTQDKSAYWTPSLYFQDTATGEFTEVDEQGGLLAYYFLNHDKMTAFPEGFRMLAGTNSRRSFTTGNPMEGDPPKSSWAAEGITSQKALAERAIGFNCLNYAKQGEATLSRHYLPEKSWLDANCPDGIRIELMFPSCWNGKDLDSADHQAHVAYPNLVMTGECPDTHPVGLAGIMFETFFRTQEFAGKAGRFVVANGDPTGLGFHGDFITGWTPSVLQQAIDTCTSGSGLIDDCPVFNVVSKSESSDCKLDRIETAAVSSPGPLKALPGNVAVVDANGSPGGSGAGSGMQTSSSLPLAAPPPAAHPPPSSSSSPPPPATAISTPKSTPRLGPSRPSSRYGSGGISIAAVPNHTTPAPTTTSTTSSVDPDAGKFYSTQWSTDSHGMVYKILWLVVYVTEIKWVDAMPTTTFKSVMTSKPAQYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0I6</accession>
    <name>A0ABR3Z0I6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_003787</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000095">
        <property type="protein sequence ID" value="KAL1894145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06926">
        <property type="entry name" value="RNAP_II_RPB11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00261">
        <property type="entry name" value="RNApol_arch_Rpo11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037685">
        <property type="entry name" value="RBP11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009025">
        <property type="entry name" value="RBP11-like_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008193">
        <property type="entry name" value="RNA_pol_Rpb11_13-16kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022905">
        <property type="entry name" value="Rpo11-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13946">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I,II,III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13946:SF16">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13656">
        <property type="entry name" value="RNA_pol_L_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01154">
        <property type="entry name" value="RNA_POL_L_13KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RBP11-like dimerisation" evidence="6">
        <location>
            <begin position="31"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1894145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="122" mass="14109" checksum="A52AB7D465007CBD" modified="2025-10-08" version="1">MNAPDRTELFLLGEGEKKVEEKPFAGLPHCSDFVLYKEDHTLGNLISEHLKKHKNVMMAGYKISHPNVPELFIRIQTDGSISPREVLMEIIKNLMRDLSTFSNEFTREWELRRMVSAGDNLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0K0</accession>
    <name>A0ABR3Z0K0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_003794</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000096">
        <property type="protein sequence ID" value="KAL1894106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1894106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="152" mass="17749" checksum="3FF638CCD0E31F9B" modified="2025-10-08" version="1">MYRRLLTPGHGMGSCRNPHVSWNIPHDPAWYATKRVAPRSHSRKMRKHPYAGARILVYRWALDEMLRKAPKTLEFSERELAYMQLGLHRKKAADSIKEIEQAKEDLKPRVPVVHISHRLEMDELQLASIDMVPADELSWGFVVPSRKRYPTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0R5</accession>
    <name>A0ABR3Z0R5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycosyl hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000116">
        <property type="protein sequence ID" value="KAL1893119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053169">
        <property type="entry name" value="MUG_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47791:SF2">
        <property type="entry name" value="ENDO MANNANASE, GH76 FAMILY (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47791">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 191 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046779166" description="Glycosyl hydrolase" evidence="2">
        <location>
            <begin position="16"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="611"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="643" mass="72075" checksum="270A528C6F5F2A6E" modified="2025-10-08" version="1">MRSLLIYLFLISVVAVNLNTDRRNWLRTVRRKYVCSIFSSPNLPEDDCWPSSPTSFLEDEPIEPVSSSHRAPPEILDDAFDALSTMQQNFFHSELGTWPSSIDWTAAVLQTHLSGMTASLSQVFSTLDLAENSTKANMLDLYFSQTVASYFGQDHLAIRGQAYDDMLWVVLGWLEGLQLIKTQNASFYNHPSVGSSGTPQLSNALESQIWHGNYWTKPFAHRARVFWELASTSWDAKLCGGGMNWNPHELVYKNAVTNELWISASIQMYLYFPGDDITTPWQTTATSGLYPSKDPRYLQAAVEGYKWLMSSNMTNSYGLFVDGFHISGRNGSLKCDQRNEMVFTYNQGVILTGQRGLWEATGSPSYLHEGHALIQNVILASGWNFKTGAPRDQVKNLPPGLLPPWRGLGRGGILEEMCDSSATCSQNGHTFKGIFFHHMSHFCKPLDTRDLSVRSTERSLGYDESRFNTISDTHAHACRSYIPWLKHNAQAALQTRDKSGIFGTWWSAGLLNLTNNVPNHGGVLMTASMVDYRNHPVERVNEWGNGNMPRMAIPGVSEDHKYYAVISPQDNKEDEDHVLDTPPSQQVIGSYGDQDSKKNDTPLKAGGGHFTRGDPNDRGRGRTVETHNGGMAVLRAWWDISRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0Y6</accession>
    <name>A0ABR3Z0Y6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003898</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000100">
        <property type="protein sequence ID" value="KAL1893879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="143"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="293" mass="32554" checksum="C3AE915266E91188" modified="2025-10-08" version="1">MTASHQPEGPWALRYNRHTFGHNNKSFQPPYCRNQPFDAQELSRRLLAVQVQQQKQEQQELQKQQKQHHKLQKLQTASLRKRQSMPLPRRLFSTKDNTTPKPDASNPESHTSHHTTGPAPKSASSTSSSSSSSSSKVDDSRRSSTSGGASATSISTSISLSSESQQQSSKPERSGHHHTSDQQRQHSVSSACKSRIATEGDEFSPSPAYTYRRKTYSRGSHPERADWIEGDEAKTRKKIWSRPSIMGLKHRLGGNGGNSSSHGGKQEVESLAGEAPHQQRAGLLRRFRKTPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z131</accession>
    <name>A0ABR3Z131_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Arrestin C-terminal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003729</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000093">
        <property type="protein sequence ID" value="KAL1894301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053060">
        <property type="entry name" value="Cytokinesis_Signaling_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36419">
        <property type="entry name" value="ARRESTIN FAMILY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36419:SF1">
        <property type="entry name" value="RHO1 GEF LOCALIZING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="1">
        <location>
            <begin position="185"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="401" mass="44868" checksum="E103B599B5A2804D" modified="2025-10-08" version="1">MAAFVRVSGLPNRNFLVGYTGISATVPRIQGTVEVRPSVGYSAPVSVSLVRICLQRRESIHPAAENMARRHLSAPRRENVDVIGKEYVLYTCTAGRESDSVVVMDLPFMIFIPYGRGGNEVSRLIPPATLQLPSRTAETFYELVVTVQQGPSVQHKYSFPIPLLRYDTLSTFGMYNTPKPNRANTDSLAYLEISLPKRSYGPLDPINVYIRITPNPDFMKKARKVTIEKITLQVEEEITYNPEGDESTKKVNKLAKKTESIRERLPEAGYMTSLGLIFPARELRDSEGVIKPPKPGFPQYEVTSFTTSSYLYRIEFFLTIKATLSSARDIIIREPIIVCPFDSESCKQEMEAIEQAARDASHIDKHSPRLPSPHVVYANQPNSLSALGLCLVGDQKKPLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1A9</accession>
    <name>A0ABR3Z1A9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pre-60S ribosomal particles component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RRP15</name>
        <name evidence="3" type="ORF">Cpir12675_003861</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRP15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000098">
        <property type="protein sequence ID" value="KAL1894077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012459">
        <property type="entry name" value="Rrp15"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13245">
        <property type="entry name" value="RRP15-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13245:SF14">
        <property type="entry name" value="RRP15-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07890">
        <property type="entry name" value="Rrp15p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="173"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="331" mass="35797" checksum="E3AF17C1E7BE4707" modified="2025-10-08" version="1">MAGPGAARKRARGNDSARPHKKSKVHRQQAYHSSSEESEAEDFAAVNLEDSDNENILDAPADMGASDGEETIAISSTKEKKGTKFNTKSAKTVPSSSTSDIATTNASGGDDDDESMLGNDEFDEDMLAAEDSQEDDDEDDEDDDEDDDITGLQGPAVRQNSKSKRNDPTAFATSLSKILSTKLSTSKRADPMLSRSIDAQKASQAIVDSALESKVKRQLKEERRVALEKGRVKDVLEPKVQGQPKVQLSASKCMEEERKLRKVAQRGVIKLFNAVRAAQVRAVEAQRDTRKGGMLGLAKREAKVQEMTKKGFLDLIASGGGGLKKGPIEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1X4</accession>
    <name>A0ABR3Z1X4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003597</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000088">
        <property type="protein sequence ID" value="KAL1894608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045796496" description="SH3 domain-containing protein" evidence="3">
        <location>
            <begin position="25"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="273"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="246"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="405"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="588"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="605" mass="63371" checksum="C4350F1B2D28CB2C" modified="2025-10-08" version="1">MTYPSFLAVAMALAAASSPALVSAATSDCFALSGSTACPAWSAASISLGDSLAETYSFMSYVTDLTSFDREIGNYVNTSWIKEKYQNQFGCNAVNYRNATEYYARWTKSTICSALVQMSASECGVTTSNSMPLCATSCAQFASSEAYVTEDNSLCGNSSSNAMSLIKADFNLCASSDETLSSTCISGSSNEPTNCGFGDSTIGLCSYCATGGTNSTDTCCYSANAGDICANVTLPSITSTMTFSLPTATSTSGSSPSAEASNNKSDDGLSGGAIAGIVIGSIAGALLLLGLVWLVRAFLRRRHRGSSNGSVFNQPSPARKGTSSIPPMSQHGAKSSLSAPPTAVTPPPQGYEVLPGGRIARMSALEGHANVPSTTSGNAGITPTSRRHHINDRSSSDGFGESPEPRAAILRPPPAAVRRNASLSSSSLLNTDEPLSPTSAGDMSSAPGVNSQQSEQLPFFKDYYSHEDIHPGDRVAVLWAYQPRAPDEFTLERGDMVKVVGIWDDGWATGIMMDERAEEWEARRQAQRDSGVSSASATVGRDVTPPVSGEIKAFPLVCVCMPDHWRKTVEGDISTEGGASSGSGLCAGGMFQTQQPLQQQQEPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z250</accession>
    <name>A0ABR3Z250_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosome assembly</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RSA4</name>
        <name evidence="6" type="ORF">Cpir12675_003765</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000094">
        <property type="protein sequence ID" value="KAL1894284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF0">
        <property type="entry name" value="NOTCHLESS PROTEIN HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="142"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="185"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="229"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="278"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="400"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="442"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="484"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1894284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="517" mass="57101" checksum="321A14EEB500B400" modified="2025-10-08" version="1">MSTILPPPSKRQRREHLERTGIQQDVTASTGKDIGSFKARFVDSEGHQLAEVIEVPLADASEKNISLLLNTLLGRDREEFLPYKFRVHIPDSDVIVDTYPEDLLVLLQSHGIANPFETTITLGAEPQAVFKVQAVTRMSQRIPGHGEAILCAQFSPATSGRMATGSGDKTARIWDTETGTPKWTLAGHDGWVLCVAWSADGEQLATGSMDKSVRVWDPKTGKAKTTKPLTGHGKWVTSIAWQPYHLWNDDEGPRLASASKDATIRVWVVNSGRTEHVLSGHKGSVSCVRWGGTNLIYSASHDKSIKVWDATKGTLVHTLNSHAHWVNHLALSTEFVLRTAFYDHTPTPVSTAERKEKAKERFERAARFKGKITERLVSASDDFTMYLWDPAQGTKPVARMLGHQKQVNHVTFSPDGNTIASAGWDNHTKLWSARDGKFINTLRGHVAPVFQCSFSADSRLLVTASRDCTLKVWSMASHKMAADLPGHQDEVYAVDWSPDGKKVGSGGKDKAVRVWCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2C5</accession>
    <name>A0ABR3Z2C5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Maturation and nuclear export of 40S ribosomal subunits interacting protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">NOC4</name>
        <name evidence="4" type="ORF">Cpir12675_003669</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CBF/MAK21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000091">
        <property type="protein sequence ID" value="KAL1894440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005612">
        <property type="entry name" value="CCAAT-binding_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027193">
        <property type="entry name" value="Noc4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12455">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12455:SF0">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03914">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCAAT-binding factor" evidence="3">
        <location>
            <begin position="314"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="540" mass="61890" checksum="90753E33A17F7C3C" modified="2025-10-08" version="1">MSSSATKDALKRKRKLAGSEAPKKRRRSVGSDDGIDVGTQILELEAQILESKKHYNNLTKLFDYIEDYMVNSELSVLAAVACCRVFIKLLAAGRLLPKTGLSEKDLVVVQWLRERYVAYRALLLTLMGVDELSLTILTLVMKLLKVEAQYLNDKQDYQFPPFFATNLIKTLLEDCGSEVRKEFISEFVDEFDDIRYFTLRAVKTLVGTWSEDRQFFDTTFEFLSAIDGVPDSNDELQDFYIEKPKVKSHPLFSVVQHKRQAQDAWLALMAHGSTKDRRKKILNDLVQTITPWFLKPELLADFLTDCYNMGGATSLLALSGVFYLIENRNLDYPSFYTKLYSLLDRDILHSKHRSKFFRLVDTFLSSSHLPAALVASFIKRLAQLALSAPPSAVVFVVPWVYNMFRAHPLCTFLLHREIRDSELKKLVENEGFEDPFNPDETDPMETGAADSCLWELVQLQNHYHPNVATIANIISVQFTKQSYNLEDFLDHSYNSLLEAEMSKDVRKAPVVEFQIPKRIFLPQDIDSGVADNLVVKLWEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2N0</accession>
    <name>A0ABR3Z2N0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Inner nuclear membrane protein enriched at telomere/subtelomere region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SRC1</name>
        <name evidence="11" type="ORF">Cpir12675_003671</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000091">
        <property type="protein sequence ID" value="KAL1894442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12935">
        <property type="entry name" value="LEM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1180">
        <property type="entry name" value="MAN1, winged-helix domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025856">
        <property type="entry name" value="HeH/LEM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044780">
        <property type="entry name" value="Heh2/Src1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018996">
        <property type="entry name" value="Man1/Src1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041885">
        <property type="entry name" value="MAN1_winged_helix_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47808">
        <property type="entry name" value="INNER NUCLEAR MEMBRANE PROTEIN HEH2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47808:SF2">
        <property type="entry name" value="LEM DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12949">
        <property type="entry name" value="HeH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09402">
        <property type="entry name" value="MSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="346"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="568"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="domain" description="HeH/LEM" evidence="10">
        <location>
            <begin position="15"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="Man1/Src1-like C-terminal" evidence="9">
        <location>
            <begin position="353"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="75"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="688"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="165"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="217"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="287"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1894442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="729" mass="81167" checksum="B90F06F5A7812CD5" modified="2025-10-08" version="1">MADTDVDYLQPGFDPRSVTMPRLRSIMVTHNIQYPSTAKKQDLVNLFNQEVAPMARKLLKQRARVKRMSSGIVNAGDILDPEDDEDNIVPRPPSRSRSRRSASPIKPVSPRKSSSRLHTESVEPEYVAEPASTRTVRTTRRSASRGLSIDPEPIHATPSARRSRASMTPQVIVQEPTQPDDDDIPDMLSEAEHEESVFTDDNPFQRSPPRAKTPGSTRRKSAGPGTAKRKSAGASSERGSPMGVTLSSIMAQQQQQQSLLPKARSPSAELGRIPSPAPSTQRNLSPSPVPRRSPSPGPFPEYQHDIDAGEEFTPEALQQLEADIAASGQSATASYKATDPSRKFDFATPLWVLLFTIFAAYGVWYRQEKIAVGYCGLGREPTQIIPVDVPVPDWIVPFIEPQCEPCPSHAYCYEDFVVRCEADFIMKPHPLSLGGLIPIPPTCQPDGEKAVRVKAVADKVIEELRTRRAEHECGGILDENGEKQGSLEIKEQALKEIISRQRRKKLAQQEFDDLWDAAIGEVKTRDEVEIIETDSGDLSDTYLSSTSLARLPITCAIKRTFVKGLERHRFGIGAVVAVLVIGLYIRGRYRNYVATSAKIPALVDHVLDRLSKQKETADEEYDDPWLFLPNLRDDVLRSVHSLSERERIWVRVIRVVEQNANVRTAQRESRSGEVGRAWEWIGPVSSDMSGNRRKSVRTSYGVDTATSSSSVKLETPERAQWGEGKRPIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3H2</accession>
    <name>A0ABR3Z3H2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000084">
        <property type="protein sequence ID" value="KAL1894797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046854075" evidence="1">
        <location>
            <begin position="18"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="117" mass="11435" checksum="EF9FB03638CB2FBE" modified="2025-10-08" version="1">MKFLSALTLVLAPLAMAQEPSAAATSTPAPTTTCISTMTLTKTLTLVRTSHTASVYANGTYAASSTGFVSYTSATLSASNTGGTTGSTSVPETGAAGMLSPQGLLAGAAGLLAVALM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3Q4</accession>
    <name>A0ABR3Z3Q4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Plasma membrane ATPase</fullName>
            <ecNumber evidence="10">7.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PMA1</name>
        <name evidence="13" type="ORF">Cpir12675_003482</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O + H(+)(in) = ADP + phosphate + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:20852"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.1" evidence="10"/>
    <dbReference type="EMBL" id="JAWDJO010000083">
        <property type="protein sequence ID" value="KAL1894837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02076">
        <property type="entry name" value="P-type_ATPase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006534">
        <property type="entry name" value="P-type_ATPase_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01647">
        <property type="entry name" value="ATPase-IIIA_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="312"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="678"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="708"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="749"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="815"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="849"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="12">
        <location>
            <begin position="60"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="28"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1894837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="911" mass="98846" checksum="C604FC287BFF7D7C" modified="2025-10-08" version="1">MADTTSAVQPQYEEKPPAIVPAAKGGDDEGEDEDIDALIEELESQDGHQDEEEEEDESGLGGRVVPEDQLQTSTLTGLTSEEVLARRKKWGPNQMKEEKENLILKFFGFFVGPIQFVMEAAAILAAGLQDWVDFGVICALLLLNALVGFIQEYQAGSIVEELKKTLALKAVVLRDGALKEVEAADVVPGDILEIEEGTIIPADGRVVTEDAFLQIDQSAITGESLAVDKRHNDATFASSSVKRGKAFMVVTATGDNTYVGRAAALVNRASGGSGHFTEVLNGIGTVLLVLVIMTLLVAWVSSFYRSNPIVDILRFTLAITIIGVPVGLPAVVTTTMAVGAAYLAKKKAIVQKLSAIESLAGVEILCSDKTGTLTKNKLSLSEPYTVAGVEPDDLMLTACLAASRKKKGIDAIDKAFLKSLRYYPRAKSVLSKYQVEEFTPFDPVSKKVTAIVISPQGERITCVKGAPLFVLSTVSADHPIPEDIETDYKNKVAEFATRGFRSLGVARKREGGSWEILGIMPCMDPPRFDTARTINEAKRMGLSIKMLTGDAVGIARETSRQLGLGTNVYNAERLGLGGGGDMSGSDIYDFVEAADGFAEVFPQHKYNVVEILQQRGYLVGMTGDGVNDAPSLKKADTGIAVEGASDAARSAADIVFLAPGLGAIIDALKTSRQIFHRMYAYVVYRIALSIHLEIYLGLWIAIMNRSLNIELVVFIAIFADIATLAIAYDNAPYSMSPVKWNLPKLWGMSVLLGIVLAIGTWITVTTMYAQGEDGGIVQNFGNMDEVLFLQISLTENWLIFITRANGPFWSSIPSWQLSGAILIVDIVATCFCIWGWFEHGEQTSIVAVVRIWVFSFGVFCIMGGVYYMLQDSVGFDNLMHGKSIKGSQKQRSLEDFVVSLQRVSTQHEKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z409</accession>
    <name>A0ABR3Z409_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000073">
        <property type="protein sequence ID" value="KAL1895371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="185" mass="20976" checksum="99B600F838FA0DB8" modified="2025-10-08" version="1">MAYPPKPDGAYLPMPPARSHSPTEPTFWSPPWLLNQAAHQTVTPPRYPPYSTTPPRQPTPQACMAFPPPPRHMHYHPHHHTYQQRYVPCCGIFVSPAPTPPNNVVVQAEVREVPRWDAQPRHTYKLTLGPSTAVDYLVTAMGAQTAHDIRVHLSPGHTMPLSELRGRHDMGIMRRPGVWFEVIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4C2</accession>
    <name>A0ABR3Z4C2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Small glutamine-rich tetratricopeptide repeat-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">sgt2</name>
        <name evidence="7" type="ORF">Cpir12675_003378</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SGT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000079">
        <property type="protein sequence ID" value="KAL1895106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.420">
        <property type="entry name" value="Immunoglobulin FC, subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047150">
        <property type="entry name" value="SGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032374">
        <property type="entry name" value="SGTA_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45831">
        <property type="entry name" value="LD24721P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45831:SF2">
        <property type="entry name" value="LD24721P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16546">
        <property type="entry name" value="SGTA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 4" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="SGTA homodimerisation" evidence="6">
        <location>
            <begin position="5"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="114"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="228"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="362" mass="36361" checksum="84C1462CB043FE1A" modified="2025-10-08" version="1">MSLTSKQRLALAICDYLNTSTTDGTLAADEAENIEIAVNCIADSFKVDPTDAAGVRAATGPQTLLQIFTVYESLRQAKEKTGSPTGNIAAAAAAAAAASSSSTTPLSAEDKAAAESLKSKGNAAMAVKDYASAISLYSQALELHPSNAIYLSNRAAAHSAAKDHAAAKTDAQAAVALDPKYTKGWSRLGLARFALGDARGAMEAYAKGIEYEGNGGSDAMKKGFETAKRRVGEQEGDSSADLATREAPVSASAGAESGAGAGAGGLPDMASMFGGGAGGMPDFGSIMSNPMFQSMAQNLMSNPELMGNLMSNPRLRSMADNMSTGGGMPDVSALMSDPSLAEMAKNLMGGGAGAGAGAGGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4C4</accession>
    <name>A0ABR3Z4C4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">U2 snRNP component prp10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">prp10</name>
        <name evidence="11" type="ORF">Cpir12675_003582</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SF3B1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000087">
        <property type="protein sequence ID" value="KAL1894643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054573">
        <property type="entry name" value="PP2A/SF3B1-like_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015016">
        <property type="entry name" value="SF3b_su1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038737">
        <property type="entry name" value="SF3b_su1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12097">
        <property type="entry name" value="SPLICING FACTOR 3B, SUBUNIT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22646">
        <property type="entry name" value="PPP2R1A-like_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08920">
        <property type="entry name" value="SF3b1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Splicing factor 3B subunit 1" evidence="9">
        <location>
            <begin position="202"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatase PP2A regulatory subunit A/Splicing factor 3B subunit 1-like HEAT repeat" evidence="10">
        <location>
            <begin position="977"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="156"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="184"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="214"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="257"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF22646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1894643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1192" mass="133293" checksum="5AE35DF77E088AAB" modified="2025-10-08" version="1">MSDSDFETVRKLQAERNATAAAKNIGSSRFDQTSQRASTKQNLTEAGDSELYDTSDKFKGYNTSIAVFDDDEEMANDGADTRRNLTGQYTASRDIIDEFARGDGVEEDDVLAGKGERTNRIADRETDYQKRRFDRALTPTRVDPFAEGNGTNYRDVMEVRELEREEERVRKAIEDKQREAALNGNGNEEQATLTDGQGDTVRKRRQRWDVAEPTKTTDSATSETEAAAAEAKPKRSRWDQAPAPEAAPMKRSRWDQAPTAGGATSTTTPDVVPAPVLPTDIRNHVYTDEELDAMLPGEDQGYKVLEPPPGYAPIRVPTHRAQLPQPASGFTMQDPETVRLSGKSRPAQIPGVGDLQFFKPEDMVYFGKLADGADENTLSVDELKERKIMRLLLKVKNGTPPMRKTALRQLTDNARVLGAGPLFDQILPLLMEKTLEDQERHLLVKVIDRILYKLDDMVRPYVHKILVVIEPLLIDQDYYARVEGREIISNLSKAAGLATMISTMRPDIDHVDEYVRNTTARAFAVVASALGIPALLPFLRAVCRSKKSWQARHTGVKIVQQIPILMGCAILPHLKGLVECIGPNLNDDQTKVRTVTSLAIAALAEAANPYGIESFDDILNPLWTGARKQRGKGLAGFLKAVGYIIPLMDEEYANYYTSQIMEILLREFSSPDEEMKKVVLKVVSQCANTEGVTAGYLKEHVLDEFFKSFWVRRMALDKRNYRQVVETTVDIGQKVGSGEILERIVINLKDESEPYRKMTVETVEKVVASLGAADVGERLEERLIDGILYAFQEQTVEDVVMLNGFGSVVNALGMRCKPYIPQIVSTILWRLNHKSPTVRQQAADLISRIAIVMKQCGEDALMGKLGVVLYEYLGEEYPEVLGSILGALRSIVNVVGIAQMQPPIRDLLPRLTPILRNRHEKVQENTIDLVGRIADRGPESVNAREWMRICFELLDMLKAHKKGIRRAANNTFGFIAKAIGPQDVLATLLNNLRVQERQSRVNTAVAIAIVAETCAPFTVLPALMNEYRVPELNVQNGVLKSLSFLFEYIGEMAKDYVYAVTPLLEDALIDRDQVHRQTAASVVKHIALGVVGLGCEDAMVHLLNLLYPNLFETSPHVIDRIIEAIEAIRMAIGPGMMLNYVWAGLFHPARKVRQPYWRLYNDAYVYGADAMVPYYPNLDDELLDRPELAIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4L5</accession>
    <name>A0ABR3Z4L5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">WD repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_003345</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000077">
        <property type="protein sequence ID" value="KAL1895162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF0">
        <property type="entry name" value="NOTCHLESS PROTEIN HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="78"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="119"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="274"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="314"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1895162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="397" mass="43667" checksum="4B64B11E1DB10241" modified="2025-10-08" version="1">MSMTTNTNNFFQTDATHAKNDRQLAKSSNVFGNPIKLKSKVLALISDPSAPLSSVFVAESASKVRRVDIETGSVSKSYSGPTAPVTCIAATKNIIAAGSWDKAIYQWDIATSKPIGKPLLGHTDFVKALTWAKLDGVDVLVSGGADRKLIVWNAQTGAQLHAIQDSSIAMGSLQHLVVDPVLTTASEAVVVSAGSDPHIRRWRIRLTSYEKIHEQHYGTTNLEERPTICVHETGVYRLHFATASGDDELDLWTASADGTAKCLSRTRNFAPDDVITHGDHVRAVAVTELWVITAGRDEDIKIWDKASGKLAYVLYGHYDEVTDLLLITDPRDLSQKVCSASIDGTVRFWPLKRKELDQLVEEMHKDITTEAAEENQEEKELLTREEEAELAALMEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5B9</accession>
    <name>A0ABR3Z5B9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Polyadenylate-binding protein</fullName>
            <shortName evidence="10">PABP</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">PAB1</name>
        <name evidence="14" type="ORF">Cpir12675_003091</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and regulates mRNA decay through translation termination-coupled poly(A) shortening, probably mediated by PAN.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the polyadenylate-binding protein type-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000068">
        <property type="protein sequence ID" value="KAL1895758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12378">
        <property type="entry name" value="RRM1_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12379">
        <property type="entry name" value="RRM2_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12380">
        <property type="entry name" value="RRM3_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.10">
        <property type="entry name" value="c-terminal domain of poly(a) binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036053">
        <property type="entry name" value="PABP-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006515">
        <property type="entry name" value="PABP_1234"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002004">
        <property type="entry name" value="PABP_HYD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034364">
        <property type="entry name" value="PABP_RRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045305">
        <property type="entry name" value="RRM2_I_PABPs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01628">
        <property type="entry name" value="PABP-1234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24012">
        <property type="entry name" value="RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00658">
        <property type="entry name" value="MLLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00517">
        <property type="entry name" value="PolyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63570">
        <property type="entry name" value="PABC (PABP) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51309">
        <property type="entry name" value="PABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="7 9 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RRM" evidence="12">
        <location>
            <begin position="52"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="12">
        <location>
            <begin position="140"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="12">
        <location>
            <begin position="233"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="12">
        <location>
            <begin position="336"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="PABC" evidence="13">
        <location>
            <begin position="668"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="16"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="370"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="632"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="375"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="390"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="427"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="636"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1895758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="760" mass="83088" checksum="E47E1DC2BB528B99" modified="2025-10-08" version="1">MASSVDQITNAMDNASIAEKAPATSPVAEAPAAETDSSAAPTTSSAHPQNSASLYVGELDPSVTEAMLFELFSQIGSVASIRVCRDAVTRRSLGYAYVNYNNTADGEKALDELNYTLIKGRPCRIMWSQRDPALRKTGQGNVFIKNLDVAIDNKALHDTFAAFGNILSCKVAQDEHGVSKGYGFVHYETDEAAQQAIKHVNGMLLNDKKVYVGPHIPKKDRQSKFDEMKANFTNVYVKNIQLDVTDEEFRELFAQFGDVTSSSLARDVEGKNRGFGFVNFTTHESAFKAVNDLNNKDFRGQELYVGRAQKKHEREEELRKSYEAARLEKQNKYQGVNLYIKNLNDDVDDEKLRFMFSEFGPITSAKVMREVVGESSEEEDKKEDSEEVNEEAKEEIKEEIKEEIKEEDTKEEVMKSEGEEAVAASAEDDKSDIKKGERKLGKSKGFGFVCFQNPDDATKAVTEMNQRMIEGKPLYVALAQRKEVRKSQLEASIQARNQLRMQQVAAGGAMGQGFMAPQMYYPGGAQQPGFIPQGGRGMPYGQPGMPMPNGGRPGQFPAGFPQQGGRGMPGQMPPNMYVGQFPPNGPYPGGNPMYMQMPGGGRGSVPPGRSPMQGMPVNMASGPGMAGFPPNARPQGGMGRGMGRGGQPAGNFPPAGRQAPSARPEGGISPLQAQVSAIPDMAQQKQMLGEMIFPKIQAVQPELAGKITGMLLEMENNELIRLIEDEVALKAKVDEAMAVYDEYLKAQTGDEKKEEPTAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z685</accession>
    <name>A0ABR3Z685_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003058</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000066">
        <property type="protein sequence ID" value="KAL1895835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="77" mass="8614" checksum="F061C8409A0F13CE" modified="2025-10-08" version="1" fragment="single">MARLDSFIWVRIQLKAFTFLGMKYNSLAYGMSLPLSITISLWSWGFKLLAISAVVVGIPLVVVLNELTSLVAKHRFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z699</accession>
    <name>A0ABR3Z699_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Superkiller protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SKI3</name>
        <name evidence="5" type="ORF">Cpir12675_003033</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000066">
        <property type="protein sequence ID" value="KAL1895811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039226">
        <property type="entry name" value="Ski3/TTC37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040962">
        <property type="entry name" value="TPR_22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15704">
        <property type="entry name" value="SUPERKILLER 3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15704:SF7">
        <property type="entry name" value="SUPERKILLER COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18833">
        <property type="entry name" value="TPR_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="37"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="458"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="656"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="985"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="319"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="319"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1428" mass="159699" checksum="C1CA79604E657B2D" modified="2025-10-08" version="1">MATKAQLKALNELIKKEQYMQAISQAREIIARDGNQANAHLLLGFALEKTEQFDEAEAAYKTAALLVPKLPAAWQGMCKLAERQGAKRLGLFKEALESLIPIFADAEEYPKAREMLERYMGLARNSDNKMDYVEALELTCPDNAAYPSLEGLMERPIVTYDKMITIIETEEKKTINRLIGERRTRLGAVFKTVSQEIKCEVFAQSKREHYLRQAINWCSEDDVRRSYEERLFQHCLEKLTVLKGGPEKDVAREKVLECANGMVVVKHPCRLGWEIALDWQDHKELTDYDVNILREYCRFFPDTDLAKVITGFLTSQLSPFPPEKTNPSPQPKREDYGDSSSSDEDNGGVSTLVIPTTEADRVVIMTNGIASSESLLAYRLVGAYYQYLEEWEMCAELMRKAIRYAATETGRCGMSFLETIDTYRIFLGTALVYYQSPRNHPEAMKLFEAVMDRDPKSTAAMIGTGLIFEEEEEFEKASDFLTRALKCGPTNIKVLSELGWVRAMMGQYDLAEVELRHCLELFQNEKRKDLTNELEAQVQYRIGFCIWHRDPSFAARESRKGAYSYFLAALKSDLSHAPSYTILGLYYADYAGDKKRARRCFQKALELSANEVVSAERLAHSYADDRDWEKVELIARRTVESGKVKPLPGSKRAGISWPFAAIGTACLSKHEYPEAIASFQIALRISPKDYHSWVSLGEGYYRSGRHVAAIKAITHAQSLEAEKSAGELGDTWFTQYLLANIKRELGQYDSAIELYREIYKTHTDEHGIINSLLQTLVDAALDAIEKALFGRAAQLARDVIELGKTVTPLVDKSFNFWKSMGDACSVFASVKSRIGEFPIANIGHIVNTHVATKESDNLFSEYDHINAEQLPVSDKGEPLLKCLHFMIVCQKRAIYVSASDAHAQAVAYYNLGWAEYKAHTCLPLQDRGKPSKFQKAAVRAFKRAIELEAKNSEFWNALGVVTSQINPRVAQHAFVRSLYLDERNSATWVNLGTLALMNNDLETASAAFTRAQSNDPDYANAWMGHGYIYKLLDDEDEFRGQAKHAMSLSTSSNLATRQQFSTLMFDHILKTPDSKLDVSVLVETLFALGQVKALDPDELMYTHMYTLIQERLYDHARAVQSLDLLCSTVEAQFEATEDPELLGRFVIAKADLARSYLASQDYENAIEAGEMAISLTDEVSEQELTTEQRSKARLSAHLTVGLAHYFNQDVESAVGNLQYALEETNGSPDAVCLLAQVLWATGTAENRDLACDKLFGVVNAVSDHVPSRLLLAVISVLGEDWELLAAVVADLNVMRMTAGFDEAMYKDIGNALAAIEALKPGRTLDDVKEQMQTDIMLHPSLPHGWIKLSEIVSSDATQLAQASVSVALKGVPPRGNLCAKDVALAYASTKNAADAQLAVSMAPWVMDGWQSLAEAVVRGREKTQAATM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6H7</accession>
    <name>A0ABR3Z6H7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ubiquitin-conjugating enzyme E2 4</fullName>
            <ecNumber evidence="6">1.3.8.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">UBC4</name>
        <name evidence="6" type="ORF">Cpir12675_002872</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.8.6" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000061">
        <property type="protein sequence ID" value="KAL1896226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004361">
        <property type="term" value="F:glutaryl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23792">
        <property type="entry name" value="UBCc_UBE2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="5">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="3">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1896226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="147" mass="16563" checksum="F3F4072E7652071B" modified="2025-10-08" version="1">MALKRINKELADLGRDPPSQCSAGPANDDLFHWQATIMGPTDSPYADGVFFLDIHFPTDYPFKPPKVSFITKIYHPNINSSGSICLDILRDQWSPALTISKVLLSICSMLTDPNPDDPLVPEIAHLYKTDRARYEANARERTRKYAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9M0</accession>
    <name>A0ABR3Z9M0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Threonine aspartase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000053">
        <property type="protein sequence ID" value="KAL1896912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04514">
        <property type="entry name" value="Taspase1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.30">
        <property type="entry name" value="(Glycosyl)asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000246">
        <property type="entry name" value="Peptidase_T2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037464">
        <property type="entry name" value="Taspase1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188">
        <property type="entry name" value="L-ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188:SF8">
        <property type="entry name" value="THREONINE ASPARTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01112">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="278"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="506" mass="54379" checksum="BE65ED123A47820D" modified="2025-10-08" version="1">MSTYGSEPSYEDKGPPPFYPKKPVMAIFVHAGAGYHSTQNENLHLAVCRDACNIAMTILKVGGTAVEAAAAAVASLEDSELTNAGFGSNLTMEGRVEADATVVDHLGRSGACGAVPHVKNPVLLAKMIMETSQIPLSLRRVPPNLLVGKGAASFAYTHGMPLLRNELLVSQGSRERFIRWRRELQRAAYMVKLKLEENNESLSIVDAHYHSLPITMPQSAPYQIPSPVEQEHSTPPTTKPRLFCPPKKRERTVPVRDSESPGPASRPSSKTEHGVPISTQSPRSPSSQLSSKRHCSGTDRAPSDTHIHMEDSVSSMKEDDIVDTVGAIAIDCLGNIAAAASSGGIGMKHRGRVGPAALVGVGAAVIPKHTNDEDGTSIATITSGTGEHMSTTLASQKCAERMYQGTRQNEQGRDVAEDDEDCIMESFIKQDFMNHPGVLYSPAPAAIGILAVKQTNNGVYFYFSHNTDSFAIASMAGDDEEPLCVMSRRRAKSLNLVARGARRVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA15</accession>
    <name>A0ABR3ZA15_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA repair protein rad52</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RAD52</name>
        <name evidence="6" type="ORF">Cpir12675_002357</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RAD52 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000045">
        <property type="protein sequence ID" value="KAL1897501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.80">
        <property type="entry name" value="DNA repair protein Rad52/59/22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004585">
        <property type="entry name" value="DNA_recomb/repair_Rad52"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041247">
        <property type="entry name" value="Rad52_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007232">
        <property type="entry name" value="Rad52_Rad59_Rad22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042525">
        <property type="entry name" value="Rad52_Rad59_Rad22_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00607">
        <property type="entry name" value="rad52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12132">
        <property type="entry name" value="DNA REPAIR AND RECOMBINATION PROTEIN RAD52, RAD59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12132:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD52 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04098">
        <property type="entry name" value="Rad52_Rad22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="203"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="283"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="421"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="512"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="206"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="296"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="308"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="323"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="352"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="467"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="541"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1897501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="597" mass="63768" checksum="A9975D21B232E9C5" modified="2025-10-08" version="1">MPATGDQHQVGIVNPFEEVQPRVSVYTADEIALLQYRLDKQLGPEYISNRQGPGGGRVHYLAADKVINLANEVLGFNGWSSSIQNIQVDFVDENPQTARVSLGLSVIMRVTLRDGTFHEDVGYGHIENAKGKAAAFEKAKKEGTTDALKRALRNFGNVLGNCIYDKEYLSKVTKVKHMPAKFDEQNLYRHGDRNRLNRIEAASAASHPQITTHVTAPSRPSSVPPGGLKSAPTAPIQQITAVANGVQSRSASPAPVIDSIDDLDSLMDDIDDADLCMAEEGDPDEIILPGTTDMLNGDNQNSSGGSNLALQQPNKQAYQPAAPQTPIPNSRPIPPKPNGNGAAAGRVMPSTRAPQFNQNPNSNGQAQNGPGSGHGPGPPKPPTGNEPVAFFSARAFSQLPETTINNPASIPVAQCIFNPKAESPSIRKTPGVDHTSSKPVARNLKHVPPASSQKEQITIGPGPGPGPAQQQQYMQQAAQSPSLQRCMNNAPPRNGANVVNPHLDQTRRIGAPMAANASPLGNRGQYKPPKMMKRLPPGAPQYPQLQHQHQQYNQQNGGGSNNGSDMTERQALSEVTNNNPVLGGGPIAPDNKRPRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAC4</accession>
    <name>A0ABR3ZAC4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein-lysine N-methyltransferase EFM3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002379</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000046">
        <property type="protein sequence ID" value="KAL1897275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF130">
        <property type="entry name" value="PROTEIN-LYSINE N-METHYLTRANSFERASE EEF2KMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1897275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="338" mass="37997" checksum="37835243A133E7BA" modified="2025-10-08" version="1">MDQNNSSFQIQRFCRQYFQLERELDFPTAEYLRDEQVQRKISFCINDPLRSHSGPPPRYKLRAIKELVSRIEASINDWDKYGVNEDIMEALAEMMATPLSSQDVEVQKRSYVTYHLSELKNAAQGPEPTITLLESRSLISQAGTTGLRTWEAALHLGNYLCHNDSDIQGQSILELGAGTGYLSILAMKHLGAQRVIATDGSDEVINLLSDNFYLNGLQENRGLAATALLWGHSIPKPEETEWGRLSPIDTVIGADITYDQRVIPSLVATITELRVHFPDLKIIISATQRNEETFQTFVGVCRNSGFNVEFMTYAGTLPAQQTGPFYNTTVPIHIVRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB00</accession>
    <name>A0ABR3ZB00_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002176</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000039">
        <property type="protein sequence ID" value="KAL1897831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024222">
        <property type="entry name" value="Ten1_fungal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12658">
        <property type="entry name" value="Ten1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1897831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="130" mass="14463" checksum="D5CF08ED177AF55A" modified="2025-10-08" version="1">MNSLPEASTLHLLSGLPNLKVGDKVRFLGCVTAYTFETATLTIEHDYPKGNQVQASVDIQLHVDDLQASAVDIGTWNNVIGYITWIKHPSKRLDYTSVGVHALAIWPGGSFRLDTYERLVSEPDVVDLYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBR8</accession>
    <name>A0ABR3ZBR8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7871 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000041">
        <property type="protein sequence ID" value="KAL1897755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057193">
        <property type="entry name" value="DUF7871"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40620">
        <property type="entry name" value="RESISTANCE PROTEIN CRD2, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G04318)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40620:SF1">
        <property type="entry name" value="RESISTANCE PROTEIN CRD2, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G04318)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25277">
        <property type="entry name" value="DUF7871"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7871" evidence="1">
        <location>
            <begin position="4"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="107" mass="10942" checksum="E37E416B7CCA860C" modified="2025-10-08" version="1">MSSKPSTCCASGNSCVCAQKATCSCGKTSALACTCEKSASENTITGARCACRARPAGQCTCDRASVENAHPKGPTCSCGLRSQDACTCEKAADGGFNPNEIDFTTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBW4</accession>
    <name>A0ABR3ZBW4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_002213</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000040">
        <property type="protein sequence ID" value="KAL1897787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024766">
        <property type="entry name" value="Znf_RING_H2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15710">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PRAJA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15710:SF243">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PRAJA-2 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12678">
        <property type="entry name" value="zf-rbx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="134"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1897787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="206" mass="22693" checksum="EFA031D5FC09913C" modified="2025-10-08" version="1">MSSQYEIEHSIKPQAKPQGRRPDMSSFDALLDQVSTSGARTSASAVFSAQEHHNPHATPTPVDMAALYRLVQDQMASLASTAPSTENRTLLESLMAELDASIADPPTEVCGLGQDFLDGLERVDRGRVGVEETCPICAEKHRDDPYCLVVELPCHKSHRFDLECVAPWLQSKGSCPLCRTDFTKKKEVVRVEDSEEEDDDPAGMYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCI0</accession>
    <name>A0ABR3ZCI0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="4">PPIase</shortName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CSR1_2</name>
        <name evidence="6" type="ORF">Cpir12675_002114</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000038">
        <property type="protein sequence ID" value="KAL1898027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF385">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="5">
        <location>
            <begin position="56"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1898027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="220" mass="24263" checksum="1FA235FB598A9496" modified="2025-10-08" version="1">MSQQEPIKSSGDLKVYFDMEWLGPTQENGVFASNEQGMSNKFLLSVPSRIKMHESLAMLDIPDTQTGRIIFNLFKDVVPETCENFRVLCTDEKKDQGLRYAGSTFHRIIPQFMIQGGDFTRGNGTGGKSIYGSTFNDENFKLKHTKPGLLSMANAGPNTNGSQFFITTAVTSWLDGKHVVFGEVADEESMKIVRAIEATGSSSGTVKYKKRPTIVACGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCI3</accession>
    <name>A0ABR3ZCI3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Aromatic/aminoadipate aminotransferase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ARO8_1</name>
        <name evidence="7" type="ORF">Cpir12675_001866</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000032">
        <property type="protein sequence ID" value="KAL1898403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050859">
        <property type="entry name" value="Class-I_PLP-dep_aminotransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42790">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42790:SF21">
        <property type="entry name" value="AROMATIC_AMINOADIPATE AMINOTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="6">
        <location>
            <begin position="179"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="526" mass="58805" checksum="063086A50491259F" modified="2025-10-08" version="1">MTAHSSADTTTTQYSDALQAIKARRAAANHPKAGIAAYSESDYFKGPQTGKPMAKRWDHYLSAESKHRQPCMLKKAAQHLKKPDIISLGGGLPSSEYFPFSEMKLRVNMPDAFTETGPSSQTTMGKHDMSVLDAEYDLAIALNYTQASGSFQFMRWITEHTELLYNPPYADWGCSETIGSTSALEIALRMLCDKNRKDTIITEEFSFASAIETMTPMGLAIAGAKVDGEGLDSESLDEILSSWDEQARGSRKPHVLYTVPSGQNPTGATQSLERRLAVYSVCQKHDVFILEDEPYYFLQMPAYKTKAERDSTPTSSPWSLDAFLSSLVPTFVSIDIDGRVMRMDSFSKVLAPGSRMGWITAPAQIIERYIRHAEVATQAPSGFSQAALYKLLDETWGHETYLKWLQHIQHEYTHRRNVLLDACEEFMPKSVTSWVPPSAGMFLWIKVDHTQHPEIGKRSLEEIEESIFLDCVDNGVLVASGSWFHAETPKPLPGLYFRATFAAASEERMSMAVKRLSEAIKKSFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD97</accession>
    <name>A0ABR3ZD97_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002135</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000038">
        <property type="protein sequence ID" value="KAL1898046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046499576" evidence="2">
        <location>
            <begin position="20"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="210"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="370" mass="37338" checksum="A0A69A1B077EA644" modified="2025-10-08" version="1">MSFTSKLVILATLLAFAESRFGQEQIPVSAISSLTEFGSPGQAGSLSGEVPGVLLASSNPCDKLVLADKIVDTLGDDPQVIDAAKQLVAAERNFNPSNTKIDSLCASADLPATEALRGILPLVDPDTTGSDVENENSKTSLTSPFPADGLSIADIAIAQGFSNFTSVEAGAQNTGNNNGKTGNNGGQPKNNGSAADIVAKPTTLSTVTRTATPTPTAGGNTGNTGNTGNTGNTGNTGNTGNTGNAGNTGNTDNTTGDGDSTSLPSTAVGGGAADFGSCDPTIRREGGLGGRPATEFTFQANDPKIEAIQQEALNPNIITNRICDELTNQCGANDEAKTICQAAKAQVAAIGSPADRSDQTVTVWNSALGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDE0</accession>
    <name>A0ABR3ZDE0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">4a-hydroxytetrahydrobiopterin dehydratase</fullName>
            <ecNumber evidence="3">4.2.1.96</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">4-alpha-hydroxy-tetrahydropterin dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_002302</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin = (6R)-L-erythro-6,7-dihydrobiopterin + H2O</text>
            <dbReference type="Rhea" id="RHEA:11920"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15642"/>
            <dbReference type="ChEBI" id="CHEBI:43120"/>
            <dbReference type="EC" id="4.2.1.96"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pterin-4-alpha-carbinolamine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.96" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000044">
        <property type="protein sequence ID" value="KAL1897514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.20">
        <property type="entry name" value="Transcriptional coactivator/pterin dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036428">
        <property type="entry name" value="PCD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001533">
        <property type="entry name" value="Pterin_deHydtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12599">
        <property type="entry name" value="PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12599:SF0">
        <property type="entry name" value="PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01329">
        <property type="entry name" value="Pterin_4a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55248">
        <property type="entry name" value="PCD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1897514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="86" mass="9723" checksum="15E5944F416844BD" modified="2025-10-08" version="1">MSTPTTLQPIFAEGQDAEGLRVQVRHLLEDGGDAGRWHLSADRSGVERAFKFKTFGKTWDFMTAVSLQCKLRNHHPEWSNVRPSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEE6</accession>
    <name>A0ABR3ZEE6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NEDD8-activating enzyme E1 regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_001663</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Protein modification; protein neddylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000027">
        <property type="protein sequence ID" value="KAL1899003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030667">
        <property type="entry name" value="APP-BP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF29">
        <property type="entry name" value="NEDD8-ACTIVATING ENZYME E1 REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039099">
        <property type="entry name" value="APP-BP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="6">
        <location>
            <begin position="24"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR039099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="556" mass="61303" checksum="F784751E5A4139DF" modified="2025-10-08" version="1">MNTMESPSIQPPSLHGPSEKERKYDRQLRLWAASGQAALEDARVLLLNSGGGTVGVEALKNLVLPGIGHFTIYDEATVTDVDLGVNFFLDEKSLGRSRAECCTNFLLELNPEVRGNWYPKTEDQDTQLAPGALENKRVRLSNSPSGCLGLQNLLQSLPAFTIVLYALPINPEYQDIIEAYGKKHRIPIFSVHSAGFYAYFNIHLSGPLLITETHPDPATTTDLRLLSPWAALIDFADNITKDLESQDHHTHGHVPYVAILLHYLQKWKDNHEGSYPLTFSQKNEFRKIVAAAMRTDNPEGGEENFEEAVAAVMRNLTKPSLPPNLKQIFDLLDSDKIDCSSSTIWAIAAAIKSFYNKHNCLPVSGGLPDMKAQSDIYISLQNIYKAKAKADFEEVLAILRTSLEGKCVTEEDVALFCKNSAFAKLIKPQTVSPETLKEILEKEAANDEISEDTGAPLSLLPIYLALKTTSYVATSSAKGIMSSINEITPNVKNRERFQAIAEEVARAGGSELHNISAAVGGMIAQEMIKVITRQYIPINNTCIFDGVTSRCQVINI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEL7</accession>
    <name>A0ABR3ZEL7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA-directed RNA polymerase core subunit rpc10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RPC10</name>
        <name evidence="7" type="ORF">Cpir12675_001613</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000026">
        <property type="protein sequence ID" value="KAL1899056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.30">
        <property type="entry name" value="RNA polymerase ii, chain L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006591">
        <property type="entry name" value="RNAP_P/RPABC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039747">
        <property type="entry name" value="RPABC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029040">
        <property type="entry name" value="RPABC4/Spt4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12056">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12056:SF2">
        <property type="entry name" value="GEO11084P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03604">
        <property type="entry name" value="Zn_ribbon_RPAB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00659">
        <property type="entry name" value="RPOLCX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63393">
        <property type="entry name" value="RNA polymerase subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="74" mass="8175" checksum="05D7EFFB49C21C4F" modified="2025-10-08" version="1">MSSREQYQIPSGSGAGIGSGSTKFEGPAKLNYICGDCGLNSTQHQTVPFLRCKECGCRILYKPRTKRMVQFEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEZ3</accession>
    <name>A0ABR3ZEZ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tetratricopeptide repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_001541</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000025">
        <property type="protein sequence ID" value="KAL1899258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051240">
        <property type="entry name" value="Mito_RNA-Proc/Resp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057585">
        <property type="entry name" value="TPR_dom_fungi"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47933">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47933:SF11">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24603">
        <property type="entry name" value="TPR_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="391"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="Tetratricopeptide repeat" evidence="3">
        <location>
            <begin position="509"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="876"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="911"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="1125"/>
            <end position="1159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1899258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1170" mass="128957" checksum="E4A9322D87800689" modified="2025-10-08" version="1">MPTIYSSLYQQFIRQGLTKSVTHGYAQSVVAATHPHLLNSQNRPSFAKRNSNRVSRLHTLQLKNAFHTERQTSGLATTHDHIHDRGLGHGGLDAYFEALKQKRDETAESSEEALEEWSQFEFQKQIEWKPSPASILLGEARPVIDDDYAIIDENGDDVNTPPGRYSPADEAALAHIDAALHREIDARSRQESLGEVSDHSAAASPKAPFSVAASGIQSCHDQRSRSPARPRAPLVDAQAVAYANHLLGLSKAGRYLEIPAVFEAMLVAKIRPLASAYNALLMAAMHIPTDKSEVLSKSLEVYTDMLRRRVAPDNDTYDILVGLLCTRSLEVSRKKAELETKRVRFGGMEKAGKFMFASHELEEAILSEDDRLDLAIKLFTESLGTCRASYSSETYNQLISACAASGRLSDMLKAFEHMESQNITPYASMFPQMIIAYGSNGDLTSAVDCYNEYKQLAIRKDAGDETLVGRQDSEVYAAVIYSYIVANKLESAIVFYRKIVELHGTDGAQIQDVLINSGLVKAFVDRGSFDQALEWAQGIKSATRGDATAKIALAAADRNERNTALAAFGNIPGSYGKIVAPAAAMLALSIRSGDVSSAMKYWQILSHPDIKATTDMIEPTAMFAVAMIGSGQVAEGLAQAELMFERIKAAQSESRPDLADEIEEGMHFIAHYMRSRGVVDTRNVQPVSLMPNAPVQLVAPSATSSFEDSFDPYAHNTDFKGSALISEELEGAHGRRAPRMAKAMTQFYNIRRAGRHPRYITYAKLISAASREGNMGLCLEIMNMAHTDIPLQSQYATVRYGWSSILDAMVGASLYIGDRLGAEEYHQKLLEIGATPSANTYGLYITTLKESTKTFDEASEAVKIFHRAKSEGVEPSSFLYNALIGKLGKARRIDDCLLYFSEMRALGIKPTSVTYGTIVNALCRVSDEKFAEELFDEMESMPNYKARPAPYNSMMQFFLTTKHNKAKVLAYYDRMLSKGIVPTSHTYKLLIDTHATLDPLDFSSAEAVLDDMRAAGVKPEPIHYASLIHARGCVMHDVDGARAVFDSVMADLSVASNASLFQSLFEGLVANHRVAETEPLLGMMKKRQVALTPYIANTLIHGWAAAKKIERARAIFEAVGYDKCEPSTYEAMTRAYLAVEKRDEAREIVNEMMSRGYPSAVVNKVLELMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG14</accession>
    <name>A0ABR3ZG14_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Peptidase S59 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_001336</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleoporin GLFG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000020">
        <property type="protein sequence ID" value="KAL1899658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1610.10">
        <property type="entry name" value="Peptidase S59, nucleoporin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025574">
        <property type="entry name" value="Nucleoporin_FG_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037665">
        <property type="entry name" value="Nucleoporin_S59-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007230">
        <property type="entry name" value="Nup98_auto-Pept-S59_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036903">
        <property type="entry name" value="Nup98_auto-Pept-S59_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021967">
        <property type="entry name" value="Nup98_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23198:SF6">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP98-NUP96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23198">
        <property type="entry name" value="NUCLEOPORIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04096">
        <property type="entry name" value="Nucleoporin2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13634">
        <property type="entry name" value="Nucleoporin_FG"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12110">
        <property type="entry name" value="Nup96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82215">
        <property type="entry name" value="C-terminal autoproteolytic domain of nucleoporin nup98"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51434">
        <property type="entry name" value="NUP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="5" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="8" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Peptidase S59" evidence="11">
        <location>
            <begin position="886"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="58"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="717"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="782"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1173"/>
            <end position="1193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1288"/>
            <end position="1337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="11"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="370"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="791"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1173"/>
            <end position="1190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1318"/>
            <end position="1331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1899658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1945" mass="203643" checksum="D602CFB95B83A391" modified="2025-10-08" version="1">MSFGGFGGFGQSNNNNQSSGGFGFGTNTNNTSTPGGFGSTNTTSAFGANKSTFGTPASGGGLFGSSNNNNNNNTNNNTTTSGNAFGAFGGNNNTTATSGFGSSSGNSLFSANKPATTGTGFGSTSAGGGLFGGGGTNTSSGFGAVNNPGIGNAGDPPGTNTIPFQAYQEKEGGSSTTTNSFQNILFQDAYKKWSADELRLVDYAQGRRFGNASGGGAFGVNAFGSGTSAFGTSNNTNQTQTPAFGSSISGGGLFGANNTTITTNSTGFGTNNNNTTSAFGSGGGMFGAKPAGTGGLFGGASTTNTPSGGLFGNSNAASSGTPSNAFGSNTGSAFGQTNTPAAGGGLFGNNAAKPATNAFGSAFGSNNATGTTPGAFGQSNTATPGAFGQTNTGTAGGGLFGGATPAANTGAGLFGNNNTTAAASTNAFGATNTTSTTGGGLFCNSNAAKPGGLFGAAQTTTPATGGGLFGNNAANNATTTTNAFGAVNNANSGNTGGGLFGAAKPPTSGGLFGNNAPAATAGGGVFGNAGAANTTTQATGGLFGAAGQTQQKPSLFGQTQTAGTGAFGIQNSQAGGSLFGGAQAGSSLLGQSNLTGNQNVGTGAQGLNASINDVSAYGNASLFAGLSSGEVSNPGPLATPLSTKGKAKKSNVLPMYKLNPASSSRYATPQKRGFGFSYSTYGTPSSPASISGTPSGLGRSLLATSLSRGLSRSLSTNSLRRTYGGEEGSSGTSNGLATNSILTPGAFSSSTTSWYHGGSGSLNSGNKKLIINRDVRSDLFSTPSKDKPLIESSSNPAPVASGSTRKLSKRVSFETNGGVNSDKEEVLSAPKSRVSALANSERGIKASVSMPSLHDSVKGNELAIVHEEEIGSPVPPTPSTGKDSLPGQYWMSPSMKELSSMNRLQRQSVVDFTVGRENVGQVQFKVPVDLSNIDIDDIVDNIVILETRSATVYPIAEKKPPMGRGLNVPARITLEQSWPRGKRDTSDEKRIAKHVDRLRRIVDTEFEEYDSTSGVWVFSVEHFTTYGLDDEDESDADATEFSESTETVLAAPKNQVDLDGECSISPSSDSFGSDPDDTFDFRNKRLALPGTFDSVAATNTRPRVESHLQSFLGVSSVGSGPNQIMLSVEDSDLGDEYAASDGEDMASLTTGKHHAAEHFEDYSSVSWEVMEEDMNNDESEDDDLGDDEEAPGGGVLRARMRALKMSAGPVRVEVTDGDDWMDMLKKTVSPVKRCRAQFRDGNAELMPMDLAAQSGVVDSGEEEHELLGIIGEGRGFATTIDLMNSLFERPSSEKPSSKPKPQPQPRGFVQWPFDRQPKVSNAPTNIPTTTRVRWGPDGTMVMATRPAQKSLQPMNLDDNSIFSIQNRRLPDELSGVRLGRLSAGRAAHLLDNHMRHTKVNILNGVPKASLDIPSLKTMFQDRNTSDTGAAHEKLVWDLASILFDPIQDESFRDRKDKLSAFWTDLVASSCATEAAFSKSLEMKAVASLAGHRVQEACKHLLDGKNFHLATLVSLIGTDETLKNDMRDQLSGWRDAMMLSELSEPIRAIYEMIAGNVCVCEGIKGVPPQDRIESFIISTKFSLDWMQAFGLRLWYATSPNDSLAVAVRKFHDDISQGLEPLPMPWFIKQAIAPLWDDKARDQRQDLLWGLLKLYAGVDIGLECVICPENSQMSPLDWRLSWQLGQALSSVTDLSFGANSETQADSATLSFASQLINEGSWLQVVFVLLHLHNPDSRSKAIRDQLAQNAGSIGIESDDTFITLTQVFKISAAWVWESQALYMRSVMHDAPAEVHCLLRAGALVEAHQRFTEEVAPLAIIERDYKLLSSLLAEFEDRHDTIPNWSLGGDVYQDFLSIITIETKKENVPISLLTKMLSTLPAMQEASVNQDALVTAAVSEMSSILARIVTEVSQDSLLHRVLSIPLTEDGHLKYSIDLSIAYYKGIMTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG37</accession>
    <name>A0ABR3ZG37_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_001476</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDXG' lipolytic enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000023">
        <property type="protein sequence ID" value="KAL1899360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033140">
        <property type="entry name" value="Lipase_GDXG_put_SER_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF19">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01174">
        <property type="entry name" value="LIPASE_GDXG_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="5">
        <location>
            <begin position="152"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="5">
        <location>
            <begin position="345"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="302"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="471"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="662"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="737"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="771"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="850"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1089"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="319"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="480"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="663"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="774"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="871"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="915"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="937"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="949"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1020"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1106"/>
            <end position="1116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1136"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1158"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1179"/>
            <end position="1190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1201"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1232"/>
            <end position="1253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1262"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1351" mass="147901" checksum="62FCD73A96C8E8E3" modified="2025-10-08" version="1">MNSTSVSVAEIPTVIRTFVSHYISKKNSPEKPTSHLRYDQGLNLVRGFIDYSSTHTVEELQSFTSQWVPHPTWVRVQRVTIPSSILDKAAVYLQAELGEEGLAQVGGRNWWQWRLPGSNLDAEWVEMKSDYQDKQERENDDSKDAHQPRRVMFYLHGGAYYFGGVNEHRYQLQRHARKLKARVFAPEYRLAPQFPFPCGLQDALAAYMSLLVSYNPIEIIFAGDSAGGALALSLLVVLRNQNLPLPSGAILLSPWVDLNHSFPSVTADPALDYVPSDGFHHKPSKAWPPPTYEEWEEMCKEAGSSAEIENAGSTKEDQIASTNDPSAQTMPPSHITIVTENEVITVKEQVQMYAPNHLLSHPLVSPIMQPTLGGLPPVMIVTGGAELLRDEQIFIAHKLANPQRYAAPDLTEAQRAQVAQYPPTLVQLQVWDHLCHVATTLSFTEPAKYMFRSIAQFGAWALNVPLDATGPPEDSADVPGTTSSVNEGSVSEKCKQSGNPIGKIGGAGEPLPQFVDSMIRQRVDKNGNIYELASAFTFPFCDPPDYTQVGKVKPVPIKRWLSTRAKYDSKYARIKRDIRKETIEDIRGGFIKHGDGENPPLSALAGRYLLNPVPRKSKLSKITVPHTWSLWGSKHDEHMMQFRRKQREAHEAEEKDMKLNVVTSQDSTDPQSPSASSSVSPFTIVDDETVGIIDSSGALPNTLEEIEPRNTELLDAVSEKQPELLKKEAEKEVEAQSILSGQSSCLSSDTSGSSLGQTRADKFYEAQEAIGINNEESSQDTSLSIPQESELAATPKPPLPPRPSAERVTSDELEIGMTRATDNVAPGAASEEQPGLAKPVEVVRGKLVGKAAWTPPESPVRVRPKVSTTNLPSIDPLSPISPICLPLSRDDPAIPNLSALIPEKPTNPPPEIPKSAQTAKSIRSVKSTKSTNGTTVKSPKSPRSPKSLNRISPTRDILNNYSAPTTAPPQKELPKLPPGQLPKITLLRTQLPPAVNLNPWEASAPPTTALPPLPKMPRTGSDRRDPTSHDLERFPTQVEQPLEGEDDPENVLSLVDSKAPIASIPTKELVPCPGVRKLSSLKSVPPLTVNTVLSTPVPPPKDLEISQDQGHISTMPSIAGVEAFPSNDVSRDKNPENASFTTNNSADRLDPLDGSAAQDGTQGKDSQMDTAQEVESLATVATPQQSTNSWDHLVEVSPPLPEKDLPRSEKVLEAPSPTKSAKPGRKRLWPWSRSSTEKNNATTGPVPSTQQTAGPADPNNPPVYSTLSPESWTNQQSWTRFPAWRSQVDMLIDQRRTREKEKAAKGEVETGVVGKRPMLGGIALPFSLGRKTSTESLRTLHSDEAVEPQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG48</accession>
    <name>A0ABR3ZG48_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">nicotinamidase</fullName>
            <ecNumber evidence="6">3.5.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Nicotinamide deamidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PNC1</name>
        <name evidence="9" type="ORF">Cpir12675_001465</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; nicotinate biosynthesis; nicotinate from nicotinamide: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.19" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000023">
        <property type="protein sequence ID" value="KAL1899349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008936">
        <property type="term" value="F:nicotinamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01011">
        <property type="entry name" value="nicotinamidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052347">
        <property type="entry name" value="Isochorismatase_Nicotinamidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11080:SF2">
        <property type="entry name" value="LD05707P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11080">
        <property type="entry name" value="PYRAZINAMIDASE/NICOTINAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="8">
        <location>
            <begin position="6"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00043224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1899349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="224" mass="24976" checksum="3196010B6B80ED64" modified="2025-10-08" version="1">MLSRPALLVVDFQQDFCPPNGSLAVPDGRAITNTINDLLDLPFTLKIATMDWHPANHKSFASNHQDCTPYVSTTCITNPYNTAESFTTRLWPTHCVQQTPGAELVPEMRSDKFDHIVRKGTVAEVEMYSAFYDPFENPRVSDSGLANYLRERSITHVYIVGLAADYCVKATAIDAQKEGFTTYIVDEGTRPVDSKAWPQIRNQLCKEGISVVSFNGPEVAKLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGG7</accession>
    <name>A0ABR3ZGG7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Endothelin-converting enzyme 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_001561</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000025">
        <property type="protein sequence ID" value="KAL1899277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08662">
        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="entry name" value="Neutral endopeptidase , domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733:SF167">
        <property type="entry name" value="FI17812P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00786">
        <property type="entry name" value="NEPRILYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046656209" description="Endothelin-converting enzyme 1" evidence="8">
        <location>
            <begin position="19"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 N-terminal" evidence="10">
        <location>
            <begin position="61"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 C-terminal" evidence="9">
        <location>
            <begin position="495"/>
            <end position="695"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1899277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="701" mass="78978" checksum="07BDB7D59368B055" modified="2025-10-08" version="1">MRLGAVLAPGLLAHTINAQAGTSTVNDETPLNPGYCNTPSCQRITQEFSSNLAPNYAHLDPCNNFEEMVCGGWRQKHHLKYGEEVIDTVKLIQHNVDNILHELVEGPLPAGIEPNSQDAKNFYKMKAIYDSCMDTETIKSRGIEPLKEVLALIDGAETTKDALLILLKHNTDGLAVVGPQIDDSNPDYIAIGFTGPKNLGLPLQSDFKSKSTLQKYYLIVKKILTALYPETTRETIMNLVILEKKIAMLLPSEEQNHSDTDEYGSMSLEEATKLVPELGLQDIVNTLAPEGVSVDRVIVHHKRYFDALPKLLEKASPDVLKSYFRWHLIVSYQAFIDSDILKPLNDFYDSMLVQDDHKTQCLQYTESSVQNIASRFLVERTLPPAAKTMAGEMVANLTEVYTEKLKAAEWMDSDSADLAIKKLYNMQQKIGYSASSPNITNPDELAHAYRYSVINDNTLFENEVSLRQMKYKLQWEYLGKPLDRDIWQKNPNIANAYYHALGNEIIIPAGIMQFPIFDVEAPAYVSYGSFGSIVGHEMSHAFDSERRYYDENGAYTKTLPWWTPDTDAAFNIRAQCFVDQYSNLVHRKKNKFRAYVDGKITLNENIADTGGLLTSYQAWKKLDAAGKGGEMLPGLEFFNREQLFFVSYVNRLCSKYDVPSGHTFTSSHSPNWARAAGTLANSEDFLRAFNCPVKKPTCKIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGV8</accession>
    <name>A0ABR3ZGV8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="4">PPIase</shortName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CPR2</name>
        <name evidence="7" type="ORF">Cpir12675_001435</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000022">
        <property type="protein sequence ID" value="KAL1899399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0697">Rotamase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="24"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="269" mass="29149" checksum="B3DA1A67C0F67BE3" modified="2025-10-08" version="1">MTGLLFFAQPVEAAMGPKITHKVYFDVTQGGKPLGRIVMGLYGKTVPDTAENFRALATGEKGFGYENSIFHRVIKDFMIQGGDFTNHDGTGGKSIYGRTFPDENFKLTHSKKGVLSMANSGENTNGSQFFITTAITAWLNGRHVVFGEVLEGYDIIEKIQSSPSDPKNNRPIEEVKIAESGELDDVPPEGIEGTVLFADGYGGLADGAMSEADNNAQTPDFKAGLKLESNAGYSAATKIILFVIFVAVAASYVRMRRQSSANAMYYNKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIL2</accession>
    <name>A0ABR3ZIL2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_001056</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000015">
        <property type="protein sequence ID" value="KAL1900057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20353">
        <property type="entry name" value="Rcat_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051628">
        <property type="entry name" value="LUBAC_E3_Ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047546">
        <property type="entry name" value="Rcat_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047544">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770:SF42">
        <property type="entry name" value="FINGER PROTEIN (ZIN), PUTATIVE (AFU_ORTHOLOGUE AFUA_4G03910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770">
        <property type="entry name" value="UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26200">
        <property type="entry name" value="Rcat_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26191">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="417"/>
            <end position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="821" mass="93482" checksum="91D515E8A1D5C1FE" modified="2025-10-08" version="1">MAHENDTNQDAGAPLVPLFANELHTLQTDVLVWVSRYDTLRNLDDQGPVDLQSLKVLVFNWLVDQKITEPDFDTHMGSPLPPKYWSFVSWWQAFTSRSCESLMPGTPEIWKGKMEFLTTIWPAPFTEIIERENWKTRLHNICTGRSRRTKKLKAKPKAKQPPPLIFDKAQVPRPRAPILNMRNMQTCLERLVVMFPNIQVDVFRELLHLYRDEGYSKLAVVADVLIRRRHEVIKGRFREPEDQWQIQWPLNTDKADAVDRNRLGNLGYLRQPLPDVHLKRSPEYRAAVKRLAIKEFPGVTKPEAMAALAGCNLRYLEARRVLAARSNRHWRGHRFHDLIRDRTTLPDDPLLRWEARTGPGVGDSAEPCIESTGSAELDAELFEALVQPILDERYTQKMQQDAESRAAEFQDAVRLGAVVECESCFSSVTHDAVALCSRQGHFVCRICIKQAVSEATFGLAFRSIINLSTGSLRCLAATDVDSQDCDGVISGTGIRGQLRDLDGCLDLLRRFDRRFAEHALLATNLRLLRCPLCDYAEVDDIYLPESEQTPRIRVKTISRGFCIVLCIIWIPFLVSITSLSHLCDIFSRASTTRPSILEDLDVHAAWTRAIRRYHCRNRSLRFQCRDPHCSRTTCLRCHAPWADGHLCSSDEANGSMRMYVDEALTRSIKRECPRCATAFVLARGCNKMTCRCGLTICYVCCADISSNGYQHFCQHFREPGDGTPCKVCDRCNLWQDTGEISKTDGRRLDMNQLRQQAELEWRASQKKKDYGGRKFQRAISNVFGVVDAHNAGEAANPLQLLAEGEYPQLDDIADCLVASLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ01</accession>
    <name>A0ABR3ZJ01_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Oxidation resistance protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">OXR1</name>
        <name evidence="8" type="ORF">Cpir12675_000966</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">May be involved in protection from oxidative damage.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OXR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000013">
        <property type="protein sequence ID" value="KAL1900384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006571">
        <property type="entry name" value="TLDc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354:SF62">
        <property type="entry name" value="MUSTARD, ISOFORM V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354">
        <property type="entry name" value="NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07534">
        <property type="entry name" value="TLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00584">
        <property type="entry name" value="TLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51886">
        <property type="entry name" value="TLDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TLDc" evidence="7">
        <location>
            <begin position="104"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="204"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="36"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="208"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="228"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00037112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="342" mass="37302" checksum="CEDBC7E418D2E3BF" modified="2025-10-08" version="1">MWELLRRFSQDSSHPDPSPSRKFSSIPRSDVDNQDPATSSSPSLYTSPPTTRAPNSRSANSGPKYPLGSHRHAQQRRIPSPFQPPPLDPVELLGYKATTPASARLLSTALAEEIRIMVPERLKLSEHWRIVYSLEQDGASLATLYQKARAYEGQRVGFVLVVRDSEGGTFGGYLSEYPRPSSSYFGNGECFLWRASILAPLPPPPSADTTNAVRSTTIRSPARRDFPSENSDSLVSDASSNKGQGYHTAGSSLSPSRPHTPTDPFESLRFIAFPYSGENDYCINCEAGFLSLGAGGGHYGLWIDNGLERGRSSLCDTFGNQPLSDEGDKFSILGLELWVVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJE5</accession>
    <name>A0ABR3ZJE5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CBM21 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000673</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2440">
        <property type="entry name" value="Carbohydrate binding type-21 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005036">
        <property type="entry name" value="CBM21_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038175">
        <property type="entry name" value="CBM21_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050782">
        <property type="entry name" value="PP1_regulatory_subunit_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12307:SF36">
        <property type="entry name" value="GLYCOGEN-BINDING SUBUNIT 76A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12307">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03370">
        <property type="entry name" value="CBM_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51159">
        <property type="entry name" value="CBM21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBM21" evidence="2">
        <location>
            <begin position="244"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="468"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="513"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="674"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="515"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="530"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="679"/>
            <end position="713"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="745" mass="80697" checksum="B09D5BC4A63291F1" modified="2025-10-08" version="1">MAAATMTMNVTPVHLLAPMTLSIPASLSVRQSPPPVTPGHAIPCGAVISPPESASDSDEDGLEIRGRDRQSLMNLKMSICPQAMEVSPDMISNSNSTKPDGPSFVLSPKRNANEPNVNVSTPRSSSENAIDGTDEETDAEIYKPKMVRKKSGELVRPALRPSSKSRRAISAPGTPTFSKAVHFDSQLEHVRHFLQVDRPAAVSADSSPRENYESETEYPFYDRKTLVEPPFSWEMITTNFPAPSVYRQSQPICLEKVWLSADQKSLVGSVAVANMAFQKLVVCRFTFDYWKTTSEIVADYSCPIVPKMYAQGTDRFTFAIRLSDTANLECKTMYLCMRYSINGTEYWDNNTHLNFQVDFRKKYQKQNGKHAFHGNKTMPVQVHNQPNALPRSSRSNSGANRMNGGAPNTGSSQNSLPRSSHARSKSMPAGVNFEDLGLSSKSPPTNIKATSAASTKASVIQGLLDDEPITIRLKQPQRNGSPDKNENSSGMAFANRYDFGASLSAARMELNPNKMKAKSAKKATSKPDTMPSTNMPATNGSGARSSLASTSYEELVNKYCFFSSKPSGAGTDSKAHRHHQSASAISCQAQVQPAAKVLGHGRCFSHTIPHNYATKSHTSAVSNHDLMPLQEAALRCQQAMLGFPPNRQQALAPAVQAPPPPLPQNRLQQQAGDFVPIDGSVTPPTPSSSNGSSPTITSVSPSSPVSPPTVLSTGLPAAENQSVKNFSNGMHERLPFEQWATALTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJF3</accession>
    <name>A0ABR3ZJF3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">1,4-alpha-glucan-branching enzyme</fullName>
            <ecNumber evidence="4">2.4.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glycogen-branching enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">GLC3</name>
        <name evidence="11" type="ORF">Cpir12675_000726</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Glycogen-branching enzyme participates in the glycogen biosynthetic process along with glycogenin and glycogen synthase. Generates alpha-1,6-glucosidic branches from alpha-1,4-linked glucose chains, to increase solubility of the glycogen polymer.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.</text>
            <dbReference type="EC" id="2.4.1.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.18" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003844">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd11321">
        <property type="entry name" value="AmyAc_bac_euk_BE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02854">
        <property type="entry name" value="E_set_GBE_euk_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006048">
        <property type="entry name" value="A-amylase/branching_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037439">
        <property type="entry name" value="Branching_enzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43651">
        <property type="entry name" value="1,4-ALPHA-GLUCAN-BRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43651:SF3">
        <property type="entry name" value="1,4-ALPHA-GLUCAN-BRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02806">
        <property type="entry name" value="Alpha-amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000463">
        <property type="entry name" value="GlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="10">
        <location>
            <begin position="230"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1900850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="708" mass="80923" checksum="A27934D188A0A4A6" modified="2025-10-08" version="1">MPSATQGTLVEIAPNVTLDLDKVAKDGSGIISLDPYLEHHRDALKRRYSKAQEWLKKLDATEGGVANFAKASPPPTMSGGYERFGFNVDQHNNIVYREWAPNAIQAFLIGDFNGWDRKSHPMKRNDFGVFEITLKAENGQAAIPHNSKLKIAMNLPDGRQIDRLPAWIKYVTQDLSVSPAYDARFWNPPPSEQYKAKNPRPKKPKSLRVYEAHVGISSPEQRVSTFKEFTKNMLPRIRDLGYNTIQLMAIMEHAYYASFGYQVNSFFAASSRFGTPEDLKELIDTAHGMGIVVLLDVVHSHASKNVLDGLNEFDGTDHQYFHGGPKGRHDLWDSRLFNYGQHEVMRFLLSNLHFWMEQYGFDGFRFDGVTSMLYVHHGIGTGFSGDYNEYFGSQVDEEAVVYLMVANALLHKEFPDCITIAEDVSGMPALCVPVDLGGVGFDYRLAMAIPDMWIKILKELSDDQWDMSKICWILTNRRHGEKTIAYAESHDQALVGDKSLMMYLCDAEMYTNMSTLSPLTPVIDRGIALHKMIRLLVHGLGGEGYLNFEGNEFGHPEWLDFPRDGNNNSFWYARRQLNLTEDSHLRYKFLNNFDSAMNKTEDKYGWLGSPQAFVSLKHESDKVIVFERNGHVFVFNFHPTQSYSDYRIGIDDAGVYRMVLQTDLEEFGGHKRLEESTRFFTKPEEWSNRRNYTQVYIPCRTAFVLAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK79</accession>
    <name>A0ABR3ZK79_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Pre-60S factor rei1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">REI1</name>
        <name evidence="11" type="ORF">Cpir12675_000918</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the REI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041661">
        <property type="entry name" value="ZN622/Rei1/Reh1_Znf-C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040025">
        <property type="entry name" value="Znf622/Rei1/Reh1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13182:SF8">
        <property type="entry name" value="CYTOPLASMIC 60S SUBUNIT BIOGENESIS FACTOR ZNF622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13182">
        <property type="entry name" value="ZINC FINGER PROTEIN 622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12756">
        <property type="entry name" value="zf-C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="322"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="437"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="324"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="367"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="443"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1900450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="514" mass="57925" checksum="A5AE769A2A928294" modified="2025-10-08" version="1">MSTEVATATASTATSHPYTCNTCRIGYRATDLQKAHMRSDWHRYNLKRRVAGLPPITSETFSEKVLQAHAASNAETEKAYFEKFCNDCQKNYSSENSYNNHLLSTKHKQNYNSRLRAAAAAPAAKPDTLEESTAASSTFSLGEPIKTVTPVHDDEDDEKTVDKVAEAISKTAISEAPKEDTEMTQEPQASPLHTCLFCNFVSSDIDTNVLHMERTHGTIIPERPYLVDLPGLITHLYKRIKEDMACLVCLKVKSNAFAVQTHMRDTSHCMIPFTTEEEQLDIGDFYDFRSTYSDDEGDEDEMDLEEEAGAKLGAARSVKVTGENGEEIIGDDGWETDSSMSSTDSDEIGAVKADNNLSRLNKHSHHSHDDPRAHRRADGYHSHAHKHPRAAFYDEFELHLPSGRSVGHRQHQRYYRQNLEQYPTPAERAQLKLLEDANANSEQESRGRDPRSRAVTTRNQMGITGIDSSERAALQKETNKHQWQQQKAIAKKDYVVGVKMNKQKNYFYRYVTGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKB3</accession>
    <name>A0ABR3ZKB3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000652</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000008">
        <property type="protein sequence ID" value="KAL1901163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="148"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="307" mass="34971" checksum="805F8F8734931EAD" modified="2025-10-08" version="1">MLLTTTTAKQSLDFFSAKNIVSKMPSFFRNGLSIASNRKANRGATSSYVSSSSSSVASESISCKTTLVPRNRESLRVLSRKEYKEVALALSHAFANDELSRYMVDAPDMKNPSEEALWKLHVDMMTYISSYYFFTGQVVSIGPDYESIAMWVRPGEHEDGWWTVMRSGLWKLKFQLSREGKRRYYKEIVPSLDRLKKSIMGERDNDCYYLIYLGTKPSGRRKGYASRLLRDMIQQADREGKPMYLESSSPSNTQYYRKFGFECKEDIWFGEDRSVLLTAMVREPQNNAISSSHSGSDTASVSTNDST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKT0</accession>
    <name>A0ABR3ZKT0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RNA polymerase II-associated protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_000723</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007133">
        <property type="entry name" value="RNA_pol_II-assoc_Paf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23188">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23188:SF12">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03985">
        <property type="entry name" value="Paf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="424"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="429"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="451"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1900847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="474" mass="53511" checksum="C599847DAAFB0786" modified="2025-10-08" version="1">MSSSKPSSSSNGSRVVHQDYIARVRYSNTLPPPSLPPKLLEIPNTGLSSGQYTGPGFTSRMVREQQPNIEADAELGMPLDLVGMPGVFDGDESSIQAPATTPAIHPRDRPLLRPINSLGAPKPADVAVSFLRRTEYISGTTSKRTFIDNKAGPKRIEKRRTPVEDDDSPAGIRRKIDKSFEFAEAYRKNPSSVKHPENRNLKLVDAFPILPDLDAFPDSGAYVTIKFLTNPVPPSTHYDERLINGLLKPVETTPSEEAAYHQALELHERDPLNYSKPPPMMNYDFFLTHSATDTKRFRAKFDVNNPENDDDALYSHKSDNGPCFRFERVRGYETAKEIELNHTTKYSEELLVAFTDGKDSESQKAMWYYPIMQRSSIRPQRQRRLDIRRGFTQDDDQQDLDALDVRIEEPPEDMREAMLAFKENPCGEEVGEEVGDVDGDAEVDVEAEAEYQDKGMTDEQRGTQEEHNDEVDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKY4</accession>
    <name>A0ABR3ZKY4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Twinfilin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">TWF1</name>
        <name evidence="9" type="ORF">Cpir12675_000682</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Interacts with G-actin; ADP-actin form.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11285">
        <property type="entry name" value="ADF_Twf-N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028458">
        <property type="entry name" value="Twinfilin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13759">
        <property type="entry name" value="TWINFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13759:SF1">
        <property type="entry name" value="TWINFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ADF-H" evidence="8">
        <location>
            <begin position="3"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="ADF-H" evidence="8">
        <location>
            <begin position="174"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="332" mass="36750" checksum="C14201239AB0E033" modified="2025-10-08" version="1">MQSGISASQELFSQFKELQSSDSYFGLLVTITNEKLEPIRLLERTSPDFTANLSTLEPHLSDNEALYVILKRYDSNPVFFAVTFVPDLAKVRQKTLFASTRLTLVRELGSEHFRDTLLANAKEELSAAGFAKQDAHAAIEAPLTEEEQSLQAVKRAEQEISRGTGRQEIHLGKSLDMPFNDEALEALNQLGSGSLDMVSLKINSATETVELDSAPASSPSSIDEVVKSISTTEPRFTFYRFHHTHDGTQQRPLLFFYTCPATPGTRAIKARMLYPLMKRTVLEAAASGANITVDKKFEVDEPTEITEATVLSDLHPKAAARTGFSRPKRPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM27</accession>
    <name>A0ABR3ZM27_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DEAD-box type RNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SEN1</name>
        <name evidence="8" type="ORF">Cpir12675_000282</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18042">
        <property type="entry name" value="DEXXQc_SETX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024481">
        <property type="entry name" value="Helicase_Sen1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056474">
        <property type="entry name" value="SEN1_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF495">
        <property type="entry name" value="HELICASE SENATAXIN ISOFORM X1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23576">
        <property type="entry name" value="SEN1_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12726">
        <property type="entry name" value="SEN1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="1 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase Sen1 N-terminal" evidence="4">
        <location>
            <begin position="90"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase SEN1 beta-barrel" evidence="7">
        <location>
            <begin position="1212"/>
            <end position="1314"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="5">
        <location>
            <begin position="1363"/>
            <end position="1667"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="6">
        <location>
            <begin position="1674"/>
            <end position="1870"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1076"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1412"/>
            <end position="1436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1986"/>
            <end position="2046"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="2060"/>
            <end position="2179"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1026"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1082"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1113"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1412"/>
            <end position="1429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1990"/>
            <end position="2002"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="2104"/>
            <end position="2115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="2141"/>
            <end position="2151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF23576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="2179" mass="241743" checksum="12FD83D519D6D38B" modified="2025-10-08" version="1">MDQSSLDETLNHWRLELENITPELHILCPMTHADDPENYAETEPTSGITAEDKKKRLEDAKERINITMWNSLLFGVERKKVEQWLETYASRLQNALSSCDACIKNWHRCRKSFLIGLSENYSHEVVTALERLIINFDFDRLDSRLKWSRDRIEAVEQPGKPFKLQILGADVSAVLLTVYESMCCVDYLRMLDKRKNFEFVFQRLSGGKKPLRLGANTLLPAMTEFLFDPDPVCLRFANAAWASLDPGSMSADQFDWAVGEFLVRASVSVGALDITQPQNLEQISRFWSGALAIFNVMTPDVIVHRYRALEERPNLYDLLFIHMQCQSEEILLLVLDAFSVLISKAPAAFWDALSHPRPFSVVEPAFAAPMFKTLLNKTLELGLSISGLPKPIAWISIWGQSLSRDQRGDACSSLLHLLFENFVKDPSLGESGKAACVKAGLDTLADLLDSYLNPTNEKDALAMQSLASSNNLVFANNALNMTLKYSEIIVMAAENKRSLLGEKEAAVSVIEKALLLDARAFAAEAKQLHMGGPVQQMVTRNSAGLWDAYLELIYPGNLTLATTMLRPLLSILPVEQFRHERKATKPMLPAKVAFNKRFGESAAVIGRLLQRLCDFDECDKQVLSQDSHLRILLAMMLHGEEEISLAAIELVKTITGQGSRSEAVLKLITERPAPVIRAFTVAINTTAKPYRNKDGEEVSPPWGSMKHILNTAKDIINGLFDPTIGVLRVKSLDRSEIDTVHAWWLCQWHWVQVCFDATQNWSYFVEIKIMTDFCREVIELAESLSSNDGVLSASSKDNMLKAAVASGATIDEEGFASKAMIRTLEPCRRFLMGLVRMIRLKDEYLVEITTKIICKLLNRLSEYKLPIPDDVQMYLQRACKPRPTDGRFEIGTKLSSQQKAELLRAASIDDDDDDVTIVSVIPSARAGSLSGPPGTGRTNAKGQVQAKLDLMSWGKLGAGASSSKPLTGRTNADDVADLSSTLESSKSTLDAMAAKEAKLKSKSTSVTMQSIQAIRAKAAEQSAVVQAKHADKVKAKQNALKEARQRERDEMARKRAEFIARDRAARGIVIKEKEKSEIMVDSSDEEEDDDDDDDGEASSLIRSSKAGMDALNEAERRREKALMGKIRGPVKKIKIQRTAKDNRARLTPPMDTLHSEILSWDIFHDGDAPPNGLELMHVATTFAQPVLYKNTFLPLLIYEAWRSFVTDKNECTAKVFGIKIITRMTVDRFLEITTTIPATNRSENRERVVSEGDIVLISKDEDPLNNAAAAHCLARIWRVTFKKSVLEVTWRLNQRENPLARDLTPGAMLNAVRITNMTTIEREYAALEALQYYDLMDEVLKGEPSPILNYSDEQIRRYMDNWKLNAGQAKAVLGAKDNDGFTLIQGPPGTGKTKTIVAMVGCLLAGSLASASTTSSSSSTGITSIKAIGQQPPATRKDQQTVMKKLLVCAPSNAAVDELVLRLKQGVKTAGGQHHKINVIRLGRSDAINAAVRDVTLDVMVQTRLEGDQTKNQALAERDKMHVEAGQIKEELALLRPKLEAARDSGNRNEYSAMQRKFDELKMRQTRIGAKMDADKDSGNTVAREVEMRKRMIQQEILDGAHILCATLSGSGHDMFRNLSNIEFETVIIDEAAQCVELSALIPLKYGASKCILVGDPKQLPPTVLSQSAQRYGYDQSLFVRMQKAHPEDIYLLDTQYRMHPHISAFPSREFYDSKLIDGPNMSGLRSMPWHDSILFSPYRFFDVKGVQGRGAKGRSLVNLKEIEVSLQLYRRLKADYPAVDLTRRIGIITPYKAQLAELRFRFAREFGDAINDSIEFNTTDAFQGRECDIIIFSCVRASPTGGIGFMTDIRRMNVGLTRAKSSLWILGDSNALAQGEYWKKLIEDARQRLLLTDGDIQDILRRPTQKGALPVEASGVHIKHEASALAEAEFPLKRELIPKETTPEDRIIKSDVAIPVGHGQPPRGPRLSTGSFAYTIDERGVPIAEAHPTQGSGRPVIQTSVPGLPQGKKRPGEDQVLPAAKRGPSPAPPNAPRGPRNPRSTGNIGSGLRAQMIQRQNQNSHNNHNNHNNRHHIPNRPPSASPVDPSAMETMGLVPPQRPPALTPSQPSRNSSGYPDSDSPIAGAQKQSSLTPIGAPTGPASMTGNSNANGRNPAVRPPMPRKRTPADPFIKKRPPPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM51</accession>
    <name>A0ABR3ZM51_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018853">
        <property type="entry name" value="DUF2457"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36812:SF9">
        <property type="entry name" value="MYB-LIKE PROTEIN X ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36812">
        <property type="entry name" value="NEUROFILAMENT TRIPLET M PROTEIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10446">
        <property type="entry name" value="DUF2457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="431"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="547"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="658"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="447"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="547"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="561"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="668"/>
            <end position="679"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="764" mass="84454" checksum="FC397EA6A017DE6E" modified="2025-10-08" version="1">MSEHLSHTTMTGASAWASQASSLSVLEEEASADVDEPPDNRKPKSSLFSKEAIRRPSFLQARSLLTLALKNDDDDDEHDDQEDDAEAHDDNDDNRNDVYDNNCPPIECQRSLSMSSAADLTSDTGLTSPSRANTPSPSPPEMVHFVPNRRVSIAFSEIGTKKRISFACGAPEKPRERRISFASTNAAKKPTIAVEEPAPRRPCIKFACGDTKASAIKVSRNRCVSPPPPIPVSSSVQATTGLPVVIPSGDPASTSTIHASLSRTPIKSPPNAILSQIAPLPSGPKKFQVDESTVKTKKPQYFHTFAGNVDDQDDWMESKTPIGKKITINDTLVKENVIRRLAKEVEEEEDAENEENDNDEENDEDEEDEDEDEDEEDEDDEMDDDNDDIDEAGISDGEYDSDGYHTDEETGFASSDDEDDDLHLWVLTNSTPIPCSVPIKNAHKSSSKATSSSSSYVSRSMSKKARRPSIRPGTPELPDSTDFVCGTFDEDRPMESAYLSCIEQRRLKKLCPIPQDIDPSFPASDPEDETESIFEALKSSSGEHMLLHGDLDDLNHDQDRRGRRKSKSKPLSPKRFHSPAPKGQHARSPAPRRMFSPPPKARRAADRQSPKMRARSPAPFAHCRVPISPLISPTHGRLLAMPLPRINEMTQTKSLPRAGVTFAPPQGHKYRKGRPANKKHVRGAIDIIKGLERKRQKRKEKMYQEYCNRARKGQKESCKMLPGQGAEKMKVIGLLQSGKNLSQVKAQLQQPPAPQAGGNYMMSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMF0</accession>
    <name>A0ABR3ZMF0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Monopolin complex subunit Csm1/Pcs1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_000334</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23787">
        <property type="entry name" value="RWD_CSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040349">
        <property type="entry name" value="Csm1/Pcs1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020981">
        <property type="entry name" value="Csm1/Pcs1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038608">
        <property type="entry name" value="Csm1/Pcs1_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28006">
        <property type="entry name" value="MONOPOLIN COMPLEX SUBUNIT CSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28006:SF1">
        <property type="entry name" value="MONOPOLIN COMPLEX SUBUNIT CSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12539">
        <property type="entry name" value="Csm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Monopolin complex subunit Csm1/Pcs1 C-terminal" evidence="3">
        <location>
            <begin position="419"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="152"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="292"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="162"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="198"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="523" mass="56769" checksum="86474E0CD3032F3F" modified="2025-10-08" version="1">MPPARKPKAKAKAAPPATSTLGGLVEDSELEDDLSNMSVTRPAPKRKTRTATTTATKTNKALEKQPEPESPTEPAPKKRGRPPSMTKGGNKVQKSAAKPPRAMSSRTKQALADEATLVSEMSTMSAQGTTGRGKAVATQYAIIEDEYEDMIDMSDTQPIAPKRGRQTKKKVVMMDPSADTPPAKKPRGRAANKATIEPEPETELEESQMDEPTEAMEGKDEDVTQATAIPPSPPQPPVKAASASSLRGKKRPAPVDADSGSGEVTLRRKLGEMNTKFESLEAKYSTLRDIGIKEAERNYDKLKKQGEERAQTSTQLIAQLKEQVKAQTELAHEGESLRIELEQSEATVDVLRAKVTALEQSLTDSRAENKNLVTKLAASRSDISVGSGTLGKGASSSGILGGNGARTMAASNEMVLAAQMKEDLYGDLTGLIIRGIKRSDSEDVFDCLQTGRNGTLHFKLAIEQEEGGNGEYEEAQFTYRPQLDENRDGDLIELLPEYLTEEITFPRPHSAKFYTRVSRALME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMI3</accession>
    <name>A0ABR3ZMI3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2 NT-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000843</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039931">
        <property type="entry name" value="EEIG1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019448">
        <property type="entry name" value="NT-C2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21456:SF1">
        <property type="entry name" value="C2 NT-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21456">
        <property type="entry name" value="FAMILY WITH SEQUENCE SIMILARITY 102"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10358">
        <property type="entry name" value="NT-C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51840">
        <property type="entry name" value="C2_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2 NT-type" evidence="2">
        <location>
            <begin position="7"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="287"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="407"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="466" mass="51918" checksum="066839304B6E0278" modified="2025-10-08" version="1">MKKLFRTHEANVRQPRFELHLKIYDLNNVPLVAGWSLIKWHIVHSIHAEHRGATERRAIANHRVHYSYSKLVGNVRIPIDKSLRLSECWLELEVLQEYSSGGLRDEKVPLGKVRVNLGEFVEESMNMDIQLLSRRRPAAMASSAAGSSLSSQYDVQDGIIRRYLLQDSKINSTLKIGVLMVQVDGDRNYSAPPLKTAPVFGGLAGVFVGEAPDQEDGNKVPMIASNKARDVAEVDLYRSMLIASWNCPLDELRADEAIEDIFHQGDSKHSPYSPHVHSHGHTHRHTPSSLPTLTASSSAKRFAHSHYSSTYGRDESGSGDENYASISHNYGHGHGHRSGGKSHRDHRHHRTSSGLSETSAATVTRSGYSGNRAPTQDRITHRPLAGTPSVHRRNISRSSNEYLTLGARSRSSSFTSLASMDGSGDDYSRDTDAHDIELRHISGREVREHEIRENMVAWTVPTQQTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMW5</accession>
    <name>A0ABR3ZMW5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000268</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17080">
        <property type="entry name" value="Ubl_SLD2_Esc2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022617">
        <property type="entry name" value="Rad60/SUMO-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11976">
        <property type="entry name" value="Rad60-SLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="411"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="179"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="209"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="485" mass="53373" checksum="ABF7DE6EA9EF27A4" modified="2025-10-08" version="1">MESGASSTSKKLPFKRRTTRKVVEPSGGEEDSLNLFKRSTQMIPKFVAEADERVKRAEMLKEKHKRERDAIEKRAREDDFSDDDGALEEIPKKRQTTESKSPSSSFRSPDSSHATSSSSRLDSQNPAQSQKEIAPPSSLSNISEVVELDSDSDSNPKPDNADDDDSPLAVIDDVEDDVQPVPVNQVSDPELQKYIEEARKARLRREQLEQQQQERTPTSGNSTSNLSTTTPSRPIRGQSITTVIISHIPGTSEFPGFHIPVEKPLEELKQSWIEQQSLRGTPVPDEHDVVLTWRGNEIYSTTTLQSLNIGVGTGSGGTLRVHLRGDSKNNSGFSADGRKAIFEAWTHALLQQDREHKARMALHDSDDDSGAGADDREGLGAYSSSAAGNYTSAATATSQPVDEEDISQTKIRLTLQAKDGQTSKLSATPETQISMLVQAFMRKNQVPAGMRVEIRFDGLALDSDSTLEDAEVEDRDTMEVHFVPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN66</accession>
    <name>A0ABR3ZN66_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Reverse transcriptase Ty1/copia-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000037</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013103">
        <property type="entry name" value="RVT_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07727">
        <property type="entry name" value="RVT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase Ty1/copia-type" evidence="2">
        <location>
            <begin position="31"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="141" mass="15692" checksum="E4ECA3058BA583D6" modified="2025-10-08" version="1">MSPSPATTRPGAQDSESATHNEDLTVNGTPIIANRWVFTRKSDKSFKARLVAKGFSEPFVTAQMAYADTAHIVSIRALVAYAAVKKYQVRTADITAAYLQAELDTRNGHKAEQTHIWFENRRKTLATTSEGHSHIHRLRSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN97</accession>
    <name>A0ABR3ZN97_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000414</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39472">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39472:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="258"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="75"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="258"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="313" mass="35785" checksum="B13EA8C39B76C115" modified="2025-10-08" version="1">MNNANGNNPASSAGAVMPAGYQAELNYIWSLVEELSKQLADNRKKTDEIVSNIGKVRQRARDQNIPTHDLIAAAADGLNAQSANYEEQISILEEALDKTKHSRDSNMRLLQDFRQVTLNMLQQFHSYKSQHVADVCSWHLSYRAQLSEAREENCRLREQIWNMQAHAGSAHDLMRQLRKLLVEDEARHNHSVDDVAHRQEVRFWKRMALPQIPDDDPYWSDDDDLVDPHEKLRLQLVQAELAAKAAEAAEFEAAMIREREKDRQREEEHRRGREMDRGRLENDDAEDDDVMSAPPPLAPSPMMGFGTWTGPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNF8</accession>
    <name>A0ABR3ZNF8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="8">1.2.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_000091</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = (2R)-3-phospho-glyceroyl phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10300"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="1.2.1.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 1/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.12" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18126">
        <property type="entry name" value="GAPDH_I_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05214">
        <property type="entry name" value="GAPDH_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10836">
        <property type="entry name" value="GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10836:SF76">
        <property type="entry name" value="GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 8" id="KW-0520">NAD</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding" evidence="9">
        <location>
            <begin position="3"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1902191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="337" mass="35655" checksum="C282702FF03CA58C" modified="2025-10-08" version="1">MTVKVGINGFGRIGRIVFRNSVGHSDVEVVAVNDPFIDPTYAAYMLKYDSTHGVFNGTIEAVSDGLVVNGKKVVFFQERDPANIKWASAGAEYIVESTGVFTTVDKASAHLKGGAKRVVISAPSADAPMYVMGVNETTYDGSSAVISNASCTTNCLAPLAKVINDNFGIVEGLMTTVHSYTATQKTVDGPSAKDWRGGRTAAQNIIPSSTGAAKAVGKVIPALNGKLTGMSMRVPTANVSVVDLTVRLEKGASYDQIKACIKAASEGPLKGVLGYTEDDIVSSDMNGNNNSSIFDAKAGISLNDNFVKLVSWYDNEWGYSRRVLDLLAYVAKVDGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP33</accession>
    <name>A0ABR3ZP33_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Serine threonine protein kinase CMGC group</fullName>
            <ecNumber evidence="9">2.7.12.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">LKH1</name>
        <name evidence="9" type="ORF">Cpir12675_000497</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.12.1" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004712">
        <property type="term" value="F:protein serine/threonine/tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd14134">
        <property type="entry name" value="PKc_CLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051175">
        <property type="entry name" value="CLK_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE DOA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646:SF11">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE DOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="649"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="199"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="342"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="394"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="470"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1015"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="355"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="409"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="422"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1015"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="678"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1037" mass="113645" checksum="00F7132867E59C2A" modified="2025-10-08" version="1">MSTPTTATATTLPHYRPRHYPQYSHTYNEQQQDQQKQQEHYHHQQNPPSSRNPSASTGANSAASGSVITAPVSASTVTATASGLSVAATAAVSAASDSATASAITSITSITTPSVSAGFSAVAARSSVPSPLPTATAAAVPILPASTSTPSSTTFTSSSFENTRSTSIVTSGSAAAILSAAPAIPATPTTTVSATITSSNLPCLNPNNGSTSTNASSTSSNNNNSAIPSSAASSISLSSRLLPPYRSLPKPYLNGYHSHSINNIRSHDYENYDYDYSSHNHHHSTLLQSPVHAPAHMALSQKNYNHNQNHTHAHSHNSAYNAYTDLHISHQSQIQIPVLSPAQQHQKPYSPLGNSASGSSTYTAPSAAASSATAAGEPSELSVTLPPLSSLPSVPALSGPNHHRLGHISTATASPPNLSCLQSQTMATTSQSSQSQSQSQLTPARKRRRSREPDWTDFYKNGLPKEIIVIDDDSPENGPIDPVTLNTSNTVSMPLPHHPQTQNDQQATKRRKRDDEEAVYDALYHNTKYSASHTTTPRLNATPMSHSDRASALLNSSATSLSAHDLEIAQSGQKRKRATRQQIAHEARLKEAEIHLDSLVPYVPPPYPPRKAPDVHIRVVHDHYHRNHKVDDDDGHYIVVPEGELTERYQIVKLLGQGTFGKVVQAKDRRRNKLVAIKIIRSVQKYRDASKIELRVLATLKANDEENRNRCIHLRDCFDFRNHICIVMDLLGQSVFDFLKSNSFVPFPNSQIQSFARQLFTSVAFLHDLNLIHTDLKPENILLCDNTYQTFTYNRKIPSASCNTPRQANQRRVLLDTEIRLIDFGSATFQDEYHSSVVSTRHYRAPEIILGLGWSYPCDIWSIGCILVEFFTGDALFQTHDNLEHLAMMEAVVGNRIDSSLVQAVNRAASRSAAGNPASKFFKRLRLDFPTPETSRTSRRFVKAMKTLEDIIPANNAFLKSFLNLLRQIFVYDPAKRITAKAALQHPWFRELPNPDDGTEALKIRAERMRIEQLSRSTSASVSHSHMDNRTLAPIRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRH3</accession>
    <name>A0ABR3ZRH3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoglycerate mutase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_000196</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1902089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="196" mass="21982" checksum="59D4879B41D9CB54" modified="2025-10-08" version="1">MRRTIQTALIALDFLRQKGVSFVADADWQAVRNSYADLILETTAKPCDTGSDIATLKAEFPAINFADVDPVYPDKTSPAGQQYAWGRSALLARGARARNSLKKRPEKWVIVVSHSGFLRQAVCGWWYSNADYRIFDFVGEASAETRTKQEADAEVEKTGLRLRDETKQGGMGWSWYKRVQLGEGMKPDVVEATEQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YCZ5</accession>
    <name>A0ABR3YCZ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">DNA polymerase epsilon catalytic subunit</fullName>
            <ecNumber evidence="18">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">POL2</name>
        <name evidence="21" type="ORF">Cpir12675_006938</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">DNA polymerase II participates in chromosomal DNA replication.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="18">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 18">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 18">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="18"/>
    <dbReference type="EMBL" id="JAWDJO010000439">
        <property type="protein sequence ID" value="KAL1886008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05779">
        <property type="entry name" value="DNA_polB_epsilon_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05535">
        <property type="entry name" value="POLBc_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.342.10">
        <property type="entry name" value="DNA Polymerase, chain B, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013697">
        <property type="entry name" value="DNA_pol_e_suA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029703">
        <property type="entry name" value="POL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055191">
        <property type="entry name" value="POL2_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054475">
        <property type="entry name" value="Znf-DPOE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10670">
        <property type="entry name" value="DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10670:SF0">
        <property type="entry name" value="DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08490">
        <property type="entry name" value="DUF1744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22634">
        <property type="entry name" value="POL2_thumb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22912">
        <property type="entry name" value="zf-DPOE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23250">
        <property type="entry name" value="zf_DPOE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01159">
        <property type="entry name" value="DUF1744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 18" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 18" id="KW-0235">DNA replication</keyword>
    <keyword evidence="14 18" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11 18" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="12 18" id="KW-0408">Iron</keyword>
    <keyword evidence="13 18" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 18 21" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16 18" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 18 21" id="KW-0808">Transferase</keyword>
    <keyword evidence="10 18" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 18" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNA polymerase epsilon catalytic subunit A C-terminal" evidence="20">
        <location>
            <begin position="1514"/>
            <end position="1907"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1226"/>
            <end position="1253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="19">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="1238"/>
            <end position="1253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU365029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="SMART" id="SM01159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAL1886008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="2225" mass="255013" checksum="05321DB990AD4158" modified="2025-10-08" version="1">MPNTSLRKPQKGVTRRGKTAYHGSQATRTFTSTPGRFEATSTDEKWERTRMAHQIDEKMGFERIESGKRKEGWLVNIQSTSIPDDRNVNGRAALDCYFIEDGNESTFKATVEYEPYMLIAVRKGRESEVEEWVKRIDGGGVVKAVAKIEKEDLTMPNHLLGYRRTFLKLTFLNIFDLMSARREIMPIAERNRKNMNAMDAYADVVRTTGELDLYDDSLERDERENVNVADASDYIVDIREYDVPYHVRVMIDLDFSAGVTTLKINEERLAMADPVVMAFDIETCKSPLKFPDSSVDQIMMISYMIDGQGFLITNREIVSEDIADFDYTPKPEYPGVFIIFNEPNERALIERFFEHIKVSRPTVIATYNGDFFDWPYVEARAAFNGIDMYQEIGWKRDSEDQFKCNYGVHMDCFHWVNRDSYLPQGSRGLKAVTVAKLSYDPDELDPELMTPYASERPQTLAEYSVSDAVATYYLYMKYVQPFIFSLCTILPLGGDDTLRKGTGTLCEMLLMVQAYQKEIILPNKHVSAKESFWEGHLLESETYVGGHVESIEAGVFRADIPVNFAVQPAAIDELLQDLDAALKFSITVEEKKSMDDITNYNEVRSQIVERLTQLRDTPNRNENPLIYHLDVASMYPNIMTTNRLQPDSMIQESDCAACDFNRPGKTCDRRMPWAWRGEYIPAKRDEYNMIRNTLEGEKFPPRRPGMPMRSFQELPLDEQAALVRKRLQLYSQKIYHKIHESKTLVREAIICQRENPFYINTVRDFRDRRYDYKGKAKVWKGNAEALKSSGAPTSEVDAAKKMIVLFDSLQLAHKVILNSFYGYVMRKGSRWHSMEMAGVTCLTGATIIQLAKDLVDRLGRPLELDTDGIWCMLPATFPENFSFKLKNGKKVAISYPCVMLNHLVHAKFTNHQYQTLVDPAAFKYETHSDNSIFFEVDGPYKAMVIPTSKEEDKNLKKRYAVFNHDGSLAELKGFEVKRRGELKLIKIFQQQIFKFFLEGATLAECYGAVSKVANRWLDVLHNKGSTLSDDELMDLISENRSMSKTLEEYGNQKSTSITTAKRLADFLGEGMVKDKGLNCKFIISYIPRNAPVTERAVPVAIFSAPEETKRLYLRKWLKEDPASADPRDLLDWNYYLERLGSVIQKLITIPAALQKVRNPVPRVTHPDWLQRRINQKDDKMKQKKLSDMFTVKSSESRDNPGNRLVDVEDYGNQLAKAKTIGAAFASSQVSSSPMPKRKAPERDETPILEDLPKKMPDPSEDYIAFLMYQKRKWKMQKEARGRRRQLFGDRRMNNHNSSIQQTMMRQAHSTFTNTWQILHLKATDSPGIVLAYVLIDAKIHPVKINVPRQLYVNFKTKSIPELKLKDCSIKPANVTLPSGHLPVNLVQLTMSEESYVTEMQKWFPLLNDRTVEGVYEQKLPLNMRALLQLGNSCTIDQFQEAVLGKGLERGFDLSGLKQPEKKRNYLESVPLAFIYISQITTGDKQIYGIFSSRAEQAHVVILQRSRETMQDIPNISRIYEEKLREHVAEVTASNGSIQDFFQFQEKLTFKVTQVTTQRKANLEIGDVVKKMHREELRAQVLVIQSSQRESLIHNIPILGEFPTLPMKYDVYDGSLPPLGWQPVAVRRLVRHYLRLAGEITHFMALARYADIPLCNLEKEDPRFLIDVSYARRLQANNVALWWSADARPDHGGYEKDNIAGPLDMMAMPQVNHPGTYLTVCIEMEVRNLAINTILTSSLINALEGSEGEMFNADPSTDKDGTSILYSHNSFSGAGIRVLRGMVKSWWSEACRGSPMADLMVNHLLRWVEDPDSYLYDSTLHRYVQLICRKAFQQLMGDFRRVGCQVIFANSSRLILQTTKQDVETAYAFGQYITKSIKTQPLFHFIDLDIKEYWDYLVWYDEYNYGGVGCEEIAEHEGTQELNTVMHWQMQTFLPPRLQSVFGDWVVEFIRIMHNLKRPNAAVSGTPRMTQIPVHNLTADPESTNLTNIISGPVFEKPLKKEIASLITRQKREMMHAELAADYAFPNLPGSHISGLDIHKAILELVKAIMQILSLDKNIIMEARLLRKELLQMFDISDFSTAGAFRNPSESLILRDISCGNCAMPREFDFCRDEDLLPADLSQGAGENTWRCTGCGFEFSRMRIEERLIAAVESYVIEWTTQDQKCKVCGAVKLGEFMDHCTCSGEWKNMLSRDDIVNRLKVYKNVAEFYDMRMLYSVVGEILSAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFW3</accession>
    <name>A0ABR3YFW3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">CCR4-NOT core subunit cdc39</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">CDC39</name>
        <name evidence="12" type="ORF">Cpir12675_006739</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000364">
        <property type="protein sequence ID" value="KAL1887024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20710">
        <property type="entry name" value="NOT1_connector"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.840">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 1 TTP binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007196">
        <property type="entry name" value="CCR4-Not_Not1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032191">
        <property type="entry name" value="CNOT1_CAF1_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024557">
        <property type="entry name" value="CNOT1_dom_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032194">
        <property type="entry name" value="CNOT1_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032193">
        <property type="entry name" value="CNOT1_TTP_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038535">
        <property type="entry name" value="CNOT1_TTP_bind_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040398">
        <property type="entry name" value="Not1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13162">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13162:SF8">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16415">
        <property type="entry name" value="CNOT1_CAF1_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16418">
        <property type="entry name" value="CNOT1_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16417">
        <property type="entry name" value="CNOT1_TTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12842">
        <property type="entry name" value="DUF3819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04054">
        <property type="entry name" value="Not1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 HEAT repeat" evidence="11">
        <location>
            <begin position="524"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 TTP binding" evidence="10">
        <location>
            <begin position="699"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 CAF1-binding" evidence="9">
        <location>
            <begin position="918"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1" evidence="8">
        <location>
            <begin position="1205"/>
            <end position="1341"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-Not complex component Not1 C-terminal" evidence="7">
        <location>
            <begin position="1816"/>
            <end position="2182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1393"/>
            <end position="1446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="10"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1426"/>
            <end position="1446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1887024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="2185" mass="244293" checksum="E3D20E9C3A367C4D" modified="2025-10-08" version="1">MVPQPRGGSFSPTPSAHSLQTGTSHSPRPSISQAGIFSAGASPNINSPTGNNSLTKIVVAQVYLLLGALKDDRDRSKWASQVEQLRKLVDENGMEVFSKYFARLIAGNASQIFPGMNRQTSSTVLGNYQLIADEMARIAILPDQARKIAEAIETGSEDIFRDFDLSTFMDHFKLDPLEKTILALAFKVGTRSDLKTKVDAILSANFTTFADILSRSDGPHSQNLTPDFFSLILDRFMQYPPPNFNAISKGDLAQKALKRYVDSPSGQAPPSEVLAALDLGRLLTDAPSNALALYMQKSGVDFTRDEASCTRSLRNRPQNLQLNELQVAIALLYATISQSPEFKPAVLIASLRKVVTPAFNWSEVPCYFDQKTTRVSSGQFLILYRALLPIAQDSSIEPPLNLQKLWGDGWENTEANLSFVCAFANLSPETLDATTIPHLVPTITLDTYSESSDSIKNRAAFAVRHPLVSASALSAVFHAALNSLHASQSMEAKRLFQEVVIPNLDLFVVSAFGVPKPWPAMAVETLGSLFDNFFYKRSQHWDFVLESLWKKDREWVVRRLIDAHASSPGDLTLIFEHAVNHNWLDELVHIENGFGIDLAAFAHSKGRLDLDLWAQRHLDNSAEMANNLMQFLVIKANFEGAQSAQAASGSTSLQVKTVHALFNIIDEFLAGNPTPTLIRTQRACITVYPRLINYSEGFDDIIDINGEKGNELPPEANNRMEIHYKKMYGAEVEVREIVDTLRAYKTSQSPLDQDVFACMIHGLFDEFAHYKDYPVEALATTAVLFGGIISHKLISGLPLKIGLHMILEAVRDYPSDKAMFKFGFQALQTISPRFREWPAFAHQLASISNLRSSENWPKLRDALLFLEDNPHLGHETDAHVGFTENGECSVLFNSSPSRQLSQPFSSIHVDPTPAGVVFEEPDPKQQDKIQFLLNNVTREKLGGTSSEIHEILEHKYLQWFAGHLVEERAKMQPNYHSLYLDLVKILDRQSLWSEVLRETYYSVSLLLNSESTKINATERGHLKNLAGWLGLLTLARDKPVKHKNIAFKQLLLEAHHTDRLATVIPFVCKVLIQGASSNVFKPPNPWLMDIIHLLIAIYHEASIKLNLKFEIEVLCKGLNLDHRSIKPPDGILHRPSAPERPIDRILPDRSDGFDSIPINGVGVNGVGVGVPIGLTTQPVILDLPDISTQLQIPPTNEMVITPSRLHELVRTALTRSIADIIQPVVDRSVTIAAISTQQMILKDFSIEPDESRLRTSAINMVKSTAGSLALVTCKDPLRATFTNYMRQLSAESSHNLPEGTLLMCVNSNVDLGCSVIEKQAEDRAVPEIEEILEPELEARRLRRAQKPMEPFVGRPLDRWASAIPDPYRLVDGMRGLTPEQMAIYEDFARHPRANASVQTSHPHPGPEGDRSLVPETLPEQFGGSIASASGQPEALNPSQSGNSQSYLATATSTTRQTDLPLLANRFMKLLHELKQRILAAADLSGEHFDNLPRPHPIIDVYDALLQTIISVVHSSEELSLFSAREILAMLFTSTDSTLGVETYLSVLDSLRKMSSPCVNKKIQEIFRQQPPEYIIHRPMLPALLSTDLVDWEVIDTTVSQALQSRQELSLQLLEHILDLTLLSERPVILYANLIRTLEAAWSWIVENPENPSCQHLKLKLQHAFMSLPQQSGPDSIELRKDQMEYIFNEWVTICAHPQAMETLPVFLTQMQACKLLNSRDDLYTLLRVGIDLSVAHFDERSPGRSNNSLSTVDALAHLIITCSGPGSPVADIENSRPAFIRSCIAVIHLAMYKNHETRGEHFSQRVFFRLLSLVLLHINEMHELMSPADTEALMLSIGRTILDLGPQFLPCFSYGWIRLIQHRSLLSVLLQIGSSECLDVVTDILCQLLIYLGEQLKALEVQEVSKDIYRATLKLLLVLQHDFPEYLAAYHNKLCRFVPFHCAQLLAVILAASPNITDTNATAHLGVRFESLQELRDCPKVAGNVEETLSRLGLLEVLERTLENSPLEDAVAHIAHAIRESDHKETAFGFVPVHANLSIIESVVIHIANFAIQRARMDGNKIFRPEEPDVKFLSMLIREVDASTRYFIIACIANQLRYPNSHTAYFSQLVLSIFGSDMADPDATEVRQQITRILLERLIPFWNFPWGILVTVIELLKNQAYMFFELPFIKSYPEVADRYAAVLRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG07</accession>
    <name>A0ABR3YG07_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Phenol 2-monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_006618</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PheA/TfdB FAD monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000336">
        <property type="protein sequence ID" value="KAL1887258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02979">
        <property type="entry name" value="PHOX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012941">
        <property type="entry name" value="Phe_hydrox_C_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038220">
        <property type="entry name" value="PHOX_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF4">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07976">
        <property type="entry name" value="Phe_hydrox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="46"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Phenol hydroxylase-like C-terminal dimerisation" evidence="7">
        <location>
            <begin position="433"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="657"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1887258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="676" mass="75242" checksum="F5BE34FBE4AF5932" modified="2025-10-08" version="1">MAPGVGHPDTDMDVQSGTLPSNALSIAGAADTLSLLRSMPQPPILCQVCIVGAGPAGLMLASNLVRFGIKIEVIDDRHDQTTAGRADGLQPKSIETFRQMRLADPLLQRGVRVYDISFWRSTPEEPLHRLGREVHYPPIIDVLDAYILLVHQGVVEGLFIEDMRKRGAEVRRNTAFDSYSVPENKSGPLQVNCRANVNQERRTLLTQFLVGCDGAHSKVRKSIPDARAIGMSQDAIWGVLDGELITDFPDIWSKTVIFSQEHGSILIVPRERNMTRLYIELKSSPKADRREYGQEFIMRRAKQIMAPFEINWQYIEWFGRYQIGQRVATRFADQHLRAFLSGDASHTHSPKSAQGMNTSMHDSWNLAWKLNLAVRGLAKPVLLESYEDERRKIALDLVNFDYEHANQIAEGDAAALADNFKTNVRFISGIGAEYAESIINRYDNDTFAFCGDAKPGCLLPPAKVTRYLDSNPVDIQLDIPMMGQFRIYLLTWDVRQAALFLDDFCRSVASNDSLLSQLSAAASKSYAAQPRVPAPDLDVYQRPERYTVVSHLFTFSLITTMPKDDIEISDLPALLQDSKWSFYIDNVPDLDTRGIHCTNKWLGSLGPGEVAILNVRPDGYVGSIGRWDSSVDNTGHEAAKWLDHYYGGFLQVPPTTAKGANGNANSGNSSGKDVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGH5</accession>
    <name>A0ABR3YGH5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_006716</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000358">
        <property type="protein sequence ID" value="KAL1887070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1887070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="64" mass="7041" checksum="D422B8F4B6879CA3" modified="2025-10-08" version="1" fragment="single">KANGYQHGVLALTEYAGGVAARHMGNIYNIEKIRFYQRRAFIAQLAERDTSNVEVSGSNPLEGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGH8</accession>
    <name>A0ABR3YGH8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Peroxisomal ATPase PEX1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Peroxin-1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">PEX1</name>
        <name evidence="15" type="ORF">Cpir12675_006543</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000319">
        <property type="protein sequence ID" value="KAL1887438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19526">
        <property type="entry name" value="RecA-like_PEX1_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029067">
        <property type="entry name" value="CDC48_domain_2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015342">
        <property type="entry name" value="PEX1-N_C-lobe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF12">
        <property type="entry name" value="PEROXISOMAL ATPASE PEX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09262">
        <property type="entry name" value="PEX-1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="ADC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54585">
        <property type="entry name" value="Cdc48 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="542"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="894"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="237"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="723"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="743"/>
            <end position="752"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1887438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1301" mass="139807" checksum="CD7A11FB2DECA364" modified="2025-10-08" version="1">MFSGGLFESIRPRARNPRSTTAELSLVPLKSCLVNLPTVLESLLVSVNTPAQNAIVELNFRPSNASSSQPSRSVYLGWTGMPSKHKMPSLVGGRDSGYGGLRGQSRESEAHLVEIDSVLATTLGLHDGQKVLTTVHIDPPQAHTINIEPLTPEDWEIIELHATFLELNLLSQIRAVPNPFFKPASGQSTPENCLTVHLTPTSTANIVVTSIEPAPSAEHAFAKIAPDAEVIVAPKTRPKTSVRGADTRSVASTTKSKRSSATKRVREVPRPAIYLRGLDFAACDPYSFGNDHLLTHGNLDFTVWVDSNAIATGGMKGVNYVVVELLRPSTGPKKVKPEDAGNLKPENKLVARLKEWDDAATGQSVALSSPLCAALGSPGLVGGVVKIQAALPQITRPKHIKVFPFATRSKEGHGLKFGGESKSEKEESARRICQIYSNGNQPGHVFGGPVTDGMLLGIYPGLGDTTGWEGGILKIEDGSSDKDHHPCWLLGIDEKAPIEVQPPIPPPVVSKEIEHWDPTPAPEGVLAGVDSLFENLYTQLHHMSSTLLTGPMGAGKSELAKKLAQRIRSEELYYTIYFPCKTLINDETRLNTVKDSLVRIFTSASWGARLGGKALVVLDDLDKLCPVETELQVGNDNSRSRILSETVCAMVKQYCAPDSGVVLLATAGGKDTINKAILGGHMVRDTIEMKAPHKEARREILSSLILKDSSALPCNGKLFASDSPRNSTAVGPSNEDSSAAESTDADDDDWMETDNPKSSCSSRRRAKRSNAGESNGFIVDADLDFLEIAGLTDGYMPVDLSMLVSRARSEAMFRAISASSSYDEEEGSLYLTRSDFDKALQGFTPATLRNVPLQKSTTTFASIGGLAETRQVLLETLQYPTKYAPIFANCPLRLRSGLLLYGYPGCGKTMLAGAVAGECGLNFISVKGPEILNKYIGASEKSVRDLFERAQAAKPCVLFFDEFDSIAPKRGHDSTGVTDRVVNQLLTQMDGAEGLSGVYVLAATSRPDLIDSALLRPGRLDKSLLCGLPTAEDRQDIVRALCSKIRLGDDLLSGDKFAELGRRTEGFSGADLQALVSNAQLEAIHDVLNVAEGQLSTIVSNTVSGKPRNSGSVPSFVKFKYGADDDASSFDGMPKTRSAELAENAAILAKLESIKAARKRARGNAGGDAAFTKGNSVAVASRADTNGKKEANGGGVDVVTVGWKHLTAALENTRPSISAKERMRLEKIYAEFVGARSGEMKDGQGSSEVGGRSSLIVTPERVRLDFNRPLWLFRVQLHGQNGTVSNVTRRFPGPTIYGDRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGM6</accession>
    <name>A0ABR3YGM6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rho-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006776</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000373">
        <property type="protein sequence ID" value="KAL1886992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00159">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="2">
        <location>
            <begin position="256"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="449"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="528"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1072"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1205"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="453"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="545"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="581"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1072"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1095"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1206"/>
            <end position="1221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1886992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1243" mass="137419" checksum="E6DE171ABE12CF28" modified="2025-10-08" version="1">MSRQHISPIASPFPSSQLDDDDTKHKADYENPDDHVRARRIRMLRPRTAPSSSPASTSASLPDSYVPGPLYRGPTDSATTGLQQLQQMSIKNNRSTSALPVSMTTAPALNQGQGYVRGLGLGLRSKSKPQLRPSETWASLNRQENGEDRDEFVARFNEAAAKLDGVHMLEAENFRALQLLTCLEKCEPDAPEQPRRSLLARLFRASTSSPSPKQADTGLKLTKKSVGDYMRPLVKKNMPRYVGLDAMIRISGVSVLSLPYPFLSRPVMLPSCLHETGMYLLEHYMGIPGLFRVPGSYRIVNELYEYYLYAHHGGHDISETIRCEGLPSHIKTGPHDIASAFKRFLNAIPGGILGSVALFEALEEVTYQHNHSSLPRDEQTKVTANLIALALGAVNYQPRRELICGVFGLLALMAAVAKKSVAMGNGEEQLGAQGLGIVFGPLLTGSTPSTETGAHLSGLDSASGSGPSGSGATTPVTVDLEATKRLVEQARNANDIASLLISLWRDIVPELKNNRALEVRIARPFVSNNLQQPQQQQTRSNQYRPFSPSTQISTSFFQQSDNSLSQNPSRIWRASPIPELSSPRETPRSISPEPRSRPQSPLKSARKLFPKAFSSREKNLAAALPHSVHIRRVPSYENSDIECESKPQPRLKHHERIDSRIPTHSPPHLQASAANMPVPLSYIRRIQQQQQDSDLKGGDTITGLPNRPQHQLPARVPIISPRPFAFNFDDEDSTNDSTVPRVVSPDVEVNREARAGDPDRSMSPMEPFHTQKTLKAFKRREVPTSYNNRATAHLPADYENRTPIAYIDGHFQNQSPDQQKQEIMNKPQTPIKAQKQALSLENDMKADIIASEVSIVTETSSTTRTPGRALRTVRSLGALFHRHHGYSLSPVDAVPTLRKGKSEALTHKKLAELEKEASDDVFNTSVDSIAAASTTAVADLDGSHLGNGAVRIKPRHRRLKRVLSNIRDTCNMDQSNRSLDTEIDLDCDTSGDQKLRKSKGALQEDAMVSAIMAAVVGPNTEISKNNVNLETAAARPENRQQKLIIDKAANGSEVFSKTTICRESDASNVDTLESVESATSSGSVRVRQDKNSRGSTTISTATSEASTKAIDTSANKERSGWKMSWRGRTAQQQRQSGSSMSLVHPSLEEVRKLQQEVDSLYQEVAQAKNQENMAVHALKAELRECHNERKIWKVRAHRAEAQLGEMLRREEERERERETKRRDVRKVSAGSSESKYSIREEKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH32</accession>
    <name>A0ABR3YH32_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pre-mRNA-splicing factor 18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_006467</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PRP18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000305">
        <property type="protein sequence ID" value="KAL1887650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.940.10">
        <property type="entry name" value="Functional domain of the splicing factor Prp18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.110">
        <property type="entry name" value="Pre-mRNA processing factor 4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004098">
        <property type="entry name" value="Prp18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014906">
        <property type="entry name" value="PRP4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036285">
        <property type="entry name" value="PRP4-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039979">
        <property type="entry name" value="PRPF18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13007">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13007:SF19">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02840">
        <property type="entry name" value="Prp18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08799">
        <property type="entry name" value="PRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47938">
        <property type="entry name" value="Functional domain of the splicing factor Prp18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158230">
        <property type="entry name" value="PRP4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Pre-mRNA processing factor 4 (PRP4)-like" evidence="10">
        <location>
            <begin position="132"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Prp18" evidence="9">
        <location>
            <begin position="200"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="38"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="47"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="102"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1887650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="346" mass="40105" checksum="B56F81E4C6CD4DD8" modified="2025-10-08" version="1">MDFASLMSKELAKAKPEKSKKYIKKAELEAERVAAYKAEQAAAAQARTEKENAKRKFEEEEAEEKRQREEKRQRLAEQSRQARKEREAEEEAARRKRLGLPELKKADDAEAESRKAQEDGVDDVAEEELAPRLRELGHPVRLFGESHWQRVRRYHRLSMVVTDGPIPTTLQPVEEKDMRLDGSVPQDKVGRKYLFRQLASYFSMVLVEYQRAMERERVDTSASRAAYNTMERCREDMKPLFRKFEKGDIEDSVLQPIVEIVKAAQERRYVDANDGYLRLSIGKAAWPIGVTMVGIHERSAREKLHNGEKGHVMGDEVTRKYLQSIKRCLTFAQVRWPPSDLQQLMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI46</accession>
    <name>A0ABR3YI46_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Stress protein DDR48</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000314">
        <property type="protein sequence ID" value="KAL1887503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="121"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="245" mass="24541" checksum="646CF627372BA9A9" modified="2025-10-08" version="1">MFGFGDSDKDNNRRGNDDNGSNTKRSDRDGSGRDEDNTSSSYGNTGSSRGSYGDNDTTTSSGYGNTSGSGRAGYGDNDNSTSGYGNSNSSSRGSRGDNDTTSSSGYGGASSRSSRDDNDNDSYGSSGRGNNSSSYGSSNDDNSHGSSGRTSGGLGNDDDNSYGSSTRTSGRGNNSSYGSNDDNDSSSYGSSGRGSSGRSGNDDSESFGSSDRTSGRGNSGSYGGGNDNGSSGRGGSGSYGGNNDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIW2</accession>
    <name>A0ABR3YIW2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Retrotransposon gag domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000300">
        <property type="protein sequence ID" value="KAL1887726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005162">
        <property type="entry name" value="Retrotrans_gag_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03732">
        <property type="entry name" value="Retrotrans_gag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Retrotransposon gag" evidence="2">
        <location>
            <begin position="25"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="198" mass="22364" checksum="473E0F675F643C84" modified="2025-10-08" version="1" fragment="single">MGEANESAGGELQRLAEKAGSTVAEVWKVLDDHFEDPLFRARASERLENLEQRNKTLDRYIFEYRDLLQQAGGDGYPEDVKIRGLMRGPNDALYERMVTIPMSSTLTSQIESLRGVSQRMEEVTQRKSRKRKPTLFTQPVKIDEGDPMDIDVNVSQVRGGPQRPVRGSEPGLPTDNAYRGKTSKWVSREVLQARKEAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ25</accession>
    <name>A0ABR3YJ25_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006418</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000297">
        <property type="protein sequence ID" value="KAL1887786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="701"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="918"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="702"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="719"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="751"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="807"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="918"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="939"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="960"/>
            <end position="974"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1047" mass="111188" checksum="396E53173EF7F0B8" modified="2025-10-08" version="1">MVSSTSASPQPRSLSLVGPSFDQSSNSYVHQPLAQMSNLPHSQAQAQKLDLVTSQTAKSLAPGSSPGTPRPPRYSAVRHSRDIAVTLARRASLLSVAAGTTGTTDTTNTSEKGGKNSGMADGCRQFACLASSGNVLDNHKIDADAQGSGLGGTVVAGYNADTSGQACIPSSNTPAFSERLPVFTGLPRSSSAPPTSLPRASSMVSQDPVPVAQAVPAILDQSQACLKQICYQNNGEDNEDIIQLCSPLTTLPAEFPLYEHENKVILLSPSGNQQDNRQQGNPNSASSSADDADRAALNQPLTILSPSPLPPLPSPSFLSSLSQRPTSSPVSPYYVLQPRTTLPRPQALVFDGTGLDCSPYMPVPLPPSWLSPTARVFSETTGSPSTATGTDVGLSSFSPSPFATTARINACGEARLPAGPLLKGGCSLPCARAAASATTTHLQLQSHQSSRFPWASTSSRFSAWSLSPATCSEQDGEEKETTVNLGLHLVGEEQQELEATVSHQLSRQYETAKLVLGGEEMQAAAKNENAETETQAQTQTQLIGYSHSVFLYKRPTERDPSCRCDSSHSETSIQSVQPQNDCHTVSLSLPLPLPFVPTLPPTLAAIPAHISDIEPPSPAFSFCSEDLNLRPLSAASPVPSTHPSPSLAAGSRMTSLYIPDSLNEMGSGFSTSWGTPKSPRPAAFLNACSCAITMPKSPNAMDFTTQSSSPSMLSPRKVSAASTTSSVSSAPSSSFSSSDTEDRSSSTITTCSPPFTPRNSLFSGSQSNLHVHMSPFQPYRSPPHPKHLSQPVETAHTPVRQPMRPYSNSSVVPSNTLSSSNAPAMELAANVKSLPPTPSSHLSPPPPPPPAYQCSLLPWSPSNQAMPRSMTVAEPQVSYFDTDTEEEEEEEADLQDARDRARAISRLFGPKRKSLHYATTSGSISSATPGSRMSATESSRAREKEAKTRGGKAEKRKSKDAKSDKSDSEQHSDSEPGTPLDLATAGDRNSFLQWTNGQMLGMFTHIRLSSSFMSKKQKKERRKQNIKKHIRVLHETGTDLGTSATIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJJ8</accession>
    <name>A0ABR3YJJ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 13">Ribulose-phosphate 3-epimerase</fullName>
            <ecNumber evidence="8 13">5.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">RPE1</name>
        <name evidence="14" type="ORF">Cpir12675_006330</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>D-ribulose 5-phosphate = D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13677"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="EC" id="5.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Carbohydrate degradation; pentose phosphate pathway; D-xylulose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 13">Belongs to the ribulose-phosphate 3-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.1" evidence="8 13"/>
    <dbReference type="EMBL" id="JAWDJO010000283">
        <property type="protein sequence ID" value="KAL1888013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004750">
        <property type="term" value="F:D-ribulose-phosphate 3-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00429">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02227">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026019">
        <property type="entry name" value="Ribul_P_3_epim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000056">
        <property type="entry name" value="Ribul_P_3_epim-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004076">
        <property type="entry name" value="PRK05581.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11749">
        <property type="entry name" value="RIBULOSE-5-PHOSPHATE-3-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00834">
        <property type="entry name" value="Ribul_P_3_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001461">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01085">
        <property type="entry name" value="RIBUL_P_3_EPIMER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01086">
        <property type="entry name" value="RIBUL_P_3_EPIMER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="12" id="KW-0170">Cobalt</keyword>
    <keyword evidence="11 13 14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00009541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00013188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00013920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR001461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1888013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="249" mass="26891" checksum="075B3A162C8DAC13" modified="2025-10-08" version="1">MAPSAIIAPSILSADFADLGADCSRTIEKGADWLHVDIMDGHFVPNLTFGPPVLTKIRKHVKPPTEKHGKGTFDCHMMIAEPKKWVKEFKKAGCDLYCFHYEAAFSSAAEEPEAKTEDMTSPKALIKYIHDQGLLAGIALKPSTPVDVLWEILESPDANERPDMVLIMTVEPGFGGQKFMASELPKVQALRERYPELNIEVDGGLGPGTIDQAADAGANVIVAGSAVFGAKNPAEVIALLRDAVAKRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLV0</accession>
    <name>A0ABR3YLV0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Guanidinobutyrase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_005896</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arginase family. Agmatinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000228">
        <property type="protein sequence ID" value="KAL1889173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11592">
        <property type="entry name" value="Agmatinase_PAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.10">
        <property type="entry name" value="Ureohydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020855">
        <property type="entry name" value="Ureohydrolase_Mn_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358">
        <property type="entry name" value="ARGINASE/AGMATINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358:SF26">
        <property type="entry name" value="GUANIDINO ACID HYDROLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036979">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00116">
        <property type="entry name" value="ARGINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01053">
        <property type="entry name" value="ARGINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046345607" description="Guanidinobutyrase" evidence="5">
        <location>
            <begin position="18"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1889173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="395" mass="42689" checksum="913787ED6B9C119E" modified="2025-10-08" version="1">MGFKHFLILAALGFGSAHKDHHHAQASDDARADVSLEEKWGTDWGFAGIQTFAHLPHVKCLVEDKYPFDIGVIGVPFDTSVSYRPGTRFGPRALRSGSSRQTPFRSFNHRAGINPYSSWARIVDCGDMNVSPFDNGLALRQMTEGYAELSKRFPTAPAHTGGKPKLVSLGGDHSIALPALRALKNAYGRPINVLHFDAHLDTWHPAKYPSVWVPIPAPGEAFPQSFFTHGSFFWMAHSEGLIANGSVHGGIRTRLAGVDDADFRDDTEQGWLRILADDIDDIGVEGVINTIMGRLGTENPVYLSVDIDIIEPGLAPGTGTPEPGGWTAREFIRILRGIEGLNVVGADIVEVSPSYDDAGETTALLGAQIAFEIITSMVKKGVEAAGAATESHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMI3</accession>
    <name>A0ABR3YMI3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">VPS37 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_005935</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000232">
        <property type="protein sequence ID" value="KAL1889050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.660">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037202">
        <property type="entry name" value="ESCRT_assembly_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029012">
        <property type="entry name" value="Helix_hairpin_bin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009851">
        <property type="entry name" value="Mod_r"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13678">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13678:SF2">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07200">
        <property type="entry name" value="Mod_r"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140111">
        <property type="entry name" value="Endosomal sorting complex assembly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51314">
        <property type="entry name" value="VPS37_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="5 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="VPS37 C-terminal" evidence="8">
        <location>
            <begin position="153"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1889050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="245" mass="26962" checksum="291911EDDCAC7A5D" modified="2025-10-08" version="1">MSGPPPPVLPPKLGSNGPSHHGSPLVAADYAQRQQLQASNGASDGIEVAHTVSEMDGSSSGNVADPGPKWIPTILEDKSTRDLTDILRSPKLLQALNDASTASAPSVAAPRATLHSLLLENTQTAQHLLQLEERLAHERATANAQLLTAKKLERDWAEKQREVDSALERFMPAALYQRLGQGVVEQQAVCEALEESFVDGQGEAGLASERETMEWIKRYKEAKIVYWRRKEQKDRWDEGRVGGWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMI7</accession>
    <name>A0ABR3YMI7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ATPase of 26S proteasome regulatory subunit 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RPT2</name>
        <name evidence="8" type="ORF">Cpir12675_005904</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000229">
        <property type="protein sequence ID" value="KAL1889122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 8" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="7">
        <location>
            <begin position="234"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="16"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="456" mass="50592" checksum="A94901B0B89C83B1" modified="2025-10-08" version="1">MGQNQSGMGGGSEGGDSSKDKKKEKPKYEPPPRPTTRVGRKKRKTGGTSAAAKLPAVYPTSRCKLRLLRMQRTHDHLLLEEEFVANQERIRKANQVGDGNTLEDSDRLADERGRVDDMRGSPMSVGTLEEMIDDDHAIVSSTTGPEYYVSIMSFVDKDLLEPGASVLLHHKSVSIVGVLTDDTDPLVSVMKLEKAPTESYADIGGLEQQIQEVRESVELPLLHPELYEEMGIKPPKGVILYGAPGTGKTLLAKAVANQTSATFLRIVGSELIQKYLGDGPRLVRQLFQAAAENAPSIVFIDEIDAIGTKRYDSTSGGEREIQRTMLELLNQLDGFDDRGDVKVIMATNKIESLDPALIRPGRIDRKILFENPDQNTKRKIFLLHTSKMNLNEDTDLDEFISQKDDLSGADIKAICSEAGLMALRERRMRVQMSDFRAARERVLRTKQEGEPEGLYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMW9</accession>
    <name>A0ABR3YMW9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ca(2+)-dependent cysteine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MCA1_3</name>
        <name evidence="7" type="ORF">Cpir12675_006061</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000247">
        <property type="protein sequence ID" value="KAL1888724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050452">
        <property type="entry name" value="Metacaspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104:SF30">
        <property type="entry name" value="METACASPASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104">
        <property type="entry name" value="METACASPASE-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="Caspase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="Peptidase C14 caspase" evidence="6">
        <location>
            <begin position="130"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="438" mass="48313" checksum="E6F8148BC32B6993" modified="2025-10-08" version="1">MSGYNYPHYDGTTPLPNGVSPQYISSPGYYDQQQQYQQQVPAAAYQTYPQNSEAGFNYAATPGQQVYQQYPQNNLIASFQTATPMTYAPNTMAGPSSGVVDPGVYATSGGADATAPPPSYDFKLPPCQGRRKALLIGINYFGQRGQLRGCVNDVRNMSAYLTQQFGYKREDMVILTDDQHNPIGHPTKHNILRAMHWLTKDAKSGDSLFFHYSGHGGQTRDPESEDPEGYDEVIYPVDFRQTGHISDDEMHRILVKPLCQGVRLTAIFDSCHSGTALDLPYIYSTQGIMKEPNGVQAAGTELLQSVSAYTQGQGEAETVKRGFIGLLKRATAGDESMQRSKLLKSSEADVVMFSGSKDNQTSADSMISSQPTGAMSWAFITALRKNPQQSYVQLLNSIRDELATKYTQRPQLSCSHPLSKHHPLMIKQYKAPSTRTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQF1</accession>
    <name>A0ABR3YQF1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005313</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000178">
        <property type="protein sequence ID" value="KAL1890589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="492" mass="52708" checksum="36F37B8193FB7248" modified="2025-10-08" version="1">MDFIAPPPRSLATPGHPTPTENGKAADIAFPPFQHIDNYSDGSGSSIGSEELYEEINSGRARNMGTCTMNPLLNPFLNVNPALLNPTANHQGATNMGSNASSDPSYHRNSSIIEEIDGDDLDAALEPLLLLVDKFRLQNDAQLAAVQNHLAGLDSKFIIMDDKIMALSGQLKNIEKMLVRVLTPNGGVSPPETKDPAICSSAAVLGSVSQPTSPRQGLRGAARGPWRAQASLGTRVASIAAPQQGPGRVPTILQKIWTRQHLAQRAQEARQQKLGHCDMHGVGMQPAMGQSSAGQVPLPQAGMETEAQEYTKASVASPYNSAAPSAYTPADYPTITIGNRTVTKVPATRNLQIPRSKTATPAKDAAASDAYMMKPPPNGKDQNFQYSVMARNLTIATANRTAYNIDKNCRLYPLLDIRTGEPIPNFPKDTTEMVAVNDDKCSRILEAIGQSMSGTATERRQRALMHTIVGLGLSQFREALGDGQGVNGEVNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQN7</accession>
    <name>A0ABR3YQN7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005494</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000190">
        <property type="protein sequence ID" value="KAL1890201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038872">
        <property type="entry name" value="Put_GTT3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41807">
        <property type="entry name" value="GLUTATHIONE TRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41807:SF1">
        <property type="entry name" value="GLUTATHIONE TRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="334" mass="35929" checksum="32A8878A3615D29D" modified="2025-10-08" version="1">MSTNAWLRAQRKGELQDLAIALGLDVSQPLKKSDLEALIETHVLSNDASLVDNDRLIGFWNSRARSAGSPVKREPVDVSEPKPPSTALRRRTTRALDELSNESLDQDSASPLALLPRTPARALALASSRLHLPSTPASVQRAVDRSVELFQDGVVAVQDSTLAEATVTTRSTLSTVPNILLSIAVFEAYFLRPAVLPDALWLTTPAVPALYLPAIPIVLPNLTTMLSASFWGPVFAWLATTVFVPLVFAYFYNLSANAASKRLRNKYLFDPLSFSIAKAVLSFAVFAQGVSFSGLVHQTAIARVNAAVYGGWQGLLVGAGISGLAAFYEAILSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQX0</accession>
    <name>A0ABR3YQX0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transcription initiation factor TFIID subunit 10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_005659</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TAF10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000205">
        <property type="protein sequence ID" value="KAL1889774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07982">
        <property type="entry name" value="HFD_TAF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003923">
        <property type="entry name" value="TAF10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21242">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21242:SF0">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03540">
        <property type="entry name" value="TAF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="190"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="8"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="251" mass="25406" checksum="AFDCE41149126EC9" modified="2025-10-08" version="1">MPVPKQESPAPVSSATAPTATNAGPVATAPSNNGVLAVPLTVAAAGNTTNNNVAVMANGTGAPATSGDEATASEGAGAAVIAPTLDTSEAVIPESRLPTRKDSSLREFLSKMDDYAPIIPDAVTNYYMTKGGLPPAPQTDPRLAKLLALATQKFIADIAADAYQYSRIRASNTTNNPMANLAGGGFPMAGQAAGQPGAKDQGRGGPLGIQRPGYGGGGSGSGQNRTVLTMEDLGMAVAEYGVNVKRSEFYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR93</accession>
    <name>A0ABR3YR93_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_005321</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000178">
        <property type="protein sequence ID" value="KAL1890597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09630">
        <property type="entry name" value="CDH_like_cytochrome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.410.10">
        <property type="entry name" value="Cholesterol Oxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015920">
        <property type="entry name" value="Cellobiose_DH-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053208">
        <property type="entry name" value="GMC_Oxidoreductase_CD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47190">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47190:SF4">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16010">
        <property type="entry name" value="CDH-cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046342756" description="Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein" evidence="3">
        <location>
            <begin position="20"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="4">
        <location>
            <begin position="478"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="748"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="756"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="804"/>
            <end position="822"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1890597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="822" mass="85559" checksum="175007E0FE9032C5" modified="2025-10-08" version="1">MSKFLYAAGLMASAAMAQSLEPYTDPLSGIKFGRHTDPASGFSVGLALPQTIGTDFIGQITVPVSAGYGAISLGGSMTNTILLVAQPSGSDVVASLRTASGYTNPEVLTTNSTFDIMPIKEGISVSSTAFTYTFLCKGCITGDDRSWISTDTTATIGWAYSNEALAEPSNPSGALNYHGSGFGLFGAPFANATSTEYDTWAALATTTSYGSTPSTSTPTYGNSTDATVSSETYDYIVAGGGVAGLIVAERLAESGKSVLLLERGAKSSASTGGDAFVNWNSSITQYDVPAMAYYLSTAKQTGQYCTDTASMAGCILGGSGMINAMMWVKPNSGDFKNWPAGWNWDDVKASADALYERTPGTILPSADGERYDQAAYNVVSEFLSGNGFSSVDALNDVESKHDIFSYPPWLIKDGLRGGPVHDYLPLAEAMSNFKLTINAKVIRVIRSGSTMTGVEVEVDQQRQIINLNAGGAVVLTAGALSSPRLLINSGIGPTEQIETVQSGSVAVTLPDKADWINLPVGQGIKDHPIFTVKLTVKTPLQSLPSTAFTQPNDTSVELFSQQSGLLSQSGQRLNFWTSVTNADNTVRYIQGTCNAPSDNTIQMKIYLTHGLTSSGSLVMETDGSTKFGVQPYLTTDGDKEAIKSFMQRLIDFTKQSDSTLSLPSNATAESLIASHATGSHYVASAAMGASNDGKSVVGTDTKVWGTDNLFVADASMHPDLPVGNTQAIVMVAAEQAAKAILAADKGSGTSYGSGSGSSTSVATPAAPYPTGTGSTPAAPYPTGTGSTPAATTTGTAGSKAPSSCKRRRAARRAARLAARRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRV7</accession>
    <name>A0ABR3YRV7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_005301</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000177">
        <property type="protein sequence ID" value="KAL1890669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="3">
        <location>
            <begin position="412"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="165"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="247"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="178"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="259"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="315"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="484" mass="54094" checksum="3FD9227EEA3753EB" modified="2025-10-08" version="1">MRHPDFPTPTPISQDAIHCTNTATTQTYTQQYTTQRPQSRVVIDIPHMPSPYIPGSGPVSHDATIVPISDSTAYIIDQVFLSGGFAADGKLRPKSLAWLIGFRDRPAARIVVRAYQIYDYVSPRELEEYEYRQWLQREEEKERLTQDIGDGFSAEIDAAVVRKLAKRAPGRPGESHPRKVRKNNKAKRKPGHRDLTTPGLQTPSEVLSEVDVRKTMAMVIPPVKTTVSLISVVPKKRKISALGEAAAVPGSETTEREGTVSQNNFSTDGFETEDTKIHSSSQASPYKRVMRGSESVRDSSTDILAELKPPQKTHNINDKVTFDQAGARDRDENNNEESNTTPISNAKPADTTLIQAKRSNWVRVNGSSVAHLVQTTENRKAPTGENLDQQTQGLENDFKNGVVHEELGEDEYIVAAIEDVKNQRGKLLFLVRWAGNWPPDQQRTWEPYENINEVMTTSYLLNNPIQAKAAKASNFISRLTKREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRX1</accession>
    <name>A0ABR3YRX1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Glucose-6-phosphate 1-dehydrogenase</fullName>
            <ecNumber evidence="3 9">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ZWF1</name>
        <name evidence="12" type="ORF">Cpir12675_005285</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15841"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="1.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glucose-6-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="3 9"/>
    <dbReference type="EMBL" id="JAWDJO010000176">
        <property type="protein sequence ID" value="KAL1890684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00966">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019796">
        <property type="entry name" value="G6P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022675">
        <property type="entry name" value="G6P_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00871">
        <property type="entry name" value="zwf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429:SF0">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02781">
        <property type="entry name" value="G6PD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00479">
        <property type="entry name" value="G6PD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000110">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00079">
        <property type="entry name" value="G6PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00069">
        <property type="entry name" value="G6P_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 9" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="6 9" id="KW-0521">NADP</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-6-phosphate dehydrogenase NAD-binding" evidence="10">
        <location>
            <begin position="20"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-6-phosphate dehydrogenase C-terminal" evidence="11">
        <location>
            <begin position="199"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1890684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="505" mass="58208" checksum="DFACFE58DEF08889" modified="2025-10-08" version="1">MAGHMNDPASIELKDNTTIVVLGASGDLAKKKTYPALFGLYRNQFLPKDIRIVGYARTKMDHDDYIRRIRTYMKTPTPEMEQQLDDFCKLCTYVSGQYDKDESFQNLTRELEVLEKGRPENNRLFYMALPPSVFTIVSQHLKRCCYPKNGIARVIVEKPFGKDLASSRELQKSLEPDWKEDELFRIDHYLGKEMVKNILILRFGNSFLGATWNRHHIDSVQITFKEPFGTEGRGGYFDEFGIIRDVMQNHLLQVLTLLAMERPVSFSAEDIRDEKVRVLRSIPAIEPKDVIIGQYGRSLDGSKPSYKEDDTVPKDSRCPTFCALVAYIKNERWDGVPFIMKAGKALNEQKTEIRIQFKDVTSGIFKDIPRNELVMRIQPNESVYIKMNSKLPGLSMQTVVTELDLTYRRRFSDLKIPEAYESLILDCLKGDHSNFVRDDELDASWRVFTPLLHYLDDNKEIIPMEYPYGSRGPALLDDFTASYGYKFSDAAGYQWPTTSALPRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS88</accession>
    <name>A0ABR3YS88_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNL-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_005062</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000160">
        <property type="protein sequence ID" value="KAL1891216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024158">
        <property type="entry name" value="Mt_import_TIM15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007853">
        <property type="entry name" value="Znf_DNL-typ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20922">
        <property type="entry name" value="DNL-TYPE ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20922:SF13">
        <property type="entry name" value="DNL-TYPE ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05180">
        <property type="entry name" value="zf-DNL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51501">
        <property type="entry name" value="ZF_DNL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNL-type" evidence="6">
        <location>
            <begin position="46"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="10"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1891216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="135" mass="14824" checksum="30542BDFD729DE73" modified="2025-10-08" version="1">MKYSSSPNSSSPPSPSQPPSNAPAPSSPPSYSELSPEASQVLQRKLQEPHYQLSFTCVPCDHRSTHVVSKQGYHHGSVLIACPNCNNRHVISDHLNIFGDRQVTVEQLMQEKGEIVRKGVVDANGDVEFFGEEKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSP9</accession>
    <name>A0ABR3YSP9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004983</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000155">
        <property type="protein sequence ID" value="KAL1891369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045439134" evidence="2">
        <location>
            <begin position="18"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="192"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="254"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="284"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="340" mass="33518" checksum="33FB7D2D1C8F9BBE" modified="2025-10-08" version="1">MKASIIFLAASAALTQAAAITRDSLPVVERAFQVTARTAEDKHNAIVGDSTPVHIRQNKGSGDNSLSQVLSTFLGAEQAAPVLEFLGQLNGNANPGGNTGGNRGGTPANGRTPANGGTPGGAGRGRGRNRRPVRTTVPPAGGGAPEPSFPLVFGTSQATPSPIFLTLTGTGADAAAPTGANNTVARGNLQVPTEAAPTPTPAPVSTKTKTPEKTPNPTPAPEAAEAAASGPGLIVFSLPPTVRTTILPPPPVEAPAVTRASSSSSAPPALPAVQAPPAQPTPSTPSQQPTQAPEATPTVTPPAVLPSKSNTEAEMGGVPPDLSGVALSSALNLGALGGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT61</accession>
    <name>A0ABR3YT61_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_004935</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000152">
        <property type="protein sequence ID" value="KAL1891563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF6">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G14560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="313"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="353"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="1"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1891563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="474" mass="50606" checksum="D65B617B15370598" modified="2025-10-08" version="1">MIQSKVAEDLDADEEVMWFAGAYLIALSALTPVIGRLATIFVPRNIVIPVSLLVAAGSALTASATTFVRFTIGRVVTGMGAAGVFTLSMIFVLQLTSKERRGMYMALVNMGFTAGLSFGAIMYAAGAGVYLSVPESSQPRKKLNGGMSAAQKLASIDYFGVVALTATISLFLYALIGDIRPYCIALSFVFLGVFVLWECRFATDPIIPLKILSSKDVLCTCFAQLIFVSTRWSLLYYGPVFMLVVKGFSLSVSGSILIPTNIGFGGGGLLIGWLHIRHHGSFWLSSILSLAIFCLTLVLVASSGSTSSPSWLFVLYVFLNGLATGGGVNYTLAHMLHLTSPDVHFVSTSLLGMFRGFGGSFGTAIGGGYFMRLLKSLLTEEFARLDGGVMSPRHEDLVVKLAGRPSYVFDGGLSANEEIIARSGYAAALQQTWRMAALVGLTSIVLQGMCGWRAPDGINEVGDGDIADNERSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTF1</accession>
    <name>A0ABR3YTF1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Neutral ceramidase</fullName>
            <ecNumber evidence="3">3.5.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_004912</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>an N-acylsphing-4-enine + H2O = sphing-4-enine + a fatty acid</text>
            <dbReference type="Rhea" id="RHEA:20856"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:52639"/>
            <dbReference type="ChEBI" id="CHEBI:57756"/>
            <dbReference type="EC" id="3.5.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the neutral ceramidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.23" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000151">
        <property type="protein sequence ID" value="KAL1891571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2300">
        <property type="entry name" value="Neutral/alkaline non-lysosomal ceramidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006823">
        <property type="entry name" value="Ceramidase_alk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038445">
        <property type="entry name" value="NCDase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031331">
        <property type="entry name" value="NEUT/ALK_ceramidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031329">
        <property type="entry name" value="NEUT/ALK_ceramidase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12670">
        <property type="entry name" value="CERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12670:SF1">
        <property type="entry name" value="NEUTRAL CERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04734">
        <property type="entry name" value="Ceramidase_alk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17048">
        <property type="entry name" value="Ceramidse_alk_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0746">Sphingolipid metabolism</keyword>
    <feature type="domain" description="Neutral/alkaline non-lysosomal ceramidase N-terminal" evidence="5">
        <location>
            <begin position="49"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="Neutral/alkaline non-lysosomal ceramidase C-terminal" evidence="6">
        <location>
            <begin position="623"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1891571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="774" mass="83748" checksum="A03805C27F68DE5A" modified="2025-10-08" version="1">MASSLLGHPLGDHRNSSQVQVQVQVQVQPQPQPKPQHTENGQTRGHNIFLAGAGKADITGPVVELNMMGYADSSQIGTGLRQRLYSRAFIVGETHNPSARVVYLVLDTHSGDTAVRNGIMEGLHALGSPYTELYGSQNIAVTGTHSHSGPGGWHNYLLPQITSFGFDRQSYQAIVTGAVLSIKRAHDSIEPARLGFGSTKLQDASINRSLFSYLTNPEEERAQYNKTGNGTDHKFTSGTQDDGSVETDLKLLRFSRVSDNKTMGVLTWFPTHGTSMLANNTLISGDNKGVAAALLEKKLLQEAPDSITESFVAGFSQAHVGDVSPNILGAWCEDGSGSRCSPVNSTCSDGRAGSCHARGPRFRVADNGASSCYEIGRRQYAAARKLTMAPLDGEAPDALKPITGGGTVRAFHAFHDMSNFEFISPDEPERVKRTCPAALGYSFAAGTSDGPGGLDFTQNDHSGADKSAAWKVISSLIKIPGAEQVACQAPKPLLLDVGEVVRPYLWTPNIVDIQVLRIGNLMVVVSPGEASTMAGRRWMRAVEKEARDALESTPDVTNVEVVLGGPANTYTHYISTPEEYALQRYEGASTLYGPHTLAAYINRTLEYLPLLFDTAKTPLAAAAEIGPLPPDTRNASLHFVAGVVFDSHPFFTAFGDVISDVAPSSVYYAGDTVQATFIGANPRNNLRLEGTFAAVERMISPGVWRTVRDDSDWDLVYNWKRTSSIRGTSKVMLQWHLPDDVERGCYRLRYFGDAKSLSGRITSFSGTSSEFYVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU02</accession>
    <name>A0ABR3YU02_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glycogen synthase kinase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">gsk3</name>
        <name evidence="10" type="ORF">Cpir12675_004800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000145">
        <property type="protein sequence ID" value="KAL1891796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14137">
        <property type="entry name" value="STKc_GSK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050591">
        <property type="entry name" value="GSK-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039192">
        <property type="entry name" value="STKc_GSK3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24057">
        <property type="entry name" value="GLYCOGEN SYNTHASE KINASE-3 ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24057:SF0">
        <property type="entry name" value="PROTEIN KINASE SHAGGY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="36"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="395" mass="45143" checksum="C259445F2F57E44F" modified="2025-10-08" version="1">MSSTSRPTPFNNLRMGEVVREKVQDGVTGETRELQYTQCKIVGNGSFGVVFQTKLTPSGEDAAIKRVLQDKRFKNRELQIMRIVRHPNIVQLKAFFFSNGERKDEVFLNLVQEFVPETVYRASRFFTKMKSTMPILEIKLYTYQLFRALAYIHSQGICHRDIKPQNLLLDPSTGILKLCDFGSAKILVEHEPNVSYICSRYYRAPELIFGATNYTTKIDVWSTGCVMAELMLGQPLFPGESGIDQLVEIIKVLGTPTREQIRTMNPNYMEHKFPQIKSHPFHKVFRKADASAIDLIEKLLEYTPTERHSAIDAMIHPFFDELRDPATKLPDSRHQSGQLRDLPALFNFTHHELSIAPTLNNKLVPAHIRPVLLAQGLDIDNLTPLTKEEMAARLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU70</accession>
    <name>A0ABR3YU70_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000144">
        <property type="protein sequence ID" value="KAL1891906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="88" mass="8963" checksum="2C99BB2E38A272F0" modified="2025-10-08" version="1" fragment="single">AQAQAQAQAQAQAQAQAQAQHKAQLQALAQQSTPTQTPAQPAKQPTSQVSTPKLPPQTPVLQQTSQAEGAVAQRAASVVSGSATPKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUF1</accession>
    <name>A0ABR3YUF1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_004734</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000141">
        <property type="protein sequence ID" value="KAL1892013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017984">
        <property type="entry name" value="Chromo_dom_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008251">
        <property type="entry name" value="Chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023779">
        <property type="entry name" value="Chromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051219">
        <property type="entry name" value="Heterochromatin_chromo-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22812">
        <property type="entry name" value="CHROMOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01393">
        <property type="entry name" value="Chromo_shadow"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00504">
        <property type="entry name" value="CHROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00300">
        <property type="entry name" value="ChSh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00598">
        <property type="entry name" value="CHROMO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="5">
        <location>
            <begin position="85"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="152"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="55"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1892013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="267" mass="30567" checksum="4AA370576D29F5A0" modified="2025-10-08" version="1">MPRTINDDDSNVGFVATRPRSASRSTTKYSRSREGSGGYASEEEGDPKRPNGRGKKADMVVEPERDDREGDEGEAESEELADDEFIVEKILDHMVDQGVVKFRVKWEGYDDEEDITWEPEGTLREGAEVILEEYLASYGGIKKIISEASDVAKNKKRNRRSTTAAKVEKPPKRARKEHPLETPAPAPLREKQWRPPNGSWEDHIETIDVCDEADADTGKSRLVVYLNWKNGRKTKHNTEMVYKRCPQKMLRFYENHVRILKTNSDNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUS3</accession>
    <name>A0ABR3YUS3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Suppressor of anucleate metulae protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_004894</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000150">
        <property type="protein sequence ID" value="KAL1891585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050869">
        <property type="entry name" value="H3K4_H4K5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197:SF251">
        <property type="entry name" value="EG:BACR7C10.4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SET" evidence="6">
        <location>
            <begin position="2"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="7">
        <location>
            <begin position="48"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="122"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1891585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="551" mass="61245" checksum="995FBB0BD40D92BE" modified="2025-10-08" version="1">MGNYKISTTETRGRCLKATTAFQPGDTIGLFTNPVFSIPSSGQLSSQCSHCLRSDCELRLCTGCRAVSYCNVNCQRGAWKPMASGGGGHKHECPVLKLARERGGGRVLPTPTRALVAVMVNGKVAEERIKELEGNVNEFRQDVRGWEDMRLQAYMALSYSKIAGPDKTDKYAEMLCKILTNTFNAYDPDVSESSVFLEPTLAMANHSCIPNATVQIEGREALLIAERPIAADEEIFISYINYSNSLKYRRVDLEKYHFTCVCPRCTNDLDIYTVCKSYPSLSANGYSLVSAASLKSPEINRAIPESLERTYGNLQDDYKEFETSLGGPSKDTLKRGFAIVKPLVQANLWAMLPMPAFLNECVAYWKVSSEYPEDSIVALPLSCLIASRVIPATSPLPWSTNRLRTALFLCNTLYNAAYSVTDVKAKLDRLCIRVKLDDKRRHTIANAHEMSMNYLVAGMILHYKGHLHPESFTIHAANQLMTGFRASRGFENLDTLPEGSDSSGRMAAVLSWDEDKLRGRPWEAFWKASVVDVVEALAEVGARFIEQELGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUV6</accession>
    <name>A0ABR3YUV6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_004631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000136">
        <property type="protein sequence ID" value="KAL1892163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1892163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="182" mass="21052" checksum="46ECE2D423352AD5" modified="2025-10-08" version="1">MDGLNQLRQMRVAELLEDFRVLQYHIAHAPQDPSEMVDYYTEGWIALREAHLDGRHILDCAADTRVPRARGGPEEQEKAELQQVHLDAFSRRHVGQKIHLRQAAAMRWIEYRARILEGDTTLAATQHALAMLDQQLRADLDALTDEAIYVQLHTHDTSLNRWTGEDPSLRRVKAWIESRSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV70</accession>
    <name>A0ABR3YV70_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Septin-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_004622</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000135">
        <property type="protein sequence ID" value="KAL1892266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="3">
        <location>
            <begin position="135"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="487" mass="54936" checksum="45B936EB7EA3142B" modified="2025-10-08" version="1">MLLRRSKSSDLKSKKAREQQELLRQQQQQAIPKMPPKLPEFNKAHDQLSNAFGATHLSHDAVSIASVPTEPYSARTSMEPGRYVVTKLPPPPVPQSIPFDPYARTESMTHRGRYSYASSAISTINSPRRVRRRKDPTPFNILVIGSRNSGKTSFLEFLKTALALPPKKRSRKMEDDEPVYRAPQGNFIPHYLETEIDNERIGLTLWDSEGLEKNVVDLQLREMLAFLESKFEDTFTEEMKVVRSPGVQDTHIHAVFLVLDPVRLDQNISASRAATNSFKGPHARILGGLDEDLDLQVLRTLNRKTTVIPVISKADTITSKHMAVLKKSVAESLKRANIDPLSSLGLNEDGSDSSCIDETDEYEIATSNGAPNNVNYETIGHAIGDPNEFPSNGAISDPSHRNSVSDETPMLPLSIISPDLYEPGVMGRQFPWGFADPYNEEHCDFIRLKEAVFSEWRGDLRELSREQWYEGWRTSRLKLRTSNSIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVA2</accession>
    <name>A0ABR3YVA2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytoplasmic GTPase/eEF2-like protein (Ribosomal biogenesis)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RIA1</name>
        <name evidence="4" type="ORF">Cpir12675_004773</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000143">
        <property type="protein sequence ID" value="KAL1891914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01681">
        <property type="entry name" value="aeEF2_snRNP_like_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04096">
        <property type="entry name" value="eEF2_snRNP_like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01885">
        <property type="entry name" value="EF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16268">
        <property type="entry name" value="EF2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16261">
        <property type="entry name" value="EF2_snRNP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1430.10">
        <property type="entry name" value="Yeast translation eEF2 (G' domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056752">
        <property type="entry name" value="EFL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF3">
        <property type="entry name" value="ELONGATION FACTOR-LIKE GTPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25118">
        <property type="entry name" value="EFL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="3">
        <location>
            <begin position="17"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1058" mass="116988" checksum="E890649008058393" modified="2025-10-08" version="1">MPVVSAEKLANLQQHSADIRNICILAHVDHGKTSLTDALLATNGIISPKLAGKIRYLDSRPDEQLRGITMESSAISLYFSMMRRAAPEAEPELKEYLINLIDSPGHIDFSSEVSTASRLCDGACVLVDAVEGVCSQTVTVLRQAWVEKLRPLLVINKIDRLITELKMTPSEAYTHLSKLLEQVNAVLGSFFQGERMEEDMNWREKMDAKVAAAMTKDSTSQTDGDDKFQEKDDADIYFAPEKNNVIFSSAIDGWAFTVRQFASIYEKKLGIKRGHMEKVLWGNFYLDPKTKKILAQKHLKGRSLKPMFVQLVLEPIWTVYNATMGGDHGKGDPELLEKVLKSLSITLPNHILRSRDPRMCLTSVFASWLPISVAVLVSVVESLPSPEQAQAERLPALLEDSPGSESISTAVKNAMVNFKTQKDEPVVVYVSKVVSIPESELPKNKRKPGTMSSDEARELARKKRAEFARKQAAESQNDVESVIYSLEDVNLDRHAPELEEKTIDPEHLIGFARIYSGTVSVGDKLYVVPPKWSPAQSGSAEKLREIQVEALYMFMGRNLESLESVPAGCVFGIGGLDDNILKSGTLCSVRDGAPNLAGVNMAGQPIVRVALEPVNPMDLDKMIEGLKLLVQSDPCAEYEHFETGEHVLLTAGELHLERCLTDLKERFSRCEIQASAPIVPYRESIVRDKEMRPPANKELGRGGVIMATSSKQVTISLRVQPLPVEVTSYLRKNVDSIKKLYSDKKADKAGNSDDIESKEGEDIEAGFVTSQGLSTTELREGLHKALEEGKGREAWKGLVDKISSFGPRRIGPNLLIDATADQVMSHIFAPANSPPSNDVLGPRHFGDKISYGFQLATNQGPLCNEPVEGVAVFIEDISITLPEGESTSARDKLGRLTGEVIKTFQMAFKAGFMDWSPRMLLAMYTVEIQASTDVLGRVYDVLTRRRGQVIAESMNEGTPFFAIQATLPVAEAFGFADEIRKRTSGAAQPQLIFAGFEILDEDPFWVPFTEDDLEDLGELADKDNVAKKYMDGVRKRKGLLVEGRNVATDAEKQKTLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVI6</accession>
    <name>A0ABR3YVI6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_004851</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000147">
        <property type="protein sequence ID" value="KAL1891778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF21">
        <property type="entry name" value="REGULATORY PROTEIN LEU3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="87"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="34"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="686"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="126"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="689"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="749" mass="83894" checksum="E0909125A60BC20B" modified="2025-10-08" version="1">MEEPAIIKQQPLSPSSPYVASRGFNGVAFSSATIPNPNIASLSTHSTKRKRSTMTGMEHHSSPGSPGVIDDEHAENEKKRQPGVKRACNECRQQKLRCTVVQDPFQPCQRCTRLKLECKIESNFKRVGKRSKHAEMEKEIERLRRNIQRAKDAGYVFAEDDDSTTNHSPIAPYAHTRNTSMVSDGPLSSMLSLNNGQPQIQHAFPPAMKYAYELEDVKLTEDDTRSLFAEFFAFYHPFLPFLNHHQAPDQYYSQHPLLFWAIIAVASRRYGDGNDRTFLSPLAKPLTKLIWNTIGDVPSNYHVVKALCLLCTWPLPTSSSAVDPTHILCGVMMKIATMIGLHRPNHMQDFSRVSIDLDRDQLHDRVVTWAVCNIVAQTVGTGYGQPASTLYDWTLAVVDGEDSALKLPMELESRLMLERFCDKVSKEMYSNASDPRGVAGDGHRAMLLRVFRRDFNELKARLLSRNVSPIVKLHLSAANLHLRLAGFYDSSTTPGYLDDLMALYRSTEKFLKDVLETEKVTSPNDVIGGGILSYCTIYIQQMLVAASFTLLKLLKSFFVRVIDPKSGKQLFNGAVEAIRHTSVIPNDLQSRLAELMVQMWNGTPHAEHSSPDDDTPLPIDDSLQLKVRCRHSMSLVFDTIWRWREEFQDKGRGNLDIKHPTNVDTNEAMLSSLANGLGPHPAGLGFLNGSLTPTDQSSGLPSVGNNPSSIMSAMNYSEPLYDTFDPQNWMLDGLVDFQLNYSLTNMDGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVW8</accession>
    <name>A0ABR3YVW8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TauD/TfdA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_004721</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000140">
        <property type="protein sequence ID" value="KAL1892032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051323">
        <property type="entry name" value="AtsK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468:SF20">
        <property type="entry name" value="TAUD_TFDA-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="7">
        <location>
            <begin position="39"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1892032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="351" mass="38535" checksum="10A7FA3C13141383" modified="2025-10-08" version="1">MPALVDSTSSIIGGNPIARPSISTPLKNSGSLAGFSQGDLTPAIGTEFTGLQVSYLLEQDDNVIRDLAVTVSQRGVVFLRNQDVVPEQMKALMLRLTKAAGSPSSSTLHIHPLTEKGSELGDQISVISSEKQKKGGGLTHQLSDVSRFAANGWHSDITFEPAPSDYAMLKIHTLPATGGDTMWASAYDVYDRLSKPVQTLLESLTATHDATFFHDEARRLGNPLREGERGSPLNKGPALTAVHPIVRTNPVTGWKSIFVNRGFTKRINGISKDESDMLLQYLFNLITLNHDLQVRFKWNKNDLAIWDNRCTFHSATYDYSDIRTGDRVCSVGEAPYFDVNSISRGEAEMQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWQ3</accession>
    <name>A0ABR3YWQ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH-ubiquinone oxidoreductase 17.8 kDa subunit mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000126">
        <property type="protein sequence ID" value="KAL1892683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034444">
        <property type="entry name" value="Nuo17.8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42100">
        <property type="entry name" value="OXIDOREDUCTASE 178 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04320)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42100:SF1">
        <property type="entry name" value="OXIDOREDUCTASE 178 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04320)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="176" mass="19753" checksum="C301CF6C1539D6E7" modified="2025-10-08" version="1">MLAVRQRAVRLALRARPVRSQQRHSSSHGHEHAHHGHAAPVNESFGPGFYMLAAALPAGITLYQLSQPDAHGTQPAITRYLQQYMALGDLWEERNKGHVAAVEEAARDRLLFFHQPRPHHYEVREIESLFAGSQRCVPPSMNVNLDKVTQHYRNLHHEDEARKARALASKAAAGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX50</accession>
    <name>A0ABR3YX50_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein kinase activating protein dpb11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">DPB11</name>
        <name evidence="4" type="ORF">Cpir12675_004367</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000121">
        <property type="protein sequence ID" value="KAL1892833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18433">
        <property type="entry name" value="BRCT_Rad4_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17731">
        <property type="entry name" value="BRCT_TopBP1_rpt2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059215">
        <property type="entry name" value="BRCT2_TopBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13561">
        <property type="entry name" value="DNA REPLICATION REGULATOR DPB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13561:SF20">
        <property type="entry name" value="DNA TOPOISOMERASE 2-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12738">
        <property type="entry name" value="PTCB-BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BRCT" evidence="3">
        <location>
            <begin position="12"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="3">
        <location>
            <begin position="133"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="3">
        <location>
            <begin position="320"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="3">
        <location>
            <begin position="431"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="526"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="636"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="701"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="782"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="531"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="542"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="580"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="638"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="711"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="741"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="782"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="812"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="826"/>
            <end position="835"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="889" mass="95816" checksum="0919B8074F007D4F" modified="2025-10-08" version="1">MATADNDVNGSEPSNPLTGVTVCCTSLPVYERETVALAVQQLGGEHIYDLTPEVTHLLVGKYDTPKYRHVARARPDIKAMDPAWINAVRDAWRADEFDFAALEKQYQLLPLETNGVSTIKGDDASAVVKRGQLLVCLTGFDDPHERARIRQLIEKNGGIYSGELTKAATHLIVSKPTGRKYEAAINWGLYTVSVSWLAQSVERGMILDEKCFNPLLPLEQQGSGAYVPRVNTKRKRPATELQGAETKLRKLRKTASMKLGSEHASVWNSILGGMKPTNAAESTPKPVDSFADGPEFRPPPAVSPPTNLPPAILEPTPLSHDMSIFAGCNFYIYGFESKKLGVARQTVSSRGATICNSADEVEALPCSKKRFILVPQDSPWDKIKHLDGSSMVAVHIVTEFFIEKCLFRKALLDPTENVIGQPFKAFPIAEFGSLKINMSGFSGTDLHHISKTVDQLGGKVCEFFNAKSSILILRSLQGARKEKLESAILNNIPIVSADWLWACVSSGTKAPLNDFKFTELEQRAGLLQPRKSQDPLRKSRSETMPTSGNTRAKTILKSGDQDIAGTSGSRPNSRALPSRSFDNSAFTHSDNPQPTSLSKRTRSESTRHLSHIADGFAPCKSGVLFDVSVNALNKTAEKSTPAGSKKAAPPSASIQESPPRQVSKLAKEPSKASVSFLQAALDNESDDEEQQMGAPVDIAPTREQSAESAAKDGAGAGAPQAQDKPSPQSGVLPETDIPTPAAQNPLSAQPTVASVPASDTKAKERKALSAQLLNILDSHIATSNGSASASPHESSNDAAKKRNRRVFGRNLSTTSAASTISSNSHQEAEAEKDNDVPGASSRHSDTGRPPPATQVEYRDPEAVKVRAALLDKMSGRTTSESLRGRRSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX94</accession>
    <name>A0ABR3YX94_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phosphatidylinositol N-acetylglucosaminyltransferase</fullName>
            <ecNumber evidence="3">2.4.1.198</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GlcNAc-PI synthesis protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SPT14</name>
        <name evidence="12" type="ORF">Cpir12675_004432</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalytic subunit in the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.198" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000125">
        <property type="protein sequence ID" value="KAL1892700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017176">
        <property type="term" value="F:phosphatidylinositol N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03796">
        <property type="entry name" value="GT4_PIG-A-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039507">
        <property type="entry name" value="PIG-A/GPI3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013234">
        <property type="entry name" value="PIGA_GPI_anchor_biosynthesis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45871">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45871:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08288">
        <property type="entry name" value="PIGA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="419"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="PIGA GPI anchor biosynthesis" evidence="11">
        <location>
            <begin position="45"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="10">
        <location>
            <begin position="201"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="457"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="457"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1892700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="482" mass="54615" checksum="1CA9152AF5418A38" modified="2025-10-08" version="1">MPRRTYNIAMVSDFFYPQPGGVESHIYQLATKLVDRGHKVIIITHAYEDRKGVRYLTNGIKVYYCPFAVIFRQSTFPTVFSFFPLFRNIIIREQIEIVHGHASLSNLCHEAILHARTMGLRTVFTDHSLFGFADASSILANKLLKFTLSDVDHVICVSHTCKENTVLRASLDPLMVSVIPNAVVADNFHPREPPRPAPGPLDPITIVVISRLFYNKGTDLLTAAIPRILENYPNTRFIIAGDGPKAIDLQQMIEQNVLQDRVLMLGKVRHEEVRDVMVRGHIYLHPSLTEAFGTVIVEAASCGLYVVATQVGGIPEVLPSHMTVFAKPEEDDLVAATGRAIANLRAGKVHPELFHDEVRMMYSWVNVAKRAERVYDGISGNISELEFYGDDASVTPRRSRVQGFALIDRLKRYYGCGLWAGKLFCICAIVDYLLFMFLEWAFPRSRIDICDEWPRKRYDSDSESGYSERRGRDASHVRNRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXA9</accession>
    <name>A0ABR3YXA9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ceramide glucosyltransferase</fullName>
            <ecNumber evidence="5">2.4.1.80</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Glucosylceramide synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">UDP-glucose ceramide glucosyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">UDP-glucose:N-acylsphingosine D-glucosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">HSX11</name>
        <name evidence="17" type="ORF">Cpir12675_004485</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.80" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000128">
        <property type="protein sequence ID" value="KAL1892557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008120">
        <property type="term" value="F:ceramide glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025993">
        <property type="entry name" value="Ceramide_glucosylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12726">
        <property type="entry name" value="CERAMIDE GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12726:SF0">
        <property type="entry name" value="CERAMIDE GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13506">
        <property type="entry name" value="Glyco_transf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 17" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="416"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="524"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="529"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="545"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1892557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="560" mass="62255" checksum="350632C844B6CCD8" modified="2025-10-08" version="1">MAFSDLHILASACLGWSVGIFIVQFIGISRLFRNFSKVPRPPISPSLPSSQIPHVTIIRPVKGLEPGLYECIAATFKQDYPVNKLSIRLCISEKSDPAYPVLQRIINDFPEFDAQVLVEEEDPVLHGVNGHVNNLGPNPKIRNISRAYREAPSDIIWIADCNVWVGHGVAGRMVDKLVGFRAGGQRGPMYKFVHQLPLLVDIDRPKTAGTEPLLSVASSFTPAISGTPISTPRRKTQSLGNAFSSGGGLLDEMFMATSHAKFYSAINTVSVAPCIVGKSNMFRKSHLDMLTDPDQNPVLKEQDKNHPKGIDYFSIYICEDHLIGDLLWRSKIPGFRNHGMCLGDLAIQPTSSMPVSAFFARRSRWLRARKWTVPAATVVEPGVESLVCCGAFAYAATSLPWFANRLGIPPASTAQLIIWVLAVLLWMMFDYMTFCMLHRGSSIEADHDTPMWARGTEKNEGSTRRPFRQWALTWIGRELLALPIWTYAVLLGTTVNWRGRSFRVRMDMRVVELQKTDSHMICGGDGSQARYSPTHRGNGSGTRTPEIEMGRSGSDSRRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYY7</accession>
    <name>A0ABR3YYY7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000108">
        <property type="protein sequence ID" value="KAL1893463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="545" mass="56901" checksum="6B8D4A900B298D79" modified="2025-10-08" version="1">MAAGLLPKTQDASRSGGNVSRSNSSRALAARSTTVTTNTATTIATPTASTTDNILEFIEESLTTNTGLKKEPPHDEDLSGLEMELERELDLFSSEKKSRPKGVVVPHQTSMHKPGIETSPALAVAMTGAGKYHLRAQAQNSSDKDPVPPLPSSILALTAATPGKLSAETSTPSITAVCTAIPTPAPPPSPPLLSSLSRLPPEQLGLRSSLQLHQEGDGLVHTEQNVAASFEADLEAAHSSVPILDTESCASSTTSTLATKTAVIDNFPCPPAEKSTSTISGLEGDQASIEDEKIHKISSRTNDSELTLTLAVGSDLGLAASRYRNLSVVSTQTAITTASEAPDFDDSASLLTVGEPLEVFTAATAVRAAPARAEVINVRRPATAASSSSSGLQISVGGSDVGHRIITPSHGSETAAAPESTTISTHIPEATPPKIAMRRKQPHGLSLSNSHPPALLAHIISPGSLRSEPSPQNHHQHIRNHTIPTSILSPAMLDGLSPGSNYHTVPPAQLSAKEFGMLPPTIQRKVRTYLFLVLSIVSPIPSIAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYZ2</accession>
    <name>A0ABR3YYZ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin-conjugating enzyme E2 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">E2 ubiquitin-conjugating enzyme 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Ubiquitin carrier protein UBC2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Ubiquitin-protein ligase UBC2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">UBC2</name>
        <name evidence="10" type="ORF">Cpir12675_004316</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000119">
        <property type="protein sequence ID" value="KAL1892948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23790">
        <property type="entry name" value="UBCc_UBE2A_2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="9">
        <location>
            <begin position="4"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="7">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00039884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00041569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1892948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="151" mass="17229" checksum="3D040DE519CA7542" modified="2025-10-08" version="1">MSTTARRRLMRDFKRMQTDPPAGVSASPVPDNVMTWNAVIIGPVDTPFEDGTFRLVMQFEEQYPNKPPAVRFISEMFHPNVYATGELCLDILQNRWSPTYDVAAVLTSIQSLLNDPNTGSPANVEASNLYKDNRKEYTKRVRETVEKSWDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZJ4</accession>
    <name>A0ABR3YZJ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Gfd2/YDR514C-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003967</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000103">
        <property type="protein sequence ID" value="KAL1893811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040151">
        <property type="entry name" value="Gfd2/YDR514C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048519">
        <property type="entry name" value="Gfd2/YDR514C-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28083">
        <property type="entry name" value="GOOD FOR FULL DBP5 ACTIVITY PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28083:SF1">
        <property type="entry name" value="GOOD FOR FULL DBP5 ACTIVITY PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21762">
        <property type="entry name" value="DEDDh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfd2/YDR514C-like C-terminal" evidence="1">
        <location>
            <begin position="55"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="258" mass="29461" checksum="50121F946534D865" modified="2025-10-08" version="1">MGGNKRSREKRREEKHQQRQHMLQRLQDVLGLIHPEFQSFDSLPQINRPKEEYPVLVSIDFELWEVNGSTITEIGLAILDPLLLRGLAPGDRGANWWSLVYAKHIWIKECQHMVNREYVAGCPESFNFGKTDIIPQRIKLELTKSFLEEVLVPRRPLYVVGHDVGQDIQSFDNMGLMLESLTPELTLIDSREIYTLLANTFEGPSLGSALTGLNMDSCNLHNAGNDAVYTLRVCLALALVLKESDTQAYKTRELLDWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZQ5</accession>
    <name>A0ABR3YZQ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">6-phosphofructo-2-kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_004145</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000111">
        <property type="protein sequence ID" value="KAL1893407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003094">
        <property type="entry name" value="6Pfruct_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013079">
        <property type="entry name" value="6Phosfructo_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606">
        <property type="entry name" value="6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606:SF39">
        <property type="entry name" value="6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2,6-BISPHOSPHATASE YLR345W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01591">
        <property type="entry name" value="6PF2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000709">
        <property type="entry name" value="6PFK_2-Ptase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00991">
        <property type="entry name" value="6PFRUCTKNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphofructo-2-kinase" evidence="4">
        <location>
            <begin position="44"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="487"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="505"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="546" mass="61909" checksum="07F52AF6B17E0942" modified="2025-10-08" version="1">MDTLLTAEIALNAPRYRRRSSTFIDGIHDTSDDHSMAPAQLYSTMSGRLFHSGRIAIVMVGLPARGKTHICVSMSRYLQWLGVKTRIFHLGDYRRATVEGGNVPEDYFFPNASPASVILRQKILKKCREDIYNWLNHANGQVAIYDAVNPTRASRRALTKEFAKHDVQTLFIESFVDDDSILLENARNVKISSSDFEGMNPDEAAHLYLRRIEARIPGFETMDESELNFVRMINAGRKFFYNNVSFNYLSHRIVFYLTNLHIKSRATFFIRAGPTSEGESYLTDSALSEEGLDYSRKMTDEILKHRELDHAELLKTRPDATMRDLTVWTSTRMRTIQTADYLKQLGYKVRQRPQMSQINLGACENLSEAGIRNRYSDEAEKHEIDPYHHRYPRAESYHDLAVRLEPIILELEREQNDLLIIAHESVLRVLYAYLMHCSTRDIPTLNFPRNEIIEIIPAAYQNEARRLVIPGLSDNVMAGTRVASPVTYSTPASDSDVAPKENITEDASPNTSGASVPATPSASALHARLVGGVETPDLADSFRDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZR5</accession>
    <name>A0ABR3YZR5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Transport protein particle subunit trs120</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_004112</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000109">
        <property type="protein sequence ID" value="KAL1893459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058565">
        <property type="entry name" value="Ig_TRAPPC9_Trs120_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058567">
        <property type="entry name" value="Ig_TRAPPC9_Trs120_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058568">
        <property type="entry name" value="Ig_TRAPPC9_Trs120_4th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058564">
        <property type="entry name" value="TPR_TRAPPC9_Trs120"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013935">
        <property type="entry name" value="Trs120_TRAPPC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058563">
        <property type="entry name" value="Trs120_TRAPPC9_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21512">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21512:SF5">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26254">
        <property type="entry name" value="Ig_TRAPPC9-Trs120_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26280">
        <property type="entry name" value="Ig_TRAPPC9-Trs120_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26282">
        <property type="entry name" value="Ig_TRAPPC9-Trs120_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26283">
        <property type="entry name" value="Ig_TRAPPC9-Trs120_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26251">
        <property type="entry name" value="TPR_TRAPPC9-Trs120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08626">
        <property type="entry name" value="TRAPPC9-Trs120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trs120/TRAPPC9 N-terminal" evidence="4">
        <location>
            <begin position="7"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="Trs120/TRAPPC9 TPR region" evidence="5">
        <location>
            <begin position="431"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="domain" description="Trs120/TRAPPC9 first Ig-like" evidence="6">
        <location>
            <begin position="753"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="domain" description="Trs120/TRAPPC9 third Ig-like" evidence="7">
        <location>
            <begin position="1087"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="domain" description="Trs120/TRAPPC9 fourth Ig-like" evidence="8">
        <location>
            <begin position="1273"/>
            <end position="1430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="220"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="233"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF26251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF26254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF26282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF26283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1434" mass="158629" checksum="0AFCC09B19C8FECC" modified="2025-10-08" version="1">MNTVDSLLPFAPARVRALLLPLGPIRSERFALFAERLQAEGIVPLCDVAADPRPHRNMFTPMTYPNGSIFFEFVTYMPPASQLSLSPFDLYREPLVILAIADGAELTRSTYSTSASPANTATTLAEKNIRALDQELEGLRDQYHRALVHQVVLFEYDSNPDNIISIPEGIVTVPSTTTAGSITPKMVMCDLSSRLLAEMQTMAKSIEGVGYVDSPGQVSAARGRALPDEPRRNSQVSMPISRSSAGAEARNLSRMSMPPLKTSLSNISRSRPRRPSNPIAEHSAVEGQDSGRSTPEAFGPGFRTATPDGFRSPPPERISVQGFGSNGINEKLRQKGKSRVQIVIGSMYLQAGRWSNALKELSEGAATSRALNDHMWHGKALELILCCLFAMGWAELEFSIPQVCAAALDRPIPEAKPDPSFPDQPRHLRALQAILPDLLDRILSLYSRVSAEKLPQLPMSEAIIRFCKIMSAMQHTNGLLNKTCFDILVEGRWPEKQLTTSPRFTISPTRQTIVTLLFKAFPASSTELLTVVDRAAILSGICFVLGKIGYHRKKTMVSRELMSVLISGLVEARTRGAADVGIHPAAGLVSLTGPGAHTKGATLELQEEDVEQGISNLLDVMCRNYGVIDFEMPSKMGSPVQNNEEMDAIVSRIRRQSAARLYGFPGVKLNMLRACINFCEALPDFQGVLKYSSDLLRTAGSGVAPGPRGDDASPMIPREEQTRLLTNISKTYELSRRLGVTDLAGEYWDEFLVRGVSLEPLPEAKAPVQHTKSIIPGVTVSRTSQDVNPFIYNPFLKADEKEAQQSLIAMEPATFKVTLQNPYDIEVNIESISLVGEGIKFESDKEHVIIGSYRTHVARIVGIPQEGGTLRITGARIKVNGCRERVFPIIHDRWVPSPNVKIKAMGMQALQHAVENESLGSPPLKLTPLELHVINEQPLVVLKATTLPQSSIMILEGERKRFRVTLENTSKKTAVNFILFSFDDSTQAPLRAALQNRDSTPSEMYEYELILMKKQVLRIHKQPDEKRHIAPRGNVTYEFEILGKPGLTSASIQIDYAYLGDNTDDIGPKFHTRRISLPITVTVNGSVEISRCDVMTLFGPIPAPLWEHVHYNSADGTRPFLSSPLPPCDAVMAEGKTAPEDCCLLSLDLRNIWPSNIQVTIATKDGVCIDESVLPGNTTRVVLPIRRIHLENPHLAIPALNPNRNRQFVVSSSKVSPDFERNVREAFWYREHILDNIQATWRTTSGPKHSGAVELRSIRLTARMIEAIKVEDVSIDISLEDENGKSTGNLMAVDAFSQVRVRVTNRSPNPIFPLLRLVPALCHRPANMAMESTRKFAWNGVLQRRLPLLGANTSTEVVLGFTPLCRGKFEITVSVEEAMLFESESDKAERKMKEQGRQRADTEALMEAAVALGIKERRIWHTRQPCVFTVVDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0F7</accession>
    <name>A0ABR3Z0F7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ZZ-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_003802</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000096">
        <property type="protein sequence ID" value="KAL1894114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14947">
        <property type="entry name" value="NBR1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02249">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032350">
        <property type="entry name" value="Nbr1_FW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20930">
        <property type="entry name" value="OVARIAN CARCINOMA ANTIGEN CA125-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20930:SF0">
        <property type="entry name" value="PROTEIN ILRUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16158">
        <property type="entry name" value="N_BRCA1_IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00569">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ZZ-type" evidence="6">
        <location>
            <begin position="322"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="134"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="202"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="420"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="138"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="165"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="202"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="426"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1894114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1012" mass="110864" checksum="65F1C1E7D6EFACB6" modified="2025-10-08" version="1">MSSAPSQQQPPLQSEQPSVPAANVNVKIIINNHVHRKVLTLDAMHVDLFERSIRKCVPHHMGDILIERYSDSAGRYTIVDPAIPSSYKQLYRAAKAKGKLRVRIIQVPQPGQASDVGTALTSATSILSLAPIDQANDSNKNTTGTGTNTTTSNTNIQKPEIHPITKAKPHSQTHTPIRKRSKATVRLPPPTRAQLEVISSHNVTASSENDQSLLNSNQHTPNQQNHVSGHENTLKWFGNYKRGYPIFSVTEQLQGPGQVNSTTFDTTSSNINVNSDVTTAPIVGSTHECAPTTTEFPVSNIKLASTLSTACPAVIYPPKGPDFQICCNSCSNAIDSDHWHCNKCDMGDYDLCPSCFAEGKGCDDDGHWLIRRAVVDGVLVSGSTEVARVSKLASSKSEKNMNDKMSSLSFNEHETKLMEQSPIVIKRKDNPENQETKTEDRETSNGNNDKLSIGHVIEPSPKENLRSSYNSPWNVEAHEDKAPAISRRTCNGCVHEFADNYFVHCTHCPDFDLCFNCFTPTHGHHPAHGFVLVAKGPHVPQTVLAWLKGHHNRHHALCDGCDKAILGTRYKCLDCPDWDYCSSCSSTISITHKGHRFVRLYEPMSTLVSQRPPAAQHYGVYCDGPLCVAKGHKNHISGVRYKCGFCHDLDFCDACEASPSNTHDKTHPLIMMKTPTSHLVVSSRLYDGNCRLMDCMGDIVDEAGLDKNNLPSLSMATKPAVADVEPVKETPSTTTMPAAAILGGVRPAPLSVETLSPPMPSPIPPTEVKTAFPSYTEAPSRSQWPSMALVEQTPDKMICVPTDYVFTMCWELKNNGETVWPAGSYIELNGGDQLFTPKMRREMAQETSSRSVFRVTASDLYLEPVAPGESAKYEVSLCSPMEPGTYSSGWRLTMSGGHRVGELMISEIRVEGPIPVLAMSNKAGTEVKAEKTSVDHTMVFPTLETESLVATLTGHTDDISPATTSATVTTDSEIGSLGDFEPNEEWVSSDAEFMTDEEYDILDGLEDECRSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z207</accession>
    <name>A0ABR3Z207_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Dipeptidyl peptidase 3</fullName>
            <ecNumber evidence="11">3.4.14.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Dipeptidyl aminopeptidase III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Dipeptidyl peptidase III</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_003570</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Release of an N-terminal dipeptide from a peptide comprising four or more residues, with broad specificity. Also acts on dipeptidyl 2-naphthylamides.</text>
            <dbReference type="EC" id="3.4.14.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the peptidase M49 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.14.4" evidence="11"/>
    <dbReference type="EMBL" id="JAWDJO010000087">
        <property type="protein sequence ID" value="KAL1894631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.30">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005317">
        <property type="entry name" value="Dipeptidyl-peptase3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039461">
        <property type="entry name" value="Peptidase_M49"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23422:SF11">
        <property type="entry name" value="DIPEPTIDYL PEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23422">
        <property type="entry name" value="DIPEPTIDYL PEPTIDASE III-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03571">
        <property type="entry name" value="Peptidase_M49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007828">
        <property type="entry name" value="Dipeptidyl-peptidase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 11" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR007828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1894631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="706" mass="78321" checksum="5C1A6DA485C4E0D6" modified="2025-10-08" version="1">MSTDDLKHFLADAPPSVVRLEIEKHFNALDEKLKRYAHYISKSSFAGTRIVLRQISPESEPIYDFIISLHKACNGNWKALAANVGITETDLNAFLQYAGMFLGNNGNYKSFGDSKFIPRCNESVFAALASASPEAGKFYKATNGAIFSSDKPGLLHLGYTDAGHLTTYYPNSPSITKDEIDAVSSWMEKKGLLPENTRLVKTPQDVFNILIASANKDVPTTGGDIGKETSFTVEGGLLDGKTINLVYGDYAAEMKMAADYMFKAYENAANENQLKMTEAYSKSFGNGSLLDFKDSQRFWIRDKQPMVECNIGFIETYRDPAGVRGEWEGFVSMVNLERTRAFGELVASAPKLIPLLPWGAEFEKDKFLSPDFTSLEVLTFAGSGIPAGINIPNYDDIRQTEGFKNVSLGNVLSAKSSNEAIPFIAESDLELYRKHRDSSFEVQVGLHELTGHGCGKLLQETSPGVFNFDKENPPTSPITNSPIKTWYKVGQTWGSVFGSIAASYEECRAELVAMYLCCEFPVLKIFGFGDGSIDMDSEAGDILYAAYLSMARAGLVSLEMWDPKSKKWGQAHSQARFSILQCFLEAGDDFCKLEYTKPDLSDMTIKLDRSKILTSGREAVGKYLQKLHIYKSTADVVEGSKFYNLMTHVDSDFWGGKVRSVVMNNKQPRKVFVQANTSIDTEGKVSLKHYDATLEGLIQSWVDRDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2P2</accession>
    <name>A0ABR3Z2P2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">WD repeat protein Lub1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">lub1</name>
        <name evidence="9" type="ORF">Cpir12675_003653</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000090">
        <property type="protein sequence ID" value="KAL1894476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.870">
        <property type="entry name" value="PFU (PLAA family ubiquitin binding), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015155">
        <property type="entry name" value="PFU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038122">
        <property type="entry name" value="PFU_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013535">
        <property type="entry name" value="PUL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849">
        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849:SF0">
        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09070">
        <property type="entry name" value="PFU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08324">
        <property type="entry name" value="PUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51394">
        <property type="entry name" value="PFU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51396">
        <property type="entry name" value="PUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="9"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="102"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="234"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="PFU" evidence="7">
        <location>
            <begin position="373"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="PUL" evidence="8">
        <location>
            <begin position="497"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="463"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="767" mass="84076" checksum="E07CD40A3A845191" modified="2025-10-08" version="1">MAFQLSAQLIGHESDVRDAIFPSSSLILTASRDGTVRRWQRTSDSAFEAFLVSQGSEYINSVAYIPPSIRYPNGLAISGGKDTIIDVRSPKATPENNAERMLIGHGHNICTLDVSPKGTYVISGGWDCQARVWNVEKWETEFMLQEHELSVWAVLAYDENTVITGCADKKIRIFDLRNSVAGDVRPASTIHTPDIVRALCRLPSGHPTGAEIACACSDGVIRLYKLDGTMVSELIGHDSYIYSLAILPSGEIVSSGEDRTVKIWNGSSCIQTITHPAISVWSVAACAETGDIVTAASDNVARIFTRSPERLADAETLREFKEAVSNSSIPQKPMGGINKEKLPGTEFLTTKMGKKDGQVQVIKHDDGSLAAYTWSMILQKWEHVGAVVDSAGSSGRKQEYNGQQYDFVFDVDIDDSKPPLKLPFNLSQNLFEAARKFLEDNELPITYLDNVVKFLETNTQGATIGEAADPASSRPDPMGSDARYHPGDENQPSPAKKTLPQTDYIALLNGKFDNTFNKIHTVNKNLISAGNKEFALNPAEEQVLSELRPCIEGNTPIQATSLEIVIKVASRWNYPDVLPGLDLLRYLVRYPGTALYRDSETGNIIDLVISSSLNVPSGQEINVNCIVMAIRCLSNLFMSTEGVSLMTDQFTKALEFLEKVAGISGTAIGASNRHVQIASTTTLINLAVLGAKTEVSLDVRRRMANILGIILKDNTDSEVLYRGLVALGTMASHKTDITQDWRPWVKSVVERCDETRVKILGRECLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2Y4</accession>
    <name>A0ABR3Z2Y4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003574</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000087">
        <property type="protein sequence ID" value="KAL1894635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05154">
        <property type="entry name" value="ACAD10_11_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052898">
        <property type="entry name" value="ACAD10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041726">
        <property type="entry name" value="ACAD10_11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47829:SF1">
        <property type="entry name" value="HAD FAMILY PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47829">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="30"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="403" mass="43763" checksum="4C00218BCEB3BA7C" modified="2025-10-08" version="1">MAGTVRQPIDKAALACYLSTAAPTISQPFTIKQFGLGQSNPTYQLTSLPTAPGGKPQHHVLRKKPPGALVSKTAHKVEREYRVLSALSNASRSESSRESSAPGVPVPKTVCLCEDSSVIGTPFYVMEFVEGRIFEDFLMPGVVATDRAAMWRQAVTVLSALHAVDYKGIGLETFGRPNGFFQRQVATWKAICEAQQKVRDVETGEPVGRLPYMDELLKYFGDPKNQPRDRAGLVHGDFKIDNMVFALQGTEVVGLLDWEMSTIGHPLSDLCNFLTKFILARQSEVAASSGITITKVASPPGNPLAVSDPAFLPGRTPGLPSLDEIVSWYAASSGYDPRIGNELVYGMAFTIFRLAAICHGIAARYALRQASSAMARQNGLQMVPLAEYAWALVLATKKLTMKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2Z1</accession>
    <name>A0ABR3Z2Z1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome c oxidase assembly protein cox18, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">COX18</name>
        <name evidence="6" type="ORF">Cpir12675_003414</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OXA1/ALB3/YidC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000080">
        <property type="protein sequence ID" value="KAL1894999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428:SF65">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX18, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="OXA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1894999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="338" mass="37235" checksum="F67E783CAD3DE50E" modified="2025-10-08" version="1">MNTLRLQRLSRTARANGLPCTNQASILCPKYRLPSIAYSGLRVAGSRSFLFDPIFLPVQEAVISFHNVTGISWYLLIPASGVVHTLLFRMPSFLLARRDRDKVMHGMLMSHAIQAATARAYGNSSIKNILAPRLTSRAYQALGKTPADMEPAKKLSSKALIGVSFLSWFYSVSLFRRLTGGLSITGEQLSKPDPSVFTEGCLWFQDLTASDPTYILPLTSMGLIIWSWIPKTEAGWRDVLGKPDPLKPSGMSPLRLRATRVSLIATPLFIAGLDSLTAGSSLFVVSSLLSFRAFKLLDKKDPLTDMRFDKLADAIVNSRTSVPQGNGRPISWFIKNAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z311</accession>
    <name>A0ABR3Z311_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003537</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000086">
        <property type="protein sequence ID" value="KAL1894647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="entry name" value="HPT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018810">
        <property type="entry name" value="UPF0662"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28086:SF1">
        <property type="entry name" value="CU(2+) SUPPRESSING AND BLEOMYCIN SENSITIVE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28086">
        <property type="entry name" value="UPF0662 PROTEIN YPL260W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10303">
        <property type="entry name" value="DUF2408"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="480"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="494" mass="56311" checksum="8765A22F89C704EB" modified="2025-10-08" version="1">MDTPSCPQPADSQEQQILTHLETIRDKLILLKRDRTNYIRSQDVLPLYDEVIEQVRLLNAARVGKEATYENRVDRVLESCFQLISLFFMTIGRNYEAPAAYALTSTIKRLADHLTESTLFSQKDLDSITHTLEKLTQYIENGRDSHDPIVLDLLLKRTGFCKEMLKSLQAKQEPLGEPLPAIHEKLISILRSISLANTRSKFSNSEVHKLALQLAEIDALRKEGNFLAPDGSVAEGSDKISLLLFKCMKWAEIVQVKKGAIPAAFKPMYNDLVRVRSELDKISMTQAWSLREADLYDFQRLLDRYDEARVDGNWLDNEGKPAELYVQRTLLYLVRRCYAYIYSLMISSEPVSEGLLPIYNQLQTLKRCLIEVKKNGGIGSPRELYPYSMKLNSIDNQRVDGKFLVNGDIPEGQGSVNELLAECFDLVYELRIEAQNAVDEKAEAEEEARETARAEQEEEEEREEAAKLRAEKAAAALVQAERKEREEEEAKSQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3W9</accession>
    <name>A0ABR3Z3W9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Chromatin modification-related protein EAF7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_003285</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EAF7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000075">
        <property type="protein sequence ID" value="KAL1895328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012423">
        <property type="entry name" value="Eaf7/MRGBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13581">
        <property type="entry name" value="MRG-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13581:SF5">
        <property type="entry name" value="MRG_MORF4L-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07904">
        <property type="entry name" value="Eaf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="159"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="28"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="194"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="264"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="293"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1895328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="334" mass="36776" checksum="BCAFE3280153B461" modified="2025-10-08" version="1">MPPRKKPKASQPSAAPEIDDDAMDIDQASLSPSPASPLIGSPLSINQPGLEDLTSYWTADQEASLFKATIRWKPAGMHRRFRMLSIHEHLRNHGFDPEIYPHIRIPHIWQKLRVFYNLDAIDERENFEDDSPEDRYHEFQLPIGMFYGRIMERVLDTDRDTSPECLNGSPSPSPPPDSPDSEAHSPAPPPPQPTTAVSTPTPTTATSKRKQRRSDAAHLAKATTRSSTIGDSEDLSDAPPRTTPKAGARGRAAAAAATAASTRPRTRTRGNARRRTAESEDPPSENESKAGEADSDDSDDPEEPQSSEEEPKTKPKTTRGRSAGTVRARGKKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3Z7</accession>
    <name>A0ABR3Z3Z7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cell division cycle protein 123</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDC123 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000081">
        <property type="protein sequence ID" value="KAL1894971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009772">
        <property type="entry name" value="CDC123"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15323:SF6">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 123 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15323">
        <property type="entry name" value="D123 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07065">
        <property type="entry name" value="D123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="432" mass="49144" checksum="C8E006084C44AB41" modified="2025-10-08" version="1">MPEATGSTAPLGETKFPLIKKSHMVNCAYDQWFPRYRTSCIKSRIIPLTEEMVSYFKEDGILLADDDEQGEEETADEEWHSTGPVSSGVVRKVYSDDESEEEEERTPPNVRFPVQHKFIKDAIQELGGSVVPKLNWSTPKDAAWISRHQNTLKCTSPNDIYLLLKSSSFVTHDLEYAFQETIDDYHPTSHDTNRFKYALVLRPFFNMHPALEFRCFVKQRNLIAICQRDLNYYDFLFKLKNDIIDRVDDFFESKLRMTFPDDSFVFDVYIPEDNDTTDGTGLGRLRLIDINPWASTTDSILFDWKELLNKIVPQPLIGPPPVASFSSSAEKGEQECFVRLKLDGAAVVDISESIDSSTDDDDYLEPDLRLVNKEDPSAYNFSSTQYSAHKLPKEVVDAGLGGQGGMREFARQWKEATEGRGGEMFQSPTGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4G2</accession>
    <name>A0ABR3Z4G2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000072">
        <property type="protein sequence ID" value="KAL1895521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="393" mass="42331" checksum="CF72543641671037" modified="2025-10-08" version="1">MEYPTLNVARRHPSSSQRRSPVINSSIAKRQSSHNTSPHAKRWSMYDGNIFAAAANAMNYSLDSSMPRVRPSSMLMAATPVSSMSTSAASYMAVLSAPSTATVVTSPLSEPISDNMIFSPGLAMSQQQQQQQQQQDFYSPASYTYMTAPQYARTCNLSHQQQQQQQCSSNYSDYPPTLPDSVPSSFDISAMSMPGFEAPSSATRSPQFTAPLTPDHMLAPANTMCVGLASANGMAPFSIPSAVAVSTSPSAVVDADEDSGEILQGMGLYDDDALVKDGVDLALDSSRDCMQSLLADTTRAAQPTKMLLMKDFEPEATDDEDETEAEAEQTGADDNEDTDAAADTAAALPVVQEQQSQIQSLAQPYFQPTAVYAERIYPVQPLYTQQPVSSSWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4M8</accession>
    <name>A0ABR3Z4M8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Stc1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000080">
        <property type="protein sequence ID" value="KAL1895005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="240" mass="26803" checksum="119AEED6C746B946" modified="2025-10-08" version="1">MPSHYKAPPSSFRQYICAQCGNWCKIDEFSVVEINKLIKRQRSEKVTAEKSGLICSECSIWNGMVNRGTAIAAPGHQVSVDEVQETHYKDPALAYPMVRTELDLKRRIQGFAARRELPVPCIRGPGRYYVPSTTQERLDQGFDADAAKHPEMVRHQYKGFVPPAAFQKEYEAMMSEETGNAQDGAAEGQSSSAKNSDSSTGKGKASLQAPVHIESKHSKKSQEIYIQEYGRWVDKKMSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4V8</accession>
    <name>A0ABR3Z4V8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Arylsulfatase</fullName>
            <shortName evidence="5">AS</shortName>
            <ecNumber evidence="5">3.1.6.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Aryl-sulfate sulphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_003262</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>an aryl sulfate + H2O = a phenol + sulfate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17261"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
            <dbReference type="ChEBI" id="CHEBI:33853"/>
            <dbReference type="ChEBI" id="CHEBI:140317"/>
            <dbReference type="EC" id="3.1.6.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the sulfatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000074">
        <property type="protein sequence ID" value="KAL1895355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16147">
        <property type="entry name" value="G6S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012083">
        <property type="entry name" value="Arylsulfatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43108">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43108:SF8">
        <property type="entry name" value="SD21168P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000972">
        <property type="entry name" value="Arylsulf_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045949441" description="Arylsulfatase" evidence="6">
        <location>
            <begin position="24"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase N-terminal" evidence="7">
        <location>
            <begin position="44"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="595" mass="66690" checksum="1B72024ADB2CDE71" modified="2025-10-08" version="1">MQLSGPVSVVLAIVGSLIQCASTLETQQAPLLPSPDPRRVGRQPNIVFILIDDQDKRLDSLAYMPCVKKHLLEQGTSFENHFCTTAICCPSRVSLWTGKLAHNTNVTDVSPPYGGYPKFVSQGFNNAYLPVWLQNSGYNTYYTGKLFNSHNINNYDSPYPAGWNGSDFLLDPFTYQYLNSTYLHNRDAPQSYYGRHTTEILTEKAYNLLDEASQETRPFFLSIAPIAPHSNVGFTFHPDGTHTAHFTEPIPANRHKNLFGDAFVPRTPNFNPNKPTGASWIQLQDKLNGSAIEYNDHFYRQRLRALQGVDELVDGLFERLAEKGLLDNTYFFYTSDNGFHIGQHRLPPGKECGYEEDINVPLIIRGPGVPINKTTNLATTHIDLAPTLLHLAQSAFDSTFGFDGIPIPLTLSQLETAQNTRHDHVTVEFWGTGLAEGRHGFSNGAYVAENNTYKALRIVSASGQDYNLYYAVWCDGSRELYDLTTDPYQIVNLLHSSTSSAKPTLFSVPIQKLVERLDALLLVLKSCQGRTCVKPWQSLHPEGNVQKLGDALSPRFDHFYAEQVRVKYDHCESGYILSAEGPQFGRDGAAWHEWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z567</accession>
    <name>A0ABR3Z567_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000073">
        <property type="protein sequence ID" value="KAL1895379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="113" mass="11076" checksum="C6FD4EF6426519D9" modified="2025-10-08" version="1">MEDNSQILSLPNSTATIEVPAQNGEPASQTDAVSTSAAATTTTTATTAPAVASPIATAATSSMHNLPSISALATSQVQQGSQSSQVRTTMPPSQPMFMGASPAATAGGAGNTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z666</accession>
    <name>A0ABR3Z666_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Small ribosomal subunit protein uS7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_003087</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000068">
        <property type="protein sequence ID" value="KAL1895754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14868">
        <property type="entry name" value="uS7_Mitochondria_Fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="entry name" value="Ribosomal protein S7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_uS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_uS7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_uS7_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047988">
        <property type="entry name" value="Ribosomal_uS7m_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="RIBOSOMAL PROTEIN S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="Ribosomal protein S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS7" evidence="5">
        <location>
            <begin position="201"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1895754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="384" mass="41364" checksum="5080BE6E6DCD6DCA" modified="2025-10-08" version="1">MSSTRSIWGVACRSLAIRSRPVTGNKCVSSDAAMIRLAVQRRFASDSTNLPGSQQPVDPRTGKSSADRRLETMNQGSLKKRGEPAPAAAAGDMSREQMQALFDDVMAKSALSAIPNSMGTAAGGEAADSIASPGFVQVPGGLTEEQANVLYHEGRIPLATTANEALNALQSVAAGEAKVDHKTGAVKPDHKFPLPELPLPPNSRLQERYHPVLHQFVRLLMRDGKLSRAQRQLATVLNILRTSPPPILSPRYPLIPGAPPPAHLPLNPVLYLTVAIDSVSPLIKIRHLAGAAGGGQALDIPFPMEVRQRRRTAFQWIIDVVNKKPSRGSGRNDFPTRLAEEIVAVVEGKSSVWEKRQQVHKSGTVARANLNTFHGGKKGHRIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6U5</accession>
    <name>A0ABR3Z6U5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hsp70 ATPase ssc1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SSC1</name>
        <name evidence="5" type="ORF">Cpir12675_003022</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000065">
        <property type="protein sequence ID" value="KAL1895982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11733">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00332">
        <property type="entry name" value="DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012725">
        <property type="entry name" value="Chaperone_DnaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003520">
        <property type="entry name" value="PRK05183.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02350">
        <property type="entry name" value="prok_dnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="556"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="638"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="556"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="651"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="671" mass="72788" checksum="20D4E86C3101A558" modified="2025-10-08" version="1">MFASRLSRALPRATPMARVGRVGRSPLASQFARYESTDGKVTGTVIGIDLGTTNSAVAVMEGKTPKIIENSEGARTTPSVVGFSQDGERLVGVAAKRQAVVNPENTLFATKRLIGRKFTDNEVQRDIKEVPYKIVQHSNGDAWVSARDQKYSPSQIGGFVLNKMKETAEAYLSKPIKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVVNEPTAAALAYGLDKEADRVVAVYDLGGGTFDISVLEIQSGVFEVKSTNGDTHLGGEDFDITLVRHLVQQFKKESNIDLSSDRMAIQRIREAAEKAKIELSSSLQTDINLPFITADASGPKHINLKMTRAQLEKLVDPLIQRTIEPVRKALKDSTLQAKDIQEVILVGGMTRMPKVAESVKSIFGRDPAKSVNPDEAVAIGAAIQGAVLSGEVKDLLLLDVTPLSLGIETLGGVFTRLINRNTTIPTKKSQVFSTAADFQTAVEIKVFQGERELVKDNKLLGNFQLVGIPPAHRGVPQVEVTFDIDADSIVHVHAKDKSTNKDQSITIASGSGLSDSEIERMVEDSEKYAEQDKERKSSIEAANRADGMLNDTEKALNDHADKLDKAEADGIREKIASLREFISKSQAGEGTATAEEIKEKTDALQAASLNLFDKMHKARTSSEQAPPTEEQNNSSEGEKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7L8</accession>
    <name>A0ABR3Z7L8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Farnesyl pyrophosphate synthetase</fullName>
            <ecNumber evidence="6">2.5.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ERG20</name>
        <name evidence="6" type="ORF">Cpir12675_002752</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.1" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000056">
        <property type="protein sequence ID" value="KAL1896656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004161">
        <property type="term" value="F:dimethylallyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039702">
        <property type="entry name" value="FPS1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11525:SF0">
        <property type="entry name" value="FARNESYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11525">
        <property type="entry name" value="FARNESYL-PYROPHOSPHATE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01017">
        <property type="entry name" value="Polyprenyl_Transferase_Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1896656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="347" mass="40078" checksum="8891EE0B61EF57A0" modified="2025-10-08" version="1">MAQKITREQFEADFPKLVDCIMEHCDQFKLPDEFKEWFRRNLNANATGGKYNRGMTVHDSAMLLLEAPLSDEQRFQANCLGWMTELLQAFFLVSDDIMDASITRRGAPCWYLQENVGMVAINDAFMLESCIYILLKKFFRSHPCYLDLIELFHDITLKTELGQLCDLLTAPEEKIDLSKFSLDKHSFIVIYKTSWYSFYLPVALALHQLNIATPKNLKQAEDILLPLGELFQIQDDYLDNFGDPEHIGKIGTDIQDNKCSWLINTALAKATPEQRALLDENYGRKDPAREAVVKQLYNEMGLKKIFEDFEEERAAAIRAKIENLDESEGLKKSIMTAFLKKIYKRTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7M3</accession>
    <name>A0ABR3Z7M3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_002873</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000061">
        <property type="protein sequence ID" value="KAL1896227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF153">
        <property type="entry name" value="SUPEROXIDE-GENERATING NADPH OXIDASE HEAVY CHAIN SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01169">
        <property type="entry name" value="NADPH_oxidase_subgroup_(NOX)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="169"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="305"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="406"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="9">
        <location>
            <begin position="274"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1896227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="568" mass="64853" checksum="1DCAD26454050F4B" modified="2025-10-08" version="1">MDSSYEKPMERSRGTPLTRMLLSGEMTQERQSELTSKERFDRWMINEGYRRFFVFVFAVLQVLVFSFAAVNFSRKENLVTARNTFGFTFVIARSAALVLHVNIALILFPVCRTLISLARQTPLNGIIQFDKNITFHIVTAWSIVFWSWVHTVAHWNNFAQISAKNNLGFYGFLVANLVSGPGWTGYVMLVALMGMVMTSMEKPRRANYERFWYTHHMFIVFFFFWSIHGAFCMIQPDFAPFCSSVGPSAIGVFWQYWMYGGFVYLAERIAREVRGRHRTVISKVVQHPSNVCEIQIKKANTKTRAGQYIFLCCPAVSLWQYHPFTLTSAPEEDYISIHMRIVGDFTRELATVLGCDLGGGKDKVKGSNVVGTDANGIDPALRRVLPRVYVDGPFGSASEDVFKYEISMLVGAGIGVTPFASILKSIWYRMNYPKERTRLSKVYFFWICRDFGSFEWFRSLLLAIEAQDIDQRIEIHTYLTARIKADDAANIMINDANAEKDAITGLRSPTNFGRPNWDMIFRGVRKLHTPAECGVFFCGPKGLGSALHIFCNKYSDPGFSFVWGKENF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8E1</accession>
    <name>A0ABR3Z8E1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nucleolar pre-ribosomal-associated protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_002581</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000052">
        <property type="protein sequence ID" value="KAL1896933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059018">
        <property type="entry name" value="HEAT_URB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039844">
        <property type="entry name" value="URB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032436">
        <property type="entry name" value="URB1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021714">
        <property type="entry name" value="URB1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13500:SF0">
        <property type="entry name" value="NUCLEOLAR PRE-RIBOSOMAL-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13500">
        <property type="entry name" value="NUCLEOLAR PRERIBOSOMAL-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26140">
        <property type="entry name" value="HEAT_URB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16201">
        <property type="entry name" value="NopRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11707">
        <property type="entry name" value="Npa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="URB1 N-terminal" evidence="2">
        <location>
            <begin position="109"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="URB1 central HEAT repeat" evidence="4">
        <location>
            <begin position="638"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="domain" description="URB1 C-terminal" evidence="3">
        <location>
            <begin position="888"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="817"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF26140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1896933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1125" mass="125659" checksum="CCB8C6E43349040B" modified="2025-10-08" version="1">MGKRQPRDREVDTLFQDGPMSIHKKQKVAHEVPSSEPITSSRQMRMLLNFDPDARKTRHGLQSFKLFLDNLNLAADGDADVPKNREMLALYLESTQPPPDDDNAVYMQGLFETWANAVQTHNDGLLSSVAVVLSLLLQVISSDLDLVRHGMGICEALLQDRHLKLIARNLSSDPSKGFVISPTLRLLREVVSLDGGVFARRVFRCRQYTLAEFVRNLEVKHNTEGVEDATKASVRTNAIRLLTTFLKYLPADDRRELILTRGLMSHLTFLLKDDSPYVLSDLIESFTKYFLTDSKIPSYSKSLAFSAKILARFLNLYHYSHDANEPATIADKIHSFLMLACTAKDTGIMLSSSGFYPKGLDPTAVNSTRDCSGIMGVESLSWMDRYKTESPVVNTSLLEFILKLRPWANLKHSELLVGCFSACPELVAAYFQKQIAFTFDPKLSMTWIGYAAFLFNTIQLPIPEDFGSSARFSANIPPPSSIVLDSILPPALNQKVLTRCLGPQSPLVSFFATRLLVVAMQKLEEALKLHKEASESPIWRYAQRKLLDDFCHRIPDMKEVIRSYKAIPIDSVLHRATASHLLSLYYKQTPQIALAANFDASPLLISTLNHLETQFENAKDKAVLLIELENLLEIANYSPGMRWFAKTEGLSMSPFTALLQLACNTSHAFHSSRLEDAIALIASEHQVVSKSSGLKPFIEAVRQSEDISEEGWLVLDNCIQRAAASPLKYIDLLQEFSGDNSGSEPSRLSLVLVTLSEQVPHVCKTVNDGVLASLADLISKYASLLILYGESVYPITAVCVKMKEHLPWLQLPKAPKGAEAKQPGPFESKLADVGPSKANNPPRPDYATALEAICADMADADLDNSALTRWAIKNAEDLIDDGHAISVFKLLQSEHTSIRCEALVNLRKMAVKVRGSSHPEKEQVWLLISELVESCHNTVASSPAPSQFVAFASHSLSIISNPLHALYPKINRFLTKGPIWTPTKLPLIHDILHGEPSEDDKLYIELSWLFSYLLDCLQTKEDLAVFYRNNWMEKILCAGCNPNFRATLRGKVHKIIYKFTCMEGGSTMLVTRFGIVSWLKTQKAQATQPSEASVYQALTQRIWETCDKKHVEEWSGEGMSWAVEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8E6</accession>
    <name>A0ABR3Z8E6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="8">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">YUH1</name>
        <name evidence="10" type="ORF">Cpir12675_002574</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the peptidase C12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000052">
        <property type="protein sequence ID" value="KAL1896926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd09616">
        <property type="entry name" value="Peptidase_C12_UCH_L1_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.532.10">
        <property type="entry name" value="Peptidase C12, ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001578">
        <property type="entry name" value="Peptidase_C12_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036959">
        <property type="entry name" value="Peptidase_C12_UCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057254">
        <property type="entry name" value="UCH_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589:SF17">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01088">
        <property type="entry name" value="Peptidase_C12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00707">
        <property type="entry name" value="UBCTHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00140">
        <property type="entry name" value="UCH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52048">
        <property type="entry name" value="UCH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7 8" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4 7 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UCH catalytic" evidence="9">
        <location>
            <begin position="10"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="site" description="Important for enzyme activity" evidence="7">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1896926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="239" mass="26186" checksum="F1AFB4EF02AD7A31" modified="2025-10-08" version="1">MATATPNAISFVPLEANPELLTAMLHHLGMQKSLAVHDVWSLTDDEMLNFVPRPALALLLVFPVSATYEQHRQAEDANKDLYNESGDDQVLWFPQTIRNSCGLMGLLHAVSNGPARSLINPDSILDNILKQAIPLQARERASILETSKDLAVIHARAADKGATAAPEASEDVDLHYVCFVKGNDGTLWELDGRRKGPLERGHLSSDEDVLSRAALENGPLKFLQAESKDLRFSCVILAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8F2</accession>
    <name>A0ABR3Z8F2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 8</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_002766</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000057">
        <property type="protein sequence ID" value="KAL1896477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007255">
        <property type="entry name" value="COG8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21311">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21311:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04124">
        <property type="entry name" value="Dor1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1896477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="445" mass="48414" checksum="66A2C2630CA7D69A" modified="2025-10-08" version="1">MASSLYDILGLGNSPDDHVRHEYLSYLTGLGVDELQHVEPERLSQASHTSLLAIQNLSKRSHKAIIASANHHATLSTSLPALGASAAQLKACIPQLDSQASRFSEIYSKSSDNETLKKRRESLLLLRNIDRILDLMELPTLISAAASATPANHAAALDLSAHIRRIHMLYPNSSLVCSISRQAEEAVEGIATSLISSLKTPTLKLAASLRAVGSLRRVLADLPGVTRLLGRSAPSPVRYGMNEQTLETLFILCRLDTLITTLHALSPLQKLADDEKARQSSKTASSTWSSGQQTERFLKRYIEIFREQSFGIVSMYKSLFTGSDLTMSRDAETLDPLQPSPAPLSTFALHLVEILLDTLHKYLPVVSDRASRDSILTQVLYCAGSLGRLGIEFSILLAELDEAEWIDVVKRHRLLAGRLESILGDFKAGAGAAGGPSSRKVSMSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAC7</accession>
    <name>A0ABR3ZAC7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chromosome loss-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">CHL4</name>
        <name evidence="2" type="ORF">Cpir12675_002286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000043">
        <property type="protein sequence ID" value="KAL1897558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.720">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007902">
        <property type="entry name" value="Chl4/mis15/CENP-N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05238">
        <property type="entry name" value="CENP-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="368"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="390" mass="43367" checksum="BD208540E68E91A8" modified="2025-10-08" version="1">MDTIEELQDLYSSMQERKGSKREVVDRMLEGDWREGVTMYQLAMADFQYLYDHPFSQKWTAYRILPLKVQPHTNSDGHDVYKVDNKSLQTPRFHPSTFLEKLQLEALPDTKTHCHFDRHRSLPLLILRVVILDSPYNFNWSGQEGTATSFDTARIMYIAFPDAAPFLYITKPSSIGGVNSAFDAKSTRSLVVDGIPKALSRPRERVTLKATDFTSTNLSAILQTSSAGRTNAAGGGWSIYADEKKKDTPLERVLPISPLLDDIQDSNSGPKHKLHDTTESKAVKKRRRVAEGRFGNSALIHDVVGIRQLDIVLANTLVNADENDDHDEEPPKASVRLCFVGSHVFAGIRQLIEAGAIDGEKMPGWMTGEEGVTSGTVVGGRIRGHKGTGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAC9</accession>
    <name>A0ABR3ZAC9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Peptide hydrolase</fullName>
            <ecNumber evidence="14">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">LAP1</name>
        <name evidence="16" type="ORF">Cpir12675_002322</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Extracellular aminopeptidase that allows assimilation of proteinaceous substrates.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the peptidase M28 family. M28E subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="14"/>
    <dbReference type="EMBL" id="JAWDJO010000044">
        <property type="protein sequence ID" value="KAL1897534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03879">
        <property type="entry name" value="M28_AAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF56">
        <property type="entry name" value="AMINOPEPTIDASE YDR415C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 16" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 14 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 14" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0732">Signal</keyword>
    <keyword evidence="8 14" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044999345" description="Peptide hydrolase" evidence="14">
        <location>
            <begin position="19"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="15">
        <location>
            <begin position="170"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1897534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="401" mass="44693" checksum="CB3E636744D5E037" modified="2025-10-08" version="1">MLFAQVALLATAIPSINARFVEKNEVDNVSLFPQGAETETFLIELGPGETRRVTEEQKWELRREGRNFMDITETQSLGTLRAKLLAKSVFPKKCAFQKQVTPMLPTLNKDNMQANLEKFTSFHTRYFRSDYGRQSSEWLLSRIHDIIKEAGAEEAVLAVPFKHSWPQSSIIATIPGKTNSTIVIGAHQDSINLWLPSILAAPGADDDGSGTVTILEVFRAILLNKDVLAGKAENTIEFHWYSAEEGGLLGSQALFAEYEKQGRNVKAMLQQDMTGYVRGTLDKNQPESVGVITDFVDTGLTNFIKEVITEYCNIPYTETKCGYACSDHASATKAGYPSAFVIESNFDVSDPHIHSTDDLIKYLSFDHMLEHARMTLGLAYELGFTDFESLEKEAQLGAREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB21</accession>
    <name>A0ABR3ZB21_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Tethering factor for nuclear proteasome STS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">STS1</name>
        <name evidence="8" type="ORF">Cpir12675_002356</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 6">Binds the proteasome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cut8/STS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000045">
        <property type="protein sequence ID" value="KAL1897500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1590">
        <property type="entry name" value="Tethering factor for nuclear proteasome Cut8/Sts1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013868">
        <property type="entry name" value="Cut8/Sts1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038422">
        <property type="entry name" value="Cut8/Sts1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28032">
        <property type="entry name" value="FI02826P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28032:SF1">
        <property type="entry name" value="FI02826P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08559">
        <property type="entry name" value="Cut8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="50"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="300" mass="33100" checksum="29103DA98ED43D34" modified="2025-10-08" version="1">MSAVLPPHNVIFPHNHEAPRRSPQRSMSPFNMSTSTSRKRKADDDDEMTISPSASPAISQRQILRPQKRNRHSELVGRQLSMPRLLETLDPAQLRTVLGQICQHHPEIGHQVAMSAPRPTVSSVLGLLDEYMGRLKDAMPYGNSSPDYTYNRVKQPLIALIDALADFTMQFLPPVESQVSASLQFLDGATKIIHSLPNWESPSYTHHKDTAYDEIAKAWALVFNEASSRGAGFQLSTGGWEQTINRHNSQSNGRLASAVIAMQGAANWPTPNNSANDASCIRNQLMSGTYGLPGVRVGPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBR1</accession>
    <name>A0ABR3ZBR1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Vesicle-mediated ER to Golgi transport protein</fullName>
            <ecNumber evidence="10">2.1.1.319</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">USO1_1</name>
        <name evidence="10" type="ORF">Cpir12675_002295</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:48096"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11991"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61897"/>
            <dbReference type="EC" id="2.1.1.319"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:48097"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-arginyl-[protein] + S-adenosyl-L-methionine = N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48100"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11990"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65280"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:48101"/>
        </physiologicalReaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.319" evidence="10"/>
    <dbReference type="EMBL" id="JAWDJO010000043">
        <property type="protein sequence ID" value="KAL1897567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035242">
        <property type="term" value="F:protein-arginine omega-N asymmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055135">
        <property type="entry name" value="PRMT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006:SF116">
        <property type="entry name" value="PROTEIN METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06325">
        <property type="entry name" value="PrmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22528">
        <property type="entry name" value="PRMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51678">
        <property type="entry name" value="SAM_MT_PRMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 6 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 6 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein arginine N-methyltransferase" evidence="9">
        <location>
            <begin position="357"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="148"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="185"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF22528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1897567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="550" mass="61895" checksum="4720D0F2065B2DFF" modified="2025-10-08" version="1">MSTEQNLHKAETLSQGSSSSDEEGWQDIEPDYEEGTVVKSFFDEKTFPDAKAMMIYCREKHGFDFMATRRRLNLDFHGAVKLSNYVRLMAQESNATLGDISADDLNDDLYLKPVLNNDGLLMSLDEILDEDDEANAELNTSPPSDIPVAQLLKKNELLEEQLGKLTEQFASFRQTVAATLDKRWGDDVTSENPDKPKNVKSGPAIPRSIDNNYFESYAGYDIHETMLKDTVRTEAYRDFVYSNKQIFKDKIVLDIGCGTGILSMFCAKAGAKKVIAVDNSVIIDKARENIFANGLSNIITCIAGRIEEVNLPVEKVDVIISEWMGYALLYEAMLQSVLWARDKYLQPGGLLVPSLSTLVIAPVSDTEYMNDCVDFWDNVYGFDMAAMKKKAMADARVEHMRPYSLAGSSSMFKRLELHDVREADLVFTEAWESTITKDTDALHGFLVWFDIFFTSRTETVPTDKLEPAKWHDEGTGKIAFTTGPQGKETHWKQSLMLIDPENPQPVLKGGDKISGKVVWSIPKDDPRSIVVEVSWKIGEGKIHKQAWDLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCA0</accession>
    <name>A0ABR3ZCA0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Origin recognition complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ORC1</name>
        <name evidence="9" type="ORF">Cpir12675_002019</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">ORC is composed of six subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ORC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000035">
        <property type="protein sequence ID" value="KAL1898311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001025">
        <property type="entry name" value="BAH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043151">
        <property type="entry name" value="BAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054425">
        <property type="entry name" value="Cdc6_ORC1-like_ATPase_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050311">
        <property type="entry name" value="ORC1/CDC6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763:SF23">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01426">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22606">
        <property type="entry name" value="Cdc6-ORC-like_ATPase_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00439">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82061">
        <property type="entry name" value="BAH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51038">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAH" evidence="8">
        <location>
            <begin position="88"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1898311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="753" mass="82936" checksum="10AD6C8C1FFF176E" modified="2025-10-08" version="1">MVRPSRSQSRQTASAEPTVAGSVSSEDSRNHANVNGVDINSEKGPANTSDEDEDLDWDWVYDGQDKDGRTYGRARPSNQITGARLGQFECRLGDIVLLRADGLSDTWVAIISDFTLDDNGEKAAIFVWFTGGKEIRNNERKIQDYYPNELYITSASDINPLESICGKANVMSEASYRKSFPTGKIPRSSPHFGKTFICRRGCNMRTTTYTNVFVWENMYRGFRDLKSLLQYVTEGTKLSRKLKQDLDATFVPGDETAPQKQVPMTPRTRRINVNATPSGSRQRRGAKKALEFTPLATRIIPMDTIQASPFQQARTQLHVAAVPLTLPCRENEFAEVYFHLEKAISNGTSNCIYISGTPGSGKTATVREVIARLEDSVLNDELDDFIFVEINGLKITDPHQSYAVLWEALKGERVSPAQALDLLEREFSAPNPRRVPCVVLMDELDQLVTKNQGVMYNFFNWPALRHSRLIVLAVANTMDLPERTLSNKISSRLGTYIITRLYPSFRVLLTLLGLTRIPFPGYNHEQLMEIIQSRLEGVQGNIVEPDAIQFASRKVAAVSGDARRALDICRRAVEIAESSLNNAVPPTPSRTKPGFAPSNGRVTIQTIRQAINEATSNPVQQALRALPLAPKLLLSALLIRLRRAGIGEVSMGDVLSELGSMLRSSSGRNSEDLVASLLGPGAVSLTPQGTGALAPTALMAFQDAALGLVAAGIIVLEAHKVERPSKVRLAVPDDEITMAFHDDPEIKEIGITV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCK6</accession>
    <name>A0ABR3ZCK6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Perilipin-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000043">
        <property type="protein sequence ID" value="KAL1897553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17316">
        <property type="entry name" value="Perilipin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1897553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="188" mass="20559" checksum="4110BEE59D069337" modified="2025-10-08" version="1">MATADASHKTLTVEVNSAFLKHLLDYPIVKDSVDTVTTSPYTKNTYVQKSIALGDSAYKTFAVPVLGYISKPYQYVQPYVKKADSIGDETLSKVDARFPAFKKPTGELYAEARSTVLMPYQKTVEGRNHILSTYNAERKKLSADGLVAYTKALVGTACVLGSEGLAWANSTFKKASEEASKPTEVDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD02</accession>
    <name>A0ABR3ZD02_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Vacuolar sorting protein Vps3844 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_002119</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000038">
        <property type="protein sequence ID" value="KAL1898032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053065">
        <property type="entry name" value="Archenteron_Induction-Rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024382">
        <property type="entry name" value="Vps3844_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36853:SF1">
        <property type="entry name" value="DUF3844 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36853">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12955">
        <property type="entry name" value="Vps3844_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045478639" description="Vacuolar sorting protein Vps3844 C-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar sorting protein Vps3844 C-terminal" evidence="3">
        <location>
            <begin position="295"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="400" mass="41821" checksum="895749A37BCB29C6" modified="2025-10-08" version="1">MWSSMSALVAFLGTTSAALSGAPAYILQQHPQQASAALLVSQNTPPAVNVQTARLILEQRLNTPNVFLSDGIDEASRETAISAINAFGRAPKPLFGEPSAYASDVDSQSTGVQLDASQLVVLVEGLSDAEIEQTAQLAGLKTAFTVSDPPSSMANSVLVREHPAANAGKKCELSEAVNPLSAACWHGTSSLLRFDAKKDATLLSTLQSVIPKLAGLASSGEMESVFVFFPESARSSKLNSWDTAATELRRRQAEEAVMTDKIQPTNETPKTNLAGTSAKPAPGALFVSSKDVPECFKDAEACSNGTNSCSGNGICVNRWGKDVGEACFVCNCVSVKEGGKRSTTGYAGKACEKLDYSTPFALFVGFSIAMVGILAFSISLLFQVGEEPLPGVLGAGVAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDD4</accession>
    <name>A0ABR3ZDD4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Septin spn4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">spn4</name>
        <name evidence="6" type="ORF">Cpir12675_001930</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000033">
        <property type="protein sequence ID" value="KAL1898385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01850">
        <property type="entry name" value="CDC_Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016491">
        <property type="entry name" value="Septin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006698">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="5">
        <location>
            <begin position="27"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="317"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1898385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="384" mass="44451" checksum="E9B57CFDABECEB29" modified="2025-10-08" version="1">MASTADSASAIGIANLPNQRHKIVAKRGASFTIMVAGESGLGKTTFINTLFSTTIKSYADHKRRHQKQVDKTVEIEITKAELEEKFFKVRLTVIDTPGFGDYVNNRDSWMPIIEFLDDQHESYMLQEQQPRRQEKIDLRVHACLYFIRPTGHTLKPLDIEVMKRLCSRVNLIPVIAKADTLSPADLSKFKTRIRAVIEAQNIKIYQPPVEEDDDAAAQHARSLMAAMPFAVIGSEKDVKTSDGRIAKGRQYSWGVAEVENEDHCDFKKLRSILIRTHMLDLIHTTEELHYEAYRAQQMETRKFGEARPRKLDNPKFKEEEETLRKRFTEQVKIEEQRFRQWEQKLIAERDRLNKDLEHTHAQIKQLESELEQMQGAAVRSHGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDW6</accession>
    <name>A0ABR3ZDW6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000035">
        <property type="protein sequence ID" value="KAL1898286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052711">
        <property type="entry name" value="Zinc_ADH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45033">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45033:SF3">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G13270)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="13"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="365" mass="38762" checksum="C289214E75BCBC78" modified="2025-10-08" version="1">MTSRVLMIEKTEGKPGNVYYPLRLTYVDIPRAGPGQVVVKMLAASLNHRDLFIRKHLYPAISFASPLFSDGYGTVTEVGPSCKTPSLLGKNVILAPFVNWSEASEGPEDARSFTVIGASKLTPLGTGTDFVVIDEAALELAPEHLSAAEGATIPTVGLTAWRALVTKTNNALPGRNILITGIGGGVAISALQFAAAMGCAVFVTSSSNDKIEKAKTLGAKGGVNYKSDSWVADLQAQLPKDRPYIDAVIDGAGGSIMSAAVKLMKAGGVVASYGMTQGPKMDWLMQAVLKNIDLKGCTMGSRKEYADMMQFIRDKKIVPVVSRVVQGLDNIGDVEGLFRDMDQGIQFGKLVIEFGNPGETTPPHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE43</accession>
    <name>A0ABR3ZE43_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">t-SNARE affecting a late Golgi compartment protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">tlg2</name>
        <name evidence="13" type="ORF">Cpir12675_001694</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000028">
        <property type="protein sequence ID" value="KAL1898941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15845">
        <property type="entry name" value="SNARE_syntaxin16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006012">
        <property type="entry name" value="Syntaxin/epimorphin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF83">
        <property type="entry name" value="SYNTAXIN-16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00914">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="327"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="12">
        <location>
            <begin position="253"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="21"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="207"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1898941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="350" mass="39607" checksum="D1CF1F1D3592F43C" modified="2025-10-08" version="1">MWRDRTNLYISYRQSYAHHPTKRSKYASNPIGRLGSPIPDTFPGTSSAVSDDRRGLLSAGAFEDDGDAVIEMDLLPPRWADVSDEITEIIGDIARKGQTLERLHQKHVLPGFNDEEAKREQEIEIEKLTQSITRRFHECHRCIQRIGHMVTESQDAGTLTRAEEIMAKNIQISLASRVQEVSASFRKKQSLYLKKLRGMSGMGDRSVSPNPSSQAYNADPSLFESDADRSFSQSTLRGISEQKQLQKFRGANDAIISQREREIEDIAQSIIELSDLFRDLQTMVIDQGTMLDRIDYNVERMAVDIKAAEKELVVASGYQKQHIKRKIILLLLLLIVAAIILLVIKPKKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEQ5</accession>
    <name>A0ABR3ZEQ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000029">
        <property type="protein sequence ID" value="KAL1898727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="368" mass="41077" checksum="3E4EE58E038533CE" modified="2025-10-08" version="1">MVATVANWVDAFRIDRYLQRTIDFSAYTWDTLTQIEPSSEALVQTHTLLTARTSRAGNAPTRSLSHISGPNSTSAPKFSSTPLATGSKVARLCVYPVIPCNGIEIAKSKIVRRGMQYNAIYAFIKQAPNTKMWDLLLPTECPNLGRLFVEIWIPDIIKTRGSLDKAPNEAFVLISFPWVDRGWQGLLALLLAKITKGFRGQPDKEAILPVEFPTQREIQNVGYQYEEVNMGERVVKLLNMGRELPEEIAMFLGVNGKLGLARIDRYLDGENGTREIRSLCMLPEKLDEDSTDWVIRRPNITVSQTLPGSGQYISKISFDQGDAMFSSDWSYDVSRYSDGALHIVPQPSEEPGRSTDSWLEVGMGIVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF92</accession>
    <name>A0ABR3ZF92_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA endonuclease activator Ctp1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_001743</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000029">
        <property type="protein sequence ID" value="KAL1898740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013882">
        <property type="entry name" value="Ctp1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033316">
        <property type="entry name" value="RBBP8-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15107:SF0">
        <property type="entry name" value="DNA ENDONUCLEASE ACTIVATOR CTP1 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15107">
        <property type="entry name" value="RETINOBLASTOMA BINDING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08573">
        <property type="entry name" value="SAE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA endonuclease activator Ctp1 C-terminal" evidence="6">
        <location>
            <begin position="606"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="181"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="417"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="469"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="536"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="704"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="59"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="181"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="488"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="540"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="554"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="720"/>
            <end position="741"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="754" mass="83132" checksum="09D6A68D7C2CC4AC" modified="2025-10-08" version="1">MSLSSWHEKGRPALFEALATVCDRIDEEIEAEVHNKVSTCKHNLKPGELEALQVRATEADRLEKDNHRLREALSRLQKEKAAQELSKTPLGAAVTPQALTVQDTNTTANTIKLESSLRTLKKNFLTAKDSLIKRKNERDQWIEYSKNLEKKIASLKSKLKSAQTTVTSGLGVVSGDQAGENTNDTIAIPNTSFSSDAGNGGHRGGANITTTAPTGALETGEFELPPISSMAPPPSTINEERICDSQLPDENETLTSDGATDSATQNLPVLSTVTSVSANVQIKEEPSSDDRIVVVQERAVKKRKYNSEHTGRSPAISRIKEEHFSSDSLLSADMHGFSPQESVDLDNVGGNVETPRKGRTQEDLACSLNVEVYSSQPSVIPDSPYQPASDERTPTAARSHIGATHTYTTHIDLLAQSGGTPLQGRAGRASLETSGDKTTPVTAIKSTRTMPRSFAAALTSPLNDVYGASDLRREGRRTSLGSTKIGRTPSTNITSGAPIQRSSHGPPNSGSNTLAGLDVPEPRRLPFDNVTISRSSLNRSFHEEPESISRRNDASTSRGPNMSFSGALETTPTHVRTGAIRTKRPHELQPEDFKINPKFNDGRSYAYTEVVRGRAERAALPGCTDPTCCGQDFRMLARSERGTAPRTAEQRVEDKLYLERYLGDECFRLFGMTREELDELWIEAKAKELADRWGKHRHRFSRMKSPPGFWNPDFPTTQEARNERDEADRRKQQEVEGRYREAMRPGGRWMFRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG90</accession>
    <name>A0ABR3ZG90_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dienelactone hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001266</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000019">
        <property type="protein sequence ID" value="KAL1899686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630">
        <property type="entry name" value="DIENELACTONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630:SF80">
        <property type="entry name" value="DIENELACTONE HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="2">
        <location>
            <begin position="77"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="325" mass="34989" checksum="0916592FD0BE7805" modified="2025-10-08" version="1">MTTPEDATRAPESDAQEDKATPPSSSVDASGPTPAMGDCCTSDRPTPSGKASTGEIVKINDVECYISKPADYPHVPARLLLLLTGGTGLHSVNNQIQSDKFASEGFLVIMPDLFGGDPAPNAAGLENELDLSSTSFLDIFKVRAAETAKSFMIDMWLARHTQDKVMPLLHHVIDGCKEKYSAVVAEGQGIYAAGYCFGARYVLLLAKENQSLYGEAMPNEEAGGLRKGPLIKAGALAHPTSVSHADFDNLKAPLSFICVENDPLFPDEIRAIGEDTMEKASLEHEVKVYPGVPHGFAVVGDYPQAEIKEAQEVAYDQMLDWLHSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG95</accession>
    <name>A0ABR3ZG95_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pre-rRNA processing and 40S ribosomal subunit assembly</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FAF1</name>
        <name evidence="2" type="ORF">Cpir12675_001248</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000018">
        <property type="protein sequence ID" value="KAL1899748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053030">
        <property type="entry name" value="Ribosomal_biogenesis_FAF1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28096">
        <property type="entry name" value="PROTEIN FAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28096:SF1">
        <property type="entry name" value="PROTEIN FAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="303" mass="33246" checksum="4CC9399D59E86479" modified="2025-10-08" version="1">MVSAPHKRKAPASEPTTGPEAAESVQDIFRRHFEAQFAPLPEPVKAAVTEDENERGEDLQDEDEWDGLSAEEGEDNEIVEVVDYSSSTPQVSMTMSKHERKAFMSTKPTDLTASSATATEASNAASANKDDANDENSATMLKQDIELQRILAESHLLAQPVARLHVVSNTDKLFADGKLRRKTTDMRVQALHHNAHSVLAQQNVPMNIRKGRIAAQAAREDKRRREARKNGIILERKGGDSVATGGVEKRRKKSGGGPRVDMPGIGRMNGAELRISERDVRNIEGPRRGFGRDKGRGGGKGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGJ2</accession>
    <name>A0ABR3ZGJ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_001487</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000024">
        <property type="protein sequence ID" value="KAL1899294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF40">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="252"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="374"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="409"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="438"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="466"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="503"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="533"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="124"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1899294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="634" mass="71406" checksum="97770F82D6C61D2E" modified="2025-10-08" version="1">MASEKEPIEKQPIEAIHTNASPHHEEMGRHQSQHPDMKNNLAAKIRNPLDGIPYDTLMRDVEDFTREYDLTEHTEVFRRGALIAQNPSGYAQIGGRETLSEFEKTAIRDEVEHRWRMPRKLLLTIATCSIGAAVQGWDQTGSNGANLFFPKHYGIEGDKLLVGVVNAGPYISSALLGCWLSDPANHYLGRRGVIFVSANFCLWPLIGSAFAQNWEQQLITRLLMGIGMGIKASTVPIYAAENSPAAIRGALVMSWQMWTAFGIFLGTAFNMAVYHASRNVNWRLMLGAPALPAIPLLALIYLCPESPRWLMKKGRYVDAWKSIVQLRNDPIQAARDMYSIHAQLSLERQIIDNSTYFNRVKELFTIPRVRRANLSAVTVMLAQQLCGINIIAFYSSTIFEESGFNEFEALAASFGFGLINWLFAFPAFYTIDTFGRRSLLLFTFPNMMWTLIAAGLCTTLEGKTRLALVAIFIYMFAMFYSPGEGPVPYVYAAEVYPLSHREVGMGLSVAVCLGCSAILSITFPYLLDEAGKVGAFMTYAGFNAWAFIMIFLWVPETKQRTLEELDWVFAVPVRKFIRYQFDEVLPYWYKRYILRNKSAEIRPLFQVSQHEEAQNLAAQSSKDREAVAAATASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGP6</accession>
    <name>A0ABR3ZGP6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001716</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000028">
        <property type="protein sequence ID" value="KAL1898963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="240" mass="27172" checksum="0AA50120810FF66D" modified="2025-10-08" version="1">MSSPMIFEPAEQAITKHLMSSSPPVPRTKRYIRNIEQDTSPDADIEAERLWEYMIHIALDHINQAAVPEPRWTLAGEDEWNPPDTPSRPPKAAQQATVPTSISKDDIEMPDVPRGLDASCHVTAVDATEPTPPRPPVPSINAPARWKPQPRKAERNNNQAPPAARRLTKWRCARTWRPPTQRMSYFLSVQTTKRKYFNDFLEQATGPDIYTALRYTKPGQQNIIPTMTHKGAAQTTYTVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHA3</accession>
    <name>A0ABR3ZHA3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000021">
        <property type="protein sequence ID" value="KAL1899592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="323" mass="34251" checksum="2F5F782D73256A49" modified="2025-10-08" version="1">MADISGPEGTSSSSPPRHVHTSAAPSPVSLHDKHPPLDKKSSDAAISLHITDAAAHATIHASPDSSRPPDFYEPDVHEQVTVRPFDPPLTLVTNISTGTTYHPQVYYIFSDDEPDTLTHALQLANNRNPGLYDRAVIVDLQPSDADTGWTVAAASSITADWAVTSAQFMPLGGSPGPMSAGGGMRTAAAPENAANNGSDSDGDMILEITGTDALLPKSVDILVEHFPDPQTSNPLLEPGAKNYAPIVAEFDECMKKLSQVVEAGEANLQHSIRVQQQQNRVDLMHSTTESLRRKDSPNVTSADGSDVKGKGKMPAYAPPKSPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHD6</accession>
    <name>A0ABR3ZHD6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Clathrin light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">clc1</name>
        <name evidence="9" type="ORF">Cpir12675_001692</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasmic vesicle membrane</location>
            <topology evidence="1 6">Peripheral membrane protein</topology>
            <orientation evidence="1 6">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <location evidence="6">Coated pit</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="6">Cytoplasmic face of coated pits and vesicles.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the clathrin light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000028">
        <property type="protein sequence ID" value="KAL1898939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000996">
        <property type="entry name" value="Clathrin_L-chain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10639">
        <property type="entry name" value="CLATHRIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10639:SF7">
        <property type="entry name" value="CLATHRIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01086">
        <property type="entry name" value="Clathrin_lg_ch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0168">Coated pit</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 6" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="67"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="123"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1898939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="228" mass="24943" checksum="B932D9628AC6281D" modified="2025-10-08" version="1">MADRFPSLEEFDSGATQVGETSGEVPSTDDFLAREKALLGDDADQFATNDDDLLAENQAASPEAAFTSQFPDITANQSVNNDGTITGAGPSVSYNSGFSSYAQEEEEPEVIKQWRETRDANNAKRAEKFAQQREETIKEARQNIDDFYENYNLKKDKTISQTQKEAEEFLANRENTVSGGTSWERIAKLVDVSGKGVKGGASGSGKERFRELLVSLKKDENAPGASGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHE6</accession>
    <name>A0ABR3ZHE6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Inositol phoshorylceramide synthase regulatory subunit kei1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000025">
        <property type="protein sequence ID" value="KAL1899248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013862">
        <property type="entry name" value="Kei1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28077">
        <property type="entry name" value="INOSITOL PHOSPHORYLCERAMIDE SYNTHASE REGULATORY SUBUNIT KEI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28077:SF1">
        <property type="entry name" value="INOSITOL PHOSPHORYLCERAMIDE SYNTHASE REGULATORY SUBUNIT KEI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08552">
        <property type="entry name" value="Kei1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="251" mass="28008" checksum="F755FB078DBB59D2" modified="2025-10-08" version="1">MRSFSRLFRIPRPKKFLGCVGLPLAAEIIAAVLVFNKATGIYGLLAILTGYSLNALQIPTYLYCVLAIFSLVYLIPHIRKQSPFECLAFAWLYIIDSFINLALTASFAMTWYVARAAEDARADDSVTSQMPLKVSSGSLSKGASSMPHDAAFSIIIIVFATLGRFYLCFVVASFAQQCLRRHMDRVVENDDPIKQLGAPFTQDCAEGHTWRGKLARLMIGVGRSYWLDASDRDEWARSMNARFRKIADDAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHV2</accession>
    <name>A0ABR3ZHV2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Vacuolar protein sorting-associated protein 74</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">VPS74</name>
        <name evidence="7" type="ORF">Cpir12675_001398</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GOLPH3/VPS74 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000021">
        <property type="protein sequence ID" value="KAL1899625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3630.10">
        <property type="entry name" value="yeast vps74-n-term truncation variant domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008628">
        <property type="entry name" value="GPP34-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038261">
        <property type="entry name" value="GPP34-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12704:SF2">
        <property type="entry name" value="GOLGI PHOSPHOPROTEIN 3 HOMOLOG SAURON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12704">
        <property type="entry name" value="TRANS-GOLGI PROTEIN GMX33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05719">
        <property type="entry name" value="GPP34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="353" mass="39146" checksum="26339BA9811AB261" modified="2025-10-08" version="1">MSTTTSGLTRRRGGGGGGGGGGASADSEARHSPVPGHRSDNGGPETSFENSENGHKIAYDPRDMNESVERSKQPKLTLMEEVLLLGLKDKQGYLSFWNDNISYALRGCIVMELALRGRISMQKDASRRRFPLPERVIEVIDDTQTGEVLLDEALKMMKHSEKMSVSAWIDLMSGETWNLMKIGYQLKQVRERLAKGLVDKGILRTEKRNFLLFDMATHPVADGGAKEEIRRRVRNVLTQRTVVLNASEFLPEELPLRTVRTVAMVCAAYAANVLENALANLGHEARERAFVQTDDMLADYGQWPFGRKAVNNGVAANLPSLIADETNANKDRELQLEVIAACMNVFTRLDSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI84</accession>
    <name>A0ABR3ZI84_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">2-(3-amino-3-carboxypropyl)histidine synthase subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">DPH2</name>
        <name evidence="10" type="ORF">Cpir12675_000889</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the DPH1/DPH2 family. DPH2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11840">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11860">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010014">
        <property type="entry name" value="DHP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016435">
        <property type="entry name" value="DPH1/DPH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042263">
        <property type="entry name" value="DPH1/DPH2_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042265">
        <property type="entry name" value="DPH1/DPH2_3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00322">
        <property type="entry name" value="diphth2_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00272">
        <property type="entry name" value="DPH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762:SF2">
        <property type="entry name" value="2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762">
        <property type="entry name" value="DIPHTHAMIDE BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01866">
        <property type="entry name" value="Diphthamide_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01121">
        <property type="entry name" value="Diphthamide_biosynthesis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00408">
        <property type="entry name" value="Diphthamide_biosynthesis_famil"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00032">
        <property type="entry name" value="Radical_SAM_3-amino-3-carboxyp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="293"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="472"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1900423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="554" mass="60379" checksum="02F4CDAB10A1DAE1" modified="2025-10-08" version="1">MATSLSAAPVLSTPSEHVFEDPTPAARADPSLQRSANSSIRDTYEVGRSAAEIVAGGWARIGLQFPDHMLCDAPAVVQELEAEIATLCSQKQDSSDKSKTHKQPRIYVLADTSYSACCVDEIAAEHVNAEAVIHYGRSCLSPTSRLPVIYVFTRYLLNLDNAVAAFEAVFPEKDSKVVMTADVMFQDHVAPLTALLRTRGYTTLLETVVMHEPTATIPNRSIINDEASEPCGLDAEILKSYALFHISEPPTAVLLALVSRFRSLHVLPTATQLTAQDPTYTTHMLLQRRFARVLSMATAGVIGILVNTLSVLNYMASVDVLRKRIAAAGKKSYTIVVGKLNPAKLANFSEIEGWVVVGCWESGLVEDDRAFYVPVLTPFEMGVALMSEEERVWGMEWWGGLEGLKLEVPEESETKPISGTKDREYVEIDEGVDDDESAPPEFDLRTGRYVSTSRPMRMAAASEVLMVETKGGQDIRSSDGEGTETTTQKSLISRGTGDLAMVNGVLSPGAEYLRSKRTWQGLGSDFTDETSTAVEQGLRGVARGYVIGDEVDKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ58</accession>
    <name>A0ABR3ZJ58_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Uroporphyrinogen decarboxylase</fullName>
            <ecNumber evidence="3 7">4.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">HEM12</name>
        <name evidence="11" type="ORF">Cpir12675_000755</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>uroporphyrinogen III + 4 H(+) = coproporphyrinogen III + 4 CO2</text>
            <dbReference type="Rhea" id="RHEA:19865"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="EC" id="4.1.1.37"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the uroporphyrinogen decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.37" evidence="3 7"/>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004853">
        <property type="term" value="F:uroporphyrinogen decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00717">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00218">
        <property type="entry name" value="URO_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006361">
        <property type="entry name" value="Uroporphyrinogen_deCO2ase_HemE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000257">
        <property type="entry name" value="Uroporphyrinogen_deCOase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01464">
        <property type="entry name" value="hemE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21091">
        <property type="entry name" value="METHYLTETRAHYDROFOLATE:HOMOCYSTEINE METHYLTRANSFERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21091:SF169">
        <property type="entry name" value="UROPORPHYRINOGEN DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01208">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="UROD/MetE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00906">
        <property type="entry name" value="UROD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00907">
        <property type="entry name" value="UROD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 7 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uroporphyrinogen decarboxylase (URO-D)" evidence="9">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Uroporphyrinogen decarboxylase (URO-D)" evidence="10">
        <location>
            <begin position="151"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1900743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="365" mass="41215" checksum="1AD12FA2C5292CC6" modified="2025-10-08" version="1">MDANFAPLKNDLLLRAARGEKIERPPMWVMRQAGRYLPEYHKAKGSRDFFECCRDPEVASTITLQPVERYAGLIDAAIIFSDILVIPQAMGMVVEMVEKKGPHFPQPLRSPDDGQYEKVLKGAVDVSKELDYVYKAITLTRKKLDGRVPLIGFCGAPWTLFCYMVEGGGTKLFMESKKWIYRYAEESKAMLQRIAEICVEYLALQVKAGAQLLMVFDSWAGELSPSAFKEFSEPFLGYISKHLPARLDEMGLPRVPMTVFPKGAWFALDDVCNLGYDVVGLDWLMEPEEAVRIRGDRKITFQGNADPGVLYGTREAITKAVQRTVDGFWSEKKGWIANLGHGITPGVNPEDLKFFFQEIHRLTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJG9</accession>
    <name>A0ABR3ZJG9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NRPS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_000741</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the NRP synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05918">
        <property type="entry name" value="A_NRPS_SidN3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19545">
        <property type="entry name" value="FUM14_C_NRPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF3">
        <property type="entry name" value="SIDEROPHORE SYNTHETASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="762"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="1422"/>
            <end position="1498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1949"/>
            <end position="2005"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="2057"/>
            <end position="2098"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1966"/>
            <end position="1987"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="2100" mass="231086" checksum="ECD04DC6433FAD69" modified="2025-10-08" version="1">MVPACDVEARGSSATIEHSQASLYINYDASVSDFRPHFLLAWLIAFCFDKDSALPYITFETASQLNDAKTQDVVPSTIIDLPPNASLALCLEDLKQKLSPSHQSSTLPVPKTIVFYESTVDHDQAKISWTYQLQILPDPRCACMSLVSQSRNPALTPQASDRRLQVFSNVLNDILNASTTSTVISSIRARSADLDLIWNWNKIVPQTATRCMHDVISEKAKAWPGSVAIESWDGNWTYAEVDSLSTRLASILLQSGVRSGDVIPLCFEKCKWTIIAVLAVMKSGAAFSLTDPTQPEGRLRTIVEQTHAKQIIVSYQQAELGVKICKNAKVIVLDTVLLLAPSLSMATLPKVPPTTPMYVIFTSGSTGKPKGVIVSHENYTSGALPRINQINYQSSSRVFDFASYAFDVSLDCMICTLTAGGCLCIPTDAERINDLSGAIRKAHANMAHMTPSVARILDPDIIPSLDVLGLGGEAISSSDAASWSKHTSIIIAYGPSECTVGCTINNTVSADCTNLGYGVGGTMWIVDANDHEQLMPVEEVGELVVEGPVVGLGYLDEPEKTAHVFIDAPGWLKRGYKDVQGRHGKLYKTGDLVKYDPRNNGSIVFIGRKDQQVKLRGQRVELAEVEFHLRKAMPQGIKLAAEVIKPGGTDPILVAFLESKVDTTNASPPPKSSSALTPLFSGFTALVSQAIIDVDKNMGVDVPRYMVPATFIPLYNLPSLVSGKIDRKKLREIGGNMTRDQLASLRVSRTNISSQEIRVEAAPETAMEEKLLILWTTLLGSKVKISLYDNFMSLGGDSLKAMKLVGLARENGIQLNISTIFQYPTLKEMASHAQFAAANALEKKEVPPFSLLSPGLDVASAQLQASELCGIPMHEIADIYPCSPLQEGLMALTAKFKDAFVAQRVVKLESDEVVARVVNAFNEATKCSDILRTRIVQLPGEGLVQVVLKGEVEWALSTTPLHEYLSLDRDDHMDLGKALVRYAIITNNGHKYFVLSMHHALYDGWSMPLVIDRINRAYDGLSTTRPSSFKDFIAYLHGIDRSSSEQFWKDRLNGATGPQFPALPYPSYQVQSDCLLEQYVTLGNRLPTITTATVVRGAWALIASRYSGSLDVVLGETLTGRNAHIDGVEDIEGPMITTVPVRIQVQLQASVMEYLSSIQAAATEQIPHEHFGLQNIRRVSPDALQACELRTGLVMHPSIGNASEVGVSRSLYPANRLMPASESEAARESLKFNTFSLMLVCSLDPEGFLVMASFDQKTVCSKALARALRQFSHVAKQMVEYSDKSLEDIQFLMDEDISELGSLSKTAASTIASAYPNIEAAWVVDPTDSSRLLALGGVGELVVQISSDLSENMEGFRAAPLKQINTPQSILGLSPEAARTVYETGKLATIDEKGQVVLKGNKNQSSISSMPPKIVSKSKSVSVTSYKQLKLRKLWAGVLRMPEDKISLGDSFFQLGGDSITAMKLVSEARLSGITLTVAKMFQSRTLYDMANAMEELQASEASSKAVIPFVLIPEEDLSEIKASARQSLRGSKHSNIMDIIPARPLQEIAVDGTVHFPRFSARYEMMYFDRPLETNKMAISCNELVRRNEILRTVFFRNAKKKCYGAVLDKIDVPILYHDVDEQFDLKDFCHDLCKIDVRSPMPHGSSFVKWFLIQAYNTAGEQTKSALIFRISHAQYDEICLPLLLRELAALYQNQPTPQLLPFSAFANHVIRTIPDSMPYWRDLLQDSEPTVLRPDIPLVRRNHYCIEREYDISGRPAEITTASIPTAAWALCLARILGKRDVVFGEVVSGRNTAFPHADTIVGPTWQYVPTRIKFTPSMTALDLLQLVQDQHMATSAHEGVGITELIRDGCWPASAEWFDTVVHQDVEHVDSLGLVNGLGGRTEILYLHEEPLREWKIQAFPKGNKMVIEVVTFESWKETAAELLDHMQDIFTRLLGQATGPLFPEDLAATSDPKHLGEIPSATDTPVRSHSPTTPDSETSSQYDGPPTPSNEYDQPPIRIHVPQDSISPISIKTAPSDCSPTDTPPIMASNPKVNSNAPDIARDLGAAQSSLIHDLERKLAQYDEINRELRERVEKVEATMEEMRLDFEVLKAKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKH2</accession>
    <name>A0ABR3ZKH2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_000754</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="230"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="48"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="334"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="334"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="371"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="456" mass="49679" checksum="E2DB25F83A3D67BE" modified="2025-10-08" version="1">MSSKAIEEAIAAGRVPEGIEDRLYKSTESQTIVAIIFVGSLSTLVVAVRLFSRLFIVKHVGIDDGLALAGVLTLIAFVVLCIILIRLGSGRHFEYIEYVMPMNTVENSEILDFAAHIIYTTSLLIGRLSGLAFYYRLCKMHNTFRMAIFIVGGLIVAGFLPQILLIIFHCLPVTGLWPYSWQPGAEKYTCLKWGLVYSVNSATSLLCDFLIFGIPIAMLKGLDMNRKRKIQLTCILLPGVFVIGISVTRLVFVIKGQWEADMSWSYNPMLAIEVSEIGATLIALSVPGIKPVFDLFCGRLKSASKISYASARSRFQPNSQHLSSTENLKSMYHRNREGHGRGGFNRDFELESTGSGGSGQSDGHGLEVGRHSHHQHHHHLSNTGVTAGNGAGTGAAICAGTGTVVTAGKSELVSSVASNEDHIRSGSDAILVQVDFGIDEERGEPIPKDYGLKHFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKR5</accession>
    <name>A0ABR3ZKR5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TEL2-interacting protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_000529</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052587">
        <property type="entry name" value="TELO2-interacting_protein_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057567">
        <property type="entry name" value="TPR_TTI1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057566">
        <property type="entry name" value="TPR_TTI1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016441">
        <property type="entry name" value="Tti1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049362">
        <property type="entry name" value="TTI1_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18460">
        <property type="entry name" value="TEL2 INTERACTING PROTEIN 1 TTI1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18460:SF3">
        <property type="entry name" value="TELO2-INTERACTING PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24181">
        <property type="entry name" value="TPR_TTI1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24173">
        <property type="entry name" value="TPR_TTI1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21547">
        <property type="entry name" value="TTI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005250">
        <property type="entry name" value="UCP005250"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TTI1 N-terminal TPR" evidence="2">
        <location>
            <begin position="22"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="TTI1 C-terminal TPR" evidence="3">
        <location>
            <begin position="791"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="793"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="835"/>
            <end position="875"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1130" mass="124949" checksum="FE3543FA721C0499" modified="2025-10-08" version="1">MTGPTPVRQTSHVTIAARTEFFQQIKPCCVSISKTASKSEQSALDSRFLINLVQELLDHLSAQVQRDSSALDKNLADYIFFPLSHIFKYQEKHPLTLIELALRCLTIIIFHGWKSNIEPKLVQQLLLFLTFVIGGVPSQTQTRSISEEATLESLRVLKTLIIATGKSAAASASLVDASGIPALGHAIAVLLDCVSDGKTPQIQIESMKTLCAFFEAVRDDAALASFLPGTVSSLAKVASTPAREKRRVLVSAIKTLQTILVRVLSDIRTRVLSMKLEKEELKKSCEPIETFADKKDNSNEQEFEGTGKGKVWTPSWLKATAGQVKMALATVLKLAKSNEDEIRSALERLCVSLLDECHKSLDNCAPLLVETAMALSDERMDQDFMTTSLPDLAMVYPELGDSIKVIVYNWATALPRVMQSTDESIKQRAVRNLQRGLKLASAMDFASATLDDAVSAALRDSIMQLIASAKIPHVVDEVETMELLSGSRKLTTTPETRLSKFRPVIMNHDSQTTIRGEILDLLRSMGSTSQQVKLATEMVDYLQRSMGDSQASAFWLSLELFKAAFQQDADIDAFLTFSDGPSESEAAFNELYTFSVTVLDSHSNSQHIDWRVEALALETISLAASRSKEDFRPELIDVLFPMTSFLGSENVQLRHHAIVGLNLTAFYCGYSSVSELIIANADYMVNSVSLKLNTLSITPATNKVLQMVVKLAGPRLVPFLDDVVTSIFSALDNYHGYPTFVGSLFNVLNEIVNQGVKSDQLLLENSPADDMLIEKKKGPKHWMTIPEVKQALARHKEQRLRREKEDQELDNIASHPKRPWKASYYKQSSRVQEIFDRKDQQNAEATEGDPERKLGEEEGEEEPPQLTEPEKPSPTPTYAILSKIAKLTQHYLTSPTPALRKSLLSLLATVSPALAPDSTAFLPLVNTVWPVIIQRLYDSEPYITIAVCETLSALCSSAGDFMSSRFRDEWKNRMHSWMVRAKKDASASGQTNILTAVTDSFSPGIIVPLQNELPSANPNAAISGSALRAGGAMPMSSLGRFSQATKVWEATVQLLVAMLRHIRIEDGMYDEILELLADRLNDEGVRSALETINTDAVWLALYERGQLPTECLLRPAGEGFEFLDLAKVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL28</accession>
    <name>A0ABR3ZL28_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Acyl carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ACP2</name>
        <name evidence="15" type="ORF">Cpir12675_000790</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Carrier of the growing fatty acid chain in fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl carrier protein (ACP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01217">
        <property type="entry name" value="Acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003231">
        <property type="entry name" value="ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00517">
        <property type="entry name" value="acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002148">
        <property type="entry name" value="PRK00982.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863">
        <property type="entry name" value="ACYL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863:SF28">
        <property type="entry name" value="ACYL CARRIER PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12 13" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 13" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 13" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Carrier" evidence="14">
        <location>
            <begin position="49"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1900776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="128" mass="13751" checksum="0A98D7C7EBEE112B" modified="2025-10-08" version="1">MFRSALFAASRVAVRPAIAVAPRGLLATPARVAPIAIRSYSAAAGLGKEEVEGRIMSLLQGFDKVSNPEHIKPTAHFANDLGLDSLDTVEVVMAIEEEFSIEIPDKEADSIHSVDKAVDYIVQHPDAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL92</accession>
    <name>A0ABR3ZL92_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP synthase subunit beta</fullName>
            <ecNumber evidence="13">7.1.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ATP2</name>
        <name evidence="15" type="ORF">Cpir12675_000727</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>ATP + H2O + 4 H(+)(in) = ADP + phosphate + 5 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) and CF(0) have multiple subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="13"/>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18110">
        <property type="entry name" value="ATP-synt_F1_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18115">
        <property type="entry name" value="ATP-synt_F1_beta_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01133">
        <property type="entry name" value="F1-ATPase_beta_CD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="entry name" value="Bovine Mitochondrial F1-atpase, Atp Synthase Beta Chain, Chain D, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01347">
        <property type="entry name" value="ATP_synth_beta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055190">
        <property type="entry name" value="ATP-synt_VA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005722">
        <property type="entry name" value="ATP_synth_F1_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050053">
        <property type="entry name" value="ATPase_alpha/beta_chains"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01039">
        <property type="entry name" value="atpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15184">
        <property type="entry name" value="ATP SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15184:SF71">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22919">
        <property type="entry name" value="ATP-synt_VA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039072">
        <property type="entry name" value="ATPase_subunit_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47917">
        <property type="entry name" value="C-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="N-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="6 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 13" id="KW-0139">CF(1)</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="182"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1900851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="512" mass="54636" checksum="5D342136A6D37C16" modified="2025-10-08" version="1">MFKSGISSFARAARPAFAAAPRRAVRTPFPALNRLASTASVGNGKIHQVIGAVVDVKFDGSKLPPILNALETQNNGQKLVLEVAQHLGESVVRCIAMDGTEGLVRGAKAADTGAPITIPVGPETLGRIMNVTGDPIDERGPIVAKKHLPIHAEAPEFTEQSTEAEILITGIKVVDLLAPYARGGKIGLFGGAGVGKTVFIQELINNIAKAHGGYSVFTGVGERTREGNDLYHEMQETSVIQLDGVSKVALVFGQMNEPPGARARVALTGLTIAEYFRDAEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLAVDMGGMQERITTTKKGSITSVQAVYVPADDLTDPAPATTFAHLDATTVLSRGISELGIYPAVDPLDSKSRMLDPRIVGEEHYETATKVQQILQEYKSLQDIIAILGMDELSEADKLTVERARKIQRFLSQPFTVAQVFTGIEGTLVDLKDTIASFKAILNGEGDSLPEGAFYMVGNFASVKVKAEKILAELNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLA8</accession>
    <name>A0ABR3ZLA8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TauD/TfdA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_000586</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051323">
        <property type="entry name" value="AtsK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468:SF1">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="7">
        <location>
            <begin position="96"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="380" mass="41826" checksum="F58A4587CCA4546D" modified="2025-10-08" version="1">MAPSAIETAVEAVSVPKIKAYTKADGDYKELAPVTLAETELTGTHDGEFGAATYPHYLPTWNPNQKYPPLTPFEHYEHGKDADPTYPELLGPLVKVNHLTPFTGSEVSGIQLSSLGPAGRDQLARFVAERKVVAFRNQDFASLSIEQALEFGAYFGRHHIHPTSGSPAGHPEIHLVHRSAGSDTAADAYFANRLSSVAWHSDVSYEEQPPGTTFLYVLDLPSAGGDTIFTNAVEAYNRLSEGFKQRLHGLKAVHSGIEQVNASLSKGSIKRREPVASVHPVVRTHPATGEKALYVNPQFTREIVGYKKEESDALLKLLYDHLAWGADFQVRVKWEPGTVVVWDNRVTQHSALVDWASGERRHLARITPQAEAPYETPYEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLR5</accession>
    <name>A0ABR3ZLR5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000348</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="233"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="913"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1094"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="309"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="434"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="632"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="784"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="192"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="922"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1094"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1132"/>
            <end position="1142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1160" mass="129071" checksum="2713206ED06A9AC2" modified="2025-10-08" version="1">MNSIFENMVAHQSDTGSSLSTSKGATLKHDDNTHPAFTFRKATNVAGKFGERPGRRPPIIFDGGASAIKEPTPKTAATSSLIKTSPSKLPTVLDLDTLNKANNRKTADAIPAHDKSYGMADSDSLSCLEIPTKGLITRDNNGTCFPFADDGKSPLQSFRAMASESRSTGKIPRIPTMSPAFIVPVDDRGKTDTSSGSLSNRQTPSIVGDLETAPICNPRQLLEVHSRKTVESGYVSKAKRRSAVPSSGRKENKVSVCKFPPRPSSRASNISRRRVNIARDWASKSDDEKQLQNVASTLNAWAEHNNYQRAKFNETIDTFEKKINSLERELGDSRAILKDNEDQISELEAEKRHNEDHNNNLKKKLGQLEEKMEKQNAIINQFEQDSKTTMEQIAQLLDHVGIKEDIEDIPTRFLRATEAFDDCSNQLAEHQIALSKTERTKENSDRKLEQKDQELKALKCQYENRIGELNNEIRVKDDEILSRESRISQLVQKAEDDKSLKEQNENIDHRMNEILGHLTLVLERVESGPTTHSDLTEKLNSILLSVQGRNTELDRNDLLQEYLEKFKDLCKHTENDILMSLSDTVSKTTGSHQAQAERYLQSILQDQTCSVSKLIQEHEDRLNETITRSRTEERLSDSLKELQGALAEAQRTQHETEKELAVKSCHLESALQKINEATQLKHENHTLRETVDSLRTAKANSAEERSKSIEVLQHQLMRCISSQLQLEFDLREREKVSLDLQATLLAQEQKILAAEKALEEAASGLGEEKEKSAAQVFEIETDKIAQLNRELTHSNQRLANLTGKLKKYEAMLQDAHEALREWKSHKQSLVSLQEGLKNIGVSSVDTICSRLEALWKFKSDAITREEGEPSKNEDVVGEVSEIPHSLPAVDFKLDVGDEVFPDIDIQDILDSLDHVQGPKPTGKNNATPVETSNTTLTQPQPQPQPSAQQSALEHEELSRLRRIVIKSPGEMDPPIAPTIEEEKVTRRTAAAPTSILKFRSNEVSTIGATPGITFSDSETAFDASADRQAQLRGSFRNQYNRPVMSSTLANYSSAGVSVSALAAASASTYATTSGISTTDEIRRSLTVSKGVFTCSSSSSDLDNQNRNRVRKRPKEDEQLDGAAKNARNDHVSSPGSSSSTKSGYFKNILRSRSLSGKIMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM74</accession>
    <name>A0ABR3ZM74_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Mitochondrial import inner membrane translocase subunit tim23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">TIM23</name>
        <name evidence="6" type="ORF">Cpir12675_000535</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045238">
        <property type="entry name" value="Tim23-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15371:SF0">
        <property type="entry name" value="SD19278P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15371">
        <property type="entry name" value="TIM23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1901302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="239" mass="25042" checksum="3209188A038F4D5E" modified="2025-10-08" version="1">MSSLWNTITGGNKDKQQAQNVASHMPTSPTPAPSTPETSTSAAPTYDPTQNTGVESFLKPSAFADPTMLHPLAGLDKDTLEYITLDVASLPAGQSVIASRGFTDDLCYGTGITYLTALTLGGAWGLQEGLRRSEGQPPKLRLNSVLNAVTKRGPFLGNSAGVIAIIYNSFNAVIGAVRGKHDAANSIVAGFLSGAMFRSTKGVRPMLVAGGVVSGFATVWVIAKKALLPEEEQLPPRDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMM1</accession>
    <name>A0ABR3ZMM1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_000226</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006461">
        <property type="entry name" value="PLAC_motif_containing"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01571">
        <property type="entry name" value="A_thal_Cys_rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15907">
        <property type="entry name" value="DUF614 FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04749">
        <property type="entry name" value="PLAC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1901719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="156" mass="17354" checksum="131DC3083D8428A7" modified="2025-10-08" version="1">MDYQQQQFGGVPQQKSSWHEGFWSCFTPVGDCCMATWCPCILIGKTAARMRDPSMQSYSTFNSDCAITCGINCLTGCGWIYAMIKRTELRERYGIEGSTTKDCCATYWCMCCAIIQAEKEVKTRTQGLPPVTTAYQSMQDGMKMPSPEAAPPMTQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMR4</accession>
    <name>A0ABR3ZMR4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7603 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_000273</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056023">
        <property type="entry name" value="DUF7603"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24554">
        <property type="entry name" value="DUF7603"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7603" evidence="3">
        <location>
            <begin position="1285"/>
            <end position="1393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="168"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="455"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="645"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="812"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="868"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="896"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1037"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1107"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1256"/>
            <end position="1306"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1485"/>
            <end position="1551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="186"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="455"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="481"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="510"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="654"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="699"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="754"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="813"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="868"/>
            <end position="893"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1553" mass="171075" checksum="2C36600049FA6D9D" modified="2025-10-08" version="1">MSESFDLDLSKATASAVTSTTSTLAATTADNSLISPSAIATKPGFIHAHVPGTTTAAIDVDATTPSTAVISTAAVPNTTHPACTEQEAANGDLDENNSQIYSRFSFQFPYDSGLQEDEDLYLETRMLDLKHQTSSSPDQTKEEVYIKKAKQDNKTSGVDSPAAIVQGPIESQSSNPLVSPAPGPKQASSSSSDVEQAQRHQDLYQRLLDDAFIFSPNPPSPQQTAPVAAPKLVQHPAAAQNTLSRLSSRSSFHVLTKGLDSYFENQIEDEIAPTQSRNLFKGEQDKQIANDQKNGEARLSTATTTASLQAAAVSSRLSGTLTTEPVSVLPVHDIGNTRPPSSPPTLQRISLSSLASPIAQLQSPIAGSPIKRKPLSASASALAIRFSNPPVRKSLDKGSNVISPKLQSSVAFFQPQSLDQSLDSLDSFPLPPSVRTSKENVCEEHSKKLIASQCALDSSRSSLQNPVDTADLNTHPATALTTVPNSRNTSVSSSASKEQGVNETRLSQKEEEEEEEEEEEEQETSFGLPNIRLGYLEETQPQERYEPQGPYHYPFSPVAASPQFPYDIPPNTSSKSYHDFAYEEERESRLTLSYHQIDTIDEVTEPETSPKYRDSFQSSVYSLPTAGYASLDDREPVSRKLGPAFEVKHFTYPTRPTSTPDTSQLSAYPESPPPLPPKPEDRRLSFNTPPIPPPKPGATSAQTATITSHADPGLSSPILPLHSTAELNKPLPRSPNQPNLDQGELFVWTPGADSPTNSAFSSIPSPVSPQRTFSTDDTAEAPAVSGTYTTPKNIPAHVLAQQDAIKYLEDLQTPPSTKGLTSTNTTGSSRHEISDMEDELKAISAELAASIRREMDLEDIVDKLQSEVTNSAQSSNKRTSDYFSDSGYSSTKFSEYDQSREEIERIQRKADQEKAQIRLELTTKVQDEREKRHHLDLQIRELSAKAIRHNESTQISAADNSRLKELENQCEDLRRRLSDEREIKDNFEHLLTALKGELEVTSNERDNLRDEVVPELWARVEGLEVQNAEMSTMSYESSKIQQELKALRDENDNLRNSKFESEMKTRVTSLTRSSSVASSFKLQKAPMGLSRSNTVKGSEKATSMESKDVLLERLKDVEAQRDALHRALKSLLERQEFQNRESEKKIKSLEILQSRLLEGSPRKAGYEKEIENLKLEITVLRRRAEEAVEQKWRVENGLRGLKTDLDRAEAEISSLRTLLQANDILIPPAFNMASSASMTTPESTSVVSSESLNKALTDLQEAYQESLIRIRSLEAASTDQKTVAAIQRLETALANITADRNVAKIEADSLRVQAMNASASQTEHIKSEQVLSEHLQSSAQRIETLAAQVSEQLSLNSDLRQRLLDTVSRGEADRQANVSWVNQLQEKLRVMEEQLNAAQTATDERIAIYEEEIASLHMAQSSQLQRIGSPISGGGLRSPGMRSPGLRSPFLTGAPNRAASPLASPMFPRSPRMVNSKSFEDEAERTHLRNRVQELEKALSEAETEMQNIVGKISEAQIQALTLQEERDAALRETRKVQRALEEEMAQAKRLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMY7</accession>
    <name>A0ABR3ZMY7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_000167</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the carotenoid oxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004294">
        <property type="entry name" value="Carotenoid_Oase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543">
        <property type="entry name" value="BETA-CAROTENE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543:SF24">
        <property type="entry name" value="CAROTENOID ISOMEROOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03055">
        <property type="entry name" value="RPE65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="579" mass="63608" checksum="512FE7AB53AF5824" modified="2025-10-08" version="1">MSCFGATASAFKRSVYDLAEDSKATAKNWEAGNFDEWPNEAGLEALTEERGPVKLLTIGDIPAWAAGSLYRTGPGVYSIDVDDSGRSYDVQHWFDGLGHVHRFEIVAPKSSDSSESTSVWYSSRRQCDDFIAQVRAGATQGFSFAQRKDPCIGLFGKIMSSFSRKMVTTKNLQVTVSPDVGVYAQDSVKPLIDTVTGHTANVKSLWAATDNAYMRQIDPITLEPSPKCLTLGDIGTEFAYHSSCAHAGRDPKTGDYFNYGLKFGRVPTYSIYQLHEGDSKPRVIANIQGSGVAAAYMHSCFLSPSYFILCIPSSHLAWNGLKLLWNLNIIDTILPFNESQKCRWFVVDRHHGRGVVGRFETPAGFFFHSVNAFEDNEGHLFCEMVEYPNTDIMSSFYCNVMLDKNDSGKTFWKSFASKPGNMGALRRYQFDINAAPASGLGPAPKLVVDIPAPHVGELPTINPAYATKKHRYVYSVVTRGLSTMYDAIAKTDTVSGNVIIWSGEKGHTPGEPIFVANPESENKNAAEDNGVLLSVVLDGGNRKSYLLCLDACTMQERGRAECEFAVGLGFHGHHAKAKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNB1</accession>
    <name>A0ABR3ZNB1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Chaperonin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">HSP60</name>
        <name evidence="6" type="ORF">Cpir12675_000081</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00600">
        <property type="entry name" value="CH60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018370">
        <property type="entry name" value="Chaperonin_Cpn60_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02348">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000592">
        <property type="entry name" value="PRK00013.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009487">
        <property type="entry name" value="PRK12849.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009488">
        <property type="entry name" value="PRK12850.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009489">
        <property type="entry name" value="PRK12851.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45633">
        <property type="entry name" value="60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00296">
        <property type="entry name" value="CHAPERONINS_CPN60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="582" mass="61472" checksum="145404889E14EA1B" modified="2025-10-08" version="1">MQRAFSARSRQTALASASRLRTVQQTRFIHKELKFGVEGRAALLAGVETLAKAVATTLGPKGRNVLIESSFGSPKITKDGVTVAKSITLKDKFENLGAKLLQDVASKTNETAGDGTTTATVLARAIFSETVKNVAAGCNPMDLRRGIQAAVDAVVEFLQKNKRDITTSEEVAQVATISANGDTHVGKMIANAMEKVGKEGVITVKEGKTLNDELEITEGMRFDRGFVSPYFITDAKSQKVEFEKPLILLSEKKISAVQDIIPALEASTQQRRPLVIIAEDIDGEALAVCILNKLRGQLQVAAIKAPGFGDNRKSILGDLGVLTNSVVFSNELDVKLEKLTPDMLGSTGSITITKEDTIILNGDGSRESITQRCEQIRGVMADPTTSEYEKEKLQERLAKLSGGVAVIKVGGSSEVEVGEKKDRFVDALNATRAAVEEGILPGGGTALIKASGQALNDIKTANFDQQLGVSIIKSAITRPAKTIIENAGLEGAVIVGKIQDDFGKEFNKGFDSSKGEYVDMIASGILDPFKVVRTGLIDASGVASLLGTTEVAIVDAPEDKGPAAPMGGMGGMGGMGGMGGMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNE8</accession>
    <name>A0ABR3ZNE8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CAAX prenyl protease</fullName>
            <ecNumber evidence="7">3.4.24.84</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">STE24</name>
        <name evidence="10" type="ORF">Cpir12675_000460</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Proteolytically removes the C-terminal three residues of farnesylated proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>Hydrolyzes the peptide bond -P2-(S-farnesyl or geranylgeranyl)C-P1'-P2'-P3'-COOH where P1' and P2' are amino acids with aliphatic side chains and P3' is any C-terminal residue.</text>
            <dbReference type="EC" id="3.4.24.84"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endoplasmic reticulum membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the peptidase M48A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.84" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07343">
        <property type="entry name" value="M48A_Zmpste24p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.10">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027057">
        <property type="entry name" value="CAXX_Prtase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032456">
        <property type="entry name" value="Peptidase_M48_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10120">
        <property type="entry name" value="CAAX PRENYL PROTEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16491">
        <property type="entry name" value="Peptidase_M48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3 7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7 10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="196"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="312"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="342"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="CAAX prenyl protease 1 N-terminal" evidence="9">
        <location>
            <begin position="41"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M48" evidence="8">
        <location>
            <begin position="228"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1901590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="460" mass="52132" checksum="D82BE24949C20507" modified="2025-10-08" version="1">MMDFLKRLAAAIDRPLFPWKKLVLGFSIGQFALETFLSLRQHSVLKHTKPPKVLAHEVTQEVYDKSQAYGRAKSTFGMINSLWGQIQNIAFIQYDVLPKLWDFSSLFVAAFVPARFAGEISQSIVFVIGFIIIQQILGLPSRIYSTFVLEEKFGFNKQTPMLFVTDIIKTNLLTVAFVPPILAGFLAIIQKTGDKFFFYLSLFTAGLQVFMITVYPIVILPMFNKLSPLEEGELKSEVEGLSKKLGFPLHELFVIDGSKRSAHSNAYFYGLPWKKHIVLYDTLLEKSTNSEVVAVLAHELGHYKLGHTMSSAIIGQVHLFCIYTLFSVFVHNTSLFNAFGFYAQQPIIIAFLLFSDVLSPTDSIMKLYMNIMSRKFEYQADAFAADLGFSNELAHSLIKLQIQNLSTMEADWMYSSYHYSHPILSERLAALNWQPTGKVLVDKEEKQDIDTATTTGRDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNJ0</accession>
    <name>A0ABR3ZNJ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Cpir12675_000124</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03263">
        <property type="entry name" value="ABC_subfamily_A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF36">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12698">
        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="230"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="278"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="315"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="346"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="369"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="415"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="828"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="999"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1040"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1073"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1104"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1141"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1185"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="481"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="1248"/>
            <end position="1476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="779"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1225"/>
            <end position="1245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="785"/>
            <end position="802"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1902019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1605" mass="173537" checksum="7AA91993FC1486F7" modified="2025-10-08" version="1">MATALRQIWALMSKNFRILLVRHLLGSIVIAFVSPIIITAVFSFAKNLFASPAKYGVGSVRPIRSLPEALALAADDDRKTIAFVNNGLTGGDIDSVIGQISTTVASPDVRTVNLTDAADLAVLCRSSLRGVSRCYGAVEFHSSPSEGSGGTWNYTLRLDGALDATRIDIKKTDNDAETYVLPIKKAVDTAIASVDSDATTLPQAMDSLPYTDMTSKERDDEVTQNYQEAVINWMGVVLASGVLLITYHLTGFLTQEKETGMSRLIDSMMPVKKRWHSICMRMFAAHMSFSIINLPAWILGAIIMRQGVFTHTSPLIVILFQILGGLSMASFSVFASAFFKSAQISGNTTIIVAGGFAIMAQMLGDPNSATVAILSLIFPPCAYIYFVVLMSRFEYERIGTSLTEKPPTGQGKFELVGIAFWVFLLIHTIVYPILGALLENRLYGPNSQARQIVVDPVEVEKRDMKDTALVIDRMSKVYTPSRFNTMLSCFQKPKGAVTAVNELSLNAGRGQIIVLLGANGSGKSTTLDAISGMHQPTSGSITVDGTGGLGIAPQKNVLWDDLTVEEHISIFNRLKSPNNQATKEEIHALIEAVDLGKKRTALASTLSGGQKRKLQLGMMLTGGSAVCCVDEVSSGIDPLSRRKVWDILLAERGKRTIILTTHFLDEADLLADQIAVLSKGVLKAKGASAKLKDTLGGGYRVHVTTHGHINMTPEIPGVERVVAFDIATYIAPSSALAAQVIRELENIGLNDYRFSGPTIEDVFLRMAEEIHQESVKGFHEEMPTHGNQSADGSNPDSRLRLTQGQPTGYFRQVAVLFRKRLTVLKTSWIPHFIAFVIPIIGALLTSLLIKDQNAAGCAPSDSADDEGNEADFKASDLGSLLLIGSSSAITDNVLRTYLDSGNTSFSRYGIVPSYTLVDTMAQFTSSIRQNYSSIAPGGLFIPSSSSDTATLAYKANDYLTNALISQNTFNSLMSGLSINTQIESFATPWNPSMGDSLQLVLYMCIALVVSPAFFALYPNIERRALIRSFEYSNGVRSGALWLAYTAVDFLIFIASSVVVIVIWVAMSDAWLHIGYLFLVLVLFGLASTLLGYVASLFVKTQLGTYAYVAGFQFLVFAVYLIAYMSTLTFASVTKVDDQLLLVHYIASAFAPIGSIIRALFVALNVFSTTCDNQQLASNPTAIKYYGGPILYLVLQTILYTIILLSADGGGTASWFRKVFSRGKTPELSTDTEEGSHFEPKEPGSSVGLQVQSLTKTFGKNTAVDNISFDIRKGEVYALLGPNGAGKSTTISMIRGDLRPSGKYGGDVLVENFSVTRDLVSARANLGVCPQFDAIDHMTVKEHLEFYARVRGVADMEHSVSAIISAVGLGAFATRPAHALSGGNKRKLSLGIALMGNPGVVVLDEPSSGLDAAAKRIMWKTLQNTVPGRSILLTTHSMEEADALAGRIGIMAKRMLASGTIGELRARFGDALHIHLVSKTAPRTSDEEMAQLGHWIQANLPDVVMQDKTYHGQTRFSVPATSVLAATGGPINAQASISAAGSAPSAIGRLLVLLEDNKDMLGIQHYSVSTTTLDQVFLAIVGEHNVQEENSGEHEKRAWWKYLLMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPG7</accession>
    <name>A0ABR3ZPG7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tubulin-specific chaperone A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RBL2</name>
        <name evidence="4" type="ORF">Cpir12675_000246</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the TBCA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004226">
        <property type="entry name" value="TBCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036126">
        <property type="entry name" value="TBCA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21500">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21500:SF0">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02970">
        <property type="entry name" value="TBCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46988">
        <property type="entry name" value="Tubulin chaperone cofactor A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1901738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="124" mass="13564" checksum="C6E353840231D757" modified="2025-10-08" version="1">MPSPTPLEIATKAVIRLVKEEKSYHIELVSQLARLDKLKNEAATTTDENHSFMVKQEETAIQETRAVFQPLRLRIAAAVEKLVAQITSDEASATSEKLTAAMDAVTQGRAIMEQAVKDATIVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRP8</accession>
    <name>A0ABR3ZRP8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000064</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="84" mass="9104" checksum="A6CED9DDF2569CC9" modified="2025-10-08" version="1">MAAAVRAGDTGSFGWFLSLGATPEAVAVLNDQPVIFTVLLIVLTVLIFQGGILWYIHHATMKPEQRKAKAEKKAKKKKSAPAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Y9P3</accession>
    <name>A0ABR3Y9P3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_007008</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000552">
        <property type="protein sequence ID" value="KAL1884823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="319"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="181"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="304"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1884823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="344" mass="33568" checksum="0945BF171D55E6FA" modified="2025-10-08" version="1" fragment="single">EHKEPWSGFSSDSDSDSDSDSDSDSDSDDEDDDENENWKFTKDGKTKTTKTYPVSSGSPVHPYGNNTVPATLMTATAGRPSTTSLTNSKPGASSPIHSLGASTDAHSTSLPAFAGALDTDIIYVTSQLMHTVVVTVDCTSTTATTGADGMVTPGKCEPVVSTSFYVADVTTTAPNPTDAYAGVPAGPGPASGAHSSAPVGPSASSLVPGAAATHGASSSGSGSGSGSGSGSDSGLSSGSDSGSNSNSGSGSDSGSGSGAAPAGYANPNPFSTYTGMAQSAIPTTLPVTFSSVVAPAGPNTPATSSKSNPDSPESSDVPVVTAAATTMAASFSAVFVALVAVLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YE44</accession>
    <name>A0ABR3YE44_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000401">
        <property type="protein sequence ID" value="KAL1886063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047286637" evidence="1">
        <location>
            <begin position="28"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1886063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="154" mass="16014" checksum="100F1576A4890387" modified="2025-10-08" version="1">MRCQATLPLSPLLLVAFLLSLSSTATAIQLKDELNAGWTFGLMPRDTSSENLQIFTGALGGAEADPITKSSDSSRPYEVNGDTFPDFATAAGRSCDNQKNACANIANSGGGSFTVGDYECKSTVSAAAVTTFSDGNGQLALVTSTPELDIFCEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YF73</accession>
    <name>A0ABR3YF73_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_006847</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000392">
        <property type="protein sequence ID" value="KAL1886926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF166">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="241"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="25"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="271"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="363"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="281"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="375"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1886926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="385" mass="42800" checksum="69B5A72FC59AE731" modified="2025-10-08" version="1">MAIDKLTLGLHWAFTWLTVIIITTRLIWRKILRQPYLLGDWLSMAALLCVLARLGLIHVVLIWGTSNIPAALRVKLNFTPDEIYRREIGSKLSLANRVFYNTYLWLQKCVLLDVYQRLLNNVSWRNPALAIYLFIFLGTYTACQVTTFSECAPVQKYWQIVPPPGPCVAAQDQLVVVGVTNIVTDFMLLVLPIPLLIGLQANARLKLQLSVLFTLGIFIIAITIIRLPINSLNQSLQSSRTTWASTELFTSAVVVNAPTLYGFWNKRRQASKNASSNPTGGRTGGSTVGTGAGSYSVNGTRRGPRRPGSHLEYMTNIEGDIYNDSYEMGARRPPLGGIMQTKEVLISELSAVEAKTKAYNNLDDGASSHSSQKQMIHEETPAKGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFB6</accession>
    <name>A0ABR3YFB6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Low molecular weight phosphotyrosine protein phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">stp1</name>
        <name evidence="5" type="ORF">Cpir12675_006782</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the low molecular weight phosphotyrosine protein phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000374">
        <property type="protein sequence ID" value="KAL1886988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16343">
        <property type="entry name" value="LMWPTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050438">
        <property type="entry name" value="LMW_PTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017867">
        <property type="entry name" value="Tyr_phospatase_low_mol_wt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11717:SF7">
        <property type="entry name" value="LOW MOLECULAR WEIGHT PHOSPHOTYROSINE PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11717">
        <property type="entry name" value="LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00719">
        <property type="entry name" value="LMWPTPASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="Phosphotyrosine protein phosphatases I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphotyrosine protein phosphatase I" evidence="4">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1886988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="153" mass="17309" checksum="80A9FF4DE4E5439B" modified="2025-10-08" version="1">MAEGIFQSIARKKQYGHLIDRIDSCGTGAYHVGEGPDSRTMATLQKNGITDYVHSARKVQPSDFDRFDYIFAMDRSNLSDLQSMRQQRDKSKGEPRAKVMLFGEYSDSGKAEVVHDPYYGGNEGFEEAYKRCLAYTNNFLAALTKEKEGKEDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG48</accession>
    <name>A0ABR3YG48_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_006593</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000331">
        <property type="protein sequence ID" value="KAL1887305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1887305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="196" mass="21800" checksum="9814BB745FF0556A" modified="2025-10-08" version="1">MSITSINLTPNDLKRLSERRQWGSSIPYSPHMSNYNDQRGGRDEWVICSQSNVHAVNDIKWLNYTTIRPVHVTVRDSEKAARTPTASDGYIAGDVTVQLVSPDGKPVACYLNNAVYIEGLPFNIMSMCRVYARGGFINNLVLAESETQAKARIDLSNDRFSLPTAGTVVNPHRLIPFASYGKLDQPFVPWIGLGPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGG4</accession>
    <name>A0ABR3YGG4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_006553</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000320">
        <property type="protein sequence ID" value="KAL1887425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="15"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="55"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="94" mass="10090" checksum="38598C9CAAC8694C" modified="2025-10-08" version="1" fragment="single">MSAPARQTALRAGGACVRCRKGKTRCVYENGRAPCRNCAKGMHECFLPTDAHAHVHGQTPTRTVNRPPRESLPASANERTSAQHAPRSSGGQPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGU9</accession>
    <name>A0ABR3YGU9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Orotate phosphoribosyltransferase</fullName>
            <ecNumber evidence="5">2.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">URA5</name>
        <name evidence="12" type="ORF">Cpir12675_006573</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:10380"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.10" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000326">
        <property type="protein sequence ID" value="KAL1887369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004588">
        <property type="term" value="F:orotate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01208">
        <property type="entry name" value="PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023031">
        <property type="entry name" value="OPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004467">
        <property type="entry name" value="Or_phspho_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00336">
        <property type="entry name" value="pyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46683">
        <property type="entry name" value="OROTATE PHOSPHORIBOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46683:SF1">
        <property type="entry name" value="OROTATE PHOSPHORIBOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="11">
        <location>
            <begin position="60"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00014769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1887369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="234" mass="25126" checksum="45A8E7087162009A" modified="2025-10-08" version="1">MSSSTALPPHKAAFLKAAITGNILKFGSFTLKSGRQSPYFFNAGDFYRADLLTALSEAYATTIANAVADGLEFDVIFGPAYKGIPLATMATLALGAMGPQYADICYSFDRKEAKDHGEGGSIVGARLKGKRVLIVDDVVTAGTAKREAIAKITKEGGQVVGIVVAVDRMEKLPSPDGDDTKPMPSAIGELKKEYNLPIYAILTLDDIINGMKEFASPEDVKRTEEYRTKYKASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJI2</accession>
    <name>A0ABR3YJI2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Rho GDP dissociation inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RDI1</name>
        <name evidence="5" type="ORF">Cpir12675_006187</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Rho GDI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000263">
        <property type="protein sequence ID" value="KAL1888406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.30">
        <property type="entry name" value="Coagulation Factor XIII, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000406">
        <property type="entry name" value="Rho_GDI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024792">
        <property type="entry name" value="RhoGDI_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10980:SF3">
        <property type="entry name" value="LD16419P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10980">
        <property type="entry name" value="RHO GDP-DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02115">
        <property type="entry name" value="Rho_GDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00492">
        <property type="entry name" value="RHOGDI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1888406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="198" mass="22166" checksum="588AB3EF9A2713F1" modified="2025-10-08" version="1">MASHDDDTMPEETQGYKLSQPKQSLAAYQKMDANDESLQRYKESLGLGGGTDLSDPKDPRVCIILSLSMESEGQPPVTIDLSAPGSEATLKDKPFKIKEGVKFTMVATFKVQHEILSGLHYVQVVKRKGIRVSKDSEMIGSYAPNTDKQPVYTKRFQSEEAPSGMIARGHYNAISSFVDDDKKKHLEFEWSFDIAKDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL08</accession>
    <name>A0ABR3YL08_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_006131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000256">
        <property type="protein sequence ID" value="KAL1888567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1888567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="239" mass="25221" checksum="7010711EDE7C0E0F" modified="2025-10-08" version="1">MSRITAHTTKFARAMSLNAATAARPMVADSHHATAGLMPKYAELLNGRSTEDVSLHTRSAISQSSLYANAGSFSVQHSRGILTTHGPRYKLPTKRPLMQTFTVSASTASVAAMGPRHIDAAMMPAITPTSAVSDDGISVPLINGQDQHATSKLVEAEAAENDAATDRVVVAADPSVVSPSTPLTSVHSMGPDNVELKFSHQDPQSLHKGSYNAGDSEGGMFRDIWKGIVDDVSSTVNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM00</accession>
    <name>A0ABR3YM00_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Vacuolar calcium ion transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Cpir12675_005822</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Vacuole membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000219">
        <property type="protein sequence ID" value="KAL1889359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004798">
        <property type="entry name" value="CAX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00378">
        <property type="entry name" value="cax"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF14">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0050">Antiport</keyword>
    <keyword evidence="6 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 10" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="8 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <keyword evidence="10" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="310"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="388"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="443"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="512"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="540"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="568"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="12">
        <location>
            <begin position="250"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="12">
        <location>
            <begin position="444"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="130"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="141"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1889359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="604" mass="66531" checksum="FA1ACF26D432501D" modified="2025-10-08" version="1">MSRSRSHSRSHARYSEASTPEDLSPRIPHASGHAASPHYYHQPPAVQDEDSPYVPSANPNSQFPPSSRRRSSSRDRGRRSTSRQHSSRGSSAEHRQYAQHPQPISTTNNSDIERTASAPRVNDHYVAHDLPQPLHHRPQSARPTSTGLQSTREPQNLPRRKAVYNVARETSRSSQPGLAQQQSVPQSTMSGNPDSWIRRAGQSGRQGFHPAKFLLIVMQSTSRASMLCNFLWPVVPVALAIKYSLPDDHLLIFALSYIAMIPCANTVGFAGTEIARKLPHVFGVLIEVTFGSVVEIILFMVLLHNDKFSVIKAALLGSILATMLLCLGMCFIAGGIRREEQGFSDVVSEVGSGLLLTAGVSLSVPSIFIHSLKGDVETEDLERRTLETSRAVSLFLMLAYTVYAYFQARTHHGIFDAIFQDDEKLNEDYHVDKRKPRLTLTEAVVALSISLALVTLIAISLVNEIEPIVARHNISDPFMGLIMVPLVEKFAEHLGAINEAWDNQMNLALSHVLGATIQTALFNGPLAVIVAWCLQKKMDLTFVVFDMAMLLLAIITVGGFLRDQKSNYLEGFLCVTLYLSIAVAAFFFPNLHDPDSGATDSGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM22</accession>
    <name>A0ABR3YM22_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cullin family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_005821</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the cullin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000219">
        <property type="protein sequence ID" value="KAL1889358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1310.10">
        <property type="entry name" value="Cullin Repeats"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.130">
        <property type="entry name" value="Cullin, Chain C, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045093">
        <property type="entry name" value="Cullin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059120">
        <property type="entry name" value="Cullin-like_AB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016158">
        <property type="entry name" value="Cullin_homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036317">
        <property type="entry name" value="Cullin_homology_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001373">
        <property type="entry name" value="Cullin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019559">
        <property type="entry name" value="Cullin_neddylation_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11932">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00888">
        <property type="entry name" value="Cullin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26557">
        <property type="entry name" value="Cullin_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10557">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00182">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00884">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75632">
        <property type="entry name" value="Cullin homology domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50069">
        <property type="entry name" value="CULLIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cullin family profile" evidence="4">
        <location>
            <begin position="413"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1889358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="793" mass="91154" checksum="9CD401D633511C6A" modified="2025-10-08" version="1">MATHRQSYQPLTGAKKLVIKNRRQRPTETDQKVREYFDKTWADLSAAIDALLHGKPLRTPLDRLYRGVEAICRDGQAERLCKRLSEHTYDHLRSKVYPVLVKGNSDLPELETLNLVVLNWNIWMDRTKLVRSMFSYLDRTYLQRSKNLLQLNDLVTSQFCRIVFPSSKSLSGPNLLLGTAIIQGVCKLTDYHRWDNGKFNSILYKDSISMLHQLGVYTKIFERKFLDHSSTYFAQVAKENAVMPLIDYIVACNRLLTQETERCDVYGLDHATRFRLSDRVYQYLLREPLDRLMDYTSIGELFDTVNIETLKILYTLMVGAQSEPGPSMLKELEKPWRHYIIEAGGKIMRDTENAGDNKVSIVPRLLLLRRSLYRIVNCAFGSNDMLAHALRDSFGTFINDTANTAHLREGVSNIGEFVARYMDLLLRGGVKAIPPMLLNEATNDDKDEVMGAGDDDSQLDYQLNQALQVFRLIDGKDAFEAFYKRDLARRLLMDRSISYDAERTMLARLRSECGVSFTHNLENMFRDKEMNKGKMDHFKAWCEETKSKPKIELQVLVLSAAAWPTYPDIKPTIPLHMAQALGIFETYYKGKHTGRILTWKHSLANCVVKARFPKGIKELNVSLVQASILLLFNEVPDGQDGFITYSRIAEESKLDEAELKRTLQSLACGKFRVLTKHPKGREVEATDTFTINSGFSDPKFKIKINQIQLRETAQENKKIHERIVLDRRLETQAAIVRIMKSRKRISHSVLVAEVINMMRSRGTVDPAAIKKEIESLLDKDYLERDGNEYEYVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM81</accession>
    <name>A0ABR3YM81_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">FAD-dependent urate hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ADP1</name>
        <name evidence="14" type="ORF">Cpir12675_005859</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000223">
        <property type="protein sequence ID" value="KAL1889293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03213">
        <property type="entry name" value="ABCG_EPDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013111">
        <property type="entry name" value="EGF_extracell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF2">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07974">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="769"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="804"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="846"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="882"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="912"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="942"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="972"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1001"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="318"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="591"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="659"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="591"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1889293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1024" mass="112933" checksum="6F0673C66B34BE79" modified="2025-10-08" version="1" fragment="single">FNCLLPSNTCAQYGTCNEFNGKCDCPNGFGGEDCLEPLCGSLARGKDRPMRSNKTTCECDDGWTGINCNMCTSDTACNALMPEGDGGICYTGGDVVKNNYQMCDVTNKKIKNLLGERKPQVTFTCGKEEAVCQFQFWVDQTESFYCDLTDCTSKTEFSESTNKTSYACPNIKCSCIPDRMMCGQDGSLDIGEFLDEGVRGPARFQCSQQLGGPRNCEFKEPAMDELIQNLIGDSSIFLSCSSGECLYHTEVPGYEPPVKTINTPLIATVIAAASLFLVIIILGLWYLSRRNLQYGLIRLEESDDETSKLMADHKPIALMFENISYTINGKQILSNIQGISKPGEITAIMGASGAGKTTFLDILARKNKRGTVTGNLLVNGENVDNPNYKQFIGFVDQEDTMLPTLTVHETIMNSALLRLPRSMSQLSKEQRVMEVEKQLGIYHIRDSLIGSEEGKGRGISGGEKRRVGIACELVTSPSILFLDEPTSGLDAYNAFNVVECLVTLAKTYNRTVVFTIHQPRSNIVALFDRLILLAHGQVVYSGSFSKCQSYFDNLGYTCPSGFNIADYVVDLTMHASNTFLNSSELTSESSVDASLDATTNEPSSLCTRKSTAGETLRNTDDQSNDRLLPSCNRKRQNSLRFRQDQELFTRRKTTHNITAETMEIHDSQSPSRRNSNDIDQLDDLPPPSNQLTELESLVRSFRFSTIAQKNIQETANAVAAAQAANGDNALSGNLPYNSVLGNGYPRIGYVSQFVILSQRTWKNLYRNPMLMLTHYAIAILLAVLSGFLFYGITDDIAGFQNRLGLFFFLLALFGFSTLTSLNVFAQERLLFVRERANGYYAPITYFAAKVIFDIVPLRIIPPVMMGSIVYPMTGLIPDLSHFAKFLLILVLFNLAAASICLFIGIICKDHGVANLIGSLVMLFSLLFAGLLLNHDAIPKTALWLQSLSIFHYGFESLIVNEVVEITLIDKKYGINITVPGAAILSSFGFDTTAVWSDITKLGVFAASFVVVAYAAMHILLVEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMM0</accession>
    <name>A0ABR3YMM0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Trehalose-phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_005722</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the trehalose phosphatase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000211">
        <property type="protein sequence ID" value="KAL1889600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03788">
        <property type="entry name" value="GT20_TPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01627">
        <property type="entry name" value="HAD_TPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1020">
        <property type="entry name" value="Trehalose-6-phosphate phosphatase related protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003337">
        <property type="entry name" value="Trehalose_PPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00685">
        <property type="entry name" value="T6PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="TREHALOSE-6-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788:SF123">
        <property type="entry name" value="TREHALOSE-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00982">
        <property type="entry name" value="Glyco_transf_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02358">
        <property type="entry name" value="Trehalose_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="57"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="64"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="960" mass="108284" checksum="2DE00BA172CCB569" modified="2025-10-08" version="1">MIDSDSSRIPHPLDLTAAADIDHQATENEAATPGIDSATYNNPISQSLEAQDSYFNRDDGFVNHSETANDPENTGAAQNGVIDSESHPLSQTQRNRRRRESLSTIRAANPSLSLSGNIISATFNIPHSLKYHSKDDGDWELTPRHGQSALFDSLSYLSSEHTPWNHNVVAWTGEIEPAVVTDQGSSACQSTAPYSALSAPVPVDVESRSNDAPASDGLFISKAAQERLEYKLSHSRTIKTVPVWLADEEDESDAGIRLKDQSRWRRYAQDELYTLFHYKQHEPTNGRRERLHWIDYCHMNQQFATKILEIYKPGDVVIIHDYYLMLLPSILRQRMPNMYIAFYLHCPFPSSEFMRCLPRRKQVLEGVLGANLVGMQAYSFCRHFTSSCTRILHYPNNNDTIEAFGIRIQVGVFPIGIDVAKVENYAWNDEVEQRYKSLKTLYAGKKLIVGRDRLDTVRGVAQKLQAFERFLELYPEWHERVVLIQVTSPTSIESDDPENRTATRVNELVMKINGTYGSLSYSPVQHYPQYLNPAEYFALLRAADIGLITSVRDGMNTTSLEYIVCQRDGCGPLIISEFSGTAGSLRDAIHINPWDLTGVAMEINNALTMPESQCKSMQQSLYNHVATRNVQSWSDALLRRLVHVLATSKATVSTPLLDRTALFRQYISGEKRLFMFDYDGTLTPIVREPSMAIPSERIIRALQLLADDPNNMVWIISGRDQEFLQQHLGHIAQLGFSAEHGSFMRHPSSQEWENLAEKYDMGWQKEVDVIFQKYTDMLPGCHIERKRCALTWHYRQAHDQDRALAMSRECQKELELEVGQKWDVEVMPGKANLEVRPTFINKGEIVKRLVKSYTGNDASGKLEFALCVGDDFTDEDMFRSLNACSGREMQKDHVFTVTVGTSSKMTLAGWHLLEPEDVIDCAVLLSTAGKHGEDLAAIGDVNMAVVSEIEGVGAVPKMQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMX2</accession>
    <name>A0ABR3YMX2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">PRP5</name>
        <name evidence="16" type="ORF">Cpir12675_005879</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000226">
        <property type="protein sequence ID" value="KAL1889213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17953">
        <property type="entry name" value="DEADc_DDX46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056149">
        <property type="entry name" value="PRP5/DDX46/KHDC4_KH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23469">
        <property type="entry name" value="KH_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="15">
        <location>
            <begin position="525"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="556"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="761"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="270"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="909"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="11">
        <location>
            <begin position="525"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="38"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="146"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="173"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="216"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="270"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="340"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="933"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="961"/>
            <end position="970"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1889213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1168" mass="128711" checksum="C0CC5231067EF860" modified="2025-10-08" version="1">MARLRDSRSPSPGRHRKEDDRRNAHSSRDYRRRSRTRSPIDRRYRDRDARGSRRGDNRRRDRSIDRRDNDHYRGCDRRDRRDRDRNRDRRGSRDRLDTRDKNRDYDKDNDRDRDRNRNRDKSPPRNRDDRRPVRDGSPPRHKDNAATPSSQSRVGSAAPEQTKTTAVAPQQSEADKKADRLTRLEAWKKKKEQNREAEAPASQARKILADMDSKSVRSPSAAPSTVTLGQSPTPEATTPAYSGKFDPKVIAKKSAPARASPLTFGNMGKKLGGIAPGNGPGNLPSKPQARASTLPANRGISGFGFGKVADAKGPSKRKIDLDEEETSQRKLTKLPSLPLENDDTLWADQDDEEEDDDDEVFGGTEEEAIAAARAAHEKRILEKTAAESEAMTVDIAVPTAVEAMEVDEEDVDPLDAFMANLASDKPVAQKSFHSKSVPEPEAYYSDEDATYNEIEPDKTAAPVRRKKTKDIPTIDYSKLSLNPVRKNFWVEPVELSLLTEDETADLRLELDGIKVNGKDVPKPVQKWAQCGLSRQTLDTIDALGFDKPTPIQMQALPVIMSGRDVVGVAKTGSGKTIAFLLPMFRHIMDQDSIKENDGPISLIMTPTRELAVQIHRDCKAFLKTMNLRSVCAYGGAPISEQIAELRRGAEIVVCTPGRMIDLLAANQGRVTNLRRVSYVVLDEADRMFDMGFEPQVMKIFANMRPDKQTILFSATMPRLIDSLTKKVLKNPVEIKVGGQSVVAPEITQIVEIRNDKSKFIRVLELLGELYEEDEDARTLIFVDRQEKADDLLKELMMKGYPCMSIHGGKDQVDRDSTISDFKKGIVPILIATSIAARGLDVKQLKLVINFDAPNHLEDYVHRAGRTGRAGKTGTAVTFVTEDQENCAAAIAKALEISGQPVPERLNEMRKAHREKVKSGKAKDTSGFGGKGLSRLDLEREAARMRERKTHKADDDDDNVDEEKKEKKEKILSVGSAASAIISRDAAKAAAAATSEDSGKTDSNSAGSVVKAASASGSAPIAVGGKGGKNPLDRVTSAISAINSRLGKAGQLRTGQPIDNKGPDAGAFHATLEINDFPQKARWAVTNRTNVAKILEATATSITTKGSFYPLGKGPDAGQDPKLYILIEGDTEMSVRLALVEMERLLEEGTKAAEDAASRAPVSGRFTVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMZ0</accession>
    <name>A0ABR3YMZ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000226">
        <property type="protein sequence ID" value="KAL1889215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022185">
        <property type="entry name" value="DUF3712"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046368">
        <property type="entry name" value="Tag1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895:SF1">
        <property type="entry name" value="LIPID-BINDING SERUM GLYCOPROTEIN C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12505">
        <property type="entry name" value="DUF3712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="357" mass="38875" checksum="2156BF357672080F" modified="2025-10-08" version="1">MTASLQESRVSDGSNSKNLETPAGVAAAVPLTRKQKIIRHFKKWWWAYLLGQGVIIAIFLPVTLYVIVPKLMQNRVDDSKLNITRIDMSNTRANSFTLGVDSQIHTPGSIHATIFPFDAYLSLDVDEDYPFGLVRFPKNRSSKNTSVTVEHTIEIINMTSLTRFNTHLLAGETVGLRVKGKPKLKLSGLYIKYKLKFNKVVQLTGFNMFKGLSVSNANISLSATNNFRADTSIPNPTVLTLDVGNTTFSNMFNGSSIGNVYIDNLILRPGMNNYSIRADIDQTPVTNAILQEPYCETGIMPFGLVGQAVSNGGDNITYFSDALAAGEVSVNIDIGSALSNLGLNVTCSSNSSSSSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN22</accession>
    <name>A0ABR3YN22_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">I-AAA protease yme1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">YME1</name>
        <name evidence="16" type="ORF">Cpir12675_005740</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000212">
        <property type="protein sequence ID" value="KAL1889547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19501">
        <property type="entry name" value="RecA-like_FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="entry name" value="Peptidase M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01458">
        <property type="entry name" value="FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005936">
        <property type="entry name" value="FtsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048438">
        <property type="entry name" value="Yme1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076:SF97">
        <property type="entry name" value="ATP-DEPENDENT ZINC METALLOPROTEASE YME1L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076">
        <property type="entry name" value="METALLOPROTEASE M41 FTSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21232">
        <property type="entry name" value="Yme1-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="FtsH protease domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 16" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="15">
        <location>
            <begin position="296"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="695"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="242"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="700"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="710"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="734"/>
            <end position="747"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1889547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="747" mass="80802" checksum="33B9145FC67344C7" modified="2025-10-08" version="1">MIRNQALVATNRLRPGVQRTMMQQLAAANSNLPLRTIATSVASLSAASATIPNSLRSLSTLPHAWRSSTTSFRPLQHLRNLTSASGGIPRSMLASREAAANRSPGSATAQNSFYQLLLKANMPAIVIERYQSGLYATDGAANETYARALRMVKNTGASDNQYAMNETAQAVGQSVAARSVGGSVASIRGGAGTKSGPLYVVVDESRSSTLFRWVKFLLSFGLSTYLGLVVISLAVSLFDDMNKRRPGNKTESEVKPKSQTTRFGDVHGCEEAKDELQELVDFLKNPDKFSTLGGKLPKGVLLVGPPGTGKTLLARAVAGEAGVPFFYMSGSEFDEIYVGVGAKRVRELFAAAKSKSPAIVFIDELDAIGGRRNARDAAYVKQTLNQLLTELDGFEQNSGVIILAATNFPELLDKALTRPGRFDRHVTVPLPDVRGRLAILNHHVTKIKAAPDVNLQALASSTSGLSGAELENIVNQAAIHASRAKAKNVNMLDFEWAKDRVIMGSERRSMVISAKEKEMTAYHEAGHALVLLFAENPPNELYKVTILPRGPTLGHTAFLPEMDKHSYTLSDYLSMIRVSLGGKMAEELRYGVDHVTSGVSSDLEKATKIAFSLVSQFGMSQKLGNMDYSENYQNLSSETKSRVEGEVQRMLNESYENVRELLTKRRKELDLLAQALVEYETLDRREVELVIRGQSIPGRQPLPPGPMAVPLPLDGAMPGSGEAFSSEQSSSTRTPPPVPPAPTAPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNB1</accession>
    <name>A0ABR3YNB1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpl13</name>
        <name evidence="5" type="ORF">Cpir12675_005676</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000207">
        <property type="protein sequence ID" value="KAL1889698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00499">
        <property type="entry name" value="Ribosomal_eL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001380">
        <property type="entry name" value="Ribosomal_eL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018256">
        <property type="entry name" value="Ribosomal_eL13_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11722:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01294">
        <property type="entry name" value="Ribosomal_L13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01104">
        <property type="entry name" value="RIBOSOMAL_L13E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1889698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="201" mass="22757" checksum="91A7839D290EF8D5" modified="2025-10-08" version="1">MAIKHNQKIISNHFRKDWQRRVRVHFDQAGKKASRRVARQTKAAAVAPRPLGLLRPVVRCPTIKYNRRLRAGRGFSLVELKAVGLSARYARTIGISVDPRRQNLSEESLAKNVEILQDYKKRLIVLPNSEVDISKVDIKTKNTHNIALVDATTKEIKISEIPAPVEGGAYRKLRLVRSEARLLGKREKRAKDKADAEAAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPM7</accession>
    <name>A0ABR3YPM7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">D-aminoacyl-tRNA deacylase</fullName>
            <ecNumber evidence="2 6">3.1.1.96</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">DTD1</name>
        <name evidence="7" type="ORF">Cpir12675_005456</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a D-aminoacyl-tRNA + H2O = a tRNA + a D-alpha-amino acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13953"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:10124"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59871"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:79333"/>
            <dbReference type="EC" id="3.1.1.96"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>glycyl-tRNA(Ala) + H2O = tRNA(Ala) + glycine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53744"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:13640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="EC" id="3.1.1.96"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the DTD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.96" evidence="2 6"/>
    <dbReference type="EMBL" id="JAWDJO010000187">
        <property type="protein sequence ID" value="KAL1890286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.80.10">
        <property type="entry name" value="D-tyrosyl-tRNA(Tyr) deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00518">
        <property type="entry name" value="Deacylase_Dtd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003732">
        <property type="entry name" value="Daa-tRNA_deacyls_DTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023509">
        <property type="entry name" value="DTD-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00256">
        <property type="entry name" value="D-aminoacyl-tRNA deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10472:SF5">
        <property type="entry name" value="D-AMINOACYL-TRNA DEACYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10472">
        <property type="entry name" value="D-TYROSYL-TRNA TYR DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02580">
        <property type="entry name" value="Tyr_Deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69500">
        <property type="entry name" value="DTD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1890286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="160" mass="17602" checksum="50CB305C69E05E88" modified="2025-10-08" version="1">MKAILQRVLSASVTVDQVKISEIGKGILVFAAIAPDDTEKDAETMANKILKFKLWDDEEAGTRWKKNVQDIGGEVLCVSQFTLLAKTTKGTKPDFHGACPPEAASKLYHYFLQKVKDGYAEGKVKNGKFQAMMEVGLVNDGPVTIELNVGNDKKEARDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPN9</accession>
    <name>A0ABR3YPN9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CHY-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_005620</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000202">
        <property type="protein sequence ID" value="KAL1889852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052604">
        <property type="entry name" value="Mito_Tim_assembly_helper"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008913">
        <property type="entry name" value="Znf_CHY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037274">
        <property type="entry name" value="Znf_CHY_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28082:SF2">
        <property type="entry name" value="CHY-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28082">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05495">
        <property type="entry name" value="zf-CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161219">
        <property type="entry name" value="CHY zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51266">
        <property type="entry name" value="ZF_CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CHY-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1889852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="122" mass="13987" checksum="00A8D0EEEFDF49A4" modified="2025-10-08" version="1">MCKHILNAQVSIRAPCCRRWFDCAECHAEAEAHPIRQQSDMTFACKKCKKCFRKDAQEFEEADEYCPHCDNHYVLKAVMPKAALQVEGEDARVDARMLKDERVKGKGDITIFDPQPEADRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPQ5</accession>
    <name>A0ABR3YPQ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Manganese/iron superoxide dismutase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005451</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000187">
        <property type="protein sequence ID" value="KAL1890281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="entry name" value="Iron/manganese superoxide dismutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43595">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN S26, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43595:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Manganese/iron superoxide dismutase C-terminal" evidence="2">
        <location>
            <begin position="140"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Manganese/iron superoxide dismutase C-terminal" evidence="2">
        <location>
            <begin position="239"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="303" mass="33880" checksum="3300393282D8694D" modified="2025-10-08" version="1">MFRSSLRIPRAASLLPRQLAAARPAALLAATRARAMHSTSEVSAMHRVPKLDYAIENGISEFLSPDALDIAWTRYMSMTLEHLSNVVYDTEFADKEVKNIVTMTARDPETAHIFNYASAAHNNHIFFQMLDNNPAEMPIKLQTDLQMSFGTIDNLRREMIGTALAMFGPGFVWLVKTAMNEYRVMSTYLAGSPYPTAHWRAQTMDMNTLGANNSASSFIESTQTRAPSAKSSVPPGGVAVTPLLCLNTWEHVWLTDYGIEGKKQYSMNWWHKINWTKVEYLAGTVRVASEPTDPDNLRKSATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR00</accession>
    <name>A0ABR3YR00_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Bicarbonate transporter-like transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_005253</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000173">
        <property type="protein sequence ID" value="KAL1890798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.570">
        <property type="entry name" value="Helical hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011531">
        <property type="entry name" value="HCO3_transpt-like_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003020">
        <property type="entry name" value="HCO3_transpt_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11453">
        <property type="entry name" value="ANION EXCHANGE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11453:SF82">
        <property type="entry name" value="BORON TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00955">
        <property type="entry name" value="HCO3_cotransp"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="93"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="333"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="491"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="Bicarbonate transporter-like transmembrane" evidence="6">
        <location>
            <begin position="5"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="Bicarbonate transporter-like transmembrane" evidence="6">
        <location>
            <begin position="60"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="Bicarbonate transporter-like transmembrane" evidence="6">
        <location>
            <begin position="203"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1890798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="564" mass="61229" checksum="725769F5154D2ECF" modified="2025-10-08" version="1">MKFALCQGIVRDLRRRIPFYASDWSDAWDYRVVPATVYMFFAKCVSVPDSLMTQDIDGLCAVLIPLLSSILPALAFSLDMFASTDHHYGVTEVLLASVLGAGIFSLFACQPLVIVGVTGPITVFNYTVYDIMHGSDVDYMTFMCWVGLWSAVLHTVLAVTNSCNLLRYVTRFPCDIFGFYVACIYIQKGVQVLARLDASSPTEGEAFYLSIALALLVFLVAYAAAKVGESPLFLHAVRVFLADYGTPLTLVFFTGFVHIGRMRSVDVETLPTGAAFEPTGRSGWIVNPRNISVSDAFLALPFAVLLTILFWFDHNVSSLIAQGTEFPLRKPAGFHWDLFLLGITTGLAGLLGIPFPNGLIPQAPYHTKSLCVTSLSDPTSSASPALFDAVDDEKPRATLVVTHVVEQRVSNLAQGLLTLVAMTGPLLDVLHLIPHGVLAGLFFVMGVQALEGNGITEKVIFLAQDRQLTPKTHPLRACVRPGSHGIMRNRAIWLFVAIELVGFGATFAITQTIAAVGFPVFIMLLIPVRTLLLPRVFTPEELAALDGPAASPFTMESAGGIHGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR23</accession>
    <name>A0ABR3YR23_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nucleoporin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_005429</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the non-repetitive/WGA-negative nucleoporin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000185">
        <property type="protein sequence ID" value="KAL1890382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1880">
        <property type="entry name" value="Nucleoporin, helical C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.440">
        <property type="entry name" value="Nucleoporin, helical domain, central subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.450">
        <property type="entry name" value="Nucleoporin, helical domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007187">
        <property type="entry name" value="Nucleoporin_Nup133/Nup155_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014908">
        <property type="entry name" value="Nucleoporin_Nup133/Nup155_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004870">
        <property type="entry name" value="Nucleoporin_Nup155"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042533">
        <property type="entry name" value="Nucleoporin_Nup155_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042537">
        <property type="entry name" value="Nucleoporin_Nup155_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042538">
        <property type="entry name" value="Nucleoporin_Nup155_C_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10350">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10350:SF6">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03177">
        <property type="entry name" value="Nucleoporin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08801">
        <property type="entry name" value="Nucleoporin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin Nup133/Nup155-like N-terminal" evidence="6">
        <location>
            <begin position="145"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin Nup133/Nup155-like C-terminal" evidence="5">
        <location>
            <begin position="683"/>
            <end position="1360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1890382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1411" mass="155619" checksum="30BBEE67225E5B8C" modified="2025-10-08" version="1">MAFPYTTPARPLPGAFLSTPAMGGKLQSKTPDNLRRRLFVDDKAKTDLLTTGAISGSSVRSTLDAAPEAKLSFTTSPAVNITNGLVAGSLVPAPEELSPAARAAKQINQILQADQNFPDLDSYCRQGASSDYNVSYIESPWAPFQKTQMYPIPEEVFNHYDSSNLQTMMGLFAEINHAWVVIDNAIFLWDYTQSTPELIGFEDQPHSIQAVALVAPKPGIFVATITHILVVATSSEMILLGVSAETSAAGTKTASLYQTKMTLPLRGLDVRLITGSSNGRIFFGGATDIDIYELYYQQEERWFSNRCGKINHTNPGWAAVVTMQTGLFGTKAPEHLVDLAIDDSRNLLYSLSSRSTIRTYHMEAPNKLSKVIEKEKTHCLRDITHMINASSLLNDRMSIVSISPISSTEAAKLHLMALTSTGCRLFLSATNAASYMASAISNLAPQSMQVQFIKFPPPGKSSRFYPSGVDLDSTTLSTSRMGARYAPGYFLDFVAKETHPNEDLLFVSAPESGRIKATPATTPLKYYEQASWIEIGGKVEAVGLVSQPFAAASTPVGFGNELAVQFDQPHNEFAILTNTGIHVVRRRKLVDIFAAAVRGSVGNEGLEMETKKFIKLYGNVETISAALAVACGQGSDSTRPGVPRAIDQSTEDGARKVFVDYGGHPIMTEADGTPLSTASAVLSARHDGLSLYLGRLVRSLWKSTIVSVSTSPAGSPLVKSTIPSTKLQSVQSSLERLRKFLDANRPFIQGLSGPSDLQRASSKQEEMALQAEHQALHALEKLMESISEGISFVQMLFDERVSDIYARLDDGTRAALKVLTYEKLFSDATGKDVAKILVKAIVNRNIDNGSNVETVADALRRRCGSFCSPDDAVIFKAQEQLKRASEQPISSTGSLSLLLESLKLFERVAANLSFSNLELAVAQYIEMRYYAGAIRLCLAVAREKDRGNSVLSWINEGKPATDSRADVYAQRKKCYDLIHSILQQIDVESGSEPETIDGRPTLTALKRMEAYEIVNSSSDEVFHFDLYEWYISQGWTNRLLAIDSPHIVTFLKNLAATDAAHSELLCRFYTHRDRFYEAAQVQYQLSQSDFNLGIKDRIVLLSHAKSNANVPSPGIDRQEKQCLEHEITEQLEIAHIQDDVLERLRSDPRVPADRLVEAEEILDNKICSLNLLFNDYSDQAGYYDLCLLIYHAAEYRNATTILSTWQGLIMQTHEDAIVRMDEGVTNAPLPYESVTTRIQEIAHRTSCDSLIFPVSQLLPELCQYAVVNQQDASIGADPVWPVQLFLSIGISHEMITRILEHVFDTQDFGFTGSNRPRLIELIVYVVDGWVREVRRRGVSNGNGRGMSSLGHSIRDLLERCETELPPPGHGSNPGGKDINEVRRQLRNTQRDVTNILERAMTSGMTGSMRFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRY0</accession>
    <name>A0ABR3YRY0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005123</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000163">
        <property type="protein sequence ID" value="KAL1891115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050228">
        <property type="entry name" value="Carboxylesterase_BioH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194">
        <property type="entry name" value="HYDROLASE ALPHA/BETA FOLD FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194:SF2">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN LPX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="25"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="290" mass="30990" checksum="F5B903C9CA3DAF38" modified="2025-10-08" version="1">MTSTFALASGQAISYRLDPVNPHTPVVVLANPLCAPFTIWDNIVPLINAAGFSVLRYNQPGHGDSSTPSPPSECTFDSISAAVFELLQQLKIRDIHAWVGVSMGAATGIFFVSKYPGVAKKIVICGTTSLSPVNAGQPNIFASRVAAAREAGSLEATVSGTMDRWFGEKFLKIHEAEAARIKALMLTSTLDGFEACCAALSSKTFDLRPLFKNLGSCVSDALLLAGQNDGDLPEQMADMRDQIQNGFSGEGRNEVVLEVIKNAGHVPFIDAADDFVQLVVPFLQQSRTQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS17</accession>
    <name>A0ABR3YS17_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Mannosyltransferase</fullName>
            <ecNumber evidence="11">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SMP3</name>
        <name evidence="12" type="ORF">Cpir12675_005076</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the glycosyltransferase 22 family. PIGZ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="11"/>
    <dbReference type="EMBL" id="JAWDJO010000161">
        <property type="protein sequence ID" value="KAL1891141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005599">
        <property type="entry name" value="GPI_mannosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760:SF3">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03901">
        <property type="entry name" value="Glyco_transf_22"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 11 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1891141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="448" mass="51810" checksum="0404350C1462F12D" modified="2025-10-08" version="1">MMREIFHYPVRKTWEFVGDHPIRSVFPLWPVYGLPMQLLQWLWVGNGHDGEITPIAVLWTLRVLMFVTSLVLEDFAIYELMKQDSTQHQNRAWLLVASSYVTWTYQTHTFSNSIETLVVCWCMVLISRIKRDPHISKPGSLAALVFSGLATAFLAIALDTAFYTPRAITWLDLFRNPIITPLNNLRYNMNPENLAHHGLHPWYQHLFGNLPILIGPAVLLIFTRARMSLRHSFRLYSALSGIIMLSFFKHQEARFLLPVVPLILSSIQLPENKKIWRYWVASWVIFNSIFGILMGTYHQGGIIPAQVFMSQQPDATHAVWWKTYMPPIWLLNGKNEVLTTEDVMSLPGTELLSRITEIATCDTPADRRNNEYRKEKTGSYLVAPASATWIDPFLPNKGLDGLRFREVWRYSKHLNLDDLDFAEDGVWNTLRRVVGRRGLVIWRVTKSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSB2</accession>
    <name>A0ABR3YSB2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Replication factor C (RF-C) subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RFC5</name>
        <name evidence="3" type="ORF">Cpir12675_005038</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000158">
        <property type="protein sequence ID" value="KAL1891248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050238">
        <property type="entry name" value="DNA_Rep/Repair_Clamp_Loader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669">
        <property type="entry name" value="REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669:SF1">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13177">
        <property type="entry name" value="DNA_pol3_delta2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22534">
        <property type="entry name" value="RFC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="34"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="352" mass="39689" checksum="BA2779589CB2CD0E" modified="2025-10-08" version="1">MSLIVDKHRPRTLDGLTYHPELSSRLRSLAQSGDFPHLLVYGPSGAGKKTRIVATLKELYGPGVEKIKIDARVFQTSSNRKLEFNIVASVYHLEITPSDVGNYDRVVIQDLLKEVAQTQQVDQGAKQKFKVVVINEADQLTRDAQAALRRTMEKYSPNLRLILLANSTANIIAPIRSRTLLVRVAAPSHEDICSVLAASAQRESWPVLPGLYKRIARESGRNLRRALLMYEAVHAQSDNITDTTPIPPLDWESLISQISKQIMEEHTPQRILAVRAQLYDLLSHCIPATTILKSLTFKLVAQIDDALKADVIRWSAFYEHRIKTGTKVIFHLEAFVAKFMRILETYLMDMGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT25</accession>
    <name>A0ABR3YT25_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">3-isopropylmalate dehydrogenase</fullName>
            <ecNumber evidence="4 13">1.1.1.85</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">LEU2</name>
        <name evidence="15" type="ORF">Cpir12675_004962</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>(2R,3S)-3-isopropylmalate + NAD(+) = 4-methyl-2-oxopentanoate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:32271"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.85"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="13">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="13">Binds 1 Mg(2+) or Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="13">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 13">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.85" evidence="4 13"/>
    <dbReference type="EMBL" id="JAWDJO010000154">
        <property type="protein sequence ID" value="KAL1891451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003862">
        <property type="term" value="F:3-isopropylmalate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004429">
        <property type="entry name" value="Isopropylmalate_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00169">
        <property type="entry name" value="leuB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42979">
        <property type="entry name" value="3-ISOPROPYLMALATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42979:SF1">
        <property type="entry name" value="3-ISOPROPYLMALATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11 13" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="5 13" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 13" id="KW-0520">NAD</keyword>
    <keyword evidence="9 12 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="14">
        <location>
            <begin position="5"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1891451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="364" mass="38682" checksum="03FAC0C377CB2053" modified="2025-10-08" version="1">MSEFNIVVFGGDHSGPECVAEGVKVLKALEAARPIKFNLQNHLMGGCSIDAHGTPLTDEALNAAKAADAVLLGAIGGPEWGTGKVRPEQGILRIRKEMCTYGNLRPCSFASESLVDFSPLKADVCRGTDMMIVRELTGGIYFGERKEDEGDGLAWDTEPYSRAEVERIARLAGFLALRRGDKTVWSLDKANVLATSRLWRKVITEVFEKEFPTLKLEHQLIDSAAMILVKNPRALNGVVVTSNLFGDIISDEASVIPGSIGLLPSASLSGIPDGKSKCNGIYEPIHGSAPDISGKGIVNPIGTILSVAMMLRFSLNLPEEAAAVEEAVKRAIDGGARTKDLGGSVGTAAMGDAIVAELNKILAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTI1</accession>
    <name>A0ABR3YTI1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">pectinesterase</fullName>
            <ecNumber evidence="3">3.1.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_004874</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Glycan metabolism; pectin degradation; 2-dehydro-3-deoxy-D-gluconate from pectin: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pectinesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.11" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000149">
        <property type="protein sequence ID" value="KAL1891654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000070">
        <property type="entry name" value="Pectinesterase_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321">
        <property type="entry name" value="ACYL-COA THIOESTER HYDROLASE YBHC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321:SF58">
        <property type="entry name" value="METHYLESTERASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01095">
        <property type="entry name" value="Pectinesterase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0063">Aspartyl esterase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045364131" description="pectinesterase" evidence="7">
        <location>
            <begin position="23"/>
            <end position="2427"/>
        </location>
    </feature>
    <feature type="domain" description="Pectinesterase catalytic" evidence="8">
        <location>
            <begin position="985"/>
            <end position="1282"/>
        </location>
    </feature>
    <feature type="domain" description="Pectinesterase catalytic" evidence="8">
        <location>
            <begin position="1332"/>
            <end position="1618"/>
        </location>
    </feature>
    <feature type="domain" description="Pectinesterase catalytic" evidence="8">
        <location>
            <begin position="1696"/>
            <end position="1982"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="28"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="265"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="354"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="450"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="83"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="98"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="154"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="354"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="453"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="2427" mass="251353" checksum="AB8DD783DD423E95" modified="2025-10-08" version="1">MVRVSALALVLSLSGFIADVQAAPHGTEPILDSRGEQRREVLSSSCKAKPSSPPVHDGVTRSSSNSSNSGRNYGDNGNGKMHGNNSPNRGKGHQSQTNKEHSGSSHRYDNGRGPTRSQGPGNSRFPASNKGPGSSKGPKVSYGNSHGKDNGKGYNNGNGNGSGHGVGVSHFTTTVTTATSSHSASSSSNNPGKISDSSVLVSSSSVTSPAPAMTLTSTIASSRPEASSLSSVIFQAVTSASSSASVPTQPSSYIVTLAPSFSNSSMAMSPSHPNSTTTTSLLNSTTTLSSSPTLSSFVSLTYTSLSASISSFGNSATPFVTLSETLTTSLEAPSSDFSSIFTISITSTDSSTINPLPTEAATTSTEAITESTDDGLVDSESSSGRETLVATDTVESTSTVYGSDITETSAVKTTVTTSSLADIETSTTETLSAISGSVTETTPAAISTSVGIETSATETSTTSYPSNSSTTASSVDTSTTDISSVIYTLVNNTVTPGSGGSVSISTEDFTTSSSAITESSMNSDPSSTPYDITANPTAALYTTSVAANTSIADNTSVAANTANTAVAMTTSAALFTTDNGLTSTSVTLSTETSSSSTLAATTTSVATVPSSITTTSSTVYSTSSTSSGTAVTVAQDGSAQFTAINQAIAYAQASGIPTVSVLAGTYTEAVTISSTASITIAGPTAASYADNKVTISQPGRVVTYNAAARVAWRNVKIASTDATAASTAGGAIYLRGGKNAFYGCSLVCAGAGCLTGNYAAALVTDSYLEASDKLMYAYPSVYLFRTRVVPTASNALVVYNQGATINSVIYNSTIVLDSSEIVQKSGATNTNVFLAAANSAGGSVALLRNTSIASFVAASGVHVDSKTQATGNFYTEFLTSGAGAYKSNSAARAAYVTSAIDASALGNYELKAFFAGVTPSVASTDVNWIDADIVAAISASNSQQAIQATATTTTTTISSTSTSTLITTTTAATTTTTTVPSTFTVAATPTAGQYGSVQSAVLALPNDGAAYTIYILAGTYTEQLSINRTGMVTLRGETTYANDYTQNKVRIEFSRGYLTSLSRNEETPVLYSRKTDGSGLSLYNIDFVNTYPQTSNTAALAADFYGKKMAAYGCSFVGFQDTLLANQGTQVFSNCYIEGSVDFIWGYSKAFFHQCYIASNTAKGASITAQNRPSSAWAGGFVFDSCYVTYTAAYGTTMGQTYLGRPWSSYAVAVFRNSYLDKHINAAGWSIWSTSAPQTDNVFFGEFNNTGPGAWTSTTERATFATNMTVEQSSTYDLGTFLGDTSWVDNTAYGYVPSYPLAAETSTTETETTKTFTWAVPTNGTEPPVGAVLVSVDGSVEGSFSNLTFAIASLPSDSTPQAIFIYPGTYTEQVPSIKRSGPVMLIGYTTATPGSSYSSNTVTLTQARGLSVSPLPTGHSNSETATIATGSTQIALYNIAIINSDNLDGAQKSYVTLAASLYGTHISMYGCSMIGWQDTLLTGQTNGYMYFESSYISGAIDFIWGYSAAYFKGCTIAAKQAKSCITAHNRASSSAIGAYVFDQCLFTAATTEGFSVSSLSQSVYLGRPYNSYARVAVKQSYLGSIIAPAGWKQWSTTSPNLEYVTFAEFNNTGPGNWENNAASREAFGSATLLESDSYPLSGVMDSTSWIDLTRWDSIQTPQETDSSTTVTPEITTYNGTTPPTGAFIVSKTPIENTVTYSTIQEALNALPSSSKTTATVFIYPGSYYEQLTLNKSGTTVFLGYSERPEDYSANTVTINFDHGIDTQADQSNSDGATVYATGNYFKAQNINFANTYGTATNYASLGFAVRSSKYASLYQCSVVGSQDALLINGNLFAANSYIEGTIDMIWGSGRGYFLNSTIAPSRDDISLTADKRASNTTAGGFVFDKCTVTPAKGAKYSEISLGRPWNNLARVAYVESYLDSCVQASGWEQWSKSSPQTDGVLFGEYANSGPGADTSARAAFATQLSDSEVAQFELATFFGDASWVDTTLLTSSPFVAGNATITKVVTVTQTVTVSGVTTTTATISGSHTLSVTVTSTVSSKTTVTAEPTTTVTKVEKTTITNVETSSIPGKTTTVVATVISDIGTTVTPAPKTVTSTLKSTTTVTSTSVTTLKASTIKSTTTISSVVTTTAKPVSTTVTVFSTVYATSTAKQSTISTTSTLFKTVGSTDATTTSLKAKTVSATVTTTSVKTTKKTTTLSCIPTLARRSFDEVAEEDLAKRAVTEYRTSTITVTSNALATSTVFKTGSATTITVKATVTVVSTVTLKAATPTVIVTSTATKASTVKVTGSDVTVSSTTTKTTGKATTLDPVTSTSTVTAMATTTTVVKSTVTSAAVTSIATTSVVSTVTIPASTSTKTVTSVSTIKTTVTPTPVTKVTVKTVTVSLVPSTTVTLQSTVTKTKTVEVKSTITQWATKTAKNAPTCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV14</accession>
    <name>A0ABR3YV14_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein YIP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_004779</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Golgi apparatus membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the YIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000144">
        <property type="protein sequence ID" value="KAL1891890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045231">
        <property type="entry name" value="Yip1/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006977">
        <property type="entry name" value="Yip1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21236">
        <property type="entry name" value="GOLGI MEMBRANE PROTEIN YIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21236:SF1">
        <property type="entry name" value="PROTEIN YIPF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04893">
        <property type="entry name" value="Yip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="Yip1" evidence="8">
        <location>
            <begin position="173"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="43"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="310" mass="33526" checksum="42FBCF10D8DEFC09" modified="2025-10-08" version="1">MTPPNSNKKLYEEPTIDDDDMIDPDDADLNDFDDPLDTRPLNGPSSSSGAGASSSRSGTAPTRSGSSATESYLTSRIPGEDRHAAQNTIDESVWATLRRDLLAIWSKMQEVLWPRYILGGSMFESPEGLRGAYANLREAGIAGAREEFASLAGRVMDTEALVSTNHMTPGLRDWDLWGPLIFCLALSVLLSIHARPEQRDAVFSGIFAMVWTGEAVVTLQIRLLGGSISFAQSVCVIGYTLFPLVIAALLSAFRLYWAARIPIYAVLVLWSMAAGISILAGSGVVKNRVALAVYPLVVFYIGIGCLCFIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVG4</accession>
    <name>A0ABR3YVG4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Rho GTPase protein rac1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RAC1</name>
        <name evidence="4" type="ORF">Cpir12675_004619</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000135">
        <property type="protein sequence ID" value="KAL1892263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0488">Methylation</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="199" mass="22155" checksum="A03C4E8BCAE5E3F2" modified="2025-10-08" version="1">MAQPGVQSLKCVVTGDGAVGKTCLLISYTTNAFPGEYVPTVFDNYSASVMVDGKPISLGLWDTAGQEDYDRLRPLSYPQSDVFLICFSIVSPPSFDNVKAKWYPEIGHHAPNIPIILVGTKLDLRDDKDTLEQMMQKRMEPVSYDQALICARDIKARKYLECSALTQRNLKSVFDEAIRAVLSPRPVNVKPKKPKCTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW40</accession>
    <name>A0ABR3YW40_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_004603</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000134">
        <property type="protein sequence ID" value="KAL1892280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="231"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="265"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="438" mass="49076" checksum="B6F6077619039C33" modified="2025-10-08" version="1">MHLIHKALSHARPATSWCFDAVPRPKKNTPRPRSLADAFPVELILAIAEFLDISGLNGLMRSSRCFYNILNTYIYRRDAQFRNDAIFFSVLRTSLDERLHWSTILRSLRFGGNVNALHLMVGNEIGIATLRPIHLSIIMRNTPHNIDRLLCYGALPESPALDVQNLSSFLLPKSIYFHSSVLQKFNVAKKVPTSIIAMCSILDPSDSANVRMFDALLDAGMPRDVHVPGLGHTTILHVAAHLGLTQLVEALLTRHGFDINGQDARGKTPLHWAAHRSVNRTGRTVRYLLSNRAQPNISDSWGWTALHTIAIWGRISKFSLDIMTMLLLAGADPNLGTPLENSALGLVINASILLESSRAYRVKAVNLLLDFGAEFSDRQILDLFESECKRTAKCETVDRQHLDNFDRLITRLMWPEDPSEDDLMEFASSNRFPGSPQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW87</accession>
    <name>A0ABR3YW87_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">mRNA stability protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_004916</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the endosulfine family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000151">
        <property type="protein sequence ID" value="KAL1891574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006760">
        <property type="entry name" value="Endosulphine"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10358">
        <property type="entry name" value="ENDOSULFINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10358:SF6">
        <property type="entry name" value="ENDOSULFINE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04667">
        <property type="entry name" value="Endosulfine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="56"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="172"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="182" mass="19187" checksum="12AE0CAC47FDDBD5" modified="2025-10-08" version="1">MNPLQKNKVDIKSLSPEEQRLFRLYGKLPSRSDHFAKHLKERKYFDSGDYALSKAGKADSVDAGSVGSQHPQPENIPHRESVNGSNAATTSAGGSAAAAGIAGAPGVTPLKHAGINGVTPAAASPAKEASFLNRETKPETDGEQQEEQEGEKEEEPEAEASSTTPNAAEQMGGQSQELPIRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWA2</accession>
    <name>A0ABR3YWA2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_004898</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Sodium-phosphate symporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000150">
        <property type="protein sequence ID" value="KAL1891589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101:SF57">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="446"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="496"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="582"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="296"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="613" mass="65762" checksum="BBB137975E8A1643" modified="2025-10-08" version="1">MVLHEYTYVFAIGTCFALLEAYNNGANDVANAWATSVSSRSVSYRQAMILCIIFEMTGALAVGARTASTIKNGIIPVSAFNGNAGVQLLAFACASAGASTWVMWCTRHNAHVSSTYSLISSLAGVGIATVGVSEVQWGWNGGQGLGAIFAGLGMAPAISACFAAAIFMLVKIFVHMRQNSVQWAVWTSPFFFLIAGTVCTLSIVYKGSPRLGLTDKPPGWIAGVTLGTGFGLALLSALFFLPFVHSRVIKKDYTLKWWHVFYGPLLFKRSAPADAVRAKVPDYAVVQHDSGDLQVTPANVPSLAPSDSSEPNSDKILSSPAIDPMAATPAATEKALVRSEATHETYQKMLRDAEEHHHANLRKGEGPLGWAMRTLHENPMGAGSLHETHNLIALVRRIPAMIVVACLYGTAYDIHTAQVGIEGTPEGRRMERVYDSATKYPNEVEYLYSFVQVITACTASFAHGANDVGNAVSVWAVMYSAWNTGEAVGSKAEVPLWQIAVIALTICIGFITYGYNIMKVMGNKITYHSPSRGSSMEMGASITVLLFSQYKLPVSTSMCITGATVGVGLCNGTLKAVNWKRVFLLVFSWIMTIPIAGLIGGCLMGLALNTPHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWY8</accession>
    <name>A0ABR3YWY8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pre-mRNA-splicing factor ini1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ini1</name>
        <name evidence="2" type="ORF">Cpir12675_004559</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PHF5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000132">
        <property type="protein sequence ID" value="KAL1892406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005345">
        <property type="entry name" value="PHF5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13120">
        <property type="entry name" value="PHD FINGER-LIKE DOMAIN-CONTAINING PROTEIN 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03660">
        <property type="entry name" value="PHF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016468">
        <property type="entry name" value="PHF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="110" mass="12415" checksum="65B92F43A00F40CB" modified="2025-10-08" version="1">MSRHHPDLVMCRKQPGIAIGRVCEKCDGKCPVCDSYVRPTTLVRICDECSFGNYQNKCVVCGGEGISDAFYCFECTRVEKDRDGCPKIINLGSSRTDLFYQKKTNRSQAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXR1</accession>
    <name>A0ABR3YXR1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WD repeat-containing protein C3H5.08c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_004366</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000121">
        <property type="protein sequence ID" value="KAL1892832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040324">
        <property type="entry name" value="WDR44/Dgr2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14221">
        <property type="entry name" value="WD REPEAT DOMAIN 44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14221:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="308"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="377"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="417"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="104"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="651"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="788"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="941"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="18"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="113"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="654"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="819"/>
            <end position="828"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1892832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1098" mass="117825" checksum="997B3D77A5370BA1" modified="2025-10-08" version="1">MSTRADTRRTSLVFPFGSKDKDKDKDREGERASRSGLARSNTVVLAKPDDKRGTVGAGAGSSSSAATSGASVAVRDAPSVLTASVTNSGLDPLSEHILQRTSTNDLHTHSRSHSGSAARPQSISFSSHHISRLSRNPAYSKPPSLGSVVANPDPATRSQASGTGDGIISAVTATAAPITSSGVFTETSKEKKRSLSFFNRLGMIGNRRKEDSVGDGETSDSGDHRIEGARILMSPDASGFIPHHKEPAKYQRTKSNCKRHKEFGNLFLAQEISAARSPIGSNDGGISASKTGATVAASPAVKPARPELTSHDGAVWCMEFSQDGKYLAAAGQDGIVRVYAVLASPEDRYSEEDSIPDPSHGERLRAPVFRSRPVREFSGHEGEVLDLTWSKNGFLLSSSMDKTVRLWHLDYRESLCVFKHRDFVTSISFHPRDDRFFLAGSLDCILRLWSIPDKAVAFSATVPDMITAVSFSPDGQTSIVGMLHGLCMFFETEGLKLQKEMHVRSSRGRNAKGSKITGIKTLETPSYNDGGVKILITSNDSRIRQYNMRDKSLDIKLKGHENVSSQIHSRLSEDGQFVICGSEDKRVFIWPTNLNEGDAKDKRPLEYFEAHDDVVTVAMFAPTSTRRLVGSSDDPIYDLCNPPPIRLMSKEEASASQTSLSQPSSTKRIKPEESPAYIARSAHNDGNIIVSSDKSGIIRVWRQDCAATKRRHENLSAQRLTTLTRTGSIMTRTSFASSSPYSRRGSVSHLGAAAAASARGAGAVGEGSAGKAVQLNSDIIDSWRQGVVDSPGALGSTGPGHAVEPPRTPTNLGHLGQAQALTPPSSDKAQPYESAIDDSPPYRRGAVPGPELSPPIVELSDDGETPEKQTETEGQEGFIESFLNRWRGRSASTVSSVAAAAMAAVTNGNTRTNSTENINVPAGADEARQSSTAVTFAIEPLRSPTPTTPTVGVQRPSLEENGRFDDDDLTGTTPTPSNIHLLSPKARAKRRHSIGPRALTDAYIDRTSSKAHDLALPSLDPRPKSAHGAESGAVPAIAIINENAELQQEDQDETDGNETLGSSCAGCGRRDFYMRKIGGRPRLLCSGCGMLVSESQQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYQ9</accession>
    <name>A0ABR3YYQ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_004275</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000117">
        <property type="protein sequence ID" value="KAL1893084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF1">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="240"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="319"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="343"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="429"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="458"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="863"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="903"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="984"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1089"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="255"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="520"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="866"/>
            <end position="1152"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="1194"/>
            <end position="1430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="119"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1165"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="120"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="137"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="179"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1893084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1434" mass="157931" checksum="1AF0B721E66B036E" modified="2025-10-08" version="1">MDMSSDKLTKMAATVSPVSPLIVSPPTPTPSSADDAAAIRRVQTNNHLRASQSNPNSRKVSVASAVTNSSVETAFRGSVNSGKPSFWSVPESVRSLVGSSAHISEAPPTVASATAINGHARSEAARKKVGVDAETHSLANASPKSPSPTRRKATPLEWKPLQLGGCEMETSEHSQRPLLPKRRKLKKQQKISPESTSSDAEFQPPSESGITRSRRGGQLVYDITKFYTISTPNDPVRRELVSTIHAAVFHFIYLGAARFVLGYGTNKISLQITAAFRERHLESLLSHPLSIHDALPPGWTNNALTITTEYLQVGFESHLPLLLTTSSMIISAMVVAFVYNWKLASIIFAALVPMAVIYALSSSPIDRVMSTIKHINSRACEIVLEGVSIATTIIAFEAQKKVTSKYTNCLQQSSPFGDKITRLISMQQATFALIVFSTNSLAVYYGMRLYVNHEMSDIGTLVTVFGSMIIVVTSISLFNQPIQSLALAMDYASFLFDFIDIPSPKLDVSERSNVFDFGDIVFKDVSLSYASRPNVKALNNVNITIPQGKTTAIVGPQGAGKSSIVALIQRWYELDARPLHSPSLCNGKIFCGVSSLTDLDVRYWRSQIGIVARDSHFFDGTIQENIEYGLVGSGLEHASAEIKRELVEKACADALALDFISELPNGLQTKFKDCEPTLTIGQKQLIAIARAIIRSPKLLILDDVTNGLGGREETDVLRAMARAAKNQTTLKLAQHLKAAFDADKTIVLAGGSVVQTGSSFVELIQATDGPYAKLFFAQRLDPENQITIERPSTWWRRKSGLVPLMLEGFEFTENREWELNMRRGLDLMSSYADRSSATDTNQPSGLAGFCSVFFKDKGELWPWYYLLGVGSMVIGAASALQSYLFAQQIDNFFLESQILQERVGFWCLMLLATAGASSLGYLCSTWATTHLSFKLFEALRRECFSDFINQPVPFFDEVSNNSEILTAAITTDSDYLQRLLSSTVGTLMVLIFNTLGNISICLYFGWELTSIAMGTALPLVALSTFLRVRDNIHTKQFNTRGRDEATRFATETLAASRTIISLTIEKIIIRKYHSFLQAHNRRSCHRRMIAYMLLCLGDSLPLFWIAFVLWYGIRLIETHRYQMLEFLVILFSTIQQGMAIIQCLNTSSSIADAMTAAKRMISRKPKSSGSVSFEGDSNGMGRPDSEKGKGKFDVELLNVWLKYPKREVSVLTGLNIKINQGEVIAIIGATGSGKTSVLSLLERFYEPTRGMITANGVNIKHQKPEDYRRSVSIISQEPQLMSDTLRNNIVLGMPADTSEEKVYEAGRAAGIHDLASSLPEGYDTLLGCHGTILSTSQKVRVALARAIIRNPKLLLLDEVMCGLTNEEASALKETIDQVRENRSVVMATSRVDVAQPANMIYVILEGVVVEMGSHNQLMEKKNVYYYMSVAQALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ47</accession>
    <name>A0ABR3YZ47_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial distribution and morphology protein 12</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Mitochondrial inheritance component MDM12</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">MDM12_2</name>
        <name evidence="9" type="synonym">MDM12</name>
        <name evidence="12" type="ORF">Cpir12675_004261</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Mitochondrion outer membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Endoplasmic reticulum membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="9">The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the MDM12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000116">
        <property type="protein sequence ID" value="KAL1893115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21672">
        <property type="entry name" value="SMP_Mdm12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03104">
        <property type="entry name" value="Mdm12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027532">
        <property type="entry name" value="Mdm12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28204">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28204:SF1">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26544">
        <property type="entry name" value="Mdm12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="6" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 9" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SMP-LTD" evidence="11">
        <location>
            <begin position="1"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="64"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="168"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="234"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="69"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="115"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="188"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1893115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="434" mass="47023" checksum="E5B21F2871A4E65F" modified="2025-10-08" version="1">MSIDLNWDAITSGPEGDLLALRIRDFIHEKFQTVPLPRFLKSVKVHSFSFGDIAPELELKDITDPLPDFYEENPDVDDSESEKDEQDLVPDSEPDGRRRHTIGGRDAEERFRDGLSSNDSQYWRATTPGVPGGTSNMHYFQQTHLGASWSGAHTPLAAVAGAHLSGPWNSGSGGGQSTTGSSMHIAGTSYTSAKSPPGSNVPAGVHSRAPSIGSVTSAADEALLAEMRDARGTMVSTDEADVAVTSQAGSKRGGDEAANESETDSNSVPRYREPRPEDVQIVFRIRYAGDIRLLLTAEILLDYPMPSFVGIPVKLNVTGLTFDGVGVLAHIRRRVHFCFLSPEDALAAVGPDSAELGGALAANQSVTSLIGGAHREKKFGGLLQEIRVESEIGQRESGKQSLKNVGKVERFVLEQVRRIFEDEFVYPSFWTFLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ62</accession>
    <name>A0ABR3YZ62_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Long-chain fatty acid transporter fat1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">FAT1</name>
        <name evidence="7" type="ORF">Cpir12675_003977</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000104">
        <property type="protein sequence ID" value="KAL1893679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107:SF15">
        <property type="entry name" value="FATTY ACID TRANSPORT PROTEIN 3, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107">
        <property type="entry name" value="LONG-CHAIN FATTY ACID TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="5">
        <location>
            <begin position="67"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="6">
        <location>
            <begin position="501"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1893679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="629" mass="70384" checksum="4DD3073C47AE838B" modified="2025-10-08" version="1">MSAIAAAGLVGTAAYINARAGIWYDYHLVRSVIPSALRSFIRSRTNGLNQFYVLERWARSSSRASLPLIKFEGRDYTYAQTYAAALSYGTWLRESKGVKPGDIVAIDFQNSETFVFLWFGLWAIGAKPAFINYNLTAQPLAHCVRACKAKLVLADPLIQESFTESVMQSIPGAELVVVTPDLDTQIRATQGKRYPDQVRNEDDIKNIAMLIYTSGTTGLPKPAIISWGKATVSSNFCSRLLRLTEKDVFFTAMPMYHSSASLLGFLNVLEAGSTISISRKFSAKTFWDQVRQSDATVIHYVGETCRYLLGTPPQTDPETGELLDRKHKVHTAFGNGLRPDVWDKFKERFGIDYIAEWYASTEGPFAIWNLSRNSFTQGAIGRNGWIYNMLMSINVQVVEVDPLADQPWRHLKSGLCRKVKAGTPGELMFRLPSNDVESRFQGYYGNEDATNSKILRNVFSKGDAWFRTGDMVVWDNDGRVFFSDRIGDTFRWKSENVSTAEVGQIFGQHPVVHEANVYGVELPRHDGRCGCAAIVFTSDVKGQPSPEVLKSLADHAANTLPKYARPIFLRVMPEMEATSTFKQLKHGLRAQGVDPEKVDSGKMYWLKNGTYTPFTETDWTMMVSGGVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0N8</accession>
    <name>A0ABR3Z0N8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Hsp70 nucleotide exchange factor fes1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">FES1</name>
        <name evidence="6" type="ORF">Cpir12675_003793</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Functions as a nucleotide exchange factor (NEF) for Hsp70 chaperones which accelerates the release of ADP. Required for fully efficient Hsp70-mediated folding of proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FES1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000095">
        <property type="protein sequence ID" value="KAL1894151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050693">
        <property type="entry name" value="Hsp70_NEF-Inhibitors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013918">
        <property type="entry name" value="Nucleotide_exch_fac_Fes1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19316:SF18">
        <property type="entry name" value="HSP70-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19316">
        <property type="entry name" value="PROTEIN FOLDING REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08609">
        <property type="entry name" value="Fes1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13646">
        <property type="entry name" value="HEAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nucleotide exchange factor Fes1" evidence="5">
        <location>
            <begin position="7"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="4">
        <location>
            <begin position="133"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1894151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="206" mass="22681" checksum="34E14F255EBFA447" modified="2025-10-08" version="1">MNNDKNLNSLLKWSIENSGPEIPADKRTQLTPDIIASLMGGPSDAELMKAAIELVTSNDPEITVESKVTALDNFEQLIESLDNANNMANLGLWSPLLTILKSPEPELRRMAAWCVGTAVQNNASSQERMLACGGIPPLVEMALKEDEEKNVRKKAVYALSSSCRNYQPSMDVVLEELAKYGKTYEKINAENMDEVDSVILPLKEAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0Q0</accession>
    <name>A0ABR3Z0Q0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycerol-3-phosphate/dihydroxyacetone phosphate acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SCT1</name>
        <name evidence="4" type="ORF">Cpir12675_004028</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000106">
        <property type="protein sequence ID" value="KAL1893640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052744">
        <property type="entry name" value="GPAT/DAPAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31605">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31605:SF0">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="457"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="501"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="541"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="3">
        <location>
            <begin position="69"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="627"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="739"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="647"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="698"/>
            <end position="707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="785" mass="86565" checksum="A7E66329A1E60B67" modified="2025-10-08" version="1">MANEAHASPATLANAPQTVNGPEARKELYPMVNWKYDVFSWVMSILIDLFFREVHPRGSWKVPTTGPVLFVAAPHANQFVDGIVLQRTLRQEAGRRISLMIAQKSVHGFVGWGSRQTGSVPVGRAQDSAKPASGTIYLPDPIGDPALVRGIGTCFGEGEGVVGGLLFLPAGKKSASSSVDIAEIISPTELRLRRSFKGKLSMQQLTGRDDIDEDGKVTNLGICGSRPGYKGTKFKLAPHIDQTVVYHAVFDRLKSGGCVGIFPEGGSHDRTELLPLKAGVAIMALGALAEAPDCGLTIVPVGMNYFHAHKFRSRAVVEFGPPIEIPSKLVEMYKNNERRDAIGQLLDTIYQGLSSVTVSTPDYDTLMLIQAARRLYNPTGTFGKKLPLPVVVELNRRLAKGYERYKDDERIKQLMGAVQDYNRRLRYLNLRDHQVQYATMSLPTVVFTFFYRVLKLLVLSIAVMPGVVLFSPVFIATKVISMKKAKEALAGSSVKIQGNDVIATWKLLVALALTPTLYNFYSILVTVKVYQGRFWGYAPAWIPLWLVFIGAWVGLVGITFASLRFGEVGMDIFKSLRPLFLCLFPSSSYSMAHLRERRSELSVQVTDLINELGPEMFPDFGRRLHEAAEKQKKKKEQGQGGQRPKSADSGTSSPPSSHLASPETVHVLTQRDTQKSSRLLPRNDSFSNIGGHGMFSTRPPSRNRSRNSSVINFAGFTTLESKDGFDEATRKIHEAMKLRRRKSGGGAKMVIVSDDDDSEVEEQHPDELEGSSGDAEYDEARKKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0X7</accession>
    <name>A0ABR3Z0X7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">IRE1</name>
        <name evidence="17" type="ORF">Cpir12675_003760</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000094">
        <property type="protein sequence ID" value="KAL1894279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd09769">
        <property type="entry name" value="Luminal_IRE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10422">
        <property type="entry name" value="RNase_Ire1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13982">
        <property type="entry name" value="STKc_IRE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.180">
        <property type="entry name" value="KEN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045133">
        <property type="entry name" value="IRE1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010513">
        <property type="entry name" value="KEN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038357">
        <property type="entry name" value="KEN_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_b-propeller_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13954">
        <property type="entry name" value="IRE1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13954:SF6">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06479">
        <property type="entry name" value="Ribonuc_2-5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00580">
        <property type="entry name" value="PUG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51392">
        <property type="entry name" value="KEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6 14" id="KW-0732">Signal</keyword>
    <keyword evidence="4 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046699399" description="non-specific serine/threonine protein kinase" evidence="14">
        <location>
            <begin position="26"/>
            <end position="1271"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="842"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="domain" description="KEN" evidence="16">
        <location>
            <begin position="1136"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="26"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="651"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="45"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="654"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="671"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="757"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="870"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1894279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1271" mass="142194" checksum="394F977DAC659CEE" modified="2025-10-08" version="1">MQLRLGRYLIAFAVLPVAHTAIVDASPSQQTHHPEKHFQIANQDSNPSSHTNSRSNTNRNVDPNSSNPASAAAAAGYVPQYNQDAERVISRISQSYPSISDSNVRYRRDTAPLNNKKRATDEYQPKFTDYITSDDASALATLAPALAVRAPTPRLRSSPTPGSGVASQHLARSLGDWEVEDFVLMATVDGDLYAADRTTGRERWRLEVELPMVETIHYRANSSITDDDFNPVDHYLWAVEPSQDGSLYLWVPGENSLSGASIVQTGLTMRKLVEELAPYADAEQAVIYVGSKSTTLITLDAATGRVLKWFGESGTHVNEPESCLRPTAPFDREECASTGTIRLGRTEYTVAIQREDGKPVAMLKYREWGPNNFDQDLLQQYHASQTSFDNRYITSRHDGKVYGLDYGFDEATFHEPNTEPGSTVFSRKLPCPVARVFDLCRPRDVEAETNPELVVFPQPAPPAKNLREETARSTSIFLNKTQGGSWFALSGASYPMITNAPVALMAMDGLIEMPKSLEFDALCKALVGTHSLGSVSNGSKPKHHVHLIESGGPPQSKVENEYDYIDYIPPVDVVMKDPPTFIERVKSLPQTAARLVALSIIDLVSNPALFCLLIFALFYYQDDVRRWIRQRVKHGWLQDAGSSRKRIRKFLTPMEERDNPMESLNQEDRTPSATESSMTDRISKEISQVEANQVLDDDEIVDTLSPKVNKTVSLDMPEKNENKENGVSTPPVEPAGNSPNLSDNVVPSADSANAPPPKKKAHRGRRGGVKHKKKKRDSSQSREEDEASKAIDQNTKSVDDAVKGVLKITQQRETQVEPDVHSIMEDPENLNSPRLRMGQLEVDINNQLGTGSNGTLVFAGRFDGRDVAVKRMLIQFYDIASQETRLLRESDDHPNVIRYHSQQVRDGFLYIALERCAASLSDVVEKPHMFRQLADAGRQDIPSVLYQITNGIKHLHSLRIVHRDLKPQNILVNMGNDGKPRLLVSDFGLCKKLEGGQSSFGATTGRAAGTSGWRAPELLLDDDARDIMESSIHSGSGSVLVGDGLTPRRATRSIDIFSLGLVFYYVLTNGAHPFDCGDRYMREVNIRKGKYNLDQLEVLGEFRYEAEDLIKDMLNANPKQRPPAHEVLAHPFFWPPRKRLAFLADVSDHFEKEQRDPPSEALQELERHAPAITKGDFLRALPREFTESLGKQRKYTGSRLLDLLRALRNKKNHYEDMSDSLKRTVGSLPDGYLSFWTVKFPMLLLVCWDVVYCLGWDSTDRFREYYEPGSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z100</accession>
    <name>A0ABR3Z100_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">MET6</name>
        <name evidence="15" type="ORF">Cpir12675_003870</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (MetE route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the vitamin-B12 independent methionine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.14" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000099">
        <property type="protein sequence ID" value="KAL1893894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003871">
        <property type="term" value="F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03311">
        <property type="entry name" value="CIMS_C_terminal_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03312">
        <property type="entry name" value="CIMS_N_terminal_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00172">
        <property type="entry name" value="Meth_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013215">
        <property type="entry name" value="Cbl-indep_Met_Synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006276">
        <property type="entry name" value="Cobalamin-indep_Met_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002629">
        <property type="entry name" value="Met_Synth_C/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01371">
        <property type="entry name" value="met_syn_B12ind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003556">
        <property type="entry name" value="PRK05222.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30519">
        <property type="entry name" value="5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08267">
        <property type="entry name" value="Meth_synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01717">
        <property type="entry name" value="Meth_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000382">
        <property type="entry name" value="MeTrfase_B12_ind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="UROD/MetE-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="6 15" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Cobalamin-independent methionine synthase MetE N-terminal" evidence="14">
        <location>
            <begin position="4"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="Cobalamin-independent methionine synthase MetE C-terminal/archaeal" evidence="13">
        <location>
            <begin position="435"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="388"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1893894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="766" mass="85799" checksum="DA52784E5897E754" modified="2025-10-08" version="1">MVQSAVLGFPRMGVLRDLKKATEAYWGGKISQADLLAEAKRLRLAHWKIQKDAGVDIIPSNDFALYDQVLSHIQDFGAVPERYTVNNLNPVDQYFAMGRGHQKEGVDVPSLEMVKWFDSNYHYVKPTLQDNQTFKLSESPKAVNEYKEAKEAGIETRPVLVGPVSFLHLGKADRGQTVDPIDLLEKLLPVYEELLIQLKAAGAETVQIDEPVLVFDLPTKTKDAFKPAYEKFAALGDKIPKLVFTTYFGDIVHNLDLVPKSLYALHIDLVRNPEQLNEVLASLSPKTILSVGIVDGRNIWKTNLKKAIETAETAIQKLGKDRVIVATSSSLLHTPHTLASEKKLDPEVADWFSFASEKVVEIAVIAKAVTEGPAAVRELLEANAKSMNARATSKLTNDPAVKARQASIKPEDYNRKSEFPSRIAQQESKLKLPLFPTTTIGSFPQTKEIRAQRNKFTKGEITEAEYDKFIEAEIINCVKIQEELGLDVFVHGEPERNDMVQYFGERLKGYAFTTHAWVQSYGSRCVRPPIIVGDISRPAPMTVKESKFAVSVSSKPMKGMLTGPVTCLRWSFPRDDVHQSVQAEQLALALRDEVVDLEKAGIDVIQVDEPALREGLPLRSGKERDAYLGWAVNAFRLSTTGVEDSTQIHSHFCYSEFQDFFHAIAALDADVLSIENSKSDAKLLKVFVEEAYPRHIGPGVYDIHSPRVPSTQEIKDRIAEMLQFLKPEQLWIDPDCGLKTRQWKETKEALANMVEAAKTFRQQYAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2D9</accession>
    <name>A0ABR3Z2D9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DNA cross-link repair protein PSO2/SNM1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pso2</name>
        <name evidence="9" type="ORF">Cpir12675_003684</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000091">
        <property type="protein sequence ID" value="KAL1894455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16273">
        <property type="entry name" value="SNM1A-1C-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011084">
        <property type="entry name" value="DRMBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240:SF6">
        <property type="entry name" value="DNA CROSS-LINK REPAIR 1A PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240">
        <property type="entry name" value="DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07522">
        <property type="entry name" value="DRMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="8">
        <location>
            <begin position="413"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="DNA repair metallo-beta-lactamase" evidence="7">
        <location>
            <begin position="675"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="70"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="193"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="295"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="73"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="303"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="315"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="865" mass="95014" checksum="789C25371CB6FA67" modified="2025-10-08" version="1">MAKFDFGKRKKPAQTKISFQKLTPEEVEAANEKKKAKPTTTILSFFKKVDQDVLFISEDAKALSALNRAGGNLEDKSPDEADIRYNESNSPVKRRKLSSEPELPETIRPEMSPLLKCLVKKTDQKPSIPSSPSKGASKVGGFVFDDSDSETEPLDMNRGEFAAFQFKSRASSPSPIKPFIPHETSVLEELLRKAPGSPPLVSTSANPEVNKDPSNDHEDDDLFLGANVIDIAEEEREAMLAIRELDRREAALNRIVIDDDEGDFHGPDQEDKPVCPICYGSLQFASSDEATRHVNSCIDGNPTPLPTSPHPQPQAKSSSSSMFQGRTSLASKAAVPRPGQANPFQPPLTTANPALSAFSKLMAARAENKAWSEASDQEQASKGKPAHTRTCPFYKIMPGFSICVDAFRYGAVQGCKAYFLSHFHSDHYIGLSSSWCHGPIYCSKVTGALMKKQLRVATNWIVELEWDVCTEVPGTDGATVTMIPANHCPGSSLFLFEKKMLSAAIKKQRILHCGDFRACTDHVTHPLLRPETIDAISGKVRQQKIDICYLDTTYLDPRYAFPPQNDVISACAELCSEISADPDLPCKLWDHLQKGTKPKKLSSAAISKFFSNNTPQAQTQATLPNAPDKKLLVICGTYSIGKERVCVGIAKAMKTKIFAPSRKLAICKLLDDPTLTALLTSDPLAAQVHLQSLGEVRADVIEEYRRNYGTRFSRVIAFRPSGWTYHPPAVCSDGSRAPPSNSQPGQVPTTQLLHGAYWRARFNKSDVTAARGATKTAMCLGVPYSEHSSFRELALFVMSLNIERVVPTVNVGSDAARKKMKGWIDRWISERRKGGLLTVLEGDEDSGQTVDLWDGKIGNGGGVWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2Z6</accession>
    <name>A0ABR3Z2Z6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000086">
        <property type="protein sequence ID" value="KAL1894650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="242" mass="27260" checksum="CCF3FE048532F1C4" modified="2025-10-08" version="1">MNNVEVPKDLENILRSHPLWTEISRLNGIVITDRTVRKNAIELRPGSLYLLISSPTYKPLGKQQPRPMAKRWHWSLYSHISDTHGQTYHITHVNNDEEGPVSKTPQSSSNVQLGQTPVNGSNSWEFESNHIENMPQNIPVVCAIRIAKIDDELQCELEGRVAKVPLVPDISRRGFDGNDVIEDGISSCSWLLRALHDLDQEGWISIKLPSSADDIYNEAVYIGVQAEQIDAPLVKDSQFAYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3C6</accession>
    <name>A0ABR3Z3C6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DUF202 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_003526</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000085">
        <property type="protein sequence ID" value="KAL1894785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052053">
        <property type="entry name" value="IM_YidH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34187:SF1">
        <property type="entry name" value="DUF202 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34187">
        <property type="entry name" value="FGR18P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="DUF202" evidence="7">
        <location>
            <begin position="127"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="22"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="27"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1894785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="240" mass="25390" checksum="54F6F4B3F5C51F2D" modified="2025-10-08" version="1">MLTLATTATAATGAGSSTSIAARLPSTGVSHESVSGSSTLSSRHRTGSTSNEPRRRDPSEEWVELQDIPLGRASTAEDSVPRSGESTIAAEDRDASGTLPLGTSLWDRILWFWKSHVSVSVDIRASRDHLALERTFLAYLRTSAVGAVTGTTISQLFVLGSDNPGSGFNYRTVGKPLATACYIFAILTISVGTYRVWHLQKTMLNGKALARGSEPISVFVATACLLACLAGITVALDFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3E9</accession>
    <name>A0ABR3Z3E9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Band 7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003333</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family. Flotillin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000077">
        <property type="protein sequence ID" value="KAL1895150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027705">
        <property type="entry name" value="Flotillin_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13806:SF31">
        <property type="entry name" value="FLOTILLIN-LIKE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13806">
        <property type="entry name" value="FLOTILLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1895150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="388" mass="42948" checksum="6D1DC09F79DB59DB" modified="2025-10-08" version="1">MTIEETSSRQDLFKNRIQKDIQTELDQFGLRELRDAPGSTYLESLSHKAHGDTINQAQIDVAEAQSRRNVGEADQKGMQDCEITKINAETSVQKTERDIERAQSEARLKTERITLPRDVDISRIEAKRVTESCDEDLKRQVEMKRKDAEMERMRAVDVVKATILREAKHEQLTDTNAYKLRTEAEVEAQAKFQRITKKSDAFGYKTRVDADAESYAEAKKADMLLARQRNEAEGIAALANAYAKMAQAFGGPQGLRQFLMIENSRYVELAKANAAAIKGMEPKISAWTTGGAGSNGGSESSKSANSPGIDTIRNVYQMLPPLMTTINEQTGITLPEWQFGIIAIGADEINKRSLDRPGGNNPALSRFSVLAISGIICVLCALCVLCVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4C9</accession>
    <name>A0ABR3Z4C9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Chromatin structure remodeling complex protein sfh1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SFH1</name>
        <name evidence="7" type="ORF">Cpir12675_003399</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000079">
        <property type="protein sequence ID" value="KAL1895127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006939">
        <property type="entry name" value="SNF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10019">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04855">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="55"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="455"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="548" mass="61515" checksum="E8A4116FBAE03F0A" modified="2025-10-08" version="1">MTEQLQPQAFVSSYAPRLRTYNSSLLTPSLPSTTAVTGSSRTTKRGTTIINYAEDGYDDLDDDSDNPRRRGNALRSSRAQQQQLDDGTGGKDWSDVVGKETNIPVEVQPIWRDWTRHRAIRTDQQNVSQAALPLTLIPIRIDIDIPSYTPDRPFPVMPAMHEGLDMTLPQFRQQDPTPPYKLRDFFLWNLHETLITTDQFAQTLATDLDLPNRQQIVAEISRQIRTQLEEYAGVALHPLYRSQQIASASTQPPTQGRAVRGQSQLQNPSLAATPKVTANATMIAPEDDEFNPDDTYRCIISISLILSTVLYTDQFEWSLSHPPGTAELFAKQTCADLGLAGEWVPALTHAIYEAVLKLKKEACESNGWGAQQHNNDAAPDTIAGWRYDPEHLADAWEPKIEFLTKEEIEKREGDRERQLRRLRRETARFSNNTGSAVVVPFSGFGAVVEAEEERMGRGERTKKKRRFRSLSPSGRGTPDGGYALAMTDAERATWRCSHCRVWGSSVWAVRDGPAGAKTLCNNCGLCYERDSDLPRQMKNLHLSDARMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4K3</accession>
    <name>A0ABR3Z4K3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribonuclease</fullName>
            <ecNumber evidence="9">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_003350</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 9">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase HII family. Eukaryotic subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000077">
        <property type="protein sequence ID" value="KAL1895167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07181">
        <property type="entry name" value="RNase_HII_eukaryota_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.460">
        <property type="entry name" value="Ribonuclease hii. Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004649">
        <property type="entry name" value="RNase_H2_suA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001352">
        <property type="entry name" value="RNase_HII/HIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024567">
        <property type="entry name" value="RNase_HII/HIII_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023160">
        <property type="entry name" value="RNase_HII_hlx-loop-hlx_cap_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00729">
        <property type="entry name" value="ribonuclease HII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954">
        <property type="entry name" value="RIBONUCLEASE H2 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954:SF7">
        <property type="entry name" value="RIBONUCLEASE H2 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01351">
        <property type="entry name" value="RNase_HII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51975">
        <property type="entry name" value="RNASE_H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 9" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7 8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8 9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-2" evidence="10">
        <location>
            <begin position="74"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1895167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="355" mass="37674" checksum="93F2A58F965BF717" modified="2025-10-08" version="1">MSAASPPAAVDLTVDSLSVTSPAPTNTEADTTVTTAPLPPSINEAAIAAGETYSYYSAVPPRLAAPSDASLGEECILGVDEAGRGPVLGPMVYGVFYLPTDLSNSLLRETHHFDDSKVLTASVRANLMRTLADPTSGLYSTCGWAVTALSARAIASGMLQSVPYNLNAQAMDTTVALISGVLARGVNLVHIYVDTIGNPATYQAKLQALFPTVAITVAKKADSLYPVVSAASVCAKVTRDVALEVMYRPHASGAESCAKDGELIMDWGSGYPSDARCTSWLRDNMHPVFGWGSECRFSWGTAKDLIEGKTNPVKVEWSEEKEPAESRLTAFFKADTEQAKDELATWYGSSSELAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z554</accession>
    <name>A0ABR3Z554_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">xanthine dehydrogenase</fullName>
            <ecNumber evidence="5">1.17.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">Cpir12675_003223</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>hypoxanthine + NAD(+) + H2O = xanthine + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24670"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:17712"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.17.1.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>xanthine + NAD(+) + H2O = urate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17712"/>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.17.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the xanthine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.1.4" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000073">
        <property type="protein sequence ID" value="KAL1895364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.120">
        <property type="entry name" value="[2Fe-2S]-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.50">
        <property type="entry name" value="Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.365.10">
        <property type="entry name" value="Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.50">
        <property type="entry name" value="CO dehydrogenase flavoprotein, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_MoCoBD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046867">
        <property type="entry name" value="AldOxase/xan_DH_MoCoBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005107">
        <property type="entry name" value="CO_DH_flav_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036683">
        <property type="entry name" value="CO_DH_flav_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002346">
        <property type="entry name" value="Mopterin_DH_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014307">
        <property type="entry name" value="Xanthine_DH_ssu"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02963">
        <property type="entry name" value="xanthine_xdhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45444">
        <property type="entry name" value="XANTHINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45444:SF3">
        <property type="entry name" value="XANTHINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01315">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03450">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00941">
        <property type="entry name" value="FAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="MoCoBD_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20256">
        <property type="entry name" value="MoCoBD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000127">
        <property type="entry name" value="Xanthine_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01092">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55447">
        <property type="entry name" value="CO dehydrogenase flavoprotein C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="CO dehydrogenase ISP C-domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54665">
        <property type="entry name" value="CO dehydrogenase molybdoprotein N-domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="Molybdenum cofactor-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="10" id="KW-0274">FAD</keyword>
    <keyword evidence="7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="12" id="KW-0408">Iron</keyword>
    <keyword evidence="13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="14" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="19">
        <location>
            <begin position="24"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="20">
        <location>
            <begin position="256"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAL1895364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1415" mass="154137" checksum="CC42E647AFE6E7E0" modified="2025-10-08" version="1">MSPSAVVPETADKAALSFTTQFDDTLRFYLNGTRVVVDDVDPETTLLEYLRGIGLTGTKLGCGEGGCGACTVVVSQHNPTTGKIYHASVNACLAPLVSVDGKHVITVEGIGNVERPHPVQERIGKLNGSQCGFCTPGIVMSLYALLRNNDAPTSHDLEEAFDGNLCRCTGYRPILDAAQSFSITAGASSCGKATENGGSGCCMEQESGNGGGCCKSKLDSQPIKRFTPPGFIEYKPDTELIYPPSLKKHVMRPLMFGNKRKKWLRPVTLSQLLEIKAAIPNAKIIGGSSETQIEIKFKAVQYPISVYVGDIPEMRLFTFNDDHMEIGANVSLTDLEYLCLDAVKHYGLERGQVFAAMNSQLKYFAGRQIRNVGTPAGNLVTASPISDLNPVLWAAGATLVAQSMTKTTDLPMGQFFTGYRRTALPSDAVLTKIRIPITKPKNEFFRAYKQAKRKDDDIAIITAAFRLALDSAGIVTECSMVYGGLAATTVAAKKTESFLTGRKLSELETLEGAMSSLGLEFNLPFSVPGGMASYRRSLAVSLFYRYYHDILTTLGVKEEHVDKEAVPEITREIMTSSQDHRVAAAYERETFGQSKNHVAALNQVSGKATYIDDIPPQRNELYGCFVMSTKAHAKILSIDWVPALDMPGVVDYIDKDDLPSAQANKFGPPAFDEVIFAEDKVYTVGQSIGMIVATSANRAAEAARKVKVEYEELPAIMTMEEAIQAGSFHSAQKSIVKGDVQKALETCDHVFEGTARMGGQEHFYLETQAALVVPKSENGEVEVYSSTQNANETPARLAQSVERETLNLKVAGSTPALGSIPNAPVQLGYSNQQVFIAQALGVQVNKVLVRVKRLGGGFGGKETRAVPLACACAVAARKTGRPVRYMLTREEDIVWSGQRHPFLGKWKIGVNKDGMIKALDVDLYNNGGWSTDLSQAVLERGMSHVDGCYQVPNVAVRGLICKTNTVSNTAFRGFGGPQGMFVCESMMDEVADLLGISAESFRERNFLKPGDTTHFNQAVTDWHVPLMYKQVQEEAQYAERRQAVVEFNKKNKWKQRGLAIIPTKFGISFTALFLNQAGALVHIYHDGSILVAHGGVEMGQGLHTKMTQIAADALNVPLESIFIAETSTNTVANASATAASASSDLNGFAIYNSCQQLNERLAPYREKLGPEATMEKLAHAAYFDRVNLSAQGFYKTPEIGYEWGTNRGKMFFYFTQGVTAAEVEVDTLTGSWTCLRADIKMDVGQSINPAIDYGQIEGAFVQGMGLFTMEESLWLRGGPMKGALFTRGPGAYKIPGFRDVPQVFNVRLLKDVEWKELRTIQRSRGVGEPPLFMGSAVFFAIRDALKAARSKYGVEAATVKSAGGVRQTEDGAYAGLLHLESPATTERIRLACEDPIMQATKVTPKDGEQSFFLYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5N3</accession>
    <name>A0ABR3Z5N3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Vacuolar import and degradation protein 21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">eaf1</name>
        <name evidence="12" type="ORF">Cpir12675_003201</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000071">
        <property type="protein sequence ID" value="KAL1895562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014012">
        <property type="entry name" value="HSA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46459:SF1">
        <property type="entry name" value="E1A-BINDING PROTEIN P400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46459">
        <property type="entry name" value="E1A-BINDING PROTEIN P400-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07529">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51204">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="12" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSA" evidence="11">
        <location>
            <begin position="567"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="10">
        <location>
            <begin position="819"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="89"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="230"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="638"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="917"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="967"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1148"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="104"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="140"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="236"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="250"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="276"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="289"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="338"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="351"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="364"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="389"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="406"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="653"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1148"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1895562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1410" mass="153834" checksum="96CBF9A9EF5FAEB8" modified="2025-10-08" version="1" fragment="single">MSLSSIIPPRKRKYRELWAVAHGCEFNISDDRPKGDALPHNGSRPIQADDLLTLNKSSHIFAVQTPPNLHIDIIKPSLSLSDVLKFEGIPPPQATSKTLPDPTSPNGQSNATQNLPSAASNTPRTNLSPGAPTASISANSSTAVTKSQSSSIIIPSAKPSASPSPSLQPIPPTAASRAAQTSPKSILASLPALTNGAQPQVNPSLVTNGAQSTLPLKAATTTPTALTPALETNLAKPEKKLSTAPDHDTNAVTTETSSPESVAATATTPAAHDVSAGTSPGNDTTSIMDRPDVNRDEVNEPLLKRARLGEKQDTDSTSEAIRAQLLEESAALVRKQSEMSSTSGESSKPSNPLPQTLPPSPISENKEIADSRESNTTETDEKEDGKASNADSTKTTHTQPFLAPDITSSIEITTANPSTDEKLAEHSTGPELPNKRQKTMSEIMGKKAKTSGTINLKLLSRVNKNVANKAANPHVIFGKQPQRTRDLGSETPEGGYIPGSNYFTPLFFQTFIQSSKWMRPLDEVLYQAHKTITTTDLNVSLQDAQACRILRRVYHLQQGDKWSLRQPKRAVEPTRPPSHWDTLLQEMRWMRTDYRQEHKWKRAAARSLAFDCAEWIASTKEDRLAMQVPACIPQRHSDAMDIDGEKPPPVPDLDPSSSATTPTDSEELHEPLDFLPPSALFSLGQGDLVFEVQDSPTAESMILELPMFGAPLKVPGFDGACPDYDPDSHWRRPAIPLSKYVERGMNLKEIKPPHKPSRFRYALEDDAENAHPSKTQPLPPKCTQVALFSPEHRQTRDRLHMGHQFRPPTEFAMPPQSFFENRHSSMWTQNEDEELCGLVQKYSYNWSLISSLVNGKSQFISAAERRTPWECFERWIMLDGLPIDMQKTQYFKAYNNRIENAQRLLLQSYQMAQQQAAATPNGAVTPSKRRQSTPVKVERRRNQKHISIIDSMRKLAKKREAALQKQQQAANNATVRKPGDITQPRATKTPRDYSLMRFERDQAITGKMMSQIAAQREQRRQIIARQTQMFAVANGQIPHSNAAAAAMSTQLTAGNNPRINVPNPAMLTAAVAAGGQARPRIPIAPGVSGLQNMPAHLIPNIPMNGVGQVPINANIVAAAQQRLQQQHQPATQADVLIEVRRITEQQRALQQQQLPVSQQSTPNQSQSPHSSPQLSQGTMMPANSPPVRAGVPLTQQAILANAQAVMNSMSTNGTNLAAPNRNPHVTAALAANTTPRPTGQLAIPPSLLPTYNILETTIRQKHPTITPDQVRQLATTELTRMMLARQQTISQSAMTAASGGIQTPNMSNSMVSTSSPQQYAAILRQKQAATQAKIAQAQAAVQAQHQAQVQAQAHAQAQAHAQMQAKAQAQAQVLAQAQAQVQVQAAHAQHAQAQVQHMQIQAQQPQVLSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5Y0</accession>
    <name>A0ABR3Z5Y0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Peptide hydrolase</fullName>
            <ecNumber evidence="14">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Cpir12675_002933</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Extracellular aminopeptidase that allows assimilation of proteinaceous substrates.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the peptidase M28 family. M28E subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="14"/>
    <dbReference type="EMBL" id="JAWDJO010000063">
        <property type="protein sequence ID" value="KAL1896020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF56">
        <property type="entry name" value="AMINOPEPTIDASE YDR415C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 14" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0732">Signal</keyword>
    <keyword evidence="8 14" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044972611" description="Peptide hydrolase" evidence="14">
        <location>
            <begin position="19"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="15">
        <location>
            <begin position="163"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1896020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="397" mass="45126" checksum="8ED59DE5F34FBDD0" modified="2025-10-08" version="1">MRFTLALAALVATCTVHAASTGMDLVTLQFSETDVYRVTVKEKQQLKKAGTNFIDITDADVPLNFNRDPGTAIHKRDLVYIYPKRLTEQKWVNDRLGLIDQYIISGWLRKITSFRTRFYDSDDGLIAATWVRAELMNLINERSLGKTVEVDYFTHKNWRQPTVIAKIPGRGPDTIVLSASLDSIAFTENENEEFGSATAPGADANGSGAIALMETFRLLLTDNIIPLGLGWNTIEFHWYAASESGFQGSREILSSYHINEKPIAAILHLDKIGYYKPGTERRFGVVMDQTNHDLTNFIELLILEYCEFGYVETRNSFGSSDHTVAYGLGYPVARVMENSYDNMFQSFYTNEDVIENIDYDQMDGFVRLAFSFIYELVYFDMTSFSWPSSKESENLDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z602</accession>
    <name>A0ABR3Z602_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002956</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000063">
        <property type="protein sequence ID" value="KAL1896041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046460605" evidence="2">
        <location>
            <begin position="18"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="458"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="470" mass="51938" checksum="3C97C62FFFCB9045" modified="2025-10-08" version="1">MKFSLSLALSLCSVAQAGKLTEVGDLAQTGSPTEASDFVQAENLAQTSDLVQLDGPTLAGELTEADGLVQSDTPAPTGGLFETDSPFQADSLVQTDSPFQADSLVQTDSPAQGSKPAEDALFVQVTDVLNEHGYQVTYWGDSLLLFSPEYERGCEFVNAVAFYPSCKTAIIYIAKNDDEPEHKNKLSLTEVYNALSKRKGMEPNEMRMMIFEIEKEDTKTDWVIAKIRRGRKVDTWGEVRISPGDEEWNMILATEYYEKLLQVVIRPVQSIIIRTKDHTDWFNKVVHTNRIIFSFGPLESQTPVPGTATEVSDTNVYPKVYEEDEEAELLALIAEEDASDDEPEDESLDLVAEEDASDDQPQAESLDLVVEEDASDDESQAESLDLAVEEDASDDESQAESLDLVFEEDASDDESQAESLDLVVEEDASDDEPEDESLDLVVEEDASDDEPQDEMTYESASQILDAEQNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6C0</accession>
    <name>A0ABR3Z6C0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">methionine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Methionyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Cpir12675_003095</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>tRNA(Met) + L-methionine + ATP = L-methionyl-tRNA(Met) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13481"/>
            <dbReference type="Rhea" id="RHEA-COMP:9667"/>
            <dbReference type="Rhea" id="RHEA-COMP:9698"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000068">
        <property type="protein sequence ID" value="KAL1895762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07957">
        <property type="entry name" value="Anticodon_Ia_Met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00814">
        <property type="entry name" value="MetRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.20">
        <property type="entry name" value="Methionyl-tRNA synthetase, Zn-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041872">
        <property type="entry name" value="Anticodon_Met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023458">
        <property type="entry name" value="Met-tRNA_ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014758">
        <property type="entry name" value="Met-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029038">
        <property type="entry name" value="MetRS_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00398">
        <property type="entry name" value="metG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45765">
        <property type="entry name" value="METHIONINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45765:SF1">
        <property type="entry name" value="METHIONINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19303">
        <property type="entry name" value="Anticodon_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57770">
        <property type="entry name" value="Methionyl-tRNA synthetase (MetRS), Zn-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methionyl/Leucyl tRNA synthetase" evidence="13">
        <location>
            <begin position="16"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl-tRNA synthetase anticodon-binding" evidence="14">
        <location>
            <begin position="466"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="629"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF19303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1895762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="667" mass="74189" checksum="B3444A1D3D2AE83C" modified="2025-10-08" version="1">MAAKNPILPVEGKRNVLITSALPYVNNVPHLGNVTGSVLPADVFSRYCKARGYQSLYVCGSDEYGTATETKALEEGVDPVTLCAKYHAMHKSIYDWFNIEFDIFGRTPTAQQTAIVQEIFIDLYKNGHIEECASTQPFCPVESHNTFLADRFVEGECSICHDLGARGDQCDKCGSLLDPLEPENKDACGTQADEARATGWLINPRCKVDGTTPIRKTTKHLYIKLDQLGDRIVAWFNKASKEGEWSANCASITQSWINKGLKPRAITRDLKWGVPIPEGLEGLSKEDYLSKVFYVWFDACIGYISITANYTDGENTETRNWEKWWKNPDNVKLYQFMGKDNVQFHTIIFPGSLLGTDKEWTKVHKLSASEYLNYENGKFSKSKGVGVFGNNAKDTGIDADVWRFYLLSRRPETNDTEFKWEEFMDANNNDLLKNVGNLVQRTVKFCAAKLGSKIPDFGDYTDAVIAEHIKQTNVVLGHYIEHMEGIKLRAGIADILQLAYLGNKFLQDNKLDNKLLADEPQKCAAVIAYALNHIYLLASVLAPYMPNTAKSILTQLGMDSSLSILDTFDATAIKAGHVIGEPKLLFSVIPASKIEEWKDAYGGDELRRQKQEQAEKLALKKASKAAAKERKKAEKAAKGAVGAEAKAKSGEVEKKLAEATAGLTLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6Q3</accession>
    <name>A0ABR3Z6Q3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002976</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000064">
        <property type="protein sequence ID" value="KAL1896000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047327360" evidence="1">
        <location>
            <begin position="20"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="194" mass="22024" checksum="EB6BA3988F5B345C" modified="2025-10-08" version="1">MRSFALLASLLLPLLGVQAGKLEDHDYQVSYDEEDSSSSINIQSPHYPHFILNSISIEKEESMAVIYVAVNSEEPDHTKKLSLAEIFNEVCTLRDTSPSDLDLLVFDDLDSSTQTTIYSYRQQKGIGRKEDIEFTPGTSGWEKFSNLHYYNKAVSVNPGKSISKIEIKVMEAERLWDWADRVGSYDALYFTYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8X2</accession>
    <name>A0ABR3Z8X2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteophosphoglycan ppg4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000065">
        <property type="protein sequence ID" value="KAL1895969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="595"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="801"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="142"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="281"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="339"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="394"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="423"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="628"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="879"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="892"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="927"/>
            <end position="940"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="980" mass="103835" checksum="DC88F72F087599F5" modified="2025-10-08" version="1">MVSFFGLKLGGDKKKKSQPSNSPDSSTKSLRRLDQGKSDAAKTFGSPNGASTWDGTPVRKRLSSSARPGTSHSFRSFTTPRPVFMNGTATASLVDLQSFDRIPRPNRDSIRHTSETEARPGFASPDRFSMKPRAAVGAVGISSSPSSSRPTMRPSTSSGAHHEPLRRPSFSSFGREQLLFVTPRESSLTNQRSETGDIASPENRRPSNATEKPSLSESPVKYEALDSLFSGDEGVDEVLDNAPKPPPMATSISVNTAIPSQSEMSLASPMHSSPVVQSLDSPAHSYMSASSSRTHGPNQMISTSPLMHSNKGPPPGAFKPYSPAVALNGGNPTDRMRSPSDSSSQLASSSVPTLNESLSIQPPTLDTLTISTSGSPVISESPFSQFNFEFDLGPSSSLSSPSKSAVSTPATEVMSIMDRQDSFSRASTTSPSPSLTLISSHESVLSSRPSVSKSTSIRSTPSPSQSVRSARSIERPSFEKSVSTKPVAPSGLRVVRNAIPSIVPDTSGLGIAADRSSFVAKLQRTNFGARSPTPESDFVLHGDEALALQWEGPPVIRDVAAKRDTFTMSSPRRQSFSFNLDSSDHNQGLFAGEPQRQMSLERPKTSAGPATDFSSGLDGSPTQRARRASGGASSNSRLDAIRPSPLKIRTTTAKTVQAMPKSHLSVAPQQATLQTHVVPAQIAQVAEVGMFEAQSAEVSVASHLKTTSPKTSLQISTTTGIATDQASITSPATEGSLTADSAIASPALESPASVGAVANQLWPARVPYDSVRDKNGYAVPNPRGAPTAKSPAYQTSVLPLTSLSHGHSSPPPPARHPARGNVNADVPRASVRHAPSHPQRPKLVMPQDKFMSPRPAVQPPVSAVTQNTKVIWPLGVETPSPNSSSPGTLDKNTGEASHKRENKAQESVRDRVRNLEVQDRNRDRSRSPQAGYSSNGSRSPISGPGMRRDTSLLRNRPPPRPVRDDSVGAVPVSVTGDGFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z937</accession>
    <name>A0ABR3Z937_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-binding proteins Bright/BRCAA1/RBP1 and proteins containing BRIGHT domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">STB3</name>
        <name evidence="2" type="ORF">Cpir12675_002509</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000049">
        <property type="protein sequence ID" value="KAL1897188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018818">
        <property type="entry name" value="Stb3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28164">
        <property type="entry name" value="PROTEIN STB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28164:SF1">
        <property type="entry name" value="PROTEIN STB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10330">
        <property type="entry name" value="Stb3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="352" mass="37595" checksum="E54CE12F9DA8949A" modified="2025-10-08" version="1">MACAGRNIPQDLSSCDNLTAVAARKVPLTATAATQSLLPTPPNSISPGLQPHGLKAQLQRARLEPIDSDLDLLDNTNNDGSESPIDPSCDISALRLSQHYLPEILLNHGPLAIRHIMGYLTTAVPGFSAIPPTKARRLVVAALENYNETTPHQDIVYEKVGWGRWDARRRGQQYAIPRIPPIPMKGAHGNAASQGIPIAGGFNTCRRGKTFTSSNGTDSIVFSHDDRTMSIMDHEADKMSLDGSGSASCSEAPDEDDMMDDEDDVTDDEDWAAVGAAALRAESYSTSFTSRMGYAASPNLGSAAGMRAFPASFGGGMARLPQSSRVDYRALEAASGAEEREAVEALLKLRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z990</accession>
    <name>A0ABR3Z990_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">LPXTG-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_002736</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000056">
        <property type="protein sequence ID" value="KAL1896640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046695930" description="LPXTG-domain-containing protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="430" mass="45824" checksum="D4310C5073130AE2" modified="2025-10-08" version="1">MKSHILFVISTITVSALLSPVNSPCAVNCGNVLSSTASDEIQCSESSFSSGAGAVLKSCVKCQVESTFYNSDLTDVGAGLYNLRYASAFCLFGIPDGEALASPCITSTACGPLMNALNFNDLTTNSSSYDYCSIWQSNAVQLCMSCLGASSQSFLRNYVTTLNTGCQQLPANGTAISIEGDIFSTQVVNATVRDPLSTFTPESFVHNGVSLSAKVTISFAALVFLLTITGTGIICQGRRRRRAFLRTLEKKPSVAWAGSGSPLSPNQVQHYASTGKAASRNISDGPAPGWAASIAASMQRYTEDVNETPLSQKPLRGWDDSPLSAVGEKNIPSSGRYISPYSSQYSSPVSGAQEIPKSNALREIDLKLRCNEFELQVVGERTGGQYSEQHDNRVRDLDTPVLRQPSFSSLSGEGGPRTYSPQSGDLRRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9L4</accession>
    <name>A0ABR3Z9L4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002596</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000052">
        <property type="protein sequence ID" value="KAL1896947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1896947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="227" mass="25953" checksum="5D0A64E8F8B7C07F" modified="2025-10-08" version="1">MMQSLSSPINAAKRIFKRKSSLHGQHRIIDPEDSFRLSKKDEIDYFLVVSHEPKRWLPTRQGYTQYPSCILSPDGTIYQYSPRIDSKAGYITFSSWGCEHCVSQGVRENTDQDVKTGTMAVLLEIRTVKLDRLSRRAVKSVSGDGKESLLCFGQNTSPNDCVVCSSKKIRKMRDKLRWKTVSIPKHMSGNLDDASDEEDIDHRASWDKQWVEGHSSTPSEPLPWYKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9V8</accession>
    <name>A0ABR3Z9V8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000050">
        <property type="protein sequence ID" value="KAL1897002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="449"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="453"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="472"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="585" mass="66311" checksum="5A14F13765B739A4" modified="2025-10-08" version="1">MSKQMQPAYFEEAAEDESEDIMPGTRVTAATPRPPSKEVRKPKQSPPMSDDEHEARARTARRERRESRAAKKDRHMSRERSYERDRERSQEHKERKRERHVRRSSMHRPSKEHRNSANHQEEPSYDQQLTRTRSHSNRTPFNPTIPVAHPGYQGPPPSNVNFYHNHPSQMMPPPPQNMFAPPMNMGPGPGQMPGHIMGPPMAMHPQAQMMPPQLPGAPGNYGNYPPPPLNNYNHPPTTPGLDFAEAQNIRLGQRFGPSRPMSAQAVRRDSHHHDDYADEAPHGGQLTARRSSMRKREGDDERRRFAEEDKRKMPPPVGIPIRPKSARPVSGALSRPSHPERSSHLRNRSSVCEEDDLEEFGYCRPVSPDQDEYIPIGSSRPRQGSVSYSGRPSYHRTRRPSSYYGQDHLSGSSPENYETQTRAAHAYQNLTNSMKTLALTSDALQKVNRANYGGSNRSTRSGGSRGDESEWKQPSVTTQTTRSSNDEKVTIKFSGGSALVSISGRDIECQDGTELTLSSNQPMSIRNSMEPPALDSAPYYSENRMTRLERVPQRNRANSQAANSFTRGSFDRRYEAPIYNYTNRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA80</accession>
    <name>A0ABR3ZA80_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proteasome assembly chaperone 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000050">
        <property type="protein sequence ID" value="KAL1896996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032157">
        <property type="entry name" value="PAC4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16093">
        <property type="entry name" value="PAC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1896996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="138" mass="14701" checksum="C08DA780BEDC78D0" modified="2025-10-08" version="1">MASTLSQVTQVSLPLPRSIDTKIFVRMEVRDKSIMLFLTTAAVEDAGTTSSLGSLVYAISDRYNPAQPMATVLYSVESTVEPTTRLAKMIARKTGLPVYVSNSISLASTGMGGSPEEELEAFTKVVEVVAAKLPQTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAB3</accession>
    <name>A0ABR3ZAB3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_002536</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000050">
        <property type="protein sequence ID" value="KAL1897011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394:SF29">
        <property type="entry name" value="MYONEURIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="308"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="340"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="404"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="251"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="370"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="465"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="510"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="476"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="516"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="657" mass="72657" checksum="43F9F02E59036673" modified="2025-10-08" version="1">MSTPPTQQSPEDLNRIFFQTTAAFSSPPMAAPFFNGSMPTTMPMTFQQSPSALLLDTTGLGVQPSPNGMFDETALTRSASIGSMSSAGTPESHYASMVMPVVPSLPQTHSHQQQPQHPNQHHQSYNNQQTHQWIPLTVDNNGLNFGQNEYQLSSTGTEFNTVYHNVPMGQDLSKQASFGPPSDPFIAWTVPGSLMMTNDGQMPMALNTMHFATPMSTNPGMTSPQMVPTSPMGTVYPQHDVFPQSQAPLQPFYGSSTSRRPSTMTISSPGAGNSDDNSSHQKQMCTQCNKKFKDLKAHMLTHQEERPEKCPILTCDYHTKGFSRRYDRNRHTLTHYKGTMVCGFCPGSGSSKEKTFNRADVFKRHLTGMHGVEQTPPNSRRRGSAVMGPDSNEPLADCATDATGKCSTCPRRFRSPQDFYEHLDECVLRIVQQEDPAEAINAQCLSMVENDNDVVATLERNKVPLPSEAVAHNDDDCSDAEDNDEAGNAEGSGVLDSLLDGVKTSATMSAAKAKTNPANGVQKSRGMTYSRGGIPLNRPRGRKPRREYPSSWGFDKGQMNTKKRVLAVFEGQRRIAKDDMMINNEHEVRWHLADGNTYVTDLDVQTIRRAQGWHGATEEEKGPWVSDDPTEEDRQTMIALMEQQQAQHMQMAQMQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAG6</accession>
    <name>A0ABR3ZAG6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002424</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000047">
        <property type="protein sequence ID" value="KAL1897242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1230.10">
        <property type="entry name" value="MTH938-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036748">
        <property type="entry name" value="MTH938-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007523">
        <property type="entry name" value="NDUFAF3/AAMDC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21192:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21192">
        <property type="entry name" value="NUCLEAR PROTEIN E3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04430">
        <property type="entry name" value="DUF498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64076">
        <property type="entry name" value="MTH938-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1897242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="231" mass="25490" checksum="DFE68A00C1F6ABD7" modified="2025-10-08" version="1">MSGLLIRPSRLLSRLLRSTTHTCGLPQHIPPRLSLTSLSIGSLRANSRTLYTTQFHQARSTIEDKDYERYASEMGSLDVLGNLPVPGSSVTTCTPRGFKLHNGKMTDNGDAIMMFSDHVVRWRPWEHEKIGGHMRILNDKGQLDLPEEVFGVFGVMWPRPDMIIIGSGPSIAPMSPAMRDVFLRLGMRVDVLDTRNAAAQYNLLATERGVEAIAAALFPMGWKDGFGAGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAV7</accession>
    <name>A0ABR3ZAV7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cleavage polyadenylation factor subunit fip1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">FIP1</name>
        <name evidence="7" type="ORF">Cpir12675_002146</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000039">
        <property type="protein sequence ID" value="KAL1897803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007854">
        <property type="entry name" value="Fip1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051187">
        <property type="entry name" value="Pre-mRNA_3'-end_processing_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13484">
        <property type="entry name" value="FIP1-LIKE 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13484:SF0">
        <property type="entry name" value="PRE-MRNA 3'-END-PROCESSING FACTOR FIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05182">
        <property type="entry name" value="Fip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pre-mRNA polyadenylation factor Fip1" evidence="6">
        <location>
            <begin position="188"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="25"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="310"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="118"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="362"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1897803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="382" mass="39723" checksum="CB94922E53896248" modified="2025-10-08" version="1">MSTPPMDIDDDLYSNEGEAVATITATKAEQSTNKQAVGDAASESKGDFENDAEEAQDGEREDEDEDSDIDIIIDHQDEANADSGQQPKPSDSCTNPQRSTLDETTGKTSAAEDDTKHTPNTASAASTHLTGDSEVPTTAGPSSTTSVAPLPVPSADSEAKASSSSKIDINSNPIYKPAGKPIMSVVIDTDLGENDKPWRQPGTDVSDYFNYGFDEFTWALYAVKQENIRNEFNADAVLANQKKMMEEFNSMMMGGMPGGIPGGMPGGGMDPSMMPPEMQQMLQQMMGGGGGTGMGGMDMSQMDASMFNGGGNVGNGPPSSITAGGGNSEAQGGVSGNQEGFNGNTGVGQFGGMQGAGDFGRHNNGGGFMGRGRGGRSHWYLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAW4</accession>
    <name>A0ABR3ZAW4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA-directed RNA polymerase III subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPC31</name>
        <name evidence="6" type="ORF">Cpir12675_002148</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the RNA polymerase III (Pol III) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the eukaryotic RPC7 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000039">
        <property type="protein sequence ID" value="KAL1897805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024661">
        <property type="entry name" value="RNA_pol_III_Rpc31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15367">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15367:SF2">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11705">
        <property type="entry name" value="RNA_pol_3_Rpc31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000777">
        <property type="entry name" value="RNA_polIII_C31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="199"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="215"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1897805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="265" mass="29634" checksum="A0803F95BA075E6E" modified="2025-10-08" version="1">MSRGGRGGGRGGGAGGRRMPGGPSWDMGDEIDGRPSDLFPKYDVPQSQSLSKIEQRQINYFLLFRRQVHSTPLYTRKRTTANDTLKPRRIYGQDQVNKRYCLKSKATVDPFTAIETYSQRFVEEERTLPDFSTQPFCKDLFPPELHSTLDGNDCAPSRRRKRREKRLELSNVTSLHSADELYRSQQGDDAAARVRSLAANLDDGDDEAAGGPKGDDEEDHGGDDDEGEEDYAYDDEDGGDYDAEGYFDDGDNDDMDDGDDGEAVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAW7</accession>
    <name>A0ABR3ZAW7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA binding protein, heterogenous nuclear RNP-K like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">HEK2</name>
        <name evidence="5" type="ORF">Cpir12675_002501</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000049">
        <property type="protein sequence ID" value="KAL1897180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22455">
        <property type="entry name" value="KH-I_Rnc1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22456">
        <property type="entry name" value="KH-I_Rnc1_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22457">
        <property type="entry name" value="KH-I_Rnc1_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049786">
        <property type="entry name" value="Rnc1_KH-I_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="43"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="129"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="288"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="218"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="244"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="269"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1897180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="371" mass="39255" checksum="060E9EF8D2E62962" modified="2025-10-08" version="1">MSGAQDNHPSSEDLVDNVDLHDEPRLGPDGEPAPKTEEEYAQAQLTLRAIVSGKEAGVIIGKSGKNVADIRDETGVKAGVSKAVPSVHDRILTITGGCDAVSKAYAAVTKALMEGAPAVGMGGVVQNAGTHPLKLLISHNQMGTIIGRSGLKIKNIQDASGVRMVAQKDMLPQSTERVVEIQGSPEGIQRAVWEISKCLIDDWQRGTGTVLYNPAVRTQGSTSGGSGVGTGSSFSNSGRGGDYNNGSSRVTRTGNGADFSSSGQRSFNRRSDPEPPRAPPTHDENGEEIQTQNISIPSDMVGCIIGRAGSKISEIRRSSGARISIAKSAHDDTGERMFTIMGTAKANEKALYLLYENLEAEKMRRSQQANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB85</accession>
    <name>A0ABR3ZB85_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin 3 binding protein But2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002353</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000045">
        <property type="protein sequence ID" value="KAL1897497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1897497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="200" mass="22064" checksum="C044AAD673C64903" modified="2025-10-08" version="1">MSALAALPTAFAIPAKSNDAAWMAPREVSLEPRADAGSVFYPNISKVYDLTNNGNSFTQFCSAAASTFKNNVDQRSMLYRFDLDQNVQGKKCNLIFEATGITLYYESTFPITLQLFTTIEGTPLDCNENYLNNRRDKHIADITISSSSGDVQWAYHSDDYLLKSTDCPTSGSFGYEVAIAGESKYAAWTPPVMGLMINLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBB1</accession>
    <name>A0ABR3ZBB1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PWI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_002315</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000044">
        <property type="protein sequence ID" value="KAL1897527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1390.10">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002483">
        <property type="entry name" value="PWI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036483">
        <property type="entry name" value="PWI_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052768">
        <property type="entry name" value="RBM25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18806">
        <property type="entry name" value="RBM25 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18806:SF4">
        <property type="entry name" value="RNA-BINDING PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01480">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00311">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101233">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51025">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PWI" evidence="3">
        <location>
            <begin position="659"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="96"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="347"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="449"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="505"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="347"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="512"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="752" mass="83518" checksum="2E0259EE6CE36094" modified="2025-10-08" version="1">MSYNPYGAGQYGPPPGYGGFPAAINMSAPPGMVAPPGLGPPPGMSPAPGMAPPGVHTANAAQANRQSGLPMSFQPPSNLPSNINFNARVIRLGASNPKPAANGASKDSDNSASAHAPSSKFGNDRAEQNRANTRESIQALVPPKQDEKSRTIFIAKIPEGVNGNAGMESLLRSVGRLKRWDSSPSALYEATKTTFGFAQFEDPDSVSMALELLKDIEVPKKKQATPESMPVDDDNEFAGIEKTKLQIAADPITVKYLESHTESKGEDPHKEAQIQTAQEALKKAIRDLFYPPAVTKLNDATSASEAVEVVNINMTQEDELADIPAEMREMVAGEIAAFRERSTQRDIERLKKEEEMEERERQRNGAINGNRSPHPSIRGAPSGPRNANGNASSGMMFVNGGLSFADMSLYKDHSDTDASDEELNLRVVKKKKDEQYHMFLDAERKWVSRERSRTAALERERDREKHDASNLEKRRQEALEHDKQWDDEKERTRKVHPYYADHASWARKRAQARADETARDTADRHAEADEARREKKEMDKARGMADSFLEQHSKEIGSQSSIASTAVAASTPAPAPTAQPFKLSLGAAAQKAQAQRNGLQRRTIAEVEGLLDDEEHDQRTKRTLVPIKFEPISATASMTDEELQQAVRQLAQEIPTEKLELWAWPVQWDFLDESIMVEKLRPFVQKKIVEYLGVQEEVIVEVIEDHLRKHGEPSELVEELAEALDEEAEDLVKKLWRMVIFFTESEKRSLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBK9</accession>
    <name>A0ABR3ZBK9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DUF202 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_002079</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000037">
        <property type="protein sequence ID" value="KAL1898060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052053">
        <property type="entry name" value="IM_YidH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34187:SF2">
        <property type="entry name" value="DUF202 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34187">
        <property type="entry name" value="FGR18P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="187"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="DUF202" evidence="8">
        <location>
            <begin position="130"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1898060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="254" mass="27110" checksum="0E8BDEA880072ED2" modified="2025-10-08" version="1">MGTPPVSASVSASKRPASLSSEGGRAAPANETTNILHHNSSDNALNYQTSLPGTRHLSLENVSRRRSAVNARQGGRDSQSYGSGSGGFAGPESSTSENEDDSGDEKTGLLDKVRTAFRPVELENKGSVARDHLAIERTFLAWLRTSLAFASIGIAVTQLFRLNTSLADNEGSLPSPRLARLRHIGKPLGATFLAISIVILMLGYQRYSMATSWVIKGKFPASRATILLVAIVTFGLMLTSLAVVILVHPKIKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBM2</accession>
    <name>A0ABR3ZBM2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002310</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000044">
        <property type="protein sequence ID" value="KAL1897522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF17">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="NACHT" evidence="2">
        <location>
            <begin position="124"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="547" mass="62123" checksum="F96ED35E91EC8EEC" modified="2025-10-08" version="1" fragment="single">MFLIGDWAGQINDIQEAEKAVQYDIEQYNTQESQVQMHKLNNSTAAMQANVESIRAAVQILTKQQAKAREDDKYNECLKDLYVIDPRTDRKNIEVRKGGLLGDSYKWILEHQDLQKFKNEANSRILWIKGDPGKGKTMLLCGIIDELESDQSISPYCFFCQVTGGSRLNTATSVLRGLIYHLAQLNPRLLEYVRKKYDSAVMLKDSSLKNSVLIVDALDECVVNQELLLDFIKSSSAKWIVSSRNRPDIEQGLNGATQRVKIHLEINKDPVSLAIDFFIKYKVNELAQKKGYGDEVKEAVLEYLQSNAHDTFLWVALVCQELSSSKTRRWETLDKLKSFPPGLNALYRQILEEISESPHAQLYKEVIAKVLVVYRPISLEELRALVEALKDFYREGIEEVVASCGSLFTLHNNAVSFVHQSAKDYFLGEASDQVLPFDISHQHQVVLIRSLELLRQTLKNGIYNLHAPGCLINESTAPGPDPLAAINYSCISWVDHLHDSLPDVMARKNDTILIFFKEKYLQWLEALGFMSSIYTGIQAIRRLGTCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCI9</accession>
    <name>A0ABR3ZCI9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RNA polymerase II transcription factor B subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">TFB2</name>
        <name evidence="12" type="ORF">Cpir12675_002250</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the TFB2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000041">
        <property type="protein sequence ID" value="KAL1897750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040662">
        <property type="entry name" value="Tfb2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004598">
        <property type="entry name" value="TFIIH_p52/Tfb2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00625">
        <property type="entry name" value="tfb2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13152:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13152">
        <property type="entry name" value="TFIIH, POLYPEPTIDE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03849">
        <property type="entry name" value="Tfb2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18307">
        <property type="entry name" value="Tfb2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription factor Tfb2 C-terminal" evidence="11">
        <location>
            <begin position="466"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="349"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="349"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF18307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1897750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="537" mass="59621" checksum="876F9A1E4341AD5E" modified="2025-10-08" version="1">MSANPPATSLGEYLERLPGATLKKLYSQPSTALSIFRRMLPKLGEPLLEPSPRSRANGLTDNWWVLLAVALLAKKFVLTVLYMPEPLPLETIDAMVHPEYKREKDQALSSLKSLHMIQVTIPARDRKQEVQLVPTFRTSFREALEGSAVNNSFGVLSTLPVAAETDTAFLDKYARRRWDDILHYVVNSVGIQDTLGGGGAGPKQSVKELLVAGRLVEHRAGSMGSMGMGITRGGFTFLLQETNSQVWTLLLLWLDAANRASSTSLDAVDMLQFLFMLASMELGRAYDTASLTPERQNMLPFLVDIGLVYVPSHTPQQYFPTRFATTLTSSSNSLRSVRDGFIAAAHSSFGSSGPGAVSASGSGPTSTSGPASPGEDQGIIMETNYRIYAYTSNPLQIAVMALFCNMRSRFVNMVSGRLSRESVRRAIAFGITSDQIVNYLNAHAHEQMRRWAASRNRPVLPPTVVDQIRLWQLENERMKTTTGFLFKDFDHVDEYEATVSYADEVGVLVWRNDRMGMFFASKTEQIRDFLKVRKRAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCQ2</accession>
    <name>A0ABR3ZCQ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002181</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000039">
        <property type="protein sequence ID" value="KAL1897836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="278"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="358"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="524"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="245"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="364"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="438"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="524"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="554" mass="60081" checksum="216ABD71588B7EB0" modified="2025-10-08" version="1">MDAGGLAQMSTFPPAQASGLASRRGGTNVKPLSFDTLRSAEHNDTAVPTPRTSRGHMLAGLRTAPKSATAAAYPGSPVTANKPAISRNVSGSSLTSNSTEFNGPKSAMPRFAGHQKQQNYATLAQMTSQYTPDHILAPPEIQLDEQDQEHMDPDLYQRLVHTNMYLAQQQQHLQQQLLEVQAAAQQFQGLSQNPQMQQYRQQQQQLAALYGQTQPARQAQQIYAYVDPTTGQTQYFMDQGYPQYVDQTQMLLQQQQQQLQLQLQQMQLQQAHVQAQAQAHMAPQQAPRVQISPPTENAVPANRSSSPPKRNETPSDHAPLPPPSANAFRRGHKKVTSVAANNNANASNLTIATEITEDPKSAGPKSNSFPANASGTYGPGQARAGEHPVRQPRGPPSIEELRAKPTAKFEGSKNFATRTRRSAVHNLVRAGLVRRKGTSSSTGSMSPVSETAEEADTPITDNESDSGRSGSGSLAGDAESRANNRSPPSGWGAIGSDRPNSRSKDRKIENCVEDHSFAGIFKNAGREVEGQDQRKAPMLVLTSAEKRKTTPMYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDE9</accession>
    <name>A0ABR3ZDE9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Calcineurin subunit B</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Calcineurin regulatory subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Protein phosphatase 2B regulatory subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CNB1</name>
        <name evidence="11" type="ORF">Cpir12675_001945</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Composed of a catalytic subunit (A) and a regulatory subunit (B).</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the calcineurin regulatory subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000033">
        <property type="protein sequence ID" value="KAL1898400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45942">
        <property type="entry name" value="PROTEIN PHOSPATASE 3 REGULATORY SUBUNIT B ALPHA ISOFORM TYPE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="21"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="60"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="90"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="131"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1898400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="174" mass="19681" checksum="D2F5509D2A77DADB" modified="2025-10-08" version="1">MGNATSTVLDDIVQGSNFDREEVDRLRKRFMKLDKDNSGTIERDEFLSLPQISSNPLATRMIAIFDEDGGGDVDFQEFVSGLSAFSSKGNKEQKLRFAFKVYDIDRDGFISNGELFIVLKMMVGENLKDQQLQQIVDKTIMEADLDGDGRISFEEFTKMVENTDVSMSMTLQSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDH8</accession>
    <name>A0ABR3ZDH8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ATP citrate synthase</fullName>
            <ecNumber evidence="2">2.3.3.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">acl1</name>
        <name evidence="14" type="ORF">Cpir12675_001805</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.8" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000030">
        <property type="protein sequence ID" value="KAL1898698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003878">
        <property type="term" value="F:ATP citrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06100">
        <property type="entry name" value="CCL_ACL-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="entry name" value="Citrate Synthase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="entry name" value="Cytochrome P450-Terp, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017440">
        <property type="entry name" value="Cit_synth/succinyl-CoA_lig_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033847">
        <property type="entry name" value="Citrt_syn/SCS-alpha_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017866">
        <property type="entry name" value="Succ-CoA_synthase_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="SUCC_ACL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23118">
        <property type="entry name" value="ATP-CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23118:SF42">
        <property type="entry name" value="ATP-CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01798">
        <property type="entry name" value="SCOASYNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01216">
        <property type="entry name" value="SUCCINYL_COA_LIG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00399">
        <property type="entry name" value="SUCCINYL_COA_LIG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01217">
        <property type="entry name" value="SUCCINYL_COA_LIG_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="14" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CoA-binding" evidence="13">
        <location>
            <begin position="32"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1898698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="653" mass="70928" checksum="CE9F13C2456E6972" modified="2025-10-08" version="1">MVATAGGPSANDNITRFGAPSRPLSPHPAHALFTDKTRCFVYGLQPRAVQGMLDFDFICKRKTPSVAGIIYTFGGQFVSKMYWGTSETLLPVYQEVSKAMAKHPDVDVVVNFASSRSVYSSTLELMENPQIKTIAIIAEGVPERRAREIAHIAEKKGVTIIGPATVGGIKPGCFKIGNTGGMMDNIVASKLYRKGSVGYVSKSGGMSNELNNIVCQVTDGVHEGVAIGGDRYPGTTFIDHLLRYQADPDCKILLLLGEVGGVEEYKVIKAVEDGIITKPIVAWAIGTCASMFKTEVQFGHAGAFANSNLETAVIKNQKMREAGFHVPNTFEEMPAVLKEVYDKLIADGTIVPKAEPVVPKIPIDYSWAQELGLIRKPAAFISTISDDRGQELLYAGMPISDVFKEDIGIGGVMSLLWFRRRLPDYASKFLEMVLMLTADHGPAVSGAMNTIITTRAGKDLISALVSGLLTIGSRFGGALDGAAEEFTKAFDKGLSPRDFVDGMRKANKLIPGIGHRIKSRNNPDLRVELVKDYVKSNFPTHKLLDYALAVETVTTSKKDNLILNVDGCIAVCFVDLVRNCGAFSPEEAEDYMKMGVLNGLFVLGRSIGLIAHYLDQKRLRTGLYRHPWDDITYLLPNLSKGAPGAEGRVEVAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDI6</accession>
    <name>A0ABR3ZDI6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endonuclease III homolog</fullName>
            <ecNumber evidence="7">3.2.2.-</ecNumber>
            <ecNumber evidence="7">4.2.99.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase</fullName>
            <shortName evidence="7">DNA glycosylase/AP lyase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NTH1_1</name>
        <name evidence="7" type="synonym">NTH1</name>
        <name evidence="10" type="ORF">Cpir12675_001749</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the Nth/MutY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.-" evidence="7"/>
    <dbReference type="EC" id="4.2.99.18" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000029">
        <property type="protein sequence ID" value="KAL1898746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="entry name" value="Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03183">
        <property type="entry name" value="Endonuclease_III_Nth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030841">
        <property type="entry name" value="NTH1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43286">
        <property type="entry name" value="ENDONUCLEASE III-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43286:SF1">
        <property type="entry name" value="ENDONUCLEASE III-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00633">
        <property type="entry name" value="HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="9">
        <location>
            <begin position="282"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="76"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="157"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1898746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="534" mass="57942" checksum="B6A5E27829C97028" modified="2025-10-08" version="1">MTSASETSRFFANPASAAGRRVTRSQAVPITAEAPEFKSKAKDTAAQPARAVRVKVEPLALRGRTRSANTNASLIPKKEEDEAEQGKEGKKAGALAVATRSRSTRTIKSEPIADVEDFGGRRAIKRQRVSTARAKSSRVESPVSPPESESEHEVDNGSGSELSAPLSSDSDEYVSDDIRARKAKRTARKATAPRPQGRTRKPTASAKAKAKAMDLDHAPSSTLAAGIAPSNWEELYALVMRMRKPGGIAGDAAVDTMGCERLADRSASPRDQRFHTLISLMLSSQTKDTVTAVVIKKLQTELPPFAADVPAGLNLENVLAVHPDTLNEMIWAVGFHNNKTKYIKQTAEILRDKWNGDIPDSIAGLTSLPGVGPKMAYLCLSHAWHRTEGIGVDVHVHRLANMWRWVRTRSPEETRVALQSWLPHELWAEINWLLVGFGQTVCPSAGRNCSGCDVGLEGLCPAADKRKVAEGRKWAILGGDRKEEGMETKVEGDVKGITKAGVGDKNDVKLQALKEAGVTDETKDEISRVKDEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE16</accession>
    <name>A0ABR3ZE16_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_002105</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000038">
        <property type="protein sequence ID" value="KAL1898018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF30">
        <property type="entry name" value="MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="347"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="213"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="273"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="633"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="635"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1898018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="658" mass="75168" checksum="0F8688ACC1A91AE0" modified="2025-10-08" version="1">MASVTMAELSTSRDWEQTQAFTSEENRSILEVLKKDRERQNFVVVPPYLLDDLLVEDHHRESGIRTLIQPVDRKRSVSFHESSCTWINLKPATSPQGNIEHEVLAVIQTEKDIKFIVQIPGQPNEPSLLCELYYDPGSDYQIFLNRSSNLFSLARLSRDSDDDCDQMSRPTLDVWPGATRSLQPGTWRILIAFKPIVDFRILPKAPIIQYPCPQGSQSISADRLPSDQSLKRKRALDQDDGREIALKPPHDESNRRNNGVVIKFLQPVESPISIFPPTAGDEPEQPPRPIAPLGDRVGDTHPPAKSKSPPETNSNQSMILTGNALRDLPVNYIAHINAYQKDEYRLMRTDDLVHNSALSHIYKADHSNKREYIMVKILNTIDHKRPDNRKNIISQAITWERELRHHKRLKHDSIVRMVGGDARFLALYMEPVNAPDLGNAQQWRDKNNMFTGKPSNARQILRQTVDALEYIHAQGLVHNDIKPSNILYSVKTGAMLCDFGLASTVEESNNHQGGTPWYVPIEYLAHRRRGPPGDIWALGIVMLYLIRKIPLPETQHKQYLTWIIRDVHRNDIEPTVENEAQSARNQMQLWLDHIKNISSTLEERDPLEKLVSLMLRRSPTNRITAKSMMGILKVPPKQQQQQSSQPQSPSQIQPQPQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE58</accession>
    <name>A0ABR3ZE58_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Vegetative incompatibility protein HET-E-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_002226</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000040">
        <property type="protein sequence ID" value="KAL1897799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="192"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="309" mass="34764" checksum="E9C4E2D1A4F9DCB6" modified="2025-10-08" version="1">MTLDELYVLIESFKDLEKEDVKQAVSLCVSFLTVHENVVSFVHQSAKDYFLEKAIGKILPFGIPHQHQTIFLRLLDILQKELRRDIYNLTAPGCLIEEVSVPKPDPLAAIGYSCFFWVGHLDDSSSKGMVSKNDKILTFLSEKYLQWLEALSLLKGISIAGRGMEKLKSYSPDWIELKPEVEANWNVCLRTPEGHHQEVTPVVFSNDGQRLASGSGDNTVKIWDVTSGVCLRTLEGRHGKVTSAVLSTSVQPLLSPSFVDQLPSRHSEFDNYCISGDSVWVLQEQKRVLWLPQSYETLSAFRGHGNNLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEA3</accession>
    <name>A0ABR3ZEA3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_001641</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000027">
        <property type="protein sequence ID" value="KAL1898981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054585">
        <property type="entry name" value="NDH2-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706:SF50">
        <property type="entry name" value="NADH DEHYDROGENASE (UBIQUINONE)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00036">
        <property type="entry name" value="EF-hand_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22366">
        <property type="entry name" value="NDH2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="109"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="556"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="60"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="85"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1898981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="712" mass="78989" checksum="C908378DA37F2495" modified="2025-10-08" version="1">MRRPLPLSNASLTLASSTPRLNLRRLTSSPGVRSSVPSALFSTGLVGYYHHRQCFPSATKARHNSLGPSPMLQPSQCRLTSTTTTPPPLPLSPSPPLTPPKKRSRLLSLAQNTAAALGVTVTVLGIGIVGFFLYDASTYSEENTLVDVNVSKLALSPRTGGPKNLPIAEVYIDDNDCDEMKQHRDKPHLVILGTGWGSVAILKDLNPDDYHVTVVSPRNYFLFTPMLPSATVGTLEVRSLVESIRRILARIHGHYLCAKAEDVELADKLVEVSQQGTDGKEVRFYVPYDKLVIAVGSVTNPHGVKGLENAHFLKDVNDARQIRKRILENVEMACLPTTGDEERRRLLSFVVSGGGPTGVEFAAELFDLLNEDLARYFPKLLRNQISVHLIQSRSHILNTYDETVSKYAEDRFSRDQVNVMTNSRVKQVYEDKVVFTQKAEDNTITEKELPMGFCLWSTGVSQNSLCQNIAAKLNCQSNRHALETDTHLRVIGTPLGEVYAIGDCSTVQNNVADKVITYLRHVAQESGKDPEKVQLTFQQWRKIAKGAKKNFPQAVSHLKRLDKLFAEFDKDNSGTLDFAELRELLDQIDSKLTSLPATAQRANQQGQYLARKFNKIARHPGNFGTNDDAIFSGDADSATYKAFEYHHLGSLAYLGNSAVFDFGSGWNVTGGLLAVYAWRGAYFAQNVSLRTRMLMAMDWTKRALFGRDLVTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEB3</accession>
    <name>A0ABR3ZEB3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_001742</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000029">
        <property type="protein sequence ID" value="KAL1898739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02257">
        <property type="entry name" value="Peptidase_C19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF687">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="8">
        <location>
            <begin position="613"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="26"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="170"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="280"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="396"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="462"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="504"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="985"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1051"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="63"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="412"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="474"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="512"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1014"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1051"/>
            <end position="1061"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1898739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1089" mass="116762" checksum="4802CCC1FDEBF973" modified="2025-10-08" version="1">MVQPGSGVSASSSASVSASASASASTAPIVVSSNSPNVGNANHGSNAYGTTNAGTGPRRRGPNNHNHGNYYHHNQQQMYHHQHQHQNHHHHQNQNQHQHHQHQHQQPMAGPYGPYTIYNQQSQYYQHIPQYQNPMMHHGSYMPYHPHQTYSRPQPIQPFAPMAPMASIAASPAYPRPTPSPSLATPYQPPPMPQTLQQPQTPSSVHDSSHHGLTPPLSSTRDFTPGVPFFTDNLPTHPAPIVSSDAPAVVVSSQPYSSYPSAPPSVSSAVNSTVPSVVASASPFPPSTTVTTSAPPSAPAPVSVPVDASSNSPMATSAKASVTSQILDSSVESLQPKFHIPVPWLSCSESEWPLKAPRSRRRRRAPLQDGAELLRQHVVEPFYKGVMPRVTEKQVLPSATTEHAPPMPATPSVKNESVINSPPIASSDSTAPVQIHHTKAAAIKTAKPVVPVVPVVPKTLPRDVTKDNKLGDLTNASSGEKSGSQNSASLEAVNGQISNNAQSTVQENAAVSKAEAATPTSSTAEASAPASAPAPAKPVNWASLLKKSFPKGPTNSAEPAPAATGTRMAAVIGVPVSNGVSTTFSKEKTSSLADALRSFTVDGTNRIAFLEPRGLVNGGNMCYMNSILQVLLHCIPFYDFLDQVSKKATHSFNKSETPLIDAMIMFIQEFRVTASAPTAEKLYETLRSKERQFGEPFSPTFLYDEMKSSKRFANMEQGHQQDAEEFLGLLLQVLDDECTKVLATSNEPLGASNGNVSSNEANSVTAVNSGDDWMEVGPRQKAAVSRVTGQSSSSPISRIFGGYVRSELLKPGLKPSLTTQFYQSLQLDIDVPHIVNILDALKHMARKEVVIVDSAPSSAKNEKVCATTQTLICNLPPILVLHLKRFQFDAEGGTVKLWKNVGYPLELEIPRESLARQMLARLASEGQPLPKYRLSAVVYHHGKNASVGHYTVDVRRQDAREWIHIDDTKIEPIRTEEVAYAGLEGEGGHATSSSSNRFGLMDGNGGTDDDQGWKQVTSPANGNKRYSSTTNSAAVATAASASSTTAASTAASAAGTNNGNSKMSAFRGKQSQQMLNDSKVAYILFYQRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEJ6</accession>
    <name>A0ABR3ZEJ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Queuosine 5'-phosphate N-glycosylase/hydrolase</fullName>
            <ecNumber evidence="6">3.2.2.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4 6">Queuosine-nucleotide N-glycosylase/hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_001809</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the hydrolysis of queuosine 5'-phosphate, releasing the nucleobase queuine (q). Is required for salvage of queuine from exogenous queuosine (Q) that is imported and then converted to queuosine 5'-phosphate intracellularly.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>queuosine 5'-phosphate + H2O = queuine + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:75387"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17433"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:194371"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5 6">
            <dbReference type="Rhea" id="RHEA:75388"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the QNG1 protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.-" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000030">
        <property type="protein sequence ID" value="KAL1898702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019438">
        <property type="entry name" value="Q_salvage"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21314:SF0">
        <property type="entry name" value="QUEUOSINE 5'-PHOSPHATE N-GLYCOSYLASE_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21314">
        <property type="entry name" value="QUEUOSINE 5'-PHOSPHATE N-GLYCOSYLASE_HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10343">
        <property type="entry name" value="Q_salvage"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00035119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="359" mass="41456" checksum="5D15402F37212BFC" modified="2025-10-08" version="1">MSDDEADPELLELLRQHVYGKPQTNDEPNTGVLESVEYVYNDSIDVSIDMQSTKRAAEFIYSQMIAKKFSTDSWTDNELHPKEKDQKTLAFIVTMDLLNFCFWSEKNEEERFGIEYKGKKWTGYWGLVAALQRALDEDIPITSSDFWQNEAELDLDMMKHIFRSATDEEDPLLSSRLAILREAGMVIFEKLIASANGSAARLVNILSDRFPCFRDEATWPGRRKPVRFLKRAQILVADVWAAFGGASYGAFTDIDRLTMFADYRVPQILTSLGCLTYSPPLYNKVCGREELESRGKYEMQIRAASVWCVELLRREIKRNHPETNINAVMIDFYLYDTMKQMEAAGVETLPHHRTRSVWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZES7</accession>
    <name>A0ABR3ZES7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000035">
        <property type="protein sequence ID" value="KAL1898303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="276"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="519" mass="57785" checksum="2D426644FD13FC80" modified="2025-10-08" version="1">MEPSSNGIPATPHLVPSFSTEEDADLLAESAYELVSNMDTESQDGRLTPMLSLGTASQGGEDDVHSLADSSSDVEVDAEADADADADSHDSDHYEHETVPSQNEISQANNVCRRVACRSTTDLVDEDEDYDTTPLPSQTLIDYVSVAADAAKHETASVVTESDESEDEDDIVDGDGPDRDRTPRSSHLVVVDKDLSRRHILDLFRQCAAPESLSRSPSIDYMEDSLDKPSTPTLSMTLERPRDNASLSLSRNQGKPPHGHHSSKIAKKYGLPRMSILETLIAALLMLGFFGGALFGTYKLAAIEKPEVAVAHIGNGILPMNMPTATTTIVNYHTSVRYIYVTKTATPTPTSDPFSRFQLRRFWLPNDKPSLIYAKSTKAWAKLSHVGQSLKNKMRSKEPTCSVRSPKLDHPWATIRHKVQTWKDKTFANAKFAQAKDSIFHLKHRLAPFLSKEAQMVSFRARLVSAKCKMSYLRAQIQARSWWLHMRGHADESKRYAIRGDKYLKDQLSKLSRWTQGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF44</accession>
    <name>A0ABR3ZF44_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Golgi Transport</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">GOT1</name>
        <name evidence="8" type="ORF">Cpir12675_001888</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the GOT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000032">
        <property type="protein sequence ID" value="KAL1898423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045176">
        <property type="entry name" value="Got1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007305">
        <property type="entry name" value="Vesicle_transpt_Got1/SFT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21493">
        <property type="entry name" value="CGI-141-RELATED/LIPASE CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21493:SF9">
        <property type="entry name" value="GOLGI TRANSPORT PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04178">
        <property type="entry name" value="Got1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1898423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="145" mass="15951" checksum="EB606A0394683C52" modified="2025-10-08" version="1">MASMWLSDQQKIGVAFCSGDTSHFSFDISHLLDILTRERLLTFFRLQILFLIGLTLIIGPQKTLMFFARKQKAKGTAAFLGGITLILIRWPLIGFCIELYGILVLFGDFLGTISGFVRAVPVIGPYIAAGIDKLGVTARNSDLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG33</accession>
    <name>A0ABR3ZG33_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_001450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000023">
        <property type="protein sequence ID" value="KAL1899334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1899334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="157" mass="18268" checksum="4DA806A8963941B9" modified="2025-10-08" version="1">MVCSKTSLNWEKWSRQTTRNLRGFDILYLFKGLEEEVFQKATNFEKSPQKQPMDESNAMAVVRTGLNEEDKELSNNTETPKSCCTLLKCRHNKSNAHRSKYIFADLDKYMGKQWKVGDRASSRWYSLRTRISNYQGMSDLSKDSTTDNSLATFVIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGD5</accession>
    <name>A0ABR3ZGD5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BSD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001478</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000023">
        <property type="protein sequence ID" value="KAL1899362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3970.10">
        <property type="entry name" value="BSD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005607">
        <property type="entry name" value="BSD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035925">
        <property type="entry name" value="BSD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051494">
        <property type="entry name" value="BSD_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16019:SF5">
        <property type="entry name" value="BSD DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16019">
        <property type="entry name" value="SYNAPSE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03909">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00833">
        <property type="entry name" value="POAALLERGEN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00751">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140383">
        <property type="entry name" value="BSD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50858">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BSD" evidence="2">
        <location>
            <begin position="265"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="395"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="458"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="471" mass="50612" checksum="BD8590249ED860E7" modified="2025-10-08" version="1">MDIAYDHIQENAFNKDEAPSKNDAGASEKNEKQQQAQASLNSDIQEAYKAISSSAWGAKIGGFLGTVVKQSETVYQTAQKELTAASTEATRGFSDLRETLINRTRAISLSSPNAQPDSEGNSTTPTADTGRSIDKATTINEEEEEDLLSRLKKEAAKRLKDIQRAEDAADAALLQFGSNVRDFLKDAITVAPPTDADAAAQSTSRGAEGAANGQGATSTILFESKDAHGKRVIHSTRFDAQLHVLHTNPNTLLKAPEQSEQFTEWEKGFDVEAKTDDIAADLEEYSELRTTMEKIVPEKVSYAQFWCRYYFLRHSIETAENRRKELLKAAAASSEVDAWDDDSEDDESSSDEDSGSNSDDGDDDGKDSKADLSKKGAHIKRPVSAGSSRTIQPPKSKTTATATAAAGSSTSATSATKTAEGRKSNEGDSDTSYDVVGAASGVPSHAPSKATSKHDNESSDDDGSSEEEDWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGE0</accession>
    <name>A0ABR3ZGE0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pantoate--beta-alanine ligase</fullName>
            <ecNumber evidence="3">6.3.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Pantoate-activating enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Pantothenate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">pan6</name>
        <name evidence="12" type="ORF">Cpir12675_001551</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(R)-pantoate + beta-alanine + ATP = (R)-pantothenate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10912"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:29032"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57966"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantothenate from (R)-pantoate and beta-alanine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pantothenate synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.1" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000025">
        <property type="protein sequence ID" value="KAL1899267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004592">
        <property type="term" value="F:pantoate-beta-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00560">
        <property type="entry name" value="PanC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1300.10">
        <property type="entry name" value="Pantoate-beta-alanine ligase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00158">
        <property type="entry name" value="PanC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003721">
        <property type="entry name" value="Pantoate_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042176">
        <property type="entry name" value="Pantoate_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00018">
        <property type="entry name" value="panC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21299">
        <property type="entry name" value="CYTIDYLATE KINASE/PANTOATE-BETA-ALANINE LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21299:SF1">
        <property type="entry name" value="PANTOATE--BETA-ALANINE LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02569">
        <property type="entry name" value="Pantoate_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1899267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="416" mass="45007" checksum="A4A454599831E3E4" modified="2025-10-08" version="1">MAPGPQATVVRRLSAAALGTNYCSVSPCFSLPPHHYGPGFALGFRTRAQQAFLHPSLLTTGQRGHRTASMSSTREVIPSTSIRVLRSIDAMRQWRKPQAVDQRLVALVPTMGALHAGHVSLIRAAARENHHVVVSIYLNPAQFGVHEDLDSYPVTWAADVAKLAALDRELADDGANMGRVSAVFAPLTTEMYPSGFPGQEVASKGSFVTITPVSELLEGASRPTFFRGVATVCMKLFNAVQPTRVYFGQKDVQQTVVIKTMVRDFLMPIEVVIGPTQRETDGLALSSRNVYLGTRRRTAATVLKRALRAAEDQISQNGVADRASVLAAAMEVIEGMQAQQKTLKPSERVQFSVDYISLADPETMQEIDRVDVAKGVVLSGAIKFLPVEEPQEGEDLGHSGGPAVRLIDNIIVAGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGW1</accession>
    <name>A0ABR3ZGW1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_001164</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000017">
        <property type="protein sequence ID" value="KAL1899943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF13">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1899943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="437" mass="49998" checksum="E32065041A600DCC" modified="2025-10-08" version="1">MSRTLPSARWTSFANWDYNHLHERLHYILGVIDKPALIRHAESIKGQKFTMSEPFSAGQNWICFEMVGQEDGSLIIARVRLPRHPDYPFPISDAEKQYALECEVNTMRYVRCRLPGIPLPEVYAYEGPASPLAANVGAMYMLIQGFYGNTLFDMYPDIRDLPNSTQKHIIRQWTSVQALLATLTDPKIGSVVSFTELGDPVIGELANAAAEGLSPRGPFVNAHDYFSAVAKAAFLRVSRVASEGDDGPELHFQRLGAYIFKEIVQTTRLFRPSMAQYCFVHRNLTMHNILVDEDFNFVAIIDWEGAQTVPWQANHYPHPIELYLPDKVDRILRDRYHEMHAVEHRTAITRQIYIDTLLQAETLFTTQDREFRGTFSETLSSVASRVYSTFAGLNGFLANDKPLVYLMVQIAFNMDVEQVREYIHQKELEMEFEAFTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHN3</accession>
    <name>A0ABR3ZHN3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">proteasome endopeptidase complex</fullName>
            <ecNumber evidence="3">3.4.25.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PUP1</name>
        <name evidence="12" type="ORF">Cpir12675_001285</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.25.1" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000019">
        <property type="protein sequence ID" value="KAL1899702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03763">
        <property type="entry name" value="proteasome_beta_type_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000243">
        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024689">
        <property type="entry name" value="Proteasome_bsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF4">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12465">
        <property type="entry name" value="Pr_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="8 12" id="KW-0647">Proteasome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0888">Threonine protease</keyword>
    <feature type="domain" description="Proteasome beta subunit C-terminal" evidence="11">
        <location>
            <begin position="221"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF12465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1899702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="278" mass="30058" checksum="235B6CDB14FF00D1" modified="2025-10-08" version="1">MPGFDFSNYNRNVALHARGVPLPKATSTGTTIVGCIYNGGVVIAADTRATSGPIVADKNCEKLHYITPQIWCAGAGTAADTEFTTAIVSSNLELHAQSTGRKPRVVTCMTMLKQHLFQYQGHIGAYLVIGGVDPTGTHLFTVHAHGSTDKLPYVTMGSGSLAAMSVFESQWKPDLNEEEAVKLVSDAILAGIFNDLGSGSNVDVAIITKDKTTLKRGYIKPNERTPKLNNYKFQRGTTAVLNEKIIKKRDLSKFIDITDVLDIGKSKPEEAEKMEVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIX4</accession>
    <name>A0ABR3ZIX4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_001038</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000014">
        <property type="protein sequence ID" value="KAL1900354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.60">
        <property type="entry name" value="alpha-1,2-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1610.10">
        <property type="entry name" value="alpha-1,2-mannosidases domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2080.10">
        <property type="entry name" value="GH92 mannosidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005887">
        <property type="entry name" value="GH92_a_mannosidase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041371">
        <property type="entry name" value="GH92_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012939">
        <property type="entry name" value="Glyco_hydro_92"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050883">
        <property type="entry name" value="PNGase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01180">
        <property type="entry name" value="aman2_put"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143:SF44">
        <property type="entry name" value="GLYCOSYL HYDROLASE FAMILY 92 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143">
        <property type="entry name" value="PEPTIDE N-GLYCANASE PNGASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07971">
        <property type="entry name" value="Glyco_hydro_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17678">
        <property type="entry name" value="Glyco_hydro_92N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="801"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 92 N-terminal" evidence="3">
        <location>
            <begin position="25"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 92" evidence="2">
        <location>
            <begin position="275"/>
            <end position="748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="865" mass="96181" checksum="DDA6ADEEA2691C8C" modified="2025-10-08" version="1">MVSLKKPHILAVATLAAARQQLVEYVLTDTGSINGGNTFPGVTVPLGMVKLGPDLYTGHDSYSGYAPDGVLMGFSMLHESGTGGAPKYGVVAQLPVVRPVDDPLADWKVGRGRPDETEVGHYKFYMETGIVAEMSATAKAGILTYTFPNGSEPGIIVDVGHVLSSYRGQGLEQHYLGGRIEVREKSHELYYTGYGDYDNGWNRAEKWRVFFCGYFDSPPASFKTFIGTASTQVSNDTYSKVHERQSTTENVGAVFSFSRQKVTSRIGVSFISEAQACENVDYGIPPGTSVSKVRDSARKAWETQVLGKVTTRESNVTKLQQLYTALYFSNLLPTNKTGENPQWDSDEPYYDDIFTFWDTFRCTTSLLHILQPDAYEEFIRSWIDIWRHEGFMSDARSSFFNGAVQAGSNIDNVFADAFVKGVRGKIDWVDAYNAMLTNAEIVPPNNDDPRDTHGSTKEGRGALPDWLSLGYITRRFTRSVTRAVEYSTNDFALSQVASGLGFVDEATKYLNRSRNWRSHWNLDMKALGHSGFLGPREKDGFVDQDPLSCGGCYWGDDYYQGLPWEYSFNAHHDMAKIIDLVGGPNRFIDRLELTFTPNIVPGNGNFGHTIFNPGNEPSFGTPFLYNFAHHQYLSVNRSRFIAKSYYSPSPGGLPGNSDAGAMESWLLWNMLGLYPLTGQTTFLVGSPWLCDATIHLGEGRTLQITASNGSEDSFYVQELRVNGQLWNQSWVSWADVFERGGTLEFALGSKPVKWDIGPLPPSPATETAHPTFLLTEDLVPGAYSGVWIPPMLVQAWSIVRMFSVALNMAIGMLLVVCGIVSWRRVVIISRHLQANTGEREMLLKKNFDADAVDKETYGPRYKSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJD5</accession>
    <name>A0ABR3ZJD5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RAS1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ras1</name>
        <name evidence="3" type="ORF">Cpir12675_001011</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000014">
        <property type="protein sequence ID" value="KAL1900327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04138">
        <property type="entry name" value="H_N_K_Ras_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="214" mass="24087" checksum="B1D3B57AB122D182" modified="2025-10-08" version="1">MASKFLREYKLVVVGGGGVGKSCLTIQLIQSHFVDEYDPTIEDSYRKQCVIDEEVALLDVLDTAGQEEYSAMREQYMRTGEGFLLVYSITSRQSFDEITTFQQQILRVKDKDYFPMVVVGNKCDLESQREVTRQEGEALARGFNCKFIETSAKLRINVEKAFFDIVREIRRYNREMQGYSTGSGAAGGAHGSPNDMDIDDGNKTSGCCSKCLLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJZ6</accession>
    <name>A0ABR3ZJZ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sulfhydryl oxidase</fullName>
            <ecNumber evidence="6">1.8.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ERV1</name>
        <name evidence="9" type="ORF">Cpir12675_000968</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2</text>
            <dbReference type="Rhea" id="RHEA:17357"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:16520"/>
            <dbReference type="ChEBI" id="CHEBI:17412"/>
            <dbReference type="EC" id="1.8.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.3.2" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000013">
        <property type="protein sequence ID" value="KAL1900386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016972">
        <property type="term" value="F:thiol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.310">
        <property type="entry name" value="ERV/ALR sulfhydryl oxidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039799">
        <property type="entry name" value="ALR/ERV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036774">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017905">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12645">
        <property type="entry name" value="ALR/ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12645:SF0">
        <property type="entry name" value="FAD-LINKED SULFHYDRYL OXIDASE ALR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04777">
        <property type="entry name" value="Evr1_Alr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69000">
        <property type="entry name" value="FAD-dependent thiol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51324">
        <property type="entry name" value="ERV_ALR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 6" id="KW-0274">FAD</keyword>
    <keyword evidence="2 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERV/ALR sulfhydryl oxidase" evidence="8">
        <location>
            <begin position="85"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU371123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="195" mass="21234" checksum="C78AC49D99FD7D9D" modified="2025-10-08" version="1">MAAERTPSNAQQQDVADAGSVASGAIAPVGVAPKQMSKGVVLGKDGKPCRSCTSFASWASQTKSSLKTAEKPNAETITPSIPSDCPPDVEALGRSSWTLLHSMAASYPEQPSPGEQSDMLSFVKLFSKLYPCWVCAEDFQAYLARDEPRVKSRSDFGQWLCGAHNEVNTKLGKPVFDCSKWEERWRTGWKNGRCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKM7</accession>
    <name>A0ABR3ZKM7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000838</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="75" mass="8057" checksum="2A20452E809F8E4B" modified="2025-10-08" version="1">MPGNNKTTEGQEKEFTIQPVPGADQQNEGHINPKFAPFKANPGPVRQDLGGVPFEGTKEDRQARAAELNKKGGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLK7</accession>
    <name>A0ABR3ZLK7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">methionine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">MSM1</name>
        <name evidence="12" type="ORF">Cpir12675_000455</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00814">
        <property type="entry name" value="MetRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041872">
        <property type="entry name" value="Anticodon_Met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014758">
        <property type="entry name" value="Met-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023457">
        <property type="entry name" value="Met-tRNA_synth_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00398">
        <property type="entry name" value="metG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43326:SF1">
        <property type="entry name" value="METHIONINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43326">
        <property type="entry name" value="METHIONYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19303">
        <property type="entry name" value="Anticodon_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methionyl/Leucyl tRNA synthetase" evidence="10">
        <location>
            <begin position="26"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl-tRNA synthetase anticodon-binding" evidence="11">
        <location>
            <begin position="420"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF19303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1901585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="548" mass="61289" checksum="6C66442BCC0A3CCC" modified="2025-10-08" version="1">MRFKSTVMASDASSPPPEAPKPKPCYVTTPIFYVNASPHIGHMSTMVLADVYKRWRELCGQSAVLSTGTDEHGIKVQQAAARAGIPVKEFCDMNSAKFQDLAKMVGLSKHQWIRTTDADHADAVQFFWDQLQSAGYIYEAKHSGWYAVSDECFYPENATEQRFQPTTGRVVRVASETGNEVEFIEEKNYHFRMTALKTQLLEFYAQSPNWIEPQGRMRDVVNWVTYNLSDLSISRPSSRLSWGIPVPGDDSQTIYVWVDALINYLTQAGYPKALTSDGTLPADSIWPADLHVIGKDIVRFHGVYWPALLLALQLPLPKRILSHAHWTMDNAKISKSAGNAVSANFAVDRFGLDCMRYIMIRDGGIENDAKYSNETIAAHYRADLQGTYGNLLARLTRTVSWCVADAVKANKGATTTQLPIPEAVQKYTQAMESFRPAAACKAIMALLYTGNRYVSEMQPWNKVHSQEKKDNIVYQTAELVRVASILLLPIIPQKAGEALDVLDVRRDRRTMEFAAFGVDGDYGMGPVERTKSMSTTLFPPVLLAQEAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM15</accession>
    <name>A0ABR3ZM15_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000387</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42023">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42023:SF1">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="545"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="739"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="181"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="551"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="585"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="653"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="907" mass="100271" checksum="04412BA7E3BDECC3" modified="2025-10-08" version="1">MRTSTSNDSNPRDGLIVTTASPPTHIRRFRSLRSKARNQSSYEKASSSVLALFGSQLEIQHTTSISVETCRNPSFNPRSPSSRSPRRFAPATTPRSAITSPIKLRSTVTSPTQPSILSPNYVHGYSHKQSYSYSVGLVPNPPAPSSPERQPRQEPTHKDHPFLNGLAAHPICLSSLQQSLGASLQPQQPTLPPSSSVPRSRSQTVPDSCRPSNPLYLQRQQNQRVRINKSTSDLNFARESPLRTSPIKYTGVVGSEWKPRLESKLLTPTPNQPRQSFKPCLAMYTMSSRTPANLTMSHEISPPSSPDLAPQRKAPRNPSGDISPMGSSDEMASCDIQATPTDHTNIPAMRRERKTRALHAASSRDQMRQPKSEVGRQVFRMAEGRDMRWDAMTGEPTLGPGRSAQVKPADYAQGISRSPNSKSKTNSGRADEHLEPSNQILMSKTRVPHTYTQKVTGLRSASQPTPIQTQMHHQEQEQQIQPRNIPFQTKPEVRSAWKGASGRTAILDPVHDNKTGVKARRNVSISGVVSPVRSETGGVVPVIRKMAPSKSKGQTTPVTSPKGQSSAQVVDYPTPPRTVERDPPQKQTHIPSPTQHRHSPSDSVFKAQIPSRHISADLNSNKSIRRKPTPSTASINSVPRYPVPELSHESTCDDTQQPDWSQPASRFSVTTVATSIYSLSPEVNPVDVGEPLPEIPEAMKQLSEAAHIYPESTFQRSFSDKYCYDEEDNIPTKVEIHPVLTPPMSRDTPNKATPAKSPNQSIFTSINNPIPKSMATAQLFNSDTISIHTNGPGGKALPPAPPEASASDRVAHLSALLEALANRRININRSIAKMTEMMPRDNLLARPEVLKKREMEKLKVQALEDELAEVRREEYELGIKLHRARKRQDRDANFEGNSTLWVRRALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN12</accession>
    <name>A0ABR3ZN12_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alanine transaminase</fullName>
            <ecNumber evidence="8">2.6.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ALT1</name>
        <name evidence="8" type="ORF">Cpir12675_000347</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.2" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004021">
        <property type="term" value="F:L-alanine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045088">
        <property type="entry name" value="ALAT1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11751">
        <property type="entry name" value="ALANINE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11751:SF29">
        <property type="entry name" value="ALANINE TRANSAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="7">
        <location>
            <begin position="99"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="485" mass="53293" checksum="D946D58C323DD214" modified="2025-10-08" version="1">MATKSPRLTIDNINQRIVAAKYAVRGELAVKSEVYRQKLANGEAADLPFDQVISANIGNPQQLDQKPITFFRQVASLLENPQLLNHEDVLLNSLGYQTDVISRAKHLLKTVQSVGAYSASAGAPAIRESVARFLEERDGFPADPSHIYMSAGASSGVNTLLNIICASEKSGVLVPIPQYPLYTASLSVLSGKCVPYLLDEQKAWGTDLAVIKEAYSKSIAEGIDTRAIVVINPGNPTGASLSAQDIRNVIDFAAQERLVIIADEVYQTNVFIGKFQSFKQVLSQMKIEKPGHYDHVELASLHSISKGMVGECGHRGGYFELVGFNADVEAEIYKFVSIMLCAPVIGQCIVELMVNPPRQGDPSYALYKKEYDSIFHGLRERATALHAAFSQMEGVECGEPQGSMYLFPTITIPQKAVDAAAKEGRQPDEFYAMRLLDRTGICVVAGSGFGQKPNTFHFRTTFLAPGTEWVSRIVKFHKEFMDEFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN28</accession>
    <name>A0ABR3ZN28_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">MHF histone-fold complex component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MHF1</name>
        <name evidence="5" type="ORF">Cpir12675_000428</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TAF9 family. CENP-S/MHF1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22919">
        <property type="entry name" value="HFD_CENP-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029003">
        <property type="entry name" value="CENP-S/Mhf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22980:SF0">
        <property type="entry name" value="CENTROMERE PROTEIN S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22980">
        <property type="entry name" value="CORTISTATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15630">
        <property type="entry name" value="CENP-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1901559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="108" mass="12318" checksum="EA49741ACF399BED" modified="2025-10-08" version="1">MDDNETRQERLKTTLWFAVGKIVDQELLPRQQNSTPQFIGALTEMVWTLLENTAIDLENFASHAGRSTVTTDDVLLLTRRNPDLQGIIKDFVEKERSEKAATKARSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN63</accession>
    <name>A0ABR3ZN63_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L38</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL38</name>
        <name evidence="5" type="ORF">Cpir12675_000459</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL38 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002675">
        <property type="entry name" value="Ribosomal_eL38"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038464">
        <property type="entry name" value="Ribosomal_eL38_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10965">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10965:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01781">
        <property type="entry name" value="Ribosomal_L38e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1901589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="77" mass="9174" checksum="E38DCAAD504FBDC2" modified="2025-10-08" version="1">MPREVADIKQFLEICRRKDASSARIKRNKKEQQVKFKVRCQRFLYTLSLKDLEKAEKLKQSLPPNLNIVDLSKKEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNM4</accession>
    <name>A0ABR3ZNM4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MMS19 nucleotide excision repair protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000155</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MET18/MMS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039920">
        <property type="entry name" value="MMS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029240">
        <property type="entry name" value="MMS19_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12891">
        <property type="entry name" value="DNA REPAIR/TRANSCRIPTION PROTEIN MET18/MMS19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12891:SF0">
        <property type="entry name" value="MMS19 NUCLEOTIDE EXCISION REPAIR PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14500">
        <property type="entry name" value="MMS19_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MMS19 N-terminal" evidence="2">
        <location>
            <begin position="62"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU367072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1163" mass="126299" checksum="01DD85E61D70729B" modified="2025-10-08" version="1">MADFDQLALKFVLEDDHPTRDALAAEAAEVIKSAPRASNPIRKWVESVRPWILGDDGEAGSGDRIARARALDFLSTTLHLLDKGFLRLDQIKVLIAYFSSMFTIDHRSGILPSAKALSILASMEFFPVDSAPGMLHSVCAMGDEFRNQIPVTRLAVYELFTTCVTNPAIASELRSKQGPDLVFIKEMIAMCGSERDPKNILKWFGLLAIFLREFHPSTELSLEIFNTFSAYFPISLRASQHPSGITANDLKFALRDCFVANPTMAPHAFPFLLSKIEQGTGVTANVKASAFSQALSLDIILTLEAGIKTYDPCTTTIVPFADRIWSALKYEVRNGDVDDTIDATLDLFTTLTKRLEGDDLQTFALSVLRECTDDLSSSTYSAGAGKLLVALMRAKFPAFAPLAAPVVNHIRDALRHSKSPEHTSALLTLLNSVLAIRLLYLQKSEGLSDEEQLAFRAVDPTFVTLYESTLKKMFVERSAINRNAVQSLGLLASQPCAVEKGTLLLSHSTCQDITAELTNMIVQPSDIAPSVLQDAVEALQKIVSTLPEAFDQVLKSSLTTGKSSDDIDAFVILMSQVALIGCSALPKAGSTHSNFLLLTTSLLNALDGGIVKAQESAGFSHLTWSVYLTGLQAALMNFSDIYHAQWPLTPSLGLPDGATKDSWVSYIHKRFPSLPAYEGTTITSTKNNAPIDATDKPSDITDTDILLIGLYAVRGIFQRVLSVSDFQVNLTAPFNDGSDSSRRFIFFLGQLSTYVISQLTEKQQQLLSLQEEVFALFHSDVIKKVIDTVHPAEYFEEKIPDTLLSSPSIVPSCLDLSTSCLQALRPSVVSGLFSSGVGQEVIAQSLLSHDATEPTVARAYWLTVLANKHAFEKSPKLLALLESRLDVLVTSSDDVLVTANAVYGLLAGALRRYTGSSLSTSLDLFRKLTSNPTLGHTFAQWYDYLFSPKPRLAKAFHGLTKPTWTQRAYIELLVPLLQAALPCPTNNSTEKLAAANATIAVLAAVRHLSFTVYQDDAPVLVRTVLAALSTLPSSLVAAPALAILEAIMASSPTLLESHARSAIDVCLRISVLDTNTASIASSADNSWMPSGFDEISNPGPVLAAARKSALALLGQMPERFEHRHLVELAPRVKRSLAVASGDTVRAVRGIATKARMAWNTVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNT2</accession>
    <name>A0ABR3ZNT2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RanBD1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_000232</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053074">
        <property type="entry name" value="NPC_Nucleoporin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025574">
        <property type="entry name" value="Nucleoporin_FG_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000156">
        <property type="entry name" value="Ran_bind_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38697">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN SIMILAR TO S. CEREVISIAE NUP2 (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38697:SF1">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN SIMILAR TO S. CEREVISIAE NUP2 (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13634">
        <property type="entry name" value="Nucleoporin_FG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00638">
        <property type="entry name" value="Ran_BP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00160">
        <property type="entry name" value="RanBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50196">
        <property type="entry name" value="RANBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="2" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0811">Translocation</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RanBD1" evidence="4">
        <location>
            <begin position="1102"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="244"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="481"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="613"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="716"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="344"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="385"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="481"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="501"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="533"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="613"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="661"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="773"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="803"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="816"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="826"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="879"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="931"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="995"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1051"/>
            <end position="1082"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1901725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1222" mass="126152" checksum="940E9F01763AC598" modified="2025-10-08" version="1">MDLNTTPRARPALKFANRVYTSTPNSSSKRLSTFQSSSRKAARFDDSTLSHGAGNIFRASTLSAAATPSSSRFEPTIPNSTLKKSFSTSVVSATPNTQRVYRETVAKFTPRGMAAHSAPKELFDMRIPSPPLELNGEELTKRVPRDMERKGTVYADQYLGHVVPREFDDLQRRQFFCILDLRRLKYAANEVFAKKDWKLNIINFAKEFEKSRSLILLRYGLYEFQNVKPSDDVLRRWKISHGLPVDDEDEQTPVKSSATGSKRKAEDDICPEKSNPTTTANGSKRRIYEDDEATSKRKTDAAEGQPRKILKPSTSTPSATRALFEKIASKTATTESAEKEPAAGSSSLFESTASKPASNPFSKTVTSDTKNDSSSVTVYDDGEFEPDKGAEADKVCETQVAEKPLMASRASQKFNKGYDQNEAPTNSALAPAEEPTVNKTWTPDTPIKFAPAAAAATSSSSSLFGSSTPAAATPTTASLFGQKPAATAPTAASSTSLFGAKKSEEKKGEEPEKPKSTDAPVAPLFGAKPAETTPKSLFASTPAVASNTSSLFGSKIDTPSTTETSSLFGVGSSVPDVNSSKLETTASAPAASNTSLFGGVAAKPSLASSATTSNLFGGVSSATPAESSSGLAKVETPSLPNSASVPSLFGAAKSDGPGSSILDTKTNKPVDTSKPLFGNPAAATSATSGGALFGSTASVPASTSLFGSSKPSLAPPATFDFSGAAKTASSNSNPLFGGNPIEGSPMKQDSPVKRSLGDDSMQQDSPPASKKLFGAAAPSTTSSFSFGAAPAATAPSASFNFGAPQTTGTNSQPSTGGSGLFGGSSGFSFGSGSNGGASTNSSFTNPFSQASATASAAAPAAPTFNFGAASSTSTPATSFQFGGSSTQDTNESSGGNMFSFNASSAKPNSTRATTPLPPGKRPTLVPKSLRGRSNSPAVSQGNTSSLPNPFANGPSTNTGASFNFGTNDTSGNKPAPQFQFGNSTPANDASKEVDSNGGTTPSASATTTTKLTGTAEVPAVTTTTATAETTSASATAAPTETKPTQPKSLFSSVGTAATSASSPAATISTPATTTPLASTPVAGNDDAEAPQEQINLTAGGPGEEEEDVVYEVRAKMLLFVKDEDAKSPWSTQGVGPLRVLKHKVKGTVRMLLRREPSGHVAFNRALLSGSKYEATGKTVKLITTSVTGSGFETWIATVKTPEAAKALAEALETYKVAAAKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNU0</accession>
    <name>A0ABR3ZNU0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Beta-catenin-like protein 1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_000197</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039678">
        <property type="entry name" value="CTNNBL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013180">
        <property type="entry name" value="CTNNBL1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14978:SF0">
        <property type="entry name" value="BETA-CATENIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14978">
        <property type="entry name" value="BETA-CATENIN-LIKE PROTEIN 1 NUCLEAR ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08216">
        <property type="entry name" value="CTNNBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01156">
        <property type="entry name" value="DUF1716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Beta-catenin-like protein 1 N-terminal" evidence="7">
        <location>
            <begin position="86"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1902090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="585" mass="64197" checksum="5BD7E7E180142081" modified="2025-10-08" version="1">MASIDEIFNGVKTSGSKRKNEAIRDPNEIYKAARTGNTTPRHSQADDDDVEAGPALPPVDDEDIGPAIPEDDNDDEEGRFFGGGISKNEQEVLDYVQGDDAPAENIDEPWLRRKVIALEKHINKNAELRARFEGEPQKFISSEADLDADIKALSILAEYPALYTELAKMGSVASLVGLLAHENTDIAIDVLQLLGELTDDEVEATEDQWDALVTPMLDADFLDLLQSNLVRFNEDDEADSSGAYHGLWILENLCSGRSTIGERVATHKPLVTYLITRASKAEPTGVSQNTQYSTEVLAILAQSSKKACNSLVSLNAIDTVLQLVAPYRRKDPAKGSAEEEYLGNLFEILVCLVDGDAGKAKFLEAEGVELCILLISDSKKAKTSALRLLDHATDNKADFKSTTTATQVCMRVVDAAGLKPLFAAFYRTKDRDMLDHLLGLFASMLRLLPLDEAQRIRLLAKWVEKDYQKLGKLIERRQSFARSLAAVDSKHGAVDGKLPSVADETVEDEFLTDQLSAGLFSLHNIDLALAWLVAEDGGVRSKVQREVGYSKILKTLEFLLEGINGESEGDEDTRAMLTTLVSLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNX2</accession>
    <name>A0ABR3ZNX2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">N-glycosylation protein eos1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021100">
        <property type="entry name" value="N-glycosylation_EOS1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28147">
        <property type="entry name" value="N-GLYCOSYLATION PROTEIN EOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28147:SF1">
        <property type="entry name" value="N-GLYCOSYLATION PROTEIN EOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12326">
        <property type="entry name" value="EOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="306"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="336"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="371"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="399" mass="42883" checksum="1CEA014E44D5F3C7" modified="2025-10-08" version="1">MSRPSLLHVDDPPPPFDLVVSTSSNNGNHRIVQSVQPLSSSSTALSSSVPASSNAIHQRKPSVPASVSTASATPSSQSYLLHHHHHHPHPHQHVSLNSSTAAMIAAASSTATAAALPEAAALSPVPAPPGGSNMNYTNIPSASRPATHGMKIAPTKSLSAAIAEAAAKNPAGSDVIQASLLAPRVAVILNVPKSWHLPLFVGRLISILPAILYGWRPALQLLDQILPGDAGDSVVVFPRTEIALASMWCFAAGYLSFFFADCLMSRWLINYTPQATIVRLLSINAVNFYMTNTTLKLFGAFHDLRLFLPAWIAISAVLTGAYHVTHQKINIRKETITSINVFSIASSISMVSLLLLAYGARTDLPDIPLVVYSRLLFAQFLKLLVRLRASLREHHQQRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPV7</accession>
    <name>A0ABR3ZPV7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">D-arabinitol dehydrogenase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_000104</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08234">
        <property type="entry name" value="threonine_DH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050129">
        <property type="entry name" value="Zn_alcohol_dh"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43401">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43401:SF2">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="6">
        <location>
            <begin position="33"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="5">
        <location>
            <begin position="172"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1902204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="343" mass="37220" checksum="954BDDF232D52E5D" modified="2025-10-08" version="1">MALSKATVTNVHYSYEKPEDFSIVEVPLPTLRENDVLVKVKACGHIHEGEFIAKFPLIPGHETVGVIAAVGPKVKGFNIGDRVAADNSELCQECFYCRRGKPLLCEQFEAHGVTMDGGFAEYCAYPAAKVFKIENLSDIDATLLEPASCACHGLERIAPALGSHVLMFGAGPTGLMLAQLLHHNGGCKVTIAAPGGLKMELAKKLDAADTYIELSRNNPQAQFEALKRDNPYGFDIVVEATGSTKILEDAIHYVRRGGKLVVYGVYSNTASVSWPPAKIFGDEITILGSFSETYMFPATIDYLDSGKVKTEGIVNKTFKLEQWGEALESIRNKSAVKAAIVFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQJ4</accession>
    <name>A0ABR3ZQJ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA-directed RNA polymerase subunit</fullName>
            <ecNumber evidence="12">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">RPO31</name>
        <name evidence="14" type="ORF">Cpir12675_000190</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="12"/>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02736">
        <property type="entry name" value="RNAP_III_Rpc1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02583">
        <property type="entry name" value="RNAP_III_RPC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.180">
        <property type="entry name" value="RNA polymerase ii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="entry name" value="RNA polymerase II, clamp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="entry name" value="RNA polymerase Rpb1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035698">
        <property type="entry name" value="RNAP_III_Rpc1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035697">
        <property type="entry name" value="RNAP_III_RPC1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015700">
        <property type="entry name" value="RPC1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006336">
        <property type="entry name" value="PRK08566.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48446">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' N-TERMINAL SECTION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48446:SF1">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' N-TERMINAL SECTION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12 14" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 12 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 12 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase N-terminal" evidence="13">
        <location>
            <begin position="260"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1902083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1498" mass="166758" checksum="8BE92C66FA3C15EB" modified="2025-10-08" version="1">MEHTAGSPVKQQLVDKLPKRFKAMKFGVQSQQDIFNQSVLEVSDRMLYDIEKNRTPYLHGPLDPRLGTSSKMSKCSTCNELLQTCMGHFGRVKLPLPCFHIGYLGFIITILQNICKTCAHVMLTEKERQSFLKDLRRKDLDNLRRTQYAKKINEQCRKAKTCPKCNAINGTIRKVGVLKLIHDKFTTFNKSTAAKKVPPEEKKIFDRSFEEARKQNPELDKHLKKAMEDLNPLRVLNLFKLISPTDCELLGLNPVEGRPEMFIWQSVPAPPVCIRPSVAQDNASNEDDITTKLSEIVWISGMIRSALQRGTPISTIMEQWEYLQLQIAMYVNSDVPGLQQPGFGKSVRGFCQRLKGKQGRFRGNLSGKRVDFSGRTVISPDPNLGIDQVAVPILVAKNLTYPETVNRQNIEKLRQCVRNGPQIHPGAQQILIKDETGFYKQSLKFGDRNKTAEQLRFGDVVERHLEDGDIVLFNRQPSLHKLSIMSHLAKIRPWRTFRLNECVCGPYNADFDGDEMNLHVPQTEEARAEAITLMGVKNNLATPKNGEPIIAATQDFITAAYVFSSKDRFYDRRSFTQLCLHMIDSQTHLELPPPAILKPEALWTGKQLFNMLMRPNKQINVLVNLDAKCRDYSPQSNKAPDMDPNDGWLVIRNSEVMCGRMDKSTVGDGKKDSVFYVILRDFGPDAAVIAMNRLAKLAARALGNHGFSIGIGDVYPSLPLTLHKNTLVDHAYKRCDELIDTFKAGKLEKAPGCNLEQTLETLIGGILSKVREQAGAYCIKTLSRNNAPLIMAKSGSKGSNINVAQMVAVVGQQIIANARVPDGFQDRSLPHFHKNARQPPSKGFVSNSFYTGLVPTEFIFHAMAGREGLVDTAVKTAETGYMSRRLMKSLEDLSTQYDDTVRTSSGGIVQFQFGADKLDPVDMEGSAVPVNFKRTFTHAESLTWNNDDPMLLPHEVRQIRDDMLNPERKKYPRIGLLGDKLGYEDQSDYAIDEHDGARNFLKTIDEYIESRAKSIEKVMVDAGLDPALTRKEIERLGSPIATQLGHVERVSKISRTTLARFIRLCLEKFKKAHVEPGHAVGAVGAQSIGEPGTQMTLKTFHFAGVAGMSITQGVPRIKEIINASSNISTPVIACPLENDRQIEVARVVKARIEKTFVSDIISYLEDEWRPECAKVVLQVDMNALADMNLGISTGDIANAIFKYRKLKLSKGDIYEPYPGRLEIAVRVDADKPRKVAKTTRAQQMDDQGDLYLRASYLRRTLPFVPVSGYPDAVRAIIQTSEESLNKVIVEGYGMRSCMTTEGVIGAQVTSNNIMEVKDVLGIEAARATIAGEIGEVMKDMNIDPRHMDLLADVMTYKGEVLGITRFGLAKMRDSVLQLASFEKTPDHLFSAAAGMKTDAIEGVSECIIMGQTMSIGTGVFQMVRRLGISPNDVVPKPTVFEDIWSEKTKAKKALPKQKAQQQRHNGVNGVNGVSGVTGINGLAHMNGHSNGGDVVMVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YCI4</accession>
    <name>A0ABR3YCI4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein sof1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">sof1</name>
        <name evidence="4" type="ORF">Cpir12675_006921</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000425">
        <property type="protein sequence ID" value="KAL1886026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051733">
        <property type="entry name" value="WD_repeat_DCAF13/WDSOF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22851:SF0">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22851">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA U3 SNORNA ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="107"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="150"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="323"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="366"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1886026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="410" mass="45727" checksum="728F8A6114C0DE83" modified="2025-10-08" version="1" fragment="single">MKIKTLSRPSYKPGATETKVSRNLDPSIHPFAKFVYTVLSGLGIVMHVIANTLINRAREYTRTINAVKLERMCVFPDNTLSVGIVRLATFTDAFLIRFAAPFLGQLGEGHVEGVYSMKMDPNSLDRCASGSGDGVVKVWDITSRSHVWTAPSHDHIVKGLAWTTDQKLLSCSADKSVKLWDPYNTASESAPISTWLGTNAFTSISHNRSKSSFATASNVISIYDLNRHSAAPEVLKWPNREDTINAVEFNPTETSILAACATDRSVIMGDLRTGQLSRKFILKFASNSVSWNPMESYNMAVASEDHNIYIFDTRMWNRALNVLQDHVAAVMDVSFSPTGQELVSASWDRTIRVWNRDKGHSRDVYHTKRMQRVLSAEWTADSKFLLSGSDDGNIRVWRANASKREGITNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YF32</accession>
    <name>A0ABR3YF32_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_006861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000397">
        <property type="protein sequence ID" value="KAL1886914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1886914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="143" mass="16163" checksum="E0882242FD1028E0" modified="2025-10-08" version="1">MPKILVPELQDGNAVVDPTAIKQAILDTELPAIDEVPYSEWSEEFQKAIIITKASALFDSSKMEYQISQLLVAEKTRIKELKRCAPRIPFKKKDTHPEMLCIIHERSQNSKVATAVAAFLEITSQRLTSLEDLARLILYLQPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFD0</accession>
    <name>A0ABR3YFD0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_006766</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000370">
        <property type="protein sequence ID" value="KAL1887003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1887003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="156" mass="17970" checksum="409AE35523888F5C" modified="2025-10-08" version="1">MRIVFKPADILSLFDANFTHEQGFVFLFGTDVTPIVSKQDAIYVLEGTSRQCYALRIPVHLSKKCKRDITHAVQRQVNLLRRLADSGFSWSPRLMAQNIEFDNHIGFPYVILGWMEGRALKWDDKTPSERGVRNKVLWQMADIILELALCTQETSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFW5</accession>
    <name>A0ABR3YFW5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">chitinase</fullName>
            <ecNumber evidence="4">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">CHT4_3</name>
        <name evidence="14" type="ORF">Cpir12675_006649</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000341">
        <property type="protein sequence ID" value="KAL1887213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06548">
        <property type="entry name" value="GH18_chitinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF317">
        <property type="entry name" value="CHITINASE 12-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="9 11 14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 11 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047208302" description="chitinase" evidence="12">
        <location>
            <begin position="23"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="13">
        <location>
            <begin position="47"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1887213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="445" mass="48842" checksum="DD4636CA20AD897D" modified="2025-10-08" version="1">MLSKSLVASVLAIASAIVPVTAAPRTKQYTAANVARTNAADNLPNGFINLVYYHDRSIEERKFRASQMTVDKLTHVNYAFLQPYQNGSVIPGNLQNDVIEPLIEGETQPYTYEENGVIKYNALGCVKDLFMLKQNNRYLKTLISIGGWDWSGNFSIIAADEAKVEIFVTESVKYMADWGFDGVDIDWEYPQNKEESVNFISLLKRMRKALDDYAAAVTPGYRYLLTIAAPAGPANIQQLDMKSLGEILDFINLMAYDYAGSWSSKSGFMANVYPSKSTPAATDVNTEAAVNAYLDGGVPANKLILGMPVYGRGFENTEGIGMPFEGIGPGTWEPGAYDYKALPFEGAKEVFDEETLGHYSYDPVKKQLISYDTPQVVTRKVEYLSSKGLGGSMFWEASADKLGEGSLIGASYSALEKTAGSPSCSENQLYYPNSMYSNIATGFMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG16</accession>
    <name>A0ABR3YG16_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SnoRNA-binding rRNA-processing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ENP1</name>
        <name evidence="3" type="ORF">Cpir12675_006661</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bystin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000344">
        <property type="protein sequence ID" value="KAL1887177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007955">
        <property type="entry name" value="Bystin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12821">
        <property type="entry name" value="BYSTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12821:SF0">
        <property type="entry name" value="BYSTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05291">
        <property type="entry name" value="Bystin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="52"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="94"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="111"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="492" mass="55211" checksum="DC21571B237F2B51" modified="2025-10-08" version="1">MPKAATTPTAPRRRHNPLELDYMQSGPLKTKAPKRVKKDTEQGPGFVDAKQTRTILSLGQGLTQEDQDERTAKQKAAASPNREAFNYDARLAELEEAEDDEPENTDMAGANDDEEAWGDEDDEIEHLDVDPEDLEAYRKFLPELDQDPLLAHGWDQKPDDGMAEDDEQPTNLADLIMEKIMQHEADMERRESGPIDDELPEKVVLVYTKIGEILSRWKSGKIPKPFKVLPTIPRWEEIIQLTKPESWTANAMYEATKIFTSGKKDTSRVFLEHVLLPRVREDIYEHHKLNVHLFKAVKRALYARSAWFKGFLFPLVSNNLTSREATIIGAVLTRVSVPILHSAAALAGLCEISAQGASDGIEGGGAVNILIKALLEKKYALPWSVIDSLVFHFLRFRSVDPASIKQADGLDIEETTNARLPVVWHQCFLAFAERYKNDITEDAREALLDLILTHGHPAISPEIRKELLSGRGRGVVEEPQSVALDGDDTMML</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGG5</accession>
    <name>A0ABR3YGG5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein disulfide-isomerase erp38</fullName>
            <ecNumber evidence="7">5.3.4.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ERP38</name>
        <name evidence="7" type="ORF">Cpir12675_006632</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000338">
        <property type="protein sequence ID" value="KAL1887234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02998">
        <property type="entry name" value="PDI_a_ERp38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051063">
        <property type="entry name" value="PDI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005788">
        <property type="entry name" value="PDI_thioredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01126">
        <property type="entry name" value="pdi_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45672:SF11">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE C17H9.14C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45672">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045048453" evidence="5">
        <location>
            <begin position="19"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="6">
        <location>
            <begin position="7"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1887234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="148" mass="16158" checksum="3B78F9B025107E41" modified="2025-10-08" version="1" fragment="single">MVSLRTLVVTALVAVASAKSAVIDLVPSNFDDVVLKSGKPTLVKFFAPWCGHCKTLAPVYEELAAGYEHADDKVQIAKVDADAERTLGKRFGIQGFPTLKWFDGVSDTPHEYSGARSLDDLASFVEQKSMVKIRKKWSAPSAVQMLND</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIH1</accession>
    <name>A0ABR3YIH1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Imidazole glycerol phosphate synthase hisHF</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="9">Glutaminase</fullName>
                <ecNumber evidence="9">3.5.1.2</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="9">Cyclase</fullName>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="12" type="primary">HIS7</name>
        <name evidence="12" type="ORF">Cpir12675_006640</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 9">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>L-glutamine + H2O = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the HisA/HisF family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">In the C-terminal section; belongs to the HisA/HisF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.2" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000339">
        <property type="protein sequence ID" value="KAL1887224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004132">
        <property type="term" value="F:dCMP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01748">
        <property type="entry name" value="GATase1_IGP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04731">
        <property type="entry name" value="HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00278">
        <property type="entry name" value="HisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004651">
        <property type="entry name" value="HisF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050064">
        <property type="entry name" value="IGPS_HisA/HisF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014640">
        <property type="entry name" value="IGPS_HisHF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010139">
        <property type="entry name" value="Imidazole-glycPsynth_HisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00735">
        <property type="entry name" value="hisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01855">
        <property type="entry name" value="IMP_synth_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21235:SF2">
        <property type="entry name" value="IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE HISHF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21235">
        <property type="entry name" value="IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE SUBUNIT HISF/H IGP SYNTHASE SUBUNIT HISF/H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036936">
        <property type="entry name" value="IGPS_HisHF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51274">
        <property type="entry name" value="GATASE_COBBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5 9 10" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="3 9 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="11">
        <location>
            <begin position="8"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR036936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1887224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="550" mass="58812" checksum="F0E1F7BE26FF24A2" modified="2025-10-08" version="1">MSSNKVYLLDYVAGNIRSLVNAIEAVGYSVEWVKTPDDVEKADKLILPGVGHFGHCLTQLSTGGFLEPIRKHIADGKPFMGICVGQQALFEGSEEAPGVKGLGIVPTTLKLFDESSKSVPHIGWNDATTGGLSMYSLRPESKYYYVHSYMAPYVPGQLEADGWTVAVGTYGNESFVGAVAKGNIFATQFHPEKSGVAGLRTLRDFLSGAGPATLARSAEGFSPELFRDSLTRRVIACLDVRTNDQGDLVVTKGDQYDVRDKADAGGNVRNLGKPVEMAKKYYEQGADEVTFLNITSFRDLPVADVPMLDILKLTSETVFVPLTIGGGIRDTVDVDGSKVPALDIATMYFKSGADKVSIGSDAVIAAEEYYAAGRKKSGSTAIEQISAAYGNQAVVVSVDPKRVYVTSEAAAAPHHVISTATPGPNGEKLCWYACTIKGGRETRDLDVVQLTQAVEAMGCGEILLNCIDKDGTNSGFDMELINQVKGAVRIPVIASSGAGVPDHFADVFEQTATDAALGAGMFHRGEYTVKQVKDCLKGKGFQVRQFEAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL58</accession>
    <name>A0ABR3YL58_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">KAR3_1</name>
        <name evidence="11" type="ORF">Cpir12675_006008</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-14 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000241">
        <property type="protein sequence ID" value="KAL1888854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01366">
        <property type="entry name" value="KISc_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KLP-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972:SF45">
        <property type="entry name" value="PROTEIN CLARET SEGREGATIONAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 7" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5 6 7" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="10">
        <location>
            <begin position="621"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="59"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="262"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="638"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="384"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="478"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="88"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="112"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="150"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="174"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="279"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="713"/>
            <end position="720"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1888854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="966" mass="107312" checksum="3A6FED3A6A6E21F2" modified="2025-10-08" version="1">MNIPAPRQDFRMSRSAIPRLPSLSRFTAPDSKLQELTESQSNIRTQALSTMPQPASKIAIKRELPQPATVSKRKALSDKALEYPSRTLMPSSSSRPNITGTSLIGASGLKPPSSTRMKPPSTSLAAKSLGSIRTAHPLAERPGPYDRPKTAQSTRLGPRTRSQTAGRPLTSLSAREEPTAPEPAETKHGMMPSVSPPQLSAAVSNAAAPERKLTAPAIAPNTLHVKPRVSSLNQRFATLSLKENKNNSFANRMAALQENSRAVPNTMGPPPVKPSARRLVPDPRTPERRSIRTSEVAGMAAQTPNALQLSAKVETLHNALRSIAKGNGAVSPCPTAFLTKESNTRHYPAFDVDNRLVNIEQQFSQLKDALNDTVSDRSAMETTIAMLKSRISDQDGEREKYERRAADLQIDLDKCRDETSKLKRQLEEQEWKHKTEVETLSRANKHAHEDFERLAKKETDCLTAKHQEEIDSIKRQHTNELELERLEKSREIDELKAKLENRHKDITTLVSKKEDEIKDLRAQVEILKSEVVLGQSVKTSLQANVTELSGSNATLEAKINSLRSQIEFLESDNKAQSDSFASMETKLQEAQLKMETAQKKLMKEETERRILFNKYQELKGNIRVMCRVRPAIDASEGESAQIEFPDSEQSSSKISVMGPEERSSLGQVSRKDYPFEFDRVFSPAVNNEEIFDEISQLVQSALDGFNVCIFCYGQTGSGKTYTMSSTDGMIPRATHMIYETVTKLKEKSWTYSMEGSFIEVYNEELNDLLTPADSKAKKLEMRHDDVRKQTTVVNCKAVELTSAGRVESMLAEAQNNRSVAATKANERSSRSHSVFILKLFGENSATGERCEGTLNLVDLAGSERLKHSQAEGERMRETQNINKSLACLGDVIDALGRGSAHVPYRNSKLTHLLQYSLGGNSKTLMFVMMSPLEAHLKETLTSLRFAAKVHNTHIGTAKATRKLRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLM0</accession>
    <name>A0ABR3YLM0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Golgin imh1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">IMH1</name>
        <name evidence="9" type="ORF">Cpir12675_005979</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000238">
        <property type="protein sequence ID" value="KAL1888935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051952">
        <property type="entry name" value="Golgi-autophagy_related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000237">
        <property type="entry name" value="GRIP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23157">
        <property type="entry name" value="GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23157:SF25">
        <property type="entry name" value="GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01465">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00755">
        <property type="entry name" value="Grip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50913">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GRIP" evidence="8">
        <location>
            <begin position="1023"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="444"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="878"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1003"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="200"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="284"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="518"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="657"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="74"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="116"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="473"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="485"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1004"/>
            <end position="1026"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1888935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1080" mass="121404" checksum="0DFE5D276B50E145" modified="2025-10-08" version="1">MKALSDQTTSISPNVVPTCQPSTPLTKVASAVHRPRKKPTENFGDNNTTANPDPSVFEAAFLLDNDSEELKQPHLSNSNVVMDPQSTPQDHDVGKTSVERVSHDHDEKPSDARSIGKSSTVSKSEAGSSTELPIEVRTKLRKLEKIEGAYTELLRSYRIAHGRATSIEPFEQVLKENTPLTSIRDPEAFAEYLNQANLKSHILMEELKRITTENDGLQKENAMQADQLKSLNAELTTTQGKLDEKLSAKDNNTNAKADVDDSNQNSEELFSFDSEIEDTSSAVLVALRTRISNLEAKVDIAKQATLLAEQNLEAAEKSHSTSLLELSEKVKSLTLELKSKEEELSVTSTNLSKLEDQLKASKSDALATHDHDIGEINELETKLAISSDASESLQKEFDTVTATSNTLKATVADLKGNIDELKLAKKVDEARIAELEVKISAVTTENEATPESGVPIQPLAVPPQDKAQAAAGKSKKKNKKKKKNGATSLALPSSSAAASPIPSQPVSPVPTPIPAVSVQGLTAEITRLEAEVASKEHQIKRLTKQHKDTETLREEIEILRDELLEIGQEHVVSKAKIKELSQERDSLRTRIKELEEHMSQGGELQEEFDKLKVEHDELKSSSDSLKSDLSVTQSLAQKRFKELTELHEVLQRAQPELKSLRQDSEALKSARAELIVKTTRITELEKREKDVRSELTRTQRISADRESEIKALRERLASDEKTRLRLEDSQRIAGRDLRRAQAEKIEIAAREEKASRDLQKIQQEIQKLRPTVQDLEDQVEKLQREKESYKSEVDLKTKQYVNVQSLVSSMRDETSELRVQLREAQSQAESVGEELVEVQRLLNERTREGETMRRLLADVDERADNKVREIRTRLEAAQEERDRIEDESSALARRKTRETEELKKKMRDLERDLKHLSTENEELKSHEDEWRHHREKLESAESGAVQDLKEMQNAVSELRTALEASEKQLRHAEAKREEMRQLLDETKQRFDRTMRDLKAAQLRLGSSTSRTSIDSTAPNSAPTSNGAADAMYIKTIMLQFLEQKDAKLRSQLVPVLGRLLQFNESDEKKWMAAVQGLGNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLX3</accession>
    <name>A0ABR3YLX3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nucleoporin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_005819</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NUP186/NUP192/NUP205 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000219">
        <property type="protein sequence ID" value="KAL1889356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021827">
        <property type="entry name" value="Nup186/Nup192/Nup205"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31344">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31344:SF0">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11894">
        <property type="entry name" value="Nup192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1889356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1652" mass="185129" checksum="69448CA98F0660B9" modified="2025-10-08" version="1">MTDVKRLEILTQLHRDLLALAEGDLDYTDILFSDACLALFESELEIFWMNAGKNDKSRATVNAGEIEFNDQTFQLNDQFKKDALALADEANIDEVAAVHYMLESQDDIETMDQPLLELALIRLHRTRNFVLDIARLFVDINNSLDEEEFSEYVNQQIFADGSKRVVPRCSKAMIALKTNIQGINEKLTAASVLANGNNKNNLADDSFQTIYFIRNSLYNQHQLVAHIMSRAIDKRKSESQEFLNLLADLKITDKYDALLIHKIPVLGAFITEYASTEGRNDVELARKLNPSVIPNSDAPWSLRGLQATVKAWWIAEYGGHFMGTQPDPADEAQFELEEKKRASDFIEALKDGAFDFLLSVASDIRSPDWQDPARKGMRQWLQRRLPALPSNSVKFPDYFQVLLMSRFEIFVDGFISNLPDVIRKLRTDEDEQRQMSQAHEQDLDLERFLIIIAYAYEGRPEAAMNFWTDPDSNLAGFMQWASRRASTPLVTAFCEMLQAISANEECATCAHQFLLDEGSSSTSRLRKSLSLTWNQIMKELIFFTNKIREKPAPTPPAYRHGKPVANPMDIEPESAMMLECYLRLTTRLVSQSEEARNFLLKDPTFNLVEILFQLASNPVPPRLRACVFWTLDALMTSRSTDNASVMWVCLDAWITGAYTPLALSGTHKNQMLPTSLASAERILEEISQGFEEPQAFITLLTTLVTPVDGAGPIRDTLAFPENLGASYRTPGIDLFVDYVIGKVFSNKANELEDDNQKRLIRQKCLEFCIVCLQSFNQNLIELANVTSINVDSAMGASSLEAYVKTHPFGRIMEWMMNEKVMSTIFSILHESPMEIGNSSPDSPLIQGIHNAITLLTFVLEEQPVFVNIVRKFIQKNQSSSHSQVTTTRYASFDDCLVGHLSLVVDLGLLCGIAPTDVVCASLCLLEKMSASQKIVSVWSSGSGGYVSHRNKAIVAMEADGDHEKIIGYFHDIFKASMDERLEDKTDAYIVKMSALEFLHECLLSSPTKPTIAHLLLGFKCHADSVSIDPKGAFATRKSLFHALLNVWAEIPFGGPDNVRGWLTSMKTKALMILKLLWSSPLTSEIVLDDLRMGSFAFSLLQHNMIIDENAKWEGIETFGYMFTLSRSAETFSDFLAHRAASLDYISRELCYLSQTKLPTYQRRLFDALKGNLYNDSGEIEEVPSIFDMFDFLPNGAMPEIDEPKPCFFANVTFNAAEVPNPRQPELKVYDDTRAAEILLLKRGEKKDEYALITAQEVDAVEAEQTQILDYLQHTNTTTEALWRIKDVLKKWADLVLVILESNDFQGTARTTLYLQTLQTIMSHLEYHAGDKPDTAVPLAQLAKVLLFKLDSVSKTEGTADSESSELGDLVSDKLYQLFQASLDSISCYVPESGLRATYYSICYRYATHIASSSSDSAGRRQVLSTIVTYGERFINFICDDACDGDSSCQIAALILLDALVNVSREEFDLSLIEALINVNFVSILIDSLSTILTDNETTAVDKRGEQENVLDAKLSLLLSLCQSREGAKHVFHANLLRNIDVSGLFSVDPELHVDQADSEAMARHYSLLARMTHIISAAIISRGSQYIASGRQFICKHRMLIMHTLKRSAGIGQVGSGLEDVVMDLADAFLVLISATDFVNVSFTFSLILACP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLX7</accession>
    <name>A0ABR3YLX7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">dihydroxy-acid dehydratase</fullName>
            <ecNumber evidence="14">4.2.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">ILV3</name>
        <name evidence="19" type="ORF">Cpir12675_006007</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:24809"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:24810"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate = (S)-3-methyl-2-oxopentanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:27694"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:27695"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="13">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 3/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IlvD/Edd family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.9" evidence="14"/>
    <dbReference type="EMBL" id="JAWDJO010000241">
        <property type="protein sequence ID" value="KAL1888853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004160">
        <property type="term" value="F:dihydroxy-acid dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.80">
        <property type="entry name" value="IlvD/EDD C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00012">
        <property type="entry name" value="IlvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050165">
        <property type="entry name" value="DHAD_IlvD/Edd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042096">
        <property type="entry name" value="Dihydro-acid_dehy_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004404">
        <property type="entry name" value="DihydroxyA_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020558">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056740">
        <property type="entry name" value="ILV_EDD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000581">
        <property type="entry name" value="ILV_EDD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037237">
        <property type="entry name" value="IlvD/EDD_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00110">
        <property type="entry name" value="ilvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002068">
        <property type="entry name" value="PRK00911.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21000">
        <property type="entry name" value="DIHYDROXY-ACID DEHYDRATASE DAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21000:SF5">
        <property type="entry name" value="DIHYDROXY-ACID DEHYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24877">
        <property type="entry name" value="ILV_EDD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00920">
        <property type="entry name" value="ILVD_EDD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143975">
        <property type="entry name" value="IlvD/EDD N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00886">
        <property type="entry name" value="ILVD_EDD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00887">
        <property type="entry name" value="ILVD_EDD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 19" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dihydroxy-acid/6-phosphogluconate dehydratase N-terminal" evidence="17">
        <location>
            <begin position="69"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="Dihydroxy-acid/6-phosphogluconate dehydratase C-terminal" evidence="18">
        <location>
            <begin position="399"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00052865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF24877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1888853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="596" mass="63758" checksum="3D1FAECE6BA8B816" modified="2025-10-08" version="1">MFARCTQLRAQALRATTSAPQRRLFSAAATRFEDAKLNKISATITQPKSQGASQAMLYATGLTDKDMNKAQVGISSVWYEGNPCNMHILAQSEAIKKSVADSGLVPYRFNTIGVSDGISMGTSGMRFSLQSREIIADSIETVMNGQWYDANISIPGCDKNMPGVVIAMGRVNRPSIMVYGGTIKAGCSMEGKPIDIVSAFQSYGQYLSGEITEKQRYDIIRNACPGGGACGGMYTANTMASAIEIMGMTLPGSSSKPAESPEKVAECASVGPAIYNLLKEDIRPRDIMTRAAFENAMILVTVLGGSTNAVLHLIAMADSVGVKLTIDDFQAVSDRTPFLADLKPSGQYVFEDIHKIGGTPAVIKFLLKEGLIDGSIMTVTGKTLKQNVENLPGFPEEQKVIRPASQPIKSTGHLQILYGSLSPGGSVAKITGKEGLRFEGSARCFEAEDDFIAALERGDIKKGEKTVVIIRNEGPKGGPGMPEMLKPSSAIMGAGLGKDCALITDGRFSGGSHGFLIGHVTPEAFVGGPIALAKDGDKIIIDAEKRLMDLVIPEEEMAKRRAAWKKPEPRPWAQRGTLRKYSMLVSDASHGCITDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMB3</accession>
    <name>A0ABR3YMB3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">LIM zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_005932</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000232">
        <property type="protein sequence ID" value="KAL1889047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08368">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24205">
        <property type="entry name" value="FOUR AND A HALF LIM DOMAINS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24205:SF16">
        <property type="entry name" value="GH01042P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0440">LIM domain</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="7">
        <location>
            <begin position="741"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="7">
        <location>
            <begin position="837"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="7">
        <location>
            <begin position="900"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="151"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="263"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="692"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="61"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="89"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="181"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="312"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="429"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="443"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="483"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="547"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="574"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="612"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="635"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="964" mass="104510" checksum="4D122BD270138B49" modified="2025-10-08" version="1">MFKSGSQHRRKVTPPSPTYMKDDQFAAYLADLRNSRQARPAGARELPADLRQSRNRMSMGSTATAATSSSTSGSSASASPSIAADQASFAQSRRTAATDASTINGSVLSRYSTSSQAKDYYPSKPASPLRPSEVVPSTTYIERGSRWMEKEEAHSLRQAMEALDMRDSGRQSRKSTPPTPTASAFAPPASAAMVSGSIAASLPRETEEDERIYNSALHEASELVWQHENGVVPNPDAPYAYRPHMRKDSYAHARTAAAGLYGDDIAPSGLARDSVRSRSVSNSSEESDYQTSRRSRSSSESARQGIVVADESSVSPTDYTHGQRTPSKSYSGLNSGKYAPGPRRRSSMKRNISGEINRPFSGEQIWEEPESRNQSPAKPVPPPVSNADFPVSTSVSSRPSYPRSIGPRPLDSGINARPLPAPVKPFQRNTDEPLSRVEIHRNPPSQSRNPMYTQSSKLGSTPSSSSATPSPPPPSKTTPVTDVSRKNGVEIRSDDVRNATRIRLQKDRKIPTPTAVSDNPGRPIVSFDANWTPPDESTDKRLGNGWSSPPSSTPSIPAIAIEGTGMSDRRDGSITATKYNSDPVSGSSPTPYTPRQRSTAPDYQPRPPMATPSISLSPEPSSSYGPPDLNVTPASSTIPSISIGSDNSPSTSTSITRSSVPSISVSADVPLINISNDDTPAINVSSVPAVVAPSNDGPSESKTPSVRPLPTPTSAGGARALPRHPRHHWSPAPGSIRRGMTLCHECGLPIEGRFISLAGSREKFHPTCFACYSCGTNLEALEISPEPENARALRLERIRLRNTGHLVPDEPGKTAIDDGDDRLRFFCHLDWHEQFAPRCKHCKTPIIGEHMVALGSHWHYGHFFCAECGDPFEQGMTHIEKDGYAWCVRCQTRRTERRAPKCKKCKLAVIGQYIQALGGEWHEACFRCATCDGSFDDGQIFPVPRDNDAVAVLCTQCRMRELKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNC0</accession>
    <name>A0ABR3YNC0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 16">Serine/threonine-protein kinase Tel1</fullName>
            <ecNumber evidence="4 16">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">TEL1</name>
        <name evidence="20" type="ORF">Cpir12675_005820</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 16">Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Associates with DNA double-strand breaks.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Chromosome</location>
            <location evidence="16">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 16">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the PI3/PI4-kinase family. ATM subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4 16"/>
    <dbReference type="EMBL" id="JAWDJO010000219">
        <property type="protein sequence ID" value="KAL1889357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05171">
        <property type="entry name" value="PIKKc_ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038980">
        <property type="entry name" value="ATM_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044107">
        <property type="entry name" value="PIKKc_ATM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021668">
        <property type="entry name" value="TAN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37079">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37079:SF4">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11640">
        <property type="entry name" value="TAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01342">
        <property type="entry name" value="TAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="16" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="16" id="KW-0158">Chromosome</keyword>
    <keyword evidence="9 16" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 16 20" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12 16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 16" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="16" id="KW-0779">Telomere</keyword>
    <keyword evidence="7 16 20" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAT" evidence="18">
        <location>
            <begin position="1719"/>
            <end position="2346"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="17">
        <location>
            <begin position="2450"/>
            <end position="2761"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="19">
        <location>
            <begin position="2776"/>
            <end position="2808"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU365027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAL1889357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="2808" mass="313797" checksum="2609D20E38791DC6" modified="2025-10-08" version="1">MAPENSSINGILAAISGTAQKARASGLDDLLSLMDKSKSLPQLTDKQYHRVFETLFQCTIAEKQQNVRKSSSTATAAGLRLGKCAKAVRLTYEHAFGALKRKTILAVIDHITQTLESSDGTLVALPNLVSEYLRALVSILSNSCTVEQLARDHSEGWLTCTGFCVEVIINSLSEVELDIESSTRASSHPVSSSGSVFSSRPGHRIALQGMAINVADLQLLLECLHHLIVPPIAPIKDLVDKITSAAIHVIHLRHLAFGRIPQDIFAVLSVLMTRLQADNIAKATSITQNVLPHIRYWWQPDKPEKEETVRSARDEILKTLFSMQLHLQYISQNEASTQFCTHIEDLLDTLWEEYSQRDEKCRLQLGDVSFRSSRIPKDYFQTPLFYLYYRGLDLISSADSCAEISSITTNPDVNGPTIVIDSSLLLMLCLLRLRNSRAPNASEMTCSQTIRWVFSKWNPDDIAFAYSRSCHVDPSDVANLLRACCGAGPLKEVHVNTLPGGGLGQAWREQFKIQHVTRHLTLLKEPAKLQTRQSLNETSSQSFLAQSSNQVASFAARKLTLDLFLPKMTTLQDMCTLWSKKVADGGLLIHPEMVHSLFSTCITLALMLPLLKEINGPDISTLEGSLKALIDASFKAVTRAVDNSSFFSVLIRAIRPHLPTLTTEGLRSLRYGQPELLDLIRKLNEAVHQRYANMRNEMSHDFMDLDDDFESQKGNSISQLEEVIAPRLIEEVGFRSYSFQLETEVRLQIIKFACHSREALKELPTSFTDYLIAMPDSNILACRDALIELFQSQIRFRDSGIIEIVEKVGSIMSQSSYDCCEVALTTCIDTINGLLPVWKSDKSDLAAMVGDMYFHIVKNGLKMNMLSSSAQISLAKLLLRLIEEMPDYADRLSLASCQSTLLHIQQKGDMAVKFYIGQRLPEMVGFFVLKSHDDIFNSVMETLPTSADFIEGIAYRLYVLSELACHWSTLLRRCIYHIFETPGMIPNSANYAQRGLEKVSQALNLTSPQDLFGLFAPQILYTWFPVNSVDDMPFSIFGFNSLYDLLMACREEASGILIMRGEEATFEEFAARVNMTPKQLILENFGKIIAYSVANGIAKQRSRVNRDSNASDSGVYDGPKTQSKGELYLRKVLGDQTFLVSVYSGFADAVSILMDIFDQEDPVELSFVSGLEYAANIMAQIKSYSHSSVLIPPNQQPLFKGKHLVRQLNHLCTLTPKYDVLTMWTPPLVVYVARRLINTIYPALGSFHACSVLRKLRVLVCLCGDVALQYHPLEMLLFSLRPFMTDPECADDAMGLAQYLLVKGVEYLKSVPSFLAGFGLSTLASLRVFLESSQFSTTDKYQFHETLKKTRAFHSWLNTYLTGYLDLGEFAEEAQKEAFQIITQSAARICSSGNAEKGTHESNLLLEILRDEQRQRQVLSESARNLALGLLCGNFKLPKSSAVDIISTDDDAVKFAAVVCKTCKTSSMSKSKEYLSWAGQVAGRSFAASGTVPKIFLYESRLPEYEKVSPDFVGSDKALLVLLRELSSSEGSFTAGLAEGAIRRIVSDAGSTANDTLSKVCEEALSKSLYWSSHWKEYYAPSSETPEVNPKLDPLAFSAEAIERANWIQRMALNLCLCATDKVVISAVAPVVKNVRGFAEQAFPFILHLTLLSQYDTGQVIKKTFSDAIRIWFNSPVSKESRDNISLILNAILYLRTQQPPNGVSMVDRMQWLDVDPNIMAQMAVECGMHKSALMFLEGTTSKNVSTSRSSSSFAVPQPQDAPSQELLLNIFENIDDPDAYYGISQASSLSSALARMEYEGDGAKSLALRGAQYDSHLRKRDPLASQDGQALVAVLGSLGLSGVASSILQNQSNNVASKESLDSTFQIARRLEQWNLPVPVASTSSNATIYKVFQGLYQATEVDISRSYIQDGFSETMSLVTSKENNSTTLREHLRSLAVLTELEDVLSMTRSTDLSSLPSHFYRRKTWMRSGRLVYISLFLATILTINTLCRYDDVSNILSCRQTTFGLLSQLPLLRNIVNISASDARKLEVHSLLLSSEIYRFHKAKQESLNLSTSLSALANPCNNLGLNIDAAIKVEVANSLWDHDEMLSSIGILQTLSRDSNSLKTQSIPISLADVLSRLGHQVSVARLENPDEIQKSYLEPALRELKGRSEGKDAGKVFHQFAIFCDEQLQNPDMLEDLERLKELEKGKAEEVEQFEMLIASTRDANSKRRYQAHQGRARRFHMLDKMELQRLEDARTEFLRLGVENYLLSLIASDEHNNDALRFAALWLERSDDDSINAAAFKHLSKVPTRKFATLMNQLSSRLQDLSNAFQELLTDLVKRICIEHPYHGMYHIWSGTKSRANKRDSVAVSRITATHQVAKYIETHPSIASVWQSIDRTSQSYDLFAAEPTDKHKTGARISLKSSKTSLRLIQSLNKYRIPPPTMHLEVRADRNYSQVPLVEVLEPYMRIAGGNSAPKVITAIGTDGKRYKQLVKGGNDDLRQDAIMEQVFAAVSSLLKRHRATQQRNLSIRTYKVLPLTPTSGIIEFVANTIPLHDFLMPAHQRYYPSDYKSNHCRKEISLVDSKSVDVRVKVFRKITANFRPVMRFFFMEHFMDPDDWFARRLAYTRTTAAISIVGHILGLGDRHGHNILLDTATGEVVHIDLGVAFELGRVLPIPEVVPFRMTRDIVDGMGITKTEGVFRRSCEFTLDALREETYSIMTILDVLRYDPLYSWSMSPVRMAKLQDAKKEEVDKDAADIGADGRRKNGLVSEASEADRALAIVRKKLSKTLSVTATVNDLINQATDDRNLAVLFAGWGAYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP00</accession>
    <name>A0ABR3YP00_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Coatomer subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Cpir12675_005727</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Golgi apparatus membrane</location>
            <topology evidence="1 10">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000211">
        <property type="protein sequence ID" value="KAL1889605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22948">
        <property type="entry name" value="Coatomer_WDAD_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006692">
        <property type="entry name" value="Beta-prop_COPA/B_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047312">
        <property type="entry name" value="Coatomer_alpha_WD-assoc_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016391">
        <property type="entry name" value="Coatomer_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010714">
        <property type="entry name" value="Coatomer_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050844">
        <property type="entry name" value="Coatomer_complex_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056176">
        <property type="entry name" value="TPR_COPA_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876">
        <property type="entry name" value="COATOMER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876:SF1">
        <property type="entry name" value="COATOMER SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04053">
        <property type="entry name" value="B-prop_COPA_B_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06957">
        <property type="entry name" value="COPI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23953">
        <property type="entry name" value="TPR_COPA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003354">
        <property type="entry name" value="Coatomer_alpha_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 10" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <keyword evidence="4 11" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="53"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="95"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="137"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="212"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="256"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B second beta-propeller" evidence="13">
        <location>
            <begin position="351"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B TPR" evidence="15">
        <location>
            <begin position="623"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer alpha subunit C-terminal" evidence="14">
        <location>
            <begin position="853"/>
            <end position="1223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="844"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="861"/>
            <end position="875"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR003354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF06957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF23953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1889605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1225" mass="136285" checksum="C394FD40FA720DC7" modified="2025-10-08" version="1">MSTTSSMLTKFESKSSRAKGIAFHPKRPWILVSLHSSTIQLWDYRMGTLIDRFEEHDGPVRAVDFHPTQPLFVSGGDDYKIKVWSYQTRRCLFTLNGHLDYIRTVFFHRELPWIVSCSDDQTIRIWNWQNRSLICTMTGHNHYVMCAQFHPKDDLVVSASLDQSVRVWDISGLRKKHSAPTSSFSFEDQMARRNQEQADMFGNTDAVVKFVLEGHDRGVNWVAFHPTMPLIVSAGDDRLVKLWRMSETKAWEVDTCRGHFQNASACLFHPHQDLILSVSEDKTIRVWDLNKRTAVQSFKRENERMWVIAAHPEINLFAVGHDNGVMVFKLERERPASVIHQNSLFYITKDKHVKSYDFKKNLEGPTLTVLKKLGSAWTPPRTMSYNPAERSILVTSPADGNSYELINLPREGSGALESPDSKRGPGNSAIFVARNRFAVLDVAAQTIEIKDLSNNVTRSFKPPAGTTDIYFGGTGNLLIIAPSAVYMYDIQQKKVTAEHPINGVKYVVWSNDNRYVALLSKHNIAILSKSLEHLSGLHETIRIKSACWDDTGVLLYSTLNHVKYTLLNGDNGIVRTLDQTVYLVRVQGRNLYCLDRNAKPRLLPIDPTEYRFKLALVKRNYEEMLHIIQNSSLVGQSIISYLQKKGYPEIALQFVQDPATRFELAIECGNLDVGLEMARELDKPQLWQRLGTEALAHGNHQIVEMCYQKQKSFDKLSFLYLSTGDHNKLARMAKIAEHRGDFTSRFQNALFLGDVEDRIQMFKEIDLYSLAYITAKAHGLEEECQAILEASGLTEEEINAPAIGGSLSVPKAIVPTHAANWPTKASSQSVFEKALLGQVEGLSLEDNQPTGDLMDVDGDDAATSKAGAGAGASAALEEDDDDAAGWDMGDDAVPEIEGDFVNVETAEAGGSGLSEAEMWARNSPLAVDHVAGGSFETAMQLLNRQVGAVNFAPIKPRFLEVFSASKTYLPASSGLPPLVNYVRRTFEETDPRSVLPIVPRDLEHLAAHDLQRGYDAMKANKLEDGITVFKGILHAILINAVSSEAEVAEAKKLVASAAEYTVAMGIELSRRSLGAPADIAENPALLKRSLELSAYFTIPKIEVPHRQLVLGAAMQQAIRTKNYNSALSFASRIIANGGSGKIVENAKKTKAQCERNPNDAVEIDFDQFAEFEVCAASHTPIYSGSAFEECAFDGSKYQPKFKGQVCRVCEVCEIGKHGSGLKLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP76</accession>
    <name>A0ABR3YP76_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein mL50</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_005671</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL50 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000207">
        <property type="protein sequence ID" value="KAL1889693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018305">
        <property type="entry name" value="Ribosomal_m50"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10501">
        <property type="entry name" value="Ribosomal_L50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="64"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="391" mass="43525" checksum="78FFE414DFA84DF0" modified="2025-10-08" version="1">MLLPNTIRRLPRALRICANPAAASKATVSISALRSISTTPSRHIQPNNRLQAIFGKGSAGEEAKAEEEAKRRELLTAREKERNEALAQAAQLDQQQLVSGDELDGFAESKLVVPGEYLVAPTPAEAEQMAYVPAEDASGLESVGNLDSWWDNDGHWGPESHLTVFAAPRSCISDEVMMVLVRQAVVEALVYRAKGEATGMTQRWARVNKEVAYKTNQITFEVKEGGDVALTGEISEVYEALNSSNAVTAEEESFSQEEAAEMVKTFDSTWQQISLADPVLKFAISKRIYQLTGYLISDSRLYLSHTVGQLLNYLITPPKAKTVNQQIRSSETLKSLPNVRVFSRRITPIDRQIMDGSWKKIEEELRKRKLPIIGHEELGDFAERKWLNIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP91</accession>
    <name>A0ABR3YP91_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="8">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ARO4</name>
        <name evidence="11" type="ORF">Cpir12675_005673</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>D-erythrose 4-phosphate + phosphoenolpyruvate + H2O = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the class-I DAHP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000207">
        <property type="protein sequence ID" value="KAL1889695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006219">
        <property type="entry name" value="DAHP_synth_1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00034">
        <property type="entry name" value="aroFGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009395">
        <property type="entry name" value="PRK12755.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE DAHP SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225:SF12">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE, TYROSINE-INHIBITED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001361">
        <property type="entry name" value="DAHP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP synthetase I/KDSA" evidence="10">
        <location>
            <begin position="50"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="368"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR001361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1889695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="382" mass="40970" checksum="4C1B75A514103161" modified="2025-10-08" version="1">MPGVYEQESAAADDTRVLGQDPLIQPALLAQEVPMTKKALDTVLKGRHESSEIIMGRSDKLLVVIGPCSIHDPATALEYCQRLKEVSDKLSGDLTVIMRAYLEKPRTTVGWKGLINDPDIDSSFKINKGLRVSRQLFSDLTSAGMPIASEMLDTISPQFLADFISVGAIGARTTESQLHRELASGLSFPVGFKNGTDGNLGVAIDAIGAAAARHHFMGVTKQGLAAITRTKGNEHGFVILRGGTKGTNYDKESVQSAKDILTKKGQKQAIMIDCSHGNSNKDHRNQPKVASVVADQLREGETSIIGVMIESNINEGNQKVPAEGPSALKKGVSITDACINWESTVTVLEELAESVRARRLAVKAAGEAQNSNKNQVSALEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPH7</accession>
    <name>A0ABR3YPH7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">KIN3</name>
        <name evidence="12" type="ORF">Cpir12675_005641</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000203">
        <property type="protein sequence ID" value="KAL1889844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08217">
        <property type="entry name" value="STKc_Nek2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051131">
        <property type="entry name" value="NEK_Ser/Thr_kinase_NIMA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899">
        <property type="entry name" value="CAMK FAMILY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE NEK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 12" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="14"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="383"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="520"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="675"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="294"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="553"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="597"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="618"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="690"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1889844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="731" mass="81098" checksum="5FA0EB519A1BBC15" modified="2025-10-08" version="1">MASSNPTVTKAEDYEIMDKIGHGSFGIIRRVRRKADGLILCRKEINYLKMSQKEREQLHAEFQCLSHLRHPNIVAYYHRDHLKETQELHLYMEYCGNGDLGRVIKDLASKGQRASEQFVWSIFGQLSSALYRCHYGIDPPSPSDGTSNPEKAPAGTLCIMHRDLKPENVFLGENNSVKLGDFGLSKMIKSQDFASTYVGTPYYMSPEICAAERYTLKSDIWSLGCIIYELCMRSPPFDARSHYQLVQKIKDGQYPALPNIYSSELRDAIDACLRKSPDARPSTHDLLHLPQIRLTRREMELAELKRKLRAKQDALAQKEKELNHFAGAIETEKKLIRQEIDSQLRREWEARAQLEISRHINLEVENLQKQFETEVRARVEAELKRRESLSGPQRTATPEPEAKKSPISSVQDQLAVTAISAPVAESLPSEATAGLTKRNMSTPLKRAHTMYPGLNPETPGDIEMVSPSPMAISSLSLSPRRNGTTKPPTNNVNIFQHNKAAAGSGNGLAWEVPRDAVNIESDDEEPPASPTPAVRSNRNPFGKNRPVLLAQKSAPNRNLSIPTLASKNSNSELPSVSPSRRLSKIPSVTSLHNAKLSSGSSSSGSSSDTNNIHGSPTRGKKLVRHQHHHSSGDEERLGKVLAKNNIKGRTLVELQQARAGGRPLSAVLPSSAVLAAPSSSTGENVSPKRAFRDRLTAAEGNSRRSSDPTVWDPEVDEMPSPFLQKTRQVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPV4</accession>
    <name>A0ABR3YPV4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Fork-head domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_005556</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000197">
        <property type="protein sequence ID" value="KAL1890015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045178">
        <property type="entry name" value="Fhl1/FHA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21712">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN FHL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21712:SF29">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN FHL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fork-head" evidence="6">
        <location>
            <begin position="1209"/>
            <end position="1283"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="3">
        <location>
            <begin position="1209"/>
            <end position="1283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="37"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="515"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="684"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1138"/>
            <end position="1198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1374"/>
            <end position="1413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1430"/>
            <end position="1469"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1672"/>
            <end position="1739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1876"/>
            <end position="1969"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1982"/>
            <end position="2009"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2181"/>
            <end position="2208"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="990"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="78"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="103"/>
            <end position="134"/>
        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="194"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="235"/>
            <end position="245"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="521"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="689"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="730"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="781"/>
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        </location>
    </feature>
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        <location>
            <begin position="875"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="904"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="929"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1146"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1165"/>
            <end position="1185"/>
        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1385"/>
            <end position="1401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1430"/>
            <end position="1463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1672"/>
            <end position="1689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1699"/>
            <end position="1710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1723"/>
            <end position="1739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1876"/>
            <end position="1907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1909"/>
            <end position="1920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1921"/>
            <end position="1955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1982"/>
            <end position="1991"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="2181"/>
            <end position="2200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1890015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="2208" mass="232825" checksum="272F361ABBDCE171" modified="2025-10-08" version="1">MTSTQMQMTVAGPAPVAMSQVAVSDSVHHNIMHHHNRSLSGQQSTSHAGHHDSNFDDDEQVPMDIDSDSSDEPEPRPRPAPSPLDPPTAPTFSAVSAPAPSNAHPPPPPPPPPPPPPPPSSLPPPPPPLPPPLDGPSQSQPEDTEMEFPSQTRLRASTPMAKSIDDKKPLAPIQASGDAPHTPKQPEPTAKMQGPSTSSPTQPELVTAKADTSDKDLIDAPSTSGEDEITTAPLPSTPSPTPGSVPVYSPDPAPAAVPIDVPSSKPTLDSDAAVLDVAASATPMQIDDNSLLTSAADSNSLEMLALSIPRTPAAFAHHAAVSMNGIMNPSMNISSLNTNRSIFQALLSASSSSHPHVHSHMRTHPRGTLNPSATVVPSEVNFSTQDLDMASSSNAVSYSQFPPLRHPRRTMDSSGLESFARIEFADSTFQMTTYSIIIGRDQRALRQARKDETRALERQRLKDDYSLQGLDPPSEIMEDRKFSKSYVSEEGGMLGPESDGEYTDRPTKRRRLVGNGACGTASGTVNGSPVPENSSSENIISDRQYVSHTPGAAAVDLASLRPSPDHVPFLGIHSPGPNIAMKTKAISREHMKIQFNKKDHVFEAIPLHKNGFFCEEVLYRDEKVVLRSYDMLQIKDVSFTFIINGVEQGCTGAEDVEDEQTLRRRYSEGGKEMSLDFEASMANADDSSDQLSDLSDVPPDLMDSDSDDKPQPKSVKLAGKTTARKSPSLDSRDLATREEAHNQSFADSPPDPSQHPLKRRGPGRPPKDGIMSKRQHRERKKMLQEQERQKRAEEAEAEAEARAQAEIQAAKEVKAKPQTEAKTEDKEKPQFKAEAQQPATAKLTAKPEVQHVLPEPDDSHIQLQALVEAEPTISVKVPSTPKPTAKPASKPATTPVPVHTPIMLPIPPSQPPKPASPPKPPQSFTIPLPSLPPAAPPTPIQQVQPAVPHLASISVPTVASTIPTTQPVATDMACLDPVNSLSNAPQLDALQLQQQEQHQHQQQLHQLEAQQESQIQQLQLQQQQQQQQQQVQLLQQNHQQQPQQQGQLLLPQASISTAHDLLALQQAQQQQQQQQQQQQQQELHQMAVDLAHLRQAGAQVPAQQQLQLQHLQQLQQLQQQHQLQQQHLPMLLEPEKRKVGRPRKHPLPDHLGDLPEKRKYKKRKSRDEGFFEGSDAERRAREKKEKRSRPKSPPLELKIEDYTPEQLQKPNKNYSVLIDETLTAAGPDGLTLKQIYKRISLNYPWFYFHTETKGWESSVRHNLIGNEAFRKDEVSNTWSRVPGVELDAGKKRKATSPDQGTFPIYQQQHSYQMQYQAGTQQGFQQVTPAQTFATSQPQQINRHAQIYNQATPALVAAQGQAAVAAVGIVPQTQGLAGAPGRVPASTGSVMQPQTSYTSTPSRPGLGHTVAATAPSASAASVPAIAPASHRLPQAAAPAQSSAQPRSQQAASPAAGAVPGTPASQSSASQPRYVLHPRLLEAIAVLKHGLGQNLADAHVQNATDIVNAAVTRFLGITPTETAVINGPMEQICMRGFLGVVNGAIGTIEVGVKTTFPSLPSTATAPNNMALAQTFGLAGRTIIEPHAFLAMENFRQSLPRYLSSLVEANRMDALGISVMIRVLGLSRTTLLKSREGVDPATAAVQAQSDEQLEGGLVNSLRRVLGSMGFVVPTPHATGNTPATTPAAAVGPSPMRTPASQPATTAVPAHTTPMQVPPSTQTQTHVSAPAAAPAAAPETTTVPLPAPAATVSVPTSQAIHHSITAVPATQPVAHTPTPVQHVVGVPATVSPPAPHIATPQASIGQAIPMQVSSVPAPAPAPAPTHTPIPAATLVPTPALAQQAQEQQLPASVPAVAATSASSVVPASVTPVAQAPALQTPMTTASATPSAPVVTAQSQPPSEAPAQPHPQTGVGSNSQPQIESQSQPHLQPQAQAQAQAQAQAQAQAQAQAQAQAPVQPQLPPQSQPTSTGHLVSTNLAVPLAPTPALASTEPPTQTPCPAPAVQTQQQTLTPSLSATSTLAFAQTAVAPTPTALPVSAPAVQAQVVSSLSPAAAALTIAPPTSSTSMTAPTAAPVATPTLSIATPPIATASASDGSAASVNPLSPHPPVLATSGASLLPVVSSPAVAPAPSPAPASVSTPATASVTAQPSIPAIITAASTPPTVPVSAPSLAPTLHAQAADMLAPAPASAPTAIAASTTSAPSPGPAPST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ05</accession>
    <name>A0ABR3YQ05_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ferrioxamine B transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SIT1_2</name>
        <name evidence="10" type="ORF">Cpir12675_005564</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000197">
        <property type="protein sequence ID" value="KAL1890022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF92">
        <property type="entry name" value="GLUTATHIONE EXCHANGER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="332"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="371"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="407"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="466"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="505"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="575"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="99"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="625" mass="67464" checksum="B9FB5A0F11D8AFBE" modified="2025-10-08" version="1">MSPQQAVFDIGPSSTVTPSNLSLPSPSIFDIPTNGIPALENTATVSDNSRKNDFVHSTNSVPPEPSSPLVVAITSSDSAGVVRMKGINAVATPRDKAMLFLGVLVLSWAYGLDGTMRYTYQNYATASFHQHSLLATVNVLRAVIATVAQPTAGKIANVFGRMELIFLAILFYAVGTVIQAASSTMKTFAMGAVLYQIGYTMTILLVEVLVADSSSTRDRVWVSYIPALPFVVNTWISGFIADHVLRTLGWEWGIGMWAIIFPVCCMPLLYVLTSLERRAKRKGLIPPTPKTSLAEYFHKLDVPGVILIAASFSLLLVPLTLAGGAASQWRQAYIIVPLILSVPAFAALGYWDANLAQYPMVPFSALKDRGVWAPLVLALLLNLAWYMQGDYLYTSLVVCFDFSVPMAVIVASLYSFVGTVVGFTNGLLIRRVRRLKFSIVAGTILMAVAFGLMMKFRGSPTSFGKAGIILCECILGFAGALYPYPTQAVLQARLKHEHQSAMLGLYLAMYQVGSASGNALSGLLWHQTLPKLLHKNMPGNAALAVATFQDPIGMSGKFPVGTPERTAIIKSISQVQYHLCIFGLALSGPIIGIAMILRDHRLNDKQTLAEENGGLVDEKTGNTTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ90</accession>
    <name>A0ABR3YQ90_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_005379</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000182">
        <property type="protein sequence ID" value="KAL1890485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF10">
        <property type="entry name" value="ACETAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="3">
        <location>
            <begin position="60"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="558" mass="62036" checksum="B67FB26A367A16B9" modified="2025-10-08" version="1">MLSDYFQHRRLYAAKKAERLQRIRALHASNLLTAEDKETINLPIEQLVCEVHSGTRKPIDILRTYTKVAVKAHEKTNCLTEVMVKSAEKWVNDGSINMKGPLAGIPISLKDTVVVEGYDSTVGYSSFVGNKVPQDGTITKILKMAGAVPYVKTNIPITLLSFESTNDVWGRTTNPHNSKYSPGGSTGGEAALLALGGRIGFGSDVAGSVRVPAHFSGIYTLRCSTGRWPKVGTRSSMAGQEGVPAVYSPMTRTMDDLSYFTKALISTDMWKYDYSIHPIPWRQDAMDQVRTTEKLRIGIMRTDNVVDPSPACMRAMGIVEEALKKQGHEIIEIDPPSPLEGLRIASQLLVADGGALYRSYFRAGEWEDPGAAQMSFLMKLPRVFKFVYHLWVKYVRRDAVWASLIRDWHPKTAFGNFKLVAQREAYRAEWFEWWKDANVDFLLTPPNATPAVPHEGMKDAVSSCGYTFLFNLLDYTAGVLPVTHVDKALDQLPQGFNIKKLNGVAQGAYKLYNATAMHGLPVGVQIVGKRLEEEKVLAAMELVEQALGDNKYQLLEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQF0</accession>
    <name>A0ABR3YQF0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005312</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000178">
        <property type="protein sequence ID" value="KAL1890588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="78"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="108" mass="12098" checksum="9571D1637C5FEADC" modified="2025-10-08" version="1">MENEKAPRDLQNFAQDAHRVVLCHGGIVEVAPLQVYARALIFSPTNSLMRQQYCHEEPSWIQLKPKVEADWNLCLRTLEGHVDKVASAVFSHDGRQLASGSSDEALKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQH1</accession>
    <name>A0ABR3YQH1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transcriptional activator spt7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SPT7</name>
        <name evidence="10" type="ORF">Cpir12675_005334</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000179">
        <property type="protein sequence ID" value="KAL1890581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05510">
        <property type="entry name" value="Bromo_SPT7_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22927">
        <property type="entry name" value="HFD_SPT7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006565">
        <property type="entry name" value="BTP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037782">
        <property type="entry name" value="Spt7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47343">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR SPT7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47343:SF1">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR SPT7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07524">
        <property type="entry name" value="Bromo_TP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Bromo" evidence="9">
        <location>
            <begin position="377"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="83"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="473"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1051"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1096"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="233"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="125"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="159"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="473"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="487"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="502"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="521"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1096"/>
            <end position="1123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1170" mass="127940" checksum="E25C06E3B5B83D87" modified="2025-10-08" version="1">MPFANSSLNRPPYLAVDDGPSRMMTPVDGSGTPAPPASLLPEAVDPEEEQRRAHFANLFRSAESKISQIFGSDGRYDLGLITSLARRAPSPPPTTSSHSQLPPPATDHAPITEPPRKRAKRAINEDDYDDDDDDDDNGNGPSHPTTISSPQNAKSTALSSGPGALPSPSKSGSSPVQSVTSPSRQVEKHRDLVVLLAPSSDPSQSSSSLATTTTSATQLSTTMCATQQKSSSSEDARKQLEAARTATEEAARRSFHTIFYTLENDRTAMLEQQQLEESEKQLQAEMDSHQSGPAVSNAQAQNLGTLSSTNLGASSLTLKHLIARIDMKRDVVNATDSELRLLMNEVRKNRSKWASEENINQEELYEALEKVLTELKAHTEYSTPFLTRVNKREAPDYYNIIKQPMDLGTMTKKLKGLVFKSKADFVGDLNLIWDNCLKYNRDMSHPLRRMANGMRKEAEKLIPLIPDLTVRSRAEVEAEERRKQNGGDEDNGEDSEDEPIMSSRGRAGGTTSTKGTSKARRSGDVEKEGTPAEQKPHIQVNGVLAKAREGSEADGSVRGTPPIAGSQTPIVAPQGDSMDVDGPSLSGLALTHTMGETTQAVYEDEEYKIWKQVTKKGRALITRERYMLFKESSLNPDAPALLRRKADMRRFLRNQKMIDCNASSVRPADAGASSEEPVNTETLVDNMDNAEEEERVVPAYYQPQSLIPDIPPHLQWIEDGEGQVVNQNQWAVKVIEPSVWKSPASKFSQQIDANIRQIQETRKLSTKISVVKQMQVQTQVYSNQFPKAAEPFVEADVPPQFVTDDGPLIAGNLCEKALQRSIGKILYHAGFEELQPSAVDALTDIAADYFQKLCRTFNVYNEADKMQVTLPDGPTMYKPRYTQEEIILHTLDENGYDIATLEAYVTDDTVRLGGKLSQIHERMKQHLTDILRPALTAEAGVDGVGAFNDGSEQFVSGDFAEDLGEDFFGFRELGLDKDLGLDMLSVPLHLLQSRMRSQYQQTQPTGTTDMDILPPYPPHTPVARESLNEEIGLVRNFFLAKLHATNGEPLVEDEDLPIKQRRPRPRLPATGKISAPQKKPLREQIALAKKKKKMEAAAAASAAAAAAGPSSSSGSGSQENSAAKPTGDTTTKAPSRPSVGISMKAGLPAGTPDQGLKPSQMSIAVGGDME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQS0</accession>
    <name>A0ABR3YQS0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005506</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000191">
        <property type="protein sequence ID" value="KAL1890190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="17"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="313"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="423" mass="45295" checksum="B8EBB705A437D814" modified="2025-10-08" version="1">MTATQSSSKSSNSDRNLIIALVASISGGVIIISIILILLYRRKRKFSILNRGISPIDDEEIESWKVSKGDDGIEKETLASSFSGKSIIMKSVPSIYTRPQTPEAAVLRDLPTLSPDDLGLPPSHKNACKRTPSSSIATTLPSIPQEPSTPQRKTSIKANVTKPARIKKPAGVIIYTGGPTTLNEGIFSSPSTSESSPRHKKSMEAPQTPIQARAPNSRPGLTDETVQGDAAYLPSPKRSNTMRISRGHSRGHSRGYCNGHKHSSSLSSTMQRHQRNGSSFSFSSGGIGWKDQWLSYHRDIEAAMDPKSPPLLSSITSASTTSSEHSNTSQSCRSPGVTGPLGFSSSTPTLTLTLSHSRSLSNVKSTGSSLHTRSNQHMRIYSDAAVPPAVSFDFSEGDVILGDLSPRPVGKKPQLQDIGRAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR15</accession>
    <name>A0ABR3YR15_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">dCMP deaminase</fullName>
            <ecNumber evidence="7">3.5.4.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">dCMP deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">DCD1</name>
        <name evidence="10" type="ORF">Cpir12675_005238</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.12" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000171">
        <property type="protein sequence ID" value="KAL1890813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004132">
        <property type="term" value="F:dCMP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01286">
        <property type="entry name" value="deoxycytidylate_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015517">
        <property type="entry name" value="dCMP_deaminase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035105">
        <property type="entry name" value="Deoxycytidylate_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11086:SF18">
        <property type="entry name" value="DEOXYCYTIDYLATE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11086">
        <property type="entry name" value="DEOXYCYTIDYLATE DEAMINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="9">
        <location>
            <begin position="180"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="333" mass="36828" checksum="3ACFCC1481609760" modified="2025-10-08" version="1">MLVGICGGICAGKKTVADYFIRCHGFRLIVLVDKAEPCPEPFDESKPVFNSIDALLNFATIRWREPWVLVGIKDPLVVDILETRPSFLLISVEAPVSESWIRHSHRIKTLPLSATAALSSQATDIHEFIRETDANNYSPDVRSITSRAAIRLINNSPNVNVLLDRLTNHHFEFAQRMRPSWDMYFMSLAALASKRSNCMKRRVGCVLVTRENRVISTGYNGTPRGLCNCSDGGCPRCNSGGSGSGAALSTCLCLHAEENALLEAGRDRIREGSVLYCDTCPCLTCSIKICQVGISEVVYNQGYTMDRDSAKIFSEAGVKLRKFVPPPNTDMYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRK1</accession>
    <name>A0ABR3YRK1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Pyrimidine nucleotide transporter, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">RIM2</name>
        <name evidence="12" type="ORF">Cpir12675_005170</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000166">
        <property type="protein sequence ID" value="KAL1890980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049562">
        <property type="entry name" value="SLC25A33/36-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45829">
        <property type="entry name" value="MITOCHONDRIAL CARRIER PROTEIN RIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45829:SF4">
        <property type="entry name" value="MITOCHONDRIAL CARRIER PROTEIN RIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="52"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="174"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="290"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1890980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="383" mass="41087" checksum="FBFBFA149BC8B626" modified="2025-10-08" version="1">MIAQVLPDPKVRTSDGTSPSTTASVAAAIVPSSANNTNSTVAASKATPSSVSRSWVHFVAGGAGGMAAAAFTAPLDVLRTRLQSDFYKTQLLESRAANGHISTGGILHPAKAAGRHLNETLQILANVWRTEGPRALFKGLGPNLVGVVPARSIHFYTYGNGKQMISEHLNNGSEAAWVHLSAAALAGVATATATNPIWMIKTRLQLDKDTATKQGSVSLRRYRNAFDCAAQVLRSEGISAMYKGMSASYLGVAESTLQWMLYEEMKRRLSLREMRIQARGGERTAWDRVGDIMGKLSAAGGAKLVASIITYPHEVARTRLRQAPAADGRPKYTGLMQCFKLVWKEEGFAGLYGGMTPHLLRAVPNAAIMFGIYEGVLHLFSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT29</accession>
    <name>A0ABR3YT29_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Emp24p/erv25p-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ERP1</name>
        <name evidence="11" type="ORF">Cpir12675_005357</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000181">
        <property type="protein sequence ID" value="KAL1890494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046540140" evidence="9">
        <location>
            <begin position="17"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="10">
        <location>
            <begin position="26"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="145"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1890494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="219" mass="24999" checksum="EFF4270887E73AC4" modified="2025-10-08" version="1">MKAWLPLLALSSVAQALYFYIDGTGPRCFIEELPKDTLVVGHYSAEEWDDNKRSWESHNGISIYISVDETFDNDHRVVSQRGANSGKFTFTAGDAGDHRLCFTPSSTSGRSGWINARDVNGGIRLHLDVTSGETSDLESRDKSKMDDLTSRVRDLNNRLREVRREQVFQRERESEFRDQSEATNARVVRWILVQLVVLAATCAWQLSHLRSFFIKQKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTU9</accession>
    <name>A0ABR3YTU9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">S-formylglutathione hydrolase</fullName>
            <ecNumber evidence="2 6">3.1.2.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_004864</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Serine hydrolase involved in the detoxification of formaldehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>S-formylglutathione + H2O = formate + glutathione + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14961"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="EC" id="3.1.2.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the esterase D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.12" evidence="2 6"/>
    <dbReference type="EMBL" id="JAWDJO010000148">
        <property type="protein sequence ID" value="KAL1891678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014186">
        <property type="entry name" value="S-formylglutathione_hydrol"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02821">
        <property type="entry name" value="fghA_ester_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10061">
        <property type="entry name" value="S-FORMYLGLUTATHIONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10061:SF0">
        <property type="entry name" value="S-FORMYLGLUTATHIONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0719">Serine esterase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1891678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="282" mass="30840" checksum="B17AA57C6850972C" modified="2025-10-08" version="1">MFEIKTTIVASGGRILKLSHASTTTGTPMAVNVFIPPGASRATPAPVLVYLSGLTCTPDNCTEKGFLHQHAARAGLALVWPDTSPRGLDLPEEHTNWDFGSAAGFYVDATQEPWSAHYRMQSYVTDELPAALFAQFTELDGSRVSIAGHSMGGHGALTLYLKNPGMYKSVSAWAPIANPVNCPWGQKAFAGYLGEDREEWKRHDATELVKGWKGPLNALIDVGTADNFYKQQQLLPENFETAAKEAGLDGLTVRYQEGYDHSYFFISSFGEDHIKHAAKFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU67</accession>
    <name>A0ABR3YU67_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Golgi to ER traffic protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004803</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GET4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000145">
        <property type="protein sequence ID" value="KAL1891798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007317">
        <property type="entry name" value="GET4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12875">
        <property type="entry name" value="GOLGI TO ER TRAFFIC PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12875:SF0">
        <property type="entry name" value="GOLGI TO ER TRAFFIC PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04190">
        <property type="entry name" value="GET4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="338" mass="36823" checksum="E611F800F406C105" modified="2025-10-08" version="1">MSGCIDKIITRLEARIAEGQYYEAQQQARVVAARHIKAQNWEAAIDLLFRMTQALLKAGQGGSGGDLCLMMVDVFVQAKLKPDPNSRTKALGCLRLFDSEEPTRKKYIGEILGWSAKFGEFPAGDPELHHVVGSLYAEEHVVYEAERHLVLGTKESPEIFGRLEYTWYKESGSPHDAAVYASRAVLPYLLVANVRGAHTALNVFTTALSADNPALAVEHAEARGSNGGGFSVPIFPSLPLLNFLGLLLAVVQTGNAEMYKGLMAQYKNLVADAADMWDEALNGIAEMYFKIQRSKQHNPLMDMMGSLFGGAPTTGGAQKKMGIPLKDKIEAPVPEGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVL1</accession>
    <name>A0ABR3YVL1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000143">
        <property type="protein sequence ID" value="KAL1891912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034443">
        <property type="entry name" value="PB1A10.08"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42051">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED PROTEIN PB1A10.08"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42051:SF1">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED PROTEIN PB1A10.08"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="388"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="500" mass="54523" checksum="BE38B552CC6ED041" modified="2025-10-08" version="1">MAPHDGVRSVTQPILMKLPGRSTPTSATGPVQIPTKMQSDARNAKSVKRKSSSRSSRSMTSQTRSRPLDVHSPGAVPASVATLLAMTDIPKPRRHRSQRLSPEKDVLPLTVSSIMECVTDTELSFKLSKTSLDMLLLPPDEAHCELGSSMSIYDSDTGSTLGPRTDSLDSMPSLADSFVYGTPSSVGSSWGGCCKSERSVSRSRSRSNKQRPTRPSLEPISSPSGESEAHPLSKAVTIDELDFRMFGIGHDDSSSEAPKKPATTANSFPSMMRLAFKSNLTASLRAIRNAAKNISNINLSSIPPDDFLTRSIFAIDPKVPFTDERRPPVLEEEPSAALRRYLNPTSSARIEPRPAFDTMATMQNPLRPYTASIQMQTYKVYKSRNGSRSAASATTRHSSSFSAASSSPSSPTADDQAQTQTPSNQSSLSQPAGAMRQREMRENPDFIRVAVLEMAMRRNGKFDESHSGRARWTLPPRKPTRICEVTIDGIPERWVPKVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVP6</accession>
    <name>A0ABR3YVP6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">mRNA 3'-end-processing protein RNA14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RNA14</name>
        <name evidence="7" type="ORF">Cpir12675_004529</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 4">Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="4">Nucleus and/or cytoplasm.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000130">
        <property type="protein sequence ID" value="KAL1892446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045243">
        <property type="entry name" value="Rna14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008847">
        <property type="entry name" value="Suf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19980:SF0">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19980">
        <property type="entry name" value="RNA CLEAVAGE STIMULATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05843">
        <property type="entry name" value="Suf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Suppressor of forked" evidence="6">
        <location>
            <begin position="227"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="622"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="870"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="967"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="94"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="135"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="190"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="627"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="988"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1019"/>
            <end position="1028"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU369035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1892446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1028" mass="116356" checksum="900243232FB1CC5B" modified="2025-10-08" version="1">MSSDEKENAQQATAVDLAWKSPREMDVDGSDEYEPSEHQTEPPSIGGGDHESNDGEEDDDDYDPESIPIPENPSEMIVKSKSQTKTSGGFILEVSDDDENGDEEENNASSEQPKTANQPDHDEDLHEPEEPAEETQPNEIAQQELQTNKGSEPLVTPNVVDADHPVESVETAEDSQEPEESSPGPKEAGSPSQAKTASSQPQEHPAPIVPSMTFATGEPITIPTQSIAALEVRLKEDSRGDMDAWLSLIAQYRLLNNIDDLRKTYERFLEGFPQCTAGYVEWLEMELSLNNFSEAERIFNVCLVTITDVDLWTVYLNYIRRRNDLTNDTNGQARKVVAQAYDYVMDKVGLDKDSGKLWIDYIQFLRSGPGQLGGTTWQDQQKADQLRKAYQRAISVPTSVVNTMWKEYDQFEMGLNKMNGRKFIQEHSPSYMTAKGAYIALESLTRNLSRNSYPRLPPAAGFDGHTEFMEQVDLWNKWIEWEKSDPLVLEEEDNDAFKKRILHVYNQALMALRFCPKLWADCSDWCFANNILHVSTNTSMGMFILTQGRIANPESVLLALKHADRIESSPHSGDDDPNKAKFAAAVREPYNAVLDTLYEMCTSLKEKESSEITRLEQLEAAKEANGNQQPNPNFPQEPTREQKTQFIKDAYSTRIQLLNRTISFVWIALVRAMRRIQGKGGAHSGGLRQAFTDARTRGRLTSEVYVAVALLEAVVYKDPVGGKIFERGARLFPEDEVFMLEYLKYLHSKDDTTNARVVFETCVNRLTQKPETIYKARSLYQYFHNYESHYGELSQISKLEERMAELFPEDPKWTLFHTRFVSDRADKFDPLSAQIIVSPAIQQRPKIQHMMEMPPSSRETPAPGFRMEASPGPQYMRATNSPKRPYPNDEIEENRPRKFARGDSPLKGAAGRRLDQQRRVHGSTLHRDITFLLTLLPPAASFDAYKVNPSSLISLLTSTSVPDFHTWKSSQDPMAATRPVPAGPVSTHRYNTSQSGFSYGEYDGGSSRRGHQTGSYRQQADEQYRYQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW45</accession>
    <name>A0ABR3YW45_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000128">
        <property type="protein sequence ID" value="KAL1892561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046499571" evidence="1">
        <location>
            <begin position="21"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="104" mass="12009" checksum="175A1D21D7C904B7" modified="2025-10-08" version="1">MHLPIALSAVVSLFIAATSAHELTESHKKHMLRARPFIDHCQSHFSEESFKHRTAKRHLLNLNRARILEGLEDGSLDNPFDHHISVVQHSPLEVLHRTHRLFKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYE1</accession>
    <name>A0ABR3YYE1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal subunit assembly or modification protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SQT1</name>
        <name evidence="5" type="ORF">Cpir12675_004281</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000117">
        <property type="protein sequence ID" value="KAL1893090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051179">
        <property type="entry name" value="WD_repeat_multifunction"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857:SF8">
        <property type="entry name" value="ANGIO-ASSOCIATED MIGRATORY CELL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857">
        <property type="entry name" value="MITOCHONDRIAL DIVISION PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="131"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="231"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="78"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="10"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="479" mass="50700" checksum="8A1D6D09D85804FC" modified="2025-10-08" version="1">MSDNHRDNEEPMEDEFLHEDEAAEEFVPDDNDMEVESDDDNNQDNEEIILQNDSVAYFDQHRDSVFCLAQHPIHPSLIATGGSEGEDEDAPGKGYLIDTSAAPNRPVLPASFSSDPNSRPESVALKALFSIDGHSDSISALAFTLPKGQFLVSGGMDGHVRLYAVGVMPDQPVKFKWMAEAAEVSEVNWISPCPNPAHPHTFAVGASDGSVWVYTISPKDKATPLQVVNTYYLHTGSCTAGSWTPDGKLLASVADDSSLYVWDVFGEAAAHGITAENGMSVVSLNANDQRFAVGGGLYSLAVDPNGAFVAVGGAGGGIRIISLPRLGSTPSEVSPGGQILASLQTLNDTAEALSFSSPIVGAGQSQITLLAAGCVDGTIAVFDASRRFALRRTLPGAHEDFSVVKLDFVPGTWMVTSCGMDGVIRRWDLRAAADQCLVKEWKGHRGDGEGGGVLGFVQGESGERVISAGDDGVVLVFDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYF2</accession>
    <name>A0ABR3YYF2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Squalene monooxygenase</fullName>
            <ecNumber evidence="4 10">1.14.14.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ERG1_2</name>
        <name evidence="12" type="ORF">Cpir12675_004314</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 10">
            <text>squalene + reduced [NADPH--hemoprotein reductase] + O2 = (S)-2,3-epoxysqualene + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25282"/>
            <dbReference type="Rhea" id="RHEA-COMP:11964"/>
            <dbReference type="Rhea" id="RHEA-COMP:11965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15440"/>
            <dbReference type="ChEBI" id="CHEBI:15441"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="1.14.14.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endoplasmic reticulum membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Microsome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the squalene monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.14.17" evidence="4 10"/>
    <dbReference type="EMBL" id="JAWDJO010000119">
        <property type="protein sequence ID" value="KAL1892946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004506">
        <property type="term" value="F:squalene monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013698">
        <property type="entry name" value="Squalene_epoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040125">
        <property type="entry name" value="Squalene_monox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10835">
        <property type="entry name" value="SQUALENE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10835:SF0">
        <property type="entry name" value="SQUALENE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08491">
        <property type="entry name" value="SE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 10" id="KW-0274">FAD</keyword>
    <keyword evidence="5 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0492">Microsome</keyword>
    <keyword evidence="8 10 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="438"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="475"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="Squalene epoxidase" evidence="11">
        <location>
            <begin position="203"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1892946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="506" mass="55782" checksum="1EB40DA81318EE98" modified="2025-10-08" version="1">MPSSTDAKPQALSQVAGVPRAKYREADVVVVGAGVFGTAIAFAMANQGRSVLLLERWMRQPDRIVGELLQPGGCAALRKLGLGHCLEGIDAIPCYGFDVIYHGEECRLQYPSLNKATSQVVYKKDAHKYDPEELVQPEGRSFHHGRFINELRKSCLAHPKITVVETDVTKPVYSDHSDLIVGVEARTLSPATGQKEPDYFFGALTIIADGYASKFRKAHLGSTPIVRSRFYALELIDCPLPAPNCGHVIIGNASPVLLYQIGTHETRALIDVPEKLPEAMPNNGGVRNYIKNHVIPTLPAQVRPCMLEALSKEKVLRSMPNSWLPACKQRVNGMIMAGDALNMRHPLTGGGMTVAFNDAYIISQLLSPDKVPDLSDTAAVNNSMSEFYWSRKSLTGIINVLAQALYSLFSANNRLLRALQQGCFAYFKMGMTEGPMGLLGGLIHHPMTLFNHFFTVAFLSIWLNGWNMVVNNVAGFVLVPLAVMDLVFILWKASVVFLPVFYYELY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYF6</accession>
    <name>A0ABR3YYF6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004169</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000112">
        <property type="protein sequence ID" value="KAL1893386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="198" mass="21754" checksum="3371E698EE5A642D" modified="2025-10-08" version="1">MTTVFTPPCGAVIMAAQMETPECVAPGMSSVWRNGGFYSPGVCPSGYTTNCVRSEKRDGELIPVRPEETAAMCVPHHDVSTMTTPSTSVSMTLATVSLVQPIPTNDTRPPESSTTPATDEDPGEHNFNNSELSGIIFGICVAIMGLMMLIWCVMRYWEKNDCFSSGWSLRRNWNHRDSTRLYSPELVSTSPPMQQRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYJ4</accession>
    <name>A0ABR3YYJ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mmc1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000109">
        <property type="protein sequence ID" value="KAL1893438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056196">
        <property type="entry name" value="Mmc1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38644">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38644:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23868">
        <property type="entry name" value="Mmc1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23867">
        <property type="entry name" value="Mmc1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mmc1 C-terminal" evidence="1">
        <location>
            <begin position="310"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="556" mass="60394" checksum="7732E2FF8F5992B6" modified="2025-10-08" version="1">MHTDPRQELIRHLHEVGTHALGYASPTRLQLAINSLEQATGDETIRVAILGASNGESASSAKMLIKALFADPLADTQEWELELENHDPAQPLVVRISKFSDGQKSSLISQAGSLKELHIASPTWSKHNIEILFVEDRRLAGSHSYELSEDGLLDVPISIGGQTLVTPVHKVLSVADGITGASKLGAVSSLHKSPVTLAAVNIPGYSASCGEKLPFAVLNVGAGVDGLNLFRSSSSNGMEFERLWTQSNIAKVREWILEGAMSSPSETKAIIRNLVASTLDKTDAAILEAENGTKSTIGLETDPETASLVKALAEWSQSAHAELQDELDKAFSGQRWKQMKWWKLFWRVDDVGLLTSDILHSRFLPRSDKDMIFLAGRISESLPGHAAAYSQPMSVVLTDPKATDMASRLSGSTHNAHLTPRWPTHISFARRYLQEETVPALQALSQKLVLQTFSSAGLSASLGALIYVSQFSVYEAGSVVALGTVLGLGRMQRKWGNARKFWEDDVREEGRKAVRAAERSMADVLDGKAEESASSDKYTLLRDVVSRAKAALANLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYP0</accession>
    <name>A0ABR3YYP0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Vacuolar aminopeptidase 1</fullName>
            <ecNumber evidence="9">3.4.11.22</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">LAP4</name>
        <name evidence="9" type="ORF">Cpir12675_004303</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.22" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000118">
        <property type="protein sequence ID" value="KAL1893069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05658">
        <property type="entry name" value="M18_DAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.250.10">
        <property type="entry name" value="Aminopeptidase i, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001948">
        <property type="entry name" value="Peptidase_M18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023358">
        <property type="entry name" value="Peptidase_M18_dom2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570">
        <property type="entry name" value="ASPARTYL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570:SF4">
        <property type="entry name" value="VACUOLAR AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02127">
        <property type="entry name" value="Peptidase_M18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00932">
        <property type="entry name" value="AMINO1PTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101821">
        <property type="entry name" value="Aminopeptidase/glucanase lid domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="588" mass="63439" checksum="E6F69871F5B4A4C9" modified="2025-10-08" version="1">MVNNYRPALSPEVDMARLQQEFHNNESRMSTPWLQHRPSIHSMIAATEPSYAPLTSTSTAYTKQTAAQRAFVLGDLSHSKLDKNTVCHSCTSQLSPQQHVRVIPQMHGQECVLCAVQSGAPEAYTEPFCSFLTENPTIFHAVEYFKEKLGEAGFIELPMRDNWEGKVHPGGKYWTTRNGSALIAFAVGESYKPGNGVGMIAGHIDALTAKLKPVSSKPNRAGYIELGVAPYAGALNQTWWDRDLSIGGRVIVRDPSTGKTGIKLVKLGWPIARVPTLAPHFGVGMMGNNNAETQAVPIIGLDNSDLSAASPPAQPLGGPGSFASKQPPKLVKLISKELGISDYSLIVNWELELYDSQPAQTGGMDHEFIFGGRIDDKLCSWSALQGLIAGDHKPSDGYIKLVALFDDEEIGSLLRQGAKGNFLPLVIERSVEALAHEDEKTTFGPGIIGQTYSRSFLVSADVTHAANPNFLGSYLDDHMARLNVGVTICADSNGHMTTDAVSTSVLTRVGELAGCTTQTFMIRNDSRSGGTVGPTLSSMMGVKSADAGLPQLSMHSVRATTGSLDPGLGVKFFKGFLDLWEQIDGEWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ63</accession>
    <name>A0ABR3YZ63_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA polymerase kappa</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_003989</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000104">
        <property type="protein sequence ID" value="KAL1893691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03586">
        <property type="entry name" value="PolY_Pol_IV_kappa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.100">
        <property type="entry name" value="DNA polymerase, Y-family, little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036775">
        <property type="entry name" value="DNA_pol_Y-fam_lit_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017961">
        <property type="entry name" value="DNA_pol_Y-fam_little_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050116">
        <property type="entry name" value="DNA_polymerase-Y"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022880">
        <property type="entry name" value="DNApol_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002677">
        <property type="entry name" value="PRK02406.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11076:SF33">
        <property type="entry name" value="DNA POLYMERASE KAPPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11076">
        <property type="entry name" value="DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11799">
        <property type="entry name" value="IMS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100879">
        <property type="entry name" value="Lesion bypass DNA polymerase (Y-family), little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UmuC" evidence="5">
        <location>
            <begin position="125"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="589"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="605"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="620"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1893691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="630" mass="70267" checksum="A56946972D2088AD" modified="2025-10-08" version="1">MAPVTTNHLQFENLEHANSDDTGPDAAQDRDVEHKSLKYHLLGQSATKAGLAPDQSKISEIIYEASKGSKFFQREEQKDKILSEKIEKLKAKAKGLPEGVLFKAARDADLLLAELEATRDLSQHIVHVDCDAFFAAVEELDRPELKDVPFAVGQGVLTTANYHARKFGCRSGMASFVAKKLCPHLILLPINHAKYKAKAEEVRNVLVDYDPRFESASIDEAYVNITAYCTEHQLTPEAAVDKMRSEVHIKTQITVSAGIAPNARIAKICSNVNKPNGQFCVVNQRDAIMSFIGALPTRKVNGIGRVLERELAGALNIHTCADLYTQRQFLALLFGDKAFHFLARVYLGLGRTNVQPAEEYKRKSVGTESTFGELSGAEALQNKLRVISEALEKDLAKHEVKGRTLVLKVKLHTFEILTRQAISPRPLASAEDLFTCALPILAKLQAENNKMTLRLMGLRCTNLLSTKKADPLAFFGVQNRPVENNGISTPRPSLPLSTEEEWEEWPAEELFPAEQDTEFAVPQDDGNMAKAEARISHTGSATTKTRQEEPAERDLWDCPICLHPQQPEERSFNEHIDLCLSRQTIRDAVEESSSVGTYPETVVQVRRRGSNKKRGRSHRTKDPKQKKLCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZJ8</accession>
    <name>A0ABR3YZJ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_004167</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000112">
        <property type="protein sequence ID" value="KAL1893384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037652">
        <property type="entry name" value="Mim2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28230">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28230:SF1">
        <property type="entry name" value="MITOCHONDRIAL IMPORT PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19117">
        <property type="entry name" value="Mim2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1893384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="105" mass="12268" checksum="4BEB7AD33E759EBA" modified="2025-10-08" version="1">MSVHSSFVLPDDLFSEKDELDSLPESDDTSILDIEAEEAAQEEWERNLEQMQMLLGCVIVPWIGKFLGRKFAIYSWSRYMEWLHNVEIQWGTKRQSKTSKASIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZN6</accession>
    <name>A0ABR3YZN6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Isovaleryl-CoA dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_004128</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000110">
        <property type="protein sequence ID" value="KAL1893429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884:SF18">
        <property type="entry name" value="ISOVALERYL-COENZYME A DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016578">
        <property type="entry name" value="HsaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="8">
        <location>
            <begin position="51"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="7">
        <location>
            <begin position="165"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="6">
        <location>
            <begin position="273"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1893429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="431" mass="46241" checksum="5227D4083A221B8B" modified="2025-10-08" version="1">MSLRTLRPTHMAFLSHIRTRTASKLPSLSASIRNHSSKHPEGFTPPTAADLSELRDRVQDFTRREIPPSLAATTDQTNAFPSDLWRKLGSAGLLGITAPESLGGLSMGYQAHCIVMEELSRASGSIALSYAAHSQLCINQIALNGTAAQQEKFLPGLIGGTHVGALAMSESGAGSDVVSMRMTARAIDGGFLLNGTKMWITNGPDADVIVVYAKTDPPAGPKGITSFLVDTSQASGFKCLRKLDKMGMRGSNTGELAFDDVFVSTENILGAVNGGVRVLMEGLDLERLVLSAGPLGLMQAAMDVVLPFTHQRKQFGQPIAKNQLVQGKLADMYTKMQAAKAYTYATAKTVDQEGLIRTQDCAGAILYASERATECALDCIQLLGGMGYTEEMPASRIFRDAKLYEIGAGTSEVRRMVIGRAFNKEYSHLSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0E9</accession>
    <name>A0ABR3Z0E9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_004035</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000106">
        <property type="protein sequence ID" value="KAL1893647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056552">
        <property type="entry name" value="Ribonucl_Kappa"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23489">
        <property type="entry name" value="V-ATPase_su_f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1893647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="92" mass="9879" checksum="1828A47BFB2BA699" modified="2025-10-08" version="1">MAPKPAQSVGRNFAPTTVISAFAILILTVIGFLFKSGHEELTGGIEDPAPEMGPEIAGTIFTAVWVYIGFFIFCGIQGMLHVRENRRGAIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0N0</accession>
    <name>A0ABR3Z0N0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2293 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003887</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000100">
        <property type="protein sequence ID" value="KAL1893870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018744">
        <property type="entry name" value="DUF2293"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38113">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38113:SF1">
        <property type="entry name" value="DUF2293 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10056">
        <property type="entry name" value="DUF2293"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2293" evidence="2">
        <location>
            <begin position="184"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="491"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="574"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="657"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="728"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="781"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="848"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="892"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="521"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="574"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="700"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="733"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="853"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="896"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="908"/>
            <end position="921"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="933" mass="104358" checksum="BFBB981DAE8EFF08" modified="2025-10-08" version="1">MVGKGKHKDGGPSKRKATGSGKPHSHNKSRRYQQNHRSGAGGGGSDRADIVTQNLVAKKAVPQLKHQSYIEIVDNVDKKQKKLELEVTFNTTPPAGFEFVPIGNPELTALCKDISREKTAMIFVVSNSKAHQNELSVHMNRMGHHVRQTIVEEARKKLGYKGTSTVTDALPETQELINAQADAALRDLFPRIPNTDRQEIINYAFRLGAKFHGEPVVGLQTNLTLSRRAQLAVLSHIRHNHTRYDELLRETTWMHARKAVENPCLDVLVQWRGDEENGRDSLDEILREVVIISDDEDDEDLSTDDDDDDDNSDDYASDTMDTGENSKDSHINVDVVTAPLAKPMPQPASRISHHFALSSAGSSQNHPILLSSPASANYHGQHIPGSPHEVTSASRSHHSDRITRYRYANARLRDAWNSALGRHRNGVGASHDVPVREVLYRVGPPPQPTITSASSEDHIPMPVSVPIHAAAVASSTVHVSSLPHGTVSSAAERVAASPVNVDGTRTAPNTTSGPSTAALPQGTQGQDVGVFSQSTDQRKLGSPLPVVQSRPRPATQTNSATLMQEFAVPSIETSPAQPLATSNKTSHGHSVNSNGKRSYDDNSDNCPRYHGSGSTAFPTRPWNDSPYHKRRRATGYSPFGSYNSRQSEYNRYSIWDSESRPRSRLVDNPSPSNFRRPLRPPPHGYDQHHHSSNTLASRPPRLEEHGSRQHPIDVDDRLYVQPYRPHDYKAQQEPEQQQAQQQQQPSNAAPAVARPPPYHATGNETIRNVGVAYYQDEFQRPVAPQPGMHDNGEWSNPHTPHIPPDTSGSSTLHLPYQHYEKNYQNWYAYPGPTDSHVLLPLQHSYEFPHQPRRREDPGFNRDREREIERERELENERERSRLRLLEPESEMTYEKCRRRLSRRYKTLPPTSRRATSPNPSTFYVRPSHTARGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1G1</accession>
    <name>A0ABR3Z1G1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Arp2/3 complex 34 kDa subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ARC35</name>
        <name evidence="8" type="ORF">Cpir12675_003689</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the Arp2/3 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
            <location evidence="1 6">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ARPC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000091">
        <property type="protein sequence ID" value="KAL1894460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1460.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007188">
        <property type="entry name" value="ARPC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034666">
        <property type="entry name" value="ARPC2/4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12058:SF0">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12058">
        <property type="entry name" value="ARP2/3 COMPLEX 34 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04045">
        <property type="entry name" value="P34-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69645">
        <property type="entry name" value="Arp2/3 complex subunits"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="298"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1894460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="318" mass="36854" checksum="FB229AFFD83649ED" modified="2025-10-08" version="1">MLLLDYQNVLIQNVLTERFSGAAPTHIDQTVSDFDGVIFHISTPETKTKILLSIQIRCFKDLLKYGADQVLQREYNNYVAPTEPGFDFSVQVDLEDLPSDKEARDALVMKFALLKRNAMAAPFEAAYQEHYKLRDEASKYTTEEAPQGLREGSEVMAIHYREEESIFVKASHDRVTVIFSTIFREETDKVYGKVFIQEFVDARRRAIQNAPQVLFRNEPPLELQGVPNINNPNNGEVGYVTFVLFPRHLTPQRMDEVVSHIQTFRDYFHYHIKASKAYIHSRMRKRTADFLQVLRRARPDSEEKERKTATGRTFKVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3E8</accession>
    <name>A0ABR3Z3E8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003344</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000077">
        <property type="protein sequence ID" value="KAL1895161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="201" mass="21121" checksum="4F39175F32574CCA" modified="2025-10-08" version="1">MAIYIPESTSAAGAAISAAVVSNAAALRTSLLRTSFNLRKTPATNNSASGSSKQSKYAEKVRAAETEDLRNLPQHNSGIGCKPDDKALQAKRADEDLRRKLQLGRKRGADVAVLGAESSDEEEGRSALGRSKRAKKTNGKENKIPELEAKTGEVISTDIGGVILVASAAGLEPKPAGVVETSGRSKKNKKKKKNKAVLEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3N4</accession>
    <name>A0ABR3Z3N4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphatidate phosphatase APP1 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003372</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000078">
        <property type="protein sequence ID" value="KAL1895143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017210">
        <property type="entry name" value="APP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019236">
        <property type="entry name" value="APP1_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052935">
        <property type="entry name" value="Mg2+_PAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28208">
        <property type="entry name" value="PHOSPHATIDATE PHOSPHATASE APP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28208:SF3">
        <property type="entry name" value="PHOSPHATIDATE PHOSPHATASE APP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09949">
        <property type="entry name" value="APP1_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037464">
        <property type="entry name" value="UCP037464_APP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphatidate phosphatase APP1 catalytic" evidence="2">
        <location>
            <begin position="321"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="482"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="556"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="624"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="525"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="561"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="639"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="812" mass="88816" checksum="D3FF0393FAC89231" modified="2025-10-08" version="1">MSWTSFATGSSSDLNGSTQRSSRRQKLAAMAGNVYRAGATAVDGIRETYAQSRGAWAYDVTNMEPMSTVFPECGIVSQGDDSILIFPTYAKPHSRPKIPRRYTAEGDELSDSGVRDDEAWIAEWERTADKNAVCDVDVRGWLYSPQRPPLTKRMRLMVALARSMSGIPVTRQDQSLTPDEAAMEAEAMAEIDRFGAGPMASKSSNTTSLGPSLARRTTASTTGSSSIEMTAEEIELANDILMKRISPFLTSPIYQMPVSVFFYDSNNSQSQTLYTDDSGHFRGRVALRFVPTNMRILANVDMNNSGLSKTIQVKMTQAHGISVISDIDDTIKYSNVTGGPREILRNTFVRDLNTLSIDGVSQWYNAMAAMGVSFHYCSNSPWQVWPLLATFFHISSFPHGSMHLKQYNGMLQGMWESAADRKRPSLERLLLDFPQRRFLLIGDSGEADLELYTDLALQYPENIIGIFIRDVTTPEPQKVPVSCISQSANGPKEQAKLVSPPPPRLGATSDTSLKKEILPPPISASVKSTASQVSTPPPPQLPIRLNWDQREFNPALKKHSSQASLNAQRTLDSPHPGLPKKTQIKPRPPRPVKPVNLQAKVADTLTGSPNATSLLGSAPTTLLPVAQNKSPSAGHRTVSHTPYKSNSEIDLRSCVPNGQKKNGLPRDLAQLPPPPPPRRRIAQSILPPPAPAASMGTAAESRSKSNIAASMASAINTATKTSNAVHEKPMSHHHHHPHLTPALAPVAAMSSAAAVSPEAQTPAAVQRKIEIWQARLKDAHWKLDGIRIPLYTWRDGHEVEETAMKIIKSYNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z424</accession>
    <name>A0ABR3Z424_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_003448</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000081">
        <property type="protein sequence ID" value="KAL1894989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01389">
        <property type="entry name" value="HMG-box_ROX1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050917">
        <property type="entry name" value="SOX_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45803">
        <property type="entry name" value="SOX100B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45803:SF5">
        <property type="entry name" value="SOX100B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HMG box" evidence="8">
        <location>
            <begin position="156"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="6">
        <location>
            <begin position="156"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="96"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="449" mass="48591" checksum="0561E9D1309D6FA1" modified="2025-10-08" version="1">MPFAQPTSSKSTSAGSLGRAPRVCPSMMNFPPPSAASRTRNKDASMSEPTIARPNLRNRSQKAKLGSARKSGNAGKHGSSGDSVPIMAGRIEKIPSPKKRGDKVRPGRRSAAIRSPLSQLARQFSSIEIPDIDSFVKRSFEERHAEINLGKNPGKVKRPMNAFMLYRKAHQMLAKTICCQKNHQYVSQICGDSWAIEPMAVREKFNVWAKMERINHQTAHPEYKFSPNKIEEKVPAGGDETEVEDADAEDDLSITFDAVRLGSPHSSHLGQGDFDMHKASYGVPPSEFQVISAVAGAVPTQSTSSSFGSGPVSSLASAPSPTLAAHAESPLFTTSTESQLANTSPQAATGTQQIEPNMTVVNGTYFPPFPNPENFFDADAYPNPVAMEFGVPFFGFEEEANTMLETFEIEPNAHQAVDDVPVDQGPINPGENWVYFPPTPSLFGTVAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z473</accession>
    <name>A0ABR3Z473_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003485</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000083">
        <property type="protein sequence ID" value="KAL1894840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012:SF7">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="2">
        <location>
            <begin position="72"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="565"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="212"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="247"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="379"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="574"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="694" mass="77122" checksum="D9FC99621D4EE97B" modified="2025-10-08" version="1">MYDSSNSDGPSAVTTPGSQPSQTQTQNSRALAPRPSDGSSGVDSDLAHPGAAGTLSGSKKRVVQASRGVATMTPDRLARKRANDREAQRAVRERTKAQIRELQDEVSVLKNDQAHLQHILQENSALQAENTAMKQAMAQLVHQLDSQNIGQQSSMQHHQHHHEHHHHHHNHRGSHYRHRDQRISQEYSRSTTKSSTVTGESSDQSFHRDNSGESSSSSDPNCCSPGNSNLVLPSIEEMTRRPFPDASKGPGSSYSHDSSSKHESNMTHQRESFEQNSFKDHQPSFQPMDKHHHHRHQHRHQNQHQKPQQYGYSSSPSLSPPYYQALNQETSRFMLSTHINLEDLPNMSASVGDFGKPNVAMIEALENFYGNGNGRHADGNGNDSWNGNGKKYNNDGLNDTNMGNSENGSIDNRTVRKGNSLYNNSRHIKLPLLHASSTCEIDSFLLPLLSMSDQCQPTQIDIAVLLAPSIVSYNPQRVKLDPFSTALAEIMLLVEPPADERVPERVAVMYTAFLLIRYMMNATTENFGCVPEFLKPLEDQLERTHAVWIDFIPFPHARIKLIADSSREGGDNDGGNSNSNDGGNSNSNDDGVSIDSSNGNGDEGRTTSDDSSTARGAEPPRPFFLEYFACLSINWPYQDSDVLLAANGSDAGSRELMINPVFEAHIRKLENWSVSRDFLDTFPEFEHLINLQEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z572</accession>
    <name>A0ABR3Z572_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peroxisomal-coenzyme A synthetase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_003539</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000086">
        <property type="protein sequence ID" value="KAL1894649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05926">
        <property type="entry name" value="FACL_fum10p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045310">
        <property type="entry name" value="Pcs60-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF5">
        <property type="entry name" value="MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="5">
        <location>
            <begin position="27"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="6">
        <location>
            <begin position="423"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1894649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="516" mass="55941" checksum="20671E24F5DECA8D" modified="2025-10-08" version="1">MASPLTLQTAIQGVTSSVAVIVPSKPTPVTATYAQLVADITDFRQKLAEIGIGKGSYVSLALINSYEFIIAFEASAWQSAIAAPLNPNYKQAEFEFYIDDVKSDLVLVPRGAFNASSPAVKAAQKFNAAIAECYWDAQESRAVLDIKDSGKLKGKKSRVLTAAPDDVALVLHTSGTTSRPKVVPLTHRNLTRTMMNIKNTYQLTAADRTMLVMPLFHVHGLLCGLMAPLYSGGSMVVPTKFSASDFWADFIAHGANWYTAVPTIHQIILKNPVPSPLPKIRFIRSCSSPLSPTVFAQLEKTLQAPVLEAYAMTEAAHQMTSNPLPPAKRKPGSVGLGQGVQVKILNDDGDEVSQGNEGEICIKGENVTSGYLNNAAANATAFAKNGFFRTGDQGKMDEDGYVIITGRIKELINKGGEKISPIELDNVLTCHAAVSEAVSFAIPDEMYGQEIGVAIVLKQGQSLKPEEIKAWVSERLVKFKTPKEIYFTNIMPKTATGKIQRRIVAEEMLKQVKPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z599</accession>
    <name>A0ABR3Z599_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">VASt domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_003248</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YSP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000073">
        <property type="protein sequence ID" value="KAL1895387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13220">
        <property type="entry name" value="PH-GRAM_GRAMDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051482">
        <property type="entry name" value="Cholesterol_transport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004182">
        <property type="entry name" value="GRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031968">
        <property type="entry name" value="VASt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23319">
        <property type="entry name" value="GRAM DOMAIN CONTAINING 1B, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23319:SF4">
        <property type="entry name" value="GRAM DOMAIN CONTAINING 1B, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02893">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16016">
        <property type="entry name" value="VASt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00568">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51778">
        <property type="entry name" value="VAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="VASt" evidence="7">
        <location>
            <begin position="835"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="111"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="229"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="406"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="468"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="731"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1007"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1144"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="26"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="136"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="158"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="172"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="194"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="279"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="356"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="406"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="468"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="490"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="519"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="750"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="766"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1025"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1161"/>
            <end position="1175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1214" mass="130549" checksum="9A22DDB336C513D8" modified="2025-10-08" version="1">MGASRQETELISPPSSSPIPPTSLSASRSPRLRQTSPSLSTPPKEDTRAGRFPVRVSRGRLRNSFSSEEKQKRFSTPLSPPTTQTVSLQDTDLDISVNSASNYTFSAYSTLRNQPSTSSLLSIARSRPESRDGSQPDPSYQISSHKSSTFPRIRRSDTGANGSSTRLALTKSPGSRRSPSPGGKLRGIFRVKRSNSSLVSSTSEPGDILPESHGLSKVPAASSLALVQEDDSLYTTQDSSQRSLPTPINSQSSVTPPKTPPTGTKAPVFEIINTPPTPTKSQIPSSKSSIKSIFSSPSSTFLEPPSLDGPVVQPPPPPPIIRVSTSGILPGQRRLRSGSTGPSKLSKISRPPLSPTPESASNTPSNDTPESVPDIPVLSPGFLSSMLSAAQSAATSIGNSIVNTASTTRGTKTRSLSLSTSNSVSEAASASTPQLELAPSPTIPTAMERKEPAVKTLGAGDLSLSQLGFNDPASTANASSINPSQMPNDISHEPLRGRSESSPADPQHPAEMGADEHSQSMYEKSTSDASPNHSVYGDANVATAAGIHRSGSIRSALERHRKRGGSAATGNTIGAAIAAVNHPSLPLHTPYSTSVPKLTGFAIASKKRNKDFHTLFKSVPDDDYLIEDYSCALQREILCQGRLYVSEGHLCFSSNILGWITTLVIRFDEIVAVEKRNTALIFKNGLMISTLQNRHIFASFTSRDATYDLIINIWKLGHHTLEITADKTEKTMDDPTVPLQHDDVHSGSEDGSDEEDDVYDEDDDNTYSTPESVTMANSSFPEADTEKTGTRKLSTTGGTGGTASDVPPASAGSGQDFPGPATHGPTDCGDEANHYDRVVGDDIMPAPLGKVYDLLFGPASVNFLQKFIIENQRCTEYTTEDRKGLTSDNKTRTFTYIKPLNAPIGPKQTKCIVTEMLDVIDLSKAVNVTVSTQTPDVPSGNVFTVKTHYCLSWAENNQTRIQVNCTVEWSGKSWIKSPIEKGANDGQVQYCNDLFGAIRLAISTRPRAGTNSGAATKSKKKSRKSNAAESSPIVPAVAPAPPPTNWGPLEPARFLLEPVVEIAKPFLAGNLVYGLLAGLLIATWLGFGSQPTTHSTGVYNSGAHTHMGFSTYPDRIVAYEEMWRREESQLWDWLEERVQLGRMMGDPSATSSGTPPGMRRKPTESRTVEDRLREEKMDELQIKEAIAVTQRKLDLLKEAMEKRVAAKERMGEGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5B5</accession>
    <name>A0ABR3Z5B5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">rRNA-processing protein las1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">LAS1</name>
        <name evidence="1" type="ORF">Cpir12675_003209</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000072">
        <property type="protein sequence ID" value="KAL1895520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007174">
        <property type="entry name" value="Las1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15002">
        <property type="entry name" value="RIBOSOMAL BIOGENESIS PROTEIN LAS1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15002:SF0">
        <property type="entry name" value="RIBOSOMAL BIOGENESIS PROTEIN LAS1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04031">
        <property type="entry name" value="Las1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1895520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="336" mass="37455" checksum="7E13F8143DB6CBE7" modified="2025-10-08" version="1">MVQYVFTPWRDAVELEQVKRAFYPEASLGTGFGGPASAQGTSCTQQQQRHEAVDRVAMWMQRGNCPHMIESTALLTAAIIADEEQQQLARGPGVGLSEYAMRAAYSTSFSRFVTGLLDGQQDKLRKMSMFSLAKNIGLPATFVELRHQATHEPLPSLSRLRAAARKALVWIWEYYWMHLPPVDIEEATTTVSGPETWSPQGNHMVQKALSTGAQKEVLCFLESREAMEPEAREQMAAAWVQKWGVQAVTRVVNAVNETATQRQVMLRAIQMSRAIEQLEDEVAEEDGQGDERQGVVLEREQMGHDMPQDLGDEDGEDGCGWTVYAGKWRAKPIGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5J1</accession>
    <name>A0ABR3Z5J1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Partial AB-hydrolase lipase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003206</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000072">
        <property type="protein sequence ID" value="KAL1895517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006693">
        <property type="entry name" value="AB_hydrolase_lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11005">
        <property type="entry name" value="LYSOSOMAL ACID LIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04083">
        <property type="entry name" value="Abhydro_lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Partial AB-hydrolase lipase" evidence="3">
        <location>
            <begin position="247"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1895517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="639" mass="70393" checksum="6B48F795A9FC2E75" modified="2025-10-08" version="1">MATTITTAATITTTAASVLRSIPAIESPISDEPPISPSQTQIQACTQSQSQSHASNKITETPSAPASIGAPAKQEPSVTPLHPPAKAARSAFQRARKPSIELQNLPPRRPLPALVPVVGTTLAPNAGSSTEPTGSHSAANAFPPLGLGTRMKERILQLSSFTLSLAFLSTIAGMALLRQIPPIMMDWYHHLNKGNYNESRRPFYATEKKLHAKRRNDVDQWARGLHGPLTDGFVPSEGGTDKLVCDVRYYARRVGLDTETVLVQTDDGFILELWHVFNPCHYKGMTATSGNRSGNATSPKRGEKYPVLLVHGLLQSSGTFCVNDDRSLAFSLAKTGYDVWLGNNRCGFHPRHVALDPSDSRMWAWDIREMATLDLPALVSGVLHHSGYSTLGLVCHSQGTAQALLALSRDYVPELSHQISVVCALAPAAYAGPLVRKPWFRFMSLLPQPLWRVVFGVHSFVPAMMLAHRWMPAVPYGSFGYIVFSFLFGWSDARWERDLRARMFQFAPVHVSSALMWWWLGRDGFAHAGSIIKHAAEDPQSPHTPEQYEADAWYPAGTPPLALWICGNDGLVDGEKLLARLNSPREPYAKVVHAKIIPDYEHLDVLWALDAPEQVNEEVARVLWDTCPVQEMCMRPIGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5T3</accession>
    <name>A0ABR3Z5T3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mitotic fidelity of chromosome transmission-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MIF2</name>
        <name evidence="8" type="ORF">Cpir12675_003351</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CENP-C/MIF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000077">
        <property type="protein sequence ID" value="KAL1895168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06993">
        <property type="entry name" value="cupin_CENP-C_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028386">
        <property type="entry name" value="CENP-C/Mif2/cnp3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025974">
        <property type="entry name" value="Mif2/CENP-C_cupin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028929">
        <property type="entry name" value="Mif2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16684">
        <property type="entry name" value="CENTROMERE PROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16684:SF11">
        <property type="entry name" value="CENTROMERE PROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11699">
        <property type="entry name" value="CENP-C_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15624">
        <property type="entry name" value="Mif2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mif2 N-terminal" evidence="7">
        <location>
            <begin position="15"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Mif2/CENP-C cupin" evidence="6">
        <location>
            <begin position="577"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="75"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="136"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="258"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="282"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="299"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="317"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="336"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="361"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="376"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="418"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF15624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="683" mass="74375" checksum="1991A0BA754BF9FE" modified="2025-10-08" version="1">MSQARGAARRQTQQIYELGQAGRKTGVILPDNGQRDENGLQPLDGLFSSPTKPDGSTPRAVERSIMGEQDMEIDQASSPGPSTIMRNRRSGASALPISRSPVRTSLGSPALKNPHLTSRPSPARPASRLRGYGDSATTTAPTVTASAANKDNPQTISRNLFAVPKAQHRPRPNGTSRSRRFFPESDEDEDDDDVLQPPAQGDIFDESMQMIEEFIPQSDAPQLPDDEEGQQEPTPRPTKRFNRSSGETPNKLEPLKPSSKSTATAANNRGPLKRLRQSEPEPQSESDENTEEQEEEESMSSPSIQAPVDLPPPNPPRRQASRSSQSVPPTKPPPTTASKPTSSASATKARVKPSPAQTLNRKARVSGRSKKTAMPKSSAATGSNASNNDDNDNDAGDKSLLEVQRGPPPPKRRGLMSVRTNDNITTTRSGRTSYAPLQFWKGERAEIATETFRDTNSKQAFVLAATKEIIRVEDDDPPASKRRRAARPAGRRAASAAAANISAKRVASGSGAGELLLNEPLEEWERDPGVVDGDVVLWTYEHEINPPGPDEEVGIITEQLAISGGAVETREIKDATFRYAKTMSLGFMGSGIVDLPPGSEKRPKNSRRMQLVFFVASGKVKVTIHDNEFRIGAGGQFFVPRGNYYSIVNDYDSPARIFFAQACEMEMQQYEEGEEAEEMPEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5T5</accession>
    <name>A0ABR3Z5T5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Heat shock protein ssb1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SSB1</name>
        <name evidence="4" type="ORF">Cpir12675_003155</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000070">
        <property type="protein sequence ID" value="KAL1895572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1895572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="614" mass="66736" checksum="43BB93B8A0CD3D19" modified="2025-10-08" version="1">MADEVYDGAIGIDLGTTYSCVAIYEGTNVEIIANEQGNFTTPSFVSFTDKERLIGEAAKNQAAMNPTNTVFDVKRLIGRRFDDPTVKKDAETWPFKIVDDAGSPKVEVEYLGETKSFSPQEVSSMVLLKMKEIAEAKLGKKVEKAVITVPAYFNDNQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLGAGKSEKERNVLIYDLGGGTFDVSLLNIQGGVFTVKATAGDTHLGGQDFDTNLLEYCKKDFTRKTKKDMSSDARALRRLRTACERAKRTLSSGAQTTIEIDSLFDGEDFTVQITRARFEELNSKAFAGTLEPVASVLKDASIEKKGVDEIVLVGGSTRIPKIQKLLSEFFNGKKLEKSINPDEAVAYGAAVQAGILSGKATSAETADLLLLDVVPLSLGVAMEGNIFAPVVPRGNTVPTIKKRTFTTVADNQQTVQFPVYQGERVNCEDNTSLGEFTLAPIPPMRAGEAVLEVVFEVDVNGILKVTATEKTSGRSANITISNSVGKLSSGEIENMINEAEKFKTNDEAFSKRFEAKQRLENYVGHVEEIVSDPTLSLKLKRGQKDKIESQISEAMSALEIEDSTAEDLKKQELALKRLVTKAMSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5V7</accession>
    <name>A0ABR3Z5V7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histone deacetylation protein Rxt3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000064">
        <property type="protein sequence ID" value="KAL1896004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.20">
        <property type="entry name" value="LCCL-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036609">
        <property type="entry name" value="LCCL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013951">
        <property type="entry name" value="Rxt3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08642">
        <property type="entry name" value="Rxt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69848">
        <property type="entry name" value="LCCL domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="748"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="801"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1095"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="315"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="466"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="505"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="588"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="626"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="639"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="652"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="688"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="698"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="752"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="854"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="900"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1097"/>
            <end position="1107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1263" mass="136264" checksum="7ABBE4DDF6EA45F4" modified="2025-10-08" version="1">MDSLQSQSQSQLSQPSQPSLSHSQPPQSSQPRHPSQSVHSRGSKPSPSAASSQQQEKLQQPQKQPHSLLETPHSQQQQQPKQSLQSQPLNQPHLQPQPHQHLQQSPSPSPSLSHPHSHSQSLSGSYTRSSFAQSTAAAAPQSAPSQYQSQPPAPSHSHSNRSPNGTDQPARSASSNFYSTSTGVRSYAPDQPALPPAPPLNSAHARHHSSSLPAGSSVLPLSRNMPPPPPSSYMVGRDLPALGQRTTPAGSSMSISAMLGGASAAGRDSKQSASSGHLPPAHYGSVPGPSSQGSAYPPSVHASPIMQHRSGPPAQQQSQQSQQQQSEYHPQYRRPHTPDQSRSYDANRSTHASPRSAAYTPDVKRYSNGKSHSYHQRGIPPAADSRDPGRMSMPQLPTQAPLLPPSRPSSQPKEFPKSRPGDEPRRVPEEAYGNRHEEMGASGRPPITPDYSSERAPQMKPGVGAYDDRYRYDRDRSQPEHNPRNRAPVARERTLSTSDGRHPAHGGPSSHMGHPSHVGSSHSVTPQGGSGPGPEYAEYGSARNISPSHYVRGPEAGHWQQRPHYDSSRPSYDQHGARRSLEYPSAMGSQYGHPQGHPQQQPQGAPQSYQQSPHPDRFQNHAHAQPNDQSPQGSSMHTNFDRSPERPHANAVHSQSHLSTGSQQQPHTQLGCYTRPTEDGPPPPPPAVSNAAGPGNPTHNNDGQPMRITSASFDSSSRHKPSGKILTAPPLQRSNSLLAIQEANRNKGRCSPLPQAVQGAQPQAPGPTGEPVIKSEFGRMFSGIGMSLNVGLLSPAPVVPTPTSLGSGGPESQHLTESETKTKGRKKKLRDETSAEEDLAAKLLSGTKAIPGAKAKRLKTHAHTHTHAHAHTHAHSHPHHHHHHHHHHHHHGSDGASLGPRKDDANSPIDGHRLAAPHHHHVVSRSDGSDQNRVLGLVTAASTTDVSQLAPSPVVAIPPQKKMTVTSQLVLDSVAHKSRHFLGDVVYDPIITAERLVPIHSSNRGYKTTPRSLPLHLIKDKENCTLTVKIPKVHLHPAAREEITTRRAVWGTDVYTDDSDIIAACIHAGWIRGEWPEDVDTDLLDLHRGIGYDEKLGSSNANTSSNKPTDKDAFENDRQASHTAMHLTAPPATGPVPIRPGCDLQVTLLVLPKLRRYASSTRFGIQSREFGRNHDGLSFMITGMRWVVNGAAPQSRLRGKARRERMRQALAAVRFPQPPGQGQIQSAGVESAKQAVAASVARQAPGELMDGVQRTGNLTAITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6N9</accession>
    <name>A0ABR3Z6N9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Class II aldolase/adducin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000065">
        <property type="protein sequence ID" value="KAL1895985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051017">
        <property type="entry name" value="Aldolase-II_Adducin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004855">
        <property type="entry name" value="PRK06208.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672">
        <property type="entry name" value="ADDUCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672:SF25">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 14 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="AraD/HMP-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Class II aldolase/adducin N-terminal" evidence="1">
        <location>
            <begin position="66"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="303" mass="33203" checksum="73FEF24892C37E5F" modified="2025-10-08" version="1">MVASSTGTLTATATTPTSAIACTATTVATTKPNVNENFARIATGGIPLPGIPAFTDPYQKRQWQLEHMAGAFRVFARKGFVEGAAGHISVRDPVNPSTFWINPMGVHFGMLTARDMVHVDENGTVIGGNRRAVNAAGFMIHSAIHRARPDVHAACHAHSAQGKAWSAFGRELEMLNQDACIFWNNHTVYKNFGGVVLAAEEGERIAEALGPKHRSVILQNHGLLTVGSTVDEAAYLFTLLDRTCEVQMIVESTRLEKKIIDDKEAQYTYVVDADPETLYSEFQPDFEYEIWKSNGELTKDPQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7C7</accession>
    <name>A0ABR3Z7C7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DnaJ homologue subfamily C member 28 conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002971</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000064">
        <property type="protein sequence ID" value="KAL1895995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018961">
        <property type="entry name" value="DnaJ_homolog_subfam-C_membr-28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39394:SF1">
        <property type="entry name" value="DNAJ HOMOLOGUE SUBFAMILY C MEMBER 28 CONSERVED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39394">
        <property type="entry name" value="YALI0E31793P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09350">
        <property type="entry name" value="DJC28_CD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DnaJ homologue subfamily C member 28 conserved" evidence="2">
        <location>
            <begin position="1759"/>
            <end position="1829"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="446"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="975"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1099"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1300"/>
            <end position="1324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1341"/>
            <end position="1360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1381"/>
            <end position="1419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1480"/>
            <end position="1554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1598"/>
            <end position="1636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1711"/>
            <end position="1731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="114"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="210"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="463"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="482"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="977"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="999"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1113"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1396"/>
            <end position="1418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1486"/>
            <end position="1498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1517"/>
            <end position="1530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1598"/>
            <end position="1617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1715"/>
            <end position="1724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="2050" mass="218000" checksum="F476FB759D75ABD3" modified="2025-10-08" version="1">MLSHLRFHRRGVSNPTSPTLPTAPVPDGQPPSQRVHGLNIAHGHGHGHGQAQTQAQAQAQAQARSQPESRSQGNSPYLQSHAQFQPLPQSQTHSQSQSQSASRTSSPHRSKTKSLFLSPSSLSSGSAFDTAPFTLPSIPQDVASDIPSAISPRQSASAVSSPIPDDNSPSTRFIGGLALLKYQSRRQQTAASASASAGSGAPRLGVGSENTSPSYTPNNTNGNSFSAITTSSSTYFPPGPLSPAPLPPINTSLNINFSAGRYSLPAQPSPGYASPSSSILSPPYNDKSPSFVTPTDIKNHQEMQKHQQQQQQPQHGIPSAMLANNASIPMGPMTTISASGPSSAFEKQQVPPKKTKGITFLRPVSTLLLRRKGNNSVPDLIPLGRVAEEPAYDPRIKGTRVHDFSAPRSKRAPSSAIPPQTNSFHGHVNTSGGLHVYNLPKLSTSASTSTLVGPQPNSATSEAADPTAAVKDAASLPASLRSVPSTVSVGQPATGKSEDAFQETTTQEHTRTFSFKSRISRKISMSEISLHSSISRRMKSTSSRFSFDMIGAAKQEKIMEERHRQRQLERGEAPEEPAEVNAFVQGDDRFDDFDMDDFDYDNMMDDDGLEEEIPGLNLDYDEAEILEDEEHEDPFEYDEQYSGANNGYEAGNVSPVQEGLGHMTLADIEAADTLVASSAPTSSAVLDEVPDTATAISPVAHSLIDDNTASTNRDTTQDIVQDIAQDIPQETTKSTRFPLVSDPQCESRVVEQIIETPLPHSNRSAAATAKRDSQNFAAFIFQRSNPTSQLASPRSFGVQATPRDAEGRVIGFACSNETPPGTGKSFSGWGPCPGNIADNKTSTAVGALGSAADHPRESEEAQKSLDVMIARDVTPSGVYVRINSPLSSIGEAEPEAIPLEMQEQFQMRASANQRLGVLEGEENTFDANISNDLSGEFITDEFTTGNDASFDESIFDMDDTDQYGRPIPGAFAMAKQRLSESRDKLKRDSAALAPEPSLDVSNLQPEQSDSRPTLHPITIPSFYPRHHAECLQQISPENAATHDAIIAMGLSHMGLRNEIRGVGPETRPEDVMAYQAALAAAAQKAADAGKFQRHSWLSEVDDGNGQDRGQPIGQGNSAAATARAGAGDTNVEIDAADDLDLGGGFNMADYENDDMDDYFDLDQADDSKIIEEANASALANDYDGWYGQEFGFYSAPLNQAHQLNSAVKYEYSNGGFFGPAGMPTISRSDSGRVAVREPNLTPITERSEYSNRNSIMSLPGITVPTSAITSPGLSQLAMIADNEESMSMSTLLRLRSRAWGGGSQASSNHGSPRSERADGASSPLASFVGVSSGLNEHLHSMSAAGGRDMEPEKFESTNSLSGARTSIGVAPAVGGSGLRVLFSPVTSSGGEGAPDQTQTQVQGQTQTQTQTQTPIPTTAGFPPAREFPLASAASSAPPISLTLNTALSPGVTSNAVSENPLRHTEMLPLTRCALSLAQRPSPRLPSLTQSTSSNSQGPSEIEAPPFKNKESAATNHSGSSAAALVATSTTGPLVSEIPDTITEPENPNDDAPLSPLAQRLQDATEEALYTGGLAGRQSIVNAGFSPALRAKLLAKISHASPPSSGTTTAATSIPTAAGRGTRDTALSEPWDGSEKTPDAVLRMLDDAHKRLPVELRAPPPGASVVDLRPQRAMWASPGERIARARDAAADYAALEGRSASTHPAPGLAPFPILGTATTTATPATSGPDTEREERLRLFKERFEPGTRALPHSLPGLASLANERIEAAMARGAFSDIPRGPGVQRDERGGNNPFIDTTEYIMNNMLKRQDLAPPWIDKQQEITRATETFRNRIRTSWKIRLLSLIGSSSGRGASSLEERIARARANACAEVRWNPPPRGPTAGLGSVAAGATDDVVMKAGRGAGIPVEAGAVPDNNDSSPMVLSPPPLRDPNWEHNERKFLALSIAEVNALLRSYNLMAPDLAKKAYLSIDIELRLCYAEVAAQAEQALRTGETRPARVNGTGLGQILGRGAGWGFNLGADGGGPPERRVPDTPGSYGLRDMWRDLWGRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7L7</accession>
    <name>A0ABR3Z7L7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">quinol--cytochrome-c reductase</fullName>
            <ecNumber evidence="4">7.1.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">CYT1</name>
        <name evidence="18" type="ORF">Cpir12675_002899</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>a quinol + 2 Fe(III)-[cytochrome c](out) = a quinone + 2 Fe(II)-[cytochrome c](out) + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:11484"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="7.1.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome c family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.8" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000062">
        <property type="protein sequence ID" value="KAL1896192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="entry name" value="Cytochrome c-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.100">
        <property type="entry name" value="Cytochrome c1, transmembrane anchor, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002326">
        <property type="entry name" value="Cyt_c1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021157">
        <property type="entry name" value="Cyt_c1_TM_anchor_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10266">
        <property type="entry name" value="CYTOCHROME C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10266:SF3">
        <property type="entry name" value="CYTOCHROME C1, HEME PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02167">
        <property type="entry name" value="Cytochrom_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00603">
        <property type="entry name" value="CYTOCHROMEC1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="Cytochrome c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81496">
        <property type="entry name" value="Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="14" id="KW-0408">Iron</keyword>
    <keyword evidence="16" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="11" id="KW-1278">Translocase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00029351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1896192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="309" mass="33665" checksum="AB575E5E95AF8E87" modified="2025-10-08" version="1">MLTRSGLRSTRIFTQARTGFVNVAKRAASNSSNASEASSARLNMAAIASTGVAAGTMAWYYHLYGETADASTPADEGLIAPAGCSLRRGFQVYREVCASCHSLSRIPYRSLVGTVLTVDEAKAMAEENEYPGEPNEQGDIEMRPGKLSDYLPSPYKNEEAARFANGGALPPDLSLIVKARHGGCDYIWSLLTGYPDEPPAGAQVAPGMNFNPYFPGTGIAMARVLFDGLVEYEDETPATTSQMAKDVVEFLNWAAEPEMDDRKKMGMKVLVVTAGLFAASVWIKRYKWAWLKSRKLTYSPPAGDHKVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7Q4</accession>
    <name>A0ABR3Z7Q4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidyl-tRNA hydrolase</fullName>
            <ecNumber evidence="1">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_002713</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = an N-acyl-L-amino acid + a tRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PTH2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000055">
        <property type="protein sequence ID" value="KAL1896691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02430">
        <property type="entry name" value="PTH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1490.10">
        <property type="entry name" value="Bit1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023476">
        <property type="entry name" value="Pep_tRNA_hydro_II_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002833">
        <property type="entry name" value="PTH2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00283">
        <property type="entry name" value="arch_pth2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003314">
        <property type="entry name" value="PRK04322.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12649">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12649:SF11">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01981">
        <property type="entry name" value="PTH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102462">
        <property type="entry name" value="Peptidyl-tRNA hydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="232" mass="25117" checksum="D826CAD4A6CDFF3E" modified="2025-10-08" version="1">MSAIPPTEHLYNATVVVSTSLVVFLSGFVLGIYSIRGYLISPELAEERRRNLNDPVESEESDIDDELLLDHAPNWSNGLQADVRDGLRSRPEGDDAVTQKKEAADVSEECKLVLVVRTDLGMTKGKIAAQCGHATLACYKAITRSAQKSPLSKEAKILRQWENLGQAKIALQSKSEDELMTLLATARSLGVTSQVIQDAGRTQIDPGSLTVLGVGPAPKSEIDKITGHLKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7S2</accession>
    <name>A0ABR3Z7S2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002878</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000061">
        <property type="protein sequence ID" value="KAL1896232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="385"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="224"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="268"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="295"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="406" mass="40483" checksum="34C956C1E9F52DF1" modified="2025-10-08" version="1">MSSPSSSPSSSPLPTSSTLTATSLVALPTPLVHRADVNSPNHTIYFSSGSTSAITSPSALMEPSSNAFSQVTSKVSYATITPREVNSPVPTDLSVVDLADFTSSSSTSSSRPYLDINEAPSPVVSQITVPSSSVTTSAELNVVTAPAEIPSEYKTVTFTQCQSDAVVVSTAPESGDACTALYGLVPPDFSAIPTAAEASAITTTITGASAGNTIITIVIPANAASTTSTEPTTAPSVSTSDNASSTSVMLSAETLSSDSATSIKTNATPTSDSPSSSSTDTSFVASGTRSVPSVATTTATITTLTWPPVDSSSKLSSSPTVVSNIGGKNNDTRGSSGDGGNGGNDGDSGDESGDGQHSDSVSEGDLVNEAHDENSGTASVLVNAIVWPIVGVVTLAGIGLLVATLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7T3</accession>
    <name>A0ABR3Z7T3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RNA cytidine acetyltransferase</fullName>
            <ecNumber evidence="9">2.3.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">18S rRNA cytosine acetyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 15" type="primary">NAT10</name>
        <name evidence="15" type="ORF">Cpir12675_002671</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a cytidine in 18S rRNA + acetyl-CoA + ATP + H2O = an N(4)-acetylcytidine in 18S rRNA + ADP + phosphate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:51424"/>
            <dbReference type="Rhea" id="RHEA-COMP:13575"/>
            <dbReference type="Rhea" id="RHEA-COMP:13576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:74900"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a cytidine in tRNA + acetyl-CoA + ATP + H2O = an N(4)-acetylcytidine in tRNA + ADP + phosphate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53876"/>
            <dbReference type="Rhea" id="RHEA-COMP:13670"/>
            <dbReference type="Rhea" id="RHEA-COMP:13671"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:74900"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Interacts with TAN1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
            <location evidence="1 9">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000054">
        <property type="protein sequence ID" value="KAL1896723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:peptidyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03211">
        <property type="entry name" value="RNA_acetyltr_Nat10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033688">
        <property type="entry name" value="NAT10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007807">
        <property type="entry name" value="TcmA/NAT10_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032672">
        <property type="entry name" value="TmcA/NAT10/Kre33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013562">
        <property type="entry name" value="TmcA/NAT10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027992">
        <property type="entry name" value="tRNA_bind_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10925">
        <property type="entry name" value="N-ACETYLTRANSFERASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10925:SF5">
        <property type="entry name" value="RNA CYTIDINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13718">
        <property type="entry name" value="GNAT_acetyltr_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05127">
        <property type="entry name" value="NAT10_TcmA_helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08351">
        <property type="entry name" value="TmcA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13725">
        <property type="entry name" value="tRNA_bind_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TmcA/NAT10 N-terminal" evidence="12">
        <location>
            <begin position="9"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="TcmA/NAT10 helicase" evidence="11">
        <location>
            <begin position="281"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="13">
        <location>
            <begin position="540"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="domain" description="Possible tRNA binding" evidence="14">
        <location>
            <begin position="778"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="435"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1019"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="1060"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="286"/>
            <end position="295"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="480"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="641"/>
            <end position="643"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="648"/>
            <end position="654"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="743"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF13725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1896723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1070" mass="118781" checksum="05D344FEE90EE442" modified="2025-10-08" version="1">MPRKAVDQRIPALIRNGLQEKKRSFFIVVGDRAKDVIVHLHYIMSSMDLTQNKSVLWAYKKKLLGFTSHRQKRENKIKKEIARGIREANEEDPFELFISVHNIRYVYYKETDKILGNTYGMCILQDFEALTPNTLARTVETVEGGGLVILLLKGMTSLKQLYTMSMDVHSRYRTEAHDDVVARFNERFLLSLGSCQCLVIDDELNVLPISGAKDVKALPPPDLDQPETPAQKELADIKESLQDTQPVGSLVTLAKTVDQAKALLTFVDAIAEKTLRSTVALTASRGRGKSAAMGMAVAAAVAHGYSNIFITSPSPENLKTLFEFVFKGFDALGYADHADYTIIQSTNPDFNRAIVRVNIHRNHRQTIQYIRPQDAHVLGQAELVVIDEAAAIPLPLVRKLMGPYLVFMASTINGYEGTGRSLSLKLIKQLREQSRAPGANAAADTEVTDRATGKASKSDNAAAYHGGRSLREITLSEPIRYAKGDSVEKWLNGFLCLDATLPKAKSRSQGCPDPAQCQLLHVNRDTLFSYHPVSERFLQQMIALYVASHYKNTPDDLQLMSDAPAHELFVLVPPMADNAQKLPEPLCVLQVALEGQISKQSILNSLSRGQRPSGDLIPWLVSQQFQDDEFAGLSGARVVRIATNPEYVSMGYGSRALELLVDYYEGKFASLSEGDELPAEPTMPRVTEGELQGASLLNENIRVRDISKMPPLFAKLDERRPAVLDYVGVSYGLTAPLHKFWKKSGFAPVYLRQTANDLTGEHTCVMLRPLENSVDRSWLGAFSRDFHKRFLSLLSYQFREFPAITALSLDESASAGAKLDGAEPRPLAKLDLDEFLTPFDLKRLEAYSNQMLDYHVILDLLPSLSQLYFSGRLRSSIKLTGVQQCILLAIGLQRKDLDTVSSELSLPSSQLLAMFIKIMRKITAHFAGLVASEVEKSMPAREGLGVSLENATGVHDDELVDVKFNPLEQSLQADLNEGGNEALAELRKKQRALIDSLPLDQYEVQNDAPGWQEAEATVRSASKRGVANPTVSVKNVRDAKRKAAGPSVEEVYEKANERGPKKKRSKKDRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z817</accession>
    <name>A0ABR3Z817_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">37S ribosomal protein S16, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MRPS16</name>
        <name evidence="5" type="ORF">Cpir12675_003003</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000065">
        <property type="protein sequence ID" value="KAL1895963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00385">
        <property type="entry name" value="Ribosomal_bS16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000307">
        <property type="entry name" value="Ribosomal_bS16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020592">
        <property type="entry name" value="Ribosomal_bS16_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023803">
        <property type="entry name" value="Ribosomal_bS16_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00002">
        <property type="entry name" value="S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12919">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12919:SF20">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS16M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00886">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54565">
        <property type="entry name" value="Ribosomal protein S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00732">
        <property type="entry name" value="RIBOSOMAL_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="128" mass="14169" checksum="C5A2BECF65EB0650" modified="2025-10-08" version="1">MVVKIRLARFGRRNQPVYNIVVAQARTARNSRPLEVIGTYDPIPRADPYAAAAAATQGAPPPKLHKDIQLDLTRARYWLGVGAQPSEPAWRLLAMVGLLPNKIWGKPKPSTMPLGGEPIEKVQQKQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z838</accession>
    <name>A0ABR3Z838_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">rRNA-processing protein FYV7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003018</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000065">
        <property type="protein sequence ID" value="KAL1895978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41805">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41805:SF1">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN FYV7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="249"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="303"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="324" mass="35180" checksum="4BBB73FEEABBF3E7" modified="2025-10-08" version="1">MPKVSISKKPAVIGGAGVKKAKHGFRVGPQNLPDGPWKRKLEKAKKNLIHKAKVKKQYAKIKAQVAKDRPRRASATVADPDAAMNPKEALIPTNPRSDDGNEQGEESDEALTSGSDDDGGDDGVSEDEDTDAEDGEDSGNDSGGEPRAEDSEEESDDEDKDGSYEKPLKRAPKTPKPTSNDTDPNDTMHPSRKHTKAHPARPGYFDKQIAQADAKKRAAEERASAIDTKRKEREAAILARQKRRKEFGRSIGIGTRSSGPARGRGRGYGFSSRGGRPDYSEDGKRKLGRESELLLERVQRLVGGNNNSNRGSSSGGRSRGRGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8L5</accession>
    <name>A0ABR3Z8L5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">carnosine N-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_002520</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carnosine N-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.22" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000050">
        <property type="protein sequence ID" value="KAL1896995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012901">
        <property type="entry name" value="CARME"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12303">
        <property type="entry name" value="CARNOSINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12303:SF6">
        <property type="entry name" value="CARNOSINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07942">
        <property type="entry name" value="CARME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01296">
        <property type="entry name" value="N2227"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="337"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="338"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="415" mass="46083" checksum="2F5322EDF44BC6F1" modified="2025-10-08" version="1">MAKPHTEDWRGLEGSAIKDEEEACVLFSALDSFVRYARTAHFSVTHLRRQSFYALPEAHWKMLAAPPFNFLDTLMRTDDAIDSNAELARTIARFGLKNFVHLDLPEGPDADVSIPPRWAGVASHSDIDKARSTIRQFYRDWSEAGKVERDASYGPVIRALEKERALHTGQGPLDVLVPGAGLGRLVYELCCHGHNAEGNEISYHQLVASSYILNCAKTANQHTIFPWVHTFSNHPTRDSHLRSYTVPDVHPAAHMRSLKEQGKLVGEMSMCAADFICLYGDDEHKESYDAVATVFFLDTAPNLIRYLEVIWSCLKPGGILVNMGPLLWHFENNAPGNHGKDTDGDGLHESGTSSGIADPGSFELSDDEVMALLTKIGFMVESRETGLAAPYITNPESMLQTVYKASTWVVRKPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8S4</accession>
    <name>A0ABR3Z8S4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Calcium channel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">CCH1</name>
        <name evidence="18" type="ORF">Cpir12675_002775</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000057">
        <property type="protein sequence ID" value="KAL1896486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050599">
        <property type="entry name" value="VDCC_alpha-1_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002077">
        <property type="entry name" value="VDCCAlpha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45628">
        <property type="entry name" value="VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45628:SF7">
        <property type="entry name" value="VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00167">
        <property type="entry name" value="CACHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 14" id="KW-0107">Calcium channel</keyword>
    <keyword evidence="4 14" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13" id="KW-0407">Ion channel</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="8 14" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="364"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="403"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="542"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="565"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="684"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="707"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="839"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="862"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="972"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1213"/>
            <end position="1240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1255"/>
            <end position="1277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1289"/>
            <end position="1311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1346"/>
            <end position="1370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1468"/>
            <end position="1490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1548"/>
            <end position="1569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1581"/>
            <end position="1601"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1613"/>
            <end position="1632"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1668"/>
            <end position="1692"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1772"/>
            <end position="1794"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="17">
        <location>
            <begin position="1806"/>
            <end position="1841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="267"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="2007"/>
            <end position="2073"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="2091"/>
            <end position="2140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="10"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="44"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="213"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="2018"/>
            <end position="2035"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="2045"/>
            <end position="2068"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="2091"/>
            <end position="2121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="2122"/>
            <end position="2133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1896486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="2171" mass="243500" checksum="DBA684501668C4F8" modified="2025-10-08" version="1">MDSDVAALNLAQQQPGTPDRSSGKQTVASSSKHGSPSHLAGPTSDAAGSSSLSQKSYSDYPYPQLSMQNASSSTGSPRAHRTPPVPVPPLTTSWSTPAKKAQVTKRSNSPIDAASVSFALPPNIKQDRSISPDSAIFNESGRYYDDPYHNPESDAVPLTSRAQPIDGTASGATLQPRSPADSVRRDSFQTVSSYANSPVKGQMLSADDALRPNRQTGYGSSLTPSGSVRRRSRSPSATGALQRAGSAMRAMSERVVNVSGEAEVVEQQLSMNRKSRAPSDDERTSPHVSPVMSPLGMESGYVSQMYSHSPKEKLGNPFEETVPVSESTVPMPNPLKGRSLGIFGPENPLRKWLCTILVKPITEIFILLSIILQLILLTVDAAPNVFDDGRGRPQFWGESRMDWAYLVLFIIWSLEMGAHVIVSGFILNAAEYSTIDRQRGVRANIVDKYTTFFQPESHKGKASRTSQAPPPLLRTFTALADNASKDDQKKWQLARRAYLRHGFNRLDFVAVMSFWLSFSLSVTGNEDRHDIYIFRMLSCLRILRLVAITNGTAIILRSLKKAAPLLVRVVFLLIFFWVLFAIIGVQSFKSSLMRHCVWIDPLDPKNISATYANEFAFCGGHLDNTTGLKMPWVYSETGDSLDDLKNGISKGKGYICPRGSYCLQQSNPHNGTVNFDNLLNSMELVFVVMSANTFADIMYYTTNSDYLAAALFFVAGLVIMMLWLTNLVIAVITSAFQVIRTENQGSAFSSKQDIQPETNETQIWQATSLQKFYEKTKFVWISFIVSDLTAQACRTWSMSDETAKSIDNISIIATIALDVEIIFRFIANVKHFFRSYVNLFDFVLAIATTAILLPPIHDDAVLYGWLSVFQILRIYRVVLAVPMTRKLILLVLGDASGIANMFLFVYMMTFFMAIFAVQLFRGAVPEEIDGEGIDITFGNIYNSFLGMYQILSSEDWTTILYNVTSVGKGTSMAVFGAIFFIGWFFLSYFIMINMFVAVIQENFDVSEDEKRLEQVKAFLQRKELGQTTSHQISLATIFSIGRRQKPRDPLDYGPATMEMLLKDALVQEFLAETDNADDSTGSGHGHLNAATTTFLSGGSRGDVKPGFFSSLWGKMVTLFTSREPNPFYSNIRFDPPAGGDTIGGSDPRSIAKKAVLATNARKRAQREYIARYPRYNNSLFIFSPKNPIRRFCQLIVGAGRGSERFEGREPNKYAWYSFSFFIYICIIGMVLLACVATPLFQRQYLEDHDITGRPWYTWCDVFFAGIFTLEAVIKVIADGFFWTPNAYYRSFWGFVDGVVLVTLWIYILTLFANDGAVSRAIGAFKALRALRLLNMSDDARETFHSVIVGSFKIISAAFVSMSLLIPFAIYGLTLFSGKLLSCNDGDSDIVMLSECFGEYSNTPYADDWELLSPRVVNNPYFNFDNFGASMFTLFQIISQEGWIDVAFSTTAITEPGYQPISANRPGNAVFFVIYNLMSTVFVLTLFLSVFMRNYTEQTGVAFLTTEQRSWLELRKILRQVSPSKTTHNDHAKPWRRWCHKRAIEKRGVWYSLITTILVLHLILLMTEYYQEPDSWTIGRDILFMVFSLIYVINISVRILGLGWTRFRRSSWDLYSLFVVSGSFITTSALLISSTESDTYVQLHKAFLVAIVLLLIPRNNALHQLFKTAAGSFSAIINLLATWFVFFLMYAIAFTQAFSLTRWGERTSSNINFRNVPNALIMLFRVSMGEGWNQVMEDLADIVPPLCVDEPRFFDSDCGSKPWARFLFVSWNILSMYLFISLFVSLICESFAYVYQKANGLALLEREEIRRFKQAWRLIDPHGTGFITKEQFPRLLGELSGVFEMRVYPHEDSVGQIIEDIRDTSAESRHTAFGNINQAKPEINLERLNTRLSQLDVAEIRRRRRRFNIFFEEVMVAADPDKGISFTSVLMILAHYKIISESKSLRLEEFLRRRARLQRVEEEVRRRVVVGFFNMLYWSRKFKRHIEMKRASRMGTVPSLPAIQINRDGNASRSEENDGQQNIKDGVSSTISNSPTLAVADGSARSSSIHGLSGSNGSNGGINPLSPSGDITYDADSRRTWNGGLAGLHLDTSQHPLSLPRTGSSNSPSTQFASGGSFTFNVRETRPTAGDRRMTAVNSSSAVQDMLDESVWIESLRRSTTVRRNQSRSGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z955</accession>
    <name>A0ABR3Z955_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">tRNA methyltransferase ppm2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PPM2_1</name>
        <name evidence="4" type="ORF">Cpir12675_002719</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">tRNA modification; wybutosine-tRNA(Phe) biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. LCMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000055">
        <property type="protein sequence ID" value="KAL1896697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46529">
        <property type="entry name" value="TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46529:SF1">
        <property type="entry name" value="TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13418">
        <property type="entry name" value="Beta-prop_TYW4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="578" mass="63299" checksum="03F7E1337A94CF85" modified="2025-10-08" version="1">MMQKKKQIVTQIPELAELLGNNFKTSQKETGVILESPKYCQIACDLRELDIVTGMIEEIIDLQNSHVLFVAEVSITYMDNKSADNVIRWASTIPSAEFCLLEQILPDGPEYPFAQNMLAHFDKLQTSLKSVSRYPTTSHQEARFKVLGWPYSRAWNLWEAWGDSFFMSAEDRANLDHVEPFDEWEEFAIFGAHYTVVHASNMAPICHGDLKKQNIYDCDTTPVQEIDVSFLPATGPQVHRHHGGATIIDREQSGDVAFATFFGQGVTNRSSSVDFYSLETILDPEWFGPPPRVCFSTTDLGLCVLLAGGRASPAKAMSDVWILEKKSNKWSEAPYLPKALYRHAVTRLGDSGLALLVGGKTGVHEISESIFLYGGHNGGWAECRAIGDVPLPRFGAVLGCFSNIHGFLSGGITADGLVDQSTYQWILDLEERTVSFARVQCNPALSRFGALVISTAAGPVVAGGIVGNHLIPTASDILLVNEKKDNKAGASENGDSSALTITCLRDMQLTDNCPHRPFFIGSSGLEKNGQVTIIGGGATCYAMGSYWSPGQYGFHILGGQPVSVPFAESFQIKQQNDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAW2</accession>
    <name>A0ABR3ZAW2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mediator of RNA polymerase II transcription subunit 19</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Mediator complex subunit 19</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MED19</name>
        <name evidence="11" type="ORF">Cpir12675_002755</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Mediator complex subunit 19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000056">
        <property type="protein sequence ID" value="KAL1896659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013942">
        <property type="entry name" value="Mediator_Med19_fun"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08633">
        <property type="entry name" value="Rox3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0010">Activator</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="284"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="20"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1896659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="348" mass="37734" checksum="3100B4D171885F4F" modified="2025-10-08" version="1">MNCHPQTPQSPSQLSLAPSDSFNGMPSGSTLGTLPTPAHSVNGGNSQQEYVMDDLISKRKRSIDDTGDNAFKRLHIDTGTVGIEALHEEVGPKYLLLKQPVPAIKYPVSNDFFSMFGLSTVATELARVKPNGDKNILRKSFKNQLKRLKIDGGYDTKKDQREENDPDGLLNMIFMPEDVWYANNVKEKELMDGFSAPTTASLSRASVMSRGKIRKEAWDSYILGSLDSGLSFMENNIIPSSAPNTPAGSASGMLAKQKISSNGSSGLNGQVADPLRPRRNIKKRTYADSGYEGYPETFNEDDPADGGYSTGDGDDRSGQKRRKKNAGNMASIPTGMRQQAYGPGVVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBR5</accession>
    <name>A0ABR3ZBR5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000036">
        <property type="protein sequence ID" value="KAL1898111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045713579" evidence="1">
        <location>
            <begin position="17"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="506" mass="48658" checksum="C7EB4414860509DF" modified="2025-10-08" version="1">MRFNPAIVVLAGSAIAAPVIEPSTALGTCLGAPTIPAEGKDLGLGLGDIKEREVAIAELTRRLETSSLSNLTSKAGISLPDDVVDKANKLSANLPDLASVIVGIIINLRESNPLLKNTPLNGVVNLALPIVEGVLSSVNVKSISARELDNRSIELVTSLLSKILGVATGLLGSVTSLGGSGGAGDLLGGLTGGLTGGAGGAGGAGDLLGGLTGGLTGGAGGAGGAGDLLGGLTGGLTGGSGGAGGAGDLLGGLTGGLTGGSGGAGGAGDLLGGLTGGLTGGSGGSDLTSLVTGALDGGSTDGLTSALTGAITKGSGLSAATMLAELPGIGSLPDLTNAESITGNLGNITGSGNSTISTQVLDKIAELIDFSLNGLSTVAAIPESVVPAPLNAPFRALAVELDALKPSVDSLKDILSGTSDLASTSDLTKLYDVLDKVYNGLLKLNDEIIPKSLKPATVTGLAGLLSVIKTVLTVSSGYIATASQAVKNAGGNPKGLTDAMGLIKDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBS0</accession>
    <name>A0ABR3ZBS0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000036">
        <property type="protein sequence ID" value="KAL1898116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="503" mass="54430" checksum="25BC2101E3337E09" modified="2025-10-08" version="1">MPSFMFNPFGSSHRSGPRIVNPMLSSLPKPDKSQEPAPCLPSLPDLSSSDGDSLIEAARQDIHPAVRPGKLKTIGGSDSADKTNKGDTYKVPDVDFGPTFNFAAKDLPKDKLRAIIGDAYYDSRSSSTNDSKHKSMNQQWRRLNSSAGMTSRPGTVASHYRNISRESLPGHDHPHLAHRRRSSSNLMASPPAANYNYAAGVTPSHTPPRSGTALSQTPQRLLTPESIEQAPHSRSNSYSHVHSHLNSQPHPHSHSHSHSHSHSHSLSHSHIRKLSAESRPYSRAATLIEYPTRPELVSNLSAREQAHVARLTGGPLISLVTTPSRQSPSSAVGGTSTPGRGHAHSPSVGLVGAIDARQREKEQLKASGAYNPSVAYGLRERQQQMAMKQMQIAQAQSLAFQNQQMQMQFQAQWEQQQIQQQQQMMLAGSQGMATPRAMSSMGGSPTGYEAAPAMHGNMAVPSALSNRRSMYGMSTNGAMADGMEGMGMPQQRGHFVAAGARGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDC5</accession>
    <name>A0ABR3ZDC5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome c oxidase subunit 8, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cytochrome c oxidase polypeptide VIII</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_001788</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Mitochondrion inner membrane</location>
            <topology evidence="1 10">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome c oxidase VIIc family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000030">
        <property type="protein sequence ID" value="KAL1898681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.49.10">
        <property type="entry name" value="Cytochrome c oxidase subunit VIIc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004202">
        <property type="entry name" value="COX7C/Cox8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036636">
        <property type="entry name" value="COX7C/Cox8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13313:SF0">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 7C, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13313">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT VIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02935">
        <property type="entry name" value="COX7C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81427">
        <property type="entry name" value="Mitochondrial cytochrome c oxidase subunit VIIc (aka VIIIa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1898681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="75" mass="8111" checksum="0FA0EE567A941FAD" modified="2025-10-08" version="1">MIAAVRSQSTGQIARRAFSTSRAQMSSPYHYPSGAGSNLPFNPKSKWFGPGFVLYAVAGFGAPFGISVYQTYRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDF8</accession>
    <name>A0ABR3ZDF8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Calcium-transporting ATPase</fullName>
            <ecNumber evidence="14">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">PMC1_1</name>
        <name evidence="19" type="ORF">Cpir12675_001983</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the hydrolysis of ATP coupled with the transport of calcium.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18105"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="14">Membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="14"/>
    <dbReference type="EMBL" id="JAWDJO010000034">
        <property type="protein sequence ID" value="KAL1898357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02081">
        <property type="entry name" value="P-type_ATPase_Ca_PMCA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006408">
        <property type="entry name" value="P-type_ATPase_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01517">
        <property type="entry name" value="ATPase-IIB_Ca"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093:SF369">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08282">
        <property type="entry name" value="Hydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 14" id="KW-0106">Calcium</keyword>
    <keyword evidence="3 14" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="12 14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="276"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="313"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="480"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="521"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="954"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1023"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1104"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1144"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="18">
        <location>
            <begin position="245"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="16">
        <location>
            <begin position="346"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase C-terminal" evidence="17">
        <location>
            <begin position="981"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="212"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1234"/>
            <end position="1292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="89"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="1234"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1250"/>
            <end position="1259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1898357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1332" mass="143538" checksum="62703BCB46686040" modified="2025-10-08" version="1">MSDQDPKNSSVPDISTRDKAPTITIDTAVLSSDGPAARNADDTAASTTAQPTAESQHNDVHESRGSPPSSPLNLTTPNTTRSFLAVPNNLRSRTGSVDSVDASSHGGTTLTPSGASFVSDTKKSTPISNEFIINDKDALKPDAGKEVDFHVENNRFAFVPGELNKMFDPKSLSAYYALGGLVGIAKGLRADTKSGLNPDEIHVEGSVSFEEATAHKATPTHRKPVDAPAVAHEAPSATNHDGTFVERKLTFGDNRLPDKKGKSLLQIMWITYNDKILILLTIAAIVSLAIGLYETFGQDHEPGSPGIEWVEGVAIIAAIAIVVIVGSLNDYQKERQFAKLNRKKSDRLVKVVRGGRMQEISVYDVLVGDVVHLEPGDMVPVDGILIEGFNVKCDESQATGESDIIKKTSGYQVFEAIESNGNLKKLDPFIQSGARIMEGVGTFMCTSTGVYSSYGRTLMSLNEDIEMTPLQGKLNVIATYIAKIGGAAGLLLFITLFIKFLANLPGSDKTPSEKGEQFLDIFIVVVTIIVVAVPEGLPLAVTLALAFATTRMLKDNNLVRHLKACEVMGNATAICSDKTGTLTQNKMQVVAATIGTSSRFGKDDNSEILPQTFASSLSEPVKKLLVDSFALNSTAFEGEVEGKPGFIGSKTETALLILGRDYFGMGDVAQERDNAKVLQIIPFDSGRKCMGAIVQTPSGGARLLIKGASEIVLGQCTQLLRNPTSDLSLQPMTSAINKEFMAVIDGYANRSLRTIGIAYRDFASWPAEGLRRNEDDNDIRFDDLFQQMTFLGVVGIQDPLRPGVPEAVALCQKAGVTVRMVTGDNRITAAAIARECGILEGEGLVLEGPEFRNMSKEKQNEIIPRLRVLARSSPEDKRVLVKRLKGKGEIVAVTGDGTNDAPALKTADVGFSMGIAGTEVAKEASAIILMDDNFTSIINALKWGRAVNDAVKRFLQFQLTVNITAVLLTFISAVASDEEASVLTAVQLLWVNLIMDTLAALALATDPPHDSILDRKPEPRNAFIISLTMWKMILGQAVYQLVVTLVLYFGRNSVLPSITPKYTHDEVSTLVFNTFVWMQIFNQWNNRRLDNGYNILEGVTKNPLFLGINVAMCGLQVLIVFVAGPVFNINDPRDGNGKDPQGGALWGIAIGLGFLSIPFGMLIRTIPDAWLAAVVPQFIKNRASRAPGLTVSDEETFQQFPPEYQDVRDELEFIKKVKGGRLTNLKFAIAHPRQRFAHSRNSSRSRMSSATVTQVQSEMTSPPPATQQAAASKSGTAAGENAAVPSPETSHRLRARTNSTLGAPSVMAGIVAAGIATSWQAGDRKATDGEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDG0</accession>
    <name>A0ABR3ZDG0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000035">
        <property type="protein sequence ID" value="KAL1898322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="105"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="549" mass="63707" checksum="CD4BBB0390B371D0" modified="2025-10-08" version="1">MTMDPPSMSEFASDRFFSKLQEHETQNAASSTAVIPTSSTFILPVRDGRNIDGAPTFAVDSKQKARFGSTLRSKLLKTHSGSESDFVNYSARNDYSCRRSIQPLDILFRNLPVELQLQIFELLPFSDIINLRLVSRSWHEMISANQIALARFHLKQDIPAYALRLYPIPNSPDDWFYHMCALWSRLHIAAKMAHLTCEWVMTEIFLRRTPCQRVEFASQRERMRRRLIPLMLTIFHFFESYRQLHLEFIQNNPGYGLRFEPYTVNPIEAKIMATYDDYTLLRVHEVFPVVISTFCRQLRPPTYVGTIERNIRGYIKDKLSDEMTAAILCIGGPYQMIRFWEIIGYNHRRNAVDHWFDDLMVDRRRLMQIPSNGTGLISNQTPPPPMPQAPTKSKHRLFGRLSLKKSNATFRETAKHVEHALPVPAVPSSFQITGGPSHQHEYNPLAPENDPLLRGRPMAPLPPQYVKQLLPDMPVLQQIWMVTAEALIMERRIVERPQDIKRNGHVLFDLIREPTMADEDEIWYGRETLDSMQPLVKHMDEMDIDSPMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE37</accession>
    <name>A0ABR3ZE37_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001777</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000030">
        <property type="protein sequence ID" value="KAL1898670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="155" mass="18202" checksum="E6879B57E8745BC9" modified="2025-10-08" version="1">MLQRSPQVSRATARAAREAAVAADAIDKAAERATARAKVMDLIERYPAKKEWPPDFRQLTSQLQFRLEKKWKRRAQLASSSPAQTKRLKLLQYFAITFVILYVFFFGELELWGQKYRFTNELNQKFGTFFGTLSPEKRYERRRDVLDPLPRDDPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEK8</accession>
    <name>A0ABR3ZEK8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_001720</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000029">
        <property type="protein sequence ID" value="KAL1898717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14723">
        <property type="entry name" value="ZIP_Ppr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052202">
        <property type="entry name" value="Yeast_MetPath_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782:SF1">
        <property type="entry name" value="PYRIMIDINE PATHWAY REGULATORY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="69"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="157"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="447"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="797"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="27"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="157"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="186"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="838"/>
            <end position="851"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1898717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1001" mass="109549" checksum="89DA570A7CE563B9" modified="2025-10-08" version="1">MPMKRPRESSPDPTLMDEKLPTAAMDAEATPASTPALPLARSHHTSKPSQSSVTTNNTSASSNFRNVSACNRCRLRKNRCDQRLPSCASCAKVSVACVGYDPITKMEIPRSYVYYLETRVEGLEALLRQHDIEVPAADNLDMCSRIGYGLQNMRSAVTPTPRTVGGPTATTATDTADVDSVTTSALSKSPSTNQTGGMPNIMSASKPKSLASTSGVSFARVIFAAVQHSVSDGPGGAVQATTSSSMATPVNDTVRDMGHNATSMRDSFFGLHTKPSIRPAPFPPKAVASHLVNLYFEHANPQIPILHRVDFMNTFEQAYAPGHICGPRELYLLNIVFAIGGSVIVGEPVKLQTQAGLGGQQFSGDSPLPSPLTNSGRQAQPEEYHASAIVHLEACLGNSTGSLDVLQAVLLLANFALLRPVPPGLWYIVGVAVRLAVDLGLHYEDGTDIDSQTTDGSPDIASPAPASNTSCGDRGKRMYVRDMRRRLWWCTYSLDRLVSTCVGRPFGISDLLITTEFPSYLDDAYITPEGFREPPDASPKPSYKHVSIHYLKLRLLQSEILQVLQFNQTRVARENGQNMHNNAIQSQLVSPFLARFDSFRSWRIDIDRRLYQWRASAPTRDTTGVAFSTEFLELNYWQAIILLYRQSLSVPALFEGEYNPSREVDSPSNFRAESVEDEDRVYLKVAEAGQKILRIYRQLHLDSLVSYTYLSTHHLFMAGVSYLYAIWHSPIVRSRLTMEEVDFTVLAAKSVFTDMIDKCPPAETCRDAFARTAKATIKMVNSQGGFGTPVAKRIRRSRATRDWHSAMGEDTDSSKSLYSHSHGRSQDQPVNTTGFHFDMSMSDALSSPSLSTGGELADASPQQQFRHSRTAGTGGFDVDAMNSIMGSASGTSPQDQPALEVPLMSAGSNVAINACRPVPPAFMSPQQQQQVSQTMDYSNELDMDFLSSLAVSGADLTQIDRPPVDLGFGLNWDGVYHDFTNNQRVNLFDNFFFGSQNSGAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFV3</accession>
    <name>A0ABR3ZFV3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PTC2</name>
        <name evidence="13" type="ORF">Cpir12675_001896</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:47005"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000032">
        <property type="protein sequence ID" value="KAL1898429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF565">
        <property type="entry name" value="AT28366P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="12">
        <location>
            <begin position="23"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="386"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="403"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1898429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="445" mass="48198" checksum="B1FBE3532B1524B8" modified="2025-10-08" version="1">MGQTLSEPVVEKTSEKGEDSKLLYGVSAMQGWRISMEDSHINVLDLLAATKQTSTVEGQMSLFGVFDGHGGDRVAQFSGKHIHEILVKQDSFKEGNFKKALEDCFLATDRAILNNPRYEDEVSGCTACVALVVGDKLYVANAGDSRSVLGIKGRAKPMSNDHKPTLESEKARITAAGGFVDFGRVNGNLALSRAIGDFEFKKSADLPPEQQIVTVFPEVETHQLTEDDEFLVVACDGIWDCQSSQAVIEFVRCGIAAKQDLDKICENMMDNCVASSSETGGVGCDNMTMSIIAFLNGKTKEEWYEQVAQRVADGDGPCAPPAYAEFRGPGFHHGYDEVEETYEEDKFKAHRIGLGNYPGRIIFLGDGNESNMSLENEDAEMFDSIEEEKDLQSQIPKDNSPKAAADISADSSAGNGDATTTAAADKIQTKPQSITAAAVNGEEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG35</accession>
    <name>A0ABR3ZG35_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001317</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000020">
        <property type="protein sequence ID" value="KAL1899641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025239">
        <property type="entry name" value="DUF4187"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039249">
        <property type="entry name" value="GPATCH11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21032">
        <property type="entry name" value="G PATCH DOMAIN-CONTAINING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21032:SF0">
        <property type="entry name" value="G PATCH DOMAIN-CONTAINING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13821">
        <property type="entry name" value="DUF4187"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01173">
        <property type="entry name" value="DUF4187"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="2">
        <location>
            <begin position="95"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="353" mass="39849" checksum="6EDAF9FECC4C2AE1" modified="2025-10-08" version="1">MSSHLRRPTEVPAYAAQNRDSSNVNQHEDDDDYLTMAILEPTEPVKETSFQRSQRLKKEAIVRGQPKSKAEIAAEEAAARDAALSTSLLDAPNAKKSKGLAMMARMGFAGGGLGKKTDLGKGSGRAEPIRVEIKNDRGGIGMESERKRKLREEGERLEEECDGVSKKAKVLDPLEYRDQLARERERERVERQVLAAQRMALRLYEEKTESETDIPTRPGPKVSTGESQADSIKSINVLWRGVAKARQDAERQRLLKRRLEESLSAMYGGGETAEDGDDRMALGKDVSPLLPLDQEDADEDEELREFENLEPGRRLNRLLVHLREEHRYCLWCKYTYPDVEMEGCPGITEEEHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGV2</accession>
    <name>A0ABR3ZGV2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="15">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">SPB4</name>
        <name evidence="19" type="ORF">Cpir12675_001169</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits. Binds 90S pre-ribosomal particles and dissociates from pre-60S ribosomal particles after processing of 27SB pre-rRNA. Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal formation of 25S and 5.8S rRNAs through the processing of pre-rRNAs at sites C1 and C2.</text>
    </comment>
    <comment type="function">
        <text evidence="15">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">Component of pre-60S ribosomal complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="15">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="15"/>
    <dbReference type="EMBL" id="JAWDJO010000017">
        <property type="protein sequence ID" value="KAL1899948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17960">
        <property type="entry name" value="DEADc_DDX55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056330">
        <property type="entry name" value="CTT_SPB4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025313">
        <property type="entry name" value="SPB4-like_CTE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13959">
        <property type="entry name" value="CTE_SPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23681">
        <property type="entry name" value="CTT_SPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01178">
        <property type="entry name" value="DUF4217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 14 19" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 14 19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="8 15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="17">
        <location>
            <begin position="45"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="18">
        <location>
            <begin position="285"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="568"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="617"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="570"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="628"/>
            <end position="637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1899948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="637" mass="71251" checksum="48E97553F7A71BF8" modified="2025-10-08" version="1">MSREKKADPRAWKTIQPALPSWVLDYAEASGFAKMTAVQASVLPQWISKRGTDVVVEAVTGSGKTLAFLLPICVRLLGLGEPTKRHNIASIIISPTRELASQIHQVLLSLLAFHPESAEMLPFLDPENEEKRPVTTTPVIVSQLLVGGSVTPAADLAFFMRTSPNILISTPGRLVELLQSRHVHCPQSSFEMLVLDEADRLLDLGFKQDIQRVLGILPKQRRTGLFSASVSEAVSEIIRVGLRNPVKISVRVKSLRDGGIIEDRKVPASLEMRYIATPASHKLPALAKLLEKMEKTPQKTIVFVGTCAQVDYFQYILPLMLPKCYTTIPLHGKHATNVRERNFTRFVTSTSPSVLFTTDLAARGLDIPQVDLVVQIDPPSDPKVFIHRNGRSGRAGRKGLALVMLHSGHEETYTEFLEIRQTPIFPLTTPDVSIAPDEAARTTEIIRTLARSDRAVYDKAQKAFVSWVRSYTKHAASSIFRAQDLDWADLAEAWGLLRMPRMPELKTWDGDRMLGQSIDWDTFAYKDKAREKLRLEALAEEKADGGAKAAAAKAERLLKRKNNEAWSLKNGREDVRSDRRDKRQKKTEAKRMATMTEAEKVEKADLDMMLSKIREQNATIKTMSKEENAEEFGGFDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGX6</accession>
    <name>A0ABR3ZGX6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Vacuolar protein sorting-associated protein 41</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">VPS41</name>
        <name evidence="6" type="ORF">Cpir12675_001503</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000024">
        <property type="protein sequence ID" value="KAL1899310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057780">
        <property type="entry name" value="Beta-prop_Vps41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045111">
        <property type="entry name" value="Vps41/Vps8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING VPS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 41 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23411">
        <property type="entry name" value="Beta-prop_Vps41"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23556">
        <property type="entry name" value="TPR_Vps41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00299">
        <property type="entry name" value="CLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vps41 beta-propeller" evidence="5">
        <location>
            <begin position="297"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="Vps41 beta-propeller" evidence="5">
        <location>
            <begin position="500"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="3">
        <location>
            <begin position="1100"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="575"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="698"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="790"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="55"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="98"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="121"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="271"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="705"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="803"/>
            <end position="818"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1409" mass="153712" checksum="3667CC46BAA0FB62" modified="2025-10-08" version="1">MAGSDSSKGSPPGSSTSRLAIKAESEAPSVSESQASTGAEVASVQTPSVDEEFRSPTQQTAPFLAKSNESTASTTINPSISQDIPFAPLSDALGPSVTAHNEGSQHSIGSPPAPHTVTDVETTDDDQSQDGGPDDDDNDNEEDEDEEDNSDEQSTEEESEDSDEEEEPQLKTARLTTNLGPIYRNGDATSAFLVGGDKMIVGTHNGNIHVLQLPIFQNVRVYHAHSASVTAISVSPFPPPIFSQPNAESGSFASAVPSTLIEPLRRANSIASTHTSSTLPPSANARSPAPVPNIPSNNIYIATSSTDGNVCIQSLIDPKDVQLRNFARPVQAVALSPDYRNDRTYLSGGLAGNLIVTIGGSPGRSTSTTIGTAAATASGWLGSIGLGSGSGKDTILHSGEGPISTIKWSLSGKYVAWLNEFGIKIMRSRLHLDAADAPEDAWKRIGHIDRPQTEEWDTMASVWKGRAEWIDEKSIEIETATLNSLNRADTSSSSKSTSMLQSKTIERLVVGWGGTIWIIHVHPGAIGVGKHVGERIPGRAEIANVLRMDCIISGFSFFSTNLLLVLAFCQPKNDDEDEYRDGHDNTDGQNTPKTRLRSGSEPSGGKKRRQNNKPPELRLIDLDTQFEVDKVSLILSRYERLSCNDYCLGVLPAMEEPVGGAAKGALETIAGLGTDMWNAATNPMALFSSAASVATRDSNDDKTSRISSTTSGILTSMGSPTSNGPGILNPNMAKPGMKIFIHSPYDCILAMKRDLGDRLEWLLGQKEYRQAWELLDSHPEILDTPFSQSSLASASDESHMPDDNSSVTATSSAKSPYSPTEKEKRRVGELWIRSIVESGCWREAGEVCSRVLTTSDRWEKWVWTFAGAHKFDEIVHHIPSAPMSPPIPPACYEVILGHYIKTDKPRMRDLLLQWPTELFDISAITTTLENQLKFRDVREDSVEAGEVGRDWRIVVACLARLHEANGRTREALKYHIRLKDADAVFRLIRQGHLAEVVADDIPSFIGLRVEPDFMGEKDLEEATSEAITLLVDEARHGLVKPGVVVKQLMARDLRLYTFFYLRGLWTGTGVCDTDEGGNAIATTNGTADRLVMESKSLVDEFADLAVSLFATHDRNLLLDFLRTSTSYVFEAAVKECEKRSYDDELVFLYSKTGEMKKALFLIIDRLHDVSKAISFAKEQDDPDLWEDLLNYSMDKPRFIRGLLEQVGTALDPIRLVKRIPEGLEIDGLREGLGHMLREHEIMCSISEGVARVLRSEVSAAQKDLRIGQRRGVKFDVASDYSFMSEKANGGAAVAQPLAAKKRDIFGQEIEDDDLNTAHLHPAIEAQPGHCAKCQRAFAEFEEETLIGFVCGHVFHTSHLLEMTQPGRRVDQDLITGMGDNTGGGYLIGSKVTHARLLRGRVRGGCPICH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHC0</accession>
    <name>A0ABR3ZHC0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase Alr4036 family FMN-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001376</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000021">
        <property type="protein sequence ID" value="KAL1899607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024624">
        <property type="entry name" value="Pyridox_Oxase_Alr4036_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28243">
        <property type="entry name" value="AGL049CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28243:SF1">
        <property type="entry name" value="PYRIDOXAMINE 5'-PHOSPHATE OXIDASE ALR4036 FAMILY FMN-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12766">
        <property type="entry name" value="Pyridox_oxase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyridoxamine 5'-phosphate oxidase Alr4036 family FMN-binding" evidence="2">
        <location>
            <begin position="10"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="281" mass="31183" checksum="F75E700B87926D46" modified="2025-10-08" version="1">MPPTSLKSAAPWRAAFHSQISKLSIPAFTISTIHDDPMKTTASPPTMAVGPQPRARTVVFRGFWGELPANPHNPAPRNPQYWQSEVLCITTDVRMAKVVELGGDENGGGGPFEAVFWIPDTMAQWRIRGRGYFLGQDADDNVDKCSLVRDQVQPRMWRASSEEGQECRQGLEESSEMDRATKLWSWAREVTAHFGNLSPMMRGSFRNPAPGTALSSGPGREGLGQGQSVEDLHDALARENFRVVLLVPDEVDYVDLSDSSKAKRWLYTIDGGEWGAQELWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHC7</accession>
    <name>A0ABR3ZHC7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000021">
        <property type="protein sequence ID" value="KAL1899597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="197" mass="22138" checksum="F74C4145AAEAAD6E" modified="2025-10-08" version="1">MTSPANAFNRFQSPPARLGALSGNRKRSRDDDEDEEQQQNDSQMRPRRITGAVGAKRVIMMPTSQSTPTLSSVHQPQTIDELTLHLGIGWRRLSSEEHIRAAARGWARYIEMHYPLSNVTITLESKALQSYLVESNEGFFLFSEDLRQGRLVSRTREGVLANLKTNPPVFDSSSYPMSASETSRIQTPVQQNGMQVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIF5</accession>
    <name>A0ABR3ZIF5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial</fullName>
            <shortName evidence="5">Glu-AdT subunit A</shortName>
            <ecNumber evidence="5">6.3.5.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">HER2</name>
        <name evidence="7" type="ORF">Cpir12675_000908</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-glutamyl-tRNA(Gln) + L-glutamine + ATP + H2O = L-glutaminyl-tRNA(Gln) + L-glutamate + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the amidase family. GatA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.7" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00120">
        <property type="entry name" value="GatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004412">
        <property type="entry name" value="GatA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895:SF7">
        <property type="entry name" value="GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT A, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="6">
        <location>
            <begin position="55"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="5">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1900441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="515" mass="55349" checksum="90B0AA02483D2D6C" modified="2025-10-08" version="1">MQSSLRKCHLDKKLLRHCRLGSTLNKLVSETNHWITKRPDSAIDADLKTPGSFRLAIKDNITTGVLSTSCASRILEGYTSPFEATIVAQLRARNGVIVGTTNMDEFGMGSHSVNSAFGPVINGTSTATELRSAGGSSGGSAVAVQVGEADVALGTDTGGSVRLPAAYTGVVGLKPSYGMISRYGVVPYANSLDTVGLLAPQIDPIYRLLFEQGIYLEHDPKDPTSLSVATRQRCAKSHGPPPASLADAMPRHPHKITIGIPLEYNVDELDPRIRATWAAAAEEIETWGARVVPVSLPSTRHALSAYYIIASAEASSNLAKYDGVRYGKDNSSTIDESNNKTLYADTRRAGLGPEVRRRILLGAYSLSSEAMNNYFIQAQRVRRAVQRDFDRVFALLNPLYTTKPFDLSEMGDDVVLDNKLGPPQVDFLLVPTAPTFAPRLDQALTQPSTAAYANDVFTVPASLAGLPAVNVPVKAQGKGTNEGHNVVGLQLIAQFWDDARLLGMAQQLAKIMSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIH4</accession>
    <name>A0ABR3ZIH4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">40S ribosomal protein S17.e.B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPS17B</name>
        <name evidence="4" type="ORF">Cpir12675_001107</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.60.20">
        <property type="entry name" value="Ribosomal protein S17e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00511">
        <property type="entry name" value="Ribosomal_eS17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001210">
        <property type="entry name" value="Ribosomal_eS17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018273">
        <property type="entry name" value="Ribosomal_eS17_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036401">
        <property type="entry name" value="Ribosomal_eS17_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10732">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10732:SF0">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00833">
        <property type="entry name" value="Ribosomal_S17e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116820">
        <property type="entry name" value="Rps17e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00712">
        <property type="entry name" value="RIBOSOMAL_S17E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="147" mass="17079" checksum="E5AD37A1B23C9746" modified="2025-10-08" version="1">MGRVRTKTVKKSSKVIIERYYPRLTLDFETNKRICDEIAIIASKRLRNKIAGYTTHLMKRIQRGPVRGISFKLQEEERERKDQYVPEVSALDFTQNSENGQLDVDVETKDLLKSLGFDSIPVNVIAVSQVQPNERGNRRFGDRPRRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIK1</accession>
    <name>A0ABR3ZIK1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000020">
        <property type="protein sequence ID" value="KAL1899653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="483"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="363"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="494"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="561" mass="61902" checksum="874CAA8264CF0A09" modified="2025-10-08" version="1">MQSQALPITCGEPHCRFRAIIETEDSSHRYCIAHLRAQVGDVRSELLHRRSCAPRFHVPISANVNYRSSHYQYQRQNSTSSAMSYKQSSTTTNADIERDLLLVAECLRRGMRRILPVEDIQMPILPHQVAEPEQQPLQFLNLDSDSEYEDDPEEVFERPVPQSRDSLFPACGPAGDRFETASWSSHSTVEMSSPPPRTYLTLWEVVVDSTMRLWDQPDNLGFDTESNFENAPSHYPEPPKASENLSDHAISQYDPEDDEIALIKEYQSCSRRADSACIMPPTPIHATHPVLEITPPPSTSSVYINGRTWWALYGSVPSFCGSPAFHRAARDAHLDIPSAVATARRWGLVVRPSTPASISPYNSPMHSPRSSFSPSFSCPRTPRDQRPDETNPFRDILADEDLEIFGLSNVLRLVNCGIPTLVLPPGGAFPEAALSGMEQVAMADEVASYMTVHGSGAGLASPTSPSGGSSKLGRYFLAATPSPLVPAPQRAPRSHGESRRRLDAGGFAPDVNPLRLNPVWKDDGSPGESSLPEMFIDKRNLTEAPVINWASAGLISSENMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ42</accession>
    <name>A0ABR3ZJ42_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">L-type lectin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_000867</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051136">
        <property type="entry name" value="Intracellular_Lectin-GPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005052">
        <property type="entry name" value="Lectin_leg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223:SF28">
        <property type="entry name" value="LECTIN, MANNOSE BINDING 1 LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223">
        <property type="entry name" value="VESICULAR MANNOSE-BINDING LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03388">
        <property type="entry name" value="Lectin_leg-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51328">
        <property type="entry name" value="L_LECTIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046972445" description="L-type lectin-like domain-containing protein" evidence="8">
        <location>
            <begin position="21"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="419"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="L-type lectin-like" evidence="9">
        <location>
            <begin position="21"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1900730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="449" mass="50739" checksum="7A93155B55B54B96" modified="2025-10-08" version="1">MRFQISAALAAALLSGFADAQFLLNEFSFGYSGRISVENGRIPGFNVRGQPDDPEILSNRIVLTPLDPGNEKGGIWSDHDLLHSTWVTDVDFRANGPDRGGGNLNIWLVENGPDVIQAESVYSARNFKGLSLTLETQGGIGTVRGFLNDGSKDYSLERNVEALAFGHCRYSYRNLGRPSQIKLRQDAVTFRVEVDGYLCFETDRVRIPAGYRLGVTATTPDVPDSFELFKVVVMSESVTPPIVDQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQFTSEDDNLDGSLPDTDASTIRDALLQFTDLHDRLQVLDHHISTIYHSIKVSKDTANQHNSNLMKVIESFRSDLRTDISRFSAVGELTAKVDSLESELKRSHSEIQTSVRILENQLATQMGRHHSKLTDNLTTVHSNHGRLIWIIICSQIVLVGLYVMYKRKGRMQHVKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ47</accession>
    <name>A0ABR3ZJ47_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">E3 ubiquitin-protein ligase</fullName>
            <ecNumber evidence="9">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">RSP5</name>
        <name evidence="15" type="ORF">Cpir12675_001087</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RSP5/NEDD4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000015">
        <property type="protein sequence ID" value="KAL1900086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd08382">
        <property type="entry name" value="C2_Smurf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024928">
        <property type="entry name" value="E3_ub_ligase_SMURF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050409">
        <property type="entry name" value="E3_ubiq-protein_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254:SF440">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE NEDD-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254">
        <property type="entry name" value="HECT DOMAIN UBIQUITIN-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001569">
        <property type="entry name" value="E3_ub_ligase_SMURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 9 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 9 10" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="C2" evidence="12">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="13">
        <location>
            <begin position="264"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="13">
        <location>
            <begin position="371"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="13">
        <location>
            <begin position="429"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="HECT" evidence="14">
        <location>
            <begin position="518"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="142"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="287"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="365"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="142"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="210"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="304"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="327"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="10">
        <location>
            <position position="820"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR001569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1900086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="852" mass="95240" checksum="972846AFE41810A8" modified="2025-10-08" version="1">MSSRLEPTSQGAMNLRVTVIAADGLYKRDVFRFPDPFCVVTFNGEQTKTTGVCKRTLNPYWNESFDFRVSEDSILAVQVFDQKKFKKKDQGFLGVINVRVGDVISFGADAGDQMITRDLKKAADNLVVNGKIILNLSMNLQNPPNRNNSVNPASAPQNIGSSSRVSLPGSTLSTSTDGRPRSPLPPSQMGAGGPPGPSSNMGPGPKPVNLNHSQSVTASGSGSLLPPAGPASAEAAVKRTGATGAATGIPANTNQMSPFEDAQGRLPSGWERREDNLGRTYYVDHNTRSTSWNRPNANGVVAQSDRDATTQVERQRHQNRTLPEDTGANSPTLQAQQAGSSAGTPPPNIAAAAAAAAGNVLMSGTTQAGSGELPSGWEERRTPEGRQYYVDHNTRTTTWVDPRRQQYIRVYNPQSNGSGVQQQPVSQLGPLPSGWEMRLTNTARVYFVDHNTKTTTWDDPRLPSSLDQNVPQYKRDFRRKLIYFRSQPAMRITSGQCHIKIRRSHIFEDSFAEIQRQTPADLKKRLMIKFDGEDGLDYGGLSREFFFLLSHEMFNPFYCLFEYSAHDNYTLQINPHSGINPEHLNYFRFIGRVVGLAIFHRRFLDAFFIGALYKMILNKAVALADMEGVDADFHRSLQWILDNDISDGILEQTFSTEDERFGTIVVEDLVPDGRNIDVTNENKKEYVDLMVKWRIQKRIEEQFKAFKEGFSELIPQDLINVFDERELELLIGGIAEIDVDDWKKHTDYRGYTENDEVIQFFWQTIRGWDGEQKSRLLQFATGTSRIPVNGFKDLQGSDGPRRFTIEKAGDINNLPKAHTCFNRLDLPPYKSLEMLQQKLTIAVEETMGFGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ84</accession>
    <name>A0ABR3ZJ84_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000782</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046271655" evidence="2">
        <location>
            <begin position="21"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="353"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="435" mass="43793" checksum="44954E065A36DD50" modified="2025-10-08" version="1">MTILRNVMLGLAVGAANVMAADCAPDACSEAVAGAGLACGDFLKPSYNSTPVVPEALAYVCDVAAVSSACLCATSTAPVPTTSLPYYPPTLSATTTHSAPVVQSSPSGGWPISHPPYITVYTTTSTVCNTEVHTITSCGPEVQHCPAESTVVVTSTIPIYTTVCPVTETVTPTTWGPKPTTWSPPANTTWYPPANTTWSPPAETTKLITSTIYSTHVYTKTACPPEVKDCPAHSKTVTTEIIPIKTTVCPPEVPTPEVPPPPPVGSTTIVVPTHNGTIPTYVKPPVQPTSIAPPSPPSPPPSPPSPPSPPSPPSPPSPPSPPSPPSPPSPPHENTFSTVVVSTPGAVPPVEIPPAETTPVAVPPVETAPGAVPPPAGNTPSVPAANTPVPAGSSPAVITTAAATTGPLTVATAGGVSIKSSVIAMALPLLVAALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJA0</accession>
    <name>A0ABR3ZJA0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_001383</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000021">
        <property type="protein sequence ID" value="KAL1899614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45969:SF69">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12190)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45969">
        <property type="entry name" value="RING ZINC FINGER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="243"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="17"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="289"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="353"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="443"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="526"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="645"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="17"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="35"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="316"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="328"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="369"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="455"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="563"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="583"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="670"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1899614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="713" mass="79458" checksum="DDF684C1AA7B982A" modified="2025-10-08" version="1">MRILSDLAGMISLPTTNFGPIQDAHQNPIAQGQTRSHEQYPDSDAAHRRPEPAPQNESAHDRNQNHQNGGVRETEAASESGHQNWDSQHQEESDDRLRTFEANINRAIPLSLPRNLINNDMTALNEQPTWFEQFIHTRNQRTFRAFSANLDNSEETENLATGSAIHAYISVRELFSLIGTGPRGIYGDAVYSQEGLDRVITQLMAAESRTQGIRPTSEAALAKLERLKADDAFIENHKKSLECTICLDQTKLGDDVIFMPCKHWFHDECLCSWLKEHNTCPMCRSTLEAAPHARRPSSTSFSRLDGSNALREENANDATETAANTDTRSTTPSADSDGNTMMRRLLFPLFGGSAGAGAGDAPDRPRAQAESNGEASAASVAASFENSENSERASNRHTMEDPLRAFMRSFEVQMQQIQPFSTSNELNRDASWESTDQRAAPLRQILQPTAQNNNDSREATSSRTEENQDRSETERQPQTHMHTFTTRVPLLHVPPQAAMGMIGHLLSGATDSMAAAGFGTHVFVLPRPRRQTSEDALSTSRDHRPGAPDEIGTSGASGASGATESNINGRGQNDPQWTTALRMEADETRQRDRERQRELRRRQDGEVDQDRTGSRREATTNRSTGLASILGFALGDSRLNTHSHIQERGSQHGVSQRSREEQNLNQQNENQRDRNQRVHNQNRRDQGQSNANESRWPWFRRLSSRRSGNGGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKD1</accession>
    <name>A0ABR3ZKD1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA-guanosine(34) queuine transglycosylase</fullName>
            <ecNumber evidence="6">2.4.2.64</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_001109</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.64" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="entry name" value="Queuine tRNA-ribosyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004803">
        <property type="entry name" value="TGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00430">
        <property type="entry name" value="Q_tRNA_tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00449">
        <property type="entry name" value="tgt_general"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43530">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE CATALYTIC SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43530:SF1">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE CATALYTIC SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="tRNA-guanine transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-guanine(15) transglycosylase-like" evidence="7">
        <location>
            <begin position="1"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="367" mass="40474" checksum="C4F896A45DFFA7B1" modified="2025-10-08" version="1">MPVATQASLKGITPEQLEETGCKLCLNNTYHLGLKPGQEVLDKVGGAHKLQGWNYNILTDSGGFQMVSLLKLAKVTEEGVRFLSPHDGSPMLLTPEHSMSLQNSIGSDIMMQLDDVIVTTSNDQARMREAMERSVRWLDRCIAAHKNTSTQNLFCIIQGGLDIEMRKECCREMLARDTPGIAIGGLSGGEAKEDYCKVVATCTALLPELKPRYVMGIGYPEDLVVSVALGADMFDCVWPTRTARFGNAITKHGILKLKISKFMNDFSPIEEGCICPCCRPKSEGGLGITRASIHHIASKETAAAHLLTIHNVHYQLNLMAEIRQSIIDDCFPAFIRKFFSDLYGGNKSKYPSWAVNALFEVNVDLMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKQ1</accession>
    <name>A0ABR3ZKQ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidyl-tRNA hydrolase</fullName>
            <ecNumber evidence="1">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_000871</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the PTH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1470">
        <property type="entry name" value="Peptidyl-tRNA hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001328">
        <property type="entry name" value="Pept_tRNA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018171">
        <property type="entry name" value="Pept_tRNA_hydro_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036416">
        <property type="entry name" value="Pept_tRNA_hydro_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00447">
        <property type="entry name" value="pth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17224">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17224:SF1">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01195">
        <property type="entry name" value="Pept_tRNA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53178">
        <property type="entry name" value="Peptidyl-tRNA hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01196">
        <property type="entry name" value="PEPT_TRNA_HYDROL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1900734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="210" mass="23633" checksum="D34118B6D97A0AD7" modified="2025-10-08" version="1">MIEKVLVVSLGNPKPYLETFHSAGHLAIQSVQRLIPGQPMWSSQRIGKQKAQVSMGQKFLLIQSPTLMNVSGGWMAKTFKEVVGTETNKVGFVVLHDDLEGGLGDVRIRSWKSSHRGHNGLKSINSYLRKEEFPNSYWARIAIGIGRPEKRTSDAVSRYVLRPLQQNEKQALNEEAPPQVIQLLKDLEEKWAREVKRNAPSIVKISAPQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLD6</accession>
    <name>A0ABR3ZLD6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Eukaryotic translation initiation factor 3 subunit I</fullName>
            <shortName evidence="7">eIF3i</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Eukaryotic translation initiation factor 3 39 kDa subunit homolog</fullName>
            <shortName evidence="7">eIF-3 39 kDa subunit homolog</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">TIF34</name>
        <name evidence="9" type="ORF">Cpir12675_000405</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat STRAP family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the eIF-3 subunit I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03008">
        <property type="entry name" value="eIF3i"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027525">
        <property type="entry name" value="eIF3i"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19877">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19877:SF1">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24805">
        <property type="entry name" value="EIF3I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 9" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="6"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="48"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="284"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="339" mass="37934" checksum="C1CD901577149265" modified="2025-10-08" version="1">MRPILLSGHERALSQVRYNRDGDLVFSTSKDQQICVWYSHNGERLGTYNGHVGAIWTVDVDPTSTMIASGSADNTIRLWNIKTGKELKCWEFPTAVKRVEFNEDGTKLLGVTEKRMGYLSNIIVFDINPDPEAPQTDERALTIVCDNSKATVAGWSYLSKYIIAGHEDGSVSQYDSKTGDLLENFPIHELNANITDLQWSPDRTYFVTASKDKTAKLISAKDLTVLKTYVSDTPLNSATLTYNKDFVILGGGQAAADVTTTSARQGKFEARFYHKIFEDEIGRVRGHFGPLNTVAADPTGKSYASGGEDGYVRIHHFDKGYFDFMYEVERERKNKIQKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLH3</accession>
    <name>A0ABR3ZLH3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="413"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="469"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="668"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="436"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="472"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="490"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="535"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="704" mass="77010" checksum="02E473C322C69AB9" modified="2025-10-08" version="1">MVPPFVSTSTNSPHDRMEGPLMVPPDRGQILGRAAWKTRYVVCGKRESSASGPQTPSSSKARQPLRITSDEVYLSLYKNKGDSDSVYQCAVSHITDCQVQMIAHRKQGPVLPTLVITVSDRERKRRSSRAANLIGGNKESFSSALTLWLRTTPEDKQSLLHEWGRFIMARKLPMSPDSPASPTFMNPFGARNEVARPPTGNASGRVPMHHKSSIATQSSRERAVTYSSDSPSLRSKASDLSTPSSTMPAYTISNSYSQGQCQVFSPAASDLPSPATTTTLDEYRNDSGESWPVPKGPATNTSSPIRRRESLDKRPSAVDSSSPPVPGETILDRAFNMRMVPGSERMIPGEEKLSSLARFEALMREADVKRRDEEHRRQVEEEMAMRSTFNSDFMDEDKDFDEMAVFHNHHDDTRHQGMHEQQPLQSHWSASPVNVTSSAPTTATPSQRHTLISPAAQRALNFITSRHESGGLVNSSTSPSLGQHSGSASHRPRTGYSGRRRPTISSRTHSQPHSFFQQNIVSEAPPLGPSAIPKQPSTKSRPQTTIADRRQSETRINYRSSKSVVTIMKNCSSGSGNYAASTATKPKMGLTGATAVTAPTSPNISASASADIMQARRSSFTECDKRISQASSMLIMQSNATGTSISDGRASTDTYDLPFDENLVPQQNRHTLVPPPRPSRNWASTATDRGGFRQGMVSTEGGFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLT4</accession>
    <name>A0ABR3ZLT4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">FAL1</name>
        <name evidence="12" type="ORF">Cpir12675_000311</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18045">
        <property type="entry name" value="DEADc_EIF4AIII_DDX48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="11">
        <location>
            <begin position="29"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="60"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="241"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="7">
        <location>
            <begin position="29"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1901621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="403" mass="45891" checksum="89953CD64E3F0C8D" modified="2025-10-08" version="1">MTDGNSAGIDRKADERMEFTTSKEVTVHPTFEAMSLKENLLRGVYAYGYESPSAVQSRAIVQICKGRDTIAQAQSGTGKTATFSISMLQVIDTAVRETQALVLSPTRELATQIQSVVMALGDYMNVQCHACIGGTNVGEDIRKLDYGQHIVSGTPGRVADMIRRRHLRTRNIKMLVLDEADELLNRGFREQIYDVYRYLPPATQVVVVSATLPYDVLDMTTKFMTDPVRILVKRDELTLEGLKQYFIAVEKEDWKFDTLCDLYDTLTITQAVIFCNTRRKVDWLTDKMRENNFTVSSMHGEMPQKERDSIMNEFRRGDSRVLISTDVWARGIDVQQVSLVINYDLPSNRENYIHRIGRSGRFGRKGVAINFVTTEDVRILRDIEMYYSTQIDEMPMNVADLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM00</accession>
    <name>A0ABR3ZM00_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000578</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046147888" evidence="2">
        <location>
            <begin position="21"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="315" mass="36185" checksum="8A4E8543D1DD9A29" modified="2025-10-08" version="1">MKSPFSFLSTFLSFFGLHQTNLIEDHGYQLKTIDHLHMIRSSHLYYGREYVNAIGFTPEAKAATIYIANNDQEPMHEDKLSLSEIYNTLCENEGLEPENMKWITFDVNDDPETDGIISIIHKKRGIDRLNEVVILPDDMEWDLIVRTEYYQLMEMVTAQSPQKILLRHYSYVSSSDWELVLFTNCIYFSFESPEDTISTGQSGWPFDDEDQREAVFFEEQDNEFSDDSDDSDDFESSDAFVDHEDFGGSESSDTTVGHEGYKTVKGSDVGEVDQVDQGSEIDQGSRDFEDSENDDETNSRWFSLKPESPLAHPQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM68</accession>
    <name>A0ABR3ZM68_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Metalloendopeptidase</fullName>
            <ecNumber evidence="9">3.4.24.37</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PRD1</name>
        <name evidence="9" type="ORF">Cpir12675_000629</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase M3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.37" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000008">
        <property type="protein sequence ID" value="KAL1901140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06455">
        <property type="entry name" value="M3A_TOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.40">
        <property type="entry name" value="Endopeptidase. Chain P, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.10">
        <property type="entry name" value="Neurolysin, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024077">
        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024080">
        <property type="entry name" value="Neurolysin/TOP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804:SF84">
        <property type="entry name" value="SACCHAROLYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M3A/M3B catalytic" evidence="8">
        <location>
            <begin position="222"/>
            <end position="722"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="726" mass="82322" checksum="846F8873C331E0A2" modified="2025-10-08" version="1">MIPPQHQKPPQAPPLFTGTKESIISDSKAMCAATRGLLDKLVSEISLDDANFNNTIVPQIHDENKASNGHILGFYQYVSPNAELRTASTEAEALLDDFAIEMGMREDVFKLVDAVYSRRETENLDGESLRFIEKERKAYIKNGLSLPAGAVRDRFKEIKKRLSTLGIEFNKRLTEENGGVWLTTEELDGVPKNVVDNLEKGAGDNEGKLKLTFKYTDIFPSLKFATNPETRRRIFVANENKCNDNVALFKETISLRDEAARKLGYPDHATLVIEDKMTKTPKLVHEFLGDLRSRLADGGRKEIDHLLELKKQDMESRGIQFDNKYFLWDHRYYDRLMIEKEYSIDENLIAEYFPLQSTIAGMLKIFEELMGFSFHELDATERSRLSPTDNGKDISWHEDVIIFSVWNDASEGDGFVGYLYLDLHPRAGKYGHAANFNLQPGFVREDGSRQYPATALVCNFSKPTATRPSLLKHDEVVTLFHELGHGIHDLAGHVKYSRFHGTNTVGDFVEAPSQMLENWCWTPEVLKRLSKHVETGEPIPEDLIKKLISTKHVNGALANLRQLHFGIFDMAVHTPKSHADIEKLDTSKTYNELRASICHLLGPDSLGENRYENPLVSHYITEISNESLLTDYDINSDWGHGEATFGHLMGGYDAGYYGYLSSQVYSTDMFHSVFKNDPMNAAEGRRYRHTVLEKGGSQDEMKTLEQFLGRKPNSEAFYRELGIPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMP7</accession>
    <name>A0ABR3ZMP7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_000376</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052360">
        <property type="entry name" value="Transcr_Regulatory_Proteins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206:SF13">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATORY PROTEIN MOC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="220"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="25"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="259"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="437"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="34"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="79"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="278"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="329"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="383"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="444"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="496" mass="53315" checksum="99C26D94DBEBF702" modified="2025-10-08" version="1">MAPLPPSTSAVYTTSAYSTHPQTAVSPYLPYQSGLPQTHNGSQPPSQQSYGAPAPSHHQQHQHQRIETTQAQSASPSMAHLSSQQHHQALPQHHQSHHMSQRPPVTYSMSAPYQPPINAYAFTSAVSHDNYRRADPTSGGLPSMRTLDHSGLPAAPMGHTPGMMLMGSHHEMGYYNPAHGMIGNPYGMSPDILGRYSMTHDPRFMPRNPKKEIKRRTKTGCMTCRKRRIKCDETHPTCNNCKKSKRECLGYDPIFKQQAQGQPAPHLHNGQSQPQQPSSIKNMSSPSSEHSQQLSQPQLPSPLAQHQPQSQASSQQGQQPHSRPSSQASPLSMPRSLSSSVAPSVSNSMASSGVQSSSNGPLFGHQVQSQHHSQSHHQLAGIPSTQSMSYKNTPSMCVSSSYSTPNSTVVNSSGYDTQSPTTAYDYSASIDPALQSGAGTNGSVNGGGNHVSHGGSGVGSNMGAQPRPGLGMSMYSSSEHIPQPRMVEHLPHIPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMT1</accession>
    <name>A0ABR3ZMT1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="15">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Cpir12675_000642</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="15"/>
    <dbReference type="EMBL" id="JAWDJO010000008">
        <property type="protein sequence ID" value="KAL1901153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF10">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 17" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046617668" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="17">
        <location>
            <begin position="24"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="18">
        <location>
            <begin position="22"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="263"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="266"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="320"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="338"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1901153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="376" mass="38880" checksum="717DCE43CAD81259" modified="2025-10-08" version="1">MPSFTSSIAAAALLSASAVSAHGHVKNIVVDSAFYQGWDFEKGMGYNNNFPDIVGWSNTALDNGFVAREAYATPDIICHLNGNASAAYASVAAGGTVQLDWNAWPDSHKGPILDYMAACPESGCTTEGKTALEWFKVSEVGLIDNSMNSGYWASDLLIKNGNSWQVQIPSSLAPGIYVLRHEIIALHGAGTPQNYPQCVTLKVTGTGSDKPSGITGDKLYTSSDPIWDFSLYTGATSYAIPGPAMMPGANPILEQKSVAPASTIEPTPYGAGGADAAAPTYGSNPTSATTPAAAPTTPPTTPSVSTPAYQAPADTSTTGAVSTPAANVPVVPNTPASQPTSSQPTYGSQPAATPAAAPKTCSKKRRRSHARDVHNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN11</accession>
    <name>A0ABR3ZN11_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000594</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="76"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="463"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="131"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="480"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="489" mass="54893" checksum="AE71D36089EF0B0D" modified="2025-10-08" version="1">MGSSSTNPLSLGAEGIILSTTSTPNAVNANIEHYLKMAKNSKVRKTRGTAAAKVALDDDYESSENGFLSGADLIEKWDCGPENEPSPSEREDEVGYGNSGHDSSTSKMDVGEQYNNFNSTVGIFPLCDHPKRSDKKAYDEAQARRRALENVRDIWQDELNCLVEKRDKGQYMKNYIREQRLQGILYHDQTAATRFTVSDIFNIPDSKRSEPPPPGTKNHYRTLQDAIKAMKWEVPVSEHYMMESKLRTRHQTCGGTLSQKGPARVLADHVASVLEHMRVNKLDRPDLSRLKDKSEFLITKYCIENNELPPAVTSFCNTWGLSDMMMVVRGARSIYDTESTIFLRHLNASPDGQRFLASHTSNREGVPSDLVDNAPLVYMNSKRPWPIDQMPRDQESYKAVLTLESQNIEAIMDPKTASDMAHEAIQLRKLGPCPYDAQAITDTGGLLPSTEHRDEVLKDKRVEAKWSGRAGPQVKKSRVSRVESEEIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNP7</accession>
    <name>A0ABR3ZNP7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">37S ribosomal protein S22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RSM22</name>
        <name evidence="9" type="ORF">Cpir12675_000296</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Mitochondrial ribosome (mitoribosome) assembly factor. Binds at the interface of the head and body domains of the mitochondrial small ribosomal subunit (mt-SSU), occluding the mRNA channel and preventing compaction of the head domain towards the body. Probable inactive methyltransferase: retains the characteristic folding and ability to bind S-adenosyl-L-methionine, but it probably lost its methyltransferase activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052571">
        <property type="entry name" value="Mt_RNA_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015324">
        <property type="entry name" value="Ribosomal_Rsm22-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13184">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN S22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13184:SF5">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 17, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09243">
        <property type="entry name" value="Rsm22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="224"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="739"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="819"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="224"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="249"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00045681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="851" mass="95707" checksum="A4D30E3FFBA54EAA" modified="2025-10-08" version="1">MLSAQRAAPQRQLTAFCTISRSGLLIRPCTTKHPIVALHLHPHAQSTQITRSFSYTLQQKNDNRTPSLSSAKTEKVEAVAASGKDVEKTVRDAKQRFRDTLPKGYLKPDEYELYVRLYGPPLRETTPDDVGIPSHDNYEALDAPIPGPYEMYNTQATEVREDGHQQSYPAERHEDRKHESNYVEIVARNQREYDALKKLELDFKAAKELADKEAAEIKIQETEERIAEEQRSSEEVDEEGAAQETEERHEDEEWDCELPDPLANSRLHPLTQDARFGISPSTVYLPADRLVSHTTDILKRIAPSHIKLAAERLFGGPGLPHGPVTPQRMKTVEMKAIPIQMQHRRMQPIDADAVMAAYVPPVYASILGVLVELRKRLGSSWIRGLMEKNGDEGPRVLDVGGAGAGIIAWEQILGTEWQVLHEKGEVPKDSRPITRKSVVAGSEALRDRLSKFMYNTSFLPRMPDYVHSAENADRVLDGPEKPQTRKRYDVVLASHQLLHVEEGHKRRAVVNQLWSLLNPDGGVLVIIEKAHPRGFEAVADARQRFISEFLQTPGAKPQEEDISDSFTRIKEPGMVVAPCTNQRRCPLYLVEGKSLGRKDFCFFAQRYIRPPYLQRIMQAKHRNSDDVEFSYVAIQRGTMGPPGLEQNAKSAGRAFTGYEKDATDYHALALPRNIRPPLKKHGHVSMDLCTPEGNFERWTVSKSFSKTAYHDARKIRWGDLWALGAKTRTENRVRMGRGDVVKDGGVKGHQARADETRSSSKRPEVVNLQMNALGKAVPMQKPMKGYHHTKGGRHMAKAQASKGIREVERELDRVLHDGAVKADMSKQKEEAAVEQGVQKEHGARGSGDHGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNS3</accession>
    <name>A0ABR3ZNS3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TUG ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000217</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16105">
        <property type="entry name" value="Ubl_ASPSCR1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021569">
        <property type="entry name" value="TUG-UBL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46467">
        <property type="entry name" value="TETHER CONTAINING UBX DOMAIN FOR GLUT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46467:SF1">
        <property type="entry name" value="TETHER CONTAINING UBX DOMAIN FOR GLUT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11470">
        <property type="entry name" value="TUG-UBL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TUG ubiquitin-like" evidence="2">
        <location>
            <begin position="10"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="437"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="489" mass="53773" checksum="2BF72BB15AD2B1A8" modified="2025-10-08" version="1">MSSHVWVLGSDLKRTQVKVTPSTYLSDVLAEACKKFKISSDKYQLRHNQKLVDLSLPFRQSKLTSGAKLDLVVKPKTPSIVSVAIQLPHPESTQIPAGRIISKFPSSFTLWQVLRQVESRPANQGRTLRITDRATPISSTSGAGQLYYEMPALNIMGREFTTFADFQKTLSQLGYNSGSVLMRLSFKVTDQPLFSAIEEINAYFKDAEEKTDETTKYEQNGSQSSVPSPEDKDISRADTLKSTIPIKPESVESDTVPKSEAKGPDIQNLPADPLQPVGIFSAPTTSTPAAVLMPVEDTDFIPTIAHAQIHQAQLMLQSQNKRLLSDLELEQKAAERAAKLADTSTVATKVRFPDNSSAQWNWGPNATGSMLHAAVRKQMANPSLAFRLVMVPGRTAILDDQNSLIKGYKLVGGVVVTLLWDESVPKDARTKRFLTPEASQQAQKIVVPQPKELPESGLDNEKPTIVQAPKKESSGGNKVPKWFKLPGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP25</accession>
    <name>A0ABR3ZP25_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dynactin subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_000114</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the dynactin subunits 5/6 family. Dynactin subunit 5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03359">
        <property type="entry name" value="LbH_Dynactin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047125">
        <property type="entry name" value="DCTN5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46126">
        <property type="entry name" value="DYNACTIN SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46126:SF1">
        <property type="entry name" value="DYNACTIN SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21711">
        <property type="entry name" value="DCTN5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00034706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1902214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="196" mass="20915" checksum="6C6F708E891ECB82" modified="2025-10-08" version="1">MSRRPVKGEYIETDTGNKVARKATLVGTQNIMLGGKTVIQPEVMIRGDLARFPANAVPQGQGQSGNNTAIAIGRYCFLSRGCLLRPPARLNKGVFSYVPLRLGDHVFVGQGSVIEAAVVGSHVHIGNNVVIGTLAIIKDYVKILDGAVIPPHMVVSSFSIVAGQPARVVGEIPEGSHDDFELRDLYKTVGNAPQPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPR7</accession>
    <name>A0ABR3ZPR7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000047</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="160" mass="18164" checksum="D2E214F5E9D46F44" modified="2025-10-08" version="1">MCGSFGSYSSMGASAWEPINISSSSSSTSRTDDANSCAYPSWPRRDSLSSNEHTIPNSFLSDDDLFLLSDSDDLRSESSFGSGSPAEDDNTLVMSPNNRFLECQREREVLYAEQQYQRQQQRIQQREMIKMVQLEKERRKAAAKKTRRTKKNVKLTSISE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ18</accession>
    <name>A0ABR3ZQ18_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000479</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047287644" evidence="2">
        <location>
            <begin position="20"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="243"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="273"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="351" mass="35563" checksum="39327ADADC8829F6" modified="2025-10-08" version="1">MHSSIISIAALALAASVSAVDTSVTDGPGGYPTDVPSGFPTDLPSGFPTNLPSGFPTDLPSGFPTDLPSGFSTGRPHGTGRHPRPSGYTYHGHRGTGYKSSAGSYETPAVEKRQGNDEYEAPTGTEESGAYPTEAPSGFPTDLASGSGFPGAYATGTGRGSGRGRGRGRGRFGKGTGIPSGFPTGFPTDMPSGFPTDMPSGFPTDAGEYGAQPTENGEESQDDEYAQPTEVPTTLMKVRRQATSYGSSSPTGTGKGGFLSNLKGFLPSGLGAGLPTELPGGLPTELPGGLPTELPSGLPIDLPSGLPTELPSGLPTELPSGFPADLLSGFLTKLPSGLPTEDSDDDSTPAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YBJ2</accession>
    <name>A0ABR3YBJ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Retrotransposon gag domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_007007</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000543">
        <property type="protein sequence ID" value="KAL1884824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005162">
        <property type="entry name" value="Retrotrans_gag_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03732">
        <property type="entry name" value="Retrotrans_gag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Retrotransposon gag" evidence="2">
        <location>
            <begin position="80"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1884824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="233" mass="26332" checksum="F435E85F6A669092" modified="2025-10-08" version="1" fragment="single">TVTPVYTPAPPRFQGFPQFDGNKGTYRIWKRQMSAMLLLHEYTDVTRVVAAMQVALMGEANESAGGEIQRLAEKAGSTVAEVWKVLDDHFEDPLFRARTSERLENLEQRNKTLDRYIFEYRDLLQQAGGGGYPEVVKIRGLMRGLNDALYERMVTIPMSSTLTSQIESLRGVSQRMEEVTQRKSRKRKPTLFTQPVKIDEGDPMDIDVNVSQVRGEPQRPVRESGTGLPADNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YBV7</accession>
    <name>A0ABR3YBV7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_006994</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000515">
        <property type="protein sequence ID" value="KAL1885337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF458">
        <property type="entry name" value="SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="248"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="293"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="322"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="352"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="394"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="438"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="504"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="529"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="562"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="10">
        <location>
            <begin position="166"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1885337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="594" mass="64178" checksum="10C50EE43C8169FC" modified="2025-10-08" version="1" fragment="single">MSGSRLKFSRNRHRNLLAGHGSTNPDSTPDADAEERGLLDAQYSDDDGEGDRLVLNIARTRIPQLVATQPDSESPKTPRSARSVRFDLTPTYAEAPHTHFLIDDAGRKSEEAINSRRPSSVFDRPDIPFFFDNDGPDSDGRRRGHEMQMADNAVAQWAENERSRPKSSLTSAFMNMANSIIGAGIIGQPYAFKQAGLLAGVFLLIVLTIAVDWTIRLVVINAKLSGTSSFQSTVQYCFGRRGMLAISLAQWAFAFGGMVAFAIVVGDSIPVVFRAIWPDLNNMGAFSLLGNRRVVITVFVLGLSYPLTLYRDIAKLAKASTFALISMLIIIMTVLIQSLRVPADHRGSMTPALWTINSGVTQAIGVISFAFVCHHNSLLIYGSLRTPTIDRFSTVTHLSTGVSMIACMTMALSGFLTFGDKTAGNVLNNFPADNTMVTFARLCFGLNMLTTLPLEAFVCREVMVEYFFSNTSPPPVTSSLDPDDDSAEDRPFVAEGTVPQIGTVLHVLISTALVVAALGVSLATCDLGAIFELVGATSACALAYILPPLCYIKLTTKSWRTYVAMGVAAFGSLVMVITVVQALTKIITGGNETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YF10</accession>
    <name>A0ABR3YF10_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mitochondrial dicarboxylate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">DIC1</name>
        <name evidence="11" type="ORF">Cpir12675_006919</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000425">
        <property type="protein sequence ID" value="KAL1886024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="32"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="113"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="213"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1886024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="306" mass="33709" checksum="92DEF68A7D72A80E" modified="2025-10-08" version="1">MEATKAAAPAASVAKPSLKIQKKEVKSSPAKYPFWFGGSASSMAACVRLQMRTADAPKTMYGTFKNIIKHNGALGVYSGLSASLLRQMTYSTVRFGVYEELKTRFTSADGKPPSFGMLVVLSSLAGFFGGISGNVADVLNVRMQHDTALPPDQRRNYKHALDGMARMAREEGIKSWFRGVWPNSTRAIFMTSSQLASYDIFKTLLLNYTPMGDTLSTHFSASFLAGVVAATVTSPVDVIKTRVMSSTADHSITHLFRDLYRTDGLRWMFKGWTPSFLRLGPQTICTFLFLEGHRSVYRKLAGLPEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFN7</accession>
    <name>A0ABR3YFN7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tr-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_006798</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000378">
        <property type="protein sequence ID" value="KAL1886968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01883">
        <property type="entry name" value="EF1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16267">
        <property type="entry name" value="HBS1-like_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="5">
        <location>
            <begin position="475"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="267"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="320"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="425"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="346"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="426"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1886968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="884" mass="96168" checksum="1F5F5E1E941FB342" modified="2025-10-08" version="1">MAKYDYDEDDVYDSYDGYDENLQYTQDPDSLVYNENGLMIDGGDSIVQEIRAELGSRSDEVTDDQIQKALSLHSADVEKTVQYLFCEVLDPEITDTACSNIMEALGDDSKYTTRTKVKSSLYYYYYDENKTFDYISRGIKTAKATEMKREAEGTSTNEFFFVVQEVLPSSLGYANLSGTCYSESVLVAQQKKQDIEALFSDMPWLSVPLGRQSIFIPPVSVGPVGLLGGSSKLKALAAQRKKQAPVTPLGKSTASMATTCATTTTTTSIATGAAPEKPTPGDLQTASAQDRGSAGQGAYANSTTLLEKSTRPALKRIYNKTAVDKTAPPSHGKDPLESAPGCYGQDEQTSTRNASVTSHVSNGSATVSATQPSAFAQTLFKLSPSSVNTVPQEYPMPYTASSDYAADAFIKPSPDDVVLTAQAQARKFESRKSAPDDASSTSEKPAKTAKPSFNKPNHKNIDVIAEYEHRTTYEKNRLNFVVTGHVDAGKSTLMGRLLLDLKEVDESLINRFRHEATAMGKQSFALAWVMDQNVEERERGVTVDVTAHSFQTEKAQYTILDAPGHQAFVHNAIHGISQADFSILVLDGNTGAFEKGLKGSTYEHILLLRSLGIQRIVVAINKLDMVSWSQDRYDEIKEQISAFLYKFNFSAKNLQFVPISGLSGDNVVTRPKASGLDWYDGPTLVEALDNTKPLPRALNQPMRMMVSDLFSTGSGKLTVSGRLEVGTVQVGDKLMITSSNEACYVQSLLVGRESRDWAVAGENADLVIVGVEATSVSSGDVLSAFDTPLQPKKDIILKTLAFQPLYPLTIDVHRGCLQCPGQINNVMAILDKNNGFITNARATRVETGEFARISVTINQELPVEAGQRVVIRSGGHTIAAGVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFQ0</accession>
    <name>A0ABR3YFQ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Arginine biosynthesis bifunctional protein ArgJ, mitochondrial</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="9">Glutamate N-acetyltransferase</fullName>
                <shortName evidence="9">GAT</shortName>
                <ecNumber evidence="9">2.3.1.35</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="9">Ornithine acetyltransferase</fullName>
                <shortName evidence="9">OATase</shortName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="9">Ornithine transacetylase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="9">Amino-acid acetyltransferase</fullName>
                <ecNumber evidence="9">2.3.1.1</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="9">N-acetylglutamate synthase</fullName>
                <shortName evidence="9">AGS</shortName>
            </alternativeName>
        </domain>
        <component>
            <recommendedName>
                <fullName evidence="9">Arginine biosynthesis bifunctional protein ArgJ alpha chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="9">Arginine biosynthesis bifunctional protein ArgJ beta chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="10" type="primary">ECM42</name>
        <name evidence="10" type="ORF">Cpir12675_006725</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-glutamate + acetyl-CoA = N-acetyl-L-glutamate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24292"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(2)-acetyl-L-ornithine + L-glutamate = N-acetyl-L-glutamate + L-ornithine</text>
            <dbReference type="Rhea" id="RHEA:15349"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
            <dbReference type="EC" id="2.3.1.35"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Amino-acid biosynthesis; L-arginine biosynthesis; L-ornithine and N-acetyl-L-glutamate from L-glutamate and N(2)-acetyl-L-ornithine (cyclic): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="9">The alpha and beta chains are autoproteolytically processed from a single precursor protein within the mitochondrion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the ArgJ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.35" evidence="9"/>
    <dbReference type="EC" id="2.3.1.1" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000359">
        <property type="protein sequence ID" value="KAL1887057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02152">
        <property type="entry name" value="OAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2330.10">
        <property type="entry name" value="arginine biosynthesis bifunctional protein suprefamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.340">
        <property type="entry name" value="ArgJ beta chain, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.70.12">
        <property type="entry name" value="L-amino peptidase D-ALA esterase/amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01106">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002813">
        <property type="entry name" value="Arg_biosynth_ArgJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016117">
        <property type="entry name" value="ArgJ-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042195">
        <property type="entry name" value="ArgJ_beta_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00120">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003802">
        <property type="entry name" value="PRK05388.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23100">
        <property type="entry name" value="ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23100:SF0">
        <property type="entry name" value="ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01960">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56266">
        <property type="entry name" value="DmpA/ArgJ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 9" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="5 9" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="6 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_5044936983" description="Arginine biosynthesis bifunctional protein ArgJ alpha chain" evidence="9">
        <location>
            <begin position="1"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044936984" description="Arginine biosynthesis bifunctional protein ArgJ beta chain" evidence="9">
        <location>
            <begin position="233"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="459"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="464"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole" evidence="9">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <feature type="site" description="Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole" evidence="9">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="9">
        <location>
            <begin position="232"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1887057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="464" mass="48846" checksum="E16876348443B572" modified="2025-10-08" version="1">MLAAARSARFPTTAVASWHQPVRFYSALPGNSIPAAKKKYVPRSGTYPKGFLASGIIVGVKPKNTTKPDLALISSTVPCAAAAVFTKNKFQAAPVTFSRDLLAKKKNEGIHSVLINSGCANAVTGKGGLEDAKLMSETADAVVGGTEGTLVMSTGVIGQRLPITKIVSNISAAHSQLGSDHDHWLAAARAICTTDTFPKLISKTFTLPSAPGIQYSLAGMTKGAGMIHPNMATMLGVMTTDAPVAPNMIKPLLRYAADRSFNSITIDGDTSTNDTVAFLANGAAGGPTVSMLDSVDYLALRDVVTKFSAELAQLIVRDGEGATKFVTIRVVDATSEAAARTVASTIARSPLVKTALYGKDANWGRILCATGYALVSEPGMPETAVDDIVPEKTSVSFVPTDGSAELKLLVNGEPESIDEKRAAEILEAEDLEIRVRLGVGAAEATYWTCDYSHEYITINGDYRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGQ0</accession>
    <name>A0ABR3YGQ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peroxiredoxin 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PRX1</name>
        <name evidence="8" type="ORF">Cpir12675_006588</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peroxiredoxin family. Prx6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000330">
        <property type="protein sequence ID" value="KAL1887324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03016">
        <property type="entry name" value="PRX_1cys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1020.10">
        <property type="entry name" value="Antioxidant, Horf6, Chain A, domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019479">
        <property type="entry name" value="Peroxiredoxin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045020">
        <property type="entry name" value="PRX_1cys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43503">
        <property type="entry name" value="MCG48959-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43503:SF4">
        <property type="entry name" value="PEROXIREDOXIN-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10417">
        <property type="entry name" value="1-cysPrx_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 6" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="4 6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="7">
        <location>
            <begin position="3"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1887324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="221" mass="24644" checksum="B924B03C9DD20AC4" modified="2025-10-08" version="1">MSLRLGYTAPNFEADTTAGRISFHDFIGDNWVVLFSHPEDYTPVCTTELGAFAKLEPEFAKRGAKLIGLSANTLGSHEGWIKDINEVTGANLTFPIIADKERKVALLYDMIDDQDSTNVDEKGVAFTIRSVFIIDPKKTIRTILSYPASTGRNSAEVLRIVDSLQTGDKYRITTPINWVPGDDVIVHPGVKNEEAKTLFPEFRIVKPYLRFTPLPKEKVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHP8</accession>
    <name>A0ABR3YHP8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DUF1740-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_006522</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NRDE2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000314">
        <property type="protein sequence ID" value="KAL1887505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013633">
        <property type="entry name" value="NRDE-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13471:SF0">
        <property type="entry name" value="NUCLEAR EXOSOME REGULATOR NRDE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13471">
        <property type="entry name" value="TETRATRICOPEPTIDE-LIKE HELICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08424">
        <property type="entry name" value="NRDE-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="260"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="40"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="133"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="280"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1122" mass="127506" checksum="C6B50D07B2823EC6" modified="2025-10-08" version="1">MPEQDKKSAVVPKFSSFKSKSSGSPGAEKEKGSRHRSHSNRGDDRSREHHDDRDQGYRRERDRAKHCDRDRESSRDKAYGRDRDQDRHRGKDRHKNHHLDRGRDQSKRRHHHAHRDLSKDRSRSKNSRDLYRSSHSLQGKSSDATSLASSRLAKLPDISNQDFFVIDTKGDPLIHLGLDRYSIPKFGRGHCKFVLGTSMRLFIHRDGPHEQFTLLHPGEYYGPPPLRSKKLAFSMARSLKPSKTSKNMEDTNDVVFMTKKRKRKDLDSSSDEEQPNFRSIEGKAKPKYFSDSESGIDSEADSVPGTQSGIKKRSIELSKRVKANPADIPAWIQLIHLQDDLMREGLAPESEVATGQAHSFTEIKLSMIYKALKASTADADKEALLLLQMREGRKIWPVDVTRKKWIDISSGDYGQRFDLWMAHVDFEITEMQGFHFDTVKKMFTDRLQGIMEKSWRYSPQQSLDLYREAVYVYLRLTRFLQDAGYRELAVAAWQSILELNFFRPVDIENKEHTLAAFADFWESEALRVGEKGALGWSHYLAHDGDIVVPEPKEEDEPGVPTDIALMKEMDIYKLWAANELRSSQKNRLPARTLDDGTGDDPFRVVMASDLEELLVQFPLTVIPDLQEQIIDSFLIFSHIPPRFCSSTWVSRAHKDMFLTPTVPALNEAISQASQKIAKDSKENGWASIQKLLPGVVPSFISSLIRSWNQESVSSAPVDFAWARNVLYQLSTTTTRTPVKGLLSLVMALDWLHDPSVRKSARQIIQSDISNSELYRLYGIFESQNQNKQLSSTVFASAMKLKQDLPSNPPINEVALSWVWTELVDNASHSPALSRLVYLLDGFDINVEVSGTRLLKSRKILADALDLALGLVDVAVFSIVARCSVLLAYLSETEPAQPQNQTQGNISAAMELLWSQFEKLQSRTGQTATQEQLLSFGASLLYLYSSRGPYQRVFLNANLQRCLNWFPQNGFFIELYDYINSTHLLRSDFRNLSQTLLLSHANDCVSNRICVAIHELHHGTIHSAQALLERSISVSSCASASIELWHAYVRLCGQATELQSKACETYYRAVSHCPWSKNLALQAFVALDEEIDVVDLKAVFDTLVNRGLRTHVDLDEYVLQFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHS0</accession>
    <name>A0ABR3YHS0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">UDP-N-acetylglucosamine transferase subunit ALG13</fullName>
            <ecNumber evidence="2 7">2.4.1.141</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 7">Asparagine-linked glycosylation protein 13</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">ALG13</name>
        <name evidence="9" type="ORF">Cpir12675_006455</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 7">Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>an N-acetyl-alpha-D-glucosaminyl-diphospho-di-trans,poly-cis-dolichol + UDP-N-acetyl-alpha-D-glucosamine = an N,N'-diacetylchitobiosyl-diphospho-di-trans,poly-cis-dolichol + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23380"/>
            <dbReference type="Rhea" id="RHEA-COMP:19507"/>
            <dbReference type="Rhea" id="RHEA-COMP:19510"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57269"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58427"/>
            <dbReference type="EC" id="2.4.1.141"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1 7">Heterodimer with ALG14 to form a functional enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the glycosyltransferase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.141" evidence="2 7"/>
    <dbReference type="EMBL" id="JAWDJO010000303">
        <property type="protein sequence ID" value="KAL1887684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004577">
        <property type="term" value="F:N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052474">
        <property type="entry name" value="UDP-GlcNAc_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47043">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE TRANSFERASE SUBUNIT ALG13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47043:SF1">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE TRANSFERASE SUBUNIT ALG13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl transferase family 28 C-terminal" evidence="8">
        <location>
            <begin position="130"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1887684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="245" mass="26514" checksum="7DA907B8D06FE11A" modified="2025-10-08" version="1">MTVFLPVLPTSYHKPPRSRHCFVTVGATATFSGLLSAIQSADFLLQLVLAGFTHLTVQAGRDYEKFLKFSQTVDNTLLTVECFDLKPSLARDMALCRENAGVDKDLDMLLSLNLGTGSGPDAPSPRDLGVVISHAGTGSVLDAMAARAPMVVVPNESLLNNHQLELAQMVEDRKYGVVGTLTTLASDIRRAQSVLIARESRLGEAVICKIPPSEAHSLWGIAQDIVRPTNTICEERESDEVQKEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ26</accession>
    <name>A0ABR3YJ26_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LsmAD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000293">
        <property type="protein sequence ID" value="KAL1887857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="599"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="736"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="875"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="483"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="736"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="880"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="891"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="909"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="934"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="945"/>
            <end position="954"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="954" mass="103030" checksum="99A71356C7B8D7E6" modified="2025-10-08" version="1">MLSTQVIHAFFQQFGLETIEENVLLFMRLQSCLIYLTLNIEAVGAKRDRLTLNKNILMLTSSRRNEFANSSKKSAKSKKLLWPLAGRCKPEIDFPSHPSFALPGAACLIGSHAYEWGHQEFGYPVKKREETKSNFWPDLEVFTHSYYDDPKTIDSVNLTNAPVHAEQQWQRMQQLSSFQRKNTGHLDPSAAEFSQIGQQSHPHKIISTESLPFIFAKVHNMVFNASLSSKLLPGAIGQSSVRPSRNLISLAPLHGARVSRVTNSLGDSNISGAVPPASGNAGVAPKTQSSMINATGVYLSPTGTPVPQTSPYAQGQAPLGNQPYFHPPANQGSANDAAQGFSCSPDNPTFRTHISLKEIENARRSEVGSSQTITMSTKRDSPSSSMIATPQTTVATSECVQVSSSGESTLPSSKLLNHGNSRSHSLSKCSPLASSPPQNRIDVGDPHSTAGSQGTVSRVSTESSAMDPATVAPFTTQNRSRLGSFAGGASSAGFTNSANSTTSNRPYGSDIGSSNLLPLTSKQMSLHQDISVNRELNALPTLSQGTSSLTSSLDARYTTTFDTAQTCAMTFIIDQSQCEAFSRGDPAVTELLRAQAAARVKNAREQAQNQAQDESQKKKQQEQQRPPPAQPGRPQQIGHTTCNLAQCFPAPVTPGAIDIQRPETLHRSPGSTKTVAKALEISAPRSSAQTTNQHQVTEMPENHLDHPQLELRAFPDGNGNAPHGKVTVFRVNPVTSEGTTGAQSAQNHRQEMPGQRRAQETQVQIQQLQVQQIQPPQLQGGTRGQAQNLHVQSNALVLNPQTVQPRYVQNLGTQQWSPVAPSLQWTGSHAQNHIISQAIVPQSMAPQWTGSQAQAPMMSQWAGSHVQNVIIPQSMTSQSMPPPSMPPLPMTPQSIAPQSMPLQSMPLQSMPPQPMTPQSMPPPSMAPQSMISQPMPPQSMPPPSMTSQPMTPHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKZ0</accession>
    <name>A0ABR3YKZ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fructose-2,6-bisphosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">FBP26</name>
        <name evidence="4" type="ORF">Cpir12675_006172</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000261">
        <property type="protein sequence ID" value="KAL1888461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003094">
        <property type="entry name" value="6Pfruct_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013079">
        <property type="entry name" value="6Phosfructo_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606:SF44">
        <property type="entry name" value="6-PHOSPHOFRUCTO 2-KINASE_FRUCTOSE 2,6-BISPHOSPHATASE LONG FORM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606">
        <property type="entry name" value="6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01591">
        <property type="entry name" value="6PF2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000709">
        <property type="entry name" value="6PFK_2-Ptase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00991">
        <property type="entry name" value="6PFRUCTKNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphofructo-2-kinase" evidence="3">
        <location>
            <begin position="9"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="443" mass="51172" checksum="BFD64D0CDFAC7F16" modified="2025-10-08" version="1">MAQSNRRRIGVQAEDARICVVMVGLPARGKSFIAQKAQRYLQWLSIDAQVFNVGNYRRNDAPQPTADFFDINNTEGERMRKVAAEAAVADMMKWFKGGGVVGILDATNSTKERRKWIHDMCTAEGVEVIYVESKCDDEDLIMANIRDVKTTSPDYRGQDPEQAAQDFRNRIRMYEKVYKSVDEDTDESEYTYLKLMNVSKQVIINRIQDYLQSRIVYYLMNLHIRPRSVWLSRHGESMFNLDGRIGGDALLSPRGEQYARKLPELVLNSVGDGRPLTVWTSTLKRTIATARFLPGNYNQLQWKALDELDSGVCDGFTYQEIKDKYPEDFAARDEDKYNYRYRGGESYRDVVIRLEPIIMELERSEDILIVTHQAVLRCIYAYFMKKDHEKSPWMNVPLHTLIKLTPRAYDTEEVRYEAHIPAVSTWRGKGSTAKHEDPLGETI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLG4</accession>
    <name>A0ABR3YLG4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phytanoyl-CoA dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_006082</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000250">
        <property type="protein sequence ID" value="KAL1888673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1888673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="293" mass="32785" checksum="EA7FF97D9D0BE25A" modified="2025-10-08" version="1">MPVLTEEEKEFFVHNGWIHLKGCFSRDQAESITGNVWERLGMAPNDKSTWTRDKIHMGGEKTFNAQEFAPKAWEAICELCGGEDRILESAKWWQDALIVNLGSADKEGQPEAPHDLWGWHVDGDFFVHYLDSPEQGLLAIPLFTDVAPGAGGTVICPEAMPILAKHLYENPAGVSPLMDPRDSPDFRSIEIGKYTSRYSDIAHGCVNFVEACGDVGDVFLLHPLILHTASNNSLRHLRIITNPPIGLKEPFKFYRPEGDYSLVELATLRALGRENLEGWSITHPREGMTPRHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YME2</accession>
    <name>A0ABR3YME2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Short-chain dehydrogenase/reductase family 16C member 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_005866</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000225">
        <property type="protein sequence ID" value="KAL1889220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05339">
        <property type="entry name" value="17beta-HSDXI-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322">
        <property type="entry name" value="PKSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322:SF736">
        <property type="entry name" value="RETINOL DEHYDROGENASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1889220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="357" mass="39049" checksum="257FB6054FF3B6A9" modified="2025-10-08" version="1">MPDISNHNDLQYHDSWFAPISLDMVVKVAKVTIVHPFICWLVPLCLRSQAMSYENPRMQQAIAWAVFITLCWIAGFINNRIAYGLPRHVNLNHEVIVITGGASGLGLLIAEVYGMRGATVAVLDVVELESGEARGVTYYKCDVTDRERLVEVVKEIGRDLGLPTVLINNAGIVVGKTLLDMSVTEIEKSIHVNLLAHFYTLKAFLPCLTKARNGGTIVTISSVLGQVGSAQLTDYAACKAGLSAMHRSLEAELRITHPNMRMVLIEPGQLSTPMFMGVKTPSSFFAPIVEPVDVAKEIITAIDSGKAGHVSTPLYARWIGWFNVLPAGAQRIARYTAGVDDAMKTYVGRGSKEQKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMW6</accession>
    <name>A0ABR3YMW6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005750</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000213">
        <property type="protein sequence ID" value="KAL1889533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046145803" evidence="2">
        <location>
            <begin position="29"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="206" mass="21526" checksum="38F9602749193E1B" modified="2025-10-08" version="1">MKPSTLLLGSFSVTVAMRLGWSPKSCQALDCVGGQLSHDDAIPEVESSNSGAGFAALEYVPQDISTVVTTESPPETTSGAVTTSAPLLPSSAAFSCSPILSTRYIQGNQHCGFSPDLRGRPLTGTGVTSMTSMTSMTSTTSTTSVPPFTTTTREMGGDGCAITIIYIYIMEVCDIIQAVRKVPRPYLGPEKLGADLYDGKMAPAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNH2</accession>
    <name>A0ABR3YNH2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 6">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_005603</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the FKBP-type PPIase family. FKBP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 6"/>
    <dbReference type="EMBL" id="JAWDJO010000201">
        <property type="protein sequence ID" value="KAL1889915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050689">
        <property type="entry name" value="FKBP-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516:SF443">
        <property type="entry name" value="FK506-BINDING PROTEIN 59-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="8">
        <location>
            <begin position="22"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1889915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="116" mass="13047" checksum="B9E976B976EE84A7" modified="2025-10-08" version="1">MEARQVQKKLIQDGQGDTPSRGDTVVIAYAGYLKDDTQPDQKGKLFDSRPDFTTPIGEGRLIQGWEEGVSRMKVGEKAILQIPSEMGYKERGFGNIIPPNSDLIFDIHLKEIRKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPG5</accession>
    <name>A0ABR3YPG5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ATP-dependent RNA helicase DHX35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_005655</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000205">
        <property type="protein sequence ID" value="KAL1889770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF136">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX35-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="31"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="5">
        <location>
            <begin position="234"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1889770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="695" mass="77195" checksum="F2FF21D390FB5339" modified="2025-10-08" version="1">MADFDLDSSFIPALHKPAALLPITKHHDSILYVIETYPVTIIIGQTGSGKTTQIPQFLYHGGWCNNGKAIAITQPRRVSATTISMRVAQEFGCPVGKEVGYAVRFEDVTSQATRIKFMTDGLLIREALMDPLLSKYSVIMVDEAHERSISTDILLGLLKKIRRKRPELRIIISSATIQADLFLRFFETLPNGAPDEKSNTPKTPIGRIVNIEGRTFPVKTFYLNQPTEDYVEKSVQTVLELHSSEGVGDILVFLTGRDEINKAVDTVLESAERLSKDTRKLMALPLYAGLSSELQMLIFDKTPPDTRKVIFATNIAEASLTIDGIVHVIDCGFAKQRFFTPNTRIETLTRVPISKASAAQRAGRAGRTQPGKCFRLYTEASFDELPESNIPEIQRTNLAPIVLQLKALGIDNVARFDFLSPPPAVQMAAALELLHGLTALDDYAKLTRPLGLQMAELSLDPMTARALLAAPDYGCLSEMLTIAAMTSLGGNVWIVLENERHEMEEVRRLFAADEGDHLTLLNVYTAFVTVGRRDSKFCHSHRLNFKSLVKAISVRIQLKRMLEQFNISVNEPSYLSALMTSSSVSDNRGRKTIPLPSRPSAAEAKAKSEKIRRCLTAGFFANAAKMQPDGTFHSVTGLVFYPHPNSLMFGRKADWVIFHEVLETSNKTYIRDVSKVEMDWLVQAAPGFYQVKSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPX3</accession>
    <name>A0ABR3YPX3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ATP-dependent bile acid permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_005588</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000199">
        <property type="protein sequence ID" value="KAL1889942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18596">
        <property type="entry name" value="ABC_6TM_VMR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18604">
        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF415">
        <property type="entry name" value="FI20190P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="283"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="332"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="461"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="920"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="998"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1073"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1098"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="284"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="636"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="998"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1272"/>
            <end position="1532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="384"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="843"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="388"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="847"/>
            <end position="868"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1889942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1533" mass="170327" checksum="ABBB49F21B3CB368" modified="2025-10-08" version="1">MDICSRCLGDIWIPHQAAFSQDCIPLLSSLPTALTFAALAALSLRHVWKYRPVWMRNFAAEDFDDDWRVLQEWAPSSPHTCSRLRFSTKWLMCFVSLLGAGLSLGLFLHHHVVVFMASLVPMIITAAWAASLPHNYSLPVGLLVIQAGLFAIQLAILLGMPVDYQTRNLVVSWLLNMLPSLCLLVHLLQVPLRPHWASVDGIAAPFESPSNEKRSPEDNFTVWQWMSVCWMNPLISLGNTRQLNSDDVWKLPLEFQHARLHSCFANLQGSIVVRLLKAHGSDLAITTFLAILETGLSFSTVVFLRLLLGALGAEPDITPSDSSIYGGNIRAAIVYAILILIANVACAQSELFSLWFCRRAYERSRGEMITMIYEKTLNRKAFTFPGNKADDSNRKAADADQKQKEDQNAPASTGKILNLMRNDVYEISQRLWEFPEIITFPLNLVISTTLIWRLLGPSSLVGILILIAAQSFNALLLKTIYSWEYIRRGVSDTKLQLVSQFIESLRHLRWYDWQDSWLAQILEVREKELRFRVWNGLLMKLITMTNRAAAYTFPVVAFWAYTVVGGNKLTVDLAFPALSLFTILQSSLRQLPDLITTMLNAAVAMGRIERFMAEPDREIISGSIHSQIDINKPAVLEIKDAWFSWPGNAVNVLEDVNVSCSSGLTAVYGRVGNGKSALMHALLGELDRHVGSVSVPNEMMAYCAQIPWLQSMSIRDNILFCAPFDEKRYRLVLDACCLLPDLASFKAGDLSSIGENGIGLSGGQKARVALARAVYSKARILLLDDPIAALDHHTAESIMQKLFSKSNLMKGRTIVIATHRVDIVKPYVTQELEIIDGKVVQHVSPPMSETGSPTTSRDSSITGKSLVQSSSSSTHEDSDDSAEEGRFKDAIPDKFIEEEHRTHGSVVSKVYWRYIKAGKLYWWLAIIVGFLTYRSVNVLYYYFLKIWGEGYKLSQNLQLHAFYHTSSINSQILNLPDVESLLKRYMNLPSPEDNVKPWLFWFAILSLIMVIAQVIPDLVLLALSYTAGRTIFRQAMHRISTSTFRFLDVTPVGRLMNRVTSDMSSVDGSVSANIFYCVWHGVTWTSAMLVIAMTAPAFLVLAIIMTVIFVLVFLSFLSCSQSLRRLEMVSLSPLMSNFGTLVEGLITVRAFHKQSHFRDANIKTTDAFQQMDHFYWSLQGWLQSRFDTMSAVATFALTLAAILGSHGSGTVGFVLAAASNFVSTTHVLCRRYGQLQMEFVSVERVIELLDLDQEAQGDIKPGPEWPSPTDDVVFDNVTLRYAPHLEPSLQNISMRVPAGSTVAVTGRTGSGKSTMALALLATLAPELAAPYSDTEPETATSSLLDTTIAESEACQVPSSPGSIWIGDVDLSRVDKHILRQRISFVAQDPVLFPGTLRDNLDPANKYSDSECEAVLERVMRGSGSFSLTSLVDAGGKNMSQGQRQLIGLGRAVLRHSPIVILDEATASIDMETALYIQNVLREELQNSTVFTIAHRVEAVRDADFLVVMDKGRLAYAGPPLAQATTAAAAIETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQA2</accession>
    <name>A0ABR3YQA2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vacuolar membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005452</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000187">
        <property type="protein sequence ID" value="KAL1890282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022127">
        <property type="entry name" value="STIMATE/YPL162C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31735">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEIN YPL162C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31735:SF1">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEIN YPL162C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12400">
        <property type="entry name" value="STIMATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="354" mass="39498" checksum="CE0D69AF24C7116E" modified="2025-10-08" version="1">MGLSMSTASTITADISSTTIPTASSANSGSGSSLLMQKPGDCELLGSFALFVQLALGALAMMSLVWKRYRERPQRPVKIWFFDASKQVFGSVLVHSANVFMAMLTSGRLSVKLQPRTMYHMRSMLMRRDDDPEAYQPNPCSWYLLNLAVDTTLGIPILIALLRIYTGIVARTPLGKPRESIQSGNYGSPPNAWWWFKQSIIYFCGLFGMKVVVLIIFVLFPWIAHVGDWALSWTEGNEELQIIFVMMLFPLIMNAMQYYIIDSFIKKQDPNHHAHDSLGRHSLVPNSDDGDDRPSDDLSSENEEDIADLHLSKSRTGARDGIKTDNDEYDPVRDGDTSTIFGSSSDHSQNTSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR47</accession>
    <name>A0ABR3YR47_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Gfo/Idh/MocA-like oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005389</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000183">
        <property type="protein sequence ID" value="KAL1890465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051450">
        <property type="entry name" value="Gfo/Idh/MocA_Oxidoreductases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43377">
        <property type="entry name" value="BILIVERDIN REDUCTASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43377:SF12">
        <property type="entry name" value="BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11840)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="1">
        <location>
            <begin position="9"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="517" mass="57072" checksum="C2868882FD23B48F" modified="2025-10-08" version="1">MKQPTSPARFLIIGAGSRGNAYGKGIKDATNGVIAAVAEPDSYKRQRYGQKFIWGDGGTAGEGQAFTDWKDFIVYENERRKRAVRGDANVPPGVDGVFVCVLDEMHHEVVVALGPLNLHVMCEKPLATSLQDCIDMYKALQTSPESGPQRSVFSIGHVLRYSPHNVLLRRLLLEKKVIGDILSVVHTEPVGWWHFTHSYVRGNWRRSDMTGPSLLTKSCHDIDLILWLLSSPVHPGKGRPHLPTTVSSIGKLQHFRKARKPKAAEGATNCTKCALGDEGCMFSAKNVYLGPKLQGVGSGNTGWPVRIVLPDIEAYSTMEAKHAAMLTELQKDYAPGTQDEIVRSRNWFGRCVFDGDNNVCDEQVVTIQWEDDQVQEAGADGGNRLAKTATFHMVAQTHKICQRYSNFYGTAGEIHADSRIIKVTDFRTSQVTCHEASTEDAGHGGGDIGLSIQFVHAVNSVKNGELSAEDAQLKFMGCTLEEVLRSHAMVFAAEEARLSNKVVDWEKWWDAEVQTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSB0</accession>
    <name>A0ABR3YSB0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Checkpoint clamp complex protein Rad1</fullName>
            <ecNumber evidence="6">3.1.11.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rad1_2</name>
        <name evidence="6" type="ORF">Cpir12675_005228</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the rad1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.2" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000170">
        <property type="protein sequence ID" value="KAL1890832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008311">
        <property type="term" value="F:double-stranded DNA 3'-5' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00577">
        <property type="entry name" value="PCNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003021">
        <property type="entry name" value="Rad1_Rec1_Rad17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10870">
        <property type="entry name" value="CELL CYCLE CHECKPOINT PROTEIN RAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10870:SF0">
        <property type="entry name" value="CELL CYCLE CHECKPOINT PROTEIN RAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02144">
        <property type="entry name" value="Rad1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01245">
        <property type="entry name" value="RAD1REC1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1890832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="347" mass="38259" checksum="BE282FCE544CB4D9" modified="2025-10-08" version="1">MAPQTGGTQVAPPLLFKAVTSSTKPLFQLLKCINFTNKVHVEITESGLRISADNARVMQGVAMLDRSLFSSFQLNLDTSNGGNDDDSDDDDDNSVPAIPSFQINFASFLETLQILGSVDLANRAAKVEQDAYRSTTRNYRPEAFSNQALGIAGSCSLVYSEHGAPFSIIIEEAGVKTTANLTTYSPEMPEEIPFDRADLMFKIIMPPRHLLDAFAELAIMAPAKLVISALPTQPWLVLTGRGGELGASSYDFSRARELMESAVVRAEWAQTYRFDLVRAACEAMRIANKVSFRGDRQGVLSLQFMVEVEGADMNFLDFRFVPFVGYDEDEEAEDEYEEDPSEDEVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSE2</accession>
    <name>A0ABR3YSE2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Autophagy protein 7</fullName>
            <ecNumber evidence="4">3.5.4.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ATG7</name>
        <name evidence="4" type="ORF">Cpir12675_005237</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.12" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000171">
        <property type="protein sequence ID" value="KAL1890812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004132">
        <property type="term" value="F:dCMP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01486">
        <property type="entry name" value="Apg7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.100">
        <property type="entry name" value="Ubiquitin-like modifier-activating enzyme ATG7 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.70">
        <property type="entry name" value="Ubiquitin-like modifier-activating enzyme ATG7 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032197">
        <property type="entry name" value="Atg7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042522">
        <property type="entry name" value="Atg7_N_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042523">
        <property type="entry name" value="Atg7_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF3">
        <property type="entry name" value="UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME ATG7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16420">
        <property type="entry name" value="ATG7_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like modifier-activating enzyme Atg7 N-terminal" evidence="3">
        <location>
            <begin position="10"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="2">
        <location>
            <begin position="368"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="603"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="701"/>
            <end position="722"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="722" mass="80122" checksum="5FB75720A739E415" modified="2025-10-08" version="1">MTEPLVGNPLQFVPLSSEIELPFYSALFSMKLEHDMLDDSARTITGAYEARVSRPEDSCKVQVAGNSLTSQYTAPRGSGRADGTLRNTNTWEGFKNLDRSALLKHSAKQIWDAIKDGTIYSVPSLLSSFILISYADLKKFNYTYWFAFPALHSSWIHAAEIAHITSQESTALVESVDGWQYRVKDPRQHGFFIAKKVLRSTLNEDGDEATEVATENRSFAGFDDEEEELPYVWVVDSIGSFDRGFFDGVADEDRFVGFLDSSNYARNPGWQLRNLLVLIQRRFKMNKVNVLCYRDIHSHRDAARTIIMTLQAVDKADEPLQAADIPKVTGWEKNGPTFKYKRVSLAAYMDPMRIADQSVDLNLKLMKWRLAPNLILENISRQKCLLLGAGTLGSYVARNLMAWGIKNITFVDYGKVSFSNPVRQPLFVFKDCLDGGAPKAPTAASALMEIYPGVTSVGHQFAVPMLGHAMTNVENTKADFEKLQRLIEEHDVIFLLMDTRESRWLPTVMAKAAGKIVVNAALGFDSYVVMRHGTEIDDAQVAKTGQKPLGCYFCNDVVAPSDSMRDQTLDQQCTVTRPGIAPIASAMAVELLASLLQHPLQGKAPAPKTTGLHAEREPPNHPLGTVPHQVRGFISSFQNVVLRGEAYPNCSACSPIIVDSYRCDGWNFVERALREKDYVSELSGLAELHRKAEQMTADMEWDSEGGSAGCSSIGSDGEGDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSQ3</accession>
    <name>A0ABR3YSQ3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005183</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000167">
        <property type="protein sequence ID" value="KAL1890917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42055">
        <property type="entry name" value="YALI0E03476P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42055:SF1">
        <property type="entry name" value="YALI0E03476P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047093447" evidence="2">
        <location>
            <begin position="23"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="515"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="523"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="535"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="652" mass="72820" checksum="753EE54E7F9A5B61" modified="2025-10-08" version="1">MGTKQLPLLLSALLMLILFSIFVNEPHNVAPAGSDAKKPDNEPTTEHKFMLPTVPNPFHDVTNVLNPFRAPVHAPPRQKNDTDGESSWWSDWKWLVPFSSSLTLDEDRSLLPPLKPRPPIYCYYDTTTKKDSATKDAESALLLTWRRAWWAKGFLPVILSAAEATNNPLYDQLQRLTMDPAVKTQLTRWIAWDTMDGGILAEYTLLPMGQAEDPLLVYLRNGEYSKMTRYSGLDSGLLVGPQADLTKTIKATLESKQLDSAKDVFHAAPSNLFVTDEGSQAIAYYDVAVIQDKYNEISKVMATDKADGLRKLNELINSHLHQTWQGIFSKGLVVLQPKPEHTGFIVKNAVSIANDLVTCSPTPLSTGSCPPNMPECVQCSDSTRMKLTTGEFIVNSTSLYTIGTVPHPYTFVSMVHITNAIDTKWILKEMTVRDPWLTKITENIFAKPASRNAMLMRFKEAVAGEYAPSHSLWMSAEKDAPADINWHFGFAIPQAKSETLKNVKVPSLPVLAHDAQHKAKVKRAGDEKDEKKAKTANSPEKSNSDSTDLIREATLLQKALSIGNSRDANDVKIRNALEAWNLADLEAWKFARAFLARRIVERQQWETEESKYVQGLGTEQGRRTRWWDNIEDKIAGVGGKTSDTKDGLNKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTG0</accession>
    <name>A0ABR3YTG0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peroxisomal membrane protein PEX17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004854</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000148">
        <property type="protein sequence ID" value="KAL1891668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055334">
        <property type="entry name" value="PEX8-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39214">
        <property type="entry name" value="MICROBODY (PEROXISOME) BIOGENESIS PROTEIN PEROXIN 8 (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39214:SF1">
        <property type="entry name" value="MICROBODY (PEROXISOME) BIOGENESIS PROTEIN PEROXIN 8 (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26001">
        <property type="entry name" value="Pex8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="703" mass="73898" checksum="FDB6303090DBB677" modified="2025-10-08" version="1">MSTHAMLNHVLALFQQPQPPNTVSQIHGTCVSLLSTLSNPLNITVLTAHLLTAPAIWHRPGTGLEPPLAVLSIFNAAASRLQANPGPLSCSAWAKAVARGTDARAAHWQHALVFSGILIGFSAPPPPPTTPSLSSHKTPEASLPRPLSPSMRHTLEISLVKAANLALLRPLQDGPLAADSLVLALTHVQAHLSPRAVSQLSFSTLLPLAISALGGAQSFDGWSFFAPIAADVVAASPPNGPISWPATSPSFAAVQALASQPIPANLGPLANLAALAIRNAADPDAVVRAHEHLISLTQALWESWQRLPFAQIEPNNEDTQLAPETAGVTAPALRTLLQKYLFATTAILNAVMARCVLDASLRRPDTASQLAAGTLRAMRDLFFVSMRDGNAKFQIYRFTYLCAVDVLAHNPAAAAALLARLKPAPASTMSQNSATATVGAVPLDMPTRLLDLFYLNLAEQLSLALATSDADLLIVQPASTYLSHAAPASPVMRELFEAAHSAVLSVLACPQHAALASSLVPYYAAQLLGAFPALVSPRQFRLAFATVLGILAPPLPASAAAPGLAEALVETVRHRAVDMPSTGKTPLPPLLGEEETMQAPVSEQTGLLLALVDALPALPLGVVDEWLAVTAEAIAAVEDENLKIPLAKRFWEVLESGEFDVERSMVAVEWWARGGAAVLGTRKSRSVVTMSGAATGLKDGSRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTP2</accession>
    <name>A0ABR3YTP2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nitrile-specifier protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_005011</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000157">
        <property type="protein sequence ID" value="KAL1891327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47435">
        <property type="entry name" value="KELCH REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_5G12780)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47435:SF4">
        <property type="entry name" value="KELCH REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_5G12780)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="120"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="131"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="142"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="570" mass="60339" checksum="0B2F3A259CEB32B1" modified="2025-10-08" version="1">MESFAAIKRRTTDILQSLPQSLPHNLPSLAIPTLPALPTLPSLTPRDVTGSWEKINGVPHLARSSHSLDIVGGSAYIFGGELDAREPVDNAVHVIGLPYSGASADYYTIPAQPLAGHRHNEQVDQANSGGEDSKAAGKEADTASTPDPKTSRSSQEDKPDSDADDANETSATATPADKEPKELAEIPLSATFNKFAAIEKNKVIDDRPQLEPVPAPRVGHATAVIGNRIFMFGGRGGPAMIPLDEGGRVWVFDTRVGRWSFLDPASPAPGVLVIPRPAPRSYHSAAAFSAPRDFKPLGLRRTKTWAEWAAGDSAEIGTPQSPIVGNIAANATDEDNEGFGTFIVHGGCLAGAGQRAADVWAFDVRSCVWTQLPVAPGVARGGTALCASGNRLFRFGGFDGKHEIGGQIDVLTLGEDHSGLEPVLVATTEWVTLSQPTAEDGAPLSQSPWPKARSVAKLVLLSPAGREMLVLLMGEGQASAKGHESAGKFFSDVWVFQVPAAVKSGKMAEGKWAQVTVSPHDSEVSAELPTARGWIDAAPMAETEENGILIWGGLGEDNNRQGDGWIFRLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU53</accession>
    <name>A0ABR3YU53_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PRP16</name>
        <name evidence="10" type="ORF">Cpir12675_004824</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family. DEAH subfamily. PRP16 sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000146">
        <property type="protein sequence ID" value="KAL1891783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF91">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE PRP16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="286"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="474"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="233"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="938"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="52"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="960"/>
            <end position="974"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1891783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="974" mass="110282" checksum="84C7E243D6A52699" modified="2025-10-08" version="1">MEESEYNGAMPKRRKLNNTRHNNAEHDRLRNGPRGRRQQSYHDRQSTPSPPHKNEEEERALDRDWYGGDEMGGHVFGDDSHNPFADYDSHELQKTETAMAERMSGRYDARKEQRQRENDAWETNRMLVSGVAQRRDLASDFDDEETIRVHLLVHELRPPFLDGRTIFTKQLEPVPAVRDYQSDMAVFSRKGSKVVKEARQQRERERQAQAATSMAGTTLGTIMGVKDEDADSALPMADEGEGKKSNNNKFSQHLKKSDGASNFSQTKTLQEQRQYLPAFAVREDLLRVIRENQVIIVVGETGSGKTTQLAQFLNEDGYASQGMIGCTQPRRVAAMSVAKRVAEEMECPLGGTVGYAIRFEDCTSKDTIIKYMTDGVLLRESLNEPDLDRYSCVIMDEAHERALNTDILMGLFKKILQRRRDIKLIVTSATMNSKRFSDFFGGAPEFTIPGRTFPVDVLFHRSPVEDYVDQAVNQVLSIHVSMDPGDILVFMTGQEDIEITCELIQKRLDALNDPPKLSILPIYSQMPADLQAKIFDKAAPGVRKCIVATNIAETSLTVDGIKYVVDSGYSKMKVYNPKMGMDTLQITPISQANASQRSGRAGRTGPGKAFRLFTDKAFKDELYMQTIPEIQRTNLSNTVLMLKSLGVKDLLDFDFMDPPPQETITTSMFDLWALGALDNMGELTDIGRKMSAFPMDPSLSKLLITSVEYGCSEEMITIVSMLSVPNVFYRPKERQDEADAQREKFWVHESDHLTYLQVYLAWQANRFSEGWCIKHFLHGKSLRRAKEIRDQLTDILKMQKMPLSSCGMDWDIVRKCICSGYYHQAARYKGSGEYINLRTNVAVQLHPTSSLYAGHPPDYVVYHELVLTSKVYVSTVTAVDPYWLADLGGVFYSVKEKGYSAQQKKTTETEFNRRMEIEAQMARDKKAAEDKKLAEKLQVEKKTGADPSSGSTKKVVQRGAVRKPVAKKRFGRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUF9</accession>
    <name>A0ABR3YUF9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cellobiose dehydrogenase-like cytochrome domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_004792</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000144">
        <property type="protein sequence ID" value="KAL1891903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09630">
        <property type="entry name" value="CDH_like_cytochrome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015920">
        <property type="entry name" value="Cellobiose_DH-like_cyt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16010">
        <property type="entry name" value="CDH-cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046932972" description="Cellobiose dehydrogenase-like cytochrome domain-containing protein" evidence="2">
        <location>
            <begin position="28"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="Cellobiose dehydrogenase-like cytochrome" evidence="3">
        <location>
            <begin position="33"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="346"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="430"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="555" mass="56372" checksum="8EC480CC67DA8533" modified="2025-10-08" version="1">MAYRTLSFFSASSMFLGLLPAIASVKAESASTFTDSKSGIVFQRFWTQQSSFGIALPESVESSFIGQIAVPLIKGAGWGAIGLNGAIDSNIFVAAYANGADVTGSLRNADQSEVTGDYSIRTIGEFTSVDKSSLLYTFLCENCLNPDVGAVLNGAGDTATLGFGLSSEVVSDPTSTSATLGPANSGNGTFSISLAAARNAEFPAWAALATPKPSSAELKKRNIEERSPFDVEALPPLARSIAEESHRIDRRHKNGTGRKKNRIGAASRRNRSKAAKSKNGSTGAADKAAAKERIAKAKAKAEQAIASITGKAQSAQSINLFDTRSTDKSNKVNKRHANGGRKKNRTGAAKAKQAAAAAANADANTNAGTRANANTGGGHTHSAARSISLLDTRDVVNSESLPATARSVDGESRMAKRHGAGGGGRRRNRTGAARAKQAAAASSRDQSANTVAVREPMPEPHTQAGGGGGGGAATAGAGAGAGAGAGAGAGAGAGAGAGAGAGTGAGARTGVGPQRGGGRGGNRVQRVRKFAEDFLRSRAVPEEELENNDDDDDFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUN2</accession>
    <name>A0ABR3YUN2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_004817</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000145">
        <property type="protein sequence ID" value="KAL1891812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12246">
        <property type="entry name" value="RRM1_U1A_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="23"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="140"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="140"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="178"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="189"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="206" mass="22031" checksum="66B3451132886A75" modified="2025-10-08" version="1">MAPVVPAKLAGNAAIPVKVVPNQTLYVTNIPSAKITKPDLRTELYLLFSTYGAVLDVVALKTQKMRGQAHIVYRDIQTATQAMRALQGSEFLGLELKIQYAKSKSHFISKLDGTFKMPGSTQGAAEVVVTELQASIFNAPTPGSKQAITESKSAHINSGAATTSGPDTTMRETTPADARGEKRTRNEESEASGDSDVAMEEDSDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUW8</accession>
    <name>A0ABR3YUW8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">sphingolipid C(9)-methyltransferase</fullName>
            <ecNumber evidence="14">2.1.1.317</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">MT2</name>
        <name evidence="16" type="ORF">Cpir12675_004791</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CFA/CMAS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.317" evidence="14"/>
    <dbReference type="EMBL" id="JAWDJO010000144">
        <property type="protein sequence ID" value="KAL1891902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052290">
        <property type="entry name" value="Sphingo_C9-MT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45197:SF1">
        <property type="entry name" value="SPHINGOLIPID C9-METHYLTRANSFERASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45197">
        <property type="entry name" value="SYNTHASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G04190)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02353">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 16" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="10" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="7 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00039020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1891902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="516" mass="58734" checksum="7EF3F2DBA95F0B72" modified="2025-10-08" version="1">MASQKSDFEFSSTPPFSGDKFVKAEPCGVRTTNYPTIHNAPLPADGPGSDTFSNLGMGALLFLVPYYASWKVGGGIKTTFFFALFTTVPILLVWWLVISAIAPRRNEKAQLPGRPVEFYLAFKNTPDRLKYRGKNKIPMETFLEMYFDGLVEFNGDALEVLEWRHDWASFRFTWGMLKFVFTGLLPEAIMHTHEEQVRDHYDRGDDFYGWFLGPRMVYTSGIISDPDREETLEELQDNKMAVICEKIQLKEGESILDIGCGWGTLVNFASHNFNARATGITLGRNQTAWGNSILRKSGVPEEQSNILCMDYRDIPVPEGGFNKITCVEMAEHVGIRHFTGFLTQCYNMLDDDGMMFMQLAGLRKSWQYEDLNWGIFMNKYVFPGADASTPLGFYISSLEAAGFEIKSIDTIGVHYSATLWRWYRNWMGNRDKVEAKYGKRWFRIWEYFLALSTIVSRQGGATCYQITVVKNLNSSHRVEGINSQWGLLGSIANTRANLSNWASRMNNIRSSKEVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV97</accession>
    <name>A0ABR3YV97_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004582</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000133">
        <property type="protein sequence ID" value="KAL1892296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="102" mass="11440" checksum="669FFE42E8834F3B" modified="2025-10-08" version="1">MHREYTQVTHDKRKGDLKPGKFVKDKLEDESESSSSYEHTDSDSGSDISLGLPGYRLASGPGIQYDWSLCSDDCFWCGYIGLHDETAELSEELAMAMSRLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW19</accession>
    <name>A0ABR3YW19_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">60S ribosomal protein L5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RPL5</name>
        <name evidence="7" type="ORF">Cpir12675_004472</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000127">
        <property type="protein sequence ID" value="KAL1892584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00432">
        <property type="entry name" value="Ribosomal_L18_L5e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01337_A">
        <property type="entry name" value="Ribosomal_uL18_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005485">
        <property type="entry name" value="Rbsml_uL18_euk_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057268">
        <property type="entry name" value="Ribosomal_L18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025607">
        <property type="entry name" value="Ribosomal_uL18_C_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23410:SF12">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23410">
        <property type="entry name" value="RIBOSOMAL PROTEIN L5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14204">
        <property type="entry name" value="Ribosomal_L18_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17144">
        <property type="entry name" value="Ribosomal_L5e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00058">
        <property type="entry name" value="RIBOSOMALL5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL18 C-terminal eukaryotes" evidence="6">
        <location>
            <begin position="268"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1892584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="330" mass="37619" checksum="1ABCE8FFF3608B96" modified="2025-10-08" version="1">MKLDGQFGPKTHGIWQKRLNLESMQDASDILQNLKRKLLTLLFRFQTKYKRRRQGKTDYYARKRLITQAKNKYGAPKYRLVVRFTNRDIICQIVSSEITGDKVLAAAYSHELRAYGVKHGLTNWAAAYATGLLVARRVLKKLSLDEQFPGVEEADGEFTLTEAIETDNGERRPFKAFLDVGLTRTSTGARVFGAMKGASDGGLLIPHSEKRFPGYDVESKELDADTLRNYIFGGHVAEYMETLADDDEERYQGQFCKYLEDDVEADGIEDMWTEAHAVIREDPFKKVESDTPKKTKAEWAAISKGYKVKKLSLEERKARVAQRITELRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX02</accession>
    <name>A0ABR3YX02_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphatidylinositol-specific phospholipase C X domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004574</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000132">
        <property type="protein sequence ID" value="KAL1892421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08586">
        <property type="entry name" value="PI-PLCc_BcPLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051057">
        <property type="entry name" value="PI-PLC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593:SF113">
        <property type="entry name" value="SI:DKEY-266F7.9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphatidylinositol-specific phospholipase C X" evidence="1">
        <location>
            <begin position="115"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="389" mass="42890" checksum="41F05BBEA3BAEF19" modified="2025-10-08" version="1">MTPDLSANGAESFSNRQSHKTVSCCAWLPFSMANLSPRAVSRWTAVVLACVVLLTLNSLTNGMRLLMPCVESPTQHCYRGYTSAWSFNTVEETTPPVPPPPQAEWMSGLPDAANISSLSLPGTHDTMTFSIPDEKLQCQNHNLTTQLIAGVRYIDARTRLQGDQLGIYHSHQSTGHTLAEVMTTVFDFLDARPSEAIVVRIKEEGPRLGNGTKSFEEAFNALRLDSPDLAPRFEKHLYVKPNPLAPLPTLGEMRGKIFILQEFPATEEYGIRWRSTHIVLEDLWIIPSLPHLEIKWEAIHRALVRSATEPDSNTALYLSHLSASIGVLPIEAAAGPLDGTVVGMNDRTGTWLEKQPKARRGIVIIDFPGQALLDAVIGQNAPLMQASRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXB6</accession>
    <name>A0ABR3YXB6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004477</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000127">
        <property type="protein sequence ID" value="KAL1892589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="481"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="195"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="631" mass="67400" checksum="BD29974C982F2FFE" modified="2025-10-08" version="1">MSSHDSSSEAPKARNTSSVEPAPRSAPLYRAMPYPTTPKQLPKLVPKLPARPQGQQQQQQQQEKPAPLLEASQPFPPTAPLLPPSASPALGSPSRHGAQPQMFKKAKPRKKMASVALAKTSRWIMSDDLLHRFRKVEAQEILTEDQIRKLKQSREAAEKESRPTESEAAQDANSTETLADNAEGAGSSELSPKQTSVFPSSSPPSTSTLSQVPKRNQASASSLSSPPAPVVRHDFSAPSKSQNSNDAKSLPPTPRSPSLARHTALATIPEVTLTAPPGSSEPSPTTNSPFSTINPISPVSVLSASTSDGIESATPRNDSISSVTSAASAASQYEPSEDDEYIYFHGAPTSATTPTFRHGRIRISKAESGIRMSGENNLDWTAFQMAILGAGDWFSDLTSNDITSPVCEVGDVDDLADWFYGLNLPDCPEPSANDDAPPMMPPAITEVAPADADCPPPPYSASEYDAAGGKSARLYSALGKDPSEFNSEYHSDASPPPSLSSTPRSSDDIPRSSACIFPPAPTPRCQPSPYDGAPWSPPRHQKYSHQINLSVDSARNVRRPSATGGYPSPPRQLCMMASNESLVSLPQSPMPPIAKSPADEADFIPMGYNLGHDLGDFLRWEAQHVYASSPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXR9</accession>
    <name>A0ABR3YXR9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000129">
        <property type="protein sequence ID" value="KAL1892543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="319"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="32"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="54"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="76"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="201"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="224"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="239"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="249"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="699" mass="76686" checksum="8E4F79C753F0F11B" modified="2025-10-08" version="1">MADPISKRRRTSPRTSNQIRPETEVPNDADTAKNTDTNPAQTPKSPSKRPASFASPTKASLSRSNPEILARHSIAPSDTETNTSNGHSRPSNGLSQTHIAKSNGSSEEQTLGAVTAAAKPKRGSLFPSVAKSLARRLSERPRRSSSAKPSNPEDDAVDPFRGNTLRRSGAGLADTRIAEPDSEPELPPTPVQLGLDDPVVTTPSTEIHNSTSPSRRGRKRKQSESIISTTPSQLGQIAESHDEPRPENESNNPKSTQIEPNRAPFISPTRAKKAAAKQYAAKMAASGMQAKWTAPKTRSHRHTQDLIDPARGIVPRDAYWEKRELIEKLKREAALLQADLNFAKSENDRIRAEVLNQRETRVADEGNHTQGAQVLELLKSYILPPEKPAEPTLSQQMLYAALNTMSWLPFGDSITLPTLAQPASEPEPEIKSHKPIKMMADEEKPFLTLFTPLALESKIVLLEQKSTAEPLLMKHSIDVSSATNPGAFAAQIEMTVDSQKLVITDLSVPKIDIRAQAELGVFINTVLQTPRNRSLKNNICVISWAMAEWYRVATHRARVWCTLATELGNAESIRTLVKKTRSAKRPHRNMSMSDEQEAPQLSKTDLIAYMDKTAMDIPLVLPGNGEMMARIQWIIDFDWTGEAVSSASLMIGLPGKWQKADKRGTLPQISKLFNELVAGNNDVLAASRTIVSLLAGQSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXZ0</accession>
    <name>A0ABR3YXZ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_004193</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000113">
        <property type="protein sequence ID" value="KAL1893260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33266">
        <property type="entry name" value="CHROMOSOME 15, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33266:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1893260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="426" mass="47563" checksum="852492CD0127FEB2" modified="2025-10-08" version="1">MDLEYRHWGTLRLARSVRASGVSADAFFRLQIGGGDVGKRDVITSALELVIKKPPFNSPTIEVPNPQTNWQAFDGHCKNAFTTPGPQEMTNDDANSSTQPLNLEFVICIDEARYQDFDTKTALLALLSYRIPFTISNFALAKTLVSHWMHPLIDVSDDLLGQELYWNHVSVGDMGEFIAGLILFLAFDTASLLRCPEPLPLQGFLKHLLGHPVVGDLSKVSGDSLQSNLGQMLSSGTVFFNRLHRRVTAPSATDIYNMYRACTACYLPSDRHGVDILIPVWVPPGHEREAHVGCMLVRVSNKAYDKFEDDAKTSAYTHTERRFKAIGFSNQMPVIGLMMCLRGQIHSCEVMSDSENAKNNSGIILSVRLDAEHYPMFQGLPEEPETLVKQQVLRHLQSMLSEVDTYAADKNKNARKLFLFETGCLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYM2</accession>
    <name>A0ABR3YYM2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Hexose transporter hxt5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">HXT5</name>
        <name evidence="11" type="ORF">Cpir12675_004377</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000121">
        <property type="protein sequence ID" value="KAL1892843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17356">
        <property type="entry name" value="MFS_HXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF92">
        <property type="entry name" value="LOW AFFINITY GLUCOSE TRANSPORTER MSTE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="393"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="428"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="457"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="35"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1892843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="532" mass="57911" checksum="4A569906BA0B0B18" modified="2025-10-08" version="1">MGFLKKQTDQVEKADPSSSNNDAATQRVTFMACFLGGVASIGGFMFGYVSGQISGFFSMKDYARRFGELASDGTYQFSAARQGTIVGFLCIGALFGSLVAGKIADTLGRRMCISVSAFFCCIGTIVEISSSSQWVQFAMGRLVTGLGIGSLSVAVPMYQSESAPAIIRGVLVSMYQLFITLGIWTAEMINFGTEGIDNSGSWRIPNGISFLWAIILGLGILVLPESPRFAYRQGRVDEARATIAKLAGVDENDRSVSNQITEIRVKLEEEKAAVDTNILEIFTGPGMLYRTLLGITLQAGQQLTGANFFFYYGTTVFSATGLSNSYVTQIILGSVNVVCTFGGLYVVQKSGRRNALMFGAAWMMMCFFVFAFVGEYKLDHSNPQNTPTAGNILIIFSCLFIAAFATTWGPLVWAVVAELYPAKYRAPCMALATASNWLFNFLMSFFTRFIINAIGYLYGLVFAGCCGALVLIVFFFVIESKDRSLEEIDTMYILGINPITSHKWDSSNHVTSAEQTAAEHSGGEMSKDEVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ01</accession>
    <name>A0ABR3YZ01_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histone acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">SAS2</name>
        <name evidence="16" type="ORF">Cpir12675_004062</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4, H3, H2B, H2A and H2A variant H2A.Z. Acetylates histone H4 to form H4K5ac, H4K8ac, H4K12ac and H4K16ac, histone H3 to form H3K14ac, and histone H2A to form H2AK4ac and H2AK7ac. The NuA4 complex is involved in the DNA damage response and is required for chromosome segregation. The NuA4 complex plays a direct role in repair of DNA double-strand breaks (DSBs) through homologous recombination. Recruitment to promoters depends on H3K4me. Also acetylates non-histone proteins. In addition to protein acetyltransferase, can use different acyl-CoA substrates, such as 2-hydroxyisobutanoyl-CoA (2-hydroxyisobutyryl-CoA) or (2E)-butenoyl-CoA (crotonyl-CoA), and is able to mediate protein 2-hydroxyisobutyrylation and crotonylation, respectively.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MYST (SAS/MOZ) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000107">
        <property type="protein sequence ID" value="KAL1893631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061733">
        <property type="term" value="F:protein-lysine-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.60">
        <property type="entry name" value="N-acetyl transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002717">
        <property type="entry name" value="HAT_MYST-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050603">
        <property type="entry name" value="MYST_HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040706">
        <property type="entry name" value="Zf-MYST"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615:SF219">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE KAT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01853">
        <property type="entry name" value="MOZ_SAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17772">
        <property type="entry name" value="zf-MYST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51726">
        <property type="entry name" value="MYST_HAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0007">Acetylation</keyword>
    <keyword evidence="12 16" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYST-type HAT" evidence="15">
        <location>
            <begin position="187"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="58"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="490"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="66"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="147"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="517"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1893631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="586" mass="64741" checksum="1AAE8643566A3601" modified="2025-10-08" version="1">MPTSKRKRAEPASTASQTRDVPDVGEARSLRQTTLAFKRSQQQVGSLLNPHENAVAKAVIERDGGTEEPEDIFMETEPEAQPSKDTEPATLPARKRRRPRKAAEIEQLSELRVNDSSQDATVDPELEPSPPQTRRRTGCTNRRKDASSSSSSTAATATVSAHNLATFTISSITPASATASSNTNTPCADRNIDYVVLGDLCFRTWYPSPYSKDVLGQPSSRPARAHGRKRQAPLLEKLYVCPYCFKYAREVLLWAKHVKFCCSMSRRLYESVPGRKVYVHPTREGETGEWSVWEVDGEKDSLFCQNLSLFGKLFLDTKSIFYDVHNFNFFLLVYSPAPSAPSETTESTVPRITGFFSKEKMSWDNNNLACILVFPPWQRKGLGALLMGVSYEIARREGLLGGPEKPISDIGLKGYRRFWGSEIARWLLSVDTTKVATNAQYSASAAASTSNRSSADVLVDIYDCSQATWITPEDCLTTLREIDAVQDNDAGLQSNKSRSQRPRALQSAETLPGTPASSTSVSSHSVPGQESSQDQKQTRYVYISRDAVRDWVVLNNINMDRVCDPAGFVEGYAIKKTEGGFVGPGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ92</accession>
    <name>A0ABR3YZ92_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PWI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_004220</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000114">
        <property type="protein sequence ID" value="KAL1893242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1390.10">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002483">
        <property type="entry name" value="PWI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036483">
        <property type="entry name" value="PWI_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052225">
        <property type="entry name" value="Ser/Arg_repetitive_matrix"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23148">
        <property type="entry name" value="SERINE/ARGININE REGULATED NUCLEAR MATRIX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23148:SF0">
        <property type="entry name" value="SERINE_ARGININE REPETITIVE MATRIX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01480">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00311">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101233">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51025">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PWI" evidence="3">
        <location>
            <begin position="12"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="124"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="124"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="166"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="203"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="225"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="235"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="260"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="277"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="294"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="304"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="357"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="401"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="411"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="434" mass="49338" checksum="FD672BC0C8A2E0BC" modified="2025-10-08" version="1">MATGVDAKLLKSTKFPPEFNRKVDIQKVNVQVLQKWIASRISEILGNEDDVVIELCYNLLEGGRFPDIKALQIQLTGFLAKDTPTFCKELWNLCLSAQDSPQGVPKELLEAKKQELIKEKIEADQAEEQARRRREDIERRERDQRDRFRGRGDSYRGRGASDRSRCGGGLAGRGGNRSRSPPFWRGRDGGGRPRGGVSSGDHYAPRGREKSISRSPLRSRRRSTSSKASPAPKASRSRSRSKDGSRRKRSRSPARGGSLKSHRPNSRRGRSMSSTRSHSRSRSRSYSRSRSRSCSRSSSSSPTLKRRRAARSRSRSHSYSPARRRRSPSSSSYSSRSRSRSRSRSRSFSSRDSRSPSPKRSRRRYTRSPSSSDDDGKRHNQSRRGSRSKSPRKLKTRTARSRSSTSYRSYPRSRSRSRSRTRSRSRTPRGKSAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1L7</accession>
    <name>A0ABR3Z1L7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA polymerase II holoenzyme cyclin-like subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003667</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000091">
        <property type="protein sequence ID" value="KAL1894438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20546">
        <property type="entry name" value="CYCLIN_SpCG1C_ScCTK2-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="3">
        <location>
            <begin position="132"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="413"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="25"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="415"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="427"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="458"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00014912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="470" mass="52510" checksum="C4A25C7777C43940" modified="2025-10-08" version="1">MTSVEPYRPPRENYQPAGAAATDNAVASSVSLSPLRSPRQASSAGSTSRDSYVLRSPELGETADDNDAASKSKSTVQNNSLTQKTTTIHSLPQRMSLPQRPPAMTDPVPPPPASASTKPRPDAPLQQWCFTEEEVVSTTSVIDGISPAEERLRRAKGVNFIYQAGGLLELPQMTLWVAGVFFHRFYMRYSLVEQKAGVHHYNIAATALFLANKTEEICRKTKDIIIAVAKVGQKNLRLIIDEQSKDYWRWRDSILMYEEMMLEALTFDLMVENPYEHLRDIMLRLHIYPNRTLRQAAWAFCNDACLTNLPLLLSARDVAISAIFFASIHTNQLIDDVDGQPWWVFLHSDEDNCARAIRVLCQFYTENPLRKPIPNVSSPSFVLNSTRRTGEALPRISPASTPISAHEDGAVQWSADANGNGSMSADSESRLYENTETRASPTPSLKRKNSIGEEGDESISKRVRMSEHRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1Z2</accession>
    <name>A0ABR3Z1Z2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">TEA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_003825</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000097">
        <property type="protein sequence ID" value="KAL1894090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.20.40">
        <property type="entry name" value="TEA/ATTS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000818">
        <property type="entry name" value="TEA/ATTS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038096">
        <property type="entry name" value="TEA/ATTS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050937">
        <property type="entry name" value="TEC1_TEAD_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11834:SF0">
        <property type="entry name" value="PROTEIN SCALLOPED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11834">
        <property type="entry name" value="TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01285">
        <property type="entry name" value="TEA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00426">
        <property type="entry name" value="TEA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51088">
        <property type="entry name" value="TEA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TEA" evidence="8">
        <location>
            <begin position="147"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="TEA" evidence="6">
        <location>
            <begin position="147"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="759"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="811"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="856"/>
            <end position="868"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="898" mass="99533" checksum="54C761729C42CD70" modified="2025-10-08" version="1">MDSVSMPVSARPGYPGEDGSVARYPGFDFDASGQHFVTPSAHTMSSGRDTLRSISANPHVNNSQIPSGYSALYGLPAPPMGLSMPPQSLHQQNVIPAHDLYATPRHSISSLRNDSVVSIYQPDDAHRNPVYRSNEFRQYRSRQEQRQDKEAAIWPPELENPFLDALLLIPIMGRKKYFMRHQQYGRNMLIGDYVWIAYSKDFNTSQLSDKNHMRRSRKQISSHIQVLKNFFKYHRYFHFFFPARDKESGKKTPGAAEIETVETISLKNNPVLVALSEGRFPEVRPNYDYFGSLLDQGKMVTVRPKACSMCVVSREISIGHDKVPRTADGKPLALENYPHLAQNLEGDGSRARRPEGTLLHEYTRVIGQKESDTAKELVSSWEKTAPAIVEKLNLPEPQHEAPLTIIEMSVSLELHRTTFHSSAWLNVLVEMLIESSALESHKWRSVTRLARPRELCANPSDPLTEEMTEEIGTQYVHHPDCGTTRVACDCVSHPRKEIKIPFPIDIWASMLQIATCHANRNREGDPRESEAAAEDLISQVVMVQELWSSACYPGHETRWNRQALIMWRFSGAFKPRGSASRHDVSPSTAWRFLTVNDPTSEYHQQQAYISADQAHAMSMPTNSITSPTSANISQAHNNMALGWPTAPIMRGIGSISSSSHGSLDTSSDVLSSALSGAPTPPPTAGLYHSGYDAHALSNSFISSGLSTQMDPHINASTGMVGDAAGAHAQYPYLASVTQSFNSSVCEPSLGAWDVTSSLETWPQQQPGNGGSASPYEPTIVGKSANAWQDDGHGDSQGFWPSESKAIWPAAVGQSGASCIPGQQWDTRGPWDGGNRTQSFDRESEAASPLTTLGKRRRDDGSEEDKKVPTDYQRISHKRASLRDSQQLILSESVQTDQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z283</accession>
    <name>A0ABR3Z283_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoglycerate mutase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003696</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000092">
        <property type="protein sequence ID" value="KAL1894314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="226" mass="25323" checksum="9B26CF1DE82CF428" modified="2025-10-08" version="1">MLVALSRPASLSASKLVAVSAAAPAPQHNPGFVEATKSKPTVYLIRHGEKPKEGNGLSAKGMQRAECLKNLFGKDSNYNIGHIMAQKPKKNGKRKRPYDTVKPLADHLDIEVDTSCPRGNMKCVKKAIKHYKGKGNILICWEHKRLTKIVKTLGLKHHAPHYPAKHFDMIWTDPPKYHKLDPITYESCPAIYESDDGNNDDGYDDDDVDDDDDYDGDEEVWIETVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2Q0</accession>
    <name>A0ABR3Z2Q0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cystathionine beta-synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000092">
        <property type="protein sequence ID" value="KAL1894313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42115">
        <property type="entry name" value="BETA-SYNTHASE (BETA-THIONASE), PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08420)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42115:SF1">
        <property type="entry name" value="BETA-SYNTHASE (BETA-THIONASE), PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08420)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="165" mass="18200" checksum="CB55612F76F4DCC6" modified="2025-10-08" version="1">MAAASTSVPATTAEPPKYVPRWSDRYRGATVEDLDPPAALSMTPEDSINSALLAAFEREYTHLTVVDSNTRGLLGYISIPQLQGALQAGKASPNSSLASAMVRFKRKARRYKVITMDTPLEELEEFFFGGAEKQEFAVVSDDKRRFVLGVATVEDLEKFVARRPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2Y9</accession>
    <name>A0ABR3Z2Y9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Isoaspartyl peptidase/L-asparaginase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_003904</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000100">
        <property type="protein sequence ID" value="KAL1893884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04701">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.30">
        <property type="entry name" value="(Glycosyl)asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000246">
        <property type="entry name" value="Peptidase_T2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188:SF43">
        <property type="entry name" value="ASPARAGINASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188">
        <property type="entry name" value="L-ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01112">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1893884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="503" mass="53850" checksum="E3991CDB4A628F07" modified="2025-10-08" version="1">MNEKMEYYAKPGGPVAGLAPRVIIQGGAGNITPTNMPEETYREYRSSLLDIICRTNKYMTTPCTATGVLPSALKTAVFAVSLLEDNALFNSGHGAVFTRDGINELEASVMVSRGFHKRTVGVLGLQHVRNPVKLAAAILEHGDIDLDPAQSARDNDSSVSTNADRLDIPSGQGHTMFHGATAEQLAADYNLDLVHSSYFFTQKRWDEHQRGLQRERLGSGSAHWSSKEYVPQGTCGAVAMDSTGMVCAATSTGGLTNKLTGRLGDTPTPGAGFWAEEWQDTPQLAAQALGLGEFTSAASAKIMPTGVSLSSALLHLLTDCLPTPFVYMPVASSEFFESPGLLPITISRSMGTSGTGNGDSFLRIAAGRTVGALARFRPLPTQSALSAVSGRGGALQQSAGDRFGRTGEGEGGMVGIESVVVRRGEQVVYTRTHIVQDHNCGGMFRAWIDDDGKAIVRVFNGEPELGDSIQAMEVRQEEVTQFSGVGDDNPWMRIRGYRSKDIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z302</accession>
    <name>A0ABR3Z302_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_003406</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000080">
        <property type="protein sequence ID" value="KAL1894991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1894991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="451" mass="50897" checksum="C2868CB37F284016" modified="2025-10-08" version="1">MNSSPIFQATSESTGSLFGSLDASDDESYDERLVLDYEFERFMNYPSIASESTEHVYDTLLRSPSIDGLLYLPKACKGLSKSLAYDNILGHARAVGKLAAHQDTSDWISSAHFRATNTTQGIESQAKEHMERYLSSISVMSQPSTFRWCDHVSMLKASMMKRAWEYCSRPAIDSIEKIVARLDHPLRNLHVDKIPLPNEKDFVNPIFFSQQLVTMLSVSDAPRTQIHMSSLEEVTQKPAFVLYGYSPDTYATHFSFGMTLDDTLQPTPVMPFLQVVFDSNPNEAVHCNLPIQHRMASPIRSVEGLNYSATFRSGNSIVPGDCFFTICIDSDNSKVRIYVSSRSDSSCMYSACLAGFIMPDRIAMQQLYILFRSIVEWGCLERLSLIAHNMGVEPTGVVLDYERFSYWLYKDTGPKIERAVFFPRPEWMSVGMLGDIMKNHWPEGSSGPMDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3D5</accession>
    <name>A0ABR3Z3D5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_003332</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000077">
        <property type="protein sequence ID" value="KAL1895149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1895149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="110" mass="12285" checksum="120A77A74F4ECB86" modified="2025-10-08" version="1">MARYNIAASNEYLAIMGMEMHSFLDYAMDLQAMTKEKLQFLLPVVFTVGPWVPQSHFGNDLPANEELEGSMVPARSQEYATAALYKHAVLLAENSAKHLNNAIAVEKKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3K4</accession>
    <name>A0ABR3Z3K4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Stress response protein NST1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NST1</name>
        <name evidence="10" type="ORF">Cpir12675_003385</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">May act as a negative regulator of salt tolerance.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the NST1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000079">
        <property type="protein sequence ID" value="KAL1895113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051195">
        <property type="entry name" value="Fungal_stress_NST1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025279">
        <property type="entry name" value="NST1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31780:SF10">
        <property type="entry name" value="LD36051P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31780">
        <property type="entry name" value="STRESS RESPONSE PROTEIN NST1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13945">
        <property type="entry name" value="NST1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="36"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="187"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="385"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="473"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="597"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="874"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1081"/>
            <end position="1116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="36"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="187"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="198"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="241"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="257"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="386"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="493"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="516"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="551"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="597"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="634"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="756"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="892"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1081"/>
            <end position="1090"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU049441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1895113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1337" mass="145287" checksum="7DAAD69465D4AC1D" modified="2025-10-08" version="1">MPASKTCLPAQNLSSMRNTARYTNKDGTKVITVPRSLSSTTSSVVPTDQSFALPSSSATTAATTVPSPSTLSVTVSHTGVSAPSLPESDPVMSNISTKKAKKRQRQAAAKAAAANGNNTSSFAAVESTFALGSSAEPNFLTATASGSKAFPTEKGTLISNASQNLDNHSQDRLVASQLIASSDYPIASATTTSSSQSKKNKKRKKKAKKESPAPENSVVEPQYYETRNSSVSDSHPYQQANHHHHQQASSHPHHSPLVRDDRVWDTKPHEDRERIKEFWLSLEEEERKSLVRLEKETVLKKMKDQQKNTCACNVCGRKRTAIERELEGLYDSYYRELEQYAQEGNATPFLTASTPNDLPIRRPPMPGAFPRTPGSQSRIIEHVNGEEFDEDEDDLDDDAEDDDAYSDEDYEEEYDDDASLDARVPPPRHQDDLMAFGNSLQVKEGILTVADDLLRNDGKRFIEMMEKLAERRMAREDSNYTSGHIPSEPRHTSNVPSVNPNVVLPLGADHDHTYEDVNEPYDDEGDEGDDGDNYDDEDAEVDEEDEEELDDPRSEEQRMAEGRKMFQIFAARMFEQRVLTAYKKKLSAERSARLMEELDAEERERQEREAAKSAKQQRKREKERAKKQAAAEAKAQREAEKAAEEAAKKAEKEAQAAKARAKAEEKKRAKEAQRRAEEEERQRKEAERLHRLHEQERKNKEAKERQNKLREEQKQKEKEAREAKGRELREKQEQKEQKEREEKEKQEVLARERKAAASAEQAKQALVAPASTAPLPPSATAPVAASTIIPASSALPVTPSKPKATLSGITPGKTLMAAVSRAPSVLGTPAAPPTSTRKASITSGLHNVLPMHNSNPGTTYVSPKIPAVTPIKAAKVPTPIRSRAPSQQMADNSSSSAPSGSQASGAPSQNASPLIGSSIHTSPSPLSSMAPHAPNLPPAVNNHFYNNQPLSPTNLGGLKAMLPTHAEQFMSRPSTVGAPPPGLPAPSMPPGLYNGRPVPDGMYSRFGSVDGISAPPGLGVPPMKTFPTPSAGLNNMPFDAFGGMSISNFNFGMSTDSNQPPSGHGRQASASFDFSALGITNSKNGSNSMSKPAPIGRPGSVVHGSRSNSMPHDDVNEHLGSRALLDDAQDDILGPSPAPRQRVVSGAPGPIRPAVFSASPFIDKSSTFSLGGYSQWGPTTPSSGFAPPAGIWNNPTTSSSATMPFPSSAGVSVASSHPWRKAVAPPTLRRYLAQACQTFREAGQLVHPDGYADYGKIKMHIETQLHTEIDDRDLMNVTETLGNTHNGNGTFECRELGGGVRVIRWDPPVDPFLGSLQKPAVSRDSVDHVIGHGIGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3W1</accession>
    <name>A0ABR3Z3W1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Defect at low temperature protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">DLT1</name>
        <name evidence="9" type="ORF">Cpir12675_003410</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Required for growth under high-pressure and low-temperature conditions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DLT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000080">
        <property type="protein sequence ID" value="KAL1894995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038869">
        <property type="entry name" value="DLT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40021">
        <property type="entry name" value="DEFECT AT LOW TEMPERATURE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40021:SF1">
        <property type="entry name" value="DEFECT AT LOW TEMPERATURE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="54"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="325"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="363"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="333"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="367"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="385" mass="42086" checksum="C17E0754C3FDEE0A" modified="2025-10-08" version="1">MAFVYLTRLYINKTALSAIPKSWLPIQKGDVRLPVWKMINSYLSRSAAIAFASRPRPKREAGDSTAHLPESISASFTPKHESAEDRRITMQRTPSDSPFLNNHRAILEIPFSSAAIWDNIEHPGWSSPNSPEMPDVQYSVVYGEIPNLIEAKAFTLAQTGPNSGSTPSVLHSSLEEVLARPFNMSLRDYITHLSNYNVISQSTTVSSFLTNYERAKYSTRPLPGAEFREMMAQFAQILQSMQPLDLTSPENASLFGYDDDNTSLHSSLAFGSRSFHYASNSGERSLGSEPSIRSSVSASPSFRAYFGSSPPSRSGSIGAASYLTAPATPQKRSQSIADSSSIESLSPSLYSLRASRMTSPASKHLRSSYLSSSGSVVHKATIPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4F6</accession>
    <name>A0ABR3Z4F6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Obg-like ATPase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">OLA1</name>
        <name evidence="6" type="ORF">Cpir12675_003394</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000079">
        <property type="protein sequence ID" value="KAL1895122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04867">
        <property type="entry name" value="TGS_YchF_OLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01900">
        <property type="entry name" value="YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.300">
        <property type="entry name" value="TGS-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00944">
        <property type="entry name" value="YchF_OLA1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004396">
        <property type="entry name" value="ATPase_YchF/OLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023192">
        <property type="entry name" value="TGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013029">
        <property type="entry name" value="YchF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041706">
        <property type="entry name" value="YchF_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00092">
        <property type="entry name" value="redox-regulated ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305">
        <property type="entry name" value="OBG GTPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305:SF11">
        <property type="entry name" value="OBG-LIKE ATPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06071">
        <property type="entry name" value="YchF-GTPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006641">
        <property type="entry name" value="CHP00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="4">
        <location>
            <begin position="21"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="5">
        <location>
            <begin position="306"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="30"/>
            <end position="35"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1895122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="394" mass="43837" checksum="5E5919E7365A6146" modified="2025-10-08" version="1">MAPKKPVVEEKILLGRPGNNLKSGIVGLANVGKSTLFQAITKSNLGNPANFPYATIEPEEARVVVPDERYDWLCEKYKPKSRVPANLTLYDIAGLTRGASTGAGLGNSFLSHIRAVDAIFQVVRCFDDAEIIHVEGDVNPIRDLEIISDELRLKDIEFVEKALENQKKKTRIGGQSLEQKKAKQEQETIEKIHKYLVDGNEVRKGTWGPKEIEVINPLMLLTAKPVVYLVNLSERDYIRKKNKHLPKIAEWLKANAPGDPIIPISVSYEERLTRYETEEESLAEQKAVGAESALPKLIVLMRKALNLGSFFTVGPDEVRQWTVRNGIKAPQAAGVIHTDFEKTFIQAVVFNFAVLKEYGDEAEVRSKGKVMTKGKDYTIEDGDIVLFKAGAAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4T0</accession>
    <name>A0ABR3Z4T0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_003503</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000084">
        <property type="protein sequence ID" value="KAL1894808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF124">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="53"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1894808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="271" mass="30775" checksum="40A6C19D00A0CA14" modified="2025-10-08" version="1">MSSLPVINGTEVVTEPPPGYICDFDNPKQKNAVAAYWIVAVFGFLSTLFCGQRLYVNAVVRKRLWWDDLLVILGFVSSWIIQIFILEGFVHKYIGTHLWEISADKFYTFCKWATYVNPILYVYPTVFCKVALQMFYLQLGNMSFRYKAAIYMLIFATVGSGIGILFSSIFICSPIRKGWDFRITSGSCIDRPAMYQATAGIGMATDVLIFAIPIPMVMRLQMSRRHRVGLIFLFFVGSITVITSIVRLVLLVTSLYEDDLPWSAGLITIWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4V6</accession>
    <name>A0ABR3Z4V6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YAP1-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">YBP1</name>
        <name evidence="2" type="ORF">Cpir12675_003318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000076">
        <property type="protein sequence ID" value="KAL1895301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013877">
        <property type="entry name" value="YAP-bd/ALF4/Glomulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040347">
        <property type="entry name" value="YBP1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28020">
        <property type="entry name" value="YAP1-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28020:SF1">
        <property type="entry name" value="YAP1-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08568">
        <property type="entry name" value="Kinetochor_Ybp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="653" mass="72283" checksum="B294D60C681153F6" modified="2025-10-08" version="1">MINNNPPAVPIDETAAAVERLLESRPPATDTFTYLTIIEKSLCPEILPTLLEILQDAAICQDIGWDLVDKLLIMPGSADCLQTIARLGNPREVIIKVLESLERLGDGSLEKIHDSEDNDDGNYSEEASAEIRSIDEKTNRDKTNAHFSVFLGMLGILHKRLDVRSPSRFLHSSLATVCKVYSSNPSPRATAAIIDLVYALQPGATRPPLPNRQSSTVLAQAFPTAKGRVTAPDPEADTPAVNKQANDRVEEELKSRLLRTFVSCVIEAYVNGNDMAWAARLNEYYVPEKIVPGRRTWMQAFKEDPELVARDGQIGQLVSLAADLGLTELNVDQVKDLCESPLQIFPLRSEPDPQDPEAIKLSSGGMICLSAYWTFASEVFDATYKTPDLYIFPEHYKLLGRFLATDADACISANPGTLEALIVIGLYLESNKKVTAAKITTKPNFMEYLHLVTLVSVFHPSLLVRNAATVLAGAILHADPDDVDRLKILEDLLENCIFSSLQAQAVTWLREELQVGLPHAIERAEMPLSPVKPASSRFSSTEALDTLQYVLFPRLEYLKGMTDAELLDCWTQNYPLHLQAVNLAVLMFGTKENETSLYSVLVPLTMPEAVEQRYLLPLGEAARKVMALGKEKNLVELEVQASLLLDRLDKVHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z578</accession>
    <name>A0ABR3Z578_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Alpha-taxilin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003064</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the taxilin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000067">
        <property type="protein sequence ID" value="KAL1895786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026183">
        <property type="entry name" value="Taxilin_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16127:SF13">
        <property type="entry name" value="GH01188P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16127">
        <property type="entry name" value="TAXILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09728">
        <property type="entry name" value="Taxilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="306"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="388"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="444"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="455" mass="52160" checksum="A80930A807BCDDB8" modified="2025-10-08" version="1">MSSTNGYDAGSATRKGKNKKPIDPNDSTSRLLEAKINQLEREAASDKDQEAEIEREVKRANRDLVQQISKLDELHKIDLLLRRASELMADLRRMEKENMKNKKRGDALQKDKDAKMTELGRTNQLKEKLEKLCRELQKDNNKLKNENKTLQDNLARTTKAHDLRMESVLGKLEGYQKEKDNPRQEVIDVSMEELFRQRFKTLIEQYELRDLHFQAQLRTKELEVQYNMVRFEAQKRIAEDEVAKGRQLQSQVQGLSSSDAELRSQVNRYAEKFKQVEDTLTNSNELFSTFRKEIEDMSKRNRVLERENKNLKRKQRVSDESLIQMAGEREDWRAQASSSKHKTGSGPESASHPNVNGIEICPSDQTNGSRNGEGHSHHHHHHHHEPDENSEDSTVDNSDDGYHTSDAESDTMDYPGMTNTSPPAQCASERPTYGPERPPGLSTAPRNTPLSASKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5X2</accession>
    <name>A0ABR3Z5X2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Neutral ceramidase</fullName>
            <ecNumber evidence="3">3.5.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_002932</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>an N-acylsphing-4-enine + H2O = sphing-4-enine + a fatty acid</text>
            <dbReference type="Rhea" id="RHEA:20856"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:52639"/>
            <dbReference type="ChEBI" id="CHEBI:57756"/>
            <dbReference type="EC" id="3.5.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the neutral ceramidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.23" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000063">
        <property type="protein sequence ID" value="KAL1896019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2300">
        <property type="entry name" value="Neutral/alkaline non-lysosomal ceramidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006823">
        <property type="entry name" value="Ceramidase_alk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038445">
        <property type="entry name" value="NCDase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031331">
        <property type="entry name" value="NEUT/ALK_ceramidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031329">
        <property type="entry name" value="NEUT/ALK_ceramidase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12670">
        <property type="entry name" value="CERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12670:SF20">
        <property type="entry name" value="NEUTRAL CERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04734">
        <property type="entry name" value="Ceramidase_alk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17048">
        <property type="entry name" value="Ceramidse_alk_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0746">Sphingolipid metabolism</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046382053" description="Neutral ceramidase" evidence="5">
        <location>
            <begin position="35"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="domain" description="Neutral/alkaline non-lysosomal ceramidase N-terminal" evidence="6">
        <location>
            <begin position="51"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="domain" description="Neutral/alkaline non-lysosomal ceramidase C-terminal" evidence="7">
        <location>
            <begin position="578"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="589"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1896019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="741" mass="81337" checksum="18973C0F3B310123" modified="2025-10-08" version="1">MALSSVPGQRPHSLFLNLSLTLLLISLLISPIAAFSIPRNTDYNYGTGDKYLIGAGRGDITGPVVEINMAGYADLAQTGTGLRQRIYSRAFIFGDVSKPEDRVVYVVLDTQSGDTAIRNGILEGLAKLGDEYKIYSRHNVAITSTHSHAGVGGYYNYLLPQVTSLGFEKQNYQAIVDGAVLSIKRAHENLTTGYLDMATTEIEEGGINRSLWSYMHNPQEEQDLYNSPVEKTMWVLRLTRESDRKSLGVVSWYATHGTSLLQNNTHIAGDNKGVAAYLFEKDMENDENAAEGFVAAFSQSAMGDISPNTLGSWCDDGSGQQCSFENSTCSDGRSQSCRSRGPMFDKLDLGVSSCFEIGRRQFAGAKAAWDSMTTSSTKIVGSTVKAYHFFHDMRYAEFTNQKGDIVKTCPGALGYSFAAGTTDGPGFADFTQNDSGEPDANPFWKIVSGALKNPSDEQKKCQEPKPILLDIGEIDFPYAWGANLIDMQSLRVGQLIIMVGSGEITTMSGRRWRKAVAEAAAKQDITQGVEPIVLNSGPSNTYSHYVTTPEEYDVQRYEGASTLFGRNTLDAYINLTLSSLHYLAPDSTDLPESGKLPPDNRDDSLSLTSGVVRDDEPKDTSFGDCLIQPQMKISPGGVANATFVGANPRNNLRLEGTFAAVEMKQGNTWTQVRSDYDWHLVYSWKRTNTLFGHSEVVITWELEEDTAPGTYRLVYYGDSKGLFSDDTTPFEGRSDEFQVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6H0</accession>
    <name>A0ABR3Z6H0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003386</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000079">
        <property type="protein sequence ID" value="KAL1895114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046499543" evidence="3">
        <location>
            <begin position="22"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="208"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1895114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="278" mass="29630" checksum="7495184CCB8FBB2C" modified="2025-10-08" version="1">MTRPSIFILAALFSPIYTVAAATVSRISCSDAASVVNARSSIITCTDDSVDACLARLDSIGSDSVVQECFSSSSCASVVNGSVIDPSLTCYLYTMTDDAPESNGAELRMRRRRPSPPRSTDGSLAALTTSSPPESTSGIEMGYLLLARDTLSYDANCSSLTSFKSKVCTTESDTSSCSSTTITTAECMDGYLCKTGGCMELRNSMDTAGIIVAICFASFIAISAGLICFYCCRERSYEKKMAARAEAEAIAKAAAMDRKKADRQPLMSDQNNPFQDQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6M2</accession>
    <name>A0ABR3Z6M2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NineTeen Complex (NTC) component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ISY1</name>
        <name evidence="7" type="ORF">Cpir12675_003010</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ISY1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000065">
        <property type="protein sequence ID" value="KAL1895970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.660">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029012">
        <property type="entry name" value="Helix_hairpin_bin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009360">
        <property type="entry name" value="Isy1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037200">
        <property type="entry name" value="Isy1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13021">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR ISY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06246">
        <property type="entry name" value="Isy1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140102">
        <property type="entry name" value="ISY1 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="189"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="67"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="248" mass="28307" checksum="8D83CCC4565ECA24" modified="2025-10-08" version="1">MARNAEKAQSMLFRFREAQAAEIGIIDAGRTRRPKAITEVDSIPSAEKWRGQVLKEISRKVSRIQEISQSDYQIRDLNDEINKLMREKHMWEVQIRNLGGPNYMQRAAKIYDDNGREIPGTGKGYRYFGRARELPGVKEMLEAAARKPEPSGTTGRNDLRRVPVDAAYYGYAPDEEDEDLLAWEAQREREALERMADGGSGSEPPPGWEPLPGDSGDGHGWVLPTLEEVQQELMDRRKQRLLKQLDKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7S7</accession>
    <name>A0ABR3Z7S7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002669</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000054">
        <property type="protein sequence ID" value="KAL1896721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="643"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="671"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="745"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="823"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="848"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="360"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="931" mass="97996" checksum="0DE35AC15E65B3DA" modified="2025-10-08" version="1">MVRLSNFDGLSVNSEWRSPPSSVSSSPRSSPVGGSPAEGRVRSPCQGSVADSIRTARAVLDRRSASPVGSPPGRPSFPLAPVAGPSRTLDPRRVRSAMGPKAAPFVAGLAHRVSSFPRIQPGLKSAMRPAHIALDQRPSKAVRWAFDVKDNAPLPAEKVEEEPKDLGFDLDALADAVKELMAAESLGLADALSKILAELMVSDEGDEEDDQSSETSESSSNLEEPYVPFWRPARYYKRTSIRQRSGSASPPRSSERPDPVRRVFSDTGSRDRDFFPVASALPDAEEGSAIFSASPIVRPQSTMPSHLDGSGPSSSLSFAPLGLPSFSPLVLSPSELSSPFGELSLGQFQDFSSLPGPAMSQAYGSSGSQASETGSSSAPSSPEVPSSPFAWTPLGSTYSHSLPSDVETSFASPAPLDSLPTIEAHPISGGVSSFVASSPSVPSSLERPFSAGGLLAVEFSPPSLPSLPVQEDAAISPAPLSPAAPSSPFVWTPPGVDYSRFRCPVAEATPLPLSSSTGSSPVEASTSVAAVSLESTSPLSSSSWPSPRELWEELYARSPSLISRAGSDASAPMEWSSLPALPSRDFSRITGGGSGLPRAWHSAKTSEVFVAPAVLPGSFPESPASGSSFGSPSRLSPLEAKPMGLFMGLLCGFWLAANLIFVSLVGPLAKLLFAFSGPVLVLLGALVFPASSWAVFSAFGLAFGGMDSMLQILVSWCRGALSWFRSLLLAVPWPVERSWRGVVEVAATLVGGVLVVFCLVCAEAFAWGCLLARVGWRAIRPRLADTVCSNWSSMVSVFCCLQSRFREEMAAATSTLNGTMRRAALASLTLVCSVAETVVAYLQSSIVFLVLLLWKSLVSVVFSSVSPLVSSLARFYLVPPEPVNTESLAVSSSLPLGPQPAPRRLTNFQAAGIHRIPPGWETPFSGVPHRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7Y1</accession>
    <name>A0ABR3Z7Y1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transmembrane protein 53</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002657</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000054">
        <property type="protein sequence ID" value="KAL1896709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008547">
        <property type="entry name" value="DUF829_TMEM53"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12265:SF14">
        <property type="entry name" value="INDOLE-DITERPENE BIOSYNTHESIS PROTEIN PAXU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12265">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05705">
        <property type="entry name" value="DUF829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1896709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="304" mass="34107" checksum="82B62493A85E9BF0" modified="2025-10-08" version="1">MSTQTLVNTTPAKPKLETFLGFTRITDQIYVHKPQAIRASITPTSGPRVIIIYGWGDGLPRHVSKYTDGFRTLFPNAIIIAVLSPIFKALTQSLTARSQNMGQLLDIAYPVDATYTASSPEDAVLVHAMSNTGAINYTATIHAYQQRFGRPMPCRLLCHDSMPGSVKLTWENMPRWSRAMALGTAAFFPWPFFATQGIWGLFLAVNEFGHWIAGAETAPVTAARLTVDEEFTDKNMVKLFMYSKEDEIIYWEDVEAAMAHSLQKGYTVESEIFTGSGHVGHMRQSPEKYWKLIQETWEKTTKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8T2</accession>
    <name>A0ABR3Z8T2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_002879</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000061">
        <property type="protein sequence ID" value="KAL1896233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052427">
        <property type="entry name" value="Glycosyltrans_GT2/GT47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47844:SF1">
        <property type="entry name" value="EXOSTOSIN-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47844">
        <property type="entry name" value="SYNTHASE CPS1, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G02500)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13641">
        <property type="entry name" value="Glyco_tranf_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="297"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="332"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="369"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1896233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="442" mass="49909" checksum="9EAD2705B92BC415" modified="2025-10-08" version="1">MIHQLAYTFLSRPCPIPANPTYRASDATIIVPTVDPLNVDFAECIRTTLEAGPGEMIVVTVGKGLLASLTQAMEKYRACFPSTKIRVCAIDEANKRKQISAVIASISTKITVLVDDHVFWPSRSFLTAIVAPFEDPRIGGVATIKKVRRTAPGHFNFAAFWNMLGAIYLERHNFEIQSTNAIDGGVFVISGRTCVYRTQIFQNESFQHNFTEEMFFLGKYGPLNADDDNFITREIVKAGWKIKVQNHPDARIVTTVGTYPKFLSQCLRWARTTWRSNPASMFTDDRSCWWRTPWTSWAVFVYTLFNFSLVIDLTLVFGLAQTTWYTDADSSTRVSMLVGLVLWIAAFKAQKLAAYFGDHPRDIVMFPLYILWAYYHSFIKLYSMFTFFDVVWGGRDLSKVSNNSKDATLAATTVTSDRVQGIRGTPISDCPCGMDSDDDEEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9P7</accession>
    <name>A0ABR3Z9P7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein mago nashi</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MNH1</name>
        <name evidence="4" type="ORF">Cpir12675_002558</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mago nashi family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000051">
        <property type="protein sequence ID" value="KAL1896977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11295">
        <property type="entry name" value="Mago_nashi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1560.10">
        <property type="entry name" value="Mago nashi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004023">
        <property type="entry name" value="Mago_nashi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036605">
        <property type="entry name" value="Mago_nashi_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12638:SF0">
        <property type="entry name" value="MAGO HOMOLOG, EXON JUNCTION COMPLEX SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12638">
        <property type="entry name" value="PROTEIN MAGO NASHI HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02792">
        <property type="entry name" value="Mago_nashi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89817">
        <property type="entry name" value="Mago nashi protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="148" mass="16984" checksum="F60575C25F289D01" modified="2025-10-08" version="1">MDWILSSGHSGRFGHEFLEFDIRVVGDGSSAVARYANNSNYRNDSLIRKELYLSSLVVEEFKRIVKTSEIMKEDDSKWPQRNKDGRQELEIRLGNDHISFETAKIGALIDVSESEDPEGLRVFYYLVQDLKALVFSLTALHFKIKPIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9Z2</accession>
    <name>A0ABR3Z9Z2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002749</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000056">
        <property type="protein sequence ID" value="KAL1896653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045794404" evidence="2">
        <location>
            <begin position="20"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="334"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="527"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="547"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="575"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="607"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="650" mass="69200" checksum="B64170CB8C7243F3" modified="2025-10-08" version="1">MKFLRTVLPVVGVASAVNAAALPGGNIKRDDLELSGSGQDEYKQPGYPHPYGNGYEVEETTVTEHVTHTKTTTAYNTVTTTAAGADAERTVTVGETVTATAPGYEAEHTITVAETVTTTAPGYEAEHTVTVSGTETVTSIVSGYEAEHTITVAETVTDTAPGYDAEHTVTVTDHAGKQTETITTSVIVPATVTEAITVPATVTATAAGSYETSILTTYITVAPSPSYSPCHSERTIALTTVVTVPWGGWGDSKHKPTNRPYHNYAGSSSPSGMVYASRTGTAASAPSPDSDGSIDVSFANSLENAALSASLSRASDAPIAMLNGSGSSQNARHPTTLSTTTRPSFTPSSSVDTPASAHRLAVRGHKGGYGASPEPAPMNEEPCESEPIEEPCESESEPEPCQPDHDDQSWEPSKPEPCESENPSKPEPCESEKPSKPEPCESEKPSKPEPCESSEKPGKPEPCESEKSSKPEPCESEKAHKPEPCESEKSPKPQTYEPESPYKPDTYQPAPYGSEEPVKPYKPQPCESEKPSKPEPCDDESSKSDPCDPEPCESGEPDPCEEPKKEDKKHKWWKGKGDKKKEGKKDKGKKKGLKEKMKDKMKGKKGGKNDDKKDKYGEKPTPVKGAASALTFNIRWAATLVIAGVIATVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA76</accession>
    <name>A0ABR3ZA76_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 10">Ribonucleoside-diphosphate reductase</fullName>
            <ecNumber evidence="2 10">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">RNR1</name>
        <name evidence="13" type="ORF">Cpir12675_002284</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 10">Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + [thioredoxin]-disulfide + H2O = a ribonucleoside 5'-diphosphate + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:23252"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="EC" id="1.17.4.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the ribonucleoside diphosphate reductase large chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="2 10"/>
    <dbReference type="EMBL" id="JAWDJO010000043">
        <property type="protein sequence ID" value="KAL1897556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01679">
        <property type="entry name" value="RNR_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013346">
        <property type="entry name" value="NrdE_NrdA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000788">
        <property type="entry name" value="RNR_lg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013509">
        <property type="entry name" value="RNR_lsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008926">
        <property type="entry name" value="RNR_R1-su_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039718">
        <property type="entry name" value="Rrm1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02506">
        <property type="entry name" value="NrdE_NrdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11573">
        <property type="entry name" value="RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11573:SF6">
        <property type="entry name" value="RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02867">
        <property type="entry name" value="Ribonuc_red_lgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00317">
        <property type="entry name" value="Ribonuc_red_lgN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01183">
        <property type="entry name" value="RIBORDTASEM1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51998">
        <property type="entry name" value="PFL-like glycyl radical enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48168">
        <property type="entry name" value="R1 subunit of ribonucleotide reductase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00089">
        <property type="entry name" value="RIBORED_LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-0215">Deoxyribonucleotide synthesis</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-cone" evidence="12">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="768"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="818"/>
            <end position="865"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1897556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="888" mass="99436" checksum="7F9F095623EB4DB8" modified="2025-10-08" version="1">MFVQKRDGRKERVQFDKITARVSRLCYGLDMDHVDPVAITQKVISGVYGGVTTAQLDDLAAETAAYMTVTHPDYAILAARIAVSNLHKQTKKQWSSVVSDLYHYVNPANRKASPMISKETYECIMRHKDELDSAIVYDRDFNYQYFGFKTLERSYLLKLDGKIVERPQHMIMRVAVGIWGDNVERVLETYNLMSSKFFTHASPTLFNAGTPQAQLSSCFLVDMKDDSIDGIYDTLKTCAMISKMAGGIGLNVHRIRATGSYIAGTNGTSNGIVPMLRVFNNTARYVDQGGNKRPGAFAIYLEPWHADVFDFLDLRKNHGKEEVRARDLFLALWICDLFMKRVEKNEDWTLMCPNECPGLADCYGEEFEALYEKYEKEGRGRMVVKAQKLWYAILEAQTETGNPFMLYKDHCNRKSNQKNLGTIRSSNLCTEIIEYCAPDEVAVCNLASLALPSFVDYNKGEYDFKKLHEVTQVVVRNLNRIIDVNHYPVQEAHNSNMRHRPIGVGVQGLADAFLALRMPFESPEARQLNKQIFETIYHAALTASMEIAQTEGTYSTYEGSPVSQGILQFDMWDVTPSDLWDWTSLKEKIKQHGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYQRRVLAGEFQVVNPWLLRDLVDLGLWSDNMKNRIIADNGSIQNISSIPADIKALYKTVWEISQRTVVQMAADRGAFIDQSQSLNIHMKDPTMGKITSMHFAGWKLGLKTGMYYLRTQAAAAPIQFTVDQEALAASENNGVQEKALSGLKRRAPPSGTSYMSSMLPRSEDAATGSPVFNASTARPLTTKTLAVAEHEDSSPKALPTEPTAETAEVPDASLEKKAETQEEDAANDSKDREGNIYSDAVLECSIANPESCVMCSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAG5</accession>
    <name>A0ABR3ZAG5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Inositol polyphosphate-related phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002396</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000046">
        <property type="protein sequence ID" value="KAL1897292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046985">
        <property type="entry name" value="IP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200:SF286">
        <property type="entry name" value="5-PHOSPHATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G07600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200">
        <property type="entry name" value="INOSITOL 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00128">
        <property type="entry name" value="IPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inositol polyphosphate-related phosphatase" evidence="2">
        <location>
            <begin position="53"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="497"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="598" mass="64674" checksum="0D7C3BFFFC2E30D3" modified="2025-10-08" version="1">MAVPVSGISVGTSATSSESSPHLPPQPTFSPSTATSASTSVLQHSATSSPKNMKLDLLMLTFNCAKAAIDVGTFATHLYSALVECEGAMVPAQLPELVVLSLQEVAPLPNAFIGGALLDLYLRHFEEALNLAALNATKCTSTAACNNTNASAKVATASNVALDPTALTSVSGHRLYSLVKSHNVGMTAIMILARSPAALGPVQVAEVGFGAAGMGNKGAVGLRTVFTRDGSNGSSSESTELTFIAAHLAAMESNLEQRNTHWLRIMRELTFDDPARIFEEYNQTTAHSASEKGQQGQGRDTDLGSENIGLLAARHRRSKANLNARLHELSVFKPSSHLFIGGDLNYRISSTPPPPNAAFPSPNPASPHYFEKFLPLDQLTQERKAGRTLHGMTEAPVSFPPTYKYKALARIVPDDQIETHVPAVFAQHRYPSWTDRILYLDTPPWLRNSGDADGDKEAQSTSIDVHKYMSLPLMRSSDHQPVYLRVSVPLISRSLMTPSPMPGVRSSGFEQNHESDGDSDDDSAPELPDQWRSDPRAFMPVSIDANSWLLRRQGRRREWAVGWAGAVWSTRQGALVLATALSLVAATYLAVQNFYEFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAY5</accession>
    <name>A0ABR3ZAY5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycogen debranching enzyme</fullName>
            <ecNumber evidence="5">2.4.1.25</ecNumber>
            <ecNumber evidence="6">3.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Glycogen debrancher</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="primary">GDB1</name>
        <name evidence="22" type="ORF">Cpir12675_002171</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>Hydrolysis of (1-&gt;6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin.</text>
            <dbReference type="EC" id="3.2.1.33"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1-&gt;4)-alpha-D-glucan.</text>
            <dbReference type="EC" id="2.4.1.25"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the glycogen debranching enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.25" evidence="5"/>
    <dbReference type="EC" id="3.2.1.33" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000039">
        <property type="protein sequence ID" value="KAL1897826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11327">
        <property type="entry name" value="AmyAc_Glg_debranch_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010401">
        <property type="entry name" value="AGL/Gdb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032788">
        <property type="entry name" value="AGL_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029436">
        <property type="entry name" value="AGL_euk_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032792">
        <property type="entry name" value="AGL_glucanoTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032790">
        <property type="entry name" value="GDE_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006421">
        <property type="entry name" value="Glycogen_debranch_met"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01531">
        <property type="entry name" value="glyc_debranch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10569">
        <property type="entry name" value="GLYCOGEN DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10569:SF2">
        <property type="entry name" value="GLYCOGEN DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06202">
        <property type="entry name" value="GDE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14701">
        <property type="entry name" value="hDGE_amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14702">
        <property type="entry name" value="hGDE_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14699">
        <property type="entry name" value="hGDE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Eukaryotic glycogen debranching enzyme N-terminal" evidence="19">
        <location>
            <begin position="41"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Glycogen debranching enzyme glucanotransferase" evidence="20">
        <location>
            <begin position="146"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="domain" description="Glycogen debranching enzyme central" evidence="21">
        <location>
            <begin position="760"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="domain" description="Glycogen debranching enzyme C-terminal" evidence="18">
        <location>
            <begin position="1077"/>
            <end position="1549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="645"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00020723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00025780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00031477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF06202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF14699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF14701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF14702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAL1897826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1571" mass="175831" checksum="E9BC99EA52FCAC4F" modified="2025-10-08" version="1">MTPSAICSSEIYLLPLNDDGSPDIAGQYVYLAPRSPEPFVVRFSLEGTSSVCRYGSLWVNIPENGEDFKREKFREFKLVPNFSRNIEIDITIPHAGAYAYYITYAGLPPLAEVLELNDTSEPEVATHKTDLFYIDVAPYLTINSSPLPLDGLSVFTVLSKFMGKYPKDWSSHFHGISERGYNMLHFTPLQVRGSSNSPYSLFDQLAWDSQFFPNGESDIAKLVDDLEKNYGLLSLTDVVLNHTAHNSKWLEEHPEAGYNLTTAPWMESAYILDTKLLQLSSKLTEKALPTVLNDEKDLLKIMDAIKTDVIFDMRLWEFYTLDIEANATAAVAAWKSEKYSFPEEKDIEIIEKPLKEQAKYLTDNGLSGNDRMGSRFRRHIDPEISGGLLALHFGRFESDSTNGADEGAAKTKISTILDAVNLPFYKEYDAEVADILQQLFSRIKYMRLEENGPKLGEITAENPLIETYFTRLPKNEKTAQHSEDDLALANNGWVWGGNALIDNAGPNSRAYLRREVIVWGDCVKLRYGSSPEDSPYLWDRMTKYVRLLTKYFAGLRIDNCHSTPIHVAEHILDEARRIRPNVYVVAELFSGSEETDYVFVKRLGLSSLIREAMQAWSTGELSRLVHRHGGRPIGSFERDEITRTDAKTADGAKSIESTSEHTRNNLTTKSRELIRNIKSVPVQALFMDCTHDNETPFQKRDARDTLPNAALVSMCASASGSVMGYDEIYPKIIDLVGETRLYVSEASSSPSVKIGAGKNGIAGVKKLLNQIHTIMGKDGYDETHVHHEDQYVTVHRVHPKSRKGYFLIAHTAFPGYGNGNGAFNPVHLTGTKAKHIGSWMLEVDTSEEALAQVLNDKTYLNGLPSQVVDLSSVKLEGVGNDTFITVHDKFPPGSIALFETWIPSVEHSAGLDTYVTSEAAGAFNGLDLVDLNFVLYRCEAEERSTSNDQDGNYDIPGYGKITYAGLQGWWSLIEGIVRDNNLSHPLCQNLRDGLWALDSTIGRLERRSKTPGCERLAKPAKWLKERFDALHDIPSFLIPRYFALVIGTAYRASWDRAMSLMSPGVHEGQWFIQSLAMVSVQQTGIVPSASLYPKTQVPSLAAGLPHFAVEWARCWGRDVMISLRGLYLGTGRFDEAKEHIKAFGSVMKHGMIPNLLGSGGNPRYNARDSIWFFLQCIQEYTKIVPDGISILDEKVKRRFLPYDDTWFAVDDSRAYSNESTIAEIIQEALQRHAAGISFREANAGAAIDSQMSDEGFNIDIKVDWENGFIFGGNQHNCGTWMDKMGESVKARSKGVPGTPRDGAAVEITGMLYSTLKWVSELNAAGKFAKPGVEKADGSEISFADWAALVKTNFERCYFVPKDSVDDSKYDVNPSMINRRGIYKDLYRSGKEYEDYQLRPNFPIAMCVAPDLFEPAHALSALFVAESVLRGPTGMATLDPTDINYRPYYINSEDSTDFATAKGRNYHQGPEWLWPTGFFLRALLKFDLMRRGGGATARTESFQQITKRLIGCKKMIRESPWAGLAELTQKNGEFCGDSCPTQAWSASCLIDLYMDAAMEHHSHDLSIPIHRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB34</accession>
    <name>A0ABR3ZB34_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 16">Non-structural maintenance of chromosomes element 1 homolog</fullName>
            <ecNumber evidence="4 16">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Cpir12675_002312</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="16">Component of the Smc5-Smc6 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 16">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 16">Belongs to the NSE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4 16"/>
    <dbReference type="EMBL" id="JAWDJO010000044">
        <property type="protein sequence ID" value="KAL1897524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16493">
        <property type="entry name" value="RING-CH-C4HC3_NSE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011513">
        <property type="entry name" value="Nse1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014857">
        <property type="entry name" value="Nse1_RING_C4HC3-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20973">
        <property type="entry name" value="NON-SMC ELEMENT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20973:SF0">
        <property type="entry name" value="NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07574">
        <property type="entry name" value="SMC_Nse1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08746">
        <property type="entry name" value="zf-RING-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 16" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12 16" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="13 16" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14 16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="10 16" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="11 16" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 15 16" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="18">
        <location>
            <begin position="207"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="274"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="129"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU368018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1897524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="318" mass="35954" checksum="1E15CB3492B38E2F" modified="2025-10-08" version="1">MSRGSFAESDAKLFISKLLTTTGQDFEPEDVQSVLANLVTEARSKIAEFDYSIRIAIDQMTQERTYCFINIASDPATQLATLYSPDELSFIRRLLDAIFAKYNSPRMEVMAITKEQCLPLGRPAGSRPTGATQNDDVSASQAVDRGISHSDINRIMQELVNANWLAHSTAGFYSLSTRGLAELQSWLEDTFNDSEQEQGIWQRIKTCMACREILTQGLRCTNLDCLVRFHERCATTFFGSRRTHECPTCNTAWTGSHYVGEKAITQGRLYQQQQQQRNGRERRSNIVEDVFQQQNGASDDDVIEEGLEEAEEVDEMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB65</accession>
    <name>A0ABR3ZB65_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA pol II transcription cofactor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PRN1</name>
        <name evidence="6" type="ORF">Cpir12675_002282</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the pirin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000043">
        <property type="protein sequence ID" value="KAL1897554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02247">
        <property type="entry name" value="cupin_pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02909">
        <property type="entry name" value="cupin_pirin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008778">
        <property type="entry name" value="Pirin_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903:SF8">
        <property type="entry name" value="PIRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903">
        <property type="entry name" value="PIRIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05726">
        <property type="entry name" value="Pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045241673" evidence="3">
        <location>
            <begin position="24"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin N-terminal" evidence="4">
        <location>
            <begin position="91"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin C-terminal" evidence="5">
        <location>
            <begin position="246"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1897554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="371" mass="40774" checksum="760C359269DB70A6" modified="2025-10-08" version="1">MKFTLSIITLSVALLAATYRTSYQNIVACWIQSFARQLDITYSSALCPSTDSLISTIPSHPPIHLSSPEMSIPRAIRKIFLAAEQAEGMGAKVRRSVGTANLRNFSPFLMLDHFSIKPGAGFPDHPHRGQETITYLLEGAVDHEDFAGNAGTIHSGDLQFMTAGRGIVHAEMPAQNKDGSANVGLQLWVDLPAKLKNCEPRYRDLRAKEIPTGTFDDGRIVVKVISGQSNGIDSVKDLAYTPVWILDFTVKPGGKMSQALPEGWNAFAYVLDGKATFGAGEDKKVVDMYHNVVFEQAGDTVEFAVDEVAEKECRFVIIAGLPLDQSIVQYGPFVVSSQEDVYKALLDYQTFSNGFERARDWESQIGKTMKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBH3</accession>
    <name>A0ABR3ZBH3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ATP-dependent RNA helicase ROK1</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP-dependent RNA helicase rok1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">ROK1</name>
        <name evidence="16" type="ORF">Cpir12675_002115</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Interacts with the U3 snoRNA and is associated with the 90S and 40S pre-ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000038">
        <property type="protein sequence ID" value="KAL1898028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17957">
        <property type="entry name" value="DEADc_DDX52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044764">
        <property type="entry name" value="DDX52/Rok1_DEADc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF15">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="249"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="15">
        <location>
            <begin position="520"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="30"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="151"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="344"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="687"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="119"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="348"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="687"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="703"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="713"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="728"/>
            <end position="741"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1898028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="756" mass="83043" checksum="9E4BB3D5F809824E" modified="2025-10-08" version="1">MDILKILSRGAKKSSKASAHKSGTVAALKLPSAGTEANPQLFHDDLGSSRKRKRTNDTGDAHCKKTAIAASVGTKNINDDDLPELDFFAPKPDDTEDAIEPDGAEHGKSNDSETESEDEHTHDERLSEEEYRSLLHSHRLKVTLLSKIPTPVLPEKKSKKSKKGKKGEQEAKESTPTKKVDKKRLYPEPLTSFATLRTTYKISRRLAENIAHQAYKIPTEVQMGALPLLVNARRALSDAERQLLISVDDQEEPVGVDLLAVAPTGSGKTLSFLIPAINAMASRRAKLPKPADNVEDVHELEVVVLAPTRELGYQIVNEARKLTQGMGLRVAMMRKGMRIAADKGVEINLEEQEEDDEDAGSSDDEDGEEDEDEDKDTPKGVTKVDILVTTPMPLLNFLRKDAKDGTSMTLPTVRSLILDEADVLLDPLFHEQTTGVWKSCTYPNLQHSLWSATMGSNIETMVTEALETRRAVTNAPPKPLVRLVVGLKDTAVPNIKHKLIFTGSEMGKIYAIRQLLRPGSRSDDTISIRPPFIVFTQSIERAAALQDELRYDIPLEAGGSARIAALHSGLTDAQRASIMRQFRAGEIWILITTDVLARGVDFAGVNGVVNYDIPGSSAVYIHRAGRTGRAGREGGIAVTLWTKDDIPYVRVIANVIAASDKQAGRVGEDLGVPASLLASLPSVSKEDKKKLRERGVEARRSGGASSKITTKSGWERQRMNNREAAVKQSKHMRKEEKRRRTTDKTGENEEWGGIDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBU0</accession>
    <name>A0ABR3ZBU0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">NADH-cytochrome b5 reductase</fullName>
            <ecNumber evidence="13">1.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">MCR1</name>
        <name evidence="15" type="ORF">Cpir12675_002133</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">May mediate the reduction of outer membrane cytochrome b5.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>2 Fe(III)-[cytochrome b5] + NADH = 2 Fe(II)-[cytochrome b5] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46680"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion outer membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.2.2" evidence="13"/>
    <dbReference type="EMBL" id="JAWDJO010000038">
        <property type="protein sequence ID" value="KAL1898044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090524">
        <property type="term" value="F:cytochrome-b5 reductase activity, acting on NADH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF171">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0274">FAD</keyword>
    <keyword evidence="4 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="8 13" id="KW-0520">NAD</keyword>
    <keyword evidence="7 13 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="14">
        <location>
            <begin position="84"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1898044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="335" mass="36264" checksum="CFF631E97B5C1C2F" modified="2025-10-08" version="1">MFARSAIRITRPLRQQVRAFASKSPNAVPKSPELAPKPSSNSALYAAGAAALAIGGYYLSNGNGAKASAATPVEIKKAFTGGPQGFLSLEVSDVKDLSSNAKLLRFKLPDSESISGVIFTSAVLTKFKPEGAEKAVIRPYTPTSDEDAKGYMDLVVKKYPDGPMSSHIHNLKPGDKLDIKGPLPKYPWSANKHPEIALIAGGTGITPMYQLLRGIFSNPEDKTKVTLIFGNVTEDDILLKAELDKLENTYPQRFRAFYLLDKPSSSWKGSKGFVTKELLKTTLPEPKQENIKVFVCGPPGLMNAVSGNKVSPKDQGELKGALKELGYTAEQVYKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCN5</accession>
    <name>A0ABR3ZCN5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF3835 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_002124</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000038">
        <property type="protein sequence ID" value="KAL1898037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024325">
        <property type="entry name" value="DUF3835"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039553">
        <property type="entry name" value="Prefoldin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052255">
        <property type="entry name" value="RNA_pol_II_subunit5-mediator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15111">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT 5-MEDIATING PROTEIN NNX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15111:SF0">
        <property type="entry name" value="UNCONVENTIONAL PREFOLDIN RPB5 INTERACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12927">
        <property type="entry name" value="DUF3835"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13758">
        <property type="entry name" value="Prefoldin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3835" evidence="3">
        <location>
            <begin position="583"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="181"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="333"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="385"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="187"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="218"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="232"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="333"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="446"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="462"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="523"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1898037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="662" mass="72196" checksum="A9308CC781E8BD0E" modified="2025-10-08" version="1">MDTVKDSFLDLERQRQRLEDQASQLRQSLGYWRTWDADYETLKEEVDAIPEGARQSQTAILAVKEKFESSIVTAKELDVIFGSNAKPKTYAQIISVLDGRIDTGSKNVASLKRGLESTENKLAATTVIMNPDGTDEDGQPFTDIIEELDDDDNVISYRLAKPGDNSNQIRELLEKTGVKGLLPMLDGNTNEGGSSPGSAKESLKSNTAKKQALQGLISASPSSESPSPQLKATEKASEKQTARAKPPPPETAAASTENARSIPKSEVPTPLPRAAQRVQNIMDSAKAQEEISKTEPVIPENESEDDAQMRRHMLTYGLGEVGAVVAEMFIEDGDDDDWGTEDEEYESDESDEFGKSKYSVITDDYRQHMLELEKKLGFQSRFSRQLEKKIAAQSDDEEEGPEKEGIGRIVVQTQDKPLAVSSAASASSTTPVKNPPGSPAIESSLKKTNANKATGSSGDGADSVKLEAEPKSAKKSVRFAEMLDIAPQKPGGKPTPRRAKLPKVTDDDLPDTIGDVVECKSSSKNRRKKANKKASRFKKAMAETQTLSTPAMTPDAIPSAFSLDGNKISGSAAAPTPPQGQTLATAVVEKPTPASEKVIINDEFDGLTLQQEVSDEYHKRRKNIIQQHGGFLVQEELPIQRVEEHDQTKRVSRFKAARLSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDE4</accession>
    <name>A0ABR3ZDE4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001967</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000034">
        <property type="protein sequence ID" value="KAL1898342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13298">
        <property type="entry name" value="PH1_PH_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13299">
        <property type="entry name" value="PH2_PH_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051707">
        <property type="entry name" value="PI-Interact_SigTrans_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14336:SF15">
        <property type="entry name" value="DUAL ADAPTER FOR PHOSPHOTYROSINE AND 3-PHOSPHOTYROSINE AND 3-PHOSPHOINOSITIDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14336">
        <property type="entry name" value="TANDEM PH DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="60"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="301"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="415" mass="46876" checksum="61E7452958D4A475" modified="2025-10-08" version="1">MSVAIPKPASQHDSTSNTADSQAPRLFHKSNTNDSISRQCDRRILGNSPVDQNGSFEFDRVLKSGYVQKRTQKTKTWKSVFVVLRPTSLSIYKTERETKLRNKIELADLTAVVHLKDPKHKRDHVFGLFSPSRNYHLQASSEAEANNWVDLIRTQARIEEEEEEMFLQSPQVRSGAAFMDRMFNKKRPMVGESGGCNTASGLNDDRVLSSSPELQVKPPTPRLNSPPMSMVMDYSGLSGNEMASDFSDADVPRRFVPIASDKKSASVVHEDDPATAKRLSMPQVPPTTNSVGHTTVPDPDRVIWHDWLWMQRSKGGVRQWRNYWAVLRPRNLILYRDQTEYTAQFILPLGSIVNAVDMDPVSKTKKYCLQVITEEKTFKFCAHDEESLVQCLGAFKSLLAKRRELEAAAAAHARN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDE5</accession>
    <name>A0ABR3ZDE5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Putative gamma-glutamylcyclotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_001924</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the gamma-glutamylcyclotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000033">
        <property type="protein sequence ID" value="KAL1898379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06661">
        <property type="entry name" value="GGCT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.10">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045038">
        <property type="entry name" value="AIG2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009288">
        <property type="entry name" value="AIG2-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013024">
        <property type="entry name" value="GGCT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036568">
        <property type="entry name" value="GGCT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31544">
        <property type="entry name" value="AIG2-LIKE PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31544:SF2">
        <property type="entry name" value="AIG2-LIKE PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06094">
        <property type="entry name" value="GGACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110857">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Gamma-glutamylcyclotransferase AIG2-like" evidence="4">
        <location>
            <begin position="8"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00030602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1898379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="164" mass="18557" checksum="26FD48875A000494" modified="2025-10-08" version="1">MSGDYTAFFYGTLMVPEVFFTVTLNTASPPKPLSDLYTFCPAVLKDHARHRVVHEDYPGVIAEQGHSVVGVFATGLTDANLEKLDLFEGPEYERQLVRVTVLDKNGKVVSEVKTNTYIFTDANRLEKREWDIEEFKSEKLSLWTCNEFVFEGCHVPANVKTNST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDI0</accession>
    <name>A0ABR3ZDI0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_001738</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000029">
        <property type="protein sequence ID" value="KAL1898735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050587">
        <property type="entry name" value="GNT1/Glycosyltrans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11183">
        <property type="entry name" value="GLYCOGENIN SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1898735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="151" mass="17625" checksum="8B48F2134C7A5EBE" modified="2025-10-08" version="1">MSYLNGELLVLVPSTALWERILSYIHTNAPGMDFADQSVLSELFSRRWVPLPYIYNAPCTMRWKAVYEVVWRDNKVKNLHYILDPKPWVAQTGAVGMRLEKDPAYQWRVDIDQQRKTWHKNNGITDGLRILYSGAARDGGYRIYQDCDVIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDK1</accession>
    <name>A0ABR3ZDK1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA replication licensing factor mcm10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_001978</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MCM10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000034">
        <property type="protein sequence ID" value="KAL1898352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040184">
        <property type="entry name" value="Mcm10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055065">
        <property type="entry name" value="OB_MCM10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015408">
        <property type="entry name" value="Znf_Mcm10/DnaG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13454">
        <property type="entry name" value="PROTEIN MCM10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13454:SF11">
        <property type="entry name" value="PROTEIN MCM10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22379">
        <property type="entry name" value="OB_MCM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09329">
        <property type="entry name" value="zf-primase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MCM10 OB-fold" evidence="10">
        <location>
            <begin position="371"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger Mcm10/DnaG-type" evidence="9">
        <location>
            <begin position="517"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="102"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="231"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="695"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="37"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="71"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="161"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="232"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="249"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="697"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="713"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="768"/>
            <end position="778"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF22379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1898352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="862" mass="94237" checksum="F429F2B820CF950C" modified="2025-10-08" version="1">MIPSQRDEPQWPPRSPRDALLLTPRGREKYKAMTAEQQRQLQMSPSSPSPLRRARIAHTPEPFEQALGGLDGDDDDDEDEDEETLQLKLQAIQARLKLKKLQKEKKLQASQSRQPSQTSPGTPVKPKPMGLLDSPAMFANLPKSPASVGKSSARLAYTRPSASANASSSVSSSVSAIPDPMALKPPILPPPRATVATPVAEREVEVPLSPVQRVHKLVEATSPLRKILSRGLRGEDVRLDKPGKPKLNDSFSSKESGGVSTSTGYLRTARGTAQHKQQAGLAPVEDRPLSFNERLALAKAEHSEKLERQERIQQVRSNTFGITQQEMQTFKEKAVEIVQEPKAPHHYTREEIMGTTKPEVEKKSEASFESYSSFHLTNRILPHQVVARHMQDSKIFSVTDLTKVVKAPDFELPEIEQNIVVFAILARKSDPRTHKPNAAQPNKKQESKYMVMTLVDLNLDVELFLFGTGFERFWKLTEGTVLAILNPNVMPPPPGKKDTGRWSLVINSDADTILEIGTARDLGYCKSVKKDGHPCGAWINSKRTEYCEFHSNQALQKIKQGRVEMTGSGFGRSGKDWNGMTAVTNKKFGKGGAGYAIRKNGGMSSELNRGKGHYDFDSQSNFFMSRTRSAADMMDGKHLTMAEKQEREDNLRRALIAKEKERDLARKLAGRGGSGVGHEYMAKFAGKPVNLAKPSISADSGGSGSFTPVSAGTSTSTPISSSHSTPTLTLAGISRGRRAEDVDLTSGKRKRVDDRTISADKPTPSATGGSGPSYGWGSGLSSKLGRMKGGERLCRQNIQPSTADEPDRKKTRFVTEDGVKEAGRESAQGMRSLASAPGMEMDLGDVDFVLEIEGAPPGFNLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDL5</accession>
    <name>A0ABR3ZDL5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Guanine nucleotide-binding protein alpha-2 subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">GPA2</name>
        <name evidence="11" type="ORF">Cpir12675_001884</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the G-alpha family. G(q) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000032">
        <property type="protein sequence ID" value="KAL1898419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002975">
        <property type="entry name" value="Fungi_Gprotein_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF369">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-2 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01241">
        <property type="entry name" value="GPROTEINAFNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0519">Myristate</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0564">Palmitate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0807">Transducer</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1898419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="301" mass="35049" checksum="96535782A22A840A" modified="2025-10-08" version="1">MKIIHLKGYSHDELLNYRPTVFKNLVECARAVVSAMRQFEIEPMNEDTRQYCDFILEYVPQAGPEAEIDPRVGPAVQAIWNDPAKFLLMERQNEFYLMDSATYFFDEVDRICDPAYLPNEMDVLRARTKTTGIYETRFVMDQLSIHMFDVGGQRSERKKWIHCFENVTSIIFCVALSEYDQVLLEESTQNRMLESLLLFDSVVNSRWFRRTSIILFLNKVDIFKEKLPRSPLGNFFPDYSGGNDVNKAAKYLLWRFNQVNRGHLKLYPHLTQATDTSNIRLVFAAVKETILENALIDTGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDN2</accession>
    <name>A0ABR3ZDN2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nuclear pore complex protein Nup85</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_001746</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Functions as a component of the nuclear pore complex (NPC).</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the nuclear pore complex (NPC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
            <location evidence="1 9">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the nucleoporin Nup85 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000029">
        <property type="protein sequence ID" value="KAL1898743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011502">
        <property type="entry name" value="Nucleoporin_Nup85"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13373">
        <property type="entry name" value="FROUNT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13373:SF21">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07575">
        <property type="entry name" value="Nucleopor_Nup85"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 9" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7 9" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="65"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1048"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="116"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="133"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="149"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="173"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1898743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1156" mass="126704" checksum="303ABC2FA46E698E" modified="2025-10-08" version="1">MSFKFSISDDPELPSTPDSRNFGNNFHFGPESSTSTTPGAPPPVSALASAPSLFTTSATPARAASIDDMASSRGGASNMFSAAGSSNSNNNTNTPFFGSILGGHSPRPPSHPVRGSRTSKPSGLSRSFRADSIDPEDEDDRDDDAGLQKKPVSNPPKKNVTGTFRLDDLLATSDDDDEDAEGDDDDQDVYHSGHGYYGGDEFKDPITAAMSKLVERDIDANYNNYSNSETIERSIEVDDDEDMFLSMRHNIDNMEDDEEVVEDLLLATPAATKRMKKEAESLARASRVAPGKQDFQFAQLCKDVYSQLPFATLESPDINSKGKEIIVKTEEKIMCLYNEGVGPIDDPEKLDSSMAVAAISLVNLWNSCASELPNPEEHDATIGPGQDAEPFRKASWIAHLLLLIHHARFIDEHSNGEPVPLPESLFGWMDSDHNPYASQTQQVLNFRPSPASNSLFWQTIHTVLIRGQVKHAIDLLANAGWEQTQKRLGTYDYTGRILANIKKAVQDTIDMLTECPGSRGNWNVWGSEWSLFRVNACASWERLSRFVEGRNHGFVPHGDPTFDTNSMADMSRRAESQVPWEIFQHLNIIYRIVQGDEGSILQTAQDWLEASVGICGWWDQEIDRRGMLRTSMLNKAGSSQQQSYAERLAAAFHVVVNSEFQLNIQNHCELAAASIFEGNFTATIGFLRAWSLPIASSVAEIGSLAQWLPKRETRAPKAMDDFDDMDLEVLGMAKQGPDEIDGMKDTTLVMYARELAGVDIIVDDEYGWEMATRVLGRLDSVTLAEETIRELLHDVLDSIDVNSSSSVERIWRILMDLGMTKFAEESAETYADLLSRDSCKYGEALWYYALAHKPNKVREVLNLLIFYSLMHSTVFPPEEDLDNRFESLLVDRSATLEQLAKQDVDAAQLLGRMLSGYATLRKFYETRDSYLSVPAGSARALAIKRQASAALVAVVASADDNIRGGLYDLSRDAVVSEDFLLALLGEALVLINTTAPSDPVLVTADQMDVLLKAIEDLQTVGGRVYDACVEFFNYVLAATPGGLKGSTPADLLHKGPVQGGPTPGPNGEASTSGASFVIAPSSLIASQLNRSISAASSKAVAGGVAVQLATARRGWDWRVGLRVGMGADEVLRVLRLGISRDLAKLWLQEVDDMAMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE21</accession>
    <name>A0ABR3ZE21_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">COPII-coated vesicle protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ERV14</name>
        <name evidence="7" type="ORF">Cpir12675_001838</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cornichon family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000031">
        <property type="protein sequence ID" value="KAL1898634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003377">
        <property type="entry name" value="Cornichon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033466">
        <property type="entry name" value="Cornichon_conserved"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12290">
        <property type="entry name" value="CORNICHON-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03311">
        <property type="entry name" value="Cornichon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01398">
        <property type="entry name" value="Cornichon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01340">
        <property type="entry name" value="CORNICHON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="138" mass="16166" checksum="53558046767222F2" modified="2025-10-08" version="1">MSGEAWLYLLAVLINAVNLFLQVFFTIMYSDLECDYINPIDLCNRLNTYIVPEAAVHGFLTFMFLINGYWLPLILNLPLLAWNIKKIFDNVHLLDATEIFRKLNVHKKESFSKLAFHLVMFFFYLYSMIVALIKDESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEZ2</accession>
    <name>A0ABR3ZEZ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="11">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">DBP7</name>
        <name evidence="16" type="ORF">Cpir12675_001544</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="11"/>
    <dbReference type="EMBL" id="JAWDJO010000025">
        <property type="protein sequence ID" value="KAL1899260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17949">
        <property type="entry name" value="DEADc_DDX31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025313">
        <property type="entry name" value="SPB4-like_CTE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13959">
        <property type="entry name" value="CTE_SPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01178">
        <property type="entry name" value="DUF4217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 11 16" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 11 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="8 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="15">
        <location>
            <begin position="145"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="177"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="436"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="23"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="383"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="733"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="10">
        <location>
            <begin position="145"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="27"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="130"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="385"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="738"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="763"/>
            <end position="775"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1899260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="809" mass="88413" checksum="8FF272EA584291FB" modified="2025-10-08" version="1">MADDGILVNFEIGDFPVKQNVKFQGGRWRDRVRAQKSARREADGTVSSHDEPAKRKEPSQRPSDDSDDDSRPSKKQRPNQPNLGSNNSNNNASRGPSKRPVGPGKHVTSSLFSSNPQHVTDMDQERAADSTPTEPTNAPLTGPAASFAALGLSDRVVRELAKMELSHPTAIQKKTIPLMVNTEDDAFIQAQTGSGKTLAYLLPMVHRVLALSKQSKIQRDSGIFAIVLTPTRELARQTHAVLQQLLKSLPWLVASAITGGESKKAEKARIRKGINFLVATPGRLSDHLTNTQVLKLSTVRWLILDEGDRLMDMGFEEDVKKIVTMLRKAEVATKSYDGMPLEILPKRRVTVLCSATLKMTVQRLGEMSLDDAVHIAVTKGDLDEEKEHAEKDKADDSKDDKETTSLHETETKEPDAAEASTGHLVVGGKAYSAPAQLKQTYLIVPAKLRLVTLLSYLKFMFARRDTVMKAILFISCADSVDFHYDILRKPKPAFAPTIPREAGGSNTPDTVSEASYITSAANPRVLVHKLHGSLPQSVRTATLDSFSKCKEPGLLVTTDVAARGLDIPDVDHVIELDPAFCVEDHIHRIGRTARAGRAGKATLFLMPGSEEGYVELLKAGSAPVPLLYDSVLKNAMALPWELPTETHARMEDKSFTRQAENLQLHIEQRLLDPNNKEQLELGRNAFRSHVRAYATHVKEERVFFDISNLHLGHMAKSYGLRDAPSGIGKNIERKASKAAKAANKRTSGSRSGSRTSRVNGAGNTSGGGTGTGSNAGAGDDDAEAMLAARRMLRKKSMMMMNTASEFNIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF15</accession>
    <name>A0ABR3ZF15_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein DGCR14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_001938</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ESS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000033">
        <property type="protein sequence ID" value="KAL1898393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019148">
        <property type="entry name" value="Nuclear_protein_DGCR14_ESS-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12940">
        <property type="entry name" value="ES-2 PROTEIN - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12940:SF0">
        <property type="entry name" value="SPLICING FACTOR ESS-2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09751">
        <property type="entry name" value="Es2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="263"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="309"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="411"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="309"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="336"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="449"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1898393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="472" mass="52449" checksum="06A38ED9874243B5" modified="2025-10-08" version="1">MASPDPQPSKALVRKRDATVDMQLMAPPPPPAKKIKRPKKVLDEESYTEGLSQIIMRDFFPGLQEIQLQNDYLDAVEAKDRLWISTATHNLIDGKTPDQKPGLWCDTPSSTRRFVKNETPSTILDVGTPASIAPSIGPSSRARVNTAMRLSQFQATYTSEDNESFYALADRQNQKKTEKQAWLWNGNKFDSKQLIKQKEVQQQLSNAGQLHDDGFMKKDRLAIKDSDDRPAQPELWKWRPKNTLMFTPDGIEDQYETRFQRAEASSTSAPKGINYHNTRVPTRANTERPLRPPSPTLTAVRDALAGNVPQTYKTPSEIGSTLAGGETPRINGYAFVDDEDDEGGEDEHPLPKINLGPGDATPSPFRLQERTKKEDLLHRMVDRINKSHHTALRNGFTGKADATPIPKFMNSPRASSVGSLTPAAQRLLGKIGASQTPARGSTQREGRTHSSFASSTPMASRGFLTKRTPKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFN9</accession>
    <name>A0ABR3ZFN9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Extracellular serine-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001598</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000026">
        <property type="protein sequence ID" value="KAL1899042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052953">
        <property type="entry name" value="Ser-rich/MCO-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883:SF15">
        <property type="entry name" value="EXTRACELLULAR SERINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883">
        <property type="entry name" value="SERINE-RICH PROTEIN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045163235" description="Extracellular serine-rich protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="176" mass="18816" checksum="71E12FA169A2A30F" modified="2025-10-08" version="1">MQFKLASSLMLAVAATSVLADSSTESQEPVRIVIKLNAYGFQPSNVKAKVGDSIEFHFGEGTSSVVQSDFATPCKAMKNGFSSGTFIVDTTMDHNNEGPHIFVVPVTSTNPVAFYNGIKSQCYGYGAVGVINGQEDTEQSQDKLKAKAFASHGISENPNLVRGGIIEANPEYDDIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG49</accession>
    <name>A0ABR3ZG49_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein DSF2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000019">
        <property type="protein sequence ID" value="KAL1899703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052945">
        <property type="entry name" value="Mitotic_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628:SF11">
        <property type="entry name" value="PROTEIN DSF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="382"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="656"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="254"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="448"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="663"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="681" mass="74267" checksum="DCA309C2EB4D74FD" modified="2025-10-08" version="1">MDPPRPPFLELRSISSSSQRSIKPSMRSPRLHVAGEAPPELSPLDAFALQSRLLAKKLEESNREGRRMSRLPPLTSESPLVVQSRSEYFRTMSQDSLSENGDSPALNEPASGLGVRTEIEEPLPEMRPRSMHPRMSHMPPIDQEAPVPQFSEMMRGRASTLSNNGSVNFGARREASPEMIDSRDDNLLTPPGKRSPSHDSHLAPTLPSPSKSPPKNEASTEMTGLAPPRAIYPRRSSSILSGPPTDDDQAGSFYSRSPGSRKMSSSSSVYGGGYGPALGPRSPSVTPSTTSELRRPSFNFSRPISRAGTPSLDLPLPTRQTSSDSQPAFMNSDEIAHTPVSMNSEAFESFEESRSPGSTYIYSTYTLPRGKTIQRSVPLDATSVSEFGGSPKSVKSAVSGAPPSPPTRPSSSASRVTQSNLTLPNSEEDSPRKNLASPITESAKLRTAMSSVPSDTASTIRPHNSSPPTAAEMSAEEHLDTGIECHENGSLNESTYHLRIAAKQNNPTAMLLYALACRHGWGMRPNQKEGVEWLRRAAELAQEEIAEDEEHAKEGKKVNTLENKTRKAQFALSIYELGVSHMNGWGIEQDKKLALKCFEIAGTWGDVDALAEAGFCYAQGMGCKKDLKKSAKFYRMAEAKGMNMVGNSWIHKAKYDSDDESKKKKGKSRSHRHLFSHKSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGR9</accession>
    <name>A0ABR3ZGR9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dipeptidase</fullName>
            <ecNumber evidence="2">3.4.13.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001433</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid</text>
            <dbReference type="Rhea" id="RHEA:48940"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:59869"/>
            <dbReference type="ChEBI" id="CHEBI:77460"/>
            <dbReference type="EC" id="3.4.13.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.13.19" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000022">
        <property type="protein sequence ID" value="KAL1899397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01301">
        <property type="entry name" value="rDP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008257">
        <property type="entry name" value="Pept_M19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443:SF12">
        <property type="entry name" value="DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443">
        <property type="entry name" value="MICROSOMAL DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01244">
        <property type="entry name" value="Peptidase_M19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51365">
        <property type="entry name" value="RENAL_DIPEPTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU341113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="459" mass="50575" checksum="C4B8DA8A599B8E0D" modified="2025-10-08" version="1">MSSQPLLNAAPSGQLLSTTKSRSRLKCGLPKGFKTLVATAIAVAVVLDAGLNNGGCIDVIWDRIFGPRTIGQRVNHILRSTPLIDGHNDLAIYIREHYKNHIYYDNFSQPFSQGGFPGHVDIPRLREGQSGGAFWSVFTPCPDNGSDFSDENYAASVQFTLQQIDLVARLKNAYPDEFAADGDSAHSLASFYKGHIISPLGVEGLHQIGNSVANLRRYYDMGVRYATLTHNCHNAFADAALLENPFRVAEPFWHGISPAGKKLVHEMNRIGMIVDLSHTSEETMVDVLGGNDWEGSKAPIIFSHSSAFSICQHPRNVKNHVLDLVKKTDSVVMVNFSPSFISCMPPKTPHDVPELEPENSTLEQVVRHVKYIGDRIGYDHVGFGSDFDGIQTTPEGLDDVSKYPSLVGKLLEEGVSDADARKIVGGNVLRVWRKTEAMAHELQRQGFPVLEDNLKELSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHF6</accession>
    <name>A0ABR3ZHF6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AMMECR1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000021">
        <property type="protein sequence ID" value="KAL1899627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.700.20">
        <property type="entry name" value="Hypothetical protein ph0010, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.150">
        <property type="entry name" value="Hypothetical protein ph0010, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023473">
        <property type="entry name" value="AMMECR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036071">
        <property type="entry name" value="AMMECR1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002733">
        <property type="entry name" value="AMMECR1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027485">
        <property type="entry name" value="AMMECR1_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00296">
        <property type="entry name" value="TIGR00296 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13016:SF0">
        <property type="entry name" value="AMME SYNDROME CANDIDATE GENE 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13016">
        <property type="entry name" value="AMMECR1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01871">
        <property type="entry name" value="AMMECR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143447">
        <property type="entry name" value="AMMECR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51112">
        <property type="entry name" value="AMMECR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMMECR1" evidence="1">
        <location>
            <begin position="13"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="226" mass="25438" checksum="83C2E2C15BA13C49" modified="2025-10-08" version="1">MASLIHSIACFETLDAELTSREPASLAEILASWPSYTSANPSAPSRSADTSSAQPDDICPLFVTWNIYETPGTQPHLRGCIGQFAPGLLADALPEYAVVSAMHDSRFRPVTAKELPQLQSAVTLLTDFEECSDKFDWEIGLHGINIKFMVGGRSFSGTYLPDVMVEQAWTKEETLENLVHKAGWRERMGDWQKLDLRVQRYKGSKAKAEYSDWLAWSKWYQTQEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHU0</accession>
    <name>A0ABR3ZHU0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_001199</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000017">
        <property type="protein sequence ID" value="KAL1899975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057072">
        <property type="entry name" value="bHLH_INO4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052207">
        <property type="entry name" value="Max-like/E-box_TFs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15741">
        <property type="entry name" value="BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15741:SF39">
        <property type="entry name" value="BHLH TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23181">
        <property type="entry name" value="bHLH_INO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="7">
        <location>
            <begin position="19"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1899975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="94" mass="10583" checksum="479F6DA8AA8736FB" modified="2025-10-08" version="1">MSDSGQSPEDEKPRLTDDQKKQNHIASEKKRRQAIRDGFDNLCSLVPGLEGQGRSEGLVLGRAVDFMKEQVARRRELIDRIEQQGGVVDLSYAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIL6</accession>
    <name>A0ABR3ZIL6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Eisosome assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">EIS1</name>
        <name evidence="2" type="ORF">Cpir12675_001425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000022">
        <property type="protein sequence ID" value="KAL1899389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024527">
        <property type="entry name" value="Eisosome1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28298">
        <property type="entry name" value="EISOSOME PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28298:SF1">
        <property type="entry name" value="EISOSOME PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12757">
        <property type="entry name" value="Eisosome1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="422"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="487"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="800"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1065"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="487"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="533"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="597"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="624"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="697"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="721"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="753"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="771"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="800"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="868"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="914"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="941"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1065"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1100"/>
            <end position="1122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1122" mass="119782" checksum="57FF58B5A0ADBFE8" modified="2025-10-08" version="1">MATLHSKKTPTASGAGGVTMDHCAAAAHYGWYNTKSPVVHRPSNGDFSMAAANLVLSRSTTASMSAPVSASASAAASASALAAIPRSSLPKQTGQRSPGRLPVSQRQSTVSTQNPPVPVDKLDKDAWSMAAARGALEQSFIKPKANKQQDQQHNTQLLSQALPLKLKQPLQQRRYSMQPPTRAPSGQALSAATVAHAPYLDNAQRRASAPPLYATRPRSMYSASTLTNGNLNLGASGYDRSRQEEIHATALAMAQQMFAQQQAGSSKGKQKANMASAGATHDPLHEKAWKLAQARLAQMDDGSLVVRDSQSYYIAEDRTSSRKFSRLGRRHNRRDDGSSGADGDDSDAEDSDFKAHADDQPRSIFARRLSSMQIRKRQSERDALLAAARRNVENTMAEIDEETMATTGRLHPRHVTAWEAKAREAAAHRKAKRDRADEDGPDTPVSSWAGPSDKYNVGGGVTVDKTEVEALANQNLEPLFTDIRESAAIEKERKEQQRIEQETKKQEESADKARKGKLNEIVSIFNSQKKREKKEEKKQAKLAAKEAKRKDKERTKGSQKHSKLKDSISAPVPIPGLEIPAMGASTQHLATTAGEPSATSKPATNTVAPVDSTAVTTGSPTVNPAIDTVAPADPTAATAASSTVSPAELALPESPIGHSALGISSPASEAVPAFISTPTYPDEPVPTIPDKSADRNLPTSSETAVMSATVSPEELHDFPASSPTGLSPIDESSTPTPDTTVIAAVPFTDGSPDASTHATTIENNAASQVQHETEPAEASNKHEPVVPMAVLAGAGVDAATSTALESSHQTAADALGSPLHPLQSNPPMIEAKKRINDNINVDSAYDPNYDQGAQQQEKEQENSSSTQKPQKTPASMPTVTASSVDGGLSNSAPAQDPTTPKAEHKAKGVPSSELSRDERREASLERARQTQLNAASVLPEQQKRISRADHADEEYQIPLESETSSADRVRNWFRTYVRSRKDISQVGGLDNSDMLVAGADPVPHTHAQTGVASTLSPGYPSANGADTVVGNRTEGIDGAERSIKQKKRSSFFNKLAPSLSTKDAKVDEKREFVHEPNLARGKSNGITGGGLDVPPLPKHLKQDRASPVATDERASRFKEVMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIM8</accession>
    <name>A0ABR3ZIM8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000022">
        <property type="protein sequence ID" value="KAL1899404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="248"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="391" mass="42530" checksum="8B63E006C4B95B6F" modified="2025-10-08" version="1">MLAAHNDNLLRPRGLAPKTPGARRLLHDENAVTMGKKVLGGPARDQNQENTVLRGKQTSFATPMASAQTRAPLGMKTTNAKARTNHLGGGKQVLKDNIDNAVSRPKPKPTVFASSKLDIRCDPKPAKPESEVECASIAPEIPYESDILPIGGLSLNCLKPENLFGGYYEHFIDPTNDKGKRLHTLKLEEDFEKALRASEQDIMRDIENTDWTVADVPESQQHLRKKKTAVTSRPASVTSNSRLRHTRAASSMSTRSAASTLGSAPASTLSRVRQAPLVHKHTKMPSWLQPKKQPVQGISDPIKATVSQTTIGYSKGRSASASIREPRSAAGTDSLGSMGPEETVVVPSPTHKHTSRPQFVSIFDVAEESDQEDSFKAGSQAIDYDDDDFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIU1</accession>
    <name>A0ABR3ZIU1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytosolic Fe-S cluster assembly factor nbp35</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">NBP35</name>
        <name evidence="10" type="ORF">Cpir12675_001008</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000014">
        <property type="protein sequence ID" value="KAL1900324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02037">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03038">
        <property type="entry name" value="NUBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028601">
        <property type="entry name" value="NUBP1/Nbp35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23264:SF35">
        <property type="entry name" value="CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23264">
        <property type="entry name" value="NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 8" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="7 8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="87"/>
            <end position="94"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>ligand shared with heterodimeric partner</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>ligand shared with heterodimeric partner</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1900324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="345" mass="37121" checksum="F764D47AAAA6AE7B" modified="2025-10-08" version="1">MAHAVDVSQEDPEDVLQNPLRKKPDLVAPEPEHCPGPESEQAGKADNCAGCPNQAICASAPKGPDPDIPQITSRLKGVKHRILVLSGKGGVGKSTFTSLLAHAFATNPDTTVGIMDADICGPSIPKMMGVEDETIHVSANGWSPVWVMDNLGVMSIQFMLPNRDDAIIWRGAKKNGLIKQFLKDVEWGDMDFLFVDTPPGTSDEHLSVNTFLRDSGIDGAVVVTTPQEVALLDVRKEIDFCRKAGIRILGLAENMSGFVCPKCTHTNAIFKATTGGGAMLAKEMGIPFLGSVPLDPHIRMACDYGESYFDSFGDSPACKAFMGVVKCISEQLNLNVDDVIPKEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ19</accession>
    <name>A0ABR3ZJ19_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Plasma membrane proteolipid 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_001151</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0057 (PMP3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000612">
        <property type="entry name" value="PMP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659">
        <property type="entry name" value="HYDROPHOBIC PROTEIN RCI2 LOW TEMPERATURE AND SALT RESPONSIVE PROTEIN LTI6 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659:SF57">
        <property type="entry name" value="PLASMA MEMBRANE PROTEOLIPID 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01679">
        <property type="entry name" value="Pmp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01309">
        <property type="entry name" value="UPF0057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="89"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="100"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="162" mass="17404" checksum="DC87213FCCECA169" modified="2025-10-08" version="1">MCCSPCSNDLFLGLLAILFPPIAVWVKRGICSADSVINILLCLLGFIPGLLHAWYIIAKYPDPTYEYESLSHDNDDRVTYVIVRNGQRAQNPTHSHTHPHAAPQTHAPMHYGTTMHAAPAGSQSQAQGYSAAGPSNGGEGASDMSVPPSYAEVVAGDHKIQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJF5</accession>
    <name>A0ABR3ZJF5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome c oxidase subunit 5B, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">cox5</name>
        <name evidence="13" type="ORF">Cpir12675_000724</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome c oxidase IV family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00922">
        <property type="entry name" value="Cyt_c_Oxidase_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.442.10">
        <property type="entry name" value="Cytochrome c oxidase subunit IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004203">
        <property type="entry name" value="Cyt_c_oxidase_su4_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036639">
        <property type="entry name" value="Cyt_c_oxidase_su4_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10707:SF10">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10707">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02936">
        <property type="entry name" value="COX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81406">
        <property type="entry name" value="Mitochondrial cytochrome c oxidase subunit IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="125"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="142"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1900848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="168" mass="18533" checksum="5D17ED1A35A09787" modified="2025-10-08" version="1">MIRTSTSTLLRRTIARAGMPTTSTRAASTALSKPTLANIEKRWEGMPMQEQAELWMSLRDRMKENWKDLSLQEKKAAYWIAFGPHGPRAEAPAGEKARVVTGTFIGIGISLVIFLAIRSFAKPGPESMNQQWQEAANEKLKSQNADPITGISSPGYTGKGQVQSPPRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJP9</accession>
    <name>A0ABR3ZJP9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Trafficking protein particle complex subunit 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_000914</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012880">
        <property type="entry name" value="Gryzun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021773">
        <property type="entry name" value="TPC11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14374">
        <property type="entry name" value="FOIE GRAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14374:SF0">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11817">
        <property type="entry name" value="Foie-gras_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07919">
        <property type="entry name" value="Gryzun"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trafficking protein particle complex subunit 11" evidence="3">
        <location>
            <begin position="341"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="domain" description="Gryzun putative trafficking through Golgi" evidence="2">
        <location>
            <begin position="639"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="468"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1243" mass="138989" checksum="5113B7524950DE74" modified="2025-10-08" version="1">MDAFPEASLMHNAPLLLVTGLSPTAPTVKLKLGDSIDNAAIFIRSDMPPVSSPVAAHLEHYLKAIDATLPPWDNDFKDAPYRFRTIITSRTLCLPPRKAPIPIDGESSQQAPLVLHSPFSPLSTTSHLYPDGILDNNWLRKHQDLIPSVILFFYSLVSDPNQAQVEDNKLKTDMANIRTALSKSGHKIRLVAVLLSDAEASPLAPTDGITERLENIRKGAGLDHKAIFYVSPKNTPKEVEVAADKILTALYPTAVEYYRDLSKRSKKKRSRGLTPVPTVPPTSGTSQTLSLAHWHVRYDLKIGIFAEFRHDMEAACKAYEQAYESLTSQDVWEMIPGWEPRWNEARFLADITAIRWIRCLLWNGQPSAAVQRWQMHRDLVVSMVDRHGRGTNNYGWEAWQARWYLIMAELMEKMSMPDMPPFAQAVYLPPEKTISSERLRPWHSLHHTGYWYRAASRHQAARRKLALLIPEDDRKKPEDDPLQAESRKSTKDYSYDTYLCPEPFEELPLDGPGSNHGQLIVDSLVAAHKAFEQRGQRRAVAEVAIECAKELTAMGSASKAVDLLLPLWQDPMFRAHDWLEIIEDICWSLRKAAVKTNRGDVVLSVDWEMMSNRFSRLPQWPYDISKSLEGLTLAKRPVVELSDESVTPFISAVLLFRYKEARAGETCLAQLQITTETFIDVAALELTELQIKFEGGIGPIKITNNKESAEKVKTDKNVSIVAVKLEEETATGEDNGIDKDEIAPALHGTSCLISKPRQTTVFHLSIPLREPGETQAIGLSLIMDTEAYSLTYKTSFKSSRALNSWYDPVSLRHTTIAREAPHTLDIQPRPPKMELSLVTALQQHYTNESLELELDVYNAEHEDITAKVEVLAAGQDVPSIFLVHGETTVSSVSRSEGQTVSSTHIGSILQSERCKLVLRFDPFMVPTECQVSVKVLYHLHNDPATPILQSMSFKFSPKAPFEAGYELSPRLHPDPWPSMFGIDGLIHTGDTNTEPNPVAPVSRGLSQRWSLTCNYRSLAADELVIRDVGIRVLSPEDKVQCIATLETLLPTEGITVATVEKPRSAAFNIDVQKRNLDDRAPALMELAFDIHWTRKMAAADATTAPPFNITSIVVPPHMVLGTEPRVLASLSQPVGAPRGLMCMDVVIENASGHFLTFSLTMDPSDQFAFSGPKMTTLNVLPASRRTVNFRLFPMVSGTYIRPALVVKDKYYQKILRVIPTQGMSSDKDGLLIWVPQEAGEERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKL1</accession>
    <name>A0ABR3ZKL1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">D-arabinono-1,4-lactone oxidase</fullName>
            <shortName evidence="9">ALO</shortName>
            <ecNumber evidence="4 9">1.1.3.37</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">L-galactono-gamma-lactone oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ALO1</name>
        <name evidence="11" type="ORF">Cpir12675_000823</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-arabinono-1,4-lactone + O2 = dehydro-D-arabinono-1,4-lactone + H2O2 + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23756"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:16292"/>
            <dbReference type="ChEBI" id="CHEBI:58277"/>
            <dbReference type="EC" id="1.1.3.37"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Cofactor biosynthesis; D-erythroascorbate biosynthesis; dehydro-D-arabinono-1,4-lactone from D-arabinose: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.3.37" evidence="4 9"/>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007173">
        <property type="entry name" value="ALO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010031">
        <property type="entry name" value="FAD_lactone_oxidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006093">
        <property type="entry name" value="Oxy_OxRdtase_FAD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030654">
        <property type="entry name" value="Sugar_lactone_oxidase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01678">
        <property type="entry name" value="FAD_lactone_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762:SF1">
        <property type="entry name" value="D-ARABINONO-1,4-LACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762">
        <property type="entry name" value="L-GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04030">
        <property type="entry name" value="ALO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000136">
        <property type="entry name" value="LGO_GLO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00862">
        <property type="entry name" value="OX2_COVAL_FAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0274">FAD</keyword>
    <keyword evidence="5 9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="10">
        <location>
            <begin position="34"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1900689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="521" mass="59580" checksum="6F106C43A7A67F29" modified="2025-10-08" version="1">MNSSIGDEIHKASGDGVPFRARPNHVHRTWARTFSSLPELYIQPESLAEIEKVVNLARRCRRRLVTVGSGHSPSNITCTSSWLVNLDNYNKIISLNAETGQVVMQSGIRLYMLNDILERHGLAMPNLGSINEQSIAGVISTGTHGSSLQHGLVSESISSLKITLADGSTQYCSAEENTELFRGALLSLGALGIITEITFQAVPAFKLRWDQVIDADSRVLITWDTDLWTRGEYVRVWWLPHTRRAVIWQANRTDDPETPPPTGYYGGILGYYIYHNLLYLGLWIPKVLPWVEWFVFGMQHGFHNGTHKSAVQQSRQALLMDCLYSQWVNEWALPLQKGKEFLRRFSTWLNKLPPSDPDYMEPNIPYSSDGLYIHSPVEVRVSDSRAKGAIRPYLDTSMVDSPTLYVNATLYRPYDMDPDYLFRYYAAFEHIMTELGGRPHWAKNFHTTAKDFEAFYGPDLEAWRQVRNSIDPDGMFAGPWHRKMVLERNRPKLELEEELVEEQTQHRAGTLFMGRQVEEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKQ5</accession>
    <name>A0ABR3ZKQ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000546</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="139" mass="15645" checksum="D5B8DB835F163E38" modified="2025-10-08" version="1">MRTSGSEILASWLPPKLDLGVRTLFTIVQHNIPRKAVNVMSSPKKAQDTAAPSGVASEAPKRDRPKWYYRLILLTIKKYRDVEDEDFDEDLSELEESDDAGDKSDCEDPVCNCEDSDCECDHESLASSLEDNLSERSYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLK6</accession>
    <name>A0ABR3ZLK6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_000547</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1901314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="138" mass="14851" checksum="F05582CDCC4CD290" modified="2025-10-08" version="1">MNIIKDKGEALHALAADMTEVLNKAIGKSKGDPGLKQLAANISYAKVAAKGAKSKAVVSSDKITNAKFTTKSAAKPREQSLAKDEKVGVFIRGPSKPETDETVAAVARVMGAALEELQFKFNSSWSFMARRRSGAWRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLV9</accession>
    <name>A0ABR3ZLV9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000341</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046868">
        <property type="entry name" value="BAR_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046869">
        <property type="entry name" value="SLM1/RGC1-like_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31941">
        <property type="entry name" value="CYTOSKELETAL SIGNALING PROTEIN SLM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31941:SF1">
        <property type="entry name" value="CYTOSKELETAL SIGNALING PROTEIN SLM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20400">
        <property type="entry name" value="BAR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20399">
        <property type="entry name" value="PH_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="310"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="471" mass="51316" checksum="A3BCDFFEA6677C6C" modified="2025-10-08" version="1">MASITQPASPPGVDMPIRTSTGLTGLSGFSDDAIPEADPNTTAGLLAERLQAWKHAVVYLEDYITAVEKIHKAHAKEYEKALKTIANPLREGHHFDADAVGFASFFENIRLNTQAIVNTNLETEKSLKDAVLPILERLHKEIKLKVKELANGVGKGAKDVDKARGVTQKQIELLGQQAASYESAGARVSGHDDPYVVRRGVAHRLHKQVQEENNHRNELISVQANFCTFEAHIMGTISQTIEAFTGIVGGQGENIRMLHTDMLGAVQRVPVDFEWRKFQERCADRLINPNDPPRAVDSIVFPNMKHPSTLPVVEGLLERKSRNKLSWGHASGYYVITPSKYLHEFRDTDDVRADPKPELSIYLPDAVVSPPSGEKFSVKGKDISKNLSSKLTGSSELNFKASSAAEAQRWYEAMKDCATAGVSRVNSLASPAMPSSPVVADMKVPVASPTTPSVVAATQEAAVTGEKVAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLZ1</accession>
    <name>A0ABR3ZLZ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dipeptidyl-peptidase V</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_000371</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S9C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776:SF13">
        <property type="entry name" value="DIPEPTIDYL-PEPTIDASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776">
        <property type="entry name" value="SERINE PEPTIDASE S9 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="5">
        <location>
            <begin position="484"/>
            <end position="693"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1901681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="698" mass="78235" checksum="48B0A58C01F02877" modified="2025-10-08" version="1">MTIRYPNFTPEVMLSAPRRSTAIPNPSGTKLLYSISTYSFHSHRRTAEIRVFDIESRKDTCLCGAPGYREPLWLNDTEVLLLGSVVDGVTSLNVIDIRTSGAVTEISRASGTLDNLRVRRLSDTEVAIAVSAPTTPQGKLYTPSHAKPRYSTAKVYTQLFVRHWDTYNTENKNSVWYGLLRKSGTRYTLASPGLTNALEGTGLECPVPFAPGTNHFDLGPSGIAFVAKDPELNPAMYTKTDLYYVPLKSYTEKPPQQKPSIVHTEKLQGYSASPTFSHSGKKLVFTRMRSKQYESDKRRLMIIPDITDLTNLHEFYSSENGQGTLDLSPDELLWSHDDEHIYFTAESFGKVLLLKVPADPTTTKHPIVLYNHDSVINAVVLENSGHILVSSSSLIESMAYYIVKAPSTATASEKPQVGLLFSSTSNGALFGLSRKQCDEFWFKGAENVEVHALVMRPANFNETQKYPLAFLIHGGPQGAWNDAWSTRWNPALFAQQGYVVVACNPTGSTGYGQAFTDAIANSWGGRPYRDLECCMNYIAAEMPYVDMQRAVALGASYGGYMINWIAGQPLARRFKALVCHDGIFSTHTKWATEELFFPYHDFGGAPWDPESTYRQWDPAQFHGRWETPMMVIHNELDYRLPISEGLAMFNVLQARNIPSKFLTFPDENHWVLKPENSLVWHKEVFSFINEHAKVKTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM26</accession>
    <name>A0ABR3ZM26_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="434" mass="48664" checksum="C7D8CA76F7511713" modified="2025-10-08" version="1">MSTALVTRTSAVLDIIAATSCRDLYRPRNDALQRTIRPSSLRVRQISITRQRYATDASKKKPKKRYIIPTAVSTPPRRDPYMFPKAREWATAIGIGTPVSLRPFKLVLPPLLRGVGFAPKYSPLPTIRGTDMPVYFSALEHPMSAYHMLKYERKLATHSLFLYIHVGVTAQPVVRNYVERWVRDAIWAAMRERGYSNTGRVLQAGEMPPGITPPNQDMCGTLLVNITNPLKVVTLKRSQSLEIGRHVVQTVLRELVAQAHPNRLLQPVQFPADFLPHYKKKALLAQIEKEWEEESKGMPRVKSVEEKLADAIADKGKFYNTSKSSESQTASGAVSILKRSMKAIATTPLGENISSTQKTRLAEEAKLVSEIKKLWTNRPGTSDTSASKPVAADSKSAPAPKQPPVWNADEIERRWNEAGTPKTVRRGWKPRNIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM42</accession>
    <name>A0ABR3ZM42_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glucose N-acetyltransferase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000297</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050587">
        <property type="entry name" value="GNT1/Glycosyltrans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11183">
        <property type="entry name" value="GLYCOGENIN SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="346" mass="39220" checksum="D61B9792E0191F6D" modified="2025-10-08" version="1">MESPPQEEPTHDSPVPGSVSTPPEVDSPADPLRVPEWSDPVVPEGADWSRFAIVQYATNLDYLCNSLMIFDSLRKLNTKADLVLLYPEDYAPVNIKSPESKQEKLIVKARNEYGVKLHPIKVIRRAVSDSTWAASYSKLISFNLTAYDRVLSVDSDGLVLKNLDELFFAPPATVAAPLAYWLRPEEDVLSSQMLLIRPSTEELARVSQAIDAADDSDYDMEIINNLYRQTALILPHRPYDLLIHEFGILSNAEHARYLSNADNVPSDDAVLEPWDPLLAYNEAKYLHFSDWPMPKPWKRPTRAQTLTFQPKCVEKHGTMVDCTAQRLWVGFYEEFLVQRSRVCLGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM59</accession>
    <name>A0ABR3ZM59_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Plasma membrane sulfite pump involved in sulfite metabolism</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SSU1_1</name>
        <name evidence="9" type="ORF">Cpir12675_000595</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09318">
        <property type="entry name" value="TDT_SSU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.150">
        <property type="entry name" value="Voltage-dependent anion channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004695">
        <property type="entry name" value="SLAC1/Mae1/Ssu1/TehA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051629">
        <property type="entry name" value="Sulfite_efflux_TDT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038665">
        <property type="entry name" value="Voltage-dep_anion_channel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31686">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31686:SF1">
        <property type="entry name" value="SULFITE EFFLUX PUMP SSU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03595">
        <property type="entry name" value="SLAC1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="275"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="344"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="393" mass="43192" checksum="FC129EF6858A8A6E" modified="2025-10-08" version="1">MSVSAPARSNTSADSNTCAGGQTELCETRRTAEEAGWRRVVRNFTPSWFAATMGTGIVSILLHELPYNAYWIQVLSWVFFALNVVLFATFSFICIVRFSLYPEIWSVMIMHPVQSLFLGTFPMGLSTIINMMTYADLHLPSMHFHKPGLHTITGGIMLPIVPTIVVSSTGALVSSILPSASHAQLTILTSYVLWGLGVSFSMVITALYFHRLTVHSLPSRELIVSVFLPVGPLGQGGFGIQRLGREALRVFPQTGLLHDVLSDGSTDGSLIAGRFFYLAGLLMGLIMWGFGLLVLSNALLSIALTKKFPFNMGWWGFTFPIGVLATCTGQLAKSLDSTFMRMVTMVLSLAVVALWTVVAIKTLWLAYTGEIFYAPCLKDLRNKQDRGEESKTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM94</accession>
    <name>A0ABR3ZM94_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Formate dehydrogenase</fullName>
            <shortName evidence="5">FDH</shortName>
            <ecNumber evidence="2 5">1.17.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">NAD-dependent formate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">FDH1_1</name>
        <name evidence="9" type="ORF">Cpir12675_000454</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>formate + NAD(+) = CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:15985"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.17.1.9"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.1.9" evidence="2 5"/>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008863">
        <property type="term" value="F:formate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05302">
        <property type="entry name" value="FDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03210">
        <property type="entry name" value="Formate_dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033689">
        <property type="entry name" value="FDH_NAD-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005750">
        <property type="entry name" value="PRK07574.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42938">
        <property type="entry name" value="FORMATE DEHYDROGENASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42938:SF9">
        <property type="entry name" value="FORMATE DEHYDROGENASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="7">
        <location>
            <begin position="36"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="8">
        <location>
            <begin position="129"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="175"/>
            <end position="176"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="231"/>
            <end position="235"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="312"/>
            <end position="315"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="358"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="5">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="5">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="364" mass="39745" checksum="52471737532003E7" modified="2025-10-08" version="1">MVKVLMVLYDGGKAAKEVPDLLGATENELGLRPWLESQGHTLVTTSDKEGENSVFDRELGDAEVIITTPFHPGYLTAERLAKAKKLKIAITAGIGSDHVDLDAACTTNGGITVAEVTGSNVVSVAEHVLMTILVLVRNFTPAHEMVVRGDWDVAEVAKAEYDLEGKVVGTVAVGRIGERVLRRLRGFDCKKLLYFDYQPLSAEKEKEIGCCRVESLEEMIAQCDVVTINCPLHASTRGLFNKDLIAKMKRGSYLVNTARGAIVVKEDVAEALKSGHLAGYGGDVWFPQPAPRDHPLRYATTPFGGGNAMVPHMSGTSLDAQKRYAEGTKSILESYFSGKHDYRPEDLIVHQGHYATRSYGKEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMI1</accession>
    <name>A0ABR3ZMI1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">tRNA-dihydrouridine synthase 2</fullName>
            <ecNumber evidence="12">1.3.1.91</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">dus2</name>
        <name evidence="12" type="ORF">Cpir12675_000364</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs. Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a 5,6-dihydrouridine in mRNA + NAD(+) = a uridine in mRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69851"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="8">
            <dbReference type="Rhea" id="RHEA:69853"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 5,6-dihydrouridine in mRNA + NADP(+) = a uridine in mRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69855"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="9">
            <dbReference type="Rhea" id="RHEA:69857"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.91" evidence="12"/>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102264">
        <property type="term" value="F:tRNA-dihydrouridine20 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052582">
        <property type="entry name" value="tRNA-DUS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45936">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(20) SYNTHASE [NAD(P)+]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45936:SF1">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(20) SYNTHASE [NAD(P)+]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="11">
        <location>
            <begin position="89"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="402"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00045934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1901674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="451" mass="48913" checksum="44F542210981BFDF" modified="2025-10-08" version="1">MVTEVKKVPIPPRGVDYRGKLVLAPMVRSGELPSRLMALHYGADLVWSPETVDRAMIGTTRLVNERTGTIDFVRRPSNGAKDKSTNTEAKDSIIFRLHPEREGKKLIFQVGTADPERAVEAARIVAPDVAGIDVNAGCPKPFSTSGGMGAALLKTPEKLASILEALVKDITPEFGIGISVKIRLLDDPENTEALVRRLCATGITGLTIHCRTTPMRPRQPAIRSQLSMIRRVCHEAGVACLVNGDVLNRDQMANLVEEFGVDGAMIARAAEENPSCFRTEADGGMAHWSEISREYLRMALEVDNKFTNTKYLLAQMVPGKEHETYSGLIRARNYLQLVDAFGYAELRTDAEDLDAHLGLSERETGKIDRHRLEKINKINHYSQAADTVAAAAGKSAVVREQERQKKKSAFSERGVSSAASARGNKASGAATGVGTVTVAASAAKETSPMPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNS9</accession>
    <name>A0ABR3ZNS9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Oligosaccharyl transferase subunit ost3/OST6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">OST3</name>
        <name evidence="11" type="ORF">Cpir12675_000182</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the OST3/OST6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021149">
        <property type="entry name" value="OligosaccharylTrfase_OST3/OST6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12692">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12692:SF0">
        <property type="entry name" value="GH11935P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04756">
        <property type="entry name" value="OST3_OST6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045399030" evidence="10">
        <location>
            <begin position="20"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1902075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="333" mass="36384" checksum="2CDEF99EC892AA91" modified="2025-10-08" version="1">MRLLTTLVSGLTLVAGALSAKSKGHFSDPFTTFHETAVKAAAPVKLNTALYNELTASSRDYSVSVLLTAMDPRFQCQLCREFQPEWDVLGKSWAQGDAAGKSRHILATLDFNDGREIFQQLGLSTAPVLLHFHATKGSHAKASSDPVRYDFSTAPQTAEVVHGWISRHLPGRPHPAIKRPIDYVSLAVNTILVSGSLTLALVMWPYAIPMIQSRNLWAATSLIAILIFTSGHMFNHIRKVPYVAMTRDGGISYFAGGFQNQLGLETQVIAALYGILSFCSISLAIKAPRIASPTGQRIAVVILSAVILVVYSLLMNIFRIKNGGYPFRLPPFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPS9</accession>
    <name>A0ABR3ZPS9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Selenoprotein O</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_000074</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00692">
        <property type="entry name" value="SelO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003846">
        <property type="entry name" value="SelO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32057">
        <property type="entry name" value="PROTEIN ADENYLYLTRANSFERASE SELO, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32057:SF14">
        <property type="entry name" value="PROTEIN ADENYLYLTRANSFERASE SELO, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02696">
        <property type="entry name" value="SelO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1902174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="654" mass="72570" checksum="23300010F9B9E609" modified="2025-10-08" version="1">MTTSPLHSQLSSRAPRLSIGELPKSWTFTSKLPADPKFPSPKASYETPRHHITPRPVHESLFSYVRPEPAESPELLAVSPAALETLSIAPESVASLEFLNTVSGNLLHGWDDKSVLDGTTGSTSNTANTQYPWAQCYGGFQFGSWAGQLGDGRAISLFETTSPATGQRYELQLKGAGLTPYSRFADGKAVLRSSIREFLASEALHALGIATTRALSLTKLPHASAARETIEPCAIVLRFAPSWIRIGTFDLPRVRQDYATVRLLAEYVAEEVYGGWEALPGRLAETEAPSSAPLEEPCLGVAAEETEGSESLAQENRFARLYRAIVRRNAAACASWMVYGFMNGVLNTDNTSVLGLSMDYGPFAFIDVFDPLYTPNHDDITLRYSYRNQPTIIWWNLVRLGEDLAPLIGAGDKVDQINLHTHDDLLKHQEDIVPRAEALIGQAGKEYKAVFTAEYRRLMLRRLGLRDSLTHADADIAKFLPDMLDVLAACKLDFHQFFRTLSSTPLSAFVSETQNEVDTMSVVPETASRLFDVAGLVPEDARIKLAEWLSQWGTRVAAEWPTVADSERQQAMKKVNPNFVLRSWILTEIIDRVQKDSDTDVLRRAMHMALHPFEDEWTGRIFDGQVYQGDKAEEERWTGPVPETKVGMQCSCSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ34</accession>
    <name>A0ABR3ZQ34_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Membrane insertase YidC/Oxa/ALB C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_000314</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the OXA1/ALB3/YidC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20069">
        <property type="entry name" value="5TM_Oxa1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028055">
        <property type="entry name" value="YidC/Oxa/ALB_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428:SF66">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEIN OXA1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="OXA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02096">
        <property type="entry name" value="60KD_IMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="332"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="363"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="Membrane insertase YidC/Oxa/ALB C-terminal" evidence="11">
        <location>
            <begin position="203"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1901624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="518" mass="56568" checksum="4648160080EA92D7" modified="2025-10-08" version="1">MLPSRGAVQSLATARLTSQATLRPQNVRSFGTASLRRTTTNSLHPHSTAMLSHRLRNSSSVLSASLMTTGSVVSGSRAFSWRFWQRSKPAEPAATTDATTDATTDVTTIAATATPADAAASSATATSEPTSAADAVTAATTTDPTVTSAAGGIDSSLLDLETILNMPETIGYLEKLGLNFGWGPSSLVQWLLENVHVYSGLPWWGTIFVAQLIVRLLLFKPLLLSHETSTRMQVLRKTNPEYEAALRDFRDGLQRAQTNPRCKEEAMLARQTYLSIEKEHGIRKMNMAWGMLQIPVGIGFYRVLNAMAEIPVPALESGGVAWFHDLATADPLYILPLAGPAMMLAAMTANAKFMPAEQRKSTKVMAMVLMPVSAIFTSWLPSAVQWYFFCAALFGAIQNVFIAQPWGRRILGLPAMPEITASNPVTTTLTSVPSNANYQAPRTANIEPEKAQDIVSELKGGFNTMLQKGKDTMDRRTRKQEISDKLDREAKIQGESWEALRARMAAKEKEARSRGRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ41</accession>
    <name>A0ABR3ZQ41_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_000075</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19120">
        <property type="entry name" value="AKR_AKR3C2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044494">
        <property type="entry name" value="AKR3C2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF3">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="20"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1902175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="295" mass="33023" checksum="792C85F1D6601110" modified="2025-10-08" version="1">MSLPPFKLNNGFSIPALGYGLGTANFKSTPGDLDEATVNATVTAIKTGILHLDGAELYGNEEELGQAIRNSGLPRSQFYVTTKLFAEDPAPAEQFLRQSLQKLGLDYVDLYLIHQPFAANDDPNILQTRWAELEALHDAGLTRSIGVSNYLKSHLEPVLATARIPPAVNQIEFHPHLQHGNLLEFHRKHGILTQAYSPLTPLTHEIPGDSAVKLIWQRLAGKYNVSDSAIGLRWVLDQGVLPITTSKRKERLESLLEDLPRFKLTEDEISEINKAGETVHYRVWWRNKIANDDHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRA0</accession>
    <name>A0ABR3ZRA0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">2-dehydropantoate 2-reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000119</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051402">
        <property type="entry name" value="KPR-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708:SF26">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708">
        <property type="entry name" value="PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketopantoate reductase N-terminal" evidence="1">
        <location>
            <begin position="11"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Ketopantoate reductase C-terminal" evidence="2">
        <location>
            <begin position="156"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1902014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="292" mass="32090" checksum="C53BBAE82F95EADF" modified="2025-10-08" version="1">MQTHSFGDYHFSPTAVYPSVQAAATDSSGTWDYVFVATKALPDVNDDSDTIAPLISRDTVIVLIQNGVGVEAPYRARFPGTPIVSAVTVISAEQKSPGVIKQNRWTRISIGTYTDGWGTADDVLARKGDAAVRALAKWWGDFGGIKDVDVHDEVDLQMVRWHKLCINSAMNPSAVLCGGRGNADMASDPELRRHLRGVMEEIRAAIPSILGRGFPEHLAKPEAILKSTDRNTGARPSMLLDWEAGRPMELEVIMGNPVRIAREKGVELPRLQTLYALLRSLQEMRKNDKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFU9</accession>
    <name>A0ABR3YFU9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DNA replication licensing factor MCM4</fullName>
            <ecNumber evidence="11">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">CDC54</name>
        <name evidence="14" type="ORF">Cpir12675_006651</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="11"/>
    <dbReference type="EMBL" id="JAWDJO010000342">
        <property type="protein sequence ID" value="KAL1887200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17755">
        <property type="entry name" value="MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008047">
        <property type="entry name" value="MCM_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF66">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21128">
        <property type="entry name" value="WHD_MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01660">
        <property type="entry name" value="MCMPROTEIN4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 11" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 11 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 11 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="13">
        <location>
            <begin position="566"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="297"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="13"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="83"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="150"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="304"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1887200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="986" mass="109313" checksum="835E37D9C1860722" modified="2025-10-08" version="1">MSNNDNTPRRSGRNSSLNPRQPNSPLASTPSSAAETPRLPSHMASSPMFYQSSPAPLGANPSSPLAVDSQMTDSQDMGDRTPRASQMRTIRDSSPVNYPASSSPGRSIRQQSELHSDMSGMFVSQGSDYGLDSRRPARTEPPASFGQQPRPVPGSTPFIPPSTPGQTPLLNSEAENNNVGNNALIWGTTINLELTRSRVHQFLMEFTPRMRMIRDGMTDAEIAETPGASDYCYRDDMFLMLEMGVQTLPVSISDIKCFPGFESLAQQLIHYPQEMVPIFDQGIRDIMVSLAAQEDQKRARERYQNQANMPAATPNSELDSEFASTPVPSHHNRHQKSMEEIAQEAQYQVRMYGMNEISNMRSLDPSDIDKMITVKGLVIRATPVIPDMKTALFKCDVCGWCHSAYNERGRITEPTECPNVNCNSKNSMQIQHNRCTFEDKQILKLQETPDDVPAGQTPHSVSVMMYRDMVDCCKAGDRVVITGIYRASPVRVNPTQRAIKSVHKTYVDAVHAQKIDKKRMGIDQSTLILDGDDNQPTEVNPSITETRKITPEEERKILEASQKPDIYEILARSLAPSIYEMDDVKKGILLQLFGGTNKTFTKGGNPRYRGDINILLCGDPSTSKSQMLGYVHKIAPRGVYTSGKGSSAVGLTAYVTRDPETRQLVLESGALVLSDGGVCCIDEFDKMGEATRSVLHEVMEQQTVSVAKAGIITTLNARTSILASANPIGSRYNPNISVPQNIDLPPTLLSRFDLVYLILDRPDDKTDRRLAKHILSLYLEDSPDHAPTENEIMPVEFLTMYISYARSNVHPKITDAAATELTNSYVEMRKLGQDVRSSEKRITATTRQLESMIRLSEAHAKMRMSPEVTRDDVFEAYRLIKSALKTAATDSQGRIDMSLLTEGTSSADRRMKQDMKKAILGVIDELTASGNTVRWAEVLRKLSESVNVQVEASDFNECMRALEMEGAMVVMGEGARRSVRRTTGAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGK9</accession>
    <name>A0ABR3YGK9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006823</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000385">
        <property type="protein sequence ID" value="KAL1886948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="181"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1886948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="300" mass="31368" checksum="C51DEB6571D089E3" modified="2025-10-08" version="1">MAPIRSSAPVSEKSGLPLPAIATSTSPFPTPTSLSQRRRSFFTFTMRASLIALFGLIYLGAAFAPRVPCNHDLSGDDQSHGHVDAVANHADLPDGPAVDESAFSSMLNSVSPEHLHKLLHSNLPGMYRHGVYESDRHAAEMLHRTDARLATSLVRMAKRQSNSSSVITEPSSTEQTTQLPTETDTSSQAETASESTPTPTTTTEENSDTTITEAPTTLTSTTPTLVTSESLTTFTSTDAAGNVQVITSTAMVVVRPSSTSSSASATSTPDLQNAAPRPAAGAMVVPAVLVMAAVGGFLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHF9</accession>
    <name>A0ABR3YHF9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_006499</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000310">
        <property type="protein sequence ID" value="KAL1887564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF666">
        <property type="entry name" value="VACUOLAR AMINO ACID TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="353"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="388"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="433"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="473"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="497"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="538"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="571"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="618"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="660"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="683"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="713"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="8">
        <location>
            <begin position="356"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="27"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="246"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="308"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="55"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="168"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="341"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1887564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="757" mass="81955" checksum="AEB4797FF2937F83" modified="2025-10-08" version="1">MTSPSGRLGTSPSATALPDQNRLENAALLSSSAPRADATARLASPIPFTAPGTPPRQSGLANEVQRSGSATPLVGSIGGPSSVGPGISALAAALSGPVGASPPRFGTPPIRSATPPMQSNSPFVQGQMSNYGSFDSRPRGLSGTGVYENPEIVRRHLVQPTDAVSETSSRDGGKGKSAVEDEQEFSSLRLQGGDVTRPIYKWAEEAEAKQRVQRSKSFNALRPDPVAAELDINTIKVPGGFRRNFVRRAGGPSTAADSADGGEAGDGLSPNQPKLLTSSFLEFLTIYGHFAGEELEEDDEALRPGEYFSSGAEDDAFDGSYDGSESEDEERMEDSALLTPSRRKRRRKSRGGSGNNSTTGAALLLLKSFVGTGVLFLPRAYLNGGMLFSNVVLLLVAALSYYCFVLLVTTRLKIAGSFGDIGGILYGKWMRKIILASVVLSQIGFVAAYIVFTSENLQAFILAVTDCKIHIDISWLIIMQMVIFLPFSLLRDIGKLGFTALIADAFILVGLAYLFYYDILTLSTKGLADIVQFNEKDWTLFIGTAIFTFEGIGLIIPIHESMKQPSKFPKVMFVVMVIITVLFTTMGAFSYAAYGSKTETVVLLNLPQESRMVNTVQLLYSAAILLSTPLQIFPAIRITENSLFTKSGKYNPYIKWQKNVFRFFLVALCALIAYCGADNLDKFVALVGNFACIPLVYIYPPMLHYKAVARSRLWKASDVVLCCFGIIAMAYTTYQTMSAWASAPPVPETPRYCDRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHH3</accession>
    <name>A0ABR3YHH3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">8-oxo-dGTP diphosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PCD1</name>
        <name evidence="9" type="ORF">Cpir12675_006417</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000297">
        <property type="protein sequence ID" value="KAL1887785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03426">
        <property type="entry name" value="NUDIX_CoAse_Nudt7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045121">
        <property type="entry name" value="CoAse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992">
        <property type="entry name" value="NUDIX HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992:SF24">
        <property type="entry name" value="PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="8">
        <location>
            <begin position="142"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="61"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="434"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="445"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1887785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="460" mass="50607" checksum="1CA1BB3E3B2954A4" modified="2025-10-08" version="1">MGQTTAPAPSTAAKVAASEADVVASPFASKEIPKHQGASHVLAPASDKSYDKSQEYLFTGASSSHVQELNKKEQVKDDKERESYKHQVDLEAITSPKGSSESSEYWDPHSMSLLSTKSLAAVARLRQYRPPAFPLWNQLPASRRAAVLILLYPDRVGDLRVVLTMRASGMRNFGGHAAFPGGKADTTSESPYEIARREAWEEIGFPETNDLLPKSYDIEFLCHLPHSLARTDVVVRPCVALLSRRPPPPATSSTEAVARSLSSASQAAVSDTLRPTPSAGEVAAVFSGPFHNFLLSHDEAPSPALSTRAQLPPGPWYEGGWGEHVSGAPWRIHNFYVPITNQRVTKPAPVPVPSMQKWRETVRRPDVLEEHWGRYKVWGFTAKILVEAARVAYDESPQKHLEAADHLGDEALVLDAASMGRFYDRKRQSESLVGAQPGLRGNSHMHRDWRDRTGGQEAKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI47</accession>
    <name>A0ABR3YI47_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000302">
        <property type="protein sequence ID" value="KAL1887690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="120" mass="12905" checksum="465962AD4B7C08A6" modified="2025-10-08" version="1">MPVSLDSERPIMAPSARNSIRYSTFSMAPSIALSVDSTATTVPTEITTIASGLARMENKALSSQRVTLSEERTSYMAKLALGAKLDRALDRRMSGQDAVMRPRSGTLPENNKLSEKTAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI52</accession>
    <name>A0ABR3YI52_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_006340</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000284">
        <property type="protein sequence ID" value="KAL1888006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029:SF10">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111352">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="224"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="281"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="336"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="382"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="9">
        <location>
            <begin position="34"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1888006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="461" mass="49240" checksum="FA5DD031D22792C1" modified="2025-10-08" version="1">MSLEYNGTEGVADPGYSTGVADLNLFYEPADLCWVMTSSALVLLMIPGVAFFYAGLARRKSALHVLFSVMLVCCVACFQWFFWGFSLTFSSESSSIFLGNLANFGFRDVLAQPSGPVPQILFALFQGMFAMITPALAIGAITDRGRVLPAVVFTFIWCTVVYDPVAYWTWNSQGWLFEKGSLDFAGGGPVHMSSGIAALAYSMMLGRRTGYAKMSGLPYRPHNVTHIVLGTVLLWVGWLGFNGGSALASNLRAIMACFVSNLAAAVGGITWCLLDLRIEKKWSCVGFCSGVVAGLVAITPGAGFVTPWAAVIFGIVGATVCNFSTKLKFLVGIDDALDVFALHGMGGFIGNVLTGIFADKQMAALDGTVIEGGWVEGNYKQIGWQLAGCAAILGWVFSITCIILFVMNLIPGLSLRVSAEEEEMGLDDGQLGEFAYDYVEVTRHISGNGLGLSGASTVEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIC9</accession>
    <name>A0ABR3YIC9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein BFR2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">BFR2</name>
        <name evidence="6" type="ORF">Cpir12675_006478</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AATF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000307">
        <property type="protein sequence ID" value="KAL1887622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025160">
        <property type="entry name" value="AATF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039223">
        <property type="entry name" value="AATF/Bfr2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012617">
        <property type="entry name" value="AATF_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15565">
        <property type="entry name" value="AATF PROTEIN APOPTOSIS ANTAGONIZING TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15565:SF0">
        <property type="entry name" value="PROTEIN AATF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13339">
        <property type="entry name" value="AATF-Che1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08164">
        <property type="entry name" value="TRAUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AATF leucine zipper-containing" evidence="5">
        <location>
            <begin position="275"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Apoptosis-antagonizing transcription factor C-terminal" evidence="4">
        <location>
            <begin position="458"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="546"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="34"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="82"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="115"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="127"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="172"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="211"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="547"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="575" mass="65188" checksum="141089C65D90B4FE" modified="2025-10-08" version="1">MKTKLRGRARQFAQLEEKPKTDYDPEAENVPSENENDDGESEDENAGTEHYVQVGKSKLRKSEGLSLGHNYRGTRVSRKAFEEDDNDLPQDDSDDSDDSEENDEEEEFDDPDMADLEKDQARITNDELIDSDDAFVESDQEFTEKFIFRGSSKPKSTTNSRKNRPKAVDFMPESDQDGGEEDFQDAQEELDDEDDDEVGGSKIVVDGERSEESDDFGSGEDDDSEEDEDDDRDDEEDEEGEEDEDEDEDEEDKTTNRNFNANDHLSSLSAAAKQEALKGMAVRGQRKLFDGLLNFRIRLQKALVSANTLLIADQDTESTASDEDAAEQAAIQLWNTLDSIRTDFTNSAVKGSQKRKRQIDSSTATKSIWGFMQEDEAESLKYRRVTLDKWSRRVGPSAVASRDRLKSTNNSICVVLDEQLSEPSRLIKRTQIPRSCAPAHAAKKISEDTQIYDDADFYQLLLKELVEQRTTETDQAAGTAVATVRWAAMKEAKTRKIVDRKASRGRKLKFTVHEKLQSFMAPEDRRQWEEEAVDRLFNTLLGQQVALDEEDEQSNAEDEDAEIDAEEEGLKLFRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIL1</accession>
    <name>A0ABR3YIL1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000293">
        <property type="protein sequence ID" value="KAL1887855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034772">
        <property type="entry name" value="CPSF6/7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23204">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFIC FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="222"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="258"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="412" mass="42482" checksum="BFCCBB928F113CBC" modified="2025-10-08" version="1">MDDQNLDIDIYGDAHDDYGKPSDSNVDEAMQVDATAAAGPTGISATGSTIVTDSLTGLTGVAGPATNEAKANIPRKPDIDPTATSAVVVSDLNWWSTDDDVRGWAQAAGDECELKDITFNEHKVNGKSKGQVYVEFFTPQAAATFKQHIHTMRNSASAPLSGKHFSVIFSNPHINPFRTRPKDGLSRNQKDGNNNHGSNTNNNSNNRMGAGSSYDRSNNQMGANNPQGPYNNYGNNSNNGWHNNNRVGFGGRGHHAQNNNFNRYNNNNNHGGSGGFSQGGYTGGYSNGRGGGGNMMGMNNVRGGRTGGGMNGLGRGGVGANNMGMGNIGGPIGGMGMGMGGPMNGAMGSMMGGPMPMMGGMQGFAQMNFSPTGFFGGGGGGGGGGGGAGPGNDGHQPDWASNPHGTKRARPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIR2</accession>
    <name>A0ABR3YIR2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription factor Iwr1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_006311</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IWR1/SLC7A6OS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000280">
        <property type="protein sequence ID" value="KAL1888078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040150">
        <property type="entry name" value="Iwr1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013883">
        <property type="entry name" value="TF_Iwr1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28063">
        <property type="entry name" value="RNA POLYMERASE II NUCLEAR LOCALIZATION PROTEIN IWR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28063:SF1">
        <property type="entry name" value="RNA POLYMERASE II NUCLEAR LOCALIZATION PROTEIN IWR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08574">
        <property type="entry name" value="Iwr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription factor Iwr1" evidence="3">
        <location>
            <begin position="304"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="45"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="240"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="354"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="252"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="269"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="463" mass="50568" checksum="BE78B6AA185B7BF4" modified="2025-10-08" version="1">MARPPEVIRIKRKRDDETPLTFLELDTDGNKRARSASNWVYKRRIPKAPLGASAAGPGDRPASSASNVRPQIQASAPGDELLWEKQLQSGGAPTTSAAPLRNEKTNDDVADELQRTFHISKADTERLQSYPSQSSLSSMAAKRRRNTVVFVERNMKKMRAVGGAGSGVASPLGSPFSLHIDDQSGVDVPVPATPSTQQRRPLAIPHGRRPLVERPIVHVHDMDKMASVMDAWAREVVVPTEPQAEPPSNAAPKHKGPVSRYKPKPKPKPAAAPAAASARSAAAAVPTPVTTSITLPTAPDDDDNDYVEEEYHIMDPRAVPTDVPRHLIGRLVIGQDEQEYFYEDRNTQLLGYESDESDENAENHYGNDYPDQELESDSDLGNGNDRIWGIEAGFNGDADGIDDNDDIAMSDYEDENWMDVHAGGTGGGSYSETGKEGNHENMDAKLLERIRRFNAGVNRHGGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIY8</accession>
    <name>A0ABR3YIY8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ATP-binding mismatch repair protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PMS1</name>
        <name evidence="6" type="ORF">Cpir12675_006569</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000325">
        <property type="protein sequence ID" value="KAL1887389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16926">
        <property type="entry name" value="HATPase_MutL-MLH-PMS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03484">
        <property type="entry name" value="MutL_Trans_hPMS_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="entry name" value="MutL, C-terminal domain, dimerisation subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.100">
        <property type="entry name" value="MutL, C-terminal domain, regulatory subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="MutL/Mlh/PMS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014790">
        <property type="entry name" value="MutL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042121">
        <property type="entry name" value="MutL_C_regsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00585">
        <property type="entry name" value="mutl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073:SF52">
        <property type="entry name" value="MISMATCH REPAIR ENDONUCLEASE PMS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01119">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08676">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00853">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118116">
        <property type="entry name" value="DNA mismatch repair protein MutL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair protein S5" evidence="5">
        <location>
            <begin position="217"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="MutL C-terminal dimerisation" evidence="4">
        <location>
            <begin position="866"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="378"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="471"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="644"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="754"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="821"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="378"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="430"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="472"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="491"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="573"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="583"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="650"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="662"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="694"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="821"/>
            <end position="834"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1887389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1129" mass="123554" checksum="9BF2532A90DEDF36" modified="2025-10-08" version="1">MSTIKAIESSTVHKIQSGQVIVDLCSVAKELIENSIDAGATSIDVRFKNQGLDSLEVQDNGSGISPENYAGVGLKHHTSKLSTYEDISNLNTFGFRGEALSSCCALSKVTIVTCRAEDAPKGAKLRFKQSGVLEDTSMVAAQKGTTVIVQDLFYNLPVRRKELERNIKREWNKLISLLNQYACIQTGLKFTVSQQPNKGRKIIMFSTKGNANTRDNIINVFGAKTMAVLVPLDLSLELKPTVPALATGATSQNSPNIVKVKGHVSRPAHGEGRQTPDRQMFFINGRPCGLPQFAKVFNEVYRSYNSSQSPFILADVQLDTHLYDVNVSPDKRTILLHDQGPLLDQLKETLAELFAKKDYTVPAAQLWSIKKSAVSSATNARQESSAPPSRQPFLRTQASLSSQAGSDETPSRRPSALKTQQKRSAHSSSDEDDENEDNDEEDSSQQASAKHLTPVSSNDILSSLPAFVAAAQRQTQSSPSQKMLERLQQKAMAQNKAQESSGKFTTATSILKEQELEELENQKEVDESESDLEDVIHDPSVPRPVRDFHAQLARQARKGQDNQQSTKSHSRQDDEDSHDDDELFVRQEEPRNDDPSDDSDDNNKVITVIAKKRNSKSAPLVQIGGTFKRPSDVAVISIGNNTVTRSIGHSSSRTPRSTATRIQPSRLSNTPSFGGRLAEMFALQKTKQSNRDEIEGEEENGDEMGEDQEEQTEAVSSSMLSRKRKTPATELDADLALDTSGDIRLLDVDMSEDDQLANDNDSTKEATAFQGESSGLAHNTASAARALKGPAKKDSTVSLVQHLKISEDSLRGNLAALKTSVTTHEASRPSQPVETPNAEDGGLEAPGAEEKLSLTISKGDFGRMKIVGQFNLGFILAVRSAAIPDNDADDRTVDGSNTKRQDEVFIIDQHATDEKYNFERLQATTIVQSQRLVNPKTLDLTALEEEIVLENRAALEANGFDVSVDISGESAVGSRCQLLALPLSRETTFTLTDLEELISLLGDHEASVLPASLSLGSSGSSKESTVKSALPLSAAMAASIPRPTKVRKMFAMRACRSSVMIGKALTQGQMETLVRHMGELDKPWNCPHGRPTMRHLCSLGFWEEEGWKEAQGASWIDAEEEYSWREYLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ81</accession>
    <name>A0ABR3YJ81_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Peroxidase</fullName>
            <ecNumber evidence="14">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">CCP1</name>
        <name evidence="16" type="ORF">Cpir12675_006332</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2 Fe(II)-[cytochrome c] + H2O2 + 2 H(+) = 2 Fe(III)-[cytochrome c] + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:16581"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.11.1.5"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Forms a one-to-one complex with cytochrome c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion intermembrane space</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="14"/>
    <dbReference type="EMBL" id="JAWDJO010000283">
        <property type="protein sequence ID" value="KAL1888015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004130">
        <property type="term" value="F:cytochrome-c peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00691">
        <property type="entry name" value="ascorbate_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002207">
        <property type="entry name" value="Peroxidase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF58">
        <property type="entry name" value="CYTOCHROME C PEROXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00459">
        <property type="entry name" value="ASPEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9 14 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 14 16" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="15">
        <location>
            <begin position="90"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1888015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="352" mass="38961" checksum="128E62231C35E04D" modified="2025-10-08" version="1">MASVSRQFARSAIQASTRRAFIAAPRQTAQQGRRFYSSEAPKKGSSSLLYLTGAAAVLGGGYFFYNQGAAEPKERTQADYQAVYNEIANRLEEKDDYDDGSYGPVLLRLAWHASGTYDKETGTGGSNGATMRFSPESGHGANAGLKSARDFLEPIKAKFPWISYSDLWVLGGVCAVQEMQGPIIPFRPGRTDGLAAACTSDGRLPDASQGPKHLRDIFYRMGFNDQEIVALAGAHALGRCHTSRSGFDGPWTYSPTVMTNDFYTLLLDEKWQQRKWDGPMQYENKSSKSLMMLPTDLSLIQDKSFRKHVEAYAKNNELFFKDFSSVCLKLFELGVPFTSTSSERMVFKPTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJE0</accession>
    <name>A0ABR3YJE0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chitin synthase regulatory factor 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006358</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000287">
        <property type="protein sequence ID" value="KAL1887953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051726">
        <property type="entry name" value="Chitin_Synth_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430:SF2">
        <property type="entry name" value="CHITIN SYNTHASE REGULATORY FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430">
        <property type="entry name" value="PROTEIN SKT5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="72"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="534"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="646"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="667"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="733"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="771"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="830"/>
            <end position="853"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="874" mass="94074" checksum="20D2A444977BD44F" modified="2025-10-08" version="1">MELPVCYTAIDNPNNNAGGPSLGATFVPGGFDDFYMPPEVVAPSPQRVMPEVPQNMQNDLQRMELEAGGISAPTSPPISGNGAKTPYQSMTSPGILSPAKQPVLEPSNSSSALNDMPNFSPFPKVKGDNLPIGDDEMESTLWNQKDSVLNSQDVQRQIDWSKNVLTWADMSSESAKREPLDPIRSSTPRIEHELRIASVNIINYLADQGHPEALFIRSKWLEFGKFGMRLDKREAFNGYRSSAELGFIRSEYRMGMFYETSPSADMAKAIEHYQRGLGGGDSASTYRMGMMSLLGQHGQVMNYQRGIDLVNQSADTADEDAPQGAYIFGMLIARELPDINLPESLLPIDYARSKWYIERAAYLGFSKAQLKMGQAYELCQMGCDFNPSLSIHYYALAAKQNMPEACLGVSRWFLFGYEGFFVKNEKLAYKFALEAANAKLSTGQFAVGYYNEIGIHVAKDVREARKWYELAAENGNKDAIGRLESLNQQKTLTKKDHETVTLGRIKSQHGSMRGKRPERFKQVSNSMPAVSEDNLAPGQMSHHASPGVSPKVIPGNPQQDNISMPDPSKLSIHDSRPPAFTVNLQGQNPQAPGGSPGSVPYPEDDMQLPNVNPHFSPNARGPVADRPASAFGIRPPSQASPQNQMGRGGSWGNNGPPMNGGMGNNGLAPQQHGSFRQSAGPGMGMNNPVQRPMSAQPPPSQNYGPGPGPNSGRPMSNMNYPGPGPQGHPQQGNFNPRPQSSLPPSHNGSNYDPRLAGGPKPGPVGPSQSGRGAGPRPGGNPGNFVNHPGRVGSAPPSQNRPPPQQGPVSPMGQGHGRPPMSQPPSQAHSMPPPSTTATPPKPAKASTAPPPKGPATFEEMGIPQGKSNGDCVVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJN7</accession>
    <name>A0ABR3YJN7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_006139</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000257">
        <property type="protein sequence ID" value="KAL1888518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF12">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14340)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="176"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="11">
        <location>
            <begin position="319"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1888518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="619" mass="70099" checksum="A3696C39C6781BEB" modified="2025-10-08" version="1">MVSFSDVIAGISPTIKARAAHGTYPADASSTIAPYHSGLTGVNQPMNLLFVDVLWWTLGIMGLIIFGVRVSEITWMHIRQVTAMTSRPEQQNYWKYTQNTWLPSLKQHLLYAPLWNKRHNREFRLSKAGNMGTLPSRLHSLFLAIYILSNIAYMFVLDWTNPNRYAVHAELRGRSGTLAMVNMVPLILLATRNNPLIGLLKISFDTYNLFHRWLGRLCVIEILIHTGAWLYVQTSDGGWSSVGHRFSNELFISSGFIGMFCMVILLITSFSPVRHAFYETFLTCHIFFGGITFAMTLIHCMSAEIGYLPQTSWIIGIICMWFLERLARVCRLVYCNYSGRGYTEAVIEAMPGDATRVTMHIPRYVNVRPGTHAYIRFRDISPFENHPFSIAWVDHHEDSEDLPPAEKHTMVTRANRKHMTTSVSFIIGAQTGFTRQLYNYAATGGGQPCNLAAAFEGPYAGHHSLDSYGHAVLFAGSTGITHQISYLRPVIEGYNNGTVATRRLTLVWIVRDYDALEWIRPWMDTVLRMPNRKDILRIQLFITRPKNPREIVSASSTVQMFPGRPNVPMILHKEVQEQVGSMVVTVCGAGALADDVRMGVRQMQDEGTVVDFVEESFTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJV7</accession>
    <name>A0ABR3YJV7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_006163</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000260">
        <property type="protein sequence ID" value="KAL1888468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="257"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="289"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="320"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="410" mass="45613" checksum="0B00E41B4FD4B96D" modified="2025-10-08" version="1">MELSPPSLTRSPSTPPSTYYRMSSPGAVEQQYRLQSMYSDAGCGIMDSGSSMVHAGWSSPGSTIPSISDAIGASVTPTSMPTSIMPSDYDSFNTYEQQSQNAHAHGEYAQELYHHQPHNVETTSTGGHSPVPSHSSFGTPFMHTTPLPPRIKDESHLEAYSNLSGNRYSPSAIHPTSAAPFISDVYGPPQGYVIDPMQQTPHSQSAQHFYIHPSVPHDPVLLAPAAALSESVLADRRFRLRGRRAPRRLTTKEEANFQCEVKGCGKLFSRSYNYKAHMETHDEKREYPFPCEVTDCTKKFVRKTDLQRHHQSVHMKERNHSCDYCGRKFARKDTLRRHMEDGCSKRFDLGSVDFQADAYDALHQQRLPMAVQPMAHPLTSPPPHHISMGPVGGMIAPAMVPCNQVHTWGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YL01</accession>
    <name>A0ABR3YL01_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2 7">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_006149</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the peptidase C12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2 7"/>
    <dbReference type="EMBL" id="JAWDJO010000258">
        <property type="protein sequence ID" value="KAL1888508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.532.10">
        <property type="entry name" value="Peptidase C12, ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001578">
        <property type="entry name" value="Peptidase_C12_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036959">
        <property type="entry name" value="Peptidase_C12_UCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589:SF29">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01088">
        <property type="entry name" value="Peptidase_C12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52048">
        <property type="entry name" value="UCH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UCH catalytic" evidence="9">
        <location>
            <begin position="90"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="11"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <feature type="site" description="Important for enzyme activity" evidence="7">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1888508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="480" mass="52970" checksum="FFA480FA612F33FB" modified="2025-10-08" version="1">MLSEVPPIATSDDSSPDGSKNIPSNVQLALGDASMDRSPEPPTPTTTISRRHGLRKWPSPTTPDHDIPDGDLLAASLAPLTKKDLEHWKGWIEVESDPAFFNAILRDLGVKNVRAQEVLSLDNLATLGNTIFGLIFLSEYIENDENLKTECDNIWFANQTVENSCATVALLNLIMNAKCANLGETISKFREMTQPLDTITRGKYISQNTFLRSTHNQFASRMDILNADLALDNQTTTDSTGKRMIRNISVASKRQRRNAETSFHYVAFVKSEQEEVWELDGLRWNPVSLGKVGDASVGDSGANWLSLIMPVIESRMESSSSAGFSLLAFIEDPLWPCALEIAKSLATVKVIERHATKQTPSWDITTATPSTPLAGGNDEEALKLYKLTLGDIDSAQPEDQVLATLKHGMNKEGTLELREACIGKVHDALSKWEAQHIQLDAETLSSEERNESFLPAIHEWTRVLAEIDELKMLNTLASAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLT7</accession>
    <name>A0ABR3YLT7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Copper-fist domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_006204</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000265">
        <property type="protein sequence ID" value="KAL1888349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.430.10">
        <property type="entry name" value="Copper fist DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051763">
        <property type="entry name" value="Copper_Homeo_Regul"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001083">
        <property type="entry name" value="Cu_fist_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036395">
        <property type="entry name" value="Cu_fist_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28088:SF9">
        <property type="entry name" value="TRANSCRIPTION FACTOR GRISEA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G13190)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28088">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR HAA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00649">
        <property type="entry name" value="Copper-fist"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00617">
        <property type="entry name" value="COPPERFIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM01090">
        <property type="entry name" value="Copper-fist"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00412">
        <property type="entry name" value="Cu_FIST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57879">
        <property type="entry name" value="Zinc domain conserved in yeast copper-regulated transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01119">
        <property type="entry name" value="COPPER_FIST_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50073">
        <property type="entry name" value="COPPER_FIST_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Copper-fist" evidence="9">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="94"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="274"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="430"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="552"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="101"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="287"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="297"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="325"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="361"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="437"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="454"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="471"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="562"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="586"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1888349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="641" mass="66606" checksum="9561BFB1B09E7DED" modified="2025-10-08" version="1">MPIIDGIKMACVPCIRGHRSTKCNHASERVMVPVRKPGRPLSICPHPSTKPCACGVTAAIPKKSTCSCSPSGSKAEPCTSKSIGTGAGAAALVPASAPNPASDPAPGPGPAPAASSSSISAQNGLPHTHVHNPQSSAVPPTQLASQLRPTNGASPPIKTISAPGSGRIQKAQPPKSTRKYSFDPSVLHRIDVNHTNIVSPVMAFDTANCSPQTQTPIMPLQPQLPPQLQTQQPHLQSLSYNPNPMLSNQASQITVPMMMSMYLPTMSGSMMSQIPGHVTDSPSASPTTTRTTNTNTYISSPHVGQQRPQSIKLESDSRAHEQALSSPSSSPSEAMAPKKSCCNGGGKKSPAVAAKPVRATITPTSMPGSGGQQPPNTAIPATTSSGPGDMHMNAFYSPFAYPPQIGSLIQPLSPEQWRLCMDSHIAAQAHAARNQHETQSQNQTPNPMLNSTFGSLPVQLSPGSLSQSQPPGQPPSQPQPLYHVPPPPPDAQPCTCGDTCQCLGCWWHPYNQTTTDQVMSAYNAMWGDSVFDADPVSAAAVKSPVISAGNGGCCADEDSNRSRSSGGTTNNSNGNSAPAGTHEAQSHSPVSAGGSSIEEQNLSADTFLFVHYPIHGTCLGESVTCPCGDDCECLGCVVHGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMA2</accession>
    <name>A0ABR3YMA2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NADH-ubiquinone oxidoreductase 21 kDa subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_005772</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000215">
        <property type="protein sequence ID" value="KAL1889464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053229">
        <property type="entry name" value="NADH-Q_oxidrdct_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024549">
        <property type="entry name" value="NADH-UbQ_OxRdtase_su21_C_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019721">
        <property type="entry name" value="NADH-UbQ_OxRdtase_su21_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34062:SF1">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 21KDA SUBUNIT N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34062">
        <property type="entry name" value="OXIDOREDUCTASE 21 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G04750)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10785">
        <property type="entry name" value="NADH-u_ox-rdase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12853">
        <property type="entry name" value="NADH_u_ox_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="NADH-ubiquinone oxidoreductase 21kDa subunit N-terminal" evidence="2">
        <location>
            <begin position="14"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="NADH-ubiquinone oxidoreductase 21kDa subunit C-terminal fungi" evidence="3">
        <location>
            <begin position="108"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="185" mass="20636" checksum="07C3364BD44463E4" modified="2025-10-08" version="1">METPTYFPTKAYETDYPLIDSDPHFKRVVGYARPSDYVHGLVAAAFGPGALLFMEKFAPSHVGKGGFAPAMRLAGAVGITGGFLYFYQRSALRFYGATENAREIEMDMREMVSKVKSGQSLYGESQLTPHLQGVAARQSRYSALFMGVIPWFNFVNHNQHGVDTAKYYRQAEKELEEERATKASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMI9</accession>
    <name>A0ABR3YMI9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005797</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000217">
        <property type="protein sequence ID" value="KAL1889397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="9"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="281" mass="31989" checksum="E693830B908E8FAC" modified="2025-10-08" version="1">MTIELSRTAGNTPLILACHFGRPEIIEELVQARANQFALNRAGNNILHEIISYPLPKSPMLCALLDIFDQKLLRELLKQRNHVESGSFTPVHIAFQSLQQICPSNPRNGTRRLFKSEWTQDCIPRFVSLFLSYLSEHFSELKILDASDDTVLHGPIAQSSWRLIDQLAAFRPQLLVRENACGKTPAEAALMKRYAATFVASKSSLESFAFPKNNKKLVYGVRQLLTKPSGWTATVEEKERIWFQAMHVCNSQARTTKMLHLHGSRVQRIWLRESYDADQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YML7</accession>
    <name>A0ABR3YML7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nucleolar zinc-finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ZPR1</name>
        <name evidence="7" type="ORF">Cpir12675_005739</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ZPR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000212">
        <property type="protein sequence ID" value="KAL1889546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1040">
        <property type="entry name" value="ZPR1, A/B domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.420">
        <property type="entry name" value="ZPR1, zinc finger domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004457">
        <property type="entry name" value="Znf_ZPR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040141">
        <property type="entry name" value="ZPR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042451">
        <property type="entry name" value="ZPR1_A/B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056180">
        <property type="entry name" value="ZPR1_jr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042452">
        <property type="entry name" value="ZPR1_Znf1/2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00310">
        <property type="entry name" value="ZPR1_znf"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10876">
        <property type="entry name" value="ZINC FINGER PROTEIN ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10876:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22794">
        <property type="entry name" value="jr-ZPR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03367">
        <property type="entry name" value="Zn_ribbon_ZPR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00709">
        <property type="entry name" value="Zpr1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger ZPR1-type" evidence="6">
        <location>
            <begin position="31"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger ZPR1-type" evidence="6">
        <location>
            <begin position="251"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="366"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="478"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="369"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="383"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="500" mass="55073" checksum="921B276D204ABFD8" modified="2025-10-08" version="1">MAVPTEFQSIGAHAEQTATSDDVQPVEQIESLCMSCHKNGWTRMLLTSIPYFREIIIMSFSCEHCGFHNNEIQPAGSIQSKGTHYELRLTSLADFERQVIKADTATIKFIELDLEVPSGRGQLTNIEGVLAGIIDDLDMGQETRKAEQPEVYAKIEEIIARGKKMLAGEAFPFRMYVDDPAGNSFISPDLKDGVGKWEKHEFLRTPEQNKALGLTASGEQADGTLIGHSVKQPSLTEEGEIALNEVYSFPATCPGCMHPCVTHMKMVDIPHFKQVVLMSTVCDSCGYRSNDVKTGGEIPDKGERITLKVEDEVDLARDILKSESCALECPELDLMVNAGTLGGRFTTVEGLLTQVRNDLHNQIFEAQGSKPTQLSSSAAPVEKLADEKKEGSEKRTREAGDSMAEEQRSTWTKFFEGLDTAIRGEKPFTLVLSDPLASSYVQTLVDPPATDPKITREVYNRTEDEEEDLGLNDMKVEGYENDAAASGEKVADENTMDESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMQ4</accession>
    <name>A0ABR3YMQ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Iron-sulfur cluster assembly protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ISU1</name>
        <name evidence="7" type="ORF">Cpir12675_005831</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 5">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; iron-sulfur cluster biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the NifU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000221">
        <property type="protein sequence ID" value="KAL1889340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06664">
        <property type="entry name" value="IscU_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011339">
        <property type="entry name" value="ISCU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002871">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01999">
        <property type="entry name" value="iscU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10093">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY ENZYME NIFU HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01592">
        <property type="entry name" value="NifU_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82649">
        <property type="entry name" value="SufE/NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="NIF system FeS cluster assembly NifU N-terminal" evidence="6">
        <location>
            <begin position="15"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1889340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="152" mass="16150" checksum="60C672F189CF6597" modified="2025-10-08" version="1">MKPDFEQQNANFCALIDHYTNPRNVGSLNGKDPNVGSGLVGAPACGDVMKLDIQVDEKTGTIIDARFKTFGCGSAIASSSYVTTLVKGKRLEEAAQIRNIDIASELCLPPVKLHCSMLAEDAIQAAIANYKSKRTAFTPSNLSGTAKTLESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMZ6</accession>
    <name>A0ABR3YMZ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_005681</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000207">
        <property type="protein sequence ID" value="KAL1889703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1889703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="277" mass="29038" checksum="0C4E2C1908EC9B45" modified="2025-10-08" version="1">MSPVWLITGASKGLGFALANKILDSGHRVIAVIRNKSSNAEAVATIEGKGGKDTIITAVREAERIFGVIDILVNNTGQSGLAPLEDVSNSEKDVHGMLATNLYGLIYAIQVVIPGMRDRKSGLIINVTSAMGLAGLPGGSLYAATKFTLEGVTECTSKELAVFGIEAMCVEPGAFATAMVVCTKALYSAPYKGTDAGNFLDMVAAGLDKSKLGDPDKAAARIFEYSTRQGAAGALRGKTNRLMLGSDCIESVEKKVEQLSLEFDLNKPIGVITGFDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNQ2</accession>
    <name>A0ABR3YNQ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD-specific glutamate dehydrogenase</fullName>
            <ecNumber evidence="4">1.4.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">GDH2</name>
        <name evidence="6" type="ORF">Cpir12675_005941</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-glutamate + NAD(+) + H2O = 2-oxoglutarate + NH4(+) + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15133"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.4.1.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.2" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000233">
        <property type="protein sequence ID" value="KAL1889039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004352">
        <property type="term" value="F:glutamate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056365">
        <property type="entry name" value="NAD-GDH_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016210">
        <property type="entry name" value="NAD-GDH_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055480">
        <property type="entry name" value="NAD-GDH_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606">
        <property type="entry name" value="GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606:SF24">
        <property type="entry name" value="NAD-SPECIFIC GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23147">
        <property type="entry name" value="GDH2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23152">
        <property type="entry name" value="GDH_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000184">
        <property type="entry name" value="GDH_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal" evidence="5">
        <location>
            <begin position="713"/>
            <end position="978"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1889039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1077" mass="120635" checksum="BD8AEE35CE6F563A" modified="2025-10-08" version="1">MALTLNTTDSTPVDSFPEFCDLTQSPSATMAEVALPRALSKVQQAEGRHPSPQPAHLAMPLAARLNGNGHRTLRSATVGYVAEAFQGKAEQMTEVKSILAKAAMIPSDTIDAQIAWFYKDLGIDDGYFKIESPAIIANHITSLYAAKVASMSRQDRREEIRLDMEDTDHAIYIDTSEPGVSVIDGPRYEERLEAKYLDSSNPNKFRIETFRSPGVLGASPSSKATLRCYFVYQCLFKQKPEDTDPSETRLEAIADHGFLQKATNNTKQIYQEIIELAVSRTGPVIEVFDVEGTAEKRLVVAFRSRTARGIFSALSDLYHYYGVTSSRKYVEQFANGITVMSIYLRPAMNLQGDFLSMEQSIHQITKEISLLYCMPQNKLQSFVTAGELSLQEVIYGHCVWVFVQHFLNRLGSEYASLEQLLDVDNNAHAALLSKLKRRLRTETFTPDYILEIIKSYPELVRALYASFANVHLSVGPGFEKHTVDPTPAVEVMSDSSLKNFISKSVANEHEEMVFTSFRIFNNAILKTNYFTPTKVALSFRLDPSFLPKIEYPKPLYGMFLVISGESRGFHLRFKDIARGGIRIVKSRSKEAYAINARNLFDENYGLASTQQRKNKDIPEGGSKGVILLDAKSQDNAREAFEKYIDAILDLLLPAQTPGIKNPIVDLYGKEEILFMGPDENTADLVDWATEHARIRGAPWWKSFFTGKSPRLGGIPHDRYGMTTLSVREYVKGIYRKLELDPATVRKMQTGGPDGDLGSNEILLGNEKYTSIVDGSGVLADPNGLDYEELLSLAKRRVMISEYDMSKLSKDGYRVLCDDTNISLPNGEVVANGTAFRNTYHLRQTGFTDMFVPCGGRPESIDLFSVNKLIKDGRSVVPYIVEGANLFISQDAKLRLEESGCILFKDASTNKGGVTSSSMEVLAALSFDDKSFIQHMCVDAQTGEAPEFYKEYVKEVQAKICENARLEFEALWREHDQTGIARSILSDKLSVAITTLDQQLQHSDLWKDEKTRRGVLSHALPKLLLEKIGLDTIIERVPDNYVRAIFGSYLASRFVYQYGSSPGQFAFFDFMKQQTAQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPQ0</accession>
    <name>A0ABR3YPQ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein-serine/threonine kinase</fullName>
            <ecNumber evidence="10">2.7.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_005607</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the PDK/BCKDK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="10"/>
    <dbReference type="EMBL" id="JAWDJO010000201">
        <property type="protein sequence ID" value="KAL1889919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.20">
        <property type="entry name" value="Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036784">
        <property type="entry name" value="AK/P_DHK_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018955">
        <property type="entry name" value="BCDHK/PDK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039028">
        <property type="entry name" value="BCKD/PDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947:SF20">
        <property type="entry name" value="[3-METHYL-2-OXOBUTANOATE DEHYDROGENASE [LIPOAMIDE]] KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10436">
        <property type="entry name" value="BCDHK_Adom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69012">
        <property type="entry name" value="alpha-ketoacid dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Histidine kinase" evidence="11">
        <location>
            <begin position="288"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1889919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="463" mass="49814" checksum="B68B7FE42A5955C3" modified="2025-10-08" version="1">MWPRSLASARGLRFSRLHSLPIPRHHLRSLSSQVSHANEDEITQLAQQPQHPLSLADLIRHGRPPLSEEALLASANFALELLPVRLAHRIQALRSLPFIVVSNPHIKQIYQNYMHSYETLLPFARAAKVNSCSTSAKSHLSPYHSYKITSLADETRFTAVLSDLVAAHQDTIPVLARGFLECKRYIAPDHVTLFLDQHLRARIGTRLLAEQHLALHYSSHPLTTSGGSHARYANPPAHYVGVIDTALQPAECVEICASLVADMCELRYGVRPTLKIDGDHSATFAYVPMHLDYMLTELLKNAFRATVESRSDAPVVVTVAPEPAVSEEIAKPAPANQTNGDGQAGAIVRLDDKAPGVTIRISDQGGGIAPDVLPNIWSYSFTTVAEDGGSEAVGVSGAVDAGLGLGLAGVSPAGSGASSLAGLGYGLPLSRAYAEYFGGSLRVESLYGWGTDVYLHIKGIGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQ47</accession>
    <name>A0ABR3YQ47_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_005390</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000183">
        <property type="protein sequence ID" value="KAL1890466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047049800" evidence="3">
        <location>
            <begin position="19"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="246"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="227"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="307"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="365"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="434" mass="43789" checksum="90C1CFE846E02AEF" modified="2025-10-08" version="1">MKPHIVSILALGASSVSAGLISSLIKQADSSSWQPARKTSLPSEAEAGSGIGSQKLELGFIDQSPKPTAGPQVQLVGDNLFKRVDGYTMATNTCGFEDLSNLPITCLGAGAQCSNSGDYRGCCGNSQCKDLKTACVDFATNAVMGSCNSLTDSHTVCCDTDAVRSVFVCNTDSGSAKLYDYPPSLSLSGSDASATGDSDDGDSSSVQVFTTLDSSGATVTVTRDRPSASSSSSSSSDSGSNTPTGAIIGGAVGGSIVLIGALAFGVFFLRRNRQKASTAVVAQNLPPQNQQPHYPSQPLGSTAFITGAGAAGSLSPHSSSPPPPNGYGQPASPGSMTYASTTTSNVPQGYAYPPGYVPPGQGPYATAAAAPAASSHSSPVGISSEINHNAPHHTPSPPSVSGVPPPALPARAPAAVELETHHILGSNENRAELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQE8</accession>
    <name>A0ABR3YQE8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Erg26, C-3 sterol dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.170</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ERG26</name>
        <name evidence="4" type="ORF">Cpir12675_005549</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 3-beta-HSD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.170" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000195">
        <property type="protein sequence ID" value="KAL1890098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000252">
        <property type="term" value="F:3-beta-hydroxysteroid dehydrogenase [NAD(P)+]/C4-decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002225">
        <property type="entry name" value="3Beta_OHSteriod_DH/Estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050177">
        <property type="entry name" value="Lipid_A_modif_metabolic_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245">
        <property type="entry name" value="BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245:SF51">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY 42E, MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01073">
        <property type="entry name" value="3Beta_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-beta hydroxysteroid dehydrogenase/isomerase" evidence="3">
        <location>
            <begin position="15"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="372" mass="40642" checksum="E46FC9D39F844BA4" modified="2025-10-08" version="1">MASVNQPVIDLGNVMVIGGNGFLGHHIIAQLLDSQRWSTSSVTGVDLRCTRNRMEGAEYSECDITDAAKLLTVMEAVRPDVVIHTASPAAQGDSDVHKNLFKKVNVDGTACVIEACQKAGVKALVYTSSASILSDNVSDLLNVNEEWPVIRGAAQSSYYSETKAEAEALVLAANRAAPSKLLTCSIRPSGIFGEADGMTTKHTVQIYRDGRTNVQVGDNNNLFDFTYVGNVAHAHLLAARLLLATAASTTIPLDTERVDGEAFLITNDEPIYFWDFCRAIWNAAGSTKGTEHVWGLPRGVGLLMGYASEVIFSILRKPPTFNRQRIIYSTMTRYFNISKAKYRLRYSPIVSLDEGIKRAVAWSLANDHKLPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQP0</accession>
    <name>A0ABR3YQP0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Endo-1,4-beta-xylanase</fullName>
            <ecNumber evidence="4 11">3.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">XYL1</name>
        <name evidence="13" type="ORF">Cpir12675_005293</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10 11">Belongs to the glycosyl hydrolase 11 (cellulase G) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="4 11"/>
    <dbReference type="EMBL" id="JAWDJO010000177">
        <property type="protein sequence ID" value="KAL1890661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013319">
        <property type="entry name" value="GH11/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018208">
        <property type="entry name" value="GH11_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033123">
        <property type="entry name" value="GH11_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001137">
        <property type="entry name" value="Glyco_hydro_11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46828">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46828:SF2">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00457">
        <property type="entry name" value="Glyco_hydro_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00911">
        <property type="entry name" value="GLHYDRLASE11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00776">
        <property type="entry name" value="GH11_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51761">
        <property type="entry name" value="GH11_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 11 13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 11 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0858">Xylan degradation</keyword>
    <feature type="domain" description="GH11" evidence="12">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1890661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="124" mass="13515" checksum="9D81DDF9EB550BB9" modified="2025-10-08" version="1">MLGPNYTLSDLSGAYSIKWATGGNLVSGKGWKPSSARSINYSGTYAYNGNSYLAIYGWTTSPLIEYYIVENFGTYNPSSGATKVGSINADGSVYDLYTSTRTRTRTNAPSIIGTVTFKQYWAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQW9</accession>
    <name>A0ABR3YQW9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_005404</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000184">
        <property type="protein sequence ID" value="KAL1890390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18500">
        <property type="entry name" value="BACK_IBtk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051625">
        <property type="entry name" value="Signaling_Regulatory_Domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22872">
        <property type="entry name" value="BTK-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22872:SF2">
        <property type="entry name" value="INHIBITOR OF BRUTON TYROSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13540">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="318"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="371"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="5">
        <location>
            <begin position="746"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="5">
        <location>
            <begin position="893"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1114"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1314"/>
            <end position="1348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1445"/>
            <end position="1627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1114"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1134"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1218"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1316"/>
            <end position="1342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1473"/>
            <end position="1484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1485"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1505"/>
            <end position="1524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1525"/>
            <end position="1534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1581"/>
            <end position="1590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1890390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1627" mass="178224" checksum="F6027DF9EF35F688" modified="2025-10-08" version="1">MNVQLWKLFWDSDVEGFCRLLNFSAVCASGPSGGLPGLAASKDPHPGSATSPLSGKSRKGLSKSAALLLGRAELNIRDHAGLTLLLRAVSSAEPRAIHFVRALLDHPAIDIYVQDPENGWNALHRALYAGNISIARLLLEKEQHNLRNSLLGTGGRASRLIKTKDHEGNSPFDLYNSTIFKLDLPMLNSRRGRQSSYINQYPKPYFDPSSNYPGTENFVSSGNLNGNEIYMFGSNKNHSLGVGDGDDRQYPERIQLARPKNLVEYFHTKFMSSGDLITSEIGPTDQGVPQLILSRPIVIRNVALSKLHSAIITDDPFSNLYLSGVGRGGRLGLGDEHTQFRFVPVLGGLAAQKVIHVALGQNHTIAITDKGDIWTWGSNTCSQLGYTLPVSPKADEDPMSLIPRQILGTLKKETIIGAAASAIHSVAFTSTSLYCWGRNDGQIGLMDADSRSLAIQTVPRKVAASLFSSSIKMVTAAEKATTCLLQNHTVIVFTNYGYNIVRFPALDLLSNLDGPNLEALRASRSRARTTKVDYISSGGDTISALTLSGEVYVMSLNVNSLDNTPTTSSTTNPSKIKLSVTSPQRIWHARKDAATSIAVGENGSVMLSTRSGAVWRRVRRDKAKLKKSDKKRDAFKYERVPTITSAIAVRGSTYGALAVVISDTKATRSLVLVKPRALCKDISTLFPLKDFKAINIPDDLDITGILGAGLLKNGLKPFTSEVLKSMRIEEDLSKFLAATSFSSVAYDVVLSTASAPGIEIPAHSWLLAGRSSVFRELFTASLEADLSEFHDTFIFTRTSSGFKVCFKSLDIVSLLNVISMAYTDTAVPLWNYTHFAPHHATRSRQVRAEVKKLASGLNMTALEAAAQTQSGTQASMHTDFRKAISHRNFFRLGDVALQINGQEILAHRDLLCQRCPFFHGLFQGYFKGGWLSERYSRMDPRSPVRIDLSHFEPKAFAYVLEHLYSDVGVEIFDNLVTPDLDTFGGIVLAVMDIANELMIDRLIEICQSILGRFVNMRNVANILNEVSISYISSLKAASLEYISLQLEGFLENHLLDDMNDMLLSNLDHVVRYNQVLKQPYSRRRKLEYFFALYPLLIHDVAEERRARVQEMGRKFSGFQDHRPGVTGKGRRVSTDATSGTPSSSKSIHGKWRDESHHQAGSHVAPPPDPRSDDDNNLIFEMDIDTTTIPPPQVYGKLTGVPSVNCSSSKKPTKRLKSKHESLSFHDSTESRSKTPPVAPWAQVQESQPVSLITENMADAALENSYEWQSVTPSKTRKVSAFSVSPGPILSSAPPSRDQLQRISPSIIAHSATLKRPVSSTTITTPKKTTSTPLVTPTQSLPSRPLNLGDFLPDVSTPKAERKISMTIPPPPTQPAQPLTEIFDEQIEQRARDQEKVQIRPLQEIIQEEQFLQWWGDEQKRIEQQEEDERKSMRLIHELIAQENLGRTASSSGTKSKAKGKNKGKEKEIWDGVTTGSSVGNLQHASLTARPSTSTPSSSGCRTSPNPKVSLSSQQPRNNEATNRKQGSKGKGRSRRNVEHGVEGQAAASSRADGGSGGNSDGRKDGKAVTSGSGMQRRGNKGKRELGKDYGGEGGAGGAGEEAKAQGSSKQTAKREDGKPKQVPRQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRL0</accession>
    <name>A0ABR3YRL0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mitochondrial genome maintenance protein MGM101</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_005148</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
            <location evidence="1">Mitochondrion nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MGM101 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000165">
        <property type="protein sequence ID" value="KAL1890991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009446">
        <property type="entry name" value="Mgm101"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31404">
        <property type="entry name" value="MITOCHONDRIAL GENOME MAINTENANCE PROTEIN MGM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31404:SF0">
        <property type="entry name" value="MITOCHONDRIAL GENOME MAINTENANCE PROTEIN MGM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06420">
        <property type="entry name" value="Mgm101p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1135">Mitochondrion nucleoid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="242" mass="27202" checksum="9974C62FF45F181B" modified="2025-10-08" version="1">MASLRSLRALSRPFSRNTLIARIPATARPLSVSVPRFNDDTTSALAESDSDASSLAEQAVSRNTPSHIDWTTSYYGLATQPFSKEVTAILTRTVDPKLDVEMKPDGIIYMPEVRYRRVLNEAFGPGGWGLVPRGDTAVGDKIVTREYALIVHGRFISQAQGENNFFSVDQIPRAVEGCKSNALMRCCKDLGIAWQLWDPQFIRRYQTTQAEQVWVEHVVNKKKARIWIKKGDPVPYPYKKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRQ8</accession>
    <name>A0ABR3YRQ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">18S rRNA aminocarboxypropyltransferase</fullName>
            <ecNumber evidence="6">2.5.1.157</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 10" type="primary">TSR3</name>
        <name evidence="10" type="ORF">Cpir12675_005307</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1191 (Psi1191) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N(1)-methylpseudouridine(1191) in yeast 18S rRNA + S-adenosyl-L-methionine = N(1)-methyl-N(3)-[(3S)-3-amino-3-carboxypropyl]pseudouridine(1191) in yeast 18S rRNA + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:63300"/>
            <dbReference type="Rhea" id="RHEA-COMP:13852"/>
            <dbReference type="Rhea" id="RHEA-COMP:16309"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74890"/>
            <dbReference type="ChEBI" id="CHEBI:146234"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>an N(1)-methylpseudouridine in rRNA + S-adenosyl-L-methionine = N(1)-methyl-N(3)-[(3S)-3-amino-3-carboxypropyl]pseudouridine in rRNA + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:63296"/>
            <dbReference type="Rhea" id="RHEA-COMP:11634"/>
            <dbReference type="Rhea" id="RHEA-COMP:16310"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74890"/>
            <dbReference type="ChEBI" id="CHEBI:146234"/>
            <dbReference type="EC" id="2.5.1.157"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TDD superfamily. TSR3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.157" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000177">
        <property type="protein sequence ID" value="KAL1890675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01116">
        <property type="entry name" value="TSR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007209">
        <property type="entry name" value="RNaseL-inhib-like_metal-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022968">
        <property type="entry name" value="Tsr3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007177">
        <property type="entry name" value="Tsr3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20426:SF0">
        <property type="entry name" value="18S RRNA AMINOCARBOXYPROPYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20426">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN TSR3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04068">
        <property type="entry name" value="Fer4_RLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04034">
        <property type="entry name" value="Ribo_biogen_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNase L inhibitor RLI-like possible metal-binding" evidence="9">
        <location>
            <begin position="36"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="16S/18S rRNA aminocarboxypropyltransferase Tsr3 C-terminal" evidence="8">
        <location>
            <begin position="73"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="206"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="314"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="228"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="258"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="277"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="358"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="416" mass="46338" checksum="2C07F2A2F8701D47" modified="2025-10-08" version="1">MVRHKKENFRSKKSHHGPPRQRTTRDGQPSAVLPFKAACWDLGQCDPKRCSGKKLMKSGLMRELQIGQRFPGVIITPNGKKTLSPADAPMLEQFGCAVVECSWARMAEIQWSRVGGKCERLLPYLVAANTVNYGKPWRLNCAEAMAAAFAICGHLDWAETILEPFSYGQAFLDINETILKRYAACEDEASIKTVQDEWMEKLEREYHESREEDDMWTSGNTNHRAPVDSEEDESKDEESSEEANHSGDESASGIYLGKKPERKPAAEEKIKDRFDISSDEDDGDEEAAMAEIRRKVLASKTFQDAPAHKDILQIVQGESNRKGSNKASESQKFKVALDFQPDSDNGENENGNNKGSEDEGASDDDDDDDNDDFDNIIDATPMTDRIGLKKLDKARNAVKVSKASFSMKIMSAPGCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRS2</accession>
    <name>A0ABR3YRS2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_005345</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000180">
        <property type="protein sequence ID" value="KAL1890563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059065">
        <property type="entry name" value="Ig_Tag1-like_4th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059066">
        <property type="entry name" value="Ig_Tag1-like_5th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046368">
        <property type="entry name" value="Tag1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055011">
        <property type="entry name" value="Tag1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895:SF3">
        <property type="entry name" value="PRE-RRNA PROCESSING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26150">
        <property type="entry name" value="LEA-2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26153">
        <property type="entry name" value="LEA-2L_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22786">
        <property type="entry name" value="Tag1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tag1 C-terminal" evidence="2">
        <location>
            <begin position="204"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Tag1-like fourth Ig-like" evidence="3">
        <location>
            <begin position="329"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="Tag1-like fifth Ig-like" evidence="4">
        <location>
            <begin position="478"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="459"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="462"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF26153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1890563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="600" mass="64233" checksum="D3D36A40431BF16C" modified="2025-10-08" version="1">MPGDIPAIPKYTISRLEFRDVGNSAVGADIAVTAYNRHPIEASIPSLAFDVLIPDCNPLDPYLVVSRATTDQVLVSPSSNVTASAHAVIHQLPKSIMRVCPKSTSSPLDEFLHHYMNGRDTTVFIRGSRTPAKGTPAWIGALLSELMVPLPFPSHSLGDVIKEFSLTDVDFTLPDLFAEPGSPEADPKVSGTIHVVAALPKQLNFDINVTNIRASANVSYQSHKFGELHLKKWHAANSTKVHDDVTGESDLEIYSRIKSAPLTITDSDVFSEVIQEVLFGDGDIIIDADATVDVKVTTALGEVIIRDVPASGQIPVKNLPGDSLGKSLEPQISELHIIKSSSASLTLSAVVNITNPAPYSVSIPYINIHLLNKGSVLGNTTLRNVNITRGRNLNIPVSAVWAPEDAGLDARKIGVDLISGYLSSYNTTITAKLHPKSIPACPIIGQSLSNISINATVPRLSAPRDGHSPDDGSETGRGKGEFIRGATFHLFTSTATFTLVSPLQYDTITLRSVNATAFWNHTEPVGEINYDYSFDAPPGASTTPRLPVDWSVGSVGYNELLGAMGGKLKLDARANVTVAIGAYEETLWYVGRGIGAAVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSF7</accession>
    <name>A0ABR3YSF7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Pyruvate carboxylase</fullName>
            <ecNumber evidence="4 13">6.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">PYC1</name>
        <name evidence="19" type="ORF">Cpir12675_005059</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.</text>
    </comment>
    <comment type="function">
        <text evidence="2">Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>hydrogencarbonate + pyruvate + ATP = oxaloacetate + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20844"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.4.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.4.1.1" evidence="4 13"/>
    <dbReference type="EMBL" id="JAWDJO010000160">
        <property type="protein sequence ID" value="KAL1891213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004736">
        <property type="term" value="F:pyruvate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06850">
        <property type="entry name" value="biotinyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07937">
        <property type="entry name" value="DRE_TIM_PC_TC_5S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003379">
        <property type="entry name" value="Carboxylase_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055268">
        <property type="entry name" value="PCB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005930">
        <property type="entry name" value="Pyruv_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006761">
        <property type="entry name" value="PRK09282.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009554">
        <property type="entry name" value="PRK12999.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01235">
        <property type="entry name" value="pyruv_carbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43778">
        <property type="entry name" value="PYRUVATE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43778:SF2">
        <property type="entry name" value="PYRUVATE CARBOXYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02436">
        <property type="entry name" value="PYC_OADA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001594">
        <property type="entry name" value="Pyruv_carbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89000">
        <property type="entry name" value="post-HMGL domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 13 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 13" id="KW-0092">Biotin</keyword>
    <keyword evidence="5" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="6 13 19" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8 13 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="17">
        <location>
            <begin position="37"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="16">
        <location>
            <begin position="161"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="18">
        <location>
            <begin position="575"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="15">
        <location>
            <begin position="1112"/>
            <end position="1187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR001594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1891213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1189" mass="130566" checksum="848E6DACD6AE5AA7" modified="2025-10-08" version="1">MAAPVTAPTFNDVFDDSDVDEQQKTIHHIRANSSIMQVKKILVANRGEIPIRIFRTAHELSLHTIAVFSYEDRLSMHRQKADEAYVIGQRGQYTPVGAYLAQDEIIKIAVEHGAQMIHPGYGFLSENAQFARKVEKAGLAFVGPTPEVIEALGDKVSARKIAIAAKVPVVPGTEDAVETYEEIKSFTDQYGFPVIIKAAFGGGGRGMRVVRDSADLKEAFERATSEARSAFGNGTVFVERFLDKPKHIEVQLLGDNHGHIVHLFERDCSVQRRHQKVVEIAPAKDLPIETRDAILADAVKIAKSVNYRNAGTAEFLVDQQNRYYFIEINPRIQVEHTITEEITGIDIVAAQIQIAAGATLQQLGLTQDRISTRGFAIQCRITTEDPSKNFQPDTGKIEVYRSAGGNGVRLDGGNGFAGAVITPYYDSMLVKCTCLGSNYEIARRKMLRALVEFRIRGVKTNIPFLASLLTHPTFIDGNCWTTFIDDTPSLFDLVGGQNRAQKLLAYLGDVAVNGSSIMGQVGEPKLKSDIILPVLKDASGQALNVSQPCKKGWRQIIIEQGPKAFAKAVREYKGTLIMDTTWRDAHQSLLATRVRTVDLLNIAKETSHALSNLYSLECWGGATFDVAMRFLYEDPWERLRKMRKLVPNIPFQMLLRGANGVAYASLPDNAIDHFVDQAKKNGVDIFRVFDALNDVAQLEVGIKAVHKASGVVEATICYSGDMLTPGKKYNLQYYLDLVDELVKLDIHVLGIKDMAGVLKPHAAKILVGSIREKYPDMPIHVHTHDSAGTGVASMVACAQAGADAVDAATDSLSGMTSQPSINAILASLEGSDLDPGLNPAHVRALDTYWAQLRLLYSPFEAHLIGPDPEVYEHEIPGGQLTNMMFQAQTLGLGSQWAETKKAYEHANKLLGDIVKVTPTSKVVGDLAQFMVSNKLAPEDVKARASQLDFPGSVLEFLEGMMGQPYGGFPEPLRTDALRGRRKLDARPGLFLEPVDFPKTKKELSKKFGPISEADVASYIMYPKVFEDYRKFVERFGDLSVLPTKYFLSRPEIGEEFHVELEKGKVLILKLLAVGPLSENTGQREVFYEMNGEVRQVTVDDKKASVENVSRAKADASDSSQVGAPMAGVLVELRVHEGSEVKKGDPIAVLSAMKMEMVISSPHNGKVSGLVVNEGDSVDGMDLVCKITKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSP6</accession>
    <name>A0ABR3YSP6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000186">
        <property type="protein sequence ID" value="KAL1890359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="361" mass="40276" checksum="82EAA4CE65259E6A" modified="2025-10-08" version="1">MPRPRKHASKDAPNPESYQRRREQIRAAQTRHRRRATELREQLEKWRSTMQSRLIMDGSAQSDIRGQNELMWEILTESIMADGWDRVNISSLPPDQREYLLQRVNHRSQETGYYPPSPNFDASYHQPSTSSALSLESLLYSFHPQQNQGQDDQFQLLQPNSSYQMPLIHSDHELANDLLPSMGHAEMGAAYHSSGVVGAAGRLCYHTSRGMSGCPLANLGHEQLASAHRFVELLRGMCSRGASFHPSMALSSYGGPSSYQDHYGSLSSMDYRHHSMSAVTGEIDLCNEHSVDDTANTNPDTLTPVQALFFLLRRAHPNYYLVSAANLDSLGAICSRLVSCVPGSGAVVSRLDFDNAINSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUE4</accession>
    <name>A0ABR3YUE4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004739</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000141">
        <property type="protein sequence ID" value="KAL1892015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="204" mass="21168" checksum="18ACFC677CDB57AF" modified="2025-10-08" version="1">MPPQNAANQPCCQRCARLGFVCVGGRQRKIGRPSRSDVAAATSLYSANSSANTAATAPSATSVILNAAKSSKKGSSSLSSAHFWKNESSTHISGSGLNSTNTGNAPSSKSSTPEPYTVKLTAGPARSVKRSQSSAINGPARSSSVSFTMAEQSSICSDSFNSALGITDNLFQSFDEQDNRFPRTSANQLPGNVATLLDMSHADN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV59</accession>
    <name>A0ABR3YV59_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004834</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000147">
        <property type="protein sequence ID" value="KAL1891761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277">
        <property type="entry name" value="ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277:SF64">
        <property type="entry name" value="SUPERFAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01760)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="58"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="265" mass="28983" checksum="EC2A38521B16C8A9" modified="2025-10-08" version="1">MPGMPPNSSLETINDYQAGCKGILWREEKIRAADGNAGSTPPRLPDLSAVLKDLQQTSVAARFTLVALSYRGYWKSSGRPHEAGLNLDAEAAYRWILEQHGSSTPAPSLVLWVHSIGAGIATNLAASAYTRALSWTSQPALLILEAPFLSTRAMLAALYPQKWLPYKHLWPFIHNPLDSWLNVGRLAAGFGRRAPRVAIIQAENDELVPASHPEQLMKRCAEFGISVTCKSIAGAFHNEASVKPQGRRAIVGALQKMAERDQHTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YV83</accession>
    <name>A0ABR3YV83_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Small EDRK-rich factor-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004607</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000134">
        <property type="protein sequence ID" value="KAL1892284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007513">
        <property type="entry name" value="SERF-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04419">
        <property type="entry name" value="SERF-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small EDRK-rich factor-like N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="61" mass="6801" checksum="5F133293734607D4" modified="2025-10-08" version="1">MARGNQREKAREANLKKQSNQKKGSSLSGAEMQRAKETAADIMRKKQAAAEARKLEQADKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVX7</accession>
    <name>A0ABR3YVX7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_004697</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000139">
        <property type="protein sequence ID" value="KAL1892046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1892046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="121" mass="13513" checksum="921BC3D3028682D2" modified="2025-10-08" version="1">MRLPHLASLCLPFSCFRNCKPSSTDATAQPTQVAVESFETPISTALDPTSIYYLEAHGYYVWDIDVSDVGFKLYSPLYGNGIQDPVLHIDLDIDHKVNTIFDNNLKHEKPGAGPDFSWPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVY0</accession>
    <name>A0ABR3YVY0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cyclin-dependent kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_004566</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WHI5/NRM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000132">
        <property type="protein sequence ID" value="KAL1892413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039198">
        <property type="entry name" value="Srl3/Whi5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013734">
        <property type="entry name" value="TF_Nrm1/Whi5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28246">
        <property type="entry name" value="G1-SPECIFIC TRANSCRIPTIONAL REPRESSOR WHI5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28246:SF1">
        <property type="entry name" value="G1-SPECIFIC TRANSCRIPTIONAL REPRESSOR WHI5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08528">
        <property type="entry name" value="Whi5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="19"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="133"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="294"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="359"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="446"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="626"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="153"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="298"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="372"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="395"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="460"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="493"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="516"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="631"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1892413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="778" mass="81189" checksum="A5364B7C193896A1" modified="2025-10-08" version="1">MPLSDIAAIAAAAAVVSTSSSLDSPLFSPSRQQSPISKLRSQISPSHSCPPHSDSASHPLPSLCPHANDYPSSSSSALSSCSHIPSLRPGVSSPPPSILLTPPSSASPSFASSTSVLVKDAGVLAVTTDSTTTLPSTAARAPTTHKYLARPSLGSSAPTSILTPARSGPDFPSPYTCTSSRRFLPDATTATSDTIATQSGRIANAYLPNNSRSQKRTCADTHLTATTATAVGPAVVPHSHRHGLPHAHSSAPLHARVLNRVDSTSTSTSIATINPTAMNTLLSSTEPAHVTVALQHTQSPPARAPQSHSPSHSPSRSQSTSRTTLPDTTLATAAIDTQSQLLQLSHLAVLQNKMVEIASPPDPGSASLSRKRTADGVVKHDVSLPKRLGHSRNTSALSASSASGSKIGELSAELRTRLSYAMIKVSHGWQFHSIDEVESLASKAVSPSSSSSTHLRRPALSTSPGLSSTDKSMVESTTTPASFDAHSQPSPPLSKSSSTIHNSNISNDNGLAPPVSIQSRPAAQQHSRCSSRPTYTPTLLSHSQSMPPRTPASAAPTHHRRQSCTQVGSISGGEGGNSMVFSPHQNVREQDAIESLLFMSSPGNSANLKNSYAGSLASPLTQSGLRHLPFSSSAPAESTGSSQRHALPDSQPRKNLSSRKPAAAKHIVFDGNSLDDADCETNASGSLLDMSVGARGTLRRRVGLSGSYIAGPGYGPGSSHSNLHLQLPLALDTPMQTRLADEDIDRMLERVAAEDSEEDDDEIQIPQRIMVTPHVQAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW56</accession>
    <name>A0ABR3YW56_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin interaction motif protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000138">
        <property type="protein sequence ID" value="KAL1892122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055335">
        <property type="entry name" value="Ucp6/RUP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39597">
        <property type="entry name" value="UBA DOMAIN-CONTAINING PROTEIN RUP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39597:SF1">
        <property type="entry name" value="UBA DOMAIN-CONTAINING PROTEIN RUP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="405"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="949"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="415"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="958"/>
            <end position="974"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="991" mass="110018" checksum="229758520D92042E" modified="2025-10-08" version="1">MSPEPTDAAIQEVAEFTAFNDRAVITRALKANNNDTIRVVQEYFEDAEAFNRKYSWDNTVLTTDNDGNPQQGISFHIEAPTPVHPAANSDTGLDQSDAYYERLALSRPPSRTTNPSPVNRVSEWQSSVTDNNMYNYSSHPDLNLPNVTTSQEEEDLQKALRISAQESEAKIGHQEMGIATSVSPLHNSTTDTMPDTAPPPPAVSFGPARHVEYPENNWAMVSVSVNEYAKPQVYNIKPEARHRPYDTPAVLVLADKSGTISTQDRLGGIITVLHSIPLARNIFLDGSTGASYGHHHDWWKGAPILKGPSEDPLEADSLAQNEDEAELEWETQNAGVSINDELHRLVGLLEMSERSFGTINGLSDAMGGMYNLEARFFDYITGRNRQVAEPLLTVVRHVEIGTLRELEQSSNPEDANAPGEPEASAPEPTGYDSQETQVTYIEAEINSTSWPYIQSFTDIWDHVMWNDTVAYNVRPHAKSGMTCIDKQGQVMAVHINSEGHDAPFEIPRQFSVERYMTGRHDEAIGLMEMLVDQKLCLAKAKQRLRGLYELPDGTTNSSPDLTLDRFASQIRDYEAQVRYIHDRARFREFASSGFDEAKFPCGSDDAPPKLLAEEQDIVNVLNHSIKALKERYGRVAVEVESLKSHIAFHKEQLRNISTMYTDPEKPRPKPFVSQLMHLRGVVCDSGVVYLCQRQEQKLVEVDVETEAQPVDQWWRLKVVPDAEPAVQAEKVDWGRIAHGVWKDGKNPLLIYATQLALDTNPIPLPELLAKFVRFDNRLFHHELSQSTAKENDPFTNNMFTQASGHYPPSVSLTSDLDHIRSPGKRKHCFGSPDSMASNRVSIGSEVAAYGSDVDMDLQTVTGDFGSTVLDVSSGVAAGAVNRDREDDQPPSYHLIANLGDYNDPDKSDSASVHEISLSADEAAAATLDQPPTAPVVEMSQVNNGAHAMFRSNISADAQKADSKHTIKTEDKMPTEDDDADVPPLPERRPMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW98</accession>
    <name>A0ABR3YW98_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000136">
        <property type="protein sequence ID" value="KAL1892167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="817" mass="90634" checksum="0599D9455045BE6B" modified="2025-10-08" version="1">MAPGNIEDEAALAQMRLELGNIAYEVASLGKDANSSFNRTKKPSVPKTKPSAPQDESKSRIFASELGLMFQNAVFDDADSRGVKNLDINEHLILNDRILSKTLEFTTKSFQKKPTSRVTSHKPSAKLLQQPKFPKSLKAFKGPKSQNSHQSTKLSTAAKTYKPPTNLLRKLAGPVQYLCPLDKIASGGKSPTKTSSQSQSAILPHAELDPHGASRSILAPLLTPVSVQNVSVRFRRYQLAEMIDLKPNIKNSMSIELPSLTTKKSPNDFHVRYTFHELLAARIINPHVPRPSCAELVRQLRTANKVADTGKKVYVQNLPPLGAVHKNTLEVQISVPLFTEHVYDDWAGDELKSIPSYSGAFERLENSLHDCRVSDDPQFNISRHCMLFSEQISVIVEDESYTYHAVLEWVERRNGVVNSSLFLRHLSQIMYIDVMRVRRHLSILEATGLRLWFHNQANGLRARSLLSITLYFETEKMREEFASVLTRLQDAGERARDNWPSDAELTPVRRIISQEGLHANQTRILPGLPQATNTHLTEIDGDYSVDLLDDLQGFDSTSTSGFYHTPDLCDLIFDSAIPTSGIDLMDIEADQSELLTLNTQWQAISTSKNLARDPLLDEPIAPGNQSVETYLIQFEDESLGCGDTRLEPKLSLSPIMSVEVSFPVSAHCQCKARQIDNLSGRLKPTASDFQPRRLSNTTLPLMLRPTAPEFCPQQSHPDLMQASPNSEFRQFSPETLDFQPGLGISGVLQTSEVSPVQLQSMLSSYYQSQELSVSNHNVSGGSSSTSESWFSTLLDLDSPGRATNANEGVLSPGGSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWA8</accession>
    <name>A0ABR3YWA8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_004649</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000136">
        <property type="protein sequence ID" value="KAL1892181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.150">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046932974" evidence="3">
        <location>
            <begin position="18"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="144"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="203" mass="21588" checksum="218A1104A4DF07DF" modified="2025-10-08" version="1">MTATGMVLIAIVSPSWASYSVTTAAGERLHLSVGLYHSCSNNQAEPCQPFPNRTVCEGDREGFCTAWRTLGFIAYLAEIVLLVMVVCALIVAMGPPKRREVGWKILVPGLIIAASLQLWSVSMVEYLLVNASMFKVPGWKMDSAAWWFISGMLVAAASAIGLGVASVTLEGRETEGSLTLDDPLLAGERGTPEARGAAAVEGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWP2</accession>
    <name>A0ABR3YWP2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="6">2.3.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">LAT1</name>
        <name evidence="10" type="ORF">Cpir12675_004393</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + acetyl-CoA = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:17017"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="2.3.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="6">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.12" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000122">
        <property type="protein sequence ID" value="KAL1892810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004742">
        <property type="term" value="F:dihydrolipoyllysine-residue acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="entry name" value="E3-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045257">
        <property type="entry name" value="E2/Pdx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006257">
        <property type="entry name" value="LAT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01349">
        <property type="entry name" value="PDHac_trf_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151">
        <property type="entry name" value="DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151:SF90">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 6" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="8">
        <location>
            <begin position="30"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="9">
        <location>
            <begin position="170"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="126"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="126"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1892810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="449" mass="46846" checksum="9B82B5896FF4B131" modified="2025-10-08" version="1">MISNILRRHVAQPSVLRSALIRCYASFPPHSVIKMPALSPTMMAGGIGAWAKKAGDSIQPGDVLVEIETDKAQMDFEFQEDGVIAKILVDTGAKDIPVGKPIAVLVEDAGDVAAFDSFTIADAGDGAAAPAAPSTEPASAPAATPTSSVAIPETPSTPGRLQTALEREANINFAAKRLAIESGVDVSKVKGSGAGGRITVEDIKNAKASPLASTAASYVDTPLTSMRKAIASRLLESTNTNPAFYVTSSISVSKLQKLRAALNASAEGQYKLSVNDFLVKAIAVACKKVPAANSAWMGDSIREFSNVDVSVAVSTPTGLITPIVTGVEARGLESISSTVKSLAKRAREGKLKPEEYQGGTICISNLGMNTAIDQFTSIINPPQAAILAIGTTKKVAIPVENEDGTTGVEWDDQIKVTATFDHKVVDGAVGAEWIKALKKVVENPLELLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXD6</accession>
    <name>A0ABR3YXD6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the complex I NDUFA12 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000128">
        <property type="protein sequence ID" value="KAL1892571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007763">
        <property type="entry name" value="NDUFA12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12910:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12910">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B17.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05071">
        <property type="entry name" value="NDUFA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="143" mass="16600" checksum="68FE95063D9D0F8F" modified="2025-10-08" version="1">MSTITRTLSNLRKIGFKQYVIQMMTLFDGPPTTSDTKYGQLIGTDNFGNKYYENNEELPLRTRWVDYKKHDYDAGHIEPGWHAWISYAVDQPPTQDALLQTKMRKWERPESIINLTATPGAYKPYSTTVPKLSAWEPKVADRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXL9</accession>
    <name>A0ABR3YXL9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SMK killer toxin resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PKR1</name>
        <name evidence="3" type="ORF">Cpir12675_004462</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000126">
        <property type="protein sequence ID" value="KAL1892694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013945">
        <property type="entry name" value="Pkr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28251">
        <property type="entry name" value="V-TYPE ATPASE ASSEMBLY FACTOR PKR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28251:SF1">
        <property type="entry name" value="V-TYPE ATPASE ASSEMBLY FACTOR PKR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08636">
        <property type="entry name" value="Pkr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="205" mass="22622" checksum="C0A5773C4C8B8FC1" modified="2025-10-08" version="1">MASFVVELWESIFTPGPTPVLLKATNATFAALQLLLLILLLSTYSIHFVALSIISAGLWWAINWFAAELAIHQAQEDAKLKQQQQHQEHRRSSGLLDETSVNNTQPPPSDADDDTEVDEATPALVRVETPILTPPATFMPKEDKAPSPVLIGQTQNADKPTLNSWNVEPAPVTGELKQRLDASGNHSSASTEDEWERVSEYEKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYK7</accession>
    <name>A0ABR3YYK7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nucleolar Complex 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">NOC2</name>
        <name evidence="5" type="ORF">Cpir12675_004263</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000116">
        <property type="protein sequence ID" value="KAL1893117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005343">
        <property type="entry name" value="Noc2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12687">
        <property type="entry name" value="NUCLEOLAR COMPLEX 2 AND RAD4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12687:SF4">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03715">
        <property type="entry name" value="Noc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="88"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="749"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="9"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="43"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="114"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="149"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="185"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="227"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="749"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="774"/>
            <end position="784"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="784" mass="88092" checksum="3290A9BF544C20DA" modified="2025-10-08" version="1">MGKATKATKKFEKNHLKSALDNRKAIAKVKQRQQIKAKSIHRSTRDNDFYKGTEENNTSGPKLPKGAKPRDANVSAMSVDDFFQSGFEILEGTDSQKDTANLGKRKRNSAATEDSGDEEADDVDVDMTGYSDNEEDENDDDNRQMSGSDDGDEDDDEDEGMTKQAMDDLAKKDPEFYEFLRENDPEALDFDDAADLAEVDALSDGEDDEQDNKDEQSKKKRKKDAKAKKDAAEKKAQPMKVVEPVVGSELTRDMISHWKKAMQETYSLKAARQVVLAFRSAAHLNNDSAEEDPRQRFRISDSAAFNDIVIVALKQLPLVIQHHLPVKESASGRAYVQTEGNKFKVLSNLLKTYTASVMHLLSTLTDDKTLKLTISAIEPLLPYLLSFKKLLRALIKTVVRFWAQPASADTTRIASFMVLRRLMVIGDRGIRESVLKETYQGLIQGCRVTNSTTIQGINLMKNSAASLWGLDPAIGYTTAFGFVRQLAIHLRNSIVHNQNDTFRIIYNWQYTHSLDFWSCVLAEHCSSARLAEAGDKDTQLKLLVYPLVQVTLGALRLIPTATYFPLRFHLVRSLLRISRATGSYIPVAPALLEVLNSAEMRKPPKASTQKPLDFAVNYKASKAYQKTRVYQDGLGEQVAELLGEFFGLWATNIAFPELALPIVIQIKRWLKQVGKKTGGNRNAKVANGLVILVRKIEANAHLIGEKRAKIEFAPKDRTQVDTFLRDFEWENTPLGAYIAVQRKLKAEKDKMMEKARKDEEAKRKEDEKKAIEEAASEGEDEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYU4</accession>
    <name>A0ABR3YYU4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004283</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000117">
        <property type="protein sequence ID" value="KAL1893092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="251"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="554" mass="63619" checksum="36FC9CD52DA28E14" modified="2025-10-08" version="1">MSLTPVKVRGSYRRRKRPFGSINPHNETHDDPTHNTAKSVELISRAIETHAGSYIPQRHGLDLSRKSDLKVPTTSSVNRPTQPRLVAAKSRLLETLPVEILEIIFMYADSVYFPRASPLLGRALSSRSLLIAFTMYRFEYTWDFYHGLSTYRDVDFAQQDLERLDSMDANGDLEMEVITQPWLNYDIFVGALEMWHKKRNMKHWFACPKSRAEGYFDTQDPIEEESTGVHAVGTGPYTMETLDNWPIQAPSVSVPASSSSSVSSPPPATHPQVPPTCICTSPMNIEACIEKYWAMYRESATFRDILSAKFSVHERYPLCYMNSTPPFIKYSPKPETELQAFNNHTGFQVFSDIPTSNSELPQIKGIAGFRCPTSYNKVVLPKRVVWGKWFEKSAFEYSQGTDLTESNGIETYAEIAKRIKLVFLLTHHEHDDPYRTQLPESKDWETDAQAFQWMFEYLEQYVQQSLVAHIRNLGIPPIEVVALVLISARVKFWPANVCMRYYQLCNILSTQAKQKAADLQMAQDYQSQCWTARYEEIAHLVSFIRYHLGQRITE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYW4</accession>
    <name>A0ABR3YYW4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">IQ domain-containing protein IQM6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_004243</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000116">
        <property type="protein sequence ID" value="KAL1893097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044159">
        <property type="entry name" value="IQM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31250">
        <property type="entry name" value="IQ DOMAIN-CONTAINING PROTEIN IQM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31250:SF27">
        <property type="entry name" value="IQ DOMAIN-CONTAINING PROTEIN IQM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="148"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="381"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="15"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="83"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="154"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="200"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="341"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="384"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="396"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="416"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1893097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="577" mass="64731" checksum="16E229D27E3ACE0D" modified="2025-10-08" version="1">MSVLQSVTIAPPVNPSTTGLDHQRVSSMALSPDLATSHQDYLDSPKLPNSEDLANATRIQSNHQDHHPSSITHNNEAAPPDSISYNTVPVTATSPSPSENERLGQAAELIQRTYRGYRTRREINGMTINASSRFISTVHDAQFRNRMTPHARSESNATGPSSPSSPRNSDAAARWRKAGAVFQRAGNDIELDSDGDPDSSDSSADSSENDSPSVRAGQAERRRKREEAKLRRKNQAMMMNISYFLEMVDIKHRYGGNLLIYHNEWKHADTNENFFYWLDSGSGKDLDLDSCPRERLNRECVRYLSREERQYYLVKFDKDGRLRWAKNNELLDTTEEYRDSTKGIVPKDDPTPGYSASPDTTLVTGAVDGSDAVAQGILPRRDSTTSSLCHSPRSSLSEDHDEGHRRYPRPVPEAKHGKKPSKTRHIKSSHFSTTAVLNKLMRKSVRKNTWIFVADTRFRLYVGIKMSGIFQHSSFLQGSRIAAAGLIQVKDGQLTSLSPLSGHYRPPAANYKHFIKNLKLEGVDLSHLKVSKAYVILASLETYIKTKEKSKHFLERLIGQKPKEEDAELTTKAKKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYZ6</accession>
    <name>A0ABR3YYZ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pumilio y domain member 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">puf6</name>
        <name evidence="6" type="ORF">Cpir12675_004049</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000107">
        <property type="protein sequence ID" value="KAL1893619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012959">
        <property type="entry name" value="CPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040059">
        <property type="entry name" value="PUM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13389">
        <property type="entry name" value="PUMILIO HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13389:SF0">
        <property type="entry name" value="PUMILIO HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08144">
        <property type="entry name" value="CPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="PUM-HD" evidence="5">
        <location>
            <begin position="134"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="664"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="88"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="679"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="689"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1893619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="717" mass="79929" checksum="286FCB8B912DE070" modified="2025-10-08" version="1">MAVQAAGSKRKASGHGKPSSSSSPKKAKLQIRPKDKESGSRLKKTPALPPTISSQQNDSDSDEAEDFEVKDTEMVDFSDSEEGGVSLHPDRAKVVEARSQPPREKETSRESHMKQKQLVKERRAAKPLADEIARTKKLWERLRRKSHVPTEERKKLVEELFQIISGRMKTLVLKHDATRAVQTAIKYATPEQRQQIAKELKGSYATLASGRYAKFLVCKLISYSDDTIRDFIVPEFYGKIRKMIHHPEASWTLEDIYRVAATKKQRAIILREWYGVEFTLLDTNTEEPTAVLADILAKEPMKRGPAMKSLLELINSLIQKNMVGFSMLHDAMLQYFQNVQRDSPEFTEFYEMIRGNESGDLLKNMAFTKSGAHLICLLLTQGTAKDRRSILKTFKDTFILMSGDTNAHRILLTAFDVIDDTKMTSKAIFAELFGETFDKAGESLLAASQNIHARVTLLYLLEGTGLSTMFTGPKDEVRSLMEEVHELRKTTSKKDPEVRRKELVAAMSPQLLQAIADCGTQMVHDHYGCQLMSETIFAAEGDKTAALKTIANAVAGNPNEMLGGNSEDGETQGLGLISRPHPALTAHGGRLIKSLISGGKFNKATGQTIRVEPALKFANVLFPVIRPHVLEWATGPSSFVIVNMLDAPDFDDVAELRKIMSKGRPQLEKAAREGGTQKYTKEQSEELAKKKKKNNSKRPPRADPGNKGAQIILERLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ89</accession>
    <name>A0ABR3YZ89_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_003993</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000104">
        <property type="protein sequence ID" value="KAL1893693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF76">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="29"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1893693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="599" mass="68263" checksum="F5948CF0F0A777C4" modified="2025-10-08" version="1">MSSALDGSSPADASSTGHNTRVSQRASRSCTECKRRKIRCDKTVPCSQCIRAKAPAKCRIEMVELTTKYTKSRQEIEFLHRLKTALTATSLAEANDLISSRLTLLETGQEPVKSRKPVPRGSSDHFHDVLNDQQTDETFDIAKTLMRLGRGYPNPADVLDQTVPDSEFSLAVIESAPDIGIARKLVIYYLKQLSWHHPVLHHGEFLIQCESFWTTGEMITPQWACVYFAVLSASAYNLPESLCDATYTRQILRQRSEFWYQQMFNTLICTDYTLNHSMFSIQGIIISCMVAHPLGQAVRQMVLLSSSLRIAQCLGYAAQTPSRPIGSGESFDLSAKITEEVQRRIWWQILVQDYFLVPMAGSYVALLMPQLIDGLRSPTTTTREAQYRHIKFIDSKMRTLMAELPAFLRPETPFDQSWPIWIAWARSTLTISAADKNWLNRANNEQIIMIHRSFLIKSFQDPQTYDFTRRTCVSAALTILNEFHRVKNNDVVRLWIIPTFTVSAAIVIGLDISYRMKNKEAYEAKHLELLNTTIEALRMTLMDYDVTVRQGVTLLENLLTHKLNSDMSPSLWDENCTPHLDELIGYMGENQPWDTEPQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZP4</accession>
    <name>A0ABR3YZP4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000112">
        <property type="protein sequence ID" value="KAL1893381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047090371" evidence="1">
        <location>
            <begin position="29"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="147" mass="16402" checksum="73B0474999F79462" modified="2025-10-08" version="1">MRMKTTTAPLYLSLWLTAPNIQTTLALAYNIRDVLEQPGLVSPQNSIYDKESSVKGCESLLCYQVTGIDDYSESKAKVIMPVESCWVDTGNIFVWCDEDGSQTTGMLDTTSIQSPSITCTHSHVLNQTSNLNQSLDYNIHVKRYLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZT7</accession>
    <name>A0ABR3YZT7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003908</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000100">
        <property type="protein sequence ID" value="KAL1893888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045399015" evidence="2">
        <location>
            <begin position="19"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="400"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="702"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="702"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="713"/>
            <end position="731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="754" mass="78934" checksum="60C361BA568DF29A" modified="2025-10-08" version="1">MRFIAPLALLALVEISAASPLQPKASSSSHRFSVPVQTHKQAPEQTPASNVLSRPALPLLGGDGLLGDSQEPSKTKPQVIQPTGNQDSLQPTGAVSSFAPDCYTVYAPYANATRTRQPEKGNHPVYITASAPGSLITAAPSSSVICRDSQGNKVTNANTVSQYNVFYGKVTSVYTYPNGDTCTLLPQGEPAVVVSYYKEPNNTVTFTGSPEEYTAPYKNAAQPTWCNFLLTPTPIAFKTGGFIFSIDTAMANFNVLGSATTSTIYAVDHNPSVIFARSATVPNFGLPKTSVENDHLPVPTDTGIDTETDTDADTRTDTDTHTDTDADADEPPPKIAMGAAVVSSEENGVPITLAAEDPAFSNGWKPTTIIKPTPQLIEGKPQQTSNSNVWHLSLYTGMQNENQNQDPTETAAQDATKTPSTASFAITAGPDRVIINDKTYEDLGPKKTSTITYNNEVFVVEPDRIVHEGGDTMARIRPGVTGLVANISTSTVMNGLDVVVNKGTVRIGDYVYTIGPTASTEIIMGQEVVIGPTGIALEKAGKTLPYTATVPEQTEVVVAGGKMITAYGNSVVVIHQTTITYKTMDYVHTTTIDDNVLYIGRDGVVIDGTTTLGGPSADVSAIEFAIVGGVTLTQIGSSELVVLNETYTVGPNAPSNTTITAGGQTITIDAHGAVANSVTLQYPFGPSMTTTIVKTMPVPGATTSATATKTQADSGSDNTAEPSGTQNNSSAGSVLQAPALAKALAGALLVVVLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z299</accession>
    <name>A0ABR3Z299_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Small secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003712</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000092">
        <property type="protein sequence ID" value="KAL1894329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38849">
        <property type="entry name" value="SMALL SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38849:SF1">
        <property type="entry name" value="SMALL SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045441580" description="Small secreted protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="187" mass="19431" checksum="3B72225B9D9EE19C" modified="2025-10-08" version="1">MYFSKLTILSTLFVSVLAAPTCDAGVSKRADVLTVKNYADFQVSSGVAGNALQEVDDEFNAAAFRANPADVSDNDIAIMKAARVTAENAETEAGGFNEAIDAAVKDTDAGKALQNGKIKNKVMKLELQVLLADIEIGKNGDADGSVAAKRGKELTKLNKNVALDEKNAGASSTAVDFQGSSDPAASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2X0</accession>
    <name>A0ABR3Z2X0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ER membrane protein complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Cpir12675_003589</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Component of the ER membrane protein complex (EMC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EMC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000088">
        <property type="protein sequence ID" value="KAL1894602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058545">
        <property type="entry name" value="Beta-prop_EMC1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018834">
        <property type="entry name" value="DNA/RNA-bd_Est1-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026895">
        <property type="entry name" value="EMC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011678">
        <property type="entry name" value="EMC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21573">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21573:SF0">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25293">
        <property type="entry name" value="Beta-prop_EMC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07774">
        <property type="entry name" value="EMC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10373">
        <property type="entry name" value="EST1_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046147876" description="ER membrane protein complex subunit 1" evidence="12">
        <location>
            <begin position="23"/>
            <end position="1541"/>
        </location>
    </feature>
    <feature type="domain" description="EMC1 first beta-propeller" evidence="15">
        <location>
            <begin position="23"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="ER membrane protein complex subunit 1 C-terminal" evidence="13">
        <location>
            <begin position="719"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="domain" description="DNA/RNA-binding" evidence="14">
        <location>
            <begin position="1184"/>
            <end position="1366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1522"/>
            <end position="1541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="1531"/>
            <end position="1541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF10373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF25293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1894602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1541" mass="168629" checksum="3474757C32390A8C" modified="2025-10-08" version="1">MRISFLSASIWALATLPQLASSIFVDEVGNIDFHYNLIGLPKPESTFFHKPTAEANRTLLYTVSDVGVLGALLPSDGSVLWRQYLAQDGIESNGLLKPSPGEASVVSAYGSKVQTWSAFHGRNIWTREADGSVVDIAIASVAIDGRKDVFSLSKSPKSFVVSRLNSLDGSLVWSTQLDEGLNAQKLVISAEKLFVIGLSKSGVSVIPVDVSSNSISPEIVFSKSNQVPRILFVGGSLTQPIMVWSHDIEGVIYVNTLGSSSKAEIALSGSASQVNIRGSVSTGSKTYILVDSKTGKDAQVYEIGSSSVTKAYTLPGTSGMSIFSAAAVGDESYFVRATIDKVALFSWENPSAVFEWPLVVKDNKVIVDSISEVIKSSSGFNLSVAGVSSNHEWILLNDGQEAWSRVEGLSSTVAAAFANIPEDEHIAKALDQEAHTNPVAAYMHRATRHLEDLQHLPAYLQSLPDKLISAVYGKPSVAPGTRDSFGFHKILIVATSRGRVYALDTGSRGRVMWTRQVIPYTSGQTWDVIGLYADDTRHTITVMDTTGVSFTLSTVDGSVADSGAVGQPRRVQGSVLVHGNGESWILPVFEGGVLPDLVPSKVLNETVVVRGLENDVKGVKYTDDGSSHVIWSFLPPPGFTIAKVSHRDAHDPVASIGRVLGDRSVLYKYLNQNTILITLTNSEESTLINSLIDTISGQVIFSSTHKGVDVNKEFDCVLSENWMACTFFAKYVVQDGTGRVLNGVHLVMTDLYESNKTNDRGPLGMSEEASMLSPYEVPNTVGLPHAVSQAYIISTPITALAVSQTRQGITRRQILAHAPDLHSVFGLPREMFDPRRPVGRDPSKDEFEAESLPRYTANIELDPKTTLSHVREVIGITGILSIPTNMESTSLLVSYGVDLFSTRLSPSMQFDVLGRGFDRVSLVGTCLALFGGVIALKPLVVNTPLFRDPAILSAANSQTLRGSREERRRPENAQVPTFMINAEASGQGIRCGDGLDSVALSADANKLSASIDERRMATLHSRLTNLIEESYATISIIEARCAGTSAPQPESSASFANGRWRTLHKLHSNLISAYHTFFAITQDRYATTAMRRLPLAYEMPRRLWEIGMYSLLEPMRLGLPDSREHMHHFWAKSYGMMCLMLETMGAFRLQWTEVLGALSRYRVFIEEGNGRDAQEGRMSWVAVARSWYCLALDLAPGMGRLYASMGLLSLTSGLERLFYYLKALCVQEPHADTQGRLVGLFDAVAATTVEVQGTDLPPVETAFVCMHGILYRLSLGECQPADVELWKIRVEEKQREFLAELKQDIVRNPIRWARTGAFVALINIFALYEYRPQQGPRSSGQSTNSLVFSIAVRIFILTLQTILDSTVEPCCFSFLHSTFAYLAYSVDIVKCSFALYCLPWPLVISYANALQVTINSAYANEMTQLGHLRSWGTLAEDYSIRGFEFAECYFQTPDWVAGSPDESERLLEHPQAPLLRTVRIVSLLRVMADRTQGRFMTMNATNLRWELSVPLAIAVAAQMSRGSYGRDPRAGGTGVQANSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2Y6</accession>
    <name>A0ABR3Z2Y6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase</fullName>
            <ecNumber evidence="3 12">2.4.1.131</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">ALG11</name>
        <name evidence="16" type="ORF">Cpir12675_003415</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes, on the cytoplasmic face of the endoplasmic reticulum, the addition of the fourth and fifth mannose residues to the dolichol-linked oligosaccharide chain, to produce Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>an alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP-alpha-D-mannose = an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:29523"/>
            <dbReference type="Rhea" id="RHEA-COMP:19515"/>
            <dbReference type="Rhea" id="RHEA-COMP:19516"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:132511"/>
            <dbReference type="ChEBI" id="CHEBI:132515"/>
            <dbReference type="EC" id="2.4.1.131"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11 12">
            <dbReference type="Rhea" id="RHEA:29524"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.131" evidence="3 12"/>
    <dbReference type="EMBL" id="JAWDJO010000080">
        <property type="protein sequence ID" value="KAL1895000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004377">
        <property type="term" value="F:GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03806">
        <property type="entry name" value="GT4_ALG11-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038013">
        <property type="entry name" value="ALG11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031814">
        <property type="entry name" value="ALG11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45919">
        <property type="entry name" value="GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45919:SF1">
        <property type="entry name" value="GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15924">
        <property type="entry name" value="ALG11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 12 16" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="31"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="ALG11 mannosyltransferase N-terminal" evidence="15">
        <location>
            <begin position="105"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="14">
        <location>
            <begin position="353"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF15924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1895000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="548" mass="60259" checksum="88800A530899203B" modified="2025-10-08" version="1">MESSNPGVRSASSHTTCNASSSSWFRQDTLLYLALALIAIGAYNMFLVLVVLRAIGASFGWYLWTKTAGRRASILSSVSEPEVLFEGSNVGGSKNTTASSLGRGKIIGFFHPFCNAGGGGERVLWAAIRATQTHWPKARIVVYTGDLNVSKDNILSRIKHQFNIDIHSPTITFLYLSTRHWVLPSTWPRFTLIGQSIGSLILAWDAFQLVVPDAFIDTMGYAFALGLCKFLFRNVPTCAYVHYPTISTDMLTSLDPNSPTGNLGVNAGQGVGWKGKAKKIYWQLFALLYSRAGASVDIVMTNSSWTQGHINKLWTPYRTGSGGKTTAPITVVYPPVAVEEMASKIEVSAASESQREKAILCIAQFRPEKNHQILVESFAKFVATRTPASEGSRLVLIGSVRDDADSKLVYELRLLVNELGVKDRVDFVLDASWPKVLQWLSKASVGVNGMWNEHFGIGVVEYEAAGLIPVVHNSGGPKLDIVTEVDGKPVGFHATTAEEFAQCYEKALSLEDPLAVRLRARQSAQRFTEHVFATRWIEEMERLMALSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3V2</accession>
    <name>A0ABR3Z3V2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Pre-mRNA-splicing factor 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PRP8</name>
        <name evidence="9" type="ORF">Cpir12675_003331</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000076">
        <property type="protein sequence ID" value="KAL1895314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08056">
        <property type="entry name" value="MPN_PRP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13838">
        <property type="entry name" value="RNase_H_like_Prp8_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.40">
        <property type="entry name" value="Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012591">
        <property type="entry name" value="PRO8NT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012592">
        <property type="entry name" value="PROCN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012984">
        <property type="entry name" value="PROCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027652">
        <property type="entry name" value="PRP8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021983">
        <property type="entry name" value="PRP8_domainIV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043173">
        <property type="entry name" value="Prp8_domainIV_fingers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043172">
        <property type="entry name" value="Prp8_domainIV_palm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019581">
        <property type="entry name" value="Prp8_U5-snRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042516">
        <property type="entry name" value="Prp8_U5-snRNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019580">
        <property type="entry name" value="Prp8_U6-snRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019582">
        <property type="entry name" value="RRM_spliceosomal_PrP8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11140">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR PRP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11140:SF0">
        <property type="entry name" value="PRE-MRNA-PROCESSING-SPLICING FACTOR 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08082">
        <property type="entry name" value="PRO8NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08083">
        <property type="entry name" value="PROCN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08084">
        <property type="entry name" value="PROCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12134">
        <property type="entry name" value="PRP8_domainIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10598">
        <property type="entry name" value="RRM_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10597">
        <property type="entry name" value="U5_2-snRNA_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10596">
        <property type="entry name" value="U6-snRNA_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="JAB1/MPN/MOV34 metalloenzyme" evidence="8">
        <location>
            <begin position="2134"/>
            <end position="2270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1895314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="2372" mass="274938" checksum="EF6DB01CE1FB84E7" modified="2025-10-08" version="1">MSGLPPPPPPGWAAPPPPPSSFLPPPPSAPAPPPPPGYCSANDLQLVKFAPKKKEWLRDRRLRFGEKRKGGFVETQKADMPPEHLRKIVRDIGDVSQKKYTNDKRSYLGALKFMPHAVMKLLENMPMPWESTREVKVLYHVNGCLTLVNEIPRVVEPVFFAQWAMMWVYMRKEKQDRRLFKRMRFPPFDDEEPPLSWSENIEDVEPLEPIQFELDEDDDEAVYEWFYDHRPLLDTPHVSGPSYKTWNLSLRQMATLFRLSRPLISDVVDKNYFYLFDLPSFFTAKALNVAFPGGAKFEPLYKDIDPNDEDFGEFNAIDRIIFRTPTRTESRVAYPYLYNSLPRSVSLSWYSHPQVVYSKPESPDLPAFHFDRRLHPISSRNVKPMNIELSHEDEIFGVGNNEESEDFLFELPPDLEPFLADEELENEDTADAIQLWWAPFPFDRRSGRMVRAQDVPLVKQFYLEHPVPNDKNRIPIKVSVSYQKLLKTYILNELHEKPAKSLNKQSLLKSLKQTKFFQQTTIDWVEAGLQVCRQGFNMLNLLIHRKNLTYLHLDYNFNLKPVKTLTTKERKKSRFGNAFHLMREILRLTKLIVDAQVQYRLGNIDAFQLADGILYAFNHVGQLTGMYRYKYKLMHQIRTCKDLKHLIYYRFNAGPVGKGPGCGFWAPAWRVWLFFMRGIIPLLERWLGNLLSRQFEGRHSKGVAKTVTKQRVESHFDLELRASVMADLMDMMPEGIRQNKVQTVLQHLSEAWRCWKSNIPWKVPGLPAPIENIILRYVKAKADWWISVAHYNRERIRRGATVDKTVAKKNVGRLTRLWLKSEQERQHNHMKDGPYVSSEEAVAIYTTTVHWLESRKFSPIPFPSVSYKHDTKILILALERLREAYSVKGRLNQSQREELALIEQAYDSPGTTLERIKRFMLTQRAFKEVSIDMNDNYSTINPVYDIEPMEKITDAYLDQYLWYQADQRHLFPAWIKPSDSEVPPLLTYKWTQAINNLDGIWDAENGECNVIIETELSKVYDKMELTLLNSLLRLIMDHNLADYITAKNNIQLTYKDMNHVNSYGMIRGLQFSGFVFQYYGLVLDLLLLGPQRASEIDGPPQSPNGFLQFRDKETETRHPIRLYTRYIDKIWILLRFTAEESRDLIQRYLTEQPDPNFENVIGFKSKKCWPRDCRMRLMRHDVNLGRATFWDLKNRLPRSLTTIEWDDSYVSVYSRDNPNLLFSMCGFEVRILPKCRNQNEEFSVKDSVWSLVDNTTKERTAHAFLQVTEGDIAKFNNRIRQILMSSGSTTFTKIANKWNTALIALFTYYREAAVSTIPLLDTIVKCETKIQTRVKIGLNSKMPSRFPPAVFYTPKELGGLGMISGSHILIPASDKRWSKQTDTGVTHYRAGMTHDEETLIPNIFRYIIPWEAEFIDSQRVWTEYSQKRLEASQQNRRLTLEDLEDSWDRGLPRINTLFQKDRSTLSFDKGYRVRSEFKIYQLMRSNPFWWTSQRHDGKLWNLNAYRTDVIQALGGVETILEHTLFKATGFPSWEGLFWERASGFETSMKFKKLTNAQRSGLNQIPNRRFTLWWSPTINRANVYVGFQVQLDLTGIFLHGKIPTLKISLIQIFRAHLWQKIHESVVMDLCQVFDQELESLGIEMVQKETIHPRKSYKMNSSCADILLFASHKWNVTRPSLLYDTKDVVEPISTNKFWVDVQLRYGDYDSHDIERYTRAKYLDYTTDSGLYPSATGLMIGIDLAYNLYSAYGMYFPGLKVLVQQAMAKIMKANPALYVLRERIRKGLQLYASESNQEFLNSQNYSELFSNQTQLFIDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSVWAGQKRLGQLAKWKTAEEVAALIRSLPQEEQPRQLIVTRKGLLDPLEVHLLDFPNISIRASELQLPFQAAMKVEKLGDMILRATEPQMVLFNLYDDWLKSISSYTAFSRLVLILRALHVNQDKTKLILRPDKSVITLDHQIWPSLSDEDWIKVETQLRDLILHDYSKKNNVNVASLTSSEVRDIILGMEISAPSMQRQQAAEIEKQQQEQAQLTAVTTKTQNVHGEEIVVTTTSQFETQTFTSKTEWRTRAIATSNLHTRSNNIYVSSVDSDSDDSITYVMPNNILKRFITIADLRVQIAGYLYGISAPGTNDQIKEIRCIVMVPQVGQLRSVNLPQQLPQSDQIDGMELLGIIHTVAGNELPYMSSVDVTQAAKLTESHEAWNRESTITVAVSFTPGSVSLSAWGLTPQGYKWGLDNKDLGSDQPQGFTTTMGDKRKLLLSPRFKGFFLVPELDRWNYSFLGTVFDGMAKKPVRVKLDTPRPFYSEDHRPTHFHDFSQLEDVGVDRDDNFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z446</accession>
    <name>A0ABR3Z446_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000081">
        <property type="protein sequence ID" value="KAL1894982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="657" mass="72910" checksum="1707E0CEEC2502F2" modified="2025-10-08" version="1">MTSTYFHHAVEKPSAEILAQYLAAIGDKKKVFFEDILLGVEAQVSPGSASSDQNYETISRSDTEDTSEMSSLNPLLRATRPDRVVLTQDTPLSNCTAPKSESEPYRLVIGQHKPPHALRTADPQSTPVLPEDCLIRMAIASRTSMARKDEESKDFRRLPSSSATESLLHACPEMAENQVFFASDLAEAYHYMITSGLEYGYLVTGHAIAFLRIPLTEPTTLLYYTSTFHVDSPNNSPLSSSFSRHLDSVVPPSALRGVDRQGGDALAELAVSQLCSLFILASRSPKRPFSWVSGALRNLSRFPELPDDGQRRDVLPCPVQNCGEHRRPTGHALPPHGEDSSHGGATVGAAKEKADLPYCTQKCLLGLMRGLPLDIKCPNYLLHKDTPLAEAPHPSNAPGTSYESRKAEEQWRQRHPITGARVSELVREQIGVDPEASCALLYSQGLYGAVGCLLRLSVKGYGYTFVAKGVESMNSGHLQHETYVYKYLHRHQGILIPVHLGLVELRSPYPFMAKFTSLSHFMLMSYAGKSLNYGSSMDALSRKLGRDLVQEIEDTYDELSDWGLDDQDNVCNAAWCEETQRIMKIDFDHCILHADVYMAKSRAEATEYRLGSSAVRKRAMIMMNDDNDNDLEIQRGMRRPRSGLGPALKRVKYARGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4R7</accession>
    <name>A0ABR3Z4R7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Nucleoporin NUP82</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_003186</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000071">
        <property type="protein sequence ID" value="KAL1895548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037700">
        <property type="entry name" value="NUP88/NUP82"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13257:SF0">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13257">
        <property type="entry name" value="NUCLEOPORIN NUP84-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="6" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="84"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="859"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="818"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="860"/>
            <end position="875"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1895548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="922" mass="101341" checksum="4B01AF688AE9CEC2" modified="2025-10-08" version="1">MPKVKAYTPSYLATGAPGNALFAATNESCSPYASKKKQNAKSPQAGPRRTIARRGTELFVARGREIRWGDLAYLKEMQEDRRAKSSRRSVLIKREDDDGATAASTSPDEFGSGYRTIKAPVADDIRQLIISPNNNYVAVVTTHTCHIMVIPDSSHLTSGDSGPIKPKIWTLGPVTHVSTKSALASVLWHPLGVDGGCVVTVSEDAIVRVWELSMTDRWSFDQPTLDIDLKKLADGVALDQIFSASVSATNTGFSPDSFEMEVAAACFSSRQSGGWSPFTLWIAMREGDVYALCPLLPQKWSAPPALIPSLSVSIVEKLGTIEDDVETSEYERLLAQQQLAWMAEIDSQEPQLVEASPGDAIIEVFTRPSKPGSCPRLQGPFDICADLKDQDDIDCEYTDIMVIGPKIDSEELMYGEDVDLVTEGTEHEGLSLSVVCLLSTGGQVKVCIDIDGVEAQWLPSKHKTRLSHLADQVPEPSLLLYQAMDSMNTTESNPESWPVFSTDVMSKYAFYVTHNVGITYFSLASWVFRLESELQEPGAGSEFRIGLLVTGHNSTRERLYVETSSHSPNYLSACVAIDDPDIGYGIISSTPYEPVVLLFDLPEEQLAVIRQESPDTTDPTEHLPEPSPQPLFTYEPRPAYTPSQAFGQLSLLPMFLERLKTSNQRMTLGQGVRLSPMTLQVLTNVHKILSDETHSLGLAASDLFLKCDRMHAEMRAQLAKAAEIKARIDKIVGGDEPCDRIRVDSRLAQAQSRQIHLAERLEALRNANHVSRRELSTKERAFADEVQSLKARVLGSGEELSVAPCRSNANVTEPWQRVNTVNQLADELLRDARELVAEQEQRNARVIAAVSSTANIGTAVSSSPVTSTPTGVESPARLGTPDLRIPPELRKTRLQQVKTMLARETALIEAVTARLERLQTEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5G4</accession>
    <name>A0ABR3Z5G4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003146</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000070">
        <property type="protein sequence ID" value="KAL1895565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045464">
        <property type="entry name" value="Hrt3/FBXO9_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12874:SF9">
        <property type="entry name" value="F-BOX ONLY PROTEIN 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12874">
        <property type="entry name" value="F-BOX ONLY PROTEIN 48-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19270">
        <property type="entry name" value="FBO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="212"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="156"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="35"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1895565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="529" mass="59464" checksum="721B56DA81BB2AA3" modified="2025-10-08" version="1">MASSKSHSLQPLSSELEDFRSQWLHDLQANKDDSTGVTKQTSGSSVTASTPLDIKQDDEEFDIEVAQNPSVVLEPALIEDVESSSDEEDHAGPAFGASLFEYESQKKGKPELVSALDHFEEAIKKEAHGNLGDSLSLYRKAFRMDSAVDKTYRQKHFPSKPKTEGQKLASQIQKDSDETPTLPLSMDELLISFSSLQIEPAPPIIEGTLPPPCPIASIPYEILYAIIGHVAAHDIGDFARLAQVCKRMAFIVASEERIWRAACLSFRFGYPSMHYAFHRTVRGTLATELASHSAFAQQQHEAHVDARRLARTEKVCAALLSQKPYSGSWHRLFRWRPRLRFNGCYISRVNYLRDGQTGPDQKTVWTPVHVVTYFRYLRFLRDGTVLSLLTTEEPAVVVPVLASVQGREEADVPGAHRLLAYLLRGRWRMADPLAKEPLRRFPDGGDEEASPFEVDGDIVVETEGIVPKYTYLMQLALRSSGKVAVNNKINWTGFWSYNGDTERWSEFPLKNEKPFIFSRVKAFGFGELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5R1</accession>
    <name>A0ABR3Z5R1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Proteinase B</fullName>
            <ecNumber evidence="11">3.4.21.48</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PRB1</name>
        <name evidence="11" type="ORF">Cpir12675_003015</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.48" evidence="11"/>
    <dbReference type="EMBL" id="JAWDJO010000065">
        <property type="protein sequence ID" value="KAL1895975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6 7" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046224454" evidence="8">
        <location>
            <begin position="16"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="10">
        <location>
            <begin position="44"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="9">
        <location>
            <begin position="184"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1895975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="531" mass="56697" checksum="687DDE7DB23061C3" modified="2025-10-08" version="1">MKGGLVFLLAASASAASSSFSTETIHSDAAPILASVNAEAIPNSYIIKFKKHVDEKDASSHHSWVQSLHDESEEKRLELRRRDLDVGILSGLKHTFNIGKDFRGYAGQFDDELVEQLRRHPDVEYIERDTIVHTMRTLPSTPEVEESCSPETEKNSPWGLARISHRDSLSFGTFNKYLYADNGGEGVDVYVIDTGCNTEHVDFEGRASWGKTIPAGDDDIDGNGHGTHCSGTIAGKKYGVAKKSSIYAVKVLRSNGSGTMSDVVKGVEWAANAHIQATKDAKAGKRKGFKGSAANMSLGGGKTVALDQVVNAAVDVGVHFAVAAGNDNADACNYSPAAAQKAVTVGASALDDSRAYFSNWGKCTDIFAPGLSIQSTWIGSKHAVNTISGTSMASPHIAGLLAYYLSLQPAADSEYSVLPLTPAELKANIINIATEDALSGLPKGTPNVLAWNGGGCSNYSSIIKQGGYKVKADPNSRLDLEELEDAINGELNVMSGKVLKGAESVISKAQKFSDRVHEIVDEEIREFVESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6T1</accession>
    <name>A0ABR3Z6T1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Atos-like conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003019</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000065">
        <property type="protein sequence ID" value="KAL1895979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033473">
        <property type="entry name" value="Atos-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025261">
        <property type="entry name" value="Atos-like_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051506">
        <property type="entry name" value="ATOS_Transcription_Regulators"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13199">
        <property type="entry name" value="GH03947P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13199:SF11">
        <property type="entry name" value="PROTEIN ATOSSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13889">
        <property type="entry name" value="Chromosome_seg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13915">
        <property type="entry name" value="DUF4210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01177">
        <property type="entry name" value="DUF4210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Atos-like conserved" evidence="2">
        <location>
            <begin position="267"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="508"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="630"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="523"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="638"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="649" mass="69668" checksum="A3521B857DDC15DC" modified="2025-10-08" version="1">MPSYMQTQYSPLEQLPKTTPTHSSSPSPSLTPTLHNLSDAISGEAPASSLNFAAAPAAVGLAIQRPHSALHTGNFSAEAIHPYPNPQPSAPIPCSWNGVAGSSQPIGLEPLQTNAFPARRRSSVCRNSLVFMPPTSPLAQSASPDDIVDRLPLSVGQIALSGSTASKSGRSLELRRSSFSHTMSSSRSVHIQWFRSPADKKGSGLSLSASVGASSVFIDPVASLRQTPLSISPPFPHQHHNHSINHSLSHCHHPSSRRLSSTDHAPLVGSYEESLLRGRMSTVPSRPLTFNAQIGVLGRGNCKPSLRCPAHVTLPFHAVFYDYPSKARDSRGTGVGSGGIADDGGPSPYVGTVDLENSLLAYGAQSQQKTGEQRRKKTKAHSEDTATRAPPGGSYRIPEVGQLQIIIKNPHKTAIKLFLVPYDLTGMQPGTKTFVRQRCYSLGPSASPIASGGSGQASGPLQAHNRPVLRYLVHANICCPAKGRFYLHKDLRLVFANRVPDSHEKLRTEMTSPEPRFSAYRPTRSSELGTARSTKARHGRTRSYGDVFSQTLARLGDGGGDHGVDMRSPQDAHLGSKTYADAVESPSETSPSILPEASKTWEYQKLSPDKVSSRVGSLAPQSLLSWGLWSMNSVQDEEDKKEKVDNAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7J8</accession>
    <name>A0ABR3Z7J8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Solute carrier family 40 member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_002731</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in iron transport and iron homeostasis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000056">
        <property type="protein sequence ID" value="KAL1896635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009716">
        <property type="entry name" value="Ferroportin-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11660">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 40 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11660:SF57">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 40 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06963">
        <property type="entry name" value="FPN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1896635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="511" mass="55200" checksum="C0A5742B124B95E1" modified="2025-10-08" version="1">MSLEQAEAGAGPLVLGLTSNEASFMHTDSCLSNGVLPSPTPLPSSSSPSNSTTRLFNASVFLPQPSLATLTPRLYISHFLSTWNSRLFEFGAVLFLAAVYPGTLLPLSLYALARGIAATLLSPSLGLVIDTYDRFRVVRASIIIQRLSVAVSCVGFYILYTIRSPPSELLAVHGLLRTRSNPFLHHPIQHAIFGAVTFLGCAEKLAATLNTVAVERDWVVALTHNDAQARTQLNRRMRQIDLFCKLLGPLVIALIDSVDTPAAIGVSCGMSLVSAGPEYVFIEQIYNCVPALQRLGPNSTEGEKTPDSASWNLRGARNAAWVALVQPLRTLPEYVRHPAFQPSFALALLYLTVLSLSGQMVAFLRATGFSSAQIGAARVVSSLFELSATVIAPRLAEAIGPVRAGIWALSWQTVWLGISLSCFFWRIGDQSSEILSGGVVGLVGGVMVSRVGLWGYDFAAQTIIQNEVDEFQRGSFSAMEASIQNLFELLAFATTAIFHRPEQFRIPTLTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7R1</accession>
    <name>A0ABR3Z7R1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002717</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000055">
        <property type="protein sequence ID" value="KAL1896695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="192"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="347" mass="39083" checksum="C6C5C9C1B3A7B929" modified="2025-10-08" version="1">MSGKLQYSAVEPPMTSSSRSAYTATVPPSSSSAFLRPDAPRSDFLAPTTSRGHRRSSSAVDGTVSLGPPSGSRHRMSFSDVRDEQNPRELRDFRDREKDRNRSSRSTHRGTSSDSRGHAPPGIMFSHEASDPSLDKSRRNSIYDKDQRGSGSRSHHGHSHSYSGSASRHDSPEPYSSDEERGGSGKTKKRVLAALAGVVAVGLGVNAIDKKINESNKRRDEIQEEQDRKYERDREWERRSGRDHDHDSRSHYSSHSQHHPSSHSQAGVGVIVPASSRHPDRSDQGRDGDRGRYREKDAVECNRSRARDYRMEVSRDRANYHEARASDDRLYRLGDEEYYDPYSGRNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7S9</accession>
    <name>A0ABR3Z7S9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">JAB1/MPN/MOV34 metalloenzyme domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_002686</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M67A family. CSN6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000055">
        <property type="protein sequence ID" value="KAL1896664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540:SF8">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JAB1/MPN/MOV34 metalloenzyme" evidence="3">
        <location>
            <begin position="15"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="395"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="410"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="425"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="435" mass="46724" checksum="3C65BC13C5AEA03B" modified="2025-10-08" version="1">MAVPLISSQKSTDLQLSIHPIVLLSISDHIARHTLRPMAQPPLPLVGLLMGFQEGCKVSINRTFDIAVKSSLENVPGECHIDNEVLSFCDQLQSHTHVVGYYTILPRSGPDHGVLAMHEKLSRKFPDRDLLLLAFHPDEDIGRTNILPITIYESRLLTSAGVSVNARDNDVVLSGTDEVAPAITAAAPMQRQFYEIPQYTVVTDDAEMIGMDFVAAGGGNAKAVTKADNDDVKSNTQNTLVEAKDTANKDKDMEKEKGKGKEADIGKDAALQLTRDEEDVIAALKTKANAIRMLQARVKLLASYLSSLPESFVSTGIVPTDIPSANSTPDHNILRQIQAAVVRLGLIVPSDVDAFSAELANEETSIATVALINDMVQAAYDSHLANRDFVAADTPSASSMGRGKKGLAVQGNTSLSTGVSRGRGAGRDLAVHMRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8H5</accession>
    <name>A0ABR3Z8H5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">4-coumarate--CoA ligase-like 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_002605</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000052">
        <property type="protein sequence ID" value="KAL1896956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF295">
        <property type="entry name" value="ACETYL-COA SYNTHETASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="2">
        <location>
            <begin position="45"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="3">
        <location>
            <begin position="521"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="632" mass="68866" checksum="4291A818B96A5059" modified="2025-10-08" version="1">MSLAISKSPCVQIPKRSISDWAFGRPFCQDNSFLPPTMHIPPFQGERPIFVDNKTERTLCFDTLKKDALKVAASLEALGLHFNDTIKLPSTPTCSSPQVAPLVLIQLPNCQPFVPLTLGVFAAGLTATLVSPALTTDELSWVLQNARPRVIVTARACWPAMERALDKQDDRAYFGSIKVFTVDTDGDVYPLVSSGAVAESPVGHDWKHLLCPPGPLKFSTSLLPAEAWASRTALILWSSGTSGRSKGVLLSHHSINSSLASLWIHSDQYSGRQEKWLGFVPFYHIFGFVTIFMLSICTGSAVYLMPSFNLDAMLAAIPKHKITYLHMAPPIAVMLAKSMAVEPYAKKNDRGENSFTSISAGFTGGAPLGHEIILQVYKRLGFRIRMGYGMSEAGSIASQHGLTEKDMHFQAGTSGQPLAGVELMISSDQPDFQGGQTKPALINTPGEILIRSGALMSSYLPLGGLSPGAKVDMTPTLEALTPDGWLRTGDVGTLDAGGHLRITDRIKELIKVQAYQVAPAELEALLSSHSAVEDTGVVGIYDQSEATEWPRAFVVVRDRAQTEHQLRALAEELKQLVEAKTVKYKWLIGGIVFVEQIPKSPSGKILRRVLRDEQVSGLEVSLYARKHRPSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9C6</accession>
    <name>A0ABR3Z9C6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Protein PET100 mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_002461</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the PET100 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000048">
        <property type="protein sequence ID" value="KAL1897204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018625">
        <property type="entry name" value="Pet100"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33968">
        <property type="entry name" value="PROTEIN PET100 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33968:SF1">
        <property type="entry name" value="PROTEIN PET100 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09803">
        <property type="entry name" value="Pet100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1897204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="90" mass="10356" checksum="2F436659917807B1" modified="2025-10-08" version="1">MGGFNLEVFKFGMYVMFPIGTMYYFGTNLDQRFAVEGFWPKPEETNKVPHTREEIKAEYERIVARQRLLKEKEAMRRAAAGQGPSASESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9E3</accession>
    <name>A0ABR3Z9E3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">HRR25</name>
        <name evidence="7" type="ORF">Cpir12675_002397</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000046">
        <property type="protein sequence ID" value="KAL1897293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14125">
        <property type="entry name" value="STKc_CK1_delta_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050235">
        <property type="entry name" value="CK1_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11909">
        <property type="entry name" value="CASEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="14"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1897293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="328" mass="37759" checksum="DB1B2413A7903D4F" modified="2025-10-08" version="1">MSSTAMDLRVGSKYRIGRKIGSGSFGDIYLGTNIISGEEIAIKLESVKAKHPQLEYEARVYKSLAGGVGIPFVRWFGTECDYNAMVMDLLGPSLEDLFNFCNRKFSLKTVLLLADQLISRIEYIHAKSFIHRDIKPDNFLMGIGKRGNQVNVIDFGLAKKYRDPKTHFHIPYRENKNLTGTARYASINTHLGVEQSRRDDMESLGYVMLYFCRGSLPWQGLKAATKKQKYDRIMEKKMTTSTEVLCRGFPNEFAIYLNYTRSLRFDDKPDYSYLRKIFRDLFVREGFQYDYVFDWTVYKYQKNAAAIAQQNGEDLDKSRIAGGMALNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA03</accession>
    <name>A0ABR3ZA03_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LYC1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002616</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000053">
        <property type="protein sequence ID" value="KAL1896895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055100">
        <property type="entry name" value="GNAT_LYC1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053013">
        <property type="entry name" value="LAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34815">
        <property type="entry name" value="LYSINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34815:SF4">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22998">
        <property type="entry name" value="GNAT_LYC1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LYC1 C-terminal" evidence="2">
        <location>
            <begin position="202"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1896895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="398" mass="44154" checksum="D2744D5692F38287" modified="2025-10-08" version="1">MTGDSNATDFSGSKTMTTDSAELPAASSPDVIISHPTPDECSHVYTLTSADWGAALPTRADYIRREKFLTHLPLSQRGSARQWILTTTSAPGTRPILSSCDTLRRRGLVAMDGTVDEVEVQAIGAVYTDPAFRGRRYAQRLMQLLQQEMETPASDTGHVTPGLSVLFSDIGKTFYAKLGWNVHESRHVEIRPSITGLPGAAEGEAQKAQPLRMHDLAELCVLDEAVLRKSMAKSTETAIALIPDYDTMLWHHLREDFMTTTLFEKSPAVRGAISGPVGGRVWAVWVRSYYSGASDPKDNTMHILRMGFEDQKNMSNNELAGRLTGILDIAVKEAHEWVTSSVHMWNPSEQVIRALEKTGIEFSMVDREETSIPSVMMHGKFHGKTASKWIINEKFGWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA64</accession>
    <name>A0ABR3ZA64_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Coatomer subunit beta'</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">SEC27</name>
        <name evidence="17" type="ORF">Cpir12675_002329</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Cytoplasmic vesicle</location>
            <location evidence="1 12">COPI-coated vesicle membrane</location>
            <topology evidence="1 12">Peripheral membrane protein</topology>
            <orientation evidence="1 12">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Golgi apparatus membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="12">The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the WD repeat COPB2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000044">
        <property type="protein sequence ID" value="KAL1897541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22947">
        <property type="entry name" value="Coatomer_WDAD_beta-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006692">
        <property type="entry name" value="Beta-prop_COPA/B_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050844">
        <property type="entry name" value="Coatomer_complex_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016453">
        <property type="entry name" value="COPB2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011045">
        <property type="entry name" value="N2O_reductase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056176">
        <property type="entry name" value="TPR_COPA_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876">
        <property type="entry name" value="COATOMER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876:SF2">
        <property type="entry name" value="COATOMER SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04053">
        <property type="entry name" value="B-prop_COPA_B_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23953">
        <property type="entry name" value="TPR_COPA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005567">
        <property type="entry name" value="Coatomer_beta'_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50974">
        <property type="entry name" value="Nitrous oxide reductase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 12" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="7 12" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <keyword evidence="5 13" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="13">
        <location>
            <begin position="93"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="13">
        <location>
            <begin position="136"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="13">
        <location>
            <begin position="195"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="13">
        <location>
            <begin position="224"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B second beta-propeller" evidence="15">
        <location>
            <begin position="318"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B TPR" evidence="16">
        <location>
            <begin position="594"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="810"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="819"/>
            <end position="849"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR005567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF23953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1897541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="849" mass="94652" checksum="F3D20F73BAC19B3F" modified="2025-10-08" version="1">MRLDVKRQLFARSDRVKGVDFHPTEPWILCTLYSGHVSIWSYETQQVVKTFELTDVPVRCGRFVARKNWIVCGSDDFQIRVYNYNTSEKVAQFEAHPDYLRSIAVHPTQPFILTSSDDMTIKLWDWEKGWKCVQVFEGHAHYVMSIAINPKDTNTFATACLDRTVKIWSLGSPHANFTLEAHETKGVNYVDYYPHSDKPYILTTSDDRTVKIWDYTTKSLIATLEGHTNNVSFACYHPEIPIIVSGSEDGTIRLWNANTYRFEQSLSYGLERAWCVSYQKGKQGIAIGYDDGAVVIKLGREEPAVSMDASGKLIWARHNEVVSAMIKGGDASIKDNTPITVSTKDLGTCEVYPQTLLHSPNGRFVAVCGDGEYIIYTALAWRNKAFGSALDFVWGSKENSNDFAIRESPSSIKVYKSFQEKAGGLDVDFMADGLTGGILLGVRGQGGISFFDWQTGGLVRRIEVEPKHVYWSENGEMVAIACEDTCYVLRFSRENYMAAVQSGEVEEDGVEAAFEVISDINENVQTGEWVGEVFIYTNHTNRLNYLVGDQTYTISHFDQPMYILGYIQRDGRIYVADKDVGITSFALSLPVLEYQTLVLRGDLESAAELLPSIEGEQMNKIARFLEGQGHKDLALEVATDPEHKFDLALSLNQLSVALELAKESKAEHKWKVVGDAAMAAWDIKLAAECFTLAKDLGSLLLLHSSTGDRASLLALAEQAKNAAAHNIAFTCRWLLGDVDECVELLKTTNREAEAVLFAQTYKPSLATDAARTWKQSLEKNKKARVAKLIGVPGEDEDLFPAWDEYLRLEAEGGSVSDQGAEEDVEAESEKDEVEGETEAAAEASSEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA93</accession>
    <name>A0ABR3ZA93_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_002508</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the pacC/RIM101 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000049">
        <property type="protein sequence ID" value="KAL1897187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050806">
        <property type="entry name" value="pacC/RIM101"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47257">
        <property type="entry name" value="PH-RESPONSE TRANSCRIPTION FACTOR PACC/RIM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47257:SF1">
        <property type="entry name" value="PH-RESPONSE TRANSCRIPTION FACTOR PACC_RIM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="43"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="79"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="109"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="328"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="463"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="523"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="381"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="479"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1897187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="566" mass="62240" checksum="47389B2B76376A33" modified="2025-10-08" version="1">MSSGRLDNNPIGSSSPSAKSDTPNPISATTSHTSTSSSSEEVLTCRWNACNQQFATPEILYDHLCERHVGRKSTNNLNLTCQWNSCRTTTVKRDHITSHIRVHVPLKPHKCDFCGKAFKRPQDLKKHVKTHADDNVVARQADQSSLGLGGYRSQSKPVGTPYYDHNSHMRAPQSHFPQAGHPNYYGTPQPSTHYGLYFGQPPLGRSYEMGHNTAPAFDDRKRQADAAVDGFFGNVKRRHVEPNSYAQISRSLLPLHGMVSTMGNGSDYMTQHAPGVHSVNQTTTNGPSPLAQTYYLPAMPNARTQKDLLQIDQILEQMQNTVYESANQTTQGIHVHSSHPDARHSHSPPSMNRGSAHGGMMSHAYHHQNQMQHAPGHMHSPLTSISTGTPVATPPSATMSYTSGQSPSPSASDMSPQSRHSSTASGLYPSLPAVNSVIPGQSATATLGPIHDNSERRRYSSGLLQSGKHSARRMSIDSNHSDASDTDSETREREEVYDRWLEDMRVLEKLRTYVKLRLDSQNFDDGESSRVDSPALSDHTETEESELVTSRPSTPPVPLYPTLSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAS4</accession>
    <name>A0ABR3ZAS4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000040">
        <property type="protein sequence ID" value="KAL1897760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33481:SF1">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33481">
        <property type="entry name" value="REVERSE TRANSCRIPTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="77" mass="8674" checksum="62F324E25A5DB6FD" modified="2025-10-08" version="1" fragment="single">MAPLYRKLPNLLGYADDGAMIIDGPTFEDNCLNIETFMKIVIDWTTQNGLELDQEKTGLLHIKGRKRTKGNPPVTIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAX9</accession>
    <name>A0ABR3ZAX9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7708 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_002159</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000039">
        <property type="protein sequence ID" value="KAL1897816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056125">
        <property type="entry name" value="DUF7708"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24809">
        <property type="entry name" value="DUF7708"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7708" evidence="3">
        <location>
            <begin position="122"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="491" mass="56249" checksum="98DEF8A1D19262AD" modified="2025-10-08" version="1">MNKLRLRKRAPQEHSYERPRKPLVTQPNGPGVLFIPWYSKTTDYCYYNVVQTTCKATKQKILQLRTIPEERELLLNPPATIEGIKERLYRLAEDKDKNRQRHSDRSVQRSLDFRSDFLGIIHQMSALATILVPVVAEANIVIGMMMIIFRVVVNRREREDALLDKLRDMSPKLPNPDMYTSMEPDNTCKMAAARLFVGLVGFTEILLFQFRYIRTGKLFSALVSSLQDNLADCLDNMEAKSTAFKHATYRILRENSDVDSSTQSSKKQANLTDKMSQSIMATLETLDVRVTALEKTASQISRFTMVQYSQNLISALMANPIEVYWNPEESLVHTGSHHWENNEFLKALSGWRDHPKGPLVWIGSSSDVQQQPLLLHSRPNIAYETPEFFTINLFQRAALSFTALWEILERLVEALSDDVYIIIDRIDKVQSDDISQVTNDVIRSMIALANKLPRAQVLLTSVYEPPLELPSYQQAGSMEVFHIHAQQGRLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB67</accession>
    <name>A0ABR3ZB67_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome b-c1 complex subunit 2, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Core protein II</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">QCR2_1</name>
        <name evidence="14" type="ORF">Cpir12675_002273</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peptidase M16 family. UQCRC2/QCR2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000043">
        <property type="protein sequence ID" value="KAL1897545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050361">
        <property type="entry name" value="MPP/UQCRC_Complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851:SF209">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851">
        <property type="entry name" value="METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="12">
        <location>
            <begin position="49"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="13">
        <location>
            <begin position="195"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1897545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="446" mass="46301" checksum="3885A89C4AF87B5C" modified="2025-10-08" version="1">MISPISASRLARQSSRIANQAVQRRAISTAGSYETYTAEGIKTASRDVRGPTSKVAVVAKAGTRYQPLPGLTVGLEEFAFKSTAKRSALRIARETELLGGQLKSYHTREALVLEASFLREDLPYFTELLAEVISQTKYTTHEFHEEVESVIRQKQGALAPSASAAALDTAYSVAFHTGLGSAIYPAAASTKSYLSENTVAAYAEAVYNKSNIAFVVDGAAQPIVNKWAEVFFKGIPAAAGSNALSINTASTKYFGGEQRLSHSHGNSIVIAFPTASAASAQVLASLLGGQSNIKWSTGFSALGKINAKIPGLSISTANSGFTDAGLLTITLNGSSTAVSKGAIETVKALKTIAGGAINAEDLAKAVAQAKFAALDATQTSSGSILTAASGLLFNAPSVAAQVKAIEAVKADQLAKTVKALLEKKATVATVGDLHALPYAEEIGLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBY2</accession>
    <name>A0ABR3ZBY2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HAUS augmin-like complex subunit 6 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002313</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000044">
        <property type="protein sequence ID" value="KAL1897525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028163">
        <property type="entry name" value="HAUS_6_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14661">
        <property type="entry name" value="HAUS6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HAUS augmin-like complex subunit 6 N-terminal" evidence="2">
        <location>
            <begin position="105"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="490"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="663"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="733"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="854"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="523"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="563"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="582"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="609"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="783"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="802"/>
            <end position="813"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="875" mass="96490" checksum="36B18F665E019270" modified="2025-10-08" version="1">MPTSPSTTAGLVRTRSLRPPKTIAPTSINNNTTATATASSSKINSYSTRNPALIRRTADSITSGSTLASVTPVESSEAQHHPTNPTGARQQPSGSSGPSRCLKLFLANLRALDLDLRPDWPDISPLTFASSASSLGQKKRVQSVEWALFYLFKLWDPEECRTKLQLLFPPNDQVQSLNLRAALLRCLDQAKKNGVLSREMIIRKTMLDDCKGERLEEVLAGFSAAVLKRVIAENPHSRCPAIAQTLALENRGISGEGEQIPALILAHKASLSRQLREKQKTQGLYQDLSELLDVKERTLARRQEQLEAVMPSEAVTPQQKTEVNRMVRNNWAGNDQWMEALLHGDGAEASKDPFLNTPFDKVWRRLHAGRLSELEEKPKSLLGQLDLRIQAQQERLAKWQDFQERIFGTSENRPINTNPVSTRRTSRCTIDLHFTAHPDLSSASAVASSHRKADNSLVTTFPTMIVETGDYSSLIRDFYADIAAINGTKHTSLSSQSRMRKDPPRKPHRSPIASQEPIFTANSSSSEDPASSRTSESPTSCHIRSGSIKSPPRMSLPRVTLPSVPTTDSVEPSLQLHPPRSSWEKSVERPIRVRRGDETPVRKLGPRRMPSPKPPPKIGAPGSSKEKGPGMFPGLRKLSGSIMGIKPSSGISVDSRVSTKIITTSMETKKPTPVAVLSPGSEPPRDTQTLDGQVEEILEAMQNASPSPTRKIQPCRTMSLADRTRLSIMKTTSFDLDLDQDTNPEQSSPSVEVHAPEIQPPDNEPMGDLVARTRNSMAGFEAAQKKAQVDRRRSLRLQRTASRKDKGKSRFDDVPEECLNVPQTGDVLDADEELSHEMSFLGLMDSQEDYEAVFRSRPKIKTSPAPSPSRMGFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCF6</accession>
    <name>A0ABR3ZCF6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Asparagine-rich protein (ARP protein)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">NRP1</name>
        <name evidence="9" type="ORF">Cpir12675_001916</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000033">
        <property type="protein sequence ID" value="KAL1898371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06133">
        <property type="entry name" value="ERI-1_3'hExo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12452">
        <property type="entry name" value="RRM_ARP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047201">
        <property type="entry name" value="ERI-1_3'hExo-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034351">
        <property type="entry name" value="Nrp1_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23111:SF40">
        <property type="entry name" value="RNA-BINDING PROTEIN INVOLVED IN HETEROCHROMATIN ASSEMBLY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23111">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00641">
        <property type="entry name" value="Zn_ribbon_RanBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="253"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="8">
        <location>
            <begin position="352"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="8">
        <location>
            <begin position="436"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="492"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="574"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="496"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="574"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1898371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="627" mass="66819" checksum="D843B25E35745E7A" modified="2025-10-08" version="1">MAAQQPPSGNIDRYVVMHVATTCDEHGVYVTKDSAEVIELGWIVLDAKSTDEVARDSVLVKPINTPITPLCTSLTTLTWEHVRGAGTFRDAVNHFDAFINEHLTSKNLDFVFVTLDAWDLRVQLPREARDKAVVLPPYLQHSCTFDLRTEYQRWQQHHPESLPFGPSMLSNICAALEVEPVQSSAPIKHNLPFHLQALAPASPRRAIEEAITLARVLRGLIRKSQPAHGHPDVLTRPMDARADVRAFLSERSKVLHMSGLPHDTTQSELESWFTQYGGRPIAFWTLRTPEQHKPTGTGFAIFSSHEEAAESLCMNGRALNEKAIEVSPSSSRVLDRAADILTPFPPSKNRPRPGDWTCPSCGFSNFQRRTACFRCSFPAIGNGPMGEMGGFGGYGGGGFNGPPNMMHSHHNISHHNHGHMGHGGGRMGGGGVVPFRAGDWKCGNEICGYHNFAKNVCCLRCGASRAGAAIVADSGYSSNMNSGNNYSNMNQNTMGGNNGPPGGPFGSQGGGDYGGNGQHFGGPLSTYALPNVIGGGGAATYPSSLNAHFGHGPGNHSAGPFDSRAAEAAFQSANNGPANVGQSSNFYGNNNEGDPFSFLSSGMGGLSVSGGDARQNGGAAPPAKSPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCG0</accession>
    <name>A0ABR3ZCG0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6699 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002245</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000041">
        <property type="protein sequence ID" value="KAL1897746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046522">
        <property type="entry name" value="DUF6699"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20415">
        <property type="entry name" value="DUF6699"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6699" evidence="2">
        <location>
            <begin position="66"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="176" mass="19768" checksum="2A4A0199A2DF3C86" modified="2025-10-08" version="1">MSETLAPLSKVDSAVDGVHDVPHNKTQKHRRSSSSVSGVFNILDLERERTELTLPIETQRTGWKINSSPNTIEDTSILKLPLVTPPVKKIDLHFPLGMEVTARNMKGVTIKDAMDAIHKAYKKRTDDELESPYLAGFEWDKEECWTRLVVHLQKNSSFAGAANSNSQKKKSKKNSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE62</accession>
    <name>A0ABR3ZE62_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nitroreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000028">
        <property type="protein sequence ID" value="KAL1898928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02140">
        <property type="entry name" value="Frm2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="entry name" value="NADH Oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033877">
        <property type="entry name" value="Frm2/Hbn1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43035">
        <property type="entry name" value="FATTY ACID REPRESSION MUTANT PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43035:SF1">
        <property type="entry name" value="FATTY ACID REPRESSION MUTANT PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="FMN-dependent nitroreductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="1">
        <location>
            <begin position="15"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="205" mass="22685" checksum="04E3ACD803D32B22" modified="2025-10-08" version="1">MATKATADTLISLMTARRTYYALNKTLPISNDRVTEIVKEIIKQTPSSFNSQSTRAVILFGAEHEKLWDFATAELKKIVPSENWKTTGDKLSGFRAAAGSVLFFTDNVPVKALQEKFATYAPKFPGWAIQTNAMSQFATWTALEAEGLGANLQHYNPIIDAQVASEWKIPENWTLDAQLVFGGIAAETYPKDFAPIDERVKSYGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEB5</accession>
    <name>A0ABR3ZEB5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transcription factor CBF/NF-Y/archaeal histone domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_001796</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
            <location evidence="2">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the CENP-W/WIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000030">
        <property type="protein sequence ID" value="KAL1898689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13732">
        <property type="entry name" value="HFD_CENP-W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052484">
        <property type="entry name" value="CENP-W/WIP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34832">
        <property type="entry name" value="CENTROMERE PROTEIN W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34832:SF1">
        <property type="entry name" value="CENTROMERE PROTEIN W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0137">Centromere</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1898689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="82" mass="9212" checksum="FFE7E194F49C707D" modified="2025-10-08" version="1">MAPGRKLYPRGTIKKIVKAHSNCNLTKNADVLLGDEIFLDYMMFMEKLVKEASIETRKKGERNLTPASVNKVVADSLLKFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFA5</accession>
    <name>A0ABR3ZFA5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000026">
        <property type="protein sequence ID" value="KAL1899060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="188" mass="21119" checksum="19BD541041A14177" modified="2025-10-08" version="1">MPSTRKRKQDDKDDEGDDEELLSLPEYVSDEEEEDDHFNEDEDDISDDDEDEEDGENDDEEDGENDDDGDEETGDEKDDNQSDEKDDNQSDGAAKQTQELDLEDDPPVKKRKIATADEDKANKEAENAREDGDKKNDREGEERDNAQGDVDSNDAEGKVAVTVEDEKDSKATENKQPAVEEVIGSDQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFC9</accession>
    <name>A0ABR3ZFC9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ilp is an apoptosis inhibitor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001443</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000022">
        <property type="protein sequence ID" value="KAL1899406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053267">
        <property type="entry name" value="Verrucosidin_biosynth-assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42087">
        <property type="entry name" value="ILP IS AN APOPTOSIS INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42087:SF1">
        <property type="entry name" value="ILP IS AN APOPTOSIS INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="241" mass="26580" checksum="A7F66BD281929BC7" modified="2025-10-08" version="1">MSHLFKPFSNYIFLMIANGIFGLPQPFLGNSDIFDWHPKFQSCVRYFLDVAQHTSPVQAVAAYVNIQLPSQRPRQQILSSAQVLPHTASPGPAAGGSSPSARTAMSMSMSIPPGSPTSYVTAGAAPSTVTLLPYIRRLVATGFDAPGVLHGFFGDDWRGGVGPLHEAERQNYLFAAKSDTWLHVKADYDMDDGQTIPFMRPLNATEEEIEGAEASWSEWLAMQDWMLGPRAPQIRVKRERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFF9</accession>
    <name>A0ABR3ZFF9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_001406</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000022">
        <property type="protein sequence ID" value="KAL1899371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12241">
        <property type="entry name" value="RRM_SF3B14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034150">
        <property type="entry name" value="SF3B6_RRM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="14"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1899371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="116" mass="13292" checksum="E2358949A10EB4A5" modified="2025-10-08" version="1">MNNRGGKSAPDVNRALFVKNLSYNVTPEDLFDLFGKFGPIRQVRQGIANNTKGTAFVVYEDVMDAKQACDKLNGFNFQNRYLVVLYHQPEKMVRSREDLEVRKESLAQLKQQHGID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFV5</accession>
    <name>A0ABR3ZFV5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein png1</fullName>
            <ecNumber evidence="6">3.5.1.52</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">png1</name>
        <name evidence="6" type="ORF">Cpir12675_001358</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transglutaminase-like superfamily. PNGase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.52" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000021">
        <property type="protein sequence ID" value="KAL1899590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000224">
        <property type="term" value="F:peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.620.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050883">
        <property type="entry name" value="PNGase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143">
        <property type="entry name" value="PEPTIDE N-GLYCANASE PNGASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143:SF19">
        <property type="entry name" value="PEPTIDE-N(4)-(N-ACETYL-BETA-GLUCOSAMINYL)ASPARAGINE AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Transglutaminase-like" evidence="5">
        <location>
            <begin position="244"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="40"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="402"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="62"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="402"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="424"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="449"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="462" mass="52858" checksum="84152C892836D839" modified="2025-10-08" version="1">MNDQTQDWRQSGNNSTYGEEWARDLRVKFESLLKEKRMNDFRAAQRQGSPAIHDSSDSSARSPFLPSTSSPSPMAAHSFNSPPNYSSVRYLPKIPVPPNADDRESQVFRSMMISLALTPTKYENPGLLDEALQTIPLDRIYAEAEEESQLMRAQAESLGQDRPEWGYQDCVIRALLRWFKRSFFSWVNNPPCPACHTPTVAQGMTQPTPEENACGALRVELYRCSNGSCGAYERFPRYGDVWRLLHTRRGRVGEWANCFGMLCRAVGGRVRWVWNAEDYVWTEVYSEHQNRWVHVDAVEELWDRPTIYSEGWNKKISYCVAFSIDGATDVTRRYVRKSECAADRTRCPEEVMMYIMQEIKNIRRQNMDKNERVRLQKEDMAEDEELRGYVVASIAMAVTNIKPRSSSSAQNSRPGQDIKMPAEQQLLQQQADQANWVAAQNPNYQPGRFSGGGFPPQGPHGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZG02</accession>
    <name>A0ABR3ZG02_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Ribosome biogenesis protein NOP53</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_001640</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">May play a role in ribosome biogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
            <location evidence="5">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
            <location evidence="5">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the NOP53 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000027">
        <property type="protein sequence ID" value="KAL1898980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011687">
        <property type="entry name" value="Nop53/GLTSCR2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14211">
        <property type="entry name" value="GLIOMA SUPPRESSOR CANDIDATE REGION GENE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14211:SF7">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN NOP53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07767">
        <property type="entry name" value="Nop53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017302">
        <property type="entry name" value="Gltscr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="249"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="277"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="307"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR017302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="441" mass="49728" checksum="B35EB352AD32EB03" modified="2025-10-08" version="1">MPVIQGLSAAPSAPAQHKQSSRKGKKAWRKNIDVTEVEQGLEERNEQIIQGGILAEKESEDLFDIDIKGDAASKKSIPTRLRGLKADEIINQRSAVPSVSLRKRPAANSKVGDGLVDTKRLRKDWVSHKELSRLRRVADGEREFLEVKDASYDLWDAEPVTTSNDEEFNFIPKPSKAKLPSTMKEQPVSLAANGKAIPAVKKPTGGFSYNPTFDDYTNRLDTEGAKAMEAEKKRLEQIEIDRQRAEAAARSAAEAEAAEAKLDLSEWDEDSAWEGFESGAEDAAGAKASAKRPQRKTQAQRNRIKVRKEEEQSANHERAMKRKQEQLRQLKRIAKEVEAQEQEKLAVEAEAGSSSENEGDDSVLRRKAVSRLPLLEKELEIVLPDELQDSLRALKPEGNLLKDRYRNLLVRGRVDARKRMPFKKQRKGKLTEKWTYKDFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHA1</accession>
    <name>A0ABR3ZHA1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">rRNA-processing protein EBP2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ebp2</name>
        <name evidence="7" type="ORF">Cpir12675_001096</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EBP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000015">
        <property type="protein sequence ID" value="KAL1900093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008610">
        <property type="entry name" value="Ebp2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13028">
        <property type="entry name" value="RRNA PROCESSING PROTEIN EBNA1-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13028:SF0">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN EBP2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05890">
        <property type="entry name" value="Ebp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="24"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="276"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="324"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="24"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="73"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="94"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="109"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="276"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1900093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="408" mass="45674" checksum="A3AC7259F4B14D06" modified="2025-10-08" version="1">MVVKSKLKMALAAEKNTDFKKIKEKRRLKQLHKTKATKTVRPEEPNEEWEDEEPDSDSEQDESANGINYEALNESDSDDSEVEMEEKIERVKKTAQTPATAPAKASKNDEDEDEDEDEEDIPMSDLDDLDDEDKEDLMPHTRLTIYNKDALITSLNRIIVPSDASVPFVSHMCVVSPTPTTSAIADVSDDVQREDAFLAQCLAAVKLARSKLVNDGVPFTRPTDYFAEMVKSDDHMGKIKDKIVAEASAKKASAEARKLRELKKFGKKTQVAKIQERAKEKRETLDKIKNLKRKRQENTNDVGTHEAGEFDVAVDNELKTFRNKSEANGRFSGNGPNAKRIKKNDKYGFGGKKRHLKSGDSKSSGDLSDFSQKRNKAPFSSTSAGGGKKRVPTQRLGKARRKAIASRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI07</accession>
    <name>A0ABR3ZI07_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">High-affinity iron permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">FTR1_1</name>
        <name evidence="8" type="ORF">Cpir12675_001168</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000017">
        <property type="protein sequence ID" value="KAL1899947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004923">
        <property type="entry name" value="FTR1/Fip1/EfeU"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31632">
        <property type="entry name" value="IRON TRANSPORTER FTH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31632:SF2">
        <property type="entry name" value="PLASMA MEMBRANE IRON PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03239">
        <property type="entry name" value="FTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0410">Iron transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="296"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1899947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="372" mass="40936" checksum="3F2E4B4D657BCEF1" modified="2025-10-08" version="1">MAELDLFSVPVFLLIFRETLETAIIVSILLAFLKQTLDVPDGDPKVYRALRRQVWAGTAIGFSICLCIAGGVVMAFYSWNSTTWDQNELYYESFFSLFASLMITVMGAAVLRVGKMQAKWRVKLAKAMHAPVAVGEGGWFGRLLERYAMFTLPFVTVLREGVEAIVFIAGVSFSTPPSSVPLATLAGLAFGAAAGYALYAGGSGARLQQFLVAATCLLYMVGAGLFTRAVWYWDQQKWNEAIGGEAQELGMGPGSYDIDKSVWHVNCCSPQFEGGGIWGVLNALTGWTNSATYNSVIAYIVYWVFVIGMFLVLRFKELHGRLPLMKRYRVVDPLASDCPTLNCDPDVDRAHRPSGDSTRALLSRRLTNRASH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI40</accession>
    <name>A0ABR3ZI40_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glycosylphosphatidylinositol (GPI) anchor assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GPI11</name>
        <name evidence="10" type="ORF">Cpir12675_001015</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000014">
        <property type="protein sequence ID" value="KAL1900331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009580">
        <property type="entry name" value="GPI_biosynthesis_protein_Pig-F"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06699">
        <property type="entry name" value="PIG-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="110"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1900331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="268" mass="29026" checksum="DB605B9B64CAC194" modified="2025-10-08" version="1">MVTKPARSAPVASNEPETPPPPPLASVKLHTDLIALSIRLGQPMLVAAFFIYNFSNVIADPVEGLQKILAVVAVAQVVYVLACVPEVGTKYKTGAATKKKMERRSSIQRSVFTAILSLILSGLITPFAHLVLILFGGPFLNLVKPTFLCAAHFSLVCMFPLFYAHGVESSTWLAIGSLGQPIDEPYGALCGGLLGAWLGAVPIPLDWDREWQKWPVTIVCGIYMGAALGRLLGGSLMFGRRMVELDVPVKEELESERAFKTMDSKLMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZID7</accession>
    <name>A0ABR3ZID7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000947</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="496" mass="52370" checksum="2C0DAD08780A3676" modified="2025-10-08" version="1" fragment="single">LGFANVIDPGPPTAESCPQDALYSPGEIPCSQPASESALASTSFISSTSISPTTLMSTVARSTTSLDGIHALSIPGASNSGTSTSFRSMTSQRSSTLLSTSSLATGTFLSALSSSATDLFTSAPSNSESSSAPETVAASTDSPDSGGIPVRIRAVIAVCSILAALTIAALVFLLCRRRRRRPTPSISSTPPLLHQRTISSQPSSPTHLLSLPRPMSDPSSAPLTPPLKLRDRQLLHTPPRSMENGPSGQGTFSMPAHNDFPTSPICAPTINILEPRREKVYRLNCSTGSGLITYEHKTPSALETPYVLVTTASKTTSQFRRDSANSIDDSIAFVDEKKAVAPAPILLSPVRPPRPEELLEVPGLVRPNPGSCKLHPRSASSPIIPRPPIPAMHPGRLLSASLSSTSLHRQKQLQAHVRAPVQGETSSGFSDLSKDSQELCDLTKEYASEAKPYRGASTPQKCTGAPGMAFTTPHRTEELPKLRGGVDLEVLAGTYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIR0</accession>
    <name>A0ABR3ZIR0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sterigmatocystin biosynthesis monooxygenase stcW</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_001298</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000019">
        <property type="protein sequence ID" value="KAL1899713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF12">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1899713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="619" mass="69016" checksum="D0D0DB7A947152B6" modified="2025-10-08" version="1">MAFSLASSHIHKLKTRIRRAMSRHLDSSHPQHGNAHSRASSSPESSVSSYTIQNVPIDLPRPVRIITIGAGASGINLIRTLRLKLGDPFEHVVYEKNPQIGGTWYENRYPGCRCDVPSMSYQFSWKKSTDWTNLCASAAEIESYLCAIRDQEGMHSLIKLSHTIVNAAWDEDTAMWEVTVEKLDGSRFVDKANFLIDASGILNKWQYPKVPGLDAFSGQLIHTANWPMDGLSVAGKRVALIGNGASGVQVLPWLAENADSLHHIIRSPTWILPPRVAMMKMGPMAEIIEKIELDDEDNFTAAQIARFKEDTDLYNRLTQAMEDDMHVKFAISLIENSPQEKWASQKCREFMTAMLGGDETLCKALIPDFSFGCKRITPAPGYLEAFRKPSVRLVKNTIAAFEKKGLRMTNGDLIEVDVIVCATGFESSFRPTFPIIGRRGNLQDIWAKEEPKSYMSLAIADMPNFFKFLGPNAPIAHGSVFSLSEHIATYIARVISKARTQNIRAMAPSTGAVEDYHEHVTKFMPRTTWAGNCSSWYKGGKTEGASINALHPGSRLHFIKMLEDFRGEDWDIQYRPAQSGDQKVNRFAYLGNGFTIAEVRNLKAMAAANAAQEEAKARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKC9</accession>
    <name>A0ABR3ZKC9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MCX1</name>
        <name evidence="6" type="ORF">Cpir12675_000725</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050052">
        <property type="entry name" value="ATP-dep_Clp_protease_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102:SF7">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="268"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="Clp ATPase C-terminal" evidence="5">
        <location>
            <begin position="526"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="163"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="383"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="385"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1900849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="660" mass="72585" checksum="6DEBE68AFA3D7B00" modified="2025-10-08" version="1">MTCVRASTSAKSHLGPMTSLAFKPTSPVGLALPPVVTVAFKSHSTNITQSRLRNKGLTISRLAYTHNYGPRLFSSSAIRPSTPRCTRDFGSGFSNSYDPNIESRRGPIFKNKATGVPPFYPRDLKAKVDDYVVGQDRAKKTICSTIFNHYQAVRRRNEFEIEERSTREKLQRQQLARDRELRDLRNADALAGTSGPDQNGRDDDPVYSQYDPEDSTPHEYTMNAPQNPSATLPGAYTRNHIQTTLDIALSSPLQQTENPNMPDHINIDKSNLLLIGPTGVGKTYILETLSKKLKVPFSISDCNSFTQAGYIGQDVETCIERLLIEANYDVKAAENGIVVLDEFDKISRRESNNGRDVGGEGVQQALLKLVEGSKVTLNIKDTRPSRTATPIPSTYGSVPPPPSLPPQGGQSGKTEQYIVDTRNILFVFCGAFVGLDKLILRRVSRPVLGFGADVKSGPKSRGAGPDVLPLEMYSHLPHQPIQHPGSADPSSKFSPLDLTTPADLQAFGFIPELIGRVHNICALSNLSVDDLYRVLTEPRNCLVSQYTALFETYPSRLFFTRKALRTIAERAAKSGTGARGLKMEMERVLSEPIFDAPMPYVLITEACVNGTEKAGYWGKDGRFEVERQMADEDKLEGNATGLEDMIVDDQQSKIAGLGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKF8</accession>
    <name>A0ABR3ZKF8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein Asterix</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_000852</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005351">
        <property type="entry name" value="ASTER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28038">
        <property type="entry name" value="ADL329WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28038:SF1">
        <property type="entry name" value="ADL329WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03669">
        <property type="entry name" value="ASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1900717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="116" mass="12953" checksum="C135A39CDEBEA545" modified="2025-10-08" version="1">MSARKDQRRVDLIVPYQEPAPKDNETVDLSSSLSSTMPMAAMMTRNRYFGWGSFFFSMQNWLGESESTRKSNSTPGYFSVIMSFMALVVTYLPMFMPPPIARGSNTEAPAPVAPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKJ2</accession>
    <name>A0ABR3ZKJ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_000587</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF14">
        <property type="entry name" value="MFS GENERAL SUBSTRATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="206"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="353"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="423"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="449"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="480"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="515"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="11"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="574" mass="65613" checksum="F4C5536893D7F8DC" modified="2025-10-08" version="1">MTSWPWSRSLKPRDGADSYSSRHEDDSKAPNITSAPSKRTSSIATSSSHDVVSQATPHILGSTPNHAFSSPSMAEYWRGVYDKAQYENRHRFDPTFEWTADEEKKLIRKIDIRIVLLAWVMFCSLDLNRRNINRAISDNLLPELNMTTNDFNYGQTIFLTSFLAAELPSGLISKRLGADRWIPALITCWSIVSGCQAWMATKTHYYVMRCLLGLAMGGFIPDVVLWLTYFYKSNELPKRLAFFWTALSTCNILGSFIAGGVLQMRGVASYSGWQWLFLIDAALTIVIGLLSIGLMPAGPCQTSGWLRGAKGWFTEREEYIMVNRLLRDDPSKGDMNNRQGVGLALLWKVLKDWEMWPLYLIGLTSYIPPSPPNTYLSYILRQLGFNTFKANLLAIPSQFLFAIQLLVISWVSEKVKERSIVSSLSNIWILPWLIALVVVPASTSAWVRYVLLSGLLSYPYCHAVLVSWNARNSNSVRTRAVSAALYNMFVQAGNIIATNIYRDDDKPLYRRGNKILLAITVYNIFQFYLVKLFYIWRNKVRERQWNAMSKEEQEDYVRSTTDEGMKRLDFRFAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKT6</accession>
    <name>A0ABR3ZKT6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pectate lyase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_000778</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the polysaccharide lyase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002022">
        <property type="entry name" value="Pec_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045032">
        <property type="entry name" value="PEL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683">
        <property type="entry name" value="PECTATE LYASE 18-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683:SF18">
        <property type="entry name" value="PECTATE LYASE 21-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00544">
        <property type="entry name" value="Pectate_lyase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00656">
        <property type="entry name" value="Amb_all"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046382108" description="Pectate lyase domain-containing protein" evidence="6">
        <location>
            <begin position="19"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="Pectate lyase" evidence="7">
        <location>
            <begin position="267"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="35"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="66"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="118"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="156"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="200"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="237"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="541" mass="55324" checksum="8CBDC8FC63AD8CA3" modified="2025-10-08" version="1">MHSRVFVSLLAGAAASMAANIPANHGAVAHAARQAADCPAPGSDEQPTTPSVNPMGSYPTGIYPAGSFPTGGFPTGGFPRTMRTRTRTRTRNGGYGYGGDSTPTPAPTSGGSVEAEATDEKEAEKEAEKEADAENDYGYAASSTSEPTVYSAKPTSTKKAKTTKTKKVKTTSGAAPLGTGTGSASSSEPEYNSEPDSNSEPDSKSSSDYGSGYTYGSGPGYYATSTTPDLPASTGSSGSGGSSGSGGSTNSGDGTIIGYGAGTTGGGSGAGTTVTSCAELTSAAGAGGVVRVSGSLKGCGIIKLISDTSIIGVGADSGCEDTSFVLKDVNNIIIQNLNLHNPPEGKDIITVDKATLVWIDHIAFSSMGTDTGNKDFYDGLLDITHASDMVTVSYNSFKNHYKASLVGHSDTNAGEDTGFLHVTYHNNYWNNIGSRCPSIRFGIAHIFNNCYEDITTSGVNSRMGAQVLVEGNEFINVVKAIMTNLDSSEAGFAIDKDNSFTNSVIDITQTCDYSPPYQYSAAPGAGVCASVKASAGPNAYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLB1</accession>
    <name>A0ABR3ZLB1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sporulation protein rmd1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RMD1</name>
        <name evidence="5" type="ORF">Cpir12675_000701</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RMD1/sif2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003734">
        <property type="entry name" value="DUF155"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051624">
        <property type="entry name" value="RMD1/Sad1-interacting"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255">
        <property type="entry name" value="REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255:SF15">
        <property type="entry name" value="SPORULATION PROTEIN RMD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02582">
        <property type="entry name" value="DUF155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="515"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="DUF155" evidence="4">
        <location>
            <begin position="316"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="104"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="107"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1900825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="541" mass="60752" checksum="D302FB89FD27A1F5" modified="2025-10-08" version="1">MSTDPSSASERSPLLHSLQSPPSSQDPPPSSSSSLTTPEANVAPHHSSKQTRTVSFDPNPVTRTFEVEALEHRRQRPRPSSQSPHGLGGAPVMAALNLNSKLRRRNSSTPSGTSPASSALVPPIAPVPKIGPQRTTKNAQKLKILPNPEVDDGDQDYESGRDVYSQYTRIKDPTARRDAARLGKADRNRLPRVTAYSTAEHFNMEAILRFLKGKKKRGGNPKFFDECIYSPYSYTHLINEVSYSSTTAHGHGPANDHYIQHPDDPVQAYERRHSTGSDMDGNYNRTDLLNLSPENCDDLAIDDTPTLDTKVHTPEVFVFEYGVVVIWGMSEIDEKRFLKEIAKFEIDPRSKDAIQLELFNFYYTNEYQARIYNDFITLRDRQNYMIKLAISHALAQSVQTSLFEDLVGLAIEECKDIPSQIALTGKIDLSRRQINMAIADLFNLRIGIHLTGSVLDTPELFWTEPHLEPVYQAVREYLELDQRLNVLTDRLDVIADLLAVLKEQLSHGHGEMLEWIVIILVAMEVVVATINIIVDLYVSPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLC7</accession>
    <name>A0ABR3ZLC7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Protein kinase C signaling pathway involved MAPKK protein</fullName>
            <ecNumber evidence="9">2.7.12.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MKK1</name>
        <name evidence="9" type="ORF">Cpir12675_000716</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.12.2" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004708">
        <property type="term" value="F:MAP kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06621">
        <property type="entry name" value="PKc_Pek1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050915">
        <property type="entry name" value="MAP_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47448">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE DSOR1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47448:SF5">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINAE MKK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="224"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="156"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="109"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="159"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="175"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="516" mass="55661" checksum="E5F66FBA8D26B7DC" modified="2025-10-08" version="1">MADQASSHPTPADSLTVKPLMPTPPAAGPSIPNLGVGPPMLRPALGGARSANRTPRLGLSIPTPPSAKPVNAPGSRPVLPTLKVATPQGSKTTPYEQPPRLATNQLNQSASGGSESSAAHSRSGSFGPLDGRASNPTSAASQFSALSFASHFGIGVTRPQGTPDPTSAAGSLYSERSETMERDGSTQAIEKGMDKLSLMEKIRDKDVEELDDEGWRIASSVDRIVELGSLGEGAGGAVTKCKLDGGKTVFALKVITSNPDPDVKKQILRELGFNKNCASEHICRYWGAFVDPSTATISIAMEFCEGGCLDSIYKEVKRLGGRTGEKVLGKIAEGILGGLTYLHSRRIIHRDIKPSNILLTRKGQVKLCDFGVSGDFGTKGEADTFIGTSYYMAPERITGQSYTITSDVWSTGVTLLEVAQHRFPFPADGTEMQPRAGLIDLLTYIVRQPIPRLKDEPDGGLVWSDSFKYFIECCLEKDPARRATPWRMLEHPWMVEMKTKRVNMEKYLAQVWGWDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM25</accession>
    <name>A0ABR3ZM25_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PUP3</name>
        <name evidence="5" type="ORF">Cpir12675_000218</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the proteasome complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase T1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03759">
        <property type="entry name" value="proteasome_beta_type_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033811">
        <property type="entry name" value="Proteasome_beta_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF10">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1901711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="211" mass="23404" checksum="DCC86D427FD350A3" modified="2025-10-08" version="1">MYRSHPVPSLEHQNGGACVAMVGKDCVAIACDLRLGLQALTVSNNFPKVFQFGDVFLGLTGLATDVITVSDLFRYKTNMYRLREERNIAPRTFANMVSSSLYERRFGPYFVSPVVAGLDPKTSQPFICGFDSIGCIDFAKDFIVSGTASDQLFGMCENLWEPDLAPQDLFETVSQAMLNAVDRDALAGWGAHVYIIEKDKVTLRLLKSRQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMD9</accession>
    <name>A0ABR3ZMD9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000607</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046659958" evidence="2">
        <location>
            <begin position="21"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="294" mass="33609" checksum="B0A6D417A67A1A20" modified="2025-10-08" version="1">MISLSALLPLALLFPNLAQASILEDHDYQVMRSGTTDYVLFRDEYGQNQLLDMFTIYPLMGVSIIHYADNGKEPEHSEKLGLAEIYNALAEERSINLDEIDWVVCEADKDPEAAQLIRQIRQGRGLVLTEDVSIFPADEEWNKILDTKYFKQAAMVNYKMLSKIIIKSHPHEYLRMNFPMDAFYFYFPKWDAFSEPESTNNEEAIDEESELELGDESGNESENEWADEWAHRLQEEWKQERAGDQEIEGREGAAKRAVLAGNDRELASLAAVYAEVDNLISPNRRNDVASSSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMK3</accession>
    <name>A0ABR3ZMK3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="428" mass="49610" checksum="9FF23FCAABB02A59" modified="2025-10-08" version="1">MAYAIRTEFALCSYCQVSPSVAGVNFRPRTNSEPSACIHEARKKLFDEYEKHSIKKAKKNSHVEKLRTVWLKDDIEKHKQFCRKCEQKKREKALHKEEKRRLKRERKADRQAEKAKRAGAHEAKVKEFIKQVKRQADEEAQKMIETQVKKRVEVEVARRKTLEKERAKKKADEELAAKMVVEKEAKKKAEKELREKKLAEEADKRKTEMEAKKKAEASMRAEEQAKEITLAEKATGKVAKSEAEAKEKAQQMSQALKKECLGSLTSILKREHPSSRYRNLREEQRLRRDSKLDYFDVDGVLHKYKWNGVSYDYSSEAITAGISTSGRRPVVSSSYHPYNGHVFQGGGESHTYPRNLQAPEPKSCHKHNRANCNRPPNSDPNSMFPYKDENGEFTTRSRFSIDSLGDNVVWEYQINGNVWFALHKANKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMS0</accession>
    <name>A0ABR3ZMS0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Outer spore wall protein RRT8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000813</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052786">
        <property type="entry name" value="Spore_wall_assembly"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34292">
        <property type="entry name" value="OUTER SPORE WALL PROTEIN LDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34292:SF2">
        <property type="entry name" value="OUTER SPORE WALL PROTEIN LDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="275"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="316" mass="34933" checksum="81E84BAC3B74DE27" modified="2025-10-08" version="1">MSATDLDVSSAPQPVPPYLNSDVSENKKPGFRRRMVNGASTRITQIIKDDVNSTVDAIKQSHESRSWLYPLKGVIYFACHKSLWSPFVRNLPSLMLVSSVVLAFTFGVVWVPTMAVAFFLTGPLAMISATISTLALSATIIQSIAMTYILPMPLVDVFDATLVLQGHMDLVNAGRQVKPALRGDGHNVLDRMGAVWKWPLRAFSLNAAFRKLVYIPLNMIPIAGPGISVIMQARTGGGECHDRYFQLKGWRDKYTNTFVRANSGSYGMFALVDNLLSIIPFASIMFRYTTTVGAALWAADIEKKRVRMVLPEIDVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMZ9</accession>
    <name>A0ABR3ZMZ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000398</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039970">
        <property type="entry name" value="TF_Grauzone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23225:SF2">
        <property type="entry name" value="AT09679P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23225">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="601"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="629"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="662"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="735"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="495"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="873"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="561"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="904" mass="98792" checksum="E1171EA1B2BEE66E" modified="2025-10-08" version="1">MDPPQKRRKLAPKVPQPPSSSPSQANSHTIPAVASAAIAAETSSVPARVEFERFARHLQDAAMMIQRSAERPNYTSVSALLVRWEDDAAAEEDIVAVEKVLREQYSFETEQWHIPSVANASLKLGVQVTGFLKNSKPDSLLIFYYAGHGFVAPDDQVYWACNTNDDSPKLKWDGIRYLFEDSQSDVLFLLDTCIASATIPPQSGNMGVKQVIAANTAESWTREPGKRSFSSYLCESLHVFASTKTPFSIQSLCEDVVARQGVDLSSSAPNGDMGLNAVISAATATNNPSTPVCFTTTQGKWPNVVLSSALADGVSPPCNLSQLKVPKPDPEQPRAVPSNSAGSLSITPEAVVELKFDEPRVLACTTFVGEASSDMTFFNTWLAERPEIADMVAVEAMFFGPPTMLLISMAMPIWEVVRHDKVCIFLGYIGSHNFVHLYQNLVGFTGSRRTQNTVSKEVEDGRILLEAHEAAKRNSIVGEEIAAPETPFRKATLAREGATVSSDDPMQEVHYQPKDDVEESAEMKEAAEQLKALSHTRHPIPDTTLTPQQQNRRRSTLPDSAPERREDGLEPEIKQEETPESATRPKAQRRSIPKAAPRNDTRCTLCSHLPFKDSSSLRKHIAAAHTRPFPCAFFFAGCSSTFGSKNEWKRHIASQHLCLQYYRCSACPASAAEGKFNEFNRKDLFTQHLRRMHAPFAIKKNAGKADARLQADWEATVKEMQQSCLVQRRLPPQRSACPKADCQSIFEGSTSWDEWTEHVGRHMEKSEAQGMGIDRNLAKWALDERIIERDENGEYKLVPDVTYSGRHHEHHHQPITLPTVAASTTVADAPPTSASVATGSGAGRAIALDPPTSVAGGATGPGSGAAAAAVAAVAGSSPSDQKRKRSDWRGELAPLGSMEIDEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN70</accession>
    <name>A0ABR3ZN70_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Amine oxidase</fullName>
            <ecNumber evidence="7">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_000034</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <cofactor evidence="7">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="7">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="PTM">
        <text evidence="7">Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the copper/topaquinone oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.20">
        <property type="entry name" value="Copper amine oxidase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000269">
        <property type="entry name" value="Cu_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015798">
        <property type="entry name" value="Cu_amine_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036460">
        <property type="entry name" value="Cu_amine_oxidase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016182">
        <property type="entry name" value="Cu_amine_oxidase_N-reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638:SF91">
        <property type="entry name" value="AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638">
        <property type="entry name" value="COPPER AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01179">
        <property type="entry name" value="Cu_amine_oxid"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49998">
        <property type="entry name" value="Amine oxidase catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54416">
        <property type="entry name" value="Amine oxidase N-terminal region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0186">Copper</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0801">TPQ</keyword>
    <feature type="domain" description="Copper amine oxidase catalytic" evidence="8">
        <location>
            <begin position="259"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="domain" description="Copper amine oxidase catalytic" evidence="8">
        <location>
            <begin position="667"/>
            <end position="708"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="746" mass="83328" checksum="F0FC2FF8083A5153" modified="2025-10-08" version="1">MHSPASHRHPLSPLQPADFSIARSVVTAARGPHVLLYFREIFLQEPLKNELIPYLIAEHSEKLAADLDAVRPPRRAKVQYDVISGHSHQYTQSIVDLDSAEEVQVVRAKPHQQPSEEYKAFEKACFASSLFQAAVDEFLIPDYFTLKIDPWPYGGPDGGDELLLPRYMQGLVYAQDTRSGNPDSNHYSYPVPLIPVVDWTTRTIVRVDRLSLDPSRHGWISNPSSHTEKIAMFTNASPAEYVPELLPENIPLRTDMKPIEITQPEGTSFRVTTDGLVTWQKWRFRVSFTPREGAVLHDVVYDGRPIIYRLSFSEMTVPYGDPREPYHRKQAFDFGDGGIGRAANNLRLGCDCIGAIHYISALLATADGRSAESRNVVCLHEQDNGVGWKHSNFWTNRPIVTRLREFVVQFIITLANYEYVFAYKLDVTGNIGVEVRATGIVSIAPISPDVVTTTHGAIVAPGALAQNHQHIFAVRIDPVIDSYTSGHTCIVVEETHTDPIGVGLNMHGNGFSTRRRVVTRAEALDAAPEHNRIIRLENRFIQNSVSSRNVGYKFMPLPTQLLLAHPESRQAKRAQFATHHVWVTGHRDGELWAAGEYTNMSESEAGGVRDMVNRGDWFVEDQEILRESVNGARSLIAVEGKLRSAGDEKNPFGLTPQDQASPCLSSPVVWSVFGLTHLPRMEDWPVMPTEIHSFQFRPADFFTYNPALDVPPVPSATSVLVPAVIETQEKIGKIRAAERNGCTSCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNK3</accession>
    <name>A0ABR3ZNK3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glutaredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">GRX3</name>
        <name evidence="6" type="ORF">Cpir12675_000247</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03028">
        <property type="entry name" value="GRX_PICOT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02984">
        <property type="entry name" value="TRX_PICOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033658">
        <property type="entry name" value="GRX_PICOT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="GLUTAREDOXIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293:SF73">
        <property type="entry name" value="GLUTAREDOXIN-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="105"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1901739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="266" mass="28700" checksum="BFAF075891AC8B0D" modified="2025-10-08" version="1">MTKVTEITTQEAWDQHLASVPASSLLVISFHAPWAAPCKQMAIVIETLASEYAPETSSWVSINAEELSDISEQFDVTAVPFIVLMRNGTVLESVSGSSATRVRAAVEKHSANESSGSATTTAATGAAQSSATPTANGVAAQDTQAPEPPVDPVKAKEELFARLKDLVKAAPVMLFMKGTPSSPQCGFSRQLVALLREKSVKYGFFNILADDEVRQGLKEYADWPTYPQLWIDGELVGGLDIIKEEIENDPEFFKAYSVKQSEEATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPI2</accession>
    <name>A0ABR3ZPI2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RPL19B</name>
        <name evidence="7" type="ORF">Cpir12675_000176</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01417">
        <property type="entry name" value="Ribosomal_L19e_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01475">
        <property type="entry name" value="Ribosomal_eL19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035970">
        <property type="entry name" value="60S_ribosomal_eL19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039547">
        <property type="entry name" value="Ribosomal_eL19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023638">
        <property type="entry name" value="Ribosomal_eL19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000196">
        <property type="entry name" value="Ribosomal_eL19_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015972">
        <property type="entry name" value="Ribosomal_eL19_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033935">
        <property type="entry name" value="Ribosomal_eL19_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057259">
        <property type="entry name" value="Ribosomal_L19e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057260">
        <property type="entry name" value="Ribosomal_L19e_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006343">
        <property type="entry name" value="PRK08570.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01280">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25476">
        <property type="entry name" value="Ribosomal_L19e_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01416">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48140">
        <property type="entry name" value="Ribosomal protein L19 (L19e)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00526">
        <property type="entry name" value="RIBOSOMAL_L19E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL19" evidence="6">
        <location>
            <begin position="5"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="159"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1902069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="190" mass="22027" checksum="B3C6A1EFF504930A" modified="2025-10-08" version="1">MNLVNLTTQKRLAASVLGCGQGKIWLDPNEVTEIGTANSRQSIRKLVSDGLIIRKPVTMHSRSRARELNLSRRDGRHRGFGKRKGTADARLPSQVQWMRRLRVLRRLLVKYRASGKIDKHLYHELYHLSKGNTFKHKRALVEHIHRAKAEKLREKTLKEEMDAKRAKTKAARERKLERQTAKRNALLADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YCL6</accession>
    <name>A0ABR3YCL6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_006881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000402">
        <property type="protein sequence ID" value="KAL1886060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1886060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="110" mass="12424" checksum="B4F9F01EA1AE9625" modified="2025-10-08" version="1">MSSKELTAILMPSVEGLSDEPHVRDEHSINELLNELCHFPLAVAQAADYVAVNQISIAEYLELLREPNEGKVKHMKHNHVDDVHLDNSQGAVATTWLITFWQIQKLDPMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGK7</accession>
    <name>A0ABR3YGK7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mating type 1-1-2 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006612</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000334">
        <property type="protein sequence ID" value="KAL1887279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031472">
        <property type="entry name" value="MAT1-1-2/MatA-2/Smr1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17043">
        <property type="entry name" value="MAT1-1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="382" mass="42912" checksum="B89B2ECACCFD6839" modified="2025-10-08" version="1">MDLAYKDFTLDAVKEVMVIIDLTMYASSQPLVSAVRALASGIKLDHNGIVHRLLHAWNKAAMPFIFDIKLSRGISLQGYRAIVLTTNMWKPMAHLQTAERHAILAANSATVAILAALIIVHWLLSYEIDPASIDGMMEPYGVLGTEVFLRFMWDQVLPPLDILKNFPGRELGLRAGSSIKFDDDLSLHISVKNIYGRVGWKNLPYLHPAYRVYGSSWSKFFRNRGQSMFFKGDYTDAAYWSRPITFAIPTKTLEWISKLKEEYALAARKLGDVPLMSFETVAGLSGEPYPDFSSNKPSVECRYPITDLNGNLTLNFCETLMACDPDGPIDPPQNTDFLAPPFLNRPSEGLMLFKCRKYEMPRQQPITTTSDPWGESVGKSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGX1</accession>
    <name>A0ABR3YGX1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA repair protein rhp55</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_006645</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000340">
        <property type="protein sequence ID" value="KAL1887220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052093">
        <property type="entry name" value="HR_Repair_Mediator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46239:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46239">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 3 RAD51C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="310"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="494"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="326"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="342"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="367"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="398"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="464"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1887220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="533" mass="58450" checksum="C1F9184E7A0A37F7" modified="2025-10-08" version="1">MKQSVDRLPAVSAAEALDDPDDDSLRPISTGLDDLDAVLSPVPDLELQNASPDSNSEAGDLSRGGIPLGQITEVWGPPGVGKTTFGIQTAATALVKKRAVMWVDCNTPLWGPRFADVLNGVYQSQLRAAKPMARQSSEAHEEQSQPEAAEFDINSTDFTYNHCDTLAHVLALLCQGPADKRLQAVQFLVSSLQKLAATRQCAVLLLSQCASKVESGRAASLVPAINGTVWEQAIATRLVLFKDWIWSGRDSEVMPIRHHSFQEVVFVGVQKLQGKTCVYAMEHMVGFRIESAGLVSVKDIRRNIDRPFAERHGPKRNVSEAGLEIPDSDDEEDEYGWDDRYNNQVPRPSQWQGSEDLILDANRHDEDDGEGDDNDAISEPILHDGDHLDAIATGNRSGDGDRTSGTMTRRDGVPECGEHYGEKYGEHRNMLGFQDARRGQQYGDRGQWGSAERDRDEADGGVQSGAQSQGFTSSQRLVLGLDFSTATQGRRLGEAVVTTGSSRARVRAKPKTKAREEKAKADYNVTRRPKRTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHR3</accession>
    <name>A0ABR3YHR3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dolichol phosphate-mannose biosynthesis regulatory protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">dpm2</name>
        <name evidence="8" type="ORF">Cpir12675_006396</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the dolichol-phosphate mannose (DPM) synthase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DPM2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000293">
        <property type="protein sequence ID" value="KAL1887858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009914">
        <property type="entry name" value="DPM2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15039">
        <property type="entry name" value="DOLICHOL PHOSPHATE-MANNOSE BIOSYNTHESIS REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15039:SF11">
        <property type="entry name" value="DOLICHOL PHOSPHATE-MANNOSE BIOSYNTHESIS REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07297">
        <property type="entry name" value="DPM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1887858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="79" mass="8683" checksum="8DE8C83DE325FF01" modified="2025-10-08" version="1">MLVAASVVFLYYTLWTLVMPFVDDDHTLHSLFPPRVWAIRIPVILILVGGAVVGSFVSTVMIRSNQKKALKAAAAKKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI20</accession>
    <name>A0ABR3YI20_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SMODS and SLOG-associating 2TM effector domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_006514</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000313">
        <property type="protein sequence ID" value="KAL1887517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041622">
        <property type="entry name" value="SLATT_fungi"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF033635">
        <property type="entry name" value="SLATT_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38793">
        <property type="entry name" value="SLATT_FUNGAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38793:SF1">
        <property type="entry name" value="SMODS AND SLOG-ASSOCIATING 2TM EFFECTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18142">
        <property type="entry name" value="SLATT_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="SMODS and SLOG-associating 2TM effector" evidence="3">
        <location>
            <begin position="145"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="354" mass="38690" checksum="10E4042A86969F5F" modified="2025-10-08" version="1">MTPSKSRECSCASTPSSSTPLLAPPDSSKRATNCRCPSPNQTADGKRQDCAALKPSSNVVFPQASLQSETYKTTTEVSSSKSLREPTDSGDESHRLLSDCEWRVIAESVGALTNGEDAKLVHANQSLWPPRGMPLGLYRDIVFLRAKYFYLYHAIITIQWAGMVLQLFLGASLTAIGSMSIDDSTTITCLAGANTVIAGILALIHNSGLPNRYHNDRAEFVRVEDHIRKILEGGVVEQNMTTQDIIANCFEMYKKAKEAVFVDSPGYSGSPFGHPTNNTPRYMTFVPRAMAPLTTLPKPIEIQTEVLSHHHNKSPTRLLNTKGTRTIGPSPDAGPTPTQHAREDKRVREAALLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YIZ7</accession>
    <name>A0ABR3YIZ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000268">
        <property type="protein sequence ID" value="KAL1888294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040976">
        <property type="entry name" value="Pkinase_fungal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248:SF2">
        <property type="entry name" value="FUNK1 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248">
        <property type="entry name" value="FUNK1 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17667">
        <property type="entry name" value="Pkinase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal-type protein kinase" evidence="1">
        <location>
            <begin position="262"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="734" mass="83797" checksum="61202D0AA5780AD5" modified="2025-10-08" version="1">MELNPRSLIIHAYPIGACLDPFYNVLIEGCAKAGIEPTADAFDQLDQVELGAHLAYSLTGASAARCFPSNYHKGHSFQTDLYDLRHNVYHPQFDRQRLKPLFSAVVAHIRNDFHVWDEADKVVEYSIYICGGKIKAYDLRANLGLELNTLYVDVPDLFSTILTGINGLETVSTSFFEKCTRDCNPRFQAEVGWTSWPTTMTKSNLMRWLTEFTDQLANHIDDMGSIPGLKKKLVVEPANNIENIIRFLKTNVCFTYCRDDVHSYYQTSRFLVVGTLRCDPNADSSLVTWTELVSSVKEVFFTQYFRRFALGFTLCGSIMRIWLFDRTGGVASQSFDINKDGKQFVDIMAAFLLMDSEQLGLDPTLMQSDSQVFIDINRNGVSERIVIDQTLYDNKCIAGCATKCWRGHLEGHPEMTLVIKDSWRSSKRHDVGQMLRKLTERGIPYVARYYHHEAVHLNGFADSTQDNVRKGLDVSKSKSRHLNQNLMSESDKYHGLENIHPEMLSEDGLLSSKTTNRIHHRLIMRDDGKRIHEAESPSILLNALVKCIRGHEELFKAGILHRNISLSNLIVAQDGDSSSWPAFIIDFETAIEVDKASNSERNVGTKPFMAVGVLLGQEHTFMHDLESFFWVLFWICIHVTGPGKYELSKEQYHSWFEMRMSRIAMSKVQVIANDQMFLHAANQDFSAYLRPLVPWVNKLRILLFPEGASDKREDLNVYNQMCSVLEEAAFSFRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ63</accession>
    <name>A0ABR3YJ63_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_006211</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the major facilitator superfamily. DHA1 family. Polyamines/proton antiporter (TC 2.A.1.2.16) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000265">
        <property type="protein sequence ID" value="KAL1888355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF186">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="243"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="322"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="400"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="425"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="456"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="493"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="91"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="542"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="580"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="594"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1888355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="617" mass="66613" checksum="22275F0CA2A41FC8" modified="2025-10-08" version="1">MTESSSSTINASAEAGTGSNHHHRHDLENQKPHVPRYSHWNVLLKPHGVSDAVLQQKYPGNGTAESPFVIDWLPVDPHNPQQFSHMRKWAITLLVALATFAVAFDSAAYSGGVRQVIAKFGVSQEVAILGVSLFVLGFAIGPMLWAPLSELYGRQVVFLGTNFCLTAFLGGSIASQNMATLVILRCLAGCFGASTMTNSGGVIADMFSAEERGSATAVFALAPFMGPSLGPIVGGFLGQSSGFRWLEALMCIFTGIVWVMVVLMVPETYSPVLLRKRATKLTQLTGKIYISKLDIIRPRKSVTEEFKVALVRPWALIFREPIVSLTSVYIAIIYGTLYMLFAAYPIVFQVHRGWSQGIGGLPFLGVLIGMMSGAMYYLWDNRRYMAIVNARGVARPEDRLPPAIIGSFLIPIGMFWFAWTNSPSIHWISCVMGGGVFATGLVLVFLSMLNYLVDSYVIYAASVLAANSVLRSLFGTAFPLFTTYMYDDLGIHWASSIPGFLAFACLPCPLLFYKYGESIRLKCKFAAEADAFLKKIMGSGGGSGGDSSEESSSGQAAVGRGAVDSMGGDAADEKLDGRHPSQNSATGTPSLPRKLPDRNDLSEKALERHGNGPSTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJV8</accession>
    <name>A0ABR3YJV8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Amino-acid permease inda1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">INDA1</name>
        <name evidence="10" type="ORF">Cpir12675_006155</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000259">
        <property type="protein sequence ID" value="KAL1888497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF12">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="362"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="404"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="432"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="476"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="511"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="9">
        <location>
            <begin position="75"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1888497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="573" mass="62560" checksum="95450A35F8CA946C" modified="2025-10-08" version="1">MAHDNDGFPAKTADPEKTPAYANDTSSASAVPAPTYGRYSEGFWTRNGLTPESFRRRIVADGEAPELDRTLKKRHLHMIAIGGSIGAGFFVGSGAALAKGGPGSLLVDFAIIGVMIFNVVFALGELAVMYPVSGGFYTYSNRFINPSWGFAMGWNYVLQWAVVLPFELVTASITIGYWDREGSISRGVWITVFMLVIIIINIFGTLGYAEEEFISSFLKLTATVVFMFMAIVFVCGGGPSHGRYNEYWGTRYWSDPGAFQNGFLGFCSVFVTAAFAYSGTELVGLAAAEAKNPVKELPGAIKQVFWRISLFYILGLLFIGLLISSEDPNLLDTSKSGSDTSPFVLVAEYAGLPGFAHFMNGIILVSVISIGVSGVYGGSRTLVALSEQGYAPKIFTYVDRAGRPLLAVGFVIGCAPIAYVNLSSAGNSIFDWLLAISGLAALFTWSSICLAHIRFRLAWTKQGRSLDMIPFKAAGGIYGSALGLCLNILVLIACFYVAINDLDAETFFKNYLAAPVVIVFWLGAFIWKRSPWVSLENLDLDTGMRQHNWEEINDFRAKIAALPKWRRILHKVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJW7</accession>
    <name>A0ABR3YJW7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SUR7/PalI family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006237</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000269">
        <property type="protein sequence ID" value="KAL1888255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052413">
        <property type="entry name" value="SUR7_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28019">
        <property type="entry name" value="CELL MEMBRANE PROTEIN YLR413W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28019:SF7">
        <property type="entry name" value="SUR7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="340" mass="37139" checksum="4009F1B5EC1D614A" modified="2025-10-08" version="1">MYKYSEPKVVGGRFHLIYLLPFFACMAVFIMSMVCALAGTNKGVLEEMAVIRINTSRLGYFLVPSNSSDSDSDQKDSEDNSILDDIIDSASDIADDAKDKLSEIGNDIVDKLADELGISQWYSLHLVSACQGNFSSGGLKTDNCTEARANFRFNLTNEIDKQLSVGPLNLSLADIGFSTSLANGVARQINHLLPFVFLVFMLYMTGSIMACFTMALSGALVFLDPNGLTQNRRAIVFRTALVCSAASTVSLGSGLFVTWFTTSQVAQVLTDFGDTIGLSASSGKLFLRMSLSCVIMIGGVCLLLVLEQYKPKMLEAKDIMRSKISRKNGQGQEYLRKEYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKA1</accession>
    <name>A0ABR3YKA1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RED-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_006255</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000272">
        <property type="protein sequence ID" value="KAL1888206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039896">
        <property type="entry name" value="Red-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012916">
        <property type="entry name" value="RED_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12765">
        <property type="entry name" value="RED PROTEIN IK FACTOR CYTOKINE IK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07808">
        <property type="entry name" value="RED_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RED-like N-terminal" evidence="5">
        <location>
            <begin position="58"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="143"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="270"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="424"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="24"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="283"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="369"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="481"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="516"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="536"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1888206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="547" mass="59616" checksum="9506CB112789A0CE" modified="2025-10-08" version="1">MNNNQFRNLVVASTQKAAAETADSHSSSPPIQQTSSTHGLALKYNPQASERMRQAQHQKLFKSAAPKGVKLATGYTDRTKNRHDDDERVAEIQELERQLKEKEIDRATYERRRDEITSGDVHATHLVKGLDFQLLKRVRQGEDVFGSSETKPTANIAGQDEASGSREADSIDDALDDVLGNELKAVAHEKTAKKGQLSTVTTAPGQKRTRNQILADLKAARAAAKTQQAEGNAVGQRFKKIGAKQTPGSRIEIDRNGNEVLIIIDEDGHEKRKVRKAPVPAAGTTSATTEGQNNEDILGHMMPDPNAAPLGMEVPEAYQSRKEQEGEDGDVNIFDDAVSDYNPLAGLDSGSDSDSDEEKDAKSEAKSLPSNDSEQNQVSLSSTAGPKNYFKDSKGVLASEQSLQGPSWSDPALQAVLKKAATLKPLATNNSDDEDEDSHDPEAAARKEKRRKMLQQDDRDAQDMDMGFGTSRFEDEEEADESTKIRLSRWTDDLAGGDGDGDGDDVAGQEREGKTQRKQGGKKRKSNGNSAADIMRIVEQRRAAGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKK5</accession>
    <name>A0ABR3YKK5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Histone chaperone RTT106/FACT complex subunit SPT16-like middle domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_006073</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing. Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA. Plays a role in the transcriptional regulation of the cell-cycle dependent histone genes by creating a repressive structure at the core histone gene promoter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Interacts with histones H3 and H4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RTT106 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000249">
        <property type="protein sequence ID" value="KAL1888708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013719">
        <property type="entry name" value="RTT106/SPT16-like_middle_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050454">
        <property type="entry name" value="RTT106/SSRP1_HistChap/FACT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45849">
        <property type="entry name" value="FACT COMPLEX SUBUNIT SSRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45849:SF3">
        <property type="entry name" value="HISTONE CHAPERONE RTT106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08512">
        <property type="entry name" value="Rttp106-like_middle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01287">
        <property type="entry name" value="Rtt106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histone chaperone RTT106/FACT complex subunit SPT16-like middle" evidence="5">
        <location>
            <begin position="236"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="387"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="396"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00037550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1888708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="479" mass="53145" checksum="48B3C8FDAA33EF0E" modified="2025-10-08" version="1">MASPSLDSRTLSLVFQAKPDIVTRIQRAADTPDHISLFNDIANFFYDQLHSSDEPSSKRRKTETPSTPNGIVSVTSEPVQLEIKEISLSVPVRKKLDLCFTSSGLYGRASGSKEAVPGTVFSWSDIEFAFYLPVPEKTQVQHNYVLLPRGSSFITKATPTPDPLVFTVNATPPKAGTISGPKAAAAQPVSGDYNSLFDWSFSTFLRSAGSNVQIVASNPARFHSMVKQSHRPNEKAVHIKAFRGSKDGYLFFLQTGILWGFKKPLLYIPLERVAAISYTSVLQRTFNMVVEVFSGEGDNTEEIEFSMIDQQDYQGIDELYVKKNGLQDRSMAEQRKAKLELAENAKAVKNDGGDDGSEDVEMTQADEDATVAMNPALKHMTALERAEWEEEQRLQDEEDEEEEDYNPESGDDSDGSGESNDEDSDDMDSDANDDDDDDDDDEEGDEEGDGDEDEKEQQNQQQQQKQPTTRVGGWAALNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLJ1</accession>
    <name>A0ABR3YLJ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Meiosis-specific APC/C activator protein AMA1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_005962</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000235">
        <property type="protein sequence ID" value="KAL1888989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033010">
        <property type="entry name" value="Cdc20/Fizzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918">
        <property type="entry name" value="CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918:SF5">
        <property type="entry name" value="MEIOSIS-SPECIFIC APC_C ACTIVATOR PROTEIN AMA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="504"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="42"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="310"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1888989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="691" mass="76585" checksum="F351C3C0891EE64E" modified="2025-10-08" version="1">MPSGARKRRRADTHVTRSYSSDDNFGWKENAPSPILPPLLCSRNLSSRTRSTRSWTDSQTSSQTSPPPTSITAATATPLAPISNQTHETHGERLTEISKARLPSSSIPVIFFSPTIVKRNRRVASRQNLDRFITHRKLDSSLADRFQTTKSSLELTLYESLARSNVASVDPFISTPQQRNFALSQRSQALARNHERQLHQRSQRMGSGSIWNIGGAIPPINDGRGHLIQSGTSATRMYVTSWPGPDPGAIEESDMYSSRIAAALGLDRTERIFPIGNPDITEAEEGRRSDPRSIARNISSSTKWNGSRWVNDKTRPEKRNNSRTIPTAPFRVLDAPNLRNDFYCSLLSWCDTSQILAMGLGGKIYGWSENADIILLKDSGKNDEFEPWISALNFSSAEGRKSILAYSTSDGELGLIGIDDFRQKETQPRFSQRFEGRVSCLSWRPKVTWRPSLNPLLRRALVPNEDLLVGDERGCVSYYAVEWPSGTIERGVGFHGSVTLLARVFIHSQQVCGLAWSPDGSMFASGGNDNVCSLFEADHFLASRMDKLSVTPTAISRLSYLLNSHHTYIEDEPIDTLIPPIAEPLQTAEHQTRLPKHTWVHSAAVKAIAFCPWRPSVIATGGGSTDKCIHFFHTTSGTALATIAVSAQVTSLIWSTARREIVATFGFALPEHGRRIAVFSWPDCREVAALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLS1</accession>
    <name>A0ABR3YLS1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DOMON domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_006027</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000242">
        <property type="protein sequence ID" value="KAL1888852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09630">
        <property type="entry name" value="CDH_like_cytochrome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015920">
        <property type="entry name" value="Cellobiose_DH-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05805)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797:SF4">
        <property type="entry name" value="DOMON DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16010">
        <property type="entry name" value="CDH-cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00664">
        <property type="entry name" value="DoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
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    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
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    <feature type="chain" id="PRO_5047168810" description="DOMON domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="404"/>
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        <location>
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            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="285"/>
            <end position="303"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="349"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="DOMON" evidence="3">
        <location>
            <begin position="60"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="404" mass="42705" checksum="587F859AD3D97B76" modified="2025-10-08" version="1">MRVASSLAMAATLLSPAAAIYSSCFDSNGFCVQIGVPEATISSSSGNLYMQMQASTSYSWVSLGQGHGMAGANMFLMYTDGAGNVTVSMRYATGEVEPYAQTDSKITILEGTGISNNVMTANFVCENCDTWGTGSMDLGSSETEWMSAWKTGAPLDSTSQDASIQVHDNTGEFPVDLTAAVIASDSNPFVAANSNSNGTVLVSSTGGGDSGGGDNKDLLKIHGWIMASMFVMLYPLGTVVMPALHQWAIHGIIQILAMIGMWIGYGYGHAAANKVDSLFDDCHQMIGAVVCAGLTVQPITGWLHHRYFVAHKTRGAISYGHIWYGRLLLGLGIVNGGLGISSANSSTKVVVAYAVLAGFWAVVFAVFSSISDYKKDRMRMKSGSDKGIALNNYQAMGSSEDQRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMV4</accession>
    <name>A0ABR3YMV4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_005694</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000208">
        <property type="protein sequence ID" value="KAL1889690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF132">
        <property type="entry name" value="PROTEIN-LYSINE METHYLTRANSFERASE C42C1.13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1889690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="404" mass="44383" checksum="7FE95D73C1F08496" modified="2025-10-08" version="1">MHYIRFVRPPTVTIRDQGKTVLRLALTIATDLGDAYLCPEAPILLTLTYWVNGHLQKPPLPLLKWTAGMRVCKLDVPLKVLARGSFVTKIFVSPAEPNLGLMQMQQLLTQKTPMIVPVVATPALPGVEPKLFTNRQVLLGDVQNKRMFLAISEEIQDSIARRVWDSGMVTAALLFELAAHNARPSKLLPLTQDLVRADALNVLELGCGVGTLGISMATALAQRHITPAPAEADVEHAEAITEARSSPKISRHRIVLTDLPDAEEVAQQNIELFNTAMSGLVAPAVAYENLDWFDCKEGVFGPLVSSSQNWDLVIISDCTYNADVIPVLVSSLDKLHSIALQKSGKGPHILLSTKFRHDSETVFWDQMKMAGWEVREKVEFPVANIGAAAEQIEVYLFSKKAGTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNM1</accession>
    <name>A0ABR3YNM1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_005754</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000214">
        <property type="protein sequence ID" value="KAL1889514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15534">
        <property type="entry name" value="PHD2_PHF12_Rco1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052819">
        <property type="entry name" value="Chromatin_regulatory_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
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    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
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        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47636">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATORY PROTEIN RCO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47636:SF1">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATORY PROTEIN RCO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="1040"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="7">
        <location>
            <begin position="1337"/>
            <end position="1574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="80"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="163"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="415"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="609"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="736"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="820"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="876"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1370"/>
            <end position="1400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1490"/>
            <end position="1530"/>
        </location>
    </feature>
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        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="109"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="240"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="502"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="512"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="542"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="611"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="632"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="680"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="758"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="824"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="876"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="901"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="926"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1000"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1388"/>
            <end position="1400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1512"/>
            <end position="1521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1889514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1574" mass="166797" checksum="47F65B153F9F9A6D" modified="2025-10-08" version="1">MSTRATRSRIASPAQAQGQGMNSSTNIQSETTPKGAASSGDSSRSFLQRWLEPEIQNKASFEEHGLMRCGVLENMAALGTLPKLPPKKRAQQNSKSATPMATPAIGSRASMTTAGSTLPDRQSDKQPVRKIILHPPASASKSKRTTDIDYAADGNIGANVEIMASNSSASKPGGRKTTSKDFAPPEDENDDDYRPTVKKPRPGASASGNDNSSASSNANSATTTSIPRRHAASASASAANPGQLSLSVSTEPKPGLGKDSSATLTATDLIMTTPTPTGRKKRAAASVAAAAAAKSASLEAAAETVKALVHKAESQGRHATARTLQAAYNENAGDAEFLSVIDKIYRQRSRQSDTSMWAQYERLIGEKRRERRENYSALGDGYDDNDYIESDDDDYNSEVTATAIVGGVQIQRTMHRGVPGSDCNSPVGTHGHGALGFGESVSDSATSAGAQAKSARKRRAGVSRDVRNSGSSGFELGSGSGSTVADHSSLGLDQFQPGWGPRSSTATSARTCSISGPNASKTTITTAANSSGSKKKKSAMRNSSISNNSNNTTITNTITTTISSRKPETSVMLGEPQRHHSSHGRENSDQASSQSQLTPFTRVIKLKSRVSLPSSASPRTPASAKAEKEIADSADEEEDGGDDVSPSSPCTASRNVAADRASSSDPSKAFANVRSSKPRSLSLSSDSSLSSLSSVDENLLLSEDENTAALQRDHGHNYNEQRPQGQPMMTKNAKLVSSANHRGGIKGTKSRVNKSKGTTTATATNSTSINLSAGSNSAKHRSSSASTLSLSSSQPTTISDFFRRTAQLHQEYKAKLDASSCTAPLNPSSHSSSPLVTSPSQHHASLVEEAEKAKLDSVAELRRACIENTTVLTPNTSSSIREATSQAHEASSFRLRPLPPQINQSAPTPTSIEAIDDTMSNKRRTAPAPGTASTSSTSSLSSMSSTALSLSIPSASGARATRSSLKRPHEGDDAALEASPPRPVSHTPSRAVTPSLPPSKKQRMGPRVKLSPKKGSATFAGAPRPSSRSGNDSGLSQDNDDFCSACGASGELLCCDNCVKSFHFGCIDVESDKLPDQWFCWECRITRVPSTLQLSPVRGCFAALEVVLERNNPRAFQLPHHIQTLFEGVKVAADGTYEDVLPLTKKRDRKTEDFTDWYKLRDGDSIVLCKACHKSADTIRPIIPCSKCGLHWHLDCLDEPLTVPPVLKTWNCPLHVEPDALAMLISGPAHRYRRIKNVPVIPPMFARGNHNNGILEIEDDLDGLQNEYEQNLQQSRNAGWADPQSFGRTYRLKASAVVKDFIESVTISKRPGTLAEKLLKTIWLEKKLEKKKADEGRSLFQDCSIPEAEAALVIATMAHAPDLTVAHASPATPTLKSTEPLAIPASPAPTNSSKTDSDYNPSLASLNSSASAATASMAKEDVLSLIARQSTNLIAGGGPLSESTKSFLRGAVLQIQLALGDDAPTPPLDPTKSLPPSPIHAHSHVVRFESALSSSQDPMQADGSDSMMTDLPRSEAGREPTEPATASPEVRVQVHARKAGDDGSFCGTANRQRSGVVIVDDEAMSDDVTAIPEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YNX5</accession>
    <name>A0ABR3YNX5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7053 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005689</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000208">
        <property type="protein sequence ID" value="KAL1889685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055481">
        <property type="entry name" value="DUF7053"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38117">
        <property type="entry name" value="NACHT AND WD40 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38117:SF2">
        <property type="entry name" value="NACHT AND WD40 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23155">
        <property type="entry name" value="DUF7053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7053" evidence="2">
        <location>
            <begin position="6"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="361" mass="40249" checksum="95B6ECF73067AE9D" modified="2025-10-08" version="1">MSRFMQKKDSFTIITPIPSFIPRQLALDIIHSHSEIITLNPLVLSHTPIAAPRNAAADEYYSTWYEITERIQYVPGMGALGSGKISFKGCFHDTTWGLQTHIYAPMGIDLHNTYRIAGNEPGERPEPAELGLLSLGAPRDGLYLREDIVIRCNITLMSFVRGQMKAASKQVVQRFIKKAELLDAGALQAMFENGRLRTLNPKDLSDVAAQANIARGQTTSYPRPESMTPRSASMSPRPESMLLRQANMSPHPTIMSLGSTNATAMQMPPPYQIPVEMPGDFTYRTFSSQAEDQAEQRVEFPHGTLNERSFSARLSQATRLSPALPPMPLALQESKYQPEMVEIRRSSHMENGTLCLDADQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP10</accession>
    <name>A0ABR3YP10_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">cAMP-dependent protein kinase regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_005542</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8 9">Tetramer, composed of 2 regulatory (R) and 2 catalytic (C) subunits. In the presence of cAMP it dissociates into 2 active monomeric C subunits and an R dimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the cAMP-dependent kinase regulatory chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000195">
        <property type="protein sequence ID" value="KAL1890091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd12098">
        <property type="entry name" value="DD_R_ScPKA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050503">
        <property type="entry name" value="cAMP-dep_PK_reg_su-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012198">
        <property type="entry name" value="cAMP_dep_PK_reg_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003117">
        <property type="entry name" value="cAMP_dep_PK_reg_su_I/II_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635:SF152">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE TYPE I REGULATORY SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02197">
        <property type="entry name" value="RIIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000548">
        <property type="entry name" value="PK_regulatory"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00103">
        <property type="entry name" value="CAMPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00394">
        <property type="entry name" value="RIIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0114">cAMP</keyword>
    <keyword evidence="4 9" id="KW-0116">cAMP-binding</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="11">
        <location>
            <begin position="237"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="11">
        <location>
            <begin position="369"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="197"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1890091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="495" mass="54051" checksum="3762388A257A023F" modified="2025-10-08" version="1">MHTAKPALNAPNYTTQAQARYSSKLDPPTMILPDAYRREIQALENQFWASNPTDVVQFCADFFTARLAAERASIRSISARNSPRSGTPDITSESFDSFASYKMSNTFSNPFATGANPFDSTPKFEPSSYGSSNDNAMQLIEEEASDDIRAPPASSIRSLGASGAFRSPFAAFDGPDSSNLHKGSGLPSQYNLGRRTSVSAESLKPSTGSEDNWSPPFHKKTPEQLERLKKSIQDNFLFSHLDDEQSNQILGALVEKPIPAKDIKVISQGDAGDFFYVVEKGNFAVYVNSTGSLQPGMDGMGTKVNEIGPGGSFGELALMYNAPRAATIVSVESGCLLWALDRITFRRILMESTFSKRRMYETFLGEVPLLSSLTPYERSKIADALEQERFSAGQSIITEGDFGQTFYIVESGEADALKGDTIVKNYKKGEFFGELALLNDAPRAATVVARTNTKVVSLGKSAFQRLLGPVEGIMRRTQYVGIASGVEEMDPLQKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP73</accession>
    <name>A0ABR3YP73_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Polyadenylate-binding protein-interacting protein 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_005684</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000208">
        <property type="protein sequence ID" value="KAL1889680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013899">
        <property type="entry name" value="DUF1771"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002625">
        <property type="entry name" value="Smr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036063">
        <property type="entry name" value="Smr_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045124">
        <property type="entry name" value="Su(sable)-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13119:SF12">
        <property type="entry name" value="PROTEIN SUPPRESSOR OF SABLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13119">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08590">
        <property type="entry name" value="DUF1771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14608">
        <property type="entry name" value="zf-CCCH_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01162">
        <property type="entry name" value="DUF1771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00463">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160443">
        <property type="entry name" value="SMR domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50828">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="276"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="306"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="Smr" evidence="8">
        <location>
            <begin position="586"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="276"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="306"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="334"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="337"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1889680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="722" mass="78965" checksum="985ECE19B20E013D" modified="2025-10-08" version="1">MVSDEHYEQCLPILRDPELQDEDKTDKIEELFRRETSLDGSALENAILDVLWRHREGSASTSPPPIRHTILRRPSPASWRGNSTPLCESPRLGVSPLALPSYISTSFPRSARSVNVSPFSSPRPSPRLAFSTPGIPNSPSLNAYEFANDSAPSTETFNEYQTENVEWLVADDAVSLSSSVGTTNSLLNASAPEFSSLASQQNNMTPYDMLRSILGQSRTDEEIESALASHGYDLSATVVSIMESQASAVDSSDEPRTVLVGRAINSEHRPSTPNNQKSGVICKFFLSTGQCLRADCRFSHDLSNHLCKYWVVGNCLAGDTCIFSHDPAQLMSRLTLDGNNTPPTAANTKGQGGSITVQDFSSFPSLQPGTPDSMASGNGYRRSFTPPASLRHIHGSDSPRNRSRPGSRHQQPKEQAPALDDTEAFPSLGASVKQSKKPINKRPGNKDGYTPSLLADVVKMAPSPAPSPRPENKTQARIAVQGSRENSAAAQAIAAPRHIPWLETGDRANKAYLKARQEAIKHGGLRNKFLQSAAQAWNRNDARAAKALSLRGQSENELMKKAHREAARELYEERNKSLTMSSEIYVDLHGLHADEAVRYLEDILLESINESRPIYAITGTGHHSKNGKDKVGKAIRAFLNEWRYAFREFSVPGDRNNMGGILGIDARSWDKTLSRKNAPSVFDRAKSQSDLLSQGVEIGEGNVRMLVRAESPRGPTKATKCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPY1</accession>
    <name>A0ABR3YPY1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_005405</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000184">
        <property type="protein sequence ID" value="KAL1890391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051654">
        <property type="entry name" value="Meroterpenoid_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35897">
        <property type="entry name" value="METHYLTRANSFERASE AUSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35897:SF1">
        <property type="entry name" value="METHYLTRANSFERASE AUSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="227"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="265"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1890391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="379" mass="42773" checksum="4CA261CABFE82CD1" modified="2025-10-08" version="1">MDIFDMYRLIYQEDLPHDIAPMTGLLQRYSHLPSDQIESHLHSIRDKAWSSIRTPCIGRWRFLYGMPASDPCYKLAVQRLKSAFSRDCLLDLGCGMGQALRQLADDGVPISRLLGTDVHPSMIDIGFDLFLDRADEPTSVLSPLARIFSRRRLGLGSRFVVADLLDDCDSGLKLLSGHFSIIHASNFWHMFTWYQQIEIAVRLVTMLKPGTQNALIYGRHIGRKEADPVPDFHSGDNGHMNSRNSSNNDDHRLNDPYEFSLSHDNSFDEHDHHGPSPRSPSISSISSISSTSSFDSEVAPFSDTSSLASSVSFSLPSETDDKRAFLHDQKSFQLLWDIVGGRTLTRWRVEVDFQSKTMADLPGFGEDVYVVHYGVHQIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQA6</accession>
    <name>A0ABR3YQA6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005372</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000182">
        <property type="protein sequence ID" value="KAL1890478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17716">
        <property type="entry name" value="BRCT_microcephalin_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022047">
        <property type="entry name" value="Microcephalin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14625">
        <property type="entry name" value="MICROCEPHALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14625:SF3">
        <property type="entry name" value="MICROCEPHALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="1118"/>
            <end position="1222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="456"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="594"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="805"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="978"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1226"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1352"/>
            <end position="1373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="110"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="511"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="679"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="833"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="845"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="862"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="889"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="978"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1010"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1035"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1098"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1265"/>
            <end position="1277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1416" mass="151680" checksum="B194C917EEB5AC09" modified="2025-10-08" version="1">MPASRITRATAASSAKSGTAASRARVSAASASASGSSATTVPKPPSLSTATKRKTRTYEAEGDDDGSNNVNGQGTLAAGPSRPLRNPVARPTTRARSTMKKSADEPPSRAVPTRTAPASRATRTTAASAARATRTTTAAAARAAPKASVRETLAQTRSRAGSTVTATASDSSSMVGGPTKKPRISAPTGTRMAAAAAAAKKTVSFAAGAKPEKENIAPASNTVAKPGGIRGRPMRKAASGPAPASSTMATRSRKTAAPESTGDKPPLGSVSMPTPANASIGGAVDEDELTAEPLAPLRQSPKKKGRTGVPESTTLFDLDTTASHGFSNAVSADFNATETGQIMLTSPAKRIPQPPVSPQETMRSPAKRGPAENMFIGGVMPKPGQTASSDLAAEKSTLLASPAKRPQSPIKGFGAGLSSHVESQKQGQKASLLMSPAKRPSSAFKVLTRSFDLSQAVPSLPTMPGSPNTADSTTEHAEDKGPAMKPSQLLMAGEETTSDPFHSRGLLFRQAPPSLKLPSRKPSPSASKEDLTGDMFAPVRRSLSNGNQTQTDTEVDSENSADKDGGVDYNHQENCLEFDDEDSIALFDDEATGTLTLTDAQVQIREDVEMMSPRRSWPATFKMQAESGNENSEGDLADNSNHSGDGAPLSGFQMEEGQEKYHEEEGTMQSEDVSAANVKKASTPKATPKTTAKATPRPTPRPTRQRTSRATPKATPKSTSPVKTSAAFGLRSQDVDPYATVDNDSGDDDISRLPHPYNNAPETPDISHQAKPSRTPGTVKGCISNTSDGFTPLVNRLDAWTPAAPIVHSSDASEDEANGEHDENIEYEEDGEHEVKTPYDHDHDEFDDDDMEMEDDNVPGTPRSTHSASNVSYAHMTPSFTERQHGDDADIDAQFDTTSENEPERDGSEEERDDDVSMLDEDGFDDVDITEEDIALAIEAQEMSLLGPGDIEELNRSYEELEDEAARYYLQYEGAAQEYEEEADNVGENMEEDVEDDIDHTEHSGPLAESKVHDDANDHHEEATPIPPVTPARYITKEFHTVSKVPLKDADEPSPSPSDRGTRLRASRPSIQRHSIGHAPESPARNTDTIEAPPITPARSQSSWSNAATPIQTPGNRLNDNALHGATIFVDVFTADGADASAIFVELLTQMGAKCVSEWAWDPQNPSQMGKIGITHVVFKDGSQSTLDKVRETQGLVHCVGVSWVLDCERDNTWVEEPPYYIYSGSTPRSARRKTTGMLGSPTTPIRTGTRRRSSRRQSTVWERTPTDSDKGVRDDTDGSTWQLSPVPVTPAPEAISRYVATLAPETPSPNDRNENYGMYGVESTTPTDPVNEDNNTPLDEDRMAMLQRTCPPPKRRAVSGKAGSSKKPAVSWVVTPEKEEPKNIMMRLLAARRKSLQFAPKVGSPLSKQWKQREN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQQ9</accession>
    <name>A0ABR3YQQ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosducin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_005481</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosducin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000189">
        <property type="protein sequence ID" value="KAL1890262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02987">
        <property type="entry name" value="Phd_like_Phd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001200">
        <property type="entry name" value="Phosducin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051499">
        <property type="entry name" value="Phosducin-like_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024253">
        <property type="entry name" value="Phosducin_thioredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46052">
        <property type="entry name" value="PHOSDUCIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46052:SF1">
        <property type="entry name" value="PHOSDUCIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02114">
        <property type="entry name" value="Phosducin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosducin" evidence="3">
        <location>
            <begin position="77"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="115"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="127"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="311" mass="34046" checksum="161C3A7C92B34BB4" modified="2025-10-08" version="1">MSDPTPAQEEFNRLVSNSSKNLDHRHPEDRSASPSHSNDLSEEEAFRASQVEDNMRYTHHASASTGAMRLPPASFDANAATGVKGVIADARAYQAAKQSKFKSAMRSARHSIFGGDATLGTTSTCTSGHVRSSSRSASNKGSRSSSRSSAAADLSGSEWADEDAFLAQWRESRRRELEADGKAVRTRRTSPSVRIYGRFDEVDALGYLDAIEKVARDTTVVVFVYDPGCEVSTEVERALIPLVAAHSTTRFVKVHYEEVEFDAAAVPAILAYRNQGDLVANLTGMIEMMPDSESFTSMTLQQLFMQHNVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRX7</accession>
    <name>A0ABR3YRX7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="1">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_005122</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000163">
        <property type="protein sequence ID" value="KAL1891114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08598">
        <property type="entry name" value="PI-PLC1c_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF169">
        <property type="entry name" value="PHOSPHOINOSITIDE PHOSPHOLIPASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00387">
        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PI-PLC Y-box" evidence="3">
        <location>
            <begin position="311"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="15"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="273"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="289"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="589" mass="65189" checksum="DB4A2EA0DE573A88" modified="2025-10-08" version="1">MAFLAASLDKMNLMGRKKRRSKEEDADDVGDEIDGNTVAGGGHLARHSALHRAELRISSAVQQFLVDRGELESTDISTGAEGGPSSPALKALLQKPHFKVPIELLSQSHSLSEYFVSSSHNTYLMAHQLYGTSSATAYETALTAGSRCVEIDAWDNDEDKDEPKVTHGYTLVSHISLRAVCEAIRDVMNKEAQLAESDPAFQTSPVLISLENHCSAHGQRRIVEIMNEVFGERLLGRALDHGDYCDSPESHVPLSLLGHRVLVVVEYHVPNERVDSDSSSSSSDDEEEKAAHKEYHQRKNQEHESKIIPELEELGVYAQSVKPSDISWFDPGELLNGPHHHLINISETGLSAHIPHSSAQIARHNAKHLMRVFPKGTRISSRNLAPVKYWALGAQICALNWQTFNAGMQLNEALFTGTDGFVLKPAALRAGGSGEVLTGRKKRLRLHIAGASEIAPPKGYGEGEDGGGDWKPYVTCTLVHPGKTFGPIKRKTNCYRQHKLGFLHKGENLPATDPMWDETLEWEYEDSELVFLRILVKADLSFSINPNLRVIAVRLHYIVPGWTFLHLTDFSGHPTNSTLLVRFGTEDIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS16</accession>
    <name>A0ABR3YS16_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005114</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000163">
        <property type="protein sequence ID" value="KAL1891106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17242">
        <property type="entry name" value="DUF5315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="183" mass="20012" checksum="3A7675F18C14F960" modified="2025-10-08" version="1">MPSALERDRSDALWAEMQDTLEEVELSASGSAHVFGHDHDKRLAQLRAEQIALAQAWARSEADDAIDVKKSKDVKTPTSGLAENARDADGGGKSIGSSAQRPSTSRVTNEQLGAKLQEETEVDMMLARKRREANDIYFDRVNKGVLDVVAKLGDVATAMSVVEWESRSIWNDGGSVQESNKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS25</accession>
    <name>A0ABR3YS25_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Prephenate dehydrogenase [NADP(+)]</fullName>
            <shortName evidence="2">PRDH</shortName>
            <ecNumber evidence="2">1.3.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TYR1</name>
        <name evidence="4" type="ORF">Cpir12675_005272</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 2">
            <text>prephenate + NADP(+) = 3-(4-hydroxyphenyl)pyruvate + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21640"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="ChEBI" id="CHEBI:36242"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.3.1.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-tyrosine biosynthesis; (4-hydroxyphenyl)pyruvate from prephenate (NADP(+) route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prephenate/arogenate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.13" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000175">
        <property type="protein sequence ID" value="KAL1890692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004665">
        <property type="term" value="F:prephenate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3660.10">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050812">
        <property type="entry name" value="Preph/Arog_dehydrog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003099">
        <property type="entry name" value="Prephen_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012385">
        <property type="entry name" value="Prephenate_DH_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21363">
        <property type="entry name" value="PREPHENATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21363:SF0">
        <property type="entry name" value="PREPHENATE DEHYDROGENASE [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036510">
        <property type="entry name" value="PDH_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51176">
        <property type="entry name" value="PDH_ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="1 2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0827">Tyrosine biosynthesis</keyword>
    <feature type="domain" description="Prephenate/arogenate dehydrogenase" evidence="3">
        <location>
            <begin position="12"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR036510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="442" mass="49494" checksum="D3744EA651A12A49" modified="2025-10-08" version="1">MANENTMKAVGFTVGLIGMGDMGKIYAHHLSSAGWRIMACDREEKYEDLKEEFAGTKIEICRNGHLVSRASDYIIYSVEAAVIGNVIAQYGPSTKMGAIVGGQTSCKDPEVRAFEASIPADVDIVSCHSLHGPKVSPQGMPLVIIKHRASDESVRKVETVLSCLKSKHVYLSAREHDRITADTQAVTHVAFLSMGKAWHAEREFPWVSARYVGGIENVKINIMLRIYSAKWHVYAGLAILNPEARKQITQYASSVTDIYKLMVVGDLLALQERIYAAKDRVFGPVGAPKWARKPLLRSDLLEQFTLRDADAGMDSESPRPNNHLSLLAMVDCWAKLGIVPYDHMLCSTPLFRIWLGVVEHLFCSQELLDNTLRTAVNDHTYRSDDLEFTFAARGWAECVNSGHFDMWRERFVSTQKFFEPRFTEATAVGNRMMTAIVTQDDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSF6</accession>
    <name>A0ABR3YSF6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein RCR2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005454</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000187">
        <property type="protein sequence ID" value="KAL1890284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020999">
        <property type="entry name" value="Chitin_synth_reg_RCR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28187">
        <property type="entry name" value="PROTEIN RCR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28187:SF1">
        <property type="entry name" value="PROTEIN RCR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12273">
        <property type="entry name" value="RCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="144" mass="16076" checksum="DBE2B58996E99685" modified="2025-10-08" version="1">MPSLNILQPRRTCYYRNNGFYDCDDSNWHSWGRWIALAVIVACSIICFVLIACINSRRRRRHGGRPIYGTGWMAPLPKYSENLPPGHQPYNQSMPQNGYYAPPPPAYGQQSNQALGQSGAIPLQQPQPTYTGDYAPPTGPPPGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT90</accession>
    <name>A0ABR3YT90_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">IEC3 subunit of the Ino80 complex, chromatin re-modelling-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_004918</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000151">
        <property type="protein sequence ID" value="KAL1891576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055449">
        <property type="entry name" value="Iec3-like_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032742">
        <property type="entry name" value="Iec3_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24244">
        <property type="entry name" value="Iec3-like_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14612">
        <property type="entry name" value="Ino80_Iec3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="INO80 complex subunit 3 N-terminal" evidence="2">
        <location>
            <begin position="31"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="INO80 complex subunit 3-like middle region" evidence="3">
        <location>
            <begin position="128"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="263"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="358" mass="39216" checksum="4670BF9958459493" modified="2025-10-08" version="1">MASNETRRKAVDAQHKDDAQKTDLESKQTYRSWKKKYRKMMARFDNASRDNREIYKNEMFAQSIINRISVENDRLLEILLSINETPQIPVNKRFDLSLDLPDDVNNPVPDIDLTPEDEKLMYGKALKQLDRSIIRANYEATKRDSPETVQDLVPAEGKTHPPTFLTMDDINAYIYDIDQRLGIESKPPIVAPDAEMYRVPSSRDSILNNPVSEYNWLRKHAPKTFLQDGVQNPPVAGHSKEAKDKDLPSRAAPGTAGTGGGSASASGGANGTSAPASRGRGSKRGARGVESDHSDDEDAGSRPVKKRRVVAAAASAAADKETGTPVRSKPTASGIKHVKKKAKRQSSAPDAAGVEGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT98</accession>
    <name>A0ABR3YT98_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Chitin-binding type-4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_005124</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the polysaccharide monooxygenase AA13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000163">
        <property type="protein sequence ID" value="KAL1891116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004302">
        <property type="entry name" value="Cellulose/chitin-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052282">
        <property type="entry name" value="Starch-active_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36575">
        <property type="entry name" value="BINDING PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14430)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36575:SF2">
        <property type="entry name" value="CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03067">
        <property type="entry name" value="LPMO_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0186">Copper</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chitin-binding type-4" evidence="8">
        <location>
            <begin position="18"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="190"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="265"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="199"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="230"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="281"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="312" mass="32208" checksum="F7A2D4B58BA97184" modified="2025-10-08" version="1">MKSAVFSIVSMASVVYGHGRVMSPPSRAPGSAFEAACGQSMYNQMTSDPNGNIENMLQNKAATYDPTTCQLPLCRGYKFDDNKDNVQSYTAGQKIDFEVQIAAPHTGIANVSVVDTGSFSTIGEPLISWTNYASSQTGVAADNSVFSVELPSDLPSICGTAGNCVLQWWWFSEVAQQSYISCVDFTTGSGGSDTGSGGTAPSSAAASSSTAAPVAANTPAGNTPAAPTTLKTSTSAPASTPQPEYNAPANDPAILTVIEPTTAPTTAPTTPLANPVIPTGVQPTTPGSQPTSSCKRRRAIRNSGRMYKGASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU39</accession>
    <name>A0ABR3YU39_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Microtubule bundling protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ASE1</name>
        <name evidence="3" type="ORF">Cpir12675_004766</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000143">
        <property type="protein sequence ID" value="KAL1891908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007145">
        <property type="entry name" value="MAP65_Ase1_PRC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19321:SF41">
        <property type="entry name" value="FASCETTO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19321">
        <property type="entry name" value="PROTEIN REGULATOR OF CYTOKINESIS 1 PRC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03999">
        <property type="entry name" value="MAP65_ASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="382"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="458"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="514"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="663"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="737"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="43"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="224"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="399"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="663"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="684"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="698"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="742"/>
            <end position="771"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="810" mass="89953" checksum="18BF520988E2D4DA" modified="2025-10-08" version="1">MDASFLSHQVNSIIEQLHGLFDDIGVPSHDREARETELFAALSDTLNNHVRQVNSEKKDLIEQAQQLISAIRQMEASLEDGKESIREKEDDGLRVTYPLVRCLKVLHEKHQQIHRIHRERFAQVKKLADALESYSSHLEPTFVSIPLPPTNPKAPVPLNFDLSPSYVDKLDVEFTRVYDEYTQRIQAVQNLSEKIISLWAELGTPQVQTDSVVVKHYRDSPEQLGLHKEDLNRLEVKYEKLLNEKKAREKHLNDLKASVESMWSMLGVDEAEKKAFLNANRGCGVRQINEFEDEMSRLSELKRQNLHLFVEDARCKLQELWDALYFSEDEMLEFTPAFSDVYSDALLDAHEREIARLECLREQRAPMLSLIDKHRDLTAQKEELAQSSQDASRLMLRGQKGERRDPGKLLREEKMRKRIAKELPKVVAELRKALEKYEGEFSVPFLVQGERYLDTLEEEAGSTGRKGAASQPRPKTPGAPVMPSNSASSTAKVRPLSKAISMGNLKTNTTAVTAAQSAGRGTAKMTATGAKQQPQQPPRPASTAPGSIGRFGPGSPTRIPARAPLANLKYGKSSPERAPAPRPSSRAEVGTLRHGDAPIMRAPPPKMRDPPRLETPMNPYKAAGLHDNMTGSIVRSVETDDVFGPPSASIMGVSQFSASRYAYASSSSATSSRPDSLLGGPRQVSGSSTQISGSENWETYDDTSEPEPDASDAYYAKLRIAQGKRYAEELAMNRSIEDMKAHSQSHAPSYSHASHHSNGSQGGYSSSASGSKRIRGFPQPVNTHGVLVDADGNRVPSGREWTDEDAGYSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUA0</accession>
    <name>A0ABR3YUA0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GH64 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004949</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000153">
        <property type="protein sequence ID" value="KAL1891472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09220">
        <property type="entry name" value="GH64-GluB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.50">
        <property type="entry name" value="Beta-1,3-glucanase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.110.10">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032477">
        <property type="entry name" value="Glyco_hydro_64"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037398">
        <property type="entry name" value="Glyco_hydro_64_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042517">
        <property type="entry name" value="Glyco_hydro_64_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38165">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38165:SF1">
        <property type="entry name" value="GLUCANASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16483">
        <property type="entry name" value="Glyco_hydro_64"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52006">
        <property type="entry name" value="GH64"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH64" evidence="1">
        <location>
            <begin position="1"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS52006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="388" mass="42917" checksum="11589788C1933A50" modified="2025-10-08" version="1">MVTAQTLDITLRNDTASSNVFVTITGRAMQRNMRPVFLSADGKTPFYPASPSAILQPLNHDVSIALGPPGSTRVVTVPRITGGRIWFCKDASLTFLVNPGPAVVEPSMMNKTDPNYYLDWGFAEFTFNELQLFVNVSYVDFVSIPVSLELENTAGKRMVVEGFPSDGLEQVCRELQKQEARDHAGWGKLVVRTQDGSKHMRALSPNSGFNLFPGLFRGYLEPYVDQVWEQYSRNDRTLVVNTQAAWGDVSGEMEHCHNKLLLSFGGFGKFEKPSTADIFSCSTGPFARTADYTEVKGAIGARLAAALNRTTLVENCQQPEGETESRYYQAERTNHYARICHEVSIRGRGYAFPYDDVSSSKGMDQSGSLWDGSPKMLTLGIGGWRGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUX9</accession>
    <name>A0ABR3YUX9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL10A</name>
        <name evidence="5" type="ORF">Cpir12675_005074</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000161">
        <property type="protein sequence ID" value="KAL1891139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002143">
        <property type="entry name" value="Ribosomal_uL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_uL1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_uL1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023673">
        <property type="entry name" value="Ribosomal_uL1_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002155">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="Ribosomal protein L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01199">
        <property type="entry name" value="RIBOSOMAL_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1891139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="217" mass="24109" checksum="334477E28DBC4B7B" modified="2025-10-08" version="1">MSKITVANVRTQVGDLLEYSLETKKRNFTETVELQIGLKNYDPQRDKRFSGTIRLPIVPRPNMAICILGDQFDIDRAKHGGVDSMSVDDLKKLNKNKKLIKKLARKYDAFIASETLIKQIPRILGPGLSKAGKFPTPVSHADDLSGKVTEVKSTIKFQLKKVLCLGVAVGNVDMTQEQLVGNVMLAINYLVSLLKKGWQNVGSLTIKATMSPPKRIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVL2</accession>
    <name>A0ABR3YVL2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PCI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_004978</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CSN7/EIF3M family. CSN7 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000155">
        <property type="protein sequence ID" value="KAL1891364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045237">
        <property type="entry name" value="COPS7/eIF3m"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350:SF5">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22061">
        <property type="entry name" value="CSN7_HB_subdom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="PCI" evidence="4">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="247"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="267"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1891364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="288" mass="32071" checksum="CFDD56D8F6F80F76" modified="2025-10-08" version="1">MSQTQALISLEPYITLAKSANSPSAAVGLVTRATSDPHTFIFAELLQTNPIKNLATSEKAAYHALLKLFSYGTYQDYLADRANLPDLNDAQRLKLRQLSLLTLAQDQNNLTYAKLMAALELGTTLDLESIVISAVYAGLWDAVLNPQRQVVEVNSVSPLRDLAPGIIPPIIDVLQQWCDRCATTLGDIEAEIAQIKMTAAKRQEYKEYREATKDYVNVHTQAYVQVQTSKMGQDELAMGRELPQHFGSSATSNIRIRQAKRAQAASDDMDLDTNDEEEQKKRTSRRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVN8</accession>
    <name>A0ABR3YVN8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_004700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000139">
        <property type="protein sequence ID" value="KAL1892049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1892049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="127" mass="14066" checksum="63466891EC037767" modified="2025-10-08" version="1">MNTRTSLTETRKVHNEWLAASSQKVGVEACGEVITPISGPTKTEYIKLTNVAYVPDFLANLVSNKLLKSCRGYLNTRNNVLFCDEELVFAHLRELDGHLSVKFGHDTLMELFQSGAFATTSAAHFST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW64</accession>
    <name>A0ABR3YW64_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cleft lip and palate transmembrane protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_004686</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CLPTM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000138">
        <property type="protein sequence ID" value="KAL1892136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008429">
        <property type="entry name" value="CLPTM1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21347">
        <property type="entry name" value="CLEFT LIP AND PALATE ASSOCIATED TRANSMEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21347:SF0">
        <property type="entry name" value="LIPID SCRAMBLASE CLPTM1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05602">
        <property type="entry name" value="CLPTM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="394"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="422"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="487"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="512"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="608"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1892136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="656" mass="73246" checksum="2B59D2DBFE45EE8B" modified="2025-10-08" version="1">MPEPEAAPARAEGGMSLFQRIILGGSLYFALNAGVNKFFNKGQSAVQVQDASGRTINVPGNLDTIPAYQLRPATLDEGAKYAAVPRKVAPIWPTDSLLDIVVTVSPTSAIAPLDHTPPEFIALNESAFHLGDYSDQRIIDAEFPVPRAVQRNGTLWGHFYVGLSGAEIDPTKPDFSPAEAYHFAYPLTQYLPKKPESRTRNLLDDSPPTPEELLAEEELREQGPLIASYYHPNVSFEFVPDLGIMDYAQAHFSARAFTVLESTGARDGSGQNSWYYPVLFVNQFWQLIEHMNVVNETVTTLPIHINLNNIASWKFKAISSIEISNKETLRRSAWGQTAPGGGDGTEIEMIKNVLLDNNPILLGITVLVSIAHMILETLAFGSDIAHYRKKKDNVGISVRSILANVFMQTVILLYLIDNSQTTSWMILGSQVVGIIIELWKITTVVNVVIQPAGPTGWLPYRIAFEDKTVLSETEEKTKEYDQIAFNYMYMAGVPLLLAYAAYSLIYDSHKSWYSYIIATLVGSVYAYGFLLMVPSLYINYRLKSVAHMPGKAMMYKFFNTFIDDLFAFAIKMPFLHRLATFRDDIIFFIYIYQRWAYRVDYTRVNEFGQGGDDENDESTATATEKKDGPAEIEDNSKTGSVVKATGADKSVAKKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW72</accession>
    <name>A0ABR3YW72_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000152">
        <property type="protein sequence ID" value="KAL1891559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="146" mass="15264" checksum="C4FB5A04DD4DCD81" modified="2025-10-08" version="1">MADNEGFEDDLFADLYTDDDPAKSTSTPQIDSTQPNGVTAPASSAPAPAYSASAPALAQDPAFDNINADSAPQLDINTQDDEYEYEDDDDDIDITLGNTSTDAIAVANTTITAFPNQSNQQNDRASTPALSIQGSSKLGVANKEDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWC2</accession>
    <name>A0ABR3YWC2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004458</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000126">
        <property type="protein sequence ID" value="KAL1892690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11392">
        <property type="entry name" value="bHLH_ScPHO4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="2">
        <location>
            <begin position="591"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="485"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="618"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="669"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="485"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="626"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="669"/>
            <end position="682"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="695" mass="75215" checksum="5BBAACDF1CB9C50D" modified="2025-10-08" version="1">MDMLGTPQWNPQGQPPQHSNPDDEFQQFLNMGTLGSLPDTMNFDYTMLPPSAGSIDTAMTGSEHAQSLISPANPAAMAQSHMDPMTTSTHGHSSIPAQMMPSGPNDVITEIDARIQYLQQQRLQQQRQILQEQAKSQHQQRQRRQQQQQQQQQQIQHPQVIASYFSPHQVPPTPQSLELAAGNSNHYYCSTDIQPSVFDSRFSQLKDQPQDSDFTPLVSPAVTPLESQFSVDVAFSVAANYFSPLTSPALHAQNDSSIFTDIRHLGTSSNSLVDRADDWNAPEPSSKKLRKISTKAPTKAPRPKTNVRQSPIVKPQRRRINVTSAAATNPSIAAQVLDEAEEGTNAKLVRSQIEEPEENASVSPEALSDMPPPPLPPLPRAKSGSASPFIQPQNPKSDPTRSLSNGRPAPATPASLMKLPASKASRTPTMVPESIASNGPVDAFRLPDSASFHNSASASDVDTHMHNNNVIDNTARQPAVSLPSSPMFTKPQSTAITSQSPQMLPANSGTTPNPRKTPLLAVRGSKRPNSVKASPALLPKISPHIKPLLPNGAEDAASRLLTTKSNYQNIVEGNNVPGVTYPSELSTNLTSKRTSHKIAEQGRRNRINSALQEIATLLPAPPPKEGSGDSDSKDAGKLPAATPSCKASTVEMAIEYIKQLKEEVAAANRRVAEAERRLRESGIENGDSDVMEKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWT2</accession>
    <name>A0ABR3YWT2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_004384</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000122">
        <property type="protein sequence ID" value="KAL1892801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1892801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="382" mass="42223" checksum="68D749306B4683AE" modified="2025-10-08" version="1">MLPRSSSRSTNSTPPSKCYGLFPTLYHTYRPNVNCSSINTIKLDGTCGGWNNMDSIGASENKSLCMCFCENSSEWSYLPEVPIPNTYCVGPRRCAVSPEITLLLRPQSWKAQLGVRKANALRVGLHSPWSGSETPLPAELVTAEFKLEHGECGYWAFLPIHRKACGVLTDGSPSEKLQCDNPVTTLNFCSDSLYASPEGKVHGLMQFVHTDCQTQQLLRDPTLAISPAISSPEVELGKDTRSAILASWIRVSCQIQMNERLNSTKILPDSQAFDLVATIKGRVMPHEVVGSEGLNLRAKMEVCGKISLYDFSWTASGKDQNQSDWEWAARFVFQQPDLSTIALEYARHCVGSILLDLGGTRDECFFHGLPYNSRGDALMGWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YX19</accession>
    <name>A0ABR3YX19_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GRIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_004611</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000134">
        <property type="protein sequence ID" value="KAL1892288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019459">
        <property type="entry name" value="GRAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000237">
        <property type="entry name" value="GRIP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18921">
        <property type="entry name" value="MYOSIN HEAVY CHAIN - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18921:SF2">
        <property type="entry name" value="THYROID RECEPTOR-INTERACTING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10375">
        <property type="entry name" value="GRAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50913">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GRIP" evidence="6">
        <location>
            <begin position="405"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="451"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="515"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="112"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="472"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="518"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="531"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1892288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="543" mass="60476" checksum="1AF62690D8E8E4F8" modified="2025-10-08" version="1">MSPAPSDTVSALQASGTGKKKNNKKKSKNAKSKDATSIESQPAAEDAPKADAEVMESEPEPSTPMTQEIPIRPASQETTFDTSNAKPNGTNPNPHPDPALQAENQAPLQDEVEKLRSQLSALQESHDAEVAQLKEDIDESTAAKEQAEEQYEALRDRVEKIKSTLAERLQRDRVELEEAKERIDELEAQGEELRGQTEEANKRVESLELELQEATRELTGLRSRNNLSAQNWSKEKEDLMIANQRLRDELQSTTNAMSEWEVIAMEERALKDSYVDKITSLEEQLGQLNEAYLSINSIKDTQDQSISSLQRALSELQDTRKRELRDMVETHEEQLKALKVAAQKVNKQLAAALAEKETLSRELQRTAPFEKEVNEKNLLIGKLRHEAIVLNEHLTKALRYLKKTKPQDQVDRQIVTNQLVHFLSLDRSDPKRFQILQVMASYLQFTDEEREQAGLARPGTSSNSLRLPASPFSRTPSSPSLHSDFFSDPSVLTATTGASSKETLAELWANFLERSAEEGGGPAGGKGRQGSVSSVGTRSDTRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXM1</accession>
    <name>A0ABR3YXM1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Pyruvate kinase</fullName>
            <ecNumber evidence="4 14">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">PYK1</name>
        <name evidence="17" type="ORF">Cpir12675_004284</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>pyruvate + ATP = phosphoenolpyruvate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the pyruvate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="4 14"/>
    <dbReference type="EMBL" id="JAWDJO010000117">
        <property type="protein sequence ID" value="KAL1893093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00288">
        <property type="entry name" value="Pyruvate_Kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="entry name" value="Pyruvate kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018209">
        <property type="entry name" value="Pyrv_Knase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004491">
        <property type="entry name" value="PRK05826.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004978">
        <property type="entry name" value="PRK06354.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PYRUVATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="PK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00110">
        <property type="entry name" value="PYRUVATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 14" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="8 14 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12 17" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate kinase barrel" evidence="15">
        <location>
            <begin position="31"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate kinase C-terminal" evidence="16">
        <location>
            <begin position="392"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1893093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="527" mass="57299" checksum="DAC8EE5EC3A17959" modified="2025-10-08" version="1">MASVQQHLDAQGKIAWLAGLDTAYAPERNYRRSSIICTIGPKTNSVEAINNLRKAGLNVVRMNFSHGSYEYHQSVIDNTRAAEKAYAGRQVAIALDTKGPEIRTGNTAGDADIPISGGTIMNITTDDKYATACDASNMYVDYKNITKVIQPGRVIYVDDGVLAFEVLEIVDDKTVKVKARNNGFISSKKGVNLPNTDVDLPALSEKDKSDLRFGVKNNVDMVFASFIRRAQDVRDIRTVLGEEGKHIQIVSKIENRQGLNNFAEILEETDAVMVARGDLGIEIPAAEVFAAQKKLIAMCNIAGKPVICATQMLESMIKNPRPTRAEISDVGNAIADGADCVMLSGETAKGAYPNEAVSEMSQACLVSENSIPYVAHFEEMASLIQRPISVTESCAMAAVRASLDLGAGGIIVLSTSGDSARMLSKYRPVCPIFMVTRNASASRYSHLYRGVYPFLFPEAKPDFAKVNWQEDVDRRIKWAVQEALALKVLKNGDRVVVVQGWKGGMGNTNTLRIVTADPENLGIGQQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXS5</accession>
    <name>A0ABR3YXS5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleolar protein 16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">nop16</name>
        <name evidence="9" type="ORF">Cpir12675_004679</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the biogenesis of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the pre-66S ribosomal particle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NOP16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000138">
        <property type="protein sequence ID" value="KAL1892129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019002">
        <property type="entry name" value="Ribosome_biogenesis_Nop16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13243">
        <property type="entry name" value="HSPC111 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13243:SF1">
        <property type="entry name" value="NUCLEOLAR PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09420">
        <property type="entry name" value="Nop16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="76"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1892129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="254" mass="27985" checksum="CB280AFE273C6B61" modified="2025-10-08" version="1">MGRELQKRKNRSSRPKVVVPNSRKKALNPMGNNIIAKNWDKKQTLSQNYRRLGIAARLQAPTGGVEVTVAEATNAVPKPKIPSTPGLSSALGGAASGTPAIREARVERDADGRIIRVISSGPSTDIQGFKPLNDPLAAYDSDCDNDNSTPTHATITNTSTAASTWEDWAGISDNENDNEVVKALVRQSRLPVANQTRFQSEQENEWLNRLVAKHGDDVRAMAWDRKLNPFQQTVGDLTKRLKRWRKVQAEKGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXV7</accession>
    <name>A0ABR3YXV7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ATP synthase F(0) complex subunit e, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">TIM11</name>
        <name evidence="12" type="ORF">Cpir12675_004208</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Subunit e, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. Part of the complex F(0) domain.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) and CF(0) have multiple subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ATPase e subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000114">
        <property type="protein sequence ID" value="KAL1893230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008386">
        <property type="entry name" value="ATP_synth_F0_esu_mt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05680">
        <property type="entry name" value="ATP-synt_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="4 11" id="KW-0138">CF(0)</keyword>
    <keyword evidence="5 11" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1893230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="89" mass="9964" checksum="1DE9A1D7849EDD21" modified="2025-10-08" version="1">MSSATTLNVLRWSSLAFGVFYGFTHQRAIRSEEKAAVAKHEYEHKESLIAKAKAEYAKNKNPAPASSQSVDFTDPNFDFEAFFNNMAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXX3</accession>
    <name>A0ABR3YXX3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004223</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000114">
        <property type="protein sequence ID" value="KAL1893245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047049802" evidence="2">
        <location>
            <begin position="19"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="174"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="486" mass="49613" checksum="168386A60088135A" modified="2025-10-08" version="1">MHVSAIFAASALMAVASGAPIPMSHRRASTESQYLIQPVKNLTESIPVMSPVASTSLCTDSTSVVSTASPTVTAVSSDPWAPSSLSTSVIFRSPTTLSTATASKLTSSPTSIPIPTGSHSTVMRAGPAYDPAEYRAPVRSASPSGRWLTWSAGPLVPLSSYTRSSPTATAASSSISALSTSTSTSEPNFSSSSTSLTSAVSLSDPTAPVETYPATSQWRPFTASSSLPQSKDNSVSLSNSTALTTFHVTSTSLIPITTALVASITTTEDSASANLLAALSIPQHTITASSLSSSITSIISTTTVFVTYSTANLTVSADLTAAPRFSSVSAFGTAINNISTSAAIDGWRSFRGNYSLPWSSLSPASPSPAPLTALPTAVHSSPMLSGGGSARSIALASATQAPSWLSGTLSVPTVAATASPTVTDSLVDATVTSTKTITIIPTPAGVTKTNSARLYGEYPLLCIELRGNRTVPSVIPSELLEFLQDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYD7</accession>
    <name>A0ABR3YYD7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Isocitrate lyase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ICL1</name>
        <name evidence="11" type="ORF">Cpir12675_004161</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate</text>
            <dbReference type="Rhea" id="RHEA:16809"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57429"/>
            <dbReference type="EC" id="4.1.3.30"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-threo-isocitrate = glyoxylate + succinate</text>
            <dbReference type="Rhea" id="RHEA:13245"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="EC" id="4.1.3.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000112">
        <property type="protein sequence ID" value="KAL1893378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004451">
        <property type="term" value="F:isocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006254">
        <property type="entry name" value="Isocitrate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018523">
        <property type="entry name" value="Isocitrate_lyase_ph_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01346">
        <property type="entry name" value="isocit_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21631:SF3">
        <property type="entry name" value="BIFUNCTIONAL GLYOXYLATE CYCLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21631">
        <property type="entry name" value="ISOCITRATE LYASE/MALATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00463">
        <property type="entry name" value="ICL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001362">
        <property type="entry name" value="Isocit_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00161">
        <property type="entry name" value="ISOCITRATE_LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="8 10 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1893378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="543" mass="59756" checksum="04D207A5B44CFC35" modified="2025-10-08" version="1">MAANNMLSISVDPSQEDALFQQEVEAVKKWWSESRWRYTKRSFTAEQIVEKRGNLKIEYPSNAQAKKLWGILEKRFAGRDASYTYGCLEPTMVTQMAKFIDTVYVSGWQSSSTASTTDEPGPDLADYPYTTVPNKVGHLFSAQLFHDRKQRQERLSVPASERAKLSNIDYLRPIVADADTGHGGLTAVMKLTKLFIEKGAAGIHIEDQAPGTKKCGHMAGKVLVPISEHINRLVAIRAQADIMGVDLLCVARTDAEAATLITSTIDSRDHSFIIGATVPGQKPLVDVMTAAEASGKTGAQLQAIEDEWVAAAALKRFDDAVVDALKKAGKSDAVTAEFRAAAKGKSNAEARELAKKAGVDVFFDWDAPRTREGYYRLKGGCDCSINRAVAYAPYADAIWMESKLPDFKQAEDFAKGVHAVWPEQKLAYNLSPSFNWKTAMSHANQETYIRRLASLGYCWQFITLAGLHTTALISHQFSEAFSRIGMRAYGELVQEPEMDGGVDVVKHQKWSGANYVDELQKMVTGGISSTSAMGKGVTEDQFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYG9</accession>
    <name>A0ABR3YYG9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phosphoribosylformylglycinamidine synthase</fullName>
            <ecNumber evidence="3">6.3.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Formylglycinamide ribonucleotide amidotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Formylglycinamide ribotide amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">ADE6</name>
        <name evidence="17" type="ORF">Cpir12675_004139</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the FGAMS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.3" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000111">
        <property type="protein sequence ID" value="KAL1893401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004642">
        <property type="term" value="F:phosphoribosylformylglycinamidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01740">
        <property type="entry name" value="GATase1_FGAR_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02204">
        <property type="entry name" value="PurL_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.750">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase, linker domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="entry name" value="PurM-like C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="entry name" value="PurM-like, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00419">
        <property type="entry name" value="PurL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040707">
        <property type="entry name" value="FGAR-AT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055181">
        <property type="entry name" value="FGAR-AT_PurM_N-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010073">
        <property type="entry name" value="PurL_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041609">
        <property type="entry name" value="PurL_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036604">
        <property type="entry name" value="PurS-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01735">
        <property type="entry name" value="FGAM_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003672">
        <property type="entry name" value="PRK05297.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10099">
        <property type="entry name" value="PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10099:SF1">
        <property type="entry name" value="PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18072">
        <property type="entry name" value="FGAR-AT_linker"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18076">
        <property type="entry name" value="FGAR-AT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22689">
        <property type="entry name" value="FGAR-AT_PurM_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13507">
        <property type="entry name" value="GATase_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01211">
        <property type="entry name" value="GATase_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109736">
        <property type="entry name" value="FGAM synthase PurL, linker domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="PurM C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="PurM N-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82697">
        <property type="entry name" value="PurS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4 17" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphoribosylformylglycinamidine synthase N-terminal" evidence="15">
        <location>
            <begin position="42"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoribosylformylglycinamidine synthase linker" evidence="14">
        <location>
            <begin position="184"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="PurM-like C-terminal" evidence="13">
        <location>
            <begin position="451"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="domain" description="FGAR-AT PurM N-terminal-like" evidence="16">
        <location>
            <begin position="683"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="domain" description="PurM-like C-terminal" evidence="13">
        <location>
            <begin position="882"/>
            <end position="986"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF18072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF18076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF22689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1893401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1366" mass="147681" checksum="7D9E3A20DE501162" modified="2025-10-08" version="1">MDFLTLVGGPALTASQAEEIKTRINKTAGLPSNVIKVEGVWMYYVHLKASSSASVSEVQSKLAKWLELPSQDGLLDFTQTAASKTFFITPRNISPWSSKGTSISHVCGLTDQLRRIERGHTVTITYESDVASSDIAFKDILHDRMTETFDSTTPDLEAMFVEDKRFPLEIVNIFGKESSPLDTLRAYNKECGLALDESEMAYLVEVFTKLGRSPHDVELFMFAQVNSEHCRHKQFNASWTIDGVKMPNTLFGMIRNTHKKNPQYTVSAYSDNAAVLEGETASFWAPDYSTGSWKLTKEVVHILAKVETHNHPTAISPFPGAATGSGGEIRDEGAVGRGSKPKAGLAGFWVSDLLIPDESTPWEVDLGRPSHFASSYDIMMEAPIGSARFNNEFGRPCLTGCFRTLLTNVGSGDSPEWRGYHKPIMIAGGVGTVRPQHALKKEGDVTEGAHAIVLGGPAMLIGLGGGAASSSASAEEAAELDFASVQRGNPEMERRAQMVIDACVSLGDESPISMIHDVGAGGLSNALPELVKDAGFGGSFELRQIHSADGSLSPLQIWCNEAQERYVLLVNKEGLNRFISICRRERCPYSDVGVVLPRDSNGDSKLILSDRDSKEQPLPIDLPMSTLFPEGRRLERVVESRKLTLSAFDAVTSIQKIAGENASLSDYITIATERVLRMPSVGSKSFLITIGDRTVGGLSVRDQMVGPWQTPVADCAVTAVSYQIGANTRNGEAMAMGERPPLALVSPAASARMAVAESLTNLAAADLINGLERVKLSANWMAAVNHAGEGAGLYEAVNAIGMELCPKLGLSIPVGKDSTSMKSSWKDKKTGESKSVTAPMSVIITAVSVVEDVRLTWTPQLRRVEDVGETILLYVDLAEGYRALGGSALAQAFGQVGNDVPDVRSADLLVDFFDAIQQLHKSGIVLAYHDRSDGGLLATIAEMMFAGRCGVDIMMQHISKSPSPKDMLDSLFNEELGAVFQVRKKDEINFKRCFATCGPPAGLIKVFGVVKPKSQQSLTVRYADAPIVDLERGQMQQWWARTSYAMQRGRDNAACAEAEYASILDSADPGLSFNLTYKPAENIMPLTASLSSLVMKAPRVAILREVGVNSHAEMAFAFKAAGFDPVDVHMSDILGGRTLTDFVGLAVGGGFSYGDVFGAGVGWAQSILEHKGARSEFEAFFKRADTFALGVCNGCQMITRLQELIPGSQGWPTFTDNLSQQFEGRVAMVKIDDSVAERAGHAPSVFFHGMNGSALPIVVSHGEGRATFKKDADLNVLDTEGLAPLRYVDGRLQQAGPENYPANPNGSPGGIAGVRSRNGRVLALMPHPERTIMADVGSYIPREQAEEWGEFGPWVRMFKSARKWVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZG0</accession>
    <name>A0ABR3YZG0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lumenal Hsp70 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">LHS1</name>
        <name evidence="6" type="ORF">Cpir12675_004431</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000125">
        <property type="protein sequence ID" value="KAL1892699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10230">
        <property type="entry name" value="ASKHA_NBD_HSP70_HYOU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639">
        <property type="entry name" value="HSC70CB, ISOFORM G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639:SF3">
        <property type="entry name" value="HYPOXIA UP-REGULATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046854070" evidence="5">
        <location>
            <begin position="24"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="612"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="757"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="795"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="920"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="757"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="797"/>
            <end position="819"/>
        </location>
    </feature>
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            <begin position="826"/>
            <end position="838"/>
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        <location>
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            <end position="958"/>
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    </feature>
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        <location>
            <begin position="959"/>
            <end position="982"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1892699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="982" mass="106993" checksum="E7F0F2383FCA093C" modified="2025-10-08" version="1">MRSSSPLLKALGVAFFCSSQTLAASAVIGIDLGTEFIKASLVKPGIPLEIVLTKDSRRKETSCIAFKPAPGTPKLDEYPERSYGSDALALAARFPSEVYPNLKTLLGQSLGSPVAQEYIKRHPALQAEENAERGTVAFGSKAFAPGNNIWMVEELLAMELQSIRKNAQALAGSDSPISAAVITVPPFFTTEEKRSVHLAAKLAGLDILDLISDGVAVGLNYATTRQFPSVSDGLAPEYHLVFDMGAGSTKATVLRFQSRSIKDVGKYNKTVQEVQVMGYGWDRALSGDVLNALIIDDMAAKFVETPKAQAISATSEKLLTHGRATSRLTQESQRLRHVLSANVGTQANFEGLFEDIDFKYKLTRTDFEEMVAPYIERVGSTVQSALTKASLEVSDLTSIILHGGASRTPFVRRELEKVIGSAEKIRSSVNSDESAVMGAVFRGADISPSFRVKEIRLFETTPYSTGVKWINVEGKLRHQRVWSPLSVLGAAPKEVTLPALDNFEATFYQTIEDEDREVMTLQTTNMTASVAELKGKFSCAEADIRFKVAASLSREDGEIIVSKAYVECEAEIADKEGIMGGVKNLFGFGKRDQKPLVGEGSIDTDDHVKEAEEIMSSSSKSADDSESTPAADTKETKKEVVSVPVGFATSEKGISSLSKASLKTSLNRLKAFEASDLARRQREEALNQLEAFSYKASELPETEGWQKYATEAERTSVLEKSAEYGDWVYGDGADAAKADLDAKLEDLQSIVNRVTQRIEEHEKRPELLEKLQSTLSQSTDYVSSLRAGIKEYKDWHASASASSDPSSEATASPSTTSADADSDSDADSKDAKDAKKSSMQDVIDEIGPVPPVHEEADLQDLDKLVDEVRTWLDETIPKQAALNPTDDAILTITQLDRFLDRFERAGLELTMKGVRNFERKKEQEAKKEKAAKAAKDKAAKEAAKKAKEEAAAAAKKDVENDEDDVSAEDETTDETADDHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZP5</accession>
    <name>A0ABR3YZP5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003928</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000101">
        <property type="protein sequence ID" value="KAL1893860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="222" mass="23318" checksum="1A61FC9F44918769" modified="2025-10-08" version="1">MSTKEMPPPSEFESSSRGTLTPSPTPPVPSPQPISAKIAMLFIRARSSLNLLSLAAGITIIGLSARNLHIYNETHLAANFLLPLWPTNINIGSTIAMIVAGAVVTVCSAVAIALDQAQKNSHTTVGASAAVSVLSFVSAMSAVIVHYAGTSASADTIETWSCKWNHISMLSEPHFGGICLHAKATAGLAVALMPLQLLIMAVVLLGFMADKTGRWRSSMPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZP7</accession>
    <name>A0ABR3YZP7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Autophagy-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ATG22</name>
        <name evidence="12" type="ORF">Cpir12675_003910</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
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            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ATG22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000101">
        <property type="protein sequence ID" value="KAL1893843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="MFS_Atg22_like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044738">
        <property type="entry name" value="Atg22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024671">
        <property type="entry name" value="Atg22-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050495">
        <property type="entry name" value="ATG22/LtaA_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23519">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23519:SF1">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11700">
        <property type="entry name" value="ATG22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="8 10" id="KW-0072">Autophagy</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <keyword evidence="4 10" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="172"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="356"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="390"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="428"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="467"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="498"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="527"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="210"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="73"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1893843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="587" mass="63513" checksum="B4340C7408A7B7D9" modified="2025-10-08" version="1">MPSPDPDPNSEEDPLASPALRYPGEDIRPTSSKEISGWYMYAFASEVYVICASFIPILLETLSRENGHLLHHPDRPCPASHDRLSSSPPDPTPAASAVGDVCVVTFLGLDINTTSFAMYTFSVSVLLQALVVVSISCAADHGTGRKQMLLAFAALGSISVMGFLFVTSRMYLIGAVLTIISNTSFGASFVLLNSFLPLLVRNHPEVARLKSGRTDDNSNANSSRRTSSDETPLLSDDSVASVSEITSVEMRLSGQISSTGVGIGYCAALFVQLICIAVVIMLNNTTWSQRVVLFLVGLWWAVFTIPSALWLRPRPGPPLPRPIYLNGRSFSWRVALSDASQSWINLWRTVKLARRLLDVVLFLGGWFLLSDAIATTSSTAILFAKTQMHMTTWALGMINVISTVSGVIGAFSWALISRSFGLQPHHTLLACIALFELVPLYGLLGYLPIVQRWGVGGLQQPWEMYPLAGVYGFVLGGLSAYCRSVYGELIPPGSETAFYALYAITDKGSSVFGPAIVGFIIDRSGDIRPAFWFLAAMVGLPAVFMSLVDIARGKHEGKRLAAQLDGLKTGYPEGTGSVDRHGEDEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z0H7</accession>
    <name>A0ABR3Z0H7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Exocyst complex component Sec8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SEC8</name>
        <name evidence="8" type="ORF">Cpir12675_003783</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SEC8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000095">
        <property type="protein sequence ID" value="KAL1894141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039682">
        <property type="entry name" value="Sec8/EXOC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007191">
        <property type="entry name" value="Sec8_exocyst_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048630">
        <property type="entry name" value="Sec8_M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14146">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14146:SF0">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20652">
        <property type="entry name" value="Sec8_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04048">
        <property type="entry name" value="Sec8_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2 4" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0645">Protease</keyword>
    <keyword evidence="3 4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component Sec8 N-terminal" evidence="6">
        <location>
            <begin position="224"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="Exocyst complex component Sec8 middle helical bundle" evidence="7">
        <location>
            <begin position="473"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="180"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="521"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="28"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="80"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="143"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="531"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1894141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1238" mass="136851" checksum="FDA0747F936F5BD6" modified="2025-10-08" version="1">MSADRRYAPPNGRPTQRTNGYGNFGPAPNLQQQQQQQPQRDPNPLPNDYDAYGDGYGGSNGNGAPPPRGRPMGERPALRPSPSSNMISMSNDGGMDMRAGNMGYRNGSVGGGSESSGTAISMRSARERFDSPGRVSLGNRSRSPQPGSQAPASQAAPPPSQPTMRSMPSRNRLNERLNARDASPSQHSLNHQSSRLLQQHQYQQDSAAVEQRRVPESNAEREIIQVLEHIRKEWPALCTSDCVPVQLALQLLDNSSVGRAHEYRNFQHTYMMLQNSLKGVVHEHHQGFNSSIGTFHQIQNSIQESQMKVAGLKETLLATKTSLCNPDSELKKLSVTSQMYDGLIVVLDELEDLRLVPDQLEARISEKRFLTAVEVLQTALRKLRKPELDDIGALGELRSYLANQETALMDILVEELHEHLYLKSPYCQERWQSIAKNHGTEAFANGGSNPPPFEQLLDNMDFEKAATEDLAKNPEADTFEYIGLLVEALNKLGRLQNAVENLKQRLPVELFQIANETINEVDQRHPSSLRGGSGGSGSGSSGGSGGNDSGSGSGSGSGSGIGGGSNGLGIYGSRETQLRADVIYDLLWTLYGKFEAIAEGHRVFHESIKALIRREGAGNNSALLGSFKELWNLYQNEIRTLLNYYVTSHADVYQFSTSPNPSAGSGKVDGIRDHLFRFSDTDSKGIELATEMEALDLIIQAAVPGLTGREKDEKKSALGLRSAQKSTGLGFGDRHGTGTYKSLVDPSVFNMSLLLPPTLVFLHRLKGIVPPGSDLATSTLTSFLDNFLVNVFQPQLDETLAKLTDTVFNEPDSFQQDQNWSMVAKKPIFKGTSSFFTIVTAFCRMLGTIPHDQALSSLLVSQMMRYYDCVFTWFKGLVTKTAQAQDSSNAPLPDDDIRNLRICARFALSESEINDVMHSRWAGDLNDPVLLEKETYLLVAHVATRGLELSDIIQDKDTISSLCLIYTSMKWLAIKSQGLRHITHQETDTSQNSLPRATSQRWSLMHDKTPDKGGPVYLPLTQDTVQTFDRIVKSYQELASTALRTLHMEIRCQIMHSLNVVLSPTTTPYILDQDILEPDAQILKLNNNLVSYDEAVSRFLHAREAQYIRSGLGRLISNILVTNASIASPMNAQGYGRMQLNILVLQQNLKNIEDGVDLKRATSYFAMFSQGGDKILEAAHNMKSLPDEAPDKFTGEELKKLLELCYSEQLSDPERGVAAAARRQMDDKMQNLDEIMRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z135</accession>
    <name>A0ABR3Z135_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003882</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asaB hydroxylase/desaturase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000099">
        <property type="protein sequence ID" value="KAL1893906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044053">
        <property type="entry name" value="AsaB-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041278">
        <property type="entry name" value="CmcJ_NvfI_EfuI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598">
        <property type="entry name" value="BLL6449 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598:SF1">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_3G13140)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="312" mass="33647" checksum="AB9AAF53DCED8B63" modified="2025-10-08" version="1">MAAISTVPIPATTSSASQIPRGDVHATLNFYSAPADGSPPVNYVSANGHKTNFGEDPQRVLIRDLRGRPAPALDIEGFQLVRPDGVGVGGLETAPESVLTSATAAIATGAHDQDETDAAIRTTYYPEVEALLLASIPGANKIHIFDHTIRRAVPGAPRGPVAMVHIDQTLSSVQKRVRRHLPEDADELLRGRYRIINVWRPIGAAVESHPLAFAASSSVSDADILPVRHQYDNGYTGETAAVKFNQAQEWWYLSGVTLEERILIECFDSEALKDGSLVKGGRTPHTAFEHPETAAEARPRESIEVRALVFGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z186</accession>
    <name>A0ABR3Z186_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mannosyl-oligosaccharide glucosidase</fullName>
            <ecNumber evidence="1">3.2.1.106</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Glucosidase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_003731</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>N(4)-(alpha-D-Glc-(1-&gt;2)-alpha-D-Glc-(1-&gt;3)-alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] + H2O = N(4)-(alpha-D-Glc-(1-&gt;3)-alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] + beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:55988"/>
            <dbReference type="Rhea" id="RHEA-COMP:12806"/>
            <dbReference type="Rhea" id="RHEA-COMP:14355"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:59082"/>
            <dbReference type="ChEBI" id="CHEBI:132537"/>
            <dbReference type="EC" id="3.2.1.106"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Glycan metabolism; N-glycan degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 63 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.106" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000093">
        <property type="protein sequence ID" value="KAL1894303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031335">
        <property type="entry name" value="Glyco_hydro_63_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004888">
        <property type="entry name" value="Glycoside_hydrolase_63"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054491">
        <property type="entry name" value="MGH1-like_GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10412:SF10">
        <property type="entry name" value="GLYCOSYL HYDROLASE FAMILY 63 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10412">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03200">
        <property type="entry name" value="Glyco_hydro_63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22422">
        <property type="entry name" value="MGH1-like_GH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="1" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mannosylglycerate hydrolase MGH1-like glycoside hydrolase" evidence="4">
        <location>
            <begin position="470"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 63 C-terminal" evidence="3">
        <location>
            <begin position="748"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="263"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1013"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="265"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1019"/>
            <end position="1037"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU369107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1894303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1142" mass="131201" checksum="899221F20AE87799" modified="2025-10-08" version="1">MVITESWNRTSNEELRLREDREKVKYWKRWGPYVSERQWATVREDYSADGDAWSYFTHDDARSRTYRWGEDGIAGVCDSHGRQNIAFAFWNGKDKFLKERLFGLSNPQGNHGESIKEAHFHVDNTPTHSYMKFLYKYPQDEFPYEDLIAENARRGKQEPEYQLLDTGIFENDRYWDIEIEFAKDTDDPEEMVFRVLAYNRGPEPAELHILPHVWFRNTWSWGITEESNKPKPYARYCEKDIAETTCPDIGPRYVLFSPSPGVVQKAQQEPSAQNCSEDPENLTTEEDDDVVPEMLFTENETNAKLLYNSENKQPYVKDAFHRYVVNGEEEAVNPDQEGTKLAAWYQFTEDGGVRPGECAIVRFRLSKNGVFRDNEEEEIDTLITLRLDEANKFYESLTPASMPYEMRQIQRKAFSGMMWTKQHYNFVWKEWANGDATNPPPPESRKNIRNQNWRHMHCDDILSMPDSWEYPFFAAWDSAFHCIVLAMIDPEFAKKQLDLFTREWYCHPNGQIPAYEWNFSDVNPPVHAWATFRVFKIERKMYDRQDLDFLERVFQKLLLNFTWWVNRKDVDGKNVFEGGFLGLDNIGLFNRSEPLPTGGVLEQADSSGWMAFYCLSMLNIALELAKHRTIYEDIANKFFEHFIMISDAMTFRAGQVEETSLWNDEDGFYYDAISWGAPWVKQLPVRSLVGLIPLYATLTLEPELIEKLPAFKKRIEWFTKNRCDLAERNMASIAKRGNQNRILLSIVSKDRLSKILKRMLDENEFFSDHGIRSLSKFHQANPVTMEVNGQTFGVSYVPGDSDSGLFGGNSNWRGPIWLCVNFLLIESLQRFHLFYGSDFRVDCVSTKDGRENKTVESMHLGQVADELRRRLLSIFLRDEDGRRSTNGGNNILDFDPHWSEHIWFYEFFDGDTGRGLGACHQTGWTGLVARLIHDGCLNAALPMTPKTTDQAMSHYFDDIVHRHLSKSHTELRRSLSSRSIGARSDFDNEPLSKLEMTEDQNNRISVSKTIKNAVPREPPSNNTEENLDRNTPFNHTANGNGIYVDNSTDAYADNSAGNSADAYAGNSTNIYTNGSTANSNGAVIATNEVVVGGDSSSLFVGAGISTNGNFTIADRTGLNRQTAGLSINTSKKTSMFEVGPED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1B7</accession>
    <name>A0ABR3Z1B7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003974</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000103">
        <property type="protein sequence ID" value="KAL1893818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="315" mass="33800" checksum="D3B52CB97CF85AF4" modified="2025-10-08" version="1">MAGSMNSSKNRQVSITSANIDALDSPSTQHTKLRSQTLIRKKPATSQATIQKQAKMEEVTGDSETEDAKVALGNDGNGSQCPLGKTLSISAHSRRVEVMAMALAVLSNLGGWWVGYTLLQEWAKPQLAGLVYHPQPKELAQLIGWRVFYTASAWLAACDAADIAAMGVLGASPTSFAPRLVLEFFTGGQVVTTAYPFGYVTILPAALICGTALNWLVFVPYVDIGLRPEDEELACFNPSTATLRETIVFNFWGYTTRTKVGLRRILAAMLSSGVGTCMLLQYGLKTTYQGAVAYSSIWVVAALLAGIGMGYTGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1H9</accession>
    <name>A0ABR3Z1H9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Gastric mucin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003886</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000099">
        <property type="protein sequence ID" value="KAL1893910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="260"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="992" mass="108859" checksum="09A64B7BBF1E6739" modified="2025-10-08" version="1">MARKASTIDHDLLEKGSIVVFEGPSEVVSTQLRLLPASPHILVLPGLQNYLPEHLETNVDCRTYVRHIHNAAAARHDAAVDFIRAGSPDAKRLVFLNGGTARAYAMCIQYISDREAHGSISIAETHFRGLVGGGVAAFTSDSPEPTLDDDCFGSTFEERMVNVMRAAEALDEKTSDLQSEPYSACSIRPRSMSLPVYGFTDRFGDLAAFYMFGSPLNEAEIEEVDDATRELFSRVTSVFAAAANDSPPRHERPVSPTETVSSDRSSCRDSCVSPTTPYPPRRKQPVDNKIVEAWASDLRVLLPIPVKPPQRTRSLQFKPVKKTPKSKAPPSTPPSKGELLSSARVPHDGRPISCIDMPHQKDAQSQGPQSLSPPKFHKCFKSPFGQEDNCPSLMDHRESIRRESMRRESIRQEAVRRASAAVAAAAAVPSQLLPFTEDMVVFFRDESHESLLERVVSNFQTGIFPCVAPTPSDHRRPSVPRVVISRPASCVISPPPMPYLLNDGIRRASSPQTRIFKEDYDFGGSLKKTVDEEEEMTGTALPISDEHLLSSFPPTPAHTPPIGPQPENLSSRFHVLPISHITTAVGVQNSLRAILDKQFPRSEVGYQQFCPMLPELNGLWKPVFRESISSNGHRERRKVDFILALGAQNGVDKSFSGSVSRKLEQLGTKPTGESRSGRLDLRYLIVNAMQAFTSQRLMYQTEDNPFTNPYLLASLVIPHLETFLAAHTHIRYLLLDYPPDHLSTILSIQKLIGSDIMKVAQIFDANGTEKAPFNPLPCRPPSPTATSAYSSFTPSSDQPTLSRANLLLSSTATPSETDSFLHAVSSVLISISDFYDNTAAVAAAAAATAAAVAVTAEDEIFCPPLSPAGRTPIKGPFSPFPRRGSAQSTHYLPPTPISSARGGGFKLSRPPKGRGFMSRNISPASSKIADLMPDVIVTDPAVEINVSDWDDFDLEDDVELEADERRFVPLFMRRRPSRLMGNNKALRFLGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1N8</accession>
    <name>A0ABR3Z1N8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003637</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000089">
        <property type="protein sequence ID" value="KAL1894511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF50">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="3">
        <location>
            <begin position="116"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="235"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="359"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="368"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="466" mass="51368" checksum="FD8DBD61D8334A28" modified="2025-10-08" version="1">MLTDFDAASKLPKLGATFTRANSVSVSASSSSLVSKTRTMSSSGQHSASASSEALLSKPFVLKNSRTYINDVTLPYPLPVDLTELHRQSLRTLMLIQLFRVPVCCPNLTTKPPTRVLEVGCGSGFWSMMCHRYFRNRGHNSVSFTGIDISPLSLSSTSGLRRPDQDMKWRFIQHDIRITPFPFASEEFDLIMVKDLSLAITNDMQQKLMDEYIRLLSPGGILEVWESDHTIRMLRPPPPIASGSSPPATAAPGAGSTSSGTVTTLAEEEADRASAITMGAYVMSPNTALSAALNKFLAEYNTWLTRALELRDICPVPCTLVGPMLLQESESLTDVRSCRLVVPFSDVRWEKEGIGGVQTCGGANNSHNHNHSHSHSSTSKHRSKSRHHSGKTFSGLSPGQMALRRTALMTVIQEIQALESVLREVNGKSQDEWDTWMGKMMHDLLQENGTSWGECLEIGAWWARKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1Z3</accession>
    <name>A0ABR3Z1Z3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Sulfate transporter family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_003563</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000087">
        <property type="protein sequence ID" value="KAL1894625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052706">
        <property type="entry name" value="Membrane-Transporter-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018865">
        <property type="entry name" value="STK19-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43310:SF4">
        <property type="entry name" value="AFR304WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43310">
        <property type="entry name" value="SULFATE TRANSPORTER YBAR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10494">
        <property type="entry name" value="Stk19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="385"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="418"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="466"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="490"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="545"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="628"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="654"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="685"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="8">
        <location>
            <begin position="754"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="7">
        <location>
            <begin position="952"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="108"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1100"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1117"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1134"/>
            <end position="1145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1894625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1317" mass="145418" checksum="4BB58A4EEACDC29C" modified="2025-10-08" version="1">MSSFSSWRNRASSVNAQDHPETAQYGSITDAANGSRAKRQRSNSFSVASVENQPMRSFVTGAGRNKVGLQIDSSENARSVRQDTADLASYFLADRKEPLSTSFLARQRSVQNTPRTSLDEDRFTAHISSPHLRSPNNQNTQWETDSEADPELDALIEDADEGPSVLSNMLRRSPPDAFNGAASTACVIDDGFVDNSTRRPRSGTYAGSTSGDVETTPLLGVIRRGSMSSRRSLYGSSLEDHIDDIEAQKLHPHSTPSRVPSQGANIPQNIAWNPTKWDYPAIYHNAVIRPAHCLPAVIVGLLLNILDALSYGMILFPLASPIFSQLGSAGISIFYVSTIISQLTFSTGSIFRGGVGSELIEVVPFFHNMAGKITRIVGEDKPEEVIATTIVAFSASSIVTGLVFWMMGKFQFGYMVGFIPRHILIGCIGGVGFFLILTGFEVSARLDGGVQYDLETLRQLMDPETLWQWVIPFFLAIALFWGHSKVKSKYFLPLYILGIPFIFYFFVLTLDQLNVDSLRDSGWIFVGPPSGEPWWYFYTLYQFNLVHWDAVASCFPAMLALTFFGVLHVPINVPALALNIGEDNADLDVELKLHGYSNLISGMLGSIQNYLVYANSVFFMRSGGDSRLAGFMLAGLTFCVMIAGPALIGFIPVMMVGCLIFDLGFELLLDAVWVPRRKLKMAEYLTVLAIVLIMGIYDFVVGIGVGVMLAFVSLIFQTASVPAIRATYSGDIVTSTVRRNPSQHHYLQQAGQQISIVKLAGYLFFGTIVSVEEKIRELLDDKAFSARPIRYLIVDMRQVTGLDYSAVEAFNTIGRLIKTKNIELIVSGVDPESQLGRNLRSVGLVGPEGMGAALLPDLNSALESCENELLKTFYASHKAMSLLHEQQTESTPRLVPPLAGPSRNDLLDMPQNSPRRALLQQAAQVSLTQTQDHVKPKKWVAFKEPLRLMLRIFNGISDKNEDFWFRALPYFVKREHHSGERLYERGEPADGFYLVENGIIRVEYDLPQGFLSECIVAGTTCGELPFFSETPRTATAVVERDCTIWILEKSSWEKMQKNDADVARELLRISLKLTSERMSSITAYILTTANIRAILGGTHKVRKSQVSPGPSPRRRTLSSSSHRSSRLSNLGRPLSTSHTPGQEQPTTVLAAISAVRESMFTSLSLESHAARTMPSTQIARVLAFQRRAAPIVNTSHVRHVLPDATAAIRQIAEALATGTVRRIIVTRSRRWEGLVCLADLEALVRGEQLLGDKTTPPVTEDTANSFLVWVRSGDTCGGLTRSQEDDLVRAGFLAAPTIREWTRHSGTASWNPQDQQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2M8</accession>
    <name>A0ABR3Z2M8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003697</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Necrosis inducing protein (NPP1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000092">
        <property type="protein sequence ID" value="KAL1894315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008701">
        <property type="entry name" value="NPP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657:SF8">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05630">
        <property type="entry name" value="NPP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029958">
        <property type="entry name" value="Necrosis-inducing_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045597545" evidence="3">
        <location>
            <begin position="19"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="259" mass="27890" checksum="CDA30B8296FE5D7D" modified="2025-10-08" version="1">MRFSVSAFTLLSAGLAMAAPAPASAPGGSSIQLDRRADTSNITEISHDAVIGFSEKVPAMSLGSLYLKYKPYLHRYNGCVPFPAVNAAGEVGGGLSPTGSPSGLCTQSTGQVYVRGAWYGSQYGIMYSWYMPKDEPSTGFGHRHDWENAIIWVDSPDVTSPTIVGLSTSAHGGYATIKSDFSSHFNGNSAFIEYISTWPINHQLVISTTQGLMQPLIAYESLTYQARYTLENWDFGSANVPFKEANMASNLEKAWAASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3B4</accession>
    <name>A0ABR3Z3B4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_003405</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000079">
        <property type="protein sequence ID" value="KAL1895131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF3">
        <property type="entry name" value="HALOTOLERANCE PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="19"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="100"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="107"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="271" mass="30027" checksum="67E9EEB9622B1EAD" modified="2025-10-08" version="1" fragment="single">MSPSDKPKERPAQKRSPMSCERCKSRKTKCVDPLPGPCQLCVSTGSVCRVDMSRRRQRPYYQVSEEQFRYMTKALNHVMPNMTLDLPSLRSFVSTINDDSCHDRPETASSKSVSPATSISSDGTRPSILTSETGPIPNTVVFLDEIDKIQGRASWLRVDSAGNHRYVGGEGTYAFHSAVQFAKARQPSSSIDPDLLSTGTAQSTVPSVNMPPTASVSTPRRIYLPRRDLCNKSVTRFFLDIHSVYWLFAVESFEASLDSLYSGDMRSATPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4A4</accession>
    <name>A0ABR3Z4A4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003374</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000078">
        <property type="protein sequence ID" value="KAL1895145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37919:SF2">
        <property type="entry name" value="EXPERA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37919">
        <property type="entry name" value="PROTEIN CBG05606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="164" mass="17588" checksum="57F4B910A0468FD8" modified="2025-10-08" version="1">MVTTRSSTRGASVPPADIAKPPTRARASKAAHAFTHTPTRLTLAWLAISCAVVTWDFTYVFLRPHSMPGGALHAFWAPYALYGEIDHVYGRLAFDAGEGFGPAQSAMNVVETLMYLVYLAAVHRGSGKLSGQCGKVVLLVAFSAAVMTLSKTVLYCKLIDLLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4D6</accession>
    <name>A0ABR3Z4D6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sialidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000079">
        <property type="protein sequence ID" value="KAL1895121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="491"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="508"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="615" mass="66056" checksum="AA4E579396CB2CE6" modified="2025-10-08" version="1">MSPRHARSNSHCSIYSTASAVSNYSAIASAEDSCAGTALNSASPIVKKQHLRQLSRQEAPATHQHGPLLLPKIRSQDQERPLDLDLDLGMDMDLGVNLPSSSRSLSSHGQQRAQSMPFSGVQKRRYVRKTSTSPRVFSTSQLGYMENALNSAAGPATTNLAVGHTDMAAMGTTASVVAPIIVTPDLSTDLSMLTADDTQDLDLGINPIAFQSRSLGFPSMSEYKFPSAQSYSLHGGCTTTSEPSTRGHSPDYSIPSVSPPTTTLSSYLTAPNPAASLVRTLSFPLRDPHTKHFWWDVRQIRPWTDFTASTIRNLPGADTVLNYPIAQSLLPTTSSATRHPESESSLHAIYANTYLPKLNAALALSSSNPLKLSVPSRPSANMSPNELVYTASAIHGPPSPEQLFGGKPRARVVGLVRAFDRFNTAQRVDGNIKRVEYLRGLAALHHAMREHGTRYGFIITEIELVVVRNGPETTPNFGFLEVVSVPLNAAASQSRPETADGKTVENDTTASASTSTSASASGVNVDTDKLSACLALWGLCMLAGDDPMPGHAHWKSDIGAPAEGTRCKALARDSWMPPPQLAEKREAKRARGWVLPEDPIGRKELGKRGVKYGGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4W9</accession>
    <name>A0ABR3Z4W9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">3-dehydrosphinganine reductase</fullName>
            <ecNumber evidence="9">1.1.1.102</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">TSC10_1</name>
        <name evidence="13" type="ORF">Cpir12675_003324</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the reduction of 3'-oxosphinganine (3-ketodihydrosphingosine/KDS) to sphinganine (dihydrosphingosine/DHS), the second step of de novo sphingolipid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>sphinganine + NADP(+) = 3-oxosphinganine + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22640"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57817"/>
            <dbReference type="ChEBI" id="CHEBI:58299"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.102"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:22642"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.102" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000076">
        <property type="protein sequence ID" value="KAL1895307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08939">
        <property type="entry name" value="KDSR-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045022">
        <property type="entry name" value="KDSR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43550">
        <property type="entry name" value="3-KETODIHYDROSPHINGOSINE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43550:SF3">
        <property type="entry name" value="3-KETODIHYDROSPHINGOSINE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="304"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1895307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="350" mass="38440" checksum="5124BCEE10AEFD5E" modified="2025-10-08" version="1">MEPLSPFWIAIPPVISFLCAYAMGIFSKNQFPVDGKTILITGGSEGMGLSVAKQLAAKGANIAIVARRKDKLEEALVQIKAAARNPDRQRFHFVVADVAIPDYSKTVLANVQVWNNNSSPDIVWCIAGVSTPGLWIEQDLADTKRQMDINFYGQAEMAHSILREWTSSENPADCNPASDAKHIILTASVVAFCSIVGYGSYAPSKFAIRGLADALAQELMLYPQNMKVHVVYPGTILSPGLERENEVKPEVTHLLEASDPKQTPDQVAAKSIQGLEHGDFFVTVAFLGSLMKWGMLGGSLRNSWLIDTIMAMLVPIVWIFVQADLTGTVKKYARKHGHPRYWETKTGPKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z566</accession>
    <name>A0ABR3Z566_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">LETM1 domain-containing protein ylh47</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">YLH47</name>
        <name evidence="11" type="ORF">Cpir12675_003109</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000068">
        <property type="protein sequence ID" value="KAL1895776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033122">
        <property type="entry name" value="LETM1-like_RBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044202">
        <property type="entry name" value="LETM1/MDM38-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14009">
        <property type="entry name" value="LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14009:SF1">
        <property type="entry name" value="MITOCHONDRIAL PROTON_CALCIUM EXCHANGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07766">
        <property type="entry name" value="LETM1_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51758">
        <property type="entry name" value="LETM1_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="203"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Letm1 RBD" evidence="10">
        <location>
            <begin position="249"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="475"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="529"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1895776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="548" mass="60518" checksum="0C7089050B911896" modified="2025-10-08" version="1">MSATAAVARRTVTLAGRSLSRSQFAAANSLLIRNARTIPLFTPAVSLLSSRYVSTEPHRPGMPPGPPPGFNAEVARKPLPRDVAFKKEPSATSKSVQSELANKTIAATAKLSQQTSSQQMSKDGNASLSTPKTDAEIAAAKEEQEKNMTLWEKIKHEANHYWDGSKLLAAEVKISTRLALKMMAGYELTRRENRQLRRTVQDVARLVPFSVFVIVPFAELLLPFALKLFPGMLPSTFEGDKSKAAKASILRATRKEVSTFLQSTLQETGIPLAIASSQKEEFRRFFIKLRSTGEKPEDSAVIRICQTFKDDLTLDNLSRPQLVSMCRYMNLGTLGNDGMLRYQVRHRMRQIKRDDRAISFEGIDNLTPGEVQTACASRGIRTHGVSPARMRADLQTWLNLRLKEGVPSTLLVLSNAYMYSGDMTSQVDALMNVLSSIPEELYHEIELEVHNAEGAATNKQRLEVLKEQQELIEDEAKQDEVHETTGMAAPRDNANIDEREERLAAQPDVLEAKVAGEVAAAEAETIKAVKGAPTSETDAAVESKTKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5L4</accession>
    <name>A0ABR3Z5L4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7029 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003493</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000084">
        <property type="protein sequence ID" value="KAL1894799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054293">
        <property type="entry name" value="DUF7029"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22974">
        <property type="entry name" value="DUF7029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7029" evidence="2">
        <location>
            <begin position="91"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="444"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="474"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="531" mass="57377" checksum="3C1DE4CCAA44C430" modified="2025-10-08" version="1">MSIALKIHDPSHSPPLLVLGPVLYPGLDRASKSHLVPVSSHNISYRPLPLQLPREVLDPDRPPVAARSFSPPLDPLSATQSRGSANSTFFFKHPAVVLENIASILAVVCFASKDSLTVTFTTEDAMLEALREWERHSNFLLVTNHGNHCDSSTEQGYFLATRVTQSPIGSSLVLVARKSDMKSVVSNIHMSFSSARTPNPGGFKQGRRDVGDANTIAQRPVISPSMEMTYNQELPPNTTLLAWPAFIHVVSNTAYITSTLEFSGYLDYNMDNMTVNQLYVNVDCNYEAAFKVTASVLQEFQKTTDLALIQANNIPEINIPNVVRIAPVLAFAVKADMAAKSAFEASSAYKVQIPDGNVHLDILSPENNGLRGFAPEFSVQAHATEDVPAHFNISTILDVGLSLEFGNLIAFDCGFNITTKVNNVIGISAKQGLQLGDGIDIGGEPTATSSTSSSADVSMVSTTATPAQLEPESETSTSSTNISASANCGQNKVKLYSEFMVDFAMNNLSLFRETKVLLDVCEDLWEGEGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6F7</accession>
    <name>A0ABR3Z6F7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-synthesizing GTPase</fullName>
            <ecNumber evidence="2">3.6.5.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">GCD11</name>
        <name evidence="11" type="ORF">Cpir12675_002913</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.3" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000062">
        <property type="protein sequence ID" value="KAL1896206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01888">
        <property type="entry name" value="eIF2_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03688">
        <property type="entry name" value="eIF2_gamma_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15490">
        <property type="entry name" value="eIF2_gamma_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050543">
        <property type="entry name" value="eIF2G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015256">
        <property type="entry name" value="eIF2g_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044127">
        <property type="entry name" value="eIF2g_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044128">
        <property type="entry name" value="eIF2g_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003077">
        <property type="entry name" value="PRK04000.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42854">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42854:SF3">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09173">
        <property type="entry name" value="eIF2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 11" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="10">
        <location>
            <begin position="77"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1896206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="507" mass="54994" checksum="1F22BC6DC4520D93" modified="2025-10-08" version="1">MSSVEEPKIDEHVDNNVNVESDHESADEQPLKPALKKTNPATGTSTEPKPYLPPQTEPKDLDLKTLSPLTPEIIARQATINIGTIGHVAHGKSTVVKAISGVQTVRFKNELIRNITIKLGYANAKIYKCDNDACPRPGCYRSYKSDKEVDPPCEREGCEGTYRLFRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLDKIIILQNKVDLMREEAAKQHHESIQKFIRGTVAGKSPVIPISAQLKFNIDAVNEAIVNTIPIPPRDFTQDPHMIVIRSFDVNKPGAGIDELKGGVAGGSILHGVLKLDDEIEIRPGIVTRDEKGALKCTPIFSRIVSLNSETNDLKYAVPGGLIGVGTRIDPTLCRADRLVGFVLGLKGRLPEIYSEIEVNFFLLRRLLGVRTADGKQAKVAKLAKNEVIMVNIGSTSTGAKVAAIKNDAAKLILTSPACTNIGEKVALSRRIEKHWRLIGWATIAAGVTLAPSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z6Y7</accession>
    <name>A0ABR3Z6Y7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">UFD4</name>
        <name evidence="9" type="ORF">Cpir12675_002940</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPL family. K-HECT subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000063">
        <property type="protein sequence ID" value="KAL1896027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045322">
        <property type="entry name" value="HECTD1/TRIP12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057948">
        <property type="entry name" value="TPR_TRIP12_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45670:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HECTD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45670">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25579">
        <property type="entry name" value="TPR_TRIP12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="8">
        <location>
            <begin position="1632"/>
            <end position="1989"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="161"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="845"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1212"/>
            <end position="1301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1333"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1430"/>
            <end position="1450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="47"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="62"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="77"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="96"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="161"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="211"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="246"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="274"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="315"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="340"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="864"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="902"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="937"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1218"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1245"/>
            <end position="1276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1284"/>
            <end position="1299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1336"/>
            <end position="1345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1441"/>
            <end position="1450"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="1956"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1896027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1989" mass="218444" checksum="1EDCF55185F9FDFA" modified="2025-10-08" version="1">MADPISHNDDNELGLYSQQQSRPHSGYHSQFPSHGQPATPTGPHTIPPHSLLSSPSPLNPSTAATTDLNRILNTHNTGRPTGSSTSSRLPVLSPITSPLLTTRVTRSSSAREAASRAAAAQPSSDPSLTSPNSTTNDITITANITSTPTSNAATTAGELQQLSHSAHQPLSSARKRKSLNPDASVKPLLSSPTASRQNKRRRATADGPHQISTSNIPSSPSSRFHQRPSRSAAMASQDRDHEDDVTMSSPTATPSRRYSRNKNKRTARDLQERTSTSTSPSSQPPSKEAAVSSDQDTAMTGIDGSARSQSPDEHDRDDDSEEHEEGEDEENHHRHHRYDDDDEEEDDDDDPFSEYGNASLSQTLRALTGMMASGMSSRIREIINSLRQGEEIMQHTALQELSQILLVSSEDNLQSQFSPDALVHELVKLMQPESSPEIMLLACRCLANLMEAMPGSVGNVVYGGAVPVLCSKLLEISFIDVAEQSLSTLEKISQEYPAVIVREGGLTACLSYLDFFATSTQRTAVTTAANCCRNIPQDSFSVVRDCMPKLLDVLSSSDQRVVEQASLCVSGIVESFKYDPDKLEELVTVDLLRAVLRLLVPGTTNLISSSIHTQFLRVLSHTARASPLLSAELFKLNIVETLYQVLTGISPPADTDGVAAKLDGIVIMQALIHRPREQIMEALNVICELLPKKSSESRDGFVQYFNLSISGAADAAKNEKRIKLLKECQLAVRRFALILFPTLTDAFASTVNLNVRQRVMMAHIKMLSNLDKQILLETLSSVSYASFLASIFSQQDHHTLVRMALESSELLLSRLGDVYRYQLYREGVIAEITKLANTNVEVEVEEADVTGPAPQACSDHSDASDDEFLPAEEEFDEEAKSQADGQEGEASGPEVASSGNETSEEEDHENESEAEGSDNDIDHDHEENIDIDDDGLSSHSSRESSASLNLNDDLVSRAEIRSLAKEFLKNHETEKQSKQMKKKAAKILNSLADLSTELEAFFLGRNVADSSPEAGKELFVRLANYFDGDVLESVTSAEILASGLIKVLLNIFSNPDEILARDSQATFLEIFMDNTLNPKSKTSSTPFSCMVHKLQDVLSRSEHFDVVTVQNGLFEGGRSSSASFLAKQIKLKLVADDDSNVPKPYRNMMVSIHAIASFQSLADYLRPRIEMSNLGDLSGRYATLTQALAAIKNSGTLTSAEANQLVARLGEAMNPGFPSNPLPPPPGSIPKRHRLENSGHAPSTPEITSGSKGKARQNSQRSTDSLQASATSPQHSQESRDPFDCEEENHEPDDGDDTVSETLARNMDNPALNEETPDRSHIDLEFSLLSGVLDGSRTSPGANSHPQDEEISSGGASTNPPNDDAGLAQLAAATVVPPESSEWHIEFLVDGKPITNDVTVFRAIYNINSNEDAHGHNVWSTVHQIKYRKVSGPAPTESPPARSSSVDIHSDNSGTVAIPTSLTQHPVTASVLRLLRILHDLNANIEDVMTDNTNVLRLNVEPLTHFVNTKLTAKLNRQLEEPLIVASNCLPSWVEDLARCYPFLFPFETRHLFVQSTSFGYARSMARWQNSQPSDDRRSRDERQFLGRLQRQKVRIGRAKIFESALKVMNLYGAGQSILEVEYFEEVGTGLGPTLEFYATTSREFAKKKLKLWRETDSPDDEYVNGSTGLFPRPMSDAEADTPNGRRILHMFAMLGKFVARSMLDSRLIDINFNPIFFRIGDGPMTAGVRPSLGAVKSVDPDLARSLKLIKKFAMAKKEIEEDATRSAAQKVDDLEKITINGCHIDDLCLDFTLPGFPDVELIPNGDQARVTIDNVENYLDCMIHMTLGSGVRRQIDSFRVGFTTVFPYSALNAFTPDELVSLFGRVDEDWSLETLMDSIKADHGFNMDSRSIRNLLQLMSNLNVSERRDFLQFTTGSPKLPIGGFKALKPMFTVVCRPSEAPNTPDDYLPSVMTCVNYLKLPDYSDMETMRKQLMTAIKEGQGAFHLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z738</accession>
    <name>A0ABR3Z738_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein phosphatase PP2A regulatory subunit B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CDC55</name>
        <name evidence="6" type="ORF">Cpir12675_002772</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the phosphatase 2A regulatory subunit B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000057">
        <property type="protein sequence ID" value="KAL1896483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000009">
        <property type="entry name" value="PP2A_PR55"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018067">
        <property type="entry name" value="PP2A_PR55_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11871">
        <property type="entry name" value="PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037309">
        <property type="entry name" value="PP2A_PR55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00600">
        <property type="entry name" value="PP2APR55"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01024">
        <property type="entry name" value="PR55_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="405"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="408"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU331113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1896483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="471" mass="53521" checksum="AFF6B395A4CF054C" modified="2025-10-08" version="1">MGESEVTGPTWKFTQCFGDKGDIEDITEADIISTVEFDHTGNYLATGDKGGRVVLFERNETKKTCEYKFHTEFQSHEPEFDYLKSLEIEEKINKIKWCRRQNPSHYLLSTNDKTIKLWKVFEKSLKVVAENNLSSEPTPAGMGAGAPVARPSAFKHATDLKLPRLTHHDTVVAAVPRRTYANAHAYHINSISVNTDGETFISSDDLRINLWNLNIQDQSFNIVDIKPANMEELTEVITAAEFHPISCNWLMYASSKGTIKLSDMRERALCDQHAKMFEQEDDPSARSFFSEIISSISDVRFSNDGRYILSRDYLTVKIWDINMERQPIKTIPIHEHLRPRLCDTYENDSIFDKFEVVFSGDNKNVMTGSYNNNFMIYPTDPEQETEVVLQADKCAFKAKKIGVPTPINSSSSPNGKKSSSRANSPAGQRMRKETDADQIDFNKKILHMSWHPFEDSIAIAATNNLFVFSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7T4</accession>
    <name>A0ABR3Z7T4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_002739</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000056">
        <property type="protein sequence ID" value="KAL1896643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047208313" evidence="3">
        <location>
            <begin position="22"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="472" mass="50067" checksum="821F13C048F68AD0" modified="2025-10-08" version="1">MLPALLLTTLYLFLFYTPVAALQVTPGSPCAQHCIDNTADDPFSAASSSTTASDIVCTDAAFGTEGTGARFRECVECLQKSGKVNGTESDLHWLLYNLRFALSTCLYNPDVLPESQRINSPCLIPSACQPLEPAITQGDINASTTAAPTSMYEYCAAGSGDLLEETWEEPCVSCLQSTTDQYYLSNFLSVLKGACAQRPEAGTLLGIAGDIFSRDAINTTVATEDSSTSTGGDSGGMNTPIIVGISVGASLVLVGGIGLFWVYFQRKKHFERTSAAGAASATAHLNHSEIWATSISKTVGSESIPMYSTSQSAGSAYGMGTKERASTSMDTKIWIGADGRVGHEYYDLYENLPPGFAFGYARSDPGVLVPHPAYIPGCSSRTTSPGSLPSQSPTQTLSQSPSQSSVSSGTFLVPSNQDKRPQVPALIMPSSSQYRQKKYLPPQITIQSASPITEEDESHSLAEKGANRPKIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7T8</accession>
    <name>A0ABR3Z7T8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 11">Chitin synthase</fullName>
            <ecNumber evidence="2 11">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">CHS2_2</name>
        <name evidence="14" type="ORF">Cpir12675_002824</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine = [(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9595"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="EC" id="2.4.1.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:16638"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cell membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the chitin synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2 11"/>
    <dbReference type="EMBL" id="JAWDJO010000059">
        <property type="protein sequence ID" value="KAL1896420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04190">
        <property type="entry name" value="Chitin_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013616">
        <property type="entry name" value="Chitin_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF9">
        <property type="entry name" value="CHITIN SYNTHASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01644">
        <property type="entry name" value="Chitin_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08407">
        <property type="entry name" value="Chitin_synth_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4 11 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="573"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="617"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="651"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="696"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="826"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="876"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin synthase N-terminal" evidence="13">
        <location>
            <begin position="158"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="55"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="757"/>
            <end position="783"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU366040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1896420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="904" mass="103030" checksum="3147EAEE49554E62" modified="2025-10-08" version="1">MDSRGPHPRQTPSPGHPHQQGYQLEEHPYGQQHDPYGNNDIYAQQQHHDPYVQQEPAHMPMGHYGSGESVQMNTPRPIDPFEDQSQHPDYSINPEQHHDAYYNQPYDSAPPDPYNQYDDHQPMLNDEQRTNYQDMPVPTATPAPSMGGGGGGGLKRWKTVKQVLLYRGNLVLDCPVPPKLLRQLPHGERDEFTHMRYSAATCDPSDFHDDNFTLRQKLFTKPRHTELFIVVTMYNEDEILFARTMIGVFKNVEYMCTRKNSKTWGPDAWKKIVVCVVNDGRSKINPRTRAVLAGLGVYQEGIAKQTVNNKDVTAHIYEYTTQVGVQIKNDVVQLVPKQQPVQILFCLKEKNQKKINSHRWFFQAFGRVLEPNICVLLDAGTRPGGRSIYDLWKAFDLEPMCAGACGEIKAMLGKGGRKLLNPLVATQNFEYKMSSILDKPLESAFGFISVLPGAFSAYRYVALQNDKNGHGPLEKYFDGEKLHGAGAGIFTANMYLAEDRILCFELVTKRNCHWILQYVKSATGETDVPETIQELVLQRRRWLNGSFFAAIYSIAHFYDFFRSDHSFFRKFMFFVEFVFNTINMIFSWFALGNFFLVFKILTTSLEADNLLGNVGQYLGIVFLWLYGISLMTCFVLAMGNRPAGSGMFYGVMVYFWAIIMIYLMFAAIYISVQAILTDVRDSNGFSPQDLIKNPVFYNLIISVMATWGVWWLASIIMFDPWHMITSFAQYMLMTPTFTNVLNVYAFCNTHDVSWGTKGDDKPDQLPSVSTKDGQGKTDLPDEGDLNAQYERELGVFGTKYVEQKTTPTAAQLDEKQMDYYRAVRSITVMCWMITNFALVALVLSTAGLEKINPDPSATQADQDEEENKRTNLYMSIILWSVAGLSAFKFIGAMWFLIVRMFRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z809</accession>
    <name>A0ABR3Z809_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Centromere protein Scm3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002666</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000054">
        <property type="protein sequence ID" value="KAL1896718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018465">
        <property type="entry name" value="Scm3/HJURP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15992">
        <property type="entry name" value="HOLLIDAY JUNCTION RECOGNITION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15992:SF5">
        <property type="entry name" value="HOLLIDAY JUNCTION RECOGNITION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10384">
        <property type="entry name" value="Scm3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="407"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="536"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="626"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="659"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="723"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="796"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="865"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1046"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1126"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="555"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="631"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="796"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="808"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="925"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="947"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1140"/>
            <end position="1157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1207" mass="133326" checksum="BCCF297BE7ADA0AD" modified="2025-10-08" version="1">MEHLLSVNPASLHSSSRTDSSSENEEDELMYEPETASELRDPGTKLAKARDHAAMRLKSTFEHIFEKYERDFTGIGDEIDLRTGEIVVDNGHLTSMRHERDTGDGLVNDLPSDKLIMSINVSNEEDICLEDLDALDAVLEDGNKKYNATRQDPYDDDNDDYDEADEQRILNRAQNPRHETTTSTTPQAKSLILRSRNQAIVPAYSQTRKLSTLALRQTPHLSASPLIFGSAHGIWGPDTPQDPLWKVPEINISGFKSSFAANLFQAENQRRYILPVHTGQESIWAPAPREKLEWATPPRKLIGASKVPRETDAYKLSGTPASQDETIDHCNDDDLPLSITRRRRSFKPSVAIATLPVRARPQTITPNLDFESSAPTKRASSKFKRSHRPASSPCRQAETLMCRKRKTRHNCTTPSSKVEGVREKSSPLYLPNSSLPDTTIVTVPTNKPSKFSSFPTTKKIEATTPSHRRGQKVVIELPKTPSAAKSLYIEIPDDHCTLYQDQPKSSLLSPQGASSSVARRILHRNTTPTLAITYSDWESRVPTPPERIIPDSEEPSSSISKSTIADSTAPSSLDSELISPTDHATSPEADFEVIENDSYIDEDYKTLSEDSDKLTQQEEVLAVETLEDSTEYSSNEELISNKSLLEDENDDTVIVHPISSHNSDLEDEALDTNSRDENSTSTRSHCSLVRGNILEDKNGISGKTNSYDSGNDSEDTVIIHRQSPCTTDSPANSPNPGYNHHSLSINQDENPALIDDMPTASFSQKPTLQGTRLFLRPSISPSYNFSDDEDGFVISAKPSIAKSPSPTKKPKNVPRRRASALGKSSPIARPSVSYGQSGLSKNLIASGDSALANSLQLASPIGTQSGIIDVHPKTNDTEPNSRLSHKKRKRTVIDDDSDEEPGPSKIDVKEWFKPQPATPSDKVPWKRVRPSPRTYTRKGQRSRFGSKVTSFSSPVNKPSVRSTEQTSISRMFSKPAVPTPVMEETEESELYIPDIAKSPSIEEVAKDNDMSDESYDHLRSTSDVLEIPSSPSRLPRIRPPYETITIQPHNSPHDGDTLESLPPTTPRRAEHAPLTPSASKRSFARRAAASMALDPDEDELSVNLRVLMYPNPHLYASGFRKRTFTATVPETPSSKRRRPPTSSRSSFTGHGTGSTTVKKRVSAASLARLAPPSPTPVVARTPGGTLRRCGEDGFRCHREFCFSCVSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8G5</accession>
    <name>A0ABR3Z8G5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Exocyst complex component SEC15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SEC15</name>
        <name evidence="8" type="ORF">Cpir12675_002794</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the SEC15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000058">
        <property type="protein sequence ID" value="KAL1896457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.670">
        <property type="entry name" value="Dsl1p vesicle tethering complex, Tip20p subunit, domain D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.30">
        <property type="entry name" value="Exocyst complex subunit Sec15 C-terminal domain, N-terminal subdomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007225">
        <property type="entry name" value="EXOC6/Sec15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046361">
        <property type="entry name" value="EXOC6/Sec15_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042045">
        <property type="entry name" value="EXOC6/Sec15_C_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048359">
        <property type="entry name" value="EXOC6_Sec15_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042044">
        <property type="entry name" value="EXOC6PINT-1/Sec15/Tip20_C_dom2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12702:SF0">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12702">
        <property type="entry name" value="SEC15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20651">
        <property type="entry name" value="EXOC6_Sec15_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04091">
        <property type="entry name" value="Sec15_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF025007">
        <property type="entry name" value="Sec15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 5" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component EXOC6/Sec15 N-terminal" evidence="7">
        <location>
            <begin position="51"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Exocyst complex subunit EXOC6/Sec15 C-terminal" evidence="6">
        <location>
            <begin position="407"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="Exocyst complex subunit EXOC6/Sec15 C-terminal" evidence="6">
        <location>
            <begin position="469"/>
            <end position="712"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR025007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1896457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="728" mass="82697" checksum="50629C7CDC3B2EC9" modified="2025-10-08" version="1">MSRRTRAYDDYQSAVEGIILPPAESDFIDQLIPILKDAANTGRTSSLMQSLSSYANGKEAEIEQIGLTQHGEFLASVNQLQQVRETTVFLTTEIMGLNESIQSSTEKLAAQKQVLVNTRATRQNLGDASSALQESLRILHAVNNAHELIRKKKYYAALKSLDDLQNEHLIPTIQNKYATQQRLADVIQKSIPSSQRIISDAVMTDLNTWLFRIRETSQFLGEVAFYHTELRRERQRERVKQDPYISKFKLNSAIELVCDDGEEFDVLDNDELQIDFTPLFECLHIHESLGQSERFRAEYSATRRQQKDLLLPGSIDLLSDGEMSLSALLEGIAGFAIIEKATLQRVPQLRSLVDVEELWDSMCQTSMSLTSRALNDVSDAEGLLKIKGYIAIFIQTMEGWGYSVSMLDGFLLTLFQKYSDLLKHRFSEDFQEIVSTDDYMPMAIQSAEEYEKVVNVSWFNQEKPVSELTLIDETLRKALDELLVEKVCRSLVDKLASQYLSQIVQILINLEHFEIACQELEQLLIRARSSTSAGGPVSLRATTEFRNNKKTAEKRIFEVVNSKIDDLVDTAEYNWMSSTPPTETSNYMQTLTTYLSNIMNSTLLGLPREIKELIYFDALSHAANKILALPLSQDVKYINSCGVAALAKDVHYLTDFVDSLENGAMLRENLDELQQTINLMQSDNHDEFFDISTRNKKYGRVDPLNGPILLEKYSPFLAVFDLEILMTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8Y2</accession>
    <name>A0ABR3Z8Y2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">ER lumen protein-retaining receptor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Cpir12675_002655</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERD2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000054">
        <property type="protein sequence ID" value="KAL1896707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000133">
        <property type="entry name" value="ER_ret_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10585">
        <property type="entry name" value="ER LUMEN PROTEIN RETAINING RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00810">
        <property type="entry name" value="ER_lumen_recept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00660">
        <property type="entry name" value="ERLUMENR"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="261"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="316"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1896707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="352" mass="39822" checksum="8F165A94B98C7AE3" modified="2025-10-08" version="1">MAVFNARVSLISQIFYALVFLTRYTDLFQETYLWNTIFKFFYIFSSLYIVAIMQFHFPRTRELELSWKLGGIIFVGSLGLTPFIYWFSNHPSGHFFTTSLYDFSLILESVCILPQLLLLRQTSIPTVINSFYLLALGAYRALYVLNWCVRSLDKEDYPLNHVSVFFGIVQTVLYADFFYVYYSRQRVKLRNGSIIDSEDMDRGWIINRLFGHNIEPLAHNDEENPRSLRRIGDLSVNAGSHSQSASASRAKWGSRGISISADDDTLEQAEGSTRDHLSRNVDPDAKMKDPDELALALDDDSDNEGTSNGLGRDASSDDESDDESDDDTSPAAAKKPLTGGSGAGVRNDEWRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z908</accession>
    <name>A0ABR3Z908_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002975</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000064">
        <property type="protein sequence ID" value="KAL1895999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046932982" evidence="2">
        <location>
            <begin position="18"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="170"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="270" mass="26275" checksum="0E5B5FCAAF29BECD" modified="2025-10-08" version="1">MRSSAPALLAFAAATLAKTDLAGCSSYTTTMIDAEGTPYASVVWYVPGSLEVCSIVDCGGGRVPANQALGCPGYTGSAVVSTQFLTALPTDASIVPTSAATEISQATGTPTAIISASESTINTATAISSLTATATSMDTSMATDTAASTALASTTGSGTLTVSTTDSVTTTSLPFTTTTSPTTSSSSTFSTTSTSTTRSSTSTTSSTTSRTTTLSTSMTSTTTRSTTSRSATSSASASSTSDPESGAAGTTNGIMSAIAAGVAAAAVILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9B4</accession>
    <name>A0ABR3Z9B4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">T-complex protein 1 subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">CCT-alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">cct1</name>
        <name evidence="12" type="ORF">Cpir12675_002615</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000053">
        <property type="protein sequence ID" value="KAL1896894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03335">
        <property type="entry name" value="TCP1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012715">
        <property type="entry name" value="Chap_CCT_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02340">
        <property type="entry name" value="chap_CCT_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="478"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1896894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="565" mass="61104" checksum="048C321E771658FC" modified="2025-10-08" version="1">MGSLFEQSGNGTLFLGGQKISGSDIRDQNVAATQAIANVVKSSFGPSGLDKMMVDDIGDVTVTNDGATILSLLDVEHPAGKILVELAHQQDKEVGDGTTSVVLIAAELLRRANELMKNRIHPTTIITGYRLAIREAVKYMNENISMKVESLGREPLLSIAKTSMSSKIIGADGDFFASMAVDAMMAVKTVTSKNEVKAPVKAVNILKAHGKGTKESILVKGYALNCTVASQAMVTRIQDAKIAVLDMNLQKERMKLGVQITIDDPQQLEQIRARESGMVMERVEMILKAGANVILTTKGIDDLVMKMFIERGAMAVRRCKKEDLRRIAKATGATLLSTLSDLNGDEKFETSYLGYAEEVAQERISDDECIMIKGTKAHSSASVILRGPNDFQLDEMERSIHDSLCAVKRALESGAVVPGGGAVETALHIYLEEFAGTVGSREQLAIGEFAQALLVIPKTLAINAAKDSSELVAQLRSRHAVSQRAPEGDSQDDEKTAARKKAYKNYGLDLAQGKVVDSVKSGVLEPSMSKIRQFKSAVEACISIMRIDTLIKLDPEMQQDDGHGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9F5</accession>
    <name>A0ABR3Z9F5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_002648</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000054">
        <property type="protein sequence ID" value="KAL1896700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1896700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="204" mass="22615" checksum="DD1F56E07379BCF0" modified="2025-10-08" version="1">MNDFLNEHPRETTILRVQTVSIVHLKSFQSSFQKFMNSVNQQYTVHRIYSPDTDRITTAPALGEIRGKILMLQDFKTSSPGRYGLPWSSDTVSIYSTKLAVSTLFLNLTWADVKSHLNEAPLTGSGMNKLIGEYLINNDGDCYGIIVMMDFPGQYLGQQIVKLNDKYLSLDIPGVSHDRADASVVGEVGSSSTVRDDEASSVDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA31</accession>
    <name>A0ABR3ZA31_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Plasma membrane sulfite pump involved in sulfite metabolism</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SSU1_2</name>
        <name evidence="9" type="ORF">Cpir12675_002306</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000044">
        <property type="protein sequence ID" value="KAL1897518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09318">
        <property type="entry name" value="TDT_SSU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.150">
        <property type="entry name" value="Voltage-dependent anion channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004695">
        <property type="entry name" value="SLAC1/Mae1/Ssu1/TehA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051629">
        <property type="entry name" value="Sulfite_efflux_TDT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038665">
        <property type="entry name" value="Voltage-dep_anion_channel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31686">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31686:SF1">
        <property type="entry name" value="SULFITE EFFLUX PUMP SSU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03595">
        <property type="entry name" value="SLAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="104"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="179"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="249"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="284"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="335"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="398"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1897518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="448" mass="49617" checksum="11A1DC0D64AE5D3A" modified="2025-10-08" version="1">MGPLDVPMPISSHDVETNGGSYYASNSETSVDKSHIHVDMNIDIRMQPTATGATATPETPSPELPLLPRWRRMIRNFTPSWFAVTMGTGIVSILLYSLPYRCFFTTALSYCFFALNVVMFVVFTIISILRYMMYHDCWRAMVHHPVQSLFLGCFPMGLSTIINMSTISLSATWGAPLLFIVWILWWLNVVSSLATCLFVPWMVIYRHKPGLNTITAALILPIVATVVCAASGGLVALHLPDAGNAQLTIIVSYILWGLGEYFCAIIICLYFHRLTMHSLPPRDFIVSVFLPIGALGNGGFGIINLGLASLKTFPKTGLLAENIGGEGSSLVAGHVLYVIGILIGLCCWGFGMVLLSFALISIFTTKRFPFNMGWWGFTFPMGVLATCTGLLAQQLDSIFFRIMTLLLSVAVIILWFIVAIKTVLLARRDLVAESFPEYPLWKKEFQPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAQ7</accession>
    <name>A0ABR3ZAQ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mannitol-1-phosphate 5-dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_002571</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the NAD(H)-dependent interconversion of D-fructose 6-phosphate and D-mannitol 1-phosphate in the mannitol metabolic pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-mannitol 1-phosphate + NAD(+) = beta-D-fructose 6-phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19661"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:61381"/>
            <dbReference type="EC" id="1.1.1.17"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mannitol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.17" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000052">
        <property type="protein sequence ID" value="KAL1896923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00196">
        <property type="entry name" value="Mannitol_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023028">
        <property type="entry name" value="Mannitol_1_phos_5_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000669">
        <property type="entry name" value="Mannitol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013118">
        <property type="entry name" value="Mannitol_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013131">
        <property type="entry name" value="Mannitol_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002652">
        <property type="entry name" value="PRK02318.2-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30524:SF0">
        <property type="entry name" value="ALTRONATE OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30524">
        <property type="entry name" value="MANNITOL-1-PHOSPHATE 5-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01232">
        <property type="entry name" value="Mannitol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08125">
        <property type="entry name" value="Mannitol_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00084">
        <property type="entry name" value="MTLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mannitol dehydrogenase N-terminal" evidence="9">
        <location>
            <begin position="11"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Mannitol dehydrogenase C-terminal" evidence="10">
        <location>
            <begin position="216"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1896923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="399" mass="44074" checksum="DB0E4DA4471B1E91" modified="2025-10-08" version="1">MSSQSTSAPLKAVHFGAGNIGRGFVACFLRESGYEVVFADVQDALINSLNEHPSYKVIEVGSEGTSEKTITNYRAINSRTHEQDLVNEIATADLVTCSVGPNILRFIAPVIAKGIDKRSSDRAPLAVIACENAIGATDTLASFIRDPKNTPADRLEGHDSRARYANSAIDRIVPAQDTNAGLNVTLEKFYEWVVDRTPFADHSVPPIEGIHWVDNLIPFIERKLFTVNTGHATAAYHGYNRQKATVYDALQDKAIMAEVRRALEHTSQLIIEKHGIDAQAQKDYANKIVMRIGNPHLEDAVERVGRAPLRKLSRKERFVGPAAELAEKGYDVAGLLKAAEMAFRFQSVEGDEESHQLAKIMAEKTPQEVVSEVCGLQTNEKLYPMMVEVVRCVQEDMED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAX5</accession>
    <name>A0ABR3ZAX5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein YIP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_002253</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000041">
        <property type="protein sequence ID" value="KAL1897753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045231">
        <property type="entry name" value="Yip1/4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21236">
        <property type="entry name" value="GOLGI MEMBRANE PROTEIN YIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21236:SF2">
        <property type="entry name" value="PROTEIN YIPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="173"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="192"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="302" mass="31645" checksum="A56C173742E8C8E0" modified="2025-10-08" version="1">MSNYYPTQGSGGQSNYGSQNLQFYPSSYSPAQVSGTPSQAYNSYGGGYGAGTGATSVGVSGRMGEQGGLRTGWLAAFSTEGYDGEPPLLEELGVNFGHIQGKTLAVLNPFARIDQHIMDDSDLAGPILFFLLFGTFLLFSGKVHFGYIYGLALLGSTSLHAILSLMTPSETAASSQPQYHGNSMYPEHQENPSVSGPDDSSSPTLTYARSASVLGYCLLPLVATSLVGIVMPMDTPLGIVMTSAAIMWCTASSSGMFCAVGRMRAMRGLVAYPLALFYVGFGIMGIFSSRGSGSLNRVAGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBQ1</accession>
    <name>A0ABR3ZBQ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UDENN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_002280</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000043">
        <property type="protein sequence ID" value="KAL1897552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001194">
        <property type="entry name" value="cDENN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043153">
        <property type="entry name" value="DENN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051696">
        <property type="entry name" value="DENN_Domain_GEFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037516">
        <property type="entry name" value="Tripartite_DENN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005113">
        <property type="entry name" value="uDENN_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12296:SF31">
        <property type="entry name" value="DENN (AEX-3) DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G11200)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12296">
        <property type="entry name" value="DENN DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02141">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03456">
        <property type="entry name" value="uDENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00799">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00800">
        <property type="entry name" value="uDENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50211">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDENN" evidence="3">
        <location>
            <begin position="87"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="693"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="770"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="557"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="37"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="697"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="786"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="853"/>
            <end position="865"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1897552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="936" mass="105183" checksum="9C112652CF7517C3" modified="2025-10-08" version="1">MPPSLSTHPSFSRPRTGEREGRPMTRDQGDNGLVIPSRTSSLHSRITQPIPSMLNPKLQQRTPKTLTHAYMVCGVGREPSQWVKAPAPTQGKIGHMKGAVGQFWLPEILGSSPRLEQDNEIARALHSAMRACFPHDVEICTGRSQPHCVHHSFVLQQDSSHTLYGICLRVWSRADEKRAETIRDLRKRTETDYFDNPDEIYWIPYCLSFLSRYPLYNLLGDYLRGMWIHWNKATNLFHAEEVSRILSFPAPRLNDLVRIDMKDYALCYQFPSSPTGFQNFAMWPLFSCLSIPNIVGVVEAAISPTRRIIFVSHYPAMLTMAAETIRFCVRIYEWSGLYVPVVHARHAKDLVQEPGPYILGITAECRSLFTAPTDALVVDLDRNFVLTSSPPTALTPGQRHKFVTRLTEALNGDVTPSGVPQHLRSAYGGGKLVPAGQIIVMRGEVESIQDPDWWNQDSIMSVMDHVCEKMGRNTGIKAVFGGSVKKPLMTKVSMRHLNEIVRERNQYSRDAIEAWQDFINLKGRMDTELSKVTKRNNYLVEELESWKQQFLKFQAFAETLTKETQDLKVKIEGHKRENRRLAGLLDQQKDDNSRMSVRLTGTEKQRDDALEALVLQQEIAEELERERKRNKKELAALQHTNITIGRQRDEARRVVLHLRSLISGQRHHMDHIVETLTRPDELLQELEAGYAEDDAAGDVQSSPISDLSSPTSTTSMNSKRYSASSFIDVADRHLKDKTDAIAHIIRNIAEQCQAAVEGLQLAQDAEIAEQERLGGSHSRHSHRSHQSQSSNTHRSHQSQSNPHPRRVSGLSVAASEDGAHSAVTSETGDESLLQPSGRASSIPPTPDLIPNRSSTAMSFTSSATTPERSSQQYLVREDIPTKIMEDDEDFLENGSESDVMPSEPAMVSKHVTQGLIHRSSGARISALGGLPKRQVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCF9</accession>
    <name>A0ABR3ZCF9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000038">
        <property type="protein sequence ID" value="KAL1898025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="253" mass="27143" checksum="F126D7C2B02864AC" modified="2025-10-08" version="1">MHNLKLSLSGRTGYSTDLEAGAEAIGAKKTTSTTATDATAATAAAYPPSIYPPLRTKALGSRAINQQQPALSSLIIPPMPPVPAHLRTHVPPLSAANPSNTPHLRPWYPPPPTSEIRAQLQQRVTGGGAKKLTLGMLAAAPNSQYRISSFYRDGNYDPAAAEPVSPLSPLLNQLREAASRTHGVPNSSDPNSERPPVLPETPVTPISAVSAVSGRWRSKRKTVLEAVSGWWDLNLLSRQAVAQRRRPHMKGWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCG9</accession>
    <name>A0ABR3ZCG9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PEBP-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001933</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000033">
        <property type="protein sequence ID" value="KAL1898388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008914">
        <property type="entry name" value="PEBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035810">
        <property type="entry name" value="PEBP_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362:SF141">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01161">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046579252" description="PEBP-like protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="295" mass="29448" checksum="CD5C7CE980749601" modified="2025-10-08" version="1">MKTSFASLLTSVTASLAASPSGFLPSSINPLIVAYGKNTVVDGVVMTQNETQTAPTLATSSHLQGTFSIFMIDSNVPSNTTSSGTTTLLHWALTGLSSSNASTNLNGKPAHILKPASNSTAPLAKYIGPAPPARVPLSHQYTLILVNDTSLTSSNRKRLQKAAGTRLGFDAPTVLGATSLSLDTVAASYFNVTNSAKGLVDTGSGLNSTTGNNGRSGSGSGSGSARGSGGSSSNRPAQTNPAASGSGAANSTSISTSGPNPSTTGVISAARELELSRTATVVICLLTVGAGFVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD79</accession>
    <name>A0ABR3ZD79_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002056</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000036">
        <property type="protein sequence ID" value="KAL1898107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="158"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="534"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="605"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="540"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="608"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="655" mass="67931" checksum="34417FF39EDDBB02" modified="2025-10-08" version="1">MKSYFVLQLKHWNGAAELMLCAVPAGSVARAVVCAVPRAAVDKGSSALRENALWAQACHSRTAASVNPAASDVRAMSEAVSTETRLTATTEEILMVAETSISPTPTSAYASNHKAISAESVPTASVTPMTTSNLLPESTPTQTASTTGAISDTSGLPFGATIGLIISSAAVFIVLGFIIALYCRRRRNDRARARAAQMSMVLSPPSPLLHDSPTMQPVAFGGSMRSRSPLGLSYTAYPPYAIYNGNKSRNEKRSGDDRLVAGYMNETASHGIAGRISRTGSAATAGILAGIRSASRSGSRRSFRPLVDADDTSTIDFDDEDEDATEAHFAKLMQEVREPLASTLPRSRSAAPSSVYSAYPSSAAFPPAAYAVSYQVAAATGGDNCAVGAGCVLPIAASMMTTGRKASQSANTNTGTNMNISAGPTNLTRTPSFAASAVAMARNASTGSTSSTMRSHTRSIFFPAPHHDAPFSPPPPAPAPSRPLSNVMGGVGIALSCDEPLYSPLPKTSPMSLAMSVSSVSSAGPAVLRWSQGTGRWSEASAPQAQQAQTNAHAYTQGHGQGQNTQNQNPDSGVAWNSPSWTRMPYVQIGQNAWSYAPTTHHDKDLVTSPSASSVTGSGHASPLISPRTRAVTPVLGPGTGPGFIAELEGSGPLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF07</accession>
    <name>A0ABR3ZF07_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001567</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000025">
        <property type="protein sequence ID" value="KAL1899283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="422" mass="42799" checksum="0779380223BBD542" modified="2025-10-08" version="1">MSHSLSSSSHHPPSTSASAGPSPGSAASFKEPSATDTPPDMPGTPTSTTTSLSGISTIATKDGQRGHFGGSNALLGRGHAYSPSTTSLEAERAERISRLAGLERVSTLRAPPYGSYYNNGNNNANNNVNNSGSFTTTGSDASVPGGPGPDLSHLQQGSTVGNLPSLINGLAPVYFDAQGQPMARTKINTIGTPSATASIVSGDTQRTLDDLDESQSGCSTNIGALDCDSGGGGNPGDDSIASLNYTASSGDMLMLDENMSVSAQSVGGFDDRLSDDGAASLVGFGEGAGSTISGPIYQRRQLSSMTAGTLWGPGPSTGSVNGGDDMDSPGASTGRFGGGSASTSGGMLLHKRVDSSHSLGEMMSVSNRGATGSGGGGSNMTHAAVLEWTQQPAATRRFKSSREAAESILRERRERRSRGQHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZF49</accession>
    <name>A0ABR3ZF49_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001798</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000030">
        <property type="protein sequence ID" value="KAL1898691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="552"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="603"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="552"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="603"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="623"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="655"/>
            <end position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="696" mass="72848" checksum="6B1F2BDF7C166689" modified="2025-10-08" version="1">MCFSVLACRRGCPANQLRKNSAPAATESAEYLRAHGTARPANSLPPQPTREPPALPALDFQTSSLGETTVYHCRQGRQDHVVKKADGPDCSLSHGLVQEPGALNGAEAPMASPKANTPPVSTPSTPSQQQLTLPLAAGQKAAMPLASHPTSTNPSSFLCQGSANSQTSCCSVVAAAGSTSTSTHSPSENTNLGSIAALSTKTLSVSNLAKSTSCGSSSSSPNSASSNSVVQPSGVEAVAVHLSRVPSPLASTVVIPQNSPATKPPATSLDVALWRVTAKNEVEPTTHVDIAVPELKNGDDKRELRESNEAFSKLAQSASNIDAKGKGKEVVKSITATSSDSSEPEWLRRFRRVGSADRPVVVSVYGADGLPLDFDPTNSVHQSEVNLGLHLVALTSDNLRLEPFDIPDKTAGIGKFNADGTMEAIDDHAVPAERKNKRNREAQASSWPHILSRLIKSSNSETSSRLGRLSRSVSRNVPSSSAFPFSGSISASSKSTCHDLTNTNQAPTLAVTAASVSTPASTVVSNITVPAEMVASQQRTDILATSILNSRDRHTWESKQDKELIGPNASETDRNINATFPVRFTRAIMRGSIGRLVPSYSSAAGYPGGSSSRSSSNGSPSEEVARSTGRGDKGLCPVSRASGTESEEVEPQYKVPNTTPETSSVQDDVDATLAKDTSKVGHGMHHPLQTGNCDGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFN6</accession>
    <name>A0ABR3ZFN6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GTPase Ryh1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ryh1</name>
        <name evidence="3" type="ORF">Cpir12675_001639</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000027">
        <property type="protein sequence ID" value="KAL1898979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01861">
        <property type="entry name" value="Rab6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="151" mass="16901" checksum="B6EB4B9E5B638161" modified="2025-10-08" version="1">MYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDVTNAKSFQNTKKWIDDVRAERGNDVIIVLVGNKTDLNDKREVTTQQGEDEAKKNNLMFMETSAKVGHNVKTLFKRIAQALPGMDDAGAQTANQMIDVNVNTSPTTQDGCAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH43</accession>
    <name>A0ABR3ZH43_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">threonine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Threonyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MST1</name>
        <name evidence="11" type="ORF">Cpir12675_001200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Thr) + L-threonine + ATP = L-threonyl-tRNA(Thr) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24624"/>
            <dbReference type="Rhea" id="RHEA-COMP:9670"/>
            <dbReference type="Rhea" id="RHEA-COMP:9704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78534"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.3" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000017">
        <property type="protein sequence ID" value="KAL1899976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004829">
        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00771">
        <property type="entry name" value="ThrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002320">
        <property type="entry name" value="Thr-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033728">
        <property type="entry name" value="ThrRS_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451:SF50">
        <property type="entry name" value="THREONINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="THREONINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01047">
        <property type="entry name" value="TRNASYNTHTHR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="10">
        <location>
            <begin position="79"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1899976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="545" mass="60179" checksum="50C4B1CD23621340" modified="2025-10-08" version="1">MVQFRPIWPLQRGFPCLRHNARPLGTYFRLSARLSSNKSTSSTGNSNPSTDAPDHRVLGVQQSLFATSPYSPGSPLFLPNGTTIFNRLIEFLRKQYIYYGFQEVITPTIYKRALWEKSGHWENYADDMYAVTGRSHQHQKHPGSVTAAAIPASTNVHGSGCSHDHGTADVDAEVDIDDFGLKPMNCPGHCLLFASQARSYRDLPIRFADFSPLHRNEISGALSGLTRVRRFHQDDGHIFCRPAQVEAEIGRTLEMVRVVYGVLRLGVGYRLALSTRPEKFIGEVDEWSRAEAALSRALDASGLSWTINDGDGAFYGPKIDIILQDSDGKEHQTATIQLDFQLPKRFGLEYQAPAPELEARGETTDDPQLLASYGPVAPVMVHRAVLGSVERLMALLIEKTGGTWPFWLNPQQAIIVTVNDTPEILAYAQKVHDLLEGHDEQARQALAHSETRGVPASPLAAFRQPTGLCVEIDTRAESVGRKASQAREKGYGLVIVVGKQEVRDGLVTVSGRSLPVGADGQPRKKSSMTPEELLHMMQEMAATFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHG0</accession>
    <name>A0ABR3ZHG0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001547</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000025">
        <property type="protein sequence ID" value="KAL1899263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="287"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="423" mass="46224" checksum="CB84E492EA45A48E" modified="2025-10-08" version="1">MPRSLPPGWERNETPDLKEKTGLPPLSDQEPIKRQPTAGDGGSINADVEQGDKPLSLPPKINKKIDEVYMISGIGNDDMYCMVEDELYEVAKKFTAHLHEAEYQRLKSEAQSLNVGAGRKIVRPVVSSAMDSTELRIEYASRLEILRKATKKSHGNTEDGADDDGMLDTTLEGSPLRELMQNGSKMDGSLVNRSLQSSENPVRPSSQSYSYGKLLKASQQNTGGLKKVNQQRSVETPKDGAQYKLQPSNLESLRSSNTPSSGLASRHFTPSVSSPPEQSSLPDPRSFRLSRVSSRSQISILSEGDSDDELCVSSPYPSSPPLLAPRRTKTGPVLSSTLMASTPRRTGSYPKANESNSPTRVTIKQERPQSVPATGLTVDSDSEDDDIFIELRRKRKAKTLERKASRVLGNPKSSSAGGKRNEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHT1</accession>
    <name>A0ABR3ZHT1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcription factor mst12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MST12</name>
        <name evidence="9" type="ORF">Cpir12675_001246</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the STE12 transcription factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000018">
        <property type="protein sequence ID" value="KAL1899747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003120">
        <property type="entry name" value="Ste12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052127">
        <property type="entry name" value="STE12_transcription_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47427">
        <property type="entry name" value="PROTEIN STE12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47427:SF1">
        <property type="entry name" value="PROTEIN STE12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02200">
        <property type="entry name" value="STE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00424">
        <property type="entry name" value="STE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="567"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="597"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="411"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="610"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="443"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="476"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="620"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="649"/>
            <end position="679"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1899747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="704" mass="77136" checksum="62DD50ADC9EB9FEF" modified="2025-10-08" version="1">MYSQNGTMVVPQKPETFMLSQEAQQALPADAQVALQQVDNSPVDWQPDQYIRRFLLPTGEYVSCVLWNTLFHITGTDIVRCLSFRFQAFGRPVKNSKKFEEGIFSDLRNLKSGTDASLEEPKSPFLDFLYKNNCIRTQKKQKVFYWYSVPHDRLFLDALERDLKREKMGQEATTLAVAEPALSFQYDSSQSLYEQLTKAQQMNSSSFGAQQVSQAQAVAYQQSASASYSQPQSTSPVMRSVDSMPPPQLMAQNVAPIVDPTIDPMGTYGAMGMAPTIPQQSSAVKREADYSRVQYNTNGVPITQTHQRHASMPAYALEYSPAPSFVSSAYDDYGNRGLSFEPITPPQQAIGMGTEPAYIANEETGLYTAIPDHMANVNAMNGMLQLPASNISNPQFSRAYGANNVYSVIEGSPTYKQRRRRSSIPPPMQGMAHSSAPTSVGHGHAHSVSHSHRPSDLRRSVSLSVGPVLEDDENADNSPPSLYGNVSVTSNPQGQTQSKESGNMSRHGTPLPTVEGSPAMNAIPLQAHEFSSAADDIADARSMTSGVVRRARSATVMELGPYPQKSHSCPIPTCGRLFKRLEHLKRHVRTHTQEKPYVCPHCSKAFSRSDNLAQHRRTHERPDGAEGSVHDEEEDFSGEDQMGFIDEASPNSDNAYIPVSLNSTMTSGTPQGNGNSVSVAPQSIGGYNSMQSLTMPVAMSAPTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHX4</accession>
    <name>A0ABR3ZHX4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ADF-H domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_001009</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the actin-binding proteins ADF family. GMF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000014">
        <property type="protein sequence ID" value="KAL1900325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11283">
        <property type="entry name" value="ADF_GMF-beta_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011171">
        <property type="entry name" value="GMF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11249:SF2">
        <property type="entry name" value="GLIA MATURATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11249">
        <property type="entry name" value="GLIAL FACTOR NATURATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001788">
        <property type="entry name" value="GMF-beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADF-H" evidence="3">
        <location>
            <begin position="4"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR001788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1900325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="142" mass="16042" checksum="340D7DC6F84E92C7" modified="2025-10-08" version="1">MSSEARLYNFSQDTRTHLRKFSLSTSRSKEPQAVIYLIDKNSYEIKQQDQTVYNSLEDISDALPDNSPRFVLLSYPLTLTDDGFKPVPYVLVYYLPATCNAGAKMMYAGAKELMRSTSNVGKVFDIEDAEDILEIPAKLGQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI26</accession>
    <name>A0ABR3ZI26_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Folliculin-interacting protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000014">
        <property type="protein sequence ID" value="KAL1900316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028084">
        <property type="entry name" value="FNIP_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21634">
        <property type="entry name" value="RE13835P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21634:SF9">
        <property type="entry name" value="RE13835P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14636">
        <property type="entry name" value="FNIP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Folliculin-interacting protein N-terminal" evidence="2">
        <location>
            <begin position="90"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="8"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="633"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="740"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="795"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="234"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="633"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="651"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="696"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="764"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="798"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="811"/>
            <end position="822"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1277" mass="138420" checksum="C77BB01257A391DC" modified="2025-10-08" version="1">MLGKLFNLGSGSNSPSSQQQVSSSSSKPVLSLDSVQEDIHTRTLLFPDPQALQQFQGDQLFPFTSLSASIAAAPIQPFDYNPDICIDNHDVRVIVMQDGMGSSVSSSLLFDSHPFVAPTSPSSATADRGTIPETCKSPKQSRRSSVPYASATVGGRAMQFEGPQLRSGAFDRRSSTNGRFPSTIETEAQKAGREYREEMTTFMSCTFGNSEMSSYKGTSTKVHLYSSDQRRSDISSTSISGDSKGLTGRAGGTRSRLAHSYSSEVMSPGFPPNLSYGTSATANSNVSPSDSKRVLISRLFPVVVPTDNISLAQTQEDLVFKRPHPRPKRTPMYAVVLVINLESLSALGNKTGNFRGSESFTENESLPSSFGSGRRMAWNTPGSAAPEPVEFCIPESDDRMEHITKHWDIIRRTLTQLQSVFATSISNMLKQLDMAIPDPSSPCPSHRALPINTKSNSKLLALSPHCFCNDLWLAKQVNIAQSRIVSGLQAEHVCTGQGRWSTWRDEARVISRLQVGHGIDGRDFFYRLLTGFLATHTHWLQALGPDLYRQRHIEREKLKTDEDFMYPARTIIVGKDKMAARRLIFLLSAFLPSKENMNNINSLRPTTSTSLNFSASPPGYTISALTKEESLRKKINRRSGKSRVPSHHRTPSQSTRNSLVPSALAHLTLDGGQYHGRQDSDDISNRPPPPPLPSIHSHSGQSLVNTAASEKKLRKSSIAATTTAMPEPAVAHFAMLHRHEKLRTHRPSSSSSIAADDLKRSLQRSESMSNGSDSTASSSRWGSIMSGLWGGTVRRESVTSVTQSHVSSPIRGGGGSGTGAGANAGSAGSGPRTDPLSPRKSTDKRQELIASLGFTSEQLSSASALQVPISDPELSPGHVIAPPDLDLRHAQNSSGLRSAAEIQPRQPIDMPHPFGSPVKTSINPEDGVIDIDIPFTDFLASFETAVSSPSSGGYLSTPGINHDGLASFERSCRLSSDGDTPLNVAGWLKAFHPDFILQAVPPDEHLMNQIQEALRNEPSPACFVSSYTSNSEPPTERWVDVSSALVADMTKGTISRIRYRRLIVPRERPIPSRSGKGGPYGGSNLVTPSIKPYEIRHDEHFEVERVGTVEDILTDAIDRVIAQAGDLTSVSSMSDIAGPKSIVGSLKTQTNNRLEPEVSMMVSSSMPPPSSIFPSLLPSISMPTPSLRKTAPRDVPISIGQQAPREVSRAECKSVVLSSLAHLVRDVLDKRDLLAAEDGDDDTYADESVMRGAVRAWLNAAESTLENSPPGVHVRGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIK0</accession>
    <name>A0ABR3ZIK0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">laccase</fullName>
            <ecNumber evidence="4">1.10.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">lcc1</name>
        <name evidence="15" type="ORF">Cpir12675_001138</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4 hydroquinone + O2 = 4 benzosemiquinone + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11276"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17594"/>
            <dbReference type="ChEBI" id="CHEBI:17977"/>
            <dbReference type="EC" id="1.10.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.10.3.2" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13854">
        <property type="entry name" value="CuRO_1_MaLCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13901">
        <property type="entry name" value="CuRO_3_MaLCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF87">
        <property type="entry name" value="LACCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0439">Lignin degradation</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046774223" description="laccase" evidence="11">
        <location>
            <begin position="21"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="14">
        <location>
            <begin position="75"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="12">
        <location>
            <begin position="200"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="13">
        <location>
            <begin position="426"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1900032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="585" mass="64124" checksum="94BB1DB925EB3666" modified="2025-10-08" version="1">MKSSIFALGCISIVANSVLAIPTTISQEVGKRASTCNTAENRDCWSDGFSIDTNYMESFPDTGVTRQYVIVVSEAENISPDGIVKPMSMLINGSSPGPTLYADWGDNIEVTVINELTTNGTSTHWHGITMMNNNPNDGVNGITECPTAPGKSKTYSFRAEQHGTSWYHSHFSTQYGTGVSGALVINGPATSNYDIDLGPYMISDYYYKTAEEIYSTIIIPSPGIPPSADNILFNGTHVNADGGGSYSVIAMTQGKTHRLRLINPSVDAEMILTMENHNFTIVAIDFVPVTPRTVNQVFLAIGQRLDVIINADQEIGNYWFNMTFPDSGLCGSSTIDSPAAIVRYEGAEEVNPTGSGTTPTDLSCQDLIDFVPHIPVTVPSESFNDDLSDSIDVNLVNNAWRDIESRVYWTVSGSSMNISWGYPTLAYLRDGNEDYPAQLNALKVADDQEWSYWVINNELALPHPMHLHGHDFYILGSSGVVDVATTFNSTNDLASLNFVNPTRRDVTMLPGLGWIVLAFKNNNPGAWLMHCHIAWHVGSGLSVQFIERPSEIKTLFDLDTILDPTCTDWNTYDAEAEFHQEDSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIL7</accession>
    <name>A0ABR3ZIL7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Magnesium-dependent phosphatase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07501">
        <property type="entry name" value="HAD_MDP-1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010033">
        <property type="entry name" value="HAD_SF_ppase_IIIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035679">
        <property type="entry name" value="MDP-1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010036">
        <property type="entry name" value="MDP_1_eu_arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01681">
        <property type="entry name" value="HAD-SF-IIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01685">
        <property type="entry name" value="MDP-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17901:SF14">
        <property type="entry name" value="MAGNESIUM-DEPENDENT PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17901">
        <property type="entry name" value="MAGNESIUM-DEPENDENT PHOSPHATASE 1 MDP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12689">
        <property type="entry name" value="Acid_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01131">
        <property type="entry name" value="C1.5.2:_MDP_Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="238" mass="26437" checksum="345E0BF84A24B29B" modified="2025-10-08" version="1">MAPKSKLPAPSTDFLPSSLTDPALPLPTMIVFDLDYTLWPFWVDTHVTPPLKPTDAFTAVDRVGESFALYREVPSILHALSRAGIQLAVASRTSAPELAREMLKLLHVPAPPPLPSAIPPSAERGRGGRGGRSGGGGGIVDLDDEIHWEKPRRALELFDAPLEIYPRSKIAHFEALAKKTGVKYEEMLFFDDENRNREVESLGVTMKLVRDGVTWDEIEKGVEAWWRRRGHVTKSLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJD9</accession>
    <name>A0ABR3ZJD9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Iron-sulfur cluster assembly factor IBA57 homolog, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CAF17</name>
        <name evidence="7" type="ORF">Cpir12675_000711</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the GcvT family. CAF17/IBA57 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="entry name" value="Probable tRNA modification gtpase trme, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017703">
        <property type="entry name" value="YgfZ/GCV_T_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045179">
        <property type="entry name" value="YgfZ/GcvT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03317">
        <property type="entry name" value="ygfZ_signature"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22602">
        <property type="entry name" value="TRANSFERASE CAF17, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22602:SF0">
        <property type="entry name" value="TRANSFERASE CAF17, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103025">
        <property type="entry name" value="Folate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="433"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="441"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00093447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00093637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1900835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="453" mass="49702" checksum="83E7434C1DA8B761" modified="2025-10-08" version="1">MNLSRCILTAPLRSRTASVCTTCLGRPFLQRRAVGNAAPKPTVEPFLSGVSALPERRLISVSGPDAAKFLNGVITAEIKGDGPHPPVQYAGFLTARGRVVNDVFIYADVLGIGKDGPEASFLIEVDASEAQGLERLIKKYKLRAKFNARLLDQGEVGLWVAWNGKDKAALNRDILQRYYGGPVIAAADARLAQLGSRIISPYSHKSPAGVLGIKSVPPEAYRLRRYLHGIAEGQGEIMKANALPMEMNMDILNGISFSKGCYVGQELTIRTRHRGVVRKRLLPCVVYTEEEMTPKGLEYSSHGDLTANIPQNTGVFRALKKRRIRSSGRWVGGVGNIGLALCRIDLMAGLTIPGEEPDALEVYNPFAEFDMKFQPKNEVPIESRVPDPDGITEEPVDKDGSAIMEALSANNKVEHTLRIKAFAPEWMRSALDQQLGRAKDEEIEDEGEENEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJE8</accession>
    <name>A0ABR3ZJE8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DAGKc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001026</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000014">
        <property type="protein sequence ID" value="KAL1900342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050187">
        <property type="entry name" value="Lipid_Phosphate_FormReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358:SF108">
        <property type="entry name" value="DAGKC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358">
        <property type="entry name" value="SPHINGOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAGKc" evidence="1">
        <location>
            <begin position="88"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="445" mass="48875" checksum="7DCB6E06ADF709D6" modified="2025-10-08" version="1">MSRCSPASKEWTEPLSTNATSSFDAIFDDPQSIVAIFKQARGFTVFAAFDTGHGVDVSYSIKCIDVPAVPSLLEPLIISRCPRHLQVSDSRKLHVVVSTKSGLCLATKCWNQVVKPLLNAVQSLSSITHTGQYSLLITENAESIKSFAAKILRAEESAQTVLLLSGDGGTVDLINAMNQDEKQPSPTTIAILPLGTGNALFHSIHRQLYSNGTESALILGLRTLIHGTPVSLPLFRADFSPSARIVTFVQSQNNMTSRPVEYLYGSIVASHGFHASIVYESDTPEYRKHGDKRFGMVANELLELNHAYKATVEVRLPDYSGFRSLGGNEFNYILSTLVSNLERTFTISPDSRPCDGKLRVVTFAPLSKDKAMEIMMAAYNNGAHVSMPEVTYEEIKELRVSVHEPDDRWRKFCIDGTIVAVQEGGWMKVKALSTSPFQVLTTPSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKA2</accession>
    <name>A0ABR3ZKA2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PHO85 cyclin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PCL1</name>
        <name evidence="3" type="ORF">Cpir12675_000647</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000008">
        <property type="protein sequence ID" value="KAL1901158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF10">
        <property type="entry name" value="PHO85 CYCLIN-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="2">
        <location>
            <begin position="82"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="282"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="385" mass="42759" checksum="816C136454940338" modified="2025-10-08" version="1">MDPSVVGPVASDDLNAAALEQFIYQPVTTTMIAYLAQAAHNVIVCDPNLMPAPIPDCSGPSAKPTATAMVVGPQDGALPSLEAFITKLVVSSKVHVPTLMSSLVYLNRLRSKLQPMARGLRCTAHRVFLAALILTAKYLNDSSPRNKYWANYSNMCGENFDFGLSRKEVNLMENQLLSLLEWDLRISPEDLYTELDFFLTPFRQQIADRRRRRAERKRAQQEDRRRKEEEAATLLAIRELEREQYYRSYANQMPSPPSSRGHSCTRPTTASAEYFPSSTDASSPPGLSYNSSGSSSTSSRATTPLDGSTDEEAYIYVNSGSAQSPVEVYESPLMSSKIRKAPSNYSALELNDPNSFDPRDLPKPKRARRARGVFGRMFSNSTATM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKB2</accession>
    <name>A0ABR3ZKB2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000008">
        <property type="protein sequence ID" value="KAL1901146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="975" mass="108614" checksum="05ED390C238BB750" modified="2025-10-08" version="1">MTLPQPQTFSFEEIGDDITLAIYSSISHLFPPPSNDRENQSDARQGRVTRLALVSGSPKRDLFSDSGINVATRFRRLLRNPDGGAIDEDDSSSEIDDDDSNSETDDLSVADQDDYQSGYYDPLQPSRGFCSFRHAQVHSLENQIIAGAELASRNSSSEDEVVDTAQIEIPTAATPKASGFKPSTAKESADAAKDSAFATHHHLEYSSFRDTRLCEMETFVNYGWNIGMESCVTLAPTDYCFVCHNTTIHGEFSRCYCISCFIEKSTDPYSTYLQNNPQVEADYYFLASIGPSRNKQPVLIDVDPASVGIGHDSKKPFKIASKNGEPQMCRLFIPQSSNGSQTLVRNAYQGYRAFTVHKTCFKTVHTLAKHLDYSLNQVIRSMYEYAASVLPVNGLELTREIRPSLDLTNIPPLARSSLSSSTGKLFSSIMQLPSELQDCIIQQLDNSCEAARIFHAYKLAPCILTRTEHPRLYRNDTSWIKLLSQNNLDSKGLTEIPRESDSFILSAEYWTMGHVTYMANFRVISALDSTEWKSDEHCDKYLTVFNVHVTSIANIHYYETFTGPYGVTQISVFFKDGSQPGVLGRARKADLRFRVFCPLPQLVQFGNRLVDVIETGLEKSETSVVTQSIWASEMPPVGSVVCSSGFRFVTGHHFSYLPFEKDGVHCVGVTAHANRNGITSVIVHHANGTDHTVSQKKLFETQLPEIPLTFMLRRHEIITGLWRVVAGTTDISGSYFAVFTNQNRSFLFGPILASIRQLARWSTLTDQSVTKVKGIALDVAPNGNSIQHIAAIFDRVESTRDDMGVEIPSDRTQLIRHSIYGMGSWEIYNSFGAVDNCVCIDLGLLLSQPVAMKITYSDGTYSILGRWATKGLQISTVYNAETDGEIESFHVQDSSITRPNRGMPFIMDLQVSSSKRKISAPSRTDVTILACTPGLVLRWTYSYYSSFLEAWDGLCAYHDGQNGAYTDGYKMILEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKE3</accession>
    <name>A0ABR3ZKE3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Gag1-like clamp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000740</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053274">
        <property type="entry name" value="Fluconazole_resistance"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025124">
        <property type="entry name" value="Gag1-like_clamp"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28065:SF1">
        <property type="entry name" value="DUF4050 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28065">
        <property type="entry name" value="FREQUENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13259">
        <property type="entry name" value="clamp_Gag1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gag1-like clamp" evidence="2">
        <location>
            <begin position="292"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="493"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="507"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="557" mass="60965" checksum="8FCEE5A8A3397CF1" modified="2025-10-08" version="1">MVASKANTTTEKISPETRELDTLALIKGMTSTDTAAAAVGAGAHNSQNSLYPHPQHIPEPQLLTLKPEFYQPKEFNSFDHPAPPAPINNDFDISLTGATPTSASNMIFTELYRSRRATLSKVRSSQSSTATPNDASAQDFDPNFLSRDKSKQREAIRKYLAKNVKNDWEFAWTRTDVPALPIVVRRKVVNRAVTEVRYHDPAVSEPAATTSLAQVLKRREGRPASAADPVIRDSGEEADSASENEYSSEDDDNESVYSVMTEDETRFKPRLEWDSELSSIDSVLEPISPELLESASPHEIILLNKERRRKAIKEEMKWNQGLACFEIRRNKWTCAKVARLRPKTTTLPIADATSPSTSPRSPRRLFFRHSTHSNASAGSPTSTNATSINSDSDIAVNSTSKASIDTSESQPTSAAGNTKIDQSDSKHQIYPVETLLPVAPPLLPPQNPMRASISPKLYLALYDRTIIQSMTPSCPINLSDMLPACVAGWMRDGEWPPKTAPPPSPAPARSSKTTAAASNPRRRSFGFLTREEEGAGVSKGFRRGIQKVLGLGGGAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKJ1</accession>
    <name>A0ABR3ZKJ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="324" mass="39076" checksum="0A7BDC85B05E5A8C" modified="2025-10-08" version="1">MARKRDADNLAQKDAQLVFWTVQNPRFARLEHQSREELTQFFDYYTKQLKSLNARHESYLSQSLKAKWNSARTLLDSVVERQNKTLSSVDDLHVRQEAQLIQQQSSKELKLNVHIERLQKHWNSIIPNSSLHRSHLQEQMESLKRLQRRHSLEIKFLREAQQRIQDDIHERFIKERKVSAETQQRRERRASNMISREESIFQTAFQRRLESLWKLWALRWEELCLQLRLESHGQYARFRPTWLQEVDKEEVRFVITELRSVLITHYGKEAVDQLVRSLAGEEKESDSVSLWEWEDEDEDDGEDIDYHDFVRPWKKARKATRQSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKU3</accession>
    <name>A0ABR3ZKU3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rab proteins geranylgeranyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Rab GDI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.405.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.519.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018203">
        <property type="entry name" value="GDP_dissociation_inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017230">
        <property type="entry name" value="Mrs6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787:SF4">
        <property type="entry name" value="CHM, RAB ESCORT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787">
        <property type="entry name" value="RAB GDP-DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00996">
        <property type="entry name" value="GDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037514">
        <property type="entry name" value="Rab_ger_ger_transf_A_fun"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00891">
        <property type="entry name" value="RABGDIREP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR037514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="491" mass="52989" checksum="0D3A46D1F6282791" modified="2025-10-08" version="1">MESLADEVWDVVINGTGLQQSLLALALSRSNKKILHLDCRNYYGGPSAALTLDEAEAWAIENAASNDDSRIFRGATFAKCDDAIASLGPSRAYTLSLAPQMIHCRSELVSQLVSSQVFRCLEFLAVGSFFVYQSEKDGQKPSLVKLPSTREDIFLTTTISAKAKRGMMKFLKLVLDYDSEENKSIWKPHATDFLSDFLASSFKLDSSMQTLITTLTLDLDDKITVQNGILAIHRHLNSTGVFGPGFAAVYPKFGGLSEVVQAGCRACAVGGAAYVLGTGVKASRPISEDDAKVEVDLVDGVTVKSRALVTSLETPCGNKVASKLVAVVDAKPESIFQASVEGAQTPAVAVVAFPAKSLLEDQEHPVYAMLHSSDTGECPVNQCIIYLSSLAYACSKLALSKALESLLFIITTPKCPAPKPLVQIYYEQADSPSSLTIDGNIITVPCNTSDLAFGDGLLKPVREAWEVLTKNDEDAGEYMKFVDRKPVDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNT1</accession>
    <name>A0ABR3ZNT1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_000006</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008733">
        <property type="entry name" value="PEX11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652:SF23">
        <property type="entry name" value="MICROBODY (PEROXISOME) PROLIFERATION PROTEIN PEROXIN 11B (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05648">
        <property type="entry name" value="PEX11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="1" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="193"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1902109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="303" mass="33228" checksum="296045201DDF4AE6" modified="2025-10-08" version="1">MPSTTEKLFALGNDLNGLERLFRGFQALLHLATTTPVIDTAVTAIVPQELSPGQLQHAKASLNVTRRFMRLFAFGHAFRAAQEAVRIGDRTKAADASAGPWRVSSHIGSPEALLDALRGSFFCIHGLLESITVLDLAGIPVWSTARDEQLNREAMRMWVAALACSLLVTLMRMFALYAYGAVNAVDSFGDMDEHEEEEYEKDKEGDEREGAKEKGGGDKVKREKAKSKQKPALSPAQRRRQAAAAAAARKSAMHKLQRRVVADALDVLVPASELMWVQVNDTTIGVVMLMTTLLGFVDTWGTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNZ2</accession>
    <name>A0ABR3ZNZ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nicotinate-nucleotide pyrophosphorylase [carboxylating]</fullName>
            <ecNumber evidence="6">2.4.2.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Quinolinate phosphoribosyltransferase [decarboxylating]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">BNA6</name>
        <name evidence="9" type="ORF">Cpir12675_000033</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the catabolism of quinolinic acid (QA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>nicotinate beta-D-ribonucleotide + CO2 + diphosphate = quinolinate + 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:12733"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29959"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from quinolinate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Hexamer formed by 3 homodimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the NadC/ModD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.19" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01572">
        <property type="entry name" value="QPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.20">
        <property type="entry name" value="Quinolinate phosphoribosyl transferase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004393">
        <property type="entry name" value="NadC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027277">
        <property type="entry name" value="NadC/ModD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037128">
        <property type="entry name" value="Quinolinate_PRibosylTase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002638">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022412">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00078">
        <property type="entry name" value="nadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32179">
        <property type="entry name" value="NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32179:SF3">
        <property type="entry name" value="NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01729">
        <property type="entry name" value="QRPTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02749">
        <property type="entry name" value="QRPTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006250">
        <property type="entry name" value="NadC_ModD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="Nicotinate/Quinolinate PRTase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54675">
        <property type="entry name" value="Nicotinate/Quinolinate PRTase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3 6" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Quinolinate phosphoribosyl transferase N-terminal" evidence="8">
        <location>
            <begin position="53"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Quinolinate phosphoribosyl transferase C-terminal" evidence="7">
        <location>
            <begin position="136"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR006250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1902135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="316" mass="33351" checksum="1BD4598942072AA1" modified="2025-10-08" version="1">MPLDLPVMALDMPLEHGTLEHLLPASWKTQITAWLAEDTPSFDYGGFVVGTVPRTATLWGKSAGIVAGVPFVNEVFAQCGCTIEWHVPEGAHIATHSEAAQALGGKMRLATVTGPARGILLGERVALNILARCSGVAAASRQMALVVAAAGFRGRLAGTRKTTPGFRLVEKYGMLVGGADAHRMDLSSMVMLKDNHVWSKGSISDAVAAAKSVAGFSVKVEVEVQSEAEADEAIEAGADVVMLDNFTGDGVKVAARSLKQRWAGKKHFLLEVSGGLTLDNAELYVCEDIDVISTSAIHQGVSHVDVSLKINPPSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ11</accession>
    <name>A0ABR3ZQ11_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">General transcription and DNA repair factor IIH</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Cpir12675_000044</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the GTF2H2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01453">
        <property type="entry name" value="vWA_transcription_factor_IIH_type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007198">
        <property type="entry name" value="Ssl1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004595">
        <property type="entry name" value="TFIIH_C1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012170">
        <property type="entry name" value="TFIIH_SSL1/p44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00622">
        <property type="entry name" value="ssl1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12695">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12695:SF2">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07975">
        <property type="entry name" value="C1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04056">
        <property type="entry name" value="Ssl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015919">
        <property type="entry name" value="TFIIH_SSL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01047">
        <property type="entry name" value="C1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 11" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="VWFA" evidence="13">
        <location>
            <begin position="79"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="375"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="376"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="418"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR015919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1902145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="512" mass="55427" checksum="B9973E6757B76FC8" modified="2025-10-08" version="1">MADSDGEISDYNGKSKRNKNGARNGGDRKRGAWEEVNRSWDTVVEDEQGGLSLAEVLEAEKRRRLMRDTTPLQRGIIRHLMLVLDMSFAMAEKDMLPSRYRLVFSYAADFVKEYFEQNPISQMGIIGMRDGVGIRVSEISGNPEEHLKQLHKWQTEEEPQGNPSLQNALEMCRGALFNTPSHGTREVLVIYGALLSSDPGDIQDTVANLITDRIRVSIVGLAAQVAICAELCQRTNAGDKSQYNIALDEGHLRDLFLAATTPPVTRTAEQAAPSLLMMGFPSRTVAAGSANAVAYCGCHNKLFREGYMCTRCGCRVCRLPASCPSCGLTLILSTHLARSYHHLFPLKNFVEVSWADAARSISCYACQTPFPRKPSATDTTASGNNNGNANGAANDSTASANGKTHQKTVPESGSVVAGHKEQMKRTELKGVSESGRYACILCKNHFCVDCDVFAHEVIHNCAGCQGDTRAAIAHSQIRANGNLKSGANGSRSVDGASNGVLSHASNAAMVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQC8</accession>
    <name>A0ABR3ZQC8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ran-specific GTPase-activating protein 30</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">YRB30</name>
        <name evidence="2" type="ORF">Cpir12675_000128</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008812">
        <property type="entry name" value="Ran_GTP-bd-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31010:SF2">
        <property type="entry name" value="RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31010">
        <property type="entry name" value="RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN 30-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05508">
        <property type="entry name" value="Ran-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="500"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="507"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="527"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="621" mass="68614" checksum="33516E45DDD70801" modified="2025-10-08" version="1">MESLLAKIGAQAMNMAIRSSLGLTSAYAFSQYSRLLATIEDGDVFQELKALEAKLESKIKIIGPAIDLIELRSKRGNIFLESALPLARQLQNDITSLGRRLESAASITETQAQKVSSSMLTSGTQTHQVEQVLSDLRSLLDDIDCNIPLLQLAITASGESLSASLPNNVSPSRLLQASTLLIMGDTRYVEATTPFTIGPDFRLSIYMSFLGHTKVNCMPNVLDSSNVGSPSDSKPVWQEVIHKARVRIIRLPFETRFDHIRGYLVGNSCGYIASEYVYHLEVIEDLDDGRLHESPNGARNYQEIAKAGIRESIPLHQISKIFYTDTGRLLNIGSEDSLCNKPVLLLKRDTKAQSTESRVLDHSKWSFGEKAQAKRDSCNMDLSVQHREQGTIDMADDLQLDLQIRNEASLCHNKSRAEFCFPPHLDPEWIALEVFEDGAEGGEDEEDEAEGADKGDEDDEEDPDASDSSSQSQKSLEKVLPRGSSFLCKLKNMSLAANLPGAKTHNSQSQVSSVPAQQQRAVRLQPTPSPQPPPQPKDLVSGGPFNAIKTSLSLMEMLIRLAGLQEFQQMCHLSIPDHLLTFFLEQSSTTGLTGLNQQKVREEARRRVGFDPYTDTPTNND</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZRR4</accession>
    <name>A0ABR3ZRR4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000079</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17039">
        <property type="entry name" value="Ubl_ubiquitin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.70">
        <property type="entry name" value="Get5 dimerization domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049256">
        <property type="entry name" value="Get5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024737">
        <property type="entry name" value="Get5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17183">
        <property type="entry name" value="Get5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12754">
        <property type="entry name" value="Get5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="62"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="202" mass="21657" checksum="E27BFA89106849B3" modified="2025-10-08" version="1">MATQVSFAQGFLDRLAVLPITLTADYVEDPRRFPGRPAYTLPKMPTPMSKRTVLAPGAERSIDVSLKSARNPPLDISLTAQPLTVSVADLRAVVAERTGAALAKIKLLFQKKPVVDSKTLKDLAGEARTSIELGIMILGGAAALPKGEPVAVADKAVLGPENVLKKDEFWAELQVFLMSKLKDEKAAADLLATFKSSYAAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YAK5</accession>
    <name>A0ABR3YAK5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_006996</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000516">
        <property type="protein sequence ID" value="KAL1885336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="123"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="71"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="92"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="114"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="160"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1885336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="173" mass="19699" checksum="05F8829B83E3A1A6" modified="2025-10-08" version="1">MEDLSIREYLARADRLMVRANWATLSEKSKISTVKRGLTRFYKEKMASTKVYEKYEEYRRDLLVLDSSLGYSSCEDEPAQTSKAPSRKGKSYTPTRNENSSGGRRRARWVSAAEQERRRKEGRCFRCGMSSHSIRNCPHAGPIPPGNTPNKVRATRDVPDLESSDSEEGNSEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YCS7</accession>
    <name>A0ABR3YCS7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Adenylate kinase isoenzyme 6 homolog</fullName>
            <shortName evidence="7">AK6</shortName>
            <ecNumber evidence="7">2.7.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Dual activity adenylate kinase/ATPase</fullName>
            <shortName evidence="7">AK/ATPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">FAP7</name>
        <name evidence="8" type="ORF">Cpir12675_006874</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. Involved in the late cytoplasmic maturation steps of the 40S ribosomal particles, specifically 18S rRNA maturation. While NMP activity is not required for ribosome maturation, ATPase activity is. Associates transiently with small ribosomal subunit protein uS11. ATP hydrolysis breaks the interaction with uS11. May temporarily remove uS11 from the ribosome to enable a conformational change of the ribosomal RNA that is needed for the final maturation step of the small ribosomal subunit. Its NMP activity may have a role in nuclear energy homeostasis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>AMP + ATP = 2 ADP</text>
            <dbReference type="Rhea" id="RHEA:12973"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Interacts with small ribosomal subunit protein uS11. Not a structural component of 43S pre-ribosomes, but transiently interacts with them by binding to uS11.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the adenylate kinase family. AK6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000400">
        <property type="protein sequence ID" value="KAL1886067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:AMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00039">
        <property type="entry name" value="Adenylate_kinase_AK6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020618">
        <property type="entry name" value="Adenyl_kinase_AK6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12595:SF0">
        <property type="entry name" value="ADENYLATE KINASE ISOENZYME 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12595">
        <property type="entry name" value="POS9-ACTIVATING FACTOR FAP7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13238">
        <property type="entry name" value="AAA_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2 7" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 7 8" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="NMPbind" evidence="7">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="LID" evidence="7">
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            <end position="120"/>
        </location>
    </feature>
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        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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        <location>
            <position position="17"/>
        </location>
        <ligand>
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        </ligand>
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            <position position="18"/>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
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        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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    </evidence>
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        </source>
    </evidence>
    <sequence length="177" mass="20059" checksum="53F9177AE10ABFF7" modified="2025-10-08" version="1">MARTQPNIIITGTPGVGKTTHCEIVAERVGLKHLSVNQIVKDRECHDGYDDELSCYIVDDDKLLDAIEDEVANGGYIIDWHACDLFPESWIDLVVVLRAQSETLYDRLEARNYAEAKLQENLDSELMDVLITEAREGFEESIVVELNSNTTEEMDENIDRISSWVKNWRKDNAAGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
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    <name>A0ABR3YFG3_9PEZI</name>
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        <recommendedName>
            <fullName evidence="11">Seipin</fullName>
        </recommendedName>
    </protein>
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    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
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            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="protein sequence ID" value="KAL1887026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
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</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
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    <name>A0ABR3YG21_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    <organism evidence="1 2">
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        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
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            <authorList>
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                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
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                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="protein sequence ID" value="KAL1887084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <evidence type="ECO:0000313" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="195" mass="22155" checksum="0BB4067EF4B35BA3" modified="2025-10-08" version="1">MYRDFAIDGIVLIELDADLPQTVRSLCFPNVNIYLIPDHHLVEARAIAEFHGLFPSAEFSLTSKPPSHPRDLSTKVVQYTTNHIDTPSLEAGRLFLVPLSLAGISEDVALPSVPLDANTENVCPVLRVPLRQARIVLVKIIMRFMRYQRSKMRKDYAEMLYKCVVCAISSVVFTKQKLTDKQLETRARRSRLTED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGF5</accession>
    <name>A0ABR3YGF5_9PEZI</name>
    <protein>
        <recommendedName>
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        <name evidence="2" type="ORF">Cpir12675_006838</name>
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    <organism evidence="2 3">
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
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            <taxon>Microascales</taxon>
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            <taxon>Ceratocystis</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
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                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
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    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000390">
        <property type="protein sequence ID" value="KAL1886932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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    </feature>
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        <location>
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        <location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="824"/>
            <end position="850"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1886932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="881" mass="93210" checksum="2DD51384BA80B189" modified="2025-10-08" version="1">MTTTCVSIANSMALKPNLTVGDVQNTSKATQPQATLSTVSEHGEPVSAVGSSPRLPRPIPREPQTSPVSKTRHQPSTPSTSVAKPPASEMHPSKIHRPSLVPSSAIKHGFRDLNPTTRTEQLLAAAQATPTKPRETHARPHHTMPSSPFTFSVTHPSGVEKGLSNEALKIMDGLREEAAKIKAGLIADRERDREQAESLADRKFAQPKGKSNRYSAVHMAEFKKMDSIENHPSAFRAALGRFTPVKALKRKPSKANLDDATEPTIRQVGIKRSPSKASLADEVAATPSTPSKIPGPGGFRSGISSVKRLKQKLEDDAATTRPVSRDGTNISSAIPRLISSGDSPLKQQSQRHPNSATSFGTPTKSGVARPTDFSSTIRLVKSASKPHLVAESRAPTQAPATPSAIPRCVASAVTSTQTKASGTPGRFEHIKSILKKTTIPSAASGTVTNIMCDTGAQESSEKTTSNDAVFDTPSKALTGYRLPEKVVTTPSHRLTKHSVNTPRLTTVTPTSHVSPSFKSAMKRVRMVVPGDECLTMESALSKAETALEVKYPDLTTFSGLLENDSDMPDIDEAKSPAVPGTFSFRSDKTIDFGISKPSFGSSAGQASIRQVRRSVFGGISSGASAGIPGGFPKSQLEAMPNAPTMDPTETDVAKDAGGSNKENDTPISDSKLDGKYRAISHGIGNKKRNRPSTDEDDQARDVERGNKKRRNEDLPLGISVTSTQTATTTAGSFETRPKTPSASVINTTTTMSTATPTRTPGYAAATSAVKNKEFLTRKIRQPVRPTEKLKTAAVAKTVNNSASATPSRVVPSRAGSSRIGAPTPSRSTAPTAESRATATANPSRIKTTASGAGASPARPQVRATSSISASRLAMLATPKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGP0</accession>
    <name>A0ABR3YGP0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_006765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000370">
        <property type="protein sequence ID" value="KAL1887002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1887002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="224" mass="24946" checksum="5AB310140A3F5FDC" modified="2025-10-08" version="1">MGLIDSQIIRTAQGEDPGVTLKDCITQKALVHHALQGVPEISSFSLSHESLCASNIIVDNNYNVVGIVGWGFSRPLPIQFALRFPQFLTVDHDINLVNPDITDLGSNGLLPISLTLHDDRLFFLTSVLTNVESQSPSADIRRWVSFAFADPNSNWRHLIVESVLKPDVYSWMAKCGWLLDVTKELRPTKEDLIREVDGFEEFLEHNAGSIKGPDRKTLLKAVGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJB8</accession>
    <name>A0ABR3YJB8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable kinetochore protein NUF2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">NUF2</name>
        <name evidence="18" type="ORF">Cpir12675_006192</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NUF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000263">
        <property type="protein sequence ID" value="KAL1888411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.60">
        <property type="entry name" value="Ncd80 complex, Nuf2 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005549">
        <property type="entry name" value="Kinetochore_Nuf2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041112">
        <property type="entry name" value="Nuf2_DHR10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038275">
        <property type="entry name" value="Nuf2_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21650:SF2">
        <property type="entry name" value="KINETOCHORE PROTEIN NUF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21650">
        <property type="entry name" value="MEMBRALIN/KINETOCHORE PROTEIN NUF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03800">
        <property type="entry name" value="Nuf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18595">
        <property type="entry name" value="Nuf2_DHR10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="13" id="KW-0137">Centromere</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10 14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="8" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinetochore protein Nuf2 N-terminal" evidence="16">
        <location>
            <begin position="29"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Nuf2 DHR10-like" evidence="17">
        <location>
            <begin position="278"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="326"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="171"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="332"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF03800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF18595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1888411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="459" mass="53526" checksum="D74C577A5F9BD80E" modified="2025-10-08" version="1">MAYNHRMSILPQQQQGRNRKKEPEPDAFMLSDKEIVGCITDIGITFTIANLQKPNPVQVQQIFEWFAELLLNSTRETVEPAMRAAAEDVCGEYSDIIPADTRNLMGFYVSLRRLLTECGINDFSFNDLYKPSHERLVKIFSYVINFIRFRESQTNVIDEHFNHSQKIKSRIETLYIENQDKEALLDEMRINRQAMEVQVREKQMRNEELKKTLLELRRNQEKVAIHLEEAKVKKGELATELEAKTTTKLMLKQDSAKLRPYASQSPSALQASLSDLGNTLSSDRSHIDALDRRARALQTSADSFTVVSADVASCIKMLDEIATELSKEEEENAKNSRQRDALSERGNNVREVERAEAMLQRQLQKWMERTEKLREQSTMKAMEAKEKMEELRALHKKLTEERTEKAKEMERRRVRIEQTEKKMLDLKENIENEVHAAYDEYLKMEAHIKLYMTEMEQAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJC2</accession>
    <name>A0ABR3YJC2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PB1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_006194</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000263">
        <property type="protein sequence ID" value="KAL1888413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06409">
        <property type="entry name" value="PB1_MUG70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="286"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="PB1" evidence="3">
        <location>
            <begin position="114"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1888413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="311" mass="33719" checksum="A99FB32AB5AFE543" modified="2025-10-08" version="1">MNDSGEIVGMVDVLKLTYATLEQINTMSSGDSEGPAWNKFWMSLDHETESMVSAEGSAMHHGTNLGSRIMSPDMTRDRINDSLAPNDSASHVGIDSPPHSMLGDTPAAQMSPADIPFPFKFKAPSGRVHRLQVIASQGIETFIANVSDKLGADVDMIGGIPMVEDGKVDGTGCALSYLDDEGDTISITTDNDLLEAIIMARSRRQDKVELFVHDPDHAPSPIHESPPAPAPAPAPSVRERRKHYDTSETETEDEEHGRRSRRSRGHHRHRHAAVQDQVIAGVPNELLLPGAIVALSVVIVGVFTISRLTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJK1</accession>
    <name>A0ABR3YJK1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Poly [ADP-ribose] polymerase</fullName>
            <shortName evidence="9">PARP</shortName>
            <ecNumber evidence="9">2.4.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Cpir12675_006200</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>NAD(+) + (ADP-D-ribosyl)n-acceptor = nicotinamide + (ADP-D-ribosyl)n+1-acceptor + H(+).</text>
            <dbReference type="EC" id="2.4.2.30"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the ARTD/PARP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.-" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000264">
        <property type="protein sequence ID" value="KAL1888363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01437">
        <property type="entry name" value="parp_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07997">
        <property type="entry name" value="WGR_PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.142.10">
        <property type="entry name" value="Poly(ADP-ribose) polymerase, regulatory domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.140.10">
        <property type="entry name" value="WGR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050800">
        <property type="entry name" value="ARTD/PARP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012317">
        <property type="entry name" value="Poly(ADP-ribose)pol_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004102">
        <property type="entry name" value="Poly(ADP-ribose)pol_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036616">
        <property type="entry name" value="Poly(ADP-ribose)pol_reg_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036930">
        <property type="entry name" value="WGR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008893">
        <property type="entry name" value="WGR_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10459">
        <property type="entry name" value="DNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10459:SF60">
        <property type="entry name" value="POLY [ADP-RIBOSE] POLYMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00644">
        <property type="entry name" value="PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02877">
        <property type="entry name" value="PARP_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05406">
        <property type="entry name" value="WGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00773">
        <property type="entry name" value="WGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47587">
        <property type="entry name" value="Domain of poly(ADP-ribose) polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142921">
        <property type="entry name" value="WGR domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51060">
        <property type="entry name" value="PARP_ALPHA_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51059">
        <property type="entry name" value="PARP_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51977">
        <property type="entry name" value="WGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5 9" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BRCT" evidence="11">
        <location>
            <begin position="27"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="WGR" evidence="14">
        <location>
            <begin position="235"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="PARP alpha-helical" evidence="13">
        <location>
            <begin position="362"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="PARP catalytic" evidence="12">
        <location>
            <begin position="497"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="122"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="334"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="180"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="354"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1888363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="736" mass="81205" checksum="25FAE850535C3828" modified="2025-10-08" version="1">MSTRSRSAATAAALNSACQAVTLAGPKRHTVFEGCAVAISGVFPGYSHSTIETLIKDLGGTITKSVTRTTTHLVTTQHDFDNSSIKVQAAVSKGLPVVSLEWVVKASDELVRQREAKFEIGATSASHGAADGRCTPPPVQAPETRPKSPSTPTGTPEKKRGSPDAKTVVESPRKKRARTTKKDTTKEDLGAKGKSEQKPAAEVEQRKEKEVLADGQIAKSDKLVVPLDNPAAFPGGRVYIDQDGLIYDASLNQTNASNNNNKFYRLQIIETGNNNFTAWFRWGRVGESGQFKRIDNSLERCLREFKSKFKSKSGYPYPETGLPKPGSYVFVEKSYEPDDDDEDSKAVRQVKNNSDSDSKEPESKLERPIQQLVELIFNTKYFTDTMKAMNYDATKLPLGKLSKNTITRGFETLKRLAEVLNDQPQAINEFQGNKNNAIEYLSNSYYSVIPHAFGRNRPPIINSGPLLKCEVDMLESLSDMKVAEDIMKVAKAKSTVHHLDHAFEGLNLKEITTLDPESSEFLHLSRYLHVTRGSTHSVQYDVQQIFRIERPGEYERFENGPFRKGSGDGNSKSERRLLWHGSRCTNFGGILSQGLRIAPPEAPVSGYMFGKGIYLADMSSKSANYCFAHASGGHALLLLCEAELGPMQELTCASYNAGETAAQKGMGSTWGHGLTAPPVWKDAGHVHPSLVGVRMPDTDAPPTPTNLPQACLLYNEFIVYNTAQVRLRYLFRVRMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK07</accession>
    <name>A0ABR3YK07_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_006202</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000264">
        <property type="protein sequence ID" value="KAL1888365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF3">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="98"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1888365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="240" mass="27008" checksum="7998B6364C237803" modified="2025-10-08" version="1">MAPSTIWLATGYEMPLVGFGIWKVTREATADTVYNGIRRAIADGLVKHEDLSIATKLWNNYHKQYFDLYLIHFPVALKYIDPAVHQFPLLYDVLNYSRRPISTLQIEHHPFLVQPNPIALAQESGIAVTGYLSFGPQSFLEIPIFKQKTNNVTLLEHPTIIAIAAARSKTPAQVFVRWATQCNIAVTPKSNNVKRLPQNLDVLSFGLTAEEIAHISGFDIGLQFNDPAFYLNNQSLRIFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKF6</accession>
    <name>A0ABR3YKF6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytoplasmic glyoxalase II</fullName>
            <ecNumber evidence="3">3.1.2.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">GLO2_2</name>
        <name evidence="3" type="ORF">Cpir12675_006032</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.6" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000243">
        <property type="protein sequence ID" value="KAL1888805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004416">
        <property type="term" value="F:hydroxyacylglutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050145">
        <property type="entry name" value="Centrin_CML-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23050">
        <property type="entry name" value="CALCIUM BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="213" mass="23140" checksum="766D9881087F7078" modified="2025-10-08" version="1">MGKERGWLTGSCATPKCADITGENTTGAPRQRLSKLAKEHNVTAQEESEIREAFSLFSEPMKGEKDGVIPTPDVRAAMVALGIPPRDGDELAEFLSILDPDNEGFASFEPFFAICALKFHARDSDKDTHSNELDEAFALFTNTYSAGAGAGGDHEDGRITVAHLKRVAALLKEDVSDDLLRDMVLEANRGAGISAGVQKEEFDNVMRRAGVWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKX2</accession>
    <name>A0ABR3YKX2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006048</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000245">
        <property type="protein sequence ID" value="KAL1888764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046421263" evidence="2">
        <location>
            <begin position="20"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="210" mass="24150" checksum="B68086F1140213A9" modified="2025-10-08" version="1">MHFFGLLSLSFLLLVGVNAGSLEQHGYTFEKFSDGYCTVHSDYYGHGTEPLNQFTINVQEKSMIIHTMDNMLEDPHSGQMSLYQILAAVCKEYGLKPDGMNMIAMEFPKSGYEKRGLDNYRRLHQDELNDDQYIDATISRNMIEEWSYFSSSTLYSSIQTMLVWSRIAEISIEESETSCQLFYHIKSDNSGGDVEDEDDNRDGEDDDEYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLQ3</accession>
    <name>A0ABR3YLQ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">DBF2</name>
        <name evidence="14" type="ORF">Cpir12675_005851</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000223">
        <property type="protein sequence ID" value="KAL1889285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21776">
        <property type="entry name" value="MobB_Sid2p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05600">
        <property type="entry name" value="STKc_Sid2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF417">
        <property type="entry name" value="CELL CYCLE PROTEIN KINASE DBF2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="305"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="13">
        <location>
            <begin position="609"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="684"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1889285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="728" mass="82300" checksum="F2AE93E826CDB0F4" modified="2025-10-08" version="1">MGSFFQNPNHRGGDDGIEIIRPITPSSKNIFDDGNDGDVQMTNNNFVNPISTPQGSPSKKTIPPGSNDLPVAFEASLKINNMTIFDSPTKPISTSTRIPIASSTSADGLPLKTNMSFDTSMGNSGIGTESLLNTSIAEENVAHGRAPMSTTTANKSVRQEILTPSSGTKSALAAPENFHKNHAALSRHEMYHREHKDQQKEHGTRHQPIKKFNTSRGLTPEELEILKKPKVRRLVNVTQLYFLDYYFDLLTYVGSRQGRLNAFLSEVPHPPKTDETTYRQMWSKYTGRERAALRKRRVRLRHGDFQILTQVGQGGYGQVFLAQKKDTREVCALKVMSKKLLFKLDEVRHVLTERDILTTAKSEWLVRLLYSFQDDQSIYLAMEFVPGGDFRTLLNNTGVLSNRHARFYIAEMFCAVDALHQLGYIHRDLKPENFLIDSQGHVKLTDFGLAAGMLAPAKIESMRVRLEKASETPVPFGKPMDQRTIAERREGYRSMRDKDYNYAKSIVGSPDYMAPEVLRGEQYDFTVDYWSLGCMLFEALTGFPPFAGSTADETWRNLKHWKDVLKRPVWEDPSYFLSNRTWNFITTAINSRQERFANIQAIFNHQYFAEVDWDNLRETRAPFIPELDSETDAGYFDDFTNEADMAKYKEVHDKQTALEGLAEREEEMAKALFVGFTFRHRKTTADEGHSGASSSPRKPIPFDNAPKPGSGSHTSGSGDFSMDFGTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YM13</accession>
    <name>A0ABR3YM13_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sm protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">smb1</name>
        <name evidence="13" type="ORF">Cpir12675_006026</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the snRNP SmB/SmN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000242">
        <property type="protein sequence ID" value="KAL1888851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01717">
        <property type="entry name" value="Sm_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050914">
        <property type="entry name" value="snRNP_SmB/NAA38-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701:SF0">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Sm" evidence="12">
        <location>
            <begin position="6"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="110"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="110"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="142"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="155"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="171"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1888851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="203" mass="20928" checksum="428D94074E7D8920" modified="2025-10-08" version="1">MSTSMNKQGKMAGYINWRMRVTLNDGRQMTGQMLAFDKHMNLVLADTEEFRRYKHKNEGANNTVETEEKRTLGLIILRGAQIISLSVESPPPADASARLGKTASGLTTTLAAGPGVARPAGRGAPMAPSNLAGPAPGVGGAAPPPGLPSFPPAPGFAGRGAHPPGFHAGFPAPPNFPGVPPFSGAPPGFTGGAPSRFDPSARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN87</accession>
    <name>A0ABR3YN87_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006019</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000242">
        <property type="protein sequence ID" value="KAL1888844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050817">
        <property type="entry name" value="DjlA_DnaK_co-chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24074">
        <property type="entry name" value="CO-CHAPERONE PROTEIN DJLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="8"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="103"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="251" mass="27134" checksum="0938F2EBDD1395D5" modified="2025-10-08" version="1">MSSRAPPDYYAILEIPENASTQKIRDAYKKAALKTHPDRVAADHPERPARTRKFQLVNDAYYTLSDPSRRREYDAQRRLFQRPGAPHGSASAKPDPFDDPFAEFDSASPPPFSSSSSSSTSTPFSWAWNFFSGGSSAADQEKARAKAEETQFADVFEEMLHDEGLDANGEKTNNGGRFWGAVGGVSGGALGFIIGNFPGLVMGAAAGNRLGAVRDDKGKSVYEVFQDLPAHDKSRLLATLAAKVLSQSVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP57</accession>
    <name>A0ABR3YP57_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_005579</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000198">
        <property type="protein sequence ID" value="KAL1890013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13391">
        <property type="entry name" value="HNH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="HNH nuclease" evidence="3">
        <location>
            <begin position="165"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1890013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="355" mass="40024" checksum="4BB432D34E9E6191" modified="2025-10-08" version="1">MEDVPAHSIPMHQIEQLPHSQQKLLVSIIMLVLGFFQSRGGVNIVIRFERAMRRCQDSLERSWPTFIDRILERQSLWEIWTGMGNVEPFGIAIAMTADWDVIRRLPIEALCERFDCTFDRCRMWFCRPVGSAQSASNSTTATPRATRSGYQSTIKDTRRRDGDTCVVSGLQGPVEVCHIVPSSINGQKLAIFKEFVRGFCPDLLPRVQQLFPGSNTAIAENLMCLTPTLHSFWGAGLFALEPVSSSSTLVTVRFWWMHDLLRQITVDLPRAIPGRRRFYDSRSRLEILTGAILQFRSRQGIPAPDFTLLKVQYLMQIMGVLCGAAEPDEDGQEEEDGEVDSLQTESGILAMQGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YPH4</accession>
    <name>A0ABR3YPH4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">G protein subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">STE4</name>
        <name evidence="7" type="ORF">Cpir12675_005478</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat G protein beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000189">
        <property type="protein sequence ID" value="KAL1890259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016346">
        <property type="entry name" value="G-protein_beta_1-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001632">
        <property type="entry name" value="WD40_G-protein_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19850">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25391">
        <property type="entry name" value="WD40_Gbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002394">
        <property type="entry name" value="GN-bd_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00319">
        <property type="entry name" value="GPROTEINB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0807">Transducer</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="65"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="195"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="238"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="289"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="324"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1890259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="357" mass="39401" checksum="F689F97C7C26B1D5" modified="2025-10-08" version="1">MNSHSDVSPEALQSRIQAARRDAEALKDRIKRKKDELADTTLRSISSQAHDPIPRGQLMKSKRSLKGHLAKIYAMHWSTDRRHLVSASQDGKLIIWDAYTTNKVHAIPLRSSWVMTCAYSPSGNFVACGGLDNICSIYNLNQQRDGPTRVARELSGHAGYLSCCRFVNDKTIITSSGDMTCMKWNIETGQKEVEFADHLGDVMSISLNPTNQNTFVSGACDAFAKMWDIRAGKAVQTFAGHESDINAIHFFPDGHSFVTGSDDATCRLFDIRADRELNLYGSESILCGITSVATSVSGRLLFAGYDDFECKVWDVTRGEKVGSLVGHENRVSCLGVSNDGISLCTGSWDSQLKIWAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YQP7</accession>
    <name>A0ABR3YQP7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005273</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000175">
        <property type="protein sequence ID" value="KAL1890693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="597"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="709"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="601"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="717"/>
            <end position="730"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="780" mass="87031" checksum="0164E267054B5364" modified="2025-10-08" version="1">MTCDVLTPTTPIDSIITYSNDAHNTSRIPAPPSAQLPPPRAIRRKPVGSRPTVLNPSRTMSLSLRRNLTRDPSIVYPGPLDHDSRVELQMSSPSLSAANIGRQNCTHPEMVRYWSATDLCSHCMRPGAFGWLYRCCSDRNIMIEANMDNAKHDCHIFDKTGRSMEHMIKPRSKTVLTRTRKFDVLGEISNQEYSRYSPSQLATLVGQRSEVPTSFIPKATHIYLHSPIEKFVLTRMKYMQVLEAASQDFQRPHISKGLLDPTPHIPNFATECKYKCCPNCRPSFKDHAFLPLDAIMNDEVPATAVTGFGFHLLGARPVANAKILHSIGTRTSSRGEFEEEVGANFELVLKEPEPPFLPNPDPISDSADFDSLDLHLQPDTEALVVGLLRQPKEELKVDYPGSNRVDSVGMGLAFISRTISTTEDELPDRHEESRSSIYNETLPYPMTDEEVDGDDVNRNVSATDGTFTTYDFNASNFEYLAPETESCCVMPSPLHLPTKREREITLTIADDWNKTINNFEVDASLDLRLNLPTDIENYLSWESESESDFDVMTNVSSSASLSDIHCDSENGKCAGEAKILEPSSLRDSRLEPVPRLAYRGQSQSQSQSQRESQSQSQSRIQSHCQIQGQDQDQDQDQDQSQSQHQHQLKRKPLPLSSVKGKPTMPVSQLKPPGLLVPVQRKVPLYTSTLPTSSSRQRTTGIPVPVDRKKLAGTSERPMGHEHLKTGDSRSKSSSTTGCSPNRASQSRIPRLSPIRMRVDARPRASSPTVVLSIKLESMGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRE0</accession>
    <name>A0ABR3YRE0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Smr domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005585</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000199">
        <property type="protein sequence ID" value="KAL1889939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013899">
        <property type="entry name" value="DUF1771"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002625">
        <property type="entry name" value="Smr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036063">
        <property type="entry name" value="Smr_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053020">
        <property type="entry name" value="Smr_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47417">
        <property type="entry name" value="SMR DOMAIN-CONTAINING PROTEIN YPL199C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47417:SF1">
        <property type="entry name" value="SMR DOMAIN-CONTAINING PROTEIN YPL199C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08590">
        <property type="entry name" value="DUF1771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01713">
        <property type="entry name" value="Smr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01162">
        <property type="entry name" value="DUF1771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00463">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160443">
        <property type="entry name" value="SMR domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50828">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Smr" evidence="2">
        <location>
            <begin position="98"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1889939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="224" mass="25376" checksum="BEC230664F1CA4B7" modified="2025-10-08" version="1">MSVQMENRRQRAFHHDQDGEIEAEYDRLRDLAHGETAKRNQCFQQSREAYENGDGAAAKELSNKGKRHAAKMDDYNRQASEFILRENNAPGRIDDDEIDLHGQYVDEAERIVEERIGADRAAGRARLCIIVGKGIHSNKNVPKIKPAVEQILDRMGLEYHTDEHNAGRIIVKLNDGGYVPPQQPHNHGQGPHYQEPSHGNQQPESTDLLGALFSYVQKQCCNIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRI5</accession>
    <name>A0ABR3YRI5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glucan 4-alpha-glucosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000167">
        <property type="protein sequence ID" value="KAL1890926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="485"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="224"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="538" mass="57972" checksum="9A40EB31D9BD6090" modified="2025-10-08" version="1">MNAATIQQQQPLQMQTPAPRVLRSKLSLNTSLPVTNRKSSLSHTAAMATQPLSPTALTALNTLSNKHVALSTSPQDAFLPQSEFAIPMTAINTKAQTPYIINTYPETPMTYQQISPAAPQTAICLPNTMTFTPPLSAGPAEQRSVFTFTDASKTYPKLSINTQINPVGTHSPPQPSPPLYPRRVSADDVSSASLPPSHTPHHVRAGSLPYTHPRALHSILRNSPLPSAAQPQSQSQERRPSNRPPKHVGYNSPLEQTIVNRKYTVSHIDLLVADCSPSSPSMPDSLGCDTPIDPFTSNETRNGGMTPGPFEEMRRRIAGLAAISSPATSRLAAPTSDANTATTPIVPKRREKKRQWRWTIGQDDETDLADEEISGALVALRAAEEQTQKKARVLATAVNPEAGLNEPQLAVTEPTTPCPLAAPIQLQIPAPKRRRPVLSCSSTKSDLAKQTSTACLTAPILIGSQDTEMSDASSSYSVFESSMTGIDTDTDIDTEGDSGAEMEGKTPVTWSRAYSEETEEQPWSGRQDGLIMLPVLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YS54</accession>
    <name>A0ABR3YS54_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protamine P1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000168">
        <property type="protein sequence ID" value="KAL1890912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="674"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1045"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1197"/>
            <end position="1308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1403"/>
            <end position="1426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1226"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1242"/>
            <end position="1251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1273"/>
            <end position="1282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1294"/>
            <end position="1304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1576" mass="171336" checksum="F83F0AD2330E716E" modified="2025-10-08" version="1">MKRPLLPLKAPQARPRQQQYSEQSRQRRLQSIQAAIHDDEIPFIYAASLTPPFQNPWDSLTHSQAASKAKSNGVSCSISSTSTPSITDDPSTKSSREQQSSTYSSQTNRYSNSDEDILSLETAACRSASSNRRGGHGRHVREDSPSTNLIWNARTPQTIRRLPMTPSKRFNTADALLEDELASPPDRHGSPALLIRRGNSSVVRIGRSPGVRAVKSPSNFQRSLQTQSDSSDDELATGDMNTSKVKTPRKHVAHALQSRDSHAQASGHIGTTLRRRGRSFTRKGSYGIPDILEKESLSGRRLELSNGSLGSSHVTLRTDETDMSSLLAVSQESEESKTQRDSSVASCRRYRRKNKKTSPTATSILHTRFSAYKQSLEVSKDDSPTSNNDEDTGYSPLTQLKNEVHHSCQNSRLPVIRPSNSLEAAPISQVDTLLSDTLPSHGLEEPLEPHEMVVIDVDAIELRIGENTTVMPESSQTWVKEESISDSSRKTVGDAAQFSHIIAQYPVPSEISAEDEYELSQGSETIMLKSPRLSRHVDNLDCSTIERVDCEHSATPDIIHHTSAVERTPSLKSSNTPVLEEPISISVSSTDAGNVFESRQQLLNALVIRSSSIDTPKGEGHLQARRNSADSGVNLPMPAEVRLGGLIEDVTIDLEGMADMSDVVISSPLAEPSMSIPLRRPQRKRKRSAGSGQLLIRNASSSDLGISPSKEPRDLSMHCPVPQDRQSRHKLITLHPEEILSGSHEAEPSSLSFPMYSWPQNDKGQATPIQDEKTAWSSQIAIRSSPRPSPLRKRVKRGSFASVKCEVIANTSNKEAPDNIEVAASQQDIFYTHEPDMEATEDFVIEDTILAETKTTHKVDFIKREVRYAEHLLQPRNLGTDQANVDDLSTHKVSLACDDVISEVGLSTPQKSPINVEVTITSPLEVSQTPREKNTSTAAAGTGASTIFATPKYSTDFCNKTRETETEPCPSGEIPPSCQLELTTKDDTGSPSLANCLQQPQLNSDAKLSTCSQSGPQNGHATALVAISTIAPNITNIDTVYDTAAVTPEPSTPPPRPPKTHSPSRSTPDTILSPSTLSKRIALKEADESNVYDFPDSPDTNAHMLILQHSRKAHSQLKSRSQARTMVPLPQDATDGRLPPSSLHVGATSASSSFVPPETPATTARTRIVDTHVSAATVAAAGEGKQRYRHEGVELTSPWMDEPSSVNLGFGSQKDSLVPQIPGPSQLPTDYSTPTPLEKNPWTMQDTNPASATLPRWHFSSASATQPEGGPDSSASPTSIHTSSRRSTRPATLRNGSRPPSRTASPLARRAHIMDLLPSARSSDAATVQPGDDFVCRSFASFMTPTPRSDRSAMAYSSGGILKNRHTASQTPARIFRRSRKRVTWSPTLGSTAIFTVATGRCRKRQASPPPQAVVGDTEDDGEPTPALLAKHLDAIKKRKSPSDRLLPSASQRVPASQPVDAMALTFLLAENDVIPGSQADTESYSEIFRSNAEAQSNAVEEQDETVADSTDKQAVPDKTAALSAFSMPDDLEDSFMAEAEPDADDVDYVMDNLEDFLGMPFSVDDEIKKQAQLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSC2</accession>
    <name>A0ABR3YSC2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">39S ribosomal protein L16, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">mrpl16</name>
        <name evidence="6" type="ORF">Cpir12675_005039</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000158">
        <property type="protein sequence ID" value="KAL1891249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="entry name" value="Ribosomal protein L10e/L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047873">
        <property type="entry name" value="Ribosomal_uL16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000114">
        <property type="entry name" value="Ribosomal_uL16_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020798">
        <property type="entry name" value="Ribosomal_uL16_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_uL16_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_uL16_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01164">
        <property type="entry name" value="rplP_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220">
        <property type="entry name" value="50S/60S RIBOSOMAL PROTEIN L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220:SF13">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL16M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00060">
        <property type="entry name" value="RIBOSOMALL16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="Ribosomal protein L16p/L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00701">
        <property type="entry name" value="RIBOSOMAL_L16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="224"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="248" mass="27019" checksum="42CBF818A3D779FD" modified="2025-10-08" version="1">MRLSTASVLANALQSLRISPVRPMLATTGATKAAMAPLLPSRNVQAISTTAALMGSWLEPNLDRTKKMMKGRPRVATGGSTKGTTVIWGDYGLRMVDKHRRISAKQLKNAEDTIKNRLRGTKYRLYKRVACNVGVYISGNEIRMGKGKGGFDHWACRMAVNQVAFEIRGLLHEKVIRDAFRLAGSKLPGQWELIHKDAAPVVGMTKLENGLTLEDLKRPWKKLEDSASTSSSSASPTNSPTTSAATSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSS3</accession>
    <name>A0ABR3YSS3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">U6 snRNP-associated protein Lsm7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">lsm7</name>
        <name evidence="11" type="ORF">Cpir12675_005172</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000166">
        <property type="protein sequence ID" value="KAL1890982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01729">
        <property type="entry name" value="LSm7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017132">
        <property type="entry name" value="Lsm7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044641">
        <property type="entry name" value="Lsm7/SmG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553:SF5">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="50"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="35"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1890982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="137" mass="14847" checksum="02D3A38842FC46F4" modified="2025-10-08" version="1">MADRGNHTRGGGRGGYRGDYRGGRGGSGGGGGGYHHGDREQQPREQKKRDNILDLAKYMDKPIRVKFTGGREVVGTLKGYDALMNLVLDEAKETMSDENGNETERQLGLLVARGTLLVLVSPLDGSEAIENPFLSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSU2</accession>
    <name>A0ABR3YSU2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Meiotically up-regulated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Cpir12675_005191</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000167">
        <property type="protein sequence ID" value="KAL1890925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04041">
        <property type="entry name" value="C2A_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04052">
        <property type="entry name" value="C2B_Tricalbin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21676">
        <property type="entry name" value="SMP_Mug190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057349">
        <property type="entry name" value="C2_Mug190_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037767">
        <property type="entry name" value="C2A_Mug190-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037765">
        <property type="entry name" value="C2B_Tricalbin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47348">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 190 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47348:SF3">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 190 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25331">
        <property type="entry name" value="C2_Mug190_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25669">
        <property type="entry name" value="SMP_MUG190-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="203"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="225"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="398"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="14">
        <location>
            <begin position="270"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="496"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="851"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="662"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="785"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="889"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1229"/>
            <end position="1333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1377"/>
            <end position="1431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="662"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="791"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="895"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1231"/>
            <end position="1241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1251"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1311"/>
            <end position="1331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1377"/>
            <end position="1414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1890925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1494" mass="165228" checksum="A5A33AB9FA302429" modified="2025-10-08" version="1">MEATNRLPASQPYSGRNRIPNISEFMQRLDQNKGQRDAEIDNSDQKITPSKPKRTILSSFTQNPNVVQAPEDDEVSVEVPVEGEAHAHVPVKRKKKGWRTVRDPVTGKDVQIQDISMDYKTVVDDPQLSVPNENLGRPTTVPMSSSMSGEEYRHAQDITAPPDPIELGSTSDVPIRSEKTSILFYKTPSISYEPMFELLEMRASFLAVGLFFGISVFGSMFGGRIWAMTLLGVFVASAVFLWVKDLIRSGRDREWESERERGEMATANLIPESAEWMNSMLGLFWGLINPEMFAGVADTIEDVMVASVPGIIENVRVADISQGSNPIRVLSLRSLPDNHMQDIKSELHSQNVKSMDPEELAAMEQSGAFYNLEASVAYHAKPSGGDVSSKAKNMGMRLIFYLGIRGLFGVPLPVWVELVGLVATVRMRVQLTPDPPFLKTLTITLMGIPKVQAGCTPMIERGVNILNLPLISNFVNWAIKTAASMYVAPKSLTLDIASMLSGDDIMRDTTAIGVIYIRIRRGIDLSKQDHRGSSGGGSDPYVTVSWSKFSKPLFCTRVIQDYLNPIFEESCGLLVTPDTINAGERISLELWDSDRSSADDIVGKIELSIERLMANPNQMFEHTSSLKGLKAESSMPGQLLWDVGYFEKAPFRESLRLAAEKDMERERQEKKKQMEKIEEEKKNTQEQKGEDQTSGHLTKAAQGHQRHDSKMADMPQSPANAHHPQPQLGDGIVQSANGVTGMGSGHTLPVVGEVDGHQPFQPLVEIPTSNTVAASHIVDSRGIPSPLDVSNAPNSEIHSVGTLNSSSPGLDSAGPSPEAEMNSDSATKPASIPPQSVKADRKAEIAATTSEDEKHAIITPPDPQWPSGILSIAVHQIVGLELVNIKGSAGKRKGREYEPGRPEAGAIKEEQGRTLPSSYCTILVNDELIYKTRTKAVSSQPIFNAGTEQFIRDWRSCIATVTVRDSRNREHDPILGVVPLKIAEILHNSSQITRWYPIDGGIGFGRVRISLLFRSVQLNLPPTLRGWDVGTFEFTSSKMTATSYISKHRPKLRLRTGGSSVAVGREMCTVLDDKGNVEWDISTHGKHDHAVLPGLRLPVRYRYRSPIFIEFWQPRKHSPDAFASVWLKDIADLEENSFDIPIWKCDNQTRLSQNYITEQNLKDVRDLDLEEVGRMRFSGRFSAGTDRDHIRFVTSDSLRETIETWEACYAEGVRSESVNVAIPESAQKLHKAAEREEEKKLRNSMRSSFSHRQEDSEVIPEEKGSDDGGNNNGKNPWIAHDGTDWSRAFGEDPSQLMAGPRAPSSMAMSEGVSSLSSHGYSEPCTRSSISGPHNDVVQAEDNMIGAVDTQKVEYSQSAINTDVVDHAENGFSQKQSLPVFTNAPSSGMPLQSRASLASHDSNDRQGLSSPNQGVRATAEGDLDKESKNPLKLIKSYKSRSRDLHRIERGLMQWKPMRNIRFAKDEAIYAARRVKNLGSLNGRTPDVETEISNNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTC0</accession>
    <name>A0ABR3YTC0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Adenylate kinase</fullName>
            <ecNumber evidence="6">2.7.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP-AMP transphosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">ATP:AMP phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Adenylate kinase cytosolic and mitochondrial</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Adenylate monophosphate kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">ADK1</name>
        <name evidence="9" type="ORF">Cpir12675_005111</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>AMP + ATP = 2 ADP</text>
            <dbReference type="Rhea" id="RHEA:12973"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
            <location evidence="6">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Mitochondrion intermembrane space</location>
        </subcellularLocation>
        <text evidence="6">Predominantly mitochondrial.</text>
    </comment>
    <comment type="domain">
        <text evidence="6">Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the adenylate kinase family. AK2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000163">
        <property type="protein sequence ID" value="KAL1891103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:AMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03168">
        <property type="entry name" value="Adenylate_kinase_AK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006259">
        <property type="entry name" value="Adenyl_kin_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007862">
        <property type="entry name" value="Adenylate_kinase_lid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028587">
        <property type="entry name" value="AK2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01351">
        <property type="entry name" value="adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001381">
        <property type="entry name" value="PRK00279.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF011100">
        <property type="entry name" value="PRK14527.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05191">
        <property type="entry name" value="ADK_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Adenylate kinase active site lid" evidence="8">
        <location>
            <begin position="163"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="NMPbind" evidence="6">
        <location>
            <begin position="65"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="LID" evidence="6">
        <location>
            <begin position="162"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="45"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="92"/>
            <end position="94"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="121"/>
            <end position="124"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="172"/>
            <end position="173"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="250" mass="27564" checksum="75B9EE8424A3F79F" modified="2025-10-08" version="1">MADVEIQRLRSVVESFDGRLKRLEERLAGKPSSETIRMILIGPPGAGKGTQAPKIKEKFSCCHLATGDMLRSQVQKKTALGIEAKKIMDAGGLVSDDIMIGMIKAELENNKECKGGFILDGFPRTVPQAEGLDAMLNERSLKLQHAIELKIDDSLLVARITGRLVHPASGRSYHTTFNPPKEHMKDDITGEPLIQRSDDNAEALKKRLATYHKQTAPVVGYYRKSGIWSGIDASQSPSAVWKDVLNVFKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU07</accession>
    <name>A0ABR3YU07_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tetratricopeptide SHNi-TPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_004929</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000152">
        <property type="protein sequence ID" value="KAL1891557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051730">
        <property type="entry name" value="NASP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019544">
        <property type="entry name" value="Tetratricopeptide_SHNi-TPR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15081:SF1">
        <property type="entry name" value="NUCLEAR AUTOANTIGENIC SPERM PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15081">
        <property type="entry name" value="NUCLEAR AUTOANTIGENIC SPERM PROTEIN NASP -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10516">
        <property type="entry name" value="SHNi-TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="Tetratricopeptide SHNi-TPR" evidence="5">
        <location>
            <begin position="264"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="120"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="441"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="347"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="182"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="459"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="480"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1891557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="506" mass="54435" checksum="8001CC1F4154FB2D" modified="2025-10-08" version="1">MADQPAAAAVTTPELATATEPPQDTNATVEPSTPIPTAEALATADSGDNDPLSQKVTLADLCAKGTALYAQKKYEEAAEQYGKAAELQAEQNGEMNPDNADILFLYGRCVFRLGQERSDVLGGKAPEKKPQSQQKTPKANGAAGSSTLASVPPPEQPLGAMSKESQELLDSKKPLFQFTGDENFEDSDADEDDASDEYGEGDDSGEDDDLAVAFEVLDLARLLFNKKLDQVEEQEATEDESKAVDIAARREDSAFVRHIKERLADVHDLLGEISLENERYTNAITDARESLRYKMQLYPEDSEIIAEAHFKLSLALEFASITTTAGEDDGKTEGTQQIDQVLRDEAVQELEAALKSTKLKLQAKEVDLATMASPEENEVTRAQIADVQDIIADMEQRLIDLRGPPVDLNSALASNPLGGVLGAAMGASAAETQARIEEAKKTARDVSGLVRKKGKPEVETTSAPAVSAPATEAPVVGSKRKAEEDLPAESKEEKRSRTEEPAEDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU83</accession>
    <name>A0ABR3YU83_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004917</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MYG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000151">
        <property type="protein sequence ID" value="KAL1891575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003226">
        <property type="entry name" value="MYG1_exonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11215">
        <property type="entry name" value="METAL DEPENDENT HYDROLASE - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11215:SF1">
        <property type="entry name" value="MYG1 EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03690">
        <property type="entry name" value="MYG1_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="354" mass="39588" checksum="57413918423CA802" modified="2025-10-08" version="1">MSVETAAKRVKLDGPLIGTHNGHFHADEALAVHMLRMLPEYALSSLVRTRDPAVLATCDTVVDVGGEYDAAAKRFDHHQRSFTTTFPGRDTKLSSAGLVFLHFGRALVAQSLRNNGNENISADDPKVEMMWRRIYESFIEALDAHDNGISLYDPAVIASHKIEKRFSNGGFTLGAMVGRLNRNWNDPTPDDPTEAQALEDSHFLRASQRIGEEFEHELKYYTTAWLPARDVVQAAFEKRKEFDPQGRVLVFEGTSAPWKDHLYQLEDGKPSVLYVLYPEKPTHDAKWRVQCVPESADSFQSRKPLPAEWRGFRDEELSKITGIEGGVFVHAAGFIGGNLTFEGAKAMALKALEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUG3</accession>
    <name>A0ABR3YUG3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_004718</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the shaker potassium channel beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000140">
        <property type="protein sequence ID" value="KAL1892029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005399">
        <property type="entry name" value="K_chnl_volt-dep_bsu_KCNAB-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150">
        <property type="entry name" value="HYPERKINETIC, ISOFORM M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150:SF6">
        <property type="entry name" value="VIC POTASSIUM ION CHANNEL, BETA SUBUNIT (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01577">
        <property type="entry name" value="KCNABCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="26"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1892029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="351" mass="39373" checksum="7381D60F81601CA6" modified="2025-10-08" version="1">MAWEEPRKTGMQYRRLGNSGLHVSALGLGGWLTFGGQNENEITFACMKEAYDHGINFFDTAESYAGGNSEIVMGQAIKKFGWKRNDIVVSTKLNYGGANGEVLVNNHGLSRKHIIEGLRSSLQRLDLEYVDIVYAHRPDRLTPMEETVRAFNHVIETKGWALYWGTSEWSADEIAEAAGIARQLGLVPPIVEQPFYNMLHRAKVETEFQRLYSRFGLGLTTFSPLKFGLLSGKYNEATEAPPAESRFAKGDDKFVNYMRGNYGNQAWKDDIEKCRKLKPIADKLGIPQSRLALAWCLKNPNVSSVITGASKPEQVVENCRALEAIILLTSEIMTEIDEIFGKFEPDPARQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUU4</accession>
    <name>A0ABR3YUU4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004727</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000140">
        <property type="protein sequence ID" value="KAL1892038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="277" mass="30874" checksum="63A2E854669E9C5A" modified="2025-10-08" version="1">MRPFTNRSRSITTWSRYSEAQESIYKGVEQPSSVRYDLDSESTHAKPNPFASHHDYDTNDDNDFKVGLTRPRRGSKLSAMKDSTVSTAKNLISNLPTISRSNNSASRRHYTDMHNALPETNREDSQTDQFPPWQLSITATSPGDHHNNPSQPPTFQLNGNSSPRFLGSPSSGQISPCSGKKDMRSRLGSASPTKWIKNRRGRAYSAPNQTYKVPNLADYSAGHEPVPVMTMRKDTQSASTGGKHLQPLETGGYLYARDSYDADRDFGEGETEQRSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVH4</accession>
    <name>A0ABR3YVH4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Calponin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SCP1</name>
        <name evidence="3" type="ORF">Cpir12675_004781</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000144">
        <property type="protein sequence ID" value="KAL1891892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050606">
        <property type="entry name" value="Calponin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003096">
        <property type="entry name" value="SM22_calponin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47385">
        <property type="entry name" value="CALPONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47385:SF14">
        <property type="entry name" value="TRANSGELIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00888">
        <property type="entry name" value="SM22CALPONIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="2">
        <location>
            <begin position="21"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="637"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="167"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="470"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="496"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="534"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="548"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="582"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="640"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1891892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="662" mass="74643" checksum="DEFF9EC5501CAD70" modified="2025-10-08" version="1">MASVSSLDKDLRRLRLEKYTVSSANEVRDWIESSLGEKLLSDDLLESLRDGVALCKLVNLIIPPPGLRFKKSAMPFVQMENISLFLKACQSPPINLLQHDMFLTVDLYEQKDPAQVLQCIVSFSRAAHIINPAKFPNAIGPPVKSRPGGALSPQPTGNPPIRGRAFSNASNASNTSKQSAGTLRTGNIHAGSDRLSPVSPDPTRKVSTWARKDQEGSTSPAWNIAQYGYIGGASQGNLGIAFGGRRQITASGPSVPSLQQKESARKKKAEEEERQKREMEEETKRRQAERAAEEERVRLEEERKWAEETQRARDKERMRQEEEKKRWKEEERQWKITEEKRKQEEAEAERRIADERRRVRSNTRPTSSNSILTDHFLSHYASDSSEPAVATNPSAMTDEVDYRGRVRELEKELEQARQREQEYERERQGRLGIQSSSHDSRQRSKSRNAAPTRPPSRHDSWSRDQREVLTTPKTPTISKPSPLAYHQTTAATKSPRPLPVSPPKPARPAVENMPPTLETSPALAPLNRTDRFLSSHTAPASPPAHQTYSRELDATYERDAEDRRRIESQEKTKAAGWAGKSLLEREMEMERQRQREWESEQQETAKAQRTSDGVDGIGGGIGGRWDVSQFFGYTGGDNLNRTDRGGIGDTRRQIVGGPRPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVK0</accession>
    <name>A0ABR3YVK0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_004556</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000132">
        <property type="protein sequence ID" value="KAL1892403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43329">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="39"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1892403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="340" mass="37382" checksum="324322B1FF0AF24D" modified="2025-10-08" version="1">MADTAVPGLPGAIYKTATVNGNTYRYIYASPKNSNPVDTVLLVHGFPDLAIGWRHQIPKLVSLGLRVIVPDQLGYGGTDAPDALEKYSFKSVSDDLSALVRLEVSSSTAQILLGGHDWGGLVAWRLAEWYPELVKAIFTVCTPYVAPAETFFDIDAIVKSGVAPSFGYQIQFCSGEVEKAANDRDGIRSFLAILFGAQKPGGGLLFSPATGIDLENLRLATKSPLVTATQLNYHADQQARNGLKGALNWYRTRRINFDDERVLPRDRVFKIPALFIQARNDVAIRPEMSRGMDKHFSNLTRAETEAGHWALLQTSGEVNDCIEKWLKNQGLVLEKASARM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YVY2</accession>
    <name>A0ABR3YVY2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutamyl-tRNA amidotransferase complex subunit Gta3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004759</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000142">
        <property type="protein sequence ID" value="KAL1891928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049545">
        <property type="entry name" value="Gta3_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20978">
        <property type="entry name" value="Gta3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamyl-tRNA amidotransferase complex subunit Gta3" evidence="1">
        <location>
            <begin position="65"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="199" mass="21876" checksum="97E46D0611A4528E" modified="2025-10-08" version="1">MSPHRTKALSRLAAPPRFPFSARRNLYYSASLASPPLPSASRRGAISAILSTPTWSTKSLIRPATSSGSISPAQLHHLLRLSALPPPSSPDEEAEMLRVLHAQLGFVQDVQSASSASGLEPLRAIYDETPEAIEEATIGLDQLRALLTEEKPHGYLKRPKRERETAPKIKDVEDWDKLVMAEKKVDRYFVVKGSGESVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW77</accession>
    <name>A0ABR3YW77_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Autophagy protein 16, interacts with Atg12p-Atg5p</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ATG16</name>
        <name evidence="5" type="ORF">Cpir12675_004743</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000141">
        <property type="protein sequence ID" value="KAL1892018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013923">
        <property type="entry name" value="Autophagy-rel_prot_16_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08614">
        <property type="entry name" value="ATG16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Autophagy-related protein 16" evidence="4">
        <location>
            <begin position="14"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="186"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="86"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1892018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="224" mass="25735" checksum="2BA29D2BCE8A2403" modified="2025-10-08" version="1">MSRYLSTRSDWRQDYIRALDETEKRQPDDHGLLDACASLADRIAVLEAENALLSRTPTSTSRTHAKSSTSKATFGDQPALKLQRDLTESLRKNSNYEARLRAAETELDQLRAKTRSDLQSLTQLKSEHAQSTTKTHDLKDELQEKRRLLDHLQDEMITINLQLTVAEKERDSVKAENKQLIQRFLNYKASHQEGPVDDASRSNETPLPERRKRAEHSTRSTRPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWI9</accession>
    <name>A0ABR3YWI9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC1 atypical kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_004623</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000135">
        <property type="protein sequence ID" value="KAL1892267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13969">
        <property type="entry name" value="ADCK1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045307">
        <property type="entry name" value="ADCK1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051130">
        <property type="entry name" value="Mito_struct-func_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173">
        <property type="entry name" value="ABC1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173:SF37">
        <property type="entry name" value="ABC1 FAMILY PROTEIN C10F6.14C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="609"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="4">
        <location>
            <begin position="176"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1892267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="663" mass="75817" checksum="186617F3B488FE76" modified="2025-10-08" version="1">MLQIARSFRSSPPHVVTTGANVTNYCTRHCLHTTPKQPQKLPNSGFEPLRPPSPESLGKPYAARTYATQWRWGRRLLMATAVGGAGYICDRHFFAGGMVRSLRTFALGLVVAADYKLNFRPDPWLAGDPHELHRRNAERLSQLIRTNGGVYLKIGQAIAMQTAILPPEFQAMFARMFDDAPQDSWSDVEAVIREDFGGRSVEEVFGVSFTGGEGKGMMERRARACASVAQVHWARLGDGREVAIKIQKRDIVKQLTFDLWTFKAIAGIYSWAFELPLMSLVPYICERLKLETDFINEATNSRKMRDLVNSEPLLRDRVYIPAIYDDLTTRRVMTAEWIEGVRLHDREIISRPWLDRTRNSTPGVSFPLSAPETSTSRQQLRAQSLNEQLKPARQEWRGKNGQGGLGVSRAEVMRTIVDLFAAQIFRWGVVHCDPHPGNIFVRRLENGKAQVVLIDHGLYVYMQPKFRAEYAQFWKALMTLDKATIMRISRNWGIGSGEVLASATLLRPYQGDDTRRFLDSLKGKSRAERQVLTRERMKRATREFLQDETLMPKELIFIGRNMRIVQGINQSMGSPVNRVKLMGEWASRSFYMQADLTLLAKINYYMRHVMFKVVMVVSDVAFYWFWVRQMLGWGKGMEDEVEERMKEVASGYGVDLQHEVFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWK3</accession>
    <name>A0ABR3YWK3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Actin-related protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ARP6</name>
        <name evidence="2" type="ORF">Cpir12675_004541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000131">
        <property type="protein sequence ID" value="KAL1892427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10210">
        <property type="entry name" value="ASKHA_NBD_Arp6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="457" mass="50736" checksum="74FA82E745B10A2D" modified="2025-10-08" version="1">MAPNRRSQPFRPPPPSQTLVLDNGAYTLKAGLIASSPDSDDTTHLTPRVIPNCLARDRHKKVYVGSEVLSARDYSEMTFRRPVEKGFIVNWESQKEIWDREILGHDKKTGLGVDPAETSLLLGEAPGALPALQTNCDQIVFEEYGFARYCRSQVPTWNAYNDIQAIFQTPKSANASPATPAEIVLVIDSGYSHTHVTPLINGRPLHSAQRRLDIGGRFLTNYLARQLSVRYYDMRNDTHIVNEIKERACFVSADFAADLEASWKGPQGARRPEFTAGSNGVARHYVLPDFHSRMHGEIRPFDVAAHVNPRAQALKAAQASEDIITLRNERFTPPELLFMPSDAGMHCPGIPDMVVQALEALPVGLWPGLLLNIVVVGGNALFDGLVERLQKEITLRMPDECVVRVARPADPIISSWTGGVRFARHPNYEKIAVTKQEYEENGAAWVARKFVAGLNSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWR9</accession>
    <name>A0ABR3YWR9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000125">
        <property type="protein sequence ID" value="KAL1892698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.60">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="182" mass="19669" checksum="DA3A69758D350FC6" modified="2025-10-08" version="1">MTNYTDEELNRNWQPSGRRPQSTIARSFSQELSNLFRIENSVADLDSQVDKRKRIVSLQTEELEALQARLREIQNLEACIRGDAEPLSAGSSSSSSPTVASQQEAHQQKQAQAQAHRDGMSLPPATSPAIHAAASTSPAKFSHKVVVDGHQKQRLSTAGSAMRAPSAGNMPPSPIASDGGYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWU1</accession>
    <name>A0ABR3YWU1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Replication termination factor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rtf2</name>
        <name evidence="3" type="ORF">Cpir12675_004505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the rtf2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000129">
        <property type="protein sequence ID" value="KAL1892535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16653">
        <property type="entry name" value="RING-like_Rtf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006735">
        <property type="entry name" value="Rtf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027799">
        <property type="entry name" value="Rtf2_RING-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12775">
        <property type="entry name" value="PROTEIN C20ORF43 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12775:SF0">
        <property type="entry name" value="REPLICATION TERMINATION FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04641">
        <property type="entry name" value="Rtf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="199"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="234"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="279" mass="30935" checksum="4BC75790FB1F3D7A" modified="2025-10-08" version="1">MGNDGGSIPKRHELVKEAARNPTVSELKATAFESLSHAWTHCQITDEKLDMEGVVSDCQGRLYNYECILQGLMPSSASDEADNEHNNRATFETTGIRSIRDVVRLRFKRGGPNGKGILSCPVSMKEIGSKTKSVYLVPCGHAFAEATIKEIQEEACPECSETFLQRDIIPILPTTEPEILRLNSRMKELRTLGLTHSLKKDKSLGKKKSKKDSADKMEMNSNVVSKTARGAKRKATEDQHRKVDKRISGINNPMAASIASKVLAEQDEQKRRRLAASGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWW8</accession>
    <name>A0ABR3YWW8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peroxin 26</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000132">
        <property type="protein sequence ID" value="KAL1892407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="407"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1892407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="459" mass="51341" checksum="7EDF3617CBB631B2" modified="2025-10-08" version="1">MSMDNPFVAATISSGNDDGFVAAITPLSHAQNVGHSSHISKCYRQASTLFLTRRLPEALSTVLPLVWPRTAPDTNALIEAPPVARASKSTRVKVWSLYLTILNAITELEPQEGKETIGAQDFRMICNKVRDGDIWAEVVKNGYHGVEGDVDAEVVINLYVPMFITTLLLAHSTSQLVNQKRLEAYLSYVDSPSSLANKLDSISQSPKPQHKFRSSARRGGAETPRELNARIKILELYTLHVLLRNDEWETSRAYINASPLLDEERREAFLQALQSLRDEQNEAKLRHENEQNIRRDSLRHEAEEADRRREENEQREQQRLVEERTRRDENTPSLAGSDRSNSTPGFSSRGSMDSDCRITHDSLQVSPGRDKDRNNGQSFPISITGRAGMLVAQIKGMIDGMSRSLDLNVVILLKLATFMAGVLLMLGRRDVRQKVQRIIATGWAKVKATASMGSRVSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXF0</accession>
    <name>A0ABR3YXF0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Molybdate transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000127">
        <property type="protein sequence ID" value="KAL1892586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031563">
        <property type="entry name" value="MOT1/MOT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31970:SF9">
        <property type="entry name" value="MOLYBDATE TRANSPORTER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16983">
        <property type="entry name" value="MFS_MOT1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1892586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="451" mass="46245" checksum="770E3D7B722B2975" modified="2025-10-08" version="1">MPSPAPARATGFLPSVRHAMQYNLAMLRANPLAELSGSLGDLGTLLPLMLALAAQDSISLPGTLVFSGLFNIATGAVFGVPLPVQPMKAIAAAAISHRGDSAPAAVAAAGMAVGALCFVLAASGLLRRAAAAVPVPIVKGIQLGAGLSLVTGPAASLLAPLPWLHPLFDNRLWALSVFVLLLATQLTPRFPSALLAITLGLVLSLMSDPSALPGLHPWLPKPSLTPHFSAGALSMAVGQAPLTLLNSIVAVSALSADLMPHQPAPGVVPLAYSVALMNAIGPWFGCMPVCHGSGGLAAQVRFGARSGASVMILGTLKLVLGLFVGSRLQPLLAAFPRAILGITVLAAGLELARTAASVNRGAADLLEAVGPRRVSRVLGDEERVERWNVMLMTAALGLAFKSDAVGFLAGLACHLSYAVGPRVADWWDVRARVSGSGGFVGRQRERMPLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXF9</accession>
    <name>A0ABR3YXF9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S25</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS25</name>
        <name evidence="6" type="ORF">Cpir12675_004348</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000120">
        <property type="protein sequence ID" value="KAL1892938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.63.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004977">
        <property type="entry name" value="Ribosomal_eS25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12850">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03297">
        <property type="entry name" value="Ribosomal_S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1892938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="94" mass="10775" checksum="4F6763E0B0B28578" modified="2025-10-08" version="1">MAPAAKKQKKKWSKGKVKDKAQHSVYLEKNVSERLHKDVQSYRLVTVATLVDRMKINGSLARKCLKELEEEGLIKPVVLHSKMQIYTRVVSPTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXL3</accession>
    <name>A0ABR3YXL3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Formyl-CoA transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004277</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CoA-transferase III family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000117">
        <property type="protein sequence ID" value="KAL1893086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10540">
        <property type="entry name" value="Crotonobetainyl-coa:carnitine coa-transferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052985">
        <property type="entry name" value="CoA-trans_III_biosynth/detox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003673">
        <property type="entry name" value="CoA-Trfase_fam_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023606">
        <property type="entry name" value="CoA-Trfase_III_dom_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48229:SF1">
        <property type="entry name" value="ALPHA METHYLACYL-COA RACEMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48229">
        <property type="entry name" value="CAIB/BAIF FAMILY ENZYME (AFU_ORTHOLOGUE AFUA_1G05360)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02515">
        <property type="entry name" value="CoA_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89796">
        <property type="entry name" value="CoA-transferase family III (CaiB/BaiF)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="558" mass="61944" checksum="9714446B496601FD" modified="2025-10-08" version="1">MTHLEESADAYNVQQEAQRFFIERLIGDKKLNLHSDIIKAASYVRFSGDDSQPFIPSPFKMTESMSALFALVVSSANAVASSRYGIPLQNTGVNTDLASLFALSIVLPFINGVHFIQHKALMDELAKGEIYDMAKPIHRASTGLYKTLDDRWYFLHGSMNAGPTMRMVEVPEQDGLTYDEAMRVYADKVAQRTAASLEQQANTDFKQAGVTCLTPEEFFSSEHGKIMATEPLWNRNEVPIPAPVPWPEQSSAEAGGAECGFRPLAGIKVIDFSRVVAAPVISKILAVLGADVLKIGNLQLPDVTVLLPDLSTGKRDASVDMKTAEGKAIFEKLVQEADVIVDGYRPGVLGRLGFSAERLREINPSIVVARENCYGWKGPLKDRSGWQQISDCMVGISWLQGQFLGLDEPVLPLLPNSDYQTGLIGAAAILEALLIRSREPVTFDINVSLTQYNIWYYRLGQYNKLQQKALLSRNEGFMARHNEDMVALLFKVYAQLKKVRPEIFTLPENFVHMSGKEWGLEEGEDFQILAPPFSMEVSGLGYAVPSGCRGRSKPKWRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YY08</accession>
    <name>A0ABR3YY08_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Spindle pole body protein ppc89</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_004264</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000116">
        <property type="protein sequence ID" value="KAL1893118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051756">
        <property type="entry name" value="Centrosomal_MT-associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024957">
        <property type="entry name" value="Cep57_MT-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025925">
        <property type="entry name" value="PPC89_CLD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19336:SF9">
        <property type="entry name" value="SPINDLE POLE BODY PROTEIN PPC89"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19336">
        <property type="entry name" value="UNCHARACTERIZED DUF1167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14197">
        <property type="entry name" value="Cep57_CLD_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06657">
        <property type="entry name" value="Cep57_MT_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPC89 centrosome localisation" evidence="7">
        <location>
            <begin position="436"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="PPC89 centrosome localisation" evidence="7">
        <location>
            <begin position="628"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="domain" description="Cep57 centrosome microtubule-binding" evidence="6">
        <location>
            <begin position="1059"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="85"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="255"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="531"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="793"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="956"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="376"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="611"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="48"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="143"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="153"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="166"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="274"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="531"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="581"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="825"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="873"/>
            <end position="882"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1180" mass="132503" checksum="3D737827DE011E6E" modified="2025-10-08" version="1">MDVESPETRYRSRILREMNANRENPFNSPPSSTGSHGTLDPTMTSIITDHEGETTRRLNEDIARITGNGRKPSIDWEAIHKKWPDFYPKPKPLHPESRKYASKNTPSAAATAPSSPASGLASETKENRPPKAAKKRFSMDDFTLSSFTGSSRTRAEMQPRVDSDSDNSSVLNLSPDRLSLPPPSRFPHQPQNRSPLAREHTRSPSTPNDSPTPVRRMSLPAALCKQQFHASTEQSPQKVQRKLNFAQHVLSKEVKAATKQKNKKQQSTPADYLPSSQRTSNSAFHNDNETMGSTSRSFVLPDVSNLGDFVSGTLRFDGTIKNGIPILVKNGQVVDVGDQQQTRRNSHTAIGGLKAPEDEKNIFVSMDMIRDEVVALQEHDEMVQDYAEDLQKEVEELQAQIEVLKGRSFGNTMNLEKNSDEKVSVNETLLEEKKQLEEEVIVLRFRLQEVTKKLEVVEAEKQSAVAERDRAMKKLQGACENINDLMGRLDMSQHELHVTQKQLDATLDVRQTDESLASELKVLKEANKKLRAENEPMRREAQSLRENSNDLRQENESIKQEVKSLRQDNSSLRKENGSLMKENQSLRSSSRQVMTENEELRKSIDLAKGEVSGARVELERLHEVIAKLEEEKAVYQQDNHSLERHNDKYFSDNKTLRLQASNFERNLQDLNSDNEKLKQEVEYLKTHLEHIRQTAVVRETRDMTGTAGGPTLTRGIDDDNMTSAFFVPDITVHTEDNTVPFESTRTFNRRLLTRRQQLLAQQTQTMDVTEDLKDNTPTQVVDFTASSFKDMETGEVEDNSVDMRPATTKATKTGNTVKFDVPDLTMTSAGDQSQNLATSSTPAANRSSKRRSSIKTTQAPAHKDDTETGSVGFASNDNTRNFSVRLEKDQQDVGENYTGNTKTGKKIHSKKPSNNLEQDFTNMSLGRSHMQNMTQNFTEQFSQRLDTHNTVDFTLHSTTGGMTGNLTRGETRNANKTSSRSVVLDKETCPALSVDARKVFDDLCEHSCRNCNVCSRISAHTNVVSPSELAEGKKRVSVARPIPVSDRISFAAVQHFEEPTMRPSQPPGNALAIVIKALEDESEHLNMELAGLQARYNALDKSLGKRERREVASQLRAIIKRLEAKNDQIYALYDVLEGQKQAGQVMTEEQLETTIMNITGMNVAGVDLSQQLTWEGIRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZI4</accession>
    <name>A0ABR3YZI4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Lysine 2,3-aminomutase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_004070</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000108">
        <property type="protein sequence ID" value="KAL1893462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003739">
        <property type="entry name" value="Lys_aminomutase/Glu_NH3_mut"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00238">
        <property type="entry name" value="KamA family radical SAM protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30538:SF0">
        <property type="entry name" value="L-LYSINE 2,3-AMINOMUTASE AQ_1632-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30538">
        <property type="entry name" value="LYSINE 2,3-AMINOMUTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01070">
        <property type="entry name" value="PLP-dependent"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1893462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="551" mass="61011" checksum="6160EBA55EBE0B22" modified="2025-10-08" version="1">MTGKMAASSIAMAFGASISRRPLIPIRHCRFLSQLTSPVTADIPGPPSSNIEYSYDTISLSPVATNGSKDVPEPTLPQPPALLPLETPKIEVSLPTTVKSPLEHPDQFWRKIPMWKNVGTGEFLNYRWGTANVVQGNPKLLKFLTSTLPLTLPKVPSLPSAPQAPDGATETREELIEDIFAGISAATMAIRMTPYVLSRIDWTNPRQDPVFRQFIPTKSSMLADHPKLTLDSLHETSDSPVKGLVHRYTDRTLFLPTSVCPTYCMFCTRSYAVGANTEQVTKASLKPTRSTWESAFSYIENTTTLRDVVVSGGDSYYLQPDHIDMIGDRLISIPHIRRFRFASRGMAVSPNRILDKSDPWADAIIRVAKKARRAGKHMALHTHFNHPNEISWITEMAARRLHEEGVTVRNQSVLLRGVNDCVKTMGTLIHKLANNNIFPYYVYQCDMVKSIEHLRTPLSTIIDMEACLRGSIAGFLMPQFVIDLPGGGGKRLASTYETYDAATGKYTYLAPSVTGRGKESRIYEYYDPLGTAGAVRGSGLSRLLMQQAPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z176</accession>
    <name>A0ABR3Z176_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_003716</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the APC10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000093">
        <property type="protein sequence ID" value="KAL1894288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08366">
        <property type="entry name" value="APC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016901">
        <property type="entry name" value="APC10/Doc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004939">
        <property type="entry name" value="APC_su10/DOC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12936">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12936:SF0">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03256">
        <property type="entry name" value="ANAPC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01337">
        <property type="entry name" value="APC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51284">
        <property type="entry name" value="DOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="DOC" evidence="7">
        <location>
            <begin position="199"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1894288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="458" mass="50601" checksum="EC7DCAA2C535B5C2" modified="2025-10-08" version="1">MEAGGRRMTRATARGANGRQNNITDITSSGNSLNDLGDRTSNNAANHAPPTATRGSFISRLAATQYLDQEDVGYDHTGLFSNVRTGATQRLDLDEDTELVAVQERESLPAGPATQRLFHQFRAMAQQHNDFTSSSVSLSTLAAATLNSAGRHMSIQEIHEMQDEEIEEEYEENSADGNGVDIEVEDDMHHEEEEEEEEEGEGDEDEFDQEALRDLASHGLKEISNLGRFTVSSQKQGNGVEELRSDDLKLYWQSDGPQPHKLTVYFIKRVSIRTIRFYVNYKEDESYTPTKIVFKSGTGENTLIEFASVDLSTPVGWQDVPIFGCGGGLDGNTLVSYVFQMVILENHQNGKDTHLRGIKIYAQEHEERALGGDGLPAIDMEHMNLTPGFDSRGRPATAIANSWTPMAVIAMTNGETDEPKAEAELAKRKKMAQDAGLDEWISDSLIRGPNSVTSLSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2A0</accession>
    <name>A0ABR3Z2A0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alpha-1,6-mannosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MNN10</name>
        <name evidence="6" type="ORF">Cpir12675_003709</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000092">
        <property type="protein sequence ID" value="KAL1894327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008630">
        <property type="entry name" value="Glyco_trans_34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31306:SF5">
        <property type="entry name" value="ALPHA-1,6-MANNOSYLTRANSFERASE MNN10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31306">
        <property type="entry name" value="ALPHA-1,6-MANNOSYLTRANSFERASE MNN11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05637">
        <property type="entry name" value="Glyco_transf_34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1894327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="439" mass="51666" checksum="ED8CBAFE83753C75" modified="2025-10-08" version="1">MSLSRSPSPAPGGSWSSPGLDVNTSGRSSPNKDSPMWSDSPTMRASPASFNQGFFTRHMRKLSSSLPRFNHEIPYAEREKAERNGHWSPGGGGFLSRLSRRTKSRLMFVLSIIMLVWLWNGTPLYYHFRKNSYLGGGDKFVIVIGSNVGGGVMEWKGAREWAIERDSLRNKKKYVRRFGYNLEIADMKTRKKYAHEWRESWEKVDFIRNAMRKYPHAEWFWWVDLNTYIMEPKVSLQTHLFNNLDKYIYRDINKYNPLNITHPFTEEYLDVEDRSPNGDGKLESVNMILAQDCSGFNLGSFFIRRGPWADRLLDVWWDPVLYEQKHMAWEHKEQDALEQLYMTQPWVRKHVAFVPQRMINSFPTGACGDAEPGDEVHYDQKDRDFLINMAGCEWGRDCWGEMYNYRELSYYLNRSIWERFKEDLVAVMWYKLTGQKVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2E3</accession>
    <name>A0ABR3Z2E3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nuclear SAM-dependent mono-and asymmetric methyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.319</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">HMT1_2</name>
        <name evidence="7" type="ORF">Cpir12675_003529</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.319" evidence="7"/>
    <dbReference type="EMBL" id="JAWDJO010000085">
        <property type="protein sequence ID" value="KAL1894788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035242">
        <property type="term" value="F:protein-arginine omega-N asymmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055135">
        <property type="entry name" value="PRMT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006:SF53">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22528">
        <property type="entry name" value="PRMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51678">
        <property type="entry name" value="SAM_MT_PRMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="5">
        <location>
            <begin position="62"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Protein arginine N-methyltransferase" evidence="6">
        <location>
            <begin position="164"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF22528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1894788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="343" mass="39306" checksum="77602421981519DD" modified="2025-10-08" version="1">MSQMDIDKQKESLESMAHSEQHYFKSYDHHGIHEEMLKDDVRTRSYMNAIVQNRHIFKDKVVLDVGCGTAILSMFAAKAGAKHVIGVDMSSIIFKARQIVEVNGLSDKITLIQGKMEEVELPFPKVDIIISEWMGYFLLYESMLDTVLYARDRYLQPDGLIFPDKATIFIGGIEDGDYKDEKIGFWDNVYGFDYSPLKATALSEPLVDTVEVKAVVTDPTAVLTLDLYKCTTEDLAFSVPFKLAARRDDFIHALVAWFDIDFTACHKKIRFSTGPHTKYTHWKQTVFYLTDVLTVQQGEEVEGVISVKPNERKHRDLDINIEYKLLTEDETRKAEGALEYRMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z387</accession>
    <name>A0ABR3Z387_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome oxidase assembly protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">COA1</name>
        <name evidence="2" type="ORF">Cpir12675_003550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000086">
        <property type="protein sequence ID" value="KAL1894659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014807">
        <property type="entry name" value="Coa1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042432">
        <property type="entry name" value="Coa1_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28523">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28523:SF1">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08695">
        <property type="entry name" value="Coa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1894659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="219" mass="24534" checksum="95BA3267A9C90CF2" modified="2025-10-08" version="1">MLTKALQQRALAQLARNAAVSRPSIWAHTVRQVSSASSTPAPRAGDGPLMERRANRELPDVRSIQFSWFRSLPIFVALIALCSAAIFNYQKMTSSVTNSTLYALRTSPRARAILGNEIYFKQRIPWISGEMNQLHGRINISFSVKGDKGEAVMTFTSYRYTDRGQFETMEWSLTTPDGKRIDLLDGGDPMGSILNTALELDEEDFAIQTRGYRQKPLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3G9</accession>
    <name>A0ABR3Z3G9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003517</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000085">
        <property type="protein sequence ID" value="KAL1894776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="47"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="108"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1894776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="548" mass="60908" checksum="39B41DC47A3EBF4A" modified="2025-10-08" version="1">MSYNASFQQREISPNKPGDEFFDWCRWESDGNPMPRSSPGYSVDTMSSGTSGSSSPRTPSLRSTNGSSSPRYEYGYGYGYGGSGSDQDMADSPDSWGPGNGSGPVYLSPSSASSSSSSASKKTRARRVEDRIKTAKVRDDKACLRCHMRKVPCEVGKCTQCAKFAPAMAQEACIHEGRLRSIGLVSPYFAGEFLAVFYVVHSVCVVRAALPVAAGLNVPSVRESRHAQQQAVVTQIAFESGSTLNINAIQYRHSDGSVTLGLNPSASPSWDQLSMWAGESLVHEAPGTFQSALYLFLMQYVISGPQAPKHDFAVKVFQLLCMFRIWSAPSFLHSGGYPQVDLDNQIRRIARKALSSLERDVIAILDESLGWAKAKSFKTADEKPVLFVCLWLLILMYRQINQAILSGAMTAVKNFEQMRYVSYRLYLALIVFYTGHFYQPASLNPSLEDCNMNIARSHMDALKGSFAAVMDQRLSFISSADMEESNDSFDKYLFHMLVDHEQAKLCAFRKRRSRKKHATQELPVYLPDIDHAVLQQHMNLDIDVAEFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z448</accession>
    <name>A0ABR3Z448_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Band 7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003717</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000093">
        <property type="protein sequence ID" value="KAL1894289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13437">
        <property type="entry name" value="SPFH_alloslipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2090">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043202">
        <property type="entry name" value="Band-7_stomatin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264:SF19">
        <property type="entry name" value="AT06885P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264">
        <property type="entry name" value="BAND 7 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="3">
        <location>
            <begin position="88"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="355" mass="38484" checksum="F227200997186818" modified="2025-10-08" version="1">MTSPTQKQTIPVSPSQASGTGEASLTVGFRSQQPMEVQPPRMQDLQQSYAAVVASDTNPKGWYGYMIDSCGSLIGTCGAIPCCIVCPNPYKNVMQGNVGLVTKFGKFHKAVDPGLVKINPLSENLIQVDVKIQIVEVPQQTCMTKDNVTLTLTSVIYYHVVAPHKAAFGITNVRQALIERTQTTLRHVVGARVLQDVIERREEIAQSIGEIIEDVATGWGVQVESMLIKDILFSQELQESLSMAAQSKRIGESKIIAAKAEVESAKLMRQAADIMSSGPAMQIRYLEAMQAMAKSANSKVIFLPAANQTMPHIQNGSTRREGDSSVHGYEAGFSEFAGSSDGLQSAVNARIIEHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4E8</accession>
    <name>A0ABR3Z4E8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">DRS1</name>
        <name evidence="16" type="ORF">Cpir12675_003371</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000078">
        <property type="protein sequence ID" value="KAL1895142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17947">
        <property type="entry name" value="DEADc_DDX27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="15">
        <location>
            <begin position="262"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="293"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="497"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="724"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="11">
        <location>
            <begin position="262"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="36"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="133"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="183"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="228"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="733"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="794"/>
            <end position="803"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1895142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="803" mass="88387" checksum="13DF5A605670ADAC" modified="2025-10-08" version="1">MAQPVKKRSIDDDFVFTISDNEDADVEEPESAPAPPKKKAKTTKKSKKSKRNSGKDDEGSDDETAEGIWGQNDDDDGAMASDFEFLQGDVEDLREDEFSGWGFDNAKKSMKAESQGVDLEEIIRRRVAKKASENGTVAPTENSSEAKSDDEADNELDLDLDLDDDEDGVLADDAFGMGVQQDGADEEYDDKEASENEEAADDDDDAAASDNDSVATPIEHPDDRDASDSEGEEEEDAEEAAKALAFYEQEAPAAPGQKDTSRSFQAMSLSRPIMRGLAAVGFTKPTPIQGKTIPIALLGKDVVGGAVTGSGKTGAFIVPILERLLYRPKKVPTSRVVVLAPTRELAIQCHSVATKLAAYTDIKFTLAVGGLSLKAQEAELRLRPDVVIATPGRFIDHMRNSASFAVDTVEILVLDEADRMLEDGFADELNEIITTLPKNRQTMLFSATMTASVDRLVSIGMSKPVRLQVDAQNKTATGLVQEFVRLRPGREEKRMGYLVWLCKNVFHERVIVFFRQKKDTHIARIVFGLLGLSCAELHGSMNQTQRIASVENFRDGKVSYLLATDLASRGLDIKGVDIVINYEAPQKPEIYVHRVGRTARAGRRGIACTLAAEPDRKVVKAAVKTAKVQGAKIVSRVIDAAEADKWQVKVDEWAGEIEDIMKEEQMEKEIANVEMQVRKGENILRHEDEIKARPKRTWFESERDKNNAKEVSRLELNGVREALKKKHGANRLSNKDKKKLDSKADRSEGRSWKKGKTERDGKGAVLNLKKVKKPAMKTKDSKKPVGRSGGKSSGKPKGKGGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z508</accession>
    <name>A0ABR3Z508_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vacuolar morphogenesis protein 7-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003369</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000078">
        <property type="protein sequence ID" value="KAL1895140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06897">
        <property type="entry name" value="PX_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15858">
        <property type="entry name" value="SNARE_VAM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF257">
        <property type="entry name" value="VACUOLAR MORPHOGENESIS PROTEIN 7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="2">
        <location>
            <begin position="3"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="1">
        <location>
            <begin position="300"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="364" mass="39411" checksum="38FAA0784FEBE68B" modified="2025-10-08" version="1">MAPPAEISIPSTIVASPNAKPYTLYNITLRLPLRSFVVQKRYSDFAALQTALATAVGTPPPSPLPGKSWIKSTVSSPELTESRRAALETYLRAIAESPDRRWRETSAWRAFLSLPSTSAPSSSVSAGGLINNVAGVGAQDPSTWLDMHREMKMLLQEARNCLSRRDAAVDANNTAATVEAGTGAKRALSKANGLLHTLSEGLSVIQERGRLGDGELRRRRDLLMSAKVEREGLEKLSNTISSTASVARTGAASSSDKMALFGPTSSLAITPRSGRVIGAPVAETDQTRELDNTGVLQLQQQMMQSQDQSLDQLAAIVRRQKDMGLAIKDEVERHVEMLDRVNEDVDRVSGKVRVARNRIKKLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z538</accession>
    <name>A0ABR3Z538_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteophosphoglycan 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_003137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000069">
        <property type="protein sequence ID" value="KAL1895746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028322">
        <property type="entry name" value="PNRC-like_rgn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15365">
        <property type="entry name" value="PNRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1895746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="481" mass="52783" checksum="2B3A156ABEDBFE39" modified="2025-10-08" version="1">MTESSAPKEKRAGRNNNNNKPRSRVNKGRQTAYVSEPEHGFNVGVPITEPPKTPQKTNARHQTPGSQNKNQNLNQSRTQLKQPKNRSRSKNLQTSPLPQNSQAARTRSTSVRQTTPPQSAGLSRSTSTPFAGSTFHASPAPSSLPMPKFLVKKPTTPEAELSQSVSDKSEPSPPSKNINQATPSRPSVASGPLPNGGFAHDSPLEFIFQADRAEKQRAKYTSPQTIESEKKHLEQPHTVPRMASRRPTNPPPSDSPALLSAIFNSVQSSPSVNKVLRSNGGGNLPRNYYQAMASEMDDGYAHQPVGSSFARPFSERLKEIQSPPRADHSQQTSSAPIQAVMHTPPPPQHVLPTPPRASMHTPPHNDSQKISDDASVALKAYLFNIPTPETPSITNINPMKRNGDFSHSPPVHQPNGFHRGYNRHQNQHEMHQDYQRGLEPGFHANLQQKSMSNAYPIMASESLALEDRLRQMLKISPSGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z592</accession>
    <name>A0ABR3Z592_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">20S-pre-rRNA D-site endonuclease NOB1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">nob1</name>
        <name evidence="11" type="ORF">Cpir12675_003073</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
            <location evidence="7">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the NOB1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000067">
        <property type="protein sequence ID" value="KAL1895795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09876">
        <property type="entry name" value="PIN_Nob1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.210.10">
        <property type="entry name" value="Nin one binding (NOB1), Zn-ribbon-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039907">
        <property type="entry name" value="NOB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017117">
        <property type="entry name" value="Nob1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036283">
        <property type="entry name" value="NOB1_Zf-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014881">
        <property type="entry name" value="NOB1_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033411">
        <property type="entry name" value="Ribonuclease_PIN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12814">
        <property type="entry name" value="RNA-BINDING PROTEIN NOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12814:SF2">
        <property type="entry name" value="RNA-BINDING PROTEIN NOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17146">
        <property type="entry name" value="PIN_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08772">
        <property type="entry name" value="Zn_ribbon_NOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037125">
        <property type="entry name" value="D-site_20S_pre-rRNA_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144206">
        <property type="entry name" value="NOB1 zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Ribonuclease PIN" evidence="10">
        <location>
            <begin position="20"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="Nin one binding (NOB1) Zn-ribbon-like" evidence="9">
        <location>
            <begin position="289"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="117"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="412"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="126"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="156"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="194"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="220"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="418"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR037125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1895795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="441" mass="48544" checksum="8BE4483EC1377982" modified="2025-10-08" version="1">MATHIATSTSAATPKTIHSLIIDTGPLIKNDPPISSLMARATQLFIIPSVLDEVRDAHTRTRLQNLLPFLTLRNPKPASVEFIKGFACKTGDLEVLSRPDLHLLALAYEIDCERHGNSDRLRKDPSQTSTNAQNNAPGAETKAETPAVEEGEGEKEEIGEAKAPEPKIPAADDKAEASEEKEQDQATEEAVSTALENLSLEHSNTTKVLAETAADSTTKEEEEEGEASDNEGGWITPSNLKKRIDEEKGSLPSDEVTFMEAALLTTDFAMQNVALRIGLNIMSSSMHRITTVKTFILRCHGCFATTKDMAKHFCPRCGQPTLIRASCTTDANGNFKLFLKRNFQWNNRGNVYSIPKPIHGSSNGKMPKNVSIGGHKGWGRNLILAEDQKEFVKASNDRRRLRQRDLMDDDYLPGILTGERKGSSDRIRVGAGRSINSKKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5T0</accession>
    <name>A0ABR3Z5T0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Uracil-DNA glycosylase</fullName>
            <shortName evidence="5">UDG</shortName>
            <ecNumber evidence="5">3.2.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">UNG1</name>
        <name evidence="9" type="ORF">Cpir12675_003149</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.</text>
            <dbReference type="EC" id="3.2.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.27" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000070">
        <property type="protein sequence ID" value="KAL1895567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd10027">
        <property type="entry name" value="UDG-F1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="entry name" value="Uracil-DNA glycosylase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00148">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002043">
        <property type="entry name" value="UDG_fam1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018085">
        <property type="entry name" value="Ura-DNA_Glyclase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003588">
        <property type="entry name" value="PRK05254.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003589">
        <property type="entry name" value="PRK05254.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003592">
        <property type="entry name" value="PRK05254.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00628">
        <property type="entry name" value="ung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264">
        <property type="entry name" value="URACIL-DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264:SF0">
        <property type="entry name" value="URACIL-DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00987">
        <property type="entry name" value="UreE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="Uracil-DNA glycosylase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00130">
        <property type="entry name" value="U_DNA_GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uracil-DNA glycosylase-like" evidence="8">
        <location>
            <begin position="122"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="303"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="314"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="344"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5 6">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1895567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="407" mass="44897" checksum="96C33AA8A5E4A972" modified="2025-10-08" version="1">MSTLKRKATSALDSEESKKTKPNASITSFFNAKPASTSGGNNASGSAPLPAFNKEKWVQSLTNEQRDLLRLEIETLHVSWLALLKDEIVTEEFLNLKRFLNREVANGRKVFPPREDIYSWSRYTPFNTVKVVILGQDPYHNVNQAHGLAFSVRPPTITPPSLRNMYVCLTNDYPDFVTPPKNNGLLTPWAERGVLMLNTCLTVRAHEANSHANRGWERFTQRIIDLVAQKRQCGVAFMAWGTPAGKRVVKVDQKRHLVLKAVHPSPLSAARGYFTCGHFRKANEWLVTRYGKSGEIDWSLVPSSKIAPPPPPAVTASAASTAAARAETSTQKTGSQGSTPTSKDVGKDASEEVEKTAEKEQEKPNSPEVKIHEDEGDEAKPDAKSAEEPEKVDSPAKAQESDKVDQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z608</accession>
    <name>A0ABR3Z608_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phosphoinositide 5-phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.36</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">syj1</name>
        <name evidence="7" type="ORF">Cpir12675_003204</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the synaptojanin family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.36" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000072">
        <property type="protein sequence ID" value="KAL1895515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004439">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd09090">
        <property type="entry name" value="INPP5c_ScInp51p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046985">
        <property type="entry name" value="IP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200">
        <property type="entry name" value="INOSITOL 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200:SF257">
        <property type="entry name" value="PHOSPHOINOSITIDE 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00128">
        <property type="entry name" value="IPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAC" evidence="6">
        <location>
            <begin position="195"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1016"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1122"/>
            <end position="1403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1062"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1144"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1154"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1185"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1216"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1265"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1322"/>
            <end position="1336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1337"/>
            <end position="1367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1390"/>
            <end position="1401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1895515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1424" mass="156134" checksum="B15ECD23F6A69F14" modified="2025-10-08" version="1">MERAGTWASGLASAPLTAHHDNLCELLIRDHPHRSIAIASSKHVLFFRHSPTTSEAIANGSLSAYRPRAAADTNAVSKCMVELVSRNKSILEDYTPLTHMPIYGTLGLITINQDVFLCVINKASRAAAIRPSESVERIDAVNFYCLSSSLYDEHISAADVWDDDAASVYLQGATARRDYQTYAGIQPEEHPCNELRKLLSNGSFYYSTDFDLTNRLQDRPVNINSYNIDNFDESFLWNSFMIKPLVEFRSHLLPETRRALDESHILTSIIRGYCGTMTIPQTMAPLRGSAASGPASYLSVISRLSCRRAGTRFNARGIDDDGNVANFVETETTYWSPIGIIFSYVQVRGSVPVFWEQAADLVPGRQKITIARSPEGTQPAFDKHFDELEHQYGAVHVVNLLSDTKSGELELTTLYRYGIKNCPLSRTTGGQQTSNHALLQCTEYDFHAETKAMGYEAAKDIRSLIEHWADGFAYYLAEEADDAADGGVVASGSRRMVPVLGQEGTFRTNCLDCLDRTNLIQTIISQMAVEAFLGHRGEYATADFWMRHSSLWADNGDSLSKIYAGTGALKTSFTRHGKMSLSGAMADLRKSAQRLYHNNFTDPSRQVTIDMLLGRHVAQKPVHLYDPISDFVSVELSKRSAEFSITKNITIWIGTFNLNGRTDGLDHDLSPWLCPPELRGKQPEIVVCGFQEIVELSPQQIMNSDPSRKQLWEKAVKQCLNSHAQKIGGEKYVLLRSGQLVGAALCIFVKASELENIKDVEGSTKKTGLSGMAGNKGAVAIRFSYANTQICFVTAHLAAGFANYEERNRDYQTINSGIRFQRGRAIDDHDTVIWLGDFNYRIGLDLQNTKELIRQGDLPTLYDNDQLNLQMIAGLAFPFYGEARIAFDPTYKFDVDSDEYDSSEKSRIPAWTDRILRKGTNLKQLSYNCAPLRFSDHRPVYGHFECIVNQIDVARRQKISEELYCKRKEDVGSSTALIDLDDGDTEDEEFIGYESVEPGLPPASSDRQRWWLENGQPARVQIPVPKTRPGQGNGGGHGNGSSNNIKAASGLSQLPGMALNPQRASNPFSNSEEPDWIAVPRSTSQQSVASSISSSPYEVVNIPAMMTATRRPNQTNVPAKFSRLSISEGVPSEATPTATSTRQDPPPPPPPRRQPSTASSTLSTSMSPPTLIHFNTLKPNTGTLPPSMTPRSTPRPVPTSAHSQPQSTLAMAPLKPMTTNPSTSSSSRATPPPVARKPVHLSASPSSIKEDNPSFIEPPPPLPNRASTLPKQQQPGAHADHKATTYATFPGHPSPAMLVVEPKKPATSRNNGVRLPGMTPPVSEQDNKSSLSTQIQAQSPAIASSPSVSPASLPGSKSASSTPTPTNTKPPPPPLPTKRKPLPPLGGLGQSQNQSQAQIQSHVDLLDDQAAVLGGWESLKPEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7M7</accession>
    <name>A0ABR3Z7M7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Multicopy suppressor of a budding defect</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MSB2</name>
        <name evidence="4" type="ORF">Cpir12675_002683</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000055">
        <property type="protein sequence ID" value="KAL1896661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039295">
        <property type="entry name" value="MSB2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35778">
        <property type="entry name" value="SIGNALING MUCIN HKR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35778:SF1">
        <property type="entry name" value="SIGNALING MUCIN HKR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046145820" evidence="3">
        <location>
            <begin position="22"/>
            <end position="1377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1268"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="463"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="648"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="861"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1221"/>
            <end position="1265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1339"/>
            <end position="1377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="441"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="463"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="556"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="868"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="905"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="941"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="978"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1024"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1232"/>
            <end position="1249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1377" mass="141462" checksum="B0BF7B6004521D08" modified="2025-10-08" version="1">MQVKAIVLGTALAMASTAASAELRPRFYFPRQVKREFTNSDSRQGEVFARTNSEESQNNEELPVFTYSTKNEEEETTFEKSVVHIAQAQEPNDELGVSEGYVAAYNNPTAYSSSSSDLPTESSKETSESSTAAPTDLASETTSYQDLKTTPMDIEPEITSYLTVTAPTTVVVPTKPTKIAEDTSSDYPNTYVSQPSSIKSSATEPFVPLPVTTIDDETSRSTNPETYIHVPTSFLIGTGASSYAKSSISSSEPYPTTPGTALESSSNPKSSEPFVTLSTSTNAASSGFPESYVTFPTTSLEDSTPTSTTIASESQITLPATYVDDDSTSTFPETLITIPTTVIDGSISSHLPETYVTVSSSEHSSTEGDRVTTSTRTSSEYEPTSAPAAGSSDREPTLVLGTGHTTSRPASATESYHQPELTASSVEPSSTKPIIIPGPGASTTSSSEQSTIANSLLIPLPESTSGHVGTGTAYTSEDATATTDPLLIPIPESTSGYVGTGTAPVTAPDVETSSNGPVATSTDVPKVGYTSTPGVETNSALESSTSTGPIIVPLPETTTKPVVPLPQSTTSDYAVPAPETTSRGVATTTETPLVPLPVLTTSNLPVDIPQVTTSQPTVDLPKTTSEPLIPLPEVTNVKSLLPLPETTTEPLVPVPQSTTGDYGVPVPKPTTASIVTTEIPELPLPKTTSSEPLVPLPDITSVKSLLPLPETTTEPAVTVPETTGVPYVTTSDPLILLPVLTSSKPQTVPADKTTAPVEYPTSGIPSATASAIETFPTEDAPIPTSTIANESSGIVLGPSGIISSVLDVIPTSNVPLVPGTTADETYVNTATSGAATGITTPMAVPTESATTSDLLRLPLTDSLSEGYTPGAPTAPGSSTTTSGSLVIAPESTTSNLPPTDAPIPTGTQDQTTTGGATDVPAGSSVIGSSAGVPTTGAESLITVNPANPTSTGPTTPGVESTLTPDAPVVGGSEGTGRPTSAPASGAPAATGTDTTAPPSAAPTYGDSIPIDVSSSSSYADGHTADVPAAPTTTQPPVTSIAVVSYIHNTQDWLGTQLVQDTAAPTIASDAPAPTAYEALPSDIPSSIDSGIEITQPDKSTLVRLCFDRNLHYEFVAKNYTAAQQIFANVPRIVSYAEDIALEDVKVTSLVPLQTMNTLGFITTCAHMYVPSDIVTKLSNDINLAISKIYSNPILIAAQLAKTINPSIDIIPGADEALVGNTYAPTNGPKSGSKGGTGNTGKTGGNGGLFGSKSNDDDDSKSPKQKSTAVGITVGAALFVAAGYGAAMFIVARRYKSKKQSHRRSSSISNTSSDMQQAEAGIAPPMMGGALMSREFSSYGAMTPGERESHGSGRSAGPSVRAAGISPPVAAENSLGWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z7Q1</accession>
    <name>A0ABR3Z7Q1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phenol 2-monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_002715</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PheA/TfdB FAD monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000055">
        <property type="protein sequence ID" value="KAL1896693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02979">
        <property type="entry name" value="PHOX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012941">
        <property type="entry name" value="Phe_hydrox_C_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038220">
        <property type="entry name" value="PHOX_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF7">
        <property type="entry name" value="P-HYDROXYBENZOATE-M-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07976">
        <property type="entry name" value="Phe_hydrox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="5"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Phenol hydroxylase-like C-terminal dimerisation" evidence="6">
        <location>
            <begin position="436"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="659" mass="72971" checksum="60186DAA7C6A3A53" modified="2025-10-08" version="1">MPTHYDIVIVGAGPVGLMLSSCLSRWGYRIKHIDNRAEPTETGRADGIQPRSLDLLRNMGLKSAIMAHKPARVYEVAFWDPVGPCAHSNNSDDTKHKRGIARTGTWASCPDFIDARYPFTTLLHQGYIERVFLGDMAKNGTTVQRPWTIGDFNTSNTSKAGYPVEVKLRHVDGADKGEETVQAKYLFSGEGARSSIREKLGIKIRHIDPISYVWGVMDGVVKTDFPDIKPIINSILQMKCTIHSEHGSIMVIPREDDMVRLYIQIASSTDPDFNPRKSTSARQVQASAQKIFQPYSIEWERLEWYSVYPIGQGISDKYTLDNRVFLGGDACHTHSPKAGQGMNTAFLDALNLAWKLHHVESGFASRTILDTYESERRGIAETLLNFDNRYARLFSQKPSAATIEAATEGQDATLGTADKFVQTFKEACEFTSGYGVAYHGNIFNWSPSHPVQSPLIIASSPSSRLCPGRLFPNATVTRVIDANVVHLEQEVPLNGAFRVFIFAGDASNAANRNALFDFGRALEAQTSFLSLYRHSSNVNVSYREMDTPHSRFFTFCTIFATKRAQISVTSDVPEILARYRSHVYADDRNGNSNARGGLTAHEKMGLTNSEGGVIVVRPDGYVGVFVKLVEGTGTVNVLNEYFGAFCTKVPATKALTSHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z825</accession>
    <name>A0ABR3Z825_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">J domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">JID1</name>
        <name evidence="2" type="ORF">Cpir12675_002881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000061">
        <property type="protein sequence ID" value="KAL1896235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="1">
        <location>
            <begin position="42"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="265" mass="29611" checksum="143B1B947CB8CEC0" modified="2025-10-08" version="1">MSPTRAAQSTVYQYIRCLSTSGPSFHNSSSDAPVWPIKPDPSPYEIFNLSPDSAYDKRPFAALVKLYHPDRRHHTESTIDGPTQLDRYRLVVLANELLSNPAKRRAYDTYGLGWVTPGAAHSGGSAAPTNAHEAARQADRRWHSNNGNSAWRNATWEDWEAWHEQQAGSTSAGGMKQEPAYMSNGAFATLVVVLIGTAATMHYSHMESQSASLLNSRQKENQRIMTMLASRERAAADMSREERLLSFIESAGYEMKFEEKDNCMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8A1</accession>
    <name>A0ABR3Z8A1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">GDP-mannose transporter</fullName>
            <shortName evidence="12">GMT</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">VRG4</name>
        <name evidence="14" type="ORF">Cpir12675_002804</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 12">Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 12">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 12">Cytoplasmic vesicle membrane</location>
            <topology evidence="2 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Golgi apparatus membrane</location>
            <topology evidence="12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Endoplasmic reticulum membrane</location>
            <topology evidence="12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the TPT transporter family. SLC35D subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000058">
        <property type="protein sequence ID" value="KAL1896467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00803">
        <property type="entry name" value="nst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08449">
        <property type="entry name" value="UAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="241"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="278"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1896467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="383" mass="41795" checksum="795F9B8E9E7969E8" modified="2025-10-08" version="1">MSDKKNEDYEMRSPGYGERDGFISGRSSALQSNGTDFARISNSPGISIVAYCFASISMTVVNKYVVSGNSWNLNLFYLAVQSIVCSGTIYSLKEAGIIKDLAPYDQSKAKRWFPISMLLVGMIYTGIKALQFLSVPVYTIFKNLTIIVIAYGEVLWFGGNVTPLALLSFGLMVLSSIVAAWADIQHAISGEAVDTSAVDAMATLNSGYAWMTMNVFCTAMYVLAMKKVIKTMNFKDWDTMFYNNFLTIPVLVVMSILVEDWSSENLAKNFPIESRNRLMIGMVYSGLCAILISYCSAWCIRVTSSTTYSMVGALNKLPIAIAGLVFFAAPITFGSVTAIILGFIAGLVYAWARVRQSSASKMTLPTSRATMSASSQSARDANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8B4</accession>
    <name>A0ABR3Z8B4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">HTS1</name>
        <name evidence="11" type="ORF">Cpir12675_002626</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>tRNA(His) + L-histidine + ATP = L-histidyl-tRNA(His) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17313"/>
            <dbReference type="Rhea" id="RHEA-COMP:9665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9689"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78527"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.21" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000053">
        <property type="protein sequence ID" value="KAL1896905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004821">
        <property type="term" value="F:histidine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00773">
        <property type="entry name" value="HisRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00859">
        <property type="entry name" value="HisRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004516">
        <property type="entry name" value="HisRS/HisZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033656">
        <property type="entry name" value="HisRS_anticodon"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11476:SF7">
        <property type="entry name" value="HISTIDINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11476">
        <property type="entry name" value="HISTIDYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001549">
        <property type="entry name" value="His-tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="10">
        <location>
            <begin position="14"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="298"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="298"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1896905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="557" mass="61711" checksum="C98DB37E06F77958" modified="2025-10-08" version="1">MGAKQKFELKTPKGTRDWFGTDITIRDHIFQTITSVFKKHGGVTLDQPVFELKEILTGKYGEDSKLIYDLKDQGGELCSLRYDLTVPFARFLAMNKDIQNIKRYNLSKVYRRDQPAVTKGRMREFYQCDFDIAGTYDPMLPDSEIIRIITEVFNGLGWTGNYTIKLNHRKILDGIFEVCGVPTEKIRTISSAVDKLDKAPWADVRKEMVEEKGLAEEVADKIGEWVVLKGKQDLLQKLRDTPELAANASMKAGMDDLELLFMYLDAFKCLEPVSFDLSLARGLDYYTGLIFEVVTKESRPEEPTAREAPARDETKKSKKPKKPLSEDDDRSSDPSVGVGSVAAGGRYDELVGMFSPKSKIPCVGISFGIDRIFSITKARLAAENREVRKTEVDVFVMALGSGLIKERMQVLATLWDAGINAETLWKTKPRLPNQFKAAEGNGVPFACILGEDEMAKGQVKVKEMGLRDGHPEKEGVLVSLANLAQEVKARIQRKKDLDDITRQAEGLRVVHGIKGAAPLAATDAAAPVEDEAAVSDGAVAAMEEQAPVAAVEPGNKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8B6</accession>
    <name>A0ABR3Z8B6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ketoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_002836</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000059">
        <property type="protein sequence ID" value="KAL1896432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48107">
        <property type="entry name" value="NADPH-DEPENDENT ALDEHYDE REDUCTASE-LIKE PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48107:SF7">
        <property type="entry name" value="RE15974P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="5">
        <location>
            <begin position="8"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1896432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="280" mass="28842" checksum="7E851B5DA804FA8A" modified="2025-10-08" version="1">MSRVLAGKLAIITGGSRGIGAVIADNLAAKGANVVLGYTSASSQAGAQAHADLLAQKHSVQAAIVQADIGVPNGPSDLIAAAKSAFSHADGSFQIDILVNNAGVARNDRIENVKVADFTATYAVNVLGPLLLVQAALPYLPHDRSGRIVSLSSVSSASGFVGQSVYGGSKAAIEAMTRTWARELSERCTVNAINPGPVEGPMYESNTEEFKEMIRPFIKAAPLMKARPGVDSEAVLEYAKTAGGRPAYTSEIAGIVGMLCTPDAAWCTGQVVSANGGFII</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8R0</accession>
    <name>A0ABR3Z8R0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CP-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_002728</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000056">
        <property type="protein sequence ID" value="KAL1896632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01857">
        <property type="entry name" value="HSR1_MMR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043358">
        <property type="entry name" value="GNL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45709:SF2">
        <property type="entry name" value="LARGE SUBUNIT GTPASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45709">
        <property type="entry name" value="LARGE SUBUNIT GTPASE 1 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CP-type G" evidence="7">
        <location>
            <begin position="175"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="259"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="648"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="260"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="330"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1896632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="678" mass="76350" checksum="1A2C99F75ED29FB1" modified="2025-10-08" version="1">MPQARSKVNIGLGNSLMKDRFGKGKGTDRRKTSSVTRINHATGEQYLVNDKQEASWVKMRSVTEQGAMDEFLATAELAGTDFTAEKMTSVKIIHTDHKNPYLLSATEERDVLGKHKTFQASLTVPRRPKWDKNTTAEELDRLEKAAFLDWRRGLAEVQENNDLLLTPFERNIEVWRQLWRVIERSDIIVQIVDARNPLLFRSSDLDVYVKDIDPKKENLLLINKADMMTDAQRRAWATYLKEAGIAYRFFSAQLAKEQLDADAEANEEVSTDSNEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEDSEDKTEDKPQEEATQGGKSFDEATTENPTETPAEAPVEDNEPVPDEEDIRILTVHELENILLSYSPKNLDRKLQVGLVGYPNVGKSSTINALIGSKKVSVSSTPGKTKHFQTIHFSERVILCDCPGLVFPNFAFTKGDLVCNGVLPIDQLREYTGPMSLVAKRIPQAFLEAVYGIQIKTRPVEEGGTGTPTASELLIAYAKARGFQTQGLGQPDESRASRYILKDYVNGKLLFCQPPPGPIDPQEFNRELYDDLHLPERRRAALSHQLDTLSIADTDAVSLAYAGRLPVSSKAHKLDKGFFANKRNASHISRPFNYQYSQQAKETGASKQLTGRKARQMAVLEGTVDAKSSKKHFKGNPSGGKGKNRQNYNDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z922</accession>
    <name>A0ABR3Z922_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000064">
        <property type="protein sequence ID" value="KAL1896014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1896014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="456" mass="50354" checksum="8E5A2A7B1EE4375E" modified="2025-10-08" version="1">MSLQQGFRLQASGAPTRTPNFCPSPASSSPALPRLPAGQESLKWMRTIFGARHISKSQLMQKVPCFIKDCERRVVQDGGMYCDSHSCQCQITANRCCPGPKISSAQYCETHTRCHMPNCRFPRLDAENTQRNHFCVHHTCILHNCGRARIPNFPLCNSHLQRCTSTGCTRFAIRGTLCDAHFCTVVGCSEERVFEGWCQQHACCEGIDCHNGRDKKKRPGTHCSNHALTFCNTVNCNRQTDNHKRFCSAHQCSWETCFEARITINTVPSPCCALHTCTSPGCHRIISQHDSQLCKKHVCQQPGCTSACTSGMPSSWSRSHYCNTHTCIIAGCSWKRAAIDKKGCPAHEELFPAPLITSRELVKQRLRDEAGVVAREEVSRMIMQLAKKSHAAVSPVLAAGDSRQQSISPSSTNCSSGIGCSPLIARVANNGTTSEISGLESLHFPFPTSKETRLQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z934</accession>
    <name>A0ABR3Z934_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Glucose-6-phosphate isomerase</fullName>
            <ecNumber evidence="3 10">5.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PGI1</name>
        <name evidence="11" type="ORF">Cpir12675_002487</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11816"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="EC" id="5.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the GPI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.9" evidence="3 10"/>
    <dbReference type="EMBL" id="JAWDJO010000049">
        <property type="protein sequence ID" value="KAL1897166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05015">
        <property type="entry name" value="SIS_PGI_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05016">
        <property type="entry name" value="SIS_PGI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00473">
        <property type="entry name" value="G6P_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023096">
        <property type="entry name" value="G6P_Isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018189">
        <property type="entry name" value="Phosphoglucose_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035476">
        <property type="entry name" value="SIS_PGI_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035482">
        <property type="entry name" value="SIS_PGI_2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001211">
        <property type="entry name" value="PRK00179.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469:SF1">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00342">
        <property type="entry name" value="PGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00662">
        <property type="entry name" value="G6PISOMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SIS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00765">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00174">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="6 10" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 10 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1897166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="551" mass="60359" checksum="6E890C49E261907E" modified="2025-10-08" version="1">MAPASSLPAWSELQTHRDTSGKSFVLKEAFANDTDRFSKLSTTFKSAATNDILFDFSKNLVTEETISLLVKLAEQAGLEKKRDAMFAGEKINFTEERAVYHAALRNVSGREMKVDGVDVMNVPGGVNEVLQHMKVFSEQVRSGEWKGCTGKKLTNIINVGIGGSDLGPVMVTEALKHYSDRNMTMHFVSNIDGTHMAEALADSDPETTLFLIASKTFTTAETTTNANTAKKWFLEKTANKGEIAKHFVALSTNETEVAKFGIDPKNMFGFENWVGGRYSVWSAIGLGVALYIGFDNFYKFLSGAHEMDNHFCNTPLKDNIPALGGLLSVWYSNFYDAQTHLVAPFDQYLHRFPAYLQQLSMESNGKTTTSNGSPAKYTTGPILFGEPCTNAQHSFFQLVHQGTKLIPTDFILAAKSHNPISNNLHQKMLASNYLAQAEALMVGKTAEEVRAEGCPENLVSHKVFPGNRPTTSILVGGTIGPAELGALIAYYEHLTFTEGAIWDINSFDQWGVELGKVLAKKILKELDEPGNGSGHDASTGSLISAFKQFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z969</accession>
    <name>A0ABR3Z969_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Large ribosomal subunit protein mL67</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_002475</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL67 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000048">
        <property type="protein sequence ID" value="KAL1897218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024629">
        <property type="entry name" value="Ribosomal_mL67"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28184:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML67"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28184">
        <property type="entry name" value="MITOCHONDRIAL HOMOLOGOUS RECOMBINATION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12829">
        <property type="entry name" value="Mhr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="217"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="217"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00035185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1897218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="261" mass="29210" checksum="42CC4C17E6980A48" modified="2025-10-08" version="1">MSVFPASRFSVGQLALRTSVRFGHTNPQWKQPRPDLAGHAPGHGEKIYIYTHIGTDEIVYSHTSVLNVYKTFKQMPFAGKKNKPAKIRKDLWRQLAVVSFPSGQGVVGQSVFQRLREFRTRHLHEWGDEMFLKPNPAKPSLKLSRSRKERGAAIIAQKPNSIADLAAVLAGAGAGSRMWIQDESGSKVLCPTTVQWANAGDYQYAQSWTDNVAHMEMDQEQREEPVEVEERAEDDAQDSSPVAPTEELSEPKKKGLLSWVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z976</accession>
    <name>A0ABR3Z976_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Carboxypeptidase</fullName>
            <ecNumber evidence="12">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Cpir12675_002468</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Vacuolar carboxypeptidase involved in degradation of small peptides. Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="12"/>
    <dbReference type="EMBL" id="JAWDJO010000048">
        <property type="protein sequence ID" value="KAL1897211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008442">
        <property type="entry name" value="Propeptide_carboxypepY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF113">
        <property type="entry name" value="SERINE CARBOXYPEPTIDASE CTSA-4.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05388">
        <property type="entry name" value="Carbpep_Y_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 12" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <keyword evidence="8" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="Propeptide carboxypeptidase Y" evidence="13">
        <location>
            <begin position="38"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF05388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1897211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="546" mass="60538" checksum="0E46AF6A63E1943F" modified="2025-10-08" version="1">MKPSYIFGAATAVLASEQVVFHEPNDAPSSLKTENKPGASIWDSLQESISEVGSEAKALWDEISMIAPEAVQAFKSAQAAQVKASKKVNRKPDSAWDYVVKGNHVQNLMAQTDGKNHAKIDGDIGSYSLRAKAVNPKKLGIDSVKQYSGYLDDEENDKHLFYWFFESRGDPKKDPVVLWLNGGPGCSSLTGLFLELGPASVDKKLKVVDNPFSWNNNASVIFLDQPVNVGFSYSKKPVSTTTAASKDVYALLSLFFHQFPEYATQDFHIAGESYAGHYIPAMASEILEHPNRNINLKSVLIGNGLTDGYTQYAYYRPMACGDGGYPRVLSESECQAMDNALPRCQSLINSCYESGSTWSCVPASIYCNNAMIGPYQRTGQNVYDIRGPCEDSSNLCYSGLGYISDYLNQDHVKEALGVEVDGYESCNFDINRDFLFAGDWFTPFHRLVPGVLEEIPVLIYAGDADYICNWLGNQAWTNELEWPGHKAFESAKLKPLTLDGDQYGRVKHSGNLTFMQIYGAGHMVPMDQPANSLDFYNRWLAGEWRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA38</accession>
    <name>A0ABR3ZA38_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uracil permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">fur4</name>
        <name evidence="7" type="ORF">Cpir12675_002600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000052">
        <property type="protein sequence ID" value="KAL1896951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11482">
        <property type="entry name" value="SLC-NCS1sbd_NRT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012681">
        <property type="entry name" value="NCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045225">
        <property type="entry name" value="Uracil/uridine/allantoin_perm"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00800">
        <property type="entry name" value="ncs1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618:SF2">
        <property type="entry name" value="ALLANTOIN PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618">
        <property type="entry name" value="NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="352"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="432"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="481"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="522"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="552"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="601"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="631"/>
            <end position="653"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1896951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="708" mass="78596" checksum="99AE9A1D2545579A" modified="2025-10-08" version="1">MIKAQGTAKLFPPGEDIEDPILARFADCVLSKVRAAMVDDEGLISKISTNPEDDDTVFVGYLPFSTTESLHSCRTIQFSKLQELGRLGLSSRKVCFTESFQQYLVFPFGATFLGCFFPWRASVRVVFTEIPRLIHSSRVVDIMFVNQYPRDEELVQVELAQPRYLTCILAIPLINYDLKPVEQARRAWGPWNFVGFWIADSFNINTWMISSSMIVGGLSWWQSWLCVWIGYAISGGFICMTGRIGATYHIGFPVASRSSFGIWGSLWPVFNRAAMAPPPPACIWYGVQSYIGGHCVYLMIRSIWKSWDRNTIPNTFSESSGTTTADYASFFIFWLCSLPAIWFPVQQIRHLFTVKAFFVPCAGIGFLIWAVVRAGGIGPIIHQPSSLHGSDLAWEFVKGIMSSIANFATLIVNDPDFTRFAAKPKDAFLPQLISIPLGFGITSFIGIIVSSSSTVIYGDSIWDPLDLLERFIDDGGAGERFGVFIIAFAFALAQLGTNIAANSVSAGTDMTALLPRYLTIRRGGYICAAVGLAMCPYTLLTSSNKFTTYLSAYSVFLSSIAGVIVADYYIVRKGFLELRDLYSSSREGPYYYRYGVHWRAYVAYISGILINVVGFAGAVGQDVPAGAEYIYNLNFFAGFIVSAGMYWILCHFFPVPACSSTWMEINNDVENFTAAHAVARGGESYVDEGWNMQPSDEKAAPQMESKMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAX4</accession>
    <name>A0ABR3ZAX4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cholesterol esterase</fullName>
            <ecNumber evidence="3">3.1.1.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TGL1</name>
        <name evidence="3" type="ORF">Cpir12675_002386</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.13" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000046">
        <property type="protein sequence ID" value="KAL1897282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004771">
        <property type="term" value="F:sterol ester esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006693">
        <property type="entry name" value="AB_hydrolase_lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11005">
        <property type="entry name" value="LYSOSOMAL ACID LIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04083">
        <property type="entry name" value="Abhydro_lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="Partial AB-hydrolase lipase" evidence="2">
        <location>
            <begin position="106"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="524" mass="58445" checksum="9AC33FBDE8D5E285" modified="2025-10-08" version="1">MPFVGRLNPAEYLALMLSFALVGFEALIRVMTLALPTSLLSFFYSASRRLFLCYASRPLLAPATESDCTLSADGDDVISDFPRHDSSHCDASPLAPSAVRDASDFVDLCQLHGYAAEEHVVQTKDGYLLGLHRLAWKKGEEGQRVNDGIDSIHKRVVYLHHGLLMNSEVWVCQTEARRSLPFQLVERGFDVWLGNNRGNKYSKKAVNRSPTDAAFWNFSIDEFAFHDIPDSIAYVLSTTNQSSLSYIGFSQGTAQAFAALSIHPQLNNQVNVFIALAPAMSPAGLSNGIVDALVKASPQVLFLLFGRGSILGSATLWQSILYPPIFVRIVDRGMRFLFNWETRNISESQKLAAYPHLYSYTSTKSVVHWFQIIRNKTFQMYDDDVAAMHVPLAGLQGSASKYTRVARYPTRNIKTPIALVYGGSDSLVDIRVMLRELPDSTVATEVPHYEHLDFLWATDVDQKVFTHVFDALDKFTCPVLDQSLFGQNRHAQQRDLSLVNELRSQSKIVTAVNGSKHLVNGSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB72</accession>
    <name>A0ABR3ZB72_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002337</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000045">
        <property type="protein sequence ID" value="KAL1897482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="175" mass="19560" checksum="C324024254FCCA75" modified="2025-10-08" version="1">MAREDLHDLEELGYILGPREPEEALLGEEEEEEEEEEGEEDKDTSDKRNKEKTKQQPPQKHAVGSKASTASRTSSAKKNSSPSKKQVREQLVSTRLPWFESFIGDLASGGHLRHHHGKHTSRDGNTHVEWEVVELTGDGFEKEEEEDEGGQKEGDSKMVGTQGKRKLEVLEGGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBI2</accession>
    <name>A0ABR3ZBI2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Xanthine/uracil permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_002514</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000049">
        <property type="protein sequence ID" value="KAL1897193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045018">
        <property type="entry name" value="Azg-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43337">
        <property type="entry name" value="XANTHINE/URACIL PERMEASE C887.17-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43337:SF1">
        <property type="entry name" value="XANTHINE_URACIL PERMEASE C887.17-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="211"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="383"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="512"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1897193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="540" mass="58201" checksum="6BD32557C81B5549" modified="2025-10-08" version="1" fragment="single">PRERKGSYFLTEMRAGLATFFAMAYIIAVNSSIVADSGGTCVCDVDDCVTAPSDAYMLCISEIKRDMVTATAAISALGTFFIGLLANMPVGIAPGMGLNAYFAYTVVGFHGSGKVPYQVALTAIFIEGWIFLGLTMLGMRQWLARAIPRSIKLATSVGIGLFLTLIGLTYSEGLGIVVGATSTPTELAGCLQEDMVDGLCPTSKKMRSPKMWIGIFCGGILSTMLLLYRVKGAIIFGIILVSIISWPRNTEVTNFPYTAVGNDNFDFFKKVVDFHKIKHTLNVLEWDISGYGNQFGLAIITFLYVDILDCTGTLYSMARFASLIDPVTQDFEGSSMAYTVDSITISIGALFGTPPVTAFVESGAGISEGGKTGLTSMCTGICFFISIFFAPIFASIPTWATGSVLVLVGSMMAKEVVAINWEYIGDAVPAFLCLAIMPFTYSIAYGLIAGVCSYICINTLVWLIELASGGRIVPPNKNMKEPWTWRIPGGILPPWFNRLIHGKKDFWRPESPAVTEGAIDGGAAKTSDSLGPEKQQPYEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBS1</accession>
    <name>A0ABR3ZBS1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutaredoxin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002069</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000036">
        <property type="protein sequence ID" value="KAL1898120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008554">
        <property type="entry name" value="Glutaredoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052565">
        <property type="entry name" value="Glutaredoxin-like_YDR286C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33558">
        <property type="entry name" value="GLUTAREDOXIN-LIKE PROTEIN C5ORF63 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33558:SF1">
        <property type="entry name" value="GLUTAREDOXIN-LIKE PROTEIN C5ORF63 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05768">
        <property type="entry name" value="Glrx-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0249">Electron transport</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="116" mass="12902" checksum="10E48F66D0F42900" modified="2025-10-08" version="1">MFASSILRQCRITLFTRATCGLCDYAKAVLTQVQEKRAFELQHVDLSAATGEKETGGEKTEMQMWKDLYDFDVPVIHVAKASAPPESPSRAAKAVKLMHRMTPADVEAKMDAVEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZCM6</accession>
    <name>A0ABR3ZCM6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">DNA replication ATP-dependent helicase/nuclease</fullName>
            <ecNumber evidence="19">3.1.-.-</ecNumber>
            <ecNumber evidence="19">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="primary">dna2_2</name>
        <name evidence="23" type="ORF">Cpir12675_002221</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="25">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="19">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="19">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 19">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="19"/>
    <dbReference type="EC" id="3.6.4.12" evidence="19"/>
    <dbReference type="EMBL" id="JAWDJO010000040">
        <property type="protein sequence ID" value="KAL1897795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18041">
        <property type="entry name" value="DEXXQc_DNA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22318">
        <property type="entry name" value="DNA2_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026851">
        <property type="entry name" value="Dna2/JHS1_DEXXQ-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014808">
        <property type="entry name" value="DNA_replication_fac_Dna2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF433">
        <property type="entry name" value="DNA REPLICATION ATP-DEPENDENT HELICASE_NUCLEASE DNA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08696">
        <property type="entry name" value="Dna2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 19" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="11 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="19" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 19" id="KW-0227">DNA damage</keyword>
    <keyword evidence="15 19" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 19" id="KW-0235">DNA replication</keyword>
    <keyword evidence="14 19" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="23" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="10 19" id="KW-0347">Helicase</keyword>
    <keyword evidence="9 19 23" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 19" id="KW-0408">Iron</keyword>
    <keyword evidence="13 19" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6 19" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17 19" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5 19" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16 19" id="KW-0539">Nucleus</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication factor Dna2 N-terminal" evidence="20">
        <location>
            <begin position="25"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="21">
        <location>
            <begin position="595"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="21">
        <location>
            <begin position="695"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="22">
        <location>
            <begin position="771"/>
            <end position="1003"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU367041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF08696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAL1897795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1158" mass="129417" checksum="9DB26B617443DB5A" modified="2025-10-08" version="1">MKIVGVEEGEHEMQMQKIVTLQPEDSNPTVTVFLRDLWAEPDLEIGPWAYVTGSFSADGACIVDMDQNYFILEPDHLVSITTLADAFSCVRKAVLQDRVRATGAPSKPLVYGTILHEIFQAALFKMDFSPAFLGKVIAETLDEHVEDLFSIKLDPRAACEEIQGKMAAMRTWAERFISPVPKASAKVSGIHGKNPATMCISKLLDVEEHVWSPMYGLKGNIDATVQVTIDDKNGTRTLTVPFEVKTGKNESISHRAQTTMYTMLLSDRYDIEILTGILYYTETGNTKIIPAIRNELVHMIMKRNELSESLRRRTLPPMATSKNTCRGCFAKTECSIFHRLSEGGTAETSNFPDEFNKIAGKLTATHQEFFRKWDDLLTYEEKHGEHAKREIWAMTSIERQAVNRGVSDCVIKDMHESSERSFAKFSYTFVRHNPRSGPAFTESAFNIYDPVVISDEEGHFALAIGFVEDIRKDAIRLKVDRRLHNQRIRQAGFDAVNNQVFAGINEVVPEGVQMHDLKQDREHIQSQSQHHHPVRYRLDKDEFGNGMARVRHNLVAIMDDLLYGSIKIRELIVDLKPPTFRAEPTQYHVANMDALNIDQRAAIEKVMSAQDYALVLGMPGTGKTTTIAHIIRALVAQKKTVLLTSYTHSAVDNILMKLKDDNIPVFRIGSKSKVHSRVAEFASLDCDKQSDFAAIERVWLHSPIVATTCLGIGHAVFSERIFDYCIVDEASQITLPVCLGPIRMARTFVLVGDHYQLPPVVQNEQARAGGLDVSLFKLLSDNHPASVVNLEHQYRMCEDIMTLSNELIYKGQLKCGTRALKTLKLQIDGMEALEEHHYNHSSPTTVSDTTSAYLTACPGLSDSTCWLRHVVDPENRAIFLNTDALGPGSCESRLGNRIINEGEVCIVVQIVEALLSVGVREDDIGVMTHYRSQLSLLGKGLGHRTAIEMYTADRFQGRDKEVVVLSLVRSNDQHNIGELLRDWRRINVAITRSKTKLVVIGSKATIIGAGADEMIHQFVRLMDTRGWTYDLPPAALTDHAFTAAATQFDASMFSPRRTSPSQRKTVLVCKQQKNQNLLKALQADRPSRDPRNHSVLEFFGKENSPVTNGNVSAQSAPVFGAEIGPKKIVGLNGKARMKSCPVTRDILNEFSNGAFSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZD74</accession>
    <name>A0ABR3ZD74_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cytochrome c oxidase assembly protein cox15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">COX15</name>
        <name evidence="14" type="ORF">Cpir12675_002188</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>Fe(II)-heme o + 2 A + H2O = Fe(II)-heme a + 2 AH2</text>
            <dbReference type="Rhea" id="RHEA:63388"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:60530"/>
            <dbReference type="ChEBI" id="CHEBI:61715"/>
            <dbReference type="EC" id="1.17.99.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:63389"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Porphyrin-containing compound metabolism; heme A biosynthesis; heme A from heme O: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000040">
        <property type="protein sequence ID" value="KAL1897763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01665">
        <property type="entry name" value="HemeA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003780">
        <property type="entry name" value="COX15/CtaA_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023754">
        <property type="entry name" value="HemeA_Synthase_type2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23289">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23289:SF2">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02628">
        <property type="entry name" value="COX15-CtaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="280"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="340"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="406"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="446"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="471"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1897763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="514" mass="55638" checksum="8E9FDFE72992EA3B" modified="2025-10-08" version="1">MAFLMPGARRLPMALKLAPGPAPVLAAATRQCLPLPLNLAPRPSVYMAAMSVKQSNFQSLAAVKMQMRMFSNASHKLGAPAAAAPKIKMQVASAFTSSPSSSPSSPSSSSSSPSPSSFPEKTTSKAVAVWLIASAVSVFGIVVWGGLTRLTESGLSITEWRPVTGSMPPRNGEDWESEFTKYKASPEYAILNPKMTLDEFKKIYFMEWSHRLWGRTVGITFVLPALYFIARRRVSRRMATNLLGISTLIGFQGFIGWWMVKSGLKDDLFAPGSHPRVSQYRLAAHLGTAFVCYSWMLLSAVTVLRTRRLLADPTAGLKLARALAAPAVTRFRTITTAISALIFATAMSGALVAGLDAGLIYNEFPMMGLGLTPSAAELWDSFYSRRADGSDLWWRNILENPSLVQLNHRILAMTTFSCVLALFAYSRRGPLAAALPPNVKKGTLGLVHLVCLQAALGISTLIYMVPTHLAATHQAGALALLTGALVLCHRLRIPKSTVRMLEQKIAAASKPMSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDE7</accession>
    <name>A0ABR3ZDE7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NRAMP-like transporter smf-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SMF3</name>
        <name evidence="7" type="ORF">Cpir12675_002055</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000036">
        <property type="protein sequence ID" value="KAL1898106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001046">
        <property type="entry name" value="NRAMP_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01197">
        <property type="entry name" value="nramp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF037982">
        <property type="entry name" value="Nramp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11706:SF101">
        <property type="entry name" value="MANGANESE TRANSPORTER SMF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11706">
        <property type="entry name" value="SOLUTE CARRIER PROTEIN FAMILY 11 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01566">
        <property type="entry name" value="Nramp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00447">
        <property type="entry name" value="NATRESASSCMP"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="275"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="427"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="471"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="518"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="548"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="605"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="79"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="16"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="630" mass="66140" checksum="776C236EDD2FAA3A" modified="2025-10-08" version="1">MNRPSRTDEPYEGEGYNQSPNVLSNDLTTNADLGGIANARHLRGDASSGPGPAGGSSAAEAVSQFPGCLDSIVGPPGSLSAGLADEGEGGFGGGKDAAEGTVRGGHVGVTVRRRLGEEEEGDEAFPRASTTTIGESSVRLVANGGDMNGPSTRMQKVKAMAFKYASFIGPGFMISVAYIDPGNYATDVAAGASYRFKLLFIVLLSNIIAIFLQTLCIKLGTVTGLNLASACRAFLPLWLNYVLYVFAECAIIATDIAEVIGFAIGLNLLAPKVPLVAGCAISILDVMVTLMFYQPHGTIRGLRFFEMFIVSLVLGVVVCFCIQLSLIENTSVGDVFRGYLPSSALVESKGLYQACGILGATVMPHSLYLGSGIVQPRLRDYDERHGLLPKQLQARNIIDGSNNTDEASYIPSLQAVRHSLTTSSLELGLSLFTFALFVNSAILIVAGASLYNNPAAPDADIFSIHQLLSESVSSGAGTLFALALLLSGISAGIVCTIAGQMVSEGALNWRCAPWLRRLITRGISVTPSIVIAAAVGRDGLSSALNASQVALSIILPFVAAPLVYFTCCNKFMMVVPGARVRVRGDESGVRADGCVSMANEWYTAALASIIWVFIAVLNVANIVLMVKGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDL3</accession>
    <name>A0ABR3ZDL3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Signal peptidase subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_001912</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Essential component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Essential for the SPC catalytic activity, possibly by stabilizing and positioning the active center of the complex close to the lumenal surface. Essential for viability.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SPCS3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000033">
        <property type="protein sequence ID" value="KAL1898367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007653">
        <property type="entry name" value="SPC3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12804">
        <property type="entry name" value="MICROSOMAL SIGNAL PEPTIDASE 23 KD SUBUNIT SPC22/23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12804:SF0">
        <property type="entry name" value="SIGNAL PEPTIDASE COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04573">
        <property type="entry name" value="SPC22"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016089">
        <property type="entry name" value="SPC22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00045670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR016089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1898367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="224" mass="25116" checksum="8C736C34E0CA4459" modified="2025-10-08" version="1">MYNIVTRFQSAFGFFTTVLFTVATLVALSDICVPREPTASIAPKDLKVISGRAHYHSTKKTDLASIRFSLDADFSSLFTWNTKQVFVYVTAEWDTPATKNTPAGHSSAVIWDQIITAPSSDFLANFGPATMKKLRRSAAGKTIDPSRGKLHIENQRPKYQITHPSGTLAKTPDVRLKVHYNVQPWVGLLTWDMYRNILIWKRIDKGESKSFNLPAIKAKPSQKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZE85</accession>
    <name>A0ABR3ZE85_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glutaminase</fullName>
            <ecNumber evidence="2">3.5.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SNO1</name>
        <name evidence="7" type="ORF">Cpir12675_001823</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-glutamine + H2O = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaminase PdxT/SNO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.2" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000030">
        <property type="protein sequence ID" value="KAL1898715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036381">
        <property type="term" value="F:pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01749">
        <property type="entry name" value="GATase1_PB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01615">
        <property type="entry name" value="PdxT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002161">
        <property type="entry name" value="PdxT/SNO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021196">
        <property type="entry name" value="PdxT/SNO_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03800">
        <property type="entry name" value="PLP_synth_Pdx2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31559">
        <property type="entry name" value="PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31559:SF0">
        <property type="entry name" value="PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01174">
        <property type="entry name" value="SNO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005639">
        <property type="entry name" value="Glut_amidoT_SNO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01236">
        <property type="entry name" value="PDXT_SNO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51130">
        <property type="entry name" value="PDXT_SNO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1898715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="247" mass="26419" checksum="1466C86854A0475C" modified="2025-10-08" version="1">MVSSVTVGVLALQGGFHEHLNLLRQASKAISSQTVTLDFIEVRTPAALGRCDALIIPGGESTTIANIAEQSGLMQPLRDFVKKPVWGTCAGLILLSDEASATKQGGQTLIGGLNVRVQRNHFGRQIESFFTPLDLPFLSSSTEGVANEPFQAVFIRAPIVEEILPPKPPQNTPAQVLVSLPGREDSKGGDSKTAASHGDIVAIQQGNILGTSFHPELTNDSRIHEWWLRQVLDAAAQTTVGQQDIQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZES5</accession>
    <name>A0ABR3ZES5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_002126</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000038">
        <property type="protein sequence ID" value="KAL1898039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17330">
        <property type="entry name" value="MFS_SLC46_TetA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF8">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G03730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="293"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="374"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="402"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="439"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="468"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="20"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="499"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="503"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="533"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="553"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1898039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="575" mass="62298" checksum="499686D59F70B792" modified="2025-10-08" version="1">MAPPSSPGPGPKKAKLPVHQLAILSIARFCEPVALMSIFPYLPEMIQSFGIPKHEVAKWAGIITGTFAVSQSLTAVAWGQASDRWGRKPTILMGLVFSLLCFLVWGFATDLKTAIVIRFIQGASNGNVGIIRTMVAEMVTEKELQPRAFSIMPLVWSIGSIFGPAFGGFFAKPAQRFPDFFGHSKLLQNYPFALPNLIAAAFFLISITTGVLFLKETLDHKRHQDDWGILIGKRLTNSLRLRGSNGAFRRASFVDGEATAPLIPSRVLTKPHRRSPPKAGIAECFTRQSTIALIAYMGLAVHSMAYDQIIPVFLNMAVDDHTGPETQLPFKFIGGFGWESDKIGTVFTIYGLMCSLVQFIIFPPLCNYIGVRNCFRTCVFVMPLAYFLTPFTVLISDPTIRTGALLAVMSLKAFGIILAFPCVIILLTNSASSVRILGTLNGVATTVSAIGRAVGPAVTGWIFSRGVVAGYIIAPWWFLTLISIAVIIPSWMLEDGEGPSALADEENDNSSVDDSENAIEDDDDCETIYAEPTSKTPLLANGSSERVDYKTNASSSSSASSLAPAPLSQGQRQAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEX3</accession>
    <name>A0ABR3ZEX3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 12">Chitin synthase</fullName>
            <ecNumber evidence="2 12">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">CHS3_2</name>
        <name evidence="15" type="ORF">Cpir12675_001767</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine = [(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9595"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="EC" id="2.4.1.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:16638"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Cell membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the chitin synthase family. Class III subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2 12"/>
    <dbReference type="EMBL" id="JAWDJO010000030">
        <property type="protein sequence ID" value="KAL1898661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04190">
        <property type="entry name" value="Chitin_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013616">
        <property type="entry name" value="Chitin_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF11">
        <property type="entry name" value="CHITIN SYNTHASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01644">
        <property type="entry name" value="Chitin_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08407">
        <property type="entry name" value="Chitin_synth_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 12" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4 12 15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="577"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="640"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="669"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="711"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="756"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="849"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="889"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin synthase N-terminal" evidence="14">
        <location>
            <begin position="152"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="104"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU366040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1898661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="924" mass="104021" checksum="9CCB23CB8E62835E" modified="2025-10-08" version="1">MAYHGQGNNDYEGEPLRDLPPAGRYHIPPADDSEESNHSLLRDNHTPSNDYGQMNQSGHLGESLAVQPPDRPMSAYSLTESYAPGAQLNQGPAAPPSPGYHNDPYSTQQYSSDFDNTGGYGGYGDRPVSTADPDDNWVARQQVSGGLKRYATRKVKLVKGTLSLGYPVPSAIKNAIQPKYRDVEGGNEEFMTMRYTAATCDPNDFTLKNGYDLRPRMYNRHTELLIAITYYNEDKVLLSRTLHGVMQNIRDIVNLKKSTFWNKGGPAWQKIVVCLVFDGIEKTDKNVLDVLATIGVYQDGVVKKDVDGKPTLAHIFEYTSQLSVTPNQQLIRPMEDSPQTLPPVQFIFCLKQKNSKKINSHRWLFNAFGRILNPEVCILLDAGTKPSPKSLLALWEGFYNDKDLGGACGEIHAMLGRGGRKLFNPLVAVQNFEYKISNILDKPLESSFGYVSVLPGAFSAYRFRAIMGRPLEQYFHGDHTLSAQLGKKGIDGMNIFKKNMFLAEDRILCFELVAKAGQKWHLSYIKGAKGETDVPEGAPEFISQRRRWLNGSFAASLYSVMHFGRMYKSGHNLVRMFFLHVQLLYNILTVVFSWFSLASYYLTTTVIMDLVGTPVPQTPSTNKYHAWPFGDSASPIINDVLKYIYLAFVILQFILALGNRPKGSKWTYISSFLVFALIQGYTIVLTFYLVVRGLRDVDIDTDLKMGSGSDFVSTFFTGSSAAGVIIVSLVCIYGLYYIASFLYLDPWHMFHSFPAYMLLTSTYINILMVYAFNNWHDVSWGTKGSDKAEALPSAVVQKGEKNEVVVEEIDKPQEDIDKLFEQTVKRALEPYKEADDMERKDVEDGYKSFRTGLVVSWLFSNISLIVIITTDNFNSFGMNQTSTERTANYFKFLLYATAVLSLVRFMGFLWFLGKTGLMFCMSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZFE2</accession>
    <name>A0ABR3ZFE2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">CCA tRNA nucleotidyltransferase, mitochondrial</fullName>
            <ecNumber evidence="8">2.7.7.72</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CCA1</name>
        <name evidence="8" type="ORF">Cpir12675_001677</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.72" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000027">
        <property type="protein sequence ID" value="KAL1899017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004810">
        <property type="term" value="F:CCA tRNA nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05398">
        <property type="entry name" value="NT_ClassII-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3090.10">
        <property type="entry name" value="cca-adding enzyme, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032828">
        <property type="entry name" value="PolyA_RNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13734:SF5">
        <property type="entry name" value="CCA TRNA NUCLEOTIDYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13734">
        <property type="entry name" value="TRNA-NUCLEOTIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12627">
        <property type="entry name" value="PolyA_pol_RNAbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81891">
        <property type="entry name" value="Poly A polymerase C-terminal region-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly A polymerase head" evidence="6">
        <location>
            <begin position="41"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding" evidence="7">
        <location>
            <begin position="213"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1899017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="513" mass="58106" checksum="DFBC0FFEDD19EA1B" modified="2025-10-08" version="1">MSTSLLPRINLTSNETRLKDLLLDLTASLAQDQPNGPIVLRWAGGWVRDKLLRIESNDIDVAINCMTGETFGLELGKFCQQAWVVEKYDIKKDDLHGLHLIRLNPEKSKNLETATTQLFGVDLDFVNLRKETYAQDSRNPEVEFGTAYEDAMRRDATVNAMFYNLHSDSIEDHTGGVADLKAKVIRTPLEPFQTFMDDPLRVLRLVRFASRLGFTIAQNTSQCMSDPRVLNALALKITRERVGIELDKMLKGNDPRAALELIYELGLYHTIFTNVTQPDIPEPDIANWPTAFNLLHDMSKNGFGDFPYNTLVTDSNESYLAWALACLCPWENIPTPQSGQKPKSKSLPQIVTVAREGFRATNKLSDCLTGSHKNIDEIRRFKDAVLEGQLWAKKRGAVAMMIRRWEGNAMNWRLQILYAMLVEALQYPSDATQELENLRVTWALVLKELENLNLMDAHLVVGLVDGRTLSKALNKRPGQWMRPALDICLEWQFDNPGDTDITKPIDAAREIYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZGW9</accession>
    <name>A0ABR3ZGW9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tudor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_001338</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000020">
        <property type="protein sequence ID" value="KAL1899660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20446">
        <property type="entry name" value="Tudor_SpSPF30-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041297">
        <property type="entry name" value="Crb2_Tudor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46297:SF2">
        <property type="entry name" value="TUDOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46297">
        <property type="entry name" value="ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18115">
        <property type="entry name" value="Tudor_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00333">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tudor" evidence="4">
        <location>
            <begin position="100"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="173"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="219"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="61"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="220"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="243"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1899660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="310" mass="33825" checksum="4DD0BF8A28A56B5C" modified="2025-10-08" version="1">MSNQSELEQDRLLYQEQLILVESQLKEDSDNGELKGLIEELTQIISFLNESLAELKPKESQPATTQTISTSASPGPKKTDLTTQTIAAVPAANHTDDEITTYRVNDTVLARWASGDRGFYPARITSITGSVTAPVYTVKFKSYDTSETLRARDIKPFSNKRKADDTIISDSAPVSITSGSSTPAVKSPSTFSPIPNAPGASAATGTVVSAAASLYPDQVTRMRAEKGTLDDEDKPRKAKKMKANKELEAGKSKWQDFQTKSKFGKTQKKDSMFRTPEGVNGRVGFTGSGKAMRKDSTRTRHVYQPADDMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH60</accession>
    <name>A0ABR3ZH60_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA-binding protein, CCR4-NOT complex subunit Rcd1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rcd1</name>
        <name evidence="3" type="ORF">Cpir12675_001340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CNOT9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000020">
        <property type="protein sequence ID" value="KAL1899662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007216">
        <property type="entry name" value="CNOT9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12262">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04078">
        <property type="entry name" value="Rcd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="381" mass="43112" checksum="F3616DB8BAF4527B" modified="2025-10-08" version="1">MIPAAHVYQHHQFHAQPESSWMQQQSQQQQQQQQQQQQQQQQQHQQQQQQQQQQQQQQHLVAAAASAAQQQHFNRLANHGPMVGISNTHVHETSHEMVVSEDNRRTMAFIADLLNENTREAALLELSKKREQVQELALILWHSFGVMTSLLQEIISVYTLLSPSQLTAAASNRVCNALALLQCVASHNETRTLFLNAHIPLYLYPFLNTTSKSRPFEYLRLTSLGVIGALVKNDSSEVINFLLTTEIIPLCLRIMETGSELSKTVAIFIVQKILLDDNGLNYICATYERFYAVGTVLSNMVTQLVEQQTARLLKHVVRCFLRLSDNARAREALRQCLPEPLRDATFSAVLRDDAATKRCLAQLLINLTDPSIEHGAGAHNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZH75</accession>
    <name>A0ABR3ZH75_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thiosulfate sulfurtransferase rdl2, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RDL2</name>
        <name evidence="2" type="ORF">Cpir12675_001111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000016">
        <property type="protein sequence ID" value="KAL1900006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01519">
        <property type="entry name" value="RHOD_HSP67B2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44086">
        <property type="entry name" value="THIOSULFATE SULFURTRANSFERASE RDL2, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44086:SF10">
        <property type="entry name" value="THIOSULFATE SULFURTRANSFERASE_RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="89"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="193" mass="21358" checksum="586B4E2D2E995CFE" modified="2025-10-08" version="1">MSSYRIASIITPRAVIRASSTSVPRSFAPSALLTRCLASAQPSTHSFQTGRATAIKIASRRAFSSSTLTTQEKVEVFDYEKMKKLVAEQPEEYIIVDARERGELVQTGTIPNAVNIPIASSPDSFQIHNEDFEDRFGFERPEKDKILLFFCKAGVRSHAAAKLARDAGWKTAEYPGSWVDWVAKGGDITHSFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI35</accession>
    <name>A0ABR3ZI35_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000019">
        <property type="protein sequence ID" value="KAL1899715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185:SF1">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1899715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1115" mass="122606" checksum="0F62BAB82E4625A6" modified="2025-10-08" version="1">MYRDVMTAGYATSPAPATPSGTVAVPRNLLSLDGGGLQSFSSVVFLHELMLEIQKLQDLKTLPSPCRYFHLIGGTGVGGVLALILGQLQLSTQDLLDVCHENWVLPIYRESRFFTHLFKRCQARVNDRRPSASHRIHPPLTNSHVSRASLQGLSLYSHEMQGLAPVPETPEHDGGFVHDTRCFAVARRCDTGSETPILFRSYGAPSSAIGACPVTQMDEYDEDMHGPQHSDSPFSEDYFSQAAKCVVDVAFQFPRRPNRAIRNPDIIDGSSMWCNPSELLLREANDLFGFDGRLGVLVSLGAEPNPSLGWRVDARVVHSQIERRLEEQHLKDDQLGIQMPRQRRYFRLSDGSMLPQTPVELVTHSAILEVLSTAEAWVEDNHAVIEELAQAVTQALSAEDAGGPAFSKIVPGLAVTHLEIEKKPPAAESRKDSLWSHNDASPLPMLPESSLSTTPPLLMASLCSLPSSIGQPLEIGHSSLLNAARENSSDGRSARTATRLLHILSFLAPQNIAPEIIALAASSQAVRQGETAGHISLTGTNFPMALFTQQPIDHIQRQNYLVSSLNISPEACTTAFTALENLGLLTVEQQPAPNWPQPLAWFSISPDMQRHVRLAMGTSQLQESLWAGSTIVHYSLATPSQFPFFLAQRWLPHCYALQRHTAELFKRGTYTEYSDHDSAVQSTVRAQLFAACGFAPFAAAVMPDVLAILYQDYAVNGEQACLDVALQASLLYADILLQANCPVESAYVCEEARQRATEANRCSSLSQLSHKLDLALRAKEICARLLAGDKKSVDVNVDLDISAIRTVAIEDSSYVSSATDVDVGLFLDIAYAYALLRDFSAAMKVGNMALQAVEHCAVDLSGPTLAVYRKVAIIEAQSGRGIAQEQSIERLRRAVYLTKDVVLDSDAEILRTQITLVELALLKIEAEKMSRGDDEGTQDAANTVVSDISKTYQACRRRFGPRSPLARQALRIMCDALHASGDISRGLKMLDRFHESCSEESPAEEIDTIIALRIRSLPIEMSQVARAAEDQLADLGSRANARGCLERLEFEYRCWMDLDSQLMDAGDSLPRCGQAYYSRVMDSEMVEEAIETISKDIEAFDMVEAVERHLRILKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZI50</accession>
    <name>A0ABR3ZI50_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000018">
        <property type="protein sequence ID" value="KAL1899730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="466"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="575"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="466"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="485"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="591"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="640"/>
            <end position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="675" mass="77215" checksum="3060D670469E126E" modified="2025-10-08" version="1">MSQHTQNNSSSTISSCSYQSIEINNSHVGDSFFWALKSIESELQRMITEPHTRNLDRGKYVTMYNTPGTPDQTVFSPLHNINIAAMAKEAYKDIIDKPLTMAEWVSLIDKIQYAPGYRYQNEAKHETERLEKWLMSDAASLETKKAFLRSDIGHLRMAIVVRHLIRVRWSKLGVWNPIWGCPDGPNDEFKDQLSFWTWPWDGTIDAPGWENENGEIISPDDLYPEDVVELNASHPIARLMDMRLDQRRGDPVLHEVMMPPDEKSTMEYRMRFVISRPWMHFNMDRVTEEVRIKERLNKKQPNLCRVLAVDDNDIRDWMKANGEWSQSWDARSLIGWTWPGEASVGAFEDLDAINSMMLPWDQYERECLDACGFAGTPEQESGIGKAHERARETLDIQRQMLGFTFNQPHRIDTSRYNIALDSQISPRTWTATVKNEMMAPLQVLDWKIETKLSSPAGSEIIARLSRRENDESAKTEISGKFKRSIASTSSHRGQVKFDSTVQSPPSNNSPQKRRLDSPPPPSGCNQRQTHRNIKVKVDTEAAKLAPKFDEVRTRSDAEVMYPELLAALASYRARNENQPKPRTQSIITSTDTEEDTDVDMSDASSKALLARPSATVLRTGGRPIRPNHCRNKEQSTQRASSKRQRRQKAILRPKTSGVRASRRLMKAQPEYSGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ75</accession>
    <name>A0ABR3ZJ75_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA wybutosine-synthesizing protein 2</fullName>
            <shortName evidence="2">tRNA-yW-synthesizing protein 2</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TRM12</name>
        <name evidence="5" type="ORF">Cpir12675_000941</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4-demethylwyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = 4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36355"/>
            <dbReference type="Rhea" id="RHEA-COMP:10164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10378"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64315"/>
            <dbReference type="ChEBI" id="CHEBI:73550"/>
            <dbReference type="EC" id="2.5.1.114"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">tRNA modification; wybutosine-tRNA(Phe) biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102522">
        <property type="term" value="F:tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030382">
        <property type="entry name" value="MeTrfase_TRM5/TYW2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026274">
        <property type="entry name" value="tRNA_wybutosine_synth_prot_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245">
        <property type="entry name" value="TRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245:SF25">
        <property type="entry name" value="TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038972">
        <property type="entry name" value="Trm12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51684">
        <property type="entry name" value="SAM_MT_TRM5_TYW2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SAM-dependent methyltransferase TRM5/TYW2-type" evidence="4">
        <location>
            <begin position="121"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="122"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00049400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR038972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1900470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="422" mass="46957" checksum="98FD6447302FE086" modified="2025-10-08" version="1">MAPDRPSKTRRGVRDWRQCTKSIFFSSFPTSQLKQWAESLRLATPEELSLSLPKGYLTYEPLAIFPSGSLSSEPGTLLHLLTAEERDILWRIVLQELSKKSGMNLTHLAVNAGIPVHKEGKNQVSSESGHAATTSETAEDKNILRSPTGLRELYGHFGSADGSAYDFDEALWVWTRQNGIWQTWAPKWTMFSRGNVVEKARLLDFHKAQTAESSKFPHRILADLKTKTAVDMYAGIGYFVFSYARLGLRVLGWELNPWSIEGLRRGALRNGWAVKVVQGADLSALSTIEATSGNEQITIFAEDNCHAQLRLEQLRAANSKTPGKCLTVVHVNGGLLPTSEPSWASSFAITRISDKAWLHLHDNVGIDDIEARRQELEQRISAWAIEEGLGRTVAVEHTMKVKTFAPGVWHCVFDVYLSKGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJF4</accession>
    <name>A0ABR3ZJF4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="6">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PIN4_1</name>
        <name evidence="9" type="ORF">Cpir12675_000719</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043323">
        <property type="entry name" value="PIN4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45995">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13616">
        <property type="entry name" value="Rotamase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PpiC" evidence="8">
        <location>
            <begin position="32"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="126" mass="13371" checksum="072591C2C3B27C94" modified="2025-10-08" version="1">MAKKGGDVGKSKGGAAAKGSKADEKAGKVKGAQSINVRHILCEKHAKKEEALAKLAEGVKFDEVARQFSEDKARQGGALGWKTRGSLDPKFEEVAYALADSTTASPKIGEAKTEFGYHIIIVEGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJT1</accession>
    <name>A0ABR3ZJT1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNA helicase</fullName>
            <ecNumber evidence="4">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">DBP10</name>
        <name evidence="18" type="ORF">Cpir12675_000999</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000014">
        <property type="protein sequence ID" value="KAL1900315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17959">
        <property type="entry name" value="DEADc_DDX54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012541">
        <property type="entry name" value="DBP10_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033517">
        <property type="entry name" value="DDX54/DBP10_DEAD-box_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF8">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08147">
        <property type="entry name" value="DBP10CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01123">
        <property type="entry name" value="DBP10CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 18" id="KW-0347">Helicase</keyword>
    <keyword evidence="7 18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="10" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="17">
        <location>
            <begin position="97"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="128"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="16">
        <location>
            <begin position="345"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="22"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="342"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="632"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="845"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="13">
        <location>
            <begin position="97"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="644"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="675"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="867"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="924"/>
            <end position="936"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1900315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="936" mass="104189" checksum="93BFF82ED140988B" modified="2025-10-08" version="1">MGYHAKTLAQLPDNEIDIFDSLNTQDNDEHDGKKKRYNIETEDPEYGFDFDNMMNGEGKGDGGDGGEDDDEAFIALRQAAQFRKTTNIQGKSVKKGGGFQAMGINSNLLRAITKKGFSVPTPIQRKTIPVILAKKDVVGMARTGSGKTAAFVIPMIQHLKQHSARVGARALIMSPSRELAIQTLKVAKEFSKGTDLKSVLLVGGDSLEEQFSMMASNPDIIIATPGRFLHLKVEMRLDLSSIKYVVFDEADRLFEMGFAVQLTEILHALPLSRQTLLFSATLPASLVEFARAGLQDPELIRLDAETKVSPDLQSAFFTVKAEEKEGALLHILHDIIDMPTGTPEGAKRDFEKSKKRKGNPDAFGKGKPTEHSTILFAATKHRVEYLANILQHAGFAVSYVYGSLDQEARRIQVENFRCGRTNILVVTDVAARGIDIPVLKNVINYDFPPQPKVFVHRVGRTARAGQTGWSYSLVRDVDAPYLIDLQLFLSRQLIVGQTKNEVSFAKDIVVGSLKRRPIEDNHEWVAKLVSELHDMASIRQVAEKAERLYMKTRHSASAQSAKRAKELIASDNWTQLNMKFGIDTDPDSQALTKMLAKISGYRPSETIFEVARGSKSSSAEALEVMREIRRKVVPKNRQPKETNEEGVEEDGDHDDDMEADGDDDIPTQCAPADIPDSEMEDPSDASMSEDDNDDDLEVTISDPKAQRKNQLDFADPEVFMSYTPRTINAAEERGYGVHSGSQKGGFVEAARAVTMDLTNDDGAKSFGEPTRAAGMRWDKKNNKYVARANDEDGSRGSKLIVGESGVKIAASFKSGRFDRWKKAHHISMPRTGDTEKPSLARLAVSDVRSQSNNGNVMGGGRFKHKQEKAPKEADKWRDDYHVRKKRVSEARENRIGRFKDGQGSKKEVRGVDDIRKGRIEKEKKRLKNARPQRKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK15</accession>
    <name>A0ABR3ZK15_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Xaa-Pro aminopeptidase</fullName>
            <ecNumber evidence="5">3.4.11.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Aminoacylproline aminopeptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Prolidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Cpir12675_000866</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.</text>
            <dbReference type="EC" id="3.4.11.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the peptidase M24B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.9" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01087">
        <property type="entry name" value="Prolidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007865">
        <property type="entry name" value="Aminopep_P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001131">
        <property type="entry name" value="Peptidase_M24B_aminopep-P_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052433">
        <property type="entry name" value="X-Pro_dipept-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226:SF3">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE AN0832-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05195">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01011">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00491">
        <property type="entry name" value="PROLINE_PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminopeptidase P N-terminal" evidence="15">
        <location>
            <begin position="108"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1900729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="591" mass="66381" checksum="7ED950DD25DCBE8F" modified="2025-10-08" version="1">MTRSSGPRAVCPQYSSVSLCETNSLHIDLLTIQDNSKCENPLHAQAPIVPTTATTIVTAPTTVTKTSPDCIDYISRNYKPQNCRRRVPEVATFNAEAPEVVDAPFAKFPAKLHARKVADELYKAHRVSKGLIFLPGQPTTEYEDSDQGPRFRQRRYFFYITGANFPNCYVTYDIGQEHLILWVPYVEPRQVLWYGSTPSPEECLRNYDVDEVRFAAQLPEYLQDKLRFDLTLYLLHKDQAPHFDNEIVNSLHYRVNTSFLQECMDEARVIKTPYEVAMIRKACAISTLAHRQVAAQLLTLKNEREIEAVFQATCTASGARDQAYPIIAGSGVNASTLHYEENNAPLQGKELVVLDAGCEWNCYASDITRTLPISGSFSQEALDVYKVVDKMQQECLNSAKPGVLYYALHLNASRVALVELMDLGILHNGSAKEIWDAGTISAFFPHGLGHHVGLDVHDVSGRDRLLLLGEEKIKIRGYRSMKREIVTPESLSSAVGLFDAPPPPYHGRQALQPNMIVTIEPGIYFCREYIEGYFLSNPTHARFLNTKALERYYPVGGCRIEDDILITPNGNENLTPAPKGQEMLDIINGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKF4</accession>
    <name>A0ABR3ZKF4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Lon protease homolog 2, peroxisomal</fullName>
            <ecNumber evidence="8">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Cpir12675_000654</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Peroxisome matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 9 10">Belongs to the peptidase S16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="8"/>
    <dbReference type="EMBL" id="JAWDJO010000008">
        <property type="protein sequence ID" value="KAL1901165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19500">
        <property type="entry name" value="RecA-like_Lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.5270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="entry name" value="LON domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03121">
        <property type="entry name" value="lonp2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004815">
        <property type="entry name" value="Lon_bac/euk-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054594">
        <property type="entry name" value="Lon_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027501">
        <property type="entry name" value="Lonp2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00763">
        <property type="entry name" value="lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10046">
        <property type="entry name" value="ATP DEPENDENT LON PROTEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22667">
        <property type="entry name" value="Lon_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001174">
        <property type="entry name" value="Lon_proteas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00830">
        <property type="entry name" value="ENDOLAPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 8" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="2 8 9" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="14">
        <location>
            <begin position="8"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="Lon proteolytic" evidence="13">
        <location>
            <begin position="720"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="284"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="416"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Microbody targeting signal" evidence="8">
        <location>
            <begin position="920"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="285"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="312"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="active site" evidence="8 10">
        <location>
            <position position="813"/>
        </location>
    </feature>
    <feature type="active site" evidence="8 10">
        <location>
            <position position="856"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="477"/>
            <end position="484"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR001174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAL1901165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="922" mass="101335" checksum="522FDA20E0378A83" modified="2025-10-08" version="1">MSVGVDHLPLIPLLRGAVLLPGVIQRIPVSSKRPDVPSLLAALLEESALSSSDRIESIIGCVPVNPAVLGPTSAHHVDIQNNGDRADQHTSEVAFAKLQTSDLSFIGVTAKIMGIDGRGGLGDFTLRVEGLQRCKVKGVVKDRPFFEATNYIECLDKVNPKDKELHALFQTFKTLSRELVALLRVSSLLPPQGEALSGLPPLLTQRLDVFIAKKQIDECGQLADFMANIVESSYEEKLGVLGALDVKDRLKKVTIMLDRQVTTMKGNFKITAVTTFPAHILGLHNRSSQPTTNPHNPMMAIMPPGNKGGNGGDDDSDDEDSEISQLKKRLDEAKLPPDAKKLVDRELRHLRNTHPGGQEYANMINWLDTIADIPWTKVTEDRLGPETLVKARTQLDSDHYGLERVKRRLIEYLSILRLKQSINDDLDRKIQRTENELNTTNAEGTASPEDIVALNARLELLRRRCMQDKSPIMLLVGPPGVGKTSLARSVATALGRKFHRISLGGVRDEPEIRGHRRTYVASMPGVIVQGLRKVGVSNPVILLDEIDKLGKASNMGDPSAAMLEVLDPEQNNSFTDHYVGTPIDLSKVLFIATANNLEYIPPPLLDRMELIYLPGYTSHEKCHIAQKHLVPKQTRYNGLTDSQCVFNQKVIKKIIEGYTREAGVRNLEREIAAVCRGKAVEYADACDRDKIDVYRSELTPNDIERFIGSERYEEEIAMTSSRPGVVTGLVAYSSGGHGSILFIEVADMPGNGHLQLTGQLGDVLKESVEVALSWVKGHAFELGLTNDASTNIMHARDLHMHCPAGSIPKDGPSSGMAQAIAMISLFSNNAVPPDLAMTGEISLRGRITAVGGIKEKLIGAHRAGVKTVILPEQNRRDTKGLPQEVKDGLKIIYVNHIWDAIRIVWPDSKWAQNHIGSIESHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKY7</accession>
    <name>A0ABR3ZKY7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Alpha-1,3-glucosyltransferase</fullName>
            <ecNumber evidence="12">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ALG8</name>
        <name evidence="13" type="ORF">Cpir12675_000868</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the second glucose residue from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide intermediate Glc(1)Man(9)GlcNAc(2)-PP-Dol to produce Glc(2)Man(9)GlcNAc(2)-PP-Dol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>an alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-glucosyl phosphate = an alpha-D-Glc-(1-&gt;3)-alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:31307"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19502"/>
            <dbReference type="Rhea" id="RHEA-COMP:19521"/>
            <dbReference type="Rhea" id="RHEA-COMP:19522"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57525"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:132521"/>
            <dbReference type="ChEBI" id="CHEBI:132522"/>
            <dbReference type="EC" id="2.4.1.265"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:31308"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Endoplasmic reticulum membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the ALG6/ALG8 glucosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="12"/>
    <dbReference type="EMBL" id="JAWDJO010000011">
        <property type="protein sequence ID" value="KAL1900731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042283">
        <property type="term" value="F:dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004856">
        <property type="entry name" value="Glyco_trans_ALG6/ALG8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12413">
        <property type="entry name" value="DOLICHYL GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12413:SF2">
        <property type="entry name" value="DOLICHYL PYROPHOSPHATE GLC1MAN9GLCNAC2 ALPHA-1,3-GLUCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03155">
        <property type="entry name" value="Alg6_Alg8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 12 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="312"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="359"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="388"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="410"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="442"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="477"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1900731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="499" mass="56295" checksum="6E92C44C54DBE222" modified="2025-10-08" version="1">MDAYPSLLQCAVVAAAFKILLFPAKSTDFEVHRNWLAITNSLPIWDWYYENTSEWTLDYPPLFAFFEWAMSHIAHMVDPAMTVVSNLDYDSWQTVYFQRFSVIATELFLVYALQRYIEGAPPNLKRASQAAALSILLSPGLLIIDHIHFQYNGAMYGILIYSLVLARRQSGLLISGIAFAILLCMKHIYLYLAPAYFVYLLRVYCLSPTSIFTIRFKNCLALGASLVAVFGVAFGPFALKGQMPQVLGRLFPFSRGLCHAYWAANVWAICSFADRFLIYAAPRLGLTVREEALNSVTRGLVGDTAFAVLPDVSPRVCFLLTLFFQALPLIKLFRKPTWDNFIGAITLCGYASFLFGWHVHEKAILLVIIPFSLIALKDRRHFGAFRPLAVSGHVALFPLLFGAAEFPIKIVYTIFWLMVFLLAFDSLAPASSKPRIFLLDRFSTIYIAVSIPLLVYCSLIHGIIFGKQYEFLPLMFISNYCAIGVVGSWIGYMVVYWTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL87</accession>
    <name>A0ABR3ZL87_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Replication protein A C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_000653</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the replication factor A protein 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000008">
        <property type="protein sequence ID" value="KAL1901164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04478">
        <property type="entry name" value="RPA2_DBD_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040260">
        <property type="entry name" value="RFA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014646">
        <property type="entry name" value="Rfa2/RPA32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014892">
        <property type="entry name" value="RPA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13989">
        <property type="entry name" value="REPLICATION PROTEIN A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13989:SF16">
        <property type="entry name" value="REPLICATION PROTEIN A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08784">
        <property type="entry name" value="RPA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036949">
        <property type="entry name" value="RPA32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Replication protein A C-terminal" evidence="7">
        <location>
            <begin position="164"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="274" mass="29605" checksum="824E2707D998B925" modified="2025-10-08" version="1">MSGYGYGDDGGGFVQGGSQYQGSQGGGSGEKSYTRDSLRPVTIKQILECEESQMGPNPDFRIDGESVTQLTFVAQIRQYTRQNTAELFRLDDGTSMIDAKKFLSSTETNGDEPSAAEWEIDSWVRAYGRVKVFGGKRSINIHVVRPVESYNEVNYHMLEAAMVHLYYTRQAQGGGGGGGGGGGGDGMFVDDGGDAQMSNYGDANSKIMHASVPAKKIWKVISTAPRSNEGMRVEVMATNAGLDIDTSMGAAQELMSIGLLYNTVDENTFDIMDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLR2</accession>
    <name>A0ABR3ZLR2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TAFII55 protein conserved region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_000358</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08047">
        <property type="entry name" value="TAF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037817">
        <property type="entry name" value="TAF7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006751">
        <property type="entry name" value="TAFII55_prot_cons_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12228:SF0">
        <property type="entry name" value="TATA-BOX BINDING PROTEIN ASSOCIATED FACTOR 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12228">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID 55 KD SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04658">
        <property type="entry name" value="TAFII55_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01370">
        <property type="entry name" value="TAFII55_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TAFII55 protein conserved region" evidence="7">
        <location>
            <begin position="139"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="13"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="311"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="364"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="316"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="380"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="393"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1901668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="488" mass="54990" checksum="5137A54FC55D4351" modified="2025-10-08" version="1">MSEPHRPVLKIHLNTGARHQLPDESKTTTPTGTAPGRLILKSKRASIVTPTEVQSTPNLPLTTTKAGRLLKPSAKKREHDEYGDEEIPITVAEPPSKRKNTKQKQLNTRVKLTSRRPPMRPPGDGYDSEASDREIDPSIEEQIIFRMLPGEHCEYIRKAVEENKICSRKDGGVDFRIRWLPEDTRRAIVGVKGRLFVAFLLDLPTITEGMKSWDRKTFMKSTDISQILLVWKAVASEEEAKTTPLPPMVESGFKWPHGLTPPMHDCVKRRFAKIISRKEIEDKEAEVERLLAADRASLGSRFEWIDDRRPKTPADEYMEDEDAEGDVDDTYFSEGGVEDAEGEEDHMDLEALFEAELAANDGEMASPATNADGITPVTAVGSTPTTQVQESIEREEEAESDDDDDDDDDDDDDDMDGNESENEEVNNFKEEIAELKAQLKLKEADLLKPHVANSAILKKKVQANIKSLKDEIRLKMSYINQEEDENED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLV1</accession>
    <name>A0ABR3ZLV1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Saccharopine dehydrogenase NADP binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000699</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the saccharopine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051276">
        <property type="entry name" value="Saccharopine_DH-like_oxidrdct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286:SF5">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Saccharopine dehydrogenase NADP binding" evidence="2">
        <location>
            <begin position="13"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="441" mass="48308" checksum="ACF3978144695125" modified="2025-10-08" version="1">MTSYKDHSRQYDVVLLGATGYTGRYTCEYIVKEFPPYLKWAISGRSEQKLQKLANSLEELDSSRELPGMFSYEDSGVDTTLLIIIIAIEIYDTNNEALVALVRKAFIVVTCIGPYHIYGEPIFRACAESGTHYVDVCGEVVHTKKMSDLYSTDASQSGAIMLPQCGIESAPSDISTWALAQTLQRELGVATGPVTISLELHGSPSGGTLATVLSLLDSFSIADIRKAFMPYAWSPHSRHNPPVTPQSWWSRLTGLRKVPGLGLLTTSIAAHTDSALVERSWGLMQVVPSLRPFNYGPDFSFVEYFRPSGALHGVMVHLFAVAMQVVMAIPPLRALLRSRMTQPGDGPSREQANKETIEYRGIAIPSPDTTGKRAFSHARYAGPMYYLTGLLAMEAARVLLEVDTKLEGGVYTPACLGDHYTARLADHGFKLETSIVNADSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLW1</accession>
    <name>A0ABR3ZLW1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Chromatin modification-related protein EAF6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">EAF6</name>
        <name evidence="12" type="ORF">Cpir12675_000381</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the EAF6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015418">
        <property type="entry name" value="Eaf6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13476">
        <property type="entry name" value="CHROMATIN MODIFICATION-RELATED PROTEIN MEAF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09340">
        <property type="entry name" value="NuA4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="74"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="10"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="125"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="160"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU368022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1901690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="171" mass="18319" checksum="203B1BE50C5E377B" modified="2025-10-08" version="1">MVGAGTMPSMTEYRKEQARLRDLIEKQRQIAKKLAAVEETIAQKETNYLEATPNGNIIFGFDSYIKGINSAAQRKKQNAPDANRVFSRSSISYRPVVNGDATPGSSNPSFAATPTAYKLESGNATPTSTTGPVPSSGKAGKKKKAAAVNDDDSEVDASHPRKRINFGGGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZMI7</accession>
    <name>A0ABR3ZMI7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000519</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="165"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="316" mass="34544" checksum="E3E95EC7388E373F" modified="2025-10-08" version="1">MSPDIADNVPRTLDKVTRDDTELAGQAQSEGGVAKATTNSSTEETQTGAELKAAALLDELMSEEACGNIDGNGETADADRTGPNSPANNEEDAPLPNEPPLPNEPVSESTNNNAPLLPSEPTLGDDGWDYRWDPATNQYVFFNRFTGVEQLENPRLQEPSHPHQTQLSSGTITGSTTTNSADTPPPPPEILGYNPAIHGDYDPDAWYAKLDESQEPGISSSALHMNALDDGSQVAFNRFNGHFQTDGLGSERYSGDAKAKRQLHSYFDVDAAANAHQGRSLKAERQGQRLSKNELKQFKEKRKARKEEKRRAWLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN18</accession>
    <name>A0ABR3ZN18_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">V-type proton ATPase subunit G</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_000198</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the V-ATPase G subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005124">
        <property type="entry name" value="V-ATPase_G"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01147">
        <property type="entry name" value="V_ATP_synt_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12713:SF11">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12713">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03179">
        <property type="entry name" value="V-ATPase_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="28"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1902091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="112" mass="12143" checksum="688D3FDD6ADE1E23" modified="2025-10-08" version="1">MSAQSSAGIQTLLDAEKKASQIVQEVRTKRVKQARDEAKKEIDNYRARKDAEFQAFTAEHSQGNKEAEAEAQEDAQAKIAEIKESGKQGQVKVVGDLLSAVFDVKPVAPSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN29</accession>
    <name>A0ABR3ZN29_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA-directed RNA polymerase subunit beta</fullName>
            <ecNumber evidence="9">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">RPB2</name>
        <name evidence="18" type="ORF">Cpir12675_000200</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="entry name" value="RNA polymerase Rpb2, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007646">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007647">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04566">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04567">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9 18" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 9 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase beta subunit protrusion" evidence="14">
        <location>
            <begin position="37"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="13">
        <location>
            <begin position="242"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="15">
        <location>
            <begin position="507"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="16">
        <location>
            <begin position="606"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="17">
        <location>
            <begin position="707"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="11">
        <location>
            <begin position="787"/>
            <end position="1159"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="12">
        <location>
            <begin position="1161"/>
            <end position="1253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="145"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="951"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="151"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="952"/>
            <end position="976"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1902093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1261" mass="143038" checksum="575CCD3D2E59BC5F" modified="2025-10-08" version="1">MEDYDDGYDYDEYGEADEGITPEDCWTVISTFFETKGLASQQVDSFDEFTTTTVQDLVSEYSHITIDQTNPPSHDGRAFALRRYDVDFGKVMVSRPSITEQDGKESTLLPYECRERNLTYASPLYLKITSKVRLAVESPIPLNELTDDQQDDLKRTGEHPTRIEWEDEAVDDNITEGKSDDMKDVVFIGRMPVMVKSRICHLRRENDEGLFLLNECPYDQGGYFIINGSEKVLIAQERSAANIVQVFKKAQPSPYSYTAEVRSALEKGSRLISQLALRLYNKSAASKSVSFGSTIRTTLPYVKSDVPVAIVFRAFGVVSDEDILNHICYDRNDTQMLEMLRPCIEEAFVIQDREVALDYIGKRGQSYGLTRDKRIRAAKDLLQKETLPHISQTEGSETRKAFFLGYMVHKLLQCSLGRRDVDDRDHFGKKRLDLSGPLLAKLFRNIIRRINSELASYMRMCIQQNKRFLMVNGIKPSALSNGLKYSLATGNWGDQKKAASSTAGVSQVLNRYTFSSTLSHLRRTNTPIGRDGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLMCFVSVGTPSDPIIEFMINRGMEIIEEYEPLRYPNATKVFVNGVWVGVHQDPKHLVTEMTETRRRSYLPNEVSLVRDIRDREFKIFSDAGRVMRPVFVVQREADPDRGLEAGQLVLTKDHVNSIREEQENPTGGPREFGWNWLVNQGVIEYLDAEEEETTMICMTPEDLDTYRLRKSGIDVPEEPMGDDDINKRLKTNIKPTTHMYTHCEIHPSMILGICASIIPFPDHNQSPRNTYQSAMGKQAMGFFLTNYSRRMDTMANILYYPQKPLATTQSMEFLKFRELPAGQNAIVAIACYSGYNQEDSVIMNQSSIDRGLFRSLFFRSYTDCEKRVGINMVERFEKPFRNETLRLKHGTYDKLDEDGIVCPGLRVSGEDIIIGKTSPLGQESQEMGQRTTQHTQRDASTPLRSTENGIIDSVVMTTNQDGMRYVKVRVRTTKVPQIGDKFASRHGQKGTIGVTYRQEDMPFTCEGITPDIIINPHAIPSRMTIAHLIECLLSKVATLKGMEGDATPFTDVTVDSVSALLRQHGYQSRGFEALYHGHTGRKLRAQVFFGPTYYQRLRHMVDDKIHARARGPVQIMTRQPVEGRARDGGLRFGEMERDCMIAHGAAAFLKERLFEVSDAFRVHICEICGLMTPIANLSKQSFECRPCKNKTKIAQIHIPYAAKLLFQELQSMNIAARMFTDRSGATIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNI5</accession>
    <name>A0ABR3ZNI5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Coatomer subunit delta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">RET2</name>
        <name evidence="13" type="ORF">Cpir12675_000336</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9 10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9 10">Cytoplasmic vesicle</location>
            <location evidence="9 10">COPI-coated vesicle membrane</location>
            <topology evidence="9 10">Peripheral membrane protein</topology>
            <orientation evidence="9 10">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9 10">Golgi apparatus membrane</location>
            <topology evidence="9 10">Peripheral membrane protein</topology>
            <orientation evidence="9 10">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09254">
        <property type="entry name" value="AP_delta-COPI_MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14830">
        <property type="entry name" value="Delta_COP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027059">
        <property type="entry name" value="Coatomer_dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10121">
        <property type="entry name" value="COATOMER SUBUNIT DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10121:SF0">
        <property type="entry name" value="COATOMER SUBUNIT DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 9" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="4 9" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6 9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="12">
        <location>
            <begin position="295"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="155"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="201"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1901646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="532" mass="58746" checksum="3AE5E0AEE9A80A65" modified="2025-10-08" version="1">MVVLAASICTRGGKAVLSRQFHEMPRSRIEGLLASFPKLADSGTQHTTVEQDSVRFVYQPLDELYMVLITNKQSNILQDIDSLHLFAQVVTSTCRSLDEREILNHAYDLLSAFDEIVTLGYRENLTISQIKTFLEMESHEERIQEIIARNKELEATEERKRKAKQLELQRKESARAGRGPGSMGGMGGGMGGGMGGGMGGPRTPTYSSYNSPSSSRPAAQDTFDSYEAEKNKTFQKSTFKGKGMQLGKKSKTTDMFERVRGEMGSEIDNTPLVAPTPQAPSHAAAPEEHHSAVDRDVIHTTVSETISAKITRDGTLNSMSVNGDLSLRVSDASMTKIKLDVKANAKHGAQFRPHPNVDKNLFNSSRIIQMSNTARGFPVNASVGVLRWKASPKVDDTSACPITFTVWINKDSDKYSLTVEYELTGGEDLNDVAIHIPYSSEPVVTSYDAQYEMDGEILTWTLGEVTQANSSGSFEFEAEANDEEGFFPMNVRFTKPTPFVDVEVKTVSLVEEDEEVTFSQESKTVAENFLIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP02</accession>
    <name>A0ABR3ZP02_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Redox protein fmp46 mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_000600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Putative mitochondrial redox protein which could be involved in the reduction of small toxic molecules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FMP46 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000007">
        <property type="protein sequence ID" value="KAL1901234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012882">
        <property type="entry name" value="Fmp46"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28071">
        <property type="entry name" value="REDOX PROTEIN FMP46, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28071:SF1">
        <property type="entry name" value="REDOX PROTEIN FMP46, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07955">
        <property type="entry name" value="DUF1687"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="129" mass="13908" checksum="9AF302CC571D39A2" modified="2025-10-08" version="1">MIRFPRAIDIVTLFSKAGSPASTRIAQSLKNAAIASANADSNMRVPFEVDVTEQAPTEDQVRTILSYVGANGISSIISGATSEAEALKKYKLAPESFRRPVVVDWNNAKVVAGENESEILKMVNAQKQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ72</accession>
    <name>A0ABR3ZQ72_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein mL54</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_000359</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the mitochondrion-specific ribosomal protein mL54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013870">
        <property type="entry name" value="Ribosomal_mL54"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28595">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L54, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28595:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08561">
        <property type="entry name" value="Ribosomal_L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1901669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="199" mass="21634" checksum="7B363DA679D47D09" modified="2025-10-08" version="1">MILRNCLIRASTAARQPAVFRAFSASSLRLSATTEAASSEATTATPSETDTSALENNSASSCPAGTVLKGLNFLNGQQDPMALPDEAYPAWLWKCLEVKERVKDESEDLAAIEFSKSKKQRRIAAKKTRQIEAELMASGDMSALAPKIPLHEQSINLPGSLEGGFDDSMEAAEARAELKKALRKDRKAKIKEANYLKTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YBL0</accession>
    <name>A0ABR3YBL0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000499">
        <property type="protein sequence ID" value="KAL1885341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052400">
        <property type="entry name" value="Zn2-C6_fungal_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN ECM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657:SF7">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN ECM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="263"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1885341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="476" mass="53518" checksum="3C0E5DD5B95BFC58" modified="2025-10-08" version="1">MDPNLNFNLNMPSMLFQGSAAAYSFESPPNPNYGGLDIEDASVGSVSVDGGSQSPPDMLSSAEGGGCGGSTGSASSSRPEVALLRKKKERRGHTKSRRGCFNCKRRRIKVTHQPHNQIPLFSLLDMRFFQHFLAHSPNSHARVWSYQVPYLCHMYDYLMHAVLGLAATDLVTTDPSLNHIALSHRHKAVQALKRRLNDVKRVSGSMEETNALIATCYALTHQSVLLDDGMVEFMVFVRGILIVGMHMWMKGLSPIFSSLQQSTTSPPIHPATTTASATTSSSQHYQPHHHHHSHHRPPALPLLSRHWIDMASTAVSTLQSLCHEPLEIEYQHLLSELVATLYVSSDQACKVLRTQYRWWMTMPHHQFCKVINPTNQVMVLLNTHWIGLNQMLAAVADPNRSTRQHHQQSQQGGNSRHGGSHHHHGYLSTIQLGGFKWLKYTNRLVDYTHQFYNTWPTWVEQQLLRDPNVFSSSSPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YCF2</accession>
    <name>A0ABR3YCF2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_006961</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000456">
        <property type="protein sequence ID" value="KAL1885991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12193">
        <property type="entry name" value="bZIP_GCN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13044">
        <property type="entry name" value="ACTIVATING TRANSCRIPTION FACTOR ATF 4/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13044:SF14">
        <property type="entry name" value="CRYPTOCEPHAL, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="8">
        <location>
            <begin position="242"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="189"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="267"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="197"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="234"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1885991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="323" mass="34371" checksum="2DD3F9B4EA17978A" modified="2025-10-08" version="1">MLYAERHFFRPAQCRNGCINSGSPIITTDTTPISNGNYSSSGPGVLVQGLVDSDFATPSATTTTSSTSSSSNSSPVVALELNFDVNALGGANESHWPADALQACEFSSADILNLPFSDFSGNLDAFDQESSFLLNDLSASFINQFTSSDFQFPSLSAPASAPPVTITTDIPMNHISFAQTQISLNSSVRSSASSSVSPPPCDPPPTGASSIIIRNASPIAASKSGRKRSRTSDNLDDEDNEDEAAVVRRQKNTLAARKYRQKRLDRIKELEDALAEVTGDRDDLRIRLARQEAETKALKALMAQLAPAASVITAAPSVTAKEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YDD1</accession>
    <name>A0ABR3YDD1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_006954</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000449">
        <property type="protein sequence ID" value="KAL1885995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17356">
        <property type="entry name" value="MFS_HXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF61">
        <property type="entry name" value="HIGH AFFINITY GLUCOSE TRANSPORTER RGT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="343"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="404"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="443"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="479"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="28"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1885995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="554" mass="60548" checksum="80F762DF14E91A12" modified="2025-10-08" version="1">MGGGGAVSMGTADLSRIEAPVTFKAYLTCAFAAFGGIFFGYDTGWMSGVLAMPFFIRLYTGIDYDESSPDRTPIGVPPKEFSLPSWQKSLFTSILSCGTFFGSLIGGDVADWIGRRLTIIFGCLIFSIGCVLQVVSTDQTVLFVFGRLVAGLGVGFVSAVIILYMSEIAPRKIRGALVSGYQFCITVGILIANCVVYATEKRNDHASYRIPIGVQFIWAFILAVGLFFLPESPRFFVKKGKVEAAAEALSRIRGQPVDSDYIKDELAEIIANHEYELEAITDTSYVGSWAACFKGSITEPSSNLRRTILGTVLQMCQQLTGINFIFYFGTTFFQQLGTISNPFMISLITTLVNVLSTPLSFWSIERFGRRFLLIWGACGMIVAQFIVALIGVTEGRPSVNNDNAVKAMIAFICINIFFFAVTWGPAAWVIVGETFPLPIRSRGIGLSTASNWCWNTVIAVITPYMVGDDKNSANLGAKVFFVWGSLCILSLTFAYFFVYEMKGLSLEQVDQMMQETSPINSASWVPSKTYAADRGYVAAQSEKAGGSRVDVESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YDF6</accession>
    <name>A0ABR3YDF6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Mitochondrial carrier C29A3.11c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_006950</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000447">
        <property type="protein sequence ID" value="KAL1886001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF9">
        <property type="entry name" value="CARRIER PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G06390)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="17"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="126"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="241"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1886001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="339" mass="37270" checksum="2F5C003F20368F1A" modified="2025-10-08" version="1">MLALSIQTLGEQPKEFLRKYHVEVAACTSSVVSTTTAFPLDSIKTRMQTYRYPSVAECARQTYKSEKLRGFFRGVAAPVMSVTVVRTCSFSVYTRAKKFYSSLFEKAFNYNVLDHVARPGTYPNPYTIACFGASGATAGALVSFMACPFELTKLSAQVSVLLASKVGQTGDSEKKRLAESYKNKGTFQTMAHILRNRGPLGLYTGFNLHLVRDTIGTGVYFMVYESGKQITSSIFGSNPDNNKLSVAVAGGLCGVLSWAVIYPVDSVKSIYQRNSLTSLRGEKVPPAPRVQFFKRNMYRGLGVSITRSAVVNAVFFTFFEGIKKDISKGLSQDEVHKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFE9</accession>
    <name>A0ABR3YFE9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SKY1</name>
        <name evidence="12" type="ORF">Cpir12675_006757</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000368">
        <property type="protein sequence ID" value="KAL1887011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14136">
        <property type="entry name" value="STKc_SRPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051334">
        <property type="entry name" value="SRPK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634:SF9">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 12" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="154"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="311"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="23"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="58"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="100"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="329"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="367"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1887011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="611" mass="67232" checksum="C7411A508EFB14B2" modified="2025-10-08" version="1">MADVATNGPTLSHIKAGDASYPNGSTNGSTNGIGNIPQSNSGPVAASNSKNSSIADQSSTTNNATDAADYLDADNAASSSDTAAAKKRKKEALKPIITSDAGNTQNSPDSPNSVSSADEGTGTENTPDEEDSEDYCYGGYHPVTIGENFNNDRYTVVRKLGWGHFSTVWLSRDNKVGKHVALKVVRSAPHYSETAIDEIKLLNKIVQANPDHPGRKHVVSLLDSFEHNGPNGTHVCMVFEVLGENLLGLIKRWNHRGIPMAYVKQITKQVLLGLDYLHRECGIIHTDLKPENVLIDIGDVEQIVKKVIKSDTNDKENNRNGRRRRRTLITGSQPLPSPLNTSFNHNGNPFSSGTASLGQVLDSNGPTKDDALEEQQKQREKTADILSKDLSDALSLDKLTPSDKRKAEELFSSEIISVKIADLGNACWVNHHFTNDIQTRQYRSPEVILGGKWGASTDVWSMAAMVFELITGDYLFDPQSGTKYGKDDDHIAQIVELLGPFPRSLCMSGKWSLEIFNRKGELRNIHRLRHWALPDVLREKYQLQESEATEISSFLVPMLELIPERRANAGGMAGHRWLEDTLDMKGIKIEGLEVGSQGEKIEGWACETRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFF4</accession>
    <name>A0ABR3YFF4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61</fullName>
            <ecNumber evidence="1">2.1.1.220</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">tRNA(m1A58)-methyltransferase subunit TRM61</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_006764</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.220" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000370">
        <property type="protein sequence ID" value="KAL1887001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014816">
        <property type="entry name" value="tRNA_MeTrfase_Gcd14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12133">
        <property type="entry name" value="TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12133:SF1">
        <property type="entry name" value="TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51620">
        <property type="entry name" value="SAM_TRM61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="403"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="405"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="418"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00033309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="449" mass="49656" checksum="3ACE12736519710A" modified="2025-10-08" version="1">MYTNNGLEYDTLLLHQKSPTGGKFTLTPPIRPNETLKIAYDGELSTDLLLQRNILDAVTDSRGRIVDIYEPTLPAYVHHAPSRLATPIYAQDANLITSLFDLHPDPDPAAAPIEIFEAGTGIGGLTLHLARAIHAANPPVPAALRHALVRGDYKLPSVRDNSNEPLVEDHHEMTFADPSLQAMHDEYLALRRAVVHTLDVRHSHSRYAHKMVRHFRQAQYLLDVSFHVAEIQTYLEQRLAETHGKPFLTHAFLDLPEPEEHIHAVMQALKPDGTLLVFAPSITQIACVVKWVGGGAERKPLRLEKTLELPMATNNETSLRIGSGGKEWDVRYVKTKKALLEASKEVSADEATTASAKEDVLVCRPMVYQRIVGGGFIGVFRKLLDQSDRQVFEGSLKQFKRKSRRANEDTIEKVEMASETTSGGSAGVNTSTGAEASVGINGHVEKEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFQ5</accession>
    <name>A0ABR3YFQ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_006678</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000349">
        <property type="protein sequence ID" value="KAL1887138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033140">
        <property type="entry name" value="Lipase_GDXG_put_SER_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23025:SF3">
        <property type="entry name" value="HORMONE-SENSITIVE LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23025">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01174">
        <property type="entry name" value="LIPASE_GDXG_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="218"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="468"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="366"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="635"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="717"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="417"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="677"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="754" mass="84742" checksum="8A3EE7475919F2AB" modified="2025-10-08" version="1">MIDHVLGRPSARSRRLQVLAVLSFWTMYLKRGSKHGPPFARILSKFFTRRLTPWQIVTLTIMSLYAAQNFSSLVGLSSPDPLSKMYEAGFFRATWVLTALDAGFWTAMKIKSRRLRDLASVIFTLFYLFAADMADEKVRRVRGNLTIDHMRVSWNKSTSPYLNFLQGLIRPRFMRSSPRQLRIARPSGSDYTEPVTAWLYFDGTLAELRKHRRVLVDIPGGGFVAMDPRCNDDKLGCWASKTGMPILALDYRKAPEFPYPYALNECFDVFTMLVRTKGRCIGLAGTEIPKITISGDSSGGNLAVGTTLMIIERTIGHLSATERNSDLPLPEGLLLFYPSLDMNIGSWMSDEEMSLIRDRSMRRTNRPIVRRKTMQYSSLVGTPHHSDDEDASPPAEKVQKKLPERFQTPRKTRKTKASNAATATSTDFPVPGGSSQTAPEPASTEASATIHRASSFHPQPLRTRLAMSSKISYFSDRVLTPEMMRAMVIMYIGPHNRPDFRTDYLLSPTIAPDSLLSHFPKTFFLTGERDPLVDDTVIFAGRLRQARRYLFDLDAADPENISQHHPDDNYTESDILEMTLLPGISHGFLQFPALYPPAWELLERSAGWIEQSFQCSPGIRRREIRRRDFHQRQAAARAALTDYTTDEEAEDKPLEMNLKRKLRPQQQSPSARKGDGASSSDTMVASQQDGLGKAQGVLPNGSNEPVAWKHKIERLVAKTSDGAKPNLGRLNSEDDLVGRRMQGLTSGLTGLDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG04</accession>
    <name>A0ABR3YG04_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">U3 snoRNP protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">UTP18_1</name>
        <name evidence="7" type="ORF">Cpir12675_006620</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000336">
        <property type="protein sequence ID" value="KAL1887260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01941">
        <property type="entry name" value="YeiC_kinase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1790.10">
        <property type="entry name" value="Indigoidine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022830">
        <property type="entry name" value="Indigdn_synthA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007342">
        <property type="entry name" value="PsuG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42909:SF1">
        <property type="entry name" value="CARBOHYDRATE KINASE PFKB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42909">
        <property type="entry name" value="ZGC:136858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04227">
        <property type="entry name" value="Indigoidine_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110581">
        <property type="entry name" value="Indigoidine synthase A-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="6">
        <location>
            <begin position="423"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="6">
        <location>
            <begin position="715"/>
            <end position="771"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1887260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="787" mass="84005" checksum="3535D34F29355B7C" modified="2025-10-08" version="1">MRVHLLRSAVRSRSSGLPQFSPSSVYTSQQHRWSSSSLGSLRKILHISDEVAEAIATKKPVVALESTIYTHGALQTGLANELEQVVRQNGGIPATIGLFAGKPTVGLTPDEIETMIAEGGAMKVSRRDIAYLAGMGISGRKIHGGTTIAGTMILARLAGIRVFGTGGLGGVHRGGETSLDISADLTELGRTRVAVVSSGCKGFLDIPRTLEFLETQGVLVSTFADGRTGTSVDFPAFWARESGSKSPSVVTTEAEAAAMILAQENLGLESGLLFANPIPTMAEIPKARMEGIISTALREAEEKGFTGNKNTPYVLGRIRELTSEDSVRANLVLVNENVKRATKIAVELAKLETPGEKAFASAAWSRHPKPVPVTPSPAGHFVNTGSGADILVAGSVALDLSCDYMGGWVSDRPNQIQPQMHTSNPACINQSVGGVGHNVALAAHLVSEHTNVRLCSLIGDDVAGNTVLSSLRASGLDTTYVRQLGPEYAGSSRTAQYVSINDGNKNLVMAMADMGIFTHHSFPDYWKSAVAGASPRWVVVDGNWSETDIRAWISVSKECDCYIAFEPVSTAKASRLFGADSNNIPLGLYPSPSIDIASPNNYELKAMFGAARANGHLESIPWFSVVDSFNLRGGARDRFVQMTNVSITDAGIPQQTLQLLPYIPTLLTKLGSEGVLLTQILTPADPRLKDPNEMRYILSRSDDHPLVGGVYMRLFPPVERVENVVSVNGVGDTFLGVLIAGLVQGGKVQNLVDVAQKAAVMTLKSHQSVNPDLRHLDEELKLAVTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG54</accession>
    <name>A0ABR3YG54_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">serine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Seryl-tRNA synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Seryl-tRNA(Ser) synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SES1_1</name>
        <name evidence="10" type="ORF">Cpir12675_006817</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000384">
        <property type="protein sequence ID" value="KAL1886950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="entry name" value="Serine-tRNA synthetase, tRNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015866">
        <property type="entry name" value="Ser-tRNA-synth_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11778">
        <property type="entry name" value="SERYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02403">
        <property type="entry name" value="Seryl_tRNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001529">
        <property type="entry name" value="Ser-tRNA-synth_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="tRNA-binding arm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="9">
        <location>
            <begin position="189"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="59"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1886950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="350" mass="39912" checksum="6CB8AE1F88510284" modified="2025-10-08" version="1">MLDIQDFITERGGNPDAIRASQKARGASVEIVDEIIELWQDHRKTLYAATQLGSKINAVQKEIGAKKKAKENADELLQQKIALEKEKKELLNAAEEKQTVLRNKVRTVGNIVHSSVPVSMTEDDNETIRTWAPEGHIIEKKSELSHHEVLARLDGYDPERGVKVMGHRGYFLRKWGVFLNQALINYGLEFLHNKGYTPLQTPQMMVKDYMAKTSQLSQFDDELYKVSDGEPQNDKYLIATSEQPMSAFHAGEWLLTSQLPLKYAGYSTCYRREAGNGKDAWGIFRVHQFEKVEQFVLTDPEKSWEAFDEMINSSEEFYQSLGLAYRVVAIVSSELNNAAAKKYDLEAWFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGU1</accession>
    <name>A0ABR3YGU1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006797</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000377">
        <property type="protein sequence ID" value="KAL1886976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF6">
        <property type="entry name" value="MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15050)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1886976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="138" mass="15379" checksum="BE6B041AE3DAB758" modified="2025-10-08" version="1">MTGAVESTIAGPELVFSTTDTPSTTAPPPASATPTPALTQQPKPSSYPQARIPLVDNHIDEPRAVRVAVIGWRWAFGTWFVNVYQSTFEPNTQWSDGVSYGAEIRDYWQSVARKHNVYDLVKLQHHVQDLLWDENASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH62</accession>
    <name>A0ABR3YH62_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Trifunctional dihydropteroate synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">FOL1</name>
        <name evidence="16" type="ORF">Cpir12675_006472</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(7,8-dihydropterin-6-yl)methyl diphosphate + 4-aminobenzoate = 7,8-dihydropteroate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19949"/>
            <dbReference type="ChEBI" id="CHEBI:17836"/>
            <dbReference type="ChEBI" id="CHEBI:17839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:72950"/>
            <dbReference type="EC" id="2.5.1.15"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>6-hydroxymethyl-7,8-dihydropterin + ATP = (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11412"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:44841"/>
            <dbReference type="ChEBI" id="CHEBI:72950"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 7,8-dihydrofolate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">In the C-terminal section; belongs to the DHPS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000306">
        <property type="protein sequence ID" value="KAL1887626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00739">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00483">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.560">
        <property type="entry name" value="7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="entry name" value="Dihydropteroate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045031">
        <property type="entry name" value="DHP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006390">
        <property type="entry name" value="DHP_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000550">
        <property type="entry name" value="Hppk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035907">
        <property type="entry name" value="Hppk_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01496">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01498">
        <property type="entry name" value="folK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941">
        <property type="entry name" value="FOLATE SYNTHESIS PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941:SF1">
        <property type="entry name" value="FOLIC ACID SYNTHESIS PROTEIN FOL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01288">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55083">
        <property type="entry name" value="6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="Dihydropteroate synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00792">
        <property type="entry name" value="DHPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00793">
        <property type="entry name" value="DHPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00794">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pterin-binding" evidence="15">
        <location>
            <begin position="169"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1887626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="448" mass="49023" checksum="9F6621B9BFD8AB32" modified="2025-10-08" version="1">MGDRFAEIERACREIEKRGIRVKRTSSLWETAPMYVIDQDRFVNGACEVETHLGPMELLDALQDIENTMGRHKVIDKGPRNIDLDILLYGDQKIHNDRLNVPHIGIREREFVLRPLAELIPDKPLYPEKPWMLVQDYLNKLPLDKNLSPLIPLSPTMEPISSFKATRRTHVMGILNVTPDSFSDGGVNTRSSLPARISSAIASGATILDVGGQSTAPGTPEVTTDEEIARVLPAIHAIRSLPEGKSVAISIDTYRAAVAKAAVKAGADIINDVSAGQMDPEMLHTMAQLECTVCLMHMRGTPATMQGMTDYTASDGVVGGVASELVARVRAAEKAGIRRWRIILDPGLGFAKTPRQNIRLLGALNELRSWPGLVGLPWLVGASRKGFVGRATGVKHPAERIWGTAATVAAAIQGGADIVRVHDVKQMAQVARMADWIWRLVDSKKEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHL1</accession>
    <name>A0ABR3YHL1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L23A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL23A</name>
        <name evidence="5" type="ORF">Cpir12675_006851</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000393">
        <property type="protein sequence ID" value="KAL1886924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00337">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_uL14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019972">
        <property type="entry name" value="Ribosomal_uL14_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_uL14_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006344">
        <property type="entry name" value="PRK08571.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="50S/60S RIBOSOMAL PROTEIN L14/L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761:SF8">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00049">
        <property type="entry name" value="RIBOSOMAL_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1886924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="139" mass="14654" checksum="703AD9EF3A2D845E" modified="2025-10-08" version="1">MAKISRGAPGGKLKMTLGLPVGAVMNCADNSGARNLYIISVKGIGARLNRLPAGGVGDMVMATVKKGKPELRKKVHPAVIVRQSKPWKRFDGVFLYFEDNAGVIVNPKGEMKGSAITGPVGKEAAELWPRIASNAGVVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHR5</accession>
    <name>A0ABR3YHR5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nucleolar GTP-binding protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">NOG1</name>
        <name evidence="9" type="ORF">Cpir12675_006572</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the biogenesis of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
            <location evidence="1 6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000326">
        <property type="protein sequence ID" value="KAL1887368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01897">
        <property type="entry name" value="NOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024926">
        <property type="entry name" value="NOG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041623">
        <property type="entry name" value="NOG1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010674">
        <property type="entry name" value="NOG1_Rossman_fold_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012973">
        <property type="entry name" value="NOG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45759">
        <property type="entry name" value="NUCLEOLAR GTP-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06858">
        <property type="entry name" value="NOG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17835">
        <property type="entry name" value="NOG1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08155">
        <property type="entry name" value="NOGCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038919">
        <property type="entry name" value="NOG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="OBG-type G" evidence="8">
        <location>
            <begin position="170"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="546"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="555"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="580"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="602"/>
            <end position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR038919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1887368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="662" mass="75010" checksum="47A530C947F801EA" modified="2025-10-08" version="1">MSLRTSFKDIPPVPTSQEFLDIVLSGTQRRLPTQIRSGFMISRIRAFYTRKVKFTQETFSEKFSAILESFPRLTSCHPFHRDLFNTLYDQDHFKIALGQLSTAKGLMETISRDYVRLIKYAQSLFQCKQLKRAALGRMATICKRLKDPLLYLDQVRQHLGRLPSIDPNTRTLVICGFPNTGKSSFLRSISRADVDVQPYAFTTKSLFVGHFDYKYLRFAAIDTPGILDHSLEEMNTIEMQSVTAIAHLRSVILYFMDLSEQCGYPVQAQINLFKSIKPLFSNKIVFIAINKIDIARPDGLDPELKSQLDALLKPGETELLELSCNSGEGVQEAKNAACERLIAERVSQKMKAGTGAAGAISGRLAEVMSRIHVATPMGGQTLETFIPEGIKNLKRYNKNDADRRTLARDIEEQNGGAGVFNVDLRADWMLKNPEWKYDKIPEVLDGKNVYDYVDPEIETKLQALEDEEERLEAEGFYESEDEEYNDEQQSIMKKAEMIREKQAMIRNEARMKKRLKNQAIIPRSARKVPLSELDEGLDVLGVDTTDIKSRAKQDPSSAPRGRGRSRAGTADPDAMDMDGGDDRTPRERIRAMSRTRSVSRVNRREDGVQTAESRTKTERLAKLGQKKMNRMARQGEADRHQVASLSKHLVAGKRGIGKNDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHW7</accession>
    <name>A0ABR3YHW7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000289">
        <property type="protein sequence ID" value="KAL1887919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="355" mass="38318" checksum="A7C92F1D3CDDF98F" modified="2025-10-08" version="1">MHQIASFIVKRGLGAADDVDVDMASLKDSLPEWTGLLFGLEFAILLPVIFWATYTLSRVYATLAMIEDEAAPTYSRLPSIPIKTESDVVTKDPSAPLFDTTPITTNVCRTARHLKTFGGFRACFRGFVCMTLSNLVLSLVTCSLMLLLPAALKPFCSLAGSLAVAQLMTAWVHIIMTPGSSRSWFKRMPAFGPTMRATSRAIVLNWAATNACVAGYTLIRSHMLACSAHHAAAVAAATGVDPATPTPDARFVLLDIAMAVMYALIVVPTEVLLARSRASLLPAEEDSIINFDRSLGGHVTETGVVSLVAVWKSVSATAWKRIAKFHIRIFAVAASVLVPVTAMIAMQLYVLRNMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJF5</accession>
    <name>A0ABR3YJF5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Chitin-binding type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_006343</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000285">
        <property type="protein sequence ID" value="KAL1887992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11618">
        <property type="entry name" value="ChtBD1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018371">
        <property type="entry name" value="Chitin-binding_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF2">
        <property type="entry name" value="CHITIN DEACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00187">
        <property type="entry name" value="Chitin_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00026">
        <property type="entry name" value="CHIT_BIND_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 8" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="7" id="KW-0170">Cobalt</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Chitin-binding type-1" evidence="10">
        <location>
            <begin position="28"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="39"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="44"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1887992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="182" mass="19467" checksum="43D338ED277B675E" modified="2025-10-08" version="1" fragment="single">TDFGRCDPVSDEKEDKAPKIAELAPSPDGSCGGETGFTCTGSNCCSKWGWCGSTPEFCGAGCQSGFGRCDTLSAAVKPRVAAKPRSMIKSRAEKSVAQSFKEAFENGNEDVENGGQWYVDPETGLFWTWDTPALVERKFAEIIAARGLGGVAGWSLAEDSYDWRLVAAMKKGVESMNSANQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YK56</accession>
    <name>A0ABR3YK56_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="14">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">DNF1</name>
        <name evidence="18" type="ORF">Cpir12675_006243</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 14">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="14">Membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="14"/>
    <dbReference type="EMBL" id="JAWDJO010000270">
        <property type="protein sequence ID" value="KAL1888247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02073">
        <property type="entry name" value="P-type_ATPase_APLT_Dnf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF180">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE DNF1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 14" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="693"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="738"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1323"/>
            <end position="1339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1351"/>
            <end position="1372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1402"/>
            <end position="1423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1443"/>
            <end position="1461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1468"/>
            <end position="1489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1509"/>
            <end position="1527"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="16">
        <location>
            <begin position="311"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="17">
        <location>
            <begin position="1288"/>
            <end position="1537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="188"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="470"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1561"/>
            <end position="1631"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1657"/>
            <end position="1695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="55"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="82"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="188"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="278"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1614"/>
            <end position="1631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF16209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAL1888247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1754" mass="197473" checksum="3ACB0B10D3C87896" modified="2025-10-08" version="1">MSSFNQSQGQADAVDEDSSHARHPQINSQQPSTAQRHADIAYAQPSGLDDYGFNEPNNPDETHQFQSQPHSRHGQEQRPQEQHSPQSQQHPPSQQQQPPYPIDSPEYPDLYPQSQQHQLPPPQIEIEDENNIRTTQVDYYDPNHTSQPHGFSTDAAIPASPRLQFQDPRHASFTPSITPTVQMSVPGQAITTDDPNATSPTTPRFPPEGRSRNAPRSKGHLMSPSETHRARWATRKMTVKSSNNKRASIIGRLANRKSLIGEKKRMSVAESDEHDHDHDDDESVEEDDVASGRSLYFNLPLPDELKDEMGHPAQQFPRNKVRTAKYTPLSFIPKNLYFQFHNVANIFFLFMVILVFFPIFGGENPGLNAAPLIFIVAVTAIKDAVEDSRRTSLDSELNNAPVHRLRHWENVNVEEDNVSLWRRIKKATSRISIGAWRFIKSIWSKKARTERKALKEAAIEEACKSVDFRQSMDSHHRASQGGIPLTPVASPIAPTADAEERARQRAQIVRTMKTDIVNHNAEASGRARFHKDTWKSIRVGDFVRIYNNDELPADVIILSTSEKDGACYVETKNLDGETNLKFRQALHCGRDMRHARDCERAQFWIQSEEPHANLYKFNGALKWYQDVPGDDTGEPELMTESITIDHMLLRGCTLRNTEWVMGVVVYTGHDTKIMMNAGITPSKRPRIARELNFNVACNFLILLFMCLICGIASGVFWAKTDSSAHFFDFGMIGDTPELSGFITFWAALILFQNLVPISLYITLEIVRLLQAIFIYSDIEMYYEPIDQPCIPKSWNISDDVGQIEYIFSDKTGTLTQNVMEFKKATINGQPYGEAYTEAQAGMQKRLGVDVVAEGERVRAEIVEAKVHALEGLRRIDNNQYLHDEDLTFIAPDFVADLAGESTAEQQAATEHFMLCLALCHTVIAEKVPGNPPKMVFKAQSPDEAALVATARDMGFTVLGTNTEGTILNVMGEERHYPILNTIEFNSTRKRMSSIVRMPDGRIILICKGADSVIYGRLKKGEQQELRQTTAEHLEMFAREGLRTLCIAQRELTESEYINWKREHDEAAASIDNREEKLEAVAELIEQDLTLLGGTAIEDRLQDGVPDTIALLGEAGIKLWVLTGDKVETAINIGFSCNLLNNDMELINLKVDEDPTGRTTDESMIHYLDAELTKNLKLFGLTGGQEDLDAARLNHEAPSATHGIIIDGFTLRFVLHEQLKQKFLLLCKQCKSVLCCRVSPAQKAAVVSMVKNGLDVMTLSIGDGANDVAMIQEADVGVGIAGVEGRQAVMSSDYAIAQFRFLQRLVLVHGRWSYRRLAESISNFFYKNMVWTFSIFWYQIFCDFDITYIFEFSYIIMFNLFFTSLPVGLMGVFDQDVSDKVSLAVPQLYRRGIERLEWTQTKFWIHMVDGVYQSAVVFFIPFLYFKYTHFASESGQNIEDRTRIGAYIAAPAVLTINMYILINTYRWDWIIVLVVVISSLFVFFWTGVYTQFTASGVFFEAAQQVYGQPSFWAIFVIVPIICLFPRFVSKATQKVYFPYDVDIIREQARMGHFDYLEHPKKNAGGLPVQDPTYSFGSSDSSRKGKHVPYGSVDEDQRPIYPPSVMTKTTTHHAHPSQTGSDGTNYTGHQHQRQSLDFGLVSEADAVPTPSPLHQQIVNVQAGSGGGGGPPPAHQNFNSVSGGHHTSRPSIDRTRPSFDRMRASLDRVRPSFEASNDMTTAARLTRIESTQSARIRMAAAMAEQKEMKEMSNMGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKC3</accession>
    <name>A0ABR3YKC3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="5">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PPG1</name>
        <name evidence="7" type="ORF">Cpir12675_006186</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 9">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="5"/>
    <dbReference type="EMBL" id="JAWDJO010000263">
        <property type="protein sequence ID" value="KAL1888405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="6">
        <location>
            <begin position="114"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="321" mass="36277" checksum="87D6C0391C8DCF97" modified="2025-10-08" version="1">MPGLPTSIDLDECIARLYKKELLAESVVEAVCSKTKELLMRESNVVHVKAPITVVGDIHGQFYDLIEIFKIGGYCPDTNYLFLGDYVDRGMFSVETISLLVCLKLRYPNRVHLIRGNHESRGVTQSYGFYTECARKYGSANVWNYFTDMFDYLTLSVVIDNQIFCVHGGLSPSIHSIDQIKVIDRFREIPHEGPMADLVWSDPDAEKDEFSLSPRGAGYTFGGQVVRKFLAVNGMSHILRAHQLCQEGYQVLYEDRLSTVWSAPNYCYRCGNMASVLEVKDNGERFFNVFAAAPENDMHRDLQSVNMGGNKGSEALPDYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YLW9</accession>
    <name>A0ABR3YLW9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005836</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000221">
        <property type="protein sequence ID" value="KAL1889345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1889345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="428" mass="47211" checksum="5F1912BF2B93C445" modified="2025-10-08" version="1">MAIFVDLEEEPSQAPAVHFPNVIQHEIFRDISQLRITLNVEQEQPKPKAQSQSPTNPQDTQASLEELYSALNSEPEVQLPAAIRAFACYPVVIAIASHIDLNTLDSLSRSCRHIHDSLFQFHNALMRSTLHCNKEELRVQGALDHETGPYGFKTNYCARDMVSECRRCGCVVCRNCVIKPPATPALKGRHRRLCLDCTKAPLTSLFVPPMDEKLANREIVNHAMCTCQYEGVWLCKSCGQGNNSADSLYHRLWGWRLQYGEIIGGLGTGIGDGDRGVICGRESRCIGAKEREYEIDCDAEDRRTPSPTIYGSGSGSGSVSGSSSPQLGLSHATMTLDSASAQLQLQVPTARKEPGYSRHQIEGIGGQLRTKLVRMVRVGASVPEWSDERSSRAILAKEIKGETRSWCGWCCRPIPGEKDRAAFGVGQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YMB1</accession>
    <name>A0ABR3YMB1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_006157</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat MET30/SCONB/SCON-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000259">
        <property type="protein sequence ID" value="KAL1888499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050995">
        <property type="entry name" value="WD-F-box_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14604:SF4">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14604">
        <property type="entry name" value="WD40 REPEAT PF20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="6">
        <location>
            <begin position="141"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="367"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="408"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="534"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="574"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="238"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="656"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="256"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="270"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="660"/>
            <end position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1888499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="947" mass="106854" checksum="47686F5AEDE8AB18" modified="2025-10-08" version="1">MNHQFSVGQDQQQQQQQQQQQPDEGFYEQQQHQQQQDHVLQLQQQLQLQLQLQNSLQIQPQSQSQSQRSGPDDKFGLLLLRRGDDDKLAGGDINSLVSLQLQAIQTLPLEIQKKFAMELLQGLPTSSVAEIVYSLSPRLYIDFVQYLPAEVCLKILSFLDVRSVIRFSCACRSWYHLSLDSRLWRQLYHLEGWSISQSELVRLERWANSSQLNSSSIDFQFSSKATHRDHDVEMLDSHTPTSAIAPNGHSAPGGTASASNISTDTVMVEAKAASSSPSSKSASRLTSPVTPARSRGRHEDPDFEYLDRPTVPQSNEIPQLSLWSFNRYNDQFRINWKYIYVMRHRLEKNWSHGRFLNFQFPHPKHPEESHRECVYSLQFSKYHMVSGSRDRTIRIWDMRTRRLVRPPLIGHAGSVLCLQYDSSPEEDVIISGSSDSDVIVWRFSTGEMIQKLTAAHRESVLNLRFNKNVLVTCSKDMTIKVFNRHPLKYGDAGYGPGDPELLSKVPITVKRYGYENGPADYMPIKPPYETVCTLTGHTAPVNSVQIYDKEVVSASGDRLIKIWNWEKGQCVRTVQGHTKGIACVQYDGRRVVSGSSDNEIKIFDSRTGAVVARLSSHRHLVRTVQAGFADLPYSEVEDEREARLVDLEFDRAVAEGLVDDPSRPHQRERNRSMVPGSRRPDQLLSRGAKLPPGGGGGPHARIVSGSYDETIVVWKRNHDEIWQDSLTLRQEEAILNAQMLEAQRHSPHQPLPPRTMSQWQEHCNHILSLGSVDLHATLVKRPALLLLVNIFQGLIDRVSHPDSRQHLRTQLDISLNKYVQAVQVHESRRSTASNSKSAASVSASPATFALDSIMNPARGAASLAAAPGSLPTGNGMPNFEIDPVRGPPVSMRQITHRLDLGTARIFKVQFDATRIIACTQKPTIVGWDFCCDDRELKALERLFLPIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN24</accession>
    <name>A0ABR3YN24_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Glutamate decarboxylase</fullName>
            <ecNumber evidence="3 7">4.1.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_005668</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-glutamate + H(+) = 4-aminobutanoate + CO2</text>
            <dbReference type="Rhea" id="RHEA:17785"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:59888"/>
            <dbReference type="EC" id="4.1.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.15" evidence="3 7"/>
    <dbReference type="EMBL" id="JAWDJO010000206">
        <property type="protein sequence ID" value="KAL1889764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010107">
        <property type="entry name" value="Glutamate_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01788">
        <property type="entry name" value="Glu-decarb-GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43321">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43321:SF6">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="500"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="8"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="514"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1889764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="524" mass="59077" checksum="9B139193833A517B" modified="2025-10-08" version="1">MVHLSKIDTPTSHTPGSGSETGASTPSDSLTKALHKVRLELADNDDSYTTTVYGSRAAGRELPRYEMPEDELPRDIAYRLIKDDLSLDGNPMLNLASFVTTYMEDEAEKLMSEAFSKNFIDYEEYPQTADIHSRCVNMIGRMLQGDSHSVGTSSVGSSEAIMLAVLAMKRRWKNRRIQEGKPYDKPNLIMSSAVQVCWEKAVRYFEVDERYVYCTRDRFVIDPEEAIKLIDENTIGICAIMGTTYTGAYEDVKALNDLLVEDNLETPIHVDAASGGFVAPFVTPDLEWDFRLPRVVSINVSGHKYGLVYPGVGWIIWRSPEYLPQELVFNINYLGAEQSSFTLNFSKGASHIIGQYYQLIRLGKKGYRAIMSNLTRTADYLALSLEALGFVILSESGGSSLPLVAFRLPDQPTDAVKIKSPQGRFYDEFALAHQLRVRGWIVPAYTMAPKTGEMKMLRIVVREDFTRPRCDKLVDDIKLCMELLGQIDQKSLEHMKTFISQQRSSSNTHHHAKHTPDKYKVSTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YN28</accession>
    <name>A0ABR3YN28_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">N-alpha-acetyltransferase, non-catalitic subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MAK10</name>
        <name evidence="6" type="ORF">Cpir12675_005872</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MAK10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000225">
        <property type="protein sequence ID" value="KAL1889226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057983">
        <property type="entry name" value="NAA35-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007244">
        <property type="entry name" value="Naa35_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057982">
        <property type="entry name" value="TPR_NAA35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21373">
        <property type="entry name" value="GLUCOSE REPRESSIBLE PROTEIN MAK10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21373:SF0">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 35, NATC AUXILIARY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04112">
        <property type="entry name" value="Mak10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25789">
        <property type="entry name" value="TPR_NAA35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAA35-like N-terminal" evidence="4">
        <location>
            <begin position="45"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="NAA35-like TPR repeats" evidence="5">
        <location>
            <begin position="323"/>
            <end position="726"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1889226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="748" mass="84454" checksum="384A9FBA053FB097" modified="2025-10-08" version="1">MTFDMATMGSSLPSWMYPSSQAPASGLVYTDVTAAFRRAVADMKPGEIIKDDNFSLFDSVAALEIMDPKMDINCADAQTKPEPEYDLSRDLTPQQVLGIIDQLISQEMAWHTGYPLSLTLFSSHYIDQLLSTVPSKVQTAQFSFKLPWNKFTPVSALRAYCIGLIKTCDMVNDQINQEHYYEEEDFVTNTYKRSLFSHFSVESVTQELIDAHKSLSQGACDINPELTAALCARLHFRASFITALENTQHRLYPSLIEQAWTKALKDVEDVIATRHLGEPVPEAFSAKLQQKLSSSMPPRPIVDIGHELGFRLLKQLFEDGLKVTDVLDYKDPITVQNFVVHFQAKKPTPLVITRTILQRYLFKDLVVLGNASLRLLMDDDLTILVKPPAVLLDPINDYVENSSDVRHRIAQKMEAFRVRAAQCYLDIYRSLCQNRCRVRRTLYHVVRDWDLLEINAIEFDSCLHTLVTQPETFGLSQEPLADWNCTVYTADWQPLTLWSRLHKLKVMLYIVELGFELDVYYKHEMAAMYFYLSTLCEEVQALETSIQNYSAAATAATTTSALDTVLKGQQHESLMQTETLRFTLKHGMASALFSIFTVLQRMNAIEIPKQPCGTDELRYDLRMRPFAIKSRPLQTYTEFQALLTGTSSGSTPPPLEELLDCATSAINKAQTNLAGLQALIGKGTFAHGSLQLQTDHLKKVERATKASAETIKVLRKAIQCDKKVQVTIPVPDDIYAGLWVVPQVKLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YP30</accession>
    <name>A0ABR3YP30_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_005523</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000193">
        <property type="protein sequence ID" value="KAL1890108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="129"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="209"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="340"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="307"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="129"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="242"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1890108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="433" mass="48096" checksum="E82CDE0445A1A0DA" modified="2025-10-08" version="1">MAAVHTKLHRHRSRGNGRLTGKRGSPSDKGSLDMSRTWEDQIHYESHGWGSSSARNNSFDCVDTSATTTTAISSSAIPRETNYNRTGSVDMLDSTFGSPRMHHASGTSIFATPRNNKYPAHNRSVSCTSHTSIATSSSGPRSGTFVHPFQQTPRTSSPPLYITPVSPLDNSHFPHDYSPTIEENVNKLYPPSPSSFAFRSSSVDARNSLEHSPTYHNMRISPTTLTPTYSPTYSDPHTSPTRESLCSPSSTGPLKSLSPTSATQVMSPKRSSLDMTFRLRSRSEVDTFTQREQIREARRKFDEKQRVKEEKYALVELEKKEREATKEAVKFEKAQLKKACSNGSSGRNSHEQAAIRRGTGGSNDTEKVSDLRFAANNYNNITPGVAPTDDIEDAGADVNQSSGRMYSAKKRTQSTWTAFILWVRTRLFKMGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YR30</accession>
    <name>A0ABR3YR30_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005224</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000170">
        <property type="protein sequence ID" value="KAL1890828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1890828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="453" mass="48906" checksum="E4F70B8EE5E59202" modified="2025-10-08" version="1">MAPPATPYQFTCGHPSQQPNQQQKQSQASQKYSQSHGNAPTPRFHAASFIPPGYPNNASYNDQPSSILLTNSTPFRAPDARQFRASQLPELPSVSGSANARRVIEDVVSSSPVDRVPESDLGFGDSEDSEAEARASVGVVRRNRTQLDDLVDDTSQDVDLPVRKKRRVSISEESIASMSFDIRTSLGVAEDLMIDEDEDGPEEAVYSAARGSETLLQAEIFSGSVSGRSSDDGTQRLDLNIGDNGGSDYSRFNTSGVSNSGSLAGSDIDARYPLSNLSTPTRALSASPPPQPTFQRAPRFRTASQSTQSTDPEVVHMLFSPPRPRSTKKGTSVYRPHGLAAAMQGWLAHVRGLMGDEEQLRIVQARVTRRMVIAEAIRENGLHSASAEARVRVMLAGVCEGIAPGRVVAISPPTWWADIDGIEWLVASDWRVLGTVGDEFSVSEELECGAPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRL8</accession>
    <name>A0ABR3YRL8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cpir12675_005332</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000179">
        <property type="protein sequence ID" value="KAL1890579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000778">
        <property type="entry name" value="Cyt_b245_heavy_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF9">
        <property type="entry name" value="FERRIC REDUCTASE TRANSMEMBRANE COMPONENT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00466">
        <property type="entry name" value="GP91PHOX"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="297"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="356"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="382"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="547"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="Ferric oxidoreductase" evidence="10">
        <location>
            <begin position="254"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="Ferric reductase NAD binding" evidence="11">
        <location>
            <begin position="545"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="27"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1890579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="711" mass="78558" checksum="D01C2346EFAE1EE2" modified="2025-10-08" version="1">MTHASGDSLESLHSSVRHRYHKQQPDFPTAVAKSQAPFPSNSRHVSHHSFPPDSAKAQGISEIRITTIPRQNDTGVSIALAGVSMVLPVSIAAYLLTGAANAMGSEAANWPLSFLALTEADKKLRRAILDRYANYTLLATLFLILGIGLARFAARTAWQTQDMVGGNTNSASSHRENYHLLDRPTSPKIERGSLTGWRLRLSRIQWWLRGDITISGQNWGQRDIWVGGALWSVILAFLSVYETQGDYLHLTKRLGVVAVGQMPLQYVLTLKYLNPVAHILGTSHEELNRWHRLLGRIVYGWMALHAVFYTNFFYWAGTMSTKPFTFVVLMGEIAFFAMCALAGSSTLKIRRRSYRLFFLLHVVASMVVPPMVFLHADNAGLVRIHCIISIAILILDIIIRRIFTIKAMCTITTISDNSLVKIVAEVGAKARYFSQSPASHVYLNIPIGARDIKAPIMSPKNLQYESIFNPFTVAATDVSSGEITLIARIMNGPLTQRLASLAAPPLTDSSTQSPALYKTQVPLCFDGPHGAASRSLRRLVSADIDRVLLVAGGVGASFIVPVYRAILTYKPNTQIEFVWAVREVGETQWAISGPQLMLDNLKIKIYVTGDNSDALPVGTRTPLIAASYGSSTGNIAHRNSSASENHSMPVYTRARPNLVRTVDDFFQASPNDRVAIWVCGPEQLAKDLRACVTPWVMDGRHVEWHNEGFGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRM7</accession>
    <name>A0ABR3YRM7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ornithine carbamoyltransferase, mitochondrial</fullName>
            <ecNumber evidence="2">2.1.3.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Ornithine transcarbamylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ARG3</name>
        <name evidence="10" type="ORF">Cpir12675_005343</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.3" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000180">
        <property type="protein sequence ID" value="KAL1890561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004585">
        <property type="term" value="F:ornithine carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="entry name" value="Aspartate/ornithine carbamoyltransferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002292">
        <property type="entry name" value="Orn/put_carbamltrans"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00658">
        <property type="entry name" value="orni_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45753">
        <property type="entry name" value="ORNITHINE CARBAMOYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45753:SF3">
        <property type="entry name" value="ORNITHINE TRANSCARBAMYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00102">
        <property type="entry name" value="OTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="Aspartate/ornithine carbamoyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00097">
        <property type="entry name" value="CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aspartate/ornithine carbamoyltransferase carbamoyl-P binding" evidence="9">
        <location>
            <begin position="31"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="Aspartate/ornithine carbamoyltransferase Asp/Orn-binding" evidence="8">
        <location>
            <begin position="188"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1890561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="353" mass="37379" checksum="55D7C754B4D5CE32" modified="2025-10-08" version="1">MKSHTTKAAQAAISGLQKRAFSASAAPSAPRHLMTIADLTPPEFTTLVRNAAAHKTAVKGGQIPAQLAGSMTGKAVAMMFSKRSTRTRVSTEAAVAMLGGHAMFLGKDDIQLGVNESLYDTSKVISSMTSCMVARVGPHSDVTGLAKDSSVPVINALSDDFHPLQTIADFLTLHETFAPGAASGLGLQGLKVAWIGDSNNVLFDLAIGCVKMGVDIAVASPAGFTIPETMKQLILAAGKGVASPGKLIETNIPEEAVKGADVLVTDTWVSMGQETEAQRRLKAFAGFQITNEMAKRGGANEGWKFMHCLPRHQEEVHDEVFYSDRSLVFPEAENRLWAAVSALEGFVVNKGTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YRU3</accession>
    <name>A0ABR3YRU3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NXF1/2/3/5-like leucine-rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_005263</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000174">
        <property type="protein sequence ID" value="KAL1890705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057125">
        <property type="entry name" value="NXF1/2/3/5-like_LRR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15454">
        <property type="entry name" value="NISCHARIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15454:SF69">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 11-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24048">
        <property type="entry name" value="LRR_NXF1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="NXF1/2/3/5-like leucine-rich repeat" evidence="6">
        <location>
            <begin position="530"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="28"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="288"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="378"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="680"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="837"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="427"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="691"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="719"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="783"/>
            <end position="798"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF24048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1890705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="988" mass="108472" checksum="AA50AE3F2149631A" modified="2025-10-08" version="1">MDSEDGETYIKNLANYVHSNEKALANVNTTPRRGPISRHTPSHSMSSAAAIQRSPTLPARPSTSASSLSFTPGFPLSLGFGSRPCKSTKLSFTPHHLFYLLSRFEELGIDVGPLKIRLENIQDTSNTSNYVSFLSSGQRSKTHGSDIDSIRSVSSIRSVMSSVTTMWSHFGFGGSISAARTERHKAFIHTELKYLYSSFTIIPALRLAPDWRARLVRGYEEFPFDSAVPLHAFKNVQTLDLEDIDFRQFFGWDRMADQLKSLTLRRASIDDPADILIDIVLDDMDGRRRRTAKAQHTPPPTWTGNSGAASSHRRSPTIGGHGDVPRLMSPPASPDPRCSASDMRIGSLNILESAIYDTSFPTNSDSISRQNYRMRSTSVCHPENDDGQSPTRIYHPAAPTTGRSRHDRDPSMNLANQTRVPEKVRRSGSGSSHSSLSDSFHSQVTARPHSHQRRGSASNLLHIASNSSTTVLPATKWRFLRHLSLSDNALTTIPGSSLAPLANTLHSLDLSSNLFTQVPDSLAILTALRALNLAHCMIDSLHSLTRNPLPAILSLNLRANRLQSLSGIEKLLPLERLDLRENRLTDPVELARLTGIPYIREIWVEGNPFIRTHKDYRITIFNLFRKTPGYTEDLVIDGSGPSYSEKRYLLDRVPVPAAVPVVRQPAPEVYLVDIGLGSTSPTPKPTATYEQHCRAQREPTVLRKDRPTPRPVTNDAHRSPHRRKKGSKRRIVDLSTSEPSRLPPPTMLTNDMTPPPIPSEYLRGSQSQKAPVLPSFPQASSQKTPASKASTCATSSKEASQHECRKPEICEAATPATATTFTDAPPAIPSARVATINKPNASRHRHRISQSSDVSQPEPASPPLEAQAQTPKVVPAADSCANTVCSVISPESDMSVLYGSGEPDGSEWDMSGELYRRKIEALRSEVGERYLTMLSETALTEGSLADGRWKASPSVEFAPDYRPAISTVSPLQPASISKPTVVSGRMIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YSF0</accession>
    <name>A0ABR3YSF0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PHO2</name>
        <name evidence="9" type="ORF">Cpir12675_005462</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000188">
        <property type="protein sequence ID" value="KAL1890269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051000">
        <property type="entry name" value="Homeobox_DNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057939">
        <property type="entry name" value="TRF2_HOY1_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24324:SF5">
        <property type="entry name" value="HEMATOPOIETICALLY-EXPRESSED HOMEOBOX PROTEIN HHEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24324">
        <property type="entry name" value="HOMEOBOX PROTEIN HHEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24818">
        <property type="entry name" value="PH_TRF2_HOY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="51"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="53"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
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            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="567"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1890269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="592" mass="64663" checksum="261B6DCCBB0A7AF6" modified="2025-10-08" version="1">MESTSAPMMGPPSMMDSPSPSTPGGSTHNFSQSGPNSASKRPPRKSTLTQQQKNHKRQRATPDQLSTLEMEFNKNPTPTAAVRDRIADEINMTERRAKIKQLAKKSLENGEDMESIPESMRQYLAIQAMETGKGIGGSFLGRSGLYPYGNNMFMHGDQAAQSKVLIQHFTCRALSIGKWTRVGQNTMDLIVFYSPDKCTMTYYINNDQAGYKIEYPFSYIKNIHLENNDDDPTKPSGIVIDLTSPPFFFMDQTAITQGFVNCLDFTEDKQASQCLVHRLAGNAKVLSGQLAKLISLESFINRHAHQHMFDHNNLAVSAPVSPIPRPSSQPNFMAPPHVGMFQETWGISNMQPNMRAGPGHKRQRSRSVPMAVDFSMFQQPMPSFYIQQPGEAASQHSPNLYAPVPQQPANMGSGLRIDTQAGFGLDMRQYPMSATAASPADFSSPNYFAPPTGEPTPLPVSTPYSGSFLSPMANSTTMAPVISPLPFSTSPVTDSAIAGQSPPIGMMRPTSAEVYPGTGPDSSCAISDDGNGFGDMYPKQTMNLPIHTHSPASFVEPPTNDIDMNHLVAYDGSDHNPPSLSPEVRSQMAQVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT28</accession>
    <name>A0ABR3YT28_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000164">
        <property type="protein sequence ID" value="KAL1891013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="90"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="151"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="172"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="599" mass="66349" checksum="A852AC732EA40191" modified="2025-10-08" version="1">MSFSRNEHHSSDNRDQRASNARSRSFYADILLNHLQPDSSFTDSQGLSSLPPPPVLSTPSRQTLSRQMAEFEAFRSQLSDTSSRVGQTSETARDHNYSASRFAGFLSPATAARAARAARSRNSQTALTDGLSSLISQSPLHTRQAEHDSNQPSSATQSSQISQQLTGLPINPEEQPSSSRQPQSQPASFSFIHTPEVLGTVNPHNLFTDESHKTKRRRLDTYCQPSHLYGRYGQVEPGPLQMEIVQDNGSVFMPCASINNILLPDVRSYDFDVTGCNIVLQHQNGTPFSLQKIVIRSPTSRIADIPPVGLLFLSMEKDDVFRRTAAYQIRTSNTSQHRLLAEDITGRQYRSMYEEDEEECDDIPLEFNSSPPKRGSIKILTENEDLSSDNESVGSDEYRVRDFIDINADTSFDSEPGEASVVYTGLSHYHSSSRTGFPPRSPPNRIGTLPFENDDSDIAFPIRRPARFPERNAGIGRLRGSSSNFLNRLINQESTAAMAAETPLRPANSSATGLEAARQASQLATQNAVRAVGGSFMVPQARFVMDKTKCTIEFDPPLAACNILLKIWCPQNISQRIYLQSVEVIGFAGPRYLPSVELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YT99</accession>
    <name>A0ABR3YT99_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_005035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000158">
        <property type="protein sequence ID" value="KAL1891245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1891245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="307" mass="34783" checksum="124D5A45AE078E22" modified="2025-10-08" version="1">MRQLPNFPGSFLGASSNNRTQPTSSSALNRILHPYPQPPVPQYGGPAPNSQPEMVLPNPFIQPQYSYSVPSSFAYNQVSANGGPILFDHRGGPISGPFPNSHIQPSQHQSYSINDQQQQQPMQLTSFQSQQQQQQQQQYQYQQQQQEQQQYQQQQYQYQHQQDPIVPVNNHRKRPRSIDEDVGSSSAAAQSSSAFVMPVATSSGTPLRAPVSAYSVYVNPQSADEDEHMHQTHNEEIGSEDEPHHRRPERRKTGEWQKMTDHRERATRILRDPELLLTHAESRQDSVAGTRLHYTRLAAGYAVESHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTE0</accession>
    <name>A0ABR3YTE0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">U3 small nucleolar ribonucleoprotein protein MPP10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MPP10</name>
        <name evidence="9" type="ORF">Cpir12675_004928</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in nucleolar processing of pre-18S ribosomal RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
            <location evidence="1 7">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the MPP10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000152">
        <property type="protein sequence ID" value="KAL1891556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012173">
        <property type="entry name" value="Mpp10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17039">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17039:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04006">
        <property type="entry name" value="Mpp10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017300">
        <property type="entry name" value="snoRNP_Mpp10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3 7" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="151"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="660"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="152"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="176"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="228"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="258"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="302"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="312"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="337"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="370"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="406"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR017300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1891556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="737" mass="81735" checksum="5F9C47F2DF52ED24" modified="2025-10-08" version="1">MADGSIDSSLTSTSQTLTLPATTANTSAMATTGSSSPYSDFLESLQRDNRHTFLRPTSDIATSSLNFVKLTLDDFASKVSDEQLAFVRELNKKRKRSDGPVAKGEVLKLRKVHVDGLETSQIWQQAHKIISSSLAYSQDVIHELVEKKDIISSSNNGSGSEAEELGSNSDGYSDSNGDDEDEDQSEDDQDGSENEGEYDETEFTGLDDDDNEQKVTEDQDIEQLGGQDSEEGNESEDDGGSYTEDPFGLNDGFFDIDEFNRQSQRLEEQDANGDPYADHVSDEEEIDWSADPMSKPSKSKSKSGDNVKMNDDDSDAEDDEENGPTFGNVDLFAPDGASEDGLSDQEAAEEPDNEFNANNIYFKDYFAPPPKRKSQAGASKPRKQPKKIEDADVDRAMNDVRRDLFDDMSEDSANEDDLSDASAGDPKSRRSAHERKQYKLAEEIRKLEAAAVEKRQWTLSGEAAAVDRPANSLLEEDLDFEYAGKPVPMITPEVTEGIEDMIKRRILAREFDEVIRRRPDTAVADTRRGLVEIDDTKSKKGLAEIYEEEHIKNANPDSYISQSDEKTQREEREVEAMWKSVCAKLDALSSWHYKPKPAEPSLTVVSDVATVAMEDAMPTTAQGVTNDSAIAPQELYKTSGATAAKGELVTRSGLPLARQELSRDERQRMRRRDKERMAKDASDPDARLSKKAKMQKDTIEDLRKGGVKVVNRKGEVVDVDGNKIKADKTMSLGNYKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTE9</accession>
    <name>A0ABR3YTE9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Beta-xylanase</fullName>
            <ecNumber evidence="11">3.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Cpir12675_004875</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the glycosyl hydrolase 10 (cellulase F) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="11"/>
    <dbReference type="EMBL" id="JAWDJO010000149">
        <property type="protein sequence ID" value="KAL1891655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044846">
        <property type="entry name" value="GH10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001000">
        <property type="entry name" value="GH10_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490:SF35">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00331">
        <property type="entry name" value="Glyco_hydro_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00134">
        <property type="entry name" value="GLHYDRLASE10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00633">
        <property type="entry name" value="Glyco_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51760">
        <property type="entry name" value="GH10_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 13" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047054386" description="Beta-xylanase" evidence="13">
        <location>
            <begin position="17"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="GH10" evidence="15">
        <location>
            <begin position="17"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="14">
        <location>
            <begin position="496"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="359"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="370"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="402"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="414"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="442"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="458"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1891655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="532" mass="56180" checksum="8947E22715C0821A" modified="2025-10-08" version="1">MRFTASTLLMASTAMAASNLGGLNQMAKAAGKMYFGTATDNSELTDTAFVEMLKDPEMWGALTPGNTQKWQYTEKTQGVFTFEDGDVIADLAASQNMLLRCHTLVWYSQLPQWVTSGTWTKDTLTKVMETHITNEVEHYKGKCYSWDVVNEALEENGTFRDNVFHKNIGEEYIPLAFQYAAAADSVAKLYYNDYNIETSGAKAKAAVSIVESVKAAGAPIHGVGLQAHLIVGQVSPKASYVETLQSFLDAGVEEVSYTELDIRHSSLPPSDSALAQQGDDYAAVVGACMDVAKCIGVTIWGFTDKHSWVPSTFNGAGDALLFDKELQPKPAYHSVSALLAGASPGGAMTVTASATMSAAQIRAATPTPNPEEETCEADDDIETTPSSSRGAQGPAATSPSTPDDDSCDPEVEDPNTYTPSTPNSQPSNNNPSTPTTPVGTQNEEDTCDPQEEDEPTYGSTPSSAPSSARPSAAASGTTPPSPAQTGSNTGSNTGSGTAGQFQKCGGNDYNGPTACAAGFTCTVQNEYYSQCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YTI8</accession>
    <name>A0ABR3YTI8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">U3 snoRNP protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">UTP20</name>
        <name evidence="4" type="ORF">Cpir12675_005063</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000160">
        <property type="protein sequence ID" value="KAL1891217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052575">
        <property type="entry name" value="SSU_processome_comp_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046523">
        <property type="entry name" value="UTP20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011430">
        <property type="entry name" value="UTP20_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17695">
        <property type="entry name" value="SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17695:SF11">
        <property type="entry name" value="SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20416">
        <property type="entry name" value="UTP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07539">
        <property type="entry name" value="UTP20_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 20 N-terminal" evidence="2">
        <location>
            <begin position="904"/>
            <end position="1511"/>
        </location>
    </feature>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 20" evidence="3">
        <location>
            <begin position="1743"/>
            <end position="1961"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2465"/>
            <end position="2527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2653"/>
            <end position="2699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2466"/>
            <end position="2488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="2490"/>
            <end position="2507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="2516"/>
            <end position="2526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2656"/>
            <end position="2668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="2669"/>
            <end position="2684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="2699" mass="303464" checksum="30C9EE073D1ECFCE" modified="2025-10-08" version="1">MPPPSGRILKKKAKSSTPHQKNHRWESFTSKISKLHSLDPIKKVRRYDLDADDNAAEVSYFSTALHKWSEMNISRSFVSFRREAMPLCETLVQILHFEDRIFGLLSRHISANDKGSLEPLLDLLTSFAHDLGVRFEKYYAQSLALIVGVASQPQDVDVIEWTFGALAFLFKYLSKLIVPDMRPTYDVLSPLLGKTKVSPHIARFAAEALSFLVKKAASPSTRESSLQKLAQHVQKDLYAQRGERQFLLFKDGLMTIFAEACKGNSETVHSNGSAVITSLLRSIPHDEFALIEECIWTDVACGVTTSIIHHSNAAAMAETVTAICEYGNAQIENQKPASVPWRLLPIIRVYGTLMSVRKGSRISDWAPLVKSMIQALETISKTSPTIAISEDEHAPFWNYVMFNIALMWQLAPIDSLITSITPFTNILNRDPFTRWYIQFCSLFAELDSVRFKSLFLNHFQSFIATCYSDLDNEELLCILLPRLHELNVISFPADKEGFSIPQGWQAQIVNKFEKLEIYPFPERGAYDKDPRTWRDKCLPKYASLLHVLESCNVHPSTNARIAELMLRKLKLSLRPTTTLESDEVHFIVSRGFHAYLRMVRGAGSVDSSLQPLLRAALPRFGRSIGFLESMLSYEQHLAAQEPSPEKIERASESPIDVETAVMPLVANLASPSHELRYNSLLLLRVMFKVQGQEIHECVDTMVGIEHTPLELANTRHIGMLMRKLGISFASIEAPWLQKAVASFLFGMLAVKLAPVWDYAIEAIQKVAESKVGEEHVSALAFDWLTVPSPRWTGCATQTTEYGRRYMTDFECTNVDKTRVVSTKVFETVSDAVGKLLAAFDEKQSIVEDYCDQARGRALKAFAAVPLIAESKSRLFIPHFLSWSVNDEEAAKNMSQETDHQVQKSWSLSDRKAMLKVIEQFINPCVLFQHKKVYDALLSLLENGDVDIQRLALKGILTWKQDGVKPYAERLETLLDDSKFKNELTLMFQGEQEIQPGHRAELMPVLLRLLYGRTISKKGIASGRHGLQATRLAVLRNLSVTDLGAFIEISLGALRGVKILDGNGQLKTEIVDQEIIPVRQMFGFLNMASSLTSELGSSVLPYTETLANSVLYCLFFCVRRLRGIAEEDQDVEELEEQASNNSLLRSARTAGLKCLNLLFRNASMFEWTAYAAPMVAELITPRLEKLPIESAQGVSNVLQLVATWSTLPKAAMFMAIDALLLPKMMAILAVEKAKDDVKVFSLRVVRNLVKIVELSAAESEFNELVRTELLETNMNCILEHITIVLEAAASSHELLEACVDTIVEISPYVDARQNVRSVLDISTRLLGQPPRKVNPRTKGKILLVLEKFVAIEGPRLVDSSELSIKIRDALASLFSYFKDHENRDSLCRVLAVLAKHDKSLAESSHLCTELNAYADGLSDEPAYDRRLAAYNAIYSARCVPMTPQQWLPILHNLVFFLKFDEEYGILSSNSADGLRRFVEDVAGVKDPETRLAYEAELGDIVLPAMYSGAREPAETVRRECLRVMGHMLVHIPEWGPISDMEGLRTMEEDASEPVFFFNILSPSTAKQLEAFEILRAANAECEISSANISMFFIPLLEHFIFGRSEGLDPAMGSNATTVLSDLALSLEFRHYRSILLRYIGYIESKPDFQKQNIRLMGRFANSLMVAWKQRLAVSVVSESDVNSAADTDVVLEMETDRTSETKTEAETQKAHTQRLQLTIPEQEKLNGDIINNFLPPMMKHLHEKDESEVSYRVPVGVIVVRLLVILPESEMSSRLAAVLTDICHILRSKAWESREMARDTLVKIAVVLGAKYFGFILNELKGALQRGYQLHVLSYTMHSLLLATIPEFGQGSLDYCLSTMVTIIMDDIFGVIGQEKDADGYTTTMKEIKSSKSQDSMELISKSASITHLSDLVAPMQQMLLQKVDLKIVRKIDALLARISAGLIQNPAAESRDSLIFCYEVIKEVYGSQKAKKQPKIDPKLRRYLIVKGAKKSDRAATSRHTYKLTRFAIDLLRAVTKRFDSLRNSTNLVGFIPILGDSIVDGEEEVKIAVFKLLVTISKVPFSTPNAAGVYKVAVKEAAKTISQSHSTTTDAAQAALKFLSIVLRDRPDIEVRPAAIDVLAEKLKDDLTNTLYRHVTFNFLRAVLDRKIETAAVYDTLDYVGTIMIANEDKDTRDLARGAFFQFLRDYPQKKARWTKQMNFIVSNLQYEREGGRISVMEIMHLLLQKSADDFVQEVAGTCFLPLVMVVANDDSEKCRLAAVELVKQIFRRANTEGTSAFLRLIRNWASSVENRSVFSLALKTMGLYFDAAPTASENKKDLKLVLKLIVDNLPSDATSEASDADLPNVVIDVVRILTTRIPQTLLSPACASLWDGISRWMVHPEHSVKLNATRLISTYLIDFAENRRADSDVLNGSYGLQLGKEDIEQFARLAMRILTTREMEEELASEAGQMLIFLGQHLAQVDGAHTRAEEEEGYEGRGGAEEKGDAAEQIEEDIDTAEPEPETEPEPTVTAAQLEEEPEDENDSLDTKSFNLLFLFKKLSFVLRRGTAPRPLAMYPKVAAMEVLETLCRRVAPAALPEYLKTVMLPLHHLTDPNIAAPFSIDEVFKAKHEGVRTRAQILMDLLKKRVGISEYTRTLLEVRAEVRARRLQRQAKRKIEAVSMPEKHGRDKRKKFERKKVKRQQRGQDHKTMRQSYKGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YU03</accession>
    <name>A0ABR3YU03_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NADH:ubiquinone oxidoreductase 24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">NUO24</name>
        <name evidence="8" type="ORF">Cpir12675_005012</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 24 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000157">
        <property type="protein sequence ID" value="KAL1891328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03064">
        <property type="entry name" value="TRX_Fd_NuoE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1590">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002023">
        <property type="entry name" value="NuoE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042128">
        <property type="entry name" value="NuoE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041921">
        <property type="entry name" value="NuoE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01958">
        <property type="entry name" value="nuoE_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10371:SF3">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10371">
        <property type="entry name" value="NADH DEHYDROGENASE UBIQUINONE FLAVOPROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01257">
        <property type="entry name" value="2Fe-2S_thioredx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000216">
        <property type="entry name" value="NADH_DH_24kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01099">
        <property type="entry name" value="COMPLEX1_24K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="212"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1891328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="255" mass="27799" checksum="74C232961FB2F517" modified="2025-10-08" version="1">MASKLLSLARFSVRPSGIIRPRASATTVAVSRASHTLSVHRNTPENNPDVPFKFSPENEKVIAEILKKYPPQYKKAAVMPILDLGQRQAGFTSISVMNEVARLLDMPPSRVYEVASFYTMYNRTPVGKFFVQACTTTPCKLGGCGSDKIVKAIKDHLGIDQGEITADGLFSFIEVECLGACVNAPMVQINDEYYEDLTPETMVKVLDGLKETVTSPNAKPPKPGPQTGRKTCENAAGPTSLTSKLWSTETTRADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUQ6</accession>
    <name>A0ABR3YUQ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Alanine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Alanyl-tRNA synthetase</fullName>
            <shortName evidence="9">AlaRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 13" type="primary">ALA1</name>
        <name evidence="13" type="ORF">Cpir12675_004843</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Ala) + L-alanine + ATP = L-alanyl-tRNA(Ala) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:12540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:9923"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78497"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="9">Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.7" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000147">
        <property type="protein sequence ID" value="KAL1891770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00673">
        <property type="entry name" value="AlaRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.980.10">
        <property type="entry name" value="Threonyl-trna Synthetase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00036_B">
        <property type="entry name" value="Ala_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002318">
        <property type="entry name" value="Ala-tRNA-lgiase_IIc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018162">
        <property type="entry name" value="Ala-tRNA-ligase_IIc_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050058">
        <property type="entry name" value="Ala-tRNA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059090">
        <property type="entry name" value="ALA1_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023033">
        <property type="entry name" value="Ala_tRNA_ligase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00344">
        <property type="entry name" value="alaS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11777:SF9">
        <property type="entry name" value="ALANINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11777">
        <property type="entry name" value="ALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26023">
        <property type="entry name" value="ALA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00980">
        <property type="entry name" value="TRNASYNTHALA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101353">
        <property type="entry name" value="Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="ThrRS/AlaRS common domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 9" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alanyl-transfer RNA synthetases family profile" evidence="12">
        <location>
            <begin position="6"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="921"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="807"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="604"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="608"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="723"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="727"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1891770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="959" mass="106873" checksum="2313D799DF8F1C0B" modified="2025-10-08" version="1">MAEIQWSGAKVRETFLKYFEDRGHTIVPSSSVVPHDDPTLLFTNAGMNQFKPIFLGTINKGNELASLKRAVDSQKCIRAGGKHNDLDDVGKDSYHHTFFEMLGNWSFGDYFKKEAIHMSWELLTKVFGLDPNRLYVTYFEGDPELNLEPDLEAKQLWLDVGVPEDQILPGNMKDNFWEMGDQGPCGPCSEIHYDKIGGRNAASLVNMDDPMVVEVWNNVFIQYDRQKDRSLKPLPAKHIDTGMGFERLVSALQNTVSNYATDIFTPLFDQIQKITNARPYTDKYGKDDADGIDTAYRVIADHIRLLSFSITDGAVPNNDGRGYVVRRVLRRGARYARKYFNAEIGSFFSQVLPALVEQMGYQFPELAKKKAEIKEILDEEEVAFARTLDRGEIQFEKFVNDTIKKGEKKLSGEVVWRLYDTYGFPLDLTKLMAEERNLDIDEAEVEVAREKAREASKVVKESTQIFSKLDVHQIAELDTLQVPRTDDEPKYLPPNAVAKSKVTGKVQYIYDGKSFAKTTKEIPSGTALGLLLDRTNFYAEAGGQVADSGLIVIDGVATFKVLDVQSFGGYILHNGYLEGGVLSSGDEVICEYDELRRASIRNNHTGTHVLNYALREVLGDEVHQKGSLVDEEKLRFDFSNKTGISVSDLSKIEEMSKQYIKDDKVVYYKDVNLEAAREIEGLRAVFGETYPNPVRVVSIGASVEDLLANPKNPEWRKLSIEFCGGTHVTSTGLIKDLVVVEESGIAKGIRRVIAYTGEAARQAQNAAADFGKRIEVLENMPFGPEKELDAKNTGVALSTLTISAVTKDTLRKRFEKITKEITDQQKKRQKLEAKTALEAVQAHFKKDEGAKVFVGRLPISANIKAISEVINHYKTKDKERSVYIIAGNESSGVAHGVFVGSHLAGKGVTAEAWATTVSEVIGGKSGGKEPSRQGMGTKPESIEEGVATATKWLEEKLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YUW4</accession>
    <name>A0ABR3YUW4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nuclear import receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MTR10</name>
        <name evidence="4" type="ORF">Cpir12675_005093</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000162">
        <property type="protein sequence ID" value="KAL1891124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051345">
        <property type="entry name" value="Importin_beta-like_NTR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057941">
        <property type="entry name" value="TPR_TNPO3_IPO13_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057942">
        <property type="entry name" value="TPR_TNPO3_IPO13_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058537">
        <property type="entry name" value="TPR_TNPO3_IPO13_4th"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363:SF53">
        <property type="entry name" value="MRNA TRANSPORT REGULATOR MTR10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363">
        <property type="entry name" value="TRANSPORTIN 3 AND IMPORTIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24138">
        <property type="entry name" value="TPR_TNPO3_IPO13_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24140">
        <property type="entry name" value="TPR_TNPO3_IPO13_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24139">
        <property type="entry name" value="TPR_TNPO3_IPO13_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0675">Receptor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="3">
        <location>
            <begin position="33"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1891124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="968" mass="108660" checksum="1CD3F9CC95D9E450" modified="2025-10-08" version="1">MASVPSTEVFRAEDVLAAVVTMRGGDVEAKKKAQEFLQNFQKSNGSWATIISILQSSADDEAKLFAVITLRGKITYDLSTQIPQDQVAGLRDQLLLFLAHFASGPKAIRVQLCVSLAVLAIQMTGWKDVLPTVVNALNSSHAAILDFLRVLPEEVTDGRKITLTEEELSLRTTELLSDNSEQVVQLLTNYAQSSPEAAQNPQLLECITAWLKEVPVSRIASSPLLELIFAAVQEETSLVEAADCLCAILRETCEVDDNLEVIKVLFPQLIQLQPLVKKFVEEEDFESYKAITKVFSTAAEAWVVAIAREPQVFGPLVDVVLECASLDKGRDVIEHTFHFWYELKQYLVLEIYMQGRLHLAPVYSKLVTILLHHLQYPTPETGNEQDLFDGDREMEEKFREFRHQMGDTLKDCCEVLGVTECLTKVLDAINVWMQSYASQATANSVPHWQELEAPLFAMRAMGRMVDLDEGVILPQLIPLLVQIPSHEKLRFATIMVLGRYTEWTAAHPEFLEAQFTYIVSSFETDSKEVVRAAAMAIKFFCTDCRDLLGGQVVQLQKFYDQILDKLPEISQNEITEGVASVVAAQPVAEIEKLLALYCDPLFRRLGEKATAATTEEGKLAVADHLNLITFFIQIVVPLVSDGQENPAVKYWQERFHMLSTVLKSFVTCVPICERICKCWRNMVLSYRTAMTPLLPIMANELASAFSTSREGCFLWATGAILREFSEDREHVSPEISNSIYAFFEAQATTFLRVMNELQPRELPDVVEDFFRLLVDALLYYPQRLIPSNLLTPIFQAAIYALTLEQRDPLSSTLHFLLDLISYASNNPATGSGLLPEVAPQLQTIVKDLILTGGNQLVKQVMAGMMLTFPRDCFANGSSVLLDLFRIFPQETAVWLESTIQLLPAGTVTPAEATRLMTKIKERLQSTDPSDNRQVRTILQDFTNSYRRRNVAPRDGLGQLEATRFRFVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YW79</accession>
    <name>A0ABR3YW79_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Histone-lysine N-methyltransferase SET9</fullName>
            <ecNumber evidence="12">2.1.1.372</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Histone-lysine N-methyltransferase set9</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">SET domain protein 9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">set9</name>
        <name evidence="17" type="ORF">Cpir12675_004671</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Histone methyltransferase that trimethylates 'Lys-20' of histone H4 to form H4K20me3.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-lysyl(20)-[histone H4] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(20)-[histone H4] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:64456"/>
            <dbReference type="Rhea" id="RHEA-COMP:15554"/>
            <dbReference type="Rhea" id="RHEA-COMP:15998"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="2.1.1.372"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.372" evidence="12"/>
    <dbReference type="EMBL" id="JAWDJO010000137">
        <property type="protein sequence ID" value="KAL1892162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140999">
        <property type="term" value="F:histone H3K4 trimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10524">
        <property type="entry name" value="SET_Suv4-20-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1700">
        <property type="entry name" value="Histone-lysine N-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041938">
        <property type="entry name" value="Hist-Lys_N-MTase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025783">
        <property type="entry name" value="Set9_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039977">
        <property type="entry name" value="Suv4-20/Set9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12977:SF4">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE KMT5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12977">
        <property type="entry name" value="SUPPRESSOR OF VARIEGATION 4-20-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51567">
        <property type="entry name" value="SAM_MT43_SUVAR420_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 17" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="8 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="16">
        <location>
            <begin position="121"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="323"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="397"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="427"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="545"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="402"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="430"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1892162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="581" mass="63618" checksum="11956D1F7D7CB77A" modified="2025-10-08" version="1">MPPKSAAQSNNNNSKKPVLTLAQISAYDDILTDALIDHAFYWTIVPKNRPSYHPSRGTPEKEISSIITNEIIVKNDLDSAEQQLIETKGLSKFYTSLRTGAEKTNFRAHMRRYMNAYRVDCSWEVNSTNRYTIINHEASITARRFIRRNETIKYLAGIQVVMTPEEEREISVRKKDFSVVVSARSKCASLFMGPARFANHDCAANAKLMTTSQSGIEIVATRNIEVGEEITVTYSASYFGENNCDCLCKTCEENLRNGWAQPAEGAVAGVPSGVKPSIEGSELAAEGYSLRRRRRLCDDISASSASRSSSAALAVTEDIRPKVARGARHRAAVNATPGIAASESPKASTDPTKPSPKRRLSQLETPPVTPAKRAKSESDSESESGSRGATEVVVSLDKRGNTSKQQASNAPLVQSDARLLSPESMPEIEAGSASAPAAPKTSAKPKSAVRPTKRSPCRVPGDYTLTPLLLCEPEMAWIACTICSVVFVQHNAYYTKSACPRCERHSKLYGFVWPKTEPAGPRDREERVLDHRTVHRFLRAADELRARGRKVQPSRSRSCTAPGEGEEVGADTETGPRQRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YWX1</accession>
    <name>A0ABR3YWX1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="13">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">DRS2</name>
        <name evidence="17" type="ORF">Cpir12675_004555</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11 13">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Membrane</location>
            <topology evidence="1 13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="13"/>
    <dbReference type="EMBL" id="JAWDJO010000132">
        <property type="protein sequence ID" value="KAL1892402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02073">
        <property type="entry name" value="P-type_ATPase_APLT_Dnf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF150">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 13" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="529"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="585"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1098"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1137"/>
            <end position="1159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1180"/>
            <end position="1202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1214"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1245"/>
            <end position="1267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1279"/>
            <end position="1303"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="15">
        <location>
            <begin position="268"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="16">
        <location>
            <begin position="1066"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="210"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1385"/>
            <end position="1410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="50"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="1385"/>
            <end position="1397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="1398"/>
            <end position="1410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF16209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1892402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1410" mass="157045" checksum="7366BC34133A9D86" modified="2025-10-08" version="1">MDGTPPGGLPGRGPSRNQAHQQDLLLDLESDQPAYSNAQRSPLNDDDLMQSYNATHSNAPYPQTQAPRPQPSSERQQHQQQPPPQIQIHDQSDRPSESYDSFVGGRPLAYPPSSNMSSSGLPVSSVSPVSSYHSMNRDRAVSNSGLGDYRPYADEDDAASMYRAETTSYYQNDASDMADTRATAHQRNSVLTLGGGLVGKMKNALGMGQGYSEMDLPLTTPRGGPPTGGLPPGPASSEPKKKRFDLGSFKFGFGRSKVDPATLGPRIININNPPANAGAKYISNHVSTSKYNVATFLPKFLYEQFSKFANVFFLFTAILQQIPNLSPTNRYTTIAPLAIVLFVSGVREFVEDYRRKAADNVLNNSKTKILKGSEFVDSKWIDVVIGDVVRVQSEESFPADLVLLASSEPEGLCYIETANLDGETNLKIKQALPETSVIVSPHELSRLGGHVKSEHPNSSLYTYEATITIQQGGTDRELSLNPEQLLLRGATLRNTPWIYGIVVFTGHETKLMRNATAAPIKRTKVEKQLNVLVLALVGILMVLSIFSTAGDLIQRNVMGSGLAYLDLSPTNTVGKVIEMIFKDLVTYWVLFSALVPISLFVTVDMVKMYQGSLINDDLDMYYEKTDTPANCRTSSLVEELGMVEYVFSDKTGTLTCNIMEFKQLTVAGIQYADEVPEDRRATVEDGVEVGIHDFKRLRQNLQSHESAGAIDQFLLLLATCHTVIPERDEKDNIKYQAASPDEGALVQGALELGYRFVARKPRAVIVEANGQEQEYELLAVCEFNSTRKRMSTIYRCPDGKIRLYCKGADTVILERLNDNNPHVDITLHHLEEYATEGLRTLCLAVREIPEQEFAEWLQVFEAASTTVGGNRAEELDKAAEIIEKGLTLLGATAIEDKLQDGVPETIHTLQEAGIKVWVLTGDRQETAINIGMSCKLLSEDMMLLIVNEVSAEATRDNLEKKLEAIRTQGDGNIESETMALIIDGKSLTYALEKDMEKLFLDLAVLCKAVICCRVSPLQKALVVKLVKRYQKESILLAIGDGANDVSMIQAAHIGVGISGMEGLQAARSADVAIAQFRYLKKLLLVHGAWSYQRIAKTILFSFYKNIALYMTQFWFTFRNVFSGQVIFESWTLSFYNVFFTVLPPLAIGICDQFISARLLDRYPQLYGMGQRNDAFKMKIFCQWIGNAIYHSLLLYLFAELIWFRDLIVENGHMAGHWVWGSALYGATLLTVLGKAALITSNWTKYHVLAIPGSMAFWFLFIAVYGTLAPEMDVSPEYHGVIPVLFSTPVFWLQMVGLAALCLMRDFAWKFAKRMYRPQVYHHIQEIQKYNIQDYRPRMEQFQKAIRKVRQVQRMRKQRGYAFSQADESQTRVIQAYDTTQTRGRYGEMTSSRNTAPTGGSGGGSGRAGYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YXX7</accession>
    <name>A0ABR3YXX7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ML-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_004222</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transient receptor potential (TRP) ion channel family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000114">
        <property type="protein sequence ID" value="KAL1893244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010308">
        <property type="entry name" value="TRP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040241">
        <property type="entry name" value="TRP_Flc/Pkd2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032800">
        <property type="entry name" value="TRP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_7G01610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145:SF6">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_7G01610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06011">
        <property type="entry name" value="TRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14558">
        <property type="entry name" value="TRP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01320">
        <property type="entry name" value="TRP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="322"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="438"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="468"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="500"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="ML-like" evidence="9">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="581"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="656"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="799"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="921"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1023"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="596"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="678"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="799"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="861"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="951"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="964"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1023"/>
            <end position="1034"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1893244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1042" mass="113020" checksum="DC4202FBDF511796" modified="2025-10-08" version="1">MTVYGNVSGSSNPAESLPAWDDSMWQDDSWTTGKIVNRYNNGNITNLKTNINVLNYRPYRNASSFCSRLETGSCPLGPVFNALDSSFPRNLPSFTMSESFNSSFSLTTLSTTFLIIYGQGTGGTGTQIGCVSVNATPDMGSIGNVFIIVPLITLIFVASVNIIAAMFCPWGTTDIFKWSSNHSREITDLLRLVTPGFADCLQYFQFAVLTSSLSLDFPGFYRPIVSRVSWSSLLFDTSFVSSKPTWDALIDGLYVTNSTHGLGNVGQLIGLPTENDLWPCMMVWLLVIIACVLLLSQLGFLVRRMYRFVANIPKEDLRKKNLPFSLGNVVRIVFNFFLLPFVTLSVFQISVGGSAPTSLPIMASLSLIVLLGAIAWIGWVILRTVPRSDLFDQLPTLLLYGPVYNTYTDHGPPFALVPICLTLLRGIAIGGAQNSGVAQISILALCEGLMLVAIITYQPYDRETSMNLYMGIFAFVRLIVILLMVAFAPTLGITEGSRGWVGYAILVIHGCVIIFGFFLNALQTLTEVLARMLGAGGHTTGGLSKIFGPRQLSRRMTHRAHGAASKQSHLSQTAMLEADPNRPGYYMPSGHARNGSAGSLTGINRHTRSSSGFDFEELAYPIGTRNLDSTTSSTGPNTPAEVTSFSFLQSNPSRPAAVAVSAASDPYYRPPRTRREATSSMPPSTTQGASAKDTRRVSVAVPNDTDLEADRDRSGTPAPYAIDLAPRADYSTREVDLYYGLRGPALNSERPGRRLGTGPADPTGPVATAIGWMRTLVMGKTKEKGKGFEVVRSHRMLPEMRDELERDPPPEGVPVATAMSRKGPIESDDDDDPKPRDWTISASALAHHRSGSKTNVGESSRGGDYHPGSRVDDEAAVDGESAPLETGTRSPPRRPFSPASHIIKRIPSPVSSISSGFVSRDISIDGDDESSGIPMRSHPHISTTPMPFLRSTSETSTTTASGTRHPSITSTVILDGSSNQGSMRSEHRSNPSFGQVHQYNVVMDDVRRSSPTRDPLDVDAEAQQAQLDNGSLTRRASGPYWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YYK2</accession>
    <name>A0ABR3YYK2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">E3 ubiquitin-protein ligase</fullName>
            <ecNumber evidence="10">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">UBR1</name>
        <name evidence="12" type="ORF">Cpir12675_004078</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 10">Belongs to the E3 ubiquitin-protein ligase UBR1-like family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="10"/>
    <dbReference type="EMBL" id="JAWDJO010000108">
        <property type="protein sequence ID" value="KAL1893470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16482">
        <property type="entry name" value="RING-H2_UBR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19673">
        <property type="entry name" value="UBR-box_UBR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003769">
        <property type="entry name" value="ClpS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044046">
        <property type="entry name" value="E3_ligase_UBR-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_bL12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039164">
        <property type="entry name" value="UBR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055194">
        <property type="entry name" value="UBR1-like_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003126">
        <property type="entry name" value="Znf_UBR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21497:SF24">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21497">
        <property type="entry name" value="UBIQUITIN LIGASE E3 ALPHA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02617">
        <property type="entry name" value="ClpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18995">
        <property type="entry name" value="PRT6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22960">
        <property type="entry name" value="WHD_UBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02207">
        <property type="entry name" value="zf-UBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00396">
        <property type="entry name" value="ZnF_UBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51157">
        <property type="entry name" value="ZF_UBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7 10" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBR-type" evidence="11">
        <location>
            <begin position="90"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="UBR-type" evidence="9">
        <location>
            <begin position="90"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1893470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="2213" mass="249346" checksum="19E5316D3E919AF7" modified="2025-10-08" version="1">MASSDPPSFAALSTQERQLCEYFRDLPKKFKYKYTQESALELCQMLFWSLAGKDEHLPLLFPKGMPADMKLRGAQGAEEGAEYSEAARGKRCGHILKSGEASYMCRTCSIDDTCCLCSRCYHATDHTGHQVRINISSGNTGCCDCGDEEAWKVPLICTIHSHVHGNDSVDKGKGVDALPNDLKTSMRMTIGRVLDYICDVISCSPEQLRMAKTKESILADETQATLFSNYYGDERPEDERQYCLVVWNDEKHTLRDVQEQIARACKKRQIEAHAHARETDSIGRSILATSSDIEALLRMAKKLEEIRVTVTIRAARDTFREQMCATMVEWLLDVSGCSVGKDHHILLNTICEEFLKPWREGSSASYKLAGLNGIDDEADIEVQIERSQHLSHSLLHAFQQRFAGATAPNLDDDDLDSDGLEIIELQVDDHDNALTDDEDDEDDIMQEIDEDEDDDAVDWVPNVQTVAETEDVVAAGFPPPPPVPPIDPHNNIAAGPSTEATEAGASNAPLPATVAQIPTIVASSVSLTSDSVPSARVRPRDLTPSEADIVEPLIAPNAYPKAEIIPKTPNRRKSEKPKPGRYWTEYPEMYRNPSTEESRADDVFQRVRLDHLILFDLHMWKKVRNDLRALYISTMVTIPKFKHILGRRFAALYTTLAQLYLIGDREPDHSIISLSLQMFTTPSITAELVERANFLTNLFAILYTFLTTRQVSHPWEVSSTATLAFDSGSVTNRRMYHFYMDLKHLFSSLHVQHCLRTEPRYLMQFLDLVKLHQGIGPNTRAVGEHVEYETDSWITASLVTREINRMARQFSEAFRNLAPEDMGSLKNAIRTTAKTLILHCVGAERFRFKNAEIKREVRFKGVGKYEFDIAMEETSVVDFVVEQEPISFHHALHYTLSWLIECGRSMSNEELRNLLSFTTEDLMLQPRSMGHKTMTHSNLTPEDYLINTFDFPLRVCAWLSQIKTNMWVRNGISLRHQAATYRGVSMRDVCYQRDLFMLQTAAVTCNPSRVLASIVDRFGQEKWLAGLFHQNCESQDDNQHLDVVEDMIHLLISILSDRSALIPIEEEPNPILVSMRRDLIHVLCLKPLSFSEISSKVPDRYSEHPDFHSVLEQLSTFEFREGISDVGTFKLRPELAEEIDIFNSHFTRNQREESEAVYRKAMAQRTGKKLEEIVYEPKLRPINSGAFKDLAALTSTGMFAQIVFFCLLYPLNIATSKSTVQPSRVEVYLNSVLHLVLIAIAEDKIDETNCDNEECTSFIEIALTQESITIATDEKNTIRAATIVGLLRLLLLKSEYSGCHGKIELILTKIALQRPSLNKEAHDKLGIAIDSTPEATEDTALSAEEERERKKRAAISRQARVMAQFQKQQQEFMGKQGEIDWGSDIGDSMDEDEEDTKADGTHQVTWKFPSGTCLQCQEKTDERKTFGTFAMFNESRIVRLTDIQIPAVVREVRNTPESLDRQMPRDRPFGMSGENIVKITKYDKDGQSLESEEQGISQGFSSKFTLPGPVSVSCGHLMHFNCFETYYEATQRRHAHQIARHHPESLKRFEFVCPLCKALANTFVPIVWKPKEEVYPGVLQPETKMSAFLNKQMLNPFYTNSQPELKVSTIFSNYASASLIGPLAGSAADARSGSSQWQPVSITSVSGIPGVIGLDLAAQIPQPSNIRESSFPSTNNPMTDLVRIYSRMSNSFRTQDFLPCDMGSDSRQLCFNDTLVRSIAFSIASVEIQQRGVGVVAEPNTAASFVSPGIFVDRIPEISMTYLKILSDTARTYILVGDLRSGTDNFIEAQFQRDACTQLKQLFICDYSDLEDVNNIPPVLAIDGFVLLTDFAYCMSEVHQFEIAHLVRLCYLAEVVRVVHRISNNIPAPSWSRRLFAVPENTSSNIRTFAQFCQRLMEMTFDAKAPIDTTSESESSLENLGFEQAGLSDLAGIYEFVKKYALVFLRKTAILMHARFGVNFSAYTPSNPTADELTRLTEALCLPSFDDIIVSILPDATSLGWPDGLDHLVFGWIRHDLMYPTKSDTKLHKVTVNKLGAVEKSRAFVPMGLAHPAIFELIGLPKTFDTLIEEATHHKCPTTGKDIQDATICLLCGEIFCGQSMCCLREANFELEGKISVGGTQQHMWKCQGITGVFLNIRKCCTFYLFRRSGSFAHAPYIDRYGETDMGLRHGRQLNLSQKRYDILRMAYLSNGIPSFISRRLESDVNNGGWESI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ49</accession>
    <name>A0ABR3YZ49_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_004036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000106">
        <property type="protein sequence ID" value="KAL1893648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1893648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="175" mass="17968" checksum="8EE4D773A3AC1D77" modified="2025-10-08" version="1">MNLSGLHAPPLEPLTPQVSAALFGPAIHHQSPLFGHLPMAEQQGPGRAYDGSDLSDTSSANMDAPLSHEVRDRDSTGDGPKTNISTSSVTEWAALNVDVAQPAHTVAGPSGRATDGASKEACGETERDQGSLKTETVRLSHRSSKPSTGENLAGAGTAASSVSLIIALTALICTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ82</accession>
    <name>A0ABR3YZ82_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_004205</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000114">
        <property type="protein sequence ID" value="KAL1893227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="223"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1893227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="363" mass="38759" checksum="444D33C8F8A7C6E9" modified="2025-10-08" version="1">MASAIAPATSQKAVSSISGLSTMPVSEFLETTSATTFESAFPSVSATISAILSETANTPDVSHNQSPAGIKVSIITGTFAGIALLVAGAWYILWYRGRDGSNWSPRDHNAGNGLAPLSSGISRPVTQTSGGVISTRLTSLPPKNQLTRRQPAVSSADLPKTSAPALCLLFPLPAGTISSPAPTVSPAGPLGARPADLPDSRRNNLSDLSSATPPFNIHQSTALPLHNPLPHHTLSSLKPKPPILNQRPGSPSNSQHEHQALKQEQTQSSNGISVQLERSYSNDPVKNLTAKEFAARILVRDVILNAGIRQLELGDCTLDEFKLFNSELNQADQLQESQRPDKKQQESQKHKSKKDDQQQGRQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZ95</accession>
    <name>A0ABR3YZ95_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Zinc resistance conferring protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ZRC1</name>
        <name evidence="12" type="ORF">Cpir12675_004173</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000112">
        <property type="protein sequence ID" value="KAL1893390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45820">
        <property type="entry name" value="FI23527P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45820:SF4">
        <property type="entry name" value="ZINC TRANSPORTER 63C, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="320"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="10">
        <location>
            <begin position="10"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="10">
        <location>
            <begin position="306"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="11">
        <location>
            <begin position="384"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="139"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="232"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="520"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="144"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="237"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="274"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="522"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1893390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="549" mass="59948" checksum="03FB54DA3FDF3E2B" modified="2025-10-08" version="1">MAWSKETRIITMLAIDIVFFAVELTSGFMLHSLALMADAFHMLNDIISLFIGLWAVRAAQKASDDKYSYGYLRAEILGAFFNAVFLIALCVSIVLEALGRLIEPSEISNPQVMLIVGSFGLASNLVGFLVLGSHGHSHGPGNGYDHDHDHDHEHAPGEAHSHNDPHNSSHDHAHDHSHSHSDATRSAEEGTAGYGATSRSHIHNHKRLTSIEDLSIHPASFRHDILTVSRKIEEPLETSSTDSDNDATATESQPTESTSLLRPGVAVSTDISSHKHTHTHTRSRRDSEIIHSAHNHNKPRSATSSHSHSHNHDDMGMNAMVLHVLGDALGNVGVIVTALVIWLTEWRYKLLADPLVSLFITAIILYSALPLTYATSKVLLQATPDHLNVNEIREDIETLPGVVSCHHIHIWQLSDTKVVASMHMQVAFPMSEAGGEKYMELARRARKCLHAYGIHSATIQPEYCLDPEHAADHEQLAREIHAQGGSSNYDGLGLSSPPQRGDVCLLECVDNCVGKGCCPSPSAQQSPVLSRSSSLSGQSRGRGHSDHQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YZE1</accession>
    <name>A0ABR3YZE1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_004274</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000117">
        <property type="protein sequence ID" value="KAL1893083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.20">
        <property type="entry name" value="Alba-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036882">
        <property type="entry name" value="Alba-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014612">
        <property type="entry name" value="Pop7/Rpp20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020241">
        <property type="entry name" value="RNase_P/MRP_Pop7_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28256">
        <property type="entry name" value="RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28256:SF1">
        <property type="entry name" value="RIBONUCLEASES P_MRP PROTEIN SUBUNIT POP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12328">
        <property type="entry name" value="Rpp20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1893083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="162" mass="17889" checksum="720CDAB7FD951353" modified="2025-10-08" version="1">MHSSARHTKLLRLEKDTKVHKRPLVRQQQSSSRKTKIIYVSGKTPFMSVISRVRKELDKPCGSNRLTSKNMGLSAKISALKQAGGTQGDSKVVTVMGTGKAIEKTLSVASWFSQQNDCEVAVETKTISTIDDVVLKEDNDGLGDEETRRRNLSCLVVSVTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z056</accession>
    <name>A0ABR3Z056_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="3 6">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">FPR2</name>
        <name evidence="10" type="ORF">Cpir12675_003988</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="3 6"/>
    <dbReference type="EMBL" id="JAWDJO010000104">
        <property type="protein sequence ID" value="KAL1893690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044609">
        <property type="entry name" value="FKBP2/11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45779">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45779:SF7">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0697">Rotamase</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045831496" description="peptidylprolyl isomerase" evidence="8">
        <location>
            <begin position="17"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="9">
        <location>
            <begin position="36"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="128"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1893690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="191" mass="20171" checksum="A418EB8F77777DF4" modified="2025-10-08" version="1">MKTIAFLAAFAALATASDLEIVANEEYECDRPTVAGDMIQVHYTGSLEDGTKFDSSLDRGSPLSFKVGTGQVIKGWDNGLLNMCIGDKRTLTIPPSLGYGNRGVGPIPAGSTLIFTTELMGIKGVTNPESLVPKAKSTETPAVEEEQKVSEDKAEDRVEDKADESATSTEAPATKTAAPDASTDGKDKEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1F0</accession>
    <name>A0ABR3Z1F0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial</fullName>
            <ecNumber evidence="11">1.14.15.45</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">2-methoxy-6-polyprenolphenol 4-hydroxylase</fullName>
            <ecNumber evidence="11">1.14.15.46</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 13" type="primary">COQ6</name>
        <name evidence="13" type="ORF">Cpir12675_003672</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">FAD-dependent monooxygenase required for two non-consecutive steps during ubiquinone biosynthesis. Required for the C5-ring hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 4-hydroxy-3-(all-trans-polyprenyl)benzoic acid to 3,4-dihydroxy-5-(all-trans-polyprenyl)benzoic acid. Also acts downstream of coq4, for the C1-hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 2-methoxy-6-(all-trans-polyprenyl)phenol to 2-methoxy-6-(all-trans-polyprenyl)benzene-1,4-diol. The electrons required for the hydroxylation reaction are funneled indirectly to coq6 from NADPH via a ferredoxin/ferredoxin reductase system.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 2-methoxy-6-(all-trans-polyprenyl)phenol + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = a 2-methoxy-6-(all-trans-polyprenyl)benzene-1,4-diol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O</text>
            <dbReference type="Rhea" id="RHEA:81183"/>
            <dbReference type="Rhea" id="RHEA-COMP:9551"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10858"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:62731"/>
            <dbReference type="ChEBI" id="CHEBI:84166"/>
            <dbReference type="EC" id="1.14.15.46"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 4-hydroxy-3-(all-trans-polyprenyl)benzoate + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = a 3,4-dihydroxy-5-(all-trans-polyprenyl)benzoate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O</text>
            <dbReference type="Rhea" id="RHEA:81195"/>
            <dbReference type="Rhea" id="RHEA-COMP:9514"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10930"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:64694"/>
            <dbReference type="ChEBI" id="CHEBI:78396"/>
            <dbReference type="EC" id="1.14.15.45"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="11">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Mitochondrion inner membrane</location>
            <topology evidence="11">Peripheral membrane protein</topology>
            <orientation evidence="11">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the UbiH/COQ6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.15.45" evidence="11"/>
    <dbReference type="EC" id="1.14.15.46" evidence="11"/>
    <dbReference type="EMBL" id="JAWDJO010000091">
        <property type="protein sequence ID" value="KAL1894443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03193">
        <property type="entry name" value="COQ6_monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018168">
        <property type="entry name" value="Ubi_Hdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010971">
        <property type="entry name" value="UbiH/COQ6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051205">
        <property type="entry name" value="UbiH/COQ6_monooxygenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000689">
        <property type="entry name" value="UbQ_mOase_COQ6"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01988">
        <property type="entry name" value="Ubi-OHases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43876">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43876:SF7">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01304">
        <property type="entry name" value="UBIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0274">FAD</keyword>
    <keyword evidence="3 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8 11 13" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0830">Ubiquinone</keyword>
    <keyword evidence="4 11" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="domain" description="FAD-binding" evidence="12">
        <location>
            <begin position="41"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1894443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="494" mass="53738" checksum="850A86A3D11FB7A7" modified="2025-10-08" version="1">MSRPLLAVPSCCSYLQTCTRYLNRQYNVATASTKLNEPDIYDVVCVGGGPAGLSLLAALRANSTTAGLRVALVEAQDLSKLRSWSMPLDKFSNRCSSLTPTSAEFLDQIGAWSHLKRERVQEYQEMQVWDGVSDARIEFDWDGSHSPTGDQTIAFMTENLNLTQGLISRIGQLGQVSVFDGAKVAGIAYGEKTNDHDLSQWPVVNLSSGQRLWARLLVGADGANSPVRTFANIETRGWDYERHGVVATLELEGDGWGGADRKTAYQRFLPSGPMAMLPLPGRLATLVWSTTPERAAFLKSLSPPDFVALVNAGFRLRPVDIDFMHTLTTPDAQQGELEWRLQHTPFDRLAVPQTVTAVQEGTVASFPLKLRHADTYIAERIALIGDAAHSVHPLAGQGLNQGQGDVQSLVRAIESAVLHGQDIGSILSLEPYNAERYAANHVLMGICDKLHKLYSFGSGPIVPLRSAGLAAVNALRPLKNFFMEKASGSGAKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z1S2</accession>
    <name>A0ABR3Z1S2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_003789</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000095">
        <property type="protein sequence ID" value="KAL1894147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF81">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="387"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="422"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="44"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="124"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="165"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="223"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="475"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="530"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="558"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1894147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="567" mass="61445" checksum="B2F6F80A545D556A" modified="2025-10-08" version="1">MGLHSPISTYRQSVSSDTPSELISPTLSTYSSRRSSEKSKFQGYPSPYSSSPPETMNSSAYSYSSSSSSSSSHSHPAYMSKQGEQHRSQSPRALAPPAAYQSHSVHQAGPQQQAARPQLPPISSFFSHVSFSRPESTAPSFAGPPSPEQRHQQHQSQQRPHHRPPATPSTSAPPPPYYRSHGSHGGMSINTTVPASNGRPSSSHVSPMSANVPEPYRYDNANSTSSSGRSYSSTSSSSRPDYLLSRDSPPQARHQQVQSHSHSRPPLQYSSTEPRHSISAVSVSSQTSASAVASSVQSSADGISTVSPADASSAASSSFSQEGLGPKIWTGTHFLPRFIKAAQVPGEGLCYFYDDGTHCKTVIDGEAVNAHWGVTKAGKPRKRLAIACVTCREKKIKCDPDYPRCVQCDKFGRVCRFKNAPRGGHNVAASSQTSTEDSSRRAVHFIRPSTEATSPLLAAPASAPPSIRPHISAPPRRPASPEPLSPHKRMRTSYDTYEHARTSSRLPSLPPPSQHHQPASYGHSSLSHMQHHEPWQPVRDISRDLPRLHESLSSTPWNRRDPYVAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z2J8</accession>
    <name>A0ABR3Z2J8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Ribosomal 40S subunit protein S9B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">RPS9B</name>
        <name evidence="11" type="ORF">Cpir12675_003659</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000090">
        <property type="protein sequence ID" value="KAL1894482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_uS4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018079">
        <property type="entry name" value="Ribosomal_uS4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005710">
        <property type="entry name" value="Ribosomal_uS4_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001912">
        <property type="entry name" value="Ribosomal_uS4_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003139">
        <property type="entry name" value="PRK04051.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01018">
        <property type="entry name" value="uS4_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="30S 40S RIBOSOMAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF5">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00163">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01390">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00632">
        <property type="entry name" value="RIBOSOMAL_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS4 N-terminal" evidence="10">
        <location>
            <begin position="5"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="RNA-binding S4" evidence="9">
        <location>
            <begin position="105"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="159"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1894482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="189" mass="21857" checksum="200F35CA7E34076A" modified="2025-10-08" version="1">MAPLSYSKTSRTPRRPFEAARLDSELKLVGEYGLRNKREVWRVQLTLSKIRRAARELLTLDEKDPKRLFEGNALIRRLVRVGVLDESRMKLDYVLALKVEDFLERRLQTCVYKLGLAKSIHHARVLIRQRHIRVGKQIVNVPSFIVRLDSQKHIDFSLSSPFGSGRPGRVRRKKAKAAEKGDEDAEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z3Z0</accession>
    <name>A0ABR3Z3Z0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alanine--glyoxylate transaminase</fullName>
            <ecNumber evidence="3">2.6.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_003257</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.44" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000074">
        <property type="protein sequence ID" value="KAL1895351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024169">
        <property type="entry name" value="SP_NH2Trfase/AEP_transaminase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21152:SF24">
        <property type="entry name" value="ALANINE--GLYOXYLATE AMINOTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21152">
        <property type="entry name" value="AMINOTRANSFERASE CLASS V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000524">
        <property type="entry name" value="SPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="7">
        <location>
            <begin position="24"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="384" mass="41179" checksum="A4A2CAE259B8C62E" modified="2025-10-08" version="1">MSTQPLHPLLLIPGPIEFDDAVLNSMSHYSQSHVAADFVSTFGDTLSMTRKLFQTTDPASQPFIISGSGTLGWDIVAANLVEHGEDVLVLHSGYFSDGFADCLATYGAKVTQLKAPIGTKPQLPDIEKALSEKKYKAITVTHVDTSTGVLSELKDLSALVHKVSPDTLIIVDGVCSVACEEIAFDEWGLDGVVTASQKAIGCPAGLSISMFSGRAMKAFESRKSPPASYFASMKNWGPIMKNYEAKKPSYFATPSPQLIHALNTALTLILAKPLSERFAKHIETSDKIKKYINDLGLSQVASKPEEQAHGMTAIYLPEGIKATDILPALGKAGVVFAGGVHKEIAPKYIRFGHMGVSSLNSERGDIEKALQALKSNLVALGYKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z428</accession>
    <name>A0ABR3Z428_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Vacuolar protein sorting-associated protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">VPS4</name>
        <name evidence="11" type="ORF">Cpir12675_003487</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000084">
        <property type="protein sequence ID" value="KAL1894795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02678">
        <property type="entry name" value="MIT_VPS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19521">
        <property type="entry name" value="RecA-like_VPS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007330">
        <property type="entry name" value="MIT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036181">
        <property type="entry name" value="MIT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050304">
        <property type="entry name" value="MT-severing_AAA_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015415">
        <property type="entry name" value="Spast_Vps4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045253">
        <property type="entry name" value="VPS4_MIT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074:SF83">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04212">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09336">
        <property type="entry name" value="Vps4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00745">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116846">
        <property type="entry name" value="MIT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIT" evidence="10">
        <location>
            <begin position="4"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="166"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="76"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1894795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="436" mass="48047" checksum="2660634C363882DD" modified="2025-10-08" version="1">MSKITDFLGRAIDTVKSAIEADNAQEYEKALNLYTKSLELFVLAIKWEKNPTSKEMIRNKTAEYMDRAEKLKTYLSEESKGGGGGSGGSGKSAQAMGSNTSSGKGKADDDEENKKLRNALSSAILQERPNVRWDDIAGLDSAKETLKEAVVLPIKFPSLFQGKRQAWKGILLYGPPGTGKSYLAKAVATEANSTFFSVSSSDLVSKWMGESERLVKLLFNMARENKPSVIFIDEIDALCGPRGEGESEASRRIKTEMLVQMDGVGNDSKGILVLGATNIPWQLDAAIRRRFQRRVHIGLPDSNGRARMFKLAVGETETTLQPSDYKELGHLSEGFSGSDISNVVQSALMRPVRKIMQATHFKELIIDSKRRLTPCSPGDPEAREMTYNDIESDELLAPHVEVKDFRMALKDSHPTVAQDDVAKQIDWSNEFGSEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4G0</accession>
    <name>A0ABR3Z4G0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">37S ribosomal protein S18 mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_003396</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000079">
        <property type="protein sequence ID" value="KAL1895124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="entry name" value="Ribosomal protein S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01310">
        <property type="entry name" value="Ribosomal_uS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_uS11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_uS11_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11759">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00411">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="47"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="47"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="61"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="292" mass="31460" checksum="94FFCB091FA55C6E" modified="2025-10-08" version="1">MTTLFCSRLLARPMASLQRSIQPSLALRTAVAPSAALVITRPFSCSIPRTNETQKPTESPATTTITASDDAAKKSSGSSSSSTDTPPKIAPVTEAPTSASTSSTSSALSSPLAHLYPSSKNTKDSTASTASEMRQLSHTLFAGVAKANSTNVQDADTPLTDAKAGEDDTLESFHFHVYSHKHNTHITVTRPNRNPIISMSCGNIGIRKSRRKNYDAAYQLTAYVLERLYHEGWQEKIRNLEVVLKGFGAGREAATKVLLGQEGKLLADKIIRVSDATKIKFGGTRSKNPRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4J7</accession>
    <name>A0ABR3Z4J7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Prolyl 4-hydroxylase alpha subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_003189</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000071">
        <property type="protein sequence ID" value="KAL1895551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF246">
        <property type="entry name" value="TRANSMEMBRANE PROLYL 4-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046263565" description="Prolyl 4-hydroxylase alpha subunit domain-containing protein" evidence="6">
        <location>
            <begin position="18"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Prolyl 4-hydroxylase alpha subunit" evidence="7">
        <location>
            <begin position="62"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1895551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="287" mass="31721" checksum="9FFD79B557AC4DC8" modified="2025-10-08" version="1">MLTYALILAAISAILYSQSAPKNLSRAPLPALNEDMLAIPSSNDTLGCPPDQYSVHIYSKEPLVIYIENFLSTSDQEHLLDVSEDLFQPSTVTHDGSSTQIDPSIRLSEVALLPRDPTVRCIEARARAFQGWRRNLWIERLRTQRYGPGGHYGMHFDWSSGAGGWGRVSSFMAWAHVSDDIQGGGTEFPYLPRAEVRSGNSFWCTFVECDASSTSSPEGGNEQQDILEHRPAVEGVIFKPILGNAVFWENFRADGSGKGYQETFHAGLPVKQGSKVGLNIWTWGALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4M9</accession>
    <name>A0ABR3Z4M9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclin-dependent kinases regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CKS1</name>
        <name evidence="5" type="ORF">Cpir12675_003170</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the CKS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000070">
        <property type="protein sequence ID" value="KAL1895585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.170.10">
        <property type="entry name" value="Cyclin-dependent kinase, regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000789">
        <property type="entry name" value="Cyclin-dep_kinase_reg-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036858">
        <property type="entry name" value="Cyclin-dep_kinase_reg-sub_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23415">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01111">
        <property type="entry name" value="CKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00296">
        <property type="entry name" value="CYCLINKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01084">
        <property type="entry name" value="CKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55637">
        <property type="entry name" value="Cell cycle regulatory proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00945">
        <property type="entry name" value="CKS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 4" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU311113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1895585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="105" mass="12429" checksum="344DBE8E176CBCE8" modified="2025-10-08" version="1">MPLGIDTSRRNKVPRILSDAERANLEEFIDGINYSARYSDSEYEYRHVQIPKAMLNAIPEDYRDPRTGTLKLLWEDEWRSIGITQSLGWEHYEVHEPEPHILLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z4P3</accession>
    <name>A0ABR3Z4P3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">von Willebrand factor A domain-containing protein 5A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_003646</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000090">
        <property type="protein sequence ID" value="KAL1894469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013694">
        <property type="entry name" value="VIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45737">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45737:SF6">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08487">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13768">
        <property type="entry name" value="VWA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00609">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51468">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VIT" evidence="3">
        <location>
            <begin position="9"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="287"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="508"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1894469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="935" mass="101543" checksum="E5736186D2156663" modified="2025-10-08" version="1">MLSPKPNFPGGLWTIVAARRANHPLVDSFAHTHITSYVSHTILTQTFVSNVASATQTHYSFPLHDGISVVSFSCGIGGKSIHGLVKEKQTARKDYESAASQGYNAALLELSQSAGDVYTISVGTVSIGATIKVTIEYVGELRHDAESNGLRFTIPTHIAPRYGASTDGVLSHNHPNGAFKLTVDTELAPGSEIKCINSPSHPISVNIGSISAELGPSIRFNPSKASVSCHLASAALDKDFVLNITATKLGEPMALLERHPTIPDEAALMVTLTPRFSLPPERAEQPEIVFMCDRSGSMSGTSIEGVRSSLRVFLKSLPVGAKFNICSFGSNYSMLWPKSRSYNNESFKEASLLAQNLQADMGGTDMYGALDAIFKQKSPQTTLDVIVLTDGQIWAQDHLFGLIRRTVQSSNGAVRVFSIGIGSGASSSLIEGIARNGNGFSQAVTDGEVMDRKVMRMLKGALSARIYDVALEVMYKSDLDCSVSTSGRDEDEDFEVVNRVSDCLIIESGEDDKSTRQGEPEEPENVCKDEPQHRNPVLIYDPAADVYEPALDSLNSDSDIRTVPDFPVPPIIQAPAVIPSLFSSTRVSAYLLLSGTAAQRTPKSIIMRASSPHGPLEQIIPVAVLDHPSETIHPLAARKAAQELEDSLGWLHQAKDATGTPLHVKYHNKFDDIVQRELVRLGVKYQISGKYTSFVAMERREDQSSAEIKDDLSSLLTPPMAMSVPQQLQFKRGNLSHSIYAMQMPTDKESINSQFLSRFTSSPSPRVHGAFSCCMSTSHRLTHYPSPSIRESYIETFVHDGPSALDHTPKPPSSFDTSPLLFLGRNSGFQPSEVAAPKSESAKSNLDIIINAAEICGSWEPDTELMEVLGTTVDELSRKAQGVGDSRILVTAAVIGWLEKEAAGKREIWELLVDKARTWLASQGHSAQELVEHLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z5D2</accession>
    <name>A0ABR3Z5D2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PhoD-like phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_003106</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000068">
        <property type="protein sequence ID" value="KAL1895773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="entry name" value="PhoD-like phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043904">
        <property type="entry name" value="PhoD_2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46689">
        <property type="entry name" value="MEMBRANE PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46689:SF1">
        <property type="entry name" value="PHOD-LIKE PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19050">
        <property type="entry name" value="PhoD_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoD-like phosphatase" evidence="2">
        <location>
            <begin position="1224"/>
            <end position="1478"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD-like phosphatase" evidence="2">
        <location>
            <begin position="1486"/>
            <end position="1655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="678"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="730"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="810"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="851"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="957"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1649"/>
            <end position="1668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1681"/>
            <end position="1791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1797"/>
            <end position="1816"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1881"/>
            <end position="1916"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1928"/>
            <end position="1984"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2032"/>
            <end position="2052"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2092"/>
            <end position="2146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2179"/>
            <end position="2237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="127"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="259"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="362"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="509"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="533"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="561"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="576"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="633"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="766"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="871"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="966"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="990"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1649"/>
            <end position="1658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1722"/>
            <end position="1734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1770"/>
            <end position="1782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1896"/>
            <end position="1914"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1932"/>
            <end position="1949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1954"/>
            <end position="1968"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2032"/>
            <end position="2041"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2095"/>
            <end position="2109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2115"/>
            <end position="2124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="2196"/>
            <end position="2205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2228"/>
            <end position="2237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1895773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="2237" mass="249086" checksum="4216D44A5AA5A8D1" modified="2025-10-08" version="1">MSSTAPYWGEDELTVDQTHTATASVSVVSASEAVRVKQQSEMTNDSFYVYDDDIQQQPSSSRRRSLQKHPSAKSKSHKHHSALSQATETETDLSNVSRQSPTSTTFQQPLTPRPPSVSMQPYVEPNAQFQATQASAAKATTLDSRPKTPLDTVAVEDAEAEERRRKRRGQRARQSQSQSAGDLSPLIPTSSSFNYAPPTSPTPITTTRTRTRDRVRDHGQESLAYTSPLQPLASAAAPASRNLQATPPLRSPPRPTRSPAPSSMPASPIPESVKSICSALPYSDIQSSMLPPSEVYSALPAEDLYSYHSQVNTPVLASPAEIRGQRTPVAPSPRPTLSVREPSMAQSSPRSVRSAREMPVTQSSRSIRSASAQEQGNILLQPSPQPIRSIRESPTSNLSPQPAHYIHETPVPQSPRSVKSVHDIQSGSARHVVINSPVVSPDTRRRSSVAIPRSRRKFADSHSPLQRLELTLDSMTKEEKRARVEAAERRARERSNLEVDKIHLGQQPPVDSQSPALSGSHAASRSPKIPNGSFRTANTTRHSSSPISTTPQGTPRKTFDLTSLHSTTASSANTTPAQVQPTHRSPLGQSSSDPHWSSLPPPKKPNTAESSGSHKRRPSVHGDMILPEGVRRISNSGGPQRSLSFRERRMSNSDDFDLNPGVVGSSYRRPTRIISPEPIDISVPETPAQQPAGWKSQQPAVGPSKPVKFEATVGASSISKEGIVPTAERPFMPDPILMDPHAPPPPPKRSSSFSFSSIGRRNSKKLQKDPPDDPFYRLRIESEKHQLHRAATIAATVAVKDQGADLAQNLGTDHVQQRSNVPVVRPSTASHNTQRPDSELAIEDIVKSMVDESYASDSSQEEAPRHLLRKRQQEQERNEHQHKVSNMMYHLAQDLKPGEGLYEPPSFLDEWRKGTVGTLSGSLLDLSQSHEQEIQHNQQQQTQIYPRGKLEHNDSAWWEAQPGNGTSTKSTTTTSTDTSRRRGSLSSRPRRAEAFDGEYDDRKDAPTKFRPQLYLKCGPLLRYTGIRRERHPGRFRVASAINNICDREFWRGTVMIVTKDDESHYEIAPTLRFFVQPIELYKPLDPNTKGPYDCVDPIASHPKVGRRGETLYVRPVDQIDSAMDLSRDETENGLYETSRTLRDGAAGITEIPGSFHARRKQVDIDGEALGKYKEVRGCRLHAERGLTFWRFNIEVELKEKSQRIAYRINRGPATGFWVPAKGQSMNIMFYSCNGFSATAHPDDYCGPDPMWRDVMNVHQSKPFHVMIGGGDQIYCDAVSQECGLLKNWLSIKNSIHKHKAPFTREMQDELEVFYLERYCTWYSQGLFALSNSQIPMVNMLDDHDIMDGYGSYPHHSMNSPVFKGLGAVAFKYYMLFQHQSITDETEESEPSWILGMKKGPYINEFSRSVLVDLGADVALLAVDGRTERTEFDVVSEDTWERIMDRCYKDVKSGEIKHLLVLLGVPIAYPRLVWLENLLTSRLMDPVKALGRTRGFASILNKIDGGVEVLDDLNDHWTAKNHKAERREIIEQLQDISMIKSVRVTILSGDVHLGGIGQFYSNPKFTVAKHKDFRYMPNVISSAIANAPPPHFLADVLNKRNKVHHFDKETDESMVPIFTNDVDGSPRNNKHLLPRRNWCSISPWTPDSTSIATPSLSNAETEETSAMPLQRRGSLLRRLSNAIPHRRKSISTADGEASVSRPPVTTVGWSGGLFRSLSQRSNRGREVERDAHEAHVSVTDSTSNIDLAEKPKRSLSVSRMFGFGKRKQKKNERDNDADSREVFSDDEYDDGYESSITEHLSAPVPRSADAGHSHGVTEDQIQALSPVQYANAHTQTGSSVLASRKDLISTLPSTATCSYSQSSLPMATMALDAQSKSFQQSSLLQSESSLDGIRGTPATNSRKNARTSSPLIQTYHNRRDDLSRHADRGSLMHGQQSDVYTTTNTASSLNDYDGDDRRPPSSRNRDHINETSTGNNRLRGGAASQLSEAEYSIGDETQFSVHPVHTQTMPATVAPDVTSAPGHGEVLANQSMKRSPTTFLTSKQRKQAPEPEVDLQGALEICLHMEIDPRNPNGQTVPYHLLVPRLFFSEEDERALEEHENAQEEEEQRRQNQLQYTQPQPSGNSGLADGLEDDSGDLQSRLPLAQRNARPSAFKRLISFRRKNKVQALKEEEERQRQLQLELDEYPDGSSLRSASDDDDYDEDDTVLGLEGHRRPAYDEEPYPEESQRYTLGTSGQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z639</accession>
    <name>A0ABR3Z639_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cpir12675_003115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000069">
        <property type="protein sequence ID" value="KAL1895724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAL1895724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="303" mass="33836" checksum="2EC09E7563AD6A96" modified="2025-10-08" version="1">MFWDIFTTASTGHEPMSTLLWSYYIHNSPYSPLKLSSLRQPTPNDAAASTPPGTFTFADAFEDLLAVSASRPMMPTQSRIEMRSLMRQVFPTTDEPPAFWLQRMDSAGLLAPNAQRFFTPDQYHPFFTHSDGTDGWKPSSGGLLDNADVFRKEFERATRDLATSEDDVKKAGQALEELAGLWTSAFETGAKSFGTFVDMVRHGAADISSDLDVLAKNKDTLQVTHTPNDDGKQADQSKYKTIESKDEYIDWMDMLHTKTTTKTLDENGNTVSSQSSWSMTNSYDKEKYKHLKDSKGNTSSGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z705</accession>
    <name>A0ABR3Z705_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cpir12675_003002</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000065">
        <property type="protein sequence ID" value="KAL1895962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF678">
        <property type="entry name" value="VACUOLAR AMINO ACID TRANSPORTER 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="241"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="382"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="476"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="10">
        <location>
            <begin position="18"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1895962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="502" mass="54001" checksum="CEF137C11B6A576A" modified="2025-10-08" version="1">MGNSMRTRRHGAKDGGGQATIQSSIVNLLNTIIGAGTLAMPAAISHMGIMLGVLVIIWSGMMSAFGLYLQSRCARYLDRGSSSFFALSQLTYPNASIIFDAAIAIKCFGVGVSYIIIIGDLMPGVMLGLNPNFEQVGYLMDRGFWITVFMLAIIPLSFLKRLDSLKYTSIVALVSIGYLVILIVYHFSVDQLAPAKEIRVVGWESPAAMLGSLPVVIFAYTCHQNMFSILNELQDNSPSTVGAVVGASIGSTASVYILVAITGYMTFGNSVVGNIISMYTPNVASTIGKAAIVVLVTFSIPLQVHPCRASIDAVFKWRPNANSREHARPGSAAGRSLLNPSAAAVSDHPVGSMSDVRFALITTALLVASYTTAINVTSLDRVLAYVGSTGSTSISFILPGLFYYKISDPDSVHHQRLAKADDDINEEFADDDDDDYNDSVVETAIAGSGLAKINQWRRHWRLDLEHINPGVLRKMALALVAYGICVMITCLSMNIFLGMSSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z853</accession>
    <name>A0ABR3Z853_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ras guanine nucleotide exchange factor bud5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">BUD5</name>
        <name evidence="9" type="ORF">Cpir12675_002969</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000064">
        <property type="protein sequence ID" value="KAL1895993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00155">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06224">
        <property type="entry name" value="REM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF354">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00229">
        <property type="entry name" value="RasGEFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="6">
        <location>
            <begin position="58"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="8">
        <location>
            <begin position="901"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="7">
        <location>
            <begin position="1080"/>
            <end position="1354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="255"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="661"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1251"/>
            <end position="1287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="267"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="286"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="325"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="345"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="385"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="669"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="687"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="717"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="743"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="769"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="803"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="837"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="857"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1251"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1273"/>
            <end position="1287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1895993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1362" mass="148259" checksum="73026670B21F0045" modified="2025-10-08" version="1">MYSQSQITPPATPRTGVDGFESRTNHIHHQQIIEEEEETQYDDQQEDYEETHVLQPPVFHNFLRAIFPFTPTTSSGEASVTLPLNEGDVILVHSIHTNGWADGALLASGARGWLPTNYCEAYNPEYMRGLLAALLSFWDLLRSTSVKNEEIFGNQEFMKGMIAGVRYLLERTDCLTRESPTIQRNDYMRRGRKSLLAELSTLVKIAKQLPDCQRGILPPGITDVSDIVDQMILKAFKIVIKGVRFLDLHEEDRRHRLPPSIDPPAVPVVAENSSASSVSSASSRSQTQPQEQLSHSMASSSIPPTPPADDTSSFDPPPAPLVDGSSSFETPSISSSDDVAVPIDTTGSATVTTTITAPGSAPTSASTSAASTPTTTPTFALSARTRSDVRESSSRRQSLLSYGPQNTHSVQTVVTLPNKRLSNAYSPGATAFGRNKPVNNNRLSFAGSTRVQRWSLGISHRMSVAGPASPLPAQQHLVSQRLSKSHDTFLSHLGSFIGRLQFQSQSHTELVLSIKQSATSGGGLLAVVDVVCFQTTVSADIITAARASMFERIQELVSAGHEIIKKSSPEETDAVMPQEKGVLIAAATGCVKAAGDCVAKTKWVVERIGDFEFELDESWSLGIDLSVLDFSSDTAATVTPSEPATHIVEDDSEKFAPSIDTVSEDRDAQQSQTSVSDSMSSDVRQSGTNESQKPQHTTKPSIAASLDKPLPEVPQVEVTTPGTTESYDNIETARHSTTSISHSRPASAQGSAAASPRQDNAPELTSPGLPASPKSSRLSLPPLPQISTTIDKVSSESHPDEVTSATTTEFQPSPTFETPATSSAESGTTHTSRDSESSMLSRTSTRATTPDGPRNKSSISGLSTNSSSKAESVVASHDADVEDDDNKLLVKTYAHELMFNKEGQVTGGTIPALVERLTTHESTPDAMFVSTFYLTFRLFCSPVRFAQALVDRFDYVAGAPHISGPVRLRVYNAFKGWMESHWRDQTDRDALSIIVPFADTKLSAVLPSAGRRLVELAQRVSHEGALVPRLVSSMGKTNTAIAAYISPDTPLPQVQISRSTINALNNWKNGGPSPSILDFDPLEFARQLTVKQMNIFSSIMPTELLGSQWMKKAGVDAPNVKAMSTLSTDLSNFVAENILGYTEVKKRAAAIKQWIKISYQLYELHNYDGLMAIICRLNSSTITRLRKTWDNISPKRREMLKNLQAIVEPQHNHKALRSKLHDHVPPCLPFLGMYLTDLTFVDIGNQATKQLHSNPATQEASTSMPSSPRLGGSDNNGSATNSKSNSGITVVNFDKHTRTAKIIGELQRFQIPYRLTEVPDIQDWISANLERVHGNDQGNVQVTYYRQSLMLEPREVAAAMQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z8A8</accession>
    <name>A0ABR3Z8A8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alpha 1,2-mannosyltransferase 2.4.1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">KRE2</name>
        <name evidence="6" type="ORF">Cpir12675_002622</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000053">
        <property type="protein sequence ID" value="KAL1896901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002685">
        <property type="entry name" value="Glyco_trans_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121">
        <property type="entry name" value="ALPHA-1,2 MANNOSYLTRANSFERASE KTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121:SF6">
        <property type="entry name" value="ALPHA-1,2 MANNOSYLTRANSFERASE KTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01793">
        <property type="entry name" value="Glyco_transf_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="39"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="41"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1896901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="421" mass="49186" checksum="88B1EE869431279A" modified="2025-10-08" version="1">MISTGGARYSRYLVIAVFALTVFLFFSSSSYNGVVLNNSRPTTSPETTSSPSHPIADPKNDGKRPAVGVPYDPADFPMPMNPGDPGWDDILVGTAPGPRMNATFVTLARNSDVWDIAKSIRQVEDRFNRRYNYDWVFMNDKPFDSTFKKVTSSLVSGQAHYAEIPKEHWSYPDWIDMDKEKKVRQDMAERKIIYGDSVSYRHMCRFESGFFFRQPIMMNYEYYWRVEPSIELFCDIHYDPFRIMAESGKKYSFVLSLYEYIETIPTLWDSTKKFMKNYPQHISEDNSMEFLSNDGGETYNRCHFWSNFEVGSLSWLRSQAYLDYFDSLDKDSGFFYERWGDAPVHSIAASLMLKKDEIHFFDDIAYYHVPFTHCPTNEKKRLDLRCHCNPKDNFDWKGYSCTSQFFDVNGMEKPEGYENQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9F0</accession>
    <name>A0ABR3Z9F0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">cAMP-dependent protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">PKA4</name>
        <name evidence="14" type="ORF">Cpir12675_002395</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.11" evidence="1"/>
    <dbReference type="EMBL" id="JAWDJO010000046">
        <property type="protein sequence ID" value="KAL1897291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05580">
        <property type="entry name" value="STKc_PKA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF37">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT PRKX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="106"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="13">
        <location>
            <begin position="426"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="287"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="64"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1897291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="484" mass="53725" checksum="6A7243607EAA62D5" modified="2025-10-08" version="1">MLWQCKQRPTDIASVATVTSHSTPSKFHPHHQSASIQTRVAATSALTASSINSRSHIYVHKTTRSNSNTPVTATPTLGQKSLAPSPPIYTVEEKCARNIPLNTEDFHLIRTLGTGTFARVCLVRPAVENEANRGRVYALKILRKTEVIRLKQVDHVRYERTILSAVAGHPFITRLHASFADSDRLFLLLDYIPGGELFTYLRRLKFFDEPMARFYAAEIVLVLEYLHETHDGIAYRDLKPENILLDCDGHIKLVDFGFSKRLGNGHGDGNDDTFAAAAAGDSKKSLAVSKTPVSSGAKNKENNGSEKPASAPSPGLYASETYTLCGTPEYLAPEVLQNRGHTGAVDWWALGILIFEFLVGYPPFWHQNPIEIYRQILETKIQFPTSPALSSSAQDLILRLCTTDRSQRLGNMAGGAAQVKQHPFFSGIDWDAIAQRRCTPPILPLVRHAADAQCFDVYPEDDGSTRGEYTHDLAEVYDEQFVDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9F1</accession>
    <name>A0ABR3Z9F1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Transaldolase</fullName>
            <ecNumber evidence="3 7">2.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TAL1</name>
        <name evidence="8" type="ORF">Cpir12675_002390</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:17053"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transaldolase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.2" evidence="3 7"/>
    <dbReference type="EMBL" id="JAWDJO010000046">
        <property type="protein sequence ID" value="KAL1897286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004801">
        <property type="term" value="F:transaldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00957">
        <property type="entry name" value="Transaldolase_TalAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004730">
        <property type="entry name" value="Transaldolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018225">
        <property type="entry name" value="Transaldolase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00874">
        <property type="entry name" value="talAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="TRANSALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683:SF18">
        <property type="entry name" value="TRANSALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01054">
        <property type="entry name" value="TRANSALDOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00958">
        <property type="entry name" value="TRANSALDOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0704">Schiff base</keyword>
    <keyword evidence="4 7 8" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1897286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="324" mass="34787" checksum="7BB35001900544A1" modified="2025-10-08" version="1">MASSLDQLKASGTVVVSDSGDFASIAKYKPQDATTNPSLILAASKKPEYGALIDAAVAAAKAAGGDEETQIEAALDNILVEFGSKILEVVPGKVSTEVDAHLSFDVKASVAKALTIISLYEKRGISKDRVLIKLASTWEGIKAAEILQRDHGINCNLTLMFSLVQAIGAAEAGAFLISPFVGRILDWYKAATKKEYSKEEDPGVASVKIIFDYYKKFGYKTIVMGASFRNTGEITELAGCDYLTIAPSLLEELLNSTTPVPQKLNASSAAALNIERKSYINNEAAFRFDFNEEQMAVEKLREGISKFAADGLVLKSLIKAKLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9H4</accession>
    <name>A0ABR3Z9H4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">37S ribosomal protein S12 mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_002623</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000053">
        <property type="protein sequence ID" value="KAL1896902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03368">
        <property type="entry name" value="Ribosomal_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_uS12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005679">
        <property type="entry name" value="Ribosomal_uS12_bac"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00981">
        <property type="entry name" value="rpsL_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01034">
        <property type="entry name" value="RIBOSOMALS12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1896902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="188" mass="20121" checksum="559A77C2DC7A610A" modified="2025-10-08" version="1">MVVGMLFRRLATAAPSWRPMARISSPVLAAPAVASIVKPSLALRDIAARAFSTTPARPATIMQVLRGCRKGKRARHATSPALSSIDAPMKKGVCLKVGIVRPKKPNSGERKTARVRLSTGRVITAYIPGEGHNIQQHSVVLVRGGRSQDCPGVRYHLVRGALDLGGVNNRMTSRSKYGAKKPKKATVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9R4</accession>
    <name>A0ABR3Z9R4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.256</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Asparagine-linked glycosylation protein 10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">ALG10</name>
        <name evidence="17" type="ORF">Cpir12675_002606</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the third and last glucose residue from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide intermediate Glc(2)Man(9)GlcNAc(2)-PP-Dol to produce Glc(3)Man(9)GlcNAc(2)-PP-Dol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>an alpha-D-Glc-(1-&gt;3)-alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-glucosyl phosphate = a alpha-D-Glc-(1-&gt;2)-alpha-D-Glc-(1-&gt;3)-alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29543"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19502"/>
            <dbReference type="Rhea" id="RHEA-COMP:19512"/>
            <dbReference type="Rhea" id="RHEA-COMP:19522"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57525"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:132522"/>
            <dbReference type="ChEBI" id="CHEBI:132523"/>
            <dbReference type="EC" id="2.4.1.256"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:29544"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ALG10 glucosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.256" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000052">
        <property type="protein sequence ID" value="KAL1896957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106073">
        <property type="term" value="F:dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016900">
        <property type="entry name" value="Alg10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12989">
        <property type="entry name" value="ALPHA-1,2-GLUCOSYLTRANSFERASE ALG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12989:SF10">
        <property type="entry name" value="DOL-P-GLC:GLC(2)MAN(9)GLCNAC(2)-PP-DOL ALPHA-1,2-GLUCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04922">
        <property type="entry name" value="DIE2_ALG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 17" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="397"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="521"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="593"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="488"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1896957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="636" mass="70774" checksum="37DB691C256723B3" modified="2025-10-08" version="1">MLELGQIFGLMANILPVVTPIVVLAGVEHLFLPQADHKLSDEIFHVPQAQTYCRGRFLEWDDKITTPPGLYLLSILAMKVRLLFVGDPCSAFMLRSFNVWSIAVVALLASLCRRRIEASLARKENRGSISGYSIHTGLNIALFPLVFFFSGLYYTDVLSTVSILAAYAHHLNRISSSSSSLISDFVAILLGMAALFMRQTNIFWVVVYMGGLETVHAVKQSKAPTGTKMVPQSTLLGRINSSLQKYSRGKIHDPPISSCWPDDIIFSLFSISVAALCNPLRVLRQVWPHITIMALFGGFVAWNGGVVLGDKSNHVATIHLAQMLYIWPLFALFSVPLFIPSLLSSINTLIDLPSQLRALFTTKERSRGVEGGGSGEEASGLKWACLFFTYRIYYFPYIAATFILSALVVKFNTIVHPFTLADNRHYMFYIFRYTIRRSEAARLALVVPYSICRWLSWGALASSAQPMVGYKPQDSCLFDNHPVLAASSSAGKNERRPSQPGGRSSVTALDGDSTPCIPTTASTVAILFLATSLSLITAPLVEPRYFIIPWVMWRLLVPAWAMQDLSLTSLSFVTKLPLILGVVRFSNRYDVRLFIETAWFLAVNAATMYIFIAKAYTWRAEDGTVLDGGRLQHFMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3Z9X9</accession>
    <name>A0ABR3Z9X9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">H/ACA ribonucleoprotein complex subunit CBF5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CBF5</name>
        <name evidence="11" type="ORF">Cpir12675_002734</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a uridine in mRNA = a pseudouridine in mRNA</text>
            <dbReference type="Rhea" id="RHEA:56644"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:14659"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>uridine in 5S rRNA = pseudouridine in 5S rRNA</text>
            <dbReference type="Rhea" id="RHEA:47036"/>
            <dbReference type="Rhea" id="RHEA-COMP:11730"/>
            <dbReference type="Rhea" id="RHEA-COMP:11731"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>uridine in snRNA = pseudouridine in snRNA</text>
            <dbReference type="Rhea" id="RHEA:51124"/>
            <dbReference type="Rhea" id="RHEA-COMP:12891"/>
            <dbReference type="Rhea" id="RHEA-COMP:12892"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the pseudouridine synthase TruB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000056">
        <property type="protein sequence ID" value="KAL1896638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02572">
        <property type="entry name" value="PseudoU_synth_hDyskerin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21148">
        <property type="entry name" value="PUA_Cbf5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="entry name" value="PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012960">
        <property type="entry name" value="Dyskerin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004802">
        <property type="entry name" value="tRNA_PsdUridine_synth_B_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032819">
        <property type="entry name" value="TruB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004521">
        <property type="entry name" value="Uncharacterised_CHP00451"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00425">
        <property type="entry name" value="CBF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003280">
        <property type="entry name" value="PRK04270.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00451">
        <property type="entry name" value="unchar_dom_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23127">
        <property type="entry name" value="CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23127:SF0">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT DKC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08068">
        <property type="entry name" value="DKCLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16198">
        <property type="entry name" value="TruB_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01136">
        <property type="entry name" value="DKCLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="Dyskerin-like" evidence="10">
        <location>
            <begin position="29"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="PUA" evidence="9">
        <location>
            <begin position="297"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="423"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="433"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="472"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="491"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1896638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="517" mass="56781" checksum="0C5D17425650D126" modified="2025-10-08" version="1">MTTDVAKVSKAQQKDDHVLQPTSSVPTIDTSSWPLLLANYDKRTYGSAILVPGVILAFVLFLIRTNHWTPIPHGSSPLKRDLKSYISSGVINLDKPSNPSSHEVVAWVKRILRCEKTGHSGTLDPKVTGSLIVCIDRATRLVKSQQSAGKEYVAVLRVHGKVPGGTAQVARALETLTGALFQRPPLISAVKRQLRIRTIHDSKLIEFDNERGLGVFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGAMDETKNLVTLHDVMDAQWVHDNTRDESYLRKIIQPLETLLVGYKRIVVKDSSVNAICYGAKLMVPGLLRYEDAIEAHEEVVLMTTKGEAIAIGIAMMSTLEMTTCDHGVVAKVKRCIMERDLYPRRWGLGPVALEKKKMRADGKLDKHGRINENTPAKWKSEYKDFSGQIDPTTAIIGHPASSVTPAADTTSAPATPAKPAASKTETETPAAAETPAGEEGKKRKKHDGETAEERAERKRRKAEKKAAKVSKKGKADAMDEDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZA70</accession>
    <name>A0ABR3ZA70_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002466</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0047 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000048">
        <property type="protein sequence ID" value="KAL1897209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.460">
        <property type="entry name" value="YjbQ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001602">
        <property type="entry name" value="UPF0047_YjbQ-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035917">
        <property type="entry name" value="YjbQ-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00149">
        <property type="entry name" value="TIGR00149_YjbQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30615">
        <property type="entry name" value="UNCHARACTERIZED PROTEIN YJBQ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30615:SF8">
        <property type="entry name" value="UPF0047 PROTEIN C4A8.02C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01894">
        <property type="entry name" value="YjbQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004681">
        <property type="entry name" value="UCP004681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111038">
        <property type="entry name" value="YjbQ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01314">
        <property type="entry name" value="UPF0047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="153" mass="17292" checksum="08FB4F9C84F43C31" modified="2025-10-08" version="1">MSWSQKQFSLPARSRGSYLVTDLIIDALPEIREYKVGLLNLFIQHTSCALSLNENWDEDVRHDMTDALEKIAPYEGPKGEALYRHDAEGRDDMPASFPFSIAHIKSSLIGASVTIPIKDGRLATGTWQGIWYLEFRAAKHVRKIMATIQGQKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAM6</accession>
    <name>A0ABR3ZAM6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_002498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000049">
        <property type="protein sequence ID" value="KAL1897177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1897177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="264" mass="29095" checksum="EE3CA8398649EAED" modified="2025-10-08" version="1">MNFQVMSPNELREIAQQLHTALRQSHNQQHALLNALTQLRAERQAQPAATASTAAGHAGQPTTRDSTRGHAARNFTNVDAPLGQAAGHQPLLRKLDWLQTVGHDDAVQGGDRRKSHRDGASPAGIRITVLRRAVKPRLAGAPLLGTRPASYHEFVLTTFGLASDLEAFDTDRYRRSETWNGNRDTRTSANTDVMDWQATDAVQLKPLTIDERGSLRKKGACFRCRKTGHMRSERPTAKQQRVIMKAAEISHPGPAIPELTVAEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZAW0</accession>
    <name>A0ABR3ZAW0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">MEC1_2</name>
        <name evidence="17" type="ORF">Cpir12675_002237</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Associates with DNA double-strand breaks.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PI3/PI4-kinase family. ATM subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="JAWDJO010000041">
        <property type="protein sequence ID" value="KAL1897738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00892">
        <property type="entry name" value="PIKKc_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056802">
        <property type="entry name" value="ATR-like_M-HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057564">
        <property type="entry name" value="HEAT_ATR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012993">
        <property type="entry name" value="UME"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF125">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE MEC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23593">
        <property type="entry name" value="HEAT_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25030">
        <property type="entry name" value="M-HEAT_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08064">
        <property type="entry name" value="UME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00802">
        <property type="entry name" value="UME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAT" evidence="15">
        <location>
            <begin position="1418"/>
            <end position="2000"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="14">
        <location>
            <begin position="2113"/>
            <end position="2420"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="16">
        <location>
            <begin position="2417"/>
            <end position="2449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAL1897738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="2449" mass="275612" checksum="B45A6BB7C61C9A6E" modified="2025-10-08" version="1">MNAGDCHDPPSTLAAQLVDGITNRPSRSSFHVHGTGSDEDDELKRLIAGAMKIKEDPNAIKTEEKHLEHNHLLLYAYVRLRLKEIFVDSTSITSSTQARIKQDLNDVTKFIEITLKETKRLLDHKDTSDEFLLRGNEPFWMWLMPKIMCFLGHEKCIENTDELEDSLACMVYTAMQIKETNPDVYRILEYLKDAVNEISAVLLNPNIKADQPFQIDLPPTATLERICSSGGNDQADWERLQYRVCDPGRLIGQATSFLRILTNHALLEAQEDVILEYGLWILDALQCLGTATLNFHADFKSDITPILKIALDILDSDRFKTNSSHIIFQEKAPIVLVLLCSEIASLPQVLMEENDNGQACQHTFARALIKLVGHCIVRPEVAHIVTSNILPKLDPAVSMYAPGPDFPRILTLLTEASENVSPAFSFGFSSRPELFVDSSLRKCVEKLHLNWVSSDETGQPDAKRRKTKEEEDSKIPILHGIIFKRLHIDLDGESMVTVIVNAFPHMSLGDKCLIIELISHFACAADKTLEMDIDHVAHTTTIHCGYCQTPEVAPMKDTEQSLSAKSMLFRTLTQLIALPEFESSRKPRVVAMLALQKLALHFHSTDLYDLEQSKLGLWCLKSLRSSIRELRIAASRTFPLFLRHTAFSGVDANVITRNRIHVIGFLKQISHKEASHLHETCIMAWGQLGRQESLNPQNPIPTMVELLGSTSHVVSTIAAVEIRALAKSRGRTTSKMFEPFWKYMSYVVVKNFAGERRRCTKVAELLGLDLIDLLVLVQRHALPWLVLENDIETIKAIAAAMSKEVTPLLMSKGNLPPILALLMVNSVENTEAAVMSQLCRVGDEFKNSDLMALIRSELVPTIHELFKHAATRDDDKRKAVLCALKWCSVRLMSSRDPKRKSPDVIGYALEPHMLGLVSSLTEVINIALTSQQVTVEQTQCIAAMEEMIKICKSHVRTGRAQISASLLSVMTLEELRRPALSAWAAMVLNLDEADAVLLLEPTYYVVIQYWIMFDAASKTMAEKLILDLYAKYPEMFNDNIFKIPSLRHTPTLAKLEDELGVIKKAALEATSVKKMFSVYVERITHENSGVVWLGLGDLITFLKTHQSWIQASALSESPDDVVSMLLRALLDCAARFNGLDYDICCMCTECLGLIGCLDSNRVEATKEQRSIVVYNNFTKEHDKAEFGFFLLTEVLLKSFSSTTDTRMQGFLAYAMQELLERCDIKALVTGPGTRGGNDIAREWALLPSVDKELLNTFMFSRYVLNSNIPPTAQMPSFRPDGEYSQWLKDMVFFLIQNPQNPNAALIFEPLMRLVRVKDTSVAEHLLSYVFCHVVIGCESSIYKKLNEELLAILEFDPTNIHSPEEKRHRNRYYESVFSILDYMMRWVHKKKVAPRLDNAQTAELERVQKFLDNIPPQLIAQRAITCNQYNRALFHLELHVRETSTKKGRIDGENKEELMAQLQEVYAQIDEPDGLEGISAHFQVLDLEQQVLSNKKAQRWTAAQTWCEYRLSEEPENTDIQMELLTCLKNSGQYDVLLSYAESLRKHPALENKISSFAVEAAWATGRWEDLNKLVRSYNGNILDDFNLSIGEIFRCLYNKEYESIPDTITMIREKISAALTTTTTSSLQACRDLLLQCHVLSDLEMILANKPKTPQETPPNNDAIMANLSRRVGVLGSFASDKHYVLGVQRAAMNLMCDAYTNLNISSLWLASGKMSRKAGLLQQSFNSVLHASNLGDGSAIIENAKLLYKEGHGRRAIQILEAAIAGNKLSAQSQQAQPSVKTSGTGSVTSSKGADYAQKLLIARAQLMIAKWLDATGQTNVLALREKFQEAAKTCQAWEKGHYWLGRHYKKLLEYESKLTPDEQTDATLMGTVARVVIENYLRSLNFGTKYLHQTLPRIITVWLEFAALFDESPTARAAMAHELKRRRLAELNAIHACIEKFTRRLPAYVFYTALPQMVARITHKNADAVKLLVNIIAKVIASYPQQALWGIFPLLMTPRNAERSSRGKEILSVIRAADPKLDGKPVAEIIRKGEKLAAQLVWLSQTGDFQSNRSTMTTLNQLKFNANACLPSPLVVPAESCLMAKLPTLPESSKRKHQPFSGDVVTIHSFEQEVLVLGSMARPRRVIAIGSNGQKYKLLIKPKDDLRADQRLIEFNNVINKALKKDPESSKRQLYVRSYAVTPLAEEGGIIEWVDGLKTLRDILLMLYKQRGLSAINYQQLESVCKAAANDATLFTRDVLGKFPPVLHVWFIDNFPDPTSWFTARLRYTRSCAVMSMVGTILGLGDRHGENILLEEGNGGVFHVDFNCLFDKGLTFSTPERVPFRLTHNMVEAMGIYGYEGPFRQCSELTLATLRAQKETLLTIIEAFIYDPTIDLLKDKGRRARPDGRVRMNPQSAHEGVKRRLLGFLPNELIPLGVEGQVDELIKQAVNPKNLAAMYIGWCSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB23</accession>
    <name>A0ABR3ZB23_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycoside hydrolase 131 catalytic N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002156</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000039">
        <property type="protein sequence ID" value="KAL1897813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041524">
        <property type="entry name" value="GH131_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34612">
        <property type="entry name" value="GH131_N DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34612:SF2">
        <property type="entry name" value="GLYCOSIDE HYDROLASE 131 CATALYTIC N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18271">
        <property type="entry name" value="GH131_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046741455" description="Glycoside hydrolase 131 catalytic N-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="16"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase 131 catalytic N-terminal" evidence="2">
        <location>
            <begin position="21"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="289" mass="31356" checksum="DF9B0FFE8F00D798" modified="2025-10-08" version="1">MQSLSLLALIAPVAAQMCQLAFDGRVAKDFALEGFDADTSPFNPSNVFGKGLKWSEILKFPTGNGGLFDVDTQPIEVTINDTSIFAPSETNVQIGFRRAELLIASNSGTDPSTTGIKTLHFSLKKDDQRPLNISHEYQLVFIEDSSYSTNQFVLKTGTILSGDGASDPDTLQLFGNVNQKEPGMIFSAPFTPGTFHNFGLKLDFTANTTQVFYSTGNCELTQQTEPITNDISGQGQFHFGILKKPTGETTDVTKSGFQPEDIDEGIIYTSIFSEDSADGCMSLSPTKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZB26</accession>
    <name>A0ABR3ZB26_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Alkaline phosphatase</fullName>
            <ecNumber evidence="4 11">3.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">PHO8</name>
        <name evidence="14" type="ORF">Cpir12675_002422</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a phosphate monoester + H2O = an alcohol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:67140"/>
            <dbReference type="EC" id="3.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the alkaline phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.1" evidence="4 11"/>
    <dbReference type="EMBL" id="JAWDJO010000047">
        <property type="protein sequence ID" value="KAL1897240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16012">
        <property type="entry name" value="ALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.60.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001952">
        <property type="entry name" value="Alkaline_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018299">
        <property type="entry name" value="Alkaline_phosphatase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596">
        <property type="entry name" value="ALKALINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596:SF5">
        <property type="entry name" value="ALKALINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00245">
        <property type="entry name" value="Alk_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00113">
        <property type="entry name" value="ALKPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00098">
        <property type="entry name" value="alkPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00123">
        <property type="entry name" value="ALKALINE_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8 11" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1897240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="578" mass="63167" checksum="A0B873B78F32394C" modified="2025-10-08" version="1">MNPETESLLPSGHRDDPDEPIPNDPPSVRFLQTKSRFCDIKMFIWALLVTALLVITAVWTQNPHHHHDISEPSPNNPVTGKRNLIFMVSDGMGPASLSMTRSFRQYIRGESFDKPLYIDHRLTGTSRTRSSNSLVTDSAAGATAFSCAQKSYNGAISVLPDHSPCGTILEAAKRAGYLTGLVVTTDITDATPACFSSHVQTRAEMDDIAVQQIGLGPLGRSVDLIFGGGRCHFLPTSKGGCRADDKDLIANATKDLGWNYAGDREAFDKMRRGENVDLPMLGLFADRDIPFELDRRNEATVYPSLSEMTVFALRALEKASKSNEKGFFLMIEGSRIDHAGHINDPAAQVHEVMEYDRSFQGVSEFLMISQDEGALVATSDHETGGLATAIQEPGQLPMYNWYPAALAAATISSERLALMLQEHISSDEFQAQSRHDLKAWINETLVFGGLGVNDATQDELNDLVDNPDASINTFAAIISLRAHIGWSTHGHTAVDVNIYTSGGANTSALQGDVENTDVGKFLQDYLDVNVDDVTKDLRKAFKFSESEAVKTEGQDDIIQRGTKAAMDAMLRWVPGLNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBS6</accession>
    <name>A0ABR3ZBS6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)</fullName>
            <ecNumber evidence="2">1.2.4.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_002204</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + 3-methyl-2-oxobutanoate + H(+) = N(6)-[(R)-S(8)-2-methylpropanoyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:13457"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10497"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83142"/>
            <dbReference type="EC" id="1.2.4.4"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:13458"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.4" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000040">
        <property type="protein sequence ID" value="KAL1897779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07036">
        <property type="entry name" value="TPP_PYR_E1-PDHc-beta_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42980:SF1">
        <property type="entry name" value="2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42980">
        <property type="entry name" value="2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="5">
        <location>
            <begin position="56"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00051764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1897779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="381" mass="41645" checksum="C7A16C1B64E999DA" modified="2025-10-08" version="1">MAWKWQRAAYSSHPLSARLNVPIDYSATPLLAQHNQTALRNPELPDAIRGGPTQRMNLFQAINDALSTALSEDERVMIFGEDVAFGGVFRCTTKLAETYGSQRVFNTPLCEQGIMGFAIGAAAEGMRPVAEIQFADYVYPAFDQLVNEAAKYRYRDGACGRHVGGLTVRMPCGGVGHGALYHSQSPEALFTHIPGLRVIIPRSPIQAKGLLLGAIRSNDPVVFLEPKILYRAAVEQVPVGAYTLPLSKAEILKAGKDVTVVSYGQPLYNCWAAIDKAEKDLGISAELIDLRTVYPWDKDAVFGSVRKTGRCIVVHESMVNAGVGAEVAASIQEDEQTFLKLEAPVQRVAGWSVPTGLLYERFNLPDVARIYDSINKAVTEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZBT1</accession>
    <name>A0ABR3ZBT1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_002195</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000040">
        <property type="protein sequence ID" value="KAL1897770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047208316" evidence="2">
        <location>
            <begin position="20"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="463"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1897770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="496" mass="53835" checksum="10D316D8FBD36B50" modified="2025-10-08" version="1">MTRIILLTGAPLPAALLEAETTPGTSSETSTGAHNEAQTEAHAVKIATSPFSSLMPCFEPCYARIDKSLPIRPKVTSTHTHTDHRSKEPAPWRVLSHSHSHLPTSFSQASRATDFLNLDLLQASSADPPQSSTSISPSPTRSAPQGGDGLTTLLNQSWSCILDDSNSAIPDLAEDIPGDTNKPPSLNPLLQFYEESILLYSVLDGDADVTSTSVAEPPLQSHVTGHPPSTPANISTYFSLETDSDIDTTISMSTILPPHSPTPSLQTFLPGASRPLSNLKDLPSSAQLARIQQQESRSPFPLRQNPVLINLIVGIISISFPRTITTRWGSRLQLVELLVGDNTRAGFSVSFWLPLATQSGLSRPVQSSNLATLLALRRQDIILLQNVLLASFANKVFGQNVKGGDTSVNLLYRHYNASLPKHQPAQISGHYSSADLQARTTAHPQLEKTRCVRQWVINFVGSGPIAPKRPDDGHNKPGREMKRQIRTWDQPPPDSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZC24</accession>
    <name>A0ABR3ZC24_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ras GTPase activating protein ira2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">IRA2_2</name>
        <name evidence="5" type="ORF">Cpir12675_002298</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000043">
        <property type="protein sequence ID" value="KAL1897570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05392">
        <property type="entry name" value="RasGAP_Neurofibromin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054071">
        <property type="entry name" value="PH_NF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039360">
        <property type="entry name" value="Ras_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023152">
        <property type="entry name" value="RasGAP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10194:SF142">
        <property type="entry name" value="NEUROFIBROMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10194">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13716">
        <property type="entry name" value="CRAL_TRIO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21877">
        <property type="entry name" value="PH_NF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00323">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00509">
        <property type="entry name" value="RAS_GTPASE_ACTIV_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GAP" evidence="4">
        <location>
            <begin position="1181"/>
            <end position="1374"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="170"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1897570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="2491" mass="278870" checksum="70152BCCEB0CAEA7" modified="2025-10-08" version="1">MDPRWDTSLVECLFERLMSKLPHKTRATQQDLAHDEVLNTTHATIVSLSVTSITLVLEYAVGLLNDLIPSPNNPVEGHVLQSQIYVSSLIADCCSANWDAVRAKNNSDSAHIIPDCLDEELVSHIFDAVRLLLDPFPDNFVLPSNTLLSANATNFPRALESRVDELYDGVISEKSNLEALRADMSKLDENIKTLLQFVSASSWSSCFEYSRVIVYALRAVPTTGASSTSQQSTMKDDERAAAIFLRCMSFFWIDGAKLGTVMSEIASTYLHLKPQLKNCVAVVMPILITNWIDRFPDEFVHLHIHHVKLSGAIEMLFDMCHSETVKIRQLYVPMQASLLLLLPEVFEVVSSLTTVKSSAKSKRVVLLDNLKKAIRNKNQYACFCLVMLLRAGRHFVSDNDSAFSSFALDIQDEIRDAVFRNFSGSSESPFLDQDMITASLVALAHLDVDGVAESLLESCLIPSAPLSFKLAVVQACQYFASLPNHSQYRPLFNASAPFIYAQLRAISNGKTSAVLPDSSSSELSPNKAVAAMAQGIMGFLKASNGLMLYQSSIDNPDETNLFRSLIFCLVSTDREVRKLAADLSCSLFDDSPEAKERRPGLEALTTCDWHEDYWRRSANTLMSICSELDKHTSQARLQHLEHNLTARVLVLQEFPILSKLERDIPEMATAASQIETTLLLLLCAVDINVCQLVTSCIGLFLQESILLLNTSGSGYQTSLMRNRLVFDELASKDFRFTGLVAFQKRTRGLFRRLHCPTPGIIYAWEIAFERWIQISRDVSASSLEPIADTTLTKWRNYSGMLASVGGICTAERSATLDEPTMSSNFRWIDRTADQQDEPSLLRYLRLSIKLLACSNIRVREATREVLSTEISPFLYQQLFTALSIELDVLFNGNLTPNDRAVEREIIFAEQAASLIRTLVERLETPADAGAAASVHLGAMTLNFAKFMEGVVDNSTTIRVKIKICQLCELVAHRKEFLNLRDDVQVRNQLLEYVFSWISRPKTPRPEAHLSSRHDESSRMQKDLDKACLKCLSELTYRLPLQPTSSDGQSDAGASELKSQLFQTYFNRFLSLLNHDNTETRRMDLSSRDDHLIPDLSITILSNLLSSNIDVGLKHSLNIGYHENLEIRTAFVKVLYNILIQGTEFSNLSDTAVSEKHTQLLDILTSDVSLAVALSVVCPANEVDEMAISLLVVYEQRGKGFQLIEALISQEIDDTDSEAEILRRNCVATKLLSIYAKWQGSAYLKATLQKVVERLMITSKELNLELDPSRVTSAEELQNNAIQLRIVAKVFVDDICASSANIPPCFRKICSIISSAVLPRFPDAKYTAVGAFIFLRFFCPAIVAPDVEGIISNPPSKEMRRGLLLIAKVVQNLANNVLFGAKEPFMFPLNDFLTENIYRVTTFLREISGSPMGDIEPSSAEWSEFGSCVSLHRFLYDHWDHFRQRLTYQERREQARSPAESQRTRSPFDGMPIVCIIMRYIDVETVDYDAIIYWYLKIVSRLWSRPFGLLIDATCYNGHVETPEDLFERLEKLSPVELSRSLSRVYIHNMNSTFRSCLRRLLRASSRNRGSVFNPNNVHYHLLGGRYDLQAHFHLSQLNLPKETISVVTDTRFVFQPVTKLSRMRGDIDVTITVGTYFIQVTTNEKQEVHSTSRISGIVNDTFRVGEVEDMPSSMGLDDDSGFGLRADNGKFVMQFKSSKTTDIIQAIRGTKAKNGKDNRSQKMFERLVRPQDVPGTLLNLALTNLSSPDHTLRLASYNLLGALCRAFKFASAGKLLCLKGISIPMVPASFVLRISTELATTEPQLTQDFLTEFFVGWDSFSEDQRPLSMAYMAPWLPGLRIHILTNETDGEKAREKVAIILRKLVDVAMSDHLLTFTLEKTVWPHISRDEVLVEILLEELTRTALKISIQDSALEALASIAASIGTVTIRGKIIARLRKVLNRSSMRPTRHLPDNSVWGEICILLRFCLSLSFDSGVQAQLYLPDIFHIVTMLANTGPPDVRSVVHRLLINSLHSISTSFSLNETQQTKLLSTLEYLDEPRSELFLLLTATRDGGASFTTAQEQGVPSLNAVEALANLLIEVCAISAPNLDAANTWRARWMSLVASTAFQVNPAIQPKAFTIMGCLAQGDVDDDLLYQVLVSLGSSITRYCEDGIADLLVSIVTALSKMMTKLPSTSRYGLQLFWLAISMLRFLPSSLFNYAAQLLEAFLNNVYLSENMTGQKLIPLLLQARSQLKDACFALDETHGIPFTPDNFHFAVCACLVRGLTDTMTRTTTMRVLSVFLDVMEPAMPSASEDSEGSGSNASMKITTQSPYAALMLSRCVGLEELNDRLWFPGINPQTMDDSILQWRLHDLDSVKDKDLLLNTCIELVDFQDLDAPIQNRSLRWLTSVALRRPSVIIHLYSHLTGVLDDILYHSQISSTLQSAYELLQCLITNPKFATANSQNVEPYGVLIDLGFSKIWQSCSYNSNNEPDPEFAVQLKDLINLIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDB7</accession>
    <name>A0ABR3ZDB7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Polyamine aminopropyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001975</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000034">
        <property type="protein sequence ID" value="KAL1898349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF037959">
        <property type="entry name" value="MFS_SpdSyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43317">
        <property type="entry name" value="THERMOSPERMINE SYNTHASE ACAULIS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43317:SF1">
        <property type="entry name" value="THERMOSPERMINE SYNTHASE ACAULIS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01564">
        <property type="entry name" value="Spermine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="583" mass="63259" checksum="6C6F124DCDCF65B4" modified="2025-10-08" version="1">MVKKPAPSAPAPQTSNDAAMTSARFEKELRDLKHKAESRSPLQDSIACAAPIIRSALLLLLLGLSSTVSQLALSPTFGGIPTAVHHSKLTATGCFLGWASSMTLSRFFGKDLVKLLPVIAIWIPALQFILGGESASLGAEWGPAIVESVTLLPLIVISVAEVALSLEGMSIRLLPGWIGDSLPGLVGFLFFKTVESVSSMRIPMLLGSSALASRVGLQLAFAAVYTLYAPSQFLLLGLPAVAHVALFNTHLPTAAATATLQASLEEEAWKLIARKESVTGYVSVLESVERGFRVMRCDHSLLGGLWVKFTNGKVAEPVYSVFVMLEAVRLVLTKETIIDSTANALVIGLGIGTTPGAFIAHGINTTIVEIDPAVQEFAVDYFGLSTNHIPIIEDAVSYTSALAKTNPESFDYIVHDVFTGGAEPVPLFTLEFLQGLKDLLKPDGVIAINYAGDFLLPPTKAVVKTIRSIFPSCRIFREIERQSDEQIKEQNQDFANMVIFCRKSSEPIDFRPATDDDFLGTGTRKLTLQPRYEVKEEEFKAIGETGLVTRNDTSELEMHRDSSALGHWTIMRTVLPSSVWEQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDD0</accession>
    <name>A0ABR3ZDD0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">triacylglycerol lipase</fullName>
            <ecNumber evidence="6">3.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Autophagy-related protein 15</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="primary">ATG15</name>
        <name evidence="22" type="ORF">Cpir12675_001952</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies. Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles. The intravacuolar membrane disintegration by ATG15 is critical to life span extension.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12044"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17855"/>
            <dbReference type="ChEBI" id="CHEBI:18035"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="EC" id="3.1.1.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Binds to both phosphatidylinositol (PI) and phosphatidylinositol 3,5-bisphosphate (PIP2).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endosome</location>
            <location evidence="3">Multivesicular body membrane</location>
            <topology evidence="3">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Prevacuolar compartment membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.3" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000034">
        <property type="protein sequence ID" value="KAL1898327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050805">
        <property type="entry name" value="ATG15_Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47175">
        <property type="entry name" value="LIPASE ATG15-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47175:SF2">
        <property type="entry name" value="LIPASE ATG15-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0072">Autophagy</keyword>
    <keyword evidence="8" id="KW-0967">Endosome</keyword>
    <keyword evidence="16" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 22" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="20" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="20">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046775414" description="triacylglycerol lipase" evidence="20">
        <location>
            <begin position="35"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="domain" description="Fungal lipase-type" evidence="21">
        <location>
            <begin position="276"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="510"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00024663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00029828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAL1898327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="657" mass="71294" checksum="6E61D7CBA3F3D04A" modified="2025-10-08" version="1">MMPPASPSRCTSATRVTAAVLLSFLAFSPAGVAGAHRAHGFGDNFHPDLVLPPGLDLPSETEPATDGPAPAQHTFTLRQIFHHGTHLHPHLHRRKDVFQTADNVFLAADAADGFDREPLPPLIVSSRQTRIERLADRRPAVVDAMVTQTRRYGQLEAMSPSAWTIDNISGPDVTNKQTVLSLALMCSDAYVEDDHQPDWDDVGKPFNRSADFGWEGDGLRGHIFADKSNSTVVIGLKGTSAALWDGQGTTTNDKINDNLFFSCCCGQQGQWTWHQVCDCATGTYTCNNTCVRKELQDENHYYTAVKELYTNVTELYPHANIWVTGHSLGGAVSSFLGLTYGLPTVTFEAVPDALPASRLGLPTPPGYMQSLLQTREMTGTYHFGHTADPVYIGTCNGATATCTYAGYAMESVCHTGYECVWDVVADKGWRVGIGTHKIRAVIRDVILKYDEVPQCKRTPECRDCGNWKMIESNGSETTSSSSSTSYMTFTRTRTETCKTPGWWGCLDETTTTSTNQPTSAPVTTTGSTTPTSTSTSTCKTPGWFGCKDPITPTSHLPSETSAPPITSTSTCHEPGWWGCRDPTTTTSATTATTTAPSTCRFPGRFFGCHSEPIGPPDPSSIPTATAAPESGRCIRRSWLGRCVAWNEDGILVLSDEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDF0</accession>
    <name>A0ABR3ZDF0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ferroxidase</fullName>
            <ecNumber evidence="3">1.16.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">YFH1</name>
        <name evidence="13" type="ORF">Cpir12675_001775</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11148"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.16.3.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the frataxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.16.3.1" evidence="3"/>
    <dbReference type="EMBL" id="JAWDJO010000030">
        <property type="protein sequence ID" value="KAL1898668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004322">
        <property type="term" value="F:ferroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.10">
        <property type="entry name" value="Frataxin/CyaY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017789">
        <property type="entry name" value="Frataxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002908">
        <property type="entry name" value="Frataxin/CyaY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036524">
        <property type="entry name" value="Frataxin/CyaY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020895">
        <property type="entry name" value="Frataxin_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03421">
        <property type="entry name" value="FeS_CyaY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03422">
        <property type="entry name" value="mito_frataxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16821">
        <property type="entry name" value="FRATAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16821:SF2">
        <property type="entry name" value="FRATAXIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01491">
        <property type="entry name" value="Frataxin_Cyay"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01219">
        <property type="entry name" value="Frataxin_Cyay"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55387">
        <property type="entry name" value="Frataxin/Nqo15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01344">
        <property type="entry name" value="FRATAXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50810">
        <property type="entry name" value="FRATAXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0409">Iron storage</keyword>
    <keyword evidence="6" id="KW-0410">Iron transport</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1898668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="180" mass="20045" checksum="2DD29D731EFE10D2" modified="2025-10-08" version="1">MSATTRSLRRLRLHRLSSPQLTGRTVLTRVSRQVHLGNQRTLSLSACQLGMPLTAPSAPVTSPSGLVPVPLSDQKYHELADEYLENVCTKYEDLQDMREDVDVEYAGGVLTIKFARVGTYVINKQPPNKQIWLSSPISGPKRYDFVADKSHPDGGNWVYLRDGSSMDGLLLAEMEMDVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDU5</accession>
    <name>A0ABR3ZDU5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SRP9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001957</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000034">
        <property type="protein sequence ID" value="KAL1898332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039914">
        <property type="entry name" value="SRP9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039432">
        <property type="entry name" value="SRP9_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12834">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12834:SF12">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05486">
        <property type="entry name" value="SRP9-21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRP9" evidence="2">
        <location>
            <begin position="8"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="144" mass="15295" checksum="6A6E55DE6C41E7B9" modified="2025-10-08" version="1">MAKSTYYKTSQDWLEQSAELLRARPSTTRITTKYSVKKPKTTSTSSASTTSGSGEPAKRAFLTLKTFDPSSGATLKYKTTKAAEVSRLVSALGMLGRDSAGLPPASLTNSSVEMKSEAVTAPTATDRKDEAPPTTGGKKKKGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZDV6</accession>
    <name>A0ABR3ZDV6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001973</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000034">
        <property type="protein sequence ID" value="KAL1898347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045342">
        <property type="entry name" value="Etd1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20162">
        <property type="entry name" value="Etd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="562"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="696"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="842"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1202"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="430"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="568"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="595"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="699"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="842"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1202"/>
            <end position="1217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1898347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1257" mass="137587" checksum="ACE8BB0E245CD353" modified="2025-10-08" version="1">MQAIPSLVGTSCAVAAASSGLVFGQALSDLDRSHTSYISRSASLEAQPRSTTGVSRLTRPFSQDCEPAFSRFSRLFVSEESESQSYSTSQASVQPQYQIQAKPSTPGNLHYHHRASSQSLKDSSHRQIQHQSSTISSVTISPSNLKSSRPSSRRYTLSKQLSFRRTLQQHQPVPPDQEPSLPHSRSQTPIIDEDCSTSVSSHGSWIRRLSLRPASQHGSPRTSSVFDTGYSARSAHISTPSPSHRSTYRPGSNSESPAGSPLSRNKLVKRPPSAHKNFEERSRRRRALSQLSGFHRPATSHQRSATLQSITSPIVADTPTFVQDQQHLRDSTNTAPPLSRIRPRANARWSSFFHAHTVMVNLRSGSNRFAESKHVSGRRVATVTRRMHVGESAANSPAFLLKSDQIYCRSAENTLFSFPQTGISHAQSFEERRSEVLRDEEAQAEPEHLQTPPRPSSSAKVPRRSLSMTLSSPGSWISKTGSLRRFKRNNEVTLDTFNDDGPNSQVFTGKRSSHYAAAATPLDTIEASILCDNTMMEPGNQDTPCEYDMATTYEDKCQEDLENEKDGATTSPTFSHGTQISGRQRKMPISRAATPASTHASSLQHPQAESMTPQASAVQPSRAQISIFSGSQASSDQSHGYFRRDRSSTIASSDIDGGDAASRDDDTDFRSERDVVFDSLRTHSSMLNRTVETPLESVFNDSPPGTTTGAFRHKRPSILPDPAWDAPSFLRDKNEDNLPTPVGLQPRLELVMDEYNPRLSMTDDLDDDWGDFDHSLAHGLSPPSVQGSMNMNSLSPNMRQALKGIGRNEGVDESARDSQFDQISERPLTNLFDWTESSIHVEGELDESRPRTVHGKHDTDTRGGRTSNRRSPLPAHIRSQSVPVVNDPSENAVANANPKFGTWGTGSKAASEDWGEDFEFGDEPTAIDANTADSELRSSFLMLVPASIQASQPSLRAHTGHIRELSLLVNDLKRLCRHGRELNLTSGSHRQLWEEAEGIIALASPDDEELESGVEAPDSPIDFPSDLSDQVLDDSFDEVDVSHPDGLENPDHNISSDNVSTNLVFARRRSVLMPDDDIFGGGGSSISSSPPRAVSVSSQWPLCGDETVISEFPQTPNSHTRTPQKHINGAVRSVAAAVHHSSTSDNGRGNDGKFHFDTTSLKTLVKQASDLRGRLACVLHEHDPISQSPVRKSAVNRASPAFTQVFNNPATSPSRLSTRPRAPSTLSISSSAVAEEPATALSEARDLGQRMQLVTLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEA4</accession>
    <name>A0ABR3ZEA4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CTLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_001643</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the proteasome-dependent degradation of fructose-1,6-bisphosphatase.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000027">
        <property type="protein sequence ID" value="KAL1898983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013144">
        <property type="entry name" value="CRA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024964">
        <property type="entry name" value="CTLH/CRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050618">
        <property type="entry name" value="Ubq-SigPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12864">
        <property type="entry name" value="RAN BINDING PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10607">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08513">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00757">
        <property type="entry name" value="CRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00668">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00667">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CTLH" evidence="2">
        <location>
            <begin position="56"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1898983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="226" mass="25575" checksum="87A61D5AD737BE09" modified="2025-10-08" version="1">MAVMTRSMEQRIDTLHPPKSEINAMILDYLTREGYADAAAKFCREADLDPQQPTEMIQERRDIQQAIRSGRVQHAIEALNDLDPEILDSNTDVHFSLLRLQLIEMIRDCSRKGDDPGCFLPAVQFAQENLASRAVEDPSLLKSLEKAMSLIVFPQAELTCELTSLLDPRLRQEVAESVNKAILSHQDKRGETVIRYLLGMRAWSQKMAQNSEIKLPESLQSGLDVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZEB0</accession>
    <name>A0ABR3ZEB0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Asteroid domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_001661</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asteroid family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000027">
        <property type="protein sequence ID" value="KAL1899001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026832">
        <property type="entry name" value="Asteroid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039436">
        <property type="entry name" value="Asteroid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15665">
        <property type="entry name" value="ASTEROID PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15665:SF1">
        <property type="entry name" value="PROTEIN ASTEROID HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12813">
        <property type="entry name" value="XPG_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Asteroid" evidence="3">
        <location>
            <begin position="135"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="529"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="541"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1899001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="571" mass="63665" checksum="3405F0A54CE809B1" modified="2025-10-08" version="1">MGVPRLRAKLLPYATKTTLNGSKIVIDGPALAYYLFYSCHQKATGLLSALDLVERLLAWLQVLKEFNVKIEAIYFDGFLPADKLQTRMKRHVERCKASREFFQAFSSGCPLSVACYSPKKPGISHFGSKIPTTLFLVPAVLEALLESSDYGDKVCVVPGEADTYCAAYAAKHENITVVSGDSDLIIHALGPGGGVVFFADMEVTDDALRCLRFEPGFIETQLSLPPKSMIQLAYQALNMPQANSRVIAKKCLNISHQERQYQRFAEPYLESVDLAMVSKYQGFFLGPPYLDPKLSETTLRYIEISFKDEKTQETETPYSFLPALVDSMLETSAWVPSTSIRQIAYSLLQIIRPSHIKSVNEFRRISQVNSQGVGVDVLSHKYLTRAIVNLTQVMVRFNDLSSSDFLMAMTLRLDIQNAVLAQRRPHSFKLVANASSINELQSTVSWALLHFSAQTQACAYSLRMIQQLLSFMSCNNAQESESASHMGRHLLRLPPPTGLPDLQGIQGFFLKLPGTPLLRDLCAEFEVDEPQVKSPKKQKAINKNSDTISQASMPKLKSPNSNNPFELLARD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZHQ6</accession>
    <name>A0ABR3ZHQ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NFACT RNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_001241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000018">
        <property type="protein sequence ID" value="KAL1899742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039730">
        <property type="entry name" value="Jlp2/Ccd25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13049:SF2">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13049">
        <property type="entry name" value="DUF814-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1899742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="178" mass="20861" checksum="C1D107AC488061FF" modified="2025-10-08" version="1">MVYYFTSKVVDPPANIYVGKDKFENEDLIAYGWNEDVCETSKGNKKDNITVIYTPWANLHKDGSMDTGQVSFKDARKVRRILVTTRENAIINRLNKTRVERLAPELDLAAEKDERLNELRKLDRIAAQARRKEELMLEKEYKEKKWQKEHAYDDFFSDTGMEASSNANRPEGWEDDFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZIC8</accession>
    <name>A0ABR3ZIC8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mitochondrial division protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_000938</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in mitochondrial fission. Acts as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat MDV1/CAF4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="8">
        <location>
            <begin position="205"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="775"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="817"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="858"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="909"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="943"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="984"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="1026"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="1098"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="1140"/>
            <end position="1181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00039789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00043913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1290" mass="142643" checksum="B0360120676953CE" modified="2025-10-08" version="1">MEAIGAATNVIAVIDLSVKVATLCVLYAKGVKNARNDINRLHDEVTDLHRISQHVQDLLNGPNRNKLESSQILDDALIRSRSQLTELLQTLDYEPPKKWHKMFSMRTLKWPFKREDVEKSIEELRENNQTISLALQIDQTRIISNVDNNVEHIGQDITQVGQTLFTLDQKNVLSKLPVAPGASFDSHEEEYNPTCLETTRVELLQEINDWAGNPDTKGLLWLCGMAGTGKSTISRTVCTQFEKSHNLGSSFFFKRGEANRGNLSKFFTTIASQLAAKHPVVAPHIKSAMEEEPNIFTKSSSVQFDSLIKQPLEKISLHSQQPPLLFVIDALDECDLDEDVRLAIKLFSSCTNEMRSKMKVLITSRPDLPIRLGFSDVEGSYQDVVLHEIPSSIINRDLRTFLEYRINMIKADYNRSVPPHRALELDWPGEDNIQTLVEMATPLFIFASTICRFLADRKCGNPNKQLHQVLEFKTESQASKLDATYLPILNRLINDDDLSTEEKHQVIKRFRKVVGSIVILASPLSTAALAKILNIPQDDIDDQLDLLHSVLSIPMSDNLPVRLLHLSFRDFLVNVDTQNKTPLWIDEKGTHEDMAANCLDVMHKYLHADICGLVKPGTARVSVNPETIQSHISSELKYACLYWAYHVKEAGTYLDGADGNDNRVYEFLQAHFLHWLEALSLIGNISDSLDIVKSLLSILQPTGNEMLHAFLQDASRFILANLSTLNAMPLQIYSSILIFTPKKSPVRQCFENQIAGWVSGLLVFQDDWHQYRQIMEGHKGGVKSVAFSHDCKHLASASVDSTVRLWNTSDGTCIQELKGQTKAINCVAFSPDGELIASSSNDGSVWVWQADGSVLHTIVPDGEAVASVAFSPDSKLIASGSFGGPVTLWNRDDGVCTQVLSGTEQEITTSVAFSPDGAILASGSIKGSVSLWNPHDGTRLHVLKAQEERISAIAFSSDSKYLASSSQDGTVCLWKVDGTLVLTLTGHLGPVSSVAISPNRKLIVSSSYDTKIQLWRFDDGARLQTLKGHMDDVSSLAFTSDSALIASSSMDGTVRLWPLDDTMFQPSGETEAEPSDRKYMVLPLAPKLLNNLDSIWGVEGHSSRVSAVAISPDETLVASGSYDTTVRVWRSDDSTCVQVFKGGESTVESVAFSPDGAFLASTYPNDGVLVWDVNTGACVYSREVEHDDIQSVRIDDSGESTVVYEGAPQPGFSHSDLEAARQPIAECVNDVGISSDGCWVLWQDTPILWLPARFRSYEGHESSSQARGRTVAIGCRSGRVVIFKLRDPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJ87</accession>
    <name>A0ABR3ZJ87_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000787</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="428" mass="46679" checksum="035989F959C06E3F" modified="2025-10-08" version="1">MSEARAPRPPLLKPRFYLHVDFGIDWIQKEATTASSSSSHHYEPSQPPSKSKAHSFFTSRARKNRKPEFPQRRTRSLDEIYPDPSDQPASLDLSTSAQPAIFPYPVLPLTPGDLNARDPLTGYYAPDESPTPGGFVEPMGSQQWEKGLNAQYYQPQHQQRSASSSRSPRHLPAASQDYSRIDSVADLSYPSNLVPGNQPQNLHLTPDPFQELFLSSALPSSPLGLMAEGRQKSPSHLLPSQRPPPPMDKKLPALPPNKSHGLHDSRDNGHSCHERHISALISPLSEYIPSPISPCGSRYAGSRMGSACSSPEISPLMQPAMLAHSNDNSGSLPALAPSIPPISTMPTASVSDYLSFKPSAQPHLQIRPVRSNTYPEDKSLTAMAALDEQQSPTMPVASNAAEMVALSSAMMTVDSGFEDKRWNWSAGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJK4</accession>
    <name>A0ABR3ZJK4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_000984</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000013">
        <property type="protein sequence ID" value="KAL1900402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051727">
        <property type="entry name" value="DnaJ_C3_Co-chaperones"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44140">
        <property type="entry name" value="LD25575P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44140:SF2">
        <property type="entry name" value="LD25575P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047483463" description="J domain-containing protein" evidence="6">
        <location>
            <begin position="23"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="34"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="68"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="7">
        <location>
            <begin position="405"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="463"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="465"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="517" mass="57197" checksum="018A51E8D7887F75" modified="2025-10-08" version="1">MHLRIPHLAVLTASAFAPSVYALSEHNIPSDLPVSSLLSSAQVHLSKGETSDALLYYDAAVSRDPSNYLTIFKRATTYLSLGRVNQATEDFNKVLTLKPGFEGAHIQLAKIKARNADWDGARGEYKSAHKTASSPEVVEMETAAKAAVSGMAAHERGDWATCVSDLSVSISVASRAASLREARYKCRAEKGELEEATADLQQLLHIRHSDTRPHQVIAALSFFAMDNMDAGMEQIRKCLISDPDSKVCMAQRRIMKDTQKSIEKTLKLIEAGRSSAVIKILVSTDAKPGLLAEVKTVIENLKKEDILPAGVSSQLYNRLIEHTCRAYYDSSSKKAENYCPDALANNENSLYGLLWEAKKSMDAEDFDGAVHKLTQANEAHPDQRDQIQRLLQKAQVALKRSKTKDYYKVLGVPNDADERLIKKSYRMRSKEHHPDKAVKRGVTKEEAEKKMAAINEAYEVLSNPELRRRFDQGDDPNDHSGNSGHPGGNPFDSFNFQGFPGGFSGGGQQFHFSGNFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZJV0</accession>
    <name>A0ABR3ZJV0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cpir12675_000900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000012">
        <property type="protein sequence ID" value="KAL1900434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051872">
        <property type="entry name" value="Cytochrome_b5/Flavoprotein_Rdt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46237:SF1">
        <property type="entry name" value="CYTOCHROME B5 REDUCTASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46237">
        <property type="entry name" value="CYTOCHROME B5 REDUCTASE 4 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="5">
        <location>
            <begin position="234"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="41"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="70"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="89"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="132"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="171"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1900434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="330" mass="34686" checksum="0108D1E6E1898845" modified="2025-10-08" version="1">MGYIGISLIVATAVLVLVRPPPWLRRQLFLLFHRAATTDTDVTQPHQHNSERTPATGDPDKLVKSLGGIDGRRPDPNVDADKDADVDQTTPKATATTPAGTIPSLSLSDDLTPSTITPSRSPNAPRAPPFAAPTAPITARAPPRLPSFPAMNSPQRASGPAPNRRPDGLMAPPTAGSSSNSGGSGLAPPPSHSRIPAKPSRKVILTPGHSPLDWARISGPNSDLRGLGGPSAPFLKVTPTMLKKMTGRRGKDAWMAIGGKVYNVSPYAKFHPGGVPELMRGAARDATQLFGEIHPWVNYENMLQACLVGILVEDGPTAGVDASSGMDEMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZK39</accession>
    <name>A0ABR3ZK39_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cpir12675_000799</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000010">
        <property type="protein sequence ID" value="KAL1900785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14705">
        <property type="entry name" value="bZIP_Zip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13044">
        <property type="entry name" value="ACTIVATING TRANSCRIPTION FACTOR ATF 4/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13044:SF14">
        <property type="entry name" value="CRYPTOCEPHAL, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="8">
        <location>
            <begin position="140"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="23"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="166"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="105"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1900785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="207" mass="22315" checksum="D31EE7EAD6DA9C46" modified="2025-10-08" version="1">MWDPYASTTQPTPYDPALAASDLFSSLAQPDPGAVASSSGGTEGPGIPALVQTFANAHQNPHTHPNSHPHPHPHSHTHAPSPIHDYTTAQTHATLPLSSFSPGDSTTMGLGAASTSSSSINTGGPSSSPIGSEQFTAEQKRLRNNSASARFRVKKKMQEKQLVQHTMESAEKLTQLQGKAQELERENKWLKNLVLEKSRKKRPEEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKB0</accession>
    <name>A0ABR3ZKB0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rab GTPase ypt31</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">YPT31</name>
        <name evidence="2" type="ORF">Cpir12675_000736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01868">
        <property type="entry name" value="Rab11_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1900860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="211" mass="23135" checksum="04DC089A5CB49CE2" modified="2025-10-08" version="1">MANDEYDFLFKVVLIGDSGVGKSNLLSRFTRNEFNLDSKSTIGVEFATRSIQVDSKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDISKHQTYENVTRWLKELRDHADANIVIMLVGNKSDLRHLRAVPTEEAKAFASENHLSFIETSALDASNVELAFQNILTEIYRIVSSKALDSGEGAQATIGAGTNISLSKPADDASTKSGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZKB5</accession>
    <name>A0ABR3ZKB5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Saccharopine dehydrogenase [NAD(+), L-lysine-forming]</fullName>
            <shortName evidence="13">SDH</shortName>
            <ecNumber evidence="4 13">1.5.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 13">Lysine--2-oxoglutarate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">LYS1</name>
        <name evidence="16" type="ORF">Cpir12675_001213</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>L-saccharopine + NAD(+) + H2O = L-lysine + 2-oxoglutarate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12440"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:57951"/>
            <dbReference type="EC" id="1.5.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 13">Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-lysine from L-alpha-aminoadipate (fungal route): step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the AlaDH/PNT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.7" evidence="4 13"/>
    <dbReference type="EMBL" id="JAWDJO010000017">
        <property type="protein sequence ID" value="KAL1899989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12188">
        <property type="entry name" value="SDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051168">
        <property type="entry name" value="AASS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027281">
        <property type="entry name" value="Lys1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133:SF23">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE [NAD(+), L-LYSINE-FORMING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018250">
        <property type="entry name" value="Saccharopine_DH_Lys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01002">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9 13" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="8 13" id="KW-0520">NAD</keyword>
    <keyword evidence="7 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal" evidence="15">
        <location>
            <begin position="6"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding" evidence="14">
        <location>
            <begin position="172"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR018250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAL1899989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="371" mass="40388" checksum="DCBA5B6E11B9E870" modified="2025-10-08" version="1">MSTTLHLRAETKPLEHRSALTPNTTKALIADGYTVNVERCSMRVFDDKEFEEAGATLVPTGSWTEAPADHIIIGLKELPEETFPLKHTHVQFAHCYKEQGGWKEVLARFPRGGGTLLDLEFLTHENGRRVAAFGYHAGFAGAAASLIDWAWQINNPGKSMPALTSYPIQDRLITDVKAALAEGSKKAGRQPRVIIIGALGRCGTGAVDMVMAAGIPAENILKWDIAETKAGGPFTEIVESDIFINCIYLAQKIPNFVDLLSLQSPKRKLTVICDVSADTTSPYNPVPVYNVATTFSNPTVPVTGLEGEPLTVIAIDHLPSLLPREASEAFSNDLLPHLLKLKEWKNDGVWARANALFESKVATLPAEALKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZL15</accession>
    <name>A0ABR3ZL15_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Geranylgeranyl transferase type-2 subunit alpha</fullName>
            <ecNumber evidence="6">2.5.1.60</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Geranylgeranyl transferase type II subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">BET4</name>
        <name evidence="8" type="ORF">Cpir12675_000748</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21240"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11537"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57533"/>
            <dbReference type="ChEBI" id="CHEBI:86021"/>
            <dbReference type="EC" id="2.5.1.60"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the protein prenyltransferase subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.60" evidence="6"/>
    <dbReference type="EMBL" id="JAWDJO010000009">
        <property type="protein sequence ID" value="KAL1900872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004663">
        <property type="term" value="F:Rab geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.120">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002088">
        <property type="entry name" value="Prenyl_trans_a"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129:SF2">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01239">
        <property type="entry name" value="PPTA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48439">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51147">
        <property type="entry name" value="PFTA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="84"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="84"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1900872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="404" mass="46686" checksum="330AB70A10654F81" modified="2025-10-08" version="1">MASHGIIRSVHVRTEQQRQEDLKKIDKYHKLEGEIRSRAKAQDFSPDTFDHTTRLIRLNPEYYTIWNVRRRCITSSLLSVLSAGSSSSMESPNSLPTLTTSPSTAAFSNSSSHETQCSPESPPTWKPGTTVDKPTAAHSQDLQILKTELLFTIPLLMNHPKCYWIWDHRVWALEQTIKRLPAKMARAIWEEELALDSKMLLRDCRNFHAWGYRLKLTERLESSELLGSSMAQAEFDYTTEKINTDLSNFSAWHRRATLIPRILIERAATSEDRKNLFNQELELVHNALNVGPEDQSLWYYHQFLMSNVMSSDPNKSFVPSLLSEDANAIIDEVLEFIQDLAEDYTDIKWIYEALLEYNPYKSKIQGRALLNDEKVELSRLIGKLEVLDPMRNGRWRDTRRSLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLE8</accession>
    <name>A0ABR3ZLE8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nem1-Spo7 phosphatase regulatory subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SPO7</name>
        <name evidence="3" type="ORF">Cpir12675_001018</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000014">
        <property type="protein sequence ID" value="KAL1900334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005605">
        <property type="entry name" value="Spo7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28249">
        <property type="entry name" value="SPORULATION-SPECIFIC PROTEIN SPO7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28249:SF1">
        <property type="entry name" value="SPORULATION-SPECIFIC PROTEIN SPO7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03907">
        <property type="entry name" value="Spo7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="170"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1900334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="461" mass="51773" checksum="AF2A6E6722D5E8D9" modified="2025-10-08" version="1">MADDFDSIVKGALQTQIDVKSVSGTTFIKTSPGTPTKPWDPLSTTPSSPPMIYLNLLVLEASLRAQYLELRARRRHHTFFLLLLSAWIVGFGYALFFAPREDGIGVGGSVYWGVEAGEKVCFMGGVITSILVWATGIWDRGIRWPRRWFNVSNRGLRGFNCKLVIIKRSWWAEMASTIGFFLTYGLFSHTASSSYRFVDAAILREVDRELYMTDVHSTVHNMGVPGLSAMCNDENGHEEDLAPAGDFVKLLLHAKPFSPSFREDWEIYRSEYWDKENERRAHIRAKLRARNRQYAKNRWGIFWWLPWHHAQTERHFARIASSRAAHLYSNGDANGALSHSAKGAQHHRSRSIRRGSVSSTRSLTPTRDSVSPAPMDGALLDRARRGSISLEMRRGKRLSVSSTTNAGGVLGSTSRKKPAFPETPSPLARESVLISDCDSKDEMDSSEKTKPAKRRPAITKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLG6</accession>
    <name>A0ABR3ZLG6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4484 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000502</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028115">
        <property type="entry name" value="DUF4484"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018626">
        <property type="entry name" value="LCHN/Anr2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053056">
        <property type="entry name" value="Lipid_Metab_Assoc_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28153:SF1">
        <property type="entry name" value="DUF4484 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28153">
        <property type="entry name" value="PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09804">
        <property type="entry name" value="DENND11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14831">
        <property type="entry name" value="DUF4484"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4484" evidence="2">
        <location>
            <begin position="404"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="452"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="513"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="363"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="457"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="525"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="613" mass="65632" checksum="E3A22210FA07E306" modified="2025-10-08" version="1">MSSSASTSASDPPPLSALFLIEFDVKAGYTIFWKRAVSEDIQLDDVVEFKSLPSGLHEVASDLVYFVHEGGYAGLSAFANAQVDDEAMRNARMIAVGVLVPLSYGRLGRAWQHTAEIQRLAQQLASDKTRISLLESYWKSHAATSPPDPNTTADTAVDASNPSAPLSSPSATTFATSTSLERHHPAHSLSRLLDSFGPLIFPLFRAALLRKRILISCHAPVHEVNDFVYDFSILSNIPSSVLDILPTNSPTQSLRPLFTVGVHDIPLLASNLEPLLVNTYEDSGSGWIACTTDSILACKQSLWDLLVTIPPPATCSQPDIPKKWPNLQTSAGTTIKATQRDLRRYMALKAGLSQIAASASVAAAPASPSSSARPARSSTNDDIPRPGSAITPPEASDASIAEIIEPMTWTALAYTGFMWWASAGEQHHSDELDEEAADAALLADLISPVPTPGTIPRYHDDPRHAGLEAPPPPKPGALETGQDTDTRVSLAIVAYFHRLTTQILSVAADVATSAAPPSGASNYAESRESQASEDGDRVDGESIVEHNDGEALLALDDDRDEGTRVGSHVLEAMGLDIWSVADTEFVNAALDMYFEQSVYVETKGVEVCGVRVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLK8</accession>
    <name>A0ABR3ZLK8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1901546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="307" mass="33605" checksum="7ED0492CE6030C06" modified="2025-10-08" version="1">MAPCPSQKKRRASKKLAKLLFVCQESPESPRFSKSTSQNKPTKPRPTEIKVRRRVKKFKSNIEKENSIAVAPDAVVETSGETQCAPVARKKPPNKRPVGYVPIAPALAPNTIPATPILEPATLDTFAQPLRPIFPPSEVHPSPVKNQNTTTGGIAPRFQDTYSDYVRLPDNQPTNEIPASCTSNVKSRLIESSYALHSLRTNESCAQPQHYLGKAVPDLAKEKPCSQQCQRSSDPAEISCSYTPARATETYSSTSDSSETHIGQIDSLLILSPASIRPKLALGMPVLSRAHTDKEIHLKMGISYITN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZLL1</accession>
    <name>A0ABR3ZLL1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">FMO1</name>
        <name evidence="6" type="ORF">Cpir12675_000466</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FMO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000005">
        <property type="protein sequence ID" value="KAL1901596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000960">
        <property type="entry name" value="Flavin_mOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000332">
        <property type="entry name" value="FMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAL1901596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="493" mass="53334" checksum="E4F3692D6FA5AB27" modified="2025-10-08" version="1">MASLLTALRGLLIKSHPEPTPVFDVKRVAIIGAGPCGTAVAKYLRAQNAFATIDIYERQSASACGGVWYYTPETAPAPYLPQTSPRTAPNDLVPGSAPPLYASAMYDDLHANIMGSLMQYTGCPFPASAKLFPSREIIYQYVLDYAAEVMDLVKFSHNVVRVDLASPGGRDQWTVHAEDDTTGGSMTTATYDAVVVANGHYSLSLVPEITGLAAFAIAHPGIISHSKQYRSNASFSGKKVVVVGNGPSGADIGRQIGQVAASPLYLSVRHATSPDRLEHIGAVEVPEITEFLPDIRGVRLADGVEIPNVDAVVFCSGYMFSLPFLPGLEEKLITTGRAVQGLYQHLFSIEHPTLAFPGLLQQAIPYAISEAQAAVLATVWSNAEKLPTKTEMQAWNDALVEERGENLHNMLKGTDGLYINTMHDWVGRSSVKKPPLWGEYQMWQRKLFIEAKLRFEKGGCTAMTLEDLGFKFPDLPGDLTTTSVAKGQGSTCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM36</accession>
    <name>A0ABR3ZM36_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cation-independent mannose-6-phosphate receptor CI-MPR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">MRL1</name>
        <name evidence="12" type="ORF">Cpir12675_000489</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000006">
        <property type="protein sequence ID" value="KAL1901257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.130.10">
        <property type="entry name" value="Mannose-6-phosphate receptor binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028927">
        <property type="entry name" value="Man-6-P_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009011">
        <property type="entry name" value="Man6P_isomerase_rcpt-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044865">
        <property type="entry name" value="MRH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15071:SF0">
        <property type="entry name" value="MANNOSE 6-PHOSPHATE RECEPTOR-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15071">
        <property type="entry name" value="MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02157">
        <property type="entry name" value="Man-6-P_recep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50911">
        <property type="entry name" value="Mannose 6-phosphate receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51914">
        <property type="entry name" value="MRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047011820" evidence="10">
        <location>
            <begin position="21"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="MRH" evidence="11">
        <location>
            <begin position="43"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAL1901257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="332" mass="35824" checksum="31B3849C7FB8FDD6" modified="2025-10-08" version="1">MARISLTSLLFALLSSGSLSLATANIASASTSSFPSSSTVAPAACTATSVSTLGGFFDLRPDIALPAPKDAPKVKGVRNTDYEARGWDYGYNFTLNVCSSVVAPVKDVVGIENSQWQNVSAYYTHEDMVYSLGQESMDLQSRGRKLVLQYKDGSPCESPSSSSSSSSATATTRRKSATISFLCASDPLVTSLVVTFVGADPDQCAYFFEARSSHACLSAEPQRPGSGSVGPGSVFTLIAIIAFMVYVLGGVFYNRTVAHARGWRQLPNYSLWASVWSVICDFTTIIVASCARFLPAPNSYGTAHYRRLARSPTRSREDENRLIDQLDEEWDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZM63</accession>
    <name>A0ABR3ZM63_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">THO complex subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_000249</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the THOC3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040132">
        <property type="entry name" value="Tex1/THOC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22839:SF0">
        <property type="entry name" value="THO COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22839">
        <property type="entry name" value="THO COMPLEX SUBUNIT 3 THO3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="70"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="206"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00046343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1901741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="326" mass="35443" checksum="298A025B0C3878C8" modified="2025-10-08" version="1">MSNTVRSRQMSGRSRGTHLVLPSRLAPRTKPFESVSFASNKSVNGEATNYYSNSAIGNPDRPNARFSTELKGHAAPIEKVAFNPVKQAELCSVSNDGTVKLWDVRNNLCVGEFKGLGEAFTLAWAPDGSSLIVGNKTDKLFIIQPGQSTPVASYQQSTQTNQIAFCWSGKKAFVTTGDGKTRILSYPDLKPLLLNEFDEPPSEFKLSGHTASCLTTALHPAARYLATGGSESLISLWDTKDWICQRTLAGMTGPVRSLSFSFDGSYISAGSEDGKGVRIWHTESGDEVHVIDTKDTASVVAWAPLHYRLAFNDHGSLHIASVSERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZN17</accession>
    <name>A0ABR3ZN17_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Translation factor guf1 mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">GUF1_2</name>
        <name evidence="11" type="ORF">Cpir12675_000195</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.n1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion inner membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the GTP-binding elongation factor family. LepA subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03699">
        <property type="entry name" value="EF4_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16260">
        <property type="entry name" value="EF4_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01890">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03709">
        <property type="entry name" value="lepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2570">
        <property type="entry name" value="Elongation factor 4, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00071">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006297">
        <property type="entry name" value="EF-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038363">
        <property type="entry name" value="LepA_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013842">
        <property type="entry name" value="LepA_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035654">
        <property type="entry name" value="LepA_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01393">
        <property type="entry name" value="lepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512:SF7">
        <property type="entry name" value="TRANSLATION FACTOR GUF1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512">
        <property type="entry name" value="TRANSLATION FACTOR GUF1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06421">
        <property type="entry name" value="LepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="2 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="10">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="72"/>
            <end position="76"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="126"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1902088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="596" mass="66588" checksum="522A108F4E7039EE" modified="2025-10-08" version="1">MDRCRNTHIDHGKSTLSDRLLEYTGTILANADNKQILDKLDVERERGITVKAQTCTMIYNYKGLDYLLHLVDTPGHVDFRAEVTRSYASCGGALLLVDASQGIQAQTVSNFHLAFAQDLALIPVINKIDMPSADLLRVLDQIENTFELDRKSAVLVSAKTGKNVAAVLPQVIEQIPNPVGDANAPLRLLLVDSWYDTFRGVVCLVHLFDGTVKTGDKLISMGTGVHYTVGEVGIQYPNAFPQSMLRAGQVGYLYFNPGMKRIQDAKLGDTFTFAGKEDTVEPYPGFEEPKPMVFVAAFPVDQSDHHKLAESIGQLVLNDRSVTLQKDHSEALGAGWRLGFLGSLHCSVFQDRLRQEHGASVIITEPTVPTKITWPDGKTEIIENPTEFPDNSMHLKMGTLQEPYVTTTMTLPEEYLGRVIDLCESNRGEQKSIEFFHSTQVILKYDMPAQQLVDDLFGKLKSATKGYATLDYEDAGWRESNLVKLQLLVNKAPVDAVCRIVHHSQCERIGRQWVTKFKEHVDRQMFEVVIQAAAGNRIVARETLKPFRKDVLAKLHASDITRRKKLLEKQKAGRKRLRAVGNVVIDQAAFQSFLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZND6</accession>
    <name>A0ABR3ZND6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SET domain-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SET3</name>
        <name evidence="7" type="ORF">Cpir12675_000108</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46462">
        <property type="entry name" value="UPSET, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46462:SF3">
        <property type="entry name" value="UPSET, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SET" evidence="6">
        <location>
            <begin position="286"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="118"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="517"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="585"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="917"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="126"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="151"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="179"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="517"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="534"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="615"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="646"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="668"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="681"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="694"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="918"/>
            <end position="933"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1902208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="979" mass="106841" checksum="BA862FF99154F7E3" modified="2025-10-08" version="1">MIEKHASLSTQPPVHHNHPIAGTWATPSKPLVKTEPESIEDEPYTIKCICNVSEDDGNTIYCENCETWQHIDCFYPDNREEALNENFAHSCEDCKPRILDHERAVERMKKFRAGILEEDEEESARHGKKTKRQMSKTSKKKPKPGDILLVNGSNTSSGSEVLKPSSTAAAVDSHFNNHQTHHHNHKKSKSSHKISSQQPPSTHFDKHSPSYAKLPSPASTPPDLPADFELHNYSTGLLSLYESDLQVVQNNSFADIETSRTMTNWLRDPKTLLSQTNQHFKDVFQPSLASSISRNKDIYVGQMKSLTVRATDLRIQYLATRAPIAKDSPIIELNGQVGLQISYCQAAHNNWGELCTPLPFVFFHPLLPLYIDTRKEGSDARYVRRSCKPNTTLETYLSGSQYHFWLVSDRYIGADEQITLPWDFRLPKEVLSRVLTLLGLNDDASSRQQEPEMDAAEYQNHAAWLYRVLTEYGGCACDLGDNCAFKRFHRNFLAKTMQRSSINPSSTLQVITNAATSSTTAASASTPATNSIPPKKKAARKSKSHVVSPTSIVPLADSRASSEVRLDDPITIATIADSDIRSTLAPGVRSKASSRERSPTRPIASFDQTGILTEPTDRDKRKVAMLEDTFRRMEQQPPKKKKRVTSDGSQSSAISKASKARSEKSSSNVTYSDAGTMSGKSPSPASAAFPAPSRHSTSRQTSAVPHSRQTSLAPSLVAIQSTTSYTDASTQTDPNEDDFFALPPPPPSRPIRRVVSLAQRLLNARKSQLAETARRASFSGGSVGMLSTSSINTNSTRQKRLSEASNLAISEDHLTIDIPNQPPRISDSAVCNIDAQENAVAQRPVDLRVQFPPPLLTGPNTLGVPSTTTTVPLSATSLVQSPFASSLHNPFGGAVSPVNPSPVKKKLSLSDYTKSRANKSAAAAASHKTIPASKLASADEAIGEEAIMAHREEGSSLSNAGVVSVMSSTAAASSVSENT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNP2</accession>
    <name>A0ABR3ZNP2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sacsin/Nov domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000397</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022155">
        <property type="entry name" value="DUF3684"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058210">
        <property type="entry name" value="SACS/Nov_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF047352">
        <property type="entry name" value="P_loop_sacsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47839">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G04830)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47839:SF1">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G04830)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12449">
        <property type="entry name" value="DUF3684"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25794">
        <property type="entry name" value="SACS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sacsin/Nov" evidence="2">
        <location>
            <begin position="27"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1412"/>
            <end position="1475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1491"/>
            <end position="1541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1747"/>
            <end position="1781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1419"/>
            <end position="1430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1455"/>
            <end position="1472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1501"/>
            <end position="1529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1747"/>
            <end position="1756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1768"/>
            <end position="1781"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1781" mass="197821" checksum="8F755682D02DEFA2" modified="2025-10-08" version="1">MDYSRLRAAALQGAEDEEAVTVDTRALIDKVLARYSGEWTTLRELIQNAADAQATKVTIRFETIPSISVPLPSNPTLSDILKHTITNHTLKRLVVQNDGVPFTNTDWGRLKRIAEGNPDETKIGAFGVGFYSVFADCEEPFVSSGAEAMAFYWKGNALFTKKSKLPEDQASKYTTFVLDYRNTTTPLPNALSVAQFMATSLTFVALERLEFFIDDYRLLDLHKKSSPSMSVSIPRDLVTRTKEGIMNVVSVDRTSTQIDARYMAAVSSKPKATALAKVTETFGGPIAENQFIRSFFSRLTSSSSSSTQKPKAVTTEEASATQKSLTDDITTVHTSTIFLRVTAAKIQTKVTASFSTELERATKKPPPKVAKLAILTSTYDETKASESSSAAKEIADVFASVLPSKKPGGRIFIGFPTMQTTGAGLHISAPSVIPTVEREAIDLNARWVRTWNIEMLRAAGIIARLSFLDDMNTLDQAFKGSLPQKIKNMSEHVAKFMPEALHILKTYSFEDSTPNSQVSQIIDESFWTSFKRPSVDLFSSRGVLPTEKIRIPNQELSRFVDDIPVVPEPMKDNEFVKKLISFGLIYGITLQDVQKALETKALDKAQVSYFLKWMTQGVLSGKIDHRNKVSLLEVAVASISDGEPAQGAIITLGAIRNFLSTNRIPAGMPLPPSTLPFAFTHSLTSIELDALGWEPLEIITWVRFLIEAAPSSPEEQNILKSAKFAVSALTVISKNWENLTNADRTLLTELLKRYPVIPTKTGMKKPTESFFPNVKVFDDLPVIQGCTSLKEKFLVSIGVRKTVDLETIFGRLLSPTAEGDKKWSHVELIRYLASVKDDIPAEDMRRLKGSRIVPAELPETDSKATSSTPTINTLHRVSDLFEPVDTFRDLGFAVIQWPGNLRPGSPENRFLAALGMRTIPTVPELVSLMSSNNAALHDKAMKYYISNFAINGYSAYDLSSTSKGFLPIEGDSKTLVAPKGCFTNEAAAVMGFKILRRHLHPYAIQLGVNRDPPLIDCIKYLVQNPPRESKQAATLFSYFAMRLNELREPFLSNLKQAHIVPVSKGRLIAPRDCYLGGSSQYSDIFDFVDFGAEANRFLYHCGAKNEPTRAELATFACDEPARLLSVLQAEKYLSLLRNFAENAGELQGDRALWKKMRSSAFLLGWQQISSGKEADDYDEDVAPMKQYKLGSSADIVIPDDFIMYRIFKTELICAPEEDILEFFYSSLGCSKLRACVQEDLRIGQLAAKQEIAQRLHKHVVERSKIFLYEYTSDKRVAIRHDAKWLEKHLSVAVVQSVSLRRTLNRGRPITHAEKRSAASANTSTGCTLYVAEGGNPDMYQIGQALCQILLHKQNQQAYIFFEPFLTLDLLGLKQRGYNVDRILRAKAAEARIAEQERQQALEREQERIRERAEEWKRSQQQQQQQQQQLQALGGAAPRGPQMPGGFDDDTGDSNPFPHQPETQQPETQQPQPLAEKKSRGLFSTLSRHLGFEQNSDDEDSSISNKQVSASPSPRPTNTGDSSSGNTNIENMPGGPDEGKALNPAALQQNLLNAVQSTRAHGSNQLQTPAWAGNIQEQTTYCDSGSGHDLTIAAESSKGMKVYMDRKIPSDTVSKILVTHNSAINTFADLLLDIAGVYTLSAQVMHIYYDQSGPTIAFNLNGSIFFNLRYFLQLHWADIQPGCVMLKKNEVVFWWWVVLAHELSHNLIKHHGASHTYYTQAFMQQYHSALMAKLAQVSTQSQIQPSTQARVQAQAQLGESLPPPPAYTPTPTAQRAPTSLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZNY4</accession>
    <name>A0ABR3ZNY4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Deoxyribose-phosphate aldolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_000294</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class IV-like SAM-binding methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000003">
        <property type="protein sequence ID" value="KAL1901785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18086">
        <property type="entry name" value="HsC9orf114-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003750">
        <property type="entry name" value="Put_MeTrfase-C9orf114-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12150">
        <property type="entry name" value="CLASS IV SAM-BINDING METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12150:SF13">
        <property type="entry name" value="METHYLTRANSFERASE C9ORF114-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02598">
        <property type="entry name" value="Methyltrn_RNA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1901785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="333" mass="36534" checksum="FCCFE27F0BB44AFB" modified="2025-10-08" version="1">MDRSLKRSKISHDGAGEFPSKPTSRFTPIESGRSWTVSVALPGSVIEDAHTTDQQVALPGRLGRALALHNIDEVILYDDTQASKRPAHIDPKSYTADTDPCHFLSHVLSYLETPPFMRKALFPLHQNLRLASKLPSLDVPHHPHPAEWIPYREGVTLSRKSKTGGTLVEVGLKDPVSLPDAIPPNTRVTVYMDTPTSPARAIHPADPRTEGGYYWGFSIRRAKGIGAVFTESPYEEGYDVSIGTSERGRPIHRSVPSGSLDFKHLLIVFGGPKGIEYAVSNDEDLGGLEVTGSKARELFDHWVNVLPGMGSRNMRTDEALFIGLTSLGSLWAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZP73</accession>
    <name>A0ABR3ZP73_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_000323</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat ESC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000004">
        <property type="protein sequence ID" value="KAL1901633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051243">
        <property type="entry name" value="PcG_WD-repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10253">
        <property type="entry name" value="POLYCOMB PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="52"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="101"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1901633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="442" mass="49015" checksum="CF369AAD6CB6E43E" modified="2025-10-08" version="1">MAGAPGRRHTLDSANCCCAWALDENDDPVICVAGTNAVIKVYTPDGTLARTLVGHGGEINALQTWPADPHLVASASEDVTIRMWSLNAAFKEAPCVCIYGSDTHCDDLLTIAFHKTGKWLLSAGKDMVVALWAVPDFPASPGPIVKQILAPQFSSSEIHNAIIDCMAFWGDVIVSRDCHEGGEIVVWRIEGFSSSNPLPADAVVPFSHEPDSFSRSAFASSVHSNAGPFLWHRLFKLAAPLCDTQFFMRFGFFSSPEDPPHLSDAIFGFCDANSLTSFWNFRHIIQYCDYFRALQDAAAEKAVCKASGTKWKPETPGYPLGVKRPSWLSPIPNMNTARTKASSSLSRKKRDSQSLDWLNKDHVNFLEQFYSYETATQWERMYDVSNPLRPLQPHWQCSIKGQARIGRQVAWSPSGQWCIVAMNRNTACFMERVPVESSEDTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZPP4</accession>
    <name>A0ABR3ZPP4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Membrane protein C24H6.13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Cpir12675_000173</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CSC1 (TC 1.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000002">
        <property type="protein sequence ID" value="KAL1902066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032880">
        <property type="entry name" value="CSC1/OSCA1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022257">
        <property type="entry name" value="PHM7_ext"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF53">
        <property type="entry name" value="DUF221 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12621">
        <property type="entry name" value="PHM7_ext"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13967">
        <property type="entry name" value="RSN1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="601"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="650"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="699"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="740"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="805"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="852"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="880"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like N-terminal transmembrane" evidence="11">
        <location>
            <begin position="42"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="12">
        <location>
            <begin position="214"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="9">
        <location>
            <begin position="599"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="domain" description="10TM putative phosphate transporter extracellular tail" evidence="10">
        <location>
            <begin position="1034"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="310"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="379"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="310"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="379"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAL1902066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1134" mass="126161" checksum="ECF5761955AF616D" modified="2025-10-08" version="1">MDSLTNSSSDPRLNSATANSTGGTLSKISVSGTSKSSASASALISTLIPVIVYSALCLSIFWLLRHKFPRVYSPRTILTSFLPQERSQPLPGHLFKWVTAFFKVEDTFALQHISLDAYFFLRFLKVLSGLCFVGVCITWPILLPIHARGGSGLKQLDSLTIGNVTEKKTFVVHALVCWLYFTIVLYTIYRECIFYINLRNAYMFSPYQAQRLSSRTVLFTSVPPRYRDPARLRKLFGDSVRNVWIPKDTSDLEKLVEEREQTALRLEKAEIVLIKLANRLRKKAMGQEPPSEAEQLDPQFQPDFVLGEKLSTQSEVPSSSSPETLSDSHVPGNKDIFVGSSASPPIHDQHIPPKPTITSDFQQSKVDIQEQIIALDALQQESSNDSTINGTGSKIASLSSPPPSEAAPASPIKSECAIDDEKVPYVLTEAPEPISTLTKLQADDEGKVWCEVQQDTQTQPEANNVPATKDHSIDVEVAHPRLPDVNGSVAAQWVPAEMRPAHRPLANFFRRVDTIKWTRKRIRIINPQIRKMRKMLLQGEGKPLASAFVEFTNQADAEKAYQTLTHHLPSHMSSRYIGVTPDEIVWTSLNLTWLSLLIRKFGIAGATFVGIIFWSIPSAFVGAISNVEALAKYVTFLDFVLKFPEFVKGIIQGFLPAIMLSLLMAIVPYLLRGAARTAGVPSLSLIELFVQESYFPFQVVQVFLITTISSAASAALMEVVKSPFSAPSLLSENLPKASNFYISYILVQCLAAGAGAMVHLVDIFRHQILARNMDYPRSAFRVWHQVRPVHWGAIFPVFTNMGVIAFSYCCIAPVIMIFASCGIFVIYLVYRYNLMFTYNSNINCRGLVYPNALLQLLTGLYLAEICMIGLLALRVALVPMVMMVMFLIFTAMCHVSMSAAIRPLLYNLPQSLAVESHELAHGGNFNIGSDDVIPDDVTRTANGDTNIRLKAPSADVDDGYIIPKHSSDVDHEEIASRGMEGADRFVTSIFSIGKLKLSEVTQALDKTPIGPVATYLNRWISPPRDMEPGFVMRWLHPEVFDDFAAMQKLLPPELPNPTLTYPEDYSSKAYWPPAMSAPPMRLWIPRDEAGVSKQEVEHTSKVVSISDEGAELLPNGRIRADVEKAPFFEERIVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3ZQ51</accession>
    <name>A0ABR3ZQ51_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_000116</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000001">
        <property type="protein sequence ID" value="KAL1902216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="386"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="812"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="984"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1017"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="821"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="875"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="986"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1092"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1128"/>
            <end position="1137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1902216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1137" mass="124219" checksum="06A8BECE890BE931" modified="2025-10-08" version="1">MPHDQFMTHETHEPPFLQPTTSAEPLPLFRPPPPPPPATQTASSKPTATLISTTISDAPTSAFVTAPPSPASRWWDASVDYNAPHAGPEPDPPLAPMGSCDAFFRVFLDNNTTTASRPDSTAVVPFSGTAASAAPLASGPASALGPTQPSLNLPSGQCNFVDLTLGGNGAKCGCRRFYSSCDALKSEPTEFCMCMHHACFHDHSPSNASTNAPAQQLDTPASYFPPPPLLPPHSQLQSHIQPSIKTPRIAQSPLQDISSRFSQVTASRPPMLPPSHRPSTSASHAACLHPPPPPPPRPLIDPRNPKTQSTSIPDTLGWNSLGTAQLCSKNDSISTNIAPARQPSSQLSTTTTSSSFFLPFGGKGAHLIGALGTKAREPLRDKLHNKDETTVEQSSILKPKRPTCDSMATTCSDSEVAEPAKSLSKTFKRPSNKNISSTESPSKENPNMDLKNLTDMVNSYEHRLDRLENASVITSMHEECNERHESLDLRLYDLETRVEDVEKLVNDNSFKGGQDSMSSDGYGRADLVSRIEALQAQINLLQNTVPSIWQPWEVDVVFLPFALHKIWLPSHEFKINSSLDSLPGTDSWISQPPGAYSLSSSHRPQSPFCQDWGGDEDGQDWLLPRAYRIDSLLDKRLRSRGCIRRISVKGPDARSVQIAINASFAGLLGSISAQRKSQLSLTRTSKFMGLQQDWVPLRKIHKDSRLRFLTPAELITPATWDVVFLKSVLMKSSQPRLFITQPEAYVQDHIAFDLGWTWQRLRELSRFYSEDSESQEVGEADALEECWTWNDLLDGQSTEAYKPWLRDSLISPASHRNPAHSQASRYASSPLSSSRGQTPNKVVKAPSRTMLGRTASVPPVRHVPSYSFPSASAPDNRRRMTCHDGHSQSPIRTSFARRRPTRSPSNRAHPTPRWSSGPPSPRPFALNTPTPDGTRAVSSSSSKGSRATAFNYATPHSNTTAPAGANAKSDADTDIARANDGDTFMTEDSFSINGDSDSGPILHNHHDNLRQALQSHAASFHGHSPFHSQHPKHEFASDDPASWHQLPEDEPWPGIEDHVSACNDADGQCQGQNKDEGQDQSQDHAIIFRQPGSKSANGLGSTSDASSSQPSEYPSIHPNHGGFHIHEDEDEDENMIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YDI6</accession>
    <name>A0ABR3YDI6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cpir12675_006911</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000420">
        <property type="protein sequence ID" value="KAL1886031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051575">
        <property type="entry name" value="Myb-like_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621:SF1">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="400"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="114"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="167"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="191"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="264"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1886031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="459" mass="50838" checksum="34B2102D41C6AC74" modified="2025-10-08" version="1" fragment="single">SAVFFSGVLAVPFRPESIDFLTGDAPNSTTASLQSLLPSTLPHILPQPATQHLPVSLQSQQQTQTQTPGRASTSQILSIQSPAAAQSGGSLWRTGCVDNTLANYRVSDYSVDYSTQHSPAGGPEHSQSQHVYEPAAPAHHHQQQHQQQQQQQQQQQHQQTPNTQHHQPQHHHAHQQHQQHQQHQQHRPSLHHPSSASSSILDPPDQHHTGATTHLPGMAQHHHQHTQSQVMMDPSQLAPRHMAHPHSYSAGMFPSLGPGPTHSSTHRPHSGPMKRPRPDDLDLSGIPDLDQGDLDMQQTPLSYGPPGSQPTHHHHRLPETGPPTKMMRRDETSGGAPSVVGQAGMPAPALRPRGPKLKFTPEDDQLLIDLKENKNLTWKQIADFFPGRSSGTLQVRYCTKLKAKTTQWTEETDQKLRNALQDYENEKWRIVANKVGTGFTPVACRERAAQMQFTAEPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFI4</accession>
    <name>A0ABR3YFI4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ethionine resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ERC1</name>
        <name evidence="7" type="ORF">Cpir12675_006711</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000358">
        <property type="protein sequence ID" value="KAL1887065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13132">
        <property type="entry name" value="MATE_eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045069">
        <property type="entry name" value="MATE_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="322"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="393"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="422"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAL1887065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="473" mass="50460" checksum="5786C5A11B69C147" modified="2025-10-08" version="1">MASLSASSDHALWLSEASLQIKAAIPVILAYTLQNSLQTVSVLVVGRLSAEALATAAFSYMFAMSTAWLVALGGTTALDTLASSSFTAAAVGTADRSGLGVLLQRGLVVLSGFYALVALLWWHSETVFRWLGQEEFICVQSAAFLRCLIPGGLGYVWFESLKKYLQAQAIYRPGTYVLLVTSPLNALLNYLFIHRLGFGLYGAPIATGISYWLSFLLLAAYAAFVRGSECWGGLDLRRACSHTAPFARLALLGVMHVGTEWWAFEIVALVSGRLGTVPLAAQSVIMTADQVINTVPFGLGVATSSRLGNLLGSRDHVGAKRAAHTGAMLSVAAGVVILAALMASRHTFGRLFNDDERVIRLVSDVMPYVALFQIADGLNGSCGGALRGMGRQWVGAVINMLSYYCGALPAGIFLAFHGWGLVGLWIGQCVALYLVGTFEWVIVGMSNWEQEVANAMQRLEDGGVSNIAQDAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YFV9</accession>
    <name>A0ABR3YFV9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_006650</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000342">
        <property type="protein sequence ID" value="KAL1887199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF43">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G01850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="18"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="123"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="235"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="135"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="157"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="245"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="265"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="807" mass="90985" checksum="A54FF39E4D3F5400" modified="2025-10-08" version="1">MPRPKKPGAEPKKRSRTGCWPCKGRKVKCGEERPRCTNCERVGEKCDYSIRLNWDSRRGKKTPDFNNESNTGMALLSNNHEFTIVNHPAMGNMKQIQPAPPKSNSISMNSSDALNLVPAKSLSQPVLSGSRRNKFPSQQGSSLRSSPEHLSNSLSSITNFNAPMQLSDSPVNPHSSDVSPSNRPSFENCSPQPFLGGSMFSTFQANINVPDAKYVSPQSSQLFLNSLQLPTAFNHPERFYPRPRQPSSNSSQSPSLLEHFKDNSPRTPAQSSPCSEDDSHLSRLVDFKRSPPLQSPVPRLDVNSLLSDNPIEYPQRAFPISVKWSDIGKWDEAKLATTTSDDTFFFGFDLGRKDRDLMSNDDANAILSEIPVNGEITAESPPNSQDIRVSSAWCPMDTKDVDYYRDPIRIVIPRKYMPLPPFIIFLTTQLKVGLLMPYDDIERNPYRNVLPEIAVAEPHLLRLLLAYSASHRARLLGHKEPELRMAQWILEVIPQVKFGLNPDNSKASIANLASSIMLASLEVISPNAFGSQISWQNHLITARYLMMNRNLWRSNKNTKEGECCAFLWSWFVYLDLLGSLSGGPWSHDISSNWVGYYDSIGDDQGDMDEIDCIMGFTIRCVRLLARVSDLCRRSDSQRLNSERAINHDWRPDQETLARAERLDDALRESMGRNGHICDHVRPGVDRSSLAEMFATNEAFHWAGLVHLHQRALGKPKEHNDVAYAVNKIIQCMDKVRDSGTGEMGILFPMFTAGCNTTRGEDRQKIDNRFNNIEAHGMKQVSKARKLLKKVWDLNQPWETLLKDEFIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YG98</accession>
    <name>A0ABR3YG98_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">tRNA dimethylallyltransferase</fullName>
            <ecNumber evidence="5 6">2.5.1.75</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">tit1</name>
        <name evidence="9" type="ORF">Cpir12675_006582</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>adenosine(37) in tRNA + dimethylallyl diphosphate = N(6)-dimethylallyladenosine(37) in tRNA + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:26482"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10375"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74415"/>
            <dbReference type="EC" id="2.5.1.75"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 7">Belongs to the IPP transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.75" evidence="5 6"/>
    <dbReference type="EMBL" id="JAWDJO010000328">
        <property type="protein sequence ID" value="KAL1887349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052381">
        <property type="term" value="F:tRNA dimethylallyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00185">
        <property type="entry name" value="IPP_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039657">
        <property type="entry name" value="Dimethylallyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030666">
        <property type="entry name" value="IPP_transferase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018022">
        <property type="entry name" value="IPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00174">
        <property type="entry name" value="miaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11088">
        <property type="entry name" value="TRNA DIMETHYLALLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11088:SF89">
        <property type="entry name" value="TRNA DIMETHYLALLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01715">
        <property type="entry name" value="IPPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039110">
        <property type="entry name" value="IPP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="394"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR039110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAL1887349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="461" mass="52063" checksum="A004DAD293A47848" modified="2025-10-08" version="1">MRPTDPLIVIMGSTGTGKSDLAVELAIRFGGEIINADAMQMYSGLPVVTNQITEAERRGVPHYLLAHISLDQETWAVGDWKHEAQALIGDIRSRGKLPIVVGGTHYYLNGLLFEDILVAGDTDTTSDFPILDEPTEVLLAKLREVDPVMADRWHHNDRRKIRRSLEIFLRMGRKASDIYAEQQLRQQSFTFPLDAQKQPGPWETLLFWVYSEPETLKTRLDKRVDKMEHAGLMTEIQEMFSYLAAKNASGITVDMTRGIWQTIGFKEFRAYLELVNSDSQIEPDVFETLKAQALEDMKTATRQYARSQIRWIRRKLIPLLKEEPGALAKLFLVDSTDVSTYAQTVVEPASTITRAFLQGEPLPAPEEVSDVAREELRAAGEPVKPRAIPIKRMCELCHMTLVSEDQWQKHLKSRRHHRVAKNAKKRALAIIPNQPAQDVLAVDEAIADMEGLEADSANEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGU4</accession>
    <name>A0ABR3YGU4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">beta-glucosidase</fullName>
            <ecNumber evidence="9">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">BGL1</name>
        <name evidence="11" type="ORF">Cpir12675_006713</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="9"/>
    <dbReference type="EMBL" id="JAWDJO010000358">
        <property type="protein sequence ID" value="KAL1887067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011658">
        <property type="entry name" value="PA14_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF27">
        <property type="entry name" value="BETA-GLUCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07691">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00758">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 9 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PA14" evidence="10">
        <location>
            <begin position="394"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1887067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="830" mass="90576" checksum="EA68E4892DFE8A9B" modified="2025-10-08" version="1">MANIDVEDVLNKLTLTDKADLLAGIDIWHTKPIPKHGVPSLRFSDGPNGIRGTKFFNSVPAACLPCGTSLGSTFNTELLERAGRKMGEEAKLKGAHVVLGPTINIQRSPLGGRGFESFSEDPTLSGLGAAALVKGIQSTGVQATAKHFVCNDQEHKRNAANSIVSGRALREIYAMPFQLLVRDAEPGAFMTGYNGVNGTFCSENKELLETMLRQEWGFSGLVMSDWYGTYSTTDAALAGLDIEMPGPPRFRGEALKFNVATNKVPEFVVDERARTVLELIKRCAASGIPENAPEREGNTPETAALLREMGIEGTVLLKNEDSLLPLKKDKKTLVVGPNAKLAMYHGGGSAALRSYYAITPYEGISAKLTQKPEFVLGAYSHLMLPLLSNVTTADGKPGMSMKVYREPPTAIMRELVEYVHLEKSDMLLVDYNNKRLSDTWFANIEGTLVADEDCTFELSLIVCGTAKLFVNGDMVIDNATKQVPSDYYFSYGTAEEKGTYKFRRGETYAIKVEFGSTPTSPLAFERVLLRGGALRIGGCKIIDSQQEIIRAADAARDAEQVVICLGLNADWETEGSDRETMKLPGHLDALVSAVAAANPSVVIVNQSGTPVEMPWIASVKAVVQAWYGGNETGNVIADVLFGDANPSGKLPLSWPIRGQDNPAFLNIRCEAGRTLYGEDVYVGYRYYEFAERQVLFPFGHGLSYTTFKLSDMEVAEADGVLTVAVTVSNTGKKPGSETIQTYVKPPPTKVTRPIKELKGFAKVRLDAGETKRITITAQTKYATSYWCEERKKFAAEKGRYEVVVDTSSETTANAMRGVFTVDKTYWWTGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGV2</accession>
    <name>A0ABR3YGV2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cpir12675_006504</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000311">
        <property type="protein sequence ID" value="KAL1887556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF23">
        <property type="entry name" value="THIAMINE REPRESSIBLE GENES REGULATORY PROTEIN THI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="109"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="621"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="774"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="55"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="621"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="774"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="827"/>
            <end position="836"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAL1887556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="914" mass="99012" checksum="9B7A52A55274DE9C" modified="2025-10-08" version="1">MDASQQSAASASGQPVITTVTVPSGTPSTGPGGPELGPGMAAASGTSPDHMRTTADGNASGSGIGNTANGGAVPASTGYQRGGASVNGGVPKRRPRRVDERDRKRAVRACDECRRQKEKCEGGIPCQRCARLNRSCGFTGQPSRDVDYTASRNVSREPTETTQRLRYMEKLLTHFTGRSNLDATTLKNLADAVDRQRGEARFGQDAGGAADDGSQSSEYLGVDAENFTVQPLESNIAHYSGEFSHWNFSMRIKQWIENCNKEYRGGEQPADPLTFKEYYRAEELQSPSNTVMSLSSLPPPYITGYLVDAFFKHAESNYFFVERSWLMDKINLAYENPGVFTHRDVGTVGMILIILAIGTQYAYLDNEGERLTRLGKSMHPSEGSPYEEDAVGVMFYQRACMLVPDIITIASLESVQACLLIGLYTLPLDASGLSYIYLNLALKLAIQNGMHRNYSTNAWPAVIRETRNRVFWTVHAIERRVGIFHGRPLSIAPSEVDATLPSLDPSVWPVDLPANTAHMLATLQLNKTLTKVCREIQLLKTGTRQEAAEVFNRLIETKNDLHKWWDILPTNKFNKDFSGAISFTRSDAHLRLEYCLLRMYAGRPFVFPRGLGRYNNVAATEASPSTSGATPTSSASTSKTHPRALLVTDCIEAALGIIETCKALDKTIGLARASYTEFSACRAALLVIVTQCLQKRTDRLRDALREGMVMIKSMAAWGESARSEVSLLEVFECAVDKLDTAASGNGNGAGSNGIMTDEESGYERFKKWQMLWKQPSSGAPTTTASAMGGGGPESTRMEDDDGDSIALSSATGAGHPEPNGPPHGMPAGVGGGGIGGPIPPHPLEFWRGALTRQEPASTAMQMPSTFFGTDETFASFQQTLDEYSMSMQAGFSPLMDGAGQTPGSGLGGNVWMNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YGX3</accession>
    <name>A0ABR3YGX3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006759</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000369">
        <property type="protein sequence ID" value="KAL1887006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031833">
        <property type="entry name" value="DUF4748"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41800">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41800:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15932">
        <property type="entry name" value="DUF4748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="81" mass="9174" checksum="E5D4D40978CD1661" modified="2025-10-08" version="1">MNTAKSFWAGWGALCAAGGTAYYFAKQSINADRALKMEELRKKKQQIEQLRMDEDIKGVKPDKGLYETPKPFKSPKGDRFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH51</accession>
    <name>A0ABR3YH51_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006657</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000343">
        <property type="protein sequence ID" value="KAL1887187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052061">
        <property type="entry name" value="PTE-AB_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260">
        <property type="entry name" value="UPF0644 PROTEIN PB2B4.06"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260:SF1">
        <property type="entry name" value="UPF0644 PROTEIN PB2B4.06"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="2">
        <location>
            <begin position="184"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1887187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="281" mass="30219" checksum="594B58A32339A309" modified="2025-10-08" version="1">MFARSVKTMSSSSALARACAQARASQTAPVASSLKHSLRSSAPIIINRAYQRQAAAPSVTSSAVPSSSRKLAQLATALPTSSTDAANPNPFANDPSALTMEQHEELLLDVIAGHSQSAEFKARECVRVIRAPLMLAEEHLETSLTYSTLCGEGKMACRPIIFLDEQAGALLGYYHMGRRLAGHQGIVHGGFQAMLLDECMARATFPRLPAKISVTANLKVDYKAPLPVNRYIVLKAETVKVEGRKAWVEGSVNDAHTGEVYASASGLFIQPKWADKMAPIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YH60</accession>
    <name>A0ABR3YH60_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitogen-activated protein kinase-binding protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000347">
        <property type="protein sequence ID" value="KAL1887158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052779">
        <property type="entry name" value="WDR62"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45589">
        <property type="entry name" value="WD REPEAT DOMAIN 62, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45589:SF1">
        <property type="entry name" value="WD REPEAT DOMAIN 62, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="784"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1000"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="787"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="845"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1001"/>
            <end position="1033"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1887158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1033" mass="113331" checksum="C93F0F805FF3EF2E" modified="2025-10-08" version="1">MTTTPSNRLKLTPSNSPYLNLKPSRSLLRGRPSITTTDPIMQSRITLQRVVGTTCTSATGFDSVQSSFAYVAGGAAVVVNVDPNQKQRYACRYNQRFYRARPTAIPIYSVSTQSSNVVNTPISTPKANDSRNRVSSGLRESGFGVSEYSESNKTWTSRERIKAASCLALSRDGRFLAVGEAGYAPRVLIFGLQECSSDTPLVSISEHSFGVRAVAWSHDTRFLASLGTINDGFLYLWKVDSRTGAAKLFQQNRCTSSVKDMVWMGNNLITLGVRHVKSWKVEDSNSSSPVKTRFTNDNALSSPVQPQKTLPGRNVLLGSLIDSTFTCAAVVDDSRTIICSEAGDVCLLDDDGKQMKLQRVLRLEFSISSITIRDLTAYVSGKAGQFVTLDVAKVVDFQDDSILESTQAPNGIVAMGFLRNNFVTIDLNRSIEIWHRDYLPGQMKDDPSRILIPGHDEAIVGVQTLPQPNLHAADFMTWSGSGKMIQWDLDGQIKSTFDVPIENVPTGSDLDPENQLTVVRADSSGNLIVTGDRIGVLRVVDLKTGEWLLDTKAHASEVQDITIYDDKKTSKLIVATCGRDRTAQLFHRAENGVIRHFQTLEFAAKVVQILIPSDEKILTCSLDRTLQIYDLVPRNSDCDDLAAVPSRVLSLKASPTSMVMNSDSKNQSVFVSLLDRSICQYDISAGRLQNSFKCFDESGAESAVLERLLLDQTAGREQERLLGISNTDKSVRVYDAQTGSFLGREWGHTEAINGLALLNTDDCDLKAATVASDGTLMLWSVDTQDGSASSTSRDSSPPKESGAASRPPLRRVLSKAELAEYQKPTVASAGRRSPPRTLTRRTSRQFLTTPTMKTPQSQISASEPIIETTPSRKGGSMACRDTSPPLSPRRRVLRRPSLPALNTASQKKTPQNIKGFGSLNMATEQACRTLRAYRKKLASTEPISQATLEELDQELRLTVSALSNRAIRSKAMNESMLSGLLDEYSERLVSMLDEKLRLSFPQRSDGSQDSGFLSSEDSVRPRTSSGETNSTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YHU5</accession>
    <name>A0ABR3YHU5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Kinetochore protein Sos7 coiled-coil domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cpir12675_006375</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000290">
        <property type="protein sequence ID" value="KAL1887888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037475">
        <property type="entry name" value="Sos7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048781">
        <property type="entry name" value="Sos7_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37329">
        <property type="entry name" value="KINETOCHORE PROTEIN SOS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37329:SF1">
        <property type="entry name" value="KINETOCHORE PROTEIN SOS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20882">
        <property type="entry name" value="Sos7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinetochore protein Sos7 coiled-coil" evidence="3">
        <location>
            <begin position="65"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="100"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="201"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="34"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAL1887888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="288" mass="32334" checksum="0D0D5598731638DB" modified="2025-10-08" version="1">MTMVSEILHELEQLQNQSLSILKLSEPITASALTSSSNRRSDASSTSFDAPTPSSLEADLAHYRELFSKLRFSYVEQVTKEKFIRAIVGDPPLIVTPLENVELEKENLAAKAALKALKLEVAALVADLEKRARDLSRRTAQIRIDTAKLKDLPQEIALVEESLKNLRHKREEMDKQANGNLELALPLGRTLELAEERKTHMGALDRELEQLRARVPRKKKELERLKAEIAPLDAKKTTSTAAAREARRRKEAALGGVEDDLEERGRWYRASEAILARVLEGEADTRQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YI14</accession>
    <name>A0ABR3YI14_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">GIN4</name>
        <name evidence="14" type="ORF">Cpir12675_006537</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 16">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 16">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JAWDJO010000317">
        <property type="protein sequence ID" value="KAL1887473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.220">
        <property type="entry name" value="Fungal kinase associated-1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031850">
        <property type="entry name" value="Fungal_KA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043024">
        <property type="entry name" value="KA1_sf_fungal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF110">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16797">
        <property type="entry name" value="Fungal_KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="109"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="534"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="627"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="716"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="812"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="963"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="534"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="629"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="716"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="736"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAL1887473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="1126" mass="126960" checksum="9260664B0D8E6425" modified="2025-10-08" version="1">MGELRQPLSDAPTRANQGRRYSSLPAGIRGNGKKYRAPELVAIMGDGPVTAMQQDEVMRSERAATHSLRHKALHNAYVQQNDTGHVYRQPSIDLSARCESGYKINIGPWKLAHTLGQGASAEVKFCRHRVTSQPAACKIVSKHSSTLIQAGSLAALDRIDAHMQQKVKNQMRVPVAVEREVAILKLVQHPNIMKLYDIWENGEYIYLILELVDDGDLFTLITNNGRLAEEAAISLFRQIMSAMTYCHYFKICHRDLKPENILVTHDGQVKIADFGMAALHQTETHKLHTACGSPHYAAPELLKAHRYLGNRADIWSMGVILFAMLTARLPFDEEQVSLVHAKVKRGEYEMPEFLSIEAKDLIRRMLEVNPDRRITMYDMWRHPLIMKYQAFDNLNPVTGQPPDVSLKFEPQPLRREEIDGQIVHQLRTLWHMFSEEDIVSNLVQKSPNTQQAFYWLLRNYRERQLEDFKPEIAHSRSDYHHFTPSAWKRKISTCEFTSGRSVSRFTVISQVAETEVETVASYDPFNVNKYSAADSSLASGNEPSRTKVTIHRRPSAHGQRDQSFSSNTQRIRRTAGTVASIRTARGTRIGPKTPSIGSMHSGKGVMYARPVPVHKRPAVNFTHIRRKSSAASRNGSIHMSSSGRGHSQRYMHGARGAHGSRDVRRRPSVKVPRPGTMQISQTQDSALIDEEVRKFSSRIARDLDTAFNTSIVAEPSITGSLGFSSPTDTNEPKTPESFQSTDQTLVQDSTAEQGTWKDRPLPPLPERLKLLATSMPSKDDRRMVTAPAQLIRSNTNIEIFDTDADYLGKSSADKIRASSGPTQTTQRRGKGGEEKALRILESTENSIRVVNSPKRPLTGASFMDRVMKDRKRESGTSMMSDYGRRASTAMPKLGYHDESVSKRKPSWFQRLSSYSHPNEMVEAGDRLYANQRTDHGSDSSSINGLQNKKKKRFGLLFWKTSKDGKQDADTTTPSISPITRAPTPKPQDPVHENWIARMFRIKPATEYLCFDMSRKDARNDLADLFREWKSFGMRDVAVDKDRNIVFARVSGKNSLGIKEVALAAEIMTVIEHGSNRSLSIVRFTQERGAASSFHTVVKTTKEVFSRRNKLVADRQKSRMMIKTLNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJ61</accession>
    <name>A0ABR3YJ61_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNA helicase HEL117</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006206</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000265">
        <property type="protein sequence ID" value="KAL1888351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044688">
        <property type="entry name" value="SCI-1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34117">
        <property type="entry name" value="STYLE CELL-CYCLE INHIBITOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34117:SF1">
        <property type="entry name" value="STYLE CELL-CYCLE INHIBITOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="381" mass="43987" checksum="F803182194A9B753" modified="2025-10-08" version="1">MGNERRTSSKASHSSHRSHRRYTRSRSPRVDDHDHSSHRSRRSHRTRDRTHDHRHDTSGSHKRRLDTAVAPARAVELPFEARPLHKRDFKAFLPLFAYYLDLQKQKDLSDMDEREAKGRWKSFLGKWNRGELAEGWYDSVMFERSKELYGQDSWSFEEEPEKEGDARREARGRTGSYDREGSFSISQEKPSRPPASHSDSDSDSNPDDVGPAPAPVHRSNTTPHGASVPSLSDLELRDQARLEDCQASIDDLRYARKQDRILQKERLEELVPRADAGSRERKLEKKSEIREKLRAVSPGGGVPEHDDNDLIGGGDSLAELKCAKESAQRKKTEREKRREEVWRAREAEREERAREYREKEDATVRMLREFARNRGGASSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJB6</accession>
    <name>A0ABR3YJB6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mannan endo-1,6-alpha-mannosidase</fullName>
            <ecNumber evidence="3 8">3.2.1.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cpir12675_006236</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CMW 12675</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Random hydrolysis of (1-&gt;6)-alpha-D-mannosidic linkages in unbranched (1-&gt;6)-mannans.</text>
            <dbReference type="EC" id="3.2.1.101"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyl hydrolase 76 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.101" evidence="3 8"/>
    <dbReference type="EMBL" id="JAWDJO010000269">
        <property type="protein sequence ID" value="KAL1888254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014480">
        <property type="entry name" value="Mannan-1_6-alpha_mannosidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145:SF38">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016302">
        <property type="entry name" value="Man_a_manosd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="416"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="422"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR016302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAL1888254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="500" mass="54013" checksum="435311477C86F69A" modified="2025-10-08" version="1">MAEFYKSAKKAATAATVLVAALPPNSLIVDNSENIKGVARTLAQGVMSYYQPDNPAILIGDLPDPYYWWEAGAMWGSMIDYYHYTNDSTYNDLAIEALLAPVNTGTNFDFMPIEHASEEGNDDLGFWGFAVMSAAERNFPQPNPDVPSWLQLSINIFNSLESRWNTTACGGGLLWQIYESSPHGLNYKNTVSNGGFFQLAARLARVTGDKKYLDWAVKVWDWTENIGMIGTDYIVYDGAHAAADCRDTNPVSFSYSNAIYMYGAAVLANVTGEKIWADRAQGILTATSKRFFYPEANAANVMYESACETVGTCNEDMKSFKAYLSRFMWKSTEMLPDIKPQVNKLLETSALAAVKTCTAGESGSECGMRWYTGSHDGISGLGQQMSALEIVQGLLVDGITGPLKSEEVQVIRKKPWADEEPAVSSSSSSAAASTLTSAPATPPASILPTLTNTAAADATNLAIAPPIVAVKRDTDSSASVHGPTMRAAYIFAAVLAAAFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJL6</accession>
    <name>A0ABR3YJL6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Casein kinase substrate phosphoprotein PP28 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cpir12675_006145</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000258">
        <property type="protein sequence ID" value="KAL1888504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019380">
        <property type="entry name" value="Casein_kinase_sb_PP28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039876">
        <property type="entry name" value="HAP28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22055">
        <property type="entry name" value="28 KDA HEAT- AND ACID-STABLE PHOSPHOPROTEIN PDGF-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10252">
        <property type="entry name" value="PP28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Casein kinase substrate phosphoprotein PP28" evidence="2">
        <location>
            <begin position="131"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="73"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAL1888504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="254" mass="27551" checksum="80786277E36F13F0" modified="2025-10-08" version="1">MARGGSAAASSRGRGKFRSFTRGGGKSFSRNLGMNSDGTQMSMWGEAASENSDEDDESDSGSEASDSDDESDSAGPSNTAATSAEASREERRKDKKARKNAALAKKKVVQAGDLPPSDSEEESDDNTPPANPNHSKKAAASVASQRQADPAVKNITQDVEDMSMNRRERDAAAAAEAKLRYQKMHEQGKTDEAKADLARLRLVREKRAAEAAQRLAEKEEREAKEAERQEELKVREAKRREAALGPTKKPKKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJM1</accession>
    <name>A0ABR3YJM1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mitochondrial import inner membrane translocase subunit Tim21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">TIM21</name>
        <name evidence="11" type="ORF">Cpir12675_006475</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the TIM23 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion inner membrane</location>
            <topology evidence="9">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TIM21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000306">
        <property type="protein sequence ID" value="KAL1887629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.320">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit Tim21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013261">
        <property type="entry name" value="Tim21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038552">
        <property type="entry name" value="Tim21_IMS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13032">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13032:SF6">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08294">
        <property type="entry name" value="TIM21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="31"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="48"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAL1887629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="254" mass="28491" checksum="1823C1A6028C560F" modified="2025-10-08" version="1">MISPRLSQITERLTTTALAGSLRPVIANTHHNAARSSRGFSTSGSKSQPMHQAQASVQSQPQTTTPQPRRRLVTAFNDDGVVPWSKLSLREKTSRTTQQSFNFAVVAVGVVLTAAVIYVLFDEVFAPESKVAQFSRAVSLIKKDPRCIAILGDPEDIWAHGEPTTNKWQRSRPISSTLEKDSRDVEHLIMQFYVEGPKAMGVVHLHMSRHPKADDFEYKYLFLDAKGHDRIYIKRDETKGRSKKPFSFLGISWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YJW4</accession>
    <name>A0ABR3YJW4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cpir12675_006109</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000253">
        <property type="protein sequence ID" value="KAL1888608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="358"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAL1888608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="392" mass="42319" checksum="B6269CA92D7BAD78" modified="2025-10-08" version="1">MSNRQSGYAPWSQMTPSNDASHSHMMNHHIPQGHGSHHPQQQQQPPSGPPHTTSDSSITPPPTTSRSVTSSPPKAGMTPEQREMKRQQNQVRRDSKTTSRIRRANSNPYGNDIPGGPPSAGLGSVYSGSPAGAPATGSMPMMGENPGAPMQSPSYLHPYSPPLAEGQSHYQYQSPHMQSTYGMPMDYSGFQQHPQSSYARGRHPPPSNIPMDPNASMMYGAVPSMMSPSMPQPSPHGHSHTHSGHVHPHGAHPHAVAPPPHMGAAEANNNNHVRVVQTRPKPQCWEHGCNGRQFSTFSNLLRHQREKSGQAAKATCPNCGAEFTRTTARNGHLLHDKCKKRSPNPPVPNGSTASGTNQPAGQPAQTQVQAQGQQPQSRQQPPSQGQQQQPQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKJ7</accession>
    <name>A0ABR3YKJ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">E3 ubiquitin protein ligase</fullName>
            <ecNumber evidence="15">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">BRE1</name>
        <name evidence="19" type="ORF">Cpir12675_006214</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CMW 12675</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 15">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 15">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the BRE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="15"/>
    <dbReference type="EMBL" id="JAWDJO010000265">
        <property type="protein sequence ID" value="KAL1888358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16499">
        <property type="entry name" value="RING-HC_Bre1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058643">
        <property type="entry name" value="BRE1-like_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013956">
        <property type="entry name" value="E3_ubiquit_lig_Bre1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23163:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE BRE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23163">
        <property type="entry name" value="RING FINGER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08647">
        <property type="entry name" value="BRE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26095">
        <property type="entry name" value="CC_Bre1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="19" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10 15" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="11 15 16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15 19" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 15" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9 15" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 14 15" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="18">
        <location>
            <begin position="685"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="249"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="200"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="349"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="472"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="577"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="19">
        <location>
            <position position="734"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00059679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU365038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAL1888358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <sequence length="734" mass="83719" checksum="F7A007839FF047A6" modified="2025-10-08" version="1" fragment="single">MPVATPNPTTTTLSSVSRVDKMDERKRPASTANNSDEAAPPRKRHAANGNEREDYEKYENQPEEVWITNFTKGAIFRRMHEYRRESQTFSSRLEELHKRSLYHDDHIRIVDAWWRQFVDELELLVDSKVPSADTVPSEQPYLSRVAFHDTVDFQRHLDEKKRSLASRAEALVGRIAASRGQINPNVTTLESEVSTLLAVQKEYLVKLDRLSNEKQELTEQLNLASLRYFKAEKKLDRAKSAQVTELEQQALSRDARSGQGFNGNAEGSKAAKPSTNHAELKAKIEEEQASVKKQQEQIDSLLADIKALQDENTKLRMSKEPASGTEEDFAHTELFKSLRSKTEDLIKQVNHLETTNSQIRDECEKLLAERTAFKRQLDSDTQAVTTELDNELLSRDSDLARIRASRDEHMTELNSNKQVLDQERTALNHLKELVAAKDDKIASLESRIARLEPPAEDQEMADVEAKLDEVPEEELRAKFRKLQRDYDSINHELPSISTAYKKAMALAHNKVMNLEALERKVELILAEKGRVDQKYFAARKDADMRVTEINTMRRQNSKSAEIIAQLKEVETSNRCTMANLEKQLAQLKKANIALAAEHKKLEGASIEATRKSEGALKEVQNLKELISVRDTSISSLRSITLEKDMESSRLKAKVDSLTKDRDQWRRKAEGNSSDVEHNLRTLMLCTICNDKFKDTALKTCGHLFCKACVQDRLTNRMRKCPNCSKAFDKMDIMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR3YKV5</accession>
    <name>A0ABR3YKV5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Nucleoporin POM152</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cpir12675_006148</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratocystis pirilliformis</name>
        <dbReference type="NCBI Taxonomy" id="259994"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Microascales</taxon>
            <taxon>Ceratocystidaceae</taxon>
            <taxon>Ceratocystis</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2024" name="IMA Fungus" volume="15" first="0" last="0">
            <title>IMA Genome - F19 : A genome assembly and annotation guide to empower mycologists, including annotated draft genome sequences of Ceratocystis pirilliformis, Diaporthe australafricana, Fusarium ophioides, Paecilomyces lecythidis, and Sporothrix stenoceras.</title>
            <authorList>
                <person name="Aylward J."/>
                <person name="Wilson A.M."/>
                <person name="Visagie C.M."/>
                <person name="Spraker J."/>
                <person name="Barnes I."/>
                <person name="Buitendag C."/>
                <person name="Ceriani C."/>
                <person name="Del Mar Angel L."/>
                <person name="du Plessis D."/>
                <person name="Fuchs T."/>
                <person name="Gasser K."/>
                <person name="Kramer D."/>
                <person name="Li W."/>
                <person name="Munsamy K."/>
                <person name="Piso A."/>
                <person name="Price J.L."/>
                <person name="Sonnekus B."/>
                <person name="Thomas C."/>
                <person name="van der Nest A."/>
                <person name="van Dijk A."/>
                <person name="van Heerden A."/>
                <person name="van Vuuren N."/>
                <person name="Yilmaz N."/>
                <person name="Duong T.A."/>
                <person name="van der Merwe N.A."/>
                <person name="Wingfield M.J."/>
                <person name="Wingfield B.D."/>
            </authorList>
            <dbReference type="PubMed" id="38831329"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CMW 12675</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAWDJO010000258">
        <property type="protein sequence ID" value="KAL1888507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001583280">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056541">
        <property type="entry name" value="Ig-like_POM152"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056542">
        <property type="entry name" value="Ig-like_POM152_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056543">
        <property type="entry name" value="Ig-like_POM152_9th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056544">
        <property type="entry name" value="Ig_POM152"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037701">
        <property type="entry name" value="Pom152"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056540">
        <property type="entry name" value="TMD_POM152"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28206">
        <property type="entry name" value="NUCLEOPORIN POM152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28206:SF1">
        <property type="entry name" value="NUCLEOPORIN POM152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24312">
        <property type="entry name" value="Ig-like_POM152"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24519">
        <property type="entry name" value="Ig-like_Pom152_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24527">
        <property type="entry name" value="Ig-like_Pom152_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23664">
        <property type="entry name" value="Ig_Pom152"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24097">
        <property type="entry name" value="TMD_POM152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="156"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin POM152 N-terminal transmembrane" evidence="4">
        <location>
            <begin position="88"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin POM152 first Ig-like" evidence="6">
        <location>
            <begin position="224"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin POM152 Ig-like" evidence="5">
        <location>
            <begin position="473"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin POM152 immunoglobulin-like" evidence="3">
        <location>
            <begin position="581"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin POM152 Ig-like" evidence="5">
        <location>
            <begin position="781"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin POM152 immunoglobulin-like" evidence="3">
        <location>
            <begin position="896"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin POM152 ninth Ig-like" evidence="7">
        <location>
            <begin position="1095"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin POM152 Ig-like" evidence="5">
        <location>
            <begin position="1177"/>
            <end position="1261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF24519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAL1888507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001583280"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1278" mass="143071" checksum="86937FDA402102BA" modified="2025-10-08" version="1">MDSTPRISTGAFPKTPGDSVRPRRTFHQKPPSSAFPRPPSQTPEKKPSLSSLGGPAKPPPRNNALPIAPQVNARPSANSPVIPLDLLDGPQQRILAFAVWSILLLWRCYHWVQLVEEDESSPMLFLWWVLVDWGFIFGLSALRIPWLELAGSSRLIIFVMHAIANYMLMFNVSLPFQFGVAALWKAFFDSEIAISEHNVRVSHIIHNSSLIMGKQIINILPEGTAVLNRDQIPYCIGPHSKTVQVPIQFNGTIPVEIEFTRVDILTNIAETIKLSKKEVSQIVRQIRQQQAEVDDEMVEVFYPVKKTGVYRLSKVLDEYKLDVQRHSRETYIVQCPKASIRMPDTTDRCIRDLSDLFFDVDGTPPLKIKYDRTINGKDRSFHFQSLQPDDFVSPMFGGAALSPNGDENYSWARSSKISVGINESMTNSGEWEYFVHEVHDAFGNTVNYTTPEDDLDHEPFKSSLAKKLTVKERPRARLNGCDLRNPLLAAKGKPMGFPVSVSMPGGIGVASDHQLEWDFSPLASLSNSGDHGDKASTFQYKAKSSKDIPSVTESGLYTLKKVSSGGCEGEIEEPSSCMLINPMEPTLKVKSEPISDKCAGNSVGLRVDLDLMGTPPFVVRYDVRSSSGLRYEKVTVNGLRHQLDLRPTDAGHHTYNFKTVSDSVYKDIPLTGMDYNLEQDVKPAASAFILSNDRSACLDEKAEIDVLFQGEPPYNLEYEIVHEGRRKASKISGIETSTFTITTEPLVKGGEYIIALNSVSDTRGCPTFLKDQMKVSVRRQKPRVGFGFIESRRRVLAVENSKLSLPVRLQGEGPWTVSYRNSIDGIVLSKVLNNANDLILVNSKGIYELVDVFDKQCHGSVDSDAFQFEVNWFDKPELSLQ
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